PAINEWEBBER R&D PARTNERS II LP
10-Q, 1996-05-14
COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH
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                               UNITED STATES
                    SECURITIES AND EXCHANGE COMMISSION
                          WASHINGTON, D.C.  20549
                            -------------------

                                 FORM 10-Q

  
              (X) QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(D) OF
                       THE SECURITIES EXCHANGE ACT OF 1934.
                   FOR THE QUARTERLY PERIOD ENDED MARCH 31, 1996
                                        OR
           ( ) TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE
                         SECURITIES EXCHANGE ACT OF 1934.
                  FOR THE TRANSITION PERIOD FROM ______ TO ______



                          Commission File Number 33-14582
                         PAINEWEBBER R&D PARTNERS II, L.P.
              (Exact name of registrant as specified in its charter)




           DELAWARE                                     13-3437420
(State or other jurisdiction of                      (I.R.S. Employer
incorporation or organization)                      Identification No.)


1285 AVENUE OF THE AMERICAS, NEW YORK, NEW YORK         10019
   (Address of principal executive offices)           (Zip code)

     Registrant's telephone number, including area code: (212) 713-2000

                            ---------------------


         Indicate by check mark whether the Registrant (1) has filed all 
reports required to be filed by Section 13 or 15(d) of the Securities Exchange
Act of 1934 during the preceding 12 months (or for such shorter period that 
the Registrant was required to file such reports), and (2) has been subject 
to such filing requirements for the past 90 days.  Yes   X    No


<PAGE>                         Page 1

                      PAINEWEBBER R&D PARTNERS II, L.P.
                      (a Delaware Limited Partnership)

                              FORM 10-Q
                            MARCH 31, 1996
                          TABLE OF CONTENTS

PART I.              FINANCIAL INFORMATION                       Page

Item 1.              Financial Statements

                     Statements of Financial Condition
                     (unaudited) at March 31, 1996 and December   2
                     31, 1995

                     Statements of Operations
                     (unaudited) for the three months ended
                     March 31, 1996 and 1995                      3

                     Statement of Changes in Partners' Capital
                     (unaudited) for the three months ended
                     March 31, 1996                               3

                     Statements of Cash Flows
                     (unaudited) for the three months ended
                     March 31, 1996 and 1995                      4

                     Notes to Financial Statements
                     (unaudited)                                 5-11

Item 2.              Management's Discussion and Analysis of      12
                     Financial Condition and Results of
                     Operations

PART II.             OTHER INFORMATION

Item 1.              Legal Proceedings                            13

Item 6.              Exhibits and Reports on Form 8-K             13

                     Signatures                                   14




All schedules are omitted either because they are not applicable or the 
information required to be submitted has been included in the financial 
statements or notes thereto.


<PAGE>                         Page 2

                      PART I. FINANCIAL INFORMATION
   
Item 1. Financial Statements

PAINEWEBBER R&D PARTNERS II, L.P.
(a Delaware Limited Partnership)

Statements of Financial Condition
(unaudited)
                                                        March 31,   December 31,
                                                             1996          1995
- -------------------------------------------------------------------------------
Assets:

   Cash                                              $     26,210  $      5,858

   Marketable securities, at market value               1,214,887     1,247,309

   Investments, at fair value                           3,292,500     3,791,626

   Interest receivable                                      3,861         5,518

   Investments in product development projects            166,275       189,256

   Royalty income receivable                               31,765        26,158
                                                     ------------  ------------

Total assets                                         $  4,735,498  $  5,265,725
                                                     ============  ============


Liabilities and partners' capital:

   Accrued liabilities                               $    101,455  $     97,486

   Partners' capital                                    4,634,043     5,168,239
                                                     ------------  ------------
Total liabilities and partners' capital              $  4,735,498  $  5,265,725
                                                     ============  ============

- -------------------------------------------------------------------------------
See notes to financial statements.
   
