CELGENE CORP /DE/
DEF 14A, 1996-07-11
INDUSTRIAL ORGANIC CHEMICALS
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<PAGE>
<PAGE>
                           SCHEDULE 14A INFORMATION 

             Proxy Statement Pursuant to Section 14(a) of the Securities
                       Exchange Act of 1934 (Amendment No.    )

          Filed by the Registrant [X]
          Filed by a Party other than the Registrant [ ]


          Check the appropriate box:

          [ ]  Preliminary Proxy Statement
          [ ]  Confidential, for Use of the Commission Only (as permitted by
               Rule 14a-6(e)(2))
          [X]  Definitive Proxy Statement
          [ ]  Definitive Additional Materials
          [ ]  Soliciting Material Pursuant to Section 240.14a-11(c) or
               Section 240.14a-12

                                  CELGENE CORPORATION
          .................................................................
                   (Name of Registrant as Specified In Its Charter)

          .................................................................
       (Name of Person(s) Filing Proxy Statement, if other than the Registrant)


          Payment of Filing Fee (Check the appropriate box):

          [X]  $125 per Exchange Act Rules 0-11(c)(1)(ii), 14a-6(i)(1),
               14a-6(i)(2) or Item 22(a)(2) of Schedule 14A.
          [ ]  $500 per each party to the controversy pursuant to Exchange
               Act Rule 14a-6(i)(3).
          [ ]  Fee computed on table below per Exchange Act Rules 
               14a-6(i)(4) and 0-11.

               1)  Title of each class of securities to which transaction
          applies:
                    
          .................................................................

               2)  Aggregate number of securities to which transaction
          applies:
                    
          .................................................................

               3)  Per unit price or other underlying value of transaction
          computed   pursuant to Exchange Act Rule 0-11 (Set forth the
          amount on which the filing fee is calculated and state how it was
          determined):
                     
          .................................................................

               4)  Proposed maximum aggregate value of transaction:
                    
          .................................................................

               5)  Total fee paid:
                  
          .................................................................

          [ ]  Fee paid previously with preliminary materials.
          [ ]  Check box if any part of the fee is offset as provided by
               Exchange Act Rule 0-11(a)(2) and identify the filing for
               which the offsetting fee was paid previously.  Identify the
               previous filing by registration statement number, or the
               Form or Schedule and the date of its filing.

               1)   Amount Previously Paid:
                     
          .................................................................

               2)   Form, Schedule or Registration Statement No.:

          .................................................................

               3)   Filing Party:

          .................................................................

               4)   Date Filed:

          .................................................................

<PAGE>
<PAGE>
                              CELGENE CORPORATION
                              7 POWDER HORN DRIVE
                            WARREN, NEW JERSEY 07059
 
                            ------------------------
                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
 
                            ------------------------
 
     The   annual   meeting  of   stockholders   of  CELGENE   CORPORATION  (the
'Corporation') will be held at the offices of Proskauer Rose Goetz &  Mendelsohn
LLP,  1585 Broadway, 26th  floor, New York,  New York 10036  on Friday, June 14,
1996, at 1:00 p.m., local time, for the following purposes:
 
          1. to elect seven directors;
 
          2. to consider and act upon a proposal to approve the amendment of the
     Corporation's 1992 Long-Term Incentive Plan to continue to qualify it under
     Section 162(m)  of the  Internal  Revenue Code  of  1986, as  amended,  and
     regulations thereunder;
 
          3.  to consider and act upon a  proposal to confirm the appointment of
     KPMG Peat Marwick LLP  as the independent  certified public accountants  of
     the Corporation for the current fiscal year; and
 
          4. to transact any such other business as may properly come before the
     meeting and at any adjournment thereof.
 
     The Board of Directors has fixed the close of business on Friday, April 26,
1996  as the record date for determining  stockholders entitled to notice of and
to vote at the meeting.
 
     A proxy and return envelope are enclosed for your convenience.
 
                                          By order of the Board of Directors
                                          JOHN W. JACKSON
                                          Chairman of the Board and
                                          Chief Executive Officer
 
May 13, 1996
 
                             YOUR VOTE IS IMPORTANT
                        Please mark, sign, and date the
                                    enclosed
                       proxy card and return it promptly
                        in the enclosed self-addressed,
                               stamped envelope.
<PAGE>
<PAGE>
                              CELGENE CORPORATION
                              7 POWDER HORN DRIVE
                            WARREN, NEW JERSEY 07059
 
                       ---------------------------------
                                PROXY STATEMENT
                       ---------------------------------
 
     This   Proxy  Statement  is  furnished   to  the  stockholders  of  Celgene
Corporation, a Delaware corporation (the 'Corporation'), in connection with  the
solicitation  of proxies by the Board of Directors for use at the annual meeting
of stockholders of  the Corporation  to be  held on June  14, 1996,  and at  any
adjournment  thereof. A  copy of  the notice  of meeting  accompanies this Proxy
Statement. It  is anticipated  that the  mailing of  this Proxy  Statement  will
commence on or about May 14, 1996.
 
     Only stockholders of record at the close of business on April 26, 1996, the
record  date for the meeting, will  be entitled to notice of  and to vote at the
meeting. On the record date the Corporation had outstanding 9,111,133 shares  of
common  stock, par value $.01 per share (the 'Common Stock'), which are the only
securities of the Corporation entitled to vote at the stockholders meeting, each
share being entitled to one vote.
 
     Stockholders who execute proxies may  revoke them by giving written  notice
to  the  Chief Executive  Officer of  the  Corporation at  any time  before such
proxies are  voted. Attendance  at the  meeting  shall not  have the  effect  of
revoking  a  proxy unless  the stockholder  so attending  shall, in  writing, so
notify the Secretary  of the  meeting at  any time prior  to the  voting of  the
proxy.
 
     The  Board of Directors does not know of  any matter that is expected to be
presented  for  consideration  at  the  meeting,  other  than  the  election  of
directors,  amendment of the 1992 Long-Term  Incentive Plan and the confirmation
of the  appointment  of the  independent  certified public  accountants  of  the
Corporation for the current year. However, if other matters properly come before
the  meeting, the persons named in the accompanying proxy intend to vote thereon
in accordance with their judgment.
 
     The Corporation  will  bear  the  cost  of the  meeting  and  the  cost  of
soliciting  proxies,  including  the  cost of  mailing  the  proxy  material. In
addition to solicitation by mail, directors, officers, and regular employees  of
the Corporation (who will not be specifically compensated for such services) may
solicit  proxies  by  telephone or  otherwise.  Arrangements will  be  made with
brokerage houses  and other  custodians, nominees,  and fiduciaries  to  forward
proxies  and  proxy  material  to their  principals,  and  the  Corporation will
reimburse them for their expenses.
 
     All proxies received pursuant to this solicitation will be voted except  as
to  matters where authority to vote is specifically withheld and, where a choice
is specified as  to the proposal,  they will  be voted in  accordance with  such
specification.  If no  instructions are  given, the  persons named  in the proxy
solicited by the Board of  Directors of the Corporation  intend to vote FOR  the
nominees  for election  as directors of  the Corporation listed  herein, FOR the
approval of the amendment  of the Corporation's  1992 Long-Term Incentive  Plan,
and  FOR  the  confirmation of  the  appointment  of KPMG  Peat  Marwick  LLP as
independent certified  public accountants  of the  Corporation for  the  current
fiscal  year.  With regard  to  the election  of  directors, votes  cast  may be
withheld from each nominee;  votes that are withheld  will be excluded  entirely
from  the vote  and will  have no  effect. Abstentions  may be  specified on all
proposals except the election of directors,  and will be counted as present  for
purposes  of determining the existence  of a quorum regarding  the item on which
the abstention is noted.
 
<PAGE>
<PAGE>
     Pursuant to the  NASD Rules of  Fair Practice, brokers  who hold shares  in
street  name have  the authority, in  limited circumstances, to  vote on certain
items when they have not received instructions from beneficial owners. A  broker
will  only have such authority  if (i) the broker  holds the shares as executor,
administrator, guardian,  trustee, or  in  similar representative  or  fiduciary
capacity  with authority to  vote or (ii)  the broker is  acting pursuant to the
rules of any national securities exchange of which the broker is also a  member.
Under  applicable Delaware  law, a  broker non-vote will  have no  effect on the
outcome of  the election  of directors  and will  be the  equivalent of  a  vote
against  the  amendment  of  the  1992  Long-Term  Incentive  Plan  but  will be
considered present for purposes of determining a quorum.
 
                             PRINCIPAL STOCKHOLDERS
 
     The only  persons known  by the  Board of  Directors to  be the  beneficial
owners  of more than five percent of  the outstanding shares of Common Stock, as
of March 31, 1996, are indicated below:
 
<TABLE>
<CAPTION>
                                                                       AMOUNT AND
                                                                       NATURE OF
                        NAME AND ADDRESS OF                            BENEFICIAL      PERCENT
                          BENEFICIAL OWNER                             OWNERSHIP       OF CLASS
- --------------------------------------------------------------------   ----------      --------
 
<S>                                                                    <C>             <C>
Donald P. Moriarty .................................................     773,500(1)      8.49%
  c/o McGrath, Doyle & Phair
  150 Broadway
  New York, New York 10038
Dimensional Fund Advisors Inc. .....................................     602,300(2)      6.61%
  1299 Ocean Avenue
  Santa Monica, CA 90401
</TABLE>
 
- ------------
 
(1) Information regarding Donald P.  Moriarty was obtained  from a Schedule  13D
    filed  by him with the Securities and Exchange Commission. Such Schedule 13D
    states that Mr.  Moriarty is deemed  to be the  beneficial ownership of  and
    have sole dispositive power over the 773,500 shares of Common Stock and that
    such  shares are  held by  Mr. Moriarty, his  family members,  and Twin Oaks
    Partners, a partnership in which he is a general partner.
 
(2) Information regarding  Dimensional Fund  Advisors Inc.  ('Dimensional')  was
    obtained  from a Schedule 13G,  as amended, filed by  it with the Securities
    and Exchange  Commission.  Such  Schedule 13G  states  that  Dimensional,  a
    registered  investment advisor, is deemed to  be the beneficial ownership of
    and have sole  dispositive power over  the 602,300 shares  of Common  Stock;
    that  such shares are held in  portfolios of DFA Investment Dimensions Group
    Inc., an open-end investment company registered under the Investment Company
    Act of 1940 (the 'Fund') or in a series of the DFA Investment Trust Company,
    a Delaware  business  trust  (the  'Trust'), or  DFA  Group  Trust  and  DFA
    Participating  Group  Trust,  investment  vehicles  for  qualified  employee
    benefit plans, as to all of which Dimensional serves as investment  manager;
    that Dimensional disclaims beneficial ownership of such shares; that persons
    who  are officers of Dimensional also serve  as officers of the Fund and the
    Trust; and that in  their capacity as  officers of the  Fund and the  Trust,
    these  persons vote 227,800 shares owned by  the Fund and 4,800 shares owned
    by the Trust (a total of 369,700 shares), and Dimensional is deemed to  have
    sole voting power over such shares.
 
                                       2
 
<PAGE>
<PAGE>
                                  PROPOSAL ONE
                             ELECTION OF DIRECTORS
 
     At  the meeting,  seven Directors  are to be  elected, each  to hold office
(subject to the Corporation's By-Laws) until  the next annual meeting and  until
his  successor has  been elected  and qualified.  Each nominee  has consented to
being named as a nominee in this Proxy Statement and to serve if elected. If any
nominee listed in  the table  below should  become unavailable  for any  reason,
which management does not anticipate, the proxy will be voted for any substitute
nominee  or nominees who  may be selected by  the management prior  to or at the
meeting, or, if no substitute is selected  by the management prior to or at  the
meeting,  for a motion  to reduce the membership  of the Board  to the number of
nominees available. Directors will be elected by a plurality of the votes  cast.
There  are no  family relationships between  any of the  directors and executive
officers of  the Company.  The  information concerning  the nominees  and  their
security holdings has been furnished by them to the Corporation.
 
