AGOURON PHARMACEUTICALS INC
8-K, 1997-05-05
PHARMACEUTICAL PREPARATIONS
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                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549


                                    FORM 8-K

                                 CURRENT REPORT


                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934


             Date of Report (Date of Event Reported): April 28, 1997





                          AGOURON PHARMACEUTICALS, INC.
                        ---------------------------------
             (Exact name of registrant as specified in its charter)




            California             0-15609            33-0061928
          --------------         -----------         ------------
 (State or other jurisdiction    (Commission         (IRS Employer
      of incorporation)          File Number)    Identification Number)



       10350 North Torrey Pines Road                                 92037
              La Jolla, California
  ---------------------------------------------------------------------------
 (Address of principal executive offices)                         Zip Code



                                 (619) 622-3000
 ----------------------------------------------------------------------------
           (Registrant's telephone number, including area code)



<PAGE>


Item 5.       Other Events.

              On April 28, 1997, the Registrant signed a definitive agreement to
acquire  Alanex  Corporation,  a  privately  held drug  discovery  company,  for
1,000,000  shares of newly issued  Agouron  common  stock.  The  transaction  is
expected  to close in  approximately  thirty  (30) days.  See the Press  Release
attached as Exhibit 99.2.

Item 7.       Financial Statements and Exhibits.

              (c) Exhibits.

                  Exhibit Number

                  99.2     Form of Press Release dated April 29, 1997.



<PAGE>


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended,
the  Registrant  has duly  caused  this report to be signed on its behalf by the
undersigned hereunto duly authorized.

         Dated:   May 2, 1997

                          AGOURON PHARMACEUTICALS, INC.


                                              By  /s/ Peter Johnson
                                                  ----------------------------
                                                  Peter Johnson
                                                  President and
                                                  Chief Executive Officer



<PAGE>


EXHIBIT INDEX

        Exhibit No.        Description                                     

            99.2           Form of Press Release dated April 29, 1997.


      
Contact:
Donna Nichols  (619) 622-3009
Senior Director, Corporate Communications


                                For Release at 9:00 a.m. EDT on April 29, 1997
                                ----------------------------------------------
   
                       AGOURON ACQUIRES ALANEX CORPORATION

   LA JOLLA,  Calif.,  April 29, 1997 -- Agouron  Pharmaceuticals,  Inc. (Nasdaq
NNM: AGPH) announced today that it has signed a definitive  agreement to acquire
Alanex  Corporation,  a privately  held drug  discovery  company,  for 1,000,000
shares of newly issued  Agouron  common stock.  The  transaction  is expected to
close in approximately 30 days.

   Alanex,  located in San Diego,  is  engaged  in the  discovery  of drug leads
through the  high-speed  screening  of diverse  chemical  libraries  designed by
computational methods and generated by combinatorial chemistry.  Alanex utilizes
proprietary  software to design  either broad or highly  targeted  combinatorial
libraries of molecules that can readily be  synthesized  in large numbers.  With
approximately 80 employees,  Alanex is presently  conducting  research  projects
aimed at discovery of drugs for such therapeutic  indications as pain, diabetes,
obesity,   anxiety,   and  certain  malignant   tumors.   Alanex  currently  has
collaborative  arrangements with Aurora  Biosciences,  Astra Pharma,  Inc., Novo
Nordisk, and Roche Bioscience.

   A leader  in the  design  of  small  molecule  drugs  based  upon  the  three
dimensional structures of proteins that play key roles in human disease, Agouron
currently markets its first commercial product,  an HIV protease  inhibitor,  in
the United States and is engaged in the research and  development of more than a
dozen other products.

   "We have  believed for some time that the  integration  of  technologies  for
three-dimensional,   structure-based   drug   design   with   technologies   for
computation-directed combinatorial chemistry and high throughput screening could
be an extremely powerful force in drug discovery with immediate  benefits," said
Peter Johnson,  Agouron's  president and chief executive officer.  "We were very
impressed  by the  competitive  position  of  Alanex  in the  area  of  targeted
combinatorial  chemistry  and  impressed  by  the  contributions  that  Alanex's
proprietary research projects could make to our development  pipeline.  The fact
that Alanex is well funded through collaborative arrangements with

                                     -more-

<PAGE>

excellent pharmaceutical partners made the merger all the more attractive to 
Agouron."

   Current  employees of Alanex are generally  expected to become employees of a
subsidiary of Agouron to be headed by Marvin Brown,  M.D.,  currently  president
and chief executive  officer of Alanex  Corporation.  The Alanex subsidiary will
continue to engage in collaborative  research programs with  pharmaceutical  and
biotechnology  companies,  will independently carry out certain proprietary drug
discovery  programs,  and  will  have  access  to the  product  development  and
marketing capabilities of Agouron.

   "The  acquisition  of Alanex is not expected to have a significant  impact on
Agouron's  near-term  financial  condition," said Steven Cowell,  Agouron's vice
president and chief financial officer.  "While the acquisition is expected to be
accounted for as a purchase and generate a  significant  write-off of in-process
R&D in the  fourth  quarter of  Agouron's  fiscal  year  ending  June 30,  1997,
revenues from Alanex's existing and anticipated  collaborative  arrangements are
expected to substantially offset its operating expenses in fiscal 1998."

   "We are excited to accept this unique  opportunity to merge the discovery 
technologies of our two companies,"  said Dr. Brown.  "Access to Agouron's 
development and marketing  capabilities will also assure the progress of 
Alanex's proprietary development projects."

   PaineWebber   Incorporated   acted  as  advisor  to  Agouron  in  the  merger
transaction; Lehman Brothers acted as advisor to Alanex.

   Agouron  Pharmaceuticals,  Inc.  is an  integrated  pharmaceutical  company 
committed  to the  discovery,  development, manufacturing and marketing of small
molecule drugs for treatment of serious diseases.

   Certain statements in this news release consist of forward-looking statements
that  involve  risks  and   uncertainties,   including,   but  not  limited  to,
uncertainties regarding future collaborative research programs and financial and
other representations made by management. Other risks may exist as detailed from
time to time in the  reports  filed  by the  company  with  the  Securities  and
Exchange Commission, including the company's reports on Forms 10-K and 10-Q.
                                   ###



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