CELGENE CORP /DE/
8-K, 1996-03-13
INDUSTRIAL ORGANIC CHEMICALS
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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                  --------------------------------------------


                                    FORM 8-K

                  --------------------------------------------



                                 CURRENT REPORT
                     PURSUANT TO SECTION 13 OR 15(d) OF THE
                         SECURITIES EXCHANGE ACT OF 1934


<TABLE>
<S>                                                            <C>
              MARCH 13, 1996                                           0-16132
Date of Report (Date of earliest event reported)                Commission File Number



                               CELGENE CORPORATION
             (Exact name of registrant as specified in its charter)



                 Delaware                                           22-2711928
(State or other jurisdiction of incorporation or         (I.R.S. Employer Identification Number)
                organization)           

</TABLE>


                               7 Powder Horn Drive
                            Warren, New Jersey 07059
  ---------------------------------------------------------------------------

               (Address of Principal Executive Offices) (Zip Code)




                                 (908) 271-1001
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              (Registrant's telephone number, including area code)




- --------------------------------------------------------------------------------
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Item 5. Other Events.

               On March 13, 1996,  Celgene  Corporation (the "Company") issued a
press release announcing that it had completed a $25  million  private placement
of Series A Convertible  Preferred  Stock,  par value $.01 per share.

               The  shares  of  Series  A   Convertible   Preferred   Stock  are
convertible  into  shares  of  Celgene  common  stock,  in  one-third increments
commencing on May 11, June 10 and July 10, 1996, at a conversion price per share
of common stock equal, generally, to the lesser of (i) $18.81, or  (ii)  90%  of
the average closing price per share of common stock  for the seven trading  days
immediately prior to the date of conversion.
 
               This description is a summary and is qualified in its entirety by
reference to  the press release, the  form of Certificate  of  Designation,  and
the form of Registration Rights Agreement  entered into  with the  investors  in
the  private placement, all of which are filed as exhibits hereto and are hereby
incorporated by reference.



Item 7. Financial Statements, Pro Forma Financial Information and Exhibits.

        (a)    not applicable

        (b)    not applicable

        (c)    Exhibits

         4.1   Form of  Amended  and  Restated  Certificate  of  Designation  of
               Series A  Convertible Preferred Stock, par  value  $.01,  of  the
               Company.

        10.1   Form of Registration Rights Agreement

        99     Press Release, dated March 13, 1996.



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                                   SIGNATURES


        Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.


Date: March 13, 1996                CELGENE CORPORATION



                                    By:   /s/ John W. Jackson
                                          ---------------------------
                                    Name:   John W. Jackson
                                    Title:  Chairman of the Board and
                                              Chief Executive Officer

                                        3

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                                  EXHIBIT INDEX


<TABLE>
<CAPTION>

    Exhibit                                 Description                                  Page
- -------------     --------------------------------------------------------------    -------------
<S>               <C>                                                               <C>
      4.1         Form of Amended and Restated  Certificate  of  Designation  of
                  Series A Convertible Preferred Stock, par value  $.01,  of the
                  Company.

      10.1        Form of Registration Rights Agreement

       99         Press Release, dated March 13, 1996.
================================================================================

</TABLE>

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                               CELGENE CORPORATION

                              AMENDED AND RESTATED

                           CERTIFICATE OF DESIGNATION

                                       OF

                              SERIES A CONVERTIBLE

                                 PREFERRED STOCK

        (Pursuant to Section 151 of the Delaware General Corporation Law)

                   We, John W. Jackson and Sanford  Kaston,  the Chairman of the
Board and Chief Executive Officer and the Assistant Secretary,  respectively, of
Celgene Corporation,  a Delaware corporation,  in accordance with the provisions
of Section 103 of the Delaware General Corporation Law do hereby certify that:

               1.  The  name  of  the   corporation   (hereinafter   called  the
"Corporation") is CELGENE CORPORATION, a corporation duly organized and existing
under the laws of the State of Delaware.

               2. The Certificate of Incorporation  (as amended)  authorizes the
issuance of 5,000,000  shares of Preferred Stock of a par value of $.01 each and
expressly  vests in the Board of  Directors  of the  Corporation  the  authority
provided therein to issue any or all of said shares in one or more series and by
resolution or resolutions to establish the designation,  number, full or limited
voting  powers,  or the  denial  of voting  powers,  preferences  and  relative,
participating,  optional,  and  other  special  rights  and the  qualifications,
limitations,  restrictions,  and other  distinguishing  characteristics  of each
series to be issued.

               3. A  Certificate  of  Designation  setting  forth the rights and
privileges with respect to the Series A Convertible  Preferred  Stock,  $.01 par
value per share, of the Corporation and designating Four Hundred Twenty (420) of
the 5  Million  (5,000,000)  authorized  shares of  Preferred  Stock as Series A
Convertible  Preferred  Stock,  $.01 par value  per  share,  was filed  with the
Secretary  of State of the State of Delaware on March 6, 1996.  This Amended and
Restated  Certificate  of  Designation  amends and restates the  Certificate  of
Designation that was filed on March 6, 1996.

               4.  The   following  is  a  true  and  correct  copy  of  certain
resolutions  duly adopted by the Board of Directors of the  Corporation on March
11, 1996, which  constituted all necessary action on the part of the Company for
adoption of such resolutions.


                                        1



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               RESOLVED,  that Five  Hundred  and Twenty  (520) of the 5 Million
(5,000,000)  authorized  shares of Preferred Stock of the  Corporation  shall be
designated  Series A Convertible  Preferred Stock, $.01 par value per share, and
shall possess the rights and privileges set forth below:

               Section 1.  Designation  and  Amount.  The shares of such  series
shall be  designated as "Series A  Convertible  Preferred  Stock" (the "Series A
Convertible Preferred Stock") and the number of shares constituting the Series A
Convertible  Preferred  Stock (the "Shares") shall be 520; such number of shares
may be increased or decreased by resolution of the Board of Directors; provided,
that no  decrease  shall  reduce the number of Shares to a number  less than the
number of shares then outstanding.


               Section 2. Rank. The Series A Convertible  Preferred  Stock shall
rank:  (i) prior to all of the  Corporation's  Common Stock,  par value $.01 per
share  ("Common  Stock");  (ii) prior to any class or series of capital stock of
the Corporation  hereafter created  specifically  ranking by its terms junior to
the Series A Convertible  Preferred Stock (collectively,  with the Common Stock,
"Junior Securities");  (iii) on parity with any class or series of capital stock
of the Corporation hereafter created specifically ranking by its terms on parity
with the Series A Convertible  Preferred  Stock ("Parity  Securities")  and (iv)
junior  to any class or series of  capital  stock of the  Corporation  hereafter
created  specifically  ranking by its terms  senior to the Series A  Convertible
Preferred  Stock  ("Senior  Securities");  in each case as to  distributions  of
assets upon liquidation,  dissolution or winding up of the Corporation,  whether
voluntary or involuntary (all such distributions  being referred to collectively
as "Distributions");

               Section 3.  Dividends.  The Series A Convertible  Preferred Stock
will bear no dividends,  and the holders of the Series A  Convertible  Preferred
Stock  shall not be entitled to receive  dividends  on the Series A  Convertible
Preferred Stock.

               Section 4. Liquidation Preference.

               (a) In the event of any liquidation, dissolution or winding up of
the Corporation,  either  voluntary or involuntary ("an Event"),  the holders of
Shares  shall be entitled to receive,  immediately  after any  distributions  to
Senior  Securities  and prior and in  preference to any  distribution  to Junior
Securities but in parity with any distribution to Parity  Securities,  an amount
per  share  equal to the sum of (i)  $50,000  for each  outstanding  Share  (the
"Original  Series  A Issue  Price")  and  (ii) an  amount  equal  to 4.9% of the
Original Series A Issue Price per annum for the period that has passed since the
date of issuance of any Series A Convertible  Preferred Stock (such amount being
referred to herein as the  "Accretion").  If upon the  occurrence of such Event,
the  assets  and funds  thus  distributed  among  the  holders  of the  Series A
Convertible  Preferred  Stock and Parity  Securities  shall be  insufficient  to
permit the payment to such holders of the full  preferential  amounts due to the
holders of the Series A Convertible  Preferred Stock and the Parity  Securities,
respectively,  then the  entire  assets  and  funds of the  Corporation


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legally available for distribution shall be distributed among the holders of the
Series A Convertible Preferred Stock and the Parity Securities,  pro rata, based
on the  respective  liquidation  amounts to which  each such  series of stock is
entitled   by  the   Corporation's   Certificate   of   Incorporation   and  any
Certificate(s) of Designation.

