PRICE T ROWE SCIENCE & TECHNOLOGY FUND INC
N-30D/A, 1997-02-06
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                                  ANNUAL REPORT
- --------------------------------------------------------------------------------

                           Science and Technology Fund

- --------------------------------------------------------------------------------

                               December 31, 1996

================================================================================


Report Highlights
- --------------------------------------------------------------------------------


Report Highlights

o    After an  exuberant  1995,  the stock market had another good year in 1996,
     rising more than 20%.

o    Despite  a  difficult  environment  and  midyear  correction,  science  and
     technology  stocks provided good returns,  though not as lofty as the broad
     market.

o    Your fund returned  7.96% and 14.23% for the 6- and 12-month  periods ended
     December 31, trailing similar funds and the overall market.
<PAGE>

o    Over the  last  six  months,  we  increased  fund  exposure  to  electronic
     technology and data services  companies,  while trimming positions in media
     and telecommunications as well as life sciences and health care.

o    Technology  stocks should benefit from strong  industry  product cycles and
     earnings in 1997, and we are positive over the intermediate term.


Fellow Shareholders
- --------------------------------------------------------------------------------

     Despite a difficult  environment for science and technology  stocks earlier
in the year and a  midyear  correction,  your  fund  delivered  strong  absolute
results in 1996,  generating positive returns each quarter and rising 14.23% for
the year.  While the fund held its own during the first half, it lagged both the
unmanaged  Standard  & Poor's 500 Stock  Index and the  Lipper  index of similar
funds over the last six months. Consequently, for the first time since 1988, the
fund trailed both benchmarks for the calendar year.

================================================================================
Performance Comparison
- --------------------------------------------------------------------------------
Periods Ended 12/31/96                  6 Months            12 Months
- --------------------------------------------------------------------------------
Science & Technology Fund                   7.96%               14.23%

S&P 500                                    11.68                22.96

Lipper Science & Technology Fund Index     12.62                16.91
================================================================================


     As always, we remind shareholders that while the fund may be quite volatile
over the short run, it has the potential for superior capital  appreciation over
the long haul.  Our commitment to building  long-term  value is evidenced by the
fund's  cumulative  return of 203% for the five-year  period ended  December 31,
1996, an annualized  average of 24.86%. We will work diligently to continue this
record.

CAPITAL GAIN DISTRIBUTION

     Your fund's Board of Directors  declared a total capital gain  distribution
of  $3.60  per  share  for  1996.  This  distribution,  payable  December  30 to
shareholders  of record on December 26,  reflected a short-term  capital gain of
$0.92 and a long-term capital gain of $2.68. Your check or statement  confirming
the distribution was mailed in early January,  and Form 1099-DIV,  with complete
tax information, was mailed later in the month.
<PAGE>

MARKET ENVIRONMENT

     On the heels of an exhilarating 1995, the overall U.S. stock market enjoyed
another  outstanding year in 1996,  bringing its two-year advance to 69%, one of
the greatest in history. The market shrugged off an array of concerns last year,
including  fears over inflation and rising  interest  rates,  midyear  corporate
earnings  disappointments,  a  flood  lower-quality  initial  public  offerings,
national election anxiety,  and steadily  increasing market  valuations.  Equity
markets rose to record levels,  buoyed by a favorable  economy and unprecedented
cash flows into domestic equity mutual funds.

     Bigger was  definitely  better in 1996 as  investors  sought  the  relative
safety of larger-capitalization, blue chip companies. As shown in the table, the
30 corporate giants that compose the Dow Jones Industrial Average  significantly
outpaced small-company stocks as represented by the Russell 2000 Index. The move
into blue chips was fueled by concern over slowing corporate  earnings growth, a
record year for mergers and  acquisitions  (including  several  megadeals in the
telecommunications  and pharmaceutical  industries),  and a consistent flight to
quality.

================================================================================
Market Performance
- --------------------------------------------------------------------------------
Major Stock Market Indices                                  1996 Return
- --------------------------------------------------------------------------------
Dow Jones Industrial Average                                      28.88%

S&P 500 Index                                                     22.96

Nasdaq Composite *                                                22.71

S&P 400 MidCap Index                                              19.20

Russell 2000                                                      16.49
- --------------------------------------------------------------------------------
*Principal only
================================================================================

     Science and technology  stocks languished during the first half of the year
due  to  several  factors:   eroding   fundamentals  in  the  semiconductor  and
semiconductor capital equipment segments,  modestly disappointing unit growth in
personal computers,  slowing subscriber growth and profitability in the wireless
arena,  and  the  negative  translation  effects  of  a  stronger  U.S.  dollar.
Disappointing   financial   results  became  more  common,   especially  in  the
semiconductor, consumer software, and wireless communications segments.

