CELGENE CORP /DE/
S-3/A, 1996-05-30
INDUSTRIAL ORGANIC CHEMICALS
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     As filed with the Securities and Exchange Commission on May 30, 1996
                                                      Registration No. 333-2517
                                                                           
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                               ------------------
                                 AMENDMENT NO. 1
                                       TO
                                    FORM S-3
    
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933
                               ------------------
                               CELGENE CORPORATION
             (Exact name of Registrant as specified in its charter)
                               ------------------
            DELAWARE                        8731                 22-2711928
(State or other jurisdiction of (Primary Standard Industrial  (I.R.S. Employer
 incorporation or organization)  Classification Code Number) Identification No.)

                  7 POWDER HORN DRIVE, WARREN, NEW JERSEY 07059
                                 (908) 271-1001
          (Address, including zip code, and telephone number, including
             area code, of Registrant's principal executive offices)
                               ------------------
                                 JOHN W. JACKSON
                CHAIRMAN OF THE BOARD AND CHIEF EXECUTIVE OFFICER
                               CELGENE CORPORATION
                               7 POWDER HORN DRIVE
                            WARREN, NEW JERSEY 07059
                                 (908) 271-1001
            (Name, address, including zip code, and telephone number,
                   including area code, of agent for service)

                          Copies of Communications to:
                             Arnold S. Jacobs, Esq.
                      Proskauer Rose Goetz & Mendelsohn LLP
                                  1585 Broadway
                               New York, New York 10036
                                 (212) 969-3000
                               ------------------

        APPROXIMATE DATE OF COMMENCEMENT OF PROPOSED SALE TO THE PUBLIC: As soon
as practicable after this Registration Statement becomes effective.

        If the only securities  being  registered on this Form are being offered
pursuant to dividend or interest  investment  plans,  please check the following
box. [ ]

        If any of the securities being registered on this Form are to be offered
on a delayed or continuous  basis  pursuant to Rule 415 under the Securities Act
of 1933 check the following box. [X]

        If this Form is filed to register additional  securities for an offering
pursuant to Rule 462(b) under the Securities Act, please check the following box
and list  the  Securities  Act  registration  statement  number  of the  earlier
effective registration statement for the same offering. [ ] _______________

        If this Form is a post-effective amendment filed pursuant to Rule 462(c)
under the  Securities  Act,  check the following box and list the Securities Act
registration  statement number of the earlier effective  registration  statement
for the same offering. [ ] _______________

     If delivery of the  prospectus is expected to be made pursuant to Rule 434,
please check the following box. [ ]

        The Registrant hereby amends this registration statement on such date or
dates as may be necessary to delay its effective date until the Registrant shall
file a further  amendment  which  specifically  states  that  this  Registration
Statement shall  thereafter  become effective in accordance with Section 8(a) of
the  Securities  Act of 1933 or until the  Registration  Statement  shall become
effective on such date as the Commission,  acting pursuant to said section 8(a),
may determine.

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                               CELGENE CORPORATION

                                3,137,825 SHARES

                                  COMMON STOCK
                           (PAR VALUE $0.01 PER SHARE)


This Prospectus relates to the public offering, which is not being underwritten,
of up to 3,137,825  shares (the  "Securities")  of Common Stock, par value $0.01
per share (the "Common Stock") of Celgene Corporation (the "Company").

All of the 3,137,825 shares of Common Stock may be sold by certain  stockholders
of the  Company or by  pledgees,  donees,  transferees  or other  successors  in
interest that receive such shares as a gift,  partnership  distribution or other
non-sale related transfer (the "Selling  Stockholders").  The sale of the shares
by the Selling  Stockholders  may be effected from time to time in  transactions
(which may  include  block  transactions  by or for the  account of the  Selling
Stockholders)  in the  over-the-counter  market or in  negotiated  transactions,
through the writing of options on such shares,  short sales,  a  combination  of
such methods of sale, or otherwise.  Sales may be made at fixed prices which may
be changed,  at market  prices  prevailing at the time of sale, or at negotiated
prices. The Company will not receive any proceeds from the sale of shares by the
Selling Stockholders. See "Selling Stockholders" and "Plan of Distribution."

SEE "RISK FACTORS"  STARTING ON PAGE 4 FOR A DISCUSSION OF CERTAIN FACTORS TO BE
CONSIDERED BY PROSPECTIVE INVESTORS.

THESE  SECURITIES  HAVE NOT BEEN APPROVED OR  DISAPPROVED  BY THE SECURITIES AND
EXCHANGE  COMMISSION OR ANY STATE  SECURITIES  COMMISSION NOR HAS THE SECURITIES
AND  EXCHANGE  COMMISSION  OR ANY STATE  SECURITIES  COMMISSION  PASSED UPON THE
ACCURACY OR ADEQUACY OF THIS PROSPECTUS. ANY REPRESENTATION TO THE CONTRARY IS A
CRIMINAL OFFENSE.

NO DEALER,  SALESPERSON  OR OTHER  INDIVIDUAL  HAS BEEN  AUTHORIZED  TO GIVE ANY
INFORMATION OR MAKE ANY  REPRESENTATIONS  IN CONNECTION WITH THIS OFFERING OTHER
THAN THOSE CONTAINED IN THIS PROSPECTUS AND, IF GIVEN OR MADE, SUCH  INFORMATION
OR  REPRESENTATIONS  MUST NOT BE RELIED  UPON AS HAVING BEEN  AUTHORIZED  BY THE
COMPANY. THIS PROSPECTUS DOES NOT CONSTITUTE AN OFFER TO SELL, OR A SOLICITATION
OF AN OFFER TO BUY ANY OF THE SECURITIES IN ANY  JURISDICTION  WHERE,  OR TO ANY
PERSON TO WHOM, IT IS UNLAWFUL TO MAKE SUCH OFFER OR SOLICITATION.  THE DELIVERY
OF THIS PROSPECTUS AT ANY TIME DOES NOT IMPLY THAT INFORMATION HEREIN IS CORRECT
AS OF ANY TIME SUBSEQUENT TO ITS DATE.

   

                 The date of this Prospectus is May 30, 1996.
    


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                              AVAILABLE INFORMATION

        The  Company  is  subject  to  the  informational  requirements  of  the
Securities  Exchange  Act of 1934,  as  amended  (the  "Exchange  Act"),  and in
accordance therewith files reports,  proxy statements and other information with
the Securities and Exchange  Commission (the "Commission").  The reports,  proxy
statements and other information filed by the Company with the Commission may be
inspected  and  copied at the  public  reference  facilities  maintained  by the
Commission at Room 1024,  Judiciary Plaza, 450 Fifth Street,  N.W.,  Washington,
D.C. 20549, and at the Commission's regional offices at Room 3190,  Northwestern
Atrium Center, 500 West Madison Street, Suite 1400, Chicago, Illinois 60661; and
Seven World Trade Center,  13th Floor, New York, New York 10048.  Copies of such
material may be obtained from the Public Reference  Section of the Commission at
Room 1024,  Judiciary Plaza, 450 Fifth Street, N.W.,  Washington,  D.C. 20549 at
prescribed rates.

        The Company has filed with the  Commission a  Registration  Statement on
Form S-3 (the "Registration Statement") under the Securities Act with respect to
the Common Stock offered  hereby.  This  Prospectus  does not contain all of the
information  set  forth  in the  Registration  Statement  and the  exhibits  and
schedules filed as a part thereof,  as permitted by the Rules and Regulations of
the  Commission.  For further  information  with  respect to the Company and the
Common Stock, reference is hereby made to such Registration Statement, including
the exhibits and schedules filed as a part thereof. Statements contained in this
Prospectus  as to the  contents of any  contract or other  document  referred to
herein are not necessarily complete and where such contract or other document is
an exhibit to the  Registration  Statement,  each such statement is qualified in
all respects by the  provisions  of such exhibit,  to which  reference is hereby
made for a full statement of the provisions thereof. The Registration Statement,
including the exhibits and schedules  filed as a part thereof,  may be inspected
without charge at the public reference  facilities  maintained by the Commission
as set  forth in the  preceding  paragraph.  Copies  of these  documents  may be
obtained at prescribed rates from the Public Reference Section of the Commission
at Room 1024, Judiciary Plaza, 450 Fifth Street, N.W., Washington, D.C. 20549.


                 INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

        The following  documents  filed by the Company with the  Commission  are
incorporated by reference in this Prospectus and made a part hereof:
   

        (i)    Annual Report on Form 10-K for the fiscal year ended December 31,
               1995  as  amended by Amendment on  Form  10-K/A  and Amendment on
               Form  10-K/A-2.