               (b)  Upon  the  completion  of  the   distribution   required  by
subsection 4(a), if assets remain in this Corporation, they shall be distributed
to holders of Junior Securities in accordance with the Corporation's Certificate
of Incorporation including any duly adopted Certificate(s) of Designation.

               (c) A consolidation or merger of the Corporation with or into any
other corporation or corporations,  or a sale,  conveyance or disposition of all
or substantially all of the assets of the Corporation or the effectuation by the
Corporation  of a transaction  or series of related  transactions  in which more
than 50% of the voting  power of the  Corporation  is disposed  of, shall not be
deemed to be a liquidation, dissolution or winding up within the meaning of this
Section 4, but shall instead be treated pursuant to Section 5(f)(ii) hereof.

               Section 5.  Conversion.

The record  Holders of this  Series A  Convertible  Preferred  Stock  shall have
conversion rights as follows (the "Conversion Rights"):

               (a)  Right  to  Convert.  The  record  holder  of  the  Series  A
Convertible  Preferred Stock shall be entitled, as set forth below, and, subject
to the Company's right of redemption set forth in Section 6 and the restrictions
on  conversion  set forth in Section  5(b) below,  to convert the Shares held by
such holder  into that  number of  fully-paid  and  nonassessable  shares of the
Common Stock at the  Conversion  Rate as set forth below.  The minimum number of
Shares that may be  converted is the lesser of (i) Two Shares or (ii) all of the
Holder's remaining Shares. The rate at which Shares may be converted into shares
of Common  Stock is  hereinafter  referred  to as the  "Conversion  Rate" and is
computed as follows:

Number  of  shares  of  Common  Stock  issued  upon  conversion  of one share of
Preferred Stock = Principal Conversion Rate + Accretion Conversion Rate, where

"Principal Conversion Rate" =                  Issue Price
                                             ----------------
                                             Conversion Price

and "Accretion Conversion Rate =     (.049)(N/365)(Issue Price)
                                     --------------------------
                                     Accretion Conversion Price

where

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           N = the number of days between (i) the date that,  in connection with
           the  consummation of the initial purchase of the Preferred Stock from
           the  Company,  the escrow  agent  first had in its  possession  funds
           representing   full  payment  for  the  Preferred   Stock  for  which
           conversion is being elected, and (ii) the Date of Conversion;

           Issue  Price = the  Original  Series A Issue  Price,  as  defined  in
           Section 4(a);

           Accretion  Conversion  Price equals the average Closing Price for the
           Common Stock as that term is defined below,  for the 30 calendar days
           prior to the Date of Conversion; and

           Conversion  Price = the lesser of (x) $18.81 (the  "Fixed  Conversion
           Price")(which  equals  110% of $17.1,  which is the  average  closing
           price for the seven (7) trading days ending on February 29, 1996), or
           (y) 90% of the average  Closing Price, as that term is defined below,
           of the  Company's  Common  Stock  for  the  seven  (7)  trading  days
           immediately  preceding the Date of Conversion.  For purposes  hereof,
           the  term  "Closing  Price"  shall  mean  the  closing  price  of the
           Company's  Common Stock as reported by NASDAQ (or, if not reported by
           NASDAQ, as reported by such other exchange or market where traded).

        (b)  Restrictions  on  Conversion.  No shares  of  Series A  Convertible
Preferred  Stock may be  converted  prior to 60 days after the Last  Closing (as
defined  in  the   Subscription   Agreement).   Thereafter,   (subject   to  the
effectiveness of the S-3  Registration  Statement as defined in the Subscription
Agreement)  each  Holder of Series A  Convertible  Preferred  Stock may  convert
one-third of his shares of Series A Convertible  Preferred Stock on or after the
60th day after the Last Closing,  an  additional  one-third on or after the 90th
day after the Last Closing,  and all additional  remaining  Series A Convertible
Preferred Stock on or after the 120th day after the Last Closing.

        (c) Mechanics of  Conversion.  In order to convert  Series A Convertible
Preferred Stock into shares of Common Stock,  the holder shall (i) fax a copy of
the fully executed  notice of conversion in the form attached hereto ("Notice of
Conversion")  to the Company at the office of the Company and to American  Stock
Transfer & Trust  Company (the  "Exchange  Agent") that he elects to convert the
same,  which notice shall  specify the number of shares of Series A  Convertible
Preferred  Stock  to be  converted  and  shall  contain  a  calculation  of  the
Conversion  Rate (together with a copy of the first page of each  certificate to
be  converted)  prior to Midnight,  New York City time (the  "Conversion  Notice
Deadline") on the Date of Conversion  specified on the Notice of Conversion  and
(ii) surrender the original certificate or certificates therefor, duly endorsed,
and the original  Notice of  Conversion,  no later than  Midnight (New York City
Time) the next business day, to a common  courier for overnight  delivery or (if
overseas)  2-day  delivery  to the  Exchange  Agent.  The  Company  shall not be
obligated to issue  certificates  evidencing the shares


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of Common Stock  issuable upon such  conversion  unless either the  certificates
evidencing  such  Series A  Convertible  Preferred  Stock are  delivered  to the
Exchange Agent as provided above, or the Holder notifies the Exchange Agent that
such  certificates  have been lost, stolen or destroyed and such Holder provides
such  indemnity as is reasonably  acceptable to the Company with respect to such
lost,  stolen  or  destroyed  certificate.  In the case of a  dispute  as to the
calculation of the Conversion  Rate, the Company's  calculation  shall be deemed
conclusive  absent manifest error. No fractional shares of Common Stock shall be
issued upon conversion of this Series A Convertible  Preferred Stock. In lieu of
any  fractional  share to which the Holder  would  otherwise  be  entitled,  the
Company shall round up to the nearest whole share.

        The Company  shall issue and deliver or cause to be issued and delivered
within three (3)  business  days after  delivery to the  Exchange  Agent of such
certificates,  or after the holder has furnished  such  indemnity such holder of
Series A Convertible  Preferred  Stock at the address of the Holder on the books
of the Company, a certificate or certificates for the number of shares of Common
Stock to which the Holder  shall be entitled as provided in Section  5(a) above.
The date on which conversion  occurs (the "Date of Conversion")  shall be deemed
to be the date set forth in such  Notice of  Conversion,  provided  (i) that the
advance  copy of the  Notice  of  Conversion  is  faxed to the  Company  and the
Exchange  Agent before  midnight,  New York City time, on the Date of Conversion
and (ii)  that the  stock  certificates  (the  "Preferred  Stock  Certificates")
representing  the  Series A  Convertible  Preferred  Stock to be  converted  are
received by the Exchange  Agent within five (5) business  days  thereafter.  The
person or persons  entitled to receive the shares of Common Stock  issuable upon
such  conversion  shall be treated  for all  purposes  as the  record  holder or
holders of such shares of Common Stock on such date.  If the  original  Series A
Convertible Preferred Stock Certificates to be converted are not received by the
Exchange  Agent or the Company  within five (5) business  days after the Date of
Conversion,  the Company may, at its option,  treat the Notice of  Conversion as
null and void.

        (d) Reservation of Stock Issuable Upon Conversion.  The Company shall at
all times reserve and keep available out of its  authorized but unissued  shares
of Common  Stock,  solely for the purpose of  effecting  the  conversion  of the
Series A Convertible  Preferred Stock, such number of its shares of Common Stock
as shall from time to time be  sufficient  to effect the  conversion of all then
outstanding  shares of Series A Convertible  Preferred Stock; and if at any time
the  number of  authorized  but  unissued  shares of Common  Stock  shall not be
sufficient to effect the conversion of all then  outstanding  shares of Series A
Convertible  Preferred Stock, the Company will take such corporate action as may
be necessary to increase its authorized  but unissued  shares of Common Stock to
such number of shares as shall be sufficient for such purpose.