     Technology   stocks  bottomed  in  July  after  sustaining  their  sharpest
correction  since the spring of 1994.  On a positive  note,  the severity of the
correction helped shake some of the speculative ownership out of the sector. The
sector  recovered  sharply  in the  second  half  of  the  year,  boosted  by an
improvement in the broader market, strong cash flows into domestic equity funds,
hopes for a cyclical recovery in the semiconductor segment,  anticipation of the
normal  seasonal  pickup in personal  computer sales,  and  particularly  strong
performance  from the  major  pharmaceutical  companies.  Many  segments  of the
technology sector advanced more than 40% from their July lows.
<PAGE>

     The technology sector can look forward to strong industry product cycles in
1997.   Intel  should  be   increasing   shipments   of  its  next-   generation
microprocessor,  the  PentiumPro,  while  Microsoft  should be  rolling  out new
versions  of its key product  families  and further  leveraging  its  leadership
position in the software industry.

==============================
The technology sector can look
forward  to  strong   industry
product cycles in 1997.
- ------------------------------

     As the role of the personal computer continues to shift from data device to
communications tool, demand will continue to grow for high-speed  networking and
remote/on-line  access,  portending  continued  strength in the data  networking
segment. While the availability of personal  communications services and digital
cellular  technology  should  usher  in a  period  of  increased  infrastructure
spending   and  a  focus  on   subscriber   growth   in  the   wireless   arena,
telecommunications  reform  remains a source of  uncertainty  for most  wireline
providers.

     Information  services  companies  should  benefit from the corporate  drive
toward outsourcing nonstrategic  administrative  activities, and well-positioned
life sciences and health care companies continue to benefit from the needs of an
aging population,  the shift toward managed care, and the promotion of health at
home and at work.

     Although this improved  environment has already been reflected  somewhat in
the sharp recovery of technology stocks in recent months, we remain enthusiastic
about the sector over the intermediate term.

PORTFOLIO REVIEW

     Our  investments  in  semiconductor,   networking,  and  business  software
companies had the biggest  positive  impact on fund  performance.  In fact,  the
fund's top 10 performers for the year came from these three segments. Enterprise
software vendor BMC Software,  Intel,  data networking  leader 3Com,  Microsoft,
networking giant Cisco Systems,  and semiconductor  manufacturer  Analog Devices
all were outstanding  contributors for the year. Our holdings in the information
services  and life  sciences  and health  care arena also  boosted  performance.
United  States  Surgical and Boston  Scientific,  both pioneers in less invasive
surgery;  National  Data, a leading  transaction  processor;  and America Online
generated sizable gains over the course of the year.
<PAGE>

     [Edgar  description:  A  pie  chart  showing  industry  diversification  on
12/31/96,  Business  and Consumer  Software,  29%;  Semiconductor-Related,  14%;
Networking, 23%; Hardware/Peripherals, 4%; Life Sciences/Health Care, 6%; Media,
6%; Data Services, 16%; Reserves, 2%.]

     In contrast,  our  investments  in media and  telecommunications  services,
biotechnology, and consumer software hampered performance.  Broderbund Software,
Intuit, and Glenayre  Technologies were notable  underachievers.  Broderbund and
Intuit  suffered from the general  malaise in the consumer  software  segment as
well as the cancellation of new product  launches.  As an equipment  supplier to
the paging industry,  Glenayre  Technologies was hurt by the spillover effect of
that   industry's   deteriorating   profitability   and  by  the  transition  to
next-generation  technologies.  On balance,  the fund's  diversification  buoyed
returns during the first half of the year but dampened results during the second
half.

     Nevertheless,  we  remain  comfortable  with  our  strategy  of  running  a
diversified,  yet concentrated,  portfolio of science and technology  stocks. At
year-end,  your fund consisted of  approximately  80 individual  holdings spread
among several rapidly growing industry segments.  Electronic technology the blue
sections of the pie chart - remains the largest  commitment,  accounting for 70%
of fund  assets,  up from 60% last  June.  During  the year,  we  broadened  our
holdings in data  services,  increasing  our exposure from 9% to 16%.  Media and
telecommunications  services and life  sciences/health  care  equally  split the
balance of fund assets.  As of December 31, our top 10 positions  accounted  for
approximately 37% of fund assets, while cash represented 2%.

     We are pursuing  opportunities  along the  following  long-term  investment
themes:  the personal  computer as a communications  tool, the insatiable demand
for high-speed connectivity, the growth in digital wireless communications,  the
trend toward corporations outsourcing nonstrategic administrative functions, and
the continuing shift toward managed and otherwise  cost-conscious health care. A
word on each:

o    The  personal  computer  is  evolving  from  a  computational  device  to a
     multimedia  communications  tool.  Users  no  longer  want to  "compute  it
     faster";  they  want to get  connected  and have  access  -- to  databases,
     information  sources,  and each  other.  Accordingly,  the value added in a
     desktop   configuration   is   spreading   into  the  network  of  servers,
     communications software, and networking equipment.

