ADVANCED POLYMER SYSTEMS INC /DE/
10-Q, 1999-05-14
PLASTIC MATERIALS, SYNTH RESINS & NONVULCAN ELASTOMERS
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                              FORM 10-Q
                  SECURITIES AND EXCHANGE COMMISSION
                       Washington, D.C.  20549


[X]        Quarterly Report Under Section 13 or 15(d)
             of the Securities Exchange Act of 1934

           For the quarterly period ended March 31, 1999


[ ]        Transition Report Pursuant to Section 13 or 15(d)
                of the Securities Exchange Act of 1934

          For the transition period from          to         
                                         --------    --------

                    Commission file Number 0-16109


                    ADVANCED POLYMER SYSTEMS, INC.
                    ------------------------------
         (Exact name of registrant as specified in its charter)


        Delaware                                       94-2875566
- -------------------------------                ------------------------
(State or other jurisdiction of                           (IRS Employer
incorporation or organization)                      Identification No.)


               123 Saginaw Drive, Redwood City, CA  94063
               ------------------------------------------
                (Address of principal executive offices)

                           (650) 366-2626
          ----------------------------------------------------
          (Registrant's telephone number, including area code)

Indicate by check mark whether the registrant (1) has filed all reports 
required to be filed by Section 13 or 15 (d) of the Securities Exchange 
Act of 1934 during the preceding 12 months (or for such shorter period 
that the registrant was required to file such reports), and (2) has 
been subject to such filing requirements for the past 90 days.
                                                       Yes  X     No   
                                                           ---      ---

At April 30, 1999, the number of outstanding shares of the Company's 
common stock, par value $.01, was 20,088,286.

<PAGE>
                                INDEX


PART I.    FINANCIAL INFORMATION

ITEM 1. Financial Statements (unaudited):

Condensed Consolidated Balance Sheets 
March 31, 1999 and December 31, 1998

Condensed Consolidated Statements of Operations
for the three months ended March 31, 1999 and 1998

Condensed Consolidated Statements of Cash Flows
for the three months ended March 31, 1999 and 1998

Notes to Condensed Consolidated Financial Statements

ITEM 2. Management's Discussion and Analysis of Financial 
        Condition and Results of Operations


PART II.   OTHER INFORMATION

ITEM 1. Legal Proceedings               

ITEM 6. Exhibits and Reports on Form 8-K

    Signatures


<PAGE>
PART I.    FINANCIAL INFORMATION
           ---------------------
ITEM 1.    Financial Statements (unaudited):
           --------------------------------

CONDENSED CONSOLIDATED BALANCE SHEETS (UNAUDITED)
- -------------------------------------------------
<TABLE>
<CAPTION>

                                      March 31, 1999  December 31, 1998
                                      --------------  -----------------
<S>                                    <C>               <C>
ASSETS
Current assets:
  Cash and cash equivalents            $  5,356,566      $  4,088,173
  Trade accounts receivable, net          2,466,906         2,532,527
  Receivables for royalties,
    license and option fees and
    R&D fees                              2,808,557         2,296,852
  Inventory                               3,169,611         2,959,443
  Advances and loans to officers 
    and employees                           420,632           338,947
  Prepaid expenses and other                657,057           596,400
                                         ----------        ----------

   Total current assets                  14,879,329        12,812,342

Property and equipment, net               8,495,715         8,643,856
Deferred loan costs, net                     44,612            90,428
Goodwill and other intangible
  assets, net                             1,304,978         1,351,813
Other long-term assets                      187,892           182,892
                                         ----------        ----------
Total assets                           $ 24,912,526      $ 23,081,331
                                         ==========        ==========

LIABILITIES & SHAREHOLDERS' EQUITY
Current liabilities:
  Accounts payable                     $  1,292,476      $  1,347,737
  Accrued expenses                        1,403,313         1,057,287
  Accrued settlement liability            1,000,000         1,300,000
  Deferred revenue                          750,000           750,000
  Current portion - long-term debt        1,195,757         3,055,460
                                         ----------        ----------
Total current liabilities                 5,641,546         7,510,484

