PRICE T ROWE SCIENCE & TECHNOLOGY FUND INC
N-30D, 1995-02-02
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Annual Report                                                                  
                                                                               
                                                                               
<PAGE>                                                                       
                                                                               
                                                                               
[Logo]                                                                         
Science and                                                                    
Technology Fund                                                                
                                                                               
December 31, 1994                                                              
                                                                               
                                                                               
FOR YIELD, PRICE, LAST TRANSACTION, AND CURRENT BALANCE, 24 HOURS,             
7 DAYS A WEEK, CALL:                                                           
1-800-638-2587 toll free                                                       
625-7676 Baltimore area                                                        
                                                                               
FOR ASSISTANCE WITH YOUR EXISTING FUND ACCOUNT, CALL:                          
Shareholder Service Center                                                     
1-800-225-5132 toll free                                                       
625-6500 Baltimore area                                                        
                                                                               
T. ROWE PRICE                                                                  
100 East Pratt Street                                                          
Baltimore, Maryland 21202                                                      
                                                                               
This report is authorized for distri-bution only to shareholders and to others 
who  have  received  a copy of the prospectus of the T. Rowe Price Science and 
Technology Fund.                                                               
                                                                               
                                                                               
[Logo]                                                                         
STF                                                                            
                                                                               
                                                                               
<PAGE>                                                                       
                                                                               
                                                                               
Fellow Shareholders                                                            
                                                                               
The  Science  &  Technology  Fund  enjoyed another year of strong performance. 
Following  a  difficult  first  half,  during which the sector experienced its 
first quarterly declines since the second quarter of 1992, your Fund generated 
superior  returns  in  the  second  half. The results were consistent with our 
longer-term  operating objective of staying close to the averages in difficult 
markets while providing strong returns in more favorable environments. For the 
fourth  quarter  and  the  year, your Fund significantly outperformed both the 
unmanaged  Standard  &  Poor's 500 Stock Index and the Lipper Index of similar 
funds.                                                                         
                                                                               
Performance Comparison                                                         
                                                                               
                                   Periods Ended                               
                                     12/31/94                                  
                                 3 Months 12 Months                            
                                --------- ---------                            
Science & Technology Fund            8.8%     15.8%                            
S&P 500                               0.0       1.3                            
Lipper Science & Technology                                                    
  Fund Index                          5.3      10.3                            
- ---------------------------------------------------                            
                                                                               
    Our  commitment  to  building value over the long term is evidenced by the 
Fund's  cumulative  return of 170% for the five-year period ended December 31, 
1994.  For  the  third consecutive year, your Fund's five-year performance has 
ranked  among the top 25 equity funds in the country1. We will work diligently 
to extend this record.                                                         
                                                                               
/1/According  to Lipper Analytical Services, the Fund's ranking based on total 
return  since  inception  (9/30/87)  and for five- and one-year periods ending 
12/31/94 was 4 out of 784, 10 out of 1,028, and 26 out of 2,366, respectively. 
See  page  4  for  the  Fund's  average  annual  compound  total  return. Past 
performance cannot guarantee future results.                                   
                                                                               
CAPITAL GAIN DISTRIBUTION                                                      
Your  Board  of  Directors  declared  a capital gain distribution of $0.30 per 
share  for  1994.  This  distribution,  payable December 29 to shareholders of 
record  on  December  27,  reflected  a short-term capital gain of $0.10 and a 
long-term  capital  gain of $0.20. Given the potential for a capital gains tax 
cut  in 1995, we are pleased that our 1994 distribution was modest relative to 
the  Fund's  return.  Your  check or statement reflecting the distribution was 
mailed  in  early January, and Form 1099-DIV, with additional tax information, 
was mailed toward month-end.                                                   
                                                                               
MARKET ENVIRONMENT                                                             
Nineteen ninety-four was a difficult year for both the bond and stock markets. 
Factors  pressuring  the  financial  markets  included  rising interest rates, 
slowing  inflows  into  mutual  funds, investor nervousness over the misuse of 
derivative securities, political unrest in Eastern Europe and the Mideast, the 
bankruptcy  of Orange County, California, and the year-end financial crisis in 
Mexico.  Science  and  technology  stocks  in  particular were affected by the 
Clinton   administration's   failure  to  pass  key  health  care  reform  and 
telecommunications legislation.                                                
    During the year, the Federal Reserve raised the federal funds rates in six 
steps  from 3.0% to 5.5% and the discount rate three times from 3.0% to 4.75%. 
Not  only  did  these  interest rate increases result in one of the worst bond 
markets  in  modern memory, but stocks of interest rate-sensitive sectors such 
as   utilities   and  financial  services  also  suffered  appreciably.  While 
traditionally  conservative  investment categories were hit hardest, few asset 
classes  were  spared,  and  most  groups  provided  disappointing returns. As 
interest  rates  rose,  money flows into mutual funds weakened, removing a key 
driver  of  stock  market gains-liquidity. The combination of rising rates and 
slowing demand from mutual funds put downward pressure on stock valuations.    
    Entering  1994,  science  and  technology  investors anxiously anticipated 
reform  legislation in both health care and telecommunications. Unfortunately, 
Congress-like  major  league  baseball-could  not  reach  an agreement, and no 
legislation  was  passed  in  either area. Although the failure of health care 
reform   was   probably   a   positive   for   that  sector,  the  failure  of 
telecommunications  legislation  lowered  the  speed  limit on the information 
superhighway and left standing the roadblocks faced by all participants.       
                                                                               
                                                                               
<PAGE>                                                                       
                                                                               
                                                                               
    The  irony  of 1994 was that normally conservative investments experienced 
the  worst  losses  while  the aggressive science and technology sector had an 
outstanding  year.  Investors  with large holdings in bonds and utility stocks 
suffered  a  slow  bleed  in  asset  value,  but science and technology stocks 
recovered  sharply  from  their June lows to post excellent returns. The table 
below  summarizes  the  relative performance of the various Dow Jones Industry 
Groups,  highlighting  the  strong  performance  of the science and technology 
sector during 1994.                                                            
                                                                               
