ADVANCED POLYMER SYSTEMS INC /DE/
DEFA14A, 1999-04-27
PLASTIC MATERIALS, SYNTH RESINS & NONVULCAN ELASTOMERS
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                         SCHEDULE 14A

             INFORMATION REQUIRED IN PROXY STATEMENT
                    SCHEDULE 14A INFORMATION

        PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE
                 SECURITIES EXCHANGE ACT OF 1934

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Check the appropriate box:

/ / Preliminary Proxy Statement

/ / Definitive Proxy Statement
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/X/ Soliciting Material Pursuant to Rule 14a-11(c) or Rule
    14a-12

/ / Confidential, for Use of the Commission Only (as 
    permitted by Rule 14a-6(e)(2))


                 Advanced Polymer Systems, Inc.
             ---------------------------------------
          (Name of Registrant as Specified In Its Charter)

   (Name of Person(s) Filing Proxy Statement, if other than
                        the Registrant)

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           [Advanced Polymer Systems, Inc. logo]

                   123 Saginaw Drive
                 Redwood City, CA 94063

                      NEWS RELEASE
                      ------------

Contacts:
LAUREN FELICE                               GORDON SANGSTER
Investor Relations                               Controller
Ruder-Finn                                   (650) 366-2626
(212) 593-6370

    ADVANCED POLYMER SYSTEMS REAFFIRMS ACTIVE PURSUIT OF 
                STRATEGIC ALTERNATIVES
      Will Oppose Board Nominations by 2.0% Stockholder

REDWOOD CITY, CA -- April 27, 1999 -- Advanced Polymer 
Systems, Inc. (Nasdaq: APOS) announced today that its Board 
of Directors has decided to oppose the Board nominees 
proposed for election at the Company's Annual Meeting of 
Stockholders by Providence Investors LLC.  As previously 
announced by the Company, Providence has advised the Company 
that it controls approximately 2% of the Company's shares 
and has nominated a slate of eight directors to replace the 
entire Board.

"Not only are our current directors intimately familiar with 
our Company but also with the industry in which we operate," 
said John J. Meakem, chairman, president and chief executive 
officer of Advanced Polymer Systems.  "The Board is fully 
committed to maximizing value for all of our stockholders.  
With unanimous Board approval, the Company has commenced the 
process of reviewing all strategic alternatives, including 
the possible sale of the Company, with its investment 
banker, Warburg Dillon Read LLC, which has nationally 
recognized expertise in the drug delivery and pharmaceutical 
fields."

"The Board is convinced that the election of new directors 
would run directly counter to the best interests of our 
stockholders.  The current Board has the confidence of the 
key personnel of the Company, including its Research & 
Development staff, and intimate knowledge of the drug 
delivery industry.  A change in the Board at this time 
would be highly disruptive to the process we are actively 
pursuing and would raise significant concerns with current 
and future business partners.  It would also be very 
unsettling to our key management and other personnel, who 
represent a unique and very important asset to the Company."

Advanced Polymer Systems will be filing shortly with the 
Securities and Exchange Commission its preliminary proxy 
materials for the 1999 Annual Meeting.  The Board has set 
June 16, 1999 as the date of the Annual Meeting and the 
record date, as previously notified by the Company's proxy 
distribution agent to the brokerage community, is April 22, 
1999.

Advanced Polymer Systems is a leader in polymer-based 
delivery systems and related technologies used primarily in 
ethical and over-the-counter (OTC) pharmaceuticals and 
personal care products.  The Company's Microsponge(R) and 
Polytrap(R) systems, which deliver active ingredients to the 
skin, now play an integral role in almost 100 personal care 
products sold worldwide.  New products and technologies 
under development include site-specific systems for 
delivering oral medications to the lower gastrointestinal 
tract, and bioerodible microspheres and polymers for oral or 
implantable drug delivery.

Forward-looking Statements
- --------------------------

This news release, other than the historical financial 
information, consists of forward-looking statements that 
involve risks and uncertainties, including the risks of 
consummation of the sale of the Company (as to which there 
is no assurance) and the outcome of the contested election 
of directors at the Company's 1999 Annual Meeting of 
Stockholders.  Other risks and uncertainties associated with 
the Company's business and prospects are identified in the 
Company's filings with the Securities and Exchange 
Commission.  The Company does not undertake to revise these 
forward-looking statements to reflect events or 
circumstances occurring in the future.

