PRICE T ROWE SCIENCE & TECHNOLOGY FUND INC
N-30D, 2000-08-10
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                                 T. Rowe Price
--------------------------------------------------------------------------------
                               Semiannual Report
                            Science & Technology Fund
--------------------------------------------------------------------------------
                                  June 30, 2000
--------------------------------------------------------------------------------
REPORT HIGHLIGHTS
================================================================================
SCIENCE & TECHNOLOGY FUND
-------------------------

     *    The broad stock market produced mixed results during the first half of
          the year.

     *    Fund results lagged the S&P 500 and the Lipper peer group index due to
          our conservative investment posture, although absolute performance was
          strong during the past 12 months.

     *    We built  significant  positions in select emerging leaders during the
          spri ng correction.

     *    While our  near-term  outlook is  somewhat  cautious,  we believe  our
          portfolio  of sound  companies  with  secular  growth  potential  will
          continue to reward shareholders over time.
================================================================================
UPDATES AVAILABLE
-----------------
     For  updates  on T. Rowe Price  funds  following  the end of each  calendar
quarter, please see our Web site at www.troweprice.com.
================================================================================
FELLOW SHAREHOLDERS
-------------------

     The equity markets  delivered  mixed results during the first six months of
the year, although most major indices ended with modest losses.  While investors
remained enthusiastic about global economic growth and corporate earnings, worry
began to build  about  rising  interest  rates and the pace of  future  economic
expansion.  With the Federal Reserve continuing its policy of monetary restraint
by raising  short-term  rates a total of one percentage  point so far this year,
neither  upward  earnings  revisions  nor steady  cash flows into  equity  funds
allowed the broad market to make real progress.  Your fund's  results  reflected
the overall environment.


<PAGE>

       *************************************************************

          PERFORMANCE COMPARISON
          ----------------------
          Periods Ended 6/30/00         6 Months       12 Months
          ---------------------         --------       ---------
          Science &Technology Fund        -2.70%          49.49%
          S&P 500                         -0.43            7.24
          Lipper Science & Technology
          Fund Index                       8.92           82.97

       *************************************************************

     During the first half, the fund fell 2.70%, compared with a return of 8.92%
for the Lipper  Science &  Technology  Fund Index and a decline of 0.43% for the
unmanaged  Standard & Poor's 500 Stock  Index.  For the 12 months ended June 30,
the fund's  49.49%  return far outpaced the S&P 500 but trailed the Lipper index
of similar funds. Our relatively  conservative  investment posture at the end of
1999,   as  well  as  our   continuing   bias  toward   stocks  of   established
larger-capitalization  technology companies, were the primary factors behind the
lagging results versus our peers.

MARKET ENVIRONMENT
------------------
     The first half  marked  one of the most  volatile  periods in stock  market
history,  with the Nasdaq Composite Index moving  intraday,  every day, at least
one percent in one  direction  or another.  With stocks near  historically  high
valuations and liquidity  limited,  news releases and slight changes in investor
sentiment were able to push stock prices around considerably.

     Technology stocks got off to a fast start in 2000. Growth was accelerating,
pricing was firm,  profits were expanding,  the capital markets were charitable,
and the much  ballyhooed  Y2K risk  proved  to be DOA.  However,  as the  period
progressed,   technology  investors  became  increasingly  concerned  about  the
viability  of  Internet  company  business  models,  the cash burn  rates  among
emerging  telecommunications  carriers,  decelerating growth in the wireless and
semiconductor   industries,   and   continued   sluggish   corporate  PC  sales.
Accordingly,  technology stocks corrected  significantly through late May before
staging a sharp rally in early June to finish the six months with modest  gains.
During the period,  standout performers were stocks of communications  equipment
and semiconductor-related companies, while stocks of e-commerce,  communications
services, and software companies fared poorly.


<PAGE>

INVESTMENT PHILOSOPHY
---------------------
     The salient characteristic of our approach is intensive,  timely,  hands-on
research  in  the  areas  of  communications,   integrated  circuits,  software,
computing hardware,  electronic commerce,  information services, media, and life
sciences.  This  involves  extensive  company  visits,  customer and  competitor
interviews,  participation at trade shows and industry symposiums,  and detailed
financial  analysis.  We focus our internal  resources on  developing  insights,
relying on external  resources  primarily  for  information.  Given the inherent
volatility of the fund's universe, we usually maintain a modest cash position to
permit opportunistic purchases.

     Our  investment  philosophy  can  be  summarized  by  the  following  seven
investment principles:

     *    Stay exposed to long-term, secular investment themes.

     *    Diversify  exposure among the most attractive  segments of the science
          and technology sector.

     *    Seek  investments in companies that possess  significant  intellectual
          property.

     *    Concentrate holdings in companies with sustainable business models.

     *    Emphasize companies embarking on meaningful new product cycles.

     *    Seek  companies  whose  management  has both vision and a proven track
          record.

     *    Keep the portfolio fresh.

     These  principles  have important  ramifications  for your fund's  profile.
First,  our stock holdings will be  concentrated  in the secular  themes.  While
individual positions will change frequently, the themes should be more enduring.
Second,  in contrast to most technology  sector funds,  our investments  will be
spread  across a variety  of  segments  within a  broadly  defined  science  and
technology  sector.  Third,  the fund will not  emphasize  stocks  of  companies
selling  commodity  products  in  highly  cyclical  markets.  Fourth,  we prefer
companies  whose destiny  remains more in their own control than in the vagaries
of the markets in which they  participate.  Fifth,  our core holdings will be in
stocks of companies with, in our opinion, extremely capable management. Finally,
in addition to maintaining core positions in established,  leadership companies,
our holdings may include  investments across an array of smaller,  more volatile
companies.