        (e) Automatic  Conversion.  Each share of Series A Convertible Preferred
Stock  outstanding  two years  from the Date of the Last  Closing  automatically
shall be converted into Common Stock on such date at the  Conversion  Price then
in effect  and two years


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from the Date of the Last Closing  shall be deemed the Date of  Conversion  with
respect to such Shares then  outstanding  provided  that,  if such date is not a
business day, the next following business day shall be the operative date.

        (f)    Adjustment to Fixed Conversion Price.

               In computing the Fixed  Conversion  Price for purposes of Section
5(a):

               (i)  If,  prior  to  the  conversion  of  all  of  the  Series  A
Convertible Preferred Stock, the number of outstanding shares of Common Stock is
adjusted by a stock split stock  dividend,  or other  similar  event,  the Fixed
Conversion Price shall be proportionately adjusted.

               (ii) If,  prior to the  conversion  of all  Series A  Convertible
Preferred Stock, there shall be any merger,  consolidation,  exchange of shares,
recapitalization,  reorganization,  or other similar event, as a result of which
shares of Common Stock shall be changed  into the same or a different  number of
shares of the same or another  class or classes  of stock or  securities  of the
Company or another  entity,  then the Holders of Series A Convertible  Preferred
Stock shall thereafter have the right to purchase and receive upon conversion of
Series A  Convertible  Preferred  Stock,  upon the  basis and upon the terms and
conditions  specified  herein  and  in  lieu  of  the  shares  of  Common  Stock
immediately  theretofore  issuable upon conversion,  such shares of stock and/or
securities  as may be issued or payable  with  respect to or in exchange for the
number of  shares  of  Common  Stock  immediately  theretofore  purchasable  and
receivable  upon the conversion of Series A Convertible  Preferred Stock held by
such  Holders  had the Holders  converted  their  Series A  Preferred  to Common
immediately   prior  to  such   merger,   consolidation,   exchange  of  shares,
recapitalization or reorganization,  and in any such case appropriate provisions
shall be made with  respect to the rights and  interests  of the  Holders of the
Series A  Convertible  Preferred  Stock to the end  that the  provisions  hereof
(including,   without  limitation,   provisions  for  adjustment  of  the  Fixed
Conversion  Price and of the number of shares  issuable  upon  conversion of the
Series A Convertible Preferred Stock) shall thereafter be applicable,  as nearly
as may be  practicable  in  relation  to  any  shares  of  stock  or  securities
thereafter be deliverable upon the conversion of Series A Convertible  Preferred
Stock. The Company shall not effect any transaction described in this subsection
5(f) unless the  resulting  successor or  acquiring  entity (if not the Company)
assumes by written  instrument  the  obligation to deliver to the Holders of the
Series A Convertible  Preferred Stock such shares of stock and/or securities as,
in  accordance  with the  foregoing  provisions,  the  Holders  of the  Series A
Convertible Preferred Stock may be entitled to purchase.

               (iii) If any  adjustment  under this  Section 5(f) would create a
fractional  share of Common  Stock or a right to acquire a  fractional  share of
Common Stock, such fractional share (on an aggregate basis) shall be disregarded
and the  number of shares of Common  Stock  issuable  upon  conversion  shall be
rounded to the next higher number of shares.


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               Section 6. Redemption by Company; Lock Up.

        (a)  Company's  Right to  Redeem or Lock Up  Conversion  in the Event of
Conversion.

               (i) Redemption Upon Receipt of Notice of Conversion. In the event
the average  Closing Price of the  Company's  Common Stock on the NASDAQ for the
seven (7) trading days immediately  preceding the Date of Conversion shall be at
or less than the Fixed  Conversion  Price,  the Company shall have the right, in
its sole discretion,  upon receipt of a Notice of Conversion pursuant to Section
5, to  redeem  in whole or in part any  Series  A  Convertible  Preferred  Stock
submitted for conversion, immediately prior to conversion. If the Company elects
to  redeem  some,  but not all,  of the  Series A  Convertible  Preferred  Stock
submitted  for  conversion,  the  Company  shall  redeem from among the Series A
Convertible Preferred Stock submitted by the various shareholders for conversion
on the applicable  date, a pro-rata  amount from each  shareholder so submitting
Series A Convertible Preferred Stock for conversion.

        In the case of a redemption under this Section  6(a)(i),  the redemption
        price shall  equal the sum of the  Principal  Redemption  Price plus the
        Accretion, where:

               Principal Redemption Price =

                          Issue Price x Closing Price on Date of Conversion
                          -------------------------------------------------
                                           Conversion Price

        In the event of redemption,  the Accretion is payable,  at the Company's
option,  in cash or Common Stock. If the Accretion is paid in Common Stock,  the
number of shares for such payment shall be  calculated  in  accordance  with the
following formula:

                                    Accretion
                                    ---------
                           Accretion Conversion Price


               where "N," "Issue Price," "Closing Price",  "Accretion Conversion
               Price" and  "Conversion  Price"  have the  meanings  set forth in
               Section 5, and  "Accretion"  has the meaning set forth in Section
               4.

               (ii)  Redemption  or Lockup Below Soft Floor Price.  In the event
the  Closing  Price per share  shall be at or less than  $11.50 (the "Soft Floor
Price"),  for each of the five (5) trading days preceding the date of submission
of a Notice of Conversion by a Holder,  the Company shall have the right, in its
sole discretion,  upon receipt of such Notice of Conversion  pursuant to Section
5, to elect, in lieu of conversion, either (A) or (B), as follows:

                      A. The Company may elect to declare such  conversion  null
                      and



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                      void,  and declare  that no  conversion  of any  Preferred
                      Stock that is  included in the Notice of  Conversion  (the
                      "Affected  Preferred  Stock")  shall be permitted  for the
                      subsequent  ninety  (90) day  period  (the "90 Day Lock Up
                      Period").  In the event the Company declares a 90 Day Lock
                      Up Period,  the  Company  shall  issue  within 10 business
                      days,  to the  Holder  of  the  Affected  Preferred  Stock
                      warrants ("90 Day Lock Up Warrants"),  to purchase  Common
                      Stock of the Company, as follows:

                                    Terms of 90 Day Lock Up Warrant

                             - the 90 Day  Lock Up  Warrant  shall  entitle  the
                             holder  to  purchase  a number  of shares of common
                             stock  equal  to 10% of the  number  of  shares  of
                             Common  Stock  that  would  have been  issued  upon
                             conversion of the Affected  Preferred  Stock at the
                             Soft Floor Price.

                             - the  strike  price of the 90 Day Lock Up  Warrant
                             shall equal the Soft Floor Price.

                             - the term of the 90 Day Lock Up  Warrant  shall be
                             two (2) years.

                      The Company may, in its  discretion,  offer ("180 Day Lock
                      Up Offer") to provide  another  warrant  ("180 Day Lock Up
                      Warrant"),  in addition to the 90 Day Lock Up Warrant,  to
                      purchase  Common  Stock of the  Company,  to the Holder of
                      Affected  Preferred  Stock in exchange  for such  Holder's
                      agreement  to  forebear  from   converting   its  Affected
                      Preferred  Stock for an  additional  90 days beyond the 90
                      Day Lockup Period (a "180 Day Lockup Period"). The Holder,
                      in its  discretion,  may accept or reject the 180 Day Lock
                      Up Offer. The Company shall issue to the Holder, within 10
                      business days of Holder's written  acceptance of a 180 Day
                      Lock Up  Offer,  a 180 Day Lock Up  Warrant,  the terms of
                      which shall be equivalent to the terms of a 90 Day Lock Up
                      Warrant.

                      After  any 90 Day Lock Up Period or 180 Day Lock Up Period
                      (as  applicable),  the Investor shall again be entitled to
                      convert the Affected Preferred Stock pursuant to the terms
                      of  Section  5  above,   without  any   further   lock  up
                      restrictions.