        (ii)   Definitive  Proxy   Statement  dated   May  14,  1996,  filed  in
               connection   with  the   Company's   1996   Annual   Meeting   of
               Stockholders.

        (iii)  Report on Form 8-K dated March 13, 1996.

         (iv)  Quarterly  Report  on  Form 10-Q  for the period ending March 31,
               1996.

         (v)   The  description of the Company's  Common Stock  contained in its
               registration  statement on Form 8-A, File No. 0-16132,  including
               any  amendment or report  filed for the purpose of updating  such
               description.
    

        All documents filed by the Company pursuant to Section 13(a),  13(c), 14
or 15(d) of the Exchange Act subsequent to the date of this Prospectus and prior
to the  termination  of this  offering  shall be  deemed to be  incorporated  by
reference  in this  Prospectus  and to be a part  hereof from the date of filing
such documents.  Any statement contained in a document incorporated by reference
herein  shall be  deemed to be  modified  or  superseded  for  purposes  of this
Prospectus  to  the  extent  that  a  statement  contained  herein  modifies  or
supersedes  such statement.  Any such statement so modified or superseded  shall
not be deemed, except as so modified or superseded, to constitute a part of this
Prospectus.

        The Company will provide,  upon written or oral request,  without charge
to each person to whom a copy of this Prospectus has been  delivered,  a copy of
any or all of the  documents  which  have  been or may be  incorporated  in this
Prospectus by reference, other than certain exhibits to such documents. Requests
for such copies should be directed to: Secretary,  Celgene Corporation, 7 Powder
Horn Drive, Warren, New Jersey 07059; (908) 271-1001.

                                        2

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                                   THE COMPANY

        The  Company  attempts  to  develop  and  produce  innovative   products
addressing two major markets: high purity chiral chemical  intermediates for use
in  the  production  of  pharmaceuticals,   food  additives,   and  agricultural
chemicals;  and  therapeutics  for treatment of certain severe  inflammatory and
degenerative conditions associated with an over-response of the immune system.

Recent Development

        On March 13, 1996,  the Company  completed the private  placement of 503
shares of Series A Convertible  Preferred Stock (the "Preferred  Stock"),  which
were sold and issued to accredited  investors (the  "Investors")  pursuant to an
exemption from the  registration  requirements of the Securities Act provided by
Regulation  D  thereof.  Pursuant  to the terms of the  Subscription  Agreements
between the Company and the Investors by which the shares of the Preferred Stock
were sold, resales of the shares of Common Stock issuable upon conversion of the
Preferred Stock are being registered by the Company on a Registration  Statement
on Form S-3, of which this Prospectus forms a part. Pursuant to the Registration
Statement, all of the shares of Common Stock may be offered from time to time by
the Selling Stockholders.  The Preferred Stock contains rights,  preferences and
privileges,  including  a  provision  that  resets the  conversion  price of the
Preferred Stock to the lesser of the initial  conversion  price of $18.81 or 90%
of average  closing  market  price of the Common Stock for the seven (7) trading
days prior to the date of  conversion.  See  "Description  of  Capital  Stock --
Series A Convertible Preferred Stock."

        The  Company's  principal  office is  located  at 7 Powder  Horn  Drive,
Warren,  New Jersey 07059,  and its telephone and fax numbers are (908) 271-1001
and (908) 805-3931, respectively.


                                        3

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                                  RISK FACTORS

FORWARD LOOKING STATEMENTS

        Certain  information  contained  in this  Prospectus  and the  documents
incorporated  by reference  herein are  forward-looking  statements  (within the
meaning of Section  27A of the  Securities  Act of 1933 and  Section  21E of the
Securities  Exchange  Act of  1934).  Factors  set forth in the  following  Risk
Factors could affect the Company's  actual results and could cause the Company's
actual results to differ materially from those expressed  in any forward-looking
statements  made by, or on behalf of, the  Company  in this  Prospectus  and the
documents incorporated by reference herein.  Prospective investors in the shares
of the Company's  Common Stock  offered  hereby  should  carefully  consider the
following  Risk Factors,  in addition to the other  information  appearing in or
incorporated by reference into this Prospectus.

        Early Stages of Product Development.  Many of the Company's products and
processes  are in the early  stages of  development.  To date,  the  Company has
produced and sold only small quantities of certain chiral chemical intermediates
and is in clinical trials for SYNOVIR'tm', the Company's version of thalidomide.
The  Company's  immunotherapeutic  compounds  and  the  products  in  which  the
Company's  chiral  intermediates  are used  will  require  further  development,
testing  and  regulatory   approvals,   and  there  can  be  no  assurance  that
commercially viable products will result from these efforts.

        Lack of Manufacturing  Capability;  Limited Marketing Capability.  While
the Company has developed  expertise in the  production of certain of its chiral
products in developmental  quantities,  the Company  currently has no experience
in, or facilities for, manufacturing such chiral products on a commercial scale.
For the foreseeable future, the Company intends to utilize outside manufacturers
to produce  the  Company's  products  on a  commercial  scale and to seek to add
manufacturing capacity through alliances with third parties.

        In addition,  although the Company's direct sales force is marketing its
chiral  intermediate  products,  such  sales  force  is  very  limited.  For the
foreseeable  future,  the Company intends to continue its marketing  through its
direct sales force. The Company has not hired a sales force,  either internal or
external,  for its immunotherapeutic  products since all such products are still
in the  development  phase. If such products  receive  approval from the FDA, of
which there can be no assurance,  the Company will either develop its own sales,
marketing and distribution  resources or rely on a corporate  partner to provide
such services.

        Historical  Losses and Accumulated  Deficits.  The Company has sustained
losses in each year  since its  incorporation  in 1986.  It is likely  that such
losses will  continue  until the Company can produce and sell its  products on a
commercial  scale, if ever, and achieve  profitability by creating  economies of
scale,  reducing costs, and  establishing  its products in the  marketplace,  of
which there can be no assurance.

        Cash  Requirements.  Over the near term,  the  Company  expects to incur
substantial expenditures to further its immunotherapeutics program and to expand
its chiral  business.  At December  31,  1995 and for the year then  ended,  the
Company had cash and  temporary  investments  of $14.2 million and a net loss of
$10.5  million for 1995.  In March 1996,  the Company  received  net proceeds of
approximately $23.8 million from the sale of shares of the Preferred Stock.

        In view of the  Company's  continuing  losses,  the Company will have to
obtain  sufficient  funds to meet its cash  requirements  through  alliances  or
partnerships  with  compatible  entities with resources to support its programs,
the sale of assets or securities, other financing arrangements,  and operations.
However,  no  assurance  may be given that the  Company  will be  successful  in
raising additional funds or entering into business alliances. In addition, there
can be no assurance  that the Company will be  profitable  or have positive cash
flow at any time in the future even if the Company  succeeds in raising funds or
entering into business alliances.

                                        4

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        No Assurance  of  Proprietary  Protection.  The  Company's  success will
depend,  in part,  on its  ability  to obtain  patents,  maintain  trade  secret
protection,  and conduct its  business in the United  States and abroad  without
infringing  the  proprietary  rights of others.  Although the Company  possesses
certain  U.S.  patents and has filed U.S.  patent  applications  with respect to
certain of its products and technologies,  there can be no assurance that others
will not  develop and market  competing  technologies  and  products or that the
Company will be able to enforce the patents which it currently possesses or will
be able  otherwise  to obtain or enforce  any  patents for which it has filed an
application.  The  Company  also relies upon  unpatented  proprietary  and trade
secret  technology.  There can be no assurance that others have not developed or
will not independently  develop such proprietary  technology or otherwise obtain
access to the Company's proprietary technology.  The extent to which the Company
in the future may be required or may desire to obtain  licenses  with respect to
patents  obtained by others and the  availability  and cost of any such licenses
are currently unknown.  If the Company does not obtain necessary  licenses,  the
development, production, use, or sale of the Company's products could be delayed
or  prevented.  In  addition,  the  Company  could  incur  substantial  costs in
defending  any patent  infringement  suits or in  asserting  any patent  rights,
including those granted by third parties.

        Governmental Regulation. The regulatory process for a new pharmaceutical
is a combination of a number of stages.  The FDA approval  process begins with a
notice of claimed IND, which is  essentially a proposal to obtain  permission to
begin  testing  on  human  subjects.  Prior  to  the  filing  of  the  IND  much
pre-clinical  testing has already been done.  Once an IND is obtained,  clinical
studies are  initiated.  The FDA closely  monitors  the progress of the clinical
testing, and may, at its discretion,  reevaluate,  alter,  suspend, or terminate
testing based on the data  accumulated  and its  assessment of the  risk/benefit
ratio to the patient.  Upon  successful  completion  of the  required  phases of
clinical  testing,  a new  drug  application  (NDA)  is  filed  and  the FDA may
authorize the marketing of the new pharmaceutical  for the proposed  indication.
The entire discovery and development process often takes many years.

