THERMOGENESIS CORP
S-3, 1999-02-09
LABORATORY APPARATUS & FURNITURE
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As filed with the Securities and Exchange           Registration No. 333-_____
 Commission on February 8, 1999  


                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM S-3
             REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933

                               THERMOGENESIS CORP.
             (Exact name of the Company as specified in its charter)


           Delaware                                         94-3018487
(State or other jurisdiction or incorporation          (I.R.S. Employer 
 or organization)                                       Identification Number)



                              3146 Gold Camp Drive
                        Rancho Cordova, California 95670
                                 (916) 858-5100
               (Address, including zip code, and telephone number,
                 including area code, of registrant's principal
                               executive offices)

                                Philip H. Coelho
                             Chief Executive Officer
                               THERMOGENESIS CORP.
                              3146 Gold Camp Drive
                            Rancho Cordova, CA 95670
                                 (916) 858-5100
       (Name, address, including zip code, and telephone number, including
                        area code, of agent for service)

                                   Copies to:

     David C. Adams, Esq.                             Daniel B. Eng, Esq.
      General Counsel                             BARTEL ENG LINN & SCHRODER
     THERMOGENESIS CORP.                         300 Capitol Mall, Suite 1100
     3146 Gold Camp Drive                             Sacramento, CA 95814
  Rancho Cordova, California 95670                       (916) 442-0400
         (916) 858-5110

Approximate date of commencement of the proposed sale to the public:  As soon as
practicable, and from time to time after the effective date of this Registration
Statement.

If the only securities  being registered on this Form are being offered pursuant
to dividend or interest reinvestment plans, please check the following box. [ ]

If any of the  securities  being  registered on this Form are to be offered on a
delayed or continuous  basis  pursuant to Rule 415 under the  Securities  Act of
1933, other than securities offered only in connection with dividend or interest
reinvestment plans, check the following box. [X]

If this Form is filed to register additional securities for an offering pursuant
to Rule 462(b) under the Securities Act, please check the following box and list
the  Securities  Act  registration  statement  number of the  earlier  effective
registration statement for the same offering. [ ]

If this Form is a  post-effective  amendment filed pursuant to Rule 462(c) under
the  Securities  Act,  check  the  following  box and  list the  Securities  Act
registration  statement number of the earlier effective  registration  statement
for the same offering. [ ]

If delivery  of the  prospectus  is  expected  to be made  pursuant to Rule 434,
please check the following box. [ ]

<PAGE>ii



                         CALCULATION OF REGISTRATION FEE


<TABLE>

<S>                                  <C>               <C>             <C>            <C>   
                                                        Proposed        Proposed
                                                        maximum          maximum       Amount of
      Title of each class of         Amount to be    offering price     aggregate     registration
    securities to be registered       registered        per share     offering price       fee
- --------------------------------     -------------   --------------  --------------   -------------
Common Stock Underlying Series A
Preferred Stock                       5,387,700 (1)      $2.625 (3)     $14,142,712    $4,172.10
Common Stock Underlying Placement
Agent Warrant                           200,000 (2)      $2.625 (4)        $525,000      $154.88
Common Stock Underlying Warrants         90,000 (2)      $2.625 (4)        $236,250       $69.69
Total                                 5,677,700                         $14,903,962     $4,396.67

</TABLE>

(1)     Represents the number of shares of common stock for resale upon the 
        conversion of the Series A preferred stock.

(2)     Represents  the  number  of shares of common stock for resale  upon the
        exercise of warrants.

(3)     Calculated in accordance with Rule 457(c) of the Securities Act of 1933,
        as  amended  ("Securities  Act").  Estimated  for the  sole  purpose  of
        calculating the  registration fee and based upon the average of the high
        and low price per share of the common stock of  THERMOGENESIS  CORP.  on
        February 4, 1999, as reported on the Nasdaq SmallCap Market.

(4)     Calculated in accordance with Rule 457(g) of the Securities Act.

The registrant hereby amends this  registration  statement on such date or dates
as may be necessary to delay its effective date until the registrant  shall file
a further amendment which specifically  states that this registration  statement
shall  thereafter  become  effective  in  accordance  with  Section  8(a) of the
Securities  Act of  1933  or  until  the  registration  statement  shall  become
effective on such date as the Commission,  acting pursuant to said section 8(a),
may determine.



<PAGE>1



Subject to Completion February 8, 1999                              PROSPECTUS


                                5,677,700 Shares

                               THERMOGENESIS CORP.

                                  Common Stock


        All of the shares of common  stock of  THERMOGENESIS  CORP.  offered are
being  sold by selling  stockholders  listed in this  prospectus.  Of the shares
being sold by the selling  stockholders,  up to  5,387,700  shares may be resold
upon the conversion of Series A Convertible  Redeemable  Preferred Stock, and up
to 290,000 shares may be resold upon the exercise of outstanding  warrants.  The
Series A  preferred  stock  and  warrants  were  issued  in  private  placements
completed in November  1998 and January  1999.  We will not receive any proceeds
from the sale of any common stock by the selling stockholders.

        Our  common  stock is traded  and  listed on The  Nasdaq  Stock  Market,
SmallCap Market, under the symbol "KOOL." On February 4, 1999, the last reported
sale price for the common stock was  $2.6875.  There is no market for either the
Series A preferred stock or the warrants. We are required to register the shares
for resale and will pay for expenses related to this prospectus  estimated to be
$15,000.






                        -------------------------------

          INVESTING IN OUR COMMON STOCK INVOLVES A HIGH DEGREE OF RISK.
                          SEE "RISK FACTORS" AT PAGE 5.
                         -------------------------------

NEITHER  THE  SECURITIES  AND  EXCHANGE  COMMISSION  NOR  ANY  STATE  SECURITIES
COMMISSION HAS APPROVED OR DISAPPROVED OF THE COMMON STOCK OR DETERMINED IF THIS
PROSPECTUS  IS TRUTHFUL OR  COMPLETE.  ANY  REPRESENTATION  TO THE CONTRARY IS A
CRIMINAL OFFENSE.

                         -------------------------------




                The date of this Prospectus is February 8, 1999.




<PAGE>2



                              AVAILABLE INFORMATION

        THERMOGENESIS CORP. files annual,  quarterly and current reports,  proxy
statements and other  information  with the Securities and Exchange  Commission.
You may read and copy any reports,  statements or other  information  on file at
the  Commission's  public  reference  room in  Washington,  D.C. You can request
copies of those documents,  upon payment of a duplicating fee, by writing to the
Commission.

        THERMOGENESIS CORP. has filed a registration  statement on Form S-3 with
the  Commission.  This  prospectus,  which  forms a part  of  that  registration
statement,  does  not  contain  all  information  included  in the  registration
statement.   Certain  information  is  omitted  and  you  should  refer  to  the
registration statement and its exhibits. With respect to references made in this
prospectus  to any  contract  or other  document  of  THEMOGENESIS  CORP.,  such
references  are not  necessarily  complete  and you should refer to the exhibits
attached  to the  registration  statement  for copies of the actual  contract or
document.   You  may  review  a  copy  of  the  registration  statement  at  the
Commission's  public  reference room, and at the  Commission's  regional offices
located in Chicago,  Illinois and New York, New York. Please call the Commission
at  1-800-SEC-0330  for  further  information  on the  operation  of the  public
reference rooms. THEMOGENESIS CORP.'s filings and the registration statement can
also be reviewed by accessing the Commission's website at http://www.sec.gov.

                 INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

        The Commission  allows us to  "incorporate by reference" the information
we file with them, which means that we can disclose important information to you
by referring you to those documents.  The information  incorporated by reference
is considered part of this  prospectus,  and information that we file later with
the Commission will  automatically  update and supersede the information in this
prospectus.  We  incorporate  by reference  the  documents  listed below and any
future filings we make with the Commission  under Sections  13(a),  13(c), 14 or
15(d) of the Securities Exchange Act of 1934 until the selling stockholders sell
all the shares offered by this prospectus.

        (1) Annual Report on Form 10-K for the year ended June 30, 1998;

        (2) Quarterly  Report on Form 10-Q for the quarter  ended  September 30,
            1998;

        (3) Current Report on Form 8-K for the event dated January 14, 1999;

        (4) Proxy Statement for the Annual Meeting of  Stockholders  held on
            December 11, 1998; and

        (5) The  description of  THEMOGENESIS  CORP.'s common stock contained in
            Form 8-A.

        THERMOGENESIS  CORP.'s  Exchange  Act file  number is  0-16375.  You may
request a copy of these filings at no cost, by writing or  telephoning us at the
following address:  THERMOGENESIS  CORP., 3146 Gold Camp Drive,  Rancho Cordova,
California 95670, Attention: Corporate Secretary; telephone (916) 858-5100.



