AGOURON PHARMACEUTICALS INC
S-8, 1996-11-26
PHARMACEUTICAL PREPARATIONS
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As Filed with the Securities and Exchange Commission on November  26, 1996

                                                  Registration No._______

=========================================================================

                      SECURITIES AND EXCHANGE COMMISSION

                           Washington, D.C.  20549

                              __________________

                                   FORM S-8

           REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933

                       AGOURON PHARMACEUTICALS, INC.

         (Exact name of registrant as specified in its charter)

           California                                  33-0061928
   (State or other jurisdiction                    (I.R.S. Employer
 of incorporation or organization)               Identification Number)

                        10350 North Torrey Pines Road
                         La Jolla, California  92037
                 (Address of Principal Executive Offices)

            AGOURON PHARMACEUTICALS, INC., 1996 STOCK OPTION PLAN
                             (Full title of plan)

                                 PETER JOHNSON
                          Agouron Pharmaceuticals, Inc.
                         10350 North Torrey Pines Road
                           La Jolla, California  92037
                                (619) 622-3000
       (Telephone number, including area code, of agent for service)

                      Calculation of Registration Fee

============================================================================

   Title of       Amount to       Proposed      Proposed       Amount of
  securities         be           Maximum       Maximum      Registration
    to be        registered(1)    offering      Aggregate        Fee
  registered                      price per     Offering 
                                  unit (2)      Price (2)
- ---------------------------------------------------------------------------

  Common          2,000,000       $49.375      $98,750,000    $29,924.25
 Stock No           Shares
 par Value

Options to        2,000,000         N/A            N/A           N/A
 Purchase   
 Common
  Stock

(1)     In addition, this Registration Statement also covers any additional 
        shares of Common Stock which become issuable under the Agouron 
        Pharmaceuticals, Inc. 1996 Stock Option Plan by reason of any 
        stock dividend, stock split, recapitalization or other similar 
        transaction effected without the receipt of consideration which 
        results in an increase in the number of the Registrant's 
        outstanding shares of Common Stock.

(2)     Calculated in accordance with Rule 457(h) under the Securities 
        Act of 1933. 

=========================================================================

[PAGE] 
                                    Part II

              Information Required in the Registration Statement


Item 3.  Incorporation of Documents by Reference.

     The following documents filed by AGOURON PHARMACEUTICALS, INC. (the 
"Company" or "Registrant") with the Securities and Exchange Commission are 
incorporated by reference in this Registration Statement:

     (1)     The Company's Annual Report on Form 10-K for the fiscal year 
             ended June 30, 1996.

     (2)     The Company's Quarterly Report on Form 10-Q for the quarter 
             ended September 30, 1996.

     (3)     The description of the Company's Common Stock contained in the 
Company's Form 8-A Registration Statement filed April 17, 1987, including any 
amendment or report filed for the purpose of updating such description, 
together with the Company's Form 8-A Registration Statement filed on November 
7, 1996, in which there is described the terms, rights and provisions 
applicable to the Company's outstanding Common Stock under the Rights 
Agreement dated as of November 7, 1996, between the Company and Chase Mellon 
Shareholder Services, L.L.C., including any amendment or report filed for the 
purpose of updating such description.

     In addition, all documents subsequently filed by the Company pursuant to 
Sections 13(a), 13(c), 14 and 15(d) of the Securities Exchange Act of 1934, 
prior to the filing of a post-effective amendment which indicates that all 
securities offered have been sold or which deregisters all securities then 
remaining unsold, shall be deemed to be incorporated by reference in this 
Registration Statement and to be a part hereof from the date of filing of 
such documents.


Item 4.  Description of Securities.

     Not applicable.


Item 5.  Interests of Named Experts and Counsel.

     Gary E. Friedman, Esq., who has provided the opinion to the Registrant 
on the validity of the securities being registered which is attached as 
Exhibit 5 to this Registration Statement, is Vice President, General Counsel 
and Secretary of the Registrant.


Item 6.  Indemnification of Directors and Officers.

     Section 317 of the California General Corporation Law generally provides 
indemnification to officers and directors of the Company against expenses, 
judgments, fines and amounts paid in settlement under certain conditions and 
subject to certain limitations.

     Article VII of the articles of incorporation of the Company provides 
that liability of the directors of the Company for monetary damages shall be 
eliminated to the fullest extent permissible under California law.  Further, 
Article VIII of the articles of incorporation authorizes the Company to 
provide indemnification of agents (as defined 

                                       II-1
[PAGE] 

in Section 317) for breach of duty to the Company and its shareholders 
through bylaw provisions or through agreements with such agents, or both, in 
excess of the indemnification otherwise permitted by Section 317, subject to 
the limits on such excess indemnification set forth in Section 317.

     Section 3.15 of the bylaws of the Company authorizes the Company to 
indemnify any person who was or is a party, or is threatened to be made a 
party, to any proceeding (other than actions by or in the right of the 
Company to procure a judgment in its favor) by reason of the fact that such 
person is or was an agent of the Company, against expenses, judgments, fines, 
settlements and other amounts actually and reasonably incurred in connection 
with such proceeding if such person acted in good faith and in a manner such 
person reasonably believed to be in the best interests of the Company.  
Section 3.15 also authorizes the Company to indemnify any person who was or 
is a party, or is threatened to be made a party, to any threatened, pending 
or completed action by or in the right of the Company to procure a judgment 
in its favor by reason of the fact that such person is or was an agent of the 
Company, against expenses actually and reasonably incurred by such person in 
connection with the defense or settlement of such action if such person acted 
in good faith.

     Any indemnification under Section 3.15 is to be made by the Company only 
if authorized in the specific case upon determination that indemnification of 
the agent is proper in the circumstances because the agent has met the 
applicable standard of conduct required by Paragraphs 3.15.2 or 3.15.3 of the 
bylaws.

     Pursuant to authorization provided under the articles of incorporation 
and the bylaws, the Company has entered into indemnification agreements with 
each of its present directors.  The Company has also entered into similar 
agreements with certain of the Company's officers who are not directors.  
Generally, the indemnification agreements attempt to provide the maximum 
protection permitted by California law as it may be amended from time to 
time.  Moreover, the indemnification agreements provide for certain 
additional indemnification.  Under such additional indemnification 
provisions, however, an individual will not receive indemnification for 
judgments, settlements or expenses if he or she is found liable to the 
Company (except to the extent the court determines he or she is fairly and 
reasonably entitled to indemnity for expenses) for settlements not approved 
by the Company or for settlements and expenses if the settlement is not 
approved by the court.  The indemnification agreements provide for the 
Company to advance to the individual any and all reasonable expenses 
 (including legal fees and expenses) incurred in investigating or defending 
any such action, suit or proceeding.  In order to receive an advance of 
expenses, the individual must submit to the Company copies of invoices 
presented to him or her for such expenses.  Also, the individual must repay 
such advances upon a final judicial decision that he or she is not entitled 
to indemnification.

     Section 3.15 of the bylaws also provides that, in the event of a 
determination by the Board of Directors of the Company to purchase insurance 
for certain of its agents, the Company shall purchase and maintain insurance 
on behalf of any such agent against liability asserted against or incurred by 
the agent in such capacity or arising out of the agent's status, whether or 
not the Company would have the power to indemnify the agent against such 
liability under the provisions of Section 3.15.

     The Company has in effect directors and officers liability insurance 
policies which insure directors and officers of the Company.  Although the 
Company intends to renew the policies on or before their expiration date, 
there can be no assurance that the policies will be renewed on terms 
acceptable to the Company.  Under the policies, the directors 

                                       II-2
[PAGE] 

and officers of the Company are insured against loss arising from claims made 
against them due to wrongful acts while acting in their individual and 
collective capacities as directors and officers, subject to certain 
exclusions.  In addition, the policies insure the Company against losses for 
which its directors and officers are entitled to indemnification, subject to 
certain retentions payable by the Company.  The policies are "claims made" 
policies and provide coverage only for losses arising out of claims first 
made against the Company and reported to the insurer during the policy 
period.


Item 7.  Exemption from Registration Claimed.

     Not Applicable.


Item 8.  Exhibits.

4.1      Restated Articles of Incorporation dated October 20, 1990, 
         incorporated by reference to the Company's Form 10-Q for the 
         Quarter ended December 31, 1992.

4.2      Rights Agreement dated as of November 7, 1996, between the Company 
         and Chase Mellon Shareholder Services, L.L.C., which includes the 
         Certificate of Designation, Preferences and Rights of Series B 
         Participating Preferred Stock as Exhibit A, the Form of Rights 
         Certificate as Exhibit B and the Form of Summary of Rights as 
         Exhibit C, incorporated by reference to Exhibit 4.4 of the Company's 
         current report on Form 8-K dated November 7, 1996.

5        Opinion of Gary E. Friedman, Esq.

23.1     Consent of Price Waterhouse LLP.

23.2     Consent of Gary E. Friedman, Esq. (included in his opinion filed as 
         Exhibit 5).

24       Power of Attorney (contained on signature page of this Registration 
         Statement).

99.1     The Agouron Pharmaceuticals, Inc. 1996 Stock Option Plan.

99.2     Form of Notice of Grant.

99.3     Agouron Pharmaceuticals, Inc. 1996 Incentive Stock Option Agreement.

99.4     Agouron Pharmaceuticals, Inc. 1996 Non-Statutory Stock Option 
         Agreement - Employee/Officer/Director.

99.5     Agouron Pharmaceuticals, Inc. 1996 Non-Statutory Stock Option 
         Agreement - Consultant.


Item 9.  Undertakings.

     (a)     The undersigned Registrant hereby undertakes:

             (1)     To file, during any period in which offers or sales are 
             being made, a post-effective amendment to this Registration 
             Statement:

                                       II-3
[PAGE] 

                     (i)     to include any prospectus required by Section 
                     10(a)(3) of the Securities Act of 1933;

                     (ii)    to reflect in the prospectus any facts or events 
                     arising after the effective date of this Registration 
                     Statement (or the most recent post-effective amendment 
                     hereof) which, individually or in the aggregate, 
                     represent a fundamental change in the 
                     information set forth in this Registration Statement;

                     (iii)   to include any material information with respect 
                     to the plan of distribution not previously disclosed in 
                     this Registration Statement or any material change to 
                     such information in this Registration Statement;

provided, however, that paragraphs (a)(l)(i) and (a)(l)(ii) do not apply if 
the information required to be included in a post-effective amendment by 
those paragraphs is contained in periodic reports filed by the Registrant 
pursuant to Section 13 or Section 15(d) of the Securities Exchange Act of 
1934 that are incorporated by reference in this Registration Statement.

             (2)     That, for the purpose of determining any liability under 
             the Securities Act of 1933, each such post-effective amendment 
             shall be deemed to be a new registration statement relating to 
             the securities offered therein, and the offering of such 
             securities at that time shall be deemed to be the initial bona 
             fide offering thereof. 

             (3)     To remove from Registration by means of a post-effective 
             amendment any of the securities being registered which remain 
             unsold at the termination of the offering.

     (b)     The undersigned Registrant hereby undertakes that, for purposes 
of determining any liability under the Securities Act of 1933, each filing of 
the Registrant's annual report pursuant to Section 13(a) or Section 15(d) of 
the Securities Exchange Act of 1934 (and each filing of the annual report of 
the Plan pursuant to Section 15(d) of the Securities Exchange Act of 1934) 
that is incorporated by reference in this Registration Statement shall be 
deemed to be a new registration statement relating to the securities offered 
therein, and the offering of such securities at that time shall be deemed to 
be the initial bona fide offering thereof.

     (c)     Insofar as indemnification for liabilities arising under the 
Securities Act of 1933 may be permitted to directors, officers and 
controlling persons of the Registrant pursuant to the foregoing provisions, 
or otherwise, the Registrant has been advised that in the opinion of the 
Securities and Exchange Commission such indemnification is against public 
policy as expressed in the Act and is, therefore, unenforceable.  In the 
event that a claim for indemnification against such liabilities (other than 
the payment by the Registrant of expenses incurred or paid by a director, 
officer or controlling person of the Registrant in the successful defense of 
any action, suit or proceeding) is asserted by such director, officer or 
controlling person in connection with the securities being registered, the 
Registrant will, unless in the opinion of its counsel the matter has been 
settled by controlling precedent, submit to a court of appropriate 
jurisdiction the question whether such indemnification by it is against 
public policy as expressed in the Act and will be governed by the final 
adjudication of such issue. 

                                       II-4
[PAGE] 


                                  SIGNATURES

     Pursuant to the requirements of the Securities Act of 1933, the 
Registrant certifies that it has reasonable grounds to believe that it meets 
all of the requirements for filing on Form S-8 and has duly caused this 
Registration Statement to be signed on its behalf by the undersigned, 
thereunto duly authorized, in the City of San Diego, State of California, on 
November 26, 1996.



                                AGOURON PHARMACEUTICALS, INC.



