KEMPER GOVERNMENT SECURITIES TRUST GNMA PORT SERIES 21 & 22
24F-2NT, 1994-02-24
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<PAGE>
                               February 15, 1994



Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C. 20549-1004

     Re:  RULE 24F-2 NOTICE FOR KEMPER GOVERNMENT SECURITIES
TRUST, GNMA PORTFOLIO, SERIES 21 & 22
          FILE NO. 33-12021


Gentlemen:

     As Sponsor of the above mentioned trust, we are submitting
the following
information required by Rule 24f-2 promulgated under the
Investment Company Act
of 1940, as amended.  We also have wired funds in payment of the
fee prescribed
by subsection (c) and the opinion of counsel specified in
subsection (b)(1)(v)
of said Rule.

     (i)   Fiscal year for which notice is filed: Year Ended
DECEMBER 31,1993

     (ii)  Number of securities registered other than pursuant to
Rule 24f-2 
           and remaining unsold at the beginning of the above
fiscal 
           year: 0 UNITS

     (iii) Number of securities registered other than pursuant to
Rule 24f-2
           during the above fiscal year: 0 UNITS

     (iv)  Number of securities sold during the above fiscal
year: 9,324,965

     (v)   Number of securities sold in reliance upon
registration
           pursuant to Rule 24f-2 during the above fiscal year: 
9,324,965

     ----------------------------

     (1)   Aggregate sales price to the public of
           securities sold in reliance upon
           registration pursuant to Rule 24f-2                   

 $2,935,091.81

     (2)   Less actual aggregate redemption of
           repurchase price of securities redeemed
           or repurchased during the fiscal year                 

 $3,038,054.87

     (3)   Plus the actual aggregate redemption or
           repurchase price of securities previously
           applied in filings pursuant to
           Section 24f-2                                         

  $0      
                                                                 

  -------
                                                                 

  $0
           Amount of filing fee computed at one
           twenty-ninth of one percent (1/29 of 1%)
           of above total:                                       

  $0
                                                                 

  -------
                                      Very truly yours,
 
                                      KEMPER SECURITIES GROUP,
INC.

                                   By  
                                     
- -----------------------------   
                                      Michael J. Thoms

<PAGE>





                               February 15, 1994


Kemper Securities Inc.
77 West Wacker Drive
5th Floor
Chicago, IL 60601


     Re:  Kemper Government Securities Trust, GNMA Portfolio,
Series 21& 22
          File No. 33-12021

Gentlemen:

  We have served as counsel for Kemper Securities, Inc. as
Sponsor and
Depositor of the above described Trust, in connection with the
preparation,
execution and delivery of a Trust Indenture and Agreement
relating to such Fund
pursuant to which the Depositor has delivered to and deposited
the Securities
listed in Schedule A to the Trust Indenture and Agreement with
the Trustee and
pursuant to which the Trustee has issued to or on the order of
the Depositor a
certificate or certificates representing Units of fractional
undivided interest
in and ownership of the Fund created under said Trust Indenture
and Agreement.

  In connection therewith, we have examined such pertinent
records and
documents and matters of law as we have deemed necessary in order
to enable us
to express to opinions hereinafter set forth.

  Based upon the foregoing, we are of the opinion that the
certificates
evidencing the Units in the Fund constitute valid and binding
obligations of
the Fund in accordance with the terms thereof.

                            Respectfully submitted,



                            CHAPMAN AND CUTLER




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