<TABLE>
<CAPTION>
                                                          PRINCIPAL OCCUPATION DURING
                                                            THE PAST FIVE YEARS, ANY                     YEAR FIRST
                                                        OFFICE HELD IN THE CORPORATION,                   ELECTED
              NAME                  AGE                     AND OTHER DIRECTORSHIPS                      A DIRECTOR
- ---------------------------------   ---   ------------------------------------------------------------   ----------
<S>                                 <C>   <C>                                                            <C>
John W. Jackson..................   51    Chairman  of the  Board and  Chief Executive  Officer of the      1996
                                            Corporation since January, 1996. Founder and President  of
                                            Gemini  Medical,  a consulting  firm which  specialized in
                                            services to  start-up  medical  device  and  biotechnology
                                            companies  and  investment advice,  from February  1991 to
                                            January 1996; President  of the  worldwide Medical  Device
                                            Division  of  American  Cyanamid  from  February  1986  to
                                            January 1991; various  international positions,  including
                                            Vice  President-International  for American  Cyanamid from
                                            1978 to 1986; several human health marketing positions  at
                                            Merck & Company from 1971 to 1978.
Sol J. Barer.....................   49    President  of the  Corporation since October  1993 and Chief      1994
                                            Operating Officer  of the  Corporation since  March  1994;
                                            Senior  Vice President -- Science  and Technology and Vice
                                            President/General   Manager   Chiral   Products   of   the
                                            Corporation  from October  1990 to October  1993; and Vice
                                            President -- Technology of the Corporation from  September
                                            1987 to October 1990.
Frank T. Cary....................   75    Chairman  of the Executive Committee of the Board since June      1986
                                            1990; Chairman of the Board  of the Corporation from  July
                                            1986  to July 1990; Former Chairman of the Board and Chief
                                            Executive  Officer  of  International  Business   Machines
                                            Corporation,    a   computer    and   business   equipment
                                            manufacturer,  from  1973  to  1981;  director  of  Cygnus
                                            Therapeutic  Systems, ICOS Corporation,  Lincare Inc., SPS
                                            Transaction Services,  Inc., Lexmark  International,  SEER
                                            Technologies, Inc., ONCORx and Teltrend, Inc.
</TABLE>
 
                                       3
 
<PAGE>
<PAGE>
 
<TABLE>
<CAPTION>
                                                          PRINCIPAL OCCUPATION DURING
                                                            THE PAST FIVE YEARS, ANY                     YEAR FIRST
                                                        OFFICE HELD IN THE CORPORATION,                   ELECTED
              NAME                  AGE                     AND OTHER DIRECTORSHIPS                      A DIRECTOR
- ---------------------------------   ---   ------------------------------------------------------------   ----------
<S>                                 <C>   <C>                                                            <C>
Arthur Hull Hayes, Jr............   62    President   and  chief  operating   officer  of  MediScience      1995
                                            Associates, Inc.,  a  consulting organization  that  works
                                            with   pharmaceutical  firms,   biomedical  companies  and
                                            foreign  governments,   since   July  1991;   partner   in
                                            IssueSphere,  a public affairs firm that focuses on health
                                            science  issues,   since  November   1995;  professor   in
                                            medicine,  pharmacology and family  and community medicine
                                            at  New  York  Medical  College;  clinical  professor   of
                                            medicine   and  pharmacology  at  the  Pennsylvania  State
                                            University  College  of  Medicine;  President  and   Chief
                                            Executive  Officer of  E.M. Pharmaceuticals, a  unit of E.
                                            Merck AG, from 1986 to 1990; Commissioner of the U.S. Food
                                            and Drug  Administration from  1981 to  1983; director  of
                                            Myriad Genetics, Inc. and NaPro BioTherapeutics, Inc.
Richard C. E. Morgan.............   51    A  general partner  of Wolfensohn  Partners L.P.,  a venture      1987
                                            capital partnership and the general partner of  Wolfensohn
                                            Associates  L.P.,  since 1986;  Chairman,  Chief Executive
                                            Officer, and director of Lasertechnics, Inc.; Chairman and
                                            director  of   MediSense,   Inc.;   director   of   SEQUUS
                                            Pharmaceuticals, Inc.; and Chairman and director of Quidel
                                            Corp.
Walter L. Robb...................   68    Private consultant and President of Vantage Management Inc.,      1992
                                            a  consulting and investor services company, since January
                                            1993; Senior  Vice President  for Corporate  Research  and
                                            Development  of General  Electric Company,  a consumer and
                                            industrial products company and broadcaster, and a  member
                                            of  its Corporate Executive Council  from 1986 to December
                                            1992; Chairman of the Board of Neopath, Inc.; director  of
                                            Marquette Electronics, Inc. and Cree Research Inc.
Lee J. Schroeder.................   67    President    of   Lee   Schroeder    &   Associates,   Inc.,      1995
                                            pharmaceutical business consultants  since 1985;  director
                                            of  FirsTier Bank Lincoln,  N.A., Harris Technology Group,
                                            Inc., Bryan Memorial  Hospital, MGI Pharmaceutical,  Inc.,
                                            Ascent  Pharmaceuticals, and  Interneuron Pharmaceuticals,
                                            Inc.
</TABLE>
 
                                       4
 
<PAGE>
<PAGE>
BENEFICIAL OWNERSHIP OF DIRECTORS AND MANAGEMENT
 
     The table below sets forth the beneficial ownership of the Common Stock  as
of  March 31, 1996 (i) by each director,  (ii) by each of the executive officers
named in  the 'Summary  Compensation  Table,' and  (iii)  by all  directors  and
executive officers of the Corporation as a group.
 
<TABLE>
<CAPTION>
                                                                                   AMOUNT AND NATURE OF
                                                                                  BENEFICIAL OWNERSHIP OF
                                                                                      COMMON STOCK AS        PERCENT
                NAME                                  POSITION                       OF MARCH 31, 1996       OF CLASS
- ------------------------------------  -----------------------------------------   -----------------------    --------
 
<S>                                   <C>                                         <C>                        <C>
John W. Jackson.....................  Chairman of the Board and Chief Executive            83,733(1)(2)        *
                                        Officer
Sol J. Barer........................  President, Chief Operating Officer, and a           153,334(1)            1.7%
                                        Director
Frank T. Cary.......................  Director                                             65,000(1)           *
Arthur Hull Hayes, Jr...............  Director                                               --  (1)           *
Richard C.E. Morgan.................  Director                                            292,055(1)(3)         3.2%
Walter L. Robb......................  Director                                             21,000(1)           *
Lee J. Schroeder....................  Director                                              5,000(1)           *
Richard G. Wright...................  Former Chairman of the Board and Chief              150,000(1)            1.6%
                                        Executive Officer
All directors and current executive
  officers of the Corporation as a group (seven persons).......................           620,122(4)            6.8%
</TABLE>
 
- ------------
 
*  Less than one percent (1%).
 
(1) Includes  shares of Common Stock which  the directors and executive officers
    had the right to acquire through the  exercise of options within 60 days  of
    March   31,  1996,   as  follows:  John   W.  Jackson  --   83,333;  Sol  J.
    Barer --  153,334 shares;  Frank  T. Cary  --  40,000 shares;  Richard  C.E.
    Morgan  -- 35,000 shares;  Walter L. Robb  -- 13,000 shares;  and Richard G.
    Wright -- 150,000 shares. Does not include shares of Common Stock which  the
    directors  and  executive  officers had  the  right to  acquire  through the
    exercise of options  not exercisable within  60 days of  March 31, 1996,  as
    follows:  John  W. Jackson  -- 166,667;  Sol  J. Barer  -- 94,486;  Frank T.
    Cary  --  21,000;   Arthur  Hull   Hayes,  Jr.  --   20,000;  Richard   C.E.
    Morgan   --   21,000   shares;   Walter  L.   Robb   --   21,000;   and  Lee
    Schroeder -- 21,000 shares. Includes as  to Walter L. Robb, 4,000 shares  of
    Common  Stock subject to restricted stock awards, 1,334 of which shares were
    subject to forfeiture as of March 31, 1996.
 
(2) Includes 400 shares owned by Donald M.  Jackson, the son of Mr. Jackson,  as
    to which shares Mr. Jackson disclaims beneficial ownership.
 
(3) Includes 252,055 shares of Common Stock owned by Wolfensohn Associates L.P.,
    of  which Wolfensohn Partners L.P.  is the general partner.  Mr. Morgan is a
    general partner of Wolfensohn Partners L.P. Mr. Morgan's indirect  pecuniary
    interest  in  such  shares  of  Common Stock,  within  the  meaning  of Rule
    16a-1(a)(2)(ii)(B)  under   the  Securities   Exchange  Act   of  1934,   is
    significantly less than the amount disclosed. Mr. Morgan otherwise disclaims
    beneficial  ownership of  such shares  of Common  Stock owned  by Wolfensohn
    Associates L.P.
 
(4) Includes or  excludes,  as  the case  may  be,  shares of  Common  Stock  as
    indicated in the preceding footnotes.
 
                                       5
 
<PAGE>
<PAGE>
DIRECTOR COMPENSATION
 
     Directors do not receive salaries or cash fees for serving as directors nor
do  they receive any  cash compensation for serving  on committees; however, all
members of  the Board  of Directors  who are  not employees  of the  Corporation
('Non-Employee  Directors') are reimbursed  for their expenses  for each meeting
attended and  are  eligible  to  receive stock  options  pursuant  to  the  1995
Non-Employee Directors' Plan (the '1995 Directors' Plan').
 
     The  1995 Directors' Plan was adopted by the Board of Directors on April 5,
1995, and approved by Corporation's stockholders  at the 1995 Annual Meeting  of
Stockholders. The 1995 Directors' Plan provides for the granting to Non-Employee
Directors  of non-qualified  options to purchase  an aggregate of  not more than
250,000 shares (subject to adjustment in certain circumstances) of Common Stock.
 
     Under the 1995 Directors' Plan, each  Non-Employee Director as of April  5,
1995  was granted  a non-qualified  option to  purchase 20,000  shares of Common
Stock, and  each new  Non-Employee Director  upon the  date of  his election  or
appointment  will be granted a non-qualified option to purchase 20,000 shares of
Common Stock.  These initial  options  vest in  four equal  annual  installments
commencing  on  the  first  anniversary  of  the  date  of  grant,  assuming the
Non-Employee Director remains a director.
 
     Upon the date of the 1995 Annual Meeting of Stockholders, each Non-Employee
Director was also  granted a non-qualified  option to purchase  6,000 shares  of
Common  Stock. Upon  the date  of the Annual  Meeting of  Stockholders each year
after 1995, each Non-Employee Director will be granted a non-qualified option to
purchase 10,000 shares of  Common Stock (or  a pro rata  portion thereof if  the
director  did  not serve  the  entire year  since the  date  of the  last annual
meeting). These options vest in full on the date of the first Annual Meeting  of
Stockholders  held following  the date of  the grant,  assuming the Non-Employer
Director is a director on that date.
 
     All options granted  pursuant to the  1995 Directors' Plan  will expire  no
later  than 10 years from the date of  grant and no options may be granted after
June 16, 2005. If a Non-Employee Director terminates his service on the Board of
Directors for  any  reason,  options  which were  exercisable  on  the  date  of
termination  and which have not  expired may be exercised  at any time until the
date of expiration of such options. In addition, if there is a change of control
and within  two  years thereafter,  a  director  is removed  without  cause  (as
defined) or is not nominated for election by the Corporation's stockholders, all
unvested portions of a stock option will automatically vest.
 
     In  1995,  pursuant to  the  1995 Directors'  Plan,  each of  Messrs. Cary,
Morgan, Robb  and Schroeder  received an  option to  purchase 20,000  shares  of
Common  Stock at an exercise price of $5.75  per share, the fair market value of
the stock on the date of the grant, and each also received an option to purchase
6,000 shares of Common Stock at an exercise price of $8.125 per share, the  fair
market  value of  the stock on  the date  of the grant.  Upon his  election as a
director in  December 1995,  Mr. Hayes  received an  option to  purchase  20,000
shares of Common Stock at an exercise price of $10.50 per share, the fair market
value of the stock on the date of the grant.
 
BOARD COMMITTEES AND MEMBERSHIP
 
     The Corporation has an Executive Committee of the Board of Directors, whose
current  members are Frank T. Cary, Chairman,  Sol J. Barer, John W. Jackson and
Richard C. E.  Morgan. The  Executive Committee held  no meetings  in 1995.  The
Executive  Committee has and may exercise all of the powers and authority of the
full Board of Directors of the Corporation, subject to certain exceptions.
 