                      B.  Redeem  such  Affected  Preferred  Stock  pursuant  to
                      Section 6(a)(i).


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               (iii)  Mechanics  of  Redemption  or  Lock  Up.  Any  shareholder
considering  submitting  Preferred  Stock  for  conversion  at such  time as the
Company's  right of redemption  under  Section  6(a)(i) or lock up under Section
6(a)(ii) is or may be in effect may provide  notice to the Company by facsimile,
of his  possible  desire to convert a  specified  number of Shares,  and ask the
Company to  determine  whether or not the Company  would  exercise  its right of
redemption or lock up if the Shares were submitted for  conversion.  The Company
shall  respond  within  two (2)  business  days of the date of  receipt  of that
notice,  and state whether it would redeem or lock up the Shares, in whole or in
part, or allow conversion into Common Stock without redemption or lock up, which
election will be applicable to conversion by such  shareholder  of the number of
Shares specified in his notice within the next five business days after the date
of the Company's response.  Failure of the Company to respond within the two (2)
business  day period shall be deemed an election by the Company not to redeem or
lock up the Shares covered by that notice if submitted for conversion within the
next five  business  days.  If the holder  does not  provide  advance  notice of
intention  to convert as  contemplated  in this section  (iii),  the Company may
effect redemption or lock up of Shares submitted for conversion by giving notice
of its  election  to redeem  or lock up, by  facsimile  within 2  business  days
following  receipt  of a Notice  of  Conversion  from a  Holder,  with a copy by
overnight or 2-day courier, to (A) the Holder of Series A Convertible  Preferred
Stock  submitted  for  conversion  at the address and  facsimile  number of such
Holder  appearing  in the  Company's  register  for  the  Series  A  Convertible
Preferred Stock and (B) the Exchange Agent.  Such notice shall indicate  whether
the  Company  will  redeem  or lock up all or part of the  Series A  Convertible
Preferred Stock submitted for conversion.

The  Company  shall not be  entitled  to  exercise  its  right to redeem  shares
submitted  for  conversion  under this  Section  6(a) unless it has (x) the full
amount  of the  redemption  price,  in  cash,  available  in a  demand  or other
immediately  available account in a bank or similar financial institution or (y)
immediately  available credit  facilities,  in the full amount of the redemption
price, with a bank or similar  financial  institution on the date the redemption
notice is sent to Holders.

        (b)  Company's  Right to Call  Redemption  if the Price of the Company's
Common Stock Is Greater Than the Fixed Strike Price.  The Company shall have the
right to redeem the Series A Convertible  Preferred Stock on the following terms
and conditions:

                      (i) at any time after nine (9) months  following  the Last
               Closing  Date,  if the  average  closing  price of the  Company's
               Common Stock for the seven (7) trading days immediately preceding
               the Notice  Date (as  defined  below) is  greater  than the Fixed
               Conversion  Price,  the  Company  may,  in its  discretion,  give
               written notice that it intends,  at least thirty (30) but no more
               than forty five (45)  business  days from the date of such notice
               ("Notice  Date") to redeem  the  Series A  Convertible  Preferred
               Stock at the  redemption  price  listed in 6(b)(iii)  below.  The
               Company  may elect to




                                       9
<PAGE>
 
<PAGE>

               redeem some,  but not all, of the Series A Convertible  Preferred
               Stock,  but in no event less than $1,500,000 per  redemption.  If
               the Company  elects to redeem some,  but not all, of the Series A
               Convertible  Preferred Stock, the Company shall redeem a pro-rata
               amount from among all the Series A  Convertible  Preferred  Stock
               holders.  The holders of the Preferred Stock shall have the right
               to convert their Preferred Stock until the redemption date.

                      (ii)  Mechanics of  Redemption.  The Company  shall effect
               each such  redemption by giving notice of its election to redeem,
               by facsimile with a copy by overnight or 2-day  courier,  no less
               than 30 business days prior to the intended redemption date. Such
               redemption  notice shall indicate whether the Company will redeem
               all or part of the  Series A  Convertible  Preferred  Stock,  the
               effective date of the  redemption  and the applicable  redemption
               price.  The  Company  shall not be entitled to send any notice of
               redemption and begin the redemption  procedure  unless it has (x)
               the full amount of the redemption price, in cash,  available in a
               demand  or  other  immediately  available  account  in a bank  or
               similar financial institution or (y) immediately available credit
               facilities,  in the full amount of the redemption  price,  with a
               bank or similar financial  institution on the date the redemption
               notice  is  sent  to  shareholders.  If the  Company  has met the
               requirements  of the  preceding  sentence,  and a Holder  has not
               submitted his Series A Convertible Preferred Stock for redemption
               as required by this  Section  6(c) by the  redemption  date,  the
               Company may pay the redemption price described in (iii) below and
               cancel the Series A  Convertible  Preferred  Stock subject to the
               redemption   notice,  and  such  redeemed  Series  A  Convertible
               Preferred Stock shall be of no further validity, force or effect.

                      (iii)  Redemption  Price.  In  the  case  of  a redemption
               under  this  Section 6(b),  the  redemption  price  per share  of
               Series  A  Convertible Preferred Stock shall be as follows:


<TABLE>
<CAPTION>
                         Redemption Price                 Elapsed Time since Last
Closing                  ----------------                 -----------------------
- -------
<S>                   <C>                                   <C>
                      130% of Stated Value                       9  months  and  1  day  -  12
months
                      125% of Stated Value                       12  months  and  1  day  - 18
months
                      120% of Stated Value                       18  months  and  1  day  - 24
months
</TABLE>

               For purposes of this  paragraph,  the "Stated  Value" shall equal
               the Original Series A Issue Price plus the Accretion  (calculated
               as of the effective date of such redemption).


                                       10
<PAGE>
 
<PAGE>





        (c) Payment of Redemption  Price.  The redemption  price for redemptions
under either  Section 6(a) or 6(b) above shall be paid to the Holder of Series A
Convertible   Preferred   Stock  redeemed  within  5  business  days  after  the
redemption;  provided,  however,  that the  Company  shall not be  obligated  to
deliver any portion of such  redemption  price  unless  either the  certificates
evidencing  the Series A Convertible  Preferred  Stock redeemed are delivered to
the Exchange  Agent,  or the Holder  notifies the Company or the Exchange  Agent
that such  certificates  have been lost,  stolen or  destroyed  and  executes an
agreement  satisfactory  to the Company to  indemnify  the Company from any loss
incurred by it in connection with such certificates.

Section 7.  Voting  Rights.  The holders of the Series A  Convertible  Preferred
Stock have no voting rights except as required by the General Corporation Law of
the State of Delaware.

Section 8. Protective  Provision.  So long as shares of Series A Preferred Stock
are outstanding,  the Company shall not alter or change the rights,  preferences
or privileges of the shares of Series A Convertible  Preferred Stock in a manner
not  contemplated  hereby so as to affect  adversely  the  Series A  Convertible
Preferred Stock.

Section 9.  Status of Redeemed or  Converted  Stock.  In the event any shares of
Series A Convertible  Preferred Stock shall be redeemed or converted pursuant to
Section 5 or Section 6 hereof,  the shares so  converted  or  redeemed  shall be
canceled,  shall return to the status of authorized but unissued Preferred Stock
of no designated  series, and shall not be issuable by the Corporation as Series
A Convertible Preferred Stock.

               FURTHER RESOLVED,  that the statements contained in the foregoing
resolutions  creating and  designating  the said Series A Convertible  Preferred
Stock and  fixing  the  number,  powers,  preferences  and  relative,  optional,
participating,  and other special  rights and the  qualifications,  limitations,
restrictions,  and other distinguishing  characteristics thereof shall, upon the
effective date of said series,  be deemed to be included in and be a part of the
Certificate of  Incorporation  of the Corporation  pursuant to the provisions of
the General Corporation Law of the State of Delaware.

               FURTHER  RESOLVED,  that the officers of the  Corporation be, and
each acting  individually hereby is, authorized and directed to take all actions
necessary  and  advisable  to effect the  purpose  and  intent of the  foregoing
resolutions.


                                       11
<PAGE>
 
<PAGE>





        IN WITNESS WHEREOF,  Celgene  Corporation has caused this certificate to
be signed by John P.  Jackson,  its  Chairman  of the Board and Chief  Executive
Officer, and attested by Sanford Kaston, its Assistant Secretary,  this 11th day
of March, 1996.