November 26, 1996               By /s/ Peter Johnson
                                   ----------------------------------
                                   Peter Johnson
                                   President, Principal Executive Officer


November 26, 1996               By /s/ Steven S. Cowell
                                   ---------------------------------
                                   Steven S. Cowell
                                   Vice President, Finance, Chief Financial 
                                   Officer and Principal Accounting Officer

                                       II-5
[PAGE] 

                                POWER OF ATTORNEY



     KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears 
below constitutes and appoints Peter Johnson and Gary E. Friedman, or any of 
them, his true and lawful attorney-in-fact and agents, with full power of 
substitution and resubstitution, for him/her and in his/her name, place and 
stead, in any and all capacities, to sign any or all amendments to this 
Registration Statement, and to file the same, with all exhibits thereto, and 
under documents in connection therewith with the Securities and Exchange 
Commission, granting unto said attorney-in-fact and agents full power and 
authority to do and perform each and every act and thing requisite and 
necessary to be done in and about the premises, as fully and to all intents 
and purposes as he/she might or could do in person, hereby ratifying and 
confirming all that said attorneys-in-fact and agents or their substitute or 
substitutes, may lawfully do or cause to be done by virtue hereof.



     Pursuant to the requirements of the Securities Act of 1933, this 
Registration Statement has been signed by the following persons in the 
capacities and on the date indicated.


Signature                   Title                           Date

/s/ Peter Johnson           President, Principal           November 26, 1996
- -------------------------   Executive Officer, and
 Peter Johnson              Director

/s/ Steven S. Cowell        Vice President, Finance, 
- -------------------------   Chief Financial Officer and    November 26, 1996
 Steven S. Cowell           Principal Accounting Officer

/s/ Gary E. Friedman        Vice President and General     November 26, 1996
- -------------------------   Counsel, Secretary and Director
Gary E. Friedman

/s/ John N. Abelson         Director                       November 26, 1996
- ------------------------
John N. Abelson

/s/ Patricia M. Cloherty    Director                       November 26, 1996
- ------------------------
Patricia M. Cloherty

/s/ A.E. Cohen              Director                       November 26, 1996
- -----------------------
A.E. Cohen

/s/ Michael E. Herman       Director                       November 26, 1996
- -----------------------
Michael E. Herman

/s/ Irving S. Johnson       Director                       November 26, 1996
- -----------------------
Irving S. Johnson

/s/Antonie T. Knoppers      Director                       November 26, 1996
- -----------------------
Antonie T. Knoppers

/s/ Melvin I. Simon         Director                       November 26, 1996
- -----------------------
Melvin I. Simon

                                       II-6
[PAGE] 


                                 EXHIBIT INDEX


EXHIBIT                                                                Page

4.1     Restated Articles of Incorporation dated October 20, 1990,
        incorporated by reference to the Company's Form 10-Q 
        for the Quarter ended December 31, 1992.

4.2     Rights Agreement dated as of November 7, 1996, between
        the Company and Chase Mellon Shareholder Services, 
        L.L.C., which includes the Certificate of Designation, 
        Preferences and Rights of Series B Participating Preferred 
        Stock as Exhibit A, the Form of Rights Certificate as 
        Exhibit B and the Form of Summary of Rights as Exhibit C, 
        incorporated by reference to Exhibit 4.4 of the Company's
        current report on Form 8-K dated November 7, 1996.

5       Opinion of Gary E. Friedman, Esq.

23.1    Consent of Price Waterhouse LLP.

23.2    Consent of Gary E. Friedman, Esq. (included in his opinion filed as 
        Exhibit 5).

24      Power of Attorney (contained on signature page of this Registration 
        Statement).

99.1    The Agouron Pharmaceuticals, Inc. 1996 Stock Option Plan.

99.2    Form of Notice of Grant.

99.3    Agouron Pharmaceuticals, Inc. 1996 Incentive Stock Option Agreement.

99.4    Agouron Pharmaceuticals, Inc. 1996 Non-Statutory Stock Option 
        Agreement - Employee/Officer/Director.

99.5    Agouron Pharmaceuticals, Inc. 1996 Non-Statutory Stock Option 
        Agreement - Consultant.

                                       E-1
[PAGE] 






                                                          Exhibit 5

                            [AGOURON LETTERHEAD]


November 26, 1996







AGOURON PHARMACEUTICALS, INC.
10350 North Torrey Pines Road
La Jolla, California  92037



Gentlemen:

In connection with your registration on Form S-8 (the "Registration 
Statement") under the Securities Act of 1933, as amended, of 2,000,000 shares 
of Common Stock of Agouron Pharmaceuticals, Inc. (the "Company"), I advise 
you that, in my opinion, when such shares have been issued and sold pursuant 
to the provisions of the Agouron Pharmaceuticals, Inc. 1996 Stock Option 
Plan, and in accordance with the Registration Statement, such shares will be 
duly authorized, validly issued, fully paid and non-assessable shares of the 
Company's Common Stock.

I hereby consent to the filing of this opinion as an exhibit to the 
Registration Statement.

Sincerely,




Gary E. Friedman, Esq.
Vice President and General Counsel

GEF:hhf




                                                             Exhibit 23.1



                       CONSENT OF INDEPENDENT ACCOUNTANTS







We hereby consent to the incorporation by reference in this Registration 
Statement on Form S-8 of our report dated August 7, 1996 included in the 
Annual Report on Form 10-K of Agouron Pharmaceuticals, Inc. for the year 
ended June 30, 1996.



PRICE WATERHOUSE LLP



San Diego, California
November 26,  1996





                                                               EXHIBIT 99.1


                           AGOURON PHARMACEUTICALS, INC.
                             1996 STOCK OPTION PLAN
               (Adopted by the Board of Directors August 7, 1996)
                 (Approved by the Shareholders November 7, 1996)


1.     Purpose.

     This 1996 Stock Option Plan is intended to encourage stock ownership in 
Agouron Pharmaceuticals, Inc. by the officers, directors, employees and 
consultants of the Company and its affiliates in order to promote their 
interest in the success of the Company and to encourage their continued 
affiliation.  All options granted under this 1996 Stock Option Plan are 
intended to be either (a) Incentive Stock Options or (b) Non-Statutory Stock 
Options.


2.     Definitions.

     As used herein the following definitions shall apply:

     "Act" shall mean the Securities Exchange Act of 1934, as amended from 
time to time.

     "Affiliate" shall mean any corporation defined as a "parent corporation" 
or a "subsidiary corporation" by Code Section 424(e) and (f), respectively.

     "Agreement" shall mean either a 1996 Incentive Stock Option Agreement or 
a 1996 Non-Statutory Stock Option Agreement, embodying the terms of the 
agreement between the Company and the Optionee with respect to Optionee's 
Option.

     "Board" shall mean the Board of Directors of the Company.

     "Code" shall mean the Internal Revenue Code of 1986, as amended from 
time to time.

     "Company" shall mean Agouron Pharmaceuticals, Inc., a California 
corporation.

     "Consultant" shall mean any person who is placed on the Company's 
Consultants List by the Board and who agrees in writing to be included 
thereon.

     "Disability" or "Disabled" shall mean the condition of being "disabled" 
within the meaning of Section 422(c)(6) of the Code or any successor 
provision.

     "Director" shall mean an individual member of the Board.

     "Employee" shall mean any salaried employee of the Company or its 
Affiliates, including those employees who are officers of the Company or its 
Affiliates.

     "ERISA" shall mean the Employee Retirement Income Security Act or the 
rules thereunder, as amended from time to time.

                                       -1-
 [PAGE]

     "Fair Market Value" of Stock on a given date shall mean an amount per 
share as determined by the Board or its delegates by applying any reasonable 
valuation method determined without regard to any restriction other than a 
restriction which, by its terms, will never lapse.  Notwithstanding the 
preceding, if the Stock is traded upon an established stock exchange, then 
the "Fair Market Value" of Stock on a given date per share shall be deemed to 
be the average of the highest and lowest selling price per share of the Stock 
on the principal stock exchange on which the Stock is then trading or, if 
there was no trading of the Stock on that day, on the next preceding day on 
which there was such trading; if the Stock is not traded upon an established 
stock exchange but is quoted on a quotation system, the "Fair Market Value" 
of Stock on a given date shall be deemed to be the mean between the closing 
representative "bid" and "ask" prices per share of the Stock on such date as 
reported by such quotation system or, if there was no trading of the Stock on 
that day, on the next preceding day on which there was such trading.

     "Incentive Stock Option" shall mean an option granted pursuant to the 
Plan which is designated by the Board or its delegates as an "Incentive Stock 
Option" and which qualifies as an incentive stock option under Section 422 of 
the Code or any successor provision.  

     "Non-Statutory Stock Option" shall mean a stock option granted pursuant 
to the Plan which is not an Incentive Stock Option.

     "Option" shall refer to either or both an Incentive Stock Option or Non-
Statutory Stock Option, as the context shall indicate.

     "Optionee" shall mean the recipient of an Incentive Stock Option or a 
Non-Statutory Stock Option. 

     "Option Price" shall mean the price per share of Stock to be paid by the 
Optionee upon exercise of the Option.

     "Option Stock" shall mean the total number of shares of Stock the 
Optionee shall be entitled to purchase pursuant to the Agreement.

     "Plan" shall mean this Agouron Pharmaceuticals, Inc. 1996 Stock Option 
Plan, as amended from time to time.

     "Reporting Person" shall mean an Optionee who is required to file 
statements relating to his or her beneficial ownership of Stock with the SEC 
pursuant to Section 16(a) of the Act.

     "Rule 16b-3" shall mean Rule 16b-3 (as amended from time to time), 
promulgated by the SEC under the Act, and any successor thereto.

     "SEC" shall mean the Securities and Exchange Commission.

     "Stock" shall mean the no par Common Stock of the Company.

                                       -2-
 [PAGE]


3.     Administration.

     The Plan shall be administered by the Board; provided, however, that the 
Board may delegate all or any part of its authority to administer the Plan in 
its entirety or, with respect to any group or groups of persons eligible to 
receive Options hereunder, to such persons or committee as the Board shall in 
its sole discretion determine.  The Board and its delegates may adopt, amend 
and rescind such rules and regulations for carrying out the Plan and 
implementing agreements and take such act as it deems proper.  The 
interpretation, construction and application by the Board or any individuals 
who are delegated authority by the Board to administer the Plan or any of the 
provisions of the Plan or any Option granted thereunder shall be final and 
binding on the Company, all Optionees, their legal representatives, and any 
person who may acquire an Option directly from an Optionee by permitted 
transfer, bequest or inheritance.  Reference to administrative acts by the 
Board in the Plan shall also refer to acts by its delegates, unless the 
context otherwise indicates.  Whether or not the Board has delegated 
administrative authority, the Board has the final power to determine all 
questions of policy or expediency that may arise in administration of the 
Plan.


4.     Eligibility.

     Only Employees are eligible to receive Incentive Stock Options under the 
Plan.  Employees, officers, Directors and Consultants of the Company or its 
Affiliates are eligible to receive Non-Statutory Stock Options under the 
Plan.

     No person shall be eligible to receive an Option for a larger number of 
shares than is recommended for him by the Board.  Any Optionee may hold more 
than one Option (whether Incentive Stock Options, Non-Statutory Stock 
Options, or both), but only on the terms and conditions and subject to the 
restrictions set forth herein.

     Incentive Stock Options granted to an Employee who owns stock at the 
time the Incentive Stock Option is granted, representing more than ten  
percent (10%) of the total combined voting power of all classes of stock of 
the Company and its Affiliates, shall be granted at an Option Price at least 
one hundred ten percent (110%) of the Fair Market Value of the Stock at the 
time the Incentive Stock Option is granted.  In determining ownership of 
Stock by an Employee, the attribution standards set forth in Code Section 
424(d) shall be applicable.

5.     Stock Subject to the Plan.

     Options granted under the Plan shall be for shares of the Company's 
authorized but unissued or re-acquired Stock.  The aggregate number of shares 
of Stock which may be subject to Options pursuant to the Plan shall not 
exceed two million (2,000,000) shares.  The number of shares available shall 
be adjusted as provided in Paragraph 6(j) below.  Stock issued under other 
stock option plans of the Company shall not be counted against the maximum 
number of shares that can be issued under the Plan.

     In the event that any outstanding Option expires or is terminated for 
any reason, the shares of Stock allocable to the unexercised portion of such 
Option may again be subject to an Option under the Plan.

                                       -3-
 [PAGE]

     If an Optionee pays all or part of any Option Price with shares of 
Stock, the number of shares deemed to be issued to the Optionee (and counted 
against the maximum number of shares that can be issued under the Plan) shall 
be the number of shares transferred to the Optionee by the Company, less the 
number of shares transferred by the Optionee to the Company as payment. 
Stock issued on the exercise of an Option which is forfeited in accordance 
with the conditions contained in the grant by the Optionee after issuance 
shall be deemed to have never been issued under the Plan and, accordingly, 
shall not be counted against the maximum number of shares that can be issued 
under the Plan.  Notwithstanding the terms of the previous two sentences, the 
maximum number of shares for which Incentive Stock Options may be issued 
under the Plan shall be two million (2,000,000) shares, subject to adjustment 
as provided under Paragraph 6(j), regardless of the fact that under the terms 
of the preceding sentences, a lesser number of shares is deemed to be issued 
pursuant to the exercise of Incentive Stock Options.


