ADVANCED POLYMER SYSTEMS INC /DE/
10-Q, 1997-08-12
PLASTIC MATERIALS, SYNTH RESINS & NONVULCAN ELASTOMERS
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                                    FORM 10-Q

                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


[X]                 Quarterly Report Under Section 13 or 15(d)
                     of the Securities Exchange Act of 1934

                  For the quarterly period ended June 30, 1997


[ ]            Transition  Report  Pursuant to Section 13 or 15(d)
                     of the Securities Exchange Act of 1934

                  For the transition period from _____ to _____


                         Commission file Number 0-16109


                         ADVANCED POLYMER SYSTEMS, INC.
                         ------------------------------
             (Exact name of registrant as specified in its charter)


          Delaware                                          94-2875566
          --------                                          ----------
(State or other jurisdiction of                            (IRS Employer
incorporation or organization)                          Identification No.)


                    3696 Haven Avenue, Redwood City, CA 94063
                    -----------------------------------------
                    (Address of principal executive offices)

                                 (415) 366-2626
                                 --------------
              (Registrant's telephone number, including area code)

Indicate by check mark whether the registrant (1) has filed all reports required
to be filed  by  Section  13 or 15 (d) of the  Securities  Exchange  Act of 1934
during the preceding 12 months (or for such shorter  period that the  registrant
was  required  to file such  reports),  and (2) has been  subject to such filing
requirements for the past 90 days.

Yes  X  No
    ---    ---

At July 31, 1997 the number of outstanding shares of the Company's common stock,
par value $.01, was 18,784,832.

<PAGE>

                                      INDEX





PART I.          FINANCIAL INFORMATION                                 Page No.
                                                                       --------

      ITEM 1.    Financial Statements (unaudited):

                 Condensed Consolidated Balance Sheets                    3
                 June 30, 1997 and December 31, 1996

                 Condensed Consolidated Statements of Operations          4
                 for the three months and six months ended June 30,
                 1997 and 1996

                 Condensed Consolidated Statements of Cash Flows          5
                 for the six months ended June 30, 1997 and 1996

                 Notes to Condensed Consolidated Financial Statements     6


      ITEM 2.    Management's Discussion and Analysis                     9
                 of Financial Condition and Results of Operations


PART II.         OTHER INFORMATION


      ITEM 1.    Legal Proceedings                                        14

      ITEM 4.    Submission of Matters to a Vote of Security Holders      14

      ITEM 6.    Exhibits and Reports on Form 8-K                         14

                 Signatures                                               15


                                        2


<PAGE>

<TABLE>
                              ADVANCED POLYMER SYSTEMS, INC.
                           CONDENSED CONSOLIDATED BALANCE SHEETS
                                        (Unaudited)
<CAPTION>
                                                         June 30, 1997  December 31, 1996
                                                         -------------  -----------------
<S>                                                       <C>             <C>       
ASSETS
Current assets:
    Cash and cash equivalents                             $  7,449,934    $  5,394,509
    Trade accounts receivable, net                           3,259,074       1,666,148
    Inventory                                                2,618,969       2,085,073
    Prepaid expenses and other                                 456,054         328,028
    Assets held for sale                                          --         2,181,004
                                                          ------------    ------------

             Total current assets                           13,784,031      11,654,762

    Property and equipment, net                              4,929,715       4,681,292
    Deferred loan costs, net                                   485,326         616,958
    Prepaid license fees                                       124,316         165,752
    Intangible assets, including goodwill, net               1,568,271       1,265,801
    Other assets                                               147,780          59,603
                                                          ------------    ------------

                                                          $ 21,039,439    $ 18,444,168
                                                          ============    ============

LIABILITIES & SHAREHOLDERS' EQUITY
Current liabilities:
    Accounts payable                                      $    918,249    $  1,543,143
    Accrued expenses                                         2,292,879       1,456,512
    Accrued melanin purchase commitments                     1,800,000       1,800,000
    Accounts payable, Johnson & Johnson                        320,707         814,509
    Deferred revenues                                        2,250,000         750,000
    Current portion - long-term debt                         2,160,655       1,490,779
                                                          ------------    ------------

             Total current liabilities                       9,742,490       7,854,943

Long-term debt                                               4,330,705       5,578,849
                                                          ------------    ------------

             Total liabilities                              14,073,195      13,433,792
                                                          ------------    ------------

Shareholders' equity:
    Common stock and common stock warrants                  78,760,061      76,591,381
    Accumulated deficit                                    (71,793,817)    (71,581,005)
                                                          ------------    ------------

             Total shareholders' equity                      6,966,244       5,010,376
                                                          ------------    ------------

                                                          $ 21,039,439    $ 18,444,168
                                                          ============    ============
<FN>
                                  See accompanying notes.
</FN>
</TABLE>
                                        3


<PAGE>


<TABLE>
                         ADVANCED POLYMER SYSTEMS, INC.