<PAGE>

     By  consistently  applying  these  investment  principles  to the portfolio
management  process,  we hope to ensure  that your fund  remains  exposed to the
best-positioned  companies in the most rapidly  growing areas of the science and
technology  industry.  Our investment approach is aggressive,  and the potential
long-term  rewards  from an  investment  in  this  fund  are  likely  to  entail
considerable price  fluctuations.  However, we firmly believe that over time the
rewards will compensate  shareholders for their risks.  Because the fund's scale
and  diversification  make it unlikely to be the top performer in any particular
quarter, we manage the fund with the objective of generating consistent absolute
and superior relative performance over a longer-term horizon.

PORTFOLIO REVIEW
----------------

     The fund remained  concentrated in the electronic  technology segment, with
essentially all of our assets committed to this area.  Stocks of  communications
equipment,  semiconductors,  and  enterprise  software  companies  dominated our
holdings, representing over half of fund assets on a combined basis. The balance
of  assets  was  diversified   across  an  array  of  other   technology-related
industries.  The fund's 25 largest holdings constituted 75% of portfolio assets,
and the portfolio was essentially fully invested at the end of June, with only a
small cash position.

       *************************************************************

          Sector Diversification pie chart showing Communications
            33%, Semiconductors 26%, Software 20%, Hardware 13%,
                   Information Services 6%, Reserves 2%

       *************************************************************

     During the past six months,  fund performance was most positively  affected
by our holdings in the semiconductor and commu nications equipment segments. Six
of our best-performing stocks were semicondu ctor-related  companies,  including
communications chip vendor ANALOG DEVICES an d programmable logic vendors XILINX
and ALTERA. These companies continue to benefit from the accelerating  build-out
of digital  wireless and data  networks.  Optical  equipment  vendor CIENA and a
restructured  3COM  were  the  best of  several  strong  contributors  from  the
communications   equipment  segment,  while  Internet  software   infrastructure
providers ORACLE and ARIBA were also among the top 10 performers.

     In contrast,  the fund suffered  substantial losses in stocks of enterprise
software  companies that stumbled during their transition from  client-server to
Internet  architectures.   PARAMETRIC  TECHNOLOGY,  NOVELL,  BMC  SOFTWARE,  and
MICROSOFT all reported  disappointing  financial  results during the first half.
The fund also  suffered  from the  spring  e-commerce  meltdown,  as YAHOO!  and
Internet incubators INTERNET CAPITAL GROUP and SOFTBANK declined significantly.


<PAGE>

     During  the  volatile   correction  in  technology   stocks,  we  purchased
significant new positions in Ariba, CIENA,  QUALCOMM,  DOUBLECLICK,  and APPLIED
MICRO  CIRCUITS  in an attempt to improve the growth  profile of the  portfolio.
Notable  eliminations  during the six months  included 3Com  (shortly  after the
public flotation of its PALM subsidiary),  AMERICA ONLINE (immediately after the
announced  merger with Time Warner),  and  Microsoft  (over the dual concerns of
legal challenges and sluggish operating profit growth).  Proceeds from our sales
of WORLDCOM and MOTOROLA  were used to finance  alternative  investments  as the
technology sector corrected.

OUTLOOK
-------

     Whi7le technology  sector  fundamentals  remain excellent,  there are signs
that we are nearing an inflection  point in revenue growth and profit  expansion
across several industry segments,  and valuations remain stubbornly high. Should
these  signs be  confirmed  in the months  ahead,  we would  anticipate  renewed
volatility with a downward bias.  Moreover,  until  investors  conclude that the
Federal  Reserve is finished  raising  interest  rates,  the  broader  market is
unlikely to be a positive catalyst.

     Given  our  somewhat  cautious   near-term  outlook  for  the  science  and
technology  sector,  we will  continue  to  concentrate  our assets in stocks of
leadership  companies  that we believe  possess  the  brightest  secular  growth
opportunities,  while opportunistically  building positions in the stocks of the
most promising emerging companies.  By staying the course and depending upon the
same process and style that generated the strong returns enjoyed by shareholders
over the  lifetime  of the  portfolio,  we hope to extend the fund's  successful
longer-term record.

     As always, we appreciate your continued support.

Respectfully submitted,
Charles A. Morris

/s/

President and Chairman of the Investment Advisory Committee
July 21, 2000



<PAGE>

       *************************************************************

       ADVISOR SHARE CLASS CREATED
       ---------------------------

            T. Rowe  Price has  introduced  a new class of shares for
       certain  funds,  including  this one.  The new  Advisor  Class
       shares will be sold  exclusively by financial  intermediaries,
       such as brokers and financial  advisers,  and will enhance our
       ability  to  reach  a new  group  of  investors  through  this
       expanding  channel.  Since  the new  share  class has a modest
       12b-1 fee (a distribution fee paid to the sales intermediary),
       its  performance  will  likely  vary  somewhat  from your fund
       shares even though both invest in the same portfolio.

            We want to  emphasize  that the new  class  will  have no
       impact  whatsoever  on your  investment  in the fund or on the
       returns provided to you by the fund. The daily net asset value
       and  expenses for the  existing  shares and the Advisor  Class
       shares are calculated separately.  In due course, you will see
       the Advisor Class share prices listed in newspapers  and other
       print and electronic media.  Certain expenses  associated with
       the  Advisor  Class  shares  will  be  itemized  in  financial
       statements in your fund's shareholder reports.