o    The  industry's  continuing  transition  to open,  networked  client-server
     computing  platforms  is the  most  significant  trend  in  the  commercial
     computing marketplace.  This trend is driving application  development away
     from centralized mainframes and proprietary  minicomputers into networks of
     widely distributed  desktop  workstations.  In addition,  remote access and
     telecommuting   are  becoming   accepted   practices   in  the   workplace.
     Furthermore,  on-line access and use of the public Internet are "must-have"
     applications  in the  consumer  market.  All of these  forces  are  driving
     exponential demand for high-speed connectivity.
<PAGE>

o    Digital  technologies  are just now  beginning to  meaningfully  affect the
     wireless   communications   industry.   Whether   it's  in  the   guise  of
     cellular-like voice services, paging, or satellite video services, wireless
     communications  are making a rapid shift toward digital  technologies.  Our
     focus continues to be on companies with significant international presences
     and those that play critical  roles in the  deployment  of  next-generation
     services.

o    By concentrating on their core value added,  while outsourcing  noncritical
     administrative functions, corporations can reduce costs and risk and remain
     more responsive to customers. In this area, we are concentrating on leading
     companies  that  possess  economies  of scale,  a high  level of  recurring
     revenues, and potential operating leverage.

o    As the link  between  the  patient  and the  medical  bill payor  tightens,
     managed  care and other  forms of  cost-effective  health care will gain in
     popularity. Despite the tougher pricing environment this scenario suggests,
     companies  that  provide  lower-cost  treatment  or that help  measure  and
     competitively analyze treatment outcomes stand to benefit.

OUTLOOK

     After a challenging 1996, science and technology stocks should benefit from
strong  industry  product cycles this year. Our  bullishness is tempered only by
the near-perfect  conditions currently underlying the broader financial markets:
modest inflation and benign interest rates,  steady  corporate  earnings growth,
strong cash flows into domestic  equity mutual funds,  and relative world peace.
Any sudden  change in any of these could  undermine  the stock market in general
and the more volatile science and technology sector in particular.

     While the sharp recovery in both stock prices and investor sentiment during
the  fall  has  somewhat  anticipated  an  improved  environment  in  1997,  our
enthusiasm  about the long-term  potential of the science and technology  sector
remains undiminished.

Respectfully submitted,


[Signature]


Charles A. Morris
President and Chairman of the Investment Advisory Committee

January 17, 1997
<PAGE>

================================================================================
Sticking To Your Game Plan
- --------------------------------------------------------------------------------

   
     [An 8-bar chart showing best and worst  annualized  total returns of stocks
for various rolling time periods between 1950 and 1996]
    

     In our report to you one year ago, we mentioned the possibility of a modest
decline in stock prices.  In fact,  from May to July 1996,  the broad market (as
measured by the Standard & Poor's 500 Stock Index) fell around 7%. However,  the
bull market resumed its charge to post a robust 23% gain for the year.

     Some  believe the market is poised for a  significant  downturn.  We do not
expect a major drop in stock prices in 1997, although another modest pullback is
possible. On balance, we expect stocks to advance at a much slower pace.

     How should you prepare  for a potential  market  pullback?  As always,  our
advice is to diversify  your  investments  and focus on the long term. If you've
implemented  a  sound  investment  strategy,   stay  the  course.   Stocks  have
historically  overcome periods of volatility to provide better returns than most
other investments. Market corrections can even have a silver lining because they
result in good buying opportunities.

     Furthermore,   the  volatility  of  stock  market  returns  has  diminished
significantly  over  longer  time  frames.  The  chart  shows the best and worst
annualized  returns on stocks over various rolling time periods between 1950 and
1996.  (For  instance,  there  were  37  rolling  10-year  periods:   1950-1960,
1951-1961,  etc.)  Investors who held stocks for only one year could have had as
much as a 52.6% gain,  or as little as a 26.5% loss -- a spread of 79 percentage
points. However,  investors who held stocks for 10-year periods or longer always
overcame interim volatility to post gains for the entire period.

In addition,  a well-diversified  portfolio can weather volatility better than a
more  concentrated  portfolio over the long term and particularly  during market
corrections. For example, during last summer's correction,  small-company stocks
fell nearly 16% while  large-company  issues dropped 7.3%.  However, a portfolio
diversified  among large U.S.  companies (30% of assets),  small U.S.  companies
(15%),  foreign  companies  (15%),  intermediate-term  Treasury bonds (30%), and
Treasury bills (10%) would have lost a smaller 5.2% of its value. {1}

Above all,  remember  that  investing is a  long-distance  race,  not a
sprint.