Index                           1994 Return                                    
- ------------------------------- -----------                                    
Technology: Electronics/                                                       
  Medical-Technology                  12.5%                                    
Consumer Non-Cyclical                  8.1                                    
Basic Materials                        3.0                                    
Energy                                -1.3                                    
Conglomerates                         -2.7                                    
Financial                             -6.6                                    
Industrial                            -7.6                                    
Consumer Cyclical                    -10.7                                    
Utilities                            -13.7                                    
                                                                               
    Several  factors  drove  science and technology stocks to record levels in 
1994. Most important, business remained strong throughout the year: demand was 
good, pricing firm, and competition rational. Commodity segments of electronic 
technology  such  as standard semiconductors, semiconductor capital equipment, 
and  hardware  systems  were  particularly  robust, as were communications and 
medical  technology.  A  number  of  science  and  technology  issues-from the 
competing  treatments  for  multiple  sclerosis to the flaw in Intel's Pentium 
processor-made  the  headlines,  increasing  investor  awareness of the entire 
sector.  Also,  industry  consolidation  and  the potential for merger-related 
windfalls   became   significant   influences,   as   cellular   giant   McCaw 
Communications,  software  vendors  Intuit  and  Powersoft,  and biotechnology 
leader Chiron became party to major transactions. All these factors created an 
environment  that could be described as the monetary sequel to "Revenge of the 
Nerds."                                                                        
    Although  investing  in  the  science  and  technology  sector  remains  a 
challenging   endeavor,  many  attributes  continue  to  make  it  attractive. 
Technology  is among the purest of growth sectors. As world economies navigate 
through  the  information  age, technology will become increasingly pervasive, 
and   U.S.  companies  dominate  key  technologies  such  as  microprocessors, 
communications, software, biotechnology, and environmental remediation. As the 
technological  evolution  expands from the office to the home and from data to 
communications  and  entertainment, the underlying growth dynamics for science 
and technology companies should be sustained.                                  
                                                                               
PORTFOLIO REVIEW                                                               
During 1994, your Fund's broad charter and our efforts to diversify the Fund's 
exposure across segments unrelated to the computer industry had mixed results. 
Our  holdings  of  wireless and biotechnology stocks generated strong returns, 
but investments in stocks of data services and media services companies were a 
drag  on  performance.  Once  again,  returns  were  highest within electronic 
technology, the Fund's largest investment segment.                             
    We  remain  comfortable  with  our  strategy of running a diversified, but 
concentrated,  portfolio. At year-end, your Fund held fewer than 50 individual 
stocks spread among six rapidly growing segments of the science and technology 
sector,  each representing between 10% and 20% of portfolio assets. The top 10 
positions composed approximately 43% of Fund assets.                           
    Strategically,  we  are pursuing opportunities along the following secular 
(long-term)   investment   themes:   client-server  computing,  remote/on-line 
communications,  digital  pervasiveness,  the widening appeal of wireless, and 
the scarcity value of biotechnology.                                           
                                                                               
                                                                               
<PAGE>                                                                       
                                                                               
                                                                               
    The  industry's  continuing  transition  to  open, networked client-server 
computing  platforms is the most significant trend in the commercial computing 
marketplace.   This   trend  is  driving  application  development  away  from 
centralized  mainframes  and proprietary minicomputer networks to distributed, 
desktop  workstations.  Beneficiaries  of  this shift include software vendors 
SYBASE,  ORACLE,  and  SAP  and  networking  equipment  manufacturers 3COM and 
CASCADE COMMUNICATIONS, all of which contributed materially to 1994 returns.   
    As the technological evolution expands from the office to include the home 
and  from  data  to  include  communications,  entertainment,  and  electronic 
commerce,  entirely new technologies will be needed to keep remote workers and 
consumers  informed  and  entertained  in  real  time. Companies positioned to 
benefit from this evolution include software vendors ADOBE SYSTEMS and INTUIT, 
electronic  transaction  processor  FIRST  FINANCIAL  MANAGEMENT,  and  remote 
communications equipment vendor SHIVA CORPORATION.                             
    Digital  pervasiveness  reflects  the  industry's  mandate  to make higher 
performance products both smaller and cheaper through the use of semiconductor 
technologies.  Within  this arena, programmable logic vendor XILINX and analog 
semiconductor  manufacturer MAXIM INTEGRATED PRODUCTS were strong contributors 
to 1994 Fund performance.                                                      
    Improving   worldwide  economies,  tiered  pricing  structures,  declining 
handset  prices,  expanding  distribution  channels, digital technologies, and 
intensified  marketing have converged to accelerate the growth of cellular and 
paging  services around the world. These dynamics, by making wireless services 
more  affordable  and  accessible, are increasing consumer demand for wireless 
communications.  We  are  concentrating  in  stocks  of  service and equipment 
providers with strong growth dynamics, proven business models, and established 
worldwide   franchises.   Cellular   operator   VODAFONE   and  infrastructure 
manufacturer NOKIA are two key investments in this area.                       
    The  consolidation  of  the pharmaceutical industry will create increasing 
demand  for  companies  with  biopharmaceutical  know-how  and  a  library  of 
promising  compounds. As the myriad of small biotechnology companies that came 
public  in the early 1990s burn their financial resources and face extinction, 
larger  companies  will  have  the  opportunity  to  cheaply acquire promising 
technologies.   Accordingly,   we   believe  there  is  scarcity  value  among 
established, technology-rich, well-capitalized biotech companies such as AMGEN 
and CHIRON.                                                                    
                                                                               
OUTLOOK                                                                        
We  are  taking  a  watchful  approach  to the first half of 1995. The Federal 
Reserve  appears intent on slowing the domestic economy by continuing to raise 
interest  rates,  and  turmoil persists in foreign markets. Additionally, with 
the  personal computer industry in transition during the first two quarters of 
the year, we expect the rate of growth in the electronic technology segment to 
moderate  temporarily.  While  a  broad  restructuring  is no longer an issue, 
health care companies will have to adjust to evolving market dynamics.         
    Business  within  the  science and technology sector is good almost across 
the  board,  but these stocks have had a nice run over the past six months and 
valuations  are  not  cheap.  Still,  we  continue  to  be  excited  about the 
longer-term  prospects  for science and technology stocks and remain committed 
to capitalizing on these opportunities for our shareholders.                   
                                                                               