        SYNOVIR, the Company's version of thalidomide, is currently in a pivotal
clinical study to determine its effectiveness in treating cachexia  (wasting) in
AIDS  patients,  which  trials  the  Company is  funding.  SYNOVIR is also being
evaluated by the Company and others in additional  early-stage clinical studies:
cachexia  associated  with cancer,  progression of HIV/AIDS,  as co-therapy with
interleukin  2 (IL-2) for patients  with  HIV/AIDS,  and  rheumatoid  arthritis.
Additional studies are planned including the evaluation of SYNOVIR for treatment
of  diarrhea  in patients  with AIDS  (study to be funded by the  Company).  The
testing of SYNOVIR has been,  and the Company  believes that it will continue to
be, a time-consuming and costly process. It is difficult to predict how long FDA
approval  for any  indication  will take and whether any such  approval  will be
granted.

        Substantially all of the Company's current chiral intermediate  products
may be components of  pharmaceutical  and  agrochemical  products  developed and
marketed  by  others.  The  testing,   marketing,   and  manufacturing  of  such
pharmaceutical  products will require  regulatory  approval.  It is difficult to
predict how long such approvals will take and whether any such approvals will be
granted. In addition,  if the Company produces proprietary chiral products,  the
testing,   marketing,   and  manufacturing  of  such  products  will  likely  be
time-consuming  and  costly  and will  require  regulatory  approval,  including
approval from the FDA.

        Delays  in  obtaining,  or the  failure  to  obtain,  FDA and any  other
necessary  regulatory  approvals of the  Company's  proprietary  products or the
pharmaceutical  products in which the  Company's  products  are to be  included,
would have an adverse  effect on the Company.  To the extent that the  Company's
success will depend on any regulatory  approvals from  governmental  authorities
outside  of the  United  States  that  perform a role  similar  to the FDA,  the
uncertainties similar to those described above may exist.

        Product  Liability.  The Company may be subject to product  liability or
other claims if the use of its technology or products (SYNOVIR,  NCEs, or chiral
intermediates) is alleged to have resulted in adverse effects. Thalidomide, when
used by pregnant women, has and can result in serious birth defects.  Therefore,
if  SYNOVIR  is  approved  by the FDA,  necessary  precautions  must be taken by
physicians  prescribing the drug to women of child-

                                        5

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bearing potential.  Although it is the present intention of the Company to apply
for product liability insurance,  there can be no assurance that it will be able
to obtain  coverage at  economically  feasible rates or that such  coverage,  if
obtained,  will be  adequate  to protect the Company in the event of such claims
against  it.  The  obligation  to pay any  product  liability  claim  may have a
material adverse effect on the business or financial condition of the Company.

        Dependence Upon Third Parties.  Since substantially all of the Company's
current  chiral  intermediate  products may be components of  pharmaceutical  or
agrochemical  products  developed  and  marketed  by others,  the success of the
Company's products is dependent upon third parties over which the Company has no
control.  Such  third  parties  may fail to pursue or fund those  products  that
include the Company's products whether due to lack of resources or interest.

        The Company's  ability to  commercialize  SYNOVIR and other  proprietary
products, if developed, may depend upon its ability to enter into joint ventures
or  other  arrangements  with  established  pharmaceutical  companies  with  the
requisite  experience and financial and other resources to conduct the necessary
testing  of  such  products  in  order  to  obtain  regulatory  approval  and to
manufacture and market such products.

        Dependence Upon Reimbursement.  Sales of the Company's products, if any,
will be dependent in part on the availability of reimbursement  from third party
payors, such as governmental and private insurance plans. Third party payors are
increasingly  challenging the prices charged for medical  products and services.
Additionally,  the  containment  of health care costs has become a priority  and
pharmaceutical  and biotechnology drug prices have been targeted in this effort.
If the  Company  succeeds in bringing  any  products to market,  there can be no
assurance   that  such  products  will  be   considered   cost-effective,   that
reimbursement   will  be  available  or,  if   available,   that  the  level  of
reimbursement  will be sufficient to allow the Company to sell its products on a
profitable basis.

        Competition   and   Technological   Change.   The  fine   chemical   and
pharmaceutical  therapeutics businesses in which the Company competes are highly
competitive.  Competitors  include major chemical and  pharmaceutical  companies
that employ both biochemical and conventional technology, as well as specialized
biotechnology   firms.  Most  of  these  companies  have  considerably   greater
financial, technical, and marketing resources than the Company. The Company also
experiences  competition  in the  development of its products and processes from
universities and other research  institutions  and, in some instances,  competes
with others in acquiring  technology  from such  sources.  The fine chemical and
pharmaceutical  industries  have  undergone,  and are  expected  to  continue to
undergo,  rapid and significant  technological  change,  and the Company expects
competition to intensify as technical advances in each field are made and become
more widely known.

   
        Key Personnel. The success of the Company will depend, in large part, on
its  ability  to  continue  to  attract  and  retain  qualified  scientific  and
management personnel. Competition for such personnel is intense and there can be
no assurance  that the Company will be able to attract and retain such  persons.
The loss of the Company's key management or scientific  personnel including John
W.  Jackson,  Chairman  and  Chief  Executive  Officer,  and  Dr.  Sol J. Barer,
President, could have a material adverse effect on the Company. The Company does
not maintain  key man life insurance coverage on the lives of either Mr. Jackson
or Dr. Barer.

        Shares Eligible for Future Sale. Future sales of substantial  amounts of
Common Stock could adversely affect the prevailing market price of the Company's
Common Stock.  If all of the outstanding  shares of  Preferred  Stock and all of
the  outstanding  8% Convertible  Debentures  had been converted on May 24, 1996
based on the closing price of the Common Stock for the seven trading days  ended
May  23,  1996  (including  accretion and accrued  interest through  that date),
approximately  1,690,000  shares of  Common  Stock would  have been  issued as a
result of the conversion of shares of Preferred Stock and approximately  380,000
shares of Common Stock would have been issued as a result  of  the conversion of
Convertible  Debentures.  Furthermore,  should the  trading price  of the Common
Stock  decline prior  to  the  conversion  of all shares of the Preferred  Stock
or  Convertible Debentures,  the number of shares of Common Stock issuable  upon
conversion  of  such   Preferred   Stock or Convertible Debentures will increase
proportionately.  See  "Description  of  Capital Stock -- Series  A  Convertible
Preferred"  and  "Other Securities of the Company -- 8% Convertible Debentures."
In addition,  if the trading price of Common Stock  declines  below $11.50,  the
Company may elect to defer conversions of the Preferred Stock for up to 90 days,
and, with the consent of the holders,  up to 180 days, in which case the Company
would be required to issue to the holders warrants to purchase  shares of Common
Stock  equivalent  to as much as 20% of the shares that would have been issuable
upon  conversion  of the  Preferred  Stock if effected at $11.50.  See  "Selling
Stockholders"  and  "Description  of  Capital  Stock  --  Series  A  Convertible
Preferred -- Protective Provisions."
    



                                       6
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        Dilution.  The current  trading price of the  securities  issued in this
offering is substantially  higher than the book value per share of Common Stock.
Investors  purchasing  securities in this offering therefore are likely to incur
immediate, substantial dilution.

        Dividends on  Common Stock Unlikely.   The  Company  does  not,  in  the
foreseeable  future, anticipate paying any dividends on the Common Stock.

        Volatility of Common Stock Price. There has been significant  volatility
in the market  prices for publicly  traded  shares of  biotechnology  companies,
including  the Company.  There can be no assurance  that the price of the Common
Stock will remain at or exceed current levels.  Factors such as announcements of
technical  or  product   developments   by  the  Company  or  its   competitors,
governmental regulation, or patent or proprietary rights developments may have a
significant impact on the market price of the Common Stock.


                                 USE OF PROCEEDS

        The shares of Common Stock being  offered  hereby are for the account of
the Selling Stockholders.  Accordingly,  the Company will not receive any of the
proceeds  from  the  sale of the  shares  being  offered  hereby.  See  "Selling
Stockholders."


                              SELLING STOCKHOLDERS

        The  table on the  following  page sets  forth the name of each  Selling
Stockholder,  the number of shares of Common  Stock  beneficially  owned by each
Selling  Stockholder as of April 1, 1996 (based on  information  supplied by the
Selling  Stockholders to the Company),  and the number of shares of Common Stock
being offered hereby by each Selling Stockholder.

