PRICE T ROWE SCIENCE & TECHNOLOGY FUND INC
N-30D, 1996-02-02
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                                  ANNUAL REPORT

                             ----------------------
  
                            Science & Technology Fund

                             ----------------------

                       FOR YIELD, PRICE, LAST TRANSACTION,
                         AND CURRENT BALANCE, 24 HOURS,
                              7 DAYS A WEEK, CALL:
                            1-800-638-2587 toll free
                             625-7676 Baltimore area

                             ----------------------


                        FOR ASSISTANCE WITH YOUR EXISTING
                              FUND ACCOUNT, CALL:
                           Shareholder Service Center
                            1-800-225-5132 toll free
                             625-6500 Baltimore area

                             ----------------------


                                  T. ROWE PRICE
                              100 East Pratt Street
                            Baltimore, Maryland 21202

                             ----------------------

     This report is authorized for distribution only to shareholders and to
     others who have received a copy of the prospectus of the T. Rowe Price
                           Science & Technology Fund.
<PAGE>

================================================================================

Fellow Shareholders
- ---------------------------------------
    
     The Science & Technology Fund had an outstanding  year in 1995,  generating
positive  returns  every  quarter  and  rising  55%  for  the  year.  While  our
competitors  on average  showed a loss in the fourth  quarter as the  technology
rally faded, your fund squeezed out a small gain. Over the last six months,  the
fund  outperformed  the  unmanaged   Standard  &  Poor's  500  Stock  Index  and
significantly  outpaced its peer group average;  for the year ended December 31,
the fund exceeded both benchmarks.

- --------------------------------------------------------------------------------
Performance Comparison
================================================================================

                                   Periods Ended 12/31/95
                                  6 Months       12 Months
                                 ------------------------
Science & Technology Fund            18.4%         55.5%

S&P 500                              14.5          37.6

Lipper Science & Technology
  Funds Index                         7.9          36.8
================================================================================

     The fund's assets grew  significantly  last year and we want to welcome our
new  shareholders.  To all our  shareholders,  we reiterate  our  commitment  to
building value over the long term, as evidenced by the fund's  cumulative return
of 325% over the last five years. For the fourth  consecutive  year, your fund's
performance  ranked among the top 25 equity  funds in the country,  according to
Lipper  Analytical  Services.  (Lipper  ranked the fund #22 out of 3,130  equity
funds based on its total return for the 12 months ended  12/31/95.) We will work
diligently to extend this record on your behalf.

CAPITAL GAIN DISTRIBUTION 
- ---------------------------------------
     Your Board of Directors declared a total capital gain distribution of $4.54
per  share  for 1995.  This  distribution,  which  was  payable  December  28 to
shareholders  of record on December 26,  reflected a short-term  capital gain of
$2.48 and a long-term capital gain of $2.06. Your check or statement  confirming
the distribution was mailed in early January,  and Form 1099-DIV,  with complete
tax information, was mailed toward the end of the month.
<PAGE>

MARKET ENVIRONMENT 
- ---------------------------------------
     The past year was exhilarating for investors. As 1995 dawned,  expectations
called for robust economic growth and rising inflationary pressures. The Federal
Reserve  responded  last February by raising the key federal funds target to 6%,
its seventh hike in 12 months.  However,  as the year progressed,  the prolonged
Fed tightening cooled the overheated  economy and inflation  remained  moderate,
causing  interest  rates to fall sharply.  These  factors,  combined with strong
gains in corporate earnings,  lifted stock prices to new highs, with the S&P 500
rising  nearly 38% for the year.  The broad  equity  market  suffered no serious
correction all year long. The bond market,  buoyed by falling interest rates and
two cuts in the federal  funds rate in the last six months,  had one of its best
years ever.  The  benchmark  30-year  Treasury  bond  generated a return of 34%,
rivaling the performance of many equity categories.

     Science and  technology  stocks led the market  rally for most of the year.
They benefited from strong demand, constraints on supply that supported industry
pricing  and  margins,   a  favorable   currency  situation  that  kept  foreign
competitors at a  disadvantage,  and strong money flows into  aggressive  growth
mutual funds.  In the first half of the year,  electronic  technology  companies
prospered   from   surging   demand  for   personal   computers   and   wireless
communications,  and in the second  half they rode the wave of  Internet  mania.
Life  sciences  companies  experienced  steady  unit  growth,   reduced  pricing
pressures,  an abundance of clinical  successes,  and the beneficial impact of a
weakening dollar.

     The technology juggernaut finally slowed in the fourth quarter as near-term
demand slackened across several key segments of the computer and  communications
industries.  A  growing  number of  electronic  technology  companies  warned of
disappointing  fourth  quarter  financial  results and more  subdued  growth and
profit  prospects  in the  first  half of  1996.  Consequently,  stocks  of most
computer and  communications-related  companies suffered,  and sector volatility
increased.