{1} Ned Davis Research.
<PAGE>

================================================================================
Portfolio Highlights
================================================================================
TWENTY-FIVE LARGEST HOLDINGS
- --------------------------------------------------------------------------------
                                                                      Percent of
                                                                      Net Assets
                                                                        12/31/96
- --------------------------------------------------------------------------------
BMC Software                                                                5.1%
3Com                                                                        5.0
Oracle                                                                      4.4
Cisco Systems                                                               3.9
Intel                                                                       3.2
- --------------------------------------------------------------------------------
Analog Devices                                                              3.1
America Online                                                              3.0
Microsoft                                                                   3.0
Maxim Integrated Products                                                   3.0
First Data                                                                  2.8
- --------------------------------------------------------------------------------
Xilinx                                                                      2.6
Synopsys                                                                    2.4
Electronic Data Systems                                                     2.0 
ADC Telecommunications                                                      1.9 
Ascend Communications                                                       1.9
- --------------------------------------------------------------------------------
Network General                                                             1.7 
Linear Technology                                                           1.7 
Boston Scientific                                                           1.5 
FORE Systems                                                                1.5
Shiva                                                                       1.5 
- --------------------------------------------------------------------------------
COMPAQ Computer                                                             1.5 
Newbridge  Networks                                                         1.5 
Glenayre  Technologies                                                      1.3
Automatic Data Processing                                                   1.3 
PanAmSat                                                                    1.3 
- --------------------------------------------------------------------------------
Total                                                                      62.1%
================================================================================
<PAGE>


================================================================================
Portfolio Highlights
- --------------------------------------------------------------------------------
CONTRIBUTIONS TO THE CHANGE IN NET ASSET VALUE PER SHARE
- --------------------------------------------------------------------------------
6 Months Ended December 31, 1996
Ten Best Contributors
- --------------------------------------------------------------------------------
3Com                                                                    65(cent)
Intel                                                                   61
Maxim Integrated Products                                               47
BMC Software                                                            40
Analog Devices                                                          30
Microsoft                                                               28
Linear Technology                                                       23
Boston Scientific                                                       15
Altera **                                                               15
Xilinx                                                                  14
- --------------------------------------------------------------------------------
Total                                                                  338(cent)

================================================================================
Ten Worst Contributors
- --------------------------------------------------------------------------------
Glenayre Technologies                                                  -41(cent)
Shiva                                                                   22
Intuit                                                                  21
Sybase **                                                               14
Omnipoint                                                                9
First Data                                                               8
Newbridge Networks *                                                     8
ADC Telecommunications *                                                 7  
Hewlett-Packard **                                                       6
Broderbund Software **                                                   6
Total                                                                 -142(cent)

================================================================================
<PAGE>

================================================================================
12 Months Ended December 31, 1996
Ten Best Contributors 
- --------------------------------------------------------------------------------

BMC Software                                                            96(cent)
Intel *                                                                 82
3Com                                                                    71 
Cisco Systems                                                           46
Microsoft *                                                             43
Analog Devices                                                          37
Xilinx                                                                  33
PeopleSoft                                                              29
Ascend Communications                                                   28
Cascade Communications                                                  25
- --------------------------------------------------------------------------------
Total                                                                  490(cent)
================================================================================
Ten Worst Contributors
- --------------------------------------------------------------------------------
Intuit                                                                 -55(cent)
Adobe Systems                                                           45 
Broderbund Software **                                                  42
Glenayre Technologies *                                                 40
Bay Networks **                                                         33
Sybase **                                                               31
Quantum **                                                              22 
Mobile Telecom. Technologies **                                         18
Cephalon **                                                             12
Seagate Technology **                                                   10
- --------------------------------------------------------------------------------
Total                                                                 -308(cent)

 *   Position added
**   Position eliminated
================================================================================
<PAGE>

Performance Comparison

     This chart shows the value of a hypothetical $10,000 investment in the fund
over the past 10 fiscal  year  periods or since  inception  (for  funds  lacking
10-year  records).  The result is compared with a broad-based  average or index.
The index return does not reflect  expenses,  which have been  deducted from the
fund's return.

[SEC Chart for Science and Technology Fund]

Average Annual Compound Total Return

     This table shows how the fund would have  performed each year if its actual
(or  cumulative)  returns  for the  periods  shown had been earned at a constant
rate.

================================================================================
                                                                 Since Inception
Periods  Ended  12/31/96        1 Year   3 Years   5 Years   Inception      Date
Science & Technology Fund      14.23%    27.18%     24.86%      21.72%   9/30/87
- --------------------------------------------------------------------------------
Investment  return and principal value represent past performance and will vary.
Shares may be worth more or less at redemption than at original purchase.
================================================================================

<PAGE>
<TABLE>

                                                                     For a share outstanding throughout each period
====================================================================================================================================
Financial Highlights
<CAPTION>
                                                       Year
                                                      Ended
                                                   12/31/96         12/31/95         12/31/94         12/31/93         12/31/92
<S>                                                     <C>              <C>              <C>              <C>              <C>
NET ASSET VALUE
Beginning of period .....................        $    29.12       $    21.64       $    18.95       $    17.33       $    15.57

Investment activities
    Net investment income ...............             (0.09)           (0.03)           (0.09)           (0.05)*          (0.10)*
    Net realized and
    unrealized gain (loss) ..............              4.28            12.05             3.08             4.18             2.98