                            CELGENE CORPORATION


                            By ____________________________
                               John W. Jackson
                               Chairman of the Board and Chief Executive Officer

Attest:


By __________________________
      Sanford Kaston
      Assistant Secretary

               Each of the  undersigned,  the  Chairman  of the  Board and Chief
Executive Officer and Assistant Secretary, respectively, of Celgene Corporation,
a Delaware  corporation,  declares under penalty of perjury that the matters set
forth in this certificate are true and correct of his own knowledge.

               Executed at Warren, New Jersey on March __, 1996.



                               ____________________________
                               John W. Jackson
                               Chairman of the Board and Chief Executive Officer


                               ____________________________
                               Sanford Kaston
                               Assistant Secretary



                                       12

<PAGE>
 



 
<PAGE>
                          REGISTRATION RIGHTS AGREEMENT

        THIS REGISTRATION  RIGHTS AGREEMENT  ("Agreement") is entered into as of
___________,  1996, by and among  CELGENE  CORPORATION,  a Delaware  corporation
("Company"),  Swartz  Investments,  LLC,  a Georgia  limited  liability  company
("Swartz  Investments")  and the  subscribers  ("Subscribers")  to the Company's
offering  ("Offering")  of up to $15 million of Series A  Convertible  Preferred
Stock (the "Preferred Stock") pursuant to the Subscription Agreement between the
Company and the Subscribers ("Subscription Agreement").

        1. Definitions. For purposes of this Agreement:

        (a) The term "register",  "registered,"  and  "registration"  refer to a
registration  effected  by  preparing  and filing a  registration  statement  or
similar document in compliance with the Securities Act of 1933 (the "Act"),  and
the declaration or ordering of effectiveness of such  registration  statement or
document;

        (b) The term "Registrable Securities" means the Common Stock issuable or
issued upon (i)  conversion  of the  Preferred  Stock issued to Investors in the
Offering,  (ii)  exercise  of the Lockup  Warrants,  and (iii)  exercise  of the
Warrant(s);

        (c) The number of shares of "Registrable  Securities  then  outstanding"
shall be  determined  by the  number of shares of Common  Stock  which have been
issued or are issuable upon  conversion  of the Preferred  Stock and exercise of
the Warrants and Lock Up Warrants at the time of such determination;

        (d) The term  "Holder"  means any  person  owning or having the right to
acquire Registrable Securities or any permitted assignee thereof;

        (e) The term "Warrants" means the warrants granted to Swartz Investments
or to  persons  designated  by Swartz  Investments  in  connection  with i) this
Offering and ii) the offering by the Company,  through Swartz Investments,  Inc.
of the Company's 8% Convertible Debentures Due July 31, 1997;

        (f) The term "Lockup  Warrants"  means the "90 Day Lockup  Warrants" and
the "180 Day Lockup  Warrants",  as those  terms are defined in  Certificate  Of
Designation of Series A Convertible Preferred Stock of Celgene Corporation; and

        (g)  The  term   "Initiating   Holders"  means  holders  of  Registrable
Securities  obtained  or  obtainable  upon  conversion  of at least four hundred
(400) shares of Preferred Stock.

        2. Required Registration.

        (a) Within 30 days after the Last Closing of the Offering (as defined in
the  Subscription  Agreement),  but in no event  sooner  than April 10, 1996 the
Company shall

                                       1


<PAGE>
 
<PAGE>

file a registration statement  ("Registration  Statement") on Form S-3 (or other
suitable  form,  at the  Company's  discretion  but  subject  to the  reasonable
approval of the  Investors),  covering  the resale of all shares of  Registrable
Securities then outstanding.

        (b) The Registration  Statement shall be done as a "shelf"  registration
statement under Rule 415, and shall be maintained  effective until completion of
the distribution described therein or such time as  all  Registrable  Securities
covered thereby can be immediately sold without any limitation  on  volume.  The
Company shall use its best efforts to have the  Registration  Statement declared
effective  within 90 days after the Last Closing (as defined in the Subscription
Agreement)  (the date which is 90 days after the Last Closing herein referred to
as the "Due Date").

        (c) If the Registration  Statement is not declared  effective by the Due
Date,  the Company must continue to use its best efforts to obtain a declaration
of  effectiveness  and shall pay the Investors an amount equal to one and a half
percent (1 1/2%) per month of the  aggregate  amount of Preferred  Stock sold in
the Offering,  compounded  monthly,  and accruing  daily,  for the first six (6)
months and one percent (1%)  thereafter,  payable in common stock,  which common
stock  shall also be deemed  "Registrable  Securities"  for the  purpose of this
Agreement.  Provided, however, that such additional amounts shall not be payable
for so long as any delay in the  effectiveness of the Registration  Statement is
due,  directly  to causes  that are beyond the control of the Company, including
but not limited to acts of God, acts or omissions of the Agent or the Investors,
acts or omissions of  any  government  or  regulatory  body  (whether  civil  or
military)  that  result  in  a  delay  of  the  declaration  by  the  SEC of the
effectiveness of registration  statements generally,  fires, explosions, floods,
earthquakes  or  other  natural or man-made  disasters,  epidemics, wars, riots,
civil  disturbances,  sabotage,  strikes, lockouts, labor difficulties involving
third  parties,  loss  of  electrical  or  other  power,  or  telecommunications
equipment or line failures.

        3. Demand Registration.

        (a) If the  Registration  Statement  described in Section 2 above is not
effective by the Due Date,  Initiating Holders may notify the Company in writing
and demand that the Company file a registration  statement  under the Securities
Act (a "Demand  Registration  Statement") covering the resale of the Registrable
Securities then outstanding  held by such Holders.  Upon receipt of such notice,
the Company shall, within ten (10) days thereafter,  give written notice of such
request to all Holders and shall, subject to the limitations of subsection 3(b),
as soon as  practicable,  and in any event  within 60 days after the  receipt of
such  request,  include in the Demand  Registration  Statement  all  Registrable
Securities which the Holders request, by notice given to the Company within (10)
days of receipt of the Company's notice.

        (b) If the  Initiating  Holders  intend to  distribute  the  Registrable
Securities  covered by their request by means of an underwriting,  they shall so
advise the Company as a part of their  request  made  pursuant to this Section 3
and the Company shall include such information in the written notice referred to
in subsection  3(a). In such event, the

                                       2


<PAGE>
 
<PAGE>

right  of any  other  Holder  to  include  his  Registrable  Securities  in such
registration  shall be  conditioned  upon such  Holder's  participation  in such
underwriting  and the inclusion of such Holder's  Registrable  Securities in the
underwriting  (unless otherwise mutually agreed by a majority in interest of the
Initiating  Holders and such Holder) to the extent provided herein.  All Holders
proposing  to  distribute  their  securities  through  such  underwriting  shall
(together  with the  Company  as  provided  in  subsection  6(f))  enter into an
underwriting  agreement in customary form with the  underwriter or  underwriters
selected  for such  underwriting  by a majority in  interest  of the  Initiating
Holders,  and  reasonably  acceptable  to the  Company.  The Holder  will not be
required  to make  any  representation  other  than as to its  ownership  of the
Registrable Securities and its intended method of distribution.

        (c) The  Company is  obligated  to effect  only one demand  registration
pursuant to Section 3 of this Agreement.  The  Company  agrees  to  include  all
Registrable  Securities  held  by  all  Holders in such  Registration  Statement
without cutback or reduction. In the event the Company  breaches its  obligation
of the preceding sentence,  any Holders of the Registrable Securities which were
not included in such Registration Statement shall be entitled to such  a  second
demand  registration for such excluded securities and  the  Company  shall  keep
such registration statement effective as required by Section 6.

        The Company is not obligated to effect a demand  registration under this
Section 3 if in the opinion of counsel to the Company  reasonably  acceptable to
the  person or persons  from whom  written  request  for  registration  has been
received  (and  satisfactory  to the  Company's  transfer  agent to  permit  the
transfer)  that  registration  under the Act is not required  for the  immediate
transfer  of all of the  Registrable  Securities  pursuant  to Rule 144 or other
applicable  provision.  Such  opinion  shall be  addressed  to the Holder at the
Holder's Request.