                        Respectfully submitted,                                
                                                                               
                        [SIG]                                                  
                                                                               
                        Charles A. Morris                                      
                        President and Chairman of the                          
                        Investment Advisory Committee                          
                                                                               
January 19, 1995                                                               
                                                                               
                                                                               
<PAGE>                                                                       
                                                                               
                                                                               
Contributions to the Change in Net Asset Value Per Share                       
                                                                               
Three Months Ended December 31, 1994                                           
- ------------------------------------------------------
TEN BEST CONTRIBUTORS                                                          
Intuit                                      25 [cents]                         
Xilinx                                      23                                 
Autodesk                                    22                                 
Chiron                                      17                                 
Silicon Valley Group                        16                                 
Nokia                                       10                                 
DSC Communications                          10                                 
StrataCom**                                  9                                 
First Financial Management                   9                                 
Sun Microsystems                             8                                 
- ------------------------------------------------------                         
Total                                      149 [cents]                         
                                                                               
TEN WORST CONTRIBUTORS                                                         
Biogen                                     -13 [cents]                         
Adobe Systems*                               5                                 
Zilog**                                      5                                 
Centocor**                                   4                                 
SEI                                          4                                 
Advanced Micro Devices**                     3                                 
Mobile Telecommunication Technologies        3                                 
Synopsys                                     3                                 
First Data**                                 2                                 
QUALCOMM                                     2                                 
- ------------------------------------------------------                         
Total                                      -44 [cents]                         
- ------------------------------------------------------                         
  *Position added                                                              
 **Position eliminated                                                         
***Formerly Wellfleet Communications; position eliminated.                     
                                                                               
                                                                               
Twelve Months Ended December 31, 1994                                          
- ------------------------------------------------------ 
TEN BEST CONTRIBUTORS                                                          
Autodesk                                    50 [cents]                         
Xilinx                                      40                                 
Intuit                                      30                                 
Oracle Systems                              28                                 
Chiron*                                     27                                 
SAP*                                        23                                 
Sybase                                      21                                 
Glenayre Technologies                       21                                 
Silicon Valley Group*                       19                                 
Microchip Technology                        19                                 
- ------------------------------------------------------                         
Total                                      278 [cents]                         
                                                                               
TEN WORST CONTRIBUTORS 
Novell**                                   -20 [cents]                         
AST Research**                              17                                 
Bay Networks***                             16                                 
Advanced Micro Devices**                    13                                 
BroadBand Technologies**                    13                                 
Spectravision Class B**                     12                                 
Envirotest Systems**                        12                                 
Parametric Technology**                     10                                 
Texas Instruments**                         10                                 
SEI                                          8                                 
- ------------------------------------------------------                         
Total                                     -131 [cents]                         
- ------------------------------------------------------                         
                                                                               
Fiscal-Year Performance                                                        
Periods Ended December 31, 1994                                                
                                                                               
1 Year 5 Years*  Since Inception 9/30/87*                                      
- ------ --------- ------------------------                                      
15.79%  21.98%            18.71%                                               
- -----------------------------------------                                      
* Average Annual Compound Total Return                                         
                                                                               
Income  return  and  principal value represent past performance and will vary. 
Shares may be worth more or less at redemption than at original purchase.      
                                                                               
                                                                               
                                                                               
                                                                               
Twenty-Five Largest Holdings                                                   
December 31, 1994                                                              
                                                                               
                                Percent of                                     
Company                         Net Assets                                     
- ------------------------------- ----------                                     
Xilinx                             6.5%                                        
First Financial Management         5.7                                         
Nokia                              4.9                                         
Vodafone                           4.8                                         
Chiron                             4.4                                         
Autodesk                           4.3                                         
Amgen                              3.5                                         
Synopsys                           3.3                                         
Sybase                             2.8                                         
Biogen                             2.7                                         
AirTouch Communications            2.5                                         
Adobe Systems                      2.4                                         
Sun Microsystems                   2.4                                         
Silicon Graphics                   2.0                                         
Oracle Systems                     1.9                                         
Maxim Integrated Products          1.9                                         
Intuit                             1.8                                         
LM Ericsson                        1.8                                         
Silicon Valley Group               1.8                                         
DSC Communications                 1.6                                         
CUC International                  1.5                                         
SunGard Data Systems               1.4                                         
United International Holdings      1.3                                         
QUALCOMM                           1.3                                         
Motorola                           1.3                                         
- ------------------------------------------                                     
Total                             69.8%                                        
- ------------------------------------------                                     
                                                                               
Fiscal-Year Performance Comparison                                             
[chart]                                                                        
                                                                               
Fiscal-Year  Performance  Comparison: A two-line chart comparing the growth in 
an  initial  $10,000  investment  in  the Fund with the same investment in the 
Upper Science & Technology Index starting on 9/30/87 and ending on 12/31/94.   
                                                                               
                                                                               
<PAGE>                                                                       
                                                                               
                                                                               
Investment Record                                                              
T. Rowe Price Science & Technology Fund                                        
                                                                               
The  table below shows the investment record of one share of the T. Rowe Price 
Science  &  Technology Fund, purchased at the initial price of $10.00, for the 
period  9/30/87 through 12/31/94. Over this time, stock prices in general have 
risen.  The  results shown should not be considered as a representation of the 
income  or  capital gain or loss which may be realized from an investment made 
in the Fund today.                                                             
                                                                               
