SEQUUS PHARMACEUTICALS INC
SC 13D/A, 1999-03-22
PHARMACEUTICAL PREPARATIONS
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<PAGE>
                       SECURITIES AND EXCHANGE COMMISSION
                              Washington, DC 20549

                                  SCHEDULE 13D
                                 (Rule 13d-101)

             INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT
            TO RULE 13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO
                                  RULE 13d-2(a)

                               (Amendment No. 4)1


                          SEQUUS Pharmaceuticals, Inc.
                                (Name of Issuer)

                         Common Stock, par value $0.0001
                         (Title of Class of Securities)

                                    817471105
                                 (CUSIP Number)

                                Thomas F. Steyer
                       Farallon Capital Management, L.L.C.
                         One Maritime Plaza, Suite 1325
                         San Francisco, California 94111
                                 (415) 421-2132
                  (Name, Address and Telephone Number of Person
                Authorized to Receive Notices and Communications)

                                 March 16, 1999
             (Date of Event which Requires Filing of this Statement)

      If the filing person has  previously  filed a statement on Schedule 13G to
report the  acquisition  that is the subject of this Schedule 13D, and is filing
this  schedule  because  of Rule  13d-1(e),  13d-1(f)  or  13d-1(g),  check  the
following box [ ].

               Note.  Schedules  filed in paper  format  shall  include a signed
      original and five copies of the schedule, including all exhibits. See Rule
      13d-7(b) for other parties to whom copies are to be sent.


                         (Continued on following pages)

                               Page 1 of 38 Pages

- --------
1    The  remainder  of this  cover  page  shall be filled  out for a  reporting
     person's  initial  filing on this form with respect to the subject class of
     securities,  and for any subsequent amendment containing  information which
     would alter disclosures provided in a prior cover page.


          The information required on the remainder of this cover page shall not
     be deemed to be "filed"  for the  purpose  of Section 18 of the  Securities
     Exchange  Act of 1934  or  otherwise  subject  to the  liabilities  of that
     section of the Act but shall be subject to all other  provisions of the Act
     (however, see the Notes).

<PAGE>

                                       13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Farallon Capital Partners, L.P.
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         California
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         PN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                               Page 2 of 38 Pages
<PAGE>

                                       13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Farallon Capital Institutional Partners, L.P.
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         California
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         PN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                               Page 3 of 38 Pages
<PAGE>

                                       13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Farallon Capital Institutional Partners II, L.P.
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         California
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         PN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                               Page 4 of 38 Pages
<PAGE>

                                       13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Farallon Capital Institutional Partners III, L.P.
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         Delaware
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         PN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                               Page 5 of 38 Pages
<PAGE>

                                       13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Tinicum Partners, L.P.
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         New York
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         PN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                               Page 6 of 38 Pages
<PAGE>

                                      13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Farallon Capital (CP) Investors, L.P.
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         Cayman Islands
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         PN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                               Page 7 of 38 Pages
<PAGE>

                                       13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Farallon Capital Management, L.L.C.
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         Delaware
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         IA, OO
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                               Page 8 of 38 Pages
<PAGE>

                                       13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Farallon Partners, L.L.C.
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         Delaware
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         OO
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 9 of 38 Pages
<PAGE>

                                       13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Enrique H. Boilini
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         Argentina
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 10 of 38 Pages
<PAGE>

                                       13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         David I. Cohen
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         South Africa
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 11 of 38 Pages
<PAGE>

                                       13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Joseph F. Downes
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 12 of 38 Pages
<PAGE>

                                       13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         William F. Duhamel
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 13 of 38 Pages
<PAGE>

                                       13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Fleur E. Fairman
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 14 of 38 Pages
<PAGE>

                                       13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Jason M. Fish
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 15 of 38 Pages
<PAGE>

                                       13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Andrew B. Fremder
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 16 of 38 Pages
<PAGE>

                                       13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Richard B. Fried
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 17 of 38 Pages
<PAGE>