<PAGE>                         Page 3   

   
PAINEWEBBER R&D PARTNERS II, L.P.
(a Delaware Limited Partnership)

Statements of Operations
(unaudited)

For the three months ended March 31,                     1996          1995
- -------------------------------------------------------------------------------
Revenues:
   Interest income                                  $     11,993  $     28,323
   Income from product development project                31,765        27,731
   Unrealized (depreciation) appreciation of 
     investments and marketable securities              (453,101)    1,531,958

   Gain on sale of investment                              8,474             -
                                                        --------     ---------
                                                        (400,869)    1,588,012
                                                        --------     ---------

Expenses:
   Expenditures under product development
     projects                                              3,013         4,149
   Management fee                                         68,505       125,582
   General and administrative costs                       61,809        67,694
                                                        --------     ---------
                                                         133,327       197,425
                                                        --------     ---------

Net income (loss)                                  $    (534,196)  $ 1,390,587
                                                        ========     =========

Net income (loss) per partnership unit:
   Limited partners (based on 8,257 units)         $      (64.05)  $   166.73
   General partner                                 $   (5,341.96)  $13,905.87

- -------------------------------------------------------------------------------
See notes to financial statements.




Statement of Changes in Partners' Capital
(unaudited)
                                              Limited     General
For the three months ended March 31, 1996     Partners    Partner      Total
- -------------------------------------------------------------------------------
Balance at December 31, 1995              $  5,114,512  $  53,727  $ 5,168,239

Net loss                                      (528,854)    (5,342)    (534,196)
                                          ------------  ---------  -----------
Balance at March 31, 1996                 $  4,585,658  $  48,385  $ 4,634,043
                                          ============  =========  ===========
- -------------------------------------------------------------------------------
See notes to financial statements.
   

<PAGE>                         Page 4


PAINEWEBBER R&D PARTNERS II, L.P.
(a Delaware Limited Partnership)

Statements of Cash Flows
(unaudited)

For the three months ended March 31,                     1996          1995
- ------------------------------------------------------------------------------

Cash flows from operating activities:
Net income (loss)                                   $  (534,196)  $  1,390,587
Adjustments to reconcile net income (loss) to 
  cash provided by operating activities:
Unrealized depreciation (appreciation) of 
  investments and marketable securities                  453,101   (1,531,958)
Equity in earnings of product development projects         3,013        4,149

Decrease (increase) in operating assets:
  Marketable securities                                   78,448    1,028,650
  Interest receivable                                      1,657        3,429
  Royalty income receivable                               (5,607)      14,741

Increase in operating liabilities:
  Accrued liabilities                                      3,969        6,630
                                                      ----------   ----------
Cash provided by operating activities                        385      916,228
                                                      ----------   ----------

Cash flows from investing activities:
   Distributions from product development project         19,967            -
                                                      ----------   ----------
Cash flows from financing activities:
  Distributions to partners                                    -     (917,444)
                                                      ----------   ----------

Increase (decrease) in cash                               20,352       (1,216)

Cash at beginning of period                                5,858        6,703
                                                      ----------   ----------
Cash at end of period                               $     26,210  $     5,487
                                                      ==========  ===========


- ------------------------------------------------------------------------------
Supplemental disclosure of cash flow information:
The Partnership paid no cash for interest or taxes during the three months 
ended March 31, 1996 and 1995.

- ------------------------------------------------------------------------------
See notes to financial statements.
   
<PAGE>                         Page 5

                     PAINEWEBBER R&D PARTNERS II, L.P.
                     (a Delaware Limited Partnership)

                       NOTES TO FINANCIAL STATEMENTS
                                (UNAUDITED)



1. ORGANIZATION AND BUSINESS

   The financial information as of and for the periods ended March 31, 1996 
and 1995 is unaudited. However, in the opinion of management of PaineWebber 
R&D Partners II, L.P. (the "Partnership"), such information includes all
adjustments, consisting only of normal recurring accruals, necessary 
for a fair presentation.  The results of operations reported for 
the interim period ended March 31, 1996, are not necessarily 
indicative of results to be expected for the year ended December 31, 1996.
These financial statements should be read in conjunction with the most  
recent annual report of the Partnership on Form 10-K for the year ended 
December 31, 1995.