Per-Share Data                                                                 
                                                                               
<TABLE>                                                                                       
                      With Capital Gains and Income Dividends                    Annual     
                  Taken in Cash            Reinvested in Additional Shares    Total Return  
        --------------------------------- ----------------------------------  On Investment 
 Year              Capital                   Capital                            % Change    
 Ended  Asset       Gains        Income       Gains      Income    Value of  ---------------
 12/31  Value  Distributions/2/ Dividends Distributions Dividends Investment  Fund   S&P 500
- ------- ------ ---------------- --------- ------------- --------- ---------- ------- -------
<S>     <C>         <C>           <C>        <C>          <C>       <C>      <C>     <C>    
1987/1/ $8.02         -           $0.04         -         $0.04     $8.06    -19.4%  -22.5% 
 1988    8.57       $0.44         0.07        $0.44       0.07       9.13     13.3    16.5  
 1989   10.53        1.39         0.06        1.48        0.06      12.84     40.7    31.6  
 1990   10.05        0.24         0.09        0.29        0.11      12.67     -1.3    -3.1  
 1991   15.57        0.48           -         0.61          -       20.30     60.2    30.3  
 1992   17.33        1.12           -         1.46          -       24.10     18.8     7.6  
 1993   18.95        2.51           -         3.49          -       29.95     24.2    10.1  
 1994   21.64        0.30           -         0.47          -       34.68     15.8     1.3  
- --------------------------------------------------------------------------------------------
 Total              $6.48         $0.26       $8.24       $0.28                             
- --------------------------------------------------------------------------------------------
<FN>                                                                         
1. From inception 9/30/87 to 12/31/87                                          
2. Includes short-term capital gains of $0.38 in 1988, $1.23 in 1989, $0.06 in 
1990, $1.51 in 1993, and $0.10 in 1994.                                        
</TABLE>                                                                     
                                                                               
                                                                               
<PAGE>                                                                       
                                                                               
                                                                               
Statement of Net Assets (Value in thousands)                                   
T. Rowe Price Science & Technology Fund / December 31, 1994                    
                                                                               
Common Stocks --83.1%                                                          
ELECTRONIC TECHNOLOGY --48.8%                                                  
                                                       Value                 
                                                      --------                 
COMPUTER SOFTWARE --18.0%                                                      
   750,000shs. Adobe Systems.........................  $22,312                 
 1,000,000     Autodesk..............................   39,625                 
   150,000    *EPIC..................................    3,375                 
   250,000    *Intuit................................   16,688                 
   400,000    *Oracle Systems........................   17,650                 
    15,000     SAP (DEM).............................    8,499                 
   500,000    *Sybase................................   26,000                 
   700,000    *Synopsys..............................   30,625                 
                                                       164,774                 
                                                                               
SEMICONDUCTOR RELATED--13.6%                                                   
   170,000     Linear Technology.....................    8,415                 
   500,000    *Maxim Integrated Products.............   17,500                 
   400,000    *Microchip Technology..................   11,000                 
   200,000     Motorola..............................   11,575                 
   800,000    *Silicon Valley Group..................   16,500                 
 1,000,000    *Xilinx................................   59,250                 
                                                       124,240                 
                                                                               
NETWORKING &                                                                   
  TELECOMMUNICATIONS--10.3%                                                    
   200,000    *3Com..................................   10,312                 
   250,000    *Ascend Communications.................   10,188                 
   150,000    *Cascade Communications................    9,263                 
   400,000    *DSC Communications....................   14,350                 
   200,000    *Glenayre Technologies.................   11,550                 
   300,000     LM Ericsson (Class B) ADR.............   16,537                 
   500,000    *QUALCOMM..............................   12,000                 
   250,000    *Shiva.................................    9,969                 
                                                        94,169                 
                                                                               
COMPUTER HARDWARE SYSTEMS--5.8%                                                
   225,000     Apple Computer........................    8,775                 
   240,700*    Pinnacle Systems......................    3,611                 
   600,000    *Silicon Graphics......................   18,525                 
   625,000    *Sun Microsystems......................   22,187                 
                                                        53,098                 
                                                                               
PERIPHERALS--1.1%                                                              
   400,000    *Cognex................................   10,300                 
TOTAL ELECTRONIC TECHNOLOGY                            446,581                 
                                                                               
LIFE SCIENCES & HEALTH CARE--10.7%                                             
PHARMACEUTICALS--10.7%                                                         
   550,000shs.*Amgen.................................  $32,450                 
   600,000    *Biogen................................   25,050                 
   500,000    *Chiron................................   40,187                 
TOTAL LIFE SCIENCES & HEALTH CARE....................   97,687                 
                                                                               
DATA SERVICES--9.2%                                                            
COMPUTER SERVICES--7.7%                                                        
   850,000     First Financial Management............   52,381                 
   342,800     SEI...................................    5,913                 
   325,000    *SunGard Data Systems..................   12,513                 
                                                        70,807                 
                                                                               
CONSUMER INFORMATION SERVICES--1.5%                                            
   400,000    *CUC International.....................   13,400                 
TOTAL DATA SERVICES                                     84,207                 
                                                                               
MEDIA/TELECOMMUNICATION SERVICES--9.7%                                         
MEDIA--1.3%                                                                    
   700,000    *United International Holdings                 
               (Class A).............................   12,250
                                                                               
TELECOMMUNICATION SERVICES--8.4%                                               
   800,000    *AirTouch Communications...............   23,300                 
   500,000    *Mobile Telecommunication                                        
                 Technologies........................    9,750                 
 1,300,000     Vodafone ADR..........................   43,712                 
                                                        76,762                 
TOTAL MEDIA/TELECOMMUNICATION SERVICES...............   89,012                 
                                                                               
ENVIRONMENTAL SERVICES--0.3%                                                   
PROCESS SERVICES--0.3%                                                         
 1,000,000    *Canarc Resources (CAD)................    2,495                 
                                                                               
TOTAL ENVIRONMENTAL SERVICES                             2,495                 
                                                                               
TOTAL MISCELLANEOUS COMMON STOCKS-4.4%                  40,401                 
                                                                               
TOTAL COMMON STOCKS (COST $608,789)                    760,383                 
                                                                               

<PAGE>


PREFERRED STOCKS--5.2%                                                         
   600,000shs. Nokia ADR                               $45,000                 
TOTAL MISCELLANEOUS PREFERRED-0.3%                       2,376                 
TOTAL PREFERRED STOCKS (COST $41,550)                   47,376                 
                                                                               