                                       13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         William F. Mellin
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 18 of 38 Pages
<PAGE>

                                       13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Stephen L. Millham
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 19 of 38 Pages
<PAGE>

                                       13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Meridee A. Moore
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 20 of 38 Pages
<PAGE>


22
                                            13D
===============================
CUSIP No. 817471105
===============================

- ---------======================================================================
   1     NAMES OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

         Thomas F. Steyer
- ---------======================================================================
   2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                     (a) [   ]

                                                                     (b) [ X ]
- ---------======================================================================
   3     SEC USE ONLY

- ---------======================================================================
   4     SOURCE OF FUNDS*

         N/A
- ---------======================================================================
   5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT
         TO ITEM 2(d) OR 2(e)
                                                                        [    ]

- ---------======================================================================
   6     CITIZENSHIP OR PLACE OF ORGANIZATION

         United States
- ----------------------=========================================================
   NUMBER OF      7   SOLE VOTING POWER

    SHARES            -0-
                ------=========================================================
 BENEFICIALLY     8   SHARED VOTING POWER
   OWNED BY
                      -0-
                ------=========================================================
     EACH         9   SOLE DISPOSITIVE POWER

   REPORTING          -0-
                ------=========================================================
  PERSON WITH    10   SHARED DISPOSITIVE POWER

                      -0-
- ----------------------=========================================================
   11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         -0-
- ---------======================================================================
   12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
         CERTAIN SHARES*                                             [     ]

- ---------======================================================================
   13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

         0.0 %
- ---------======================================================================
   14    TYPE OF REPORTING PERSON*

         IN
- ---------======================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!

                              Page 21 of 38 Pages
<PAGE>

     This  Amendment  No. 4 to Schedule 13D amends the  Schedule  13D  initially
filed on  November  5, 1998  (collectively,  with all  amendments  thereto,  the
"Schedule  13D").  The Schedule 13D is being filed to reflect the  conversion on
March  16,  1999,  of all of the  Reporting  Persons'  Shares  into the right to
receive,  for each Share, 0.4 shares of common stock, par value $0.01 per share,
of ALZA  Corporation  ("ALZA"),  pursuant to the  Agreement  and Plan of Merger,
dated as of October 4, 1998 by and among ALZA, Argyle  Acquisition Corp. and the
Company (the "Merger Agreement").  For further information  regarding the Merger
Agreement,  see the Proxy Statement filed by the Company with the Securities and
Exchange Commission on February 18, 1999.

Item 2. Identity and Background.

     Footnote 2 of Item 2 of the  Schedule  13D is amended  and  restated in its
entirety as follows:

            Of the Shares reported by FCMLLC on behalf of the Managed Accounts 0
      Shares (equal to 0% of the total Shares currently outstanding) are held by
      The Absolute  Return Fund of The Common  Fund,  a  non-profit  corporation
      whose  principal  address  is 450 Post Road  East,  Westport,  Connecticut
      06881.

Item 5.  Interest in Securities of the Issuer.

      Item 5 of the  Schedule  13D is amended and  restated  in its  entirety as
follows:

A.   Farallon Capital Partners, L.P.

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover page hereto for FCP is  incorporated  herein by  reference.
               The percentage  amount set forth in Row 13 of such cover page and
               of each other cover page filed  herewith as well as Footnote  Two
               hereto is calculated based upon the 32,627,715 Shares outstanding
               as of January 19,  1999,  as reported by the Company in its Proxy
               Statement  dated  as  of  February  18,  1999,   filed  with  the
               Securities and Exchange Commission on February 18, 1999.

     (c)  There were no purchases or sales of the Shares since the filing of the
          prior Schedule 13D. The transfer date and number of Shares transferred
          for each transaction  since the filing of the prior Schedule 13D which
          is not a  purchase  or sale is set  forth on  Schedule  A. All of such
          transfers were consummated pursuant to the Merger Agreement.

