MERRILL LYNCH OHIO MUNICIPAL BOND FUND OF
               MERRILL LYNCH MULTI-STATE MUNICIPAL SERIES TRUST

                    SUPPLEMENT DATED SEPTEMBER 25, 1997 TO
                      PROSPECTUS DATED NOVEMBER 15, 1996

     The third  paragraph under  "Management of the  Trust --  Management and
Advisory  Arrangements,"  which  provides  the  name  and  biography  of  the
portfolio manager of the Fund, is revised as follows:

     Theodore R.  Jaeckel, Jr. is  the Portfolio Manager  of the Fund  and is
responsible for the day-to-day management of the Fund's investment portfolio.
He has been  a Director of MLAM since  1997 and was a  Vice President thereof
from 1991 to 1997.

Code #16154-1196ALL



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