Deferred revenue - long-term              1,036,517         1,035,855
Long-term debt                            3,088,636                --
                                         ----------        ----------
Total liabilities                         9,766,699         8,546,339
                                         ----------        ----------
Shareholders' equity:
  Common stock and common stock
   warrants                              85,184,563        84,903,633
  Accumulated deficit                   (70,038,736)      (70,368,641)
                                         ----------        ----------
Total shareholders' equity               15,145,827        14,534,992
                                         ----------        ----------
Total liabilities and shareholders'
  equity                               $ 24,912,526      $ 23,081,331
                                         ==========        ==========
<FN>
See accompanying notes.
</FN>
</TABLE>
<PAGE>

CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (UNAUDITED)
- ----------------------------------------------------------
<TABLE>
<CAPTION>

                                 Three Months Ended March 31,
                                 ----------------------------
                                      1999          1998 
                                     ------        ------
<S>                                 <C>           <C>        

Product revenues                    $ 2,950,055   $ 3,509,461
Royalties, license and option
  fees and R&D fees                   1,670,787     1,062,437
                                     ----------    ----------

Total revenues                        4,620,842     4,571,898

Cost of sales                         1,548,172     1,749,611

Operating expenses:
 Research & development, net          1,055,521     1,038,752
 Selling & marketing                    727,085       875,830
 General & administration               850,716       726,686
                                     ----------    ----------

Total operating expenses              2,633,322     2,641,268
                                     ----------    ----------

Operating income                        439,348       181,019

Interest income                          33,700        83,457

Interest expense                       (142,716)     (228,780)

Other expense, net                         (427)       (8,876)
                                     ----------    ----------

Net income                          $   329,905   $    26,820
                                     ==========    ==========

Basic earnings per common share     $      0.02   $      0.00
                                     ==========    ==========

Diluted earnings per common share   $      0.02   $      0.00
                                     ==========    ==========

Weighted average common shares
 outstanding-basic                   20,018,245    19,577,247
                                     ==========    ==========

Weighted average common shares
 outstanding-diluted                 20,241,082    20,358,114
                                     ==========    ==========

<FN>
See accompanying notes.
</FN>
</TABLE>
<PAGE>
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (UNAUDITED)
- -----------------------------------------------------------

<TABLE>
<CAPTION>
                                For the three months ended March 31,
                                ------------------------------------
                                            1999             1998
                                         ----------       ----------
<S>                                     <C>              <C>

Cash flows from operating activities:
Net income                              $   329,905      $    26,820
 Adjustments to reconcile net income to 
  net cash provided by (used in)
  operating activities:
   Depreciation and amortization            269,264          269,853
   Amortization of deferred loan costs       45,816           65,816
   Stock issued to directors                 21,000               --
   Stock compensation awards to non-
    employees                                    --           30,000
   Restricted stock awards                   49,930               --
 Changes in operating assets and 
  liabilities:
   Trade accounts receivable                 65,621         (917,391)
   Receivables for royalties, license
     and option fees and R&D fees          (511,705)        (460,617)
   Inventory                               (210,168)        (339,365)
   Prepaid expenses and other              (142,342)        (135,998)
   Other long-term assets                    (5,000)          40,008
   Accounts payable and accrued expenses    290,765         (752,239)
   Accrued settlement liability            (300,000)              --
   Deferred revenues                            662           (7,229)
                                          ---------        ---------
Net cash used in operating activities       (96,252)      (2,180,342)
                                          ---------        ---------
Cash flows from investing activities:
   Purchases of property and equipment      (74,288)      (1,213,942)
                                          ---------        ---------
Net cash used in investing activities       (74,288)      (1,213,942)
                                          ---------        ---------
Cash flows from financing activities:
   Proceeds from the exercise of common
    stock options and warrants              210,000        1,766,393
   Proceeds from long-term debt           4,000,000               --
   Repayment of debt                     (2,771,067)        (620,778)
                                          ---------        ---------
Net cash provided by financing
 activities                               1,438,933        1,145,615
                                          ---------        ---------
Net (decrease) increase in cash and
 cash equivalents                         1,268,393       (2,248,669)
Cash and cash equivalents, beginning 
 of the period                            4,088,173        8,672,021
                                          ---------        ---------
Cash and cash equivalents, end 
 of the period                          $ 5,356,566      $ 6,423,352
                                          =========        =========
Cash paid for interest                  $    77,273      $   164,472
                                          =========        =========
<FN>
See accompanying notes.
</FN>
</TABLE>
<PAGE>

NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
- ----------------------------------------------------
MARCH 31, 1999 AND DECEMBER 31, 1998 (UNAUDITED)
- ------------------------------------------------

(1)  Basis of Presentation
     ---------------------

In the opinion of management, the accompanying unaudited 
condensed consolidated financial statements contain all 
adjustments, consisting of normal recurring adjustments, 
necessary to present fairly the financial position of Advanced 
Polymer Systems, Inc. and subsidiaries ("the Company" or "APS") 
as of March 31, 1999 and the results of their operations and 
cash flows for the three months ended March 31, 1999 and 1998.

These condensed consolidated statements should be read in 
conjunction with the Company's audited consolidated financial 
statements for the year ended December 31, 1998 included in the 
Company's Annual Report on Form 10-K.

The condensed consolidated financial statements include the 
financial statements of the Company and its subsidiaries, 
Premier, Inc. ("Premier") and APS Analytical Standards, Inc.  
All significant intercompany balances and transactions have 
been eliminated in consolidation.

The Company considers all short-term investments in debt 
securities which have original maturities of less than three 
months to be cash equivalents.  Investments which have original 
maturities longer than three months are classified as 
marketable securities in the accompanying balance sheets.

Certain reclassifications have been made to the prior period 
financial statements to conform with the presentation in 1999.

(2)  Common Shares Outstanding and Earnings Per Share Information
     ------------------------------------------------------------

Common stock outstanding as of March 31, 1999 is as follows:


                                            Number of Shares
                                            ----------------
Common stock outstanding as of 
 December 31, 1998                               19,993,311
Warrants exercised after December 31, 1998           70,000
Shares issued to Directors after December
 31, 1998                                             4,802
                                                 ----------
Total shares                                     20,068,113
                                                 ==========

The following table sets forth the computation of the Company's 
basic and diluted earnings per share:

<TABLE>
<CAPTION>

                                   Three Months Ended
                                        March 31,
                                   ------------------
<S>                                <C>           <C>

                                        1999          1998
                                        ----          ----
Net income available to 
 stockholders (numerator)          $   329,905   $    26,820
                                    ==========    ==========

Shares calculation (denominator):
 Weighted average shares
  outstanding - basic               20,018,245    19,577,247
Effect of dilutive securities:
 Stock options and employee
  stock purchase plan                  104,432       501,844
 Warrants                              118,405       279,023
                                    ----------    ----------
 Weighted average shares
  outstanding - diluted             20,241,082    20,358,114
                                    ==========    ==========

Earnings per share - basic         $      0.02   $      0.00
                                    ==========    ==========

Earnings per share - diluted       $      0.02   $      0.00
                                    ==========    ==========
</TABLE>

Options to purchase 2,761,305 and 1,037,838 shares of Common 
Stock with exercise prices ranging from $5.00 to $15.00 and 
$7.38 to $15.00 per share were outstanding during the quarters 
ended March 31, 1999 and 1998, respectively, but were not 
included in the computation of diluted earnings per share since 
the exercise prices of the options were greater than the 
average market price of the common shares.  The options expire 
between July 23, 2001 and June 23, 2008.