     Science and technology  stocks could remain  turbulent in coming months due
to several factors:  valuations  remain above historical norms, many broad-based
mutual  funds still have  significant  positions in these  stocks,  and investor
psychology  has become a bit fragile.  However,  these  stocks  remain among the
purest of all  growth  stocks,  and U.S.  companies  continue  to  dominate  key
technologies such as microprocessors,  communications,  software, biotechnology,
and  environmental  remediation.  In addition,  the inherent  volatility  of the
sector perpetually provides cycles of attractive buying  opportunities  followed
by periods of surging returns.  Consequently, as the world navigates through the
information  age and  mankind  continues  its quest to extend  human  life,  the
long-term prospects for these stocks remain bright.
<PAGE>

PORTFOLIO REVIEW 
- ---------------------------------------
     During 1995, your fund's broad charter and our efforts to diversify  across
the sector helped keep us ahead of our peers. Our strategy remained focused on a
wide selection of science and technology  stocks.  On December 31, the portfolio
held less than 60 companies  spread among several  rapidly  growing  industries.
Collectively, electronic technology was our largest exposure, accounting for 70%
of fund assets (represented in the chart by blue-shaded  sections).  Media, data
services,  and life  sciences/health  care accounted for most of the balance. As
the year ended,  our top 10 positions (shown in the table following this letter)
composed approximately 38% of fund assets.

[Sector Diversification - a pie chart showing assets as of 12/31/95: 
Business Software 22%, Semiconductor-Related 21%, Networking 13%, Consumer 
Software 9%, Reserves and Other 9%, Data Services 9%, Media 8%,
Hardware/Peripherals 5%, Life Sciences/Health Care 4%.]

     We are pursuing investment  opportunities by tracking the following trends:
the  increasing  use of the  personal  computer as a  communications  tool,  the
continuing  shift away from  mainframes  toward  client-server  computing in the
workplace,  the popularity of  remote/on-line  communications,  growing consumer
demand  for  wireless  communications,  and the  increasing  scarcity  value  of
biotechnology.

     The  personal  computer  is  evolving  from  a  computational  device  to a
multimedia  communications tool. Instead of speedier number crunching,  computer
users now want to get connected -- to databases,  information  sources, and each
other.  This  evolution  should  continue to benefit  networking  vendor  ASCEND
COMMUNICATIONS,  semiconductor vendors XILINX and MAXIM INTEGRATED PRODUCTS, and
computer service provider AMERICA ONLINE, four of the fund's top contributors in
1995.

     The  industry's  transition  to  open,  networked  client-server  computing
platforms is the most significant trend in the commercial computing marketplace.
This trend is driving application  development away from centralized  mainframes
and  proprietary   minicomputers   toward  networks  of  desktop   workstations.
Beneficiaries  include software vendors BMC SOFTWARE and SYBASE,  and networking
equipment  manufacturers 3COM and BAY NETWORKS,  all of which remain significant
holdings.

     As the  technological  evolution expands from the office to the home -- and
from mundane data  services to  communications,  entertainment,  and  electronic
commerce -- entirely new technologies will be required to keep far-flung workers
and consumers  informed and  entertained in real time.  Companies  positioned to
benefit from this evolution  include  software vendors ADOBE SYSTEMS and INTUIT,
electronic   transaction  processor  FIRST  DATA,  and  remote  communications
equipment  vendor  SHIVA -- all of which were  significant  contributors  during
1995.

     Cellular  telephone  and paging  services  are growing  rapidly  around the
world,  driven  by  improving  global  economies,   tiered  pricing  structures,
declining handset prices, expanding distribution channels, digital technologies,
and intensified marketing. Wireless communications, like personal computers, are
increasingly  penetrating the consumer market. We are concentrating on stocks of
service and equipment providers with a strong presence overseas and exciting new
technologies.  Foreign  cellular  operator  VODAFONE  and  wireless  messaging
provider MOBILE TELECOMMUNICATION  TECHNOLOGIES are two key investments in this
area, even though the latter had a disappointing year.
<PAGE>

     As the pharmaceutical  industry consolidates,  the need for broad technical
expertise   and  a   deep   product   pipeline   will   favor   companies   with
biopharmaceutical know-how and a stable of promising drugs. Furthermore, as many
of the small biotechnology companies that went public in the early 1990s deplete
their financial resources and face extinction,  their larger competitors will be
able to acquire some promising  technologies  at bargain prices.  Therefore,  we
believe  there is  scarcity  value  among  established,  technology-rich,  well-
capitalized biotechnology companies, including AMGEN, ALZA, AND CEPHALON.

OUTLOOK
- ---------------------------------------
     We are taking a guarded  approach  toward the early part of 1996. The stock
market is at record levels, but earnings growth is moderating and interest rates
could rise in the months  ahead.  Growth in the  personal  computer and wireless
communications industries appears to be slowing from the torrid pace of the past
few years, and both electronic  technology and life sciences companies will have
to  perform  admirably  to  exceed  last  year's  results.  Moreover,   earnings
disappointments and price declines within the sector have become more prevalent.
Some stocks have fallen substantially from last year's highs.

