BENTLEY PHARMACEUTICALS INC
S-3, 1997-06-06
PHARMACEUTICAL PREPARATIONS
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      As filed with the Securities and Exchange Commission on June 6, 1997
                                                 Registration No. 333-_________
- --------------------------------------------------------------------------------
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                        --------------------------------
                                    FORM S-3
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933
                        --------------------------------
                          BENTLEY PHARMACEUTICALS, INC.
             (Exact Name of Registrant as Specified in its Charter)
<TABLE>
<S>                                                                                            <C>       
           Florida                                                                             59-1513162
(State or Other Jurisdiction                                                              (I.R.S. Employer
      of Incorporation                                                                     Identification No.)
       or Organization)
                                                                                       Mr. James R. Murphy
                                                                                      Bentley Pharmaceuticals, Inc.
                        One Urban Centre                                                    One Urban Centre
                            Suite 548                                                           Suite 548
                     4830 West Kennedy Blvd.                                             4830 West Kennedy Blvd.
                      Tampa, Florida  33609                                               Tampa, Florida  33609
                         (813) 286-4401                                                      (813) 286-4401
       (Address, Including Zip Code, and Telephone Number               (Name, Address, Including Zip Code, and Telephone Number,
Including Area Code, of Registrant's Principal Executive Offices)              Including Area Code, of Agent For Service)
                          ----------------------------
                                    Copy to:

                              Mark S. Hirsch, Esq.
                             Jordan A. Horvath, Esq.
                       Parker Chapin Flattau & Klimpl, LLP
                           1211 Avenue of the Americas
                            New York, New York 10036
                          -----------------------------
     Approximate date of commencement of proposed sale to the public:  From time
to time after this Registration  Statement becomes  effective,  as determined by
market conditions.
     If the only  securities  being  registered  on this form are being  offered
pursuant to dividend or interest  reinvestment plans, please check the following
box.
     If any of the securities being registered on this form are to be offered on
a delayed or continuous  basis  pursuant to Rule 415 under the Securities Act of
1933, other than securities offered only in connection with dividend or interest
reinvestment plans, check the following box. X
     If this Form is filed to  register  additional  securities  for an offering
pursuant to Rule 462(b) under the Securities Act, please check the following box
and list  the  Securities  Act  registration  statement  number  of the  earlier
effective registration statement for the same offering. _____________________
     If this Form is a  post-effective  amendment  filed pursuant to rule 462(c)
under the  Securities  Act,  check the following box and list the Securities Act
registration  statement number of the earlier effective  registration  statement
for the same offering.
     If delivery of the  prospectus is expected to be made pursuant to Rule 434,
please check the following box.

                         CALCULATION OF REGISTRATION FEE
============================================================================================================
                                                      Proposed             Proposed
                                                      Maximum               Maximum          Amount Of
     Title of Shares              Amount To       Aggregate Price          Aggregate       Registration
     To Be Registered           Be Registered      Per Share (1)      Offering Price (1)        Fee
- ------------------------------------------------------------------------------------------------------------
Common Stock, $.02 par value    2,103,150 shares       $3.4063           $7,163,854.70        $2,171
per share
============================================================================================================

(1)  Estimated  solely  for the  purpose of  calculating  the  registration  fee
     pursuant  to Rule 457,  based on the  average of the high and low  reported
     sales prices on the American Stock Exchange on June 3, 1997.

     The Registrant  hereby amends this  Registration  Statement on such date or
dates as may be necessary to delay its effective date until the Registrant shall
file a further  amendment  which  specifically  states  that  this  Registration
Statement shall  thereafter  become effective in accordance with Section 8(a) of
the Securities  Act of 1933 or until this  Registration  Statement  shall become
effective on such date as the  Commission,  acting pursuant to Section 8(a), may
determine.
- --------------------------------------------------------------------------------
</TABLE>

<PAGE>



                    Subject to Completion, Dated June 6, 1997

                                   PROSPECTUS

- --------------------------------------------------------------------------------

                                2,103,150 Shares

                          BENTLEY PHARMACEUTICALS, INC.

                                  Common Stock

- --------------------------------------------------------------------------------


            This Prospectus  relates to up to 2,103,150 shares (the "Shares") of
Common  Stock,  par value  $.02 per  share  (the  "Common  Stock"),  of  Bentley
Pharmaceuticals,  Inc.  (the  "Company").  The  Shares may be offered by certain
stockholders of the Company (the "Selling  Stockholders") in transactions on the
American Stock Exchange, the Pacific Exchange, Inc., in negotiated transactions,
or in a  combination  of such  methods  of sale,  at fixed  prices  which may be
changed,  at market prices  prevailing at the time of sale, at prices related to
such prevailing market prices or at negotiated prices. The Selling  Stockholders
may  effect   such   transactions   to  or  through   broker-dealers   and  such
broker-dealers may receive compensation in the form of discounts, concessions or
commissions  from  the  Selling  Stockholders  and/or  the  purchasers  of  such
securities  for whom  such  broker-dealers  may act as agent or to whom they may
sell  as  principals,   or  both  (see  "Plan  of  Distribution"   and  "Selling
Stockholders"  below). The Company will not receive any of the proceeds from the
sale of the Shares (see "Use of Proceeds,"  "Selling  Stockholders" and "Plan of
Distribution"  below). The Company has agreed to bear all expenses in connection
with the registration of the Shares.

            The Company's  Common Stock is traded on the American Stock Exchange
and the Pacific  Exchange,  Inc. under the symbol "BNT".  The last reported sale
price of the Company's  Common Stock on the American  Stock  Exchange on June 3,
1997 was $3.375 per share.  The Company's  executive  offices are located at One
Urban Centre, Suite 548, 4830 West Kennedy Boule vard, Tampa, Florida 33609, and
its telephone number is (813) 286-4401.

                      ------------------------------------


         THE SECURITIES OFFERED HEREBY INVOLVE A HIGH DEGREE OF RISK AND
              PROSPECTIVE PURCHASERS SHOULD CAREFULLY CONSIDER THE
               FACTORS SPECIFIED UNDER THE CAPTION "RISK FACTORS"
                      LOCATED ON PAGE 6 OF THIS PROSPECTUS.

                      ------------------------------------


            THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY
               THE SECURITIES AND EXCHANGE COMMISSION OR ANY STATE
               SECURITIES COMMISSION NOR HAS THE COMMISSION OR ANY
                   STATE SECURITIES COMMISSION PASSED UPON THE
                    ACCURACY OR ADEQUACY OF THIS PROSPECTUS.
                     ANY REPRESENTATION TO THE CONTRARY IS A
                                CRIMINAL OFFENSE.

                      ------------------------------------


                  The date of this Prospectus is June __, 1997.

                                       -2-

<PAGE>



                              AVAILABLE INFORMATION

            The  Company  is subject to the  informational  requirements  of the
Securities Exchange Act of 1934, as amended (the "1934 Act"), and, in accordance
therewith,  files  reports,  proxy  statements  and other  information  with the
Securities  and Exchange  Commission  (the  "Commission").  Such reports,  proxy
statements  and other  information  filed by the  Company can be  inspected  and
copied at the public  reference  facilities  maintained by the Commission at 450
Fifth Street,  N.W.,  Washington,  D.C.  20549,  and at the  following  Regional
Offices of the Commission: New York Regional Office, 7 World Trade Center, Suite
1300, New York, New York 10048; and Chicago  Regional  Office,  500 West Madison
Street,  Suite 1400,  Chicago,  Illinois  60661.  Copies of such material may be
obtained  from the  Public  Reference  Section  of the  Commission  at 450 Fifth
Street, N.W.,  Washington,  D.C. 20549, at prescribed rates. Such reports, proxy
statements  and other  information  can also be  inspected at the offices of the
American Stock  Exchange,  86 Trinity Place,  New York, New York 10006, on which
the Company's Common Stock is listed.

            This  Prospectus  does not contain all the  information set forth in
the  Form  S-3  Registration   Statement   (No.333-_____)   (the   "Registration
Statement")  of which this  Prospectus is a part,  including  exhibits  relating
thereto, which has been filed with the Commission in Washington,  D.C. Copies of
the  Registration  Statement  and the  exhibits  thereto may be  obtained,  upon
payment of the fee  prescribed  by the  Commission,  or may be examined  without
charge, at the office of the Commission.  This  Registration  Statement has been
filed  electronically  through  the  Electronic  Data  Gathering,  Analysis  and
Retrieval System (EDGAR) and is publicly  available through the Commission's web
site (http://www.sec.gov).

                 INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

            The  Company's  Annual Report on Form 10-K for the fiscal year ended
December 31, 1996; the Company's  Proxy Statement for the 1997 Annual Meeting of
Stockholders;  the Company's Quarterly Report on Form 10-Q for the quarter ended
March 31, 1997; the  description of the Company's  Common Stock contained in the
Company's  Registration  Statement  on Form 8-A filed on July 20,  1990,  all as
filed pursuant to the 1934 Act,  including any amendment or report filed for the
purpose of updating such descriptions, are hereby incorporated by reference.

            Each  document  filed  subsequent  to the  date of  this  Prospectus
pursuant  to  Section  13(a),  13(c),  14 or 15(d) of the 1934 Act  prior to the
termination of this offering shall be deemed to be  incorporated by reference in
this  Prospectus  and to be a part  hereof  from the date of the  filing of such
documents.  Any statement  contained in a document  incorporated or deemed to be
incorporated  herein by reference  shall be deemed to be modified or  superseded
for purposes of this Prospectus to the extent that a statement  contained herein
or in any other  subsequently  filed  document  which also is or is deemed to be
incorporated by reference herein modifies or supersedes such statement.



                                       -3-

<PAGE>



            The Company will provide  without  charge to each person,  including
any beneficial  owner, to whom a copy of this Prospectus is delivered,  upon the
written or oral request of any such person, a copy of any document  incorporated
by reference in this  Prospectus  (other than exhibits  unless such exhibits are
expressly  incorporated  by reference  in such  documents).  Requests  should be
directed to Bentley  Pharmaceuticals,  Inc.,  One Urban Centre,  Suite 548, 4830
West Kennedy Boulevard, Tampa, Florida 33609, (813) 286-4401, Attention: Michael
D. Price, Chief Financial Officer.


                                       -4-

<PAGE>



                               PROSPECTUS SUMMARY


            The  following  summary is  qualified  in its  entirety  by the more
detailed information appearing elsewhere in this Prospectus.

                                    The Offering

Common Stock Offered by Selling Stockholders............     2,103,150 shares

Common Stock Outstanding Prior to the Offering..........     3,378,186 shares

Common Stock to be Outstanding After
  the Offering (1)......................................     5,444,936 shares

American Stock Exchange Symbol of
  the Common Stock......................................     BNT


- -------------------
(1)    Excludes (i) an aggregate of 14,193,000  shares of Common Stock  reserved
       for issuance upon  conversion or exercise of the  securities  issuable in
       the Company's 1996 public offering (the "Public Offering")  consisting of
       2,760,000 shares issuable upon conversion of the debentures issued in the
       Public  Offering  (the  "Debentures"),  228,000  shares of  Common  Stock
       reserved for issuance upon  conversion of the Debentures  included in the
       units  which  were  issued in the  Public  Offering  (the  "Units")  upon
       exercise of the underwriter  warrants (the "Underwriter  Warrants") which
       were  issued in the Public  Offering,  6,900,000  shares of Common  Stock
       issuable  upon the exercise of the Class A Warrants  issued in the Public
       Offering,  3,450,000 shares of Common Stock issuable upon the exercise of
       the Class B Warrants which may be issued  pursuant to the exercise of the
       Class A Warrants issued in the Public Offering,  570,000 shares of Common
       Stock  issuable  upon  exercise  of the Class A Warrants  included in the
       Units issuable upon the exercise of the Underwriter  Warrants and 285,000
       shares of Common  Stock  issuable  upon  exercise of the Class B Warrants
       issuable upon the exercise of the Class A Warrants  which are included in
       the Units issuable  pursuant to the  Underwriter  Warrants;  (ii) 318,847
       shares of Common Stock reserved for issuance upon exercise of outstanding
       stock  purchase  warrants which were issued in various  transactions  not
       related to the  Public  Offering;  (iii)  57,100  shares of Common  Stock
       reserved for issuance upon exercise of stock options;  (iv) 14,960 shares
       of Common Stock  reserved for issuance  upon  conversion  of the Series A
       Preferred Stock or upon conversion of 9% Convertible  Debentures due 2016
       into which the Series A Preferred  Stock is  exchangeable;  and (v) 2,183
       shares of Common Stock  reserved  for issuance to current  members of the
       Board of Directors of the Company as compensation.




                                       -5-

<PAGE>



                                  RISK FACTORS

     The  securities  offered hereby are  speculative  and involve a substantial
degree of risk.  Prospective  investors  should give careful  consideration  to,
among other items, the following factors prior to making an investment decision.