   The Partnership is a Delaware limited partnership that commenced
operations on September 30, 1987 with a total of $72.0 million available for
investment.  PWDC Holding Company (the "Manager") is the general partner of
PaineWebber Technologies II, L.P. (the "General Partner"), which is the
general partner of the Partnership. PWDC Holding Company is a wholly owned
subsidiary of PaineWebber Development  Corporation ("PWDC"), an indirect,
wholly owned subsidiary of Paine Webber Group Inc. The Partnership  will
terminate on December 31, 2012, unless its term is extended or reduced by the
General Partner.

   The principal objective of the Partnership is to provide long-term capital
appreciation to investors through investing in the development  and
commercialization of new products with technology companies ("Sponsor
Companies"), which are expected to address significant  market
opportunities.  Once the product development phase is completed, the Sponsor
Companies have the option to license and commercialize the products
resulting from the product development project, and the Partnership has the
right to receive payments based upon the sale of such products. In connection
with product development projects (the "Projects"), the Partnership sought to
obtain warrants to purchase the common stock of Sponsor Companies. These 
warrants will have the potential to provide additional capital appreciation to
the Partnership which is not directly dependent upon the outcome of the Projects
(see Note 5). In addition, the Partnership invests as a limited partner in
product development limited partnerships.  Such partnerships were formed to
develop specific, new products through contracts with Sponsor Companies.
The Sponsor Companies conduct the Projects and affiliates of the Sponsor
Companies serve as general partners of the partnerships. As a result
of restructuring some of the original Projects, the Partnership also obtained
restricted common stock in some of the Sponsor Companies.  As such, the
Partnership is engaged in diverse Projects through contracts, participation in
other partnerships and investments in securities of the Sponsor Companies.

   All distributions to the limited partners of the Partnership (the "Limited
Partners") and the General Partner (collectively, the "Partners") from the
Partnership will initially be made pro rata in accordance with their
respective net capital contributions.  The following table sets forth
the proportion of each distribution to be received by the Limited Partners and
the General Partner, respectively:


<PAGE>                         Page 6


                     PAINEWEBBER R&D PARTNERS II, L.P.
                     (a Delaware Limited Partnership)

                       NOTES TO FINANCIAL STATEMENTS
                                (UNAUDITED)


(NOTE 1 CONTINUED)
<TABLE>
<CAPTION>
                                                                     Limited Partner  General Partner
                                                                     ---------------  ---------------

<S>                                                                        <C>            <C> 
I.   Until the value of the aggregate distributions for each
     limited partnership unit ("Unit") equals $10,000 plus simple
     interest on such amount accrued at 7% per annum for each
     Unit sold at the Initial Closing (6% per annum for each
     subsequent Unit sold up to the 5,000th Unit and 5% per annum
     for each Unit sold thereafter) ("Contribution Payout")..........         99%            1%

II.  After Contribution Payout and until the value of the
     aggregate distributions for each Unit equals $50,000 ("Final                           
     Payout")........................................................         80%           20%

III. After Final Payout..............................................         75%           25%

</TABLE>

   For the quarter ended March 31, 1996, the Partnership made no cash or 
security distributions. At March 31, 1996, the Partnership has made cash
and security distributions since inception of $1,585 and $7,297 per Unit, 
respectively.

  2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

   The financial statements are prepared in conformity with generally accepted
accounting principles which require management to make estimates and 
assumptions that affect the amounts reported in the financial statements and
accompanying notes. Actual results could differ from those estimates.

   The Partnership accounted for its investments in restricted common stock 
(where the restriction period expired in one year or less) held as of or 
acquired after January 1, 1994, in accordance with the provisions of 
Statement of Financial Accounting Standards No. 115, "Accounting for Certain 
Investments in Debt and Equity Securities".

   Marketable  securities consist of a money market fund and common stock 
which are recorded at market value. Marketable securities are not considered
cash equivalents for the Statements of Cash Flows.

   Realized and unrealized gains or losses are determined on a specific 
identification method and are reflected in the Statements of Operations 
during the period in which the change in value occurs.