================================================================================
T. Rowe Price Science & Technology Fund
--------------------------------------------------------------------------------
PORTFOLIO HIGHLIGHTS
--------------------
TWENTY-FIVE LARGEST HOLDINGS
----------------------------
                                                                      Percent of
                                                                      Net Assets
                                                                        6/30/00
                                                                     -----------
Oracle                                                                      5.4%
Cisco Systems                                                               4.5
Analog Devices                                                              4.3
Maxim Integrated Products                                                   3.8
Xilinx                                                                      3.8
Vodafone Airtouch                                                           3.8
Ariba                                                                       3.8
Altera                                                                      3.6
CIENA                                                                       3.5
Nokia                                                                       3.5
Nortel Networks                                                             3.4
Sun Microsystems                                                            3.2

<PAGE>

Texas Instruments                                                           2.9
BMC Software                                                                2.6
Applied Materials                                                           2.6
WorldCom                                                                    2.3
VeriSign                                                                    2.2
Applied Micro Circuits                                                      2.1
Dell Computer                                                               2.1
Solectron                                                                   2.1
Electronic Arts                                                             2.1
NEXTLINK Communications                                                     2.0
EMC                                                                         1.9
Intuit                                                                      1.8
QUALCOMM                                                                    1.7
                                                                     -----------
Total                                                                      75.0%

Note: Table excludes reserves.
================================================================================
T. Rowe Price Science & Technology Fund
--------------------------------------------------------------------------------
PORTFOLIO HIGHLIGHTS
--------------------
MAJOR PORTFOLIO CHANGES
-----------------------
Listed in descending order of size

       6 Months Ended 6/30/00
       Ten Largest Purchases                    Ten Largest Sales
       ---------------------                    -----------------

       QUALCOMM *                               3Com  **
       Motorola *                               America Online **
       Ariba *                                  Microsoft **
       3Com                                     Dell Computer
       CIENA *                                  Yahoo! **
       BMC Software                             Motorola **
       WorldCom                                 WorldCom
       Dell Computer                            Intel **
       DoubleClick *                            SCISystems **
       Applied Micro Circuits *                 Conexant Systems **

    *  Position added
   **  Position eliminated
================================================================================

<PAGE>

T. Rowe Price Science & Technology Fund
--------------------------------------------------------------------------------
PERFORMANCE COMPARISON
----------------------
     This chart shows the value of a hypothetical $10,000 investment in the fund
over the past 10 fiscal  year  periods or since  inception  (for  funds  lacking
10-year  records).  The result is compared with benchmarks,  which may include a
broad-based  market index and a peer group average or index.  Market  indexes do
not include  expenses,  which are  deducted  from fund returns as well as mutual
fund averages and indexes.

                   Lipper Science &             S&P 500           Science &
                Technology Fund Index         Stock Index      Technology Fund
                ---------------------         -----------      ---------------
6/30/90                 10,000                   10,000             10,000
6/91                     9,920                   10,739             10,295
6/92                    11,304                   12,180             12,111
6/93                    15,207                   13,840             16,957
6/94                    15,048                   14,034             17,538
6/95                    23,111                   17,694             29,485
6/96                    26,194                   22,294             36,945
6/97                    31,475                   30,030             40,907
6/98                    37,369                   39,088             47,191
6/99                    59,532                   47,983             75,550
6/00                   108,925                   51,459            112,939

AVERAGE ANNUAL COMPOUND TOTAL RETURN
------------------------------------
     This table shows how the fund would have  performed each year if its actual
(or cumulative)returns for the periods shown had been earned at a constant rate.

    Periods Ended 6/30/00            1 Year     3 Years     5 Years     10 Years
    ---------------------            ------     -------     -------     --------
    Science & Technology Fund        49.49%      40.29%      30.81%       27.43%

     Investment  return and principal value represent past  performance and will
vary. Shares may be worth more or less at redemption than at original purchase.
================================================================================

<PAGE>

T. Rowe Price Science & Technology Fund
--------------------------------------------------------------------------------
Unaudited                         For a share outstanding throughout each period
FINANCIAL HIGHLIGHTS
--------------------
SCIENCE & TECHNOLOGY SHARES

                      6 Months      Year
                         Ended     Ended
                       6/30/00  12/31/99  12/31/98  12/31/97  12/31/96  12/31/95
                       -------  --------  --------  --------  --------  --------
NET ASSET VALUE
Beginning of period   $ 63.71   $ 37.67   $ 27.26   $ 29.71   $ 29.12   $ 21.64
--------------------------------------------------------------------------------
Investment activities
 Net investment
 income (loss)          (0.15)    (0.09)    (0.18)    (0.12)    (0.09)    (0.03)
 Net realized and
 unrealized gain (loss) (1.57)    36.85     11.58      0.54      4.28     12.05
--------------------------------------------------------------------------------
 Total from
 investment activiti    (1.72)    36.76     11.40      0.42      4.19     12.02
--------------------------------------------------------------------------------
Distributions
 Net realized gain          -    (10.72)    (0.99)    (2.87)    (3.60)    (4.54)
--------------------------------------------------------------------------------
NET ASSET VALUE
End of period         $ 61.99   $ 63.71   $ 37.67   $ 27.26   $ 29.71   $ 29.12
--------------------------------------------------------------------------------