     Certain  statements  in  this  Prospectus  that  are not  historical  facts
constitute  "forward-looking  statements"  within  the  meaning  of the  Private
Securities  Litigation  Reform  Act of  1995.  Such  forward-looking  statements
involve known and unknown risks, uncertainties and other factors which may cause
the actual results of the Company to be materially different from the historical
results  or from any  results,  expressed  or  implied  by such  forward-looking
statements.  Such risks,  uncertainties  and other factors include,  but are not
limited to, the following risks.

Financial Risks

     History of Operating  Losses;  Accumulated  Deficit;  Uncertainty of Future
Financial Results. As of March 31, 1997, the Company had a cumulative deficit of
approximately  $67,993,000.  The Company has realized  significant losses in the
past and could have  quarterly and annual losses in the future.  The Company has
not generated any profits from  operations.  The Company has realized quarter to
quarter  fluctuations in its results in the past and, although such fluctuations
have been minimal in recent  quarters,  they may be  significant  in the future.
Consequently,  the Company may continue to operate at a loss for the foreseeable
future and there can be no assurance that the Company's business will operate on
a profitable basis.

     Negative Cash Flow From Operating  Activities.  The Company is experiencing
negative  cash  flow  from  operations  resulting  in the  need to fund  ongoing
operations from financing activities.  In October 1995 the Company completed two
private  placements  resulting in net  proceeds to the Company of  approximately
$1,590,000,  all of which was used for  working  capital  purposes.  The  Public
Offering  resulted in proceeds to the  Company of  approximately  $5,700,000.  A
substantial  portion of the  proceeds  of the Public  Offering  has been used to
repay the debt  incurred in the private  placements.  The future  existence  and
profitability of the Company is dependent upon its ability to obtain  additional
funds to  finance  operations  and  expand  operations  in an effort to  achieve
profitability  from  operations.  No assurance  can be given that the  Company's
business  will  ultimately  generate  sufficient  revenue to fund the  Company's
operations on a continuing basis.

     Limited  Revenues.  Although  the Company was founded in 1974,  it has only
generated revenue from product-related  sales since August 1991. The Company has
used cash from financing activities to fund its operations. The Company has made
progress  toward  commercialization  of  specific  products  and  has  commenced
commercialization  of others. The Company is now generating  revenues from sales
of products of its  subsidiaries,  Laboratorios  Belmac,  S.A., a pharmaceutical
manufacturer  located in Spain ("Laboratorios  Belmac") and Chimos/LBF,  S.A., a
company based in France which distributes specialty  pharmaceutical products and
chemicals in France ("Chimos").  Chimos and Laboratorios Belmac were acquired by
the Company in August 1991 and February 1992, respectively. See "Negotiations to
Sell Chimos." Substantial amounts of time and financial and other resources will
be required to complete the  development  and clinical  testing of the Company's
products

                                       -6-

<PAGE>



currently under development.  Due to its limited cash resources, the Company has
suspended most of its research and development  activities pending the selection
of strategic partners for development and marketing.  There is no assurance that
the Company will receive  additional  funding necessary to continue research and
development  activities  or that it will  otherwise  succeed in  developing  any
additional products with commercially valuable applications.

     Additional Financing  Requirements.  The Company believes that its emphasis
on product  distribution  in France and Spain,  strategic  alliances and product
acquisitions  together with careful  management of its research and  development
activities  and the net  proceeds  from  the  Public  Offering,  should  provide
sufficient  liquidity to enable it to conduct its existing operations into 1998,
of which  there  can be no  assurance.  However,  the  Company's  pharmaceutical
products being  developed and which may be developed will require the investment
of substantial additional time as well as financial and other resources in order
to  become  commercially  successful.  Following  the  development  period,  the
Company's products will generally be required to go through lengthy governmental
approval  processes,  including  extensive clinical testing,  followed by market
development.  The  Company's  operating  revenues and cash  resources may not be
sufficient  over the next several years for the  commercialization  by itself of
any of the products  currently  in  development.  Consequently,  the Company may
require additional licensees or partners and/or additional financing.  There can
be no  assurance,  however,  that  the  Company  can  conclude  such  commercial
arrangements or obtain additional capital when needed on acceptable terms, if at
all.

     Possible  Restriction  on  Ability  to  Utilize  Net  Operating  Loss Carry
Forwards  Resulting  from Change in Equity  Ownership and Change in Tax Year. At
December 31, 1996, the Company has net operating loss (the "NOLs") carryforwards
of approximately $38,000,000 available to offset future U.S. taxable income. The
Company  calculates  that its use of the NOLs will be limited  to  approximately
$3,000,000 each year as a result of stock,  option and warrant  issuances during
prior fiscal years which resulted in an ownership change of more than 50% of the
Company's outstanding equity. Additionally, approximately $1,800,000 of the NOLs
generated in 1995 available to offset future U.S. taxable income will be limited
to approximately  $300,000 per year over the next six years due to the change in
tax year end during 1995. If not offset against future taxable  income,  the NOL
carryforwards  will  expire  in tax  years  1997  through  2011.  The  Company's
subsidiaries  in France  and  Spain  have NOL carry  forwards  of  approximately
$13,300,000  and  $2,700,000,  respectively.  These will expire in various years
ending in 2001.

Business Risks

     No Assurance of Successful and Timely Development of New Products. Although
the Company has a limited number of products in various  stages of  development,
including  pre-clinical  testing and  clinical  trials,  the Company has not yet
substantially marketed any of these products other than Biolid(R) (the Company's
macrolide  antibiotic)  in  France,  the  marketing  of  which  has  since  been
suspended.  During a  periodic  review of the  dossier  of  Biolid  by  France's
Ministry  of Health in 1993 which was  completed  shortly  after the Company had
negotiated the sale of its rights to the sachet formulation of Biolid in France,
the Ministry required the suspension of marketing of Biolid pending provision by
the  Company of  additional  clinical  data  regarding  the  mechanisms  for the
comparatively  enhanced  absorption of the Biolid  sachet.  The  suspension  was
unrelated to safety or efficacy issues,

                                       -7-

<PAGE>



but has not been lifted  since the Company has not had  sufficient  resources to
conduct the study required.  See "Risks Inherent in Pharmaceutical  Development;
Dependency on Regulatory  Approvals"  below.  There can be no assurance that the
Company will be able to develop large scale production of any particular product
for clinical trials or eventual commercial production.  The marketing of certain
of the Company's  products  could be adversely  affected by delays in developing
large-scale production processes,  developing or acquiring production facilities
or obtaining regulatory approval for such processes or facilities.

     Risks  Inherent in  Pharmaceutical  Development;  Dependence  on Regulatory
Approvals. The process of creating, scaling-up,  manufacturing and marketing any
new human pharmaceutical  product is inherently risky. There can be no assurance
that  any  drug  under  development  will  be  safe  and  effective.   Moreover,
pharmaceutical  products  are  subject  to  significant  regulation.  Any  human
pharmaceutical  product  developed  by the Company  would  require  clearance by
Spain's Ministry of Health for sales in Spain,  France's  Ministry of Health for
sales in France, the U.S. Food and Drug Administration  ("FDA") for sales in the
United States and similar agencies in other countries.  The process of obtaining
these approvals is costly and time-consuming, and there can be no assurance that
such  approvals  will be granted.  In general,  only a small  percentage  of new
pharmaceutical products achieve commercial success. Such governmental regulation
may prevent or substantially  delay the marketing of the Company's  products and
may cause the  Company  to  undertake  costly  procedures  with  respect  to its
research and development  and clinical  testing  operations  which may furnish a
competitive advantage to more substantially  capitalized companies which compete
with the Company. In addition,  the Company is required,  in connection with its
activities,  to comply with good manufacturing practices (GMPs) and local, state
and federal  regulations.  Non-compliance  with these  regulations  could have a
material adverse effect on the Company and/or prevent the  commercialization  of
the Company's products.

     Dependency on Others;  Discontinuation of Certain Marketing Activities. The
Company  relies on outside  contractors  for  manufacturing  of the  products it
distributes  in  France.  Until  the  distribution   agreement  between  Genzyme
Corporation and Chimos expired on March 31, 1996, the Company relied on sales of
Ceredase,  a drug used in the treatment of Gaucher's  Disease and other products
by Chimos to Pharmacie  Centrale des Hopitaux.  Sales to Pharmacie  Centrale des
Hopitaux accounted for approximately 10%, 23% and 30% of the Company's sales for
the years ended December 31, 1996,  1995 and 1994,  respectively.  Consequently,
the Company's  sales in France  declined  significantly  beginning in the second
quarter of 1996 as a result of the  expiration  of the  distribution  agreement.
Notwithstanding  the relative  significance  of its sales  volume,  the Ceredase
gross  margins as a percentage  of sales were  minimal,  therefore the impact on
operating  profits was not material.  The Company is exploring  alternative uses
for  its  working   capital  that  has   historically   supported  the  Ceredase
distribution  arrangement.  Chimos,  as one of the  authorized  distributors  of
Orphan  Drugs in France,  is  occasionally  contacted by  manufacturers  of such
products outside of France to act as their distributor. In addition, the Company
from time to time  supplies  Chimos with a list of Orphan Drugs  approved by the
FDA in the  United  States  and  Chimos  contacts  their  manufacturers  to seek
becoming their distributor in France. See "Negotiations to Sell Chimos."

     Negotiations  to  Sell  Chimos.   The  Company  is  currently   engaged  in
negotiations with a subsidiary of a large European  conglomerate to sell Chimos.
The transaction is expected to be

                                       -8-

<PAGE>



finalized in the second  quarter of 1997.  As no  definitive  agreement has been
signed, there can be no assurance that such sale will be consummated.  Since the
expiration of the Ceredase  distribution  agreement,  Chimos has been generating
revenues at the rate of approximately $5.5 million per annum. See "Dependency on
Others; Discontinuation of Certain Marketing Activities."

     Uncertainty of Pharmaceutical  Pricing,  Profitability and Related Matters.
The levels of revenues and  profitability  of  pharmaceutical  companies  may be
affected by the  continuing  efforts of  governmental  and third party payers to
contain or reduce the costs of health care through  various means.  For example,
in certain foreign markets, including Spain and France, pricing or profitability
of prescription  pharmaceuticals is subject to government control. In the United
States, there have been, and the Company expects that there will continue to be,
a number of federal and state proposals to implement similar government control.
While the Company  cannot  predict  whether any such  legislative  or regulatory
proposals will be adopted,  the adoption of such proposals could have a material
adverse effect on the Company's business, financial condition and profitability.
In addition, sales of prescription  pharmaceuticals are dependent in part on the
availability of reimbursement  to the consumer from third party payers,  such as
government  and private  insurance  plans.  Third party payers are  increasingly
challenging the prices charged for medical products and services. If the Company
succeeds  in  bringing  one or more  products  to the  market,  there  can be no
assurance  that  these  products  will be  considered  cost  effective  and that
reimbursement  to the consumer  will be available or will be sufficient to allow
the Company to sell its products on a competitive basis.

     Unpredictability of Patent Protection;  Proprietary Technology. The Company
has filed numerous patent applications and has been granted a number of patents.
However,  there can be no assurance that its pending applications will be issued
as patents or that any of its issued patents will afford adequate  protection to
the Company or its licensees.  Other private and public entities have also filed
applications  for,  or have been  issued,  patents  and are  expected  to obtain
patents and other  proprietary  rights to technology which may be harmful to the
commercialization of the Company's products.  The ultimate scope and validity of
patents which are now owned by or may be granted to third parties in the future,
the extent to which the Company may wish or be required to acquire  rights under
such patents,  and the cost or  availability of such rights cannot be determined
by the Company at this time. In addition,  the Company also relies on unpatented
proprietary technology in the development and commercialization of its products.
There is no  assurance  that  others may not  independently  develop the same or
similar technology or obtain access to the Company's proprietary technology.

     The Company also relies upon trade secrets, unpatented proprietary know-how
and continuing  technological  innovations to develop its competitive  position.
All of  the  Company's  employees  with  access  to  the  Company's  proprietary
information  have entered  into  confidentiality  agreements  and have agreed to
assign to the Company any inventions  relating to the Company's business made by
them while in the  Company's  employ.  However,  there can be no assurance  that
others may not  acquire  or  independently  develop  similar  technology  or, if
patents in all major  countries  are not issued  with  respect to the  Company's
products,  that the Company  will be able to maintain  information  pertinent to
such research as proprietary technology or trade secrets.


                                       -9-

<PAGE>



     Rapid Technological Change. The pharmaceutical industry has undergone rapid
and  significant  technological  change.  The Company  expects the technology to
continue to develop rapidly, and the Company's success will depend significantly
on its  ability to maintain a  competitive  position.  The Company has  recently
shifted its strategic focus so that it does not rely on research and development
of pharmaceuticals from concept through marketing.  Instead, it seeks to acquire
late-stage  development  compounds that can be marketed within approximately one
year and currently-marketed products. Rapid technological development may result
in actual and  proposed  products  or  processes  becoming  obsolete  before the
Company  recoups a  significant  portion of related  research  and  development,
acquisition and commercialization costs.