CERTAIN INFORMATION CONCERNING PARTICIPANTS

The following individuals, all of whom are directors or 
executives of Advanced Polymer Systems, Inc., may be deemed 
participants in the solicitation of proxies on behalf of the 
Company's Board of Directors: John J. Meakem, Jr. (Chairman 
of the Board, Chief Executive Officer and President of the 
Company); Carl Ehmann, M.D., F.A.C.P. (Group Director, 
Global Research and Development, Reckitt & Colman, plc.); 
Jorge Heller, Ph.D. (full time Consultant to the Company as 
its Chief Scientist); Peter Riepenhausen (Business 
Consultant); Toby Rosenblatt (President, The Glen Ellen 
Company; Vice President; Founders Investments, Ltd.); 
Gregory H. Turnbull (Business Consultant, Venture Capitalist 
and former Investment Banker); Charles Anthony Wainwright 
(Chairman, McKinney & Silver); Dennis Winger (Senior Vice 
President and Chief Financial Officer, Perkin-Elmer); 
Michael O'Connell (Executive Vice President, Chief Financial 
and Administrative Officer); and Gordon Sangster (Vice 
President, Controller of the Company).

Mr. Meakem beneficially owns 905,967 shares of Company 
Common Stock (including 654,247 shares subject to stock 
options exercisable within 60 days of April 22, 1999).  Dr. 
Ehmann beneficially owns 67,686 shares of Company Common 
Stock (including 65,000 shares subject to stock options 
exercisable within 60 days of April 22, 1999).  Dr. Heller 
beneficially owns 100,686 shares of Company Common Stock 
(including 90,000 shares subject to stock options 
exercisable within 60 days of April 22, 1999).  Mr. 
Riepenhausen beneficially owns 93,686 shares of Company 
Common Stock, directly and in joint tenancy with his wife 
(including 85,000 shares subject to stock options 
exercisable within 60 days of April 22, 1999).  Mr. 
Rosenblatt beneficially owns 266,212 shares of Company 
Common Stock (including 75,000 shares subject to stock 
options exercisable within 60 days of April 22, 1999).  Mr. 
Turnbull beneficially owns 75,686 shares of Company Common 
Stock (including 75,000 shares subject to stock options 
exercisable within 60 days of April 22, 1999).  Mr. 
Wainwright beneficially owns 24,186 shares of Company Common 
Stock (including 22,500 shares subject to stock options 
exercisable within 60 days of April 22, 1999).  Mr. Winger 
beneficially owns 75,686 shares of Company Common Stock 
(including 75,000 shares subject to stock options 
exercisable within 60 days of April 22, 1999).  Mr. 
O'Connell beneficially owns 371,526 shares of Company Common 
Stock (including 346,249 shares subject to stock options 
exercisable within 60 days of April 22, 1999).  Mr. Sangster 
beneficially owns 88,661 shares of Company Common Stock 
(including 88,334 shares subject to stock options 
exercisable within 60 days of April 22, 1999).

Under the Company's 1992 Stock Option Plan, each nonemployee 
director receives an automatic grant of an option to acquire 
10,000 shares of Company Common Stock and a one-time 
automatic grant to acquire 25,000 shares when first elected 
as a director.  In addition, nonemployee directors receive 
$12,000 per year, payable in quarterly installments, one-
half in cash and one-half in unregistered Company Common 
Stock valued at the closing price of the Company's Common 
Stock on the last trading day of each quarter.  Nonemployee 
directors also receive $1,000 for each meeting of the Board 
of Directors attended and $500 for each committee meeting 
attended on a date other than the date of regularly 
scheduled Board Meetings.

Mr. Meakem is a party to an employment agreement (as 
amended) with the Company which automatically renews each 
year unless terminated in accordance with the agreement by 
either the Company or Mr. Meakem.  The employment agreement 
provides for, among other things, certain payments if (i) 
the Company terminates Mr. Meakem's employment within a 
specified period of a change of control of the Company or 
(ii) Mr. Meakem elects to terminate his employment following 
a change in control of the Company if his position with the 
Company is reduced in terms of responsibility or indicia of 
status.

Dr. Ehmann, Mr. Riepenhausen and Mr. Wainwright provide 
consulting services to the Company, for which they received 
$3,000, $7,500 and $4,500, respectively, in 1998.  Dr. 
Heller acts as a full time Consultant to the Company for 
which he received $160,000 in 1998.



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