6.     Terms and Conditions of Options.

     The Board or its delegates shall authorize the granting of all Options 
under the Plan with such Options to be evidenced by Incentive Stock Option 
Agreements or Non-Statutory Stock Option Agreements, as the case may be. 
Each Agreement shall be in such form as the Board may approve from time to 
time.  Each Agreement shall comply with and be subject to the following terms 
and conditions:

     (a)     Type of Option; Number of Shares.  Each particular Option 
     Agreement shall state the type of Options to be granted (whether 
     Incentive Stock Options or Non-Statutory Stock Options) and the number 
     of shares to which the Option pertains.  Under no circumstances shall 
     the aggregate Fair Market Value of the Stock (determined as of the time 
     the Option is granted) with respect to which incentive stock options are 
     exercisable for the first time by any Employee during any calendar year 
     (under all incentive stock option plans of the Company and its 
     Affiliates) exceed $100,000.

     (b)     Option Price.  Each particular Option Agreement shall state the 
     Option Price.  The Option Price for an Incentive Stock Option shall not 
     be less than one hundred percent (100%) of the Fair Market Value per 
     share of Stock on the date the Incentive Stock Option is granted.  The 
     Option Price for a Non-Statutory Stock Option shall be the price per 
     share of Stock set by the Board or its delegates.

     (c)     Certificate Legends.  Certificates for shares of Stock issued 
     and delivered to Reporting Persons may be legended, as the Board deems 
     appropriate, if required by the provisions of any applicable rule or 
     regulation.

     (d)     Medium and Time of Payment.  The aggregate Option Price shall be 
     payable upon the exercise of the Option and shall be paid in any 
     combination of: 

             (i)     United States cash currency; 

             (ii)    a cashier's or certified check to the order of the 
             Company; 

             (iii)   a personal check acceptable to the Company; 

                                       -4-
 [PAGE]

             (iv)    to the extent permitted by the Board, shares of Stock of 
             the Company (including previously owned Stock or Stock issuable 
             in connection with the Option exercise), properly endorsed to 
             the Company, whose Fair Market Value on the date of exercise 
             equals the aggregate Option Price of the Option being exercised; 
             or

             (v)     to the extent permitted by the Board, the Optionee's 
             entering into an agreement with the Company, whereby a portion 
             of the Optionee's Options are terminated and where the "built-in 
             gain" on any Options which are terminated as part of such 
             agreement equals the aggregate Option Price of the Option being 
             exercised.  "Built-in gain" means the excess of the aggregate 
             Fair Market Value of any Stock otherwise issuable on exercise of 
             a terminated Option, over the aggregate Option Price otherwise 
             due the Company on such exercise.  

     The Board may permit deemed or constructive transfer of shares in lieu 
     of actual transfer and physical delivery of certificates.  Except to the 
     extent prohibited by applicable law, the Board may take any necessary or 
     appropriate steps in order to facilitate the payment of any such Option 
     Price.  Without limiting the foregoing, the Board may cause the Company 
     to loan the Option Price to the Optionee or to guarantee that any Stock 
     to be issued will be delivered to a broker or lender in order to allow 
     the Optionee to borrow the Option Price.  The Board, in its sole and 
     exclusive discretion, may require satisfaction of any rules or 
     conditions in connection with payment of the Option Price at any 
     particular time, in any particular form, or with the Company's 
     assistance.  If Stock used to pay any Option Price is subject to any 
     prior restrictions imposed in connection with any plan of the Company 
    (including this Plan), an equal number of the shares of Stock acquired on 
     exercise shall be made subject to such prior restrictions in addition to 
     any further restrictions imposed on such Stock by the terms of the 
     Optionee's Agreement or by the Plan.

     (e)     Duration of Options.  Each particular Option Agreement shall 
     state the term of the Option; provided, however, that all Incentive 
     Stock Options granted under this Plan shall expire and not be 
     exercisable after the expiration of ten (10) years from the date 
     granted; provided, further, that any Incentive Stock Option granted to 
     an Employee who owns stock at the time the Incentive Stock Option is 
     granted representing more than ten percent (10%) of the total combined 
     voting power of all classes of stock of the Company and its Affiliates 
     shall expire and not be exercisable after the expiration of five (5) 
     years from the date granted.  Non-Statutory Stock Options shall expire 
     and not be exercisable after the date set by the Board or its delegates 
     in the particular Option Agreement, or on any later date subsequently 
     approved by the Board or its delegates.

     (f)     Exercise of Options.

             (i)     Each particular Option Agreement shall state when the 
             Optionee's right to purchase Stock pursuant to the terms of an 
             Option are exercisable in whole or in part.  Subject to the 
             earlier termination of the right to exercise the Options as 
             provided under this Plan, Options shall be exercisable in whole 
             or in part as the Board, in its sole and exclusive discretion, 
             may provide in the particular Option Agreement, as amended.  The 
             Board may at any time increase the percentage an 

                                       -5-
[PAGE]


             Option is otherwise exercisable under the terms of a particular 
             Option Agreement.  The Board, in its sole and exclusive 
             discretion, may permit the issuance of Stock underlying an 
             Option prior to the date the Option is otherwise exercisable, 
             provided such Stock is subject to repurchase rights which expire 
             pro rata as the Option would otherwise have become exercisable.

             (ii)     If the Optionee does not exercise in any one (1) year 
             period the full number of shares to which he or she is then 
             entitled to exercise, the Optionee may exercise those shares in 
             any subsequent year during the term of the Option.

     (g)     Transfer of Options.  An attempted non-permitted transfer of an 
     Option shall be void.

     (h)     Death of Optionee.  If the Optionee who is an Employee, officer 
     or Director of the Company or its Affiliates dies while in the employ or 
     service of the Company or its Affiliates or within a period of three (3) 
     months after termination of such employment or term of corporate office 
     and before he or she has fully exercised an Option, the Option may be 
     exercised, regardless of the expiration date stated in the particular 
     Option Agreement (to the extent that the Option was exercisable on the 
     date of death and had not previously been exercised), for one (1) year 
     after the date of the Optionee's death.  Such exercise may be made by a 
     personal representative of the Optionee or by any person or persons who 
     shall have acquired the Option directly from the Optionee by bequest or 
     inheritance.  Notwithstanding the foregoing, an Incentive Stock Option 
     may not be exercised after ten (10) years following the date of grant.

     (i)     Termination of Employment or Service Other than Death. Subject 
to the provisions of Paragraph 6(h) above, in the event that an Optionee who 
is an Employee, officer or Director of the Company or its Affiliates shall 
cease to be employed by or perform services for the Company or its Affiliates 
prior to the Option's expiration date, the exercise of Options held by such 
Optionee shall be subject to such limitations on the periods of time during 
which such Options may be exercised as may be specified in the particular 
Option Agreement, as amended, between the Optionee and the Company. 
Notwithstanding the foregoing (and subject to the provisions of Paragraph 
6(h) above), an Optionee who is Disabled on the date of termination of 
employment or term of corporate office may exercise his or her Option, to the 
extent that the Option was exercisable on the date of such termination and 
had not previously been exercised, for one (1) year from the date of such 
termination; provided, however, that an Option may not be exercised after the 
expiration date set forth in the particular Option Agreement, as amended. 
Whether authorized leave of absence or absence for military or governmental 
service shall constitute termination of employment for purposes of the Plan 
shall be determined by the Board in their sole and exclusive discretion.  No 
provision of the Plan shall be construed so as to grant any individual the 
right to remain in the employ or service of the Company for any period of 
specific duration.

     (j)     Recapitalization.  

             (i)     The number of shares issuable under the Plan and the 
             number and amount of the Option Stock and the Option Price of 
             outstanding Options shall be 

                                       -6-
[PAGE]

             proportionately adjusted for any increase or decrease in the 
             number of issued shares of Stock resulting from a subdivision or 
             consolidation of shares, or for the payment of a stock dividend, 
             or any other increase or decrease in the number of such shares 
             effected without receipt of consideration by the Company in 
             order to preclude the dilution or enlargement of benefits under 
             the Plan.  

             (ii)    The Board, in its sole and exclusive discretion, may 
             make such equitable adjustments to the Plan and outstanding 
             Options, as it deems appropriate in order to preclude the 
             dilution or enlargement of benefits under the Plan, upon 
             exchange of all of the outstanding stock of the Company for a 
             different class or series of capital stock or the separation of 
             assets of the Company, including a spin-off or other 
             distribution of stock or property by the Company.  

             (iii)   If the Company shall be the surviving corporation in any 
             merger or consolidation, each outstanding Option shall pertain 
             to and apply to the securities to which a holder of the number 
             of shares of Option Stock would have been entitled.  A 
             dissolution or liquidation of the Company, a merger (other than 
             a merger the principal purpose of which is to change the state 
             of the Company's incorporation) or consolidation in which the 
             Company is not the surviving corporation, a reverse merger in 
             which the Company is the surviving corporation but the Company's 
             Common Stock outstanding immediately preceding the merger is 
             converted by virtue of the merger into other property, or other 
             capital reorganization in which more than fifty percent (50%) of 
             the Company's Common Stock is exchanged (unless the dissolution 
             or liquidation plan, merger or consolidation agreement or 
             capital reorganization corporate documents expressly provide to 
             the contrary) shall cause each outstanding Option to terminate, 
             provided, that each Optionee shall, immediately prior to such 
             event, have the right to exercise his or her Option in whole or 
             in part, unless the Option in connection with such event is 
             either to be assumed by the successor corporation or parent 
             thereof, or to be replaced with a comparable option to purchase 
             shares of the capital stock of the successor corporation or 
             parent thereof, or the Option is to be replaced by a comparable 
             cash incentive program of the successor corporation based on the 
             value of the Option on the date of such event. Notwithstanding 
             the preceding, if, within one (1) year from the date of such 
             event, an Employee's employment is involuntarily terminated, 
             then the Employee's outstanding Options, if any, shall become 
             immediately exercisable.  

             (iv)    All adjustments required by the preceding paragraphs 
             shall be made by the Board, whose determination in that respect 
             shall be final, binding and conclusive, provided, that 
             adjustments shall not be made in a manner that causes an 
             Incentive Stock Option to fail to continue to qualify as an 
             "incentive stock option" within the meaning of Code Section 422.

             (v)     Except as expressly provided in this Paragraph 6(j), an 
             Optionee shall have no rights by reason of any subdivision or 
             consolidation of shares of stock of any class, or the payment of 
             any stock dividend, or any other increase in the number of 
             shares of stock of any class by reason of any dissolution, 
             liquidation, merger, consolidation, reorganization, or 
             separation of assets, and any issue by the 

                                       -7-
[PAGE]

             Company of shares of stock of any class, or securities 
             convertible into shares of stock of any class, shall not affect, 
             and no adjustment by reason thereof shall be made with respect 
             to, the number or amount of the Option Stock or the Option Price 
             of outstanding Options.

             (vi)   The grant or existence of an Option shall not affect in 
             any way the right or power of the Company to make adjustments, 
             reclassifications, reorganizations or changes in its capital or 
             business structure, or to merge, consolidate, dissolve, 
             liquidate or sell, or transfer all or any part of its business 
             or assets.

     (k)     Rights as a Shareholder.  An Optionee shall not have rights as 
a shareholder with respect to any shares until the date of the issuance of a 
stock certificate to him or her for such shares.  No adjustment shall be made 
for dividends (ordinary or extraordinary, whether in cash, securities or 
other property) or distributions or other rights for which the record date is 
prior to the date of issuance of such stock certificate, except as provided 
in Paragraph 6(j) above.

     (l)     Modification, Extension and Renewal of Options.  Subject to the 
terms and conditions of the Plan, the Board may modify (including lowering 
the Option Price or changing Incentive Stock Options into Non-Statutory Stock 
Options), extend or renew outstanding Options granted under the Plan, or 
accept the surrender of outstanding Options under this Plan and/or other 
stock option plans of the Company (to the extent not previously exercised) 
and authorize the granting of new Options in substitution therefor. 
Notwithstanding the foregoing, no modification of an Option shall, without 
the consent of the Optionee, alter or impair any rights or obligations under 
any Option previously granted under the Plan.

     (m)     Investment Purpose.  Each Option under the Plan shall be granted 
on the condition that the purchase of Stock thereunder shall be for 
investment purposes for the Optionee's own account and not with a view to 
resale or distribution.  In the event the Stock subject to such Option is 
registered under the Securities Act of 1933, as amended, or in the event a 
resale of such Stock without such registration would otherwise be 
permissible, such condition shall be inoperative if, in the opinion of 
counsel for the Company, such condition is not required under the Securities 
Act of 1933, or any other applicable law, regulation or rule of any 
governmental agency.

    (n)     Transfer and Exercise of Options.  To the extent required by Code 
Section 422, each Incentive Stock Option shall state that it is not 
transferable or assignable by Optionee otherwise than by will or the laws of 
descent and distribution, and that during an Optionee's lifetime, such 
Incentive Stock Option shall be exercisable only by the Optionee.

    (o)     Other Provisions.  Each Option Agreement may contain such other 
provisions, including without limitation, restrictions upon the exercise or 
transferability of the Option, as the Board may deem advisable.  Any 
Incentive Stock Option Agreement shall contain such limitations and 
restrictions upon the exercise of the Incentive Stock Option as shall be 
necessary in order that such Incentive Stock Option shall be an "incentive 
stock option" as defined in Code Section 422, or to conform to any change in 
the law.