   The Partnership invested in Projects, further described in Note 5, 
through one of the following two vehicles:


<PAGE>                         Page 7


                     PAINEWEBBER R&D PARTNERS II, L.P.
                     (a Delaware Limited Partnership)

                       NOTES TO FINANCIAL STATEMENTS
                                (UNAUDITED)




(NOTE 2 CONTINUED)

 -  Product  Development Contracts
    The  Partnership  paid  amounts  to  Sponsor  Companies  under  product
    development  contracts.   Such amounts were expensed by the Partnership
    when  incurred  by the Sponsor  Companies.   Income  from  the  Sponsor
    Companies is reflected  in  the Statements of Operations for the period
    in which the income is earned.
 
 -  Product Development Limited Partnerships
    The  Partnership  participates   as   a   limited  partner  in  product
    development limited partnerships formed to  develop  specific products.
    Such  participations are accounted for using the equity  method.   Such
    partnerships expensed product development costs when incurred.

   The Partnership carries warrants at a zero value in cases where the Sponsor
Company's stock is not publicly traded or the  exercise period has not been
attained.  To the extent that the Partnership's warrants are currently
exercisable and the Sponsor Company's stock is publicly traded, the warrants
are carried at intrinsic value (the excess of market price per share over the
exercise price per share), which approximates fair value.

   Certain reclassifications have been made in prior year amounts to conform to
current year presentations.

3. MARKETABLE SECURITIES AND INVESTMENTS

   MARKETABLE SECURITIES:

   The money market fund consists of obligations with maturities of one year or
less that are subject to fluctuations in value.


   The Partnership held the following marketable securities:

<TABLE>
<CAPTION>
                                                     MARCH 31, 1996                      DECEMBER 31, 1995
                                              ------------------------------      ------------------------------
                                                   MARKET            COST           MARKET             COST
                                              --------------     -----------      ------------     -------------
<S>                                          <C>                 <C>             <C>                 <C>
Money market fund                              $866,011            $866,011        $956,168            $956,168
Alkermes, Inc. common stock (3,227 shares)            -                   -          25,616              22,589
Cygnus, Inc. common stock (11,867 shares)       247,726              69,719         265,525              69,719
Centocor, Inc. common stock (2,800 shares)      101,150              37,324               -                   -
                                                -------             -------         -------             -------
                                             $1,214,887            $973,054      $1,247,309          $1,048,476
                                             ==========            ========      ==========           =========

</TABLE>


<PAGE>                         Page 8


                     PAINEWEBBER R&D PARTNERS II, L.P.
                     (a Delaware Limited Partnership)

                       NOTES TO FINANCIAL STATEMENTS
                                (UNAUDITED)



(NOTE 3 CONTINUED)

   In January 1996, the Partnership sold its investment of 3,227 common
shares of Alkermes, Inc. for proceeds, net of commissions, of $34,090 and
recognized a gain upon the sale for the quarter ended March 31, 1996 of
$8,474.  In February 1996, the Partnership exercised its warrants to
purchase 2,800 common shares of Centocor, Inc. ("Centocor") at an exercise
price of $13.33 per share. At March 31, 1996, Centocor common stock had a
market value of $36.125 per share.  Cygnus, Inc. ("Cygnus") common stock
had a market value as of March 31, 1996 and December 31, 1995, of $20.875
and $22.375 per share, respectively.

    INVESTMENTS:

The Partnership held the following investments:

<TABLE>
<CAPTION>


                                                  MARCH  31, 1996      DECEMBER  31, 1995
                                                  ---------------      ------------------
<S>                                                <C>                      <C> 
Cygnus, Inc.                                         $3,292,500               $3,742,500
   Warrants to purchase 300,000 common shares
Centocor, Inc.                                                -                   49,126
   Warrants to purchase 2,800 common shares          ----------               ----------
                                                     $3,392,500               $3,791,626
                                                     ==========               ==========
</TABLE>

   The Partnership recorded its warrants to purchase 300,000 common shares of
Cygnus as an investment with a carrying value equal to its intrinsic value
(which approximates fair value) -- (See Note 5).  The intrinsic value as of
March 31, 1996, and December 31, 1995, was $10.975 and $12.475 per share,
respectively.  Accordingly, the Partnership recognized unrealized depreciation
of $450,000 for the three months ended March 31, 1996, which has been included
in the accompanying Statements of Operations.  At December 31, 1995, the
Partnership recorded its investment in Centocor warrants at their intrinsic
value of $17.545 per share.  In February 1996, the Partnership exercised its
warrants for Centocor common shares (see Marketable Securities).



