SOMATOGEN INC
S-8, 1997-11-07
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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 As filed with the Securities and Exchange Commission on November 7, 1997
 Registration No.33-

                         SECURITIES AND EXCHANGE COMMISSION
                              Washington, D.C. 20549


                                     FORM S-8
                                REGISTRATION STATEMENT
                                        UNDER
                             THE SECURITIES ACT OF 1933


                                  Somatogen, Inc.
                  (Exact name of registrant as specified in its charter)

       Delaware                                          84-0991858
(State of Incorporation)                    (I.R.S. Employer Identification No.)

                         2545 Central Avenue, Suite FD1
                          Boulder, Colorado 80301-2857
                                   (303) 440-9988
           (Address and telephone number of principal executive offices)

                  Amended and Restated Consultants Stock Option Plan
              Amended and Restated Nonemployee Director Stock Option Plan
                               (Full title of the plans)

                                  Timothy D. Hoogheem
                  Senior Vice President of Finance and Administration,
               Chief Financial Officer, Treasurer and Assistant Secretary
                                     SOMATOGEN, INC.
                             2545 Central Avenue, Suite FD1
                              Boulder, Colorado 80301-2857
                                     (303) 440-9988
              (Name, address, including zip code, and telephone number,
                        including area code, of agent for service)


                                      Copies to:

                                James C.T. Linfield, Esq.
                                    Cooley Godward LLP
                                2595 Canyon Blvd., Suite 250
                                   Boulder, Colorado 80302
                                       (303) 546-4000


                 Approximate date of commencement of proposed sale to
                       the public:  As soon as practicable after
                     this Registration Statement becomes effective.

                                                                  Page 1 of 7
                                                     Exhibit Index at Page: 7


<PAGE> 2

<TABLE>
<CAPTION>

                               CALCULATION OF REGISTRATION FEE

<S>                        <C>                <C>                      <C>                       <C>

 ========================  =================  ======================== ========================= =======================
                                                 Proposed Maximum          Proposed Maximum
  Title of Securities to     Amount to be       Offering Price Per        Aggregate Offering           Amount of
      be Registered         Registered (1)           Share (2)                 Price (2)             Registration Fee
 ========================= =================  ======================== ========================= =======================
 Stock Options and
 Common Stock (par value         300,000               $6.5625                 $1,968,750                 $596.53
 $.001)
 ========================= ================= ========================= ========================= =======================

</TABLE>

(1)      Comprised of 200,000 and 100,000 shares of Common Stock to be 
         registered under the Amended and Restated Nonemployee Director
         Stock Option Plan and the Amended and Restated Consultants Stock 
         Option Plan, respectively.

(2)      Estimated  solely  for the  purpose  of  calculating  the amount of the
         registration  fee. The offering price per share and aggregate  offering
         price  are based  upon the  closing  price as  reported  on the  Nasdaq
         National   Market,   pursuant  to  Rule  457(h)  of  the  Act,  of  the
         Registrant's  Common Stock on November 3, 1997,  for shares  subject to
         options  to be  granted  under the  Amended  and  Restated  Nonemployee
         Director  Stock  Option Plan and the Amended and  Restated  Consultants
         Stock Option Plan.

                     INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

         The  following   documents   filed  by  Somatogen,   Inc.,  a  Delaware
corporation (the "Company" or the "Registrant") with the Securities and Exchange
Commission  (the   "Commission")   are   incorporated  by  reference  into  this
Registration Statement:

         (a) The Company's  Annual Report on Form 10-K for the fiscal year ended
June 30, 1997;

         (b) The  Registrant's  Quarterly  Report on Form  10-Q for the  quarter
ended September 30, 1997;

         (c) A description of the Company's Common Stock,  which is contained in
the Form 8-A  Registration  Statement  filed by the Company with the  Commission
which was  declared  effective  on August 1, 1991,  as amended  through the date
hereof; and

<PAGE> 3

         (d) All reports and other documents  subsequently  filed by the Company
pursuant to Sections 13(a),  13(c), 14 and 15(d) of the Securities  Exchange Act
of 1934, as amended (the "Exchange Act") prior to the filing of a post-effective
amendment  which  indicates that all securities  offered have been sold or which
deregisters  all  securities  then  remaining  unsold,  shall  be  deemed  to be
incorporated by reference herein and to be a part of this registration statement
from the date of the filing of such reports and documents.


                          DESCRIPTION OF SECURITIES

         Not applicable.


                   INTERESTS OF NAMED EXPERTS AND COUNSEL

         The validity of the issuance of the Common  Stock  offered  pursuant to
the Amended and Restated  Nonemployee Director Stock Option Plan and the Amended
and Restated  consultants  Stock Option Plan will be passed upon for the Company
by Cooley Godward LLP. As of the date hereof,  certain members of Cooley Godward
LLP beneficially owned 19,794 shares of Common Stock.


                 INDEMNIFICATION OF DIRECTORS AND OFFICERS

         Under Section 145 of the Delaware General  Corporation Law, the Company
has broad powers to indemnify  its directors  and officers  against  liabilities
they may incur in such  capacities,  including  liabilities  under the Act.  The
Company's  Bylaws  require the Company to indemnify  its directors and executive
officers, and permit the Company to indemnify its employees and other agents, to
the extent  permitted by Delaware law. Under the company's  Bylaws,  indemnified
parties are entitled to  indemnification  for negligence,  gross  negligence and
otherwise  to the fullest  extent  permitted by law. The Bylaws also require the
Company to advance  litigation  expenses in the case of  stockholder  derivative
actions or other actions,  against an undertaking  by the  indemnified  party to
repay such advances if it is ultimately determined that the indemnified party is
not entitled to indemnification.

         The Company  has entered  into  indemnity  agreements  with each of its
directors and executive  officers.  Such indemnity agreements contain provisions
which are in some respects broader than the specific indemnification  provisions
contained in Delaware law.


                                  EXHIBITS

Exhibit
Number

    3.4*    Bylaws.
    4.1*    Certificate  of  Incorporation, as amended.   
    4.5*    Specimen  stock certificate. 
    5.1     Opinion of Cooley Godward LLP.
   23.1     Consent of Price Waterhouse LLP, Independent Accountants.
   23.3     Consent of Cooley Godward LLP. Reference is made to Exhibit 5.1.
   24.1     Power of Attorney.  Reference is made to the signature page.
   10.78    Registrant's Amended and Restated Nonemployee Director Stock Option
            Plan.
   10.79    Registrant's Amended and Restated Consultants Stock Option Plan.

- -----------------------

*        Filed  as an  exhibit  to the  Form  S-1  Registration  Statement  (No.
         33-41229),  as amended through the date hereof, and incorporated herein
         by reference.