(3)  Related Party Transactions
     --------------------------

During the first quarter of 1999, additional advances totaling 
$102,000 were made to an officer of the Company.  As of March 
31, 1999, the outstanding secured loan receivable from the 
officer totaled $355,000.  During May 1999, $120,000 of the 
loan balance was paid by the officer.  The loan bears an 
interest rate of the lower of 13.87% or the highest rate 
permitted under the applicable law.  The loan was approved by 
the Compensation Committee of the Company's Board of Directors. 
Repayment of the loan is due by December 31, 1999.

(4)  Inventory   
     ---------

The major components of inventory are as follows:

<TABLE>
<CAPTION>
                          March 31, 1999      December 31, 1998
                          --------------      -----------------
<S>                       <C>                 <C>
Raw materials and work-
  in-process              $  906,064          $  743,383
Finished goods             2,263,547           2,216,060
                           ---------           ---------
Total inventory           $3,169,611          $2,959,443
                           =========           =========
     </TABLE>

(5)  Debt
     ----

In March 1999, the Company received a $4,000,000 term loan with 
a fixed interest rate of 13.87%.  The loan is secured by the 
assets of the Company's manufacturing facility in Louisiana and 
a portion of the Company's accounts receivable. Principal and 
interest payments are due in equal monthly installments over a 
period of forty-eight months commencing March 1999.  The term 
loan was obtained mainly to refinance scheduled debt repayments 
made in the first quarter of 1999.

(6)  Legal Proceedings
     -----------------

In November 1997, Biosource Technologies, Inc. filed a 
compliant against the Company in the San Mateo Superior Court. 
 Biosource claimed damages from the Company on the grounds that 
the Company had failed to pay certain minimum amounts allegedly 
due under a contract for the supply of melanin.

In December 1998, the Company reached a settlement agreement 
with Biosource for a net amount of $1,300,000, which consists 
of a $1,500,000 settlement of Biosource's claims and a $200,000 
settlement of the Company's cross claims.  Pursuant to the 
agreement, the Company paid Biosource $300,000 in January, 
1999.  The remaining $1,000,000 will be paid in cash by May 31, 
1999.  The settlement agreement also provides for the 
termination of the license and supply agreement between the 
parties.


<PAGE>
ITEM 2. Management's Discussion and Analysis of Financial Condition
        -----------------------------------------------------------
        and Results of Operations (all dollar amounts rounded to the
        ------------------------------------------------------------
        nearest thousand)
        -----------------

Results of Operations for the Three Months Ended March 31, 1999 and
- -------------------------------------------------------------------
1998
- ----

Except for statements of historical fact, the statements herein are 
forward-looking and are subject to a number of risks and 
uncertainties that could cause actual results to differ materially 
from the statements made.  These include, among others, uncertainty 
associated with timely approval, launch and acceptance of new 
products, establishment of new corporate alliances, progress in 
research and development programs, risks of consummation of the sale 
of the Company (as to which there is no assurance) and other risks 
described below or identified from time to time in the Company's 
Securities and Exchange Commission filings.

The Company's revenues are derived principally from product sales, 
license fees, royalties and R&D fees.  The Company is currently 
manufacturing and selling Microsponge(R) and Polytrap (R) delivery 
systems for use by customers in approximately 100 different personal 
care and cosmetic products. Under strategic alliance arrangements 
entered into with certain corporations, APS can receive non-
refundable upfront fees, future milestone payments, commitments for 
future minimum purchases and royalties based on third party product 
sales or a share of partners' revenues, and revenues from the sale 
of Microsponge and Polytrap systems.

Product revenues for the three months ended March 31, 1999 totaled 
$2,950,000 compared to $3,509,000 in the corresponding period of the 
prior year, representing a decrease of $559,000 or 16%.  This 
decrease is primarily due to the launch of a Microsponge-based 
retinol formulation in the first quarter of the prior year and the 
supply of Microsponge systems to Procter & Gamble for a baby wipe 
product which has now been discontinued.

