BENTLEY PHARMACEUTICALS INC
S-3, 1999-06-15
PHARMACEUTICAL PREPARATIONS
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      As filed with the Securities and Exchange Commission on June 15, 1999

                                               Registration No. 333-____________
- --------------------------------------------------------------------------------
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                        --------------------------------
                                    FORM S-3
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933
                        --------------------------------
                          BENTLEY PHARMACEUTICALS, INC.
             (Exact Name of Registrant as Specified in its Charter)

          Florida                                           59-1513162
(State or Other Jurisdiction                             (I.R.S. Employer
     of Incorporation                                   Identification No.)
      or Organization)
                                                     Mr. James R. Murphy
                                                 Bentley Pharmaceuticals, Inc.
     65 Lafayette Road                               65 Lafayette Road
  North Hampton, NH 03862                         North Hampton, NH 03862
      (603) 964-8006                                  (603) 964-8006


(Address, Including Zip Code, and             Name, Address, Including Zip Code,
   Telephone Number Including                  and Telephone Number, Including
Area Code, of Registrant's Principal           Area Code, of Agent For Service)
       Executive Offices)
                          ---------------------------
                                    Copy to:

                              Mark S. Hirsch, Esq.
                             Jordan A. Horvath, Esq.
                       Parker Chapin Flattau & Klimpl, LLP
                           1211 Avenue of the Americas
                            New York, New York 10036
                          ---------------------------
      Approximate date of commencement of proposed sale to the public: From time
to time after this Registration  Statement becomes  effective,  as determined by
market conditions.
      If the only  securities  being  registered  on this form are being offered
pursuant to dividend or interest  reinvestment plans, please check the following
box. [ ]
      If any of the securities  being  registered on this form are to be offered
on a delayed or continuous  basis  pursuant to Rule 415 under the Securities Act
of 1933,  other than  securities  offered only in  connection  with  dividend or
interest reinvestment plans, check the following box. [X]
      If this Form is filed to register  additional  securities  for an offering
pursuant to Rule 462(b) under the Securities Act, please check the following box
and list  the  Securities  Act  registration  statement  number  of the  earlier
effective registration statement for the same offering. [ ]_____________________
      If this Form is a  post-effective  amendment filed pursuant to rule 462(c)
under the  Securities  Act,  check the following box and list the Securities Act
registration  statement number of the earlier effective  registration  statement
for the same offering. [ ]
      If delivery of the prospectus is expected to be made pursuant to Rule 434,
please check the following box. [ ]
<TABLE>
<CAPTION>
                                                  CALCULATION OF REGISTRATION FEE
===================================================================================================================================
<S>                                    <C>                  <C>                       <C>                       <C>
                                       |                     |     Proposed     |         Proposed          |
                                       |                     |      Maximum     |          Maximum          |      Amount Of
            Title of Shares            |      Amount To      |  Aggregate Price |        Aggregate          |    Registration
           To Be Registered            |    Be Registered    |   Per Share (1)  |    Offering Price (1)     |         Fee
- ---------------------------------------|---------------------|------------------|---------------------------|----------------------
common stock, $.02 par value per share |   2,002,489 shares  |     $3.28125     |       $6,570,667          |       $1,827
=======================================|=====================| =================|========================== |======================
</TABLE>
     (1)   Estimated  solely for the purpose of calculating the registration fee
           pursuant to Rule 457 of the Securities Act of 1933 as amended,  based
           on the average of the high ($3.375) and low ($3.1875)  reported sales
           prices on the American Stock Exchange on June 9, 1999.

           The Registrant hereby amends this Registration Statement on such date
or dates as may be necessary to delay its  effective  date until the  Registrant
shall file a further amendment which specifically  states that this Registration
Statement shall  thereafter  become effective in accordance with Section 8(a) of
the Securities  Act of 1933 or until this  Registration  Statement  shall become
effective on such date as the  Commission,  acting pursuant to Section 8(a), may
determine.
<PAGE>

The  information in this  prospectus is not complete and may be changed.  We may
not sell  these  securities  until the  registration  statement  filed  with the
Securities and Exchange Commission is effective. This prospectus is not an offer
to sell these  securities and is not seeking an offer to buy these securities in
any state where the offer or sale is not permitted.

                    SUBJECT TO COMPLETION DATED JUNE 15, 1999


                                   PROSPECTUS



                          BENTLEY PHARMACEUTICALS, INC.