RATIOS/SUPPLEMENTAL DATA
------------------------
Total return~           (2.70)%  100.99%    42.35%     1.71%    14.23%    55.53%
--------------------------------------------------------------------------------
Ratio of total expenses
to average net assets    0.85%+    0.87%     0.94%     0.94%     0.97%     1.01%
--------------------------------------------------------------------------------
Ratio of net investment
income (loss) to
average net assets      (0.49)%+  (0.26)%   (0.61)%   (0.44)%   (0.33)%  (0.15)%
--------------------------------------------------------------------------------
Portfolio
turnover rate           124.1%+   128.0%    108.9%    133.9%    125.6%    130.3%
--------------------------------------------------------------------------------
Net assets, end of
period (in millions) $ 14,127  $ 12,271   $ 4,696   $ 3,538   $ 3,292   $ 2,285
--------------------------------------------------------------------------------
     ~    Total return  reflects the rate that an investor  would have earned on
          an investment in the fund during each period, assuming reinvestment of
          all distributions.
     +    Annualized

The accompanying notes are an integral part of these financial statements.
================================================================================

<PAGE>

T. Rowe Price Science & Technology Fund
--------------------------------------------------------------------------------
Unaudited                         For a share outstanding throughout each period
FINANCIAL HIGHLIGHTS
--------------------
SCIENCE & TECHNOLOGY ADVISOR CLASS SHARES
                                                                         3/31/00
                                                                         Through
                                                                         6/30/00
                                                                      ----------
NET ASSET VALUE
Beginning of period                                                    $ 71.08
--------------------------------------------------------------------------------
Investment activities
 Net investment income (loss)                                            (0.02)
 Net realized and
 unrealized gain (loss)                                                  (9.05)
--------------------------------------------------------------------------------
 Total from
 investment activities                                                   (9.07)
--------------------------------------------------------------------------------
NET ASSET VALUE
End of period                                                          $ 62.01
--------------------------------------------------------------------------------

RATIOS/SUPPLEMENTAL DATA
------------------------
Total return~                                                           (12.76)%
--------------------------------------------------------------------------------
Ratio of total expenses
to average net assets                                                     0.71%
--------------------------------------------------------------------------------
Ratio of net investment
income (loss) to
average net assets                                                       (0.59)%
--------------------------------------------------------------------------------
Portfolio turnover rate                                                  124.1%
--------------------------------------------------------------------------------
Net assets, end of
period (in thousands)                                                  $ 506
--------------------------------------------------------------------------------
     ~    Total return  reflects the rate that an investor  would have earned on
          an investment in the fund during each period, assuming reinvestment of
          all distributions.
     +    Annualized

The accompanying notes are an integral part of these financial statements.
================================================================================

<PAGE>

T. Rowe Price Science & Technology Fund
--------------------------------------------------------------------------------
Unaudited                                                          June 30, 2000
PORTFOLIO OF INVESTMENTS
------------------------
                                                        Shares           Value
                                                     -----------     -----------
                                                             In thousands
COMMON STOCKS AND WARRANT 97.4%
INFORMATIO SERVICES  5.4%
------------------------
E-COMMERCE  5.4%
DoubleClick *                                          5,300,000      $ 202,062
--------------------------------------------------------------------------------
Internet Capital Group, (144a) *++                     1,000,000         22,163
--------------------------------------------------------------------------------
Internet Capital Group,
(144a), Warrants, 5/10/02 *++                            208,333          7,734
--------------------------------------------------------------------------------
Softbank (JPY)                                         1,550,000        210,358
--------------------------------------------------------------------------------
Verisign *                                             1,800,000        317,419
--------------------------------------------------------------------------------
Total Information Services                                              759,736
                                                                     -----------
SEMICONDUCTORS  26.2%
---------------------
SEMICONDUCTORS & COMPONENTS  20.6%
Altera *                                               5,000,000        509,531
--------------------------------------------------------------------------------
Analog Devices *                                       8,000,000        608,000
--------------------------------------------------------------------------------
Applied Micro Circuits *                               3,000,000        296,250
--------------------------------------------------------------------------------
Maxim Integrated Products *                            8,000,000        543,250
--------------------------------------------------------------------------------
Texas Instruments                                      6,000,000        412,125
--------------------------------------------------------------------------------
Xilinx *                                               6,500,000        536,860
--------------------------------------------------------------------------------
                                                                      2,906,016
                                                                     -----------
SEMICONDUCTOR EQUIPMENT  5.6%
Applied Materials *                                    4,000,000        362,625
--------------------------------------------------------------------------------
ASM Lithography *                                      3,500,000        154,328
--------------------------------------------------------------------------------
Cognex * +                                             2,500,000        129,297
--------------------------------------------------------------------------------
KLA-Tencor *                                           2,500,000        146,484
--------------------------------------------------------------------------------
                                                                        792,734
                                                                     -----------
Total Semiconductors                                                  3,698,750
                                                                     -----------