                                       6
 
<PAGE>
<PAGE>
     The  Corporation  has  an  Audit  Committee  of  the  Board  of  Directors,
consisting  entirely  of outside  directors, the  current  members of  which are
Walter L.  Robb, Chairman,  Frank T.  Cary, Richard  C. E.  Morgan, and  Lee  J.
Schroeder.  The Audit Committee held one meeting in 1995. The Board of Directors
has delegated to the  Audit Committee the following  duties: reviewing with  the
independent  auditors the plans  and results of  the audit engagement; reviewing
the adequacy,  scope,  and  results  of the  internal  accounting  controls  and
procedures;  reviewing the degree of independence of the auditors; reviewing the
auditors' fees; and recommending the engagement of auditors to the full Board of
Directors.
 
     The Corporation  has a  Management Compensation  and Development  Committee
(the  'Compensation Committee') of the Board of Directors, whose current members
are Richard C.E. Morgan,  Chairman, Frank T.  Cary, Walter L.  Robb, and Lee  J.
Schroeder.   The  Compensation  Committee   held  two  meetings   in  1995.  The
Compensation Committee has  (i) the full  power and authority  to interpret  the
provisions  and  supervise the  administration of  the Corporation's  1986 Stock
Option Plan and 1992  Long-Term Incentive Plan and  to grant options outside  of
these  plans  and (ii)  the  authority to  review  all matters  relating  to the
personnel of the Corporation.
 
     The Corporation  does  not  have  a  nominating  committee.  The  Board  of
Directors  held  ten meetings  during 1995.  During 1995,  all of  the directors
attended more than 75% of the aggregate  of (i) the total number of meetings  of
the  Board of Directors and (ii) the  total number of meetings of all committees
of the Board on which such director served.
 
COMPLIANCE WITH SECTION 16(a) OF THE SECURITIES EXCHANGE ACT OF 1934
 
     Under  the  securities  laws  of  the  United  States,  the   Corporation's
directors,  executive officers, and any persons  holding more than 10 percent of
the Common Stock are required to report their ownership of Common Stock and  any
changes  in that ownership,  on a timely  basis, to the  Securities and Exchange
Commission. Based on  material provided  to the Corporation,  all such  required
reports were filed on a timely basis in 1995 except for the Initial Statement of
Beneficial   Ownership  on  Form  3  for  Dr.  Hayes,  which  report  was  filed
approximately three weeks late.
 
                  EXECUTIVE COMPENSATION AND OTHER INFORMATION
 
SUMMARY OF CASH AND CERTAIN OTHER COMPENSATION
 
     The following table contains information about the compensation paid by the
Corporation for services rendered in all capacities during the three years ended
December 31, 1995 to the Chief Executive Officer of the Corporation and each  of
the  most highly paid executive officers of the Corporation who earned more than
$100,000.
 
                                       7
 
<PAGE>
<PAGE>
                           SUMMARY COMPENSATION TABLE
 
<TABLE>
<CAPTION>
                                                                                                  LONG TERM
                                                                                                COMPENSATION
                                                                                         ---------------------------
                                                                                                   AWARDS
                                                                            ANNUAL       ---------------------------
                                                                         COMPENSATION      RESTRICTED
                                                                         ------------         STOCK         OPTIONS/
                 NAME AND PRINCIPAL POSITION                     YEAR     SALARY ($)     AWARD(S) ($)(1)    SARS (#)
- --------------------------------------------------------------   ----    ------------    ---------------    --------
<S>                                                              <C>     <C>             <C>                <C>
Richard G. Wright ............................................   1995      $486,250(2)       --                   0
  Former Chief Executive Officer and                             1994       195,288(3)       --             150,000
  Chairman of the Board                                          1993        --              --               --
Sol J. Barer .................................................   1995      $200,000          --                   0
  President and Chief Operating Officer                          1994       197,000          --              54,080
                                                                 1993       180,000          --              30,000
</TABLE>
 
- ------------
 
(1) No restricted stock awards  were granted to either  Mr. Wright or Dr.  Barer
    during  the last three years, and neither  Mr. Wright nor Dr. Barer held any
    shares of Common Stock  subject to restricted stock  awards at December  31,
    1995.
 
(2) Pursuant  to his  employment arrangement with  the Corporation,  in 1995 Mr.
    Wright  was  paid  a  salary  of  $236,250.  Mr.  Wright  retired  from  the
    Corporation on December 31, 1995 and received a lump-sum payment of $250,000
    in  January, 1996.  The Board of  Directors also amended  Mr. Wright's stock
    option agreement to  permit him to  retain 50,000 options,  which vested  as
    scheduled in March 1996 and which otherwise would have been canceled, and to
    permit  Mr. Wright to exercise all of his  options over the ten year life of
    the original  grant, rather  than within  three months  of the  date of  his
    retirement as provided for originally in his option agreement.
 
(3) Mr.  Wright commenced  his employment  with the  Corporation in  March 1994.
    Accordingly, the  1994  number  reflects  a  partial  year's  salary  and  a
    relocation allowance in the amount of $18,750.
 
EMPLOYMENT AGREEMENTS AND TERMINATION OF EMPLOYMENT ARRANGEMENTS
 
     Sol  J. Barer, President and Chief Operating Officer of the Corporation, is
a party to an  employment agreement with the  Corporation expiring in  September
1996.  Pursuant  to  such agreement,  Dr.  Barer  receives an  annual  salary of
$200,000,  subject  to  increase  upon  annual  review.  Except  under   certain
circumstances,  the  Corporation may  not  terminate this  agreement  without 12
months' prior  notice  to  Dr.  Barer. Additionally,  pursuant  to  Dr.  Barer's
employment  agreement, he will  be entitled to  receive a cash  payment equal to
2.99 times  his base  salary in  the event  of the  termination of  Dr.  Barer's
employment  as a result  of (i) his  disability, (ii) the  occurrence of certain
events subsequent to a change in control of the Corporation (as defined in  such
agreement),  or  (iii)  certain material  breaches  by the  Corporation  of such
agreement.
 
     If during the two-year period following a change in control (as defined  in
the  Corporation's 1992 Long-Term Incentive Plan)  of the Corporation, (i) there
is a change  in an employee's  title or a  significant change in  the nature  or
scope  of his  employment or  duties and  such person  terminates his employment
within 90 days  following such change  or (ii) an  employee's employment by  the
Corporation  is terminated without  cause (as defined), then  all of the options
held by  such  employee  then  outstanding will  become  immediately  and  fully
exercisable,  and all restrictions applicable  to restricted stock automatically
will terminate.
 
                                       8
 
<PAGE>
<PAGE>
STOCK OPTIONS
 
     No stock options or stock appreciation rights ('SARs') were granted to  the
named  executive officers during the year ended December 31, 1995 and there were
no options or SARs exercised  by such officers during  1995. As of December  31,
1995 no SARs were outstanding.
 
     The  following table sets forth information with respect to options held as
of December 31, 1995 by each of the named executive officers.
 
                         FISCAL YEAR-END OPTION VALUES
 
<TABLE>
<CAPTION>
                                                               NUMBER OF UNEXERCISED            VALUE OF UNEXERCISED
                                                                      OPTIONS                   IN-THE-MONEY OPTIONS
                                                               AT FISCAL YEAR-END (#)        AT FISCAL YEAR-END ($)(1)
                                                            ----------------------------    ----------------------------
                          NAME                              EXERCISABLE    UNEXERCISABLE    EXERCISABLE    UNEXERCISABLE
- ---------------------------------------------------------   -----------    -------------    -----------    -------------
 
<S>                                                         <C>            <C>              <C>            <C>
Richard G. Wright........................................     100,000          50,000        $ 650,000       $ 325,000
Sol J. Barer.............................................     126,974          48,346          637,078         266,262
</TABLE>
 
- ------------
 
(1) Represents the difference  between the  closing market price  of the  Common
    Stock  as reported by NASDAQ  on December 31, 1995  of $13.375 per share and
    the exercise  price per  share  of in-the-money  options multiplied  by  the
    number of shares underlying the in-the-money options.
 
CERTAIN TRANSACTIONS
 
     For  a  discussion  of  certain  transactions  see  'Compensation Committee
Interlocks and Insider Participation.'
 
REPORT OF THE MANAGEMENT COMPENSATION AND DEVELOPMENT COMMITTEE
 
     The  Compensation   Committee   determines  the   Corporation's   executive
compensation policies. The Compensation Committee determines the compensation of
the   Corporation's   executive   officers  and   approves   and   oversees  the
administration of incentive  compensation programs for  all employees  including
executive  officers. The  Compensation Committee  is composed  solely of outside
directors.
 
EXECUTIVE COMPENSATION POLICIES AND PROGRAMS
 
     The Corporation's executive compensation program is part of a  company-wide
program  covering all employees. The program's goals are to attract, retain, and
motivate  employees,  and  it  utilizes  incentives  such  that  employees   and
stockholders  share the same risks. The compensation program is designed to link
compensation to performance. A portion  of each employee's compensation  relates
to  the grant  of stock  options, and  such grants  are based  on the successful
attainment of strategic corporate, business  unit, and individual goals. As  the
Corporation  has not as yet attained  significant commercial revenues, goals are
set which relate to the successful attainment of strategic events.
 
     The Corporation does not have a pension plan or other capital  accumulation
program. Grants of stock options are therefore of great importance to executives
as  well as all  employees. Any long-term  value to be  derived from such grants
will be consistent with stockholder gains.
 
                                       9
 
<PAGE>
<PAGE>
     Executive and  employee  compensation includes  salary,  employment-related
benefits, and long-term incentive compensation:
 
     Salary.   Salaries  are   set  competitively  relative   to  the  chemical,
biotechnology, and  pharmaceutical  industries  --  industries  with  which  the
Corporation competes for its highly skilled personnel. Individual experience and
performance  is  considered  when setting  salaries  within the  range  for each
position. Annual reviews are held and  adjustments are made based on  attainment
of individual goals.
 
     Benefits.  All employees are eligible for similar benefits, such as health,
disability, and life insurance.
 
     Long-Term Incentive  Compensation.  An incentive  compensation  program  is
established  annually.  The  purpose of  this  program is  to  provide financial
incentives to executives  and employees  to achieve  annual corporate,  business
unit,  and individual  goals. The  incentive program  also aligns  executive and
employee interests with those of stockholders by using grants of stock  options.
Such  grants vest  over time thereby  encouraging continued  employment with the
Corporation. The size of  grants is tied  to comparative biotechnology  industry
practices. To determine such comparative data, the Corporation relies on outside
compensation  consultants, the Corporation's auditors,  and third party industry
surveys.
 
     Under the Corporation's 1995 incentive  program, it was agreed, subject  to
the  achievement  of  certain  goals  in  1995  by  the  Corporation,  that  the
Corporation would grant at  a future date options  to purchase shares of  common
stock.  A  similar  incentive  program  has  been  designed  for  1996  based on
attainment of corporate,  business unit,  and individual goals.  The program  is
open  to all regular  full-time employees, other than  the executive officers of
the Corporation.
 
     Chief Executive Officer Compensation. Pursuant to Mr. Wright's  arrangement
with  the Corporation  entered into  on March  18, 1994,  Mr. Wright  received a
salary of  $236,250  for  1995. Mr.  Wright  did  not participate  in  the  1995
Incentive  Program. Mr. Wright's  long-term incentive derived  from the grant of
stock options to purchase 150,000 shares of  Common Stock awarded to him at  the
time  he  began serving  as  Chief Executive  Officer.  In consideration  of his
service to the Corporation,  the Board of Directors  also approved a payment  to
Mr.  Wright of $250,000 upon his retirement from the Corporation at December 31,
1995. The Board of Directors also amended Mr. Wright's stock option agreement to
permit him to retain 50,000 options, which vested as scheduled in March 1996 and
which otherwise would have been canceled,  and to permit Mr. Wright to  exercise
all  of his options  over the ten year  life of the  original grant, rather than
within three months of the date of his retirement as provided for originally  in
his option agreement.
 
                                          Members of the Management Compensation
                                          and Development Committee
 
                                          RICHARD C. E. MORGAN, Chairman
                                          FRANK T. CARY
                                          WALTER L. ROBB
                                          LEE J. SCHROEDER
 
COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION
 
     The current members of the Compensation Committee are Richard C. E. Morgan,
Chairman,  Frank T. Cary,  Walter L. Robb,  and Lee J.  Schroeder. Richard C. E.
Morgan is a general  partner of Wolfensohn Partners  L.P., which is the  general
partner  of Wolfensohn Associates L.P. In connection with the purchase of Common
Stock  in   a   private   placement  in   1986,   Wolfensohn   Associates   L.P.
 