                                       -8-
[PAGE]

     (p)     Withholding Taxes.  When the Company becomes required to collect 
federal and state income and employment taxes in connection with the exercise 
of an Option ("withholding taxes"), the Optionee shall promptly pay to the 
Company the amount of such taxes in cash, unless the Board permits or 
requires payment in another form.  Subject to such conditions as it may 
require, the Board, in its sole discretion, may allow an Optionee to 
reimburse the Company for payment of withholding taxes with shares of Stock. 
If an Optionee is a Reporting Person at the time of exercise and is given an 
election to pay any withholding taxes with Stock, the Board shall have sole 
discretion to approve or disapprove such election.

     (q)     Limitation on Grants.  The following limitation will apply to 
grants of Options under the Plan: no Employee will be granted Options under 
the Plan to receive more than seven hundred fifty thousand (750,000) shares 
of Stock in any one fiscal year.  The limitation set forth in this Paragraph 
6(q) is intended to satisfy the requirements applicable to Options intended 
to qualify as "performance-based compensation" within the meaning of Section 
162(m) of the Code.  In the event that such limitation is not required to 
qualify Options as performance-based compensation, this limitation shall not 
apply under the Plan.


7.     Term of Plan.

     Incentive Stock Options may be granted pursuant to the Plan from time to 
time within a period of ten (10) years from the date the Plan is adopted by 
the Board, or the date the Plan is approved by the shareholders of the 
Company, whichever is earlier.


8.     Amendment of Plan.

     With respect to any shares at the time not subject to Options, the Board 
may from time to time, insofar as permitted by law, suspend or discontinue 
the Plan or revise or amend the Plan in any respect whatsoever, except that, 
without approval of the shareholders, no such revision or amendment shall 
change the number of shares for which Options may be granted under the Plan, 
change the designation of the class of persons eligible to receive Options 
under the Plan, materially increase the benefits accruing to Optionees under 
the Plan, or decrease the price at which Incentive Stock Options may be 
granted.  Furthermore, without the approval of the shareholders, the Plan may 
not, be amended in any manner that will cause Incentive Stock Options issued 
under it to fail to meet the requirements of "incentive stock options" as 
defined in Code Section 422.  The Board may amend the Plan from time to time 
to the extent necessary to comply with any applicable law,  rule or other 
regulatory requirement.


9.     Application of Funds.

     The proceeds received by the Company from the sale of Stock pursuant to 
the exercise of an Option will be used for general corporate purposes.

                                       -9-
[PAGE]


10.     No Obligation to Exercise Option.

     The granting of an Option shall impose no obligation upon the Optionee 
to exercise such Option.


11.     Indemnification.

     In addition to such other rights of indemnification as they may have as 
Directors, Employees or agents of the Company, the Directors, or any 
individuals who are delegated authority by the Board to administer the Plan, 
shall be indemnified by the Company against:  (i) their reasonable expenses, 
including attorneys' fees actually and necessarily incurred in connection 
with the defense of any action, suit or proceeding, or in connection with any 
appeal therein, to which they or any of them may be a party by reason of any 
action taken or failure to act under or in connection with the Plan or any 
Option granted thereunder; and (ii) against all amounts paid by them in 
settlement thereof (provided such settlement is approved by independent legal 
counsel selected by the Company), or paid by them in satisfaction of a 
judgment in any such action, suit or proceeding, except in actions to matters 
as to which it shall be adjudged in such action, suit or proceeding that such 
Director or individual is liable for negligence or misconduct in the 
performance of his duties; this indemnification is expressly conditioned upon 
the indemnified party, within ninety (90) days after institution of any such 
action, suit or proceeding, offering the Company in writing the opportunity, 
at its own expense, to handle and defend the same.


12.     Approval of Shareholders.

     The portions of the Plan dealing with Incentive Stock Options shall not 
take effect unless approved by the shareholders of the Company's preferred 
 (if any) and Common Stock, which approval must occur within a period 
commencing twelve (12) months before and ending twelve (12) months after the 
date the Plan is adopted by the Board.  Nothing in the Plan shall be 
construed to limit the authority of the Company to exercise its corporate 
rights and powers, including the right of the Company to grant non-statutory 
options for proper corporate purposes.



     Adopted by the Board of Directors on August 7, 1996.



AGOURON PHARMACEUTICALS, INC.



By:_______________________________ 
   Peter Johnson, President & CEO


                                       -10-
[PAGE]






                                                             EXHIBIT 99.2

Notice of Grant of Stock Option

                                            Agouron Pharmaceuticals, Inc.
                                            10350 North Torrey Pines Road
                                            La Jolla, California 92037
                                            (619) 622-8000

[Insert Grantee's Name & Address]
_____________________________
_____________________________
_____________________________
_____________________________

You have been granted an option ("Option") to buy Agouron Pharmaceuticals, 
Inc. ("Agouron") common stock as follows:

           Stock Option Grant No.                    _________
           Date of Grant                             _________
           Stock Option Agreement                    _________ (Attachment 1)
           Option Price per Share                    _________
           Total Number of Shares Granted            _________
           Expiration Date/Time                      _________ 12:00 p.m.

                                 VESTING SCHEDULE

                                                            Cumulative Amount
                                     Stock Available       of Stock Available
              On or After              For Exercise            For Exercise
               _________                _________                _________
               _________                _________                _________
               _________                _________                _________
               _________                _________                   TOTAL

By your signature and Agouron's signature below, you and Agouron agree that 
this Option is granted under and governed by the terms and conditions of 
Agouron's 1996 Stock Option Agreement (Attachment 1) and the 1996 Stock 
Option Plan (Attachment 2), which are attachments hereto and are made a part 
hereof by this reference.

Attachments:

1.     1996 Stock Option Agreement (Form Dated November 7, 1996).
2.     1996 Stock Option Plan (Adopted by the Shareholders November 7, 1996).
3.     Prospectus Information Memorandum, which describes, among other 
          things, the federal income tax consequences of exercising your 
          options.

Additionally, if you have not received a copy of Agouron's latest annual 
report, please contact the Investor Relations Department, or you may review 
the latest annual report information over the Internet at Agouron's Web Site 
address:  
                              http://www.agouron.com

AGOURON PHARMACEUTICALS, INC.                   OPTIONEE


By: ______________________________              __________________________ 
    [Name of Corporate Officer]                 [Name of Grantee]



                                                               EXHIBIT 99.3

                                ATTACHMENT NO. 1 
                                        TO 
                          NOTICE OF GRANT STOCK OPTION

                        AGOURON PHARMACEUTICALS, INC.
                         (a California Corporation)

                   1996 INCENTIVE STOCK OPTION AGREEMENT


     This Option Agreement is entered into between Agouron Pharmaceuticals, 
Inc., a California corporation and the Optionee whose name appears on the 
Notice of Grant of Stock Option to which this Agreement is an attachment.


1.     Recitals.

     1.01     The Board of Directors of the Company or its duly authorized 
delegates authorized the granting of this Option to Optionee who is an 
Employee of the Company or its Affiliates pursuant to the Agouron 
Pharmaceuticals, Inc. 1996 Stock Option Plan.

     1.02     This Option Agreement is intended to constitute an "incentive 
stock option" within the meaning of Section 422 of Internal Revenue Code of 
1986, as amended from time to time.


2.     Definitions.

     In addition to those words and phrases defined above and unless 
otherwise required by the context in which they appear, words and phrases 
having their initial letters capitalized shall have the following meanings:

     2.01     Act.  "Act" shall mean the Securities Exchange Act of 1934, as 
amended from time to time.

     2.02     Affiliate.  "Affiliate" shall mean any corporation defined as a 
"parent corporation" or a "subsidiary corporation" by Code Section 424(e) and 
(f), respectively.

     2.03     Agreement.  "Agreement" shall mean this 1996 Incentive Stock 
Option Agreement (including any schedules, attachments, documents 
incorporated by reference, or modifications agreed to in writing by the 
Company and Optionee) which sets forth the Optionee's and the Company's 
rights and obligations with respect to the Option granted Optionee by the 
Board or its duly authorized delegates as described on the Notice of Grant.

     2.04     Board.  "Board" shall mean the Board of Directors of the 
Company.

     2.05     Code.  "Code" shall mean the Internal Revenue Code of 1986, as 
amended from time to time.


1996 ISO Form Dated:  November 7, 1996                               1 of 9

[PAGE] 

     2.06     Company.  "Company" shall mean Agouron Pharmaceuticals, Inc., a 
California corporation, and any successors or assigns.

     2.07     Date of Grant.  "Date of Grant" shall mean the Date of Grant 
set forth on the Notice of Grant.

     2.08     Disability.  "Disability" or "Disabled" shall mean the 
condition of being "disabled" within the meaning of Section 422(c)(6) of the 
Code or any successor provision. 

     2.09     Employee.  "Employee" shall mean any salaried employee of the 
Company or its Affiliates, including those employees who are officers of the 
Company or its Affiliates.

     2.10     Expiration Date.  "Expiration Date" shall mean the Expiration 
Date set forth on the Notice of Grant.

     2.11     Fair Market Value.  "Fair Market Value" of Stock on a given 
date shall mean an amount per share, as determined by the Board or its 
delegates by applying any reasonable valuation method determined without 
regard to any restriction other than a restriction which, by its terms, will 
never lapse.  Notwithstanding the preceding, if the Stock is traded upon an 
established stock exchange, then the "Fair Market Value" of Stock on a given 
date per share shall be deemed to be the average of the highest and lowest 
selling price per share of the Stock on the principal stock exchange on which 
the Stock is then trading or, if there was no trading of the Stock on that 
day, on the next preceding day on which there was such trading; if the Stock 
is not traded upon an established stock exchange but is quoted on a quotation 
system, the "Fair Market Value" of Stock on a given date shall be deemed to 
be the mean between the closing representative "bid" and "ask" prices per 
share of the Stock on such date as reported by such quotation system or, if 
there was no trading of the Stock on that day, on the next preceding day on 
which there was such trading.

     2.12     Notice of Grant of Stock Option.  "Notice of Grant of Stock 
Option" or "Notice of Grant" shall mean the Notice of Grant executed by the 
Company and the Optionee to which this Agreement is an attachment.

     2.13     Option.  "Option" shall mean the right of Optionee to purchase 
the number of shares of Stock set forth on the Notice of Grant in accordance 
with the terms and conditions of this Agreement.

     2.14     Optionee.  "Optionee" shall mean the person whose name is set 
forth on the Notice of Grant.

     2.15     Option Price.  "Option Price" shall mean the price per share of 
Stock to be paid by the Optionee upon exercise of the Option, which amount is 
set forth on the Notice of Grant.


1996 ISO Form Dated:  November 7, 1996                               2 of 9

[PAGE] 

     2.16     Option Stock.  "Option Stock" shall mean the total number of 
shares of Stock the Optionee shall be entitled to purchase pursuant to this 
Agreement, which number of shares is set forth on the Notice of Grant.

     2.17     Plan.  "Plan" shall mean the 1996 Agouron Pharmaceuticals, Inc. 
Stock Option Plan, as amended from time to time.

     2.18     Reporting Person.  "Reporting Person" shall mean an Optionee 
who is required to file statements relating to his or her beneficial 
ownership of Stock with the SEC pursuant to Section 16(a) of the Act.

     2.19     Rule 16b-3.  "Rule 16b-3" shall mean Rule 16b-3 (as amended 
from time to time) promulgated by the SEC under the Act, and any successor 
thereto.

     2.20     SEC.  "SEC" shall mean the Securities and Exchange Commission.

     2.21     Stock.  "Stock" shall mean the no par common stock of the 
Company.

     2.22     Vesting.  "Vesting" shall mean the date(s) when all or a portion 
of the Option Stock becomes available for exercise.

     2.23     Vesting Schedule.  "Vesting Schedule" shall mean the Vesting 
Schedule set forth on the Notice of Grant which indicates on what dates all or 
a portion of the Option Stock becomes available for exercise.


3.     Option.

     3.01     Grant.  The Company hereby grants to Optionee an Option to 
purchase all or any part of the Option Stock on the terms and conditions set 
forth in this Agreement.  The Date of Grant shall be the Date of Grant set 
forth on the Notice of Grant.

     3.02     Purchase Price.  The purchase price per share of Stock to be 
paid upon the exercise of this Option shall be the Option Price set forth on 
the Notice of Grant.  This Option Price is deemed by the Board or its 
delegatees to be not less than the Fair Market Value of the Stock on the Date 
of Grant.

     3.03     Restrictions on Transfer.  This Option shall not be 
transferable by Optionee, other than by will or the laws of descent and 
distribution, and may be exercised during Optionee's lifetime only by 
Optionee; provided, however, that this Option may be transferred to a trust 
for the benefit of the Optionee or members of his or her immediate family, 
provided that such transfer does not violate the requirements of Rule 16b-3 
and Code Section 422.  Upon any attempt to sell, assign, encumber or 
otherwise transfer this Option in violation of this Agreement, or upon the 
levy of any attachment or similar process upon this Option, this Option shall 
immediately become null and void.