<PAGE>

COMMUNICATIONS  33.1%
---------------------
COMMUNICATION EQUIPMENT  21.1%
CIENA *                                                3,000,000        499,969
--------------------------------------------------------------------------------
Cisco Systems *                                       10,000,000        635,312
--------------------------------------------------------------------------------
E-Tek Dynamics *                                         500,000        131,875
--------------------------------------------------------------------------------
JDS Uniphase *                                         2,000,000        179,766
--------------------------------------------------------------------------------
LM Ericsson ADR (Class B)                             11,000,000        220,344
--------------------------------------------------------------------------------
Nokia ADR                                             10,000,000        499,375
--------------------------------------------------------------------------------
Nortel Networks                                        7,000,000        477,750
--------------------------------------------------------------------------------
QUALCOMM *                                             4,000,000      $ 239,875
--------------------------------------------------------------------------------
Xircom * +                                             2,000,000         95,062
--------------------------------------------------------------------------------
                                                                      2,979,328
                                                                     -----------
COMMUNICATION SERVICES  12.0%
Colt Telecom Group (GBP) *                             5,500,000        183,751
--------------------------------------------------------------------------------
Exodus Communications *                                4,250,000        195,898
--------------------------------------------------------------------------------
NEXTLINK Communications *                              7,500,000        284,297
--------------------------------------------------------------------------------
PSINet *                                               7,000,000        175,656
--------------------------------------------------------------------------------
Vodafone Airtouch (GBP)                               30,000,000        122,334
--------------------------------------------------------------------------------
Vodafone Airtouch ADR                                 10,000,000        414,375
--------------------------------------------------------------------------------
WorldCom *                                             7,000,000        321,344
--------------------------------------------------------------------------------
                                                                      1,697,655
                                                                     -----------
Total Communications                                                  4,676,983
                                                                     -----------
HARDWARE  12.6%
---------------
PERIPHERALS  2.4%
Electronics for Imaging *                              2,500,000         63,125
--------------------------------------------------------------------------------
EMC *                                                  3,500,000        269,281
--------------------------------------------------------------------------------
                                                                        332,406
                                                                     -----------

<PAGE>

SYSTEMS  5.3%
Dell Computer *                                        6,000,000        296,062
--------------------------------------------------------------------------------
Sun Microsystems *                                     5,000,000        454,844
--------------------------------------------------------------------------------
                                                                        750,906
                                                                     -----------
Contract Manufacturing  4.9%
Flextronics International *                            3,350,000        230,208
--------------------------------------------------------------------------------
Sanmina *                                              2,000,000        170,938
--------------------------------------------------------------------------------
Solectron *                                            7,000,000        293,125
--------------------------------------------------------------------------------
                                                                        694,271
                                                                     -----------
Total Hardware                                                        1,777,583
                                                                     -----------
SOFTWARE  18.5%
---------------
ENTERPRISE SOFTWARE  13.7%
Ariba *                                                5,450,000        534,441
--------------------------------------------------------------------------------
BMC Software *                                        10,000,000        364,687
--------------------------------------------------------------------------------
Liberate Technologies *                                2,000,000         58,688
--------------------------------------------------------------------------------
Oracle *                                               9,000,000        756,281
--------------------------------------------------------------------------------
VERITAS Software *                                     2,000,000        225,937
--------------------------------------------------------------------------------
                                                                      1,940,034
                                                                     -----------
CONSUMER AND MULTI MEDIA SOFTWARE  4.4%
Electronic Arts * +                                    4,000,000      $ 291,875
--------------------------------------------------------------------------------
Intuit *                                               6,000,000        247,875
--------------------------------------------------------------------------------
RealNetworks *                                         1,500,000         75,797
--------------------------------------------------------------------------------
                                                                        615,547
                                                                     -----------
TECHNICAL SOFTWARE  0.4%
Synopsys *                                             1,850,000         63,883
--------------------------------------------------------------------------------
                                                                         63,883
                                                                     -----------
Total Software                                                        2,619,464
                                                                     -----------
Other Miscellaneous Common Stocks 1.6%                                  220,341
                                                                     -----------
Total Common Stocks and Warrants (Cost  $9,835,729)                  13,752,857
                                                                     -----------

<PAGE>

CONVERTIBLE PREFERRED STOCKS  0.7%
----------------------------------
AllAdvantage *ss.++                                    1,239,670          7,500
--------------------------------------------------------------------------------
idealab! (Series D) *ss.++                             1,000,000        100,000
--------------------------------------------------------------------------------

Total Convertible Preferred Stocks (Cost $107,500)                      107,500
                                                                     -----------
SHORT-TERM INVESTMENTS  2.3%
----------------------------
MONEY MARKET FUNDS  2.3%
Government Reserve Investment Fund, 6.27% # +        326,728,183        326,728
--------------------------------------------------------------------------------
Total Short-Term Investments (Cost  $326,728)                           326,728
                                                                     -----------
TOTAL INVESTMENTS IN SECURITIES
100.4% of Net Assets (Cost $10,269,957)                            $ 14,187,085

Other Assets Less Liabilities                                           (59,824)
                                                                     -----------
NET ASSETS                                                         $ 14,127,261
                                                                     -----------
   #  Seven-day yield
   +  Affiliated company
  ++  Securities contain some restrictions as to
      public resale--total of such securities at
      period-end  amounts  to  0.2%  of net  assets.
  ss  Private Placement
   *  Non-income producing
 ADR  American Depository Receipt
 GBP  British sterling
 JPY  Japanese yen
144a  Security  was  purchased  pursuant  to  Rule
      144a  under  the  Securities Act  of 1933 and
      may not be resold subject to that rule except
      to  qualified  institutional buyers--total of
      such  securities  at  period-end  amounts  to
      0.2% of net assets.