<PAGE>3



                               PROSPECTUS SUMMARY

        This  summary  highlights   information   contained  elsewhere  in  this
prospectus.  This  summary  is not  complete  and  does not  contain  all of the
information  that you should consider before  investing in the common stock. You
should  carefully  read the  entire  prospectus,  including  the  documents  and
information   incorporated  by  reference  into  it.  This  Prospectus  contains
forward-looking statements that are subject to risks and uncertainties,  such as
THERMOGENESIS  CORP.'s  products being subject to regulatory  approvals,  market
acceptance of new technologies, and other risks detailed in the section entitled
Risk  Factors  and in  THERMOGENESIS  CORP.'s  Annual  Report as filed  with the
Commission. A glossary of certain technical terms used is located at the back of
the Prospectus.

Our Business

THERMOGENESIS    CORP.   is   a   leading    developer   and   manufacturer   of
micro-manufacturing  systems  designed to harvest  biopharmaceutical  drugs from
blood.  Biopharmaceutical drugs utilize the body's naturally occurring proteins,
enzymes,  growth  factors,  hormones and  progenitor  cells for the treatment of
human disease.  THERMOGENESIS  CORP.'s  technology  platforms  micro-manufacture
biopharmaceutical  drugs from a single  donation of blood in contrast to "pools"
of blood from thousands of donors or expensive recombinant technology.

Our Strategy

Our strategy to exploit our market opportunity includes the following:

        o       Utilize our expertise in the areas of thermodynamics and
                cryopreservation.

        o      Develop  products  through platform designs to build new products
               with  only  a  small   incremental   research   and   development
               investment.

        o      Become the leader in the  design,  development,  manufacture  and
               sale of medical  devices  which produce  biopharmaceutical  drugs
               from an  autologous  or  directed  single  donor unit of blood to
               reduce or  eliminate  contamination  and risk of infection to the
               recipient.

        o      Develop disposable products which are used with platform designed
               products to provide a recurrent stream of revenue.

Our History

THERMOGENESIS   CORP.'s  core  expertise   lies  in  the  technical   fields  of
thermodynamics, and cryopreservation;  technologies that it initially applied to
the   development   of  ultra  rapid   freezers  and  thawers,   Food  and  Drug
Administration  ("FDA") class I products currently being sold to blood banks and
hospitals  in 32 countries  throughout  the world.  Until the fourth  quarter of
fiscal year 1998,  THERMOGENESIS  CORP.'s revenues had been principally  derived
from  these  core  products.  Following  four years of  intensive  research  and
development  THERMOGENESIS  CORP. began shipping in the second quarter of fiscal
year 1998 its first new biopharmaceutical  drug micro- manufacturing system, the
BioArchiveTM  System,  a  computer  controlled  liquid  nitrogen  platform  with
dedicated  disposables  for the  manufacture,  cryopreservation  and  archive of

<PAGE>4


hematopoietic stem and progenitor cells sourced from placental cord blood, which
is used to reconstitute  the immune system of patients  suffering from leukemia,
lymphoma,  diverse inherited anemias, or hypoproliferative  stem cell disorders.
THERMOGENESIS  CORP.  has entered  into a period of rapid  transformation  as it
begins to manufacture and market micro-manufacturing  systems which may generate
recurring  revenues  from  the  ongoing  sale of high  margin  blood  processing
disposables.

THERMOGENESIS  CORP.'s  strategy  is to  utilize  its two new  Biopharmaceutical
Technology  Platforms - the BioArchive Platform and the CryoSealTM Platform - as
the   basis   for   developing   micro-   manufacturing   systems   to   produce
biopharmaceutical  drugs from either  autologous or single  directed donor blood
which  will  compete  in two major  medical  markets:  Wound  Care and  Cellular
Therapy.

THERMOGENESIS CORP. is incorporated in Delaware. THERMOGENESIS CORP.'s principal
executive  offices  are  located  at  3146  Gold  Camp  Drive,  Rancho  Cordova,
California 95670 and its telephone number is (916) 858-5100.

                                  Risk Factors

For a  discussion  of  considerations  relevant to an  investment  in the common
stock. See the section entitled "RISK FACTORS" beginning on page 5.


                                  The Offering

Common Stock Outstanding Before the Offering.........................18,930,685
Common Stock Offered by Selling Stockholders(a).......................5,677,700
Common Stock Outstanding After the Offering(a).......................24,608,385
Use of Proceeds........................................THERMOGENESIS CORP. will
                                                       not receive any proceeds
                                                       from the offering
Nasdaq SmallCap Symbol......................................................KOOL


(a)     Assumes that Series A preferred stock  shareholders  have converted such
        shares into  5,387,700  shares of common stock in the aggregate and that
        warrantholders  have exercised their warrants to purchase 290,000 shares
        of common stock in the aggregate.




<PAGE>5



                                  RISK FACTORS

An investment in our common stock involves a number of very  significant  risks.
Because of these risks,  only persons able to bear the risk of and withstand the
loss of their entire investment  should invest in the common stock.  Prospective
investors  should  also  consider  the  following  before  making an  investment
decision.

Recurring Losses.  Except for net income of $11,246 for fiscal 1994 on net sales
of $2,678,192,  THERMOGENESIS CORP. has not been profitable since its inception.
For the fiscal year ended June 30, 1998,  THERMOGENESIS  CORP. had a net loss of
$9,550,795 on net sales of $4,396,891,  and an  accumulated  deficit at June 30,
1998, of $20,739,545.  The report of independent  auditors on the Company's June
30, 1998,  financial  statements  includes an explanatory  paragraph  indicating
there is  substantial  doubt about the Company's  ability to continue as a going
concern. For the three months ended September 30, 1998, THEMOGENESIS CORP. had a
net loss of $1,804,494.

Dependence Upon New Products for Future Growth. Historically,  substantially all
of our sales  have been from  products  related  to the  freezing,  thawing  and
storing  of blood  plasma.  Because we expect  the blood  plasma  market to have
limited  growth,  new  products  for the  biotechnology  market  will have to be
developed  for future  growth.  THEMOGENESIS  CORP.  is  currently  focusing  on
developing  thermodynamic  blood  processing  systems  such as: (1) a system for
processing  cryoprecipitated AHF utilizing a thermodynamic device and disposable
processing containers  ("CryoSeal(TM) System"); and (2) a system for collecting,
processing,  controlled-rate  freezing and inventory  management of thermolabile
products in liquid nitrogen utilizing disposable  containers ("N2 BioArchive(TM)
System").  See "Annual  Report on Form 10-K -- The Company."  Although these two
products use  technology  related to the freezing,  thawing and storage of blood
plasma, these products represent a departure from THERMOGENESIS  CORP.'s current
core blood  plasma  business.  Further,  although  THERMOGENESIS  CORP.  has had
discussions  with  experts in areas of  application  for these  products,  these
products are still in their development and initial market phase.  THERMOGENESIS
CORP. has not yet had significant sales for these products.  No assurance can be
given that all of these potential products can be successfully developed, and if
developed, that a market will also develop for them.

Government  Regulation  of  Products.  Most of  THERMOGENESIS  CORP.'s  products
require FDA  clearance to sell in the U.S.  Further,  THERMOGENESIS  CORP.  will
require  approval  from  comparable  agencies  to sell its  products  in foreign
countries.  These  approvals  may  limit  the U.S.  or  foreign  market in which
THERMOGENESIS CORP.  products may be sold or circumscribe  applications for U.S.
or foreign markets in which THERMOGENESIS CORP.'s products may be sold. Further,
if  THERMOGENESIS  CORP.  cannot  establish that its products are  substantially
equivalent,  or superior, in safety and efficacy to previously approved products
in the U. S.,  delays may result in final  clearance  from the FDA for marketing
its  products.  No  assurance  can be given  that the FDA  clearance  to  market
THERMOGENESIS CORP.'s products in the U. S. will be obtained, or that regulatory
approval  will be received  in all foreign  countries.  Although  the  standards
established by the FDA are generally more  encompassing,  THERMOGENESIS  CORP.'s
products  may also be required to meet  certain  additional  criteria or receive
certain approvals from other foreign governments for marketing and sales.


<PAGE>6



Influence of Governmental  and Insurance  Companies on Sales of Products Made by
THERMOGENESIS CORP. THERMOGENESIS CORP.'s business may be materially affected by
continuing  efforts by  government  and third  party  payors  such as  medicare,
medicaid,  private health insurance plans to reduce the costs of healthcare. For
example,  in certain  foreign  markets the pricing and profit margins of certain
healthcare   products  are  subject  to  government   controls.   In  the  U.S.,
THEMOGENESIS  CORP.  expects that there will  continue to be a number of federal
and state  proposals  to  implement  similar  government  control.  In addition,
increasing  emphasis on managed care in the U.S. will continue to place pressure
on the pricing of healthcare products. As a result, continuing effort to contain
healthcare   costs  may  result  in  reduced  sales  or  price   reductions  for
THERMOGENESIS CORP.'s products.