1996 ISO Form Dated:  November 7, 1996                               3 of 9

[PAGE] 

     3.04     Modifications of Rights.  As set forth in Paragraph 6(l) of the 
Plan, the Board may modify (including, lowering the Option Price or 
converting this Option, which is an incentive stock option, into a non-
statutory stock option), extend or renew this Option (to the extent not 
previously exercised), or accept the surrender of this Option (to the extent 
not previously exercised) and authorize the granting of new Stock options in 
substitution therefor; provided, however, that no modification of this Option 
shall, without the consent of the Optionee, alter or impair any existing 
rights or obligations of Optionee under this Option.

     3.05     Changes in Company's Equity Structure; Recapitalization of 
Company.  Upon the occurrence of the capital and/or recapitalization 
transactions described in Paragraph 6(j) of the Plan, this Option (to the 
extent not previously exercised) shall be adjusted or modified as provided in 
Paragraph 6(j) of the Plan.  Notwithstanding any provision of this Agreement, 
the Company reserves the right to:

             (a)     make or enter into any adjustments, reclassifications, 
                     reorganizations or changes of its capital or business 
                     structure;

             (b)     merge or consolidate with other entities; or

             (c)     dissolve, liquidate or sell, or transfer all or any part 
                     of its business or assets.

     3.06     Shareholder's Rights.  Optionee shall have no rights as a 
shareholder with respect to any shares Optionee is entitled to purchase under 
this Option until the date of the issuance of a certificate for such shares.  
No adjustment shall be made for dividends (ordinary or extraordinary, whether 
in cash, securities or other property) or distributions or other rights for 
which the record date is prior to the date of issuance of such certificate, 
except as provided in this Agreement or in the Plan.


4.     Employment Conditions.

     4.01     Employment Status.  Optionee shall be considered to be in the 
employment of the Company as long as Optionee remains an Employee of the 
Company or its Affiliates.  The Board exclusively shall determine:

              (a)     whether or when there has been a termination of 
                      Optionee's employment;

              (b)     if there has been a failure to comply with Optionee's 
                      covenant not to compete obligations; and 

              (c)     the cause of such termination, 

which determination shall be final.

     4.02     Covenant Not to Compete.  Unless otherwise permitted in 
writing, Optionee, who is an Employee of the Company or its Affiliates, shall 
devote his or her entire time, energy and 


1996 ISO Form Dated:  November 7, 1996                               4 of 9

[PAGE] 

skill to the service of the Company or its Affiliates, subject to vacation, 
sick leave and other approved absences.  Failure of Optionee to comply with 
the covenant not to compete obligations stated above within thirty (30) days 
of written notice of such failure shall cause, on the thirtieth (30th) day 
after such written notice, the cancellation of Optionee's right to purchase 
Option Stock (to the extent not previously exercised) without further action 
by the Company.

     4.03     Termination for Cause.  Unless otherwise agreed to by the 
Board, if Optionee's employment is terminated for cause, the right of 
Optionee to purchase Option Stock shall only be exercisable by Optionee for a 
period of thirty (30) days after the date of such termination.


5.     Exercise.

     5.01     Exercise Amounts.  Subject to the earlier termination of the 
right to exercise this Option as provided under this Agreement, including 
Paragraphs 4.02 and 4.03 above, the Optionee shall be entitled to exercise 
the amounts of Option Stock, in whole or in part, as set forth in the Vesting 
Schedule on the Notice of Grant.

     5.02     Additional Adjustments.  Notwithstanding the terms of Paragraph 
5.01 of this Agreement, the Board in its sole and exclusive discretion may 
provide for conditions for the exercise of this Option and/or modify the 
Vesting Schedule set forth on the Notice of Grant; provided, however, the 
Board may only modify the conditions for the exercise of this Option and/or 
modify the Vesting Schedule to provide for a more restrictive Vesting 
Schedule with the consent of Optionee, if such modification alters or impairs 
any existing rights or obligations of Optionee under this Option.  

     5.03     Cumulative Exercise Rights.  If the Optionee does not exercise 
in any one year period the full number of shares to which he or she is then 
entitled to exercise, Optionee may exercise those shares in any subsequent 
year prior to the Expiration Date of this Option as set forth on the Notice 
of Grant, or such later date subsequently approved by the Board or its 
delegates.

     5.04     Expiration of Exercise Rights.  Subject to the provisions of 
Paragraph 5.08, in no event shall this Option be exercisable after the 
Expiration Date or such later date subsequently approved by the Board or its 
delegates; provided, however, that this Option shall expire and not be 
exercisable after the expiration of ten (10) years from the Date of Grant.

     5.05     Fractional Shares.  This Option shall not be exercisable with 
respect to any fractional shares of the Stock.

     5.06     Exercise Procedure.  This Option shall be exercised by the 
giving of written notice of exercise to the Company which specifies the 
number of shares of Stock to be purchased, accompanied by payment (in 
accordance with the terms of Paragraph 6(d) of the Plan) of the aggregate 
Option Price for the shares of Stock being purchased, such payment to be made 
in any combination of:


1996 ISO Form Dated:  November 7, 1996                               5 of 9

[PAGE] 


              (a)     United States cash currency;

              (b)     a cashier's or certified check to the order of the 
                      Company;

              (c)     a personal check acceptable to the Company;

              (d)     to the extent permitted by the Board, shares of Stock 
                      (including previously owned Stock or Stock issuable in 
                      connection with the Option exercise), properly endorsed 
                      to the Company, whose Fair Market Value on the date of 
                      exercise equals the aggregate Option Price of the 
                      Option being exercised; or

              (e)     to the extent agreed to by the Board, the Optionee's 
                      entering into an agreement with the Company whereby a 
                      portion of the Optionee's Options are terminated and 
                      where the "built-in gain" on any Options which are 
                      terminated as part of such agreement equals the 
                      aggregate Option Price of the Option being exercised. 
                      "Built-in gain" means the excess of the aggregate Fair 
                      Market Value of any Stock otherwise issuable on 
                      exercise of a terminated Option, over the aggregate 
                      Option Price otherwise due the Company on such 
                      exercise; 

provided, however, that the form of payment which Optionee selects shall be 
permissible under the Code Section 422.  The Board (in accordance with the 
terms of Paragraph 6(d) of the Plan) may provide such assistance to the 
Optionee to facilitate the exercise of this Option as it deems appropriate; 
provided, however, that the Board, as a prerequisite to providing such 
assistance, may require satisfaction of any rules or conditions it deems 
appropriate.  Shares of Stock used to pay the Option Price shall be valued at 
their Fair Market Value on the date of exercise.  The Optionee's notice of 
exercise shall also be accompanied by payment (in accordance with the terms 
of Paragraph 6(p) of the Plan) of the amount of federal and state income and 
employment taxes that the Company is required to collect from Optionee 
because of the exercise of the Option.

     5.07     Exercise During Life.  Subject to the provisions of Paragraphs 
4.02, 4.03, 5.04 and 5.08, during Optionee's lifetime, this Option shall be 
exercisable only by Optionee either:

              (a)     while Optionee is employed by the Company or its 
                      Affiliates;

              (b)     within three (3) months after the date on which 
                      Optionee's employment terminates for reasons other than 
                      "termination for cause" as provided in Paragraph 4.03 
                      of this Agreement; or

              (c)     within one (1) year after the date on which the 
                      Optionee's employment terminates due to a Disability;

provided, however, that in no event shall the period of exercise be extended 
beyond the Expiration Date.  Unless the Board or its delegates otherwise 
agree, if Optionee is entitled to purchase shares of Stock after the 
termination of Optionee's employment, the number of shares of Stock Optionee 


1996 ISO Form Dated:  November 7, 1996                               6 of 9

[PAGE] 

may so purchase shall be limited to the number of shares of Stock Optionee 
was entitled to purchase as of such date of termination.

     5.08     Exercise After Death.  If Optionee dies while employed by or 
while serving as an officer or director of the Company or its Affiliates or 
within a period of three (3) months after the date such employment 
terminates, but prior to the complete exercise of this Option, the Option may 
be exercised within one (1) year from the date of Optionee's death, but:

              (a)     only by a personal representative of Optionee, or by 
                      any person or persons who shall have acquired the 
                      Option directly from the Optionee by bequest or 
                      inheritance; and

              (b)     only to the extent that the Option was exercisable on 
                      the date of death and had not previously been 
                      exercised.

     5.09     Consultancy to the Company or Service as a Corporate Officer 
After Termination of Employment.  If Optionee acts as a consultant or 
corporate officer for the Company or its Affiliates after the termination of 
his or her employment, then Optionee shall not be deemed to have terminated 
his or her employment for the Company or its Affiliates for the purposes of 
Paragraphs 5.07 and 5.08 of this Agreement until Optionee ceases to be a 
consultant or corporate officer for the Company or its Affiliates, provided 
Optionee does not violate any covenant not to compete obligations contained 
in his or her employment or consulting agreement with the Company or its 
Affiliates.  Notwithstanding Optionee not being deemed to have terminated his 
or her employment for the Company or its Affiliates pursuant to the terms of 
the preceding sentence, this Option, which is an incentive stock option, 
shall automatically convert into a non-statutory stock option three (3) 
months after the date on which Optionee actually terminates his or her 
employment with the Company or its Affiliates (one (1) year if the Optionee 
is Disabled on the date of termination).

     5.10     Exercise of Option Prior to Vesting.  The Board, in its sole 
and exclusive discretion, may permit the Optionee to exercise this Option 
prior to the date this Option is otherwise exercisable, provided the Stock 
issued on such exercise is subject to repurchase rights which expire pro rata 
as the Option would otherwise have become exercisable.

     5.11     Non-Sequential Exercise Permitted.  Subject to the exercise 
limitations set forth herein, this Option shall be exercisable 
notwithstanding the fact that there is an outstanding incentive stock option 
or non-statutory stock option for the purchase of Stock of the Company which 
was granted before this Option was granted, and no subsequently-granted 
incentive stock option shall fail to be exercisable solely because this Option 
remains outstanding.

     5.12     Legends.  Certificates for shares of Stock acquired upon 
exercise of this Option may contain such legends and transfer restrictions as 
the Company shall deem reasonably necessary or desirable to:  


1996 ISO Form Dated:  November 7, 1996                               7 of 9

[PAGE] 


             (a)     assure the satisfaction of any liability that the 
                     Company may or will have incurred for withholding of any 
                     federal and state income and employment taxes; 

             (b)     facilitate compliance by the Company with any federal or 
                     state laws or regulations, including, without 
                     limitation, legends restricting transfer of the Stock 
                     until there has been compliance with federal and state 
                     securities laws; 

             (c)     assure notice of the Company's repurchase rights under 
                     Paragraph 5.10 of this Agreement; or 

             (d)     assure notice of such other restrictions as may be 
                     imposed on the Stock under the terms of this Agreement.


6.     Conflict Between Plan and Agreement.

     This Agreement, including the Option and Optionee's rights hereunder, is 
subject to and governed by the Plan.  Any conflict between the terms and 
provisions of this Agreement and the terms and provisions of the Plan shall 
be governed by the terms and provisions of the Plan.


7.     Investment Intent.

     This Option is granted on the condition that Optionee's purchase of 
Stock shall be for investment purposes for Optionee's own account and not 
with a view to resale or distribution.  The Company shall not, upon the 
exercise of this Option, be required to issue or deliver shares of Stock or 
certificates therefor if, in the opinion of counsel for the Company, such 
issuance or delivery would be in violation of, or would not comply with, any 
applicable state or federal securities law, regulation or rule.


8.     Notices.

     8.01     In Writing.  All notices, demands, requests, declarations, 
service of process, or other communications permitted or required under this 
Agreement or applicable law shall be in writing.

     8.02     Delivery.  All such communications may be served personally or 
may be sent by registered or certified mail, return receipt requested, 
postage prepaid and addressed to either Optionee or the Company at the 
addresses appearing at the top of the Notice of Grant, or at such other 
address as either party shall have communicated to the other pursuant to this 
Paragraph 8.02.  All such communications shall be deemed effectively 
delivered upon personal service or three (3) days after deposit in the United 
States Mail.



1996 ISO Form Dated:  November 7, 1996                               8 of 9

[PAGE] 


9.     Miscellaneous.

     9.01     Successors and Assigns.  Except as otherwise provided in this 
Agreement, this Agreement shall inure to the benefit of only the Company, 
Optionee and their respective successors or assigns.

     9.02     Status.  Nothing contained in this Agreement shall be construed 
as giving Optionee any right to be retained as an Employee, officer or 
director of the Company.

     9.03     Severability.  If any provision or provisions of this Agreement 
are adjudged to be, for any reason, unenforceable, illegal or void, the 
remainder of the provisions shall remain in full force and effect.

     9.04     Integration.  This Agreement and the Notice of Grant to which 
this Agreement is an attachment constitute the entire understanding of the 
parties concerning this Option.  Except as otherwise provided, any changes, 
modifications, variations, or subordinations pertaining to this Agreement and 
the Notice of Grant are invalid, unless stated in writing and executed by the 
Company and Optionee.

     9.05     Governing Law.  This Agreement and the Option granted hereby 
shall be governed by the laws of the State of California.

     9.06     Attorneys' Fees.  If either party brings an action or seeks to 
enforce or interpret any of the terms or provisions of this Agreement, the 
prevailing party shall be entitled to recover its reasonable attorneys' fees 
and costs, in addition to any other remedy it may be awarded.

     9.07     Counterparts.  This Agreement may be executed in counterparts, 
and the counterparts shall constitute the whole instrument.