        The shares being  offered by the Selling  Stockholders  were acquired or
will be  acquired  from the  Company  either  (i)  following  conversion  of the
Preferred  Stock;  (ii) upon  exercise of warrants  acquired from the Company by
persons  affiliated with Swartz  Investments,  LLC ("Swartz  Investments"),  the
placement  agent for the  Preferred  Stock;  (iii)  upon  exercise  of  warrants
acquired  from the Company by Swartz  Investments,  as  placement  agent for the
Company's  Regulation S Offering of 8% Convertible  Debentures in July 1995, and
subsequently transferred to persons affiliated with Swartz Investments;  or (iv)
upon exercise of warrants  acquired from the Company by a public  relations firm
as partial  compensation for services rendered to the Company.  See "Description
of Capital Stock -- Warrants."

        The Company will not receive any of the proceeds  from the sales of such
shares.  The number of shares that may be  actually  sold by each of the Selling
Stockholders will be determined by such Selling Stockholder. Because each of the
Selling  Stockholders  may sell all,  some or none of the shares of Common Stock
which each holds,  and because the Offering  contemplated  by this Prospectus is
not currently being  underwritten,  no estimate can be given as to the number of
shares  of  Common  Stock  that will be held by the  Selling  Stockholders  upon
termination of the Offering. See "Plan of Distribution."


                                       7
<PAGE>
<PAGE>



<TABLE>
<CAPTION>


                                                      Number of Shares   Number of shares
Name of Selling Stockholder                          Beneficially Owned  offered hereby (1)
<S>                                                        <C>                <C>   
AG Arb Partners, L.P.(2)                                     57,972           57,972
AG Super Fund International Partners, L.P.(3)                46,378           46,378
AG Super Fund, L.P.(4)                                       57,972           57,972
Ace Foundation, Inc.(5)                                      46,378           46,378
Angelo, Gordon & Co., L.P.(6)                                57,972           57,972
Banque Scandinave En Suisse(7)                              139,132          139,132
Canadian Imperial Holdings, Inc.(8)                         347,828          347,828
Capital Ventures International(9)                           289,856          289,856
Chaim Gross(10)                                             115,943          115,943
Everest Capital Fund L.P.(11)                               150,725          150,725
Everest Capital International Ltd.(12)                      313,044          313,044
Faisal Finance(13)                                          115,943          115,943
GAM Arbitrage Investments, Inc.(14)                          57,972           57,972
Gershon Partners, L.P.(15)                                   46,378           46,378
Iliad Partners I, L.P.(16)                                  115,943          115,943
Halifax Fund, L.P.(17)                                       23,189           23,189
KA Trading, L.P.(18)                                         57,972           57,972
Kessler Asher Group Limited Partnership(19)                  57,972           57,972
Koch Realty, Inc.(20)                                       115,943          115,943
Leonardo, L.P.(21)                                           34,784           34,784
Michael Angelo, L.P.(22)                                     34,784           34,784
Nelson Partners(23)                                         508,385          231,885
Nutmeg Partners, L.P.(24)                                    57,972           57,972
OVDA Fund Ltd.(25)                                           34,784           34,784
Olympus Securities, Ltd.(26)                                135,693          115,943
Ramius Fund Ltd.(27)                                         46,378           46,378
Raphael, L.P.(28)                                            57,972           57,972
Richcourt $ Strategies, Inc.(29)                             57,972           57,972
West Merchant Bank Ltd.(30)                                  28,986           28,986
Sunder Advani (31)                                            1,459            1,459
Lance T. Bury (32)                                            3,500            3,500
Dunwoody Brokerage Services, Inc.(33)                        13,500           13,500
Enigma Investments Ltd (34)                                   8,500            8,500
Global Equity, Inc. (35)                                      9,375            9,375
P. Bradford Hathorn (36)                                      8,500            8,500
Davis C. Holden (37)                                          1,000            1,000
Michael C. Kendrick (38)                                     57,351           57,351
Charles Krusen (39)                                           3,316            3,316
David K. Peteler (40)                                         8,000            8,000
Redington, Inc. (41)                                         50,000           50,000
Eric Stephan Swartz (42)                                     57,352           57,352
</TABLE>

- -------------------------------------------------------------------


                                       8
<PAGE>
<PAGE>



(1)  All shares  amounts  with respect to shares  issuable  upon the exercise of
     shares of Series A  Convertible  Preferred  Stock (the  "Preferred  Stock")
     assume a conversion price of $10.35,  without giving effect to the issuance
     of shares as a result of any accretion.  The actual conversion price may be
     higher  or lower  than  $10.35  and the  amount  of  accretion  will  vary,
     depending upon the period over which Preferred Stock is outstanding.  Thus,
     the number of shares  actually  issued pursuant to the conversion of shares
     of Preferred  Stock for any one Selling  Stockholder may be higher or lower
     than the number set forth in the table.  See  "Description of Capital Stock
     -- Series A  Convertible  Preferred."  In addition,  all such share amounts
     include a 20% premium to allow for "lock-up"   warrants  that may be issued
     pursuant  to  the  protective   provisions  of  the  Preferred  Stock.  See
     "Description  of  Capital  Stock  --  Series  A  Convertible  Preferred  --
     Protective Provisions."
(2)  Includes  shares  issuable  upon the  conversion  of 10 shares of Preferred
     Stock.
(3)  Includes  shares  issuable  upon the  conversion  of 8 shares of  Preferred
     Stock.
(4)  Includes  shares  issuable  upon the  conversion  of 10 shares of Preferred
     Stock.
(5)  Includes  shares  issuable  upon the  conversion  of 8 shares of  Preferred
     Stock.
(6)  Includes  shares  issuable  upon the  conversion  of 10 shares of Preferred
     Stock.
(7)  Includes  shares  issuable  upon the  conversion  of 24 shares of Preferred
     Stock.
(8)  Includes  shares  issuable  upon the  conversion  of 60 shares of Preferred
     Stock.
(9)  Includes  shares  issuable  upon the  conversion  of 50 shares of Preferred
     Stock.
(10) Includes  shares  issuable  upon the  conversion  of 20 shares of Preferred
     Stock.
(11) Includes  shares  issuable  upon the  conversion  of 26 shares of Preferred
     Stock.
(12) Includes  shares  issuable  upon the  conversion  of 54 shares of Preferred
     Stock.
(13) Includes  shares  issuable  upon the  conversion  of 20 shares of Preferred
     Stock.
(14) Includes  shares  issuable  upon the  conversion  of 10 shares of Preferred
     Stock.
(15) Includes  shares  issuable  upon the  conversion  of 8 shares of  Preferred
     Stock.
(16) Includes  shares  issuable  upon the  conversion  of 20 shares of Preferred
     Stock.
(17) Includes  shares  issuable  upon the  conversion  of 4 shares of  Preferred
     Stock.
(18) Includes  shares  issuable  upon the  conversion  of 10 shares of Preferred
     Stock.
(19) Includes  shares  issuable  upon the  conversion  of 10 shares of Preferred
     Stock.
(20) Includes  shares  issuable  upon the  conversion  of 20 shares of Preferred
     Stock.
(21) Includes  shares  issuable  upon the  conversion  of 6 shares of  Preferred
     Stock.
(22) Includes  shares  issuable  upon the  conversion  of 6 shares of  Preferred
     Stock.
(23) Includes  shares  issuable  upon the  conversion  of 40 shares of Preferred
     Stock and upon the conversion of 8% convertible debentures in the principal
     amount of $2.1 million, plus accrued interest.
(24) Includes  shares  issuable  upon the  conversion  of 10 shares of Preferred
     Stock.
(25) Includes  shares  issuable  upon the  conversion  of 6 shares of  Preferred
     Stock.
(26) Includes  shares  issuable  upon the  conversion  of 20 shares of Preferred
     Stock,  and  upon  the  conversion  of 8%  convertible  debentures  in  the
     principal amount of $150,000, plus accrued interest.
(27) Includes  shares  issuable  upon the  conversion  of 8 shares of  Preferred
     Stock.
(28) Includes  shares  issuable  upon the  conversion  of 10 shares of Preferred
     Stock.
(29) Includes  shares  issuable  upon the  conversion  of 10 shares of Preferred
     Stock.
(30) Includes  shares  issuable  upon the  conversion  of 5 shares of  Preferred
     Stock.
(31) Mr. Advani is affiliated with Swartz Investments;  includes shares issuable
     upon the exercise of warrants to purchase 1,459 shares.
(32) Mr. Bury is affiliated  with Swartz  Investments;  includes shares issuable
     upon the exercise of warrants to purchase 3,500 shares.
(33) Dunwoody Brokerage Services is affiliated with Swartz Investments; includes
     shares issuable upon the exercise of warrants to purchase 13,500 shares.
(34) Enigma  Investments  Ltd. is affiliated with Swartz  Investments;  includes
     shares issuable upon the exercise of warrants to purchase 8,500 shares.
(35) Global  Equity is  affiliated  with  Swartz  Investments;  includes  shares
     issuable upon the exercise of warrants to purchase 9,375 shares.
(36) Mr. Hathorn is affiliated with Swartz Investments; includes shares issuable
     upon the exercise of warrants to purchase 8,500 shares.
(37) Mr. Holden is affiliated with Swartz Investments;  includes shares issuable
     upon the exercise of warrants to purchase 1,000 shares.
(38) Mr.  Kendrick  is  affiliated  with  Swartz  Investments;  includes  shares
     issuable upon the exercise of warrants to purchase 57,351 shares.
(39) Mr. Krusen is affiliated with Swartz Investments;  includes shares issuable
     upon the exercise of warrants to purchase 3,316 shares.
(40) Mr. Peteler is affiliated with Swartz Investments; includes shares issuable
     upon the exercise of warrants to purchase 8,000 shares.
(41) Includes  shares  issuable upon the exercise of warrants to purchase 50,000
     shares.
(42) Mr. Swartz is affiliated with Swartz Investments;  includes shares issuable
     upon the exercise of warrants to purchase 57,352 shares.