<PAGE>                         Page 9


                     PAINEWEBBER R&D PARTNERS II, L.P.
                     (a Delaware Limited Partnership)

                       NOTES TO FINANCIAL STATEMENTS
                                (UNAUDITED)



4. RELATED PARTY TRANSACTIONS

   The Manager receives an annual management fee for management and 
administrative services provided to the Partnership. The management fee is 
payable quarterly in advance and is adjusted  annually on the first day of 
each fiscal year in an amount proportionate to the increase in the prior 
year in the Consumer Price Index published by the United States Department of 
Labor.  The management fees paid by the Partnership to the Manager were $68,505
and $125,582 for the three months ended March 31, 1996 and 1995, respectively.
Aggregate management fees paid to the Manager since January 1, 1995, were 
$415,575.

   The Partnership's portfolio which consists of a money market fund is
managed by Mitchell Hutchins Institutional Investors ("MHII"), an affiliate of
PWDC.  PWDC pays MHII a fee with respect to such money management services.

   PWDC and Painewebber Incorporated, and its affiliates, have acted in an
investment banking capacity for several of the Sponsor Companies.  In addition,
PWDC and its affiliates  have direct limited partnership interests in the same
Projects as the Partnership.

5.  PRODUCT DEVELOPMENT PROJECTS

  The Partnership entered into nine Projects (Cadre Technologies Inc.; Centocor
Partners III, L.P.; Compression Labs, Incorporated; Cygnus; FOCUS Surgery Inc.
(formerly Focal Surgery, Inc. (successor to Diasonics, Inc.)); Genentech
Clinical Partners IV, L.P.; Genzyme  Development Partners, L.P.; Rogers
Corporation; and Synergen Clinical Partners, L.P) which have been fully funded.
In addition, the Partnership purchased $5.9 million of common stock of
Alkermes, Inc. which was distributed to its Partners in 1993 and 1994.

   On January 31, 1996, Genzyme Corporation ("Genzyme") made an offer (the
"Offer") to the general partner of Genzyme Development Partners, L.P. ("GDP")
(of which the Partnership owns a limited partnership interest) to acquire the
assets of GDP in exchange for common shares of Genzyme (the "Acquisition"). The
Offer was made in lieu of Genzyme's existing option to purchase the outstanding
partnership interests in GDP for a lump-sum cash payment and certain future
royalty payments.  The Offer is conditioned upon the approval of the general
partner of GDP, affirmation by a vote of a two-thirds interest of the limited
partners of GDP and certain assurances regarding the accounting treatment of
the Acquisition for Genzyme.  If the Acquisition is approved, the common shares
of Genzyme will be distributed to the limited partners of GDP (including the
Partnership).  (See Note 8 - Subsequent Event).

   In March 1996, FOCUS Surgery, Inc. ("FOCUS") announced the signing of a
letter of intent to Takai Hospital Supply Co. for the sale of all of the assets
of FOCUS.  Simultaneously, FOCUS filed for protection under Chapter 11 of the
U.S. Bankruptcy Code. The Partnership will continue to maintain its rights to
the technology under the project agreement with FOCUS but does not anticipate
realizing any further revenues therefrom.