                                       10
 
<PAGE>
<PAGE>
received  certain demand and 'piggyback' registration rights with respect to the
Common Stock purchased by it under certain conditions.
 
PERFORMANCE GRAPH
 
     The following graph shows changes over the past five years in the value  of
$100  invested in: (1) the Corporation's Common Stock; (2) the Standard & Poor's
500 Index; and (3) the NASDAQ Pharmaceutical Index.
 
     The graph shows  the value of  $100 invested  on December 31,  1995 in  the
Corporation's  Common Stock or  in one of the  indexes, as applicable, including
reinvestment of dividends, at December 31 for each of 1991-1995.
 

                COMPARISON OF FIVE YEAR CUMULATIVE TOTAL RETURN*
                AMOUNG CELGENE CORPORATION, THE S & P 500 INDEX
                       AND THE NASDAQ PHARMACEUTICAL INDEX


   INVESTMENT                   1990    1991    1992    1993    1994    1995

Celgene Corporation             100     235     202     108     87      206

S&P 500 Index                   100     130     140     155     157     215

Nasdaq Pharmaceutical Index     100     266     221     197     148     271

* $100 INVESTED ON 12/31/90 IN STOCK OR INDEX-
  INCLUDING REINVESTMENT OF DIVIDENDS,
  FISCAL YEAR ENDING DECEMBER 31.


                                       11
 
<PAGE>
<PAGE>
                                  PROPOSAL TWO
                       APPROVAL OF AMENDMENTS TO THE 1992
                            LONG-TERM INCENTIVE PLAN
 
     The stockholders of the Corporation are asked to approve certain amendments
to the Corporation's 1992 Long-Term  Incentive Plan (the '1992 Incentive  Plan')
to  ensure that stock  options and stock  appreciation rights granted thereunder
continue to qualify  as performance-based compensation  for purposes of  Section
162(m)  of the Internal Revenue Code of 1986, as amended (the 'Code'). The Board
of Directors approved these amendments to  the 1992 Incentive Plan at a  meeting
of  the  Board of  Directors  on January  8, 1996,  subject  to the  approval of
stockholders. The affirmative vote of the holders of at least a majority of  the
outstanding  shares of Common Stock  present and entitled to  vote at the annual
meeting is required  to approve the  amendment of the  1992 Incentive Plan.  THE
BOARD  OF DIRECTORS RECOMMENDS  THAT THE STOCKHOLDERS VOTE  THEIR SHARES FOR THE
PROPOSAL TO APPROVE THE AMENDMENT OF THE 1992 INCENTIVE PLAN.
 
BACKGROUND OF THE PROPOSAL TO AMEND THE 1992 INCENTIVE PLAN
 
     The final Treasury Department regulations under Section 162(m) of the  Code
were  issued on December 20, 1995. Under Section 162(m), an employer's deduction
for compensation  paid to  certain  'covered employees'  (defined as  the  Chief
Executive  Officer and the four most  highly compensated officers other than the
Chief Executive Officer for the  taxable year and who  are employed on the  last
day  of the taxable year) of publicly held corporations is limited to $1 million
in a taxable year. Certain types of compensation such as 'qualified  performance
based compensation,' however, are not subject to the deduction limit and are not
taken into account in determining whether an executive's compensation exceeds $1
million.
 
     Compensation qualifies for the exception for performance based compensation
if  the following requirements are met: (a) it  is paid solely on account of the
attainment of one or more performance  goals; (b) the relevant performance  goal
is  preestablished by a committee consisting  of two or more 'outside directors'
(as defined  in  Code Section  162(m)  and the  Treasury  Department  Regulation
thereunder)  (the 'Compensation Committee'); (c)  the material terms under which
the compensation is to be paid, including the performance goals, are  adequately
disclosed  to and approved by the shareholders of the publicly held corporation;
and (d) the Compensation  Committee certifies that prior  to the payment of  the
compensation, the performance goals and all other material terms were satisfied.
 
     Generally,   compensation  attributable  to  a  stock  option  or  a  stock
appreciation right is deemed to be qualified performance based compensation  if:
(a)  the grant  or award  is made  by the  Compensation Committee;  (b) the plan
states the maximum number of shares with  respect to which the stock options  or
stock  appreciation rights  may be  granted to  any employee  during a specified
period; and (c) under the terms of  the option or stock appreciation right,  the
amount  of compensation that  an employee may  receive under the  grant is based
solely on  an increase  in  value of  the  stock after  the  date of  the  grant
(however,  if a stock option  is granted for less than  the fair market value of
the stock at the time of grant, no compensation attributable to that option will
be considered qualified  performance based compensation).  While it is  intended
that  the award of  stock options and  stock appreciation rights  under the 1992
Incentive Plan will satisfy the requirements  of Section 162(m) of the Code  for
performance  based compensation so that the income recognized in connection with
such awards will not be included in a 'covered employee's' compensation for  the
purpose  of determining  whether such  covered recipient's  compensation exceeds
$1,000,000,  due  to   the  limited   evidence  that  exists,   the  effect   of
 
                                       12
 
<PAGE>
<PAGE>
Section  162(m)  on the  deductibility of  such 'covered  employee' compensation
cannot be ascertained with certainty.
 
SUMMARY OF THE 1992 INCENTIVE PLAN
 
     The following description of the 1992 Incentive Plan is a summary that does
not give effect to any of the  proposed amendments. The Plan was adopted by  the
Board  of Directors on March 13, 1992 and was approved at the Corporation's 1992
Annual Meeting of Stockholders.
 
     Types of  Awards  and Shares  Subject  to  Plan. The  1992  Incentive  Plan
provides   for  the  granting   of  optional  restricted   stock  awards,  stock
appreciation rights ('SARs'), performance  awards, and other stock-based  awards
(the 'Plan Awards') to employees and officers of the Corporation to purchase not
more  than 1,000,000 shares of Common Stock, subject to adjustment under certain
circumstances. As  of March  31, 1996,  options to  purchase 606,146  shares  of
Common  Stock have been granted under the 1992 Incentive Plan at exercise prices
ranging from  $6.875  to  $16.75.  Of the  options  granted,  94,707  have  been
cancelled, leaving a total of 488,561 available for future grants under the 1992
Incentive  Plan. A grant of options to purchase 72,500 shares of Common Stock at
a price of $16.75  to Sol J.  Barer in February 1996  is subject to  stockholder
approval  of the proposed  amendments to the  1992 Incentive Plan.  As of May 3,
1996, the market value of a share of Common Stock was $15.00.
 
     Purpose. The 1992 Incentive Plan is  designed to provide a means of  giving
existing  and  potential  selected  management and  key  employees  an increased
opportunity to  acquire  a  proprietary interest  in  the  Corporation,  thereby
maintaining   and  strengthening  their  desire  to  remain  with  or  join  the
Corporation.
 
     Administration. The 1992  Incentive Plan is  administered by the  Committee
which  consists of  two or  more persons  appointed by  the Board  of Directors.
Subject to any  general guidelines established  by the Board  of Directors,  the
Committee has full and final authority to determine the persons to whom, and the
time or times at which, Plan Awards are granted, the number of shares subject to
each Plan Award, the number of options which shall be treated as incentive stock
options,  the duration of  each option, the  specific restrictions applicable to
restricted stock awards and other Plan Awards, and other terms and provisions of
each Plan Award. In determining persons  who are to receive options,  restricted
stock  awards, or SARs and the number of shares to be covered by each option and
restricted stock  award,  the  Committee  considers,  among  other  things,  the
person's position, responsibilities, service, accomplishments, and such person's
present  and future  value to  the Corporation.  The 1992  Incentive Plan became
effective on March 13, 1992. No awards will be granted under the 1992  Incentive
Plan  after March 12, 2002, but unless  otherwise expressly provided in the 1992
Incentive Plan or an awards agreement, a Plan Award may extend beyond such date.
 
     Stock Options. The term  of options granted under  the 1992 Incentive  Plan
are  fixed by the Committee; however, such term may not exceed 10 years from the
date of grant  (or in the  case of an  incentive stock option  granted to a  10%
stockholder,  5 years from the  date of grant). The  purchase price per share of
Common Stock purchasable under any option will not be less than 100% of the fair
market value of the stock on the date of grant of the option (or, in the case of
an incentive stock option granted to a 10% stockholder, 110% of the fair  market
value).  The Committee may provide  that options will be  exercisable in full at
any time or from time to time during the option term or provide for the exercise
thereof in such installments at such times as the Committee determines,  subject
to the 'Change in Control' provisions of the 1992 Incentive Plan. Options may be
exercised  by payment in full of the purchase price, either in cash or, in whole
or   in   part,   in   Common   Stock   having   a   fair   market   value    on
 
                                       13
 
<PAGE>
<PAGE>
the  date the option  is exercised equal  to the option  price, provided that no
stock may be  used by  a participant  as payment for  the exercise  price of  an
option  unless  the stock  has been  held by  the participant  for at  least six
months. Therefore, the  1992 Incentive Plan  permits 'pyramiding' by  optionees.
Pyramiding  occurs  when  an  optionee  exercises  stock  options  in increasing
portions by  using each  portion and  the appreciation  inherent in  the  shares
obtained  to exercise  a larger portion  of the option.  Theoretically, by using
this approach, an optionee could purchase one share for cash and continue to use
the shares  obtained  to  exercise  the entire  option  in  successively  larger
exercises.  The result could be that the optionee would receive shares of Common
Stock equal  in  value to  the  differential  between market  price  and  option
purchase price with only a minimal cash payment.
 
     Stock Appreciation Rights. Upon exercise of an SAR, the holder thereof will
be entitled to receive the excess of the fair market value (calculated as of the
exercise  date) of a specified  number of shares over  the exercise price of the
SAR. The exercise price (which may not be less than the fair market value of the
shares on the date of  grant) and other terms of  the SAR will be determined  by
the  Committee. Payment by  the Corporation upon  exercise of an  SAR will be in
cash, stock, or  other property, or  any combination thereof,  as the  Committee
determines.  Unless  otherwise determined  by the  Committee, any  related stock
option will  no  longer be  exercisable  to the  extent  that an  SAR  has  been
exercised,  and the exercise or termination of an option will cancel the related
SAR (in the case of the exercise, to the extent thereof).
 
     Restricted Stock. Restricted  stock awards may  not be disposed  of by  the
recipient  until  certain  restrictions  established  by  the  Committee  lapse.
Recipients will not  be required to  provide cash consideration  other than  any
minimum  amount required by law. Recipients will have with respect to restricted
stock awards all of  the rights of a  stockholder of the Corporation,  including
the right to vote the shares and the right to receive any cash dividends, unless
the  Committee otherwise determines.  Upon termination of  employment during the
restriction period, the restricted stock award will be forfeited, in whole or in
part, subject to such exceptions, if any, as may be authorized by the Committee.
 
     Performance Awards. From time  to time, the Committee  may select a  period
during which performance criteria approved by the Committee will be measured for
the  purpose of  determining the  extent to which  a performance  award has been
earned. Performance awards may be denominated  or payable in Plan Awards,  cash,
or other property.
 
     Other  Stock-Based Awards.  The Committee  is also  authorized to  grant to
participants, either alone or in addition to other Plan Awards granted under the
1992 Incentive Plan, awards of stock and  other awards that are valued in  whole
or  in part by reference to, or are otherwise based on, the Common Stock ('other
stock-based awards').  Other stock-based  awards may  be paid  in Common  Stock,
cash,  other  Plan  Awards, or  any  other  form of  property  as  the Committee
determines. Other stock-based  awards will contain  provisions dealing with  the
disposition  of  the  award  if  a  participant's  employment  terminates before
exercise, realization, or payment of the award.
 
     Adjustments and Amendments of the  1992 Incentive Plan. Adjustments in  the
1992  Incentive Plan and  in outstanding options  will be made  to reflect stock
dividends, recapitalization, and similar events. The Board of Directors has  the
right  to amend,  suspend, or  terminate the  1992 Incentive  Plan at  any time;
provided, however, that  unless first  duly approved  by the  holders of  Common
Stock  entitled to vote thereon, no amendment or  change may be made in the 1992
Incentive Plan: (a)  increasing the total  number of shares  that may be  issued
under  the 1992 Incentive  Plan; (b) changing  the eligibility requirements; (c)
changing the purchase price previously specified  for the shares subject to  the
options;  or (d) extending the period during which Plan Awards may be granted or
exercised under the 1992
 
                                       14
 
<PAGE>
<PAGE>
Incentive Plan; or (e) changing the method of calculating payments in respect of
SARs. The 1992 Incentive Plan is not  subject to any of the requirements of  the
Employee  Retirement Income Security Act of 1974, as amended. The 1992 Incentive
Plan is not, nor  is it intended  to be, qualified under  Section 401(a) of  the
Code.
 