    Total from
    investment activities ...............              4.19            12.02             2.99             4.13             2.88

Distributions
    Net realized gain ...................             (3.60)           (4.54)           (0.30)           (2.51)           (1.12)

NET ASSET VALUE
End of period ...........................        $    29.71       $    29.12       $    21.64       $    18.95       $    17.33

Ratios/Supplemental Data
Total return ............................             14.23%           55.53%           15.79%           24.25%*          18.76%*

Ratio of expenses to
average net assets ......................              0.97%            1.01%            1.11%            1.25%*           1.25%*

Ratio of net investment
income to average
net assets ..............................             (0.33)%          (0.15)%          (0.58)%          (0.68)%*         (0.81)%*

Portfolio turnover rate .................             125.6%           130.3%           113.3%           163.4%           144.3%

Average commission
rate paid ...............................        $   0.0537               --               --               --               -- 

Net assets, end of period
(in millions) ...........................        $    3,292       $    2,285           $  915            $ 501           $  281
- ------------------------------------------------------------------------------------------------------------------------------------
<FN>
* Excludes expenses in excess of a 1.25% voluntary expense  limitation in effect
through 12/31/93.
</FN>
</TABLE>
The accompanying notes are an integral part of these financial statements.

<PAGE>

================================================================================
Statement of Net Assets
- --------------------------------------------------------------------------------
                                                           Shares/Par     Value

In thousands

Common Stocks  98.0%
ELECTRONIC TECHNOLOGY  68.7%
Business Software  22.2%

Aurum Software * .............................         125,000 $           2,883
BMC Software * ...............................         4,000,000         166,250
Citrix Systems * .............................           500,000          19,531
Cognos * .....................................           706,500          19,782
Informix * ...................................         1,000,000          20,437
INSO * .......................................           500,000          19,688
Microsoft * ..................................         1,200,000          99,225
Netscape Communications * ....................           400,000          22,750
Oracle * .....................................         3,500,000         145,906
PeopleSoft * .................................           750,000          35,953
PLATINUM technology * + ......................         3,000,000          40,687
Pure Atria * .................................         1,300,000          31,931
Rational Software * ..........................           500,000          19,781
Remedy * .....................................           325,000          17,388
SELECT Software Tools ADR * ..................           290,500           5,175
Sterling Software ............................         1,206,000          38,140
Vantive * ....................................           781,400          24,321
                                                                         729,828

Consumer Multimedia and Technical  5.8%

Adobe Systems ...............................            750,000          28,078
Cadence Design Systems * ....................            800,000          31,800
EPIC * + ....................................            750,000          18,750
Intuit * ....................................          1,000,000          31,750
Synopsys * ..................................          1,750,000          80,500
                                                                         190,878
Semiconductor  14.3%

ANADIGICS * ..................................            50,000           1,975
Analog Devices * .............................         3,000,000         101,625
DSP Communications * .........................         1,257,900          24,293
Intel ........................................           800,000         104,750
Linear Technology ............................         1,250,000          54,844
Maxim Integrated Products * ..................         2,250,000          97,453
Xilinx * .....................................         2,350,000          86,510
                                                                         471,450
<PAGE>


Networking  22.2%

3Com * ........................................        2,250,000        $164,953
ADC Telecommunications * ......................        2,000,000          62,250
Ascend Communications * .......................        1,000,000          62,125
Cascade Communications * ......................          500,000          27,625
Cisco Systems * ...............................        2,000,000         127,375
FORE Systems * ................................        1,500,000          49,406
Glenayre Technologies * .......................        2,000,000          43,125
Network General * .............................        1,825,000          55,092
Newbridge Networks * ..........................        1,700,000          48,025
Premisys Communications * .....................          404,000          13,635
Security Dynamics Technologies * ..............          771,200          24,245
Shiva * .......................................        1,400,000          48,650
Summa Four * ..................................          150,000           1,266
Verilink * ....................................          100,000           3,262
                                                                         731,034
Hardware/Peripherals  4.2%

Adaptec * ................................             600,000            24,038
COMPAQ Computer * ........................             650,000            48,262
Dell Computer * ..........................             745,800            39,667
Sun Microsystems * .......................           1,000,000            25,688
                                                                         137,655

Total Electronic Technology 2,260,845
LIFE SCIENCES AND HEALTH CARE  6.1%

Pharmaceuticals  1.0%

ALZA (Class A) * ........................             187,800              4,859
Amgen * .................................             500,000             27,219
                                                                          32,078

Medical Devices  3.9%

Boston Scientific * ......................             850,000            51,000
Stryker ..................................           1,200,000            35,925
United States Surgical ...................           1,054,500            41,521
                                                                         128,446

Health Care Services  1.2%

Medic Computer Systems * ..................          1,000,000            40,312
                                                                          40,312

Total Life Sciences and Health Care                                      200,836
<PAGE>