<PAGE> 4



                                  UNDERTAKINGS

I.       The undersigned registrant hereby undertakes:

         A. To file,  during any period in which offers or sales are being made,
a post-effective amendment to this registration statement:

             1. To include any prospectus required by section 10(a)(3) of the
Securities Act;

             2. To reflect in the  prospectus  any facts or events arising after
the  effective  date  of  the   registration   statement  (or  the  most  recent
post-effective  amendment  thereof)  which,  individually  or in the  aggregate,
represent a fundamental  change in the information set forth in the registration
statement.  Notwithstanding the foregoing, any increase or decrease in volume of
securities  offered (if the total dollar value of  securities  offered would not
exceed that which was  registered) and any deviation from the low or high end of
the estimated  maximum offering range may be reflected in the form of prospectus
filed with the  Commission  pursuant  to Rule  424(b)  (ss.  230.424(b)  of this
chapter) if, in the aggregate, the changes in volume and price represent no more
than a 20%  change  in the  maximum  aggregate  offering  price set forth in the
"Calculation of Registration Fee" table in the effective registration statement.

             3. To include any material  information with respect to the plan of
distribution  not  previously  disclosed  in the  registration  statement or any
material change to such information in the registration statement.

         B.  That,  for the  purpose  of  determining  any  liability  under the
Securities Act, each such  post-effective  amendment shall be deemed to be a new
registration  statement  relating  to the  securities  offered  herein,  and the
offering of such  securities at that time shall be deemed to be the initial bona
fide offering thereof.

         C. To remove from  registration by means of a post-effective  amendment
any of the securities being registered which remain unsold at the termination of
the offering.

II.      The  undersigned   registrant  hereby  undertakes  that,  for  purposes
of  determining  any  liability  under the  Securities  Act,  each filing of the
registrant's  annual  report  pursuant to Section  13(a) or Section 15(d) of the
Exchange Act (and, where  applicable,  each filing of an employee benefit plan's
annual  report   pursuant  to  section  15(d)  of  the  Exchange  Act)  that  is
incorporated by reference in the Registration  Statement shall be deemed to be a
new registration  statement  relating to the securities  offered herein, and the
offering of such  securities at that time shall be deemed to be the initial bona
fide offering thereof.

III.     Insofar as indemnification for liabilities arising under the Securities
Act may be  permitted to  directors,  officers  and  controlling  persons of the
registrant pursuant to the foregoing  provisions,  or otherwise,  the registrant
has been advised that in the opinion of the Securities  and Exchange  Commission
such indemnification is against public policy as expressed in the Securities Act
and is, therefore,  unenforceable. In the event that a claim for indemnification
against such  liabilities  (other than the payment by the registrant of expenses
incurred or paid by a director,  officer or controlling person of the registrant
in the successful defense of any action, suit or proceeding) is asserted by such
director,  officer or controlling person in connection with the securities being
registered, the registrant will, unless in the opinion of its counsel the matter
has been  settled by  controlling  precedent,  submit to a court of  appropriate
jurisdiction the question whether such  indemnification  by it is against public
policy as  expressed  in the  Securities  Act and will be  governed by the final
adjudication of such issue.


<PAGE> 5



                                   SIGNATURES

         Pursuant to the requirements of the Securities Act of 1933, as amended,
the Registrant certifies that it has reasonable grounds to believe that it meets
all of the  requirements  for  filing  on  Form  S-8 and has  duly  caused  this
Registration Statement to be signed on its behalf by the undersigned,  thereunto
duly  authorized,  in Boulder,  State of  Colorado,  on the 7th day of November,
1997.

                                         SOMATOGEN, INC.

                                         By: Timothy D. Hoogheem
                                             Senior Vice President of Finance
                                             and Administration, Chief Financial
                                             Officer, Treasurer and Assistant
                                             Secretary


                                POWER OF ATTORNEY

         KNOW ALL PERSONS BY THESE  PRESENTS,  that each person whose  signature
appears  below  constitutes  and appoints  each of Andre de Bruin and Timothy D.
Hoogheem, his/her true and lawful attorney-in-fact and agent, with full power of
substitution  and  resubstitution,  for him/her and in his/her  name,  place and
stead,  in any and all  capacities,  to sign any and all  amendments  (including
post-effective amendments) to this Registration Statement, and to file the same,
with all exhibits thereto, and other documents in connection therewith, with the
Securities and Exchange  Commission,  granting unto said  attorneys-in-fact  and
agents,  and each of them,  full power and  authority to do and perform each and
every act and thing requisite and necessary to be done in connection  therewith,
as fully to all intents and  purposes as he might or could do in person,  hereby
ratifying and confirming all that said  attorneys-in-fact  and agents, or any of
them, or their or his substitutes or substitute,  may lawfully do or cause to be
done by virtue hereof.

         Pursuant  to the  requirements  of the  Securities  Act of  1933,  this
Registration  Statement  has  been  signed  by  the  following  persons  in  the
capacities and on the dates indicated.

<TABLE>
<CAPTION>

Signature              Title                                  Date
- ---------              -----                                  ----
<S>                    <C>                                    <C>

Andre de Bruin         Chairman of the Board, President,      November 7, 1997
- -------------------    Chief Executive Officer
                       (Principal executive officer)

Timothy D. Hoogheem    Senior Vice President of Finance and   November 7, 1997
- -------------------    and Administration, Chief Financial
                       Officer, Treasurer and Assistant
                       Secretary (Principal financial officer)

Conrad A. McCarty      Corporate Controller                   November 7, 1997
- -------------------    (Principal accounting officer)

</TABLE>

<PAGE> 6

<TABLE>
<CAPTION>

Signature                         Title                      Date
- ---------                         -----                      ----
<S>                               <C>                        <C>

Carlos A. Ferrer                  Director                   November 7, 1997
- ---------------------------


Bernadine Healy, M.D.             Director                   November 7, 1997
- ---------------------------


Gene I. Miller                    Director                   November 7, 1997
- ---------------------------


George B. Rathmann, Ph.D.         Director                   November 7, 1997
- ---------------------------


Jack W. Schuler                   Director                   November 7, 1997
- ---------------------------


Ralph Snyderman, M.D.             Director                   November 7, 1997
- ---------------------------


</TABLE>


<PAGE> 7



                               INDEX TO EXHIBITS


Exhibit
Number

  3.4*     Bylaws.
  4.1*     Certificate of Incorporation, as amended.
  4.5*     Specimen stock certificate.
  5.1      Opinion of Cooley Godward LLP.
 23.1      Consent of Price Waterhouse LLP, Independent Accountants.
 23.3      Consent of Cooley Godward LLP. Reference is made to Exhibit 5.1.
 24.1      Power of Attorney.  Reference is made to the signature page.
 10.78     Registrant's Amended and Restated Nonemployee Director Stock Option
           Plan.
 10.79     Registrant's Amended and Restated Consultants Stock Option Plan.

- -----------------------

*  Filed  as an  exhibit  to the  Form  S-1  Registration  Statement  (No.
   33-41229),  as amended through the date hereof, and incorporated herein
   by reference.