     Competition.  The  Company  is in  competition  with  other  pharmaceutical
companies,  biotechnology  firms  and  chemical  companies,  many of which  have
substantially greater financial, marketing and human resources than those of the
Company (including, in some cases,  substantially greater experience in clinical
testing,  production and marketing of pharmaceutical products). The Company also
experiences  competition  in the  development of its products and processes from
individual scientists,  hospitals,  universities and other research institutions
and, in some instances,  competes with others in acquiring technology from these
sources.

     Uncertainty  of Orphan  Drug  Designation.  An Orphan  Drug is a product or
products  used to treat a rare disease or  condition,  which,  as defined  under
United States law, is a disease or condition  that affects  populations  of less
than 200,000  individuals  or, if victims of a disease number more than 200,000,
the sponsor  establishes that it does not  realistically  anticipate its product
sales will be  sufficient  to recover its costs.  If a product is  designated an
Orphan  Drug,  then the  sponsor is entitled to receive  certain  incentives  to
undertake the development and marketing of the product.  In Spain,  Orphan Drugs
are given a preference in the pharmaceutical  review process by Spain's Ministry
of Health if it can be shown that the product is an important  therapeutic agent
and there is unequivocal  data  supporting its efficacy.  The Ministry of Health
has the authority to require pharmaceutical manufacturers to continue to produce
products which are Orphan Drugs  regardless of their  commercial  potential.  As
required by the Ministry of Health,  Laboratorios Belmac currently  manufactures
and  distributes one Orphan Drug,  Anacalcit,  which is used in the treatment of
nephrolithiasis.  In France,  Orphan Drug status is granted by France's Ministry
of Health.  Chimos does not currently own in its portfolio any Orphan Drugs, but
does act as a  distributor  for other  companies  who have Orphan Drug status in
France.  The Company  does not  currently  market any Orphan Drugs in the United
States.

     Attraction and Retention of Key Personnel. The Company believes that it has
been  able  to  attract  skilled  and  experienced   management  and  scientific
personnel. There can be no assurance, however, that the Company will continue to
attract and retain personnel of high caliber.  Since 1992, five individuals have
served  as the  Company's  chief  executive  officer.  This  instability  in the
Company's  management in the past has hampered the Company's  growth.  While the
Company believes that it has assembled an effective management team, the loss of
several individuals who are considered key management or scientific personnel of
the  Company  could  have  an  adverse  impact  on  the  Company.  Although  all
discoveries  and research of each  employee  made during  employment  remain the
property  of the  Company,  the  Company  has not  entered  into  noncompetition
agreements  with its key employees and such employees would therefore be able to
leave and compete with the Company.

                                      -10-

<PAGE>



     Risk of Product  Liability.  The Company faces an inherent business risk of
exposure to product liability claims in the event that the use of its technology
or prospective  products is alleged to have resulted in adverse  effects.  While
the  Company  has  taken,  and will  continue  to  take,  what it  believes  are
appropriate  precautions,   there  can  be  no  assurance  that  it  will  avoid
significant   liability  exposure.   The  Company  maintains  product  liability
insurance in the amount of $5 million.  However, there is no assurance that this
coverage will be adequate in terms and scope to protect the Company in the event
of a product liability claim. In connection with the Company's  clinical testing
activities,  the Company may, in the ordinary course of business,  be subject to
substantial  claims  by, and  liability  to,  subjects  who  participate  in its
studies.

     Risk of  Doing  Business  Outside  the  United  States.  Nearly  all of the
Company's  revenues during 1995 and 1996 have been generated  outside the United
States, from the Company's  subsidiaries in France and Spain. There are risks in
operation outside the United States, including,  among others, the difficulty of
administering  businesses abroad,  exposure to foreign currency fluctuations and
devaluations or restrictions on money supplies,  foreign and domestic export law
and  regulations,  taxation,  tariffs,  import quotas and restrictions and other
political and economic events beyond the Company's control.  The Company has not
experienced any material  effects of these risks as of yet, however there can be
no assurance that they will not have such an effect in the future.

     Certain Florida  Legislation.  The State of Florida has enacted legislation
that may deter or  frustrate  takeovers  of Florida  corporations.  The  Florida
Control Share Act generally  provides that shares  acquired in excess of certain
specified  thresholds  will not  possess  any voting  rights  unless such voting
rights  are  approved  by  a  majority  vote  of a  corporation's  disinterested
stockholders.   The  Florida  Affiliated  Transactions  Act  generally  requires
supermajority  approval  by  disinterested  stockholders  of  certain  specified
transactions  between a public  corporation  and holders of more than 10% of the
outstanding voting shares of the corporation (or their affiliates).  Florida law
also  authorizes  the Company to indemnify  the Company's  directors,  officers,
employees and agents. The Company has adopted a by-law with such an indemnity.

Market Risks

     Volatility of Share Price.  The market price of the Company's  shares since
its initial public offering in February 1988 has been volatile. In July 1995 the
Company  effected a one-for-ten  reverse  stock split.  As recently as the first
quarter  of 1993,  the market  price of the  Company's  Common  Stock was $63.75
(giving  retroactive  effect  to the  reverse  stock  split).  Factors  such  as
announcements  of  technological  innovations or new commercial  products by the
Company  or  its  competitors,  the  results  of  clinical  testing,  patent  or
proprietary rights,  developments or other matters may have a significant impact
on the market price of the Common Stock.

     Authorization of Preferred  Stock. The Company's  Articles of Incorporation
authorize the issuance of 2,000,000 shares of "blank check" preferred stock (the
"Preferred  Stock") with such  designations,  rights and  preferences  as may be
determined from time to time by the Board of Directors.  Accordingly,  the Board
of Directors is empowered,  without  stockholder  approval,  to issue  Preferred
Stock  with  dividend,  liquidation,  conversion  or other  rights  which  could
adversely  affect the voting  power or other rights of the holders of the Common
Stock. In the event of issuance, the

                                      -11-

<PAGE>



Preferred Stock could be utilized,  under certain circumstances,  as a method of
discouraging,  delaying or preventing a change of control of the Company.  There
are currently 60,000 shares of Series A Convertible Exchangeable Preferred Stock
outstanding.

     Underwriter Warrants and Outstanding  Convertible  Securities.  The Company
sold to the Underwriter,  for nominal consideration,  warrants to purchase up to
570 Units  exercisable for a period of four years,  commencing one year from the
date of sale,  at an exercise  price of $1,200 per Unit. In addition to warrants
issued in the Public Offering,  the Company currently has outstanding  2,542,697
options and warrants to purchase  Common Stock at exercise  prices  ranging from
$2.50 to $177.50.  The holders of the  Underwriter  Warrants and of the warrants
and options  are likely to  exercise or convert  them at a time when the Company
would be able to obtain  additional  equity capital on terms more favorable than
those  provided  by  such  warrants,   options  and  Underwriter  Warrants.  The
Underwriter  Warrants and certain  other  warrants and options also grant to the
holders certain demand registration rights and "piggy back" registration rights.
These obligations may hi
nder the Company's ability to obtain future financing.

     Lack of Dividends; Inability to Fund Dividend Payments. The Company has not
paid  dividends on its Common Stock since its  inception  and does not intend to
pay any dividends on its Common Stock in the foreseeable  future. The holders of
the Company's outstanding Series A Preferred Stock have been entitled to receive
cumulative  dividends,  payable annually on October 15, since 1992, out of funds
legally available therefor at the rate of $2.25 per year on each share of Series
A Preferred Stock. As of December 31, 1996 and 1995,  230,000 out of the 290,000
Series A Preferred  Stock had been  converted into 51,200 shares of Common Stock
and all 340,000  shares of the Series B Preferred  Stock had been converted into
56,100  shares of Common  Stock.  The Company  exercised its right to adjust the
conversion  rate of the  Series  A  Preferred  Stock  in lieu of  paying  annual
dividend  payments due  commencing  October 15, 1992.  The  conversion  rate was
adjusted by the Company from an initial conversion rate of approximately  .21739
shares  of  Common  Stock  for each  share  of  Series  A  Preferred  Stock to a
conversion rate of .3088.  The Company also adjusted the conversion rate for the
Series B Preferred  Stock from an initial  conversion  rate of .15625  shares of
Common Stock for each share of Series B Preferred  Stock to a conversion rate of
 .1703.  The  arrearages on the payment of dividends  have the effect of limiting
the payment of cash dividends to holders of Common Stock and giving the Series A
Preferred Stockholders,  as a class, the right to designate two directors. As of
the date hereof,  the holders of the Series A Preferred Stock have not exercised
their right to elect such  directors.  There can be no assurance  that cash flow
from the future  operations  of the  Company  will be  sufficient  to meet these
obligations.  Under the terms of the Indenture,  the Company is restricted  from
paying cash dividends on its capital stock.



                                      -12-

<PAGE>



                                 USE OF PROCEEDS

     The  Company  will not receive  any  proceeds  from the sale of the Selling
Stockholders' Shares.

                  SELLING STOCKHOLDERS AND PLAN OF DISTRIBUTION

     The Company has issued or may issue an  aggregate  of  2,103,150  shares of
Common Stock to the Selling Stockholders that are being offered pursuant to this
Prospectus.  The Selling Stockholders have advised the Company that sales of the
shares of Common Stock may be effected  from time to time by  themselves,  their
pledgees  and/or  their  donees,  in  transactions   (which  may  include  block
transactions) on the American Stock Exchange, the Pacific Exchange, Inc., on the
over-the-counter  market,  in  negotiated  transactions,  through the writing of
options on the Common Stock or a  combination  of such methods of sale, at fixed
prices that may be changed,  at market prices prevailing at the time of sale, or
at negotiated  prices.  The Selling  Stockholders,  their pledgees  and/or their
donees,  may effect  such  transactions  by selling  Common  Stock  directly  to
purchasers or through broker-dealers that may act as agents or principals.  Such
broker-dealers may receive compensation in the form of discounts, concessions or
commission  from the Selling  Stockholders  and/or the  purchasers  of shares of
Common Stock for whom such broker-dealers may act as agents or to whom they sell
as  principals,  or both (which  compensation  as to a particular  broker-dealer
might be in excess of customary commissions). The Company has agreed to bear all
expenses in connection with the registration of the Shares.

     The Selling  Stockholders,  their  pledgees  and/or their  donees,  and any
broker-dealers  that act in  connection  with the sale of the  shares  of Common
Stock as  principals  may be deemed to be  "underwriters"  within the meaning of
Section 2(11) of the Securities Act and any commissions received by them and any
profit on the resale of the shares of Common Stock as principals might be deemed
to be  underwriting  discounts and  commissions  under the  Securities  Act. The
Selling Stockholders, their pledgees and/or their donees, may agree to indemnify
any agent,  dealer or broker-dealer that participates in transactions  involving
sales of the  shares of Common  Stock  against  certain  liabilities,  including
liabilities arising under the Securities Act.

     The following table sets forth certain  information with respect to persons
for whom the Company is registering the Selling  Stockholders' Shares for resale
to the public.  Beneficial ownership of the Selling Stockholders' Shares by such
Selling  Stockholders  after the  offering  will depend on the number of Selling
Stockholders' Shares sold by each Selling Stockholder.




                                      -13-

<PAGE>


<TABLE>


                                                                                            Beneficial
                                               Beneficial                                   Ownership
                                               Ownership                                  After Offering if
                                           Prior to Offering            Maximum           Maximum is Sold
                                           -----------------            Amount to         ---------------
Selling Stockholder                          Amount        Percent      be Sold       Amount       Percent
- -------------------                          ------        -------      -------       ------       -------
<S>             <C>                          <C>            <C>         <C>           <C>             
                                                                
James R. Murphy (1)                          661,787        16.52       653,000       8,787          *
Robert M. Stote (2)                          591,800        15.02       572,500      19,300          *
Michael D. Price (3)                         434,803        11.49       432,500       2,303          *
Walter Light (4)                             550,594        14.89       350,000     200,594         5.42
Plexus Ventures, Inc. (5)                     30,000          *          30,000           0          0
Ranald Stewart, Jr. (6)                       40,400         1.19        40,000         400          *
Jeffery Harris (7)                             6,400          *           6,400           0          0
Ronald Trahan Associates, Inc. (8)            18,750          *          18,750           0          0
- ----------------------                                                              
* Less than one percent                                                           

</TABLE>

(1)    Mr.  Murphy's  shares  include  653,000  shares of Common Stock which Mr.
       Murphy has the right to acquire  pursuant to stock options;  3,000 shares
       of Common  Stock  which Mr.  Murphy has the right to acquire  pursuant to
       stock  purchase  warrants;  and 1,200  shares of Common  Stock  which Mr.
       Murphy has the right to acquire upon the  conversion  of 12%  Convertible
       Debentures.  Mr. Murphy is the Chairman of the Board, President and Chief
       Executive Officer and a Director of the Company.

(2)    Dr. Stote's shares include 572,500 shares of Common Stock which Dr. Stote
       has the right to acquire  pursuant  to stock  options;  15,000  shares of
       Common Stock which Dr.  Stote has the right to acquire  pursuant to stock
       purchase  warrants;  and 4,000 shares of Common Stock which Dr. Stote has
       the right to acquire upon the conversion of 12%  Convertible  Debentures.
       Dr.  Stote is the Senior  Vice  President,  Chief  Science  Officer and a
       Director of the Company.