                        2,002,489 shares of common stock


         o        The  shares of common  stock  offered by this  prospectus  are
                  being  sold  by  the   selling   stockholders.   The   selling
                  stockholders  may offer their shares through public or private
                  transactions,  at  prevailing  market  prices or at  privately
                  negotiated prices.

         o        We will not receive any  proceeds  from the  exercise of these
                  shares. We will receive proceeds from the exercise of warrants
                  and those will be used for our general corporate purposes.

                             ------------------------------
                            |American Stock Exchange       |
                            |Pacific Exchange, Inc.        |
                            |Symbol for common stock: "BNT"|
                             ------------------------------

         o        On June 9, 1999,  the closing bid price of our common stock on
                  the American Stock Exchange was $3.25 per share.

         The  securities  offered in this  prospectus  involve a high  degree of
         risk. You should  carefully  consider the factors  described  under the
         heading "Risk Factors" beginning on page 3 of this prospectus.


         Neither the Securities and Exchange Commission nor any state securities
         commission has approved or disapproved these securities,  or determined
         if this prospectus is truthful or complete.  Any  representation to the
         contrary is a criminal offense.


                 The date of the Prospectus is June ____ , 1999

<PAGE>

                                Table of Contents



RISK FACTORS................................................................3

USE OF PROCEEDS............................................................12

SELLING STOCKHOLDERS.......................................................13

PLAN OF DISTRIBUTION.......................................................15

WHERE YOU CAN FIND MORE INFORMATION ABOUT US...............................16

INDEMNIFICATION OF DIRECTORS AND OFFICERS..................................17

LEGAL MATTERS..............................................................17

EXPERTS  ..................................................................17



                                       -2-

<PAGE>

                                  RISK FACTORS

         Before  you buy shares of our  common  stock,  you should be aware that
there are various risks associated with such purchase, including those described
below.  You should consider  carefully these risk factors,  together with all of
the other information in this Prospectus, and the documents we have incorporated
by  reference  in the  section  "Where You Can Find More  Information  About Us"
before you decide to purchase shares of our common stock.

         Some of the information in this Prospectus and in the documents we have
incorporated  by  reference  may  contain   forward-looking   statements.   Such
statements can be generally identified by the use of forward-looking  words such
as "may," "will,"  "expect,"  "anticipate,"  "intend,"  "estimate,"  "continue,"
"believe," or other similar words. These statements discuss future expectations,
or state other "forward-looking"  information. When considering such statements,
you should keep in mind the risk factors and other cautionary statements in this
Prospectus.  The risk factors  noted in this section and other  factors noted in
this Prospectus  could cause our actual results to differ  materially from those
contained in any forward-looking statements.

                Risks associated with our past financial results

We could be required to cut back or stop operations if we are unable to raise or
obtain needed funding

         We are  experiencing  losses from  operations  resulting in the need to
fund our operations through outside financing.  In October 1995 we completed two
private  placements  resulting  in net  proceeds  to  Bentley  of  approximately
$1,590,000,  all of which was used to fund our working capital.  The 1996 Public
Offering resulted in proceeds of approximately $5,700,000.  Most of the proceeds
of the 1996 Public  Offering was used to repay the debt  incurred in the private
placements.   We  also  received   approximately   $9,800,000   in  1997,   when
approximately 70% of our then outstanding  Class A Warrants were exercised.  The
Class  A  Warrants  originally  were  sold as a  component  of the  1996  Public
Offering.  Our future existence and profitability depends on our ability to fund
and expand operations in an effort to achieve profits from operations. We cannot
assure you that our business will ultimately generate sufficient revenue to fund
our operations on a continuing basis.

         Although we were founded in 1974, we have only  generated  revenue from
product-related  sales  since  August  1991.  We have  used  cash  from  outside
financing to fund our operations. We have made progress toward commercialization
of  specific  products  and  have  began  to  commercialize  others.  We are now
generating  revenues  from sales of  products  by our  subsidiary,  Laboratorios
Belmac,  S.A.,  a  pharmaceutical  manufacturer  located in Spain.  We  acquired
Laboratorios Belmac in February 1992.  Substantial amounts of time and financial
and other  resources will be required to complete the  development  and clinical
testing of our products currently under development. Due to our limited cash, we
suspended most of our research and development  activities pending the selection
of strategic  partners for development and marketing.  We cannot assure you that
we  will  receive   additional   funding  necessary  to  continue  research  and
development  activities  or that we will  otherwise  succeed in  developing  any
additional products with commercially valuable applications.