The accompanying notes are an integral part of these financial statements.
================================================================================

<PAGE>

T. Rowe Price Science & Technology Fund
Unaudited                                                          June 30, 2000
STATEMENT OF ASSETS AND LIABILITIES
-----------------------------------
In thousands

ASSETS
------
Investments in securities, at value
 Affiliated companies (cost $839,406)                                 $ 842,962
 Other companies (cost $9,430,551)                                   13,344,123
                                                                   -------------
 Total investments in securities                                     14,187,085
Other assets                                                            140,382
                                                                   -------------
Total assets                                                         14,327,467

LIABILITIES
-----------
Total liabilities                                                       200,206
                                                                   -------------
NET ASSETS                                                         $ 14,127,261
                                                                   -------------
NET ASSETS CONSIST OF:
Accumulated net investment income - net of distributions              $ (33,803)
Accumulated net realized gain/loss - net of distributions             1,188,371
Net unrealized gain (loss)                                            3,917,128
Paid-in-capital applicable to 227,878,979 shares of
$0.01 par value capital stock outstanding;
1,000,000,000 shares authorized                                       9,055,565
                                                                   -------------
NET ASSETS                                                         $ 14,127,261
                                                                   -------------
NET ASSET VALUE PER SHARE
Science & Technology shares
($14,126,754,842/227,870,822 shares outstanding)                        $ 61.99
                                                                   -------------
Science & Technology Advisor Class shares
($505,855/8,157 shares outstanding)                                     $ 62.01
                                                                   -------------

The accompanying notes are an integral part of these financial statements.
================================================================================

<PAGE>

T. Rowe Price Science & Technology Fund
--------------------------------------------------------------------------------
Unaudited
STATEMENT OF OPERATIONS
-----------------------
In thousands
                                                                        6 Months
                                                                           Ended
                                                                         6/30/00
                                                                   -------------
INVESTMENT INCOME (LOSS)
------------------------
Income
 Interest (including $14,328 from affiliated companies)                $ 20,806
 Dividend (net of foreign taxes of $468)                                  3,671
                                                                   -------------
 Total Income                                                            24,477
                                                                   -------------
Expenses
 Investment management                                                   45,698
 Shareholder servicing
  Science & Technology shares                                            11,380
  Science & Technology Advisor Class shares                                   -
 Registration                                                               524
 Prospectus and shareholder reports
  Science & Technology shares                                               329
  Science & Technology Advisor Class shares                                   -
 Custody and accounting                                                     297
 Legal and audit                                                             22
 Directors                                                                   15
 Miscellaneous                                                               60
                                                                   -------------
 Total expenses                                                          58,325
 Expenses paid indirectly                                                   (45)
                                                                   -------------
 Net expenses                                                            58,280
                                                                   -------------
Net investment income (loss)                                            (33,803)
                                                                   -------------
REALIZED AND UNREALIZED GAIN (LOSS)
-----------------------------------
Net realized gain (loss)
 Securities                                                             571,443
 Foreign currency transactions                                           (1,894)
                                                                   -------------
 Net realized gain (loss)                                               569,549
Change in net unrealized gain or loss on securities                    (998,685)
                                                                   -------------
Net realized and unrealized gain (loss)                                (429,136)
                                                                   -------------
INCREASE (DECREASE) IN NET
ASSETS FROM OPERATIONS                                               $ (462,939)
                                                                   -------------

The accompanying notes are an integral part of these financial statements.
================================================================================

<PAGE>

T. Rowe Price Science & Technology Fund
--------------------------------------------------------------------------------
Unaudited
STATEMENT OF CHANGES IN NET ASSETS
----------------------------------
In thousands
                                                        6 Months            Year
                                                           Ended           Ended
                                                         6/30/00        12/31/99
                                                   -------------   -------------
INCREASE (DECREASE) IN NET ASSETS
Operations
 Net investment income (loss)                         $ (33,803)      $ (18,136)
 Net realized gain (loss)                               569,549       2,299,852
 Change in net unrealized gain or loss                 (998,685)      3,341,332
                                                   -------------   -------------
 Increase (decrease) in net assets from operations     (462,939)      5,623,048
                                                   -------------   -------------
Distributions to shareholders
 Net realized gain
  Science & Technology shares                                 -      (1,713,649)
                                                   -------------   -------------
Capital share transactions *
 Shares sold
  Science & Technology shares                         4,380,552       3,840,762
  Science & Technology Advisor Class shares                 517               -
                                                   -------------   -------------
 Increase in net assets from shares sold              4,381,069       3,840,762
 Distributions reinvested
  Science & Technology shares                                 -       1,676,543
 Shares redeemed
  Science & Technology shares                        (2,061,501)     (1,851,625)
                                                   -------------   -------------
 Increase (decrease) in net assets from
 capital share transactions                           2,319,568       3,665,680
                                                   -------------   -------------

<PAGE>

NET ASSETS
----------
Increase (decrease) during period                     1,856,629       7,575,079
Beginning of period                                  12,270,632       4,695,553
                                                   -------------   -------------
END OF PERIOD                                      $ 14,127,261    $ 12,270,632
                                                   -------------   -------------
*Share information
 Shares sold
  Science & Technology shares                            67,481          76,475
  Science & Technology Advisor Class shares                   8               -
 Distributions reinvested
  Science & Technology shares                                 -          29,465
 Shares redeemed
  Science & Technology shares                           (32,198)        (37,992)
                                                   -------------   -------------
 Increase (decrease) in shares outstanding               35,291          67,948

The accompanying notes are an integral part of these financial statements.
================================================================================
T. Rowe Price Science & Technology Fund
--------------------------------------------------------------------------------
Unaudited                                                          June 30, 2000
NOTES TO FINANCIAL STATEMENTS
-----------------------------

NOTE 1 - SIGNIFICANT ACCOUNTING POLICIES

     T. Rowe Price  Science & Technology  Fund,  Inc.  (the fund) is  registered
under the Investment Company Act of 1940 as a diversified,  open-end  management
investment  company.  The fund has two classes of  sharesNScience  & Technology,
offered since September 30, 1987, and Science & Technology  Advisor Class, first
offered on March 31, 2000.  Science & Technology  Advisor Class sells its shares
only through financial intermediaries, which it compensates for distribution and
certain  administrative  services under a  Board-approved  Rule 12b-1 plan. Each
class has  exclusive  voting  rights on matters  related  solely to that  class,
separate voting rights on matters that relate to both classes, and, in all other
respects,  the same rights and  obligations  as the other class.  The fund seeks
long-term  capital  appreciation by investing  primarily in the common stocks of
companies  expected to benefit  from the  development,  advancement,  and use of
science and technology.