                                                            Exhibit 5.1


November 7, 1997


Somatogen, Inc.
2545 Central Avenue
Suite FD1
Boulder, Colorado  80301-2857

Ladies and Gentlemen:

You have  requested  our opinion with respect to certain  matters in  connection
with  the  filing  by  Somatogen,  Inc.  (the  "Registrant")  of a  Registration
Statement on Form S-8 (the  "Registration  Statement")  with the  Securities and
Exchange  Commission  covering  the  offering  of up to  200,000  shares  of the
Registrant's Common Stock, $.001 par value, pursuant to the Registrant's Amended
and Restated  Nonemployee  Director Stock Option Plan (the "Director  Plan") and
100,000 shares of the Registrant's Common Stock, $.001 par value pursuant to the
Registrant's   Amended  and   Restated   Consultants   Stock  Option  Plan  (the
"Consultants  Plan") (the  Director Plan and the  Consultants  Plan herein after
collectively referred to as the "Plans") (collectively the "Shares").

In connection with this opinion, we have (i) examined the Registration Statement
and the related  Prospectus,  and (ii) reviewed the Registrant's  Certificate of
Incorporation  and  Bylaws,  as  amended,  and such  other  documents,  records,
certificates,  memoranda and other  instruments  as we deem necessary as a basis
for this opinion.  We also have assumed the genuineness and  authenticity of all
documents  submitted  to us as  originals,  the  conformity  to originals of all
documents submitted to us as copies thereof,  and the due execution and delivery
of all  documents  where due execution  and delivery are a  prerequisite  to the
effectiveness thereof.

On the basis of the foregoing,  and in reliance  thereon,  we are of the opinion
that the  Shares,  when  issued  and sold in  accordance  with  the  Plans,  the
Registration Statement and the related Prospectus, will be validly issued, fully
paid and nonassessable.

We  consent to the  filing of this  opinion  as an  exhibit to the  Registration
Statement.

Very truly yours,

Cooley Godward LLP



By:  James C.T. Linfield
   





                                                              EXHIBIT 23.1


            CONSENT OF PRICE WATERHOUSE LLP, INDEPENDENT ACCOUNTANTS


We  hereby  consent  to the  incorporation  by  reference  in  the  Registration
Statement on Form S-8 of Somatogen,  Inc. pertaining to the Amended and Restated
Nonemployee  Director Stock Option Plan and the Amended and Restated Consultants
Stock  Option Plan of our report  dated July 25, 1997  appearing  on Page F-1 of
Somatogen, Inc.'s Annual Report on Form 10-K for the year ended June 30, 1997.


PRICE WATERHOUSE LLP


Boulder, Colorado
November 5, 1997






                                                     
                                                                Exhibit 10.78

                                 SOMATOGEN, INC.

                              AMENDED AND RESTATED
                      NONEMPLOYEE DIRECTOR STOCK OPTION PLAN

                              ADOPTED JULY 13, 1993
                        AMENDED AND RESTATED JULY 22, 1997

1.       Purpose.

         The Somatogen,  Inc.  Amended and Restated  Nonemployee  Director Stock
Option Plan (the "Plan")  provides for the grant of Stock Options to Nonemployee
Directors of Somatogen,  Inc. (the  "Company") in order to advance the interests
of  the  Company  through  the  motivation,  attraction  and  retention  of  its
Nonemployee Directors.  This Plan is amended and restated to increase the number
of shares  reserved for  issuance,  to conform to the  provisions  of Rule 16b-3
under the Securities Exchange Act of 1934 and to permit Nonemployee Directors to
exchange their directors' fees for discounted stock options.

2.       NON-STATUTORY STOCK OPTIONS.

         The Stock Options  granted under the Plan shall be  nonstatutory  stock
options  ("NSOs")  which are  intended  to be  options  that do not  qualify  as
"incentive  stock  options"  under  Section 422 of the Internal  Revenue Code of
1986, as amended (the "Code").

3.       ADMINISTRATION.

         3.1 Committee. The Plan shall be administered by the Board of Directors
of the Company  (the  "Board") or by a committee of two or more  directors  (the
"Committee") if the Board delegates administration of the Plan to the Committee.
The  Committee or the Board,  as the case may be,  shall have full  authority to
administer the Plan, including authority to interpret and construe any provision
of the Plan and any Stock Option granted thereunder, and to adopt such rules and
regulations  for  administering  the Plan as it may deem  necessary  in order to
comply  with  the  requirements  of the  Code  or in  order  to  conform  to any
regulation or to any change in any law or  regulation  applicable  thereto.  The
Board of  Directors  may reserve to itself any of the  authority  granted to the
Committee  as set forth  herein,  and it may  perform and  discharge  all of the
functions  and  responsibilities  of  the  Committee  at  any  time  that a duly
constituted  Committee is not appointed and serving. All references in this Plan
to the "Committee"  shall be deemed to refer to the Board of Directors  whenever
the Board is discharging the powers and responsibilities of the Committee.

         3.2 Actions of Committee. All actions taken and all interpretations and
determinations made by the Committee in good faith (including  determinations of
Fair Market Value) shall be final and binding upon all Participants, the Company
and all other interested persons. No member of the Committee shall be personally
liable for any action,  determination or interpretation  made in good faith with
respect to the Plan,  and all  members of the  Committee  shall,  in addition to
their rights as directors, be fully protected by the Company with respect to any
such action, determination or interpretation.

<PAGE> 2

4.       DEFINITIONS.

         4.1 "Change in  Control." A Change in Control  occurs if (i) any person
(as such term is used in  Sections  23(d) and  14(d)(2)  of the  Securities  and
Exchange Act of 1934 (the "Exchange  Act")),  other than the Corporation,  is or
becomes the beneficial  owner (as defined in Rule 13D-3 under the Exchange Act),
directly  or  indirectly,  of 50% or more of the  combined  voting  power of the
outstanding  shares  of  capital  stock  of the  Corporation  entitled  to  vote
generally in the election of directors  (calculated as provided in Rule 13d-3(d)
under the Exchange Act in the case of rights to acquire capital stock),  whether
by means of a tender offer or exchange offer,  Transaction or otherwise; or (ii)
the  Board or the  stockholders  of the  Corporation  approve a  Transaction.  A
"Transaction"  is: (a) any consolidation or merger of the Corporation other than
a merger solely to effect a reincorporation or a merger of the Corporation as to
which stockholder approval is not required pursuant to Sections 251(f) or 253 of
the Delaware General Corporation Law; or (b) any sale, lease,  exchange or other
transfer (in one transaction or a series of related transactions) of 50% or more
of the assets of the  Corporation;  or (c) the  adoption of any plan or proposal
for the liquidation or dissolution of the Corporation.

         4.2 "Common Stock." A share of Common Stock means a share of authorized
by  unissued  or  reacquired  Common  Stock (par  value  $.001 per share) of the
Company.

         4.3 "Fair Market  Value." Fair Market Value means,  as of any date, the
value of the Common Stock of the Company determined as follows:

                  i. If the  Common  Stock is  listed on any  established  stock
exchange or traded on the Nasdaq  National  Market System or the Nasdaq SmallCap
Market,  the fair market  value of a share of Common  Stock shall be the closing
sales  price  for such  Common  Stock  (or the  closing  bid,  if no sales  were
reported)  as quoted on such  exchange or market (or the exchange or market with
the greatest  volume of trading in the Company's  Common Stock in the event that
the  Company's  Common Stock is traded on more than one such exchange or market)
on the day of  determination,  as reported  in The Wall  Street  Journal or such
other source as the Board deems reliable; or

                  ii. In the absence of such markets for the Common  Stock,  the
fair  market  value  shall be  determined  in good faith by the Board.  The Fair
Market  Value of a share of  Common  Stock on any date  shall be the  officially
quoted closing sale price on the Nasdaq  National Market on the date in question
or, in the absence of such markets for the Common  Stock,  the fair market value
shall be determined in good faith by the Board.

