<PAGE> 1
Exhibit 11.1
NEOPROBE CORPORATION AND SUBSIDIARIES
COMPUTATION OF INCOME (LOSS) PER SHARE
<TABLE>
<CAPTION>
Three Months Ended Nine Months Ended
September 30, September 30,
--------------------------- ---------------------------
2000 1999 2000 1999
----------- ----------- ----------- -----------
<S> <C> <C> <C> <C>
Weighted average number of common shares outstanding
used in computing basic income (loss) per share 25,855,341 23,044,405 25,628,355 22,988,908
Add net shares issuable pursuant to stock option plans,
less shares assumed repurchased at the average market price 215,599 - 356,820 -
Add net shares issuable pursuant to outstanding warrants,
less shares assumed repurchased at the average market price 4,453 - 670,081 -
----------- ----------- ----------- -----------
Weighted average number of common shares outstanding
used in computing diluted income (loss) per share 26,075,393 23,044,405 26,655,256 22,988,908
=========== =========== =========== ===========
Income (loss) attributable to common stockholders $ 504,090 $(3,536,832) $ 351,873 $(8,127,047)
Basic income (loss) per share attributable to common stockholders $ 0.02 $ (0.15) $ 0.01 $ (0.35)
=========== =========== =========== ===========
Diluted income (loss) per share attributable to common stockholders $ 0.02 $ (0.15) $ 0.01 $ (0.35)
=========== =========== =========== ===========
</TABLE>