CELGENE CORP /DE/
8-K, 2000-02-22
COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH
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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549


                               _________________

                                    FORM 8-K
                               _________________



                                 CURRENT REPORT
                     PURSUANT TO SECTION 13 OR 15(D) OF THE
                         SECURITIES EXCHANGE ACT OF 1934





        FEBRUARY 17, 2000                            0-16132
- -----------------------------------        --------------------------------
          Date of Report                        Commission File Number
(Date of earliest event reported)



                               CELGENE CORPORATION
             (Exact name of registrant as specified in its charter)



         DELAWARE                                    22-2711928
- -----------------------------------        --------------------------------
  (State or other jurisdiction                    (I.R.S. Employer
of incorporation or organization)               Identification Number)


                               7 Powder Horn Drive
                            Warren, New Jersey 07059
       -------------------------------------------------------------------
               (Address of Principal Executive Offices) (Zip Code)


                                 (732) 271-1001
       -------------------------------------------------------------------
              (Registrant's telephone number, including area code)


________________________________________________________________________________
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<PAGE>




ITEM 5.   OTHER EVENTS.

          On February 17, 2000, Celgene  Corporation (the "Company") amended the
Rights  Agreement,  dated as of  September  16,  1996  between  the  Company and
American  Stock  Transfer  &  Trust  Company,   as  Rights  Agent  (the  "Rights
Agreement"),  changing the initial  exercise price  thereunder  from $100.00 per
Right (as defined in the Rights  Agreement)  to $700.00 per Right and  extending
the Final  Expiration Date (as that term is defined in the Rights  Agreement) to
February 17, 2010.

          Amendment  Number One to the Rights  Agreement  is filed as an exhibit
hereto and is hereby incorporated by reference.

ITEM 7.   FINANCIAL STATEMENTS, PRO FORMA FINANCIAL INFORMATION AND EXHIBITS.

     (a)  not applicable

     (b)  not applicable

     (c)  EXHIBITS

          99   Amendment  Number  One  to  the  Rights  Agreement  dated  as  of
               September 16, 1996 between Celgene Corporation and American Stock
               Transfer & Trust Company, as Rights Agent.




<PAGE>



                                   SIGNATURES

     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.


Date: February 18, 2000                CELGENE CORPORATION



                                       By:   /S/ JOHN W. JACKSON
                                           -------------------------------
                                             Name:  John W. Jackson
                                             Title: Chairman of the Board and
                                                    Chief Executive Officer


<PAGE>



                                  EXHIBIT INDEX



     Exhibit                       Description                            Page
     -------   ------------------------------------------------------     ----

        99     Amendment  Number  One  to  the  Rights  Agreement
               dated as of September 16, 1996 between Celgene
               Corporation and American Stock Transfer & Trust Company,
               as Rights Agent.






                              AMENDMENT NUMBER ONE
                                     TO THE
                 RIGHTS AGREEMENT DATED AS OF SEPTEMBER 16, 1996
                         BETWEEN CELGENE CORPORATION AND
            AMERICAN STOCK TRANSFER & TRUST COMPANY, AS RIGHTS AGENT


Reference is made to the Rights Agreement dated as of September 16, 1996 between
Celgene Corporation and American Stock Transfer & Trust Company, as Rights Agent
(the "Rights  Agreement").  Capitalized terms not otherwise defined herein shall
have the meaning ascribed thereto in the Rights Agreement.

1.   Section  7(a) of the Rights  Agreement  is deleted and  restated to read as
     follows:

          "Section 7. EXERCISE OF RIGHTS;  PURCHASE  PRICE;  EXPIRATION  DATE OF
RIGHTS.  (a) Subject to Section 7(e) hereof,  the registered holder of any Right
Certificate  may  exercise  the Rights  evidenced  thereby  (except as otherwise
provided  herein)  in whole or in part at any time after the  Distribution  Date
upon surrender of the Right  Certificate,  with the form of election to purchase
and the  certificate  on the reverse side thereof duly  executed,  to the Rights
Agent at the principal office or offices of the Rights Agent designated for such
purpose,  together  with payment of the aggregate  Purchase  Price for the total
number of Common  Shares (or other  securities,  as the case may be) as to which
such  surrendered  Rights are exercised,  at or prior to the earliest of (i) the
close of business on February 17, 2010 (the "Final  Expiration  Date"),  or (ii)
the time at which the Rights are  redeemed as provided in Section 23 hereof (the
"Redemption Date")."

2.   Section  7(b) of the Rights  Agreement  is deleted and  restated to read as
     follows:

          "(b) The purchase price (the "Purchase Price") per whole Common Share
at which a holder of Rights may purchase Common Shares or (subject to Section 14
hereof)  fractions  thereof  upon  exercise of such Rights  shall  initially  be
$700.00,  shall be  subject  to  adjustment  from  time to time as  provided  in
Sections 11 and 13(a) hereof,  and shall be payable in accordance with paragraph
(c) below."


                  [REMAINDER OF PAGE INTENTIONALLY LEFT BLANK.]


<PAGE>




Except as amended hereby,  the Rights Agreement shall continue in full force and
effect.

Dated as of February 18, 2000

CELGENE CORPORATION


By: /s/ Robert J. Hugin
    Name: Robert J. Hugin
    Title: Senior Vice President and Chief Financial Officer

Countersigned:

AMERICAN STOCK TRANSFER & TRUST COMPANY



By: /s/ Herbert J. Lemmer
    Name: Herbert J. Lemmer
    Title: Vice President




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