                              Page 22 of 38 Pages
<PAGE>

     (d)  FPLLC as General  Partner  has the power to direct the affairs of FCP,
          including the  disposition  of the proceeds of the sale of the Shares.
          Steyer is the senior  managing  member of FPLLC,  and Boilini,  Cohen,
          Downes,  Duhamel,  Fairman, Fish, Fremder,  Fried, Mellin, Millham and
          Moore are managing members of FPLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

B.   Farallon Capital Institutional Partners, L.P.

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover page hereto for FCIP is incorporated herein by reference.

     (c)  There were no purchases or sales of the Shares since the filing of the
          prior Schedule 13D. The transfer date and number of Shares transferred
          for each transaction  since the filing of the prior Schedule 13D which
          is not a  purchase  or sale is set  forth on  Schedule  B. All of such
          transfers were consummated pursuant to the Merger Agreement.

     (d)  FPLLC as General  Partner has the power to direct the affairs of FCIP,
          including the  disposition  of the proceeds of the sale of the Shares.
          Steyer is the  senior  managing  member of FPLLC and  Boilini,  Cohen,
          Downes,  Duhamel,  Fairman, Fish, Fremder,  Fried, Mellin, Millham and
          Moore are managing members of FPLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

C.      Farallon Capital Institutional Partners II, L.P.

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover  page  hereto  for  FCIP  II  is  incorporated   herein  by
               reference.

     (c)  There were no purchases or sales of the Shares since the filing of the
          prior Schedule 13D. The transfer date and number of Shares transferred
          for each transaction  since the filing of the prior Schedule 13D which
          is not a  purchase  or sale is set  forth on  Schedule  C. All of such
          transfers were consummated pursuant to the Merger Agreement.

     (d)  FPLLC as General  Partner  has the power to direct the affairs of FCIP
          II,  including  the  disposition  of the  proceeds  of the sale of the
          Shares.  Steyer is the senior  managing  member of FPLLC and  Boilini,
          Cohen, Downes, Duhamel, Fairman, Fish, Fremder, Fried, Mellin, Millham
          and Moore are managing members of FPLLC.

                              Page 23 of 38 Pages
<PAGE>

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

D.   Farallon Capital Institutional Partners III, L.P.

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover  page  hereto  for  FCIP  III  is  incorporated  herein  by
               reference.

     (c)  There were no purchases or sales of the Shares since the filing of the
          prior Schedule 13D. The transfer date and number of Shares transferred
          for each transaction  since the filing of the prior Schedule 13D which
          is not a  purchase  or sale is set  forth on  Schedule  D. All of such
          transfers were consummated pursuant to the Merger Agreement.

     (d)  FPLLC as General  Partner  has the power to direct the affairs of FCIP
          III,  including  the  disposition  of the  proceeds of the sale of the
          Shares.  Steyer is the senior  managing  member of FPLLC and  Boilini,
          Cohen, Downes, Duhamel, Fairman, Fish, Fremder, Fried, Mellin, Millham
          and Moore are managing members of FPLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

E.  Tinicum Partners, L.P.

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover  page  hereto  for  Tinicum  is   incorporated   herein  by
               reference.

     (c)  There were no purchases or sales of the Shares since the filing of the
          prior Schedule 13D. The transfer date and number of Shares transferred
          for each transaction  since the filing of the prior Schedule 13D which
          is not a  purchase  or sale is set  forth on  Schedule  E. All of such
          transfers were consummated pursuant to the Merger Agreement.

     (d)  FPLLC as  General  Partner  has the power to  direct  the  affairs  of
          Tinicum,  including the disposition of the proceeds of the sale of the
          Shares.  Steyer is the senior  managing  member of FPLLC and  Boilini,
          Cohen, Downes, Duhamel, Fairman, Fish, Fremder, Fried, Mellin, Millham
          and Moore are managing members of FPLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

F.   Farallon Capital (CP) Investors, L.P.

                              Page 24 of 38 Pages
<PAGE>

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover page hereto for FCCP is incorporated herein by reference.