(3)    Mr. Price's shares include 432,500 shares of Common Stock which Mr. Price
       has the right to  acquire  pursuant  to stock  options;  1,500  shares of
       Common Stock which Mr.  Price has the right to acquire  pursuant to stock
       purchase warrants; and 400 shares of Common Stock which Mr. Price has the
       right to acquire upon the conversion of 12% Convertible  Debentures.  Mr.
       Price  is  the  Vice  President,  Chief  Financial  Officer,   Secretary,
       Treasurer and a Director of the Company.

(4)    Mr. Light's shares include 350,000 shares of Common Stock which Mr. Light
       has the right to acquire pursuant to stock purchase warrants.

(5)    The shares of Plexus  Ventures,  Inc.  represent  shares earned by Plexus
       Ventures,  Inc. as compensation for consulting  services  rendered to the
       Company.

(6)    Mr.  Stewart's  shares  include  40,000  shares of Common Stock which Mr.
       Stewart has the right to acquire  pursuant to stock options.  Mr. Stewart
       was a former Officer and Director of the Company.

(7)    Mr.  Harris'  shares  represent  shares of Common Stock which Mr.  Harris
       received from Mr. Stewart in partial settlement of a judgment against Mr.
       Stewart.

(8)    The shares of Ronald Trahan  Associates,  Inc. represent shares of Common
       Stock  which  Ronald  Trahan  Associates,  Inc.  has the right to acquire
       pursuant to stock purchase warrants earned as compensation for consulting
       services rendered to the Company.



                                      -14-

<PAGE>



                            DESCRIPTION OF SECURITIES

Common Stock

     The Company is authorized to issue  35,000,000  shares of Common Stock, par
value $.02 per share.  The holders of Common Stock are entitled to cast one vote
for each share held at all stockholder meetings for all purposes,  including the
election  of  directors,  and to  share  equally  on a per  share  basis in such
dividends  as may be declared  by the Board of  Directors  out of funds  legally
available therefor.  Upon liquidation or dissolution,  each outstanding share of
Common  Stock will be  entitled  to share  equally in the assets of the  Company
legally  available for  distribution to  stockholders,  after the payment of all
debts  and  other  liabilities  and any  payments  due to  holders  of shares of
Preferred Stock.

     No  holder  of  Common  Stock has a  preemptive  or  preferential  right to
purchase or subscribe  for any unissued or  additional  authorized  stock or any
securities of the Company convertible into shares of its Common Stock.

     The Common Stock does not have  cumulative  voting  rights which means that
the  holders of more than 50% of the Common  Stock  voting for the  election  of
directors  can elect 100% of the  directors  of the Company if they choose to do
so.  The  By-Laws  of the  Company  require  that a  majority  of the issued and
outstanding  shares of the Company be  represented  to  constitute  a quorum and
transact business at a stockholders' meeting.

     In accordance with the Amended and Restated  Articles of  Incorporation  of
the Company,  as amended,  the Board of Directors of the Company is divided into
three classes, with the classes as nearly equal in number as possible.  The term
of each class of directors is three years,  with the term of one class  expiring
each year in rotation.  The consent of the holders of 66 2/3% of all outstanding
shares is required to fill a vacancy on the Board of Directors  created by death
or  resignation  or to  remove a  director,  and  then  only  for  cause.  These
provisions are designed to provide continuity of directors.  In addition, a vote
of 66 2/3% of all outstanding  shares is required to approve a merger, a sale of
substantially all of the Company's assets and similar transactions,  or to amend
any provision of the Amended and Restated Articles of Incorporation  relating to
officers and directors.

Transfer Agent, Registrar and Warrant Agent

     The Transfer  Agent and  Registrar  for the Common Stock is American  Stock
Transfer & Trust Company, 40 Wall Street, New York, New York 10005.

                                      -15-

<PAGE>



                                  LEGAL MATTERS

     Parker  Chapin  Flattau & Klimpl,  LLP,  New York,  New York,  is acting as
counsel to the  Company  and is passing on the  validity of the shares of Common
Stock offered hereby.

                                     EXPERTS

     The consolidated  financial  statements and the related financial statement
schedule of the Company  incorporated  in this  Prospectus by reference from the
Company's  Annual Report on Form 10-K for the year ended December 31, 1996, have
been audited by Deloitte & Touche LLP, independent  auditors, as stated in their
reports which are incorporated herein by reference and have been so incorporated
in reliance upon the reports of such firm, given upon their authority as experts
in accounting and auditing.

                                      -16-

<PAGE>



- --------------------------------------------           ---------------------
No dealer,  salesperson  or any other person              2,103,150 Shares  
has been  authorized to give any information                                
or to make any  representation not contained                  BENTLEY       
in this  Prospectus  and,  if given or made,           PHARMACEUTICALS, INC.
such information or representation  must not                                
be relied upon as having been  authorized by                Common Stock    
the company,  by the Selling  Stockholder or                                
by any other person.  This  Prospectus  does                                
not   constitute  an  offer  to  sell  or  a                                
solicitation   of  an   offer   to  buy  the                                
securities  offered  hereby to any person or                                
by anyone in any  jurisdiction in which such                                
offer or  solicitation  may not  lawfully be                                
made.   Neither   the   delivery   of   this                                
Prospectus   nor  any  sale  made  hereunder                                
shall, under any  circumstances,  create any                                
implication that there has been no change in                                
the  affairs of the  Company  since the date                                
hereof.                                              
                                                     
                                                     
                                                     
          -----------------                          
          TABLE OF CONTENTS                          
                                                     
                                        Page                 ----------       
                                        ----                 PROSPECTUS       
                                                             ----------       
Available Information......................3                                  
Incorporation of Certain Documents                                            
     by Reference..........................3                                  
Prospectus Summary.........................5                                  
Risk Factors...............................6                                  
Use of Proceeds...........................13                                  
Selling Stockholders and Plan of                                              
     Distribution.........................13                                  
Description of Securities.................15                                  
Legal Matters.............................16                                  
Experts...................................16                                  
                                                            June __, 1997     
- --------------------------------------------           ---------------------  
                                                                              
                                                     

<PAGE>



                                     PART II

                     INFORMATION NOT REQUIRED IN PROSPECTUS

Item 14.  Other Expenses of Issuance and Distribution.
          --------------------------------------------

     It is estimated that the following  expenses will be incurred in connection
with the proposed  offering filed hereby.  All of such expenses will be borne by
the Company.

Registration fee - Securities
               and Exchange Commission..............         $ 2,171.00
Legal fees and expenses  ...........................           7,500.00
Accounting fees and expenses........................           2,500.00
Printing expenses...................................             100.00
Miscellaneous.......................................             229.00

               Total................................         $12,500.00
                                                            ===========


Item 15.  Indemnification of Directors and Officers.
          ------------------------------------------

     Section 607.0850 of the Florida 1989 Business  Corporation Act is set forth
below:

ss.607.0850 INDEMNIFICATION OF OFFICERS, DIRECTORS, EMPLOYEES, AND AGENTS. (1) A
corporation  shall have the power to indemnify  any person who was or is a party
to  any  proceeding  (other  than  an  action  by,  or  in  the  right  of,  the
corporation),  by  reason  of the fact  that he is or was a  director,  officer,
employee, or agent of the corporation or is or was serving at the request of the
corporation as a director,  officer,  employee, or agent of another corporation,
partnership,  joint  venture,  trust,  or  other  enterprise  against  liability
incurred in connection with such proceeding, including any appeal thereof, if he
acted in good  faith and in a manner  he  reasonably  believed  to be in, or not
opposed to, the best  interests  of the  corporation  and,  with  respect to any
criminal  action or proceeding,  had no reasonable  cause to believe his conduct
was unlawful. The termination of any proceeding by judgment,  order, settlement,
or conviction or upon a plea of nolo contendere or its equivalent  shall not, of
itself,  create a presumption that the person did not act in good faith and in a
manner  which he  reasonably  believed  to be in, or not  opposed  to,  the best
interests  of the  corporation  or,  with  respect  to any  criminal  action  or
proceeding, had reasonable cause to believe that his conduct was unlawful.

     (2) A corporation shall have power to indemnify any person, who was or is a
party to any  proceeding  by or in the  right of the  corporation  to  procure a
judgment  in its  favor  by  reason  of the fact  that he is or was a  director,
officer,  employee,  or agent of the  corporation  or is or was  serving  at the
request of the corporation as a director, officer, employee, or agent of another
corporation,  partnership,  joint venture,  trust, or other enterprise,  against
expenses and amounts paid in settlement  not  exceeding,  in the judgment of the
board of  directors,  the  estimated  expense of  litigating  the pro ceeding to
conclusion,  actually and reasonably  incurred in connection with the defense or
settlement   of  such   proceeding,   including   any   appeal   thereof.   Such
indemnification shall be authorized if such

                                      II-1

<PAGE>



person acted in good faith and in a manner he  reasonably  believed to be in, or
not  opposed  to,  the  best  interests  of  the  corporation,  except  that  no
indemnification  shall be made  under this  subsection  in respect of any claim,
issue,  or matter as to which such person shall have been  adjudged to be liable
unless,  and only to the extent  that,  the court in which such  proceeding  was
brought,  or any other court of competent  jurisdiction,  shall  determine  upon
application  that,  despite the  adjudication  of  liability  but in view of all
circumstances  of the case,  such  person is fairly and  reasonably  entitled to
indemnity for such expenses which such court shall deem proper.

     (3)  To the  extent  that a  director,  officer,  employee  or  agent  of a
corporation  has been  successful  on the merits or  otherwise in defense of any
proceeding referred to in subsection (1) or subsection (2), or in defense of any
claim,  issue,  or matter  therein,  he shall be  indemnified  against  expenses
actually and reasonably incurred by him in connection therewith.

     (4) Any  indemnification  under  subsection (1) or subsection  (2),  unless
pursuant to a determination by a court, shall be made by the corporation only as
authorized in the specific case upon a determination that indemnification of the
director,  officer, employee, or agent is proper in the circumstances because he
has met the  applicable  standard  of  conduct  set forth in  subsection  (1) or
subsection (2). Such determination shall be made:

          (a)  By  the  board  of  directors  by a  majority  vote  of a  quorum
consisting of directors who were not parties to such proceeding;

          (b) If such a quorum is not  obtainable  or,  even if  obtainable,  by
majority vote of a committee duly designated by the board of directors (in which
directors  who are parties  may  participate)  consisting  solely of two or more
directors not at the time parties to the proceeding;

          (c) By independent legal counsel:

               1. Selected by the board of directors prescribed in paragraph (a)
or the committee prescribed in paragraph (b); or

               2. If a quorum of the directors  cannot be obtained for paragraph
(a) and the committee  cannot be designated  under  paragraph  (b),  selected by
majority vote of the full board of directors (in which directors who are parties
may participate); or

          (d) By the  stockholders by a majority vote of a quorum  consisting of
stockholders  who were not parties to such  proceeding  or, if no such quorum is
obtainable,  by a majority  vote of  stockholders  who were not  parties to such
proceeding.

     (5)  Evaluation  of the  reasonableness  of expenses and  authorization  of
indemnification  shall  be made in the same  manner  as the  determination  that
indemnification is permissible.  However, if the determination of permissibility
is made by independent  legal  counsel,  persons  specified by paragraph  (4)(c)
shall evaluate the reasonableness of expenses and may authorize indemnification.


                                      II-2

<PAGE>



     (6)  Expenses  incurred by an officer or  director in  defending a civil or
criminal  proceeding  may be paid by the  corporation  in  advance  of the final
disposition of such proceeding upon receipt of an undertaking by or on behalf of
such director or officer to repay such amount if he is  ultimately  found not to
be entitled to  indemnification  by the  corporation  pursuant to this  section.
Expenses incurred by other employees and agents may be paid in advance upon such
terms or conditions that the board of directors deems appropriate.

     (7) The  indemnification  and advancement of expenses  provided pursuant to
this section are not exclusive,  and a corporation may make any other or further
indemnification  or advancement  of expenses of any of its directors,  officers,
employees,  or  agents,  under any bylaw,  agreement,  vote of  stockholders  or
disinterested  directors,  or  otherwise,  both  as to  action  in his  official
capacity  and as to  action in  another  capacity  while  holding  such  office.
However,  indemnification  or advancement of expenses shall not be made to or on
behalf  of any  director,  officer,  employee,  or agent if a judg ment or other
final  adjudication  establishes  that his actions,  or  omissions to act,  were
material to the cause of action so adjudicated and constitute:

          (a) A violation of the criminal  law,  unless the  director,  officer,
employee, or agent had reasonable cause to believe his conduct was lawful or had
no reasonable cause to believe his conduct was unlawful;

          (b) A transaction from which the director, officer, employee, or agent
derived an improper personal benefit;

          (c)  In the  case  of a  director,  a  circumstance  under  which  the
liability provisions of s. 607.0834 are applicable; or

          (d) Willful misconduct or a conscious disregard for the best interests
of the  corporation  in a proceeding  by or in the right of the  corporation  to
procure  a  judgment  in its  favor or in a  proceeding  by or in the right of a
stockholder.