Short-Term Investments--11.7%                                                  
COMMERCIAL PAPER--11.2%                                                        
$5,000,000     Abbey National North America,                                   
                 5.50%, 2/2/95.......................    4,930                 
 5,000,000     American Express Company                                        
                 4(2), 6.05%, 1/17/95................    4,972                 
 5,000,000     Asset Securitization                                            
                 Cooperative, 4(2),                                            
                 5.45%, 1/18/95......................    4,935                 
 5,000,000     B.A.T. Capital, 6.03%, 1/6/95.........    4,986                 
 5,000,000     Banc One, 4(2), 6.00%,                                          
                 1/11/95.............................    4,972                 
 5,000,000     Caisse des Depots et                                            
                 Consignations, 4(2),                                          
                 6.02%, 1/19/95......................    4,965                 
 5,000,000     Chubb Capital,                                                  
                 6.05%, 1/13/95......................    4,975                 
 5,000,000     Compagnie Bancaire,                                             
                 6.10%, 2/22/95......................    4,931                 
 5,000,000     Countrywide Funding,                                            
                 6.30%, 1/5/95.......................    4,993                 
 5,000,000     Dover, 4(2), 6.08%, 1/9/95............    4,979                 
 5,000,000     General Electric Capital,                                       
                 6.00%, 1/12/95......................    4,981                 
 5,000,000     Hanson Finance (U.K.),                                          
                 5.40%, 1/25/95......................    4,926                 
17,000,000     John Hancock Capital, 4(2),                                     
                 6.00%, 1/5/95.......................   16,983                 
 5,000,000     Preferred Receivables                                           
                 Funding, 6.00%, 2/2/95..............    4,947                 
 1,108,000     President & Fellows Harvard                                     
                 College, 6.00%, 1/3/95..............    1,107                 
 5,000,000     Reed Elsevier, 6.05%, 1/19/95.........    4,963                 
 5,000,000     Total Compagnie Francaise                                       
                 des Petroles, 6.00%, 1/9/95.........    4,973                 
$5,000,000     Toyota Motor Credit                                             
                 Company, 6.07%, 2/6/95                 $4,944                 
 5,000,000     US West Communications,                                         
                 4(2), 6.05%, 1/12/95................    4,976                 
                                                       102,438                 
                                                                               
CERTIFICATES OF DEPOSIT--0.5%                                                  
 5,000,000     Societe Generale,                                               
                 5.80%, 3/1/95.......................    5,001                 
TOTAL SHORT-TERM INVESTMENTS                                                   
  (COST $107,439)                                      107,439                 
- --------------------------------------------------------------                 
TOTAL INVESTMENTS IN SECURITIES--100.0%                                        
(COST $757,778)......................................  915,198                 
- --------------------------------------------------------------                 
Other Assets Less Liabilities                            (146)                 
                                                                               
NET ASSETS CONSISTING OF:                                                      
Accumulated realized gains/losses--                                            
  net of distributions                 $27,103                                 
Net unrealized gain................... 157,420                                 
Paid-in-capital applicable to                                                  
  42,290,439 shares of $0.01 par value                                         
  capital stock outstanding;                                                   
  1,000,000,000 shares authorized..... 730,529                                 
                                       --------                                
NET ASSETS .................................... $915,052                       
                                                --------                       
                                                --------                       
NET ASSETS VALUE PER SHARE..................... $21.64                         
                                                --------                       
                                                --------                       
- --------------------------------------------------------                       
       * Non-income producing
[dagger] Affiliated company  
    4(2) Commercial Paper sold within terms of a
         private placement memorandum, exempt from 
         registration under section 4.2 of the     
         Securities Act of 1933, as amended, and   
         may be sold only to dealers in that       
         program or other "accredited investors."  
     CAD Canadian dollar                           
     DEM German deutschemark    
                                                                               
The accompanying notes are an integral part of these financial statements.     
                                                                               
                                                                               
<PAGE>                                                                       
                                                                               
                                                                               
Statement of Operations                                                        
T. Rowe Price Science & Technology Fund / Year Ended December 31, 1994         
                                                                               
                                                    (Amounts in                
                                                     thousands)                
INVESTMENT INCOME                
Income                
Interest...........................................      $2,144                
  Dividends........................................       1,257                
                                                    -----------                
  Total income.....................................       3,401                
                                                    -----------                
Expenses                                                                       
  Investment management............................       4,467                
  Shareholder servicing............................       2,074                
  Registrations....................................         180                
  Custody and accounting...........................         155                
  Prospectus and shareholder reports...............         133                
  Proxy and annual meeting.........................          70                
  Legal and auditing ..............................          27                
  Directors........................................          19                
  Miscellaneous....................................          17                
                                                    -----------                
  Total expenses...................................       7,142                
                                                    -----------                
Net investment loss................................     (3,741)                
                                                    -----------                
                                                                               
REALIZED AND UNREALIZED GAIN (LOSS)                                            
Net realized gain (loss) on:                                                   
  Securities ......................................      29,821                
  Foreign currency transactions....................       (120)                
                                                    -----------                
  Net realized gain................................      29,701                
                                                    -----------                
Change in net unrealized gain or loss on:                                      
  Securities.......................................      84,768                
  Other   assets  and  liabilities  denominated  in                           
    foreign currencies.............................           1
                                                    -----------                
  Change in net unrealized gain or loss............      84,769                
                                                    -----------                
Net realized and unrealized gain...................     114,470                
                                                    -----------                
                                                                               
INCREASE IN NET ASSETS FROM OPERATIONS.............    $110,729                
                                                    -----------                
                                                    -----------                
- ---------------------------------------------------------------                
                                                                               
The accompanying notes are an integral part of these financial statements.     
                                                                               
                                                                               
<PAGE>                                                                       
                                                                               
                                                                               
Statement of Changes in Net Assets                                             
T. Rowe Price Science & Technology Fund                                        
                                                                               
                                           Year Ended December 31              
                                          -------------------------            
                                                  1994         1993            
                                          ------------ ------------            
                                           (Amounts in thousands)              
  Net investment loss....................     $(3,741)     $(2,541)            
  Net realized gain .....................       29,701       70,829            
  Change in net unrealized gain or loss..       84,769       12,088            
                                          ------------ ------------            
  Increase in net assets from operations.      110,729       80,376            
                                          ------------ ------------            
Distributions to shareholders                                                  
  Net realized gain......................     (12,349)     (57,955)            
                                          ------------ ------------            
  Decrease in net assets from                 (12,349)     (57,955)            
distributions............................                                      
                                          ------------ ------------            
Capital share transactions/1/                                                  
  Shares sold............................      582,569      377,713            
  Distributions reinvested...............       11,887       55,908            
  Shares redeemed........................    (279,238)    (235,633)            
                                          ------------ ------------            
  Increase in net assets from                                                  
  capital share transactions.............      315,218      197,988            
                                          ------------ ------------            
Increase in net assets...................      413,598      220,409            
                                                                               