     However,  we remain bullish on the science and  technology  sector over the
next 12 to 18 months.  During this period, the personal computer industry should
experience  accelerated  growth,  with  Intel  and  Microsoft  in the  midst  of
significant  product  rollouts.  In  addition,   the  nagging  uncertainty  over
potential  telecommunications  reform  will  likely  disappear,  while  exciting
digital  wireless  technologies  should hit the market.  Finally,  the  consumer
electronics  industry could experience  renewed growth as next- generation video
game and display platforms become available in meaningful  volumes. We are quite
encouraged by the sector's longer-term prospects and remain committed to seizing
these  wealth-building  opportunities on behalf of our shareholders.  Given this
sector's volatility, we remind all shareholders that the fund is not appropriate
for short-term goals.

                                         Respectfully submitted,

                                         [signature]
     
                                         Charles A. Morris
                                         President and Chairman of the
                                         Investment Advisory Committee

January 17, 1996
================================================================================
<PAGE>

                   A Word on Market Corrections
- --------------------------------------------------------------------------------

               After the stock market's spectacular run
          in 1995,  concerns about a "correction"  have
          intensified. Most market observers consider a
          correction to be a short and sometimes  steep
          decline  following a period of rising prices.
          Moderate  corrections of around 10% have been
          quite common, occurring on average about once
          every two years  over the last  half-century,
          according to Ned Davis Research.

               The market as  measured by the Dow Jones
          Industrial  Average  has  not  experienced  a
          moderate   correction   since   early   1994.
          Furthermore,  the Dow last hit a bear  market
          bottom --  defined  as a drop of at least 20%
          -- in October 1990.  Therefore,  it would not
          be surpr  ising to see a modest  pullback  in
          1996,  on the order of 5% to 10%. In fact, as
          we write,  the  market  has  gotten  off to a
          rocky start. 

               Corrections  are not only common,but can
          be  beneficial   for   long-term   investors,
          especially   those  who   invest  in  regular
          amounts through dollar cost  averaging.  In a
          correction,  overall  stock  prices  decline,
          often leading to more  attractive  valuations
          and good  buying  opportunities.  History has
          shown  that  investors  who  continue  to buy
          through a downturn  fare quite well. In fact,
          the Dow has proven resilient in the aftermath
          of past  corrections of around 10%, taking an
          average  of just six  months to  recover  its
          losses,  according to Ned Davis.  (To realize
          the  benefits of dollar cost  averaging,  you
          should be prepared to  continuously  purchase
          securities  over a period of time,  in up and
          down markets. This approach does not assure a
          gain nor protect you from a loss in declining
          markets.)

               We   raise   the   issue   of  a  market
          correction  not  as a  prediction,  but  as a
          reminder  that  stock  prices  do not move in
          only one direction. If you are satisfied that
          your  investments  are  appropriate  for your
          various  objectives,  we  recommend  that you
          stay the course when a correction  eventually
          occurs.
<PAGE>

================================================================================
                          Twenty-Five Largest Holdings
- --------------------------------------------------------------------------------
December 31, 1995
                                               Percent of
Company                                        Net Assets
- ----------------------------------------      ------------
BMC Software                                     5.6%
Maxim Integrated Products                        4.8
Vodafone                                         4.6
Xilinx                                           4.3
Adobe Systems                                    4.1
Intuit                                           3.4
Altera                                           3.0
First Data                                       2.9
Ascend Communications                            2.7
Broderbund Software                              2.7
Cirrus Logic                                     2.6
3Com                                             2.3
Cadence Design Systems                           2.2
Synopsys                                         2.1
Electronic Arts                                  2.0
Bay Networks                                     1.9
Mobile Telecom. Technologies                     1.9
CUC International                                1.9
Hewlett-Packard                                  1.8
America Online                                   1.6
ALZA                                             1.6
Informix                                         1.6
SunGard Data Systems                             1.5
Nokia                                            1.5
Silicon Graphics                                 1.5
                                             -----------
Total                                           66.1%

================================================================================
<PAGE>

Contributions to the Change in Net Asset Value Per Share
T. Rowe Price Science & Technology Fund
- --------------------------------------------------------------------------------
Six Months Ended December 31, 1995

TEN BEST CONTRIBUTORS

Ascend Communications                             86   cents
Intuit                                            71
America Online                                    42
Maxim Integrated Products                         39
Cascade Communications                            29
Cephalon                                          29
Macromedia*                                       25
Bay Networks                                      24
Cadence Design Systems                            23
Conner Peripherals                                23
                                                -------
Total                                            391   cents

TEN WORST CONTRIBUTORS

Hedging Position**                               -43   cents
Electronic Arts                                   21
Mobile Telecom. Technologies                      21
Silicon Graphics                                  18
Silicon Valley Group                              11
KLA Instruments                                   11
Symantec**                                         8  
Motorola**                                         7
SoftKey International**                            7
Vodafone                                           7
                                               --------
Total                                           -154   cents