     9.08     Titles for Convenience; Gender; and Plurals.  Titles of 
articles and paragraph headings are for convenience only and shall not affect 
the construction or interpretation of this Agreement, or any portion thereof.  
Whenever required by the context hereof, the singular shall include the 
plural, and vice versa; the masculine gender shall include the feminine and 
neuter, and vice versa.


1996 ISO Form Dated:  November 7, 1996                               9 of 9

[PAGE] 







                                                              EXHIBIT 99.4

                                ATTACHMENT NO. 1
                                       TO
                        NOTICE OF GRANT OF STOCK OPTION

                          AGOURON PHARMACEUTICALS, INC.
                          (a California Corporation)

                 1996 NON-STATUTORY STOCK OPTION AGREEMENT
                                     FOR
                    EMPLOYEES, OFFICERS AND DIRECTORS


     This Option Agreement is entered into between Agouron Pharmaceuticals, 
Inc., a California corporation and the Optionee whose name appears on the 
Notice of Grant of Stock Option to which this Agreement is an attachment.


1.     Recitals.

     1.01     The Board of Directors of the Company or its duly authorized 
delegates authorized the granting of this Option to Optionee pursuant to the 
Agouron Pharmaceuticals, Inc. 1996 Stock Option Plan.

     1.02     This Option Agreement is intended to constitute a non-statutory 
stock option, meaning an option which is not an "incentive stock option" 
within the meaning of Section 422 of Internal Revenue Code of 1986, as 
amended from time to time.


2.     Definitions.

     In addition to those words and phrases defined above and unless 
otherwise required by the context in which they appear, words and phrases 
having their initial letters capitalized shall have the following meanings:

     2.01     Act.  "Act" shall mean the Securities Exchange Act of 1934, as 
amended from time to time.

     2.02     Affiliate.  "Affiliate" shall mean any corporation defined as a 
"parent corporation" or a "subsidiary corporation" by Code Section 424(e) and 
(f), respectively.

     2.03     Agreement.  "Agreement" shall mean this 1996 Non-Statutory 
Stock Option Agreement (including any schedules, attachments, documents 
incorporated by reference, or modifications agreed to in writing by the 
Company and Optionee) which sets forth the Optionee's and the Company's rights 
and obligations with respect to the Option granted Optionee by the Board or 
its duly authorized delegates as described on the Notice of Grant.

     2.04     Board.  "Board" shall mean the Board of Directors of the 
Company.

1996 NS Form Dated:  November 7, 1996                              1 of 9

[PAGE]

     2.05     Code.  "Code" shall mean the Internal Revenue Code of 1986, as 
amended from time to time.

     2.06     Company.  "Company" shall mean Agouron Pharmaceuticals, Inc., a 
California corporation, and any successors or assigns.

     2.07     Date of Grant.  "Date of Grant" shall mean the Date of Grant 
set forth on the Notice of Grant.

     2.08     Disability.  "Disability" or "Disabled" shall mean the 
condition of being "disabled" within the meaning of Section 422(c)(6) of the 
Code or any successor provision. 

     2.09     Employee.  "Employee" shall mean any salaried employee of the 
Company or its Affiliates, including those employees who are officers of the 
Company or its Affiliates.

     2.10     Expiration Date.  "Expiration Date" shall mean the Expiration 
Date set forth on the Notice of Grant.

     2.11     Fair Market Value.  "Fair Market Value" of Stock on a given 
date shall mean an amount per share, as determined by the Board or its 
delegates by applying any reasonable valuation method determined without 
regard to any restriction other than a restriction which, by its terms, will 
never lapse.  Notwithstanding the preceding, if the Stock is traded upon an 
established stock exchange, then the "Fair Market Value" of Stock on a given 
date per share shall be deemed to be the average of the highest and lowest 
selling price per share of the Stock on the principal stock exchange on which 
the Stock is then trading or, if there was no trading of the Stock on that 
day, on the next preceding day on which there was such trading; if the Stock 
is not traded upon an established stock exchange but is quoted on a quotation 
system, the "Fair Market Value" of Stock on a given date shall be deemed to be 
the mean between the closing representative "bid" and "ask" prices per 
share of the Stock on such date as reported by such quotation system or, if 
there was no trading of the Stock on that day, on the next preceding day on 
which there was such trading.

     2.12     Notice of Grant of Stock Option.  "Notice of Grant of Stock 
Option" or "Notice of Grant" shall mean the Notice of Grant executed by the 
Company and the Optionee to which this Agreement is an attachment.

     2.13     Option.  "Option" shall mean the right of Optionee to purchase 
the number of shares of Stock set forth on the Notice of Grant in accordance 
with the terms and conditions of this Agreement.

     2.14     Optionee.  "Optionee" shall mean the person whose name is set 
forth on the Notice of Grant.

     2.15     Option Price.  "Option Price" shall mean the price per share of 
Stock to be paid by the Optionee upon exercise of the Option, which amount is 
set forth on the Notice of Grant.

1996 NS Form Dated:  November 7, 1996                              2 of 9

[PAGE]

     2.16     Option Stock.  "Option Stock" shall mean the total number of 
shares of Stock the Optionee shall be entitled to purchase pursuant to this 
Agreement, which number of shares is set forth on the Notice of Grant.

     2.17     Plan.  "Plan" shall mean the 1996 Agouron Pharmaceuticals, Inc. 
Stock Option Plan, as amended from time to time.

     2.18     Reporting Person.  "Reporting Person" shall mean an Optionee 
who is required to file statements relating to his or her beneficial 
ownership of Stock with the SEC pursuant to Section 16(a) of the Act.

     2.19     Rule 16b-3.  "Rule 16b-3" shall mean Rule 16b-3 (as amended 
from time to time) promulgated by the SEC under the Act, and any successor 
thereto.

     2.20     SEC.  "SEC" shall mean the Securities and Exchange Commission.

     2.21     Stock.  "Stock" shall mean the no par common stock of the 
Company.

     2.22     Vesting.  "Vesting" shall mean the date(s) when all or a 
portion of the Option Stock becomes available for exercise.

     2.23     Vesting Schedule.  "Vesting Schedule" shall mean the Vesting 
Schedule set forth on the Notice of Grant which indicates on what dates all 
or a portion of the Option Stock becomes available for exercise.


3.     Option.

     3.01     Grant.  The Company hereby grants to Optionee an Option to 
purchase all or any part of the Option Stock on the terms and conditions set 
forth in this Agreement.  The Date of Grant shall be the Date of Grant set 
forth on the Notice of Grant.

     3.02     Purchase Price.  The purchase price per share of Stock to be 
paid upon the exercise of this Option shall be the Option Price set forth on 
the Notice of Grant.

     3.03     Restrictions on Transfer.  This Option may be transferred to a 
trust for the benefit of the Optionee or members of his or her immediate 
family.  Upon any attempt to sell, assign, encumber or otherwise transfer this 
Option in violation of this Agreement, or upon the levy of any attachment 
or similar process upon this Option, this Option shall immediately become 
null and void.

     3.04     Modifications of Rights.  As set forth in Paragraph 6(l) of the 
Plan, the Board may modify (including, lowering the Option Price), extend or 
renew this Option (to the extent not previously exercised), or accept the 
surrender of this Option (to the extent not previously exercised) and 
authorize the granting of a new Stock option in substitution therefor; 
provided, however, that no modification of this Option shall, without the 
consent of the Optionee, alter or impair any existing rights or obligations 
of Optionee under this Option.

1996 NS Form Dated:  November 7, 1996                              3 of 9

[PAGE]

     3.05     Changes in Company's Equity Structure; Recapitalization of 
Company.  Upon the occurrence of the capital and/or recapitalization 
transactions described in Paragraph 6(j) of the Plan, this Option (to the 
extent not previously exercised) shall be adjusted or modified as provided in 
Paragraph 6(j) of the Plan.  Notwithstanding any provision of this Agreement, 
the Company reserves the right to:

              (a)     make or enter into any adjustments, reclassifications, 
                      reorganizations or changes of its capital or business 
                      structure;

              (b)     merge or consolidate with other entities; or

              (c)     dissolve, liquidate or sell, or transfer all or any 
                      part of its business or assets.

     3.06     Shareholder's Rights.  Optionee shall have no rights as a 
shareholder with respect to any shares Optionee is entitled to purchase under 
this Option until the date of the issuance of a stock certificate for such 
shares.  No adjustment shall be made for dividends (ordinary or 
extraordinary, whether in cash, securities or other property) or 
distributions or other rights for which the record date is prior to the date 
of issuance of such certificate, except as provided in this Agreement or in 
the Plan.


4.     Employment Conditions.

     4.01     Employment Status.  Optionee shall be considered to be in the 
employment of the Company as long as Optionee remains an Employee of the 
Company or its Affiliates.  The Board exclusively shall determine: 

              (a)     whether or when there has been a termination of 
                      Optionee's employment or term of corporate office;

              (b)     if there has been a failure to comply with Optionee's 
                      covenant not to compete obligations; and 

              (c)     the cause of such termination, 

which determination shall be final.

     4.02     Covenant Not to Compete.  Unless otherwise permitted in 
writing, Optionee, who is an Employee of the Company or its Affiliates, shall 
devote his or her entire time, energy and skill to the service of the Company 
or its Affiliates, subject to vacation, sick leave and other approved 
absences.  Failure of Optionee to comply with the covenant not to compete 
obligations stated above within thirty (30) days of written notice of such 
failure shall cause, on the thirtieth (30th) day after such written notice, 
the cancellation of Optionee's right to purchase Option Stock (to the extent 
not previously exercised) without further action by the Company.  The 
restriction contained in this Paragraph 4.02 shall only apply to Employees, 
and not to officers or directors who are not Employees or consultants for the 
Company.

1996 NS Form Dated:  November 7, 1996                              4 of 9

[PAGE]

     4.03     Termination for Cause.  Unless otherwise agreed to by the 
Board, if Optionee's employment or his or her position as an officer or 
director of the Company or its Affiliates is terminated for cause, the right 
of Optionee to purchase Option Stock shall only be exercisable for a period 
of thirty (30) days after the date of such termination.


5.     Exercise.

     5.01     Exercise Amounts.  Subject to the earlier termination of the 
right to exercise this Option as provided under this Agreement, including 
Paragraphs 4.02 and 4.03 above, the Optionee shall be entitled to exercise 
the amounts of Option Stock, in whole or in part, as set forth in the Vesting 
Schedule on the Notice of Grant.

     5.02     Additional Adjustments.  Notwithstanding the terms of Paragraph 
5.01 of this Agreement, the Board in its sole and exclusive discretion may 
provide for conditions for the exercise of this Option and/or modify the 
Vesting Schedule set forth on the Notice of Grant; provided, however, the 
Board may only modify the conditions for the exercise of this Option and/or 
modify the Vesting Schedule to provide for a more restrictive Vesting 
Schedule with the consent of Optionee, if such modification alters or impairs 
any existing rights or obligations of Optionee under this Option.  

     5.03     Cumulative Exercise Rights.  If the Optionee does not exercise 
in any one year period the full number of shares to which he or she is then 
entitled to exercise, Optionee may exercise those shares in any subsequent 
year prior to the Expiration Date of this Option as set forth on the Notice 
of Grant, or such later date subsequently approved by the Board or its 
delegates.

     5.04     Expiration of Exercise Rights.  Subject to the provisions of 
Paragraph 5.08, in no event shall this Option be exercisable after the 
Expiration Date or such later date subsequently approved by the Board or its 
delegates.

     5.05     Fractional Shares.  This Option shall not be exercisable with 
respect to any fractional shares of the Stock.

     5.06     Exercise Procedure.  This Option shall be exercised by the 
giving of written notice of exercise to the Company which specifies the 
number of shares of Stock to be purchased, accompanied by payment (in 
accordance with the terms of Paragraph 6(d) of the Plan) of the aggregate 
Option Price for the shares of Stock being purchased, such payment to be made 
in any combination of:

              (a)     United States cash currency;

              (b)     a cashier's or certified check to the order of the 
                      Company;

              (c)     a personal check acceptable to the Company;

              (d)     to the extent permitted by the Board, shares of Stock 
                      (including previously owned Stock or Stock issuable in 
                      connection with the Option exercise), 

1996 NS Form Dated:  November 7, 1996                              5 of 9

[PAGE]

                      properly endorsed to the Company, whose Fair Market 
                      Value on the date of exercise equals the aggregate 
                      Option Price of the Option being exercised; or

              (e)     to the extent agreed to by the Board, the Optionee's 
                      entering into an agreement with the Company whereby a 
                      portion of the Optionee's Options are terminated and 
                      where the "built-in gain" on any Options which are 
                      terminated as part of such agreement equals the 
                      aggregate Option Price of the Option being exercised. 
                      "Built-in gain" means the excess of the aggregate Fair 
                      Market Value of any Stock otherwise issuable on 
                      exercise of a terminated Option, over the aggregate 
                      Option Price otherwise due the Company on such 
                      exercise.  