     Change  in  Control. If  during  a two-year  period  following a  change in
control of the Corporation (as defined in the 1992 Incentive Plan), (i) there is
a change in an employee's title or  a significant change in the nature or  scope
of  his employment or duties and such person terminates his employment within 90
days following such change or (ii) the recipient's employment by the Corporation
is terminated without cause  (as defined in the  1992 Incentive Plan), then  all
options,  SARs, and performance  awards outstanding will  become immediately and
fully exercisable, and  all restrictions applicable  to restricted stock  awards
will automatically terminate.
 
     Non-Assignability  of  Plan  Awards. No  Plan  Award may  be  assignable or
transferable by the  recipient, except by  will or  by the laws  of descent  and
distribution,  provided that such restriction on the transfer or assignment of a
restricted stock award shall expire upon  the date of expiration of the  related
restriction  period.  During the  lifetime of  a recipient,  Plan Awards  may be
exercisable only by  him or  his personal  representative or  guardian. No  Plan
Award  or interest  therein may  be pledged,  attached, or  otherwise encumbered
other than in favor of the Corporation.
 
     Certain Federal Income Tax Consequences.  The principal Federal income  tax
consequences  with respect to  stock options, SARs,  and restricted stock awards
granted pursuant to the  1986 Plan, the 1992  Incentive Plan, or the  Directors'
Plan are summarized below:
 
          Incentive  Stock  Options. Certain  options granted  or to  be granted
     under the 1986  Plan or  the 1992 Incentive  Plan will  be incentive  stock
     options  as defined  in the  Code, provided  that such  options satisfy the
     requirements under the Code therefor. In general, neither the grant nor the
     exercise of an incentive stock option will result in taxable income to  the
     optionee  or  a deduction  to the  Corporation. The  sales of  Common Stock
     received pursuant to  the exercise  of an  option which  satisfied all  the
     requirements  of an incentive  stock option, as well  as the holding period
     requirement described below,  will result  in a long-term  capital gain  or
     loss to the optionee equal to the difference between the amount realized on
     the sale and the option price and will not result in a tax deduction to the
     Corporation. To receive incentive stock option treatment, the optionee must
     not  dispose of the Common  Stock purchased pursuant to  the exercise of an
     option either (i)  within two years  after the option  is granted, or  (ii)
     within one year after the date of exercise.
 
          If  all requirements for  incentive stock option  treatment other than
     the holding period rules  are satisfied, the recognition  of income by  the
     optionee  is  deferred  until  disposition of  the  Common  Stock,  but, in
     general, any gain (in an amount equal to the lesser of (i) the fair  market
     value  of the  Common Stock on  the date  of exercise (or,  with respect to
     officers and directors, the date that  sale of such stock would not  create
     liability ('Section 16(b) liability') under Section 16(b) of the Securities
     Exchange Act of 1934) minus the option price or (ii) the amount realized on
     the  disposition minus the option price) is treated as ordinary income. Any
     remaining gain is treated as long-term or short-term capital gain depending
     on the optionee's holding period for the stock disposed of. The Corporation
     generally will be entitled to a deduction at that time equal to the  amount
     of ordinary income realized by the optionee.
 
          Each  of the 1986  Plan and the  1992 Incentive Plan  provides that an
     optionee may pay for Common Stock  received upon the exercise of an  option
     (including an incentive stock option) with other shares of Common Stock. In
     general,   an   optionee's  transfer   stock   acquired  pursuant   to  the
 
                                       15
 
<PAGE>
<PAGE>
     exercise of a 'statutory option,' which includes an incentive stock option,
     to acquire other  stock in  connection with  the exercise  of an  incentive
     stock option may result in ordinary income if the transferred stock has not
     met  the  minimum  statutory  holding period  necessary  for  favorable tax
     treatment as  an  incentive  stock  option. For  example,  if  an  optionee
     exercises  an  incentive stock  option and  uses the  stock so  acquired to
     exercise another  incentive  stock option  with  the two-year  or  one-year
     holding  periods discussed above, the  optionee may realize ordinary income
     under the rules summarized above.
 
          In addition, (i) any entitlement to a tax deduction on the part of the
     Corporation is  subject to  the applicable  Federal tax  rules  (including,
     without limitation, Code Section 162(m) regarding the $1,000,000 limitation
     on  deductible  compensation),  (ii)  the  exercise  of  an  ISO  may  have
     implications in the computation of alternative minimum taxable income,  and
     (iii)  in the event that the exercisability or vesting of any Plan Award is
     accelerated because of a change in  control, payments relating to the  Plan
     Awards  (or a portion thereof), either alone or together with certain other
     payments, may constitute parachute payments under Section 280G of the Code,
     which excess amounts may be subject to excise taxes.
 
          Non-Qualified Stock Options. Options which do not qualify as incentive
     stock options  are herein  referred to  as nonqualified  stock options.  An
     optionee  will realize no income at the  time he is granted a non-qualified
     stock option. Such conclusion is  predicated on the assumption that,  under
     existing  Treasury Department regulations, a non-qualified stock option, at
     the time of  its grant,  has no  readily ascertainable  fair market  value.
     Except  with respect  to the exercise  of a non-qualified  stock option for
     stock which is  'not transferable' and  subject to a  'substantial risk  of
     forfeiture,'  as described below,  ordinary income will  be realized when a
     non-qualified stock option is exercised. The amount of such income will  be
     equal  to the excess of  the fair market value on  the exercise date of the
     shares of Common  Stock issued to  an optionee over  the option price.  The
     optionee's holding period with respect to the shares acquired will begin on
     the date of exercise.
 
          Special  rules are applicable to stock which is 'not transferable' and
     subject to a 'substantial risk of  forfeiture.' In general, such stock  (i)
     is  subject to a substantial risk of  forfeiture if the optionee's right to
     full enjoyment of the stock is  conditioned upon the future performance  of
     substantial  services and  (ii) is not  transferable if  a transferee would
     take the stock subject to the same restrictions. Stock acquired pursuant to
     the exercise of  an option  as to which  a service  requirement is  imposed
     could be so treated.
 
          Unless  the optionee elects  to be taxed  at the time  of exercise (an
     '83(b) election'), the optionee will recognize ordinary income on the first
     day that the stock is either  transferable or not subject to a  substantial
     risk  of forfeiture. In  the case of  any other stock  subject to a service
     requirement, this will  depend on the  individual facts and  circumstances.
     The  ordinary income  in such case  will be  the excess of  the fair market
     value of the stock on  such date over the  option price and the  optionee's
     holding period will begin on that day.
 
          If  the optionee makes  an 83(b) election,  he will recognize ordinary
     income on the date of exercise equal to the excess of the fair market value
     of such stock at the time of exercise over the option price. The optionee's
     holding period  with  respect to  such  stock will  begin  on the  date  of
     exercise.
 
          The  tax basis of the  stock acquired upon the  exercise of any option
     will be equal to the sum of (i) the exercise price of such option and  (ii)
     the amount included in income with respect to such
 
                                       16
 
<PAGE>
<PAGE>
     option.  Any gain or loss on a subsequent  sale of the stock will be either
     long-term or short-term capital gain  or loss, depending on the  optionee's
     holding period for the stock disposed of.
 
          The  Corporation generally will be entitled to a deduction for Federal
     income tax purposes at the same time and in the same amount as the optionee
     is considered  to have  realized  ordinary income  in connection  with  the
     exercise  of the option. The deduction will be allowed for the taxable year
     of the Corporation  in which or  with which  ends the taxable  year of  the
     optionee in which such ordinary income is recognized.
 
          In addition, (i) any entitlement to a tax deduction on the part of the
     Corporation  is  subject to  the applicable  Federal tax  rules (including,
     without limitation, Code Section  162(m) regarding a $1,000,000  limitation
     on  deductible compensation), and (ii) in the event that the exercisability
     or vesting of any Plan Award is accelerated because of a change in control,
     payments relating to the Plan Awards  (or a portion thereof), either  alone
     or  together with certain other payments, may constitute parachute payments
     under Section 280G  of the  Code, which excess  amounts may  be subject  to
     excise taxes.
 
          SARs.   No  Federal  income  tax  consequences  are  incurred  by  the
     Corporation or the holder  at the time  an SAR is  granted pursuant to  the
     1992  Incentive Plan. However, upon the exercise of an SAR, the holder will
     realize ordinary income for Federal income tax purposes equal to the amount
     of cash or the value of property received by him. The Corporation generally
     will be  entitled  at such  time  to a  deduction  for Federal  income  tax
     purposes  in the same amount. If the holder of an SAR receives Common Stock
     upon the exercise of  such right, the holder's  basis in such Common  Stock
     will be its fair market value on the date of receipt and the holding period
     will  begin on such date.  Any gain or loss realized  upon the sale of such
     Common Stock will be either long-term  or short-term capital gain or  loss,
     depending on the optionee's holding period for the Common Stock.
 
          In addition, (i) any entitlement to a tax deduction on the part of the
     Corporation  is  subject to  the applicable  Federal tax  rules (including,
     without limitation, Code Section 162(m) regarding the $1,000,000 limitation
     on deductible compensation), and (ii) in the event that the  exercisability
     or vesting of any Plan Award is accelerated because of a change in control,
     payments  relating to the Plan Awards  (or a portion thereof), either alone
     or together with certain other payments, may constitute parachute  payments
     under  Section 280G  of the  Code, which excess  amounts may  be subject to
     excise taxes.
 
          Restricted Stock Awards. The Federal  income  tax  consequences  of  a
     restricted stock award  granted under  the 1986  Plan, the  1992  Incentive
     Plan, or  the  Directors'  Plan  will depend,  in  large  measure,  on  the
     restrictions placed on the stock.
 
          In  general,  if the  stock  is 'not  transferable'  and subject  to a
     'substantial risk  of forfeiture,'  as described  above, then,  unless  the
     recipient  makes an 83(b) election, he will recognize ordinary income equal
     to the fair market value of the stock on the first day the stock is  either
     transferable  or  not  subject to  a  substantial risk  of  forfeiture. The
     recipient's holding period will begin on  that day. If the recipient  makes
     an  83(b) election,  he will  recognize ordinary  income equal  to the fair
     market value of the stock at the  time of the award and his holding  period
     will  begin on that day.  The tax basis of the  stock will equal the amount
     included in income. Any gain or loss on a subsequent sale of the stock will
     be either long-term  or short-term capital  gain or loss  depending on  the
     recipient's holding period. The Corporation generally will be entitled to a
     deduction  equal  to  the  amount  of  ordinary  income  recognized  by the
     recipient.
 
                                       17
 
<PAGE>
<PAGE>
          In addition, (i) officers and directors of the Corporation subject  to
     Section  16(b)  liability may  be subject  to  special rules  regarding the
     income  tax  consequences  concerning  their  restricted  stock,  (ii)  any
     entitlement to a tax deduction on the part of the corporation is subject to
     the  applicable  Federal  tax rules  (including,  without  limitation, Code
     Section  162(m)   regarding  the   $1,000,000  limitation   on   deductible
     compensation), and (iii) in the event that the exercisability or vesting of
     any  Plan Award  is accelerated  because of  a change  in control, payments
     relating to  the  Plan Awards  (or  a  portion thereof),  either  alone  or
     together  with certain  other payments,  may constitute  parachute payments
     under Section 280G  of the  Code, which excess  amounts may  be subject  to
     excise  taxes.  Awards of  restricted stock  generally  do not  satisfy the
     exception for performance-based compensation under code Section 162(m).
 
     See page 12 of this Proxy Statement  for a discussion of Section 162(m)  of
the Code.
 
PROPOSED AMENDMENTS
 
     The  proposed amendments  to the 1992  Incentive Plan  affect the following
aspects of the 1992 Incentive Plan. The following is a summary and is  qualified
in  its entirety  by reference to  the 1992 Incentive  Plan, a copy  of which is
annexed as Exhibit A.
 
     Administration. The amendments provide that  the 1992 Incentive Plan  shall
henceforth  be administered by the  Committee as appointed from  time to time by
the Board of Directors  of the Corporation, which  committee shall be  comprised
solely  of two or more outside directors  as defined under Section 162(m) of the
Code and the Treasury Department regulations thereunder.
 