Royalties, license and option fees, and R&D fees for the first 
quarter of 1999 increased by $608,000 or 57% from the first quarter 
of the prior year to a total of $1,671,000.  Approximately 82% of 
the increase is due to the exercise of an option by a cosmeceutical 
customer to purchase the rights to a certain proprietary product.  
Higher royalties from Ortho Pharmaceutical for Retin-A(R) Micro(TM) 
accounted for 31% of the increase.  These increases were partly 
offset by the absence of royalties from Procter & Gamble for the 
baby wipe product.

Gross profit on product revenues of $1,402,000 decreased as a 
percentage of product revenues from 50% to 48% due mainly to the 
launch of a Microsponge-based retinol formulation in the first 
quarter of the prior year.

Research and development expenses for the first quarter of 1999 were 
essentially flat with the corresponding period of the prior year.  

Selling and marketing expenses decreased by $149,000 or 17% from the 
first quarter of the prior year to $727,000.  The decrease is mostly 
due to lower expenses for outside services relating to print 
promotion activities.

General and administrative expenses totaled $851,000, an increase of 
$124,000 or 17% from the first quarter of the prior year.  This 
increase is primarily attributable to incremental compensation 
expense resulting from restricted stock awards, incremental 
compensation for the Company's Board of Directors, higher travel 
expenses and other outside services.

Interest income decreased by $50,000 or 60% from the first quarter 
of the prior year due to lower average cash balances.  Interest 
expense decreased by $86,000 or 38% to $143,000 due to a decrease in 
outstanding debt compared to the first quarter of the prior year.

Capital Resources and Liquidity
- -------------------------------

Total assets as of March 31, 1999 were $24,913,000 compared with 
$23,081,000 at December 31, 1998.  Working capital increased to 
$9,238,000 from $5,302,000 for the same period and cash and cash 
equivalents increased to $5,357,000 from $4,088,000.  During the 
first three months of 1999, the Company's operating activities used 
$96,000 of cash compared to $2,180,000 in the first quarter of the 
prior year.  The Company invested approximately $1,056,000 in 
product research and development and $727,000 in selling and 
marketing the Company's products and technologies.

Trade accounts receivable decreased slightly to $2,467,000 at March 
31, 1999 from $2,533,000 at December 31, 1998.  Days sales 
outstanding increased to 73 days at March 31, 1999 compared to 68 
days at December 31, 1998. The increase in days sales outstanding is 
mainly due to the timing of product shipments, which was heavily 
weighted towards the last month of the quarter.  Receivables from 
royalties, license and option fees and R&D fees increased to 
$2,809,000 at March 31, 1999 compared to $2,297,000 at December 31, 
1998.  This increase is primarily attributable to certain proceeds 
related to the sale of a proprietary product which are not due for 
payment until the second quarter of 1999.

Capital expenditures for the three months ended March 31, 1999 
decreased substantially to $74,000 compared to $1,214,000 in the 
same period of the prior year.  The first quarter of the prior year 
included capital expenditures related to the plant expansion in the 
Company's manufacturing facility in Louisiana and leasehold 
improvements to the Company's new facility in Redwood City, which 
are now substantially complete.

In March 1999, the Company received a $4,000,000 term loan with a 
fixed interest rate of 13.87%.  The loan is secured by the assets of 
the Company's manufacturing facility in Louisiana and a portion of 
the Company's accounts receivable.  Principal and interest payments 
are due in equal monthly installments over a period of forty-eight 
months commencing March 1999.  The term loan was obtained mainly to 
refinance scheduled debt repayments made in the first quarter of 
1999.

In accordance with the terms of the settlement agreement with 
Biosource, the Company will pay Biosource an amount of $1,000,000 in 
May 1999 in lieu of issuing shares of the Company's common stock.

The Company has financed its operations, including technology and 
product research and development, from amounts raised in debt and 
equity financings, the sale of Microsponge and Polytrap delivery 
systems and analytical standard products; payments received under 
licensing agreements; and interest earned on short-term investments.