                 CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
                                   (Unaudited)
<CAPTION>
                                        Three Months Ended               Six Months Ended
                                  June 30, 1997    June 30, 1996   June 30, 1997   June 30, 1996
                                  -------------    -------------   -------------   -------------
<S>                                <C>             <C>             <C>             <C>         
Microsponge product
    and technology revenues        $  4,499,516    $  2,057,520    $  8,046,648    $  3,506,265
Sales of consumer products                 --         3,296,000            --         7,000,727
Milestone payment                          --              --         1,500,000            --
                                   ------------    ------------    ------------    ------------

Total revenues                        4,499,516       5,353,520       9,546,648      10,506,992

Cost of sales                         1,952,179       2,989,382       3,443,694       6,294,188

Operating expenses:
Research & development                  900,817         983,843       1,833,291       1,873,799
Selling, marketing & advertising        949,069       2,386,747       2,122,881       4,424,315
General & administration              1,069,705         833,870       1,912,999       1,503,891
                                   ------------    ------------    ------------    ------------

Total operating expenses              2,919,591       4,204,460       5,869,171       7,802,005
                                   ------------    ------------    ------------    ------------

Operating income (loss)                (372,254)     (1,840,322)        233,783      (3,589,201)

Interest income                          80,227          75,012         159,527         113,968

Interest expense                       (268,862)       (313,948)       (540,254)       (613,026)

Other income (expense)                  (70,845)         21,201         (65,867)         10,905
                                   ------------    ------------    ------------    ------------

Net loss                           ($   631,734)   ($ 2,058,057)   ($   212,811)   ($ 4,077,354)
                                   ============    ============    ============    ============

Net loss per common share          ($      0.03)   ($      0.11)   ($      0.01)   ($      0.23)
                                   ============    ============    ============    ============


Weighted average common shares
    outstanding                      18,577,599      18,080,623      18,491,867      17,717,740
                                   ============    ============    ============    ============

<FN>
                             See accompanying notes.
</FN>
</TABLE>

                                        4


<PAGE>

<TABLE>
                         ADVANCED POLYMER SYSTEMS, INC.

                 CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
                 for the six months ended June 30, 1997 and 1996
                                   (Unaudited)
<CAPTION>
                                                        June 30, 1997  June 30, 1996
                                                        -------------  -------------
<S>                                                      <C>            <C>         
Cash flows from operating activities:
Net loss                                                 ($  212,811)   ($4,077,354)
Adjustments to reconcile net loss to net
    cash used in operating activities:
       Depreciation and amortization                         487,413        707,997
       Change in allowance for doubtful accounts                --           (4,106)
       Provision for obsolescence of inventory               120,000           --
       Provision for deferred compensation                   126,757           --
       Changes in operating assets and liabilities:
             Trade accounts receivable                    (1,592,926)    (1,898,532)
             Inventory                                      (653,896)     2,426,175
             Prepaid expenses and other                      (98,026)        96,184
             Deferred loan costs                             131,632         83,731
             Other assets                                   (488,176)        70,881
             Accounts payable and accrued expenses          (342,329)    (2,301,329)
             Deferred revenue                              1,500,000           --
                                                         -----------    -----------

Net cash used in operating activities                     (1,022,362)    (4,896,353)
                                                         -----------    -----------

Cash flows from investing activities:
Purchases of fixed assets                                   (596,872)      (211,547)
Purchase of marketable securities                         (1,596,617)      (512,513)
Maturities and sales of marketable securities              1,596,617        506,374
Proceeds from assets held for sale                         2,181,004           --
                                                         -----------    -----------

Net cash provided from (used in) investing activities      1,584,132       (217,686)
                                                         -----------    -----------