================================================================================
<PAGE>

Twelve Months Ended December 31, 1995

TEN BEST CONTRIBUTORS

Ascend Communications                            121   cents
Intuit                                            84
Xilinx                                            73
Adobe Systems                                     72
America Online*                                   70
Cirrus Logic*                                     63
First Data                                        59
Maxim Integrated Products                         58
Nokia                                             49
Cephalon                                          47
                                               -------
Total                                            696   cents

TEN WORST CONTRIBUTORS

Hedging Position**                               -96   cents
Sybase                                            54
Electronic Arts                                   21
Silicon Graphics                                  13
AirTouch Communications**                         10
KLA Instruments                                   10
DSC Communications**                               9
Mobile Telecom. Technologies                       8
SoftKey International**                            7
Motorola**                                         7  
                                               --------
Total                                           -235   cents
- --------------------------------------------------------------------------------
*Position added
**Position eliminated
================================================================================
[Performance comparison line graph for Science and Technology Fund annual report
 December 31, 1995)]
================================================================================
                      Average Annual Compound Total Return
                        Periods Ended December 31, 1995
- --------------------------------------------------------------------------------
                                  Since
                                Inception
  1 Year         5 Years         9/30/87
 -------         -------      ------------
  55.53%          33.60%          22.66%

Investment return and principal value represent past performance and will vary.
Shares may be worth more or less at redemption than at original purchase.
================================================================================
<PAGE>
                               Investment Record
                    T. Rowe Price Science & Technology Fund
- --------------------------------------------------------------------------------
The table below shows the investment record of one share of the T. Rowe Price
Science & Technology Fund, purchased at the initial price of $10.00, for the
period 9/30/87 through 12/31/95. Over this time, stock prices in general have
risen. The results shown should not be considered as a representation of the
income or capital gain or loss which may be realized from an investment made in
the fund today.
<TABLE>
Per Share Data
- --------------------------------------------------------------------------------
  <S>        <C>          <C>               <C>         <C>               <C>        <C>            <C>         <C>
                                                 With Capital Gains and Income Dividends               Annual
                                   Taken in Cash Reinvested in Additional Shares                     Total Return
  Year       Net         Capital                       Capital                                       on Investment
  Ended     Asset        Gain            Income         Gain           Income       Value of           % Change
  12/31     Value     Distributions(1)   Dividends   Distributions     Dividends    Investment     Fund       S&P 500
 -------   --------  ----------------- ------------ ---------------   ----------    ----------    ------     ---------
  1987(2)  $ 8.02         --              $0.04           --             $0.04       $ 8.06       -19.4%      -22.5%
  1988       8.57      $ 0.44              0.07         $0.44             0.07         9.13         13.3        16.5
  1989      10.53        1.39              0.06          1.48             0.06        12.84         40.7        31.6
  1990      10.05        0.24              0.09          0.29             0.11        12.67         -1.3        -3.1
  1991      15.57        0.48             --             0.61               --        20.30         60.2        30.3
  1992      17.33        1.12             --             1.46               --        24.10         18.8         7.6
  1993      18.95        2.51             --             3.49               --        29.95         24.2        10.1
  1994      21.64        0.30             --             0.47               --        34.68         15.8         1.3
  1995      29.12        4.54             --             7.28               --        53.93         55.5        37.6

Total                  $11.02             $0.26       $ 15.52            $ 0.28
- --------------------------------------------------------------------------------
<FN>
(1)Includes short-term capital gains of $0.38 in 1988, $1.23 in 1989, $0.06 in
   1990, $1.51 in 1993, $0.10 in 1994; and $2.48 in 1995.
(2)From inception 9/30/87 to 12/31/87.
</FN>
</TABLE>
================================================================================
<PAGE>

Portfolio of Investments

T. Rowe Price Science & Technology Fund / December 31, 1995

(VALUES IN THOUSANDS)
- --------------------------------------------------------------------------------
                                                   Value   
                                                  -------- 
Common Stocks & Warrants-- 91.5% 

ELECTRONIC TECHNOLOGY -- 66.2% 
BUSINESS SOFTWARE -- 21.1%

  1,500,000 shs   Adobe Systems................  $  93,187
    270,000     * Baan Company.................     12,218
  3,000,000     * BMC Software.................    127,875
  1,200,000     * Cadence Design Systems.......     50,400
  1,200,000     * Informix.....................     36,075
    400,000     * Oracle Systems...............     16,950
    400,000     * PeopleSoft...................     17,050
  1,500,000     * PLATINUM technology..........     27,656
    950,800     * Sybase.......................     34,110
  1,250,000     * Synopsys.....................     47,656
    545,900     * Tivoli Systems...............     18,322
                                                                        481,499

CONSUMER SOFTWARE -- 9.0%
  1,000,000     * Broderbund Software..........     60,875
  1,750,000     * Electronic Arts..............     45,828
    992,300     * Intuit.......................     77,523
    400,000     * Macromedia...................     20,825
                                                                        205,051