Inability to Protect Our Patents,  Trademarks and Other Proprietary Rights Could
Adversely  Impact  Our  Competitive  Position.  We  believe  that  our  patents,
trademarks  and other  proprietary  rights are  important to our success and our
competitive  position.  Accordingly,  we  devote  substantial  resources  to the
establishment and protection of our patents,  trademarks and proprietary rights.
We currently hold patents for products,  and have patents pending for additional
products,  that we market or intend to market. However, our actions to establish
and  protect  our  patents,  trademarks  and  other  proprietary  rights  may be
inadequate to prevent  imitation of our products by others or to prevent  others
from claiming  violations of their  trademarks and proprietary  rights by us. If
our products are challenged as infringing upon patents of other parties, we will
be  required to modify the design of the  product,  obtain a license or litigate
the issue,  all of which may have an adverse  business  effect on  THERMOGENESIS
CORP.

Trade  Secrets.  We use various  methods,  including the use of  confidentiality
agreements with employees,  vendors and customers,  to protect our trade secrets
and proprietary know-how for our products. However, such methods may not provide
complete  protection  and there can be no assurance  that others will not obtain
THERMOGENESIS  CORP.'s  know-how,  or independently  develop the same or similar
technology.

Competition. THERMOGENESIS CORP. hopes to develop a competitive advantage in the
medical  applications of its products,  but there are many  competitors that are
substantially  larger and possess greater financial resources and personnel than
THERMOGENESIS CORP.  THERMOGENESIS CORP.'s current principal market is the users
of  ultra-rapid  blood  plasma  freezing and thawing  equipment.  There are four
companies  which sell freezers to the blood plasma  freezing  industry which are
larger and possess  greater  financial and other  resources  than  THERMOGENESIS
CORP. The CryoSeal System may face competition  from major plasma  fractionaters
which  currently  sell fibrin glue sourced from pooled plasma  outside the U. S.
With  regard to the  BioArchive  System,  numerous  larger and  better  financed
medical device manufacturers may choose to enter this market as it develops.

Limited  Marketing  and  Sales  Force  for  New  Products.  THERMOGENESIS  CORP.
currently  sells its existing Class I medical devices through a direct sales and
marketing  force.  Although  THERMOGENESIS  CORP. has entered into  distribution
agreements for the area of the two new platform products there are no assurances
that the distributors will produce significant sales of the systems.

Lack of Production  Experience for New Products.  THERMOGENESIS CORP.  currently
manufactures  its Class I medical  devices - blood plasma  thawers and freezers.



                                                

<PAGE>7



Although  THERMOGENESIS  CORP.  has  redesigned  its  manufacturing  facility to
accommodate the BioArchive System and the CryoSeal System,  THERMOGENESIS  CORP.
does not have  significant  experience  in  manufacturing  more complex Class II
medical devices such as the BioArchive  System and the CryoSeal System or in the
manufacture  of  disposables.  Furthermore,  there  can  be  no  assurance  that
THERMOGENESIS CORP.'s current resources and manufacturing  facility could handle
a  significant  increase  in orders  for  either  the  BioArchive  System or the
CryoSeal System.  If  THERMOGENESIS  CORP. is unable to meet demand for sales of
the new systems,  it would need to contract with third-party  manufacturers  for
the backlog,  and no assurances can be made that such third-party  manufacturers
can be retained,  or retained on terms favorable to THERMOGENESIS  CORP. and its
pricing of the  equipment.  Inability  to have  products  manufactured  by third
parties at a competitive price will erode anticipated margins for such products,
and negatively impact profitability.

No Assurance of New Product  Acceptance.  The market acceptance of THERMOGENESIS
CORP.'s new products in development  will depend upon the medical  community and
third-party  payers  accepting  the  products as  clinically  useful,  reliable,
accurate  and cost  effective  compared  to  existing  and  future  products  or
procedures.  Market acceptance will also depend on THERMOGENESIS CORP.'s ability
to  adequately  train  technicians  on how to use the  CryoSeal  System  and the
BioArchive System. Even if THERMOGENESIS CORP.'s systems are clinically adopted,
the use may not be  recommended  by the medical  profession or hospitals  unless
acceptable  reimbursement  from health care and third-party payers is available.
Failure of either of these new systems to achieve significant market share could
have  material  adverse  effects on  THERMOGENESIS  CORP.'s long term  business,
financial condition and results of operation. See "Annual Report on Form 10-K --
Description  of  Business"  and  "Risk  Factors  --  Uncertain  Availability  of
Third-Party Reimbursement."

There is No  Assurance  That Our Senior  Management  Team Will  Remain  With Us.
THERMOGENESIS  CORP. is dependent  upon the experience and services of Philip H.
Coelho, Chairman and Chief Executive Officer, and James H. Godsey, President and
Chief  Operating  Officer.  The loss of either  person  would  adversely  affect
THERMOGENESIS CORP.'s operations.  THERMOGENESIS CORP. has obtained key man life
insurance  covering Mr. Coelho in the amount of  $1,000,000  as some  protection
against this risk. See "Annual Report on Form 10-K -- Employees."

Product  Liability and Uninsured  Risks. We may be liable if any of our products
causes  injury,  illness or death.  We also may be required to recall certain of
our products  should they become  damaged or if they are  defective.  We are not
aware of any material product  liability claim against us. Further we maintain a
general liability policy which includes product liability coverage of $1,000,000
per occurrence and  $2,000,000  per year in the  aggregate.  However,  a product
liability claim against us could have a material  adverse effect on our business
or financial condition.

Risk of Software  Defects.  Our CryoSeal  System and  BioArchive  System rely on
computer software  components that direct the harvesting process of the CryoSeal
System, and the controlled-rate freezing,  storage and retrieval robotics of the
BioArchive  System.  The software program for these products,  including updated
versions  in the future,  may contain  undetected  errors or  failures.  Despite
testing by the Company and customers, there can be no assurance that errors will
not be found in the software during continuous use. Unfound errors may result in
loss or delay in market acceptance,  which could have an adverse material effect
on the Company's business, financial condition and results of operations.



<PAGE>8



Future  Sales of  Unregistered  Shares  Could Have A Negative  Impact on Trading
Price of the Common Stock. Under an agreement with the selling stockholders,  we
have agreed to register for resale by this prospectus  shares of common stock to
be issued  upon the  conversion  of the  Series A  preferred  stock and upon the
exercise of the  warrants.  The number of shares of common stock  available  for
resale by this  prospectus  represents  approximately  30% of our  common  stock
outstanding.  Because the trading  price for our common stock may be affected by
the number of shares  available  for resale,  the market price of  THERMOGENESIS
CORP.  common  stock could drop as a result of sales of a large number of shares
of THERMOGENESIS  CORP.  common stock in the market after this offering,  or the
perception that such sales could occur.

Possible Need for Additional Financing.  Based on proceeds of approximately $6.5
million  received in  THERMOGENESIS  CORP.'s most recent private  placement,  we
believe  we will  have  sufficient  working  capital  for our 1999  fiscal  year
operations.  However, if actual sales do not meet expectations, or marketing and
production  costs increase  significantly,  we may need additional  financing to
complete and implement  our business  objectives.  Further,  delays in obtaining
required governmental approvals to, or additional testing requirements prior to,
marketing our new products will result in decreased revenues and increased costs
that may require THERMOGENESIS CORP. to seek additional financing. THERMOGENESIS
CORP.  is  attempting  to obtain a bank line of credit  secured by its  accounts
receivable.  However,  we  cannot  guarantee  that we will be able to  obtain  a
working  line  of  credit.  In the  event  that  there  is a cash  shortage  and
THERMOGENESIS CORP. is unable to obtain a bank loan, additional equity financing
will be  required  which  will have the  effect of  diluting  the  ownership  of
existing shareholders.

No Cash Dividends.  To date, we have not paid any cash dividends,  and we do not
expect to pay any cash on our common stock in the foreseeable future.