     (8) Indemnification and advancement of expenses as provided in this section
shall continue as, unless otherwise  provided when authorized or ratified,  to a
person who has ceased to be a director,  officer,  employee,  or agent and shall
inure to the  benefit  of the heirs,  executors,  and  administrators  of such a
person, unless otherwise provided when authorized or ratified.

     (9) Unless the corporation's  articles of incorporation  provide otherwise,
notwithstanding  the failure of a corporation  to provide  indemnification,  and
despite any contrary  determination  of the board or of the  stockholders in the
specific case, a director, officer, employee, or agent of the corporation who is
or was a party to a proceeding may apply for  indemnification  or advancement of
expenses, or both, to the court conducting the proceeding, to the circuit court,
or to another court of competent jurisdiction. On receipt of an application, the
court,  after  giving  any  notice  that  it  considers  necessary,   may  order
indemnification  and  advancement of expenses,  including  expenses  incurred in
seeking  court-ordered   indemnification  or  advancement  of  expenses,  if  it
determines that:


                                      II-3

<PAGE>



          (a) The director, officer, employee, or agent is entitled to mandatory
indemnification  under  subsection (3), in which case the court shall also order
the corporation to pay the director  reasonable  expenses  incurred in obtaining
court-ordered indemnification or advancement of expenses;

          (b)  The  director,   officer,  employee,  or  agent  is  entitled  to
indemnification  or advancement of expenses,  or both, by virtue of the exercise
by the corporation of its power pursuant to subsection (7); or

          (c) The director, officer, employee, or agent is fairly and reasonably
entitled to indemnification or advancement of expenses,  or both, in view of all
the relevant  circumstances,  regardless of whether such person met the standard
of conduct set forth in subsection (1), subsection (2), or subsection (7).

     (10) For purposes of this  section,  the term  "corporation"  includes,  in
addition to the resulting  corporation,  any constituent  corporation (including
any constituent of a constituent) absorbed in a consolidation or merger, so that
any  person  who  is  or  was a  director,  officer,  employee,  or  agent  of a
constituent  corporation,  or is or was serving at the request of a  constituent
corporation as a director,  officer,  employee, or agent of another corporation,
partnership,  joint venture, trust, or other enterprise, is in the same position
under this section with respect to the resulting or surviving  corporation as he
would  have  with  respect  to  such  constituent  corporation  if its  separate
existence had continued.

     (11) For purposes of this section:

          (a) The term "other enterprises" includes employee benefit plans;

          (b) The term  "expenses"  includes  counsel fees,  including those for
appeal;

          (c) The  term  "liability"  includes  obligations  to pay a  judgment,
settlement,  penalty, fine (including an excise tax assessed with respect to any
employee  benefit  plan),  and expenses  actually and  reasonably  incurred with
respect to a proceeding;

          (d)  The  term  "proceeding"  includes  any  threatened,  pending,  or
completed action,  suit, or other type of proceeding,  whether civil,  criminal,
administrative, or investigative and whether formal or informal;

          (e) The term "agent" includes a volunteer;

          (f) The term "serving at the request of the corporation"  includes any
service as a  director,  officer,  employee,  or agent of the  corporation  that
imposes duties on such persons, including duties relating to an employee benefit
plan and its participants or beneficiaries; and


                                      II-4

<PAGE>



          (g) The term "not  opposed to the best  interest  of the  corporation"
describes  the  actions  of a person  who acts in good  faith and in a manner he
reasonably  believes  to be in  the  best  interests  of  the  participants  and
beneficiaries of an employee benefit plan.

     (12) A corporation  shall have power to purchase and maintain  insurance on
behalf of any person who is or was a director,  officer,  employee,  or agent of
the  corporation  or is or was  serving at the request of the  corporation  as a
director, officer, employee, or agent of another corporation, partnership, joint
venture,  trust, or other enterprise  against any liability asserted against him
and  incurred by him in any such  capacity or arising out of his status as such,
whether or not the  corporation  would have the power to  indemnify  him against
such liability under the provisions of this section.

                                    * * * * *

     Article  IV  of  the  Company's   By-laws   contains   provisions  for  the
indemnification  of  officers,  directors,  employees  and agents to the fullest
extent permitted by Section 607.0850.

     There is in effect a directors and officers liability insurance policy with
Lexington  Insurance  Company.  The policy insures the directors and officers of
the Company  against loss arising from certain claim or claims made against such
directors or officers by reason of certain  wrongful acts.  The policy  provides
combined  limit of liability of $2,000,000  per policy year for both  directors'
and officers' liability coverage at an annual premium of $117,600.

Item 16.                Exhibits.
                        ---------

Exhibit
Number                              Description
- ------                              -----------

3.1       Articles of Incorporation of the Registrant,  as amended and restated.
          (Reference is made to Exhibit 3.1 to the Registrant's  Amendment No. 1
          on Form S-3 to Form S-1  Registration  Statement,  Commission File No.
          33-65125, which exhibit is incorporated herein by reference.)

3.2       By-Laws of the Registrant, as amended and restated. (Reference is made
          to Exhibit 3.2 to the Registrant's Form 10-K for the period ended June
          30, 1989,  Commission File No. 1-10581,  which exhibit is incorporated
          herein by reference.)

3.3       Amendment to By-Laws of the Registrant.  (Reference is made to Exhibit
          3.2(a)  to the  Company's  Amendment  No.  1 on Form  S-3 to Form  S-1
          Registration Statement, Commission File No. 33-35941, which exhibit is
          incorporated herein by reference.)

4.1       Registrant's 1991 Stock Option Plan. (Reference is made to Exhibit 4.6
          to the Registrant's  Form 8-K filed October 17, 1991,  Commission File
          No. 1-10581, which exhibit is incorporated herein by reference.)

                                      II-5

<PAGE>



4.2       Amendment to Registrant's  1991 Stock Option Plan.  (Reference is made
          to  Exhibit  4.17 to the  Registrant's  Form  10-K for the  Transition
          Period Ended December 31, 1992,  Commission  File No.  1-10581,  which
          exhibit is incorporated herein by reference.)

4.3       Amendment  to  Registrant's  1991 Stock Option Plan as approved by the
          stockholders  on June 9, 1994.  (Reference  is made to Exhibit 4.16 to
          the  Registrant's  Form 10-K for the year  ended  December  31,  1994,
          Commission File No. 1-10581,  which exhibit is incorporated  herein by
          reference.)

4.4       Form of  Non-qualified  Stock Option  Agreement under the Registrant's
          1991 Stock  Option  Plan.  (Reference  is made to Exhibit  4.25 to the
          Registrant's  Form  10-K  dated  June 30,  1992,  Commission  File No.
          1-10581, which exhibit is incorporated herein by reference.)

4.5(1)    Form of Nonqualified Performance Vesting Stock Option Contract between
          the Registrant and certain Executive Officers.

4.6(1)    Form of Warrant  Agreement  between the  Registrant  and Walter  Light
          dated August 27, 1996.

4.7(1)    Consulting Agreement between the Registrant and Plexus Ventures,  Inc.
          dated October 15, 1996.

4.8(1)    Warrant Agreement between the Registrant and Ranald Stewart, Jr. dated
          June 9, 1995.

4.9(1)    Consulting   Agreement   between  the  Registrant  and  Ronald  Trahan
          Associates, Inc. dated May 13, 1996.

5.1(1)    Opinion of Parker Chapin Flattau & Klimpl, LLP.

23.1(1)   Consent of Deloitte & Touche LLP.

23.2(1)   Consent of Parker  Chapin  Flattau & Klimpl,  LLP (included in Exhibit
          5.1 hereto).

24.1(1)   Power of Attorney (see page II-8 of this Registration Statement).

- --------------------
(1)     Filed herewith.



                                      II-6

<PAGE>



Item 17.  Undertakings.
          -------------

     The undersigned Company hereby undertakes:

     (1) To file,  during any period in which  offers or sales are being made, a
post-effective  amendment to this registration statement to include any material
information with respect to the plan of distribution not previously disclosed in
the  registration  statement or any material  change to such  information in the
registration statement;

     (2) That, for the purpose of determining any liability under the Securities
Act of 1933,  each  such  post-effective  amendment  shall be deemed to be a new
registration  statement  relating to the  securities  offered  therein,  and the
offering of such  securities at that time shall be deemed to be the initial bona
fide offering thereof;

     (3) To remove from registration by means of a post-effective  amendment any
of the securities being registered which remain unsold at the termination of the
offering; and

     (4) That,  for purposes of determining  any liability  under the Securities
Act of 1933, each filing of the  registrant's  annual report pursuant to section
13(a) or  section  15(d) of the  Securities  Exchange  Act of 1934  (and,  where
applicable,  each filing of an employee benefit plan's annual report pursuant to
section 15(d) of the Securities  Exchange Act of 1934) that is  incorporated  by
reference  in  this  registration   statement  shall  be  deemed  to  be  a  new
registration  statement  relating  to the  securities  offered  herein,  and the
offering of such  securities at that time shall be deemed to be the initial bona
fide offering thereof.

                                      II-7

<PAGE>



                                   SIGNATURES

     Pursuant to the  requirements of the Securities Act of 1933, the Registrant
certifies  that it has  reasonable  grounds to believe  that it meets all of the
requirements  for  filing  on Form S-3 and has  duly  caused  this  Registration
Statement  to be  signed  on its  behalf  by  the  undersigned,  thereunto  duly
authorized,  in the City of  Tampa,  State of  Florida,  on the 30th day of May,
1997.

                                  Bentley Pharmaceuticals, Inc.


                                  By  /s/ James R. Murphy
                                      -------------------
                                          James R. Murphy
                                          Chairman of the Board, President and
                                          Chief Executive Officer


                                POWER OF ATTORNEY

     KNOW ALL  PERSONS  BY THESE  PRESENTS,  that each  person  whose  signature
appears below constitutes and appoints each of James R. Murphy,  Robert M. Stote
and Michael D. Price and each of them with power of substitution,  as his or her
attorney-in-fact, in all capacities, to sign any amendments to this registration
statement  (including  post-effective  amendments)  and to file the  same,  with
exhibits  thereto  and  other  documents  in  connection  therewith,   with  the
Securities  and Exchange  Commission,  hereby  ratifying and confirming all that
said attorney-in-facts or their substitutes may do or cause to be done by virtue
hereof.

     Pursuant  to  the   requirements  of  the  Securities  Act  of  1933,  this
Registration  Statement  has  been  signed  by  the  following  persons  in  the
capacities and on the date indicated.

   Signature                  Title                                 Date
   ---------                  -----                                 ----


/s/ James R. Murphy      Chairman of the Board,                  May 30, 1997
- -------------------      President, Chief Executive
James R. Murphy          Officer and Director


/s/ Robert M. Stote      Senior Vice-President, Chief            May 30, 1997
- -------------------      Science Officer and Director
Robert M. Stote



                                      II-8

<PAGE>



/s/ Michael D. Price     Vice-President, Chief                   May 30, 1997
- --------------------     Financial Officer, Secretary,
Michael D. Price         Treasurer and Director
                         (principal financial and
                         accounting officer)


/s/ Randolph W. Arnegger Director                                May 30, 1997
- ------------------------
Randolph W. Arnegger


/s/ Charles L. Bolling   Director                                May 30, 1997
- ----------------------
Charles L. Bolling


/s/ Doris E. Wardell     Director                                May 30, 1997
- --------------------
Doris E. Wardell




                                      II-9

<PAGE>



Exhibit
Number                      Description
- ------                      -----------

3.1         Articles  of  Incorporation  of  the  Registrant,   as  amended  and
            restated.  (Reference  is made to  Exhibit  3.1 to the  Registrant's
            Amendment  No.  1 on Form S-3 to Form  S-1  Registration  Statement,
            Commission File No. 33-65125,  which exhibit is incorporated  herein
            by reference.)

3.2         By-Laws of the  Registrant,  as amended and restated.  (Reference is
            made to  Exhibit  3.2 to the  Registrant's  Form 10-K for the period
            ended June 30, 1989,  Commission File No. 1-10581,  which exhibit is
            incorporated herein by reference.)

3.3         Amendment  to  By-Laws  of the  Registrant.  (Reference  is  made to
            Exhibit 3.2(a) to the Company's  Amendment No. 1 on Form S-3 to Form
            S-1  Registration  Statement,  Commission File No.  33-35941,  which
            exhibit is incorporated herein by reference.)

4.1         Registrant's  1991 Stock Option Plan.  (Reference is made to Exhibit
            4.6 to the Registrant's Form 8-K filed October 17, 1991,  Commission
            File  No.  1-10581,   which  exhibit  is   incorporated   herein  by
            reference.)

4.2         Amendment to Registrant's 1991 Stock Option Plan. (Reference is made
            to Exhibit  4.17 to the  Registrant's  Form 10-K for the  Transition
            Period Ended December 31, 1992,  Commission File No. 1-10581,  which
            exhibit is incorporated herein by reference.)