SEMICONDUCTOR -- 15.6%
    750,000     * Actel........................      8,109
  1,400,000     * Altera.......................     69,562
  3,000,000     * Cirrus Logic.................     59,438
  2,850,000     * Maxim Integrated Products....    109,725
    300,000     * Microchip Technology.........     10,988
  3,250,000     * Xilinx.......................     98,719
                                                                        356,541

SEMICONDUCTOR EQUIPMENT -- 2.3%
    750,000     * KLA Instruments..............     19,594
  1,350,000     * Silicon Valley Group.........     34,172
                                                                         53,766
<PAGE>

NETWORKING -- 13.2%
  1,125,000     * 3Com.........................     52,523
    375,000     * ALANTEC......................     21,844
    750,000     * Ascend Communications........     60,891
  1,050,000     * Bay Networks.................     43,116
    400,000     * Cascade Communications.......     34,050
    425,000     * Cisco Systems................     31,742
    900,000       Nokia ADR....................     34,987
    325,000     * Shiva........................     23,725
                                                                        302,878

HARDWARE/PERIPHERALS -- 5.0%
  1,000,000     * Conner Peripherals...........     21,000
    500,000       Hewlett-Packard..............     41,875
    191,500     * Komag........................      8,785
    300,000     * Pinnacle.....................      7,538
  1,250,000     * Silicon Graphics.............     34,375
                                                                        113,573

TOTAL ELECTRONIC TECHNOLOGY   1,513,308

LIFE SCIENCES AND HEALTH CARE -- 3.7%
PHARMACEUTICALS -- 3.7%

  1,500,000     * ALZA (Class A)...............     37,125
    400,000     * Amgen........................     23,725
    600,000     * Cephalon.....................     24,488

TOTAL LIFE SCIENCES AND HEALTH CARE        85,338

INFORMATION SERVICES -- 9.3%

DATA SERVICES -- 9.3%
  1,000,000      * America Online..............     37,313
    144,000 wts  *#Bachman Information 
                     Systems, $3.28, 11/22/97..        724
  1,250,000 shs  * CUC International...........     42,656
  1,000,000        First Data..................     66,875
  1,000,000      * ITG.........................      9,500
  1,250,000      * SunGard Data Systems........     35,156
  1,318,000      * Tech Data...................     19,852

TOTAL INFORMATION SERVICES      212,076

MEDIA/TELECOMMUNICATIONS SERVICES -- 7.7%
TELECOMMUNICATIONS SERVICES -- 7.7%

  2,000,000      * Mobile Telecommunication 
                     Technologies..............     42,750
  1,250,000      * PanAmSat....................     27,656
  3,000,000        Vodafone ADR................    105,750

TOTAL MEDIA/TELECOMMUNICATIONS SERVICES   176,156
<PAGE>

ENVIRONMENTAL SERVICES -- 0.1%

PROCESS SERVICES -- 0.1%

  1,000,000      * Canarc Resources (CAD)......     1,025

TOTAL ENVIRONMENTAL SERVICES      1,025
 
- --------------------------------------------------------------------------------
MISCELLANEOUS COMMON STOCKS -- 4.5%                                     102,434

- --------------------------------------------------------------------------------
TOTAL COMMON STOCKS & WARRANTS
    (COST $1,642,477)         2,090,337
- --------------------------------------------------------------------------------

Preferred Stocks -- 0.2%
        720  shs *# Bachman Information
       Systems, Series A.............      5,508

- --------------------------------------------------------------------------------
TOTAL PREFERRED STOCKS (COST $2,362)                                      5,508
- --------------------------------------------------------------------------------

Short-Term Investments -- 6.7%

  $25,000,000    Federal Home Loan Bank
                   Discount Notes,
                   5.45%, 1/22/96..............     24,879
                 Federal Home Loan Mortgage
                   Discount Notes,
   40,000,000    5.47%, 1/22 - 1/25/96.........     39,801
   14,827,000    5.50%, 1/2/96.................     14,818
                 United States Treasury Bills,
   25,000,000    5.325%, 2/1/96................     24,663
   25,000,000    5.34%, 2/22/96................     24,666
   25,000,000    5.035%, 6/27/96...............     24,364


TOTAL SHORT-TERM INVESTMENTS (COST $153,191)        153,191

================================================================================
TOTAL INVESTMENTS IN SECURITIES -- 98.4% OF
    NET ASSETS (COST $1,798,030)                                      2,249,036
================================================================================

OTHER ASSETS LESS LIABILITIES..................      36,227

NET ASSETS.....................................  $2,285,263
                                                ============
  * Non-income producing
    Affiliated company
  # Securities contain some restrictions as to public
       resale -- total of such securities at year-end
       amounts to 0.27% of net assets.
CAD Canadian dollar


- --------------------------------------------------------------------------------
The accompanying notes are an integral part of these financial statements.
================================================================================
<PAGE>