Cash flows from financing activities:
Proceeds from the exercise of common stock options
    and warrants                                           2,071,923      1,561,769
Proceeds from note payable                                      --        1,250,000
Proceeds from long-term debt and warrants                       --          150,000
Repayment of long-term debt                                 (578,268)      (390,103)
Proceeds from private placement, net of offering costs          --        4,903,020
                                                         -----------    -----------

Net cash provided from financing activities                1,493,655      7,474,686
                                                         -----------    -----------

Net increase in cash and cash equivalents                  2,055,425      2,360,647

Cash and cash equivalents, beginning of the
    period                                                 5,394,509      5,172,809
                                                         -----------    -----------

Cash and cash equivalents, end of the period             $ 7,449,934    $ 7,533,456
                                                         ===========    ===========
<FN>
Supplemental disclosure of non-cash investing and financing transactions:

   During the first  quarter of 1996,  the  Company  acquired  all rights to the
     Polytrap(R)  technology from Dow Corning Corporation in exchange for shares
     of Common Stock valued at $1,200,000.

   During the first  quarter of 1996,  the Company paid  Biosource  for the 1995
     purchase  commitment  totalling $600,000 by issuing 94,000 shares of Common
     Stock.

                             See accompanying notes.
</FN>
</TABLE>
                                        5


<PAGE>

                         ADVANCED POLYMER SYSTEMS, INC.

              Notes to Condensed Consolidated Financial Statements
                             June 30, 1997 and 1996
                                   (Unaudited)


(1)    Basis of Presentation

       In the  opinion  of  management,  the  accompanying  unaudited  condensed
       consolidated financial statements contain all adjustments,  consisting of
       normal recurring  adjustments,  necessary to present fairly the financial
       position  of  Advanced  Polymer  Systems,  Inc.  and  subsidiaries  ("the
       Company"  or  "APS")  as of June  30,  1997  and  the  results  of  their
       operations for the three and six months ended June 30, 1997 and 1996, and
       their cash flows for the six months ended June 30, 1997 and 1996.

       These  condensed  consolidated  statements  should be read in conjunction
       with the Company's  audited  consolidated  financial  statements  for the
       years ended December 31, 1996, 1995 and 1994.

       The condensed  consolidated  financial  statements  include the financial
       statements of the Company and its subsidiaries, Premier, Inc. ("Premier")
       and APS Analytical Standards,  Inc. All significant intercompany balances
       and transactions have been eliminated in consolidation.

       Effective January 1997, as part of the Company's long-term strategic plan
       to move away from the direct marketing of consumer products, APS licensed
       its  consumer  products  to  Lander  Company.  The  Company  is no longer
       generating  revenues  from  sales of  these  products,  but is  receiving
       revenues from royalties on product sales and the supply of Microsponge(R)
       systems  incorporated into various  products.  Prior year results include
       the  sales of  consumer  products  and  related  selling,  marketing  and
       distribution expenses.

       The Company  considers  all  short-term  investments  which have original
       maturities of less than three months to be cash equivalents.  Investments
       which have original maturities longer than three months are classified as
       marketable securities in the accompanying balance sheets.

       Certain  reclassifications  have been made to the  prior  year  financial
       statements to conform with the presentation in 1997.


                                        6


<PAGE>

(2)    Common Shares Outstanding and per Share Information


       Common stock outstanding as of June 30, 1997 is as follows:

                                                                Number of Shares
                                                                ----------------
       Common stock outstanding as of December 31, 1996            18,359,744
       Warrants exercised                                             294,314
       Options exercised after December 31, 1996                       91,597
                                                                   ----------
              Total shares                                         18,745,655
                                                                   ==========

       The  number  of shares  used in  calculating  earnings  per share was the
       weighted  average  number of shares of common stock  outstanding.  Common
       stock equivalents were not considered since they were antidilutive.

(3)    New Accounting Standards

       In  February  1997,  the  Financial  Accounting  Standards  Board  issued
       Statement of Financial Accounting Standards No. 128, "Earnings per Share"
       (SFAS 128), which will be effective for financial  statements for periods
       ending  after  December  15,  1997,   including   interim  periods,   and
       establishes  standards for computing and  presenting  earnings per share.
       Earlier  application  is not  permitted.  In its  consolidated  financial
       statements  for the year ending  December 31, 1997, the Company will make
       the required  disclosures  of basic and diluted  earnings per share.  All
       prior period earnings per share data will be restated by the Company upon
       adoption of SFAS 128.