     (c)  There were no purchases or sales of the Shares since the filing of the
          prior Schedule 13D. The transfer date and number of Shares transferred
          for each transaction  since the filing of the prior Schedule 13D which
          is not a  purchase  or sale is set  forth on  Schedule  F. All of such
          transfers were consummated pursuant to the Merger Agreement.

     (d)  FPLLC as General  Partner has the power to direct the affairs of FCCP,
          including the  disposition  of the proceeds of the sale of the Shares.
          Steyer is the  senior  managing  member of FPLLC and  Boilini,  Cohen,
          Downes,  Duhamel,  Fairman, Fish, Fremder,  Fried, Mellin, Millham and
          Moore are managing members of FPLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

G.   Farallon Capital Management, L.L.C.

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover page hereto for FCMLLC is incorporated herein by reference.

     (c)  There were no purchases or sales of the Shares since the filing of the
          prior Schedule 13D. The transfer date and number of Shares transferred
          for each transaction  since the filing of the prior Schedule 13D which
          is not a  purchase  or sale is set  forth on  Schedule  G. All of such
          transfers were consummated pursuant to the Merger Agreement.

     (d)  FCMLLC,  as an  investment  adviser,  has  the  power  to  direct  the
          disposition  of the  proceeds  of the sale of the  Shares  held by the
          Managed  Accounts.  Steyer is the senior managing member of FCMLLC and
          Boilini, Cohen, Downes, Duhamel, Fish, Fremder, Fried, Mellin, Millham
          and Moore are managing members of FCMLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

H.   Farallon Partners, L.L.C.

     (a), (b)  The  information set forth in rows 7, 8, 9, 10, 11, and 13 of the
               cover page hereto for FPLLC is incorporated herein by reference.

     (c)  None.

     (d)  FPLLC as General  Partner  has the power to direct the  affairs of the
          Partnerships, including the disposition of the proceeds of the sale of
          the Shares. 

                              Page 25 of 38 Pages
<PAGE>

          Steyer is the  senior  managing  member of FPLLC and  Boilini,  Cohen,
          Downes,  Duhamel,  Fairman, Fish, Fremder,  Fried, Mellin, Millham and
          Moore are managing members of FPLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

I.   Enrique H. Boilini

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover  page  hereto  for  Boilini  is   incorporated   herein  by
               reference.

     (c)  None.

     (d)  FPLLC as General  Partner  has the power to direct the  affairs of the
          Partnerships, including the disposition of the proceeds of the sale of
          the Shares.  FCMLLC, as an investment adviser, has the power to direct
          the  disposition of the proceeds of the sale of the Shares held by the
          Managed Accounts. Boilini is a managing member of FCMLLC and FPLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

J.   David I. Cohen

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover page hereto for Cohen is incorporated herein by reference.

     (c)  None.

     (d)  FPLLC as General  Partner  has the power to direct the  affairs of the
          Partnerships, including the disposition of the proceeds of the sale of
          the Shares.  FCMLLC, as an investment adviser, has the power to direct
          the  disposition of the proceeds of the sale of the Shares held by the
          Managed Accounts. Cohen is a managing member of FCMLLC and FPLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

K.   Joseph F. Downes

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover page hereto for Downes is incorporated herein by reference.

     (c)  None.

                              Page 26 of 38 Pages
<PAGE>

     (d)  FPLLC as General  Partner  has the power to direct the  affairs of the
          Partnerships, including the disposition of the proceeds of the sale of
          the Shares.  FCMLLC, as an investment adviser, has the power to direct
          the  disposition of the proceeds of the sale of the Shares held by the
          Managed Accounts. Downes is a managing member of FCMLLC and FPLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

L.   William F. Duhamel

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover  page  hereto  for  Duhamel  is   incorporated   herein  by
               reference.

     (c)  None.