INFORMATION SERVICES  15.0%
Data Services  15.0%

America Online * .............................         3,000,000         $99,750
Automatic Data Processing ....................         1,000,000          42,875
Cambridge Technology Partners * ..............           500,000          16,781
Checkfree * ..................................         1,471,700          25,111
CUC International * ..........................         1,250,000          29,688
Electronic Data Systems ......................         1,500,000          64,875
First Data ...................................         2,500,000          91,250
Gartner Group * ..............................           424,800          16,541
ITG * ........................................           800,000          15,200
National Data ................................           700,000          30,450
Renaissance Solutions * ......................            58,500           2,654
Sterling Commerce * ..........................           500,000          17,625
SunGard Data Systems * .......................         1,000,000          39,875
Total Information Services ...................           492,675

MEDIA/TELECOMMUNICATIONS SERVICES  5.2%
Media/Telecom Services  5.2%

AirTouch Communications * .............................     1,250,000     31,563
EchoStar Communications (Class A) * ...................       500,000     11,188
Millicom International Cellular * .....................       526,700     16,887
Omnipoint * ...........................................     2,000,000     38,375
PanAmSat * ............................................     1,500,000     42,187
Vodafone ADR ..........................................       800,000     33,100

Total Media/Telecommunications Services                                  173,300

Miscellaneous Common Stocks  3.0%                                         98,293

Total Common Stocks (Cost $2,670,750)                                  3,225,949

Short-Term Investments  3.6%
Federal Home Loan Mortgage Discount Notes

         5.21%, 1/2/97 .................            20,000,000            19,997
         5.23%, 1/3/97 .................            25,000,000            24,993
         5.24%, 1/14/97 ................            20,000,000            19,962

Federal National Mortgage Association Discount Notes
5.27%, 1/10 - 2/18/97 ...................           45,000,000           $44,827
<PAGE>

Investments in Repurchase Agreements through a joint account
6.52%, 1/2/97 ..........................             7,929,752             7,930

Total Short-Term Investments (Cost $117,709)                             117,709

Total Investments in Securities
101.6% of Net Assets (Cost $2,788,459)                               $ 3,343,658

Other Assets Less Liabilities                                           (51,861)

NET ASSETS                                                           $ 3,291,797
Net Assets Consist of:

Accumulated net realized gain/loss - 
net of distributions                                                    $ 14,106

Net unrealized gain (loss)                                               555,199

Paid-in-capital  applicable to 110,798,733 
shares of $0.01 par value capital stock  
outstanding;  1,000,000,000  shares authorized                         2,722,492

NET ASSETS                                                           $ 3,291,797

NET ASSET VALUE PER SHARE $ 29.71

*    Non-income producing
+    Affiliated company

The accompanying notes are an integral part of these financial statements.

<PAGE>

================================================================================
Statement of Operations
- --------------------------------------------------------------------------------
                                                                    In thousands
                                                                            Year
                                                                           Ended
                                                                        12/31/96
- --------------------------------------------------------------------------------
Investment Income

Income
    Interest ...................................................      $  13,943
    Dividend (net of foreign taxes of $ 336) ...................          4,699
    Total income ...............................................         18,642

Expenses
    Investment management ......................................         19,792
    Shareholder servicing ......................................          7,309
    Registration ...............................................            449
    Prospectus and shareholder reports .........................            437
    Custody and accounting .....................................            242

    Directors ..................................................             29
    Legal and audit ............................................             27
    Miscellaneous ..............................................             31
    Total expenses .............................................         28,316

Net investment income ..........................................         (9,674)

Realized and Unrealized Gain (Loss)

Net realized gain (loss) on
    Securities .................................................        274,413
    Foreign currency transactions ..............................           (244)
    Net realized gain (loss) ...................................        274,169
    Change in net unrealized gain or loss on securities ........        104,193

Net realized and unrealized gain (loss) ........................        378,362

INCREASE (DECREASE) IN NET
ASSETS FROM OPERATIONS .........................................      $ 368,688

The accompanying notes are an integral part of these financial statements.
================================================================================
<PAGE>


================================================================================
Statement of Changes in Net Assets
- --------------------------------------------------------------------------------
                                                                    In thousands
                                                       Year
                                                      Ended 
                                                   12/31/96       12/31/95
- --------------------------------------------------------------------------------
Increase (Decrease) in Net Assets

Operations
    Net investment income ...................      $ (9,674)     $  (2,531)
    Net realized gain (loss) ................       274,169        389,644
    Change in net unrealized gain or loss ...       104,193        293,586
    Increase (decrease) in net assets
    from operations .........................       368,688        680,699

Distributions to shareholders
    Net realized gain .......................      (356,162)      (308,443)

Capital share transactions *
    Shares sold .............................     1,604,115      1,486,892
    Distributions reinvested ................       346,237        300,634
    Shares redeemed .........................      (956,344)      (789,571)
    Increase (decrease) in net assets
     from capitalshare transactions .........       994,008        997,955