       In June 1997, the Financial  Accounting  Standards Board issued Statement
       of  Financial  Accounting  Standards  No.  130  "Reporting  Comprehensive
       Income" (SFAS 130) which will be effective for financial  statements  for
       periods beginning after December 15, 1997, and establishes  standards for
       reporting  and display of  comprehensive  income and its  components in a
       full set of general purpose financial statements.  Earlier application is
       permitted.  The Company will make the required reporting of comprehensive
       income in its  consolidated  financial  statements  for the first quarter
       ending March 31, 1998.

        In June 1997, the Financial  Accounting Standards Board issued Statement
        of Financial Accounting Standards No. 131 "Disclosures about Segments of
        a Business  Enterprise" (SFAS 131) which will be effective for financial
        statements beginning after December 15, 1997, and establishes  standards
        for disclosures about segments of an enterprise.  Earlier application is
        encouraged.  In its  consolidated  financial  statements  for  the  year
        December 31, 1998, the Company will make the required disclosures.

                                        7
<PAGE>

(4)    Milestone Payment

       In February 1997,  upon receipt of marketing  clearance from the Food and
       Drug  Administration  ("FDA") to market Retin-A(R)  Micro(TM)  (tretinoin
       gel)  0.1%  -  microsphere  for  the  treatment  of  acne,  APS  received
       $3,000,000 from Ortho McNeil Pharmaceutical  Corporation, a subsidiary of
       Johnson  &  Johnson.  One half of the  amount  received  was a  milestone
       payment which was recognized as revenues in the first quarter of 1997 and
       the other half was  prepaid  royalties  which was  recorded  as  deferred
       revenue.

(5)    Inventory

       The major components of inventory are as follows:

                                                June 30, 1997  December 31, 1996
                                                -------------  -----------------
       Raw materials and work-in-process          $  739,485       $  604,852
       Finished goods                              1,879,484        1,480,221
                                                  ----------       ----------
       Total inventory                            $2,618,969       $2,085,073
                                                  ==========       ==========
                                            

                                        8

<PAGE>

Item 2.

           Management's Discussion and Analysis of Financial Condition
                            and Results of Operations
              (all dollar amounts rounded to the nearest thousand)

Results of Operations for the Three Months Ended June 30, 1997 and 1996

Except  for  statements  of  historical   fact,   the   statements   herein  are
forward-looking  and are  subject  to a number of risks and  uncertainties  that
could cause actual results to differ  materially from the statements made. These
include, among others,  uncertainty associated with timely approval,  launch and
acceptance of new products,  establishment of new corporate alliances,  progress
in  research  and  development  programs  and  other  risks  described  below or
identified from time to time in the Company's Securities and Exchange Commission
filings.

The Company's revenues are derived principally from product sales,  license fees
and royalties. The Company is currently manufacturing and selling Microsponge(R)
delivery systems for use by customers in almost 100 different  personal care and
cosmetic  products.  Under  strategic  alliance  arrangements  entered into with
certain  multinational  corporations,  APS  generally  receives an initial  cash
infusion,  future  milestone  payments,  royalties  based on third party product
sales and revenues from the supply of Microsponge systems.

These strategic alliances are intended to provide the Company with the marketing
expertise and/or financial  strength of other  companies.  In this respect,  the
Company's periodic financial results are dependent upon the degree of success of
current  collaborations  and  the  Company's  ability  to  negotiate  acceptable
collaborative agreements in the future.

Microsponge  product and  technology  revenues for the second quarter of 1997 of
$4,500,000  represented an increase of $2,442,000 or 119% over the corresponding
quarter of the prior year.  This  increase was due  primarily to the launches of
new products  incorporating  the  Company's  proprietary  technology  which were
licensed  by three  key  marketing  partners  -  Retin-A(R)  Micro(TM)  by Ortho
Dermatological for which the Company received marketing  clearance from the U.S.
Food and Drug  Administration  (FDA) in February 1997,  ANEW(R) Retinol Recovery
Complex  PM  Treatment  which is  marketed  by  Avon,  Inc.,  and  TxSystems(TM)
AFIRM(TM) retinol formulation which is marketed by Medicis.  Continued growth in
other segments of the Company's business also contributed to the sales increase.