     (d)  FPLLC as General  Partner  has the power to direct the  affairs of the
          Partnerships, including the disposition of the proceeds of the sale of
          the Shares.  FCMLLC, as an investment adviser, has the power to direct
          the  disposition of the proceeds of the sale of the Shares held by the
          Managed Accounts. Duhamel is a managing member of FCMLLC and FPLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

M.   Fleur E. Fairman

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover  page  hereto  for  Fairman  is   incorporated   herein  by
               reference.

     (c)  None.

     (d)  FPLLC as General  Partner  has the power to direct the  affairs of the
          Partnerships, including the disposition of the proceeds of the sale of
          the Shares. Fairman is a managing member of FPLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

N.   Jason M. Fish

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover page hereto for Fish is incorporated herein by reference.

     (c)  None.

                              Page 27 of 38 Pages
<PAGE>

     (d)  FPLLC as General  Partner  has the power to direct the  affairs of the
          Partnerships, including the disposition of the proceeds of the sale of
          the Shares.  FCMLLC, as an investment adviser, has the power to direct
          the  disposition of the proceeds of the sale of the Shares held by the
          Managed Accounts. Fish is a managing member of FCMLLC and FPLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

O.   Andrew B. Fremder

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover  page  hereto  for  Fremder  is   incorporated   herein  by
               reference.

     (c)  None.

     (d)  FPLLC as General  Partner  has the power to direct the  affairs of the
          Partnerships, including the disposition of the proceeds of the sale of
          the Shares.  FCMLLC, as an investment adviser, has the power to direct
          the  disposition of the proceeds of the sale of the Shares held by the
          Managed Accounts. Fremder is a managing member of FCMLLC and FPLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

P.   Richard B. Fried

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover page hereto for Fried is incorporated herein by reference.

     (c)  None.

     (d)  FPLLC as General  Partner  has the power to direct the  affairs of the
          Partnerships, including the disposition of the proceeds of the sale of
          the Shares.  FCMLLC, as an investment adviser, has the power to direct
          the  disposition of the proceeds of the sale of the Shares held by the
          Managed Accounts. Fried is a managing member of FCMLLC and FPLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

Q.   William F. Mellin

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover page hereto for Mellin is incorporated herein by reference.

     (c)  None. 

                              Page 28 of 38 Pages
<PAGE>

     (d)  FPLLC as General  Partner  has the power to direct the  affairs of the
          Partnerships, including the disposition of the proceeds of the sale of
          the Shares.  FCMLLC, as an investment adviser, has the power to direct
          the  disposition of the proceeds of the sale of the Shares held by the
          Managed Accounts. Mellin is a managing member of FCMLLC and FPLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

R.   Stephen L. Millham

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover  page  hereto  for  Millham  is   incorporated   herein  by
               reference.

     (c)  None.

     (d)  FPLLC as General  Partner  has the power to direct the  affairs of the
          Partnerships, including the disposition of the proceeds of the sale of
          the Shares.  FCMLLC, as an investment adviser, has the power to direct
          the  disposition of the proceeds of the sale of the Shares held by the
          Managed Accounts. Millham is a managing member of FCMLLC and FPLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

S.   Meridee A. Moore

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover page hereto for Moore is incorporated herein by reference.

     (c)  None.

     (d)  FPLLC as General  Partner  has the power to direct the  affairs of the
          Partnerships, including the disposition of the proceeds of the sale of
          the Shares.  FCMLLC, as an investment adviser, has the power to direct
          the  disposition of the proceeds of the sale of the Shares held by the
          Managed Accounts. Moore is a managing member of FCMLLC and FPLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

T.   Thomas F. Steyer

     (a), (b)  The  information  set forth in Rows 7, 8, 9, 10, 11 and 13 of the
               cover page hereto for Steyer is incorporated herein by reference.

     (c)  None.