4.3         Amendment to Registrant's  1991 Stock Option Plan as approved by the
            stockholders on June 9, 1994.  (Reference is made to Exhibit 4.16 to
            the  Registrant's  Form 10-K for the year ended  December  31, 1994,
            Commission File No. 1-10581, which exhibit is incorporated herein by
            reference.)

4.4         Form of Non-qualified  Stock Option Agreement under the Registrant's
            1991 Stock  Option Plan.  (Reference  is made to Exhibit 4.25 to the
            Registrant's  Form 10-K dated  June 30,  1992,  Commission  File No.
            1-10581, which exhibit is incorporated herein by reference.)

4.5(1)      Form of  Nonqualified  Performance  Vesting  Stock  Option  Contract
            between the Registrant and certain Executive Officers.


                                      II-10

<PAGE>



4.6(1)      Form of Warrant  Agreement  between the  Registrant and Walter Light
            dated August 27, 1996.

4.7(1)      Consulting  Agreement  between the Registrant  and Plexus  Ventures,
            Inc. dated October 23, 1996.

4.8(1)      Warrant  Agreement  between the Registrant and Ranald  Stewart,  Jr.
            dated June 9, 1995.

4.9(1)      Consulting  Agreement  between  the  Registrant  and  Ronald  Trahan
            Associates, Inc. dated May 13, 1996.

5.1(1)      Opinion of Parker Chapin Flattau & Klimpl, LLP.

23.1(1)     Consent of Deloitte & Touche LLP.

23.2(1)     Consent of Parker Chapin Flattau & Klimpl,  LLP (included in Exhibit
            5.1 hereto).

24.1(1)     Power of Attorney  (see page II-8 of this  Registration  Statement).

- -------------------- 
(1) Filed herewith.


                                      II-11





                                                                    Exhibit 4.5
                                                                    -----------

                          BENTLEY PHARMACEUTICALS, INC.
             NONQUALIFIED PERFORMANCE VESTING STOCK OPTION CONTRACT
             ------------------------------------------------------

     THIS NONQUALIFIED PERFORMANCE VESTING STOCK OPTION CONTRACT entered into on
this 19TH day of April, 1996, between BENTLEY  PHARMACEUTICALS,  INC., a Florida
corporation (the "Company"), and ____________________ (the "Optionee").

                              W I T N E S S E T H :
                              - - - - - - - - - -

     1. The Company grants,  as of the date hereof,  to the Optionee  options to
purchase an aggregate  of Six Hundred  Thousand  (600,000)  shares of the Common
Stock,  $.02 par value per share,  of the  Company  (the  "Common  Stock")  with
one-third of such  options  vesting and  becoming  exercisable  when the closing
price of the Company's  Common Stock on the American  Stock  Exchange  equals or
exceeds the exercise price of $2.89 (being 110% of the fair market value of such
shares of Common Stock on the date hereof) for twenty consecutive  trading days;
one-third  when the closing price equals or exceeds the exercise  price of $3.68
(being 140% of the fair market  value of such shares of Common Stock on the date
hereof) for twenty  consecutive  trading days;  and  one-third  when the closing
price  equals or exceeds  the  exercise  price of $4.73  (being 180% of the fair
market  value of such  shares of Common  Stock on the date  hereof)  for  twenty
consecutive trading days. These options shall not be treated as "incentive stock
options"  under Section 422 of the Internal  Revenue Code.  The Company  intends
that such options constitute  Non-Qualified  Stock Options and not be considered
options issued under its existing Stock Option Plans.

     2. The term of these  options  shall be 10 years from the date hereof.  The
right  to  purchase  shares  of  Common  Stock  under  these  options  shall  be
cumulative,  so that if the full number of shares  purchasable in a period shall
not be purchased,  the balance may be purchased at any time or from time to time
thereafter,  but not after the  expiration of the options.  Notwithstanding  the
foregoing,  the options may not be  exercised at any time in an amount less than
100 shares (or the remaining  shares then covered by and  purchasable  under the
options  if less than 100) and in no event may a  fraction  of a share of Common
Stock be purchased under these options.

     3. These options shall be exercised by giving written notice to the Company
at its  principal  office,  presently  One Urban  Centre,  Suite 548,  4830 West
Kennedy Boulevard, Tampa, Florida 33609, Attn: Corporate Secretary, stating that
the Optionee is exercising  these  nonqualified  stock  options,  specifying the
number of shares  being  purchased  and  accompanied  by  payment in full of the
aggregate purchase price therefor (a) in cash, by check, or by any other form of
consideration  permitted by law, (b) with  previously  acquired shares of Common
Stock, or (c) a combination of the foregoing.

     4. The Company shall at all times during the term of these options  reserve
and keep  available  for  issuance or  delivery  such number of shares of Common
Stock as will be sufficient to satisfy the requirements of these options,  shall
pay all original issue taxes or transfer taxes

                                       -1-

<PAGE>



with respect to the  issuance or delivery of shares  pursuant to the exercise of
such options and all other fees and expenses necessarily incurred by the Company
in connection  therewith,  except for required  income tax or other  withholding
amounts.  As long as these options shall be  outstanding,  the Company shall use
its  reasonable  best efforts to cause all shares  issuable upon the exercise of
these  options to be listed  (subject to  official  notice of  issuance)  on all
securities  exchanges on which the shares of the Company's Common Stock may then
be listed and/or quoted on NASDAQ.  The Company agrees to include the underlying
shares of Common Stock issuable upon exercise of these options in a Registration
Statement(s)  to be  filed  by the  Company  with the  Securities  and  Exchange
Commission as soon as is practicable  and will use its best efforts to keep such
Registration  Statement(s)  effective for the entire time that these options are
in effect.  The Company  shall pay all filing  fees,  related  accountants'  and
counsels' fees and all other  registration  expenses  incurred by the Company in
complying with this requirement.

     5. In the event that the number of  outstanding  shares of Common  Stock is
increased or  decreased or changed into a different  number or kind of shares or
securities   by   reason  of  any   merger,   share   exchange,   consolidation,
reorganization, recapitalization,  reclassification, stock split, combination of
shares,  exchange of shares,  stock  dividend or other  distribution  payable in
capital  stock,  or other increase or decrease in such shares  effected  without
receipt of  consideration  by the  Company,  an  adjustment  will be made to the
remaining  outstanding options so that the proportional interest of the Optionee
after such an event will be, to the extent  practicable,  the same as before the
event.

     6. Notwithstanding the foregoing, the Optionee acknowledges that the Common
Stock to be received by him upon the exercise of these options may not be resold
unless (a) a registration statement under the Securities Act of 1933, as amended
(the "Securities Act") with respect to the shares of Common Stock to be received
upon the exercise of the options  shall be effective  and current at the time or
(b) there is an exemption  from  registration  under the  Securities Act for the
issuance  of the shares of Common  Stock.  At the  request of the  Company,  the
Optionee  shall  execute  and  deliver to the  Company  his  representation  and
warranty, in form and substance  satisfactory to the Company, that the shares of
Common Stock to be issued upon the exercise of the options are being acquired by
the Optionee for his own account, for investment only and not with a view to the
resale or  distribution  thereof.  In  addition,  the  Company  may  require the
Optionee to represent and warrant to the Company in writing that any  subsequent
resale  or  distribution  of  shares  of  Common  Stock by him will be made only
pursuant  to (i) a  Registration  Statement  under the  Securities  Act which is
effective  and current with respect to the Shares of Common Stock being sold, or
(ii) a specific  exemption from the registration  requirements of the Securities
Act, but in claiming such  exemption,  the Optionee  shall prior to any offer of
sale or sale of such shares of Common Stock provide the Company with a favorable
written opinion of counsel,  in form and substance  satisfactory to the Company,
as to the applicability of such exemption to the proposed sale or distribution.

     7. The Company may affix  appropriate  legends  upon the  certificates  for
shares of Common Stock issued upon  exercise of these options and may issue such
"stop transfer"  instructions to its transfer agent in respect of such shares as
it determines, in its discretion, to


                                       -2-

<PAGE>



be  necessary  or  appropriate  under  the  registration   requirements  of  the
Securities Act.

     8. The  Company may  withhold  cash  and/or  shares of Common  Stock in the
amount  necessary  to satisfy its  obligation  to withhold  taxes or require the
Optionee to pay the Company such amount in cash promptly upon demand.

     9. In the event that the  employment  with the Company  shall be terminated
for any reason (other than by reason of death or disability),  these options may
be  exercised  (to the extent  that the  Optionee  was  entitled to do so at the
termination  of his  employment)  at any  time  until  the  expiration  of these
options;  provided,  however,  that if the  Company  terminates  the  Optionee's
employment  after a change in control of the  Company,  all  options  shall vest
immediately  and be exercisable  in accordance  with the terms of the Optionee's
employment agreement.  In the event that the employment of the Optionee shall be
terminated by disability,  the remaining  unexercised portion of the options may
be  exercised  by the  Optionee  (notwithstanding  that the  options had not yet
become  exercisable  with  respect to all or part of such  shares at the date of
termination) at any time until the expiration of these options.  If the Optionee
shall die while he is  employed  by the  Company or during the period  following
termination  of  employment  in which the  Optionee  had a right to exercise the
options,  such options may by exercised,  as to all or any part of the remaining
unexercised portion of the options (notwithstanding that the options had not yet
become  exercisable  with respect to all or a part of such shares at the date of
death) by a legatee or legatees of such options under the Optionee's  last will,
or by his personal  representatives  or distributees,  at any time within twelve
months  after his death,  but not  thereafter  and in no event after the date on
which, except for such death, the options would otherwise expire.

     10.  The  Optionee  represents  and  agrees  that he will  comply  with all
applicable  laws  relating to the grant and  exercise  of these  options and the
disposition of the shares of Common Stock acquired upon exercise of the options,
including without limitation, federal and state securities and "blue sky" laws.

     11. These options are not  transferable  otherwise than by will or the laws
of descent and  distribution  and may be  exercised,  during the lifetime of the
Optionee, only by him or his legal representatives.

     12.  This  Contract  shall be binding  upon and inure to the benefit of any
successor  or assign of the  Company  and to any  heir,  distributee,  executor,
administrator or legal  representative  entitled by law to the Optionee's rights
hereunder.

     13. This Contract shall be governed by and construed in accordance with the
laws of the State of Florida.

     14. The  invalidity or illegality of any provision  herein shall not affect
the validity of any other provision.



                                       -3-

<PAGE>


     15. Any notice to be given hereunder  shall be in writing  addressed to the
Company at One Urban  Centre,  Suite 548,  4830 West Kennedy  Boulevard,  Tampa,
Florida 33609, Attention:  Corporate Secretary, and any notice to Optionee shall
be addressed to 4 John Stark Lane, Hampton, New Hampshire 03482 or at such other
address as either party may  hereafter  designate  in writing to the other.  Any
such  notice  shall be deemed to have been duly given if and when  enclosed in a
properly sealed envelope or wrapper,  addressed as aforesaid,  registered,  with
return receipt requested,  and deposited,  first class postage and registry fees
prepaid,  in a post  office or branch post office  regularly  maintained  by the
United States Government.

     16. This Agreement embodies the entire agreement and understanding  between
the  Company  and  the  Optionee  and  supersedes   all  prior   agreements  and
understandings  relating to the subject matter hereof (with the exception of the
Optionee's  Employment  Agreement which governs in the event of termination as a
result of a change of  ownership),  but does not  replace  or have any effect on
other options issued to the Optionee by the Company,  and this Agreement may not
be  modified or amended or any term or  provision  hereof  waived or  discharged
except  in  writing,   signed  by  the  party   against  whom  such   amendment,
modification, waiver or discharge is sought to be enforced.

     IN WITNESS  WHEREOF,  the parties hereto have executed this Contract on the
day and year first above written.


                                                BENTLEY PHARMACEUTICALS, INC.

                                                By:  _________________________


                                                     _________________________
                                                              Optionee


                                       -4-




                                                                    Exhibit 4.6
                                                                    -----------

WARRANT A                                                        August 27, 1996


                          BENTLEY PHARMACEUTICALS, INC.

                     The Transferability of this Warrant is

                       Restricted as Provided in Article 3


     In  consideration  of  $.001  per  Warrant  and  other  good  and  valuable
consideration,   the  receipt  of  which  is  hereby   acknowledged  by  BENTLEY
PHARMACEUTICALS, INC., One Urban Centre, Suite 550, 4830 West Kennedy Boulevard,
Tampa,  Florida 33609, a Florida  corporation  ("the Company"),  Walter Light is
hereby granted the right to purchase, at the initial exercise price of $2.50 per
share,  at any time until 5:00 P.M.,  New York time, on August 27, 2001,  50,000
(fifty thousand) shares of the Company's Common Stock,  $.02 par value per share
("Shares").