<PAGE> 3

         4.4 "Nonemployee  Director." A Nonemployee  Director is a Member of the
Board of Directors of the Company who is not also an employee of the Company.

         4.5  "Participant."  A Participant is a Nonemployee  Director to whom a
Stock Option is granted.

         4.6 "Stock  Option." A Stock Option is the right granted under the Plan
to a Nonemployee  Director to purchase,  at such time or times and at such price
or prices ("Option Price") as are determined pursuant to the Plan, the number of
shares of Common Stock determined pursuant to the Plan.

5.       AUTOMATIC STOCK OPTION GRANTS

         5.1  Initial  Grant.  On the  date  of  election  as a  Director,  each
Nonemployee  Director shall be granted a Stock Option to Purchase  15,000 shares
of common stock  (subject to  adjustment  pursuant to Section 7.2  hereof).  Any
Nonemployee  Director who is  prohibited  by a policy of his/her  employer  from
receiving  stock  options  under the Plan will not be eligible to receive  stock
options under this Plan.

         5.2 Annual  Grant.  Options were  granted  under this Plan prior to the
date of the Annual Meeting of  Stockholders  in 1997 under the terms of the Plan
in effect prior to this amendment and  restatement.  No automatic  annual grants
shall be made under this Plan at the Annual Meeting of Stockholders in 1997.

         At each  Annual  Meeting  of  Stockholders  commencing  in  1998,  each
Nonemployee Director who serves as a Director at such meeting shall be granted a
Stock  Option to  purchase  a number of shares  of Common  Stock  determined  by
multiplying  7,500 by a  fraction,  the  numerator  of which is $20.00,  and the
denominator  of which is the Fair Market  Value of one share of Common  Stock on
such date.  The number of shares  subject to each annual Stock Option grant will
not exceed 15,000 and will not be less than 7,500.  The foregoing  share numbers
and $20.00 figure will be proportionately adjusted to reflect the occurrence of 
any of the events referred to in Section 7.2.

         Notwithstanding  the  foregoing,  if the  number  of  shares  remaining
available for grant of Stock Options hereunder on the date of any Annual Meeting
of Stockholders is not sufficient to cover the foregoing  number of shares,  the
available  shares shall be allocated  ratably  among the  Nonemployee  Directors
eligible and receive a Stock Option on such date. Any  Nonemployee  Director who
is prohibited by a policy of his or her employer  from  receiving  Stock Options
under this Plan will not be eligible to receive Stock Options under the Plan.

<PAGE> 4

         5.3 Price.  The purchase price per share of Common Stock for the shares
to be  purchased  pursuant to the  exercise of any Stock Option shall be 100% of
the  Fair  Market  Value  of a share of  Common  Stock on the date on which  the
Nonemployee Director is granted the Stock Option.

         5.4 Other Terms.  Except for the  limitations set forth in Sections 5.1
and 5.2, the terms and  provisions of Stock Options shall be as determined  from
time to time by the  Committee,  and each Stock Option  issued may contain terms
and provisions  different from other Stock Options  granted to the same or other
Stock  Option  recipients.  Each Stock  Option  shall be  evidenced by a written
agreement  ("Option  Agreement")  containing  such terms and  provisions  as the
Committee may determine, subject to the provisions of the Plan.

         5.5 Time of  Exercise.  Stock  Options  shall  vest in equal  quarterly
installments  over a period of three years from grant and shall  expire,  to the
extent not exercised,  six years after the date of grant.  Stock Options granted
under the Plan,  including those granted prior to this amendment and restatement
of the Plan,  shall be fully vested and exercisable immediately  prior to the
consummation of a Change in Control.

         5.6 Six-Month  Holding  Period.  The shares of Common Stock issued upon
the exercise of a Stock  Option may not be sold or otherwise  disposed of within
six months after the date of grant of the Stock Option.

         5.7 Termination of Director Status Before Exercise.  If a Participant's
term as a director for the Company shall terminate for any reason other than the
Participant's   death  or  disability,   any  Stock  Option  then  held  by  the
Participant,  to  the  extent  then  exercisable  under  the  applicable  Option
Agreement(s),  shall remain  exercisable  after the  termination of his director
status for a period of three  months (but in no event  beyond six years from the
date of grant of the Stock  Option).  If the  Participant's  director  status is
terminated  because the  Participant  dies or is disabled  within the meaning of
Section 22(e)(3) of the Code, any Stock Option then held by the Participant,  to
the extent then  exercisable  under the applicable  Option  Agreement(s),  shall
remain  exercisable  after the  termination  of his  employment  for a period of
twelve  months  (but in no event  beyond six years from the date of grant of the
Stock  Option).  If the Stock  Option is not  exercised  during  the  applicable
period,  it shall be deemed to have been  forfeited  and of no further  force or
effect.

<PAGE> 5
     
6.       DEFERRED DIRECTOR FEE GRANTS.

         6.1 Deferral of Directors' Fees. Each Nonemployee Director may elect to
apply all or any portion of the meeting fees  otherwise  payable in cash for his
or her service on the Board or a committee of the Board  ("Directors'  Fees") to
the  acquisition  of a Stock  Option  pursuant to the terms of this Section 6 (a
"Deferred Fee Option"). Such election must be filed with the Corporation's Chief
Financial  Officer prior to the effective  date of the Plan for the  Nonemployee
Director  to be granted a  Deferred  Fee  Option on the  effective  date of this
amendment and restatement, and before the Annual Meeting of Stockholders for the
Nonemployee  Director  to receive a  Deferred  Fee Option as of the date of each
such Annual Meeting of Stockholders.  The deferral election shall be irrevocable
until the Annual Meeting of Stockholders following the Deferred Fee Option grant
date.  Each  Nonemployee  Director  who  files  such  a  timely  election  shall
automatically be granted an option under this Section 6 on the effective date of
this amendment and  restatement of the Plan or the date of the Annual Meeting of
Stockholders following the submission of the election.

         Notwithstanding  the  foregoing,  if the  number  of  shares  remaining
available for grant of Stock  Options under the Plan is not  sufficient to cover
the grant of options  under  Section 6 and Deferred Fee Options,  the  available
shares shall be first  allocated to the Stock  Options  under Section 5 and then
ratably  among the  Nonemployee  Directors  eligible  and receive a Deferred Fee
Option based on their relative deferred fees.

         6.2 Price.  The purchase price per share of Common Stock for the shares
to be  purchased  pursuant to the  exercise of any  Deferred Fee Option shall be
33-1/3%  of the Fair  Market  Value of a share  of  Common  Stock on the date of
grant.