                                       9
<PAGE>
<PAGE>




        This Registration Statement shall also cover additional shares of Common
Stock which become  issuable in connection  with the shares  registered for sale
hereby by reason of any stock dividend,  stock split,  recapitalization or other
similar transaction  effected without the receipt of consideration which results
in an increase in the number of the  Registrant's  outstanding  shares of Common
Stock.

        On  March  11 and  12,  1996,  the  Company  entered  into  Subscription
Agreements with each of the Selling Stockholders who participated in the Private
Placement pursuant to which such persons purchased an aggregate of 503 shares of
Preferred  Stock.  Each  person that  purchased  Preferred  Stock  pursuant to a
Subscription  Agreement  represented  to the Company  that it would  acquire the
shares for investment and with no present  intention of distributing any of such
shares  except  pursuant  to  this  Prospectus.  Pursuant  to  the  Subscription
Agreements,  the Company  agreed to file,  and has filed,  with the  Commission,
under the Act, a  Registration  Statement on Form S-3, of which this  Prospectus
forms a part,  with  respect  to the  resale of the shares and agreed to use its
best efforts to keep such  Registration  Statement  effective until such date as
all of the shares  have been  resold,  or such time as all of the shares held by
the Selling  Stockholders  can be sold immediately  without  compliance with the
registration requirement of the Securities Act pursuant to Rule 144.

        In February 1996, the Company  engaged Swartz  Investments to advise the
Company in connection with the structure,  terms,  and conditions of a preferred
stock  offering  and  to  introduce  the  Company  to  potential  investors.  In
consideration for their services, Swartz Investments was paid a placement fee of
$1,131,750  plus a   non-accountable  expense  allowance  of  $188,625  for  its
expenses,  including  legal  expenses,  in connection with the offering and also
issued to persons affiliated with Swartz Investments warrants to purchase 66,853
shares of Common Stock.  Such warrants are  exercisable for a term of five years
at $20.52 per share of Common  Stock.  The Company has also agreed to  indemnify
the  Agent  against  certain  liabilities,   including   liabilities  under  the
Securities Act.

        In July, 1995, the Company also retained Swartz Investments to represent
the Company in connection with  negotiating and structuring a private  placement
offering of $12  million of  Convertible  Debentures.  In that  connection,  the
Company  paid the  agent a  placement  agent fee and a  non-accountable  expense
allowance that totaled $840,000,  and also issued to Swartz Investments warrants
to purchase 105,000 shares of Common Stock. The Company also agreed to indemnify
Swartz Investments from any losses that Swartz Investments may incur arising out
of  such  engagement.   The  warrants  to  purchase  105,000  were  subsequently
transferred to persons affiliated with Swartz Investments.

        Each Selling  Stockholder  affiliated with Swartz  Investments shared in
the compensation paid to Swartz  Investments in connection with the placement of
the Preferred Stock and the placement of the 8% Convertible Debentures.

        Pursuant to an agreement entered into in November, 1994, Redington, Inc.
provides investor relations services to the Company.  In exchange,  Redington is
paid on an as-billed  basis  approximately  $188,000 per year and received a one
time grant of warrants to purchase  50,000 shares of the Company's  common stock
exercisable  through  September 1, 1999, at an exercise price of $6.50 per share
of  common  stock.  The  Company  agreed  to use its  best  efforts  to  provide
registered  stock upon the  exercise of the  warrants.  The  Agreement  provided
customary indemnification provisions.

        In connection with the offering made hereby, the Company and the Selling
Stockholders  have entered into an agreement that contains certain indemnity and
contribution  provisions  between  the  Company  and such  Selling  Stockholders
against certain liabilities,  including liabilities arising under the Securities
Act.  The  Company  has agreed to bear  certain  expenses  (other  than  selling
commissions) in connection  with the  registration of the shares of Common Stock
offered hereby.

        Other than as disclosed herein, none of the Selling Stockholders has had
any position,  office or material  relationship with the Company within the past
three years.


                                       10
<PAGE>
<PAGE>

                              PLAN OF DISTRIBUTION

        The sale of the shares by the Selling  Stockholders may be effected from
time to time in transactions (which may include block transactions by or for the
account  of the  Selling  Stockholders)  in the  over-the-counter  market  or in
negotiated transactions,  through the writing of options on such shares (whether
they be exchange  listed  options or  otherwise),  short sales, a combination of
such methods of sale, or otherwise.  Sales may be made at fixed prices which may
be changed,  at market  prices  prevailing at the time of sale, or at negotiated
prices.

        Selling  Stockholders  may effect  such  transactions  by selling  their
shares directly to purchasers,  through  broker-dealers acting as agents for the
Selling Stockholders, or to broker-dealers who may purchase shares as principals
and thereafter sell the shares from time to time in the over-the-counter market,
in negotiated  transactions,  or  otherwise.  Such  broker-dealers,  if any, may
receive compensation in the form of discounts,  concessions, or commissions from
the Selling  Stockholders and/or the purchasers for whom such broker-dealers may
act as agents or to whom they may sell as principals or both (which compensation
as to a particular broker-dealer may be in excess of customary commissions).

        In order to  comply  with the  securities  laws of  certain  states,  if
applicable,  the  shares  will  be  sold  in  such  jurisdictions  only  through
registered or licensed  brokers or dealers.  In addition,  in certain states the
shares may not be sold unless they have been registered or qualified for sale in
the applicable  state or an exemption  from the  registration  or  qualification
requirement  is  available  and is complied  with by the Company and the Selling
Stockholders.

        The  Selling   Stockholders  and  broker-dealers,   if  any,  acting  in
connection  with such  sale  might be deemed  to be  "underwriters"  within  the
meaning of Section 2(11) of the Securities  Act and any  commission  received by
them  and any  profit  on the  resale  of such  shares  might  be  deemed  to be
underwriting discounts and commissions under the Securities Act.

        Under  applicable  rules and  regulations  under the  Exchange  Act, any
person engaged in the distribution of the shares may not  simultaneously  engage
in market making  activities with respect to the Common Stock of the Company for
a period of two business days prior to the commencement of such distribution. In
addition and without  limiting the foregoing,  each Selling  Stockholder will be
subject  to  applicable  provisions  of the  Exchange  Act  and  the  rules  and
regulations thereunder,  including,  without limitation,  Rules 10b-6 and 10b-7,
which  provisions  may limit the timing of purchases  and sales of shares of the
Company's Common Stock by the Selling Stockholders.

   

                          DESCRIPTION OF CAPITAL STOCK

        The Company has 25,000,000 shares of authorized  capital stock, of which
20,000,000  shares  have been  designated  Common  Stock,  $0.01 par value,  and
5,000,000  shares have been  designated  Preferred  Stock,  $0.01 par value (the
"Preferred Stock") of which 520 shares have been designated Series A Convertible
Preferred Stock. The Company had 9,111,892 shares of Common Stock outstanding on
May 24, 1996 and 503 shares of Series A Convertible Preferred  Stock outstanding
on May 24, 1996.
    