Net Assets

Increase (decrease) during period ...........     1,006,534      1,370,211
Beginning of period .........................     2,285,263        915,052

End of period ...............................   $ 3,291,797    $ 2,285,263

*Share information
    Shares sold .............................        51,910         53,440
    Distributions reinvested ................        11,502         10,317
    Shares redeemed .........................       (31,097)       (27,563)
    Increase (decrease) in shares outstanding        32,315         36,194

The accompanying notes are an integral part of these financial statements.
================================================================================
<PAGE>

================================================================================
Notes to Financial Statements
- --------------------------------------------------------------------------------

NOTE 1 - SIGNIFICANT ACCOUNTING POLICIES
- --------------------------------------------------------------------------------

     T. Rowe Price  Science & Technology  Fund,  Inc.  (the fund) is  registered
under the Investment Company Act of 1940 as a diversified,  open-end  management
investment company and commenced operations on September 30, 1987.

Valuation

     Equity securities  listed or regularly traded on a securities  exchange are
valued at the last quoted  sales price at the time the  valuations  are made.  A
security  which is listed or traded on more than one  exchange  is valued at the
quotation on the exchange determined to be the primary market for such security.
Listed securities not traded on a particular day and securities regularly traded
in the  over-the-counter  market  are  valued at the mean of the  latest bid and
asked prices. Other equity securities are valued at a price within the limits of
the latest bid and asked prices deemed by the Board of Directors,  or by persons
delegated by the Board, best to reflect fair value.

     Short-term debt  securities are valued at their amortized cost which,  when
combined with accrued interest, approximates fair value.

     Assets  and  liabilities  for  which  the above  valuation  procedures  are
inappropriate  or are deemed not to reflect  fair value are stated at fair value
as determined in good faith by or under the  supervision  of the officers of the
fund, as authorized by the Board of Directors.

Affiliated Companies

     Investments in companies 5% or more of whose outstanding  voting securities
are held by the fund are defined as "Affiliated Companies" in Section 2(a)(3) of
the Investment Company Act of 1940.

Currency Translation

     Assets and liabilities  are translated into U.S.  dollars at the prevailing
exchange  rate  at the end of the  reporting  period.  Purchases  and  sales  of
securities  and income and  expenses  are  translated  into U.S.  dollars at the
prevailing  exchange  rate on the  dates of such  transactions.  The  effect  of
changes in foreign exchange rates on realized and unrealized  security gains and
losses is reflected as a component of such gains and losses.
<PAGE>

Premiums and Discounts

     Premiums and discounts on debt  securities are amortized for both financial
reporting and tax purposes.

Other

     Income  and  expenses  are  recorded  on  the  accrual  basis.   Investment
transactions are accounted for on the trade date.  Realized gains and losses are
reported on the identified  cost basis.  Dividend  income and  distributions  to
shareholders  are  recorded  by the fund on the  ex-dividend  date.  Income  and
capital gain  distributions are determined in accordance with federal income tax
regulations  and may differ from those  determined in accordance  with generally
accepted accounting principles.

NOTE 2 - INVESTMENT TRANSACTIONS
- --------------------------------------------------------------------------------

Repurchase Agreements

     The fund, and other affiliated  funds, may transfer  uninvested cash into a
joint account,  the daily aggregate  balance of which is invested in one or more
overnight repurchase agreements  collaterallized by U.S. government  securities.
Collateral is in the possession of the fund's  custodian and is evaluated  daily
by the fund to ensure that its market value  exceeds the  delivery  value of the
repurchase  agreements at maturity.  All repurchase  agreements purchased by the
joint account satisfy the fund's criteria as to quality, yield, and liquidity.

Other

     Purchases  and  sales  of  portfolio  securities,   other  than  short-term
securities, aggregated $4,149,298,000 and $3,331,750,000,  respectively, for the
year ended December 31, 1996.

NOTE 3 - FEDERAL INCOME TAXES
- --------------------------------------------------------------------------------

     No provision for federal income taxes is required since the fund intends to
continue to qualify as a regulated  investment company and distribute all of its
taxable income.

================================================================================
Undistributed net investment income $ .....................           9,674,000
Undistributed net realized gain ...........................          (9,674,000)
- --------------------------------------------------------------------------------
<PAGE>

     In order for the fund's capital accounts and  distributions to shareholders
to  reflect  the  tax   character  of  certain   transactions,   the   following
reclassifications were made during the year ended December 31, 1996. The results
of operations and net assets were not affected by the reclassifications.

     For  federal  income  tax  purposes  the Fund paid  distributions  from net
long-term  capitial gains of  $266,462,713  ($2.69 per share) to shareholders of
record on December 26, 1996. This amount may differ from that cited elsewhere in
this report due to differences in the  calculation  for financial  reporting and
federal income tax purposes.