     Interpretation. The amendments  stipulate that the  1992 Incentive Plan  is
intended  to comply with the exception  for performance based compensation under
Section 162(m) of the  Code and the  Treasury Department regulations  thereunder
with  regard to  stock options and  stock appreciation rights  granted under the
1992 Incentive Plan and shall be limited, construed and interpreted in a  manner
so as to comply therewith.
 
     Individual  Limitations. The maximum number of shares of Common Stock which
may be subject to any stock option that may be granted to an eligible individual
(as determined pursuant to  Section 4 entitled  'Eligibility') shall not  exceed
250,000  shares of Common Stock (subject to any increase or decrease pursuant to
Section 10 (entitled  'Adjustments upon  Changes in  Capitalization')) for  each
calendar  year during the entire  term of the Plan.  The maximum number of stock
appreciation rights, whether granted alone or  in addition to other Plan  Awards
and  whether or not related  to a specific stock  option granted under the Plan,
that may be granted to an eligible individual (as determined pursuant to Section
4) shall not  exceed 250,000 (subject  to any increase  or decrease pursuant  to
Section  10) for each calendar  year during the entire term  of the Plan. To the
extent that shares of Common Stock for which stock options or stock appreciation
rights are permitted to be granted to an eligible individual pursuant to Section
3(b) (entitled 'Individual Limitations') during a calendar year are not  covered
by  a grant of an option or a stock appreciation right during the calendar year,
such shares of Common Stock shall not be available for grant of stock options or
stock appreciation rights, as applicable, in any subsequent calendar year during
the term of the Plan.
 
     Adjustments. The plan  is amended to  provide that the  Board of  Directors
shall  have the  right to  amend, suspend,  or terminate  the Plan  at any time;
provided, however, that no  such action shall  affect or in  any way impair  the
rights  of a recipient under any  Plan Award theretofore granted; and, provided,
further, that unless first duly approved by the stockholders of the  Corporation
entitled to vote thereon
 
                                       18
 
<PAGE>
<PAGE>
at  a meeting (which  may be the annual  meeting) duly called  and held for such
purpose, except as provided in Section 10,  or by a consent of stockholders,  no
amendment  or change shall be made in  the Plan: (a) increasing the total number
of shares which may be issued or  transferred under the Plan, including but  not
limited to the maximum limits for a calendar year under Section 3(b) with regard
to  both stock  options and  stock appreciation  rights (except  by operation of
Section 10);  (b) changing  the purchase  price hereinbefore  specified for  the
shares  subject  to  options;  (c)  changing  the  provisions  of  Section  8(a)
(concerning stock appreciation  rights); (d) extending  the period during  which
Plan Awards may be granted or exercised; (e) changing the designation of persons
eligible to receive Plan Awards; or (f) which would require stockholder approval
in  order for the Plan to continue  to comply with the exception for performance
based compensation under Section 162(m) with  regard to stock options and  stock
appreciation rights.
 
                                 PROPOSAL THREE
                              INDEPENDENT AUDITORS
 
     The  Board of  Directors has appointed  KPMG Peat  Marwick LLP, independent
certified public accountants, to audit the books and records of the  Corporation
for  the current  year, and  the Board recommends  that the  stockholders of the
Corporation confirm such appointment.
 
     Representatives of KPMG Peat Marwick LLP are expected to be present at  the
meeting  of stockholders and will be given an opportunity to make a statement if
they so desire.  They are  expected to be  available to  respond to  appropriate
questions.
 
                            STOCKHOLDERS' PROPOSALS
 
     Stockholders  of the Corporation wishing to  include proposals in the proxy
material in relation to the annual meeting of the Corporation to be held in 1997
must submit the same in writing so as to be received at the executive office  of
the Corporation on or before January 15, 1997. Such proposals must also meet the
other  requirements  of  the rules  of  the Securities  and  Exchange Commission
relating to stockholders' proposals.
 
                                          By Order of the Board of Directors,
                                          JOHN W. JACKSON
                                          Chairman of the Board and
                                          Chief Executive Officer
 
May 13, 1996
 
STOCKHOLDERS ARE REQUESTED TO DATE AND SIGN THE ENCLOSED PROXY AND RETURN IT  IN
THE  ENCLOSED, SELF-ADDRESSED ENVELOPE. NO POSTAGE  IS REQUIRED IF MAILED IN THE
UNITED STATES. YOUR PROMPT RESPONSE WILL  BE HELPFUL, AND YOUR COOPERATION  WILL
BE APPRECIATED.
 
                                       19
<PAGE>
<PAGE>
                                                                       EXHIBIT A
 
       (LANGUAGE WHICH IS CHANGED BY THE AMENDMENTS TO THE 1992 LONG-TERM
         INCENTIVE PLAN TO BE APPROVED BY STOCKHOLDERS IS IN ITALICS.)
 
                              CELGENE CORPORATION
                         1992 LONG-TERM INCENTIVE PLAN
 
1. PURPOSE
 
     The  purpose  of this  1992  Long-Term Incentive  Plan  (the 'Plan')  is to
encourage and enable selected management (excluding non-employee directors)  and
other  key  employees of  Celgene  Corporation (the  'Company')  or a  parent or
subsidiary of  the Company  to acquire  a proprietary  interest in  the  Company
through  the ownership of  common stock, par  value $.01 per  share (the 'Common
Stock'), of the Company.  Such ownership will provide  such persons with a  more
direct  stake in the future welfare of  the Company and encourage them to remain
with the Company or a parent or  subsidiary of the Company. It is also  expected
that  the Plan  will encourage qualified  persons to seek  and accept employment
with the Company or a parent or subsidiary of the Company. Pursuant to the Plan,
such persons  may  be granted  stock  options, restricted  stock  awards,  stock
appreciation   rights,   performance  awards,   and  other   stock-based  awards
(collectively, 'Plan Awards').
 
     As used herein, the term 'parent' or 'subsidiary' shall mean any present or
future corporation which is  or would be a  'parent corporation' or  'subsidiary
corporation'  of  the Company  as  the term  is defined  in  Section 424  of the
Internal Revenue Code  of 1986, as  amended (the 'Code')  (determined as if  the
Company were the employer corporation).
 
2. ADMINISTRATION OF THE PLAN
 
     The Plan shall be administered by a Management Compensation and Development
Committee  (the 'Committee')  as appointed  from time  to time  by the  Board of
Directors of the Company,  which committee shall be  comprised solely of two  or
more  outside directors  as defined  under Section  162(m) of  the Code  and the
Treasury regulations thereunder. No  person while a member  of the Committee  or
any  other committee of the  Board of Directors administering  the Plan shall be
eligible to receive a Plan Award or shall have received a Plan Award during  the
one-year  period preceding the  commencement of his service  on the Committee or
any other such committee.
 
     In  administering  the  Plan,  the  Committee  shall  follow  any   general
guidelines  not inconsistent with the Plan established by the Board of Directors
and  may  adopt  rules   and  regulations  for  carrying   out  the  Plan.   The
interpretation  and decision made  by the Committee with  regard to any question
arising  under  the  Plan  shall  be   final  and  conclusive  on  all   persons
participating  or eligible to participate in the Plan. Subject to the provisions
of the  Plan and  any guidelines  established  by the  Board of  Directors,  the
Committee from time to time shall determine the terms and conditions of all Plan
Awards,  including, but  not limited to,  the persons  to whom, and  the time or
times at which, Plan Awards  shall be granted, the  number of shares subject  to
each Plan Award, the number of options which shall be treated as incentive stock
options  (as described in Section 422 of the Code), the duration of each option,
the specific restrictions applicable to  restricted stock awards and other  Plan
Awards, and other terms and provisions of each Plan Award. This Plan is intended
to  comply with the  exception for performance  based compensation under Section
162(m) of the Code and the Treasury regulations thereunder with regard to  stock
options  and stock appreciation  rights granted hereunder  and shall be limited,
construed and interpreted in a manner so as to comply therewith.
 
3. SHARES OF STOCK SUBJECT TO THE PLAN
 
(A) GENERAL LIMITATION
 
     Except as provided in Section 10,  the aggregate number of shares that  may
be  issued or  transferred pursuant  to Plan  Awards shall  not exceed 1,000,000
shares of Common Stock. Such shares of Common Stock available under the Plan may
be   authorized   and    unissued   shares   or    previously   issued    shares
 
                                      A-1
 
<PAGE>
<PAGE>
acquired  or to  be acquired  by the  Company and  held in  treasury. Any shares
subject to  a  Plan  Award which  for  any  reason terminates,  expires,  or  is
forfeited  without the delivery to the holder  of the Plan Award of Common Stock
or other consideration may  again be subject  to a new  Plan Award, except  that
shares  subject to a restricted stock award  that are forfeited after the holder
thereof has received dividends or other benefits of ownership (excluding  voting
rights)  shall not thereafter be available for grant pursuant to the Plan. If an
option or related stock  appreciation right is exercised  for stock, the  shares
covered  by such option shall not thereafter  be available for grant pursuant to
the Plan. Any shares  of Common Stock that  are used by a  recipient as full  or
partial payment of withholding or other taxes or of the purchase price of shares
of  Common Stock acquired on  the exercise of an  option shall not thereafter be
available for Plan Awards.
 
(B) INDIVIDUAL LIMITATIONS.
 
     The maximum number of shares  of Common Stock which  may be subject to  any
stock  option  that may  be  granted to  an  eligible individual  (as determined
pursuant to Section 4  herein) shall not exceed  250,000 shares of Common  Stock
(subject  to any increase or decrease pursuant  to Section 10) for each calendar
year  during  the  entire  term  of  the  Plan.  The  maximum  number  of  stock
appreciation  rights, whether granted alone or  in addition to other Plan Awards
and whether or not related  to a specific stock  option granted under the  Plan,
that may be granted to an eligible individual (as determined pursuant to Section
4 herein) shall not exceed 250,000 (subject to any increase or decrease pursuant
to Section 10) for each calendar year during the entire term of the Plan. To the
extent that shares of Common Stock for which stock options or stock appreciation
rights  are permitted to be  granted to an eligible  individual pursuant to this
Section 3(b) during a calendar year are not covered by a grant of an option or a
stock appreciation right during the calendar  year, such shares of Common  Stock
shall  not be available for grant of stock options or stock appreciation rights,
as applicable, in any subsequent calendar year during the term of the Plan.
 
4. ELIGIBILITY
 
     Plan Awards may be granted to management (excluding non-employee directors)
and other  key  employees  who are  employed  by  the Company  or  a  parent  or
subsidiary of the Company.
 
5. GRANTING OF PLAN AWARDS
 
     All Plan Awards shall be granted within 10 years from March 13, 1992.
 
6. OPTIONS
 
     Options  shall be  evidenced by stock  option agreements in  such form, not
inconsistent with the Plan,  as the Committee shall  approve from time to  time,
which  agreements need not be  identical, and shall be  subject to the following
terms and conditions and  such other terms and  conditions as the Committee  may
prescribe:
 
          (a)  Option Price. The purchase price under each stock option shall be
     not less than 100% of the fair market value of the Common Stock at the time
     the option is granted and not less than the par value of such Common Stock.
     In the case of an incentive stock option granted to an employee owning more
     than 10% of the total combined voting power of all classes of stock of  the
     Company   or  of  any   parent  or  subsidiary  of   the  Company  (a  '10%
     Stockholder'), actually or constructively under Section 424(d) of the Code,
     the option price shall not  be less than 110% of  the fair market value  of
     the  Common Stock subject to the option at  the time of its grant. The fair
     market value of the  Common Stock on  any date shall  be determined by  the
     Committee in a manner consistent with the requirements of the Code.
 
          (b)  Medium  and  Time of  Payment.  Stock purchased  pursuant  to the
     exercise of an option shall at the time of purchase be paid for in full  in
     cash,  or with shares of Common Stock,  or a combination of cash and Common
     Stock to be valued  at the fair  market value thereof on  the date of  such
     exercise;  provided, however, that any shares  of Common Stock so delivered
     shall have been beneficially owned by the optionee for a period of not less
     than six months prior to the date of
 
                                      A-2
 
<PAGE>
<PAGE>
     exercise. Upon receipt of payment and such documentation as the Company may
     deem necessary to establish compliance with the Securities Act of 1933, the
     Company shall, without stock transfer tax  to the optionee or other  person
     entitled  to  exercise the  option, deliver  to  the person  exercising the
     option a  certificate  or certificates  for  such  shares. It  shall  be  a
     condition  to  the  performance of  the  Company's obligation  to  issue or
     transfer Common  Stock upon  exercise  of an  option  or options  that  the
     optionee pay, or make provision satisfactory to the Company for the payment
     of,  any  taxes (other  than  stock transfer  taxes)  which the  Company is
     obligated to collect with respect to the issue or transfer of Common  Stock
     upon  such  exercise, including  any Federal,  state, or  local withholding
     taxes. At the discretion of the Committee,  such taxes may be paid in  cash
     or  by tender  of the option  holder or  withholding by the  Company of the
     number of shares of Common Stock whose fair market value equals the  amount
     required to be withheld. At the discretion of the Committee, such taxes may
     be paid by the Company.
 
