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<TABLE> <S> <C>
<ARTICLE> 5
<CIK> 0000814576
<NAME> PAINEWEBBER R&D PARTNERS II, L.P.
<S> <C>
<PERIOD-TYPE> 6-MOS
<FISCAL-YEAR-END> DEC-31-2000
<PERIOD-END> JUN-30-2000
<CASH> 6,998
<SECURITIES> 10,002,649
<RECEIVABLES> 1,550,000
<ALLOWANCES> 0
<INVENTORY> 0
<CURRENT-ASSETS> 11,559,647
<PP&E> 0
<DEPRECIATION> 0
<TOTAL-ASSETS> 11,559,647
<CURRENT-LIABILITIES> 156,515
<BONDS> 0
0
0
<COMMON> 0
<OTHER-SE> 11,403,132
<TOTAL-LIABILITY-AND-EQUITY> 11,559,647
<SALES> 0
<TOTAL-REVENUES> 10,500,047
<CGS> 0
<TOTAL-COSTS> 0
<OTHER-EXPENSES> 290,934
<LOSS-PROVISION> 0
<INTEREST-EXPENSE> 0
<INCOME-PRETAX> 10,209,113
<INCOME-TAX> 0
<INCOME-CONTINUING> 0
<DISCONTINUED> 0
<EXTRAORDINARY> 0
<CHANGES> 0
<NET-INCOME> 10,209,113
<EPS-BASIC> 0
<EPS-DILUTED> 0
</TABLE>
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