The Board (in accordance with the terms of Paragraph 6(d) of the Plan) may 
provide such assistance to the Optionee to facilitate the exercise of this 
Option as it deems appropriate; provided, however, that the Board, as a 
prerequisite to providing such assistance, may require satisfaction of any 
rules or conditions it deems appropriate.  Shares of Stock used to pay the 
Option Price shall be valued at their Fair Market Value on the date of 
exercise.  The Optionee's notice of exercise shall also be accompanied by 
payment (in accordance with the terms of Paragraph 6(p) of the Plan) of the 
amount of federal and state income and employment taxes that the Company is 
required to collect from Optionee because of the exercise of the Option.

     5.07     Exercise During Life.  Subject to the provisions of Paragraphs 
4.02, 4.03 and 5.08, during Optionee's lifetime, this Option shall be 
exercisable only by Optionee either:

              (a)     while Optionee is employed by or serves as an officer 
                      or director of the Company or its Affiliates;

              (b)     within three (3) months after the date on which 
                      Optionee's employment or term of corporate office 
                      terminates for reasons other than "termination for 
                      cause" as provided in Paragraph 4.03 of this Agreement; 
                      or

              (c)     within one (1) year after the date on which the 
                      Optionee's employment or term of corporate office 
                      terminates due to a Disability;

provided, however, that in no event shall the period of exercise be extended 
beyond the Expiration Date or such later date subsequently approved by the 
Board or its delegates.  Unless the Board or its delegates otherwise agree, 
if Optionee is entitled to purchase shares of Stock after the termination of 
Optionee's employment or termination of his or her corporate office, the 
number of shares of Stock Optionee may so purchase shall be limited to the 
number of shares of Stock Optionee was entitled to purchase as of such date 
of termination.

     5.08     Exercise After Death.  If Optionee dies while employed by or 
while serving as an officer or director of the Company or its Affiliates or 
within a period of three (3) months after the date such employment or term of 
corporate office terminates, but prior to the complete exercise of this 
Option, the Option may be exercised within one (1) year from the date of 
Optionee's death, but:

1996 NS Form Dated:  November 7, 1996                              6 of 9

[PAGE]

              (a)     only by a personal representative of Optionee, or by 
                      any person or persons who shall have acquired the 
                      Option directly from the Optionee by bequest or 
                      inheritance; and

              (b)     only as to the number of shares of Stock that Optionee 
                      was entitled to purchase under this Option on the date 
                      of Optionee's death .

     5.09     Consultancy to the Company After Termination of Employment or 
Term of Corporate Office.  If Optionee acts as a consultant for the Company 
or its Affiliates after the termination of his or her employment or term of 
corporate office, then Optionee shall not be deemed to have terminated his or 
her employment or term of corporate office for the Company or its Affiliates 
for the purposes of Paragraphs 5.07 and 5.08 of this Agreement until Optionee 
ceases to be a consultant for the Company or its Affiliates, provided 
Optionee does not violate any covenant not to compete obligations contained 
in his or her consulting agreement with the Company or its Affiliates.

     5.10     Exercise of Option Prior to Vesting.  The Board, in its sole 
and exclusive discretion, may permit the Optionee to exercise this Option 
prior to the date this Option is otherwise exercisable, provided the Stock 
issued on such exercise is subject to repurchase rights which expire pro rata 
as the Option would otherwise have become exercisable.

     5.11     Non-Sequential Exercise Permitted.  Subject to the exercise 
limitations set forth herein, this Option shall be exercisable 
notwithstanding the fact that there is an outstanding incentive stock option 
or non-statutory stock option for the purchase of Stock of the Company which 
was granted before this Option was granted, and no subsequently-granted 
incentive stock option shall fail to be exercisable solely because this 
Option remains outstanding.

     5.12     Legends.  Certificates for shares of Stock acquired upon 
exercise of this Option may contain such legends and transfer restrictions as 
the Company shall deem reasonably necessary or desirable to:  

              (a)     assure the satisfaction of any liability that the 
                      Company may or will have incurred for withholding of 
                      any federal and state income and employment taxes; 

              (b)     facilitate compliance by the Company with any federal 
                      or state laws or regulations, including, without 
                      limitation, legends restricting transfer of the Stock 
                      until there has been compliance with federal and state 
                      securities laws; 

              (c)     assure notice of the Company's repurchase rights under 
                      Paragraph 5.10 of this Agreement; or 

              (d)     assure notice of such other restrictions as may be 
                      imposed on the Stock under the terms of this Agreement.

1996 NS Form Dated:  November 7, 1996                              7 of 9

[PAGE]


6.     Conflict Between Plan and Agreement.

     This Agreement, including the Option and Optionee's rights hereunder, is 
subject to and governed by the Plan.  Any conflict between the terms and 
provisions of this Agreement and the terms and provisions of the Plan shall 
be governed by the terms and provisions of the Plan.


7.     Investment Intent.

     This Option is granted on the condition that Optionee's purchase of 
Stock shall be for investment purposes for Optionee's own account and not 
with a view to resale or distribution.  The Company shall not, upon the 
exercise of this Option, be required to issue or deliver shares of Stock or 
certificates therefor if, in the opinion of counsel for the Company, such 
issuance or delivery would be in violation of, or would not comply with, any 
applicable state or federal securities law, regulation or rule.


8.     Notices.

     8.01     In Writing.  All notices, demands, requests, declarations, 
service of process, or other communications permitted or required under this 
Agreement or applicable law shall be in writing.

     8.02     Delivery.  All such communications may be served personally or 
may be sent by registered or certified mail, return receipt requested, 
postage prepaid and addressed to either Optionee or the Company at the 
addresses appearing at the top of the Notice of Grant, or at such other 
address as either party shall have communicated to the other pursuant to this 
Paragraph 8.02.  All such communications shall be deemed effectively 
delivered upon personal service or three (3) days after deposit in the United 
States Mail.


9.     Miscellaneous.

     9.01     Successors and Assigns.  Except as otherwise provided in this 
Agreement, this Agreement shall inure to the benefit of only the Company, 
Optionee and their respective successors or assigns.

     9.02     Status.  Nothing contained in this Agreement shall be construed 
as giving Optionee any right to be retained as an Employee, officer or 
director of the Company.

     9.03     Severability.  If any provision or provisions of this Agreement 
are adjudged to be, for any reason, unenforceable, illegal or void, the 
remainder of the provisions shall remain in full force and effect.

     9.04     Integration.  This Agreement and the Notice of Grant to which 
this Agreement is an attachment constitute the entire understanding of the 
parties concerning this Option.  Except as otherwise provided, any changes, 
modifications, variations, or subordinations pertaining to this 

1996 NS Form Dated:  November 7, 1996                              8 of 9

[PAGE]

Agreement and the Notice of Grant are invalid, unless stated in writing and 
executed by the Company and Optionee.

     9.05     Governing Law.  This Agreement and the Option granted hereby 
shall be governed by the laws of the State of California.

     9.06     Attorneys' Fees.  If either party brings an action or seeks to 
enforce or interpret any of the terms or provisions of this Agreement, the 
prevailing party shall be entitled to recover its reasonable attorneys' fees 
and costs, in addition to any other remedy it may be awarded.

     9.07     Counterparts.  This Agreement may be executed in counterparts, 
and the counterparts shall constitute the whole instrument.

     9.08     Titles for Convenience; Gender; and Plurals.  Titles of 
articles and paragraph headings are for convenience only and shall not affect 
the construction or interpretation of this Agreement, or any portion thereof.  
Whenever required by the context hereof, the singular shall include the 
plural, and vice versa; the masculine gender shall include the feminine and 
neuter, and vice versa.


1996 NS Form Dated:  November 7, 1996                              9 of 9

[PAGE]





                                                             EXHIBIT 99.5

                                ATTACHMENT NO. 1
                                      TO
                       NOTICE OF GRANT OF STOCK OPTION

                        AGOURON PHARMACEUTICALS, INC.
                         (a California Corporation)

                 1996 NON-STATUTORY STOCK OPTION AGREEMENT
                               FOR CONSULTANTS


     This Option Agreement is entered into between Agouron Pharmaceuticals, 
Inc., a California corporation and the Optionee whose name appears on the 
Notice of Grant of Stock Option to which this Agreement is an attachment.


1.     Recitals.

     1.01     The Board of Directors of the Company or its duly authorized 
delegates authorized the granting of this Option to Optionee who is a 
Consultant to the Company or its Affiliates pursuant to the Agouron 
Pharmaceuticals, Inc. 1996 Stock Option Plan.

     1.02     This Option Agreement is intended to constitute a non-statutory 
stock option, meaning an option which is not an "incentive stock option" 
within the meaning of Section 422 of Internal Revenue Code of 1986, as 
amended from time to time.


2.     Definitions.

     In addition to those words and phrases defined above and unless 
otherwise required by the context in which they appear, words and phrases 
having their initial letters capitalized shall have the following meanings:

     2.01     Act.  "Act" shall mean the Securities Exchange Act of 1934, as 
amended from time to time.

     2.02     Affiliate.  "Affiliate" shall mean any corporation defined as a 
"parent corporation" or a "subsidiary corporation" by Code Section 424(e) and 
(f), respectively.

     2.03     Agreement.  "Agreement" shall mean this 1996 Non-Statutory 
Stock Option Agreement for Consultants (including any schedules, attachments, 
documents incorporated by reference, or modifications agreed to in writing by 
the Company and Optionee) which sets forth the Optionee's and the Company's 
rights and obligations with respect to the Option granted Optionee by the 
Board or its duly authorized delegates as described on the Notice of Grant.

     2.04     Board.  "Board" shall mean the Board of Directors of the 
Company.

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[PAGE]

     2.05     Code.  "Code" shall mean the Internal Revenue Code of 1986, as 
amended from time to time.

     2.06     Company.  "Company" shall mean Agouron Pharmaceuticals, Inc., a 
California corporation, and any successors or assigns.

     2.07     Consultant.  "Consultant" shall mean any person who is placed 
on the Corporation's Consultants List by the Board or its duly authorized 
delegates and who agrees in writing to be included thereon.

     2.08     Consultant's Agreement.  "Consultant's Agreement" shall mean a 
consulting agreement between Optionee and the Company and/or its Affiliates.

     2.09     Date of Grant.  "Date of Grant" shall mean the Date of Grant 
set forth on the Notice of Grant.

     2.10     Disability.  "Disability" or "Disabled" shall mean the 
condition of being "disabled" within the meaning of Section 422(c)(6) of the 
Code or any successor provision. 

     2.11     Expiration Date.  "Expiration Date" shall mean the Expiration 
Date set forth on the Notice of Grant.

     2.12     Fair Market Value.  "Fair Market Value" of Stock on a given 
date shall mean an amount per share, as determined by the Board or its 
delegates by applying any reasonable valuation method determined without 
regard to any restriction other than a restriction which, by its terms, will 
never lapse.  Notwithstanding the preceding, if the Stock is traded upon an 
established stock exchange, then the "Fair Market Value" of Stock on a given 
date per share shall be deemed to be the average of the highest and lowest 
selling price per share of the Stock on the principal stock exchange on which 
the Stock is then trading or, if there was no trading of the Stock on that 
day, on the next preceding day on which there was such trading; if the Stock 
is not traded upon an established stock exchange but is quoted on a quotation 
system, the "Fair Market Value" of Stock on a given date shall be deemed to 
be the mean between the closing representative "bid" and "ask" prices per 
share of the Stock on such date as reported by such quotation system or, if 
there was no trading of the Stock on that day, on the next preceding day on 
which there was such trading.

     2.13     Notice of Grant of Stock Option.  "Notice of Grant of Stock 
Option" or "Notice of Grant" shall mean the Notice of Grant executed by the 
Company and the Optionee to which this Agreement is an attachment.

     2.14     Option.  "Option" shall mean the right of Optionee to purchase 
the number of shares of Stock set forth on the Notice of Grant in accordance 
with the terms and conditions of this Agreement.

     2.15     Optionee.  "Optionee" shall mean the person whose name is set 
forth on the Notice of Grant.

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[PAGE]

     2.16     Option Price.  "Option Price" shall mean the price per share of 
Stock to be paid by the Optionee upon exercise of the Option, which amount is 
set forth on the Notice of Grant.

     2.17     Option Stock.  "Option Stock" shall mean the total number of 
shares of Stock the Optionee shall be entitled to purchase pursuant to this 
Agreement, which number of shares is set forth on the Notice of Grant.

     2.18     Plan.  "Plan" shall mean the 1996 Agouron Pharmaceuticals, Inc. 
Stock Option Plan, as amended from time to time.

     2.19     Reporting Person.  "Reporting Person" shall mean an Optionee 
who is required to file statements relating to his or her beneficial 
ownership of Stock with the SEC pursuant to Section 16(a) of the Act.

     2.20     Rule 16b-3.  "Rule 16b-3" shall mean Rule 16b-3 (as amended 
from time to time) promulgated by the SEC under the Act, and any successor 
thereto.

     2.21     SEC.  "SEC" shall mean the Securities and Exchange Commission.

     2.22     Stock.  "Stock" shall mean the no par common stock of the 
Company.

     2.23     Vesting.  "Vesting" shall mean the date(s) when all or a 
portion of the Option Stock becomes available for exercise.

     2.24     Vesting Schedule.  "Vesting Schedule" shall mean the Vesting 
Schedule set forth on the Notice of Grant which indicates on what dates all 
or a portion of the Option Stock becomes available for exercise.