NET ASSETS                                                                     
  Beginning of year......................      501,454      281,045            
  End of year............................     $915,052     $501,454            
                                          ------------ ------------            
                                          ------------ ------------            
- -------------------------------------------------------------------            
/1/Capital share transactions (number of shares)                               
  Shares sold............................       29,623       20,118            
  Distributions reinvested...............          552        3,035            
  Shares redeemed........................     (14,354)     (12,901)            
                                          ------------ ------------            
  Increase in capital share outstanding..       15,821       10,252            
                                          ------------ ------------            
                                          ------------ ------------            
- -------------------------------------------------------------------            
The accompanying notes are an integral part of these financial statements.     
                                                                               
Notes to Financial Statements                                                  
T. Rowe Price Science & Technology Fund / December 31, 1994                    
                                                                               
NOTE 1 - SIGNIFICANT ACCOUNTING POLICIES                                       
T.  Rowe  Price  Science  & Technology Fund (the Fund) is registered under the 
Investment   Company  Act  of  1940  as  a  diversified,  open-end  management 
investment company.                                                            
                                                                               
A)  Valuation  -  Equity securities listed or regularly traded on a securities 
exchange  (including  Nasdaq) are valued at the last quoted sales price on the 
day the valuations are made. A security which is listed or traded on more than 
one  exchange  is valued at the quotation on the exchange determined to be the 
primary  market  for  such  security. Other equity securities and those listed 
securities  that  are  not  traded  on  a particular day are valued at a price 
within  the  limits  of the latest bid and asked prices deemed by the Board of 
Directors, or by persons delegated by the Board, best to reflect fair value.   
                                                                               
                                                                               
<PAGE>                                                                       
                                                                               
                                                                               
    Short-term  debt  securities are valued at their cost which, when combined 
with accrued interest, approximates fair value.                                
    For purposes of determining the Fund's net asset value per share, the U.S. 
dollar  value  of  all  assets  and liabilities initially expressed in foreign 
currencies is determined by using the mean of the bid and offer prices of such 
currencies against U.S. dollars quoted by a major bank.                        
    Assets  and  liabilities  for  which  the  above  valuation procedures are 
inappropriate or are deemed not to reflect fair value are stated at fair value 
as determined in good faith by or under the supervision of the officers of the 
Fund, as authorized by the Board of Directors.                                 
B)  Affiliated  Companies  -  Investments  in  companies  5%  or more of whose 
outstanding  voting securities are held by the Fund are defined as "Affiliated 
Companies" in Section 2(a)(3) of the Investment Company Act of 1940.           
                                                                               
C)  Currency  translation  -  Assets  and  liabilities are converted into U.S. 
dollars  at  the  prevailing exchange rate at the end of the reporting period. 
Purchases  and sales of securities and income and expenses are translated into 
U.S.   dollars   at  the  prevailing  exchange  rate  on  the  dates  of  such 
transactions.  The effect of changes in foreign exchange rates on realized and 
unrealized  security gains or losses is reflected as a component of such gains 
or losses.                                                                     
                                                                               
D)  Other  - Income and expenses are recorded on the accrual basis. Investment 
transactions  are  accounted  for on the trade date. Realized gains and losses 
are reported on an identified cost basis. Dividend income and distributions to 
shareholders  are  recorded  by  the  Fund on the ex-dividend date. Income and 
capital  gain  distributions  are determined in accordance with federal income 
tax  regulations  and  may  differ  from  those  determined in accordance with 
generally accepted accounting principles.                                      
                                                                               
NOTE 2 - INVESTMENT TRANSACTIONS                                               
Purchases  and  sales  of portfolio securities, other than short-term and U.S. 
Government  securities,  aggregated $76,241,000 and $53,392,000, respectively, 
for the year ended December 31, 1994.                                          
                                                                               
NOTE 3 - FEDERAL INCOME TAXES                                                  
No  provision  for  federal income taxes is required since the Fund intends to 
continue  to  qualify  as a regulated investment company and distribute all of 
its taxable income.                                                            
    In order for the Fund's capital accounts and distributions to shareholders 
to   reflect   the  tax  character  of  certain  transactions,  $3,741,000  of 
undistributed net investment income and $297,000 of undistributed net realized 
gains were reclassified as a decrease to paid-in-                              
capital during the year ended December 31, 1994. The results of operations and 
net assets were not affected by the reclassifications.                         
    At December 31, 1994, the aggregate cost of investments for federal income 
tax  and financial reporting purposes was $757,778,000 and net unrealized gain 
aggregated   $157,420,000,   of  which  $167,894,000  related  to  appreciated 
investments and $10,474,000 to depreciated investments.                        
    For  Federal  income  tax  purposes  the  Fund paid distributions from net 
long-term  capital gains of $8,544,000. This amount may differ from that cited 
elsewhere  in  this report due to differences in the calculation for financial 
reporting and Federal income tax purposes.                                     
                                                                               
NOTE 4 - RELATED PARTY TRANSACTIONS                                            
The  investment  management  agreement  between  the  Fund  and  T. Rowe Price 
Associates,  Inc.  (the  Manager) provides for an annual investment management 
fee,  of  which $504,000 was payable at December 31, 1994. The fee is computed 
daily  and paid monthly, and consists of an Individual Fund Fee equal to 0.35% 
of  average  daily  net  assets and a Group Fee. The Group Fee is based on the 
combined assets of certain mutual funds sponsored by the Manager or Rowe-Price 
Fleming  International, Inc. (the Group). The Group Fee rate ranges from 0.48% 
for  the  first  $1  billion  of  assets  to 0.31% for assets in excess of $34 
billion.  At  December  31,  1994,  and for the year then ended, the effective 
annual  Group  Fee rate was 0.34%. The Fund pays a pro rata share of the Group 
Fee based on the ratio of its net assets to those of the Group.                
                                                                               