The Company's existing cash and cash equivalents, collections of 
trade accounts receivable, together with interest income and other 
revenue producing activities including royalties, license and option 
fees and R&D fees, are expected to be sufficient to meet the 
Company's working capital requirements for the foreseeable future, 
assuming no changes to existing business plans.

Year 2000
- ---------

The Company is conducting a comprehensive review of its internal 
computer systems to ensure these systems are adequate to address the 
issues expected to arise in connection with the Year 2000.  These 
issues include the possibility that software which uses only the 
last two digits to refer to the year will no longer function 
properly for years that begin with 20 rather than 19.  In addition, 
the Company is reviewing the status of its customers and suppliers 
with regard to this issue and assessing the potential impact of non-
compliance by such parties on the Company's operations.

The Company has developed a phased program to address Year 2000 
issues.  The first phase consists of identifying necessary changes 
to application software used by the Company.  The Company utilizes 
an integrated ERP system for the majority of its manufacturing and 
financial systems and has received the Year 2000 compliant version 
of the software from the vendor.  Implementation of the upgraded 
software was completed on September 30, 1998.

The second phase consists of determining whether Company systems not 
addressed in Phase One (including non-IT systems) are Year 2000 
compliant.  Identification of systems that are not Year 2000 
compliant has been completed.  The Company is now in the process of 
upgrading or replacing these systems.  The Company expects to 
upgrade or replace these non-compliant systems by the third quarter 
of 1999.

The third phase consists of determining the extent to which the 
Company may be impacted by third parties' systems, which may not be 
Year 2000-compliant.  The Year 2000 computer issue creates risk for 
the Company from third parties with whom the Company deals on 
financial transactions worldwide.  While the Company expects to 
complete efforts in the second quarter of 1999, there can be no 
assurance that the systems of other companies with which the Company 
deals or on which the Company's systems rely will be converted on a 
timely basis, or that any such failure to convert by another company 
could not have an adverse effect on the Company.

Based on current estimates, management expects the total cost to 
remediate non-compliant systems will be less than $650,000 
(approximately $598,000 of which has been incurred since the project 
was started in early 1998).  Most of the costs incurred were for 
purchases of new systems and related equipment.  The estimate may 
change materially as the Company continues to review and audit the 
result of its work.  The Company expects to fund all costs to 
upgrade or replace systems that are not Year 2000-compliant through 
operating cash flows.

The Company has not yet determined its most likely worst case Year 
2000 scenario.  Potential Year 2000 scenarios are going to be 
considered in the Company's contingency plans.

The Company is currently in the process of developing formal 
contingency plans for addressing any problems which may result if 
the work performed in phase two and three do not successfully 
resolve all issues by the Year 2000.  The Company expects to 
complete its contingency plans in the third quarter of 1999.

Failure to complete any necessary remediation by the Year 2000 may 
have a material adverse impact on the operations of the Company.  
Failure of third parties, such as customers and suppliers, to 
remediate Year 2000 problems in their IT and non-IT systems would 
also have a material adverse impact on the operations of the 
Company.

New Accounting Standards
- ------------------------

In June 1998, the FASB issued SFAS No. 133 "Accounting for 
Derivative Instruments and Hedging Activities" (SFAS 133) which will 
be effective for all fiscal quarters of fiscal years beginning after 
June 15, 1999.  SFAS 133 establishes accounting and reporting 
standards for derivative instruments and for hedging activities.  It 
requires that an entity recognize all derivatives as either assets 
or liabilities in the statement of financial position and measure 
those instruments at fair value.  SFAS 133 generally provides for 
matching the timing of gain or loss recognition on the hedging 
instrument with the recognition of (a) the changes in the fair value 
of the hedged asset or liability that are attributed to the hedged 
risk or (b) the earnings effect of hedged forecasted transactions.  
Earlier application of all provisions of this statement is 
encouraged but it is permitted only as of the beginning of any 
fiscal quarter that begins after issuance of this statement.  The 
Company anticipates that adoption of this statement will not have a 
material effect on the consolidated financial statements.