Statement of Assets and Liabilities

T. Rowe Price Science & Technology Fund / Year Ended December 31, 1995
(IN THOUSANDS)

ASSETS
Investments in securities, at value
  Affiliated companies (cost $125,351).........................    $    137,375
  Other companies (cost $1,672,679)............................       2,111,661
                                                                    -----------
  Total investments in securities..............................       2,249,036
Other assets...................................................          77,511
                                                                    -----------
Total assets...................................................       2,326,547
                                                                    -----------
LIABILITIES....................................................          41,284
                                                                    -----------
NET ASSETS.....................................................    $  2,285,263
                                                                    ===========

NET ASSETS CONSIST OF:
Accumulated net realized gain/loss - net of distributions......    $    105,773
Net unrealized gain (loss).....................................         451,006
Paid-in-capital applicable to 78,484,473 
  shares of $0.01 par value capital stock
  outstanding; 1,000,000,000 shares authorized.................       1,728,484
                                                                    -----------
NET ASSETS.....................................................    $  2,285,263
                                                                    ===========
NET ASSET VALUE PER SHARE......................................    $      29.12
                                                                    ===========

- --------------------------------------------------------------------------------
The accompanying notes are an integral part of these financial statements.
================================================================================
<PAGE>
Statement of Operations

T. Rowe Price Science & Technology Fund / Year Ended December 31, 1995
(IN THOUSANDS)

INVESTMENT INCOME

Income
  Interest.....................................................    $     10,171
  Dividend (net of foreign taxes of $423)......................           4,122
                                                                    -----------
  Total income.................................................          14,293
                                                                    -----------
Expenses
  Investment management........................................          11,393
  Shareholder servicing........................................           4,466
  Registration.................................................             368
  Prospectus and shareholder reports...........................             303
  Custody and accounting.......................................             192
  Directors....................................................              32
  Legal and audit..............................................              23
  Miscellaneous................................................              47
                                                                    -----------
  Total expenses...............................................          16,824
                                                                    -----------
Net investment income..........................................          (2,531)
                                                                    -----------
REALIZED AND UNREALIZED GAIN (LOSS) 

Net realized gain (loss) on:
  Securities...................................................         446,056
  Options......................................................         (56,501)
  Foreign currency transactions................................              89
                                                                    -----------
  Net realized gain (loss).....................................         389,644
                                                                    -----------
Change in net unrealized gain or loss on:
  Securities...................................................         293,586
                                                                    -----------
Net realized and unrealized gain (loss)........................         683,230
                                                                    -----------
INCREASE (DECREASE) IN NET ASSETS FROM OPERATIONS..............     $   680,699
                                                                    ===========

- --------------------------------------------------------------------------------
The accompanying notes are an integral part of these financial statements.
================================================================================
<PAGE>

Statement of Changes in Net Assets

T. Rowe Price Science & Technology Fund
(IN THOUSANDS)
                                                         Year Ended December 31,
                                                           1995         1994
                                                        -----------  -----------
INCREASE (DECREASE) IN NET ASSETS FROM
Operations
  Net investment income ..........................     $   (2,531)   $  (3,741)
  Net realized gain (loss)........................        389,644       29,701
  Change in net unrealized gain or loss...........        293,586       84,769
                                                       -----------  -----------
  Increase (decrease) in net assets from 
     operations...................................        680,699      110,729
                                                       -----------  -----------
Distributions to shareholders
  Net realized gain...............................       (308,443)     (12,349)
                                                       -----------  -----------
Capital share transactions*
  Shares sold.....................................      1,486,892      582,569
  Distributions reinvested........................        300,634       11,887
  Shares redeemed.................................       (789,571)    (279,238)
                                                       -----------  -----------
  Increase (decrease) in net assets from capital 
     share transactions...........................        997,955       315,218
                                                       -----------  -----------
Increase (decrease) in net assets.................      1,370,211       413,598

NET ASSETS
Beginning of period...............................        915,052       501,454
                                                       -----------  -----------
End of period.....................................     $2,285,263    $  915,052
                                                       ===========  ===========

*Share information
  Shares sold.....................................         53,440        29,623
  Distributions reinvested........................         10,317           552
  Shares redeemed.................................        (27,563)      (14,354)
                                                       -----------  -----------
  Increase (decrease) in shares outstanding.......         36,194        15,821
                                                       ===========  ===========
     
- --------------------------------------------------------------------------------
The accompanying notes are an integral part of these financial statements.
================================================================================
<PAGE>

     Notes To Financial Statements
- --------------------------------------------------------------------------------
T. Rowe Price Science & Technology Fund / December 31, 1995


NOTE 1 - SIGNIFICANT ACCOUNTING POLICIES
- -------------------------------------------------

     T. Rowe Price Science & Technology Fund (the fund) is registered  under the
Investment Company Act of 1940 as a diversified,  open-end management investment
company.  

     A) Valuation - Equity securities listed or regularly traded on a securities
exchange  are valued at the last quoted  sales price at the time the  valuations
are made.  A  security  which is listed or traded on more than one  exchange  is
valued at the quotation on the exchange  determined to be the primary market for
such  security.  Listed  securities  that are not traded on a particular day and
securities that are regularly traded in the  over-the-counter  market are valued
at the mean of the latest bid and asked  prices.  Other  equity  securities  are
valued at a price within the limits of the latest bid and asked prices deemed by
the Board of Directors,  or by persons  delegated by the Board,  best to reflect
fair value.