         6.3  Number  of Option  Shares.  The  number of shares of Common  Stock
subject to a Deferred Fee Option shall be  determined  pursuant to the following
formula (rounded down to the nearest whole number):

                  X = A / (B x 66-2/3%), where 
                  X is the number of option shares,
                  A is the maximum amount of the Director's Fees subject to the
                  Nonemployee Director's deferral election, and
                  B is the fair market value per share of Common Stock on the 
                  option grant date.
<PAGE> 6

         6.4 Vesting.  Each Deferred Fee Option shall vest (become  exercisable)
in  installments  on each date that  Directors'  Fees would have been payable in
cash had no deferral  election  been in effect under this Section 6 with respect
to the  number  of  shares  equal to (1) the  aggregate  shares  subject  to the
Deferred Fee Option  multiplied by (2) the fraction obtained where the numerator
is the cash Directors' Fees that the Nonemployee  Director  otherwise would have
received on such date and the denominator is the aggregate  Directors' Fees that
the Nonemployee  Director would have received in cash absent a deferral election
following the date of grant until the next Annual Meeting of Stockholders.  Each
Deferred Fee Option shall be fully vested and exercisable  immediately  prior to
the consummation of a Change in Control.  Solely for purposes of calculating the
vested  percentage of a Deferred Fee Option, a Nonemployee  Director who dies or
becomes  disabled  (within the meaning of Section  22(e)(3) of the Code) while a
director  shall be deemed to have earned,  as of the date of his or her death or
disability,  the maximum  Directors' Fees that he or she could have earned until
the next Annual Meeting of Stockholders.

         To the  extent a  Deferred  Fee  Option is not vested on the day of the
next Annual Meeting of  Stockholders  following the date of grant,  the Deferred
Fee Option shall be forfeited and the shares of Company common stock  underlying
such  Deferred Fee Option shall again be made subject to Stock Options under the
Plan.

         6.5 Termination of Director Status Before Exercise.  If a Participant's
term as a director for the Company  shall  terminate  for any reason,  any Stock
Option  then held by the  Participant,  to the extent  then  exercisable,  shall
remain  exercisable after the termination of his director status for a period of
three  years  (but in no event  beyond  six years  from the date of grant of the
Deferred Fee Option).  If the  Deferred Fee Option is not  exercised  during the
applicable  period,  it shall be deemed to have been forfeited and of no further
force or effect.

<PAGE> 7

7.       SHARES OF COMMON STOCK SUBJECT TO THE PLAN

         7.1 Maximum Number.  The maximum  aggregate  number of shares of Common
Stock that may be made subject to Stock Options shall be 470,000 authorized but
unissued shares.  If any shares of Common Stock subject to Stock Options are not
purchased or otherwise  paid for before such Stock Options  expire,  such shares
may again be made subject to Stock Options hereunder.

         7.2 Capital Changes. In the event any changes are made to the shares of
Common  Stock  (whether  by reason  of  merger,  consolidation,  reorganization,
recapitalization,  stock  dividend in excess of ten percent  (10%) at any single
time,  stock  split,  combination  of  shares,  exchange  of  shares,  change in
corporate structure or otherwise), appropriate adjustments shall be made in: (i)
the number of shares of Common Stock  theretofore made subject to Stock Options,
and in the  purchase  price of said  shares;  and (ii) the  aggregate  number of
shares  which may be made  subject  to Stock  Options.  If any of the  foregoing
adjustments   shall  result  in  a  fractional  share,  the  fraction  shall  be
disregarded,  and the Company shall have no obligation to make any cash or other
payment with respect to such a fractional share.

8.       NO EFFECT UPON STOCKHOLDER RIGHTS.

         Nothing in this Plan shall  interfere  in any way with the right of the
stockholders of the Company to remove the Participant from the Board pursuant to
the Delaware General  Corporation Law and the Company's Restated  Certificate of
Incorporation and Bylaws.

9.       NO RIGHTS AS A STOCKHOLDER.

         A Participant shall have no rights as a stockholder with respect to any
shares of Common Stock subject to a Stock Option.  Except as provided in Section
7.2, no adjustment  shall be made in the number of shares of Common Stock issued
to a Participant,  or in any other rights of the Participant  upon exercise of a
Stock Option, by reason of any dividend,  distribution or other right granted to
stockholders  for which the record  date is prior to the date of exercise of the
Participant's Stock Option.


<PAGE> 8


10.      ASSIGNABILITY.

         No Stock Option granted under this Plan, nor any other rights  acquired
by a  Participant  under this Plan,  shall be assignable  or  transferable  by a
Participant,  other  than by will or the laws of  descent  and  distribution  or
pursuant to a qualified domestic relations order as defined by the Code, Title I
of the  Employment  Retirement  Income  Security  Act  ("ERISA"),  or the  rules
thereunder.  In the event of the  Participant's  death,  the Stock Option may be
exercised by the Personal  Representative of the Participant's  estate or, if no
Personal  Representative  has been appointed,  by the successor or successors in
interest determined under the Participant's will or under the applicable laws of
descent and distribution.

11.      MERGER OR LIQUIDATION OF THE COMPANY.

         If the Company or its  stockholders  enter into an agreement to dispose
of all, or substantially all, of the assets or outstanding  capital stock of the
Company  by means of a sale or  liquidation,  or a merger or  reorganization  in
which the Company is not the surviving corporation, the Committee shall have the
power and  discretion to prescribe the terms and conditions for the exercise of,
or modification of, the Stock Options granted hereunder. By way of illustration,
and not by way of limitation,  the Committee may provide that such Stock Options
will be  exchanged  or  converted  into  options  to acquire  securities  of the
surviving or acquiring corporation, or may provide for a payment or distribution
in  respect  of  outstanding  Stock  Options  (or the  portion  thereof  that is
currently  exercisable) in cancellation  thereof. The Committee may provide that
Stock Options or other rights granted  hereunder must be exercised in connection
with the closing of such transaction,  and that if not so exercised such Options
will  expire.  The  provisions  of  this  Section  11  shall  not  apply  to any
transaction  undertaken for the purpose of reincorporating the Company under the
laws of another jurisdiction, if such transaction does not materially affect the
beneficial ownership of the Company's capital stock.

12.      AMENDMENT.

         The Board may from time to time alter,  amend,  suspend or  discontinue
the Plan,  including,  where  applicable,  any modifications or amendments as it
shall deem  advisable in order to conform to any  regulation or to change in any
law or regulation  applicable thereto;  provided,  however,  that no such action
shall adversely  affect the rights and obligations with respect to Stock Options
at any time outstanding under the Plan; and provided further that no such action
shall be taken  without the approval of the  stockholders  of the Company  where
such  approval  is  required  to  conform  to Nasdaq or stock  exchange  listing
requirements.


<PAGE> 9



13.      REGISTRATION OF OPTIONED SHARES.

         No shares of Common  Stock  will be  issuable  upon  exercise  of Stock
Options  unless  the  issuance  of such  shares  is  pursuant  to an  applicable
effective  registration  statement  under the Securities Act of 1933, as amended
(the "Act"), or unless,  in the opinion of counsel to the Company,  the issuance
of such shares would be exempt from the registration requirements of the Act and
from  the  registration  or  qualification   requirements  of  applicable  state
securities laws.