                              Page 29 of 38 Pages
<PAGE>

     (d)  FPLLC as General  Partner  has the power to direct the  affairs of the
          Partnerships, including the disposition of the proceeds of the sale of
          the Shares.  FCMLLC, as an investment adviser, has the power to direct
          the  disposition of the proceeds of the sale of the Shares held by the
          Managed  Accounts.  Steyer is the senior managing member of FCMLLC and
          FPLLC.

     (e)  As of March 16,  1999,  the  Reporting  Person  is not the  beneficial
          holder of any Shares.

     The Shares reported hereby for the  Partnerships  are owned directly by the
Partnerships  and those reported by FCMLLC on behalf of the Managed Accounts are
owned directly by the Managed Accounts. Each of Boilini, Cohen, Downes, Duhamel,
Fish,  Fremder,  Fried,  Mellin,  Millham,  Moore and Steyer may be deemed, as a
managing  member of FPLLC and  FCMLLC,  to be the  beneficial  owner of all such
Shares.  Each of FPLLC and Fairman, as a managing member of FPLLC, may be deemed
to be the beneficial owner of all such Shares owned by the Partnerships.  FCMLLC
may be deemed to be the beneficial owner of all such Shares owned by the Managed
Accounts. Each of FCMLLC, FPLLC, Boilini, Cohen, Downes, Duhamel, Fairman, Fish,
Fremder,   Fried,  Mellin,  Millham,  Moore  and  Steyer  hereby  disclaims  any
beneficial ownership of any such Shares.


                              Page 30 of 38 Pages
<PAGE>


                                   SIGNATURES


      After reasonable  inquiry and to the best of our knowledge and belief, the
undersigned  certify that the  information  set forth in this statement is true,
complete and correct.

Dated: March 22, 1999


                        /s/ Thomas F. Steyer
                        FARALLON  PARTNERS,  L.L.C.,  on its own  behalf  and as
                        General  Partner of  FARALLON  CAPITAL  PARTNERS,  L.P.,
                        FARALLON CAPITAL INSTITUTIONAL PARTNERS,  L.P., FARALLON
                        CAPITAL   INSTITUTIONAL   PARTNERS  II,  L.P.,  FARALLON
                        CAPITAL   INSTITUTIONAL   PARTNERS  III,  L.P.,  TINICUM
                        PARTNERS,  L.P.,  And FARALLON  CAPITAL (CP)  INVESTORS,
                        L.P.
                        By Thomas F. Steyer,
                        Senior Managing Member



                        /s/ Thomas F. Steyer
                        FARALLON CAPITAL MANAGEMENT, L.L.C.,
                        By Thomas F. Steyer,
                        Senior Managing Member



                        /s/ Thomas F. Steyer
                        Thomas F. Steyer, individually and as attorney-in-fact
                        for each of Enrique H. Boilini, David I. Cohen, Joseph 
                        F. Downes, William F. Duhamel, Fleur E. Fairman, 
                        Jason M. Fish, Andrew B. Fremder, Richard B. Fried, 
                        William F. Mellin, Stephen L. Millham, 
                        and Meridee A. Moore.

      The Powers of Attorney executed by Boilini,  Cohen, Downes, Fairman, Fish,
Fremder,  Mellin,  Millham  and Moore  authorizing  Steyer to sign and file this
Schedule 13D on each person's  behalf,  which were filed with Amendment No. 1 to
the Schedule 13D filed with the Securities and Exchange  Commission on September
26, 1997, by such  Reporting  Persons with respect to the Common Stock of Sphere
Drake Holdings  Limited,  are hereby  incorporated  by reference.  The Powers of
Attorney executed by Duhamel and Fried authorizing  Steyer to sign and file this
Schedule 13D on each person's  behalf,  which were filed with Amendment No. 1 to
the Schedule 13G filed with the  Securities  and Exchange  Commission on January
13, 1999, by such Reporting  Persons with respect to the Callable Class A Common
Shares of CliniChem Development Inc., are hereby incorporated by reference.

                              Page 31 of 38 Pages
<PAGE>


                                   SCHEDULE A

                         FARALLON CAPITAL PARTNERS, L.P.