         We believe  that with our  emphasis on product  distribution  in Spain,
strategic alliances and product acquisitions together with careful management of
our  research and  development  activities  and the net  proceeds  from the 1996
Public  Offering,  that we  should  have  sufficient  liquidity  to enable us to
conduct our


                                       -3-

<PAGE>

existing  operations  into the year 2000,  of which  there can be no  assurance.
However,  our  pharmaceutical  products  being  developed,   and  which  may  be
developed, will require the investment of substantial additional time as well as
financial  and  other  resources  in order to  become  commercially  successful.
Following the development  period, our products will generally be required to go
through lengthy  governmental  approval processes,  including extensive clinical
testing,  followed by educating physicians,  pharmacists and consumers about the
benefits of our product and  developing a market for our product.  Revenues from
our  operations  and cash may not be sufficient  over the next several years for
commercializing any of the products we are currently  developing.  Consequently,
we may require additional licensees or partners and/or additional financing.  We
cannot assure you that we can conclude such  commercial  arrangements  or obtain
additional capital when needed on acceptable terms, if at all.

         At December 31, 1998,  we had net  operating  loss  carryforwards  (the
"NOLs") of  approximately  $29,000,000  available to offset future U.S.  taxable
income.  NOLs are losses  reflected  on tax  returns  that we can use to off-set
future U.S. taxable income, subject to various legal restrictions.

We have a history of losses and if we do not achieve profitability we may not be
able to continue our business in the future

         As of March 31, 1999 we have accumulated losses  (accumulated  deficit)
of approximately $74,405,000. We anticipate incurring additional losses until we
can successfully market and distribute our products and develop new technologies
and  commercially  viable  future  products.  If we are unable to do so, we will
continue to have losses and might not be able to continue our operations.

         We have incurred the following losses since 1996:

         Fiscal year ended:
                  o        December 31, 1996 ............... $2,919,000
                  o        December 31, 1997 ............... $3,815,000
                  o        December 31, 1998 ............... $2,876,000

         Quarter ended:
                  o        March 31, 1999 .....................$547,000

We may be restricted  from using our net operating loss  carryforwards  due to a
change in equity ownership and a change in our tax year

         As of  December  31,  1998,  we had NOLs of  approximately  $29,000,000
available to offset future U.S.  taxable  income.  The use of the NOLs generated
through December 31, 1997 may be limited to  approximately  $1,000,000 each year
as a result of stock,  option and warrant  issuances  resulting  in an ownership
change  of more than 50% of our  outstanding  equity.  The NOL of  approximately
$3,200,000 generated during the tax year ended December 31, 1998 is available to
offset future  taxable income without  limitation.  Additionally,  approximately
$1,800,000 of the NOL generated in 1995 available to offset future U.S.  taxable
income  will be limited  to  approximately  $300,000  per year over the next six
years  due to the  change in tax year end  during  1995.  We used  approximately
$14,000,000  of NOLs to offset taxable income during 1997. If not offset against
future  taxable  income,  the NOL  carryforwards  will  expire in tax years 2007
through 2013.

                                       -4-

<PAGE>

                       Risks associated with our business

Successful development of current and future products is uncertain

         We recently purchased  technology to enhance the penetration of certain
pharmaceutical  products through the dermal layers of the skin. Although several
systems have been developed by various  pharmaceutical  companies to enhance the
transdermal  delivery of specific drugs,  relatively  limited  research has been
conducted in the expansion of transdermal  delivery  systems to a wider range of
pharmaceutical products. Transdermal delivery systems are currently marketed for
only a limited number of products.  In addition,  transdermal  delivery  systems
used to date have often  demonstrated  adverse side  effects for users,  such as
skin irritation and delivery difficulties.

         Our  proposed  products  are in the early  development  stage,  require
significant  further  development,  testing and  regulatory  clearances  and are
subject to the risks of failure inherent in the development of products based on
innovative  technologies.  Due to our limited  resources,  collaboration will be
essential  in order  to  complete  the  development  of  specific  products.  No
assurance can be given that the necessary collaboration will be obtained.  Risks
during  development  include the  possibilities  that any or all of the proposed
products  may be found to be  ineffective  or toxic,  or  otherwise  may fail to
receive necessary regulatory  clearances;  that the proposed products,  although
effective,  may be  uneconomical  to market;  