14.      BROKERAGE ARRANGEMENTS.

         The Committee, in its discretion,  may enter into arrangements with one
or more  banks,  brokers  or other  financial  institutions  to  facilitate  the
disposition of shares acquired upon exercise of Stock Options including, without
limitation, arrangements for the simultaneous exercise of Stock Options and sale
of the shares acquired upon such exercise.

15.      NONEXCLUSIVITY OF THE PLAN.

         Neither the adoption of the Plan by the Board nor the submission of the
Plan to  stockholders of the Company for approval shall be construed as creating
any  limitations  on the power or  authority of the Board to adopt such other or
additional  compensation  arrangements  of whatever nature as the Board may deem
necessary or desirable or preclude or limit the  continuation of any other plan,
practice or arrangement  for the payment of  compensation  or fringe benefits to
Nonemployee Directors, which the Company now has lawfully put into effect.

16.      EFFECTIVE DATE.

         This  amendment and  restatement  of the Plan shall be effective on the
date  established by the Board;  provided that this amendment and restatement of
the Plan is subject to the condition subsequent that the Plan is approved by the
stockholders of the Company.  In the event that the  stockholders of the Company
do not  approve the  amendment  and  restatement  of the Plan at the 1997 Annual
Meeting of Stockholders,  then (i) the increase in the number of shares reserved
for  issuance  hereunder  shall  be void and  (ii)  any  Nonemployee  Director's
election to defer  Directors'  Fees  hereunder  shall be void, and such deferred
Directors'  Fees shall be paid in cash to such  Nonemployee  Director as soon as
reasonably practicable following the 1997 Annual Meeting of Stockholders.




                                                                  Exhibit 10.79


                                 SOMATOGEN, INC.
                              AMENDED AND RESTATED
                          CONSULTANTS STOCK OPTION PLAN

                              ADOPTED JUNE 15, 1995
                      AMENDED AND RESTATED OCTOBER 28, 1997

1.       PURPOSES.

         (a) The  purpose  of the Plan is to  provide a means by which  selected
Consultants to the Company,  and its Affiliates,  may be given an opportunity to
purchase stock of the Company.

         (b) The Company,  by means of the Plan, seeks to retain the services of
persons who are now Consultants to the Company or its Affiliates,  to secure and
retain the  services  of new  Consultants,  and to provide  incentives  for such
persons  to  exert  maximum  efforts  for the  success  of the  Company  and its
Affiliates.

         (c) Options issued under the Plan shall be  nonstatutory  stock options
(i.e.,  Options that do not qualify as incentive stock options under Section 422
of the Code).

2.       DEFINITIONS.

         (a) "Affiliate" means any parent corporation or subsidiary corporation,
whether now or hereafter existing, as those terms are defined in Sections 424(e)
and (f) respectively, of the Code.

         (b) "Board" means the Board of Directors of the Company.

         (c) "Code" means the Internal Revenue Code of 1986, as amended.

         (d) "Committee" means a Committee  appointed by the Board in accordance
with subsection 3(c) of the Plan.

         (e) "Company" means Somatogen, Inc., a Delaware corporation.

         (f) "Consultant"  means any person,  including a scientific or clinical
advisor,  engaged by the Company or an Affiliate to render  consulting  services
and who is compensated  for such services,  provided that the term  "Consultant"
shall not include Directors who are paid only a director's fee by the Company or
who are not compensated by the Company for their services as Directors.

         (g)  "Continuous  Status as a Consultant"  means the  relationship as a
Consultant is not interrupted or terminated.  The Board, in its sole discretion,
may  determine  whether  Continuous  Status as a Consultant  shall be considered
interrupted  in the case of:  (i) any leave of  absence  approved  by the Board,
including  sick leave,  military  leave,  or any other personal  leave;  or (ii)
transfers between locations of the Company or between the Company, Affiliates or
their successors.

<PAGE> 2

         (h)  "Director" means a member of the Board.

         (i)  "Employee"  means any person,  including  Officers and  Directors,
employed by the Company or any  Affiliate of the Company.  Neither  service as a
Director nor payment of a director's  fee by the Company  shall be sufficient to
constitute "employment" by the Company.

         (j)  "Exchange  Act"  means the  Securities  Exchange  Act of 1934,  as
amended.

         (k) "Fair Market Value" means,  as of any date, the value of the common
stock of the Company determined as follows:

                  (i) If the  common  stock is listed on any  established  stock
exchange or a national market system,  including without limitation the National
Market System of the National Association of Securities Dealers,  Inc. Automated
Quotation  ("NASDAQ")  System,  the Fair Market Value of a share of common stock
shall be the closing sales price for such stock (or the closing bid, if no sales
were  reported) as quoted on such system or exchange  (or the exchange  with the
greatest volume of trading in common stock) on the last market trading day prior
to the day of  determination,  as reported  in the Wall  Street  Journal or such
other source as the Board deems reliable;

                  (ii) If the common  stock is quoted on the NASDAQ  System (but
not  on  the  National  Market  System  thereof)  or is  regularly  quoted  by a
recognized  securities  dealer but  selling  prices are not  reported,  the Fair
Market  Value of a share of common  stock shall be the mean  between the bid and
asked  prices for the common  stock on the last market  trading day prior to the
day of  determination,  as  reported  in the Wall  Street  Journal or such other
source as the Board deems reliable;

                  (iii) In the absence of an  established  market for the common
stock, the Fair Market Value shall be determined in good faith by the Board.

         (l)  "Officer"  means a person who is an officer of the Company  within
the  meaning  of Section 16 of the  Exchange  Act and the rules and  regulations
promulgated thereunder.

         (m) "Option" means a stock option granted pursuant to the Plan.

         (n) "Option  Agreement" means a written  agreement  between the Company
and an Optionee  evidencing  the terms and  conditions of an  individual  Option
grant. Each Option Agreement shall be subject to the terms and conditions of the
Plan.

         (o) "Optionee" means a Consultant who holds an outstanding Option.

         (p) "Plan" means this Somatogen, Inc. Amended and Restated Consultants 
Stock Option Plan.

         (q) "Rule 16b-3" means Rule 16b-3 of the Exchange Act or any  successor
to Rule 16b-3,  as in effect when  discretion is being exercised with respect to
the Plan.

<PAGE> 3

3.       ADMINISTRATION.

         (a) The Plan shall be  administered  by the Board  unless and until the
Board delegates administration to a Committee, as provided in subsection 3(c).

         (b) The  Board  shall  have the  power,  subject  to,  and  within  the
limitations of, the express provisions of the Plan:

                 (i) To  determine  from  time  to  time  which  of the  persons
eligible under the Plan shall be granted Options; when and how each Option shall
be granted; the provisions of each Option granted (which need not be identical),
including  the time or times such Option may be  exercised  in whole or in part;
and the  number of shares  for which an  Option  shall be  granted  to each such
person.

                 (ii) To construe  and  interpret  the Plan and Options  granted
under it, and to  establish,  amend and  revoke  rules and  regulations  for its
administration.  The Board,  in the  exercise  of this  power,  may  correct any
defect,  omission or inconsistency in the Plan or in any Option Agreement,  in a
manner and to the extent it shall deem  necessary  or expedient to make the Plan
fully effective.