     The  accompanying  financial  statements  are prepared in  accordance  with
generally  accepted  accounting  principles for the investment company industry;
these principles may require the use of estimates by fund management.


<PAGE>

     VALUATION  Equity  securities  listed or  regularly  traded on a securities
exchange are valued at the last quoted sales price on the day the valuations are
made.  A security  which is listed or traded on more than one exchange is valued
at the quotation on the exchange  determined  to be the primary  market for such
security.  Listed  securities  not  traded on a  particular  day and  securities
regularly  traded in the  over-the-counter  market are valued at the mean of the
latest  bid and asked  prices.  Other  equity  securities  are valued at a price
within  the limits of the  latest  bid and asked  prices  deemed by the Board of
Directors, or by persons delegated by the Board, best to reflect fair value.

     Investments  in mutual  funds are valued at the closing net asset value per
share of the mutual fund on the day of valuation.

     For purposes of determining the fund's net asset value per share,  the U.S.
dollar  value of all  assets  and  liabilities  initially  expressed  in foreign
currencies  is  determined by using the mean of the bid and offer prices of such
currencies against U.S. dollars quoted by a major bank.


     Assets  and  liabilities  for  which  the above  valuation  procedures  are
inappropriate  or are deemed not to reflect  fair value are stated at fair value
as determined in good faith by or under the  supervision  of the officers of the
fund, as authorized by the Board of Directors.

     AFFILIATED  COMPANIES As defined by the Investment  Company Act of 1940, an
affiliated  company is one in which the fund owns at least 5% of the outstanding
voting securities.

     CURRENCY  TRANSLATION  Assets  and  liabilities  are  translated  into U.S.
dollars at the  prevailing  exchange  rate at the end of the  reporting  period.
Purchases and sales of securities  and income and expenses are  translated  into
U.S. dollars at the prevailing  exchange rate on the dates of such transactions.
The effect of  changes in foreign  exchange  rates on  realized  and  unrealized
security gains and lo sses is reflected as a component of such gains and losses.

     CLASS ACCOUNTING The Science & Technology  Advisor Class pays  distribution
and  administrative  expenses,  in the form of Rule 12b-1 fees, in an amount not
exceeding  0.25% of the  class's  average  net  assets.  Shareholder  servicing,
prospectus, and shareholder report expenses are charged directly to the class to
which they relate.  Expenses  common to both  classes,  investment  income,  and
realized and unrealized gains and losses are allocated to the classes based upon
the relative daily net assets of each class.  Income  distributions are declared
and paid by each class on an annual basis.

     OTHER Income and expenses  are  recorded on the accrual  basis.  Investment
transactions are accounted for on the trade date.  Realized gains and losses are
reported on the identified  cost basis.  Dividend  income and  distributions  to
shareholders  are  recorded  by the fund on the  ex-dividend  date.  Income  and
capital gain  distributions are determined in accordance with federal income tax
regulations  and may differ from those  determined in accordance  with generally
accepted accounting principles.  Expenses paid indirectly reflect credits earned
on daily  uninvested  cash  balances at the custodian and are used to reduce the
fund's custody charges.


<PAGE>

NOTE 2 - INVESTMENT TRANSACTIONS

     Purchases  and  sales  of  portfolio  securities,   other  than  short-term
securities, aggregated $10,509,737,000 and $8,112,990,000, respectively, for the
six months ended June 30, 2000.

NOTE 3 - FEDERAL INCOME TAXES

     No provision for federal income taxes is required since the fund intends to
continue to qualify as a regulated  investment company and distribute all of its
taxable income.

     At June 30, 2000, the cost of  investments  for federal income tax purposes
was   substantially   the  same  as  for   financial   reporting   and   totaled
$10,269,957,000. Net unrealized gain aggregated $3,917,128,000 at period-end, of
which  $4,728,968,000  related to appreciated  investments  and  $811,840,000 to
depreciated investments.

NOTE 4 - FOREIGN TAXES

     The fund is subject to foreign income taxes imposed by certain countries in
which it invests. Foreign income taxes are accrued by the fund and withheld from
dividend and interest income.

NOTE 5 - RELATED PARTY TRANSACTIONS

     The  investment  management  agreement  between  the fund and T. Rowe Price
Associates, Inc. (the manager) provides for an annual investment management fee,
of which  $7,825,000 was payable at June 30, 2000. The fee is computed daily and
paid monthly,  and consists of an individual  fund fee equal to 0.35% of average
daily net assets and a group fee. The group fee is based on the combined  assets
of  certain  mutual  funds  sponsored  by  the  manager  or  Rowe  Price-Fleming
International,  Inc.  (the group).  The group fee rate ranges from 0.48% for the
first $1 billion of assets to 0.295%  for assets in excess of $120  billion.  At
June 30, 2000, and for the six months then ended, the effective annual group fee
rate was  0.32%.  The fund pays a  pro-rata  share of the group fee based on the
ratio of its net assets to those of the group.