<PAGE>9



                          SUMMARY FINANCIAL INFORMATION

The  following  summary  information  is derived from the  financial  statements
included in THERMOGENESIS  CORP.'s Annual Report on Form 10-K for the year ended
June 30, 1998, and Quarterly Report on Form 10-Q for the quarter ended September
30, 1998,  incorporated by reference  herein,  and should be read in conjunction
with those financial statements and the related notes thereto:

<TABLE>

<S>                                <C>           <C>               <C>          <C>           <C>    

                                                                                 For the Three Months
                                        For the Year Ended June 30,              Ended September 30,
                                        ---------------------------              ---------------------
                                      1996           1997            1998           1997          1998
                                   -----------  -------------    -----------   -----------   -------------
Statement of Operations Data:
Revenues                          $ 4,124,634   $  6,614,044    $  4,396,891    $   711,100    $  1,098,683
Operating expenses                $ 3,018,356   $  7,207,274    $  8,493,699    $ 2,109,332    $  1,642,407
Net loss                          $  (568,534)  $ (4,805,822)   $ (9,550,795)   $(2,461,928)   $ (1,804,494)
Net loss per common share         $     (0.05)  $      (0.32)         $(0.54)   $     (0.16)   $      (0.10)
Weighted average shares            11,491,000     14,805,000       7,629,876     15,872,388      18,925,669
outstanding

</TABLE>

<TABLE>

<S>                                     <C>           <C>              <C>                 <C>
                                              June 30,                      September 30,
                                              --------                      -------------
                                           1997            1998           1997             1998
                                       ------------    -----------    -----------      ------------
Selected Balance Sheet Data:
Working Capital                        $ 6,407,237      $3,723,317     $3,947,112        $2,039,959
Total Assets                           $10,187,726      $7,799,242     $7,918,430        $5,943,760
Long Term Obligations                  $   164,283      $   57,519     $  136,975        $   52,544
Total Liabilities                      $ 2,163,084      $2,226,350     $2,286,841        $2,164,362
Stockholders' Equity                   $ 8,024,642      $5,572,892     $5,631,589        $3,779,398

</TABLE>


<PAGE>10



                                   THE COMPANY

THERMOGENESIS  CORP.  designs and sells  products and devices  which utilize its
proprietary thermodynamic technology for the processing of biological substances
including  the  cryopreservation,  thawing,  harvesting  and  archiving of blood
components. Historically,  THERMOGENESIS CORP.'s primary revenues have been from
sales of blood plasma  freezers and thawers to hospitals,  blood banks and blood
transfusion  centers.  Currently,  THERMOGENESIS CORP. is manufacturing  several
categories  of  thermodynamic  devices  which are being sold to the blood plasma
industry  under FDA clearance to market in the United  States.  Other  potential
markets for  THERMOGENESIS  CORP.'s  proprietary  technology  include  surgical,
pharmaceutical,   and   industrial   applications.   Since   fiscal  year  1988,
THERMOGENESIS  CORP.  focused  its  efforts  on  research  and  development  and
refinement  of a core line of  products  for blood  banks.  Since  fiscal  1994,
THERMOGENESIS  CORP.  has  developed  new  applications  for  its  products  and
technology,  including  a  system  for  harvesting  cryoprecipitated  AHF from a
donor's  blood  plasma  for  use in the  treatment  of  hemophilia,  and by some
physicians  as a  hemostatic  agent or tissue  sealant in certain  surgical  and
medical procedures.

THERMOGENESIS  CORP.'s strategy was to develop superior blood processing devices
for the  niche  blood  processing  markets  where  new  products  could  quickly
establish   credibility  for  THERMOGENESIS   CORP.'s  Proprietary   Technology.
THERMOGENESIS  CORP.  believed that by  concentrating  its products to serve the
blood  plasma  industry,  many  customers,  such as the Red Cross or other blood
transfusion societies of various countries, would validate THERMOGENESIS CORP.'s
Proprietary  Technology  for  rapid  freezing  of  biological  substances,  more
specifically  blood plasma.  Early  products which were designed for blood banks
and hospitals,  have received  510(k)  permission to market,  and  THERMOGENESIS
CORP.  sells  either  directly  or through  its  distribution  network in the 32
countries where its products are marketed. See "Annual Report on Form 10-K."

From 1988 to 1992 THERMOGENESIS  CORP.'s products were designed to transfer heat
by causing heat transfer liquids to directly  contact plastic sealed  containers
within which  resided  various  blood  components.  Early  product  designs used
liquids  containing  chloro-flouro-carbons  ("CFC")  which  THERMOGENESIS  CORP.
phased out in the fall of 1992.  Thereafter,  THERMOGENESIS  CORP.  developed an
alternative heat transfer method which automatically  interposed a thin flexible
membrane  between  the heat  transfer  liquid and  biological  substances  which
process allowed for use of non-CFC based heat transfer liquids.

Principal  products initially  developed by THERMOGENESIS  CORP. and marketed to
hospitals,  blood banks, and blood transfusion centers consisted of freezers and
thawers for blood plasma.  THERMOGENESIS  CORP.  continued to design and develop
various freezer models and thawers for expanded applications, and these products
remain the core products of THERMOGENESIS  CORP.'s current  business.  To expand
its  market  and  product  use,  THERMOGENESIS  CORP.  changed  the focus of its
research and  development to the design of new products that would be applied to
different   applications   within  the  blood  industry,   including   surgical,
pharmaceutical   and  medical  procedures  that  utilize  freezing  and  thawing
technology as part of standard procedures. See "Annual Report on Form 10-K."


<PAGE>11



Recent Financing and Other Recent Events

In November 1998, THERMOGENESIS CORP. experienced a short-term cash shortage and
borrowed  $450,000 in the  aggregate  from  lenders,  including  $200,000 in the
aggregate from three directors of THERMOGENESIS CORP. The loans bear interest of
10% per annum, are secured  substantially by all of THERMOGENESIS CORP.'s assets
and mature on May 19,  1999.  In  addition,  the  lenders  received  warrants to
purchase  90,000 shares of common stock in the aggregate at $1.50 per share.  In
connection with the Series A preferred stock private placement,  $300,000 of the
debt was exchanged for 48,000 shares of Series A preferred  stock. The remaining
$150,000 plus interest has been repaid.

On December 11, 1998,  THERMOGENESIS  CORP.'s shareholders approved an amendment
to its  Certificate  of  Incorporation  to effect a  one-for-four  reverse stock
split. The Board is currently determining the most appropriate time to implement
the reverse stock split.

On January  14,  1999,  THERMOGENESIS  CORP.  completed a private  placement  of
1,077,540  shares  of  Series  A  Preferred  Stock,   raising  an  aggregate  of
$6,734,625,  before  commissions and direct  expenses.  Commissions of 7% of the
gross proceeds and warrants to purchase  200,000 shares of common stock at $1.70
per share  were  issued to the  placement  agent.  An  initial  closing  for the
preferred stock was held on December 31, 1998, with gross proceeds of $5,100,000
having been received.  The net proceeds from the private  placement will be used
for clinical trials of the CryoSeal Autologous Fibrin Glue System and CryoFactor
Autologous Platelet Derived Growth Factor System through an independent clinical
research organization, repayment of short-term debt and working capital.

The value assigned to the beneficial conversion feature, as determined using the
quoted  market  price of the  Company's  common  stock on the date the  Series A
preferred  stock was sold,  amounted to  $2,297,040  on December 30,  1998,  and
$1,307,700 on January 14, 1999,  which represents a discount to the value of the
Series A preferred stock.


                             SUMMARY OF THE OFFERING

THERMOGENESIS  CORP. is registering  5,677,700 shares of common stock for resale
by the selling stockholders of which 5,387,700 may be issued upon the conversion
of Series A preferred  stock and 290,000  shares may be issued upon the exercise
of warrants,  including  warrants to purchase  200,000 shares as placement agent
warrants.


                                 USE OF PROCEEDS

THERMOGENESIS  CORP.  will receive no proceeds  from the resale of the shares of
common stock upon the  conversion of the Series A preferred  stock and resale of
the shares of common stock upon the exercise of the warrants.



<PAGE>12



                              SELLING STOCKHOLDERS

The following table identifies the Selling Stockholders, as of February 5, 1999,
and indicates certain  information known to THERMOGENESIS  CORP. with respect to
(i) any material relationship between the selling stockholders and THERMOGENESIS
CORP.  during the past three  years,  (ii) the number of shares of common  stock
held by the selling stockholders, (iii) the amount to be offered for the selling
stockholders'  account,  and  (iv)  the  number  of  shares  and  percentage  of
outstanding shares of common stock to be owned by the selling stockholders after
the sale of the common stock offered by the selling stockholders.  To the extent
required under the federal securities laws, this prospectus may be also used for
resale of common stock upon the  conversion of the Series A preferred  stock and
the exercise of the warrants. The selling stockholders are not obligated to sell
their common stock offered by this prospectus.

The table assumes that the selling  stockholders  have converted  their Series A
preferred  stock or exercised their warrants and will sell the common stock in a
secondary offering pursuant to this prospectus.