Common Stock

        The Company is  authorized to issue  20,000,000  shares of Common Stock,
par value $.01 per share (the "Common  Stock").  The holders of Common Stock are
entitled  to one  vote  per  share  on  all  matters  to be  voted  upon  by the
stockholders.  Subject to the prior rights of the Series A Convertible Preferred
Stock and of other  series or  classes  hereafter  authorized  of the  Company's
preferred stock, par value $.01 per share having superior or pari passu dividend
rights to the Common Stock,  the holders of Common Stock are entitled to receive
such lawful dividends as may be declared by the Board of Directors. In the event
of the liquidation,  dissolution,  or winding up of the Company,  subject to the
prior  rights of Series A  Convertible  Preferred  Stock and any other series or
classes of 



                                       11
<PAGE>
<PAGE>

Preferred Stock having superior or pari passu  liquidation  rights to the Common
Stock,  the holders of Common Stock are entitled to share  ratably in all of the
assets of the Company available for distribution to its stockholders.  There are
no redemption or sinking fund provisions  applicable to the Common Stock. All of
the  outstanding  shares of Common  Stock are validly  issued,  fully paid,  and
non-assessable. Holders of Common Stock do not have preemptive rights.

Preferred Stock -- General

        The Company is authorized to issue 5,000,000  shares of preferred stock,
par value $.01,  of which 503 shares  presently are issued and  outstanding  and
designated  as  Series  A  Convertible   Preferred  Stock.  Subject  to  certain
restrictions, the Board of Directors of the Company, without further stockholder
approval,  has the  authority to issue,  at any time and from time to time,  the
preferred  stock as preferred  stock of any series and, in  connection  with the
creation of each such series, to fix the number of shares of such series and the
powers,  designations,  preferences,  rights,  qualifications,  limitations, and
restrictions of such series to the full extent now or hereafter permitted by the
laws of the State of Delaware.

Series A Convertible Preferred Stock

        Liquidation  Rights.  In the event of any  liquidation,  dissolution  or
winding up of the Company,  either  voluntary or involuntary  ("an Event"),  the
holders  of  shares  shall  be  entitled  to  receive,   immediately  after  any
distributions  to  senior   securities  and  prior  and  in  preference  to  any
distribution to junior  securities but in parity with any distribution to parity
securities,  an  amount  per  share  equal  to the sum of (i)  $50,000  for each
outstanding Share (the "Original Series A Issue Price") and (ii) an amount equal
to 4.9% of the  Original  Series A Issue Price per annum for the period that has
passed since the date of issuance of any Series A  Convertible  Preferred  Stock
(such  amount  being  referred  to  herein  as the  "Accretion").  If  upon  the
occurrence of such Event and after any distributions to senior  securities,  the
assets and funds thus distributed  among the holders of the Series A Convertible
Preferred  Stock and  parity  securities  shall be  insufficient  to permit  the
payment to such holders of the full  preferential  amounts due to the holders of
the  Series  A   Convertible   Preferred   Stock  and  the  parity   securities,
respectively,  then the entire remaining assets and funds of the Company legally
available for distribution  shall be distributed among the holders of the Series
A Convertible Preferred Stock and the parity securities,  pro rata, based on the
respective liquidation amounts to which each such series of stock is entitled by
the  Company's   Certificate  of  Incorporation   and  any   Certificate(s)   of
Designation.  Upon the completion of this distribution,  if assets remain in the
Company, they shall be distributed to holders of junior securities in accordance
with the  Company's  Certificate  of  Incorporation  including  any duly adopted
Certificate(s) of Designation.  A consolidation or merger of the Company with or
into any other corporation or corporations, or a sale, conveyance or disposition
of all or substantially  all of the assets of the Company or the effectuation by
the Company of a  transaction  or series of related  transactions  in which more
than 50% of the voting  power of the Company is disposed of, shall not be deemed
to be a liquidation, dissolution or winding up.

        Voting Rights.  The holders of the Series A Convertible  Preferred Stock
have no voting rights except as otherwise required by Delaware law.

        Optional  Conversion.  The  record  holder of the  Series A  Convertible
Preferred Stock shall be entitled,  subject to the Company's right of redemption
and the  restrictions  on conversion,  to convert the shares held by such holder
into that number of fully-paid and  nonassessable  shares of the Common Stock at
the Conversion Rate as set forth below. The minimum number of shares of Series A
Convertible  Preferred  Stock  that may be  converted  is the  lesser of (i) two
shares or (ii) all of the holder's  remaining  shares.  The rate at which shares
may be converted into shares of Common Stock is  hereinafter  referred to as the
"Conversion Rate" and is computed as follows:

Number  of  shares  of  Common  Stock  issued  upon  conversion  of one share of
Preferred Stock = Principal Conversion Rate + Accretion Conversion Rate, where


                                       12
<PAGE>
<PAGE>

        "Principal Conversion Rate" =         Issue Price
                                         ----------------------
                                            Conversion Price

        and "Accretion Conversion Rate" =   (.049)(N/365)(Issue Price)
                                          ------------------------------
                                            Accretion Conversion Price

        where

        N = the number of days between (i) the date that, in connection with the
        consummation  of the initial  purchase of the  Preferred  Stock from the
        Company, the escrow agent first had in its possession funds representing
        full  payment  for the  Preferred  Stock for which  conversion  is being
        elected, and (ii) the Date of Conversion;

        Issue Price = the Original Series A Issue Price;

        Accretion  Conversion  Price shall be the average  Closing Price for the
        Common  Stock as that term is defined  below,  for the 30 calendar  days
        prior to the Date of Conversion; and

        Conversion  Price = the lesser of (x) $18.81,  or (y) 90% of the average
        Closing Price,  as that term is defined below,  of the Company's  Common
        Stock for the seven (7) trading days  immediately  preceding the Date of
        Conversion. For purposes hereof, the term "Closing Price" shall mean the
        closing price of the  Company's  Common Stock as reported by NASDAQ (or,
        if not reported by NASDAQ,  as reported by such other exchange or market
        where traded).

        Restrictions on Conversion.  No shares of Series A Convertible Preferred
Stock may be converted prior to May 12, 1996. Thereafter,  each holder of Series
A Convertible  Preferred Stock may convert  one-third of such shares on or after
May 12,  1996,  an  additional  one-third  on or after  June 11,  1996,  and all
additional  remaining shares on or after July 11, 1996. All conversions are also
subject to the Company's  right of redemption and to the Protective  Provisions,
as described below.

        Automatic  Conversion.  The shares shall automatically be converted into
Common Stock (in  accordance  with the  conversion  price  provisions  above but
subject to the Protective Provisions below) on March 13, 1998.

        Redemption at Option of Company.  In the event the average Closing Price
of the  Company's  Common  Stock on the  NASDAQ for the seven (7)  trading  days
immediately  preceding the Date of  Conversion  shall be at or less than $18.81,
the Company  shall have the right,  in its sole  discretion,  upon  receipt of a
Notice of  Conversion,  to redeem in whole or in part any  Series A  Convertible
Preferred Stock submitted for conversion.  If the Company elects to redeem some,
but  not  all,  of the  Series  A  Convertible  Preferred  Stock  submitted  for
conversion,  the  Company  shall  redeem  from  among the  Series A  Convertible
Preferred  Stock  submitted for  conversion on the  applicable  date, a pro-rata
amount from each shareholder submitting Series A Convertible Preferred Stock for
conversion. The redemption price shall equal the sum of the Principal Redemption
Price plus the  Accretion.  The  Accretion  shall be payable,  at the  Company's
option, in cash or Common Stock. The Principal  Redemption Price shall equal the
Issue Price divided by the Conversion Price,  multiplied by the Closing Price on
Date of Conversion,  and the Accretion, if paid in shares of Common Stock, shall
be calculated as Accretion  divided by Accretion  Conversion Price, in each case
where  "N,"  "Issue  Price,"  "Closing  Price",  "Accretion  Conversion  Price",
"Accretion" and "Conversion Price" have the meanings set forth above.

        At any time after December 13, 1996, if the average closing price of the
Company's Common Stock for the seven (7) trading days immediately  preceding the
notice date is greater than $18.81,  the Company  shall have the right to redeem
the Series A Convertible Preferred Stock in increments of $1.5 million by giving
30 business days written notice of its intention to do so. The redemption  price
per share of Series A Convertible Preferred Stock shall be as follows:


                                       13
<PAGE>
<PAGE>



<TABLE>
<CAPTION>

        Redemption Price                    Elapsed Time since March 13, 1996
        ----------------                    ---------------------------------
<S>                                         <C>                           
        130% of Stated Value                9 months and 1 day - 12 months
        125% of Stated Value                12 months and 1 day - 18 months
        120% of Stated Value                18 months and 1 day - 24 months
</TABLE>

        "Stated  Value" shall equal the  Original  Series A Issue Price plus the
Accretion (calculated as of the effective date of such redemption).