                                                                               
<PAGE>                                                                       
                                                                               
                                                                               
    In addition, the Fund has entered into agreements with the Manager and two 
wholly-owned  subsidiaries of the Manager, pursuant to which the Fund receives 
certain  other  services.  The  Manager  computes  the  daily  share price and 
maintains  the  financial  records  of  the Fund. T. Rowe Price Services, Inc. 
(TRPS)  is  the  Fund's  transfer  and  dividend disbursing agent and provides 
shareholder  and administrative services to the Fund. T. Rowe Price Retirement 
Plan  Services,  Inc.  provides  subaccounting  and recordkeeping services for 
certain  retirement  accounts invested in the Fund. The Fund incurred expenses 
pursuant  to  these related party agreements totaling approximately $1,760,000 
for  the  year  ended  December  31,  1994,  of  which $172,000 was payable at 
year-end.                                                                      
                                                                               
Financial Highlights                                                           
T. Rowe Price Science & Technology Fund                                        
                                                                               
<TABLE>                                                                                  
                                             For a share outstanding throughout each     
                                          ---------------------------------------------- 
                                                     Year Ended December 31,             
                                          ---------------------------------------------- 
                                              1994     1993      1992      1991     1990 
                                          ---------------------------------------------- 
<S>                                         <C>       <C>      <C>       <C>      <C>    
Net Asset Value,                                                                         
  BEGINNING OF YEAR .....................  $18.95  $17.33    $15.57    $10.05    $10.53
                                          -------- -------- --------- --------- -------- 
Investment Activities    
  Net investment income (loss)...........   (0.09)  (0.05)*   (0.10)*   (0.01)*    0.09* 
  Net realized and unrealized                                                            
    gain (loss)..........................     3.08     4.18      2.98      6.01   (0.24) 
                                          -------- -------- --------- --------- -------- 
Total from Investment Activities.........     2.99     4.13      2.88      6.00   (0.15) 
                                          -------- -------- --------- --------- -------- 
Distributions                                                                            
  Net investment income..................        -        -         -         -   (0.09) 
  Net realized gain......................   (0.30)   (2.51)    (1.12)    (0.48)   (0.24) 
                                          -------- -------- --------- --------- -------- 
Total Distributions......................   (0.30)   (2.51)    (1.12)    (0.48)   (0.33) 
                                          -------- -------- --------- --------- -------- 
Net Asset Value, End of YEAR.............   $21.64   $18.95    $17.33    $15.57   $10.05 
                                          -------- -------- --------- --------- -------- 
                                          -------- -------- --------- --------- -------- 
- ---------------------------------------------------------------------------------------- 
RATIOS/SUPPLEMENTAL DATA                                                       
Total Return.............................    15.8%    24.2%    18.8%*    60.2%*  (1.3)%* 
Ratio of Expenses to Average                                                             
  Net Assets.............................    1.11%    1.25%    1.25%*    1.25%*   1.25%* 
Ratio of Net Investment Income                                                           
  to Average Net Assets..................  (0.58)%  (0.68)%  (0.81)%*  (0.07)%*   0.91%* 
Portfolio Turnover Rate..................   113.3%   163.4%    144.3%    148.2%   182.5% 
Net Assets, End of Year                                                                  
  (in thousands)......................... $915,052 $501,454  $281,045  $166,048  $61,535 
- ---------------------------------------------------------------------------------------- 
*  Excludes  expenses  in  excess  of  a 1.25% voluntary expense limitation in 
effect through December 31, 1993.                                              
                                                                               
                                                                               
<PAGE>                                                                       
                                                                               
                                                                               
Report of Independent Accountants                                              
                                                                               
To the Shareholders and Board of Directors of                                  
T. Rowe Price Science & Technology Fund, Inc.                                  
                                                                               
    We  have audited the accompanying statement of net assets of T. Rowe Price 
Science  &  Technology  Fund,  Inc.,  as of December 31, 1994, and the related 
statement  of  operations for the year then ended, the statement of changes in 
net  assets  for  each  of  the  two  years  in the period then ended, and the 
financial  highlights  for  each  of  the five years in the period then ended. 
These  financial statements and financial highlights are the responsibility of 
the  Fund's  management.  Our responsibility is to express an opinion on these 
financial statements and financial highlights based on our audits.             
    We  conducted  our  audits  in accordance with generally accepted auditing 
standards.  Those  standards  require  that  we  plan and perform the audit to 
obtain  reasonable  assurance  about  whether  the  financial  statements  and 
financial  highlights  are  free  of  material misstatement. An audit includes 
examining, on a test basis, evidence supporting the amounts and disclosures in 
the  financial statements. Our procedures included confirmation of investments 
owned  as  of  December  31,  1994,  by  correspondence with the custodian and 
brokers.  An  audit also includes assessing the accounting principles used and 
significant  estimates  made  by management, as well as evaluating the overall 
financial  statement  presentation.  We  believe  that  our  audits  provide a 
reasonable basis for our opinion.                                              
    In  our  opinion,  the  financial  statements  and  financial  highlights, 
referred  to  above,  present  fairly, in all material respects, the financial 
position  of  T. Rowe Price Science & Technology Fund, Inc. as of December 31, 
1994,  the  results  of  its  operations,  the  changes  in its net assets and 
financial  highlights  for  each of the respective periods stated in the first 
paragraph in conformity with generally accepted accounting principles.         
                                                                               
                                                      COOPERS & LYBRAND L.L.P. 
                                                                               
Baltimore, Maryland                                                            
January 23 , 1995                                                              
                                                                               
                                                                               
<PAGE>                                                                       
                                                                               
                                                                               
Shareholder Services                                                           
                                                                               
To help shareholders monitor their current investments and make decisions that 
accu-rately reflect their financial goals, T. Rowe                             
Price offers a wide variety of information and services-at no extra cost.      
                                                                               