The second quarter of the prior year included  $3,296,000 from sales of consumer
products which are no longer marketed by the Company.

                                        9
<PAGE>

Gross  profit on product  and  technology  revenues  for the second  quarter was
$2,547,000 or 57% compared to $2,364,000 or 44% in the corresponding  quarter of
the prior year due  primarily to increased  sales of higher  margin  proprietary
cosmeceutical products and increased manufacturing volume.

Operating expenses for the second quarter of 1997 decreased by $1,285,000 or 31%
compared to the corresponding  quarter in the prior year. This was due primarily
to the decrease in selling,  marketing and advertising  expense by $1,438,000 to
$949,000 which relates to the fact that the Company no longer  directly  markets
consumer products, thus avoiding the associated advertising and variable selling
expenses. Research and development expense decreased by $83,000 or 8% due mainly
to a reallocation of resources as more products which  incorporate the Company's
technologies  are being  commercialized.  This was partially offset by increased
spending  on  clinical  studies  on  Vitamin K and a new  family of  bioerodible
polymers which are under review by potential partners.

General and  administrative  expense  increased by $236,000 or 28% to $1,070,000
due mainly to certain non-recurring expenses incurred with outside consultants.

The operating  loss for the second  quarter of 1997 of $372,000  represented  an
improvement  of  $1,468,000 or 80% from the  corresponding  quarter of the prior
year.  This was primarily the result of the improvement in gross margins and the
significant reduction in selling, marketing and advertising expense.

Interest  income for the second quarter of 1997 increased  slightly by $5,000 or
7%  to  $80,000  reflecting  higher  average  cash  balances.  Interest  expense
decreased by $45,000 or 14% to $269,000 due mainly to principal repayments.

The net loss for the period of $632,000 represented an improvement of $1,426,000
or 69% over the corresponding period of the prior year.

Results of Operations for the Six Months Ended June 30, 1997 and 1996

Microsponge  product and  technology  revenues for the six months ended June 30,
1997 increased by $4,540,000 or 129% to $8,047,000 compared to the corresponding
quarter of the prior year.  This  increase was due mainly to the launches of new
products  incorporating the Company's proprietary technology which were licensed
by three key marketing partners  --Retin-A(R)  Micro(TM) by Ortho Dermatological
for which the Company received FDA marketing clearance in February 1997, ANEW(R)
Retinol  Recovery  Complex PM  Treatment  which is marketed by Avon,  Inc.,  and
TxSystems(TM)  AFIRM(TM) retinol formulation which is marketed by Medicis.  Also
included  in  revenues  in the first  half of 1997 was a  milestone  payment  of
$1,500,000, representing half of the $3,000,000

                                       10
<PAGE>

received from Ortho  Dermatological on the FDA marketing clearance of Retin-A(R)
Micro(TM).  The remaining $1,500,000 was prepaid royalties which was recorded as
deferred revenue.

The first half of 1996  included  revenues  of  $7,000,000  relating to sales of
consumer products which are no longer marketed by the Company.

Gross profit on product and technology revenues for the first six months of 1997
of $4,603,000 or 57% compared with $4,213,000 or 40% in the corresponding period
of the prior year.  This was due  primarily to increased  sales of higher margin
proprietary cosmeceutical products and increased manufacturing volume.

Operating  expenses for the first six months of 1997  decreased by $1,933,000 or
25%. This was due primarily to a reduction in selling, marketing and advertising
expense of $2,301,000 or 52% to $2,123,000.  This decrease was mainly due to the
fact the Company  licensed  its consumer  products to Lander  Company in January
1997 and discontinued sales of in-licensed  suncare products,  thus avoiding the
high cost of advertising and distributing consumer products.

Research and development expense decreased by $41,000 or 2% to $1,833,000.  This
was due mainly to a  reallocation  of  resources  as the  Company's  proprietary
technologies  are  being  increasingly  commercialized  and the  fact  that  the
year-ago period included FDA filing fees for Retin-A(R)  Micro(TM) for which the
Company  received  marketing  clearance in February 1997.  These  decreases were
partially  offset by  increased  spending  in the  first  six  months of 1997 on
clinical  studies and patent  protection for products which have been both newly
licensed and internally developed.