        Protective Provisions. In the event the Closing Price per share shall be
at or less than $11.50 for each of the five (5) trading days  preceding the date
of submission of a Notice of  Conversion,  the Company shall have the right,  in
its  sole  discretion,  to  elect,  in lieu of  conversion,  (1) to  redeem  the
preferred  stock  presented  for  conversion  in  accordance  with the preceding
paragraph,  or (2) to declare such conversion null and void, and declare that no
conversion of any  Preferred  Stock that is included in the Notice of Conversion
(the "Affected  Preferred  Stock") shall be permitted for the subsequent  ninety
(90) day period (the "90 Day Lock-Up Period").

        In the event the Company  declares a 90 Day Lock-Up Period,  the Company
shall issue to the Holder of the  Affected  Preferred  Stock  warrants  ("90 Day
Lock-Up Warrants"),  to purchase Common Stock of the Company. The 90 Day Lock-Up
Warrants shall entitle the holder to purchase a number of shares of Common Stock
equal to 10% of the number of shares of Common Stock that would have been issued
upon conversion of the Affected Preferred Stock at a conversion price of $11.50.
The strike price of the 90 Day Lock-Up Warrant shall equal $11.50, and its terms
shall be two (2) years from the date of issuance.

        The Company may, in its  discretion,  offer to provide  another  warrant
("180 Day Lock-Up  Warrant"),  in addition  to the 90 Day  Lock-Up  Warrant,  to
purchase Common Stock of the Company,  to the holder of Affected Preferred Stock
in exchange for such holder's agreement to forebear from converting its Affected
Preferred  Stock for an additional  90 days beyond the 90 Day Lock-Up  Period (a
"180 Day Lock-up Period"). Upon written acceptance of such an offer, the Company
shall issue to the holder a 180 Day  Lock-Up  Warrant  which  shall  entitle the
holder to purchase a number of Common Stock equal to 10% of the number of shares
of Common  Stock that would have been issued  upon  conversion  of the  Affected
Preferred Stock at a conversion price of $11.50 for a term of two (2) years from
the date of issuance.  After any 90 Day Lock-Up Period or 180 Day Lock-Up Period
(as  applicable),  the holder  shall again be  entitled to convert the  Affected
Preferred Stock without any further Lock-Up restrictions.

Other Securities of the Company

        Warrants

        The Company has outstanding warrants to purchase an aggregate of 221,853
shares of the Company's  Common Stock.  Shares of Common Stock issuable upon the
exercise of all such  warrants are being  registered  in this  offering.  50,000
warrants  are  exercisable  at a price of $6.50 per share of Common  Stock until
September  1, 1999;  105,000  warrants are  exercisable  at a price of $9.60 per
share of Common Stock until July 31, 2000; and 66,853  warrants are  exercisable
at a price of $20.52  per share of  Common  Stock  until  March  11,  2001.  The
exercise  price of the  Warrants is subject to  proportional  adjustment  in the
event  that  the  Company   undertakes  a  stock  split,   stock  dividend,   or
recapitalization.

        8% Convertible Debentures

        In July  1995,  the  Company  issued  and  sold in a  private  placement
offering, 8% convertible debentures due July 31, 1997 in the aggregate principal
amount of $12,000,000.  Such debentures are convertible into Common Stock at the
option of the holders  thereof at a  conversion  price that is the lesser of (i)
$8.00  or (ii)  85% of the  



                                       14
<PAGE>
<PAGE>
   

market  value  of the  Common  Stock  on the  date  of  conversion,  subject  to
adjustment  under  certain   circumstances.  As  of  May  24,  1996  convertible
debentures  in the  aggregate  principal  amount  of  $2,850,000,  plus  accrued
interest from July 1995, remained outstanding.
    

        The Company may require the  conversion  of the  convertible  debentures
commencing  October 15, 1995 through  July 30, 1997 at a conversion  price which
varies  and is based upon the  market  price of the common  stock on the date of
conversion.  The Company also has the right to redeem any convertible  debenture
after it has received a notice of conversion with respect to such debenture. The
redemption  price  is the  greater  of 115%  of the  principal  and the  accrued
interest  on  the  redeemed  debenture  or an  amount  which  is  based  on  the
appreciation of the common stock from the date of issuance of the debentures.

        Stock Options
   

        The  Company  has issued  options to  purchase  shares of the  Company's
common stock,  restricted  stock,  and/or other stock-based  performance  awards
under  the 1995  Non-Employee  Directors'  Incentive  Plan,  the 1992  Long-Term
Incentive Plan, the 1992 Non-Employee Directors' Stock Option Plan, and the 1986
Stock  Option  Plan. At May 24, 1996, an aggregate of 1,752,623 options had been
granted and were  outstanding  under these plans with  exercise  prices  between
$5.44 and $17.75 per share of Common Stock.
    

        The Company may grant additional options outside the Plans in connection
with its efforts to hire or retain consultants and others. At December 31, 1995,
the  Compensation  Committee  has been  authorized  by the Board of Directors to
grant  options  outside of the Plans for an  additional  7,918  shares of common
stock,  substantially  all of which may be  exercisable at prices below the fair
value of the common stock on the date of grant.


                                  LEGAL OPINION

        The validity of the shares of Common Stock being offered  hereby will be
passed upon for the Company by Proskauer Rose Goetz & Mendelsohn  LLP, New York,
New York.


                                     EXPERTS

        The financial  statements of Celgene Corporation as of December 31, 1995
and 1994, and for each of the years in the three-year  period ended December 31,
1995,  have  been  incorporated  by  reference  herein  and in the  Registration
Statement  in reliance  upon the report of KPMG Peat  Marwick  LLP,  independent
certified public  accountants,  incorporated by reference  herein,  and upon the
authority of said firm as experts in accounting and auditing.

        The report of KPMG Peat  Marwick  LLP  covering  the  December  31, 1995
financial  statements  refers to the adoption of the provisions of the Financial
Accounting  Standards  Board's Statement of Financial  Accounting  Standards No.
115,  "Accounting  for  Certain  Investments  in Debt  and  Equity  Securities,"
effective January 1, 1994.


                                       15
<PAGE>
<PAGE>






                                3,137,825 SHARES


                               CELGENE CORPORATION



                                  COMMON STOCK

                                   PROSPECTUS

   


                                  MAY 30, 1996

    


<PAGE>
<PAGE>




                                     PART II

                     INFORMATION NOT REQUIRED IN PROSPECTUS


ITEM 14.       OTHER EXPENSES OF ISSUANCE AND DISTRIBUTION.

        An estimate of the fees and expenses of issuance and distribution (other
than discounts and commissions) of the Common Stock offered hereby (all of which
will be paid by the Company) is as follows:

<TABLE>
<S>                                                                     <C>
     SEC registration fee ........................................      $ 15,622
     NASD listing fee ............................................        17,500
     Printing and engraving expenses .............................        10,000
     Legal fees and expenses .....................................        20,000
     Accounting fees and expenses ................................        12,000
     Miscellaneous expenses ......................................        13,000
                                                                        --------
            Total.................................................      $ 88,122
                                                                        ========
</TABLE>





ITEM 15.       INDEMNIFICATION OF DIRECTORS AND OFFICERS.

        The General  Corporation Law of the State of Delaware  ("DGCL")  permits
the Company and its stockholders to limit  directors'  exposure to liability for
certain breaches of the directors' fiduciary duty, either in a suit on behalf of
the Company or in an action by stockholders of the Company.

        The  Certificate  of   Incorporation  of  the  Company  (the  "Charter")
eliminates  the  liability  of  directors  to  stockholders  or the  Company for
monetary damages arising out of the directors' breach of their fiduciary duty of
care.  The Charter  also  authorizes  the Company to  indemnify  its  directors,
officers,  incorporators,  employees,  and agents with respect to certain costs,
expenses, and amounts incurred in connection with an action, suit, or proceeding
by reason of the fact that such  person  was  serving  as a  director,  officer,
incorporator,  employee,  or agent of the  Company.  In  addition,  the  Charter
permits the Company to provide additional indemnification rights to its officers
and directors and to indemnify  them to the greatest  extent  possible under the
DGCL. The Company has entered into  indemnification  agreements with each of its
officers and directors and intends to enter into indemnification agreements with
each of its future  officers  and  directors.  Pursuant to such  indemnification
agreements,  the Company has agreed to  indemnify  its  officers  and  directors
against certain liabilities,  including  liabilities arising out of the offering
made by this  Registration  Statement.  The Selling  Stockholders have agreed to
indemnify  officers,  directors and  controlling  persons of the Company against
certain liabilities,  including  liabilities arising out of the offering made by
this Registration Statement, under certain circumstances.