                                 NO. OF SHARES             PRICE
       TRADE DATE               TRANSFERRED (T)          PER SHARE 
                                                  (including commission)

        03/16/99                 558,800 (T)               N/A2

- --------
2    Such  transfer  represents  the  conversion of each Share into the right to
     receive 0.4 shares of the common stock, par value $0.01 per share, of ALZA,
     pursuant to the Merger Agreement. 

                              Page 32 of 38 Pages
<PAGE>


                                   SCHEDULE B

                  FARALLON CAPITAL INSTITUTIONAL PARTNERS, L.P.


                                NO. OF SHARES               PRICE
       TRADE DATE              TRANSFERRED (T)            PER SHARE 
                                                   (including commission)

        03/16/99                 776,700 (T)                N/A3

- --------
3    Such  transfer  represents  the  conversion of each Share into the right to
     receive 0.4 shares of the common stock, par value $0.01 per share, of ALZA,
     pursuant to the Merger Agreement.

                              Page 33 of 38 Pages
<PAGE>


                                   SCHEDULE C

                      FARALLON CAPITAL INSTITUTIONAL PARTNERS II, L.P.

                                NO. OF SHARES               PRICE
       TRADE DATE              TRANSFERRED (T)            PER SHARE 
                                                   (including commission)

        03/16/99                 157,400 (T)                N/A4

- --------
4    Such  transfer  represents  the  conversion of each Share into the right to
     receive 0.4 shares of the common stock, par value $0.01 per share, of ALZA,
     pursuant to the Merger Agreement.

                              Page 34 of 38 Pages
<PAGE>


                                   SCHEDULE D

                FARALLON CAPITAL INSTITUTIONAL PARTNERS III, L.P.


                                NO. OF SHARES               PRICE
       TRADE DATE              TRANSFERRED (T)            PER SHARE 
                                                   (including commission)

        03/16/99                 167,000 (T)                N/A5

- --------
5    Such  transfer  represents  the  conversion of each Share into the right to
     receive 0.4 shares of the common stock, par value $0.01 per share, of ALZA,
     pursuant to the Merger Agreement.

                              Page 35 of 38 Pages
<PAGE>

                                   SCHEDULE E

                             TINICUM PARTNERS, L.P.


                                 NO. OF SHARES             PRICE
       TRADE DATE               TRANSFERRED (T)          PER SHARE 
                                                  (including commission)

        03/16/99                  60,300 (T)               N/A6

- --------
6    Such  transfer  represents  the  conversion of each Share into the right to
     receive 0.4 shares of the common stock, par value $0.01 per share, of ALZA,
     pursuant to the Merger Agreement.

                              Page 36 of 38 Pages
<PAGE>

                                   SCHEDULE F

                      FARALLON CAPITAL (CP) INVESTORS, L.P.


                                 NO. OF SHARES             PRICE
       TRADE DATE               TRANSFERRED (T)          PER SHARE 
                                                  (including commission)

        03/16/99                  29,600 (T)               N/A7

- --------
7    Such  transfer  represents  the  conversion of each Share into the right to
     receive 0.4 shares of the common stock, par value $0.01 per share, of ALZA,
     pursuant to the Merger Agreement.

                              Page 37 of 38 Pages
<PAGE>

                                   SCHEDULE G

                       FARALLON CAPITAL MANAGEMENT, L.L.C.

                                 NO. OF SHARES             PRICE
       TRADE DATE               TRANSFERRED (T)          PER SHARE 
                                                  (including commission)

        03/16/99                 1,183,870 (T)             N/A8

        03/16/99                  31,500 (T)               N/A8

        03/16/99                  153,530 (T)              N/A8

- --------
8    Such  transfer  represents  the  conversion of each Share into the right to
     receive 0.4 shares of the common stock, par value $0.01 per share, of ALZA,
     pursuant to the Merger Agreement.

                              Page 38 of 38 Pages


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