          (c)  Waiting Period.  The waiting  period and  time for  exercising an
     option shall  be  prescribed by  the  Committee in  each  particular  case;
     provided,  however, that  no stock option  may be exercised  after 10 years
     from the date  it is  granted. In  the case  of an  incentive stock  option
     granted  to  a  10%  Stockholder,  such  option,  by  its  terms,  shall be
     exercisable only within five years from the date of grant.
 
          (d) Reload Options. The Committee shall have the authority (but not an
     obligation) to include  within any option  agreement a provision  entitling
     the  optionee  to a  further  option (a  'Reload  Option') if  the optionee
     exercises the option  evidenced by  the option  agreement, in  whole or  in
     part,  by surrendering other shares of the Company held by the optionee for
     at least six months prior to such date of surrender in accordance with  the
     Plan  and the terms and conditions of the option agreement. Any such Reload
     Option shall not be  an incentive stock  option, shall be  for a number  of
     shares  equal  to  the number  of  surrendered shares,  the  exercise price
     thereof shall be equal to the fair market value of the Common Stock on  the
     date  of exercise of such original  option, shall become exercisable if the
     purchased shares are held for a  minimum period of time established by  the
     Committee,  and shall be subject to such  other terms and conditions as the
     Committee may determine.
 
7. RESTRICTED STOCK AWARDS
 
     Restricted stock awards shall be evidenced by agreements in such form,  not
inconsistent  with the Plan, as  the Committee shall approve  from time to time,
which agreements need not  be identical, and shall  be subject to the  following
terms  and conditions and such  other terms and conditions  as the Committee may
prescribe:
 
          (a) Forfeiture Period. The period  and time during and the  conditions
     and  restrictions  under  which  a restricted  stock  award  is  subject to
     forfeiture (the 'Restriction Period') shall be prescribed by the  Committee
     in each particular case, subject to the provisions of Section 15.
 
          (b)  Restrictive Legend  and Stock Power.  Each certificate evidencing
     shares of Common Stock  subject to a restricted  stock award shall bear  an
     appropriate  legend referring  to the  terms, conditions,  and restrictions
     applicable to such restricted stock award. The Committee may prescribe that
     the certificates evidencing  such shares  be held in  escrow by  a bank  or
     other  institution,  or that  the Company  may itself  hold such  shares in
     escrow, until the restrictions thereon  shall have lapsed and may  require,
     as a condition of any restricted stock award, that the recipient shall have
     delivered  a stock power endorsed in blank relating to the shares of Common
     Stock subject to the  restricted stock award. Upon  the termination of  the
     Restriction  Period with respect to any shares of Common Stock subject to a
     restricted stock  award, the  certificate evidencing  such shares  will  be
     delivered  out of  escrow subject to  the satisfaction by  the recipient of
     applicable  Federal  and   state  securities  laws   and  withholding   tax
     requirements,  including any Federal, state, or local withholding taxes. At
     the discretion of  the Committee,  such taxes  may be  paid in  cash or  by
     tender  of the holder of restricted stock  or withholding by the Company of
     the number of  shares of Common  Stock whose fair  market value equals  the
     amount  required to be  withheld. At the discretion  of the Committee, such
     taxes may be paid by the Company.
 
                                      A-3
 
<PAGE>
<PAGE>
8. STOCK APPRECIATION RIGHTS
 
     (a) A stock appreciation right means  a right granted pursuant to the  Plan
to  receive, upon the  exercise of such right  up to the excess  of (i) the fair
market value of one share of Common Stock on the date of exercise or at any time
during a specified period before the date of exercise, over (ii) the fair market
value of one  share of Common  Stock on the  date of grant.  Any payment by  the
Company  in respect of such  right may be made in  cash, shares of Common Stock,
other property,  or any  combination  thereof, as  the  Committee, in  its  sole
discretion, shall determine.
 
     (b) Stock appreciation rights may be granted either alone or in addition to
other  Plan Awards  granted under the  Plan and may,  but need not,  relate to a
specific  stock  option  granted  under  the  Plan.  The  provisions  of   stock
appreciation  rights need not be the same  with respect to each participant. Any
stock appreciation right related to  a stock option may  be granted at the  same
time  such stock option is granted or  at any time thereafter before exercise or
expiration of such  stock option. In  the case of  any stock appreciation  right
related  to any stock option, the stock appreciation right or applicable portion
thereof shall terminate  and no longer  be exercisable upon  the termination  or
exercise  of the  related stock option,  except that a  stock appreciation right
granted with respect  to less than  the full  number of shares  of Common  Stock
covered  by a related  stock option shall  only be reduced  when the exercise or
termination of the related stock option exceeds the number of shares not covered
by the  stock  appreciation  right.  Any  stock  option  related  to  any  stock
appreciation  right shall  no longer  be exercisable  to the  extent the related
stock appreciation right has been exercised. Unless otherwise determined by  the
Committee,  the exercise date may not be  earlier than six months after the date
of grant and  shall be  limited to  the period of  time beginning  on the  third
business  day following  the date  of release  for publication  of the Company's
quarterly or annual  summary statements of  earnings and ending  on the  twelfth
business day following such release.
 
9. PERFORMANCE AWARDS; OTHER STOCK-BASED AWARDS
 
     (a)  Performance awards may  be granted under  the Plan and  may consist of
stock  options,  restricted  stock  awards,  stock  appreciation  rights,  other
stock-based  awards, cash, or other property.  The Committee shall prescribe the
terms and conditions  of such  awards, including  determining the  type of  Plan
Award  to  be granted,  the recipient  thereof, the  performance goals  for each
recipient, the time periods within which each performance goal must be attained,
the determination date of the attainment of  each goal, and the extent to  which
each  goal has been attained.  The provisions of performance  awards need not be
the same with respect to each participant.
 
     (b) The Committee is authorized to  grant such other awards denominated  or
payable in, valued in whole or in part by reference to, or otherwise based on or
related  to,  Common Stock  (including, without  limitation, phantom  shares and
securities convertible  into shares  of  Common Stock),  as  are deemed  by  the
Committee  to be consistent  with the purposes  of the Plan,  provided that such
grants shall comply with applicable law. Subject  to the terms of the Plan,  the
Committee  shall determine  the terms and  conditions of such  awards. Shares of
Common Stock or other securities delivered pursuant to a purchase, exchange,  or
conversion  right  granted under  this  Section 9(b)  shall  be issued  for such
consideration, which may be paid by such  method or methods and in such form  or
forms,  including,  without  limitation,  cash,  shares  of  Common  Stock other
securities, other Plan Awards, or other property, or any combination thereof, as
the Committee shall determine. Agreements  relating to other stock-based  awards
shall  contain provisions dealing with the disposition of such Plan Award in the
event  of  termination  of  the  participant's  employment  prior  to  exercise,
realization,  or payment of such Plan Award. The provisions of other stock-based
awards need not be the same with respect to each participant.
 
10. ADJUSTMENTS UPON CHANGES IN CAPITALIZATION
 
     If dividends payable in Common Stock during any fiscal year of the  Company
exceed  in the aggregate  5% of the  Common Stock issued  and outstanding at the
beginning of such  fiscal year, or  if there is  during any fiscal  year of  the
Company  one or more  splits, subdivisions, or combinations  of shares of Common
stock resulting  in an  increase  or decrease  by more  than  5% of  the  shares
outstanding
 
                                      A-4
 
<PAGE>
<PAGE>
at  the beginning  of the year,  the number  of shares available  under the Plan
shall be increased or decreased proportionately, as the case may be, the  number
of shares subject to stock appreciation rights and the related fair market value
thereof as of the date of grant shall be increased or decreased proportionately,
as  the case  may be,  and the  number of  shares deliverable  upon the exercise
thereafter of any options  theretofore granted shall  be increased or  decreased
proportionately,  as the case  may be, without change  in the aggregate purchase
price. Common Stock dividends, splits, subdivisions, or combinations during  any
fiscal  year which do not exceed in the  aggregate 5% of the Common Stock issued
and outstanding at the beginning of such  year shall be ignored for purposes  of
the  Plan. All adjustments shall be made as of the day such action necessitating
such adjustment becomes effective.
 
     In case the Company is merged or consolidated with another corporation,  or
in case the property or stock of the Company is acquired by another corporation,
or  in case  of a  reorganization or  liquidation of  the Company,  the Board of
Directors of the Company, or the board of directors of any corporation  assuming
the  obligations of  the Company  hereunder, shall  either (i)  make appropriate
provisions for  the protection  of any  Plan Awards  by the  substitution on  an
equitable  basis  of appropriate  stock  or other  property  of the  Company, or
appropriate stock or other  property of the  merged, consolidated, or  otherwise
reorganized  corporation,  provided only  that such  substitution of  options or
other property shall comply with the requirements of Section 424 of the Code, or
(ii) terminate all  restrictions relating  to restricted stock  awards and  give
written  notice to optionees that their options and any stock appreciation right
or other Plan Award, which  will become immediately exercisable  notwithstanding
any  waiting period or other restriction  otherwise prescribed by the Committee,
must be exercised  within 30 days  of the date  of such notice  or they will  be
terminated.
 
11. TERMINATION AND AMENDMENT OF THE PLAN
 
     The Board of Directors shall have the right to amend, suspend, or terminate
the  Plan at any time; provided, however, that no such action shall affect or in
any way  impair the  rights of  a  recipient under  any Plan  Award  theretofore
granted;  and,  provided,  further,  that  unless  first  duly  approved  by the
stockholders of the Company entitled to vote thereon at a meeting (which may  be
the annual meeting) duly called and held for such purpose, except as provided in
Section  10, or by  a consent of  stockholders, no amendment  or change shall be
made in the Plan: (a) increasing the total number of shares which may be  issued
or  transferred under the Plan, including but  not limited to the maximum limits
for a calendar year  under Section 3(b)  with regard to  both stock options  and
stock  appreciation rights (except by operation of Section 10); (b) changing the
purchase price hereinbefore  specified for  the shares subject  to options;  (c)
changing  the provisions of Section 8(a);  (d) extending the period during which
Plan Awards may be granted or exercised; (e) changing the designation of persons
eligible to receive Plan Awards; or (f) which would require stockholder approval
in order for the Plan to continue  to comply with the exception for  performance
based  compensation under Section 162(m) with  regard to stock options and stock
appreciation rights.
 
12. ADDITIONAL RESTRICTIONS RELATING TO INCENTIVE STOCK OPTIONS
 
     Without the  written  consent of  the  Company,  no stock  acquired  by  an
optionee  upon exercise  of an incentive  stock option granted  hereunder may be
disposed of by the optionee within two years from the date such incentive  stock
option  was granted, nor within one year after the transfer of such stock to the
optionee; provided, however, that  a transfer to a  trustee, receiver, or  other
fiduciary in any insolvency proceeding, as described in Section 422(c)(3) of the
Code,  shall not be deemed to be such  a disposition. If Section 422 of the Code
is amended  during the  term of  the Plan,  the Committee  may modify  the  Plan
consistently with such amendment.
 
13. TERMINATION DATE OF THE PLAN
 
     The Plan shall become effective March 13, 1992, the date of its adoption by
the  favorable vote of  the majority of  the Board of  Directors of the Company,
subject, however,  to approval  by the  stockholders of  the Company  within  12
months  next following  such adoption  by the  Board of  Directors; and  if such
approval is not obtained, the  Plan and any and  all Plan Awards granted  during
such interim
 
                                      A-5
 
<PAGE>
<PAGE>
period  shall terminate and be of no further force or effect. The Plan shall, in
all events, terminate on March 12, 2002, or on such earlier date as the Board of
Directors of the Company may determine.  Any option or stock appreciation  right
outstanding at the termination date shall remain outstanding until it has either
expired  or has  been exercised. Any  restricted stock award  outstanding at the
termination  date  shall  remain  subject  to  the  terms  of  Plan  until   the
restrictions   thereon  shall  have  lapsed.  Any  performance  award  or  other
stock-based award outstanding at  the termination date  shall remain subject  to
the terms of the Plan and such award.
 