Under the Exchange Act, any person  engaged in a  distribution  of the shares of
common  stock  of  THERMOGENESIS  CORP.  offered  by  this  prospectus  may  not
simultaneously  engage in market  making  activities  with respect to the common
stock  of  THERMOGENESIS  CORP.  during  the  applicable  periods  prior  to the
commencement  of such  distribution.  In  addition,  and  without  limiting  the
foregoing,  each selling stockholder may be subject to applicable  provisions of
the Exchange Act and the rules and  regulations  thereunder  including,  without
limitation  Regulation M.  Further,  the selling  shareholders  may resell their
shares pursuant to Rule 144.

The Series A  preferred  stock and  warrants  are not  registered  or listed for
trading on the Nasdaq Stock Market or on any exchange. With regard to the shares
of common stock offered by the selling  stockholders for resale, such shares may
be sold on the Nasdaq  Stock Market or in private  transactions  at prices to be
determined   at  the  time  of  sale.   Such  shares  may  be  offered   through
broker-dealers,  acting on the selling  stockholders'  behalf, who may offer the
shares at then  current  market  prices.  Any sales may be by block  trade.  The
selling stockholders and any brokers, dealers or others who participate with the
selling  stockholders in the  distribution of such shares of common stock may be
deemed to be  "underwriters"  within the meaning of the Securities  Act, and any
commissions  or fees  received  by such  persons and any profit on the resale of
such  shares  purchased  by  such  persons  may  be  deemed  to be  underwriting
commissions  or discounts  under the  Securities  Act.  Sales may be made by all
selling  stockholders  pursuant  to the  registration  statement  of which  this
prospectus is a part.

<TABLE>

<S>                                        <C>           <C>           <C>           <C>        <C>   

                                           Shares Beneficially Owned  Shares to be    Shares Beneficially
                                               Prior to Offering          Sold        Owned After Offering
                                               ------------------         ----        ---------------------
Name of Shareholder                         Number      Percentage     Number       Number     Percentage
- -------------------                      -----------    ----------   -------------  ------     ----------
The Kaufmann Fund, Inc.                    3,760,000(2)               2,880,000(1)
Clarion Capital Corporation                  240,000(1)                 240,000(1)
Bradley Resources Company                    210,000(3)                 160,000(1)

</TABLE>



<PAGE>13
<TABLE>

<S>                                          <C>                        <C>           <C>         <C>    


                                           Shares Beneficially Owned  Shares to be    Shares Beneficially
                                               Prior to Offering          Sold         Owned After Offering
                                           -------------------------  ------------    ---------------------
                                                Number      Percentages     Number        Number     Percentages  
                                             -----------   -----------    ---------    -------    -------------                
Pequot Scout Fund, L.P.                        400,000(1)                 400,000(1)
Atlas II, L.P.                                 336,000(1)                 336,000(1)
RJ Capital, L.P.                                64,000(1)                  64,000(1)
Philip H. Coelho TTEE Coelho Living Trust                                                                    
Chief Executive Officer                                                                                      
3146 Gold Camp Drive                           650,500(4)                  60,000(5)
Rancho Cordova, CA 95670
New England Venture Partners                   250,000(6)                 250,000(6)
Carol Jacinto                                    8,000(1)                   8,000(1)
Veron International Limited                  1,150,000(7)                 400,000(1)
Victor S. Lee                                  160,000(1)                 160,000(1)
Hung Kwong International Ltd.                   80,000(1)                  80,000(1)
Choy Man Kin                                    40,000(1)                  40,000(1)
BioTechnology Development Fund, LP             466,465(1)                  66,465(1)
BioTechnology Development Fund III, LP          33,235(1)                  33,235(1)
Hofung Holdings Limited                         80,000(1)                  80,000(1)
Judy Yee-Yong Ling                              40,000(1)                  40,000(1)
Xinjiang Commercial Managed Fund                40,000(1)                  40,000(1)
Mark Sater TTEE Vigevano Retirement                                   
Benefit Scheme 1992                             20,000(1)                  20,000(1)
Charles W. Chambers & Roberta Chambers
JT TEN                                         100,000(1)                 100,000(1)
Hubert Huckel                                                                                                
Director                                                                                                     
3146 Gold Camp Drive                            50,000(8)                  10,000(9)
Rancho Cordova, CA 95670
Patrick McEnany                                                                                              
Director                                                                                                     
3146 Gold Camp Drive                          115,829(10)                  10,000(9)
Rancho Cordova, CA 95670
Oscar Gruss & Son                             200,000(11)                 200,000(11)
</TABLE>

<PAGE>14


Footnotes to Table

 *      Less than one percent.

(1)     Represents  the number of shares of common stock upon  conversion of the
        Series A preferred  stock based on a conversion  ratio of five shares of
        common stock for each share of Series A preferred stock.

(2)     Includes  warrants  to  purchase  80,000  shares  of  common  stock  and
        2,880,000 shares of common stock to be issued assuming the conversion of
        576,000 shares of Series A preferred stock.

(3)     Includes  warrants to purchase 10,000 shares of common stock and 160,000
        shares of common stock to be issued  assuming the  conversion  of 32,000
        shares of Series A preferred stock.

(4)     Includes options to purchase 425,000 shares of common stock owned by Mr.
        Coelho,  warrants to purchase 20,000 shares of common stock,  and 40,000
        shares of common  stock to be issued  assuming the  conversion  of 8,000
        shares of Series A preferred stock.

(5)     Includes  warrants to purchase  20,000 shares of common stock and 40,000
        shares of common  stock to be issued  assuming the  conversion  of 8,000
        shares of Series A preferred stock.

(6)     Includes  warrants to purchase 50,000 shares of common stock and 200,000
        shares of common stock to be issued  assuming the  conversion  of 40,000
        shares of Series A preferred stock.

(7)     Includes warrants to purchase 250,000 shares of common stock and 400,000
        shares of common stock to be issued upon the conversion of 80,000 shares
        of Series A preferred stock.

(8)     Includes warrants to purchase 10,000 shares of common stock and options 
        to purchase 40,000 shares of common stock.

(9)     Represents  shares of common  stock  subject to resale upon the exercise
        of warrants.

(10)    Includes warrants to purchase 10,000 shares of common stock, and options
        to purchase  40,000 shares of common stock.  Also includes 25,829 shares
        owned by Equisource Capital of which Mr. McEnany is the sole shareholder
        and  2,500  owned  by  Mr.  McEnany's  spouse.   Mr.  McEnany  disclaims
        beneficial ownership of the shares owned by his spouse.

(11)    Represents shares of common stock subject to resale upon the exercise of
        a warrant issued to the Placement Agent.


                            DESCRIPTION OF SECURITIES

Our  authorized  capital  stock  consists  of  two  classes  which  consists  of
50,000,000 shares,  $.001 par value, of common stock and 2,000,000 shares, $.001
par value,  of preferred  stock.  As of February 5, 1999,  18,930,685  shares of
common stock were  outstanding and 1,029,540  shares of Series A preferred stock
were outstanding. There are no other series of preferred stock outstanding.




<PAGE>15

Common Stock


Common stock  shareholders have full voting rights, one vote for each share held
of  record.   Subject  to  preferential  rights  of  Series  A  Preferred  Stock
shareholders   and  any  other   preferred  stock   shareholder,   common  stock
shareholders  are entitled to receive  dividends as may be declared by the Board
out of funds legally available therefor, and share pro rata in any distributions
to stockholders upon liquidation.  Common stock shareholders have no conversion,
preemptive or other subscription rights. All of the outstanding shares of common
stock are, and the shares offered hereby will be, validly issued, fully paid and
nonassessable.



<PAGE>16



Preferred Stock

As discussed below, we have one series of preferred stock designated.  The Board
is authorized to establish,  other series or designation of preferred stock with
rights, preferences, privileges, and restrictions on such stock as the Board may
determine.

Series A Convertible Redeemable Preferred Stock

We have designated 1,200,000 shares as Series A convertible redeemable preferred
stock. Each share of Series A preferred stock has the following characteristics:

Conversion.  Each Series A preferred  stock is  convertible  into five shares of
common stock at the option of holder or at THERMOGENESIS CORP.'s option provided
that the common  stock is trading at an average  price equal to or greater  than
$5.00 per share for 30 consecutive  trading days.  Each Series A preferred stock
is subject to customary anti-dilution protection.