     This Warrant initially is exercisable at a price of $2.50 per Share payable
in cash or by certified or official bank check in New York Clearing House funds,
subject to  adjustment as provided in Article 6 hereof.  Upon  surrender of this
Warrant, with the annexed Subscription Form duly executed, together with payment
of the Purchase Price (as hereinafter defined) for the Shares purchased,  at the
offices of the  Company,  the  registered  holder of this  Warrant  ("Holder" or
"Holders")  shall be entitled to receive a certificate or  certificates  for the
Shares so purchased.

1.   Exercise of Warrant.
     --------------------

     The purchase  rights  represented  by this Warrant are

<PAGE>


exercisable at the option of the Holder hereof,  in whole or in part (but not as
to fractional Shares  underlying this Warrant),  during any period in which this
Warrant may be exercised as set forth above. In the case of the purchase of less
than all the Shares  purchasable  under this  Warrant,  the Company shall cancel
this  Warrant  upon the  surrender  hereof and shall  execute  and deliver a new
Warrant of like tenor for the balance of the Shares purchasable hereunder.

2.   Issuance of Certificates.
     -------------------------

     Upon the exercise of this Warrant,  the issuance of certificates for Shares
underlying  this Warrant shall be made  forthwith  (and in any event within five
business days thereafter) without charge to the Holder hereof including, without
limitation, any tax which may be payable in respect of the issuance thereof, and
such  certificates  shall  (subject to the  provisions  of Articles 3 hereof) be
issued  in the name of,  or in such  names as may be  directed  by,  the  Holder
hereof; provided, however, that the Company shall not be required to pay any tax
which may be payable in respect of any  transfer  involved in the  issuance  and
delivery  of any such  certificates  in a name other than that of the Holder and
the Company shall not be required to issue or deliver such  certificates  unless
or until the person or persons  requesting the issuance  thereof shall have paid
to the  Company  the  amount  of  such  tax or  shall  have  established  to the
satisfaction of the Company

                                      -2-

<PAGE>

that such tax has been paid. The certificates representing the Shares underlying
this  Warrant  shall be  executed  on behalf  of the  Company  by the  manual or
facsimile signature of one of the present or any future Chairman or President of
the  Company  and any  present or future  Vice  President  or  Secretary  of the
Company.

3.   Restriction on Transfer of Warrant.
     -----------------------------------

     The Holder of this Warrant, by its acceptance hereof,  covenants and agrees
that this Warrant is being  acquired as an investment and not with a view to the
distribution  hereof,  and  that it may  not be  exercised,  sold,  transferred,
assigned,  hypothecated or otherwise  disposed of, in whole or in part unless in
the opinion of counsel concurred in by the Company's counsel such transfer is in
compliance with all applicable securities laws.

4.   Price.
     ------

     4.1 Initial and Adjusted  Purchase Price.  The initial purchase price shall
be $2.50 per Share.  The adjusted  purchase price shall be the price which shall
result from time to time from any and all  adjustments  of the initial  purchase
price in accordance with the provisions of Article 5 hereof.

     4.2 Purchase Price. The term "Purchase Price" herein shall mean the initial
purchase price or the adjusted purchase price, depending upon the context.


                                       -3-

<PAGE>


5.   Adjustments of Purchase Price and Number of Shares.
     ---------------------------------------------------

     5.1  Subdivision  and  Combination.  In case the Company  shall at any time
subdivide or combine the outstanding  Shares, the Purchase Price shall forthwith
be proportionately decreased in the case of subdivision or increased in the case
of combination.

     5.2  Adjustment in Number of Shares.  Upon each  adjustment of the Purchase
Price  pursuant  to the  provisions  of this  Article  5, the  number  of Shares
issuable upon the exercise of this Warrant shall be adjusted to the nearest full
Share by multiplying a number equal to the Purchase Price in effect  immediately
prior to such  adjustment by the number of Shares issuable upon exercise of this
Warrant  immediately  prior to such  adjustment  and  dividing  the  product  so
obtained by the adjusted Purchase Price.

     5.3   Reclassification,   Consolidation,   Merger,  etc.  In  case  of  any
reclassification or change of the outstanding Shares (other than a change in par
value to no par value,  or from no par value to par  value,  or as a result of a
subdivision or combination),  or in the case of any consolidation of the Company
with,  or  merger  of  the  Company  into,  another  corporation  (other  than a
consolidation  or merger in which the Company is the surviving  corporation  and
which  does not  result in any  reclassification  or  change of the  outstanding
Shares,  except a change as a result of a  subdivision  or  combination  of such
shares  or a change in par  value,  as  aforesaid),  or in the case of a sale or
conveyance to another corporation of the property of the Company as an entirety,
the Holder of this

                                       -4-

<PAGE>


Warrant  shall  thereafter  have the right to purchase upon the exercise of this
Warrant the kind and number of shares of stock and other securities and property
receivable upon such reclassification,  change,  consolidation,  merger, sale or
conveyance as if the Holder were the owner of the Shares underlying this Warrant
immediately prior to any such events at the Purchase Price in effect immediately
prior  to the  record  date for such  reclassification,  change,  consolidation,
merger, sale or conveyance as if such Holder had exercised this Warrant.

6.   Registration Rights.
     --------------------

     The Company hereby agrees,  for one time only, to include the Shares in any
one Registration  Statement (other than a Registration  Statement on Form S-4 or
S-8 or similar or successor  forms) filed by the Company with the Securities and
Exchange  Commission  between  the date hereof and the  expiration  date of this
Warrant.  The  Company  shall pay all  filing  fees,  related  accountants'  and
counsels' fees and all other  registration  expenses  incurred by the Company in
complying  with  this  Section  6;  provided,  however,  that  all  underwriting
discounts and selling commissions applicable to the Shares shall be borne by the
seller or sellers thereof.

7.   Exchange and Replacement of Warrant.
     ------------------------------------

     This Warrant is exchangeable without expense, upon the

                                       -5-

<PAGE>


surrender hereof by the registered  Holder at the principal  executive office of
the  Company  for a new  Warrant  of like  tenor  and date  representing  in the
aggregate  the right to purchase  the same  number of Shares as are  purchasable
hereunder in such  denominations  as shall be designated by the Holder hereof at
the time of such surrender.

     Upon receipt by the Company of evidence  reasonably  satisfactory  to it of
the loss,  theft,  destruction  or mutilation  of this Warrant,  and, in case of
loss, theft or destruction,  of indemnity or security reasonably satisfactory to
it, and  reimbursement  to the  Company of all  reasonable  expenses  incidental
thereto, and upon surrender and cancellation of this Warrant, if mutilated,  the
Company  will make and  deliver a new  Warrant  of like  tenor,  in lieu of this
Warrant.

8.   Elimination of Fractional Interests.
     ------------------------------------

     The  Company  shall  not be  required  to issue  certificates  representing
fractions of Shares on the exercise of this Warrant, nor shall it be required to
issue scrip or pay cash in lieu of fractional interests,  it being the intent of
the  parties  that all  fractional  interests  shall be  eliminated  pursuant to
Section 5.2.

9.   Reservation and Listing of Securities.
     --------------------------------------

     The Company shall at all times reserve and keep available out

                                       -6-

<PAGE>


of its authorized  Shares,  solely for the purpose of issuance upon the exercise
of this  Warrant,  such number of Shares as shall be issuable  upon the exercise
hereof and thereof. The Company covenants and agrees that, upon exercise of this
Warrant and payment of the Purchase  Price  therefor,  all Shares  issuable upon
such exercise shall be duly and validly issued,  fully paid and non- assessable.
As long as  this  Warrant  shall  be  outstanding,  the  Company  shall  use its
reasonable  best efforts to cause all Shares  issuable upon the exercise of this
Warrant to be listed  (subject to official notice of issuance) on all securities
exchanges on which the Shares of the  Company's  Common Stock may then be listed
and/or quoted on NASDAQ.

10.  Notices.
     --------

     All notices, requests, consents and other communications hereunder shall be
in writing and shall be deemed to have been duly given when delivered, or mailed
by registered or certified mail, return receipt requested:

     (a) If to the  registered  Holder of this  Warrant,  to the address of such
     Holder as shown on the books of the Company; or

     (b) If to the  Company,  to the address set forth on the first page of this
     Warrant or to such other  address as the Company may designate by notice to
     the Holders.

                                       -7-
<PAGE>


11.  Successors.
     -----------

     All the covenants, agreements,  representations and warranties contained in
this  Warrant  shall  bind  the  parties  hereto  and  their  respective  heirs,
executors, administrators, distributees, successors and assigns.

12.  Headings.
     ---------

     The Article and Section  headings in this Warrant are inserted for purposes
of convenience only and shall have no substantive effect.

13.  Law Governing.
     --------------

     This  Warrant  shall be  construed  and enforced in  accordance  with,  and
governed by, the laws of the State of Florida.


                                       -8-

<PAGE>


     WITNESS the seal of the Company and the  signature  of its duly  authorized
officers.

                                                  BENTLEY PHARMACEUTICALS, INC.
[SEAL]
                                                  By /s/ James R. Murphy  
                                                     -------------------  
                                                      James R. Murphy
                                                      President & CEO

Attest:



/s/ Michael D. Price       
- --------------------       
Michael D. Price, Secretary


                                       -9-

<PAGE>


                                SUBSCRIPTION FORM

                    (To be Executed by the Registered Holder

                        in order to Exercise the Warrant)

     The undersigned hereby irrevocably elects to exercise the right to purchase
____________  Shares by this  Warrant  according  to the  conditions  hereof and
herewith makes payment of the Purchase Price of such Shares in full.


                                                    ____________________________
                                                    Signature


                                                    ____________________________
                                                    Address


Dated:_________________, 19___.                        _______________________
                                                       Social Security No. or
                                                       Taxpayer's I. D. No.

                                      -10-


                                                                     Exhibit 4.7
                                                                     -----------

Plexus Ventures, Inc.


October 15, 1996



Mr. James R. Murphy
Chief Executive Officer
Bentley Pharmaceuticals, Inc.
One Urban Centre, Suite 550
West Kennedy Boulevard
Tampa, FL 33609

Dear Jim:

     Following our recent discussions, we are pleased to present a collaboration
concept for your consideration.  Our objective in what follows is to structure a
relationship between Bentley  Pharmaceuticals and Plexus Ventures which would be
simple, flexible and effective for both parties and affordable to Bentley.

Mission

     Our mission will be to work with Bentley over a period of twelve  months to
identify  appropriate new acquisition  opportunities  for Bentley.  We will work
with you and your staff to define the  characteristics of the properties we will
help you to acquire.  In general terms, Plexus Ventures will search out products
and companies  which can contribute to Bentley sales and profits in the U.S. and
targeted European markets.  Plexus Ventures will further assist you in designing
realistic  deal  structures,  including  financing  strategy  for deals,  and in
negotiating and closing acquisitions.

     Bentley and Plexus envision the term of this agreement to extend for twelve
(12) months from the date of acceptance by Bentley;  however, both parties agree
to a review of the relationship after six (6) months time, at which point either
party may terminate the agreement.

Compensation

     Typically,  Plexus Ventures receives  compensation in the form of a monthly
retainer  plus success fees paid on completion of  assignment.  Retainers  range
from $5,000.00 per month and small amounts of equity to $15,000.00 per month, no
equity.

     For this project,  we propose that Bentley  grants Plexus  Ventures  30,000
common shares which we will earn at the rate of 2,500 shares per month during


<PAGE>


a 12-month  commitment by a 12-month commitment by Bentley. At the current value
of the stock, this would be equivalent to a retainer of some $8,000/month.

Success Fees

     We  propose  that at this point we merely  agree that a success  fee of the
Lehman type (5% on the initial  tranche of value, 4% on the next higher tranche,
etc.)  will  be paid to  Plexus  Ventures  on each  completed  deal.  Since  any
contemplated  deal  will  likely  require  non-conventional   financing,  it  is
difficult to suggest a universal  formula a priori. We are more attracted to the
idea of agreeing on a  structure,  deal by deal,  as soon as we can perceive the
outlines of the transaction.

     Plexus  Ventures  would  like to have the  option to take  success  fees in
equity or in cash.

Expenses

     We propose to bill  Bentley  $9,000 each six months for recovery of general
overheads.   In  addition,   project  related  out-of-pocket  expenses  will  be
separately  recovered  from  Bentley  under  prior-approval  guidelines  set  by
Bentley.

                                     *******

     We hope  you  will  agree  that  this  approach  is  simple,  flexible  and
affordable.  If you are  interested  in  proceeding,  we will  develop  a formal
agreement for you.

     We  are   enthusiastic   about  the   prospects   of  working  for  Bentley
Pharmaceuticals;  we have  supplied a description  of our initial  target to Bob
Stote.

Sincerely,                                Accepted for Bentley Pharmaceuticals:

/s/ John F. Chappell                      /s/ James R. Murphy

John F. Chappell                          James R. Murphy
President                                 Chief Executive Officer

                                          Date: 23 Oct. 1996


                                       -2-



                                                                     Exhibit 4.8
                                                                     -----------

                               BELMAC CORPORATION
                       NONQUALIFIED STOCK OPTION CONTRACT
                       ----------------------------------


     THIS  NONQUALIFIED  STOCK OPTION  CONTRACT  entered into on this 9th day of
June, 1995, between BELMAC  CORPORATION,  a Florida corporation (the "Company"),
and RANALD STEWART, JR. (the "Optionee").