3.     Option.

     3.01     Grant.  The Company hereby grants to Optionee an Option to 
purchase all or any part of the Option Stock on the terms and conditions set 
forth in this Agreement.  The Date of Grant shall be the Date of Grant set 
forth on the Notice of Grant.

     3.02     Purchase Price.  The purchase price per share of Stock to be 
paid upon the exercise of this Option shall be the Option Price set forth on 
the Notice of Grant.

     3.03     Restrictions on Transfer.  This Option may be transferred to a 
trust for the benefit of the Optionee or members of his or her immediate 
family.  Upon any attempt to sell, assign, encumber or otherwise transfer 
this Option in violation of this Agreement, or upon the levy of any 
attachment or similar process upon this Option, this Option shall immediately 
become null and void.

     3.04     Modifications of Rights.  As set forth in Paragraph 6(l) of the 
Plan, the Board may modify (including, lowering the Option Price), extend or 
renew this Option (to the extent not previously exercised), or accept the 
surrender of this Option (to the extent not previously exercised)

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[PAGE]

and authorize the granting of a new Stock option in substitution therefor; 
provided, however, that no modification of this Option shall, without the 
consent of the Optionee, alter or impair any existing rights or obligations 
of Optionee under this Option.

     3.05     Changes in Company's Equity Structure; Recapitalization of 
Company.  Upon the occurrence of the capital and/or recapitalization 
transactions described in Paragraph 6(j) of the Plan, this Option (to the 
extent not previously exercised) shall be adjusted or modified as provided in 
Paragraph 6(j) of the Plan.  Notwithstanding any provision of this Agreement, 
the Company reserves the right to:

              (a)     make or enter into any adjustments, reclassifications, 
                      reorganizations or changes of its capital or business 
                      structure;

              (b)     merge or consolidate with other entities; or

              (c)     dissolve, liquidate or sell, or transfer all or any 
                      part of its business or assets.

     3.06     Shareholder's Rights.  Optionee shall have no rights as a 
shareholder with respect to any shares Optionee is entitled to purchase under 
this Option until the date of the issuance of a stock certificate for such 
shares.  No adjustment shall be made for dividends (ordinary or 
extraordinary, whether in cash, securities or other property) or 
distributions or other rights for which the record date is prior to the date 
of issuance of such certificate, except as provided in this Agreement or in 
the Plan.


4.     Consultant Conditions.

     4.01     Consultant's Agreement.  Optionee shall be considered to be 
engaged by the Company and its Affiliates until the date of termination of 
Optionee's engagement under the terms of his or her Consultant's Agreement. 
The Board, in accordance with the terms of Optionee's Consultant's Agreement 
shall determine: 

              (a)     whether or when there has been a termination of 
                      Optionee's engagement by the Company and its 
                      Affiliates;

              (b)     if there has been a failure to comply with Optionee's 
                      covenant not to compete obligations; and 

              (c)     the cause of such termination, 

which determination shall be final.

     4.02     Covenant Not to Compete.  Failure of Optionee to comply with 
the covenant not to compete obligations under the terms of his or her 
Consultant's Agreement within thirty (30) days of written notice of such 
failure shall cause, on the thirtieth (30th) day after such written notice, 
the cancellation of Optionee's right to purchase Option Stock (to the extent 
not previously exercised) without further action by the Company.  

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[PAGE]

     4.03     Termination for Cause.  If Optionee's engagement under the 
terms of his or her Consultant's Agreement is terminated for cause, the right 
of Optionee to purchase Option Stock shall only be exercisable for a period 
of thirty (30) days after the date of such termination.


5.     Exercise.

     5.01     Exercise Amounts.  Subject to the earlier termination of the 
right to exercise this Option as provided under this Agreement, including 
Paragraphs 4.02 and 4.03 above, the Optionee shall be entitled to exercise 
the amounts of Option Stock, in whole or in part, as set forth in the Vesting 
Schedule on the Notice of Grant.

     5.02     Additional Adjustments.  Notwithstanding the terms of Paragraph 
5.01 of this Agreement, the Board in its sole and exclusive discretion may 
provide for conditions for the exercise of this Option and/or modify the 
Vesting Schedule set forth on the Notice of Grant; provided, however, the 
Board may only modify the conditions for the exercise of this Option and/or 
modify the Vesting Schedule to provide for a more restrictive Vesting 
Schedule with the consent of Optionee, if such modification alters or impairs 
any existing rights or obligations of Optionee under this Option.  

     5.03     Cumulative Exercise Rights.  If the Optionee does not exercise 
in any one year period the full number of shares to which he or she is then 
entitled to exercise, Optionee may exercise those shares in any subsequent 
year prior to the Expiration Date of this Option as set forth on the Notice 
of Grant, or such later date subsequently approved by the Board or its 
delegates.

     5.04     Expiration of Exercise Rights.  Subject to the provisions of 
Paragraph 5.08, in no event shall this Option be exercisable after the 
Expiration Date or such later date subsequently approved by the Board or its 
delegates.

     5.05     Fractional Shares.  This Option shall not be exercisable with 
respect to any fractional shares of the Stock.

     5.06     Exercise Procedure.  This Option shall be exercised by the 
giving of written notice of exercise to the Company which specifies the 
number of shares of Stock to be purchased, accompanied by payment (in 
accordance with the terms of Paragraph 6(d) of the Plan) of the aggregate 
Option Price for the shares of Stock being purchased, such payment to be made 
in any combination of:

              (a)     United States cash currency;

              (b)     a cashier's or certified check to the order of the 
                      Company;

              (c)     a personal check acceptable to the Company;

              (d)     to the extent permitted by the Board, shares of Stock 
                      (including previously owned Stock or Stock issuable in 
                      connection with the Option exercise), properly endorsed 
                      to the Company, whose Fair Market Value on the date of 
                      exercise equals the aggregate Option Price of the 
                      Option being exercised; or

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              (e)     to the extent agreed to by the Board, the Optionee's 
                      entering into an agreement with the Company whereby a 
                      portion of the Optionee's Options are terminated and 
                      where the "built-in gain" on any Options which are 
                      terminated as part of such agreement equals the 
                      aggregate Option Price of the Option being exercised. 
                      "Built-in gain" means the excess of the aggregate Fair 
                      Market Value of any Stock otherwise issuable on 
                      exercise of a terminated Option, over the aggregate 
                      Option Price otherwise due the Company on such 
                      exercise.  

The Board (in accordance with the terms of Paragraph 6(d) of the Plan) may 
provide such assistance to the Optionee to facilitate the exercise of this 
Option as it deems appropriate; provided, however, that the Board, as a 
prerequisite to providing such assistance, may require satisfaction of any 
rules or conditions it deems appropriate.  Shares of Stock used to pay the 
Option Price shall be valued at their Fair Market Value on the date of 
exercise.  The Optionee's notice of exercise shall also be accompanied by 
payment (in accordance with the terms of Paragraph 6(p) of the Plan) of the 
amount of federal and state income and employment taxes that the Company is 
required to collect from Optionee because of the exercise of the Option.

     5.07     Exercise During Life.  Subject to the provisions of Paragraphs 
4.02, 4.03 and 5.08, during Optionee's lifetime, this Option shall be 
exercisable only by Optionee either:

              (a)     while Optionee is engaged by the Company or its 
                      Affiliates under the terms of his or her Consultant's 
                      Agreement;

              (b)     within three (3) months after the date on which 
                      Optionee's engagement terminates for reasons other than 
                      "termination for cause" under the terms of his or her 
                      Consultant's Agreement and as provided in Paragraph 
                      4.03 of this Agreement; or

              (c)     within one (1) year after the date on which the 
                      Optionee's engagement terminates due to a Disability 
                      under the terms of his or her Consultant's Agreement;

provided, however, that in no event shall the period of exercise be extended 
beyond the Expiration Date or such later date subsequently approved by the 
Board or its delegates.  Unless the Board or its delegates otherwise agree, 
if Optionee is entitled to purchase shares of Stock after the termination of 
Optionee's engagement under his or her Consultant's Agreement, the number of 
shares of Stock Optionee may so purchase shall be limited to the number of 
shares of Stock Optionee was entitled to purchase as of such date of 
termination.

     5.08     Exercise After Death.  If Optionee dies while engaged by the 
Company or its Affiliates under the terms of his or her Consultant's 
Agreement or within a period of three (3) months after the date such 
engagement terminates, but prior to the complete exercise of this Option, the 
Option may be exercised within one (1) year from the date of Optionee's 
death, but:

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              (a)     only by a personal representative of Optionee, or by 
                      any person or persons who shall have acquired the 
                      Option directly from the Optionee by bequest or 
                      inheritance; and

              (b)     only as to the number of shares of Stock that Optionee 
                      was entitled to purchase under this Option on the date 
                      of Optionee's death .

     5.09     Exercise of Option Prior to Vesting.  The Board, in its sole 
and exclusive discretion, may permit the Optionee to exercise this Option 
prior to the date this Option is otherwise exercisable, provided the Stock 
issued on such exercise is subject to repurchase rights which expire pro rata 
as the Option would otherwise have become exercisable.

     5.10     Non-Sequential Exercise Permitted.  Subject to the exercise 
limitations set forth herein, this Option shall be exercisable 
notwithstanding the fact that there is an outstanding incentive stock option 
or non-statutory stock option for the purchase of Stock of the Company which 
was granted before this Option was granted, and no subsequently-granted 
incentive stock option shall fail to be exercisable solely because this 
Option remains outstanding.

     5.11     Legends.  Certificates for shares of Stock acquired upon 
exercise of this Option may contain such legends and transfer restrictions as 
the Company shall deem reasonably necessary or desirable to:  

              (a)     assure the satisfaction of any liability that the 
                      Company may or will have incurred for withholding of 
                      any federal and state income and employment taxes; 

              (b)     facilitate compliance by the Company with any federal 
                      or state laws or regulations, including, without 
                      limitation, legends restricting transfer of the Stock 
                      until there has been compliance with federal and state 
                      securities laws; 

              (c)     assure notice of the Company's repurchase rights under 
                      Paragraph 5.09 of this Agreement; or 

              (d)     assure notice of such other restrictions as may be 
                      imposed on the Stock under the terms of this Agreement.


6.     Conflict Between Plan and Agreement.

     This Agreement, including the Option and Optionee's rights hereunder, is 
subject to and governed by the Plan.  Any conflict between the terms and 
provisions of this Agreement and the terms and provisions of the Plan shall 
be governed by the terms and provisions of the Plan.

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[PAGE]


7.     Investment Intent.

     This Option is granted on the condition that Optionee's purchase of 
Stock shall be for investment purposes for Optionee's own account and not 
with a view to resale or distribution.  The Company shall not, upon the 
exercise of this Option, be required to issue or deliver shares of Stock or 
certificates therefor if, in the opinion of counsel for the Company, such 
issuance or delivery would be in violation of, or would not comply with, any 
applicable state or federal securities law, regulation or rule.


8.     Notices.

     8.01     In Writing.  All notices, demands, requests, declarations, 
service of process, or other communications permitted or required under this 
Agreement or applicable law shall be in writing.

     8.02     Delivery.  All such communications may be served personally or 
may be sent by registered or certified mail, return receipt requested, 
postage prepaid and addressed to either Optionee or the Company at the 
addresses appearing at the top of the Notice of Grant, or at such other 
address as either party shall have communicated to the other pursuant to this 
Paragraph 8.02.  All such communications shall be deemed effectively 
delivered upon personal service or three (3) days after deposit in the United 
States Mail.


9.     Miscellaneous.

     9.01     Successors and Assigns.  Except as otherwise provided in this 
Agreement, this Agreement shall inure to the benefit of only the Company, 
Optionee and their respective successors or assigns.

     9.02     No Right to be a Consultant.  Nothing contained in this 
Agreement shall be construed as giving Optionee any right to be retained as a 
consultant for the Company.

     9.03     Severability.  If any provision or provisions of this Agreement 
are adjudged to be, for any reason, unenforceable, illegal or void, the 
remainder of the provisions shall remain in full force and effect.

     9.04     Integration.  This Agreement and the Notice of Grant to which 
this Agreement is an attachment constitute the entire understanding of the 
parties concerning this Option.  Except as otherwise provided, any changes, 
modifications, variations, or subordinations pertaining to this Agreement and 
the Notice of Grant are invalid, unless stated in writing and executed by the 
Company and Optionee.

     9.05     Governing Law.  This Agreement and the Option granted hereby 
shall be governed by the laws of the State of California.

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     9.06     Attorneys' Fees.  If either party brings an action or seeks to 
enforce or interpret any of the terms or provisions of this Agreement, the 
prevailing party shall be entitled to recover its reasonable attorneys' fees 
and costs, in addition to any other remedy it may be awarded.

     9.07     Counterparts.  This Agreement may be executed in counterparts, 
and the counterparts shall constitute the whole instrument.

     9.08     Titles for Convenience; Gender; and Plurals.  Titles of 
articles and paragraph headings are for convenience only and shall not affect 
the construction or interpretation of this Agreement, or any portion thereof.  
Whenever required by the context hereof, the singular shall include the 
plural, and vice versa; the masculine gender shall include the feminine and 
neuter, and vice versa.

     9.09     Consultants List.  Consultant's execution of this Agreement 
indicates his written agreement to be placed on the Company's Consultants 
List.

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