Voting  Rights.  Provided that more than 35% of the number of Series A preferred
stock  shares sold in the private  placement  remain  outstanding,  the Series A
preferred  stock  shareholder  will be  entitled  to vote for one  director,  as
separate  class,  and approval by holders of at least a majority of the Series A
preferred  stock,  voting  together as a separate class, is required for certain
events  including  (i) any  issuance  of a new series of shares  having  rights,
preferences, or privileges with respect to liquidation preference, redemption or
dividend rights senior or equivalent to the Series A preferred  stock,  (ii) any
payment or  declaration  of any dividends  rights or any other  distribution  or
redemption  of  any  capital  stock  of  THERMOGENESIS   CORP.,  (iii)  sale  or
disposition of substantially  all of THERMOGENESIS  CORP.'s property or business
or any consolidation or merger with any entity in which  THERMOGENESIS  CORP. is
not the  survivor,  (iv) an  amendment  to  THERMOGENESIS  CORP.'s  articles  of
incorporation or bylaws,  and (v) any investments of another business  exceeding
$1 million in the  aggregate.  Unless  required  by law,  the Series A preferred
stock shareholders will be entitled to vote on all other matters with the common
stock shareholders, together as a class, on an as converted basis.

Dividends.  Each Series A preferred stock is entitled to receive  non-cumulative
dividends  at the  same  rate  and  same  time  as  any  dividends  declared  on
THERMOGENESIS CORP. common stock determined on an as converted basis.

Liquidation   Rights.   Upon   liquidation,   dissolution,   or  winding  up  of
THERMOGENESIS  CORP.,  the  holder of each  Series A  Preferred  Stock  shall be
entitled to  received a  liquidation  preference  equal to $6.25 per share which
shall  increase at the rate of 8% per share,  per year,  compounded  annually on
each  anniversary  date of the  issuance of the Series A preferred  stock before
there are any  distributions  to common  stock  shareholders.  After  payment to
Series A preferred stock of the liquidation preference as adjusted, the Series A
preferred stock shareholder  shall not be entitled to any further  distribution.
If upon any liquidation, dissolution or winding up, the assets to be distributed
among the Series A preferred stock  shareholder  shall be insufficient  for full
payment of the liquidation  preference,  then the amount to be distributed shall
be  distributed  ratably to the Series A preferred  stock  shareholders  and any
other preferred stock of equal rank.


<PAGE>17



Redemption.  After five years,  Series A preferred stock  shareholders will have
the right to require  THERMOGENESIS  CORP. to  repurchase  from such holder each
Series A preferred stock for the liquidation preference as adjusted.

Preemptive  Rights.  Each  Series  A  preferred  stock  shareholder  shall  have
preemptive  rights to purchase any new issue by THERMOGENESIS  CORP. in order to
maintain such ownership interest in THERMOGENESIS CORP.

Options

As of January 15, 1999,  THERMOGENESIS CORP. had outstanding options to purchase
a total of  1,613,450  shares of common  stock at exercise  prices  ranging from
$1.64  to  $4.50  per  share,  of  which  options  to  purchase  1,240,193  were
exercisable.  Some of these options are subject to vesting, and in general, have
a three or five year exercise  period.  See "Annual Report on Form 10-K -- Notes
to Financial Statements."

Warrants

As of January 15,  1999,  warrants to  purchase a total of  2,524,201  shares of
common stock were  outstanding with exercise prices ranging from $2.40 to $3.885
per share, all of which were exercisable. Included in the number of warrants are
warrants to purchase  290,000 shares of common stock which are subject to resale
by this  prospectus.  See  "Annual  Report  on Form  10-K -- Notes to  Financial
Statements."

Registration Obligation

THERMOGENESIS CORP. has agreed to register for resale the shares of common stock
upon the  conversion  of the Series A  preferred  stock and the  exercise of the
warrants.  In the event the  registration  statement  registering for resale the
shares of common  stock is not declared  effective  within 120 days from January
14,  1999,  which is the closing  date of the private  placement of the Series A
preferred  stock,  the aggregate  number of shares of common stock issuable upon
the conversion of the Series A preferred stock shall be increased by 5% for each
additional 30 days the registration statement is not declared effective.


                     CERTIFICATE OF INCORPORATION AND BYLAWS

Our Amended and  Restated  Certificate  of  Incorporation  provide  that we will
indemnify  directors and officers of  THERMOGENESIS  CORP. to the fullest extent
permitted  by  Delaware  Law.   Further,   our  bylaws  provide   authority  for
THERMOGENESIS  CORP.  to maintain a liability  insurance  policy  which  insures
directors  or  officers  against  any  liability  incurred  by them  in  serving
THERMOGENESIS CORP.

Insofar as indemnification  for liabilities arising under the Securities Act may
be permitted to directors,  officers and  controlling  persons of  THERMOGENESIS
CORP. pursuant to the foregoing  provisions,  or otherwise,  THERMOGENESIS CORP.
has been advised that in the opinion of the Commission such


<PAGE>18



indemnification  is against public policy as expressed in the Securities Act and
is,  therefore,  unenforceable.  In the event  that a claim for  indemnification
against  such  liabilities  (other than the payment by  THERMOGENESIS  CORP.  of
expenses  incurred  or paid by a  director,  officer  or  controlling  person of
THERMOGENESIS CORP. in the successful defense of any action, suit or proceeding)
is asserted by such director,  officer or controlling  person in connection with
the securities being registered, THERMOGENESIS CORP. will, unless in the opinion
of its counsel the matter has been settled by controlling precedent, submit to a
court of appropriate  jurisdiction the question whether such  indemnification by
it is against  public  policy as  expressed  in the Act and will be  governed by
final adjudication.


                                 TRANSFER AGENT

The transfer agent for our common stock is American Securities Transfer & Trust,
Inc., 938 Quail Street, Suite 101, Lakewood, Colorado 80215-5513.


                                     EXPERTS

The  financial  statements of  THERMOGENESIS  CORP.  appearing in  THERMOGENESIS
CORP.'s  Annual  Report (Form 10-K) for the year ended June 30, 1998,  have been
audited by Ernst & Young LLP, independent auditors, as set forth in their report
thereon (which contain an explanatory paragraph describing conditions that raise
substantial  doubt about the Company's ability to continue as a going concern as
described  in  Note  1  to  the  financial   statements)  included  therein  and
incorporated  herein by reference.  Such financial  statements are  incorporated
herein by  reference in reliance  upon such report  given upon the  authority of
such firm as experts in accounting and auditing.


                                  LEGAL MATTERS

The validity of the shares of common stock  offered by the selling  stockholders
through this  prospectus  will be passed upon for us by David C. Adams,  General
Counsel and Vice President of Business Development. Mr. Adams beneficially owned
options to acquire 120,000 shares of common stock as of February 5, 1999.



<PAGE>19



                                    GLOSSARY OF CERTAIN TECHNICAL TERMS


510(k):  formal  notification  to the Food and Drug  Administration  ("FDA")  by
manufacturers  of Class I or Class II devices to obtain  clearance to market the
medical  device.  The  device  must  be  substantially   equivalent  to  devices
manufactured prior to 1976.

AUTOLOGOUS:  autogenous; related to self; originating within an organism itself,
as an autograft or autotransfusion.

CLASS II MEDICAL  SYSTEM:  those  devices for which general  controls  alone are
insufficient  to  assure  safety  and  effectiveness  and  for  which  mandatory
performance standards must be developed by the FDA.

COAGULATION:  (1) the process of clot formation;  (2) in surgery, the disruption
of  tissue  by   physical   means  to  form  an   amorphous   residuum,   as  in
electrocoagulation and photocoagulation.

CORE LINE PRODUCTS:  (1) device for the  ultra-rapid  cryopreservation  of human
blood plasma; (2) portable device for the ultra-rapid  cryopreservation of human
blood  plasma;  (3) device for the rapid  thawing of frozen  plasma for hospital
patient care;  (4) device for the hermetic  sealing of blood tissue  containers;
(5) "smart"  blood  collection  monitor;  (6) Vial  BioArchiveTM  System for the
Japanese Red Cross.

CRYOPRECIPITATE:  any precipitate that results from cooling,  as cryoglobulin or
antihemophilic factor.

CRYOPRECIPITATED AHF: A preparation of antihemophilic  factor, which is obtained
from a single unit of plasma collected and processed in a closed system.

CRYOPRESERVATION:  the  maintaining of the viability of excised tissue or organs
by storing at very low temperatures.

CRYOSEALTM: system for harvesting fibrinogen-rich cryoprecipitate from a donor's
blood plasma,  a blood  component that is currently  licensed by the FDA for the
treatment of clotting protein deficient patients.

DEWAR:  container  which keeps its  contents  at a constant  and  generally  low
temperature by means of two external walls between which a vacuum is maintained.

FACTOR VIII:  antihemophilic  factor (AHF): a relatively  storage-labile  factor
participating only in the intrinsic pathway of blood coagulation.  Deficiency of
this factor, when transmitted as a sex-linked  recessive trait, causes classical
hemophilia  (hemophilia A). More than one molecular form of this factor has been
discovered.  Called also antihemophilic globulin (AHG) and antihemophilic factor
A.