        The  Company  maintains  a standard  form of  officers'  and  directors'
liability insurance policy which provides coverage to the officers and directors
of the Company for certain liabilities,  including certain liabilities which may
arise out of this Registration Statement.

                                      II-1

<PAGE>
<PAGE>




ITEM 16.       EXHIBITS.

The exhibits  listed in the Exhibit Index as filed as part of this  Registration
Statement.

(a)  Exhibits

Exhibit
Number              Description
- -------             -----------
   
5.1  -- Opinion of Proskauer Rose Goetz & Mendelsohn LLP (previously filed).
    

23.1 -- Consent of KPMG Peat Marwick LLP.

23.2 -- Consent  of  Proskauer  Rose Goetz &  Mendelsohn  LLP  (incorporated  by
        reference to Exhibit 5.1).

   
24.1 -- Power of Attorney (previously filed).

    


                                      II-2

<PAGE>
<PAGE>



ITEM 17.       UNDERTAKINGS.

The undersigned Registrant hereby undertakes:

(1)     To file,  during any period in which  offers or sales are being made,  a
        post-effective  amendment to this Registration Statement: (i) to include
        any prospectus  required by Section 10(a)(3) of the Securities Act; (ii)
        to  reflect  in the  prospectus  any facts or events  arising  after the
        effective  date  of the  Registration  Statement  (or  the  most  recent
        post-effective   amendment  thereof)  which,   individually  or  in  the
        aggregate,  represent a fundamental  change in the information set forth
        in  the  Registration  Statement.  Notwithstanding  the  foregoing,  any
        increase  or  decrease  in volume of  securities  offered  (if the total
        dollar  value of  securities  offered  would not  exceed  that which was
        registered)  and any deviation from the low or high end of the estimated
        maximum  offering range may be reflected in the form of prospectus filed
        with the Commission  pursuant to Rule 424(b) (Section 230.424(b) of this
        chapter) if, in the aggregate, the changes in volume and price represent
        no more than a 20% change in the maximum  aggregate  offering  price set
        forth in the  "Calculation of  Registration  Fee" table in the effective
        registration  statement;  and (iii) to include any material  information
        with respect to the plan of distribution not previously disclosed in the
        Registration Statement or any material change to such information in the
        Registration  Statement;  provided,  however,  that  (i) and (ii) do not
        apply if the Registration  Statement is on Form S-3 or Form S-8, and the
        information required to be included in a post-effective amendment by (i)
        and (ii) is contained in periodic reports filed with or furnished to the
        Commission by the Registrant  pursuant to Section 13 or Section 15(d) of
        the Exchange Act that are  incorporated by reference in the Registration
        Statement.

(2)     That, for the purpose of determining  any liability under the Securities
        Act,  each  such  post-effective  amendment  shall be deemed to be a new
        registration  statement relating to the securities offered therein,  and
        the offering of such  securities  at that time shall be deemed to be the
        initial bona fide offering thereof.

(3)     To remove from  registration by means of a post-effective  amendment any
        of  the  securities   being   registered  which  remain  unsold  at  the
        termination of the offering.

        Insofar as indemnification  for liabilities arising under the Securities
Act may be  permitted to  directors,  officers  and  controlling  persons of the
Registrant pursuant to the foregoing  provisions,  or otherwise,  the Registrant
has been advised that in the opinion of the Securities  and Exchange  Commission
such indemnification is against public policy as expressed in the Securities Act
and is, therefore,  unenforceable. In the event that a claim for indemnification
against such  liabilities  (other than the payment by the Registrant of expenses
incurred or paid by a director,  officer or controlling person of the Registrant
in the successful defense of any action, suit or proceeding) is asserted by such
director,  officer or controlling person in connection with the securities being
registered, the Registrant will, unless in the opinion of its counsel the matter
has been  settled by  controlling  precedent,  submit to a court of  appropriate
jurisdiction the question whether such  indemnification  by it is against public
policy as  expressed  in the  Securities  Act and will be  governed by the final
adjudication of such issue.

        The  undersigned  Registrant  hereby  undertakes  that,  for purposes of
determining  any  liability  under  the  Securities  Act,  each  filing  of  the
Registrant's  annual  report  pursuant to Section  13(a) or Section 15(d) of the
Exchange Act that is  incorporated  by reference in the  Registration  Statement
shall be deemed to be a new  registration  statement  relating to the securities
offered  therein,  and the  offering  of such  securities  at that time shall be
deemed to be the initial bona fide offering thereof.

                                      II-3

<PAGE>
<PAGE>

   

                                   SIGNATURES

        Pursuant  to  the  requirements  of the  Securities  Act  of  1933,  the
Registrant certifies that it has reasonable grounds to believe that it meets all
of  the  requirements  for filing on Form S-3 and has duly caused this Amendment
No. 1 to Registration Statement to be signed on its behalf by  the  undersigned,
thereunto  duly  authorized,  in  the  city  of  Warren,  State of New Jersey on
May 29, 1996.

                                                     CELGENE CORPORATION


                                                     By: /s/ John W. Jackson
                                                        ------------------------
                                                     John W. Jackson
                                                     Chairman of the Board
                                                     and Chief Executive Officer


        Pursuant to the requirements of the Securities Act, this Amendment No. 1
to Registration Statement  has been signed below by the persons whose signatures
appear below, which  persons  have  signed  such  Registration  Statement in the
capacities indicated:

<TABLE>
<CAPTION>
Signature                                Title                         Date
- ---------                                -----                         ----
<S>                           <C>                                  <C>
/s/ John W. Jackson           Chairman of the Board and Chief      May 29, 1996
- ---------------------------   Executive Officer
John W. Jackson

         *                    Director                             May 29, 1996
- ---------------------------
Sol J. Barer

         *                    Director                             May 29, 1996
- ---------------------------
Frank T. Cary

         *                    Director                             May 29, 1996
- ---------------------------
Arthur Hull Hayes, Jr.

         *                    Director                             May 29, 1996
- ---------------------------
Richard C. E. Morgan

         *                    Director                             May 29, 1996
- ---------------------------
Walter L. Robb

         *                    Director                             May 29, 1996
- ---------------------------
Lee J. Schroeder

/s/ Sanford Kaston            Controller (Chief Accounting         May 29, 1996
- ---------------------------   Officer)
Sanford Kaston 

*By John W. Jackson
 as Attorney-in-fact
 /s/ John W. Jackson
 -------------------
 John W. Jackson

</TABLE>

    

<PAGE>
<PAGE>




                                INDEX TO EXHIBITS

   
5   -- Opinion of Proskauer Rose Goetz & Mendelsohn LLP (previously filed).
    

23.1-- Consent of KPMG Peat Marwick LLP.

23.2-- Consent  of  Proskauer  Rose  Goetz &  Mendelsohn  LLP  (incorporated  by
       reference to Exhibit 5.1)
   

24.1-- Power of Attorney (previously filed).
    

                                      II-5


                           STATEMENT OF DIFFERENCES
                           -------------------------
       The trademark symbol shall be expressed as 'tm'

   

    



<PAGE>




<PAGE>

                                                                    EXHIBIT 23.1





                          INDEPENDENT AUDITORS' CONSENT




The Board of Directors and Stockholders
Celgene Corporation:


        We consent to incorporation  by reference in the Registration  Statement
on Form S-3 of Celgene Corporation of our report dated February 17, 1996, except
as to Note 12, which is as of March 13, 1996,  relating to the balance sheets of
Celgene Corporation as of December 31, 1995 and 1994, and the related statements
of operations, stockholders' equity, and cash flows for each of the years in the
three-year  period ended December 31, 1995, which report appears in the December
31, 1995 Annual Report on Form 10-K of Celgene  Corporation and to the reference
to our firm under the heading "Experts" in the prospectus.

        Our report also refers to the  adoption of the  provisions  of Financial
Accounting  Standards  Board's Statement of Financial  Accounting  Standards No.
115,  "Accounting  for  Certain  Investments  in Debt  and  Equity  Securities,"
effective January 1, 1994.




                                                       /s/ KPMG PEAT MARWICK LLP


   

Short Hills, New Jersey
May 29, 1996
    


<PAGE>



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