General  and  administrative  expense  for the first half of 1997  increased  by
$409,000  or  27%  over  the  year-ago   period  due  mainly  to  a  variety  of
non-recurring outside services.

Interest  income for the first six months of 1997 was  $159,000,  an increase of
$46,000 or 40%, due mainly to higher average cash balances. Interest expense for
the same  period  of  $540,000  decreased  by  $73,000  or 12% due to  principal
repayments.

The net loss  for the  first  six  months  of 1997 of  $213,000  represented  an
improvement  of  $3,865,000  or 95% over the  corresponding  period of the prior
year.

Capital Resources and Liquidity

Total assets as of June 30, 1997 were  $21,039,000  compared with $18,444,000 at
December 31, 1996, and working capital  increased to $4,042,000 from $3,800,000.
In the same  period,  cash and cash  equivalents  increased to  $7,450,000  from
$5,395,000. During the first six months, the Company's operating activities used
$1,022,000  of cash.  This  principally  related to an increase in inventory and
receivables as a result of the

                                       11
<PAGE>

launches  of  new  products  by  corporate   partners.   The  Company   invested
approximately  $1,833,000 in product  research and development and $2,123,000 in
selling and marketing the Company's products and technologies.

The  Company  has  financed  its  operations,  including  product  research  and
development,  from  amounts  raised in debt and equity  financings,  the sale of
Microsponge   delivery  systems,   consumer  products  and  analytical  standard
products;  payments received under licensing agreements;  and interest earned on
short-term investments.

In the first six months of 1997,  upon receipt of marketing  clearance  from the
FDA to market Retin-A Micro  (tretinoin  gel)  microsphere  for the treatment of
acne, APS received $3,000,000 from Ortho McNeil Pharmaceutical of which one half
was a milestone  payment which was recognized as revenue in the first quarter of
1997 and half was prepaid royalties which was recorded as deferred revenue.

In  June  1997,   approximately  300,000  warrants  which  had  been  issued  in
conjunction with a 1994 private  placement were exercised.  The Company received
approximately $1,650,000 from the exercise of these warrants.

The Company's existing cash and cash equivalents,  collections of trade accounts
receivable, together with interest income and other revenue producing activities
including licensing fees and milestone  payments,  are expected to be sufficient
to meet the Company's working capital  requirements for the foreseeable  future,
assuming no changes to existing business plans.

New Accounting Standards

In February 1997, the Financial  Accounting  Standards Board issued Statement of
Financial  Accounting  Standards No. 128, "Earnings per Share" (SFAS 128), which
will be effective for financial statements for periods ending after December 15,
1997,  including  interim periods,  and establishes  standards for computing and
presenting  earnings per share.  Earlier  application is not  permitted.  In its
consolidated  financial  statements  for the year ending  December 31, 1997, the
Company will make the  required  disclosures  of basic and diluted  earnings per
share.  All prior period earnings per share data will be restated by the Company
upon adoption of SFAS 128.

In June 1997,  the  Financial  Accounting  Standards  Board issued  Statement of
Financial  Accounting Standards No. 130 "Reporting  Comprehensive  Income" (SFAS
130) which will be effective  for  financial  statements  for periods  beginning
after December 15, 1997, and establishes  standards for reporting and display of
comprehensive  income  and  its  components  in a full  set of  general  purpose
financial  statements.  Earlier application is permitted.  The Company will make
the required  reporting of comprehensive  income in its  consolidated  financial
statements for the first quarter ending March 31, 1998.

                                       12
<PAGE>

In June 1997,  the  Financial  Accounting  Standards Board  issued  Statement of
Financial Accounting Standards No. 131 "Disclosures about Segments of a Business
Enterprise"  (SFAS  131)  which  will  be  effective  for  financial  statements
beginning  after December 15, 1997, and  establishes  standards for  disclosures
about segments of an  enterprise.  Earlier  application  is  encouraged.  In its
consolidated  financial  statements  for the year December 31, 1998, the Company
will make the required disclosures.

                                       13


<PAGE>

PART II.