     The manager has agreed to bear any  expenses  through  December  31,  2001,
which would cause Science & Technology  Advisor  Class's ratio of total expenses
to average net assets to exceed 1.15%.  Thereafter,  through  December 31, 2003,
Science &  Technology  Advisor  Class is required to  reimburse  the manager for
these expenses, provided that its average net assets have grown or expenses have
declined  sufficiently to allow reimbursement without causing its ratio of total
expenses to average net assets to exceed 1.15%.


<PAGE>

     In addition,  the fund has entered into agreements with the manager and two
wholly owned  subsidiaries  of the manager,  pursuant to which the fund receives
certain other services. The manager computes the daily share price and maintains
the financial  records of the fund. T. Rowe Price  Services,  Inc. is the fund's
transfer  and  dividend   disbursing   agent  and   provides   shareholder   and
administrative  services to the fund. T. Rowe Price  Retirement  Plan  Services,
Inc. provides  subaccounting and recordkeeping  services for certain  retirement
accounts  invested in the fund.  The fund  incurred  expenses  pursuant to these
related party agreements  totaling  approximately  $9,035,000 for the six months
ended June 30, 2000, of which $1,654,000 was payable at period-end.

     The fund may invest in the Reserve  Investment Fund and Government  Reserve
Investment  Fund   (collectively,   the  Reserve  Funds),   open-end  management
investment companies managed by T. Rowe Price Associates, Inc. The Reserve Funds
are offered as cash  management  options only to mutual funds and other accounts
managed by T. Rowe Price and its affiliates and are not available to the public.
The Reserve  Funds pay no investment  management  fees.  Distributions  from the
Reserve  Funds to the fund  for the six  months  ended  June 30,  2000,  totaled
$14,328,000 and are reflected as interest income in the  accompanying  Statement
of Operations.
================================================================================
T. Rowe Price Shareholder Services
--------------------------------------------------------------------------------
INVESTMENT SERVICES AND INFORMATION

KNOWLEDGEABLE SERVICE REPRESENTATIVES
-------------------------------------
BY PHONE 1-800-225-5132 Available Monday through Friday from
8 a.m. to 10 p.m. ET and weekends from 8:30 a.m. to 5 p.m. ET.

IN PERSON Available in T. Rowe Price Investor Centers.

ACCOUNT SERVICES
----------------
CHECKING Available on most fixed-income funds ($500 minimum).

AUTOMATIC INVESTING From your bank account or paycheck.

AUTOMATIC WITHDRAWAL Scheduled, automatic redemptions.

DISTRIBUTION OPTIONS Reinvest all, some, or none of your distributions.

AUTOMATED 24-HOUR SERVICES Including Tele*AccessRegistration Mark and the
T. Rowe Price Web site on the Internet. Address: www.troweprice.com

BROKERAGE SERVICES*
-------------------
Individual Investments Stocks, bonds, options, precious metals,
and other securities at a savings over full-service commission rates. **


<PAGE>

INVESTMENT INFORMATION
----------------------
COMBINED STATEMENT Overview of all your accounts with T. Rowe Price.

SHAREHOLDER REPORTS Fund managers' reviews of their strategies and results.

T. ROWE PRICE REPORT Quarterly investment newsletter discussing
markets and financial strategies.

PERFORMANCE UPDATE Quarterly review of all T. Rowe Price fund results.

INSIGHTS Educational reports on investment strategies and financial markets.

INVESTMENT GUIDES Asset Mix Worksheet, College Planning Kit,
Diversifying Overseas: A Guide to International Investing, Personal
Strategy Planner, Retirees Financial Guide, and Retirement Planning Kit.

     *    T. Rowe  Price  Brokerage  is a division  of T. Rowe Price  Investment
          Services, Inc., Member NASD/SIPC.

     **   Based on a  September  1999 survey for  representative-assisted  stock
          trades.  Services vary by firm, and  commissions may vary depending on
          size of order.

================================================================================
FOR FUND AND ACCOUNT INFORMATION
OR TO CONDUCT TRANSACTIONS,
24 HOURS, 7 DAYS A WEEK
By touch-tone telephone
TELE*ACCESS 1-800-638-2587
By Account Access on the Internet
WWW.TROWEPRICE.COM/ACCESS

FOR ASSISTANCE
WITH YOUR EXISTING
FUND ACCOUNT, CALL:
Shareholder Service Center
1-800-225-5132

TO OPEN A BROKERAGE ACCOUNT
OR OBTAIN INFORMATION, CALL:
1-800-638-5660

INTERNET ADDRESS:
www.troweprice.com

PLAN ACCOUNT LINES FOR RETIREMENT
PLAN PARTICIPANTS:
The appropriate 800 number appears
on your retirement account statement.


<PAGE>

T. Rowe Price Associates
100 East Pratt Street
Baltimore, Maryland 21202

This report is authorized for
distribution only to shareholders
and to others who have received
a copy of the prospectus appropriate
to the fund or funds covered in this
report.

WALK-IN INVESTOR CENTERS:
For directions,  call 1-800-225-5132
or visit our Web site

BALTIMORE  AREA
DOWNTOWN
101 East  Lombard  Street
OWINGS  MILLS
Three Financial  Center
4515  Painters  Mill Road

BOSTON  AREA
386  Washington  Street
Wellesley

COLORADO SPRINGS
4410 ArrowsWest Drive

LOS ANGELES AREA
Warner Center
21800 Oxnard  Street,  Suite 270
Woodland  Hills

TAMPA
4200 West Cypress  Street
10th Floor

WASHINGTON, D.C.
900 17th Street N.W.
Farragut Square

T. Rowe Price Investment Services, Inc., Distributor.         F61-051  6/30/00


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