<PAGE>                         Page 10

                     PAINEWEBBER R&D PARTNERS II, L.P.
                     (a Delaware Limited Partnership)

                       NOTES TO FINANCIAL STATEMENTS
                                (UNAUDITED)




(NOTE 5 CONTINUED)

   If the Projects produce any product for commercial sale, the Sponsor 
Companies have the option to enter into joint ventures or royalty agreements 
with the Partnership to manufacture and market the products developed.  In 
addition, the Sponsor Companies have the option to purchase the Partnership's 
interest in the technology.  In consideration for such purchase options, the 
Partnership has received warrants to purchase shares of common stock of the 
Sponsor Companies.  At March 31, 1996, the market price per share of Cygnus 
common stock exceeded the exercise price per share of the warrant and, 
accordingly, the Partnership recorded this warrant as an investment with 
a carrying value equal to its intrinsic value which approximates fair value 
(see Note 3).  At March 31, 1996, the Partnership owned the following warrants:

<TABLE>
<CAPTION>
                                 Number of Shares        Exercise                                    3/31/96
                                  that can be             Price                Exercise             Market Price
                                   Purchased            per Share                Period              per Share*
                                 ----------------       ---------            -------------          -------------         
<S>                               <C>                  <C>                  <C>                  <C>

Cadre Technologies, Inc.          625,000                $    5.00          Current to 6/97                    (A)
Cygnus, Inc. (B)                  300,000                $    9.90          Current to 9/97           $     20.875
OEC Medical Systems, Inc. (C)     200,000                $   12.70          Current to 8/97           $     11.750
</TABLE>


* The share prices of these technology  companies are generally highly volatile
and the shares are often thinly traded.  The market prices  indicated as of 
March 31, 1996, may not be indicative of the ultimate values, if any, that may 
be realized by the Partnership.



(A) At March 31, 1996, the common stock of Cadre Technologies Inc. ("Cadre") 
    was not publicly traded. In December 1995, Cadre announced a merger 
    agreement with Bachman Information Systems, Inc. ("Bachman").  At the time 
    of the closing of the merger, the Cadre warrants will convert into Bachman 
    warrants at a conversion ratio of 0.31496 Bachman warrants per Cadre 
    warrant.

(B) The carrying value of this warrant at its intrinsic value has been included
    in Investments in the accompanying Statements of Financial Condition.

(C) In October 1993, Diasonics, Inc. completed a major corporate restructuring
    under which Diasonics, Inc. was divided into three separate publicly traded
    companies: Diasonics Ultrasound, Inc., FOCUS Surgery Inc. and OEC Medical
    Systems, Inc.  The Partnership's warrant is to purchase the stock of OEC
    Medical Systems, Inc.

6.  INCOME TAXES

       The Partnership is not subject to federal, state or local income taxes.
Accordingly, the individual Partners are required to report their distributive
shares of realized income and loss on their individual federal and state income
tax returns.

<PAGE>                         Page 11

                     PAINEWEBBER R&D PARTNERS II, L.P.
                     (a Delaware Limited Partnership)

                       NOTES TO FINANCIAL STATEMENTS
                                (UNAUDITED)


7.  LEGAL PROCEEDING

   On July 12, 1995, the Partnership commenced an action against Centocor and
Centocor Development Corporation III ("CDC III") in the Chancery Court of
Delaware arising from certain agreements entered into by Centocor and Eli Lilly
& Company ("Lilly") in July 1992.  The Partnership's complaint alleges, among
other things that: at least $25 million of the $100 million paid by Lilly
represents profits from the sale of ReoPro, a Centocor drug, that Centocor is
required to share with Centocor Partners III, L.P. ("CP III"); and because of
the Lilly transaction, Centocor is required to increase the percentage of its
profits from ReoPro that it pays to CP III.  Centocor, however, has taken the
position that only $500,000 of the $100 million must be shared with CP III and
that Centocor has no obligation to increase the percentage of its ReoPro
profits that it pays to CP III.  The Partnership is seeking to proceed on
behalf of itself and all other limited partners of CP III.  The complaint seeks
to require Centocor and CDC III to pay damages to CP III and to increase the
percentage of future ReoPro profits that Centocor must pay to CP III. There can
be no assurance that the Partnership's claim will be successful.


   PWDC has been advancing, and may continue to advance, the funds necessary to
pay the Partnership's legal fees and expenses relating to this litigation.  In
the event of a recovery on behalf of CP III, the court may award legal fees and
expenses to the Partnership's counsel, to be paid out of the recovery.  It is
anticipated that: the net proceeds of any recovery will be distributed to the
limited partners of CP III, including the Partnership, on a pro rata basis; the
Partnership  and/or its counsel will reimburse PWDC; and any remaining
Partnership proceeds will be distributed to the Partners of the Partnership on
a pro rata basis.