     At December 31, 1996, the aggregate cost of investments  for federal income
tax and financial reporting purposes was $2,788,459,000, and net unrealized gain
aggregated   $555,199,000,   of  which   $680,913,000   related  to  appreciated
investments and $125,714,000 to depreciated investments.

NOTE 4 - RELATED PARTY TRANSACTIONS
- --------------------------------------------------------------------------------

     The  investment  management  agreement  between  the fund and T. Rowe Price
Associates, Inc. (the manager) provides for an annual investment management fee,
of which  $1,944,000 was payable at December 31, 1996. The fee is computed daily
and paid  monthly,  and  consists  of an  individual  fund fee equal to 0.35% of
average daily net assets and a group fee. The group fee is based on the combined
assets of certain  mutual funds  sponsored by the manager or Rowe  Price-Fleming
International,  Inc.  (the group).  The group fee rate ranges from 0.48% for the
first $1 billion of assets to 0.305%  for  assets in excess of $50  billion.  At
December 31, 1996, and for the year then ended,  the effective  annual group fee
rate was  0.33%.  The fund pays a  pro-rata  share of the group fee based on the
ratio of its net assets to those of the group.

     In addition,  the fund has entered into agreements with the manager and two
wholly owned  subsidiaries  of the manager,  pursuant to which the fund receives
certain other services. The manager computes the daily share price and maintains
the financial  records of the fund. T. Rowe Price  Services,  Inc. (TRPS) is the
fund's  transfer and dividend  disbursing  agent and  provides  shareholder  and
administrative  services to the fund. T. Rowe Price  Retirement  Plan  Services,
Inc., provides  subaccounting and recordkeeping  services for certain retirement
accounts  invested in the fund.  The fund  incurred  expenses  pursuant to these
related party agreements  totaling  approximately  $5,692,000 for the year ended
December 31, 1996, of which $616,000 was payable at period-end.
<PAGE>

================================================================================
Report of Independent Accountants
- --------------------------------------------------------------------------------

To the Shareholders and Board of Directors of T. Rowe Price
Science & Technology Fund, Inc.

     We have audited the  accompanying  statement of net assets of T. Rowe Price
Science &  Technology  Fund,  Inc.  as of  December  31,  1996,  and the related
statement of operations for the year then ended, the statement of changes in net
assets  for each of the two years in the  period  then  ended and the  financial
highlights for each of the five years in the period then ended.  These financial
statements  and  financial  highlights  are  the  responsibility  of the  Fund's
management.  Our  responsibility  is to express  an  opinion on these  financial
statements and financial highlights based on our audits.

     We conducted  our audits in accordance  with  generally  accepted  auditing
standards.  Those standards require that we plan and perform the audit to obtain
reasonable  assurance  about  whether the  financial  statements  and  financial
highlights are free of material misstatement.  An audit includes examining, on a
test basis,  evidence  supporting  the amounts and  disclosures in the financial
statements.  Our procedures  included  confirmation  of investments  owned as of
December 31, 1996, by correspondence with the custodian.  An audit also includes
assessing the  accounting  principles  used and  significant  estimates  made by
management,  as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.

     In our opinion,  the financial statements and financial highlights referred
to above present fairly, in all material respects,  the financial position of T.
Rowe Price Science & Technology  Fund, Inc. as of December 31, 1996, the results
of its  operations,  the changes in its net assets and financial  highlights for
each of the respective periods stated in the first paragraph, in conformity with
generally accepted accounting principles.

COOPERS & LYBRAND L.L.P.
Baltimore, Maryland
January 20, 1997

<PAGE>

                      For yield, price, last transaction,
                         current balance, or to conduct
                         transactions, 24 hours, 7 days
                          a week, call Tele*Access(R):
                            1-800-638-2587 toll free

                                 For assistance
                               with your existing
                              fund account, call:
                           Shareholder Service Center
                            1-800-225-5132 toll free
                            625-6500 Baltimore area

                          To open a Discount Brokerage
                         account or obtain information,
                         call: 1-800-638-5660 toll free

                               Internet address:
                           http://www.troweprice.com

                            T. Rowe Price Associates
                             100 East Pratt Street
                            Baltimore, Maryland 21202

                         This report is authorized for
                        distribution only to shareholders
                        and to others who have received
                        a copy of the prospectus of the
                    T. Rowe Price Science & Technology Fund.

                               Investor Centers:
                              101 East Lombard St.
                              Baltimore, MD 21202

                                 T. Rowe Price
                                Financial Center
                              10090 Red Run Blvd.
                             Owings Mills, MD 21117
<PAGE>

                                Farragut Square
                             900 17th Street, N.W.
                             Washington, D.C. 20006

                                   ARCO Tower
                                   31st Floor
                              515 South Flower St.
                             Los Angeles, CA 90071

                              4200 West Cypress St.
                                   10th Floor
                                 Tampa, FL 33607
              T. Rowe Price Investment Services, Inc., Distributor.
                                RPRTSTF 12/31/96


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