       Item 1. Legal Proceedings

                    None

       Item 4. Submission of Matters to a Vote of Security Holders

                    The Company's annual shareholder's  meeting was held on June
                    18, 1997, at which the following proposals were approved:

                    Proposal I:  Election of the following Directors:

                                                      Votes           Votes
                                                       For           Withheld
                                                       ---           --------
                    John J. Meakem, Jr.             16,612,705       125,741
                      Chairman of the Board
                    Carl Ehmann                     16,619,306       119,140
                    Jorge Heller                    16,613,676       124,770
                    Peter Riepenhausen              16,615,306       123,140
                    Toby Rosenblatt                 16,613,946       124,500
                    Gregory Turnbull                16,616,356       122,090
                    Charles Anthony Wainwright      16,594,081       144,365
                    Dennis Winger                   16,620,006       110,040

                    Proposal II: To approve an amendment to the  Company's  1992
                    Stock Option Plan to limit the number of shares with respect
                    to which  options  may be  granted  to no more than  250,000
                    shares to any one participant in any one-year period.

                    Votes For    Votes Against    Abstentions & Broker Non Votes
                    ---------    -------------    ------------------------------
                    16,277,765      278,837                  181,844

                    Proposal III: To approve the Company's  1997 Employee  Stock
                    Purchase Plan covering  400,000  shares  issuable  under the
                    Plan.

                    Votes For    Votes Against    Abstentions & Broker Non Votes
                    ---------    -------------    ------------------------------
                    14,383,855     2,174,142                 180,449

       Item 6. Exhibits and Reports on Form 8-K

                    (a)   Exhibits:    27        Financial Data Schedules

                    (b)   Reports on Form 8-K:  None

                                       14


<PAGE>

                                   SIGNATURES

       Pursuant to the requirements of the Securities  Exchange Act of 1934, the
       registrant  has duly caused this report to be signed on its behalf by the
       undersigned thereunto duly authorized.




                                         ADVANCED POLYMER SYSTEMS, INC.





         Date: August 12, 1997           By: /s/ John J. Meakem, Jr.
              ----------------              ------------------------
                                                John J. Meakem, Jr.
                                                Chairman, President and
                                                Chief Executive Officer



         Date: August 12, 1997           By: /s/ Michael O'Connell
              ----------------              ----------------------
                                                Michael O'Connell
                                                Executive Vice President,
                                                Chief Administrative Officer and
                                                Chief Financial Officer


                                       15
<PAGE>


 

                                  EXHIBIT INDEX

                                    Form 10-Q

                         ADVANCED POLYMER SYSTEMS, INC.

27       -Financial Data Schedules.


<TABLE> <S> <C>


<ARTICLE> 5
<MULTIPLIER> 1
       
<S>                                <C>
<PERIOD-TYPE>                      6-MOS
<FISCAL-YEAR-END>                                    DEC-31-1997
<PERIOD-START>                                       JAN-01-1997
<PERIOD-END>                                         JUN-30-1997
<CASH>                                                   7,449,934
<SECURITIES>                                                     0
<RECEIVABLES>                                            3,259,074
<ALLOWANCES>                                                34,351
<INVENTORY>                                              2,618,969
<CURRENT-ASSETS>                                        13,784,031
<PP&E>                                                  14,018,846
<DEPRECIATION>                                           9,089,130
<TOTAL-ASSETS>                                          21,039,439
<CURRENT-LIABILITIES>                                    9,742,490
<BONDS>                                                  4,330,705
                                            0
                                                      0
<COMMON>                                                   187,456
<OTHER-SE>                                               6,778,788
<TOTAL-LIABILITY-AND-EQUITY>                            21,039,439
<SALES>                                                  6,500,901
<TOTAL-REVENUES>                                         9,546,648
<CGS>                                                    3,443,694
<TOTAL-COSTS>                                            3,443,694
<OTHER-EXPENSES>                                         5,869,171
<LOSS-PROVISION>                                                 0
<INTEREST-EXPENSE>                                         540,254
<INCOME-PRETAX>                                           (212,811)
<INCOME-TAX>                                                     0
<INCOME-CONTINUING>                                       (212,811)
<DISCONTINUED>                                                   0
<EXTRAORDINARY>                                                  0
<CHANGES>                                                        0
<NET-INCOME>                                              (212,811)
<EPS-PRIMARY>                                                (0.01)
<EPS-DILUTED>                                                (0.01)
        

</TABLE>


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