                 (iii) To amend the Plan or an Option as provided in Section 11.

                 (iv)  Generally,  to exercise  such powers and to perform  such
acts as the Board deems  necessary or expedient to promote the best interests of
the Company.

         (c) The Board may  delegate  administration  of the Plan to a committee
composed  of not fewer than one (1) member of the Board  (the  "Committee").  If
administration  is  delegated  to a  Committee,  the  Committee  shall have,  in
connection with the administration of the Plan, the powers theretofore possessed
by the Board (and  references  in this Plan to the Board shall  thereafter be to
the Committee), subject, however, to such resolutions, not inconsistent with the
provisions  of the Plan,  as may be adopted from time to time by the Board.  The
Board  may  abolish  the  Committee  at any time and  revest  in the  Board  the
administration of the Plan.

4.       SHARES SUBJECT TO THE PLAN.

         (a) Subject to the  provisions  of Section 10  relating to  adjustments
upon changes in stock,  the stock that may be sold pursuant to Options shall not
exceed in the  aggregate one hundred  eighty  thousand  (180,000)  shares of the
Company's  common stock.  If any Option shall for any reason expire or otherwise
terminate, in whole or in part, without having been exercised in full, the stock
not purchased  under such Option shall revert to and again become  available for
issuance under the Plan.

         (b) The stock subject to the Plan may be unissued  shares or reacquired
shares, bought on the market or otherwise.


<PAGE> 4

5.       ELIGIBILITY.

         Consultants  to  the  Company  are  eligible  to  receive  Options
hereunder. No Options may be granted under this Plan to any person who is at the
time of such grant an Officer, Director or Employee of the Company.

6.       OPTION PROVISIONS.

         Each  Option  shall be in such form and shall  contain  such  terms and
conditions  as the Board  shall deem  appropriate.  The  provisions  of separate
Options  need  not  be  identical,   but  each  Option  shall  include  (through
incorporation of provisions  hereof by reference in the Option or otherwise) the
substance of each of the following provisions:

         (a) Term. No Option shall be  exercisable  after the  expiration of ten
(10) years from the date it was granted.

         (b) Price. The exercise price of each Option shall be not less than one
hundred  percent  (100%) of the Fair  Market  Value of the stock  subject to the
Option on the date the Option is granted.

         (c) Consideration.  The purchase price of stock acquired pursuant to an
Option  shall be paid,  to the  extent  permitted  by  applicable  statutes  and
regulations,  either (i) in cash at the time the Option is exercised, or (ii) at
the  discretion of the Board or the  Committee,  at the time of the grant of the
Option, (A) by delivery to the Company of other common stock of the Company, (B)
according to a deferred payment or other arrangement (which may include, without
limiting the generality of the  foregoing,  the use of other common stock of the
Company)  with the person to whom the Option is granted or to whom the Option is
transferred  pursuant  to  subsection  6(d),  or (C) in any other  form of legal
consideration that may be acceptable to the Board.

         (d) Transferability. An Option shall not be transferable except by will
or by the laws of descent and distribution,  and shall be exercisable during the
lifetime of the person to whom the Option is granted  only by such  person.  The
person to whom the Option is granted may, by  delivering  written  notice to the
Company, in a form satisfactory to the Company,  designate a third party who, in
the event of the death of the Optionee, shall thereafter be entitled to exercise
the Option.

         (e) Vesting.  The total number of shares of stock  subject to an Option
may,  but need not, be allotted in periodic  installments  (which may,  but need
not, be equal).  The Option  Agreement may provide that from time to time during
each of such installment  periods,  the Option may become  exercisable  ("vest")
with respect to some or all of the shares  allotted to that  period,  and may be
exercised  with  respect to some or all of the shares  allotted  to such  period
and/or any prior period as to which the Option  became  vested but was not fully
exercised.  The Option may be subject to such other terms and  conditions on the
time or times when it may be  exercised  (which may be based on  performance  or
other criteria) as the Board may deem appropriate.

<PAGE> 5

         (f) Securities Law Compliance. The Company may require any Optionee, or
any  person  to whom an  Option  is  transferred  under  subsection  6(d),  as a
condition  of  exercising  any  such  Option,  (1) to  give  written  assurances
satisfactory  to the Company as to the  Optionee's  knowledge and  experience in
financial  and  business  matters  and/or to employ a  purchaser  representative
reasonably  satisfactory to the Company who is knowledgeable  and experienced in
financial  and business  matters,  and that he or she is capable of  evaluating,
alone or together  with the  purchaser  representative,  the merits and risks of
exercising the Option;  and (2) to give written  assurances  satisfactory to the
Company  stating that such person is acquiring  the stock  subject to the Option
for such  person's own account and not with any present  intention of selling or
otherwise distributing the stock. The foregoing requirements, and any assurances
given pursuant to such requirements, shall be inoperative if (i) the issuance of
the shares  upon the  exercise  of the Option has been  registered  under a then
currently effective  registration statement under the Securities Act of 1933, as
amended (the  "Securities  Act"),  or (ii) as to any particular  requirement,  a
determination  is made by counsel for the Company that such requirement need not
be met in the  circumstances  under the then  applicable  securities  laws.  The
Company  may,  upon  advice of counsel to the  Company,  place  legends on stock
certificates   issued  under  the  Plan  as  such  counsel  deems  necessary  or
appropriate in order to comply with applicable securities laws,  including,  but
not limited to, legends restricting the transfer of the stock.

         (g)  Termination  of  Relationship  as a  Consultant.  In the  event an
Optionee's  Continuous  Status as an Consultant  terminates (other than upon the
Optionee's death or disability), the Optionee may exercise his or her Option (to
the  extent  that  the  Optionee  was  entitled  to  exercise  it at the date of
termination)  but only  within  such period of time ending on the earlier of (i)
the date three (3) months after the  termination  of the  Optionee's  Continuous
Status as a Consultant,  or (ii) the expiration of the term of the Option as set
forth in the Option  Agreement.  If, after  termination,  the Optionee  does not
exercise his or her Option  within the time  specified in the Option  Agreement,
the Option shall  terminate,  and the shares covered by such Option shall revert
to and again become available for issuance under the Plan.

         (h)  Disability  of  Optionee.  In the event an  Optionee's  Continuous
Status as a Consultant terminates as a result of the Optionee's disability,  the
Optionee  may  exercise  his or her Option (to the extent that the  Optionee was
entitled to exercise it at the date of termination), but only within such period
of time ending on the earlier of (i) the date twelve (12) months  following such
termination or (ii) the expiration of the term of the Option as set forth in the
Option Agreement.  If, at the date of termination,  the Optionee is not entitled
to exercise his or her entire Option,  the shares  covered by the  unexercisable
portion of the Option shall revert to and again  become  available  for issuance
under the Plan. If, after termination, the Optionee does not exercise his or her
Option within the time specified  herein,  the Option shall  terminate,  and the
shares  covered by such Option shall revert to and again  become  available  for
issuance under the Plan.