FACTOR XIII: fibrin  stabilizing  factor (FSF): a factor that polymerizes fibrin
monomers so that they become stable and insoluble in urea,  thus enabling fibrin
to form a firm blood clot. Deficiency of this


<PAGE>20

factor  produces a clinical  hemorrhagic  diathesis.  Called also  fibrinase and
Laki-Lorand factor (LLF). The inactive form is also known as protransglutaminase
and the active form as transglutaminase.

FIBRONECTIN: an adhesive glycoprotein:  one form circulates in plasma, acting as
an opsonin;  another is a cell-surface  protein which mediates cellular adhesive
interactions.  Fibronectins  are  important  in  connective  tissue,  where they
cross-link to collagen, and they are also involved in aggregation of platelets.

HEMATOLOGY: that branch of medical science which treats of the morphology of the
blood and blood forming tissues.

HEMOSTATIC:  (1) checking the flow of blood;  (2) an agent that arrests the flow
of blood.

MACULAR:  pertaining to or characterized by the presence of macules;  pertaining
to the macula retinae.

N2 BIOARCHIVE:  system for controlled  rate freezing,  storage and retrieval and
inventory   management   of   biological   samples  which  require  LN2  storage
temperatures, such as placental, stem and progenitor cells.

PIPELINE  PRODUCTS:  (1) CryoSealTM  System,  thermodynamic  processor;  (2) LN2
BioArchiveTM  System,  computerized LN2 dewar with robotic arm; (3) CryoFactorTM
System,   thermodynamic   processor;   (4)  MicroSealantTM   System,  bench  top
thermodynamic processor; (5) CryoPlateletTM System, thermodynamic processor.

PLATELET  DERIVED  GROWTH  FACTOR  (PDGF):  a substance  contained  in the alpha
granules  of  platelets  and  capable  of  inducing  proliferation  of  vascular
endothelial cells, vascular smooth muscle cells, fibroblasts and glia cells; its
action contributes to the repair of damaged vascular walls.

PROGENITOR: a parent or ancestor.

THERMOLABILE:  easily altered or decomposed by heat.

VON WILLEBRAND'S FACTOR: the attribute of Factor VIII necessary for the adhesion
of  platelets to vascular  elements.  Deficiency  of this factor  results in the
prolonged bleeding time seen in von Willebrand's disease.



<PAGE>ii-1



                                     PART II

                     INFORMATION NOT REQUIRED IN PROSPECTUS

Item 14.  Other Expenses of Issuance and Distribution.

The following table sets forth the costs and expenses  payable by  THERMOGENESIS
CORP. in connection with the issuance and  distribution of the securities  being
registered  hereunder.  No expenses shall be borne by the Selling  Stockholders.
All of the amounts shown are estimates, except for the SEC Registration fee.


SEC registration fee                                    $ 4,396.67
Printing and engraving expenses                        *$
Accounting fees and expenses                           *$
Legal fees and expenses                                *$     -0-
Transfer agent and registrar fees                      *$
Fees and expenses for qualification under
   state securities laws                                   $  -0-
Miscellaneous                                             *$  -0-
                                                          ---------
TOTAL                                                      $        
                                                           =========

               *  estimated

Item 15.  Indemnification of Directors and Officers

Section 145 of the Delaware General  Corporation Law permits  indemnification of
directors,  officers and employees of corporations  under certain conditions and
subject to certain limitations.  Article Eighth of THERMOGENESIS CORP.'s Amended
and  Restated   Certificate  of   Incorporation   contain   provisions  for  the
indemnification of its directors and officers to the fullest extent permitted by
law.

Under such law, THERMOGENESIS CORP. is empowered to indemnify any person who was
or is a party or is threatened to be made a party to any proceeding  (other than
an action by or in the right of THERMOGENESIS CORP. to procure a judgment in its
favor) by reason of the fact that such  person is or was an  officer,  director,
employee or other agent of  THERMOGENESIS  CORP.  or its  subsidiaries,  against
expenses,   judgments,  fines,  settlements,  and  other  amounts  actually  and
reasonably incurred in connection with such proceeding,  if such person acted in
good faith and in a manner  such  person  reasonably  believed to be in the best
interests of THERMOGENESIS CORP. and, in the case of a criminal proceeding,  has
no  reasonable  cause to believe  the conduct of such  person was  unlawful.  In
addition,  THERMOGENESIS CORP. may indemnify, subject to certain exceptions, any
person  who  was or is a  party  or is  threatened  to be  made a  party  to any
threatened,  pending,  or completed  action by or in the right of  THERMOGENESIS
CORP.  to procure a judgment in its favor by reason of the fact that such person
is or was an officer,  director,  employee or other agent of THERMOGENESIS CORP.
or its subsidiaries,  against expenses actually and reasonably  incurred by such
person in  connection  with the  defense or  settlement  of such  action if such
person acted in good


<PAGE>ii-2



faith  and in a  manner  such  person  believed  to be in the best  interest  of
THERMOGENESIS  CORP.  and its  shareholders.  THERMOGENESIS  CORP.  may  advance
expenses  incurred in defending any proceeding  prior to final  disposition upon
receipt  of an  undertaking  by the  agent  to  repay  that  amount  it shall be
determined that the agent is not entitled to indemnification as authorized.

In  addition,   THERMOGENESIS  CORP.  has  director's  and  officer's  liability
insurance,  which THERMOGENESIS  CORP.'s bylaws provide authority to maintain to
insure directors or officers against any liability incurred capacity as such, or
arising out of their status as such.

Item 16.       Exhibits and Financial Statement Schedules
<TABLE>
<S>     <C>    <C>                                                                     <C>   

Exhibit        Description
3.1     (a)    Amended and Restated Certificate of Incorporation                       (4)
        (b)    Revised Bylaws                                                          (4)
4.1            Certificate of Designation Series A Convertible Redeemable
               Preferred Stock                                                        (12)
5.1            Opinion of David C. Adams, General Counsel to the registrant
10.1    (a)    Letter of Agreement with Liquid Carbonic, Inc.                          (1)
        (b)    Letter of Agreement with Fujitetsumo USA                                (1)
        (c)    Letter of Agreement with Fujitetsumo Japan                              (1)
        (d)    License Agreement between Stryker Corp. and
               THERMOGENESIS CORP., Corp.                                              (5)
        (e)    Lease of Office and Mfg. Space                                          (4)
        (f)    Executive Development and Distribution  Agreement
               between THERMOGENESIS CORP. and Daido Hoxan Inc.                        (3)
        (g)    Administrative Office Lease                                             (6)
        (h)    Employment Agreement for Philip H. Coelho                               (8)
        (i)    Employment Agreement for Charles de B. Griffiths                        (8)
        (j)    Employment Agreement for Walter J. Ludt                                 (8)
        (k)    Employment Agreement for David C. Adams                                (11)
        (l)    Employment Agreement for James H. Godsey                               (11)
        (m)    Employment Agreement for Sam Acosta                                    (11)
        (n)    Licensing/Manufacturing Agreement with On-Time Mfg.                     (8)
        (o)    License Agreement and distribution with Asahi Medical                   (9)
        (p)    License Agreement with Pall/Medsep Corporation                         (10)
        (q)    Distribution Agreement with Dideco S.P.A.                              (13)
</TABLE>


23.1           Consent of General Counsel is contained in exhibit 5.1.

23.2           Consent of Ernst & Young LLP, independent auditors

27.1           Financial Data Schedule (Not Applicable)


<PAGE>ii-3


Footnotes to Index 

(1) Incorporated  by  reference  to  Registration  Statement  No.  33-37242  of
    THERMOGENESIS CORP., Corp. filed on February 7, 1991.

(2) Incorporated by reference to Form 8-K for July 19, 1993.

(3) Incorporated by reference to Form 8-K for June 9, 1995.

(4) Incorporated by reference to Form 10-KSB for the year ended June 30, 1994.

(5) Incorporated by reference to Form 8-K for September 27, 1995.

(6) Incorporated by reference to Form 10-QSB for the quarter ended December 31,
    1995.

(7) Incorporated by reference to Form 8-K for November 27, 1996.

(8) Incorporated by reference to Form 10-KSB for the year ended June 30, 1996.

(9) Incorporated by reference to Form 8-K for May 29, 1996.

(10) Incorporated by reference to Form 8-K for March 27, 1997.

(11) Incorporated by reference to Form 10-K for the year ended June 30, 1997.

(12) Incorporated by reference to Form 8-K for January 14, 1998.

(13) Incorporated by reference to Form 8-K for February 16, 1998.