     Short term debt  securities  are valued at their cost which,  when combined
with accrued interest, approximates fair value.

     For purposes of determining the fund's net asset value per share,  the U.S.
dollar  value of all  assets  and  liabilities  initially  expressed  in foreign
currencies  is  determined by using the mean of the bid and offer prices of such
currencies against U.S. dollars quoted by a major bank.

     Assets  and  liabilities  for  which  the above  valuation  procedures  are
inappropriate  or are deemed not to reflect  fair value are stated at fair value
as determined in good faith by or under the  supervision  of the officers of the
fund, as authorized by the Board of Directors.

     B)  Affiliated  Companies -  Investments  in  companies 5% or more of whose
outstanding  voting  securities  are held by the fund are defined as "Affiliated
Companies" in Section 2(a)(3) of the Investment Company Act of 1940.

     C) Currency  Translation - Assets and  liabilities are translated into U.S.
dollars at the  prevailing  exchange  rate at the end of the  reporting  period.
Purchases and sales of securities  and income and expenses are  translated  into
U.S. dollars at the prevailing  exchange rate on the dates of such transactions.
The effect of  changes in foreign  exchange  rates on  realized  and  unrealized
security  gains and losses is reflected as a component of such gains and losses.
<PAGE>

     D)  Other  -  Income  and  expenses  are  recorded  on the  accrual  basis.
Investment  transactions are accounted for on the trade date. Realized gains and
losses  are  reported  on  the  identified  cost  basis.   Dividend  income  and
distributions to shareholders are recorded by the fund on the ex-dividend  date.
Income and capital gain  distributions are determined in accordance with federal
income tax regulations  and may differ from those  determined in accordance with
generally accepted accounting principles.

NOTE 2 - INVESTMENT TRANSACTIONS
- -------------------------------------------------

     Consistent with its investment objective, the fund engages in the following
practices  to manage  exposure  to certain  risks and enhance  performance.  The
investment  objective,  policies,  program,  and  risk  factors  of the fund are
described  more fully in the  fund's  prospectus  and  Statement  of  Additional
Information. 

     A) Options - Call and put options on  securities  give the holder the right
to purchase  or sell,  respectively,  a security  at a  specified  price until a
certain  date.  Stock  index  call or put  options  give the holder the right to
receive cash,  based on market  movement,  equal to the  difference  between the
exercise  settlement  value of the index and the  exercise  price of the option.
Risks arise from possible  illiquidity  of the options market and from movements
in  security  values.  Transactions  in options  written  and  related  premiums
received during the year ended December 31, 1995, were as follows:


- --------------------------------------------------------------------------------

                                  Number of
                              Option Contracts       Premiums
                             -----------------      ----------
Options Outstanding at
  Beginning of Period                  --                --
Options Written                     8,000         $  2,543,000
Options Exercised                      --                --
Options Expired                    (5,000)            (935,000)
Options Closed                     (3,000)          (1,608,000)
                                -----------      ---------------
Options Outstanding at
  End of Period                        --         $      --
                             -----------------      ----------
================================================================================


     B)  Other -  Purchases  and  sales  of  portfolio  securities,  other  than
short-term   securities,    aggregated    $2,485,315,000   and   $1,936,654,000,
respectively, for the year ended December 31, 1995.
<PAGE>

NOTE 3 - FEDERAL INCOME TAXES 
- -------------------------------------------------

     No provision for federal income taxes is required since the fund intends to
continue to qualify as a regulated  investment company and distribute all of its
taxable income.

     In order for the fund's capital accounts and  distributions to shareholders
to  reflect  the  tax   character  of  certain   transactions,   $2,531,000   of
undistributed   net  investment   income  was  reclassified  as  a  decrease  to
undistributed  net realized  gains during the year ended  December 31, 1995. The
results of operations and net assets were not affected by the reclassifications.

     At December 31, 1995, the aggregate cost of investments  for federal income
tax and financial  reporting purposes was $1,798,030,000 and net unrealized gain
aggregated   $451,006,000,   of  which   $518,683,000   related  to  appreciated
investments and $67,677,000 to depreciated investments.

NOTE 4 - RELATED PARTY TRANSACTIONS
- -------------------------------------------------

     The  investment  management  agreement  between  the fund and T. Rowe Price
Associates, Inc. (the Manager) provides for an annual investment management fee,
of which  $1,313,000 was payable at December 31, 1995. The fee is computed daily
and paid  monthly,  and  consists  of an  Individual  Fund Fee equal to 0.35% of
average daily net assets and a Group Fee. The Group Fee is based on the combined
assets of certain  mutual funds  sponsored by the Manager or Rowe  Price-Fleming
International,  Inc.  (the Group).  The Group Fee rate ranges from 0.48% for the
first $1  billion  of assets to 0.31% for  assets in excess of $34  billion.  At
December 31, 1995, and for the year then ended,  the effective  annual Group Fee
rate was  0.34%.  The fund  pays a pro rata  share of the Group Fee based on the
ratio of its net assets to those of the Group.