        4. Piggyback  Registration.  If the Registration  Statement described in
Section  2 is not  effective  by  the  Due  Date,  and no  demand  for a  Demand
Registration  Statement has been made pursuant to Section 3, and if (but without
any  obligation to do so) the Company  proposes to register  (including for this
purpose a registration  effected by the Company for shareholders  other than the
Holders) any of its Common Stock under the Securities Act in connection with the
public  offering of such  securities  solely for cash (other than a registration
relating  solely for the sale of securities to  participants  in a Company stock
plan or a registration on Form S-4  promulgated  under the Securities Act or any
successor or similar form  registering  stock issuable upon a  reclassification,
upon a business  combination  involving  an  exchange of  securities  or upon an
exchange  offer for  securities  of the issuer or another  entity),  the Company
shall,  at  such  time,  promptly  give  each  Holder  written  notice  of  such
registration (a "Piggyback Registration Statement"). Upon the written request of
each  Holder  given by fax within ten (10) days after  mailing of such notice by
the Company,  which request shall state the intended  method of  disposition  of
such shares by such Holder,  the Company shall cause to be registered  under the
Securities  Act all of the  Registrable  Securities  that each such  Holder  has
requested  to be  registered.  The rights of Holders  pursuant to this Section 4
will be limited to one Piggyback  Registration  Statement and the Company is not
obligated to effect a demand registration under this Section 4 if in the opinion
of counsel to the

                                       3


<PAGE>
 
<PAGE>

Company reasonably acceptable to the person or persons from whom written request
for registration has been received (and  satisfactory to the Company's  transfer
agent to permit the transfer)  that  registration  under the Act is not required
for the immediate transfer of all of the Registrable Securities pursuant to Rule
144 or other applicable provision.


        5. Limitation on Obligations to Register.

        (a) In the case of a Piggyback  Registration on an  underwritten  public
offering by the Company, if the managing  underwriter  determines and advises in
writing that the  inclusion  in the  registration  statement of all  Registrable
Shares proposed to be included would interfere with the successful  marketing of
the securities proposed to be registered by the Company, then the number of such
Registrable  Shares  to be  included  in the  registration  statement  shall  be
allocated  among all Holders who had requested  Piggyback  Registration,  in the
proportion  that the  number of  Registrable  Shares  which  each  such  Holder,
including  Swartz  Investments,  seeks to register  bears to the total number of
Registrable  Shares  sought to be  included  by all  Holders,  including  Swartz
Investments;  provided  that  in  no  event  shall  the  number  of  Registrable
Securities  be less than 20% of the total  number  of  shares  included  in such
registration.

        (b)  Notwithstanding  anything to the contrary herein, the Company shall
have the right (i) to defer the initial  filing or request for  acceleration  of
effectiveness  of any Demand  Registration  Statement or Piggyback  Registration
Statement  or (ii) after  effectiveness,  to suspend  effectiveness  of any such
registration statement, if, in the good faith judgment of the board of directors
of the  Company  and upon the advice of counsel  to the  Company,  such delay in
filing  or  requesting  acceleration  of  effectiveness  or such  suspension  of
effectiveness  is  necessary in light of the  existence  of material  non-public
information  (financial or otherwise) concerning the Company disclosure of which
at the time is not, in the opinion of the board of directors of the Company upon
the advice of counsel,  (A) otherwise  required and (B) in the best interests of
the  Company;  provided  however  that the  Company  will not  delay or  suspend
effectiveness  of such  registration for more than three months from the date of
the demand,  unless it is then  engaged in an  acquisition  that would make such
registration  impracticable,  in  which  case it will use its  best  efforts  to
eliminate such impracticability as soon as possible.

                                        4


<PAGE>
 
<PAGE>



        6.  Obligations  of the Company. Whenever required under this Agreement
to effect the Registration of any Registrable  Securities,  the  Company  shall,
as  expeditiously  as  reasonably  possible,

        (a)  in  the  event  that  the  number   of  shares  available  under  a
registration   statement   filed  pursuant  to   Section   2   or   3  above  is
insufficient  to  cover  all  of  the  Registrable  Securities then outstanding,
based  upon  the  prior  day's  Closing  Price  (as  defined in  the Certificate
of  Designation)   of  the  Series  A  Convertible  Preferred Stock, the Company
shall   amend   that  registration   statement,  or  file  a  new   registration
statement,  or both, so as to cover all shares of  Registrable  Securities  then
outstanding.  The Company shall use its best efforts to effect such amendment or
new  registration  within 90 days of the date the  registration  statement  file
under  Section 2 or 3 is  insufficient  to cover all the  shares of  Registrable
Securities  then  outstanding.  Failure to effect an  amendment  or have the new
registration  statement declared effective within that 90 day period will result
in the Company's obligation to pay the additional amounts stated in Section 2(c)
to the Holders of Shares then outstanding, provided that such additional amounts
shall not be payable for any day for which the number of shares of Common  Stock
available under the Registration Statement, is sufficient,  based upon the prior
day's Closing Price to cover all of the Registrable Securities then outstanding.

        (b) Prepare and file with the SEC a registration  statement with respect
to  such  Registrable  Securities  and  use  its  best  efforts  to  cause  such
registration statement to become effective.

        (c) Prepare and file with the SEC such  amendments  and  supplements  to
such registration statement and  the  prospectus  used  in  connection with such
registration  statement as may be necessary to comply with the provisions of the
Act  with  respect  to  the  disposition  of  all  securities  covered  by  such
registration statement.

        (d) With respect to any Demand Registration Statement,  use best efforts
to keep such registration  statement effective until the later of 60 days  after
all shares of the Preferred Stock have  been  converted  and  all  Warrants  and
Lock-up Warrants have been exercised.


        (e)  Furnish to the  Holders  such  numbers  of copies of a  prospectus,
including a preliminary  prospectus,  in conformity with the requirements of the
Securities Act, and such other documents as they may reasonably request in order
to facilitate the disposition of Registrable Securities owned by them.

        (f) Use its best efforts to register and qualify the securities  covered
by such  registration  statement under such other securities or Blue Sky laws of
such  jurisdictions  as shall be  reasonably  requested  by the  Holders  of the
Registrable Securities covered by such registration statement, provided that the
Company shall not be required in connection  therewith or as a condition thereto
to qualify to do business or to file a general  consent to service of process in
any such states or jurisdictions.

        (g) In the event of any  underwritten  public  offering,  enter into and

                                       5


<PAGE>
 
<PAGE>

perform its obligations under an underwriting  agreement, in usual and customary
form, with the managing underwriter of such offering.  Each Holder participating
in such  underwriting  shall also enter into and perform its  obligations  under
such an agreement.

        (h) Furnish,  at the request of any Holder  requesting  registration  of
Registrable  Securities  pursuant  to this  Agreement,  on the  date  that  such
Registrable  Securities are delivered to the underwriters for sale in connection
with a registration  pursuant to this  Agreement,  if such  securities are being
sold through  underwriters,  or, if such  securities  are not being sold through
underwriters,  on the date that the registration  statement with respect to such
securities  becomes effective,  (i) an opinion,  dated such date, of the outside
counsel of recognized Standing (or reasonably acceptable to Holder) representing
the   Company   for  the  purposes   of   such   registration,   in   form   and
substance as is customarily  given to  underwriters  in an  underwritten  public
offering,  addressed to the underwriters,  if any, and to the Holders requesting
registration  of Registrable  Securities and (ii) a letter dated such date, from
the  independent  certified  public  accountants  of the  Company,  in form  and
substance as is customarily given by independent certified public accountants to
underwriters in an underwritten public offering,  addressed to the underwriters,
if any, and to the Holders requesting registration of Registrable Securities.

        (i) As  promptly  as  practicable  after  becoming  aware of such event,
notify  each  Investor  of the  happening  of any event of which the Company has
knowledge,  as a result of which the  prospectus  included  in the  Registration
Statement, as then in effect, includes an untrue statement of a material fact or
omits to state a material  fact  required to be stated  therein or  necessary to
make the statements therein, in light of the circumstances under which they were
made, not misleading,  and use its best efforts promptly to prepare a supplement
or amendment to the  Registration  Statement to correct such untrue statement or
omission, and deliver a number of copies of such supplement or amendment to each
Investor as such Investor may reasonably request.

        (j) Provide  Holders with written notice of the date that a registration
statement  registering  the resale of the  Registrable  Securities  is  declared
effective by the Securities and Exchange Commission ("SEC").

        (k) Provide Holders and their representatives the opportunity to conduct
a reasonable due diligence  inquiry of Company's  pertinent  financial and other
records and make  available its officers,  directors and employees for questions
regarding  such  information  as it  relates  to  information  contained  in the
registration statement.

        (l) Provide Holders and their  representatives the opportunity to review
the  registration  statement and all amendments  thereto a reasonable  period of
time prior to their  filing with the SEC and refrain from filing any document in
a form to which Holders reasonably object.

        7.  Furnish  Information.  It  shall  be a  condition  precedent  to the
obligations  of the Company to take any action  pursuant to this  Agreement with
regard to each selling  Holder that such selling  Holders  shall  furnish to the
Company such

                                       6


<PAGE>
 
<PAGE>

information regarding themselves,  the Registrable  Securities held by them, and
the intended  method of disposition  of such  securities as shall be required to
effect the  registration  of their  Registrable  Securities or to determine that
registration is not required pursuant to Rule 144 or other applicable  provision
of the Act.

        8. Expenses of Demand Registration. All expenses other than underwriting
discounts and commissions incurred in connection with registrations,  filings or
qualifications  pursuant to Sections 2 and 3, including (without limitation) all
registration, filing and qualification fees, printers' and accounting fees, fees
and disbursements of counsel for the Company,  and including the reasonable fees
and disbursements incurred of only one counsel for the selling Holders, shall be
borne  by  the  Company;  provided,  however,  that the  Company  shall  not  be
required to pay for any expenses of any  registration  proceeding begun pursuant
to  Section 3 if the  registration  request  is  subsequently  withdrawn  at the
request  of the  Holders  of a  majority  of the  Registrable  Securities  to be
registered (in which case all Holders who had requested such registration  shall
bear such  expenses);  provided  further,  however,  that if at the time of such
withdrawal,  the  Holders  have  learned  of a  material  adverse  change in the
condition,  business, or prospects of the Company from that known to the Holders
at the time of their request,  then the Holders shall not be required to pay any
of such expenses and shall retain their rights pursuant to Section 3.

        9. Expenses of Company Registration.  The Company shall bear and pay all
expenses incurred in connection with any  registration,  filing or qualification
of Registrable Securities with respect to the registration pursuant to Section 4
for each Holder,  including (without  limitation) all registration,  filing, and
qualification  fees,  printers and  accounting  fees  relating or  apportionable
thereto (and including the reasonable  fees and  disbursements  incurred of only
one  counsel  for  the  selling  Holders   selected  by  them),   but  excluding
underwriting discounts and commissions relating to Registrable Securities.

        10.  Indemnification.  In  the  event  any  Registrable  Securities  are
included in a registration statement under this Agreement:

        (a) To the extent  permitted by law, the Company will indemnify and hold
harmless each Holder, the officers and directors of each Holder, any underwriter
(as defined in the Act) for such Holder and each  person,  if any,  who controls
such  Holder or  underwriter  within the  meaning  of the Act or the  Securities
Exchange Act of 1934, as amended (the "1934 Act"),  against any losses,  claims,
damages,  or  liabilities  (joint or several)  to which they may become  subject
under the Act,  the 1934 Act or other  federal  or state  law,  insofar  as such
losses,  claims,  damages,  or liabilities (or actions in respect thereof) arise
out  of or  are  based  upon  any  of the  following  statements,  omissions  or
violations (collectively a "Violation"):  (i) any untrue statement of a material
fact  contained  in  such  registration  statement,  including  any  preliminary
prospectus  or  final  prospectus   contained   therein  or  any  amendments  or
supplements thereto, (ii) the omission to state therein a material fact required
to  be  stated  therein,  or  necessary  to  make  the  statements  therein  not
misleading,  or (iii) any violation by the Company of the Act, the 1934 Act, any

                                       7

<PAGE>
 
<PAGE>

state  securities law or any rule or regulation  promulgated  under the Act, the
1934 Act or any state  securities  law; and the Company will reimburse each such
Holder, officer or director,  underwriter or controlling person for any legal or
other expenses  reasonably  incurred by them in connection with investigating or
defending any such loss, claim, damage, liability, or action; provided, however,
that the indemnity  agreement contained in this subsection 10(a) shall not apply
to amounts paid in settlement of any such loss,  claim,  damage,  liability,  or
action if such settlement is effected  without the consent of the Company (which
consent shall not be unreasonably withheld),  nor shall the Company be liable in
any such case for any such  loss,  claim,  damage,  liability,  or action to the
extent  that it  arises  out of or is based  upon a  Violation  which  occurs in
reliance upon and in conformity with written information furnished expressly for
use in connection with such registration by any such Holder, officer,  director,
underwriter or controlling person.

        (b) To the extent  permitted by law, each selling Holder,  severally and
not  jointly,  will  indemnify  and  hold  harmless  the  Company,  each  of its
directors, each of its officers who have signed the registration statement, each
person,  if any,  who  controls  the Company  within the meaning of the Act, any
underwriter  and any  other  Holder  selling  securities  in  such  registration
statement or any of its  directors  or officers or any person who controls  such
Holder, against any losses,  claims,  damages, or liabilities (joint or several)
to which the  Company or any such  director,  officer,  controlling  person,  or
underwriter or controlling person, or other such Holder or director,  officer or
controlling  person may  become  subject,  under the Act,  the 1934 Act or other
federal or state law, insofar as such losses,  claims,  damages,  or liabilities
(or actions in respect thereto) arise out of or are based upon any Violation, in
each case to the extent (and only to the extent) that such  Violation  occurs in
reliance  upon and in  conformity  with  written  information  furnished by such
Holder  expressly for use in connection  with such  registration;  and each such
Holder will  reimburse any legal or other  expenses  reasonably  incurred by the
Company and any such  director,  officer,  controlling  person,  underwriter  or
controlling person, other Holder,  officer,  director,  or controlling person in
connection  with  investigating  or  defending  any such  loss,  claim,  damage,
liability, or action; provided,  however, that the indemnity agreement contained
in this  subsection  10(b) shall not apply to amounts paid in  settlement of any
such loss,  claim,  damage,  liability or action if such  settlement is effected
without the  consent of the  Holder,  which  consent  shall not be  unreasonably
withheld;  provided, that, in no event shall any indemnity under this subsection
10(b) exceed the gross proceeds from the offering received by such Holder.

        (c) Promptly after receipt by an indemnified party under this Section 10
of notice of the commencement of any action (including any governmental action),
such indemnified party will, if a claim in respect thereof is to be made against
any indemnifying  party under this Section 10, deliver to the indemnifying party
a written notice of the commencement  thereof and the  indemnifying  party shall
have the right to participate in, and, to the extent the  indemnifying  party so
desires,  jointly with any other indemnifying party similarly noticed, to assume
the defense thereof with counsel mutually satisfactory to the parties; provided,
however,  that an  indemnified  party  shall  have the right to  retain  its own
counsel,  with  the  reasonably  incurred  fees and  expenses  to be paid by the
indemnifying  party, if  representation of such indemnified party by the

                                       8


<PAGE>
 
<PAGE>

counsel retained by the indemnifying  party would be inappropriate due to actual
or potential  conflicting interests between such indemnified party and any other
party  represented  by such counsel in such  proceeding.  The failure to deliver
written  notice  to the  indemnifying  party  within  a  reasonable  time of the
commencement  of any such action,  if  prejudicial to its ability to defend such
action,   shall  relieve  such  indemnifying  party  of  any  liability  to  the
indemnified  party under this Section 10, but the omission so to deliver written
notice to the  indemnifying  party will not relieve it of any liability  that it
may have to any indemnified party otherwise than under this Section 10.

        (d)  In the event that the indemnity provided in  paragraph  (a)  or (b)
of this  Section  10 is  unavailable  to or  insufficient  to hold  harmless  an
indemnified  party for  any reason, the  Company and each  holder of Registrable
Securities agree  to contribute  to the  aggregate claims,  losses, damages  and
liabilities (including legal or other expenses reasonably incurred in connection
with  investigating  or defending  same)  (collectively 'Losses')  to  which the
Company and one or more of the holders of Registrable Securities may be  subject
in  such  proportion as  is appropriate  to  reflect the  relative fault  of the
Company and the  holders in connection  with the statements  or omissions  which
resulted  in such Losses; provided, however, that in no case shall any holder be
responsible for any  amount in excess  of the net  purchase price of  securities
sold  by it under the registration statement. Relative fault shall be determined
by reference to  whether any  alleged untrue  statement or  omission relates  to
information  provided by  the Company  or by  the holders.  The Company  and the
holders agree  that it  would not  be just  and equitable  if contribution  were
determined  by pro rata allocation or any  other method of allocation which does
not  take  account   of  the   equitable  considerations   referred  to   above.
Notwithstanding  the  provisions  of this  paragraph  (d), no  person  guilty of
fraudulent misrepresentation  (within  the  meaning  of  Section  11(f)  of  the
Securities  Act) shall be entitled  to contribution from any  person who was not
guilty of such fraudulent  misrepresentation. For purposes  of this Section  10,
each  person who controls a holder  of Registrable Securities within the meaning
of either the  Securities Act or  the Exchange Act  and each director,  officer,
partner,  employee  and  agent  of  a  holder  shall  have  the  same  rights to
contribution as such holder, and each person who controls the Company within the
meaning of either the Securities  Act or the Exchange  Act and each director  of
the  Company, and each  officer of the  Company who has  signed the registration
statement, shall have the same rights to contribution as the Company, subject in
each case to the applicable terms and conditions of this paragraph (d).


        (e) The  obligations  of the Company and Holders  under this  Section 10
shall survive the redemption and conversion, if any, of the Preferred Stock, the
completion of any offering of Registrable Securities in a registration statement
under this Agreement, and otherwise.


        11. Reports Under Securities Exchange Act of 1934. With a view to making
available to the Holders the benefits of Rule 144 promulgated  under the Act and
any other rule or  regulation of the SEC that may at any time permit a Holder to
sell securities of the Company to the public without  registration,  the Company
agrees to:

        (a) make and keep  public  information  available,  as those  terms  are
understood and defined in SEC Rule 144;

        (b) file with the SEC in a timely manner all reports and other documents
required of the Company under the Act and the 1934 Act; and

        (c)  furnish to any Holder,  so long as the Holder owns any  Registrable
Securities,  forthwith upon request (i) a written  statement by the Company,  if
true, that it has complied with the reporting  requirements of SEC Rule 144, the
Act and the 1934 Act, (ii) a copy of the most recent annual or quarterly  report
of the Company and such other reports and documents so filed by the Company, and
(iii) such other  information  as may be  reasonably  requested  in availing any
Holder of any rule or  regulation  of the SEC which  permits  the selling of any
such securities without registration.

        12.  Amendment of Registration  Rights.  Any provision of this Agreement
may be amended and the observance  thereof may be waived (either generally or in
a particular instance and either retroactively or prospectively),  only with the
written  consent of the Company and the holders of a majority of the Registrable
Securities  provided that the amendment  treats all Holders equally and provided
further  that there can be no material  reduction in a Holder's  rights  without
consent of such Holder. Any amendment or waiver effected in accordance with this
paragraph  shall be  binding  upon each  Holder,  each  future  Holder,  and the
Company.

        13.  Notices.  All notices  required or permitted  under this  Agreement
shall be made in writing signed by the party making the same,  shall specify the
section  under  this  Agreement  pursuant  to which it is  given,  and  shall be
addressed if to (i) the Company at: President,  7 Powder Horn Drive,  Warren, NJ
07059,  Telephone No. (908) 271-

                                       9


<PAGE>
 
<PAGE>

1001,  Telecopy No. (908) 805-3931 and (ii) the Holders at their respective last
address as the party  shall  have  furnished  in writing as a new  address to be
entered on such  register.  Any  notice,  except as  otherwise  provided in this
Agreement,  shall  be made by fax and  shall  be  deemed  given  at the  time of
transmission of the fax.

        14. Termination. This Agreement shall terminate on the date that is five
years from the date of this Agreement; but without prejudice to (i) the parties'
rights and obligations  arising from breaches of this Agreement  occurring prior
to  such  termination,   (ii)  other  indemnification   obligations  under  this
Agreement,  or (iii) the Company's obligation to maintain the effectiveness of a
registration  statement filed prior thereto in accordance with the terms hereof,
and to fulfill its obligations hereunder  in  respect  thereof  until it  is  no
longer required to maintain the effectiveness thereof.

        15.  Assignment.  No  assignment,  transfer  or  delegation,  whether by
operation of law or otherwise, of any rights or obligations under this Agreement
by the  Company or any  Holder,  respectively,  shall be made  without the prior
written  consent of the  majority in  interest  of the  Holders or the  Company,
respectively;  provided  that the  rights of a Holder  may be  transferred  to a
subsequent  holder  of  the  Holder's  Registrable   Securities  (provided  such
transferee  shall  provide  to the  Company,  together  with  or  prior  to such
transferee's  request  to have  such  Registrable  Shares  included  in a Demand
Registration or Piggyback  Registration,  a writing  executed by such transferee
agreeing to be bound as a Holder by the terms of this  Agreement);  and provided
further  that the Company may  transfer  its rights and  obligations  under this
Agreement to a purchaser of all or a substantial  portion of its business if the
obligations of the Company under this  Agreement are assumed in connection  with
such  transfer,  either by merger or other  operation  of law (which may include
without  limitation a transaction  whereby the Registrable  Shares are converted
into securities of the successor in interest) or by specific assumption executed
by the transferee.

        16.  Governing Law. This Agreement shall be governed by and construed in
accordance  with  the  laws of the  State  of  Delaware,  U.S.A.  applicable  to
agreements made in and wholly to be performed in that  jurisdiction,  except for
matters  arising  under the Act or the  Securities  Exchange Act of 1934,  which
matters shall be construed and interpreted in accordance with such laws.

        IN WITNESS  WHEREOF,  the undersigned have executed this Agreement as of
the date first above written.

                                       CELGENE CORPORATION


                                       By: ________________________________
                                             _________________
                                             President


                                    Address:  ___________________

                                       10

<PAGE>
 
<PAGE>



                                              ___________________

                                              ___________________



                                       INVESTOR(S)


                                       ___________________________________
                                       Investor's Name


                                       By:_________________________________
                                               (Signature)


                                    Address:  ___________________

                                              ___________________

                                              ___________________





                                       11

<PAGE>
 




<PAGE>

IMMEDIATE
 
<TABLE>
<S>               <C>
John W. Jackson   Thomas Redington
Chairman & CEO    203/222-7399
908/271-4119      212/926-1733
</TABLE>
 
                CELGENE COMPLETES $25 MILLION PRIVATE PLACEMENT
                -----------------------------------------------
 
     WARREN,  NJ  MAR  13 --  Celgene  Corporation (Nasdaq:  CELG)  announced it
completed a $25 million Regulation D placement of Series A Convertible Preferred
Stock.
 
     Celgene officials  said the  proceeds will  be used  to fund  research  and
development for the company's pharmaceutical programs and for working capital.
 
     Celgene  said the  Series A Convertible  Preferred Stock and  the shares of
common stock issuable  upon its conversion  have not been  registered under  the
Securities  Act of 1933, as amended (the 'Act'),  and may not be offered or sold
absent  registration  under  the  Act  or  an  applicable  exemption  from   the
registration requirements under the Act.  Celgene intends to file a registration
statement covering the resale of the underlying shares of common stock in  April
1996.
 
     Cash  and marketable securities at December 31, 1995, would have been $35.5
million with the inclusion of the net proceeds from the private placement.
 
     Swartz Investments of Atlanta, GA acted as placement agent.
 
     Celgene   Corporation,  headquartered  in   Warren,  NJ,  uses  proprietary
expertise in small molecule chemistry  to service the pharmaceutical and  allied
industries.
 
3/13/96

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