ADVANCED POLYMER SYSTEMS INC /DE/
DEFA14A, 1999-05-03
PLASTIC MATERIALS, SYNTH RESINS & NONVULCAN ELASTOMERS
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                         SCHEDULE 14A

             INFORMATION REQUIRED IN PROXY STATEMENT
                    SCHEDULE 14A INFORMATION

        PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE
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    14a-12

/ / Confidential, for Use of the Commission Only (as 
    permitted by Rule 14a-6(e)(2))


                 Advanced Polymer Systems, Inc.
             ---------------------------------------
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   (Name of Person(s) Filing Proxy Statement, if other than
                        the Registrant)

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           [Advanced Polymer Systems, Inc. logo]

                   123 Saginaw Drive
                 Redwood City, CA 94063

                      NEWS RELEASE
                      ------------

Contacts:
LAUREN FELICE                               GORDON SANGSTER
Investor Relations                               Controller
Ruder-Finn                                   (650) 366-2626
(212) 593-6370

        ADVANCED POLYMER SYSTEMS AND ALBERTO-CULVER
                SIGN MARKETING AGREEMENT 

       Microsponge(R)-based Vitamin K and Retinol Skin 
       Treatments to be Marketed through Another Major 
               Partner in Mass Retail Channel

REDWOOD CITY, CA -- May 3, 1999 -- Advanced Polymer Systems, 
Inc. (Nasdaq: APOS) and The Alberto-Culver Company (NYSE: 
ACVA; ACV) today announced that they have entered into an 
agreement to commercialize two Microsponge(R)-based 
products under the St. Ives Swiss Formula(R) brand name 
through the mass retail channel.  The products, which have 
been specially formulated for Alberto-Culver, include the 
first Microsponge-based Vitamin K formulation for under-eye 
treatment and a Microsponge-based retinol anti-wrinkle 
cream.  They are expected to be launched during the second 
half of this year through drugstores, supermarkets and mass 
merchandisers in the United States and Canada.

"Under terms of the agreement, we will supply Alberto-
Culver with the finished products for marketing by their 
expert national sales organizations," said John J. Meakem, 
Jr., chairman, president and chief executive officer of 
Advanced Polymer.  "In conjunction with our commitment to 
developing a significant market presence for a Microsponge-
based Vitamin K formulation, we are very pleased to 
introduce the first Microsponge-based Vitamin K formulation 
with Alberto-Culver and its large distribution network.  
This agreement represents another significant step forward 
in Advanced Polymer's plan to establish a strong 
competitive position in the growing anti-aging skin care 
market."

"We are very excited about these new Microsponge-based 
additions to Alberto-Culver's St. Ives Swiss Formula 
product line," said a spokesperson of Alberto-Culver.  "The 
Vitamin K under-eye treatment will enable our customers to 
reduce the appearance of dark circles under the eyes, 
further increasing the clarity of their skin.  The retinol 
anti-wrinkle cream will enable our customers to reduce the 
appearance of fine lines, large pores and age spots, 
thereby giving their skin a young-looking, radiant glow.  
We have scheduled an aggressive advertising campaign, with 
the objective of making these two innovative new skin care 
products leaders in their field."

The Alberto-Culver Company is a $1.9 billion manufacturer 
and marketer of personal care and household brands.  Its 
Alberto VO5 brand of hair care products and St. Ives Swiss 
Formula hair and skin care products are marketed both in 
the U.S. and internationally.  The Company also owns Sally 
Beauty Supply, the world's largest seller of professional 
beauty supplies.

Advanced Polymer Systems is a leader in polymer-based 
delivery systems and related technologies used primarily in 
ethical and over-the-counter (OTC) pharmaceuticals and 
personal care products.  The company's Microsponge(R) and 
Polytrap(R) systems, which deliver active ingredients to 
the skin, now play an integral role in almost 100 personal 
care products sold worldwide.  New products and 
technologies under development include site-specific 
systems for delivering oral medications to the lower 
gastrointestinal tract, and bioerodible microspheres and 
polymers for oral or implantable drug delivery.

Except for historical information, this news release 
contains certain forward-looking statements that involve 
risks and uncertainties, including among others, 
uncertainty associated with timely approval, launch and 
acceptance of new products, establishment of new corporate 
alliances, progress in research and development programs 
and risks of consummation of the sale of the Company (as to 
which there is no assurance) and the outcome of the 
contested election of directors at the Company's 1999 
Annual Meeting of Stockholders.  Other risks and 
uncertainties associated with the Company's business and 
prospects are identified in the Company's filings with the 
Securities and Exchange Commission.  The Company does not 
undertake to revise these forward-looking statements to 
reflect events or circumstances occurring in the future.