     In addition,  the fund has entered into agreements with the Manager and two
wholly owned  subsidiaries  of the Manager,  pursuant to which the fund receives
certain other services. The Manager computes the daily share price and maintains
the financial  records of the fund. T. Rowe Price Services,  Inc., is the fund's
transfer  and  dividend   disbursing   agent  and   provides   shareholder   and
administrative  services to the fund. T. Rowe Price  Retirement  Plan  Services,
Inc., provides  subaccounting and recordkeeping  services for certain retirement
accounts  invested in the fund.  The fund  incurred  expenses  pursuant to these
related party agreements  totaling  approximately  $3,691,000 for the year ended
December 31, 1995, of which $397,000 was payable at period-end.

================================================================================
<PAGE>
<TABLE>
                              Financial Highlights
- --------------------------------------------------------------------------------
<S>                                           <C>     <C>           <C>        <C>         <C> 
                                               T. Rowe Price Science & Technology Fund
                                            For a share outstanding throughout each period
                                                       Year Ended December 31,
                                              1995      1994        1993      1992        1991
                                         ------------------------------------------------------
NET ASSET VALUE, BEGINNING OF PERIOD        $21.64   $18.95       $17.33    $15.57      $10.05
                                            ------   ------       ------    ------      ------
Investment activities
  Net investment income                     (0.03)   (0.09)       (0.05)*   (0.10)*     (0.01)*
  Net realized and unrealized gain(loss)    12.05     3.08         4.18      2.98        6.01
                                            ------  ------        ------    ------      ------
Total from investment activities            12.02     2.99         4.13      2.88        6.00
                                            ------  ------        ------    ------      ------
Distributions
  Net investment income                        --       --           --        --          --
  Net realized gain                         (4.54)   (0.30)       (2.51)    (1.12)      (0.48)
                                            ------  ------        ------    ------      ------
Total distributions                         (4.54)   (0.30)       (2.51)    (1.12)      (0.48)
                                            ------  ------        ------    ------      ------
NET ASSET VALUE, END OF PERIOD.            $29.12   $21.64       $18.95    $17.33      $15.57
                                           ======  ======       ======    ======      ======
RATIOS/SUPPLEMENTAL DATA
Total return                                55.5%    15.8%        24.2%*    18.8%*      60.2%*
Ratio of expenses to average net assets     1.01%    1.11%        1.25%*    1.25%*      1.25%*
Ratio of net investment income to 
     average net assets                   (0.15)%  (0.58)%      (0.68)%*  (0.81)%*    (0.07)%*
Portfolio turnover rate                    130.3%   113.3%       163.4%    144.3%      148.2%
Net assets,end of period(in thousands) $2,285,263 $915,052     $501,454  $281,045    $166,048
- --------------------------------------------------------------------------------
<FN>
*  Excludes expenses in excess of a 1.25% voluntary expense limitation in effect
   through December 31, 1993.
</FN>
</TABLE>

================================================================================

<PAGE>

                        Report of Independent Accountants
- --------------------------------------------------------------------------------

To the Shareholders and Board of Directors of
T. Rowe Price Science & Technology Fund, Inc.

     We have audited the accompanying  statement of assets and liabilities of T.
Rowe  Price  Science  &  Technology  Fund,  Inc.,  including  the  portfolio  of
investments,  as of December 31, 1995,  and the related  statement of operations
for the year then ended,  the statement of changes in net assets for each of the
two years in the period then ended, and the financial highlights for each of the
five years in the period then ended.  These  financial  statements and financial
highlights are the responsibility of the Fund's  management.  Our responsibility
is to express an opinion on these financial  statements and financial highlights
based on our audits.

     We conducted  our audits in accordance  with  generally  accepted  auditing
standards.  Those standards require that we plan and perform the audit to obtain
reasonable  assurance  about  whether the  financial  statements  and  financial
highlights are free of material misstatement.  An audit includes examining, on a
test basis,  evidence  supporting  the amounts and  disclosures in the financial
statements.  Our procedures  included  confirmation  of investments  owned as of
December 31, 1995, by correspondence  with the custodia n and brokers.  An audit
also includes assessing the accounting principles used and significant estimates
made by  management,  as well as  evaluating  the  overall  financial  statement
presentation.  We believe  that our audits  provide a  reasonable  basis for our
opinion.

     In our opinion, the financial statements and financial highlights, referred
to above, present fairly, in all material respects, the financial position of T.
Rowe Price Science & Technology  Fund, Inc. as of December 31, 1995, the results
of its  operations,  the changes in its net assets and financial  highlights for
each of the respective  periods stated in the first paragraph in conformity with
generally accepted accounting principles.


COOPERS & LYBRAND L.L.P.


Baltimore, Maryland
January 18, 1996


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