14. DEATH, RETIREMENT, AND TERMINATION OF EMPLOYMENT
 
     (a)  An  employee's  option  or  stock  appreciation  right  which  has not
theretofore expired, shall terminate 30 days  after the date of the  termination
for  any reason, other than for cause  (as defined in Section 15(a)(ii)), death,
or Retirement (as hereinafter  defined), of the  employee's employment with  the
Company  or a parent or subsidiary of the Company, subject to the condition that
no option or stock appreciation right  granted in connection with an option  may
be exercised in whole or in part after the expiration date of the option or more
than  10 years  after the  date of  grant of  such option  or stock appreciation
right.
 
     (b) With respect  to non-qualified options  and stock appreciation  rights,
upon  the termination of the employment of any employee due to retirement at age
60 or older or disability (as hereinafter defined) (collectively, 'Retirement'),
the employee may, during a period (the 'Retirement Period') which is the  longer
of  (i)  up  to 10  years  after  the date  of  grant  of such  option  or stock
appreciation right,  such period  to be  set  on a  case by  case basis  by  the
Committee,  or (ii) three years from the date of such termination, exercise such
stock appreciation right or purchase  some or all of  the shares covered by  the
employee's  non-qualified  stock option  which  was exercisable  under  the Plan
immediately prior to such termination.
 
     (c) With respect to  incentive stock options, upon  the termination of  the
employment  of any  such employee  due to  Retirement, the  employee may, within
three months  after the  date of  such termination  (12 months  in the  case  of
disability),  purchase some or all  of the shares covered  by an incentive stock
option  which  was  exercisable  under  the  Plan  immediately  prior  to   such
termination;  shares not purchased within three months (12 months in the case of
disability) after the date of termination due to Retirement under such incentive
stock option may be purchased during  the Retirement Period, but no longer  will
be  incentive stock option  stock and will be  non-qualified stock option stock;
prior to such purchase, the option will remain subject to the provisions of  the
Plan governing incentive stock options.
 
     (d)  Upon the death of any employee while  in active service or of any such
disabled or retired employee within the above-referenced periods, the person  or
persons  to whom  the employee's  rights under  an option  or stock appreciation
right are  transferred by  will or  the laws  of descent  and distribution  may,
within  12 months after  the date of  the employee's death,  exercise such stock
appreciation right or purchase some or all  of the shares to which the  employee
was  entitled pursuant to the exercise of an  option under the Plan, on the date
of his death.
 
     (e) Leaves  of  absence pursuant  to  Section  16(d) shall  not  be  deemed
terminations  or interruptions of  employment. For purposes  of this Section 14,
'disability' shall have the meaning provided in Section 22(e)(3) of the Code.
 
     (f) If a recipient of a performance award ceases to be an employee for  any
reason  prior to the date that a determination with respect to the attainment of
his performance goal would otherwise be made, such former employee's performance
award shall terminate and no  shares shall be issuable  and no amounts shall  be
payable  at any time, unless the Committee otherwise determines to issue some or
all of the shares subject to such award or  to pay some or all of such award  to
such former employee or his legal representative.
 
15. ACCELERATION OF VESTING
 
     (a) Following a Change in Control (as defined in Section 15(c)), an option,
stock  appreciation right,  restricted stock  award, or  other Plan  Award shall
automatically be vested and immediately exercisable in full and any restrictions
contained in any restricted stock  award shall automatically terminate upon  the
occurrence of either of the following events:
 
                                      A-6
 
<PAGE>
<PAGE>
          (i)  change  in an  employee's title  or a  significant change  in the
     nature or scope of the  authorities, powers, functions, or duties  normally
     attached  to such  employee's position with  the Company  within a two-year
     period after a Change in Control, and such person terminates his employment
     with the Company within 90 days after such change in title or duties; or
 
          (ii) termination of the recipient's employment by the Company  without
     cause  within a two-year period after a  Change in Control. For purposes of
     Section 14(a) and  this Section 15(a)(ii),  'cause' is defined  as (a)  the
     conviction  by the holder of a Plan Award  of a felony or a crime involving
     moral turpitude or (b) the  commission by the holder of  a Plan Award of  a
     public  or notorious act  which subjects the  Company to public disrespect,
     scandal, or ridicule and which adversely affects the value of the  services
     to the Company of the holder of the Plan Award.
 
     In  either of such events, notwithstanding  the provisions of Section 14, a
Plan Award holder  may, within three  years after the  date of such  termination
(but  not more than 10 years after the date of grant), exercise such Plan Award;
provided, however, that upon the death of any such Plan Award holder within this
three-year period, the person or persons to whom the Plan Award holder's  rights
are  transferred by will or the laws  of descent and distribution may, within 12
months after the date  of the Plan  Award holder's death (but  not more than  10
years  after the date of grant), exercise such Plan Award to the extent that the
Plan Award holder was entitled  to exercise such Plan Award  on the date of  his
death.
 
     (b) The Committee shall have the authority at any time or from time to time
accelerate  the  vesting of  any Plan  Award and  to permit  any Plan  Award not
theretofore exercisable  to become  immediately exercisable  and to  permit  the
immediate  termination  of any  restrictions contained  in any  restricted stock
award or other Plan Award.
 
     (c) For purposes hereof, a change in control (a 'Change in Control')  shall
be deemed to occur:
 
          (i)  if any person within  the meaning of Sections  13(d) and 14(d) of
     the Securities Exchange Act of 1934, other  than the Company or any of  its
     subsidiaries,  has become the beneficial owner,  within the meaning of Rule
     13d-3 under the Securities Exchange Act of  1934, of 30 percent or more  of
     the  combined  voting  power  of  the  Company's  then  outstanding  voting
     securities; or
 
          (ii) when a majority of the directors elected at any special or annual
     meeting of  stockholders are  not individuals  nominated by  the  Company's
     incumbent  Board of  Directors or when  individuals who are  members of the
     Company's Board of Directors at  any one time shall immediately  thereafter
     cease to constitute a majority of the Board of Directors.
 
16. MISCELLANEOUS PROVISIONS
 
     (a)  Rights as an Employee. Nothing in the  Plan, the grant or holding of a
Plan Award, or in any agreement entered  into pursuant to the Plan shall  confer
to  holders of Plan Awards any right to continue in the employ of the Company or
any parent or subsidiary of the Company  or interfere in any way with the  right
of  the Company  or any  parent or  subsidiary of  the Company  to terminate the
employment of a recipient at any time.
 
     (b) Rights  as  a Stockholder.  Except  as  provided in  Section  16(c),  a
recipient a restricted stock award shall have all of the rights of a stockholder
with  respect to  all of the  shares of  Common Stock subject  to the restricted
stock award, including, without limitation, the right to vote such shares and to
receive dividends in cash or other property or other distributions or rights  in
respect  of such shares.  A recipient of  a Plan Award  (other than a restricted
stock award) shall have no  rights as a stockholder  with respect to any  shares
issuable   or  transferable  upon  exercise  thereof  until  the  date  a  stock
certificate is issued to him for such shares, and, except as otherwise expressly
provided in the Plan, no adjustment shall be made for dividends or other  rights
for which the record date is prior to the date such stock certificate is issued.
 
     (c)  Non-Assignability of Plan Awards. No Plan Award shall be assignable or
transferable by the  recipient, except by  will or  by the laws  of descent  and
distribution,  provided that such restriction on the transfer or assignment of a
restricted stock award shall expire upon  the date of expiration of the  related
Restriction  Period. During  the lifetime of  a recipient, Plan  Awards shall be
exercisable only by him or
 
                                      A-7
 
<PAGE>
<PAGE>
his personal representative or guardian. No  Plan Award or interest therein  may
be  pledged,  attached,  or otherwise  encumbered  other  than in  favor  of the
Company.
 
     (d) Leave of  Absence. In  the case  of a  holder of  a Plan  Award on  all
approved  leave of absence,  the Committee may,  if it determines  that to do so
would be in the best  interests of the Company, provide  in a specific case  for
continuation  of Plan Awards during such  leave of absence, such continuation to
be on such terms and conditions  as the Committee determines to be  appropriate,
except  that  in  no  event  shall an  option  or  stock  appreciation  right be
exercisable after 10 years from the date it is granted.
 
     (e) Other Restrictions. Each Plan Award shall be subject to the requirement
that, if at any time the Board of Directors or the Committee shall determine, in
its discretion, that the listing,  registration, or qualification of the  shares
issuable  or transferable upon exercise thereof  upon any securities exchange or
under any state or Federal law, or  the consent or approval of any  governmental
regulatory  body is necessary or  desirable as a condition  of, or in connection
with, the granting of  such Plan Award  or the issue,  transfer, or purchase  of
shares  thereunder, such  Plan Award may  not be  exercised in whole  or in part
unless such  listing, registration,  qualification, consent,  or approval  shall
have  been effected  or obtained  free of any  conditions not  acceptable to the
Board of Directors.  The Company shall  not be  obligated to sell  or issue  any
shares  of Common Stock in any manner  in contravention of the Securities Act of
1933 or any state securities law.
 
                                      A-8

<PAGE>
<PAGE>

                           APPENDIX 1 -- PROXY CARD

                              CELGENE CORPORATION

                                     PROXY

     The undersigned hereby appoints John W. Jackson and Sol J. Barer,  and each
of them, with power of substitution, to  represent  and to vote on behalf of the
undersigned all of the shares of Celgene Corporation (the "Corporation")  which
the  undersigned is entitled to vote at the Annual Meeting of Stockholders to be
held at the offices of Proskauer Rose Goetz & Mendelsohn  LLP, 26th floor,  1585
Broadway, New York, New York 10036 on Friday, June 14, 1996, at 1:00 p.m., local
time,  and at any  adjournment  or  adjournments  thereof,  hereby  revoking all
proxies  heretofore  given  with  respect  to such  stock,  upon  the  following
proposals  more fully  described  in the notice of and proxy  statement  for the
meeting (receipt of which is hereby acknowledged).

                       (To be Signed on Reverse Side)

                                                           See Reverse Side

<PAGE>
<PAGE>

[X]  Please mark your
     votes as in this
     example.

THE BOARD OF DIRECTORS RECOMMENDS A VOTE FOR (1), (2), and (3).

1. ELECTION OF DIRECTORS

   FOR all nominees listed below (except as marked to the contrary) [ ]

   WITHHOLD AUTHORITY to vote for all nominees listed below [ ]

   Nominees: John W. Jackson, Sol J. Barer, Frank T. Cary,
             Richard C. E. Morgan, Walter L. Robb, Lee J. Schroeder,
             Arthur Hull Hayes, Jr.

   (INSTRUCTION: To withhold authority to vote for any individual nominee, write
   that nominee's name on the space provided below.)

   _____________________________________________________________________________

2. PROPOSAL TO APPROVE THE AMENDMENT TO THE 1992 LONG-TERM INCENTIVE PLAN.

         [ ] FOR    [ ] AGAINST    [ ] ABSTAIN

3. PROPOSAL TO APPROVE THE APPOINTMENT OF KPMG PEAT MARWICK LLP AS THE
   INDEPENDENT CERTIFIED PUBLIC ACCOUNTANTS OF THE CORPORATION.

         [ ] FOR    [ ] AGAINST    [ ] ABSTAIN

4. In  their discretion upon such other matters as may properly come before the
   meeting.

          I will attend the meeting.[ ]     I will not attend the meeting. [ ]

          THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS.

THIS PROXY, WHEN PROPERLY EXECUTED,  WILL BE VOTED IN THE MANNER DIRECTED HEREIN
BY THE  UNDERSIGNED  STOCKHOLDER.  IF NO DIRECTION  IS MADE,  THIS PROXY WILL BE
VOTED FOR PROPOSALS 1, 2, AND 3.



_____________________________________    Date ________________________
             Signature



_____________________________________    Date _________________________
    Signature if held jointly

Please sign exactly as name appears hereon.  Joint owners should each sign. When
signing as attorney, executor, administrator,  trustee, or guardian, please give
full title as such.  If a  corporation,  please sign in full  corporate  name by
President  or  other  authorized  officer.  If a  partnership,  please  sign  in
partnership name by authorized person.

         Please return promptly in the enclosed postage-paid envelope.

<PAGE>



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