Item 17.    Undertakings

(a)  The undersigned Company hereby undertakes:

     (1) To file,  during any period in which  offers or sales are being made, a
     post-effective amendment to this registration statement:

            (i)       To include any prospectus required by Section (10)(a)(3)
                      of the Securities Act;

            (ii)       To reflect in the  prospectus any facts or events arising
                       after the effective date of this  Registration  Statement
                       (or the most  recent  post-effective  amendment  thereof)
                       which,  individually  or in the  aggregate,  represent  a
                       fundamental  change in the  information set forth in this
                       Registration Statement;

            (iii)      To include any material  information  with respect to the
                       plan of  distribution  not  previously  disclosed in this
                       Registration  Statement  or any  material  change to such
                       information in this Registration Statement.

     Provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii),  above, do not
     apply  if the  information  required  to be  included  in a  post-effective
     amendment by these paragraphs is contained in



<PAGE>ii-4



     periodic  reports  filed with or  furnished by the  Registrant  pursuant to
     Section 13 or 15(d) of the Exchange Act that are  incorporated by reference
     in this Registration Statement.

     (2)            That, for the purpose of determining any liability under the
     Securities Act, each such post-effective  amendment shall be deemed to be a
     new registration  statement relating to the securities offered therein, and
     the  offering  of such  securities  at that time  shall be deemed to be the
     initial bona fide offering thereof.

     (3)            To remove from  registration by means of a post-effective
     amendment any of the securities  being  registered which remain unsold at
    the termination of the offering.

(b)  The  undersigned   Registrant  hereby  undertakes  that,  for  purposes  of
     determining  liability  under  the  Securities  Act,  each  filing  of  the
     Registrant's  annual  report  pursuant to Section 13(a) or Section 15(d) of
     the Exchange  Act that is  incorporated  by reference in this  Registration
     Statement shall be deemed to be a new  registration  statement  relating to
     the securities  offered herein, and the offering of such securities at that
     time shall be deemed to be the initial bona fide offering thereof.

(c)  Insofar as indemnification for liabilities arising under the Securities Act
     of 1933 may be permitted to directors,  officers and controlling persons of
     THERMOGENESIS  CORP.  pursuant to the foregoing  provisions,  or otherwise,
     THERMOGENESIS  CORP. has been advised that in the opinion of the Commission
     such  indemnification  is against public policy as expressed in the Act and
     is, therefore, unenforceable. In the event that a claim for indemnification
     against such liabilities (other than the payment by the Company of expenses
     incurred  or paid by a  director,  officer  or  controlling  person  of the
     Company in the  successful  defense of any action,  suit or  proceeding) is
     asserted by such director, officer or controlling person in connection with
     the securities being registered, the Company will, unless in the opinion of
     its counsel the matter has been settled by controlling precedent, submit to
     a  court  of   appropriate   jurisdiction   the   question   whether   such
     indemnification  by it  is  against  public  policy  as  expressed  in  the
     Securities  Act and will be  governed  by the  final  adjudication  of such
     issue.


<PAGE>ii-5



                                   SIGNATURES

Pursuant  to  the  requirements  of the  Securities  Act of  1933,  the  Company
certifies  that it has  reasonable  grounds to believe  that it meets all of the
requirements  for  filing  on Form S-3 and has  duly  caused  this  registration
statement  to be  signed  on its  behalf  by  the  undersigned,  thereunto  duly
authorized,  in Rancho Cordova,  County of Sacramento,  State of California,  on
February 8, 1999.

                                         THERMOGENESIS CORP.

                                         /s/ PHILIP H. COELHO
                                         --------------------------------------
                                             Philip H. Coelho, Chairman & C.E.O.

KNOW ALL PERSONS BY THESE  PRESENTS,  that each person whose  signature  appears
below constitutes and appoints James H. Godsey or David C. Adams as his true and
lawful   attorney-in-fact  and  agent,  with  full  power  of  substitution  and
re-substitution,  for him and in his  name,  place,  and  stead,  in any and all
capacities, to sign any and all amendments (including post-effective amendments)
to this registration statement, and to file the same, with all exhibits thereto,
and other  documents in connection  therewith,  with the Securities and Exchange
Commission,  granting  unto said  attorneys-in-fact  and  agent,  full power and
authority to do and perform each and every act and thing requisite and necessary
to be done in connection  therewith,  as fully to all intents and purposes as he
might or could do in  person,  hereby  ratifying  and  confirming  all that said
attorney-in-fact  and agent or any of them, or of his substitute or substitutes,
may lawfully do or cause to be done by virtue hereof.

Pursuant to the  requirements of the Securities Act of 1933,  this  registration
statement has been signed below by the following  persons in the  capacities and
on the dates indicated:


 /s/PHILIP H. COELHO                                   Dated: February 8,1999
- ------------------------------                                
Philip H. Coelho, C.E.O.
and Chairman of the Board
(Principal Executive Officer)

 /s/ RENEE M. RUECKER                                   Dated: February 8,1999
- ----------------------------------------
Renee M. Ruecker, Vice President Finance
(Principal Accounting Officer and
Principal Financial Officer)

 /s/ JAMES H. GODSEY                                    Dated: February 8,1999
- --------------------------------------------
James H. Godsey, President, C.O.O. Director

                                                        Dated:
Hubert E. Huckel, Director

 /s/ PATRICK MCENANY                                    Dated: February 8,1999
- ---------------------------
Patrick McEnany, Director




                                                   EXHIBIT 5.1.

February 8, 1999


Board of Directors
THERMOGENESIS CORP.
3146 Gold Camp Drive
Rancho Cordova, California 95670

RE:  Common Stock of THERMOGENESIS CORP.

Dear Gentlemen:

I have acted as general counsel to THERMOGENESIS  CORP., a Delaware  corporation
(the "Company"),  in connection with the registration of 5,677,700 shares of the
Company's  common stock (the  "Shares")  under the  Securities  Act of 1933,  as
amended (the  "Securities  Act"), of which 290,000 of the Shares will be offered
to holders of the Company's  warrants,  and all of which will be sold by selling
stockholders of the Company as further  described in the Company's  registration
statement  on Form  S-3  filed  under  the  Securities  Act  (the  "Registration
Statement").

For the purpose of rendering  this  opinion,  I examined  originals or copies of
such  documents  as deemed to be  relevant.  In  conducting  my  examination,  I
assumed,  without  investigation,   the  genuineness  of  all  signatures,   the
correctness of all certificates,  the authenticity of all documents submitted to
me as originals, the conformity to original documents of all documents submitted
as certified or photostatic  copies,  and the  authenticity  of the originals of
such copies,  and the accuracy and completeness of all records made available to
me by the Company.  In addition,  in rendering this opinion,  I assumed that the
Shares will be offered in the manner and on the terms  identified or referred to
in the Registration Statement, including all amendments thereto.

My opinion is limited  solely to matters  set forth  herein.  I am  admitted  to
practice  in the State of  California  and I express no opinion as to the law of
any other jurisdiction other than the laws of the State of Delaware and the laws
of the United States.

Based upon and subject to the foregoing,  after giving due regard to such issues
of law as I deemed relevant,  and assuming that (i) the  Registration  Statement
becomes  and  remains  effective,  and  the  Prospectus  which  is a part of the
Registration   Statement  (the   "Prospectus"),   and  the  Prospectus  delivery
requirements  with  respect  thereto,  fulfill  all of the  requirements  of the
Securities Act, throughout all periods relevant to the opinion,  (ii) all offers
and sales of the Shares will be made in compliance  with the securities  laws of
the states having jurisdiction  thereof, and (iii) the Company receives,  to the
extent applicable, the consideration set forth in


<PAGE>



the  Prospectus,  I am of the opinion that the Shares issued are, and the Shares
to be issued will be, legally issued, fully paid and nonassessable.

I hereby  consent  in  writing  to the use of my  opinion  as an  exhibit to the
Registration  Statement and any amendment thereto.  By giving such consent, I do
not thereby  admit that I come within the category of persons  where  consent is
required under Section 7 of the  Securities Act or the rules and  regulations of
the Securities and Exchange Commission.

Sincerely,


David C. Adams
General Counsel





                                               EXHIBIT 23.2



                             CONSENT OF ERNST & YOUNG LLP INDEPENDENT AUDITORS


We  consent to the  reference  to our firm under the  caption  "Experts"  in the
Registration  Statement (Form S-3) and related Prospectus of THERMOGENESIS CORP.
for  the  registration  of  5,677,700  shares  of its  common  stock  and to the
incorporation  by reference  therein of our report  dated August 17, 1998,  with
respect to the financial statements and schedule of THERMOGENESIS CORP. included
in its Annual  Report (Form 10-K) for the year ended June 30,  1998,  filed with
the Securities and Exchange Commission.

Sacramento, California
February 5, 1999




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