8. SUBSEQUENT EVENT

      On May 6, 1996, Genzyme withdrew its Offer to purchase the assets of GDP.




<PAGE>                         Page 12



ITEM 2.  MANAGEMENT'S DISCUSSION  AND ANALYSIS OF FINANCIAL CONDITION AND 
         RESULTS  OF OPERATIONS 

LIQUIDITY AND CAPITAL RESOURCES

   Partners' capital decreased from $5.1 million at December 31, 1995, to $4.6
million at March 31, 1996, resulting from the recognition of a net loss of $0.5
million for the three months ended March 31, 1996.

   The Partnership's working capital is invested in marketable securities and a
money market fund. Liquid assets at March 31, 1996 and December 31, 1995, were
$1.3 million.  The balance of liquid assets will be used for the payment of
management fees and administrative costs related to managing the Partnership's
investments.

RESULTS OF OPERATIONS

Three months ended March 31, 1996 compared to the three months ended 
March 31, 1995: 

   The Partnership recognized a net loss for the quarter ended March 31, 
1996, of $0.5 million compared to net income of $1.4 million for the same 
period in 1995.  The unfavorable variance of $1.9 million was due to a 
decrease in revenues of this amount.

     Revenues for the quarters ended March 31, 1996 and 1995 of $(0.4)
million and $1.6 million, respectively, consisted primarily of the recognition
of  unrealized appreciation (depreciation) of marketable securities  and
investments.   As of March 31, 1996, the Partnership wrote down its investment
in warrants to purchase 300,000 common shares of Cygnus by $0.45 million to
reflect a decrease in the market value of Cygnus common stock from $22.375 at
December 31, 1995, to $20.875 at March 31, 1996.  For the three months ended
March 31, 1995, the Partnership recognized unrealized appreciation of $1.5
million with respect to its investment of 1,529,941 common shares of Cygnus to
reflect an increase in the market value of Cygnus common stock from $6.75 per
share at December 31, 1994 to $7.75 per share at March 31, 1995.



<PAGE>                         Page 13



ITEM 1. LEGAL PROCEEDINGS.

        ACTION AGAINST CENTOCOR, INC. AND CENTOCOR DEVELOPMENT CORPORATION III
   Information regarding this action was disclosed on the Partnership's
Form 10-K for the year ended December 31, 1995.  In April 1996,
Centocor, Inc. amended its pleadings in the Partnership's action, as
well as a second action commenced by another limited partner of
Centocor Partners III, L.P. to, among other things, add third-party
claims against PaineWebber Incorporated.

ITEM 6.EXHIBITS AND REPORTS ON FORM 8-K
a) EXHIBITS:
   None

b) REPORTS ON FORM 8-K:
   None



<PAGE>                         Page 14


   Pursuant to the requirements of Section 13 or 15(d) of the Securities
Exchange Act of 1934, the Registrant has duly caused this report to be signed
on its behalf by the undersigned, thereunto duly authorized, on this 15th day
of May 1996.



PAINEWEBBER R&D PARTNERS II, L.P.


By:           PaineWebber Technologies II, L.P.
              (General Partner)


By:           PWDC Holding Company
              (General partner of the General Partner)



By:           Eugene M. Matalene, Jr. /s/
              ------------------------------
              Eugene M. Matalene, Jr.
              President and Principal Executive Officer



By:           Pierce R. Smith/s/
              ------------------------------
              Pierce R. Smith
              Principal Financial and Accounting Officer


*The  capacities  listed are with respect to PWDC Holding Company, the Manager,
 as well as the general partner of the General Partner of the Registrant.




<TABLE> <S> <C>

<ARTICLE> 5
<CIK> 0000814576
<NAME> PAINEWEBBER R&D PARTNERS II, L.P.
       
<S>                             <C>
<PERIOD-TYPE>                   3-MOS
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