<PAGE> 6

         (i) Death of Optionee. In the event of the death of an Optionee during,
or within a period  specified  in the  Option  after  the  termination  of,  the
Optionee's  Continuous  Status as a Consultant,  the Option may be exercised (to
the extent the  Optionee  was  entitled  to  exercise  the Option at the date of
death) by the Optionee's  estate, by a person who acquired the right to exercise
the Option by bequest or inheritance  or by a person  designated to exercise the
option upon the Optionee's  death  pursuant to subsection  6(d), but only within
the period  ending on the earlier of (i) the date  twelve (12) months  following
the date of  death,  or (ii) the  expiration  of the term of such  Option as set
forth in the Option  Agreement.  If, at the time of death,  the Optionee was not
entitled  to  exercise  his or her  entire  Option,  the  shares  covered by the
unexercisable  portion of the Option shall revert to and again become  available
for issuance under the Plan. If, after death, the Option is not exercised within
the time specified herein, the Option shall terminate, and the shares covered by
such Option shall revert to and again become  available  for issuance  under the
Plan.

         (j) Early Exercise.  The Option may, but need not,  include a provision
whereby the Optionee  may elect at any time while a  Consultant  to exercise the
Option as to any part or all of the shares  subject  to the Option  prior to the
full vesting of the Option. Any unvested shares so purchased may be subject to a
repurchase  right in favor of the Company or to any other  restriction the Board
determines to be appropriate.

         (k)  Withholding.  To the  extent  provided  by the  terms of an Option
Agreement,  the Optionee may satisfy any federal, state or local tax withholding
obligation relating to the exercise of such Option by any of the following means
or by a combination of such means: (1) tendering a cash payment; (2) authorizing
the Company to withhold  shares  from the shares of the common  stock  otherwise
issuable to the  participant  as a result of the exercise of the Option;  or (3)
delivering to the Company owned and  unencumbered  shares of the common stock of
the Company.

7.       COVENANTS OF THE COMPANY.

         (a) During the terms of the Options,  the Company shall keep  available
at all times the number of shares of stock required to satisfy such Options.

         (b) The Company shall seek to obtain from each regulatory commission or
agency having  jurisdiction  over the Plan such  authority as may be required to
issue and sell shares of stock upon exercise of the Options; provided,  however,
that this  undertaking  shall not  require  the  Company to  register  under the
Securities  Act either  the Plan,  any  Option or any stock  issued or  issuable
pursuant to any such Option. If, after reasonable efforts, the Company is unable
to obtain from any such  regulatory  commission  or agency the  authority  which
counsel for the Company  deems  necessary  for the lawful  issuance  and sale of
stock under the Plan,  the  Company  shall be relieved  from any  liability  for
failure to issue and sell stock upon  exercise of such Options  unless and until
such authority is obtained.

8.       USE OF PROCEEDS FROM STOCK.

         Proceeds from the sale of stock  pursuant to Options  shall  constitute
general funds of the Company.

<PAGE> 7

9.       MISCELLANEOUS.

         (a) The Board shall have the power to  accelerate  the time at which an
Option may first be  exercised  or the time  during  which an Option or any part
thereof will vest pursuant to subsection 6(e), notwithstanding the provisions in
the  Option  stating  the time at which it may  first be  exercised  or the time
during which it will vest.

         (b) Neither an Optionee nor any person to whom an Option is transferred
under subsection 6(d) shall be deemed to be the holder of, or to have any of the
rights of a holder with respect to, any shares subject to such Option unless and
until such person has  satisfied  all  requirements  for  exercise of the Option
pursuant to its terms.

         (c) Nothing in the Plan or any  instrument  executed or Option  granted
pursuant  thereto  shall  confer upon any  Consultant  or Optionee  any right to
continue in to continue  acting as a Consultant or shall affect the right of the
Company or any  Affiliate to terminate the  relationship  as a Consultant of any
Consultant or Optionee with or without cause.

10.      ADJUSTMENTS UPON CHANGES IN STOCK.

         (a)  In the  event  of:  (1) a  dissolution,  liquidation  or  sale  of
substantially all of the assets of the Company; (2) a merger or consolidation in
which the Company is not the surviving  corporation;  or (3) a reverse merger in
which the Company is the surviving  corporation  but the shares of the Company's
common  stock  outstanding  immediately  preceding  the merger are  converted by
virtue of the merger  into other  property,  whether in the form of  securities,
cash or  otherwise,  then to the extent  permitted  by  applicable  law: (i) any
surviving  corporation  shall assume any Options  outstanding  under the Plan or
shall substitute  similar Options for those  outstanding under the Plan, or (ii)
such Options shall continue in full force and effect. In the event any surviving
corporation refuses to assume or continue such Options, or to substitute similar
options for those outstanding under the Plan, then, with respect to Options held
by persons then performing  services as Consultants,  the time during which such
Options may be exercised shall be accelerated and the Options  terminated if not
exercised prior to such event.

         (b) If any change is made in the stock  subject to the Plan, or subject
to any Option (through merger, consolidation, reorganization,  recapitalization,
stock dividend,  dividend in property other than cash, stock split,  liquidating
dividend,  combination  of  shares,  exchange  of  shares,  change in  corporate
structure or other transaction not involving the receipt of consideration by the
Company),  the Plan will be  appropriately  adjusted  in the type(s) and maximum
number of securities  subject to the Plan pursuant to subsection  4(a),  and the
outstanding Options will be appropriately adjusted in the types(s) and number of
securities  and price per share of stock  subject to such  outstanding  Options.
Such adjustments  shall be made by the Board or Committee,  the determination of
which shall be final, binding and conclusive. (The conversion of any convertible
securities of the Company shall not be treated as a  "transaction  not involving
the receipt of consideration by the Company.")

<PAGE> 8

11.      AMENDMENT OF THE PLAN AND OPTIONS.

         (a) The Board at any time, and from time to time, may amend the Plan.

         (b) The Board may in its sole discretion  submit any other amendment to
the Plan for stockholder approval.

         (c) Rights and obligations under any Option granted before amendment of
the Plan  shall not be  impaired  by any  amendment  of the Plan  unless (i) the
Company  requests  the  consent of the person to whom the Option was granted and
(ii) such person consents in writing.

         (d) The Board at any time,  and from time to time,  may amend the terms
of any one or more Options;  provided,  however, that the rights and obligations
under any Option  shall not be  impaired  by any such  amendment  unless (i) the
Company  requests  the  consent of the person to whom the Option was granted and
(ii) such person consents in writing.

12.      TERMINATION OR SUSPENSION OF THE PLAN.

         (a) The Board may  suspend or  terminate  the Plan at any time.  Unless
sooner terminated,  the Plan shall terminate on June 14, 2005. No Options may be
granted under the Plan while the Plan is suspended or after it is terminated.

         (b) Rights and  obligations  under any Option granted while the Plan is
in effect shall not be impaired by suspension or termination of the Plan, except
with the consent of the person to whom the Option was granted.

13.      EFFECTIVE DATE OF PLAN.

         This  amendment and  restatement  of the Plan shall be effective on the
date established by the Company's Board of Directors.



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