<PAGE>
PART II. OTHER INFORMATION
         -----------------

ITEM 1.  Legal Proceedings
         -----------------

In November, 1997 Biosource Technologies, Inc. ("Biosource") filed a 
complaint against the Company in the San Mateo Superior Court.  
Biosource claimed damages from the Company on the grounds that the 
Company has failed to pay certain minimum amounts allegedly due 
under a contract for the supply of melanin.

In December 1998, the Company reached a settlement agreement with 
Biosource for a net amount of $1,300,000, which consists of a 
$1,500,000 settlement of Biosource's claims and a $200,000 
settlement of the Company's cross claims.  Pursuant to the 
agreement, the Company paid Biosource $300,000 in January, 1999.  
The remaining $1,000,000 will be paid by the Company in cash by May 
31, 1999.  The settlement agreement also provided for the 
termination of the license and supply agreement between the parties.

ITEM 6.  Exhibits and Reports on Form 8-K
         --------------------------------

(a)  Exhibits:  27  Financial Data Schedule as of and for the three 
months ended March 31, 1999.

<PAGE>
                              SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, 
the registrant has duly caused this report to be signed on its 
behalf by the undersigned thereunto duly authorized.


                                     ADVANCED POLYMER SYSTEMS, INC.



Date: May 13, 1999              By:  /S/ John J. Meakem, Jr.
     --------------                  ----------------------------
                                     John J. Meakem, Jr.
                                     Chairman, President and
                                     Chief Executive Officer



Date: May 13, 1999              By:  /S/ Michael O'Connell
     --------------                  ----------------------------
                                     Michael O'Connell
                                     Executive Vice President,
                                     Chief Administrative Officer
                                     and Chief Financial Officer;
                                     President of Pharmaceutical
                                     Sciences


<PAGE>
                             EXHIBIT INDEX

                               Form 10-Q


EXHIBIT         DESCRIPTION

  27            Financial Data Schedule        


<TABLE> <S> <C>

<ARTICLE>5
<LEGEND>THE SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION 
EXTRACTED FROM THE UNAUDITED CONDENSED CONSOLIDATED BALANCE SHEET AS 
OF MARCH 31, 1999, AND CONDENSED CONSOLIDATED STATEMENT OF 
OPERATIONS FOR THE THREE MONTHS ENDED MARCH 31, 1999, AND IS 
QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL STATEMENTS.
<MULTIPLIER>                                 1
<PERIOD-TYPE>                            3-MOS
<FISCAL-YEAR-END>                  DEC-31-1999
<PERIOD-END>                       MAR-31-1999
<CASH>                               5,356,566
<SECURITIES>                                 0
<RECEIVABLES>                        5,275,463
<ALLOWANCES>                            15,362
<INVENTORY>                          3,169,611
<CURRENT-ASSETS>                    14,879,329
<PP&E>                              17,997,088
<DEPRECIATION>                       9,501,373
<TOTAL-ASSETS>                      24,912,526
<CURRENT-LIABILITIES>                5,641,546
<BONDS>                              3,088,636
                        0
                                  0
<COMMON>                               200,681
<OTHER-SE>                          14,945,146
<TOTAL-LIABILITY-AND-EQUITY>        24,912,526
<SALES>                              2,950,055
<TOTAL-REVENUES>                     4,620,842
<CGS>                                1,548,172
<TOTAL-COSTS>                        1,548,172
<OTHER-EXPENSES>                     2,633,322
<LOSS-PROVISION>                        12,700
<INTEREST-EXPENSE>                     142,716
<INCOME-PRETAX>                        329,905
<INCOME-TAX>                                 0
<INCOME-CONTINUING>                    329,905
<DISCONTINUED>                               0
<EXTRAORDINARY>                              0
<CHANGES>                                    0
<NET-INCOME>                           329,905
<EPS-PRIMARY>                             0.02
<EPS-DILUTED>                             0.02

</TABLE>


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