                              W I T N E S S E T H :
                              - - - - - - - - - -
   
1. The Company hereby grants, as of the date hereof, to the Optionee, subject to
the terms and  conditions  of the 1991 Stock Option Plan (the  "Plan")  attached
hereto,  but not  granted  pursuant to such Plan,  options  (the  "Options")  to
purchase an  aggregate  of 40,000  post-split  shares of the Common Stock of the
Company,  par value $.02 per share (the  "Common  Stock").  Options to  purchase
20,000  post-split  shares of Common Stock shall be exercisable at a price equal
to $5.625 per share and shall expire on December  29, 2004;  Options to purchase
the remaining  20,000 post- split shares of Common Stock shall be exercisable at
a price  equal to  $20.00  per share and  shall  expire on June 9,  2004.  These
Options shall not be treated as "incentive  stock  options" under Section 422 of
the Internal Revenue Code.

2. The Options granted hereby are subject to the acknowledgment and agreement by
the Optionee that the options granted by the Company to the Optionee pursuant to
stock option contracts dated December 29, 1994 and August 5, 1993 to purchase an
aggregate of 400,000 pre-split shares of Common Stock have expired  unexercised.
Such  acknowledgment  and agreement  shall be evidenced by the execution of this
Contract by the Optionee.

3. The term of these Options shall be as stated in the first  paragraph  hereof,
subject to earlier  termination as provided in the Plan.  These Options shall be
immediately  exercisable.  Notwithstanding the foregoing, the Options may not be
exercised  at any time in an amount less than 100 shares of Common Stock (or the
remaining  shares of Common  Stock  then  covered by and  purchasable  under the
Options  if less than 100) and in no event may a  fraction  of a share of Common
Stock be purchased under these Options.

4. These Options shall be exercised by giving  written  notice to the Company at
its principal office,  presently 4830 West Kennedy Boulevard,  One Urban Centre,
Suite 548, Tampa, Florida 33609, Attn:  Secretary,  stating that the Optionee is
exercising these Options,  specifying the number of shares of Common Stock being
purchased and  accompanied  by payment in full of the aggregate  purchase  price
therefor (a) in cash or by certified check, (b) with previously  acquired shares
of Common Stock or (c) a combination of the foregoing.

5. Notwithstanding the foregoing,  these Options shall not be exercisable by the
Optionee  unless (a) a registration  statement under the Securities Act of 1933,
as amended (the "Securities  Act") with respect to the shares of Common Stock to
be received  upon the exercise of the Options

<PAGE>



shall be  effective  and  current  at the time of  exercise  or (b)  there is an
exemption  from  registration  under the  Securities Act for the issuance of the
shares of  Common  Stock  upon  exercise.  At the  request  of the Stock  Option
Committee  (the  "Committee"),  the  Optionee  shall  execute and deliver to the
Company his representation and warranty,  in form and substance  satisfactory to
the Committee, that the shares of Common Stock to be issued upon the exercise of
the  Options  are  being  acquired  by the  Optionee  for his own  account,  for
investment  only and not with a view to the resale or distribution  thereof.  In
addition, the Committee may require the Optionee to represent and warrant to the
Company in  writing  that any  subsequent  resale or  distribution  of shares of
Common Stock by him will be made only pursuant to (i) a  Registration  Statement
under the  Securities  Act which is  effective  and current  with respect to the
shares of  Common  Stock  being  sold,  or (ii) a  specific  exemption  from the
registration requirements of the Securities Act, but in claiming such exemption,
the  Optionee  shall prior to any offer of sale or sale of such shares of Common
Stock provide the Company with a favorable  written opinion of counsel,  in form
and  substance  satisfactory  to the Company,  as to the  applicability  of such
exemption to the proposed sale or distribution.

6. Notwithstanding anything herein to the contrary, if at any time the Committee
shall  determine  in its  discretion  that the listing or  qualification  of the
shares of Common Stock  subject to these Options on any  securities  exchange or
under any  applicable  law,  or the  consent  or  approval  of any  governmental
regulatory  body,  is necessary or desirable as a condition of, or in connection
with,  the  granting  of an  option,  or the issue of  shares  of  Common  Stock
thereunder,  these  Options may not be exercised in whole or in part unless such
listing, qualification, consent or approval shall have been effected or obtained
free of any conditions not acceptable to the Committee.

7. The Company may affix appropriate legends upon the certificates for shares of
Common  Stock  issued upon  exercise  of these  Options and may issue such "stop
transfer" instructions to its transfer agent in respect of such shares of Common
Stock as it determines, in its discretion, to be necessary or appropriate to (a)
comply  with  the  registration  requirements  of  the  Securities  Act,  or (b)
implement the  provisions  of the Plan or any agreement  between the Company and
the Optionee with respect to such shares of Common Stock.

8. As provided  in the Plan,  the Company  may  withhold  cash and/or  shares of
Common Stock in the amount necessary to satisfy its obligation to withhold taxes
or require the  Optionee to pay the Company  such amount in cash  promptly  upon
demand.

9. The  Company  and the  Optionee  agree  that they will both be subject to and
bound by all the terms and  conditions  of the Plan, a copy of which is attached
hereto and made a part hereof, provided,  however, that the provisions contained
in the Plan  respecting  exercisability  in the event of the  Optionee's  death,
disability or retirement  (as defined in the Plan),  shall not be applicable and
the Options shall remain exercisable for the duration of their term.

10. The Optionee  represents  and agrees that he will comply with all applicable
laws  relating  to the Plan and the grant and  exercise  of the  Options and the
disposition of the shares of Common 

                                      -2-
<PAGE>


Stock  acquired  upon  exercise of the Options,  including  without  limitation,
federal and state securities and "blue sky" laws.

11. These  Options are not  transferable  otherwise  than by will or the laws of
descent  and  distribution  and may be  exercised,  during the  lifetime  of the
Optionee, only by him or his legal representatives.

12.  This  Contract  shall be  binding  upon and  inure  to the  benefit  of any
successor  or assign of the  Company  and to any  heir,  distributee,  executor,
administrator or legal  representative  entitled by law to the Optionee's rights
hereunder.

13. This Contract shall be governed by and construed in accordance with the laws
of the State of Florida.

14. The  invalidity or  illegality of any provision  herein shall not affect the
validity of any other provision.


     IN WITNESS  WHEREOF,  the parties hereto have executed this Contract on the
day and year first above written.

                                         BELMAC CORPORATION

                                         By:  /s/ Michael D. Price
                                              --------------------
                                              Michael D. Price, Vice President
                                              and Chief Financial Officer

ACKNOWLEDGED AND AGREED:



/s/ Ranald Stewart
- ------------------
Ranald Stewart, Jr.

                                      -3-





                         RONALD TRAHAN ASSOCIATES, INC.
                            PUBLIC RELATIONS COUNSEL

                                                                   EXHIBIT 4.9
                                                                   -----------

                                                                  May 13, 1996
Mr. James R. Murphy
Chief Executive Officer
Bentley Pharmaceuticals, Inc.
One Urban Centre, Suite 550
4830 West Kennedy Boulevard
Tampa, FL 33609-2517

Dear Jim:

This  "letter of  agreement,"  effective  May 16,  1996,  outlines the terms and
conditions  under  which  my firm  ("RTA")  would  be most  pleased  to serve as
investor  relations/public  relations  counsel to Bentley  Pharmaceuticals  Inc.
("BTN").

o Length of agreement:  12 months,  renewable on May 1, 1997,  unless terminated
earlier under termination clause contained herein;

o Scope of  services:  RTA will  provide a wide range of services as  necessary,
including counsel,  written materials,  presentation and interview coaching, and
media and investor relations;

o Payment Terms: An invoice for services  rendered and expenses incurred will be
issued to Bentley  Pharmaceuticals  on the first  business  day of each month of
service. BTN agrees to pay each invoice, in full, and deliver the payment to RTA
no later than the last business day of the month in which the invoice is due and
payable;  the first  invoice under this  agreement  will be delivered to Bentley
Pharmaceuticals  on May  16,  for  the  period  May  16-May  31,  which  will be
considered "full" work month for purposes of this agreement; RTA will expect the
first payment  under this  agreement to be delivered no later than May 31, which
is the last business day of the month;

o Monthly  retainer/Stock  options:  Bentley  Pharmaceuticals  agrees to pay RTA
$4,000 each month for the length of this  contract,  which  commences on May 16,
1996. Additionally,  Bentley Pharmaceuticals agrees to give Ronald C. Trahan the
option to purchase 25,000 shares of the company's  stock, at a "locked in" price
per  share as of the  close of  business  of May 16;  these  options  will  vest
quarterly, at the rate of 6,250 shares;

o Reimbursement: Bentley Pharmaceuticals agrees to reimburse RTA for any and all
reasonable out-of-pocket expenditures -- such as telephone, travel, photocopying
and  postage  expenses  -- that RTA may  incur  in the  role of  investor/public
relations counsel for BTN. Sizable  production-related  expenditures will not be
incurred without the company's prior approval;

                 One Apple Hill o Suite 316 o Natick, MA o 01760
                   Phone (508) 651-1180 o Fax: (508) 651-1556


<PAGE>


                                                           LETTER OF AGREEMENT/2

o  Indemnification:  Bentley  Pharmaceuticals  agrees to indemnify  and hold RTA
harmless  from and  against  any and all losses,  claims,  damages,  expenses or
liabilities that RTA incurs as the result of any  information,  representations,
reports or data furnished by, prepared by or approved by Bentley Pharmaceuticals
for use by RTA;

o Termination:  This  agreement  will commence on May 16, 1996.  Either you or I
have the right to end our  relationship  by providing 60 days  advanced  written
notice of the intent to terminate.  All  indemnification  provisions  for events
occurring prior to termination will survive any such termination.

Jim, please indicate your acceptance on behalf of Bentley Pharmaceuticals of the
terms and conditions of this agreement by signing and returning it to me at your
earliest convenience.

Thank you very much for your  business!  I look  forward to a long and  mutually
beneficial relationship.

Sincerely,



/s/ Ronald C. Trahan
- --------------------
Ronald C. Rahan
President
Ronald Trahan Associates Inc.

Accepted by:



/s/ Michael D. Price
- --------------------
Michael D. Price
VP, CFO
Bentley Pharmaceuticals, Inc.


                                       -2-












                                  June 2, 1997



Bentley Pharmaceuticals, Inc.
4830 West Kennedy Boulevard
One Urban Centre, Suite 548
Tampa, Florida 33609

                        Re:  Bentley Pharmaceuticals, Inc.
                             -----------------------------

Dear Sir or Madam:

            We have  acted as  counsel to  Bentley  Pharmaceuticals,  Inc.  (the
"Company") in connection with its filing of a registration statement on Form S-3
(the "Registration  Statement")  relating to an aggregate of 2,103,150 shares of
Common Stock,  par value $.02 per share,  of the Company,  to be sold by certain
selling   stockholders  (the  "Selling   Stockholder   Shares"),   all  as  more
particularly described in the Registration Statement.

            In our  capacity as counsel to the  Company,  we have  examined  the
Company's Amended and Restated Articles of Incorporation and By-laws, as amended
to date, and the minutes and other  corporate  proceedings  of the Company,  the
Registration Statement and the exhibits thereto.

            With respect to factual matters,  we have relied upon statements and
certificates  of  officers  of the  Company.  We have also  reviewed  such other
matters of law and  examined and relied upon such other  documents,  records and
certificates as we have deemed relevant hereto. In all such examinations we have
assumed conformity with the original documents of all documents  submitted to us
as conformed or photostatic  copies, the authenticity of all documents submitted
to us as  originals  and the  genuineness  of all  signatures  on all  documents
submitted to us.


<PAGE>


Bentley Pharmaceuticals, Inc.
June 2, 1997
Page -2-

            On the  basis  of the  foregoing,  we are of the  opinion  that  the
Selling  Stockholder  Shares have been validly authorized and legally issued and
are fully-paid and non-assessable.

            We hereby consent to the filing of this opinion as an exhibit to the
Registration  Statement and to the reference made to us under the caption "Legal
Matters" in the prospectus constituting part of the Registration Statement.

                                        Very truly yours,

                                        /s/ Parker Chapin Flattau & Klimpl, LLP

                                        PARKER CHAPIN FLATTAU & KLIMPL, LLP





                                                                    Exhibit 23.1
                                                                    ------------






INDEPENDENT AUDITORS' CONSENT

We consent to the incorporation by reference in this  Registration  Statement of
Bentley  Pharmaceuticals,  Inc. on Form S-3 of our reports  dated March 27, 1997
appearing  in the Annual  Report on Form 10-K of the  Company for the year ended
December 31, 1996 and to the reference to us under the heading  "Experts" in the
Prospectus, which is part of such Registration Statement.



/s/ Deloitte & Touche LLP
DELOITTE & TOUCHE LLP
Tampa, Florida
June 2, 1997





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