KNOWLEDGEABLE SERVICE                                                          
REPRESENTATIVES                                                                
BY  PHONE-Shareholder  service representatives are available from 8:00 a.m. to 
10:00  p.m.,  Monday  -  Friday, and weekends from 9:00 a.m. to 5:00 p.m., ET. 
Call  1-800-225-5132  to speak directly with a representative who will be able 
to assist you with your accounts.                                              
                                                                               
IN  PERSON-Visit  one  of  our  investor  center  locations  to  meet  with  a 
representative who will be able to assist you with your accounts. While there, 
you can drop off applications or obtain prospectuses and other literature.     
                                                                               
AUTOMATED 24-HOUR SERVICES                                                     
    Tele*Access[registered  trademark]  (1-800-638-2587)  provides information
such  as  account  balance,  date  and amount of your last transaction, latest
dividend payment, and fund prices and yields. Additionally, you have the abil-
ity  to  request  prospectuses,  statements,  account  and  tax forms; reorder
checks; and initiate purchase, redemption, and exchange orders for identically 
registered accounts.                                                           
    PC*Access  provides the same information as Tele*Access, but on a personal 
computer via dial-up modem.                                                    
                                                                               
ACCOUNT SERVICES                                                               
    Checking-Write  checks  for $500 or more on any money market and bond fund 
accounts (except the High Yield Fund and Emerging Markets Bond Fund).          
    Automatic  Investing-Build  your  account  over time by investing directly 
from your bank account or paycheck with Automatic Asset Builder. Additionally, 
Automatic  Exchange enables you to set up systematic investments from one fund 
account  into another, such as from a money fund into a stock fund. A low, $50 
minimum makes it easy to get started                                           
    Automatic Withdrawal-If you need money from your fund account on a regular 
basis, you can establish scheduled, automatic redemptions.                     
    Dividend  and  Capital  Gains Payment Options-Reinvest all or some of your 
distributions  or  take  them  in  cash.  We  give you maximum flexibility and 
convenience.                                                                   
                                                                               
INVESTMENT INFORMATION                                                         
    Combined   Statement-A  comprehensive  overview  of  your  T.  Rowe  Price 
accounts. The summary page gives your earnings by tax category, provides total 
portfolio  value,  and  lists  your investments by type-stock, bond, and money 
market. Detail pages itemize account transactions by fund.                     
    Quarterly Shareholder Reports-Portfolio managers review the performance of 
the funds in plain language and discuss T. Rowe Price's economic outlook.      
    The  T. Rowe Price Report-A quarterly newsletter with relevant articles on 
market  trends,  personal  financial  planning,  and  T. Rowe Price's economic 
perspective.                                                                   
    Insights-A library of information that includes reports on mutual fund tax 
issues, investment strategies, and financial markets.                          
    Detailed  Investment  Guides-Our  widely  acclaimed  Asset  Mix Worksheet, 
College  Planning Kit, Retirees Financial Guide, Retirement Planning Kit (also 
available on disk for PC use), and Guide to Risk-Adjusted Performance can help 
you determine and reach your investment goals.                                 
                                                                               
DISCOUNT BROKERAGE                                                             
You can trade stocks, bonds, options, precious metals, and other securities at 
a  substantial  savings  over  regular  commission  rates.  Call a shareholder 
service representative for more information.                                   
                                                                               
                                                                               
<PAGE>                                                                       
                                                                               
                                                                               
T. Rowe Price No-Load Mutual Funds                                             
                                                                               
STABILITY                                                                      
Prime Reserve                                                                  
Summit Cash Reserves                                                           
U.S. Treasury Money                                                            
California Tax-Free Money                                                      
New York Tax-Free Money                                                        
Summit Municipal Money Market                                                  
Tax-Exempt Money                                                               
                                                                               
CONSERVATIVE INCOME                                                            
Adjustable Rate U.S. Government                                                
Short-Term Bond                                                                
Short-Term Global Income                                                       
Summit Limited-Term Bond                                                       
U.S. Treasury Intermediate                                                     
Florida Insured Intermediate Tax-Free                                          
Maryland Short-Term Tax-Free Bond                                              
Summit Municipal Intermediate                                                  
Tax-Free Insured Intermediate Bond                                             
Tax-Free Short-Intermediate                                                    
Virginia Short-Term Tax-Free Bond                                              
                                                                               
INCOME                                                                         
Global Government Bond                                                         
GNMA                                                                           
New Income                                                                     
Spectrum Income                                                                
Summit GNMA                                                                    
U.S. Treasury Long-Term                                                        
California Tax-Free Bond                                                       
Georgia Tax-Free Bond                                                          
Maryland Tax-Free Bond                                                         
New Jersey Tax-Free Bond                                                       
New York Tax-Free Bond                                                         
Summit Municipal Income                                                        
Tax-Free Income                                                                
Virginia Tax-Free Bond                                                         
                                                                               
AGGRESSIVE INCOME                                                              
Emerging Markets Bond                                                          
High Yield                                                                     
International Bond                                                             
Tax-Free High Yield                                                            
                                                                               
CONSERVATIVE GROWTH                                                            
Balanced                                                                       
Capital Appreciation                                                           
Dividend Growth                                                                
Equity Income                                                                  
Equity Index                                                                   
Growth & Income                                                                
Spectrum Growth                                                                
Value                                                                          
                                                                               
GROWTH                                                                         
Blue Chip Growth                                                               
European Stock                                                                 
Growth Stock                                                                   
International Stock                                                            
Japan                                                                          
Mid-Cap Growth                                                                 
New Era                                                                        
Small-Cap Value                                                                
                                                                               
AGGRESSIVE GROWTH                                                              
Capital Opportunity                                                            
International Discovery                                                        
Latin America                                                                  
New America Growth                                                             
New Asia                                                                       
New Horizons                                                                   
OTC                                                                            
Science & Technology                                                           
                                                                               
PERSONAL STRATEGY FUNDS                                                        
Personal Strategy Income                                                       
Personal Strategy Balanced                                                     
Personal Strategy Growth                                                       
                                                                               
Call  if  you  want  to  know  about  any T. Rowe Price Fund. We'll send you a 
prospectus with more complete information, including management fees and other 
expenses. Read it carefully before you invest or send money.                   
                                                                               


</TABLE>


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