FIRST TRUST OF INSURED MUNICIPAL BONDS SERIES 159
485BPOS, 1996-08-01
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                                                File No. 33-13813


               SECURITIES AND EXCHANGE COMMISSION
                   WASHINGTON, D.C. 20549-1004
                                
                                
                         POST-EFFECTIVE
                         AMENDMENT NO. 9
                                
                                
                               TO
                                
                            FORM S-6

For Registration Under the Securities Act of 1933 of Securities
of Unit Investment Trusts Registered on Form N-8B-2


     THE FIRST TRUST OF INSURED MUNICIPAL BONDS, SERIES 159
                      (Exact Name of Trust)
                                
                                
                      NIKE SECURITIES L.P.
                    (Exact Name of Depositor)
                                
                                
                      1001 Warrenville Road
                     Lisle, Illinois  60532
                                
                                
  (Complete address of Depositor's principal executive offices)
                                


          NIKE SECURITIES L.P.     CHAPMAN AND CUTLER
          Attn:  James A. Bowen    Attn:  Eric F. Fess
          1001 Warrenville Road    111 West Monroe Street
          Lisle, Illinois  60532   Chicago, Illinois  60603


        (Name and complete address of agents for service)
                                
                                
                                
                                
              CONTENTS OF POST-EFFECTIVE AMENDMENT
                    OF REGISTRATION STATEMENT
     
     This  Post-Effective  Amendment  of  Registration  Statement
comprises the following papers and documents:

                          The facing sheet

                          The purpose of the Amendment

                          The signatures

                                
                  THE PURPOSE OF THE AMENDMENT
     
     The   purpose   of  this  amendment  is  to  terminate   the
declaration  made  pursuant to Rule 24f-2  promulgated  under  the
Investment Company Act of 1940, as amended, because Units of  The
First  Trust of Insured Municipal Bonds, Series 159 are no longer
being  offered for sale in the secondary market.   A  final  Rule
24f-2   Notice  with  respect  to  such  series  has  been   filed
concurrently with this filing.
                                
                           SIGNATURES
     
     Pursuant to the requirements of the Securities Act of  1933,
the  Registrant,  The  First Trust of  Insured  Municipal  Bonds,
Series  159, certifies that it meets all of the requirements  for
effectiveness  of  this Registration Statement pursuant  to  Rule
485(b) under the Securities Act of 1933 and has duly caused  this
Post-Effective  Amendment  of its Registration  Statement  to  be
signed on its behalf by the undersigned thereunto duly authorized
in the Village of Lisle and State of Illinois on August 1, 1996.
                                    
                         THE FIRST TRUST OF INSURED MUNICIPAL
                           BONDS, SERIES 159
                                                 (Registrant)
                         By      NIKE SECURITIES L.P.
                                                  (Depositor)
                         
                         
                         By      Robert M. Porcellino
                                 Vice President
                                    
     
     Pursuant to the requirements of the Securities Act of  1933,
this  Post-Effective Amendment of Registration Statement has been
signed  below by the following person in the capacity and on  the
date indicated:

Signature                  Title*                  Date

Robert D. Van Kampen  Sole Director of    )
                      Nike Securities     )
                     Corporation, the     )
                      General Partner     ) August 1, 1996
                  of Nike Securities L.P. )
                                          )
                                          )
                                          )Robert M. Porcellino
                                          )Attorney-in-Fact**


*The title of the person named herein represents his capacity  in
     and relationship to Nike Securities L.P., the Depositor.

**An executed copy of the related power of attorney was filed  wi
     th the Securities and Exchange Commission in connection with
     Amendment  No.  1  to Form S-6 of The First  Trust  Combined
     Series  258  (File  No. 33-63483) and  the  same  is  hereby
     incorporated herein by this reference.
                                



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