        CERTAIN INFORMATION CONCERNING PARTICIPANTS

The following individuals, all of whom are directors or 
executives of Advanced Polymer Systems, Inc., may be deemed 
participants in the solicitation of proxies on behalf of 
the Company's Board of Directors: John J. Meakem, Jr. 
(Chairman of the Board, Chief Executive Officer and 
President of the Company); Carl Ehmann, M.D., F.A.C.P. 
(Group Director, Global Research and Development, Reckitt & 
Colman, plc.); Jorge Heller, Ph.D. (full time Consultant to 
the Company as its Chief Scientist); Peter Riepenhausen 
(Business Consultant); Toby Rosenblatt (President, The Glen 
Ellen Company; Vice President; Founders Investments, Ltd.); 
Gregory H. Turnbull (Business Consultant, Venture 
Capitalist and former Investment Banker); Charles Anthony 
Wainwright (Chairman, McKinney & Silver); Dennis Winger 
(Senior Vice President and Chief Financial Officer, Perkin-
Elmer); Michael O'Connell (Executive Vice President, Chief 
Financial and Administrative Officer); and Gordon Sangster 
(Vice President, Controller of the Company).

Mr. Meakem beneficially owns 905,967 shares of Company 
Common Stock (including 654,247 shares subject to stock 
options exercisable within 60 days of April 22, 1999).  Dr. 
Ehmann beneficially owns 67,686 shares of Company Common 
Stock (including 65,000 shares subject to stock options 
exercisable within 60 days of April 22, 1999).  Dr. Heller 
beneficially owns 100,686 shares of Company Common Stock 
(including 90,000 shares subject to stock options 
exercisable within 60 days of April 22, 1999).  Mr. 
Riepenhausen beneficially owns 93,686 shares of Company 
Common Stock, directly and in joint tenancy with his wife 
(including 85,000 shares subject to stock options 
exercisable within 60 days of April 22, 1999).  Mr. 
Rosenblatt beneficially owns 266,212 shares of Company 
Common Stock (including 75,000 shares subject to stock 
options exercisable within 60 days of April 22, 1999).  Mr. 
Turnbull beneficially owns 75,686 shares of Company Common 
Stock (including 75,000 shares subject to stock options 
exercisable within 60 days of April 22, 1999).  Mr. 
Wainwright beneficially owns 24,186 shares of Company 
Common Stock (including 22,500 shares subject to stock 
options exercisable within 60 days of April 22, 1999).  Mr. 
Winger beneficially owns 75,686 shares of Company Common 
Stock (including 75,000 shares subject to stock options 
exercisable within 60 days of April 22, 1999).  Mr. 
O'Connell beneficially owns 371,526 shares of Company 
Common Stock (including 346,249 shares subject to stock 
options exercisable within 60 days of April 22, 1999).  Mr. 
Sangster beneficially owns 88,661 shares of Company Common 
Stock (including 88,334 shares subject to stock options 
exercisable within 60 days of April 22, 1999).

Under the Company's 1992 Stock Option Plan, each 
nonemployee director receives an automatic grant of an 
option to acquire 10,000 shares of Company Common Stock and 
a one-time automatic grant to acquire 25,000 shares when 
first elected as a director.  In addition, nonemployee 
directors receive $12,000 per year, payable in quarterly 
installments, one-half in cash and one-half in unregistered 
Company Common Stock valued at the closing price of the 
Company's Common Stock on the last trading day of each 
quarter.  Nonemployee directors also receive $1,000 for 
each meeting of the Board of Directors attended and $500 
for each committee meeting attended on a date other than 
the date of regularly schedule Board Meetings.

Mr. Meakem is a party to an employment agreement (as 
amended) with the Company which automatically renews each 
year unless terminated in accordance with the agreement by 
either the Company or Mr. Meakem.  The employment agreement 
provides for, among other things, certain payments if (i) 
the Company terminates Mr. Meakem's employment within a 
specified period of a change of control of the Company or 
(ii) Mr. Meakem elects to terminate his employment 
following a change in control of the Company if his 
position with the Company is reduced in terms of 
responsibility or indicia of status.

Dr. Ehmann, Mr. Riepenhausen and Mr. Wainwright provide 
consulting services to the Company, for which they received 
$3,000, $7,500 and $4,500, respectively, in 1998.  Dr. 
Heller acts as a full time Consultant to the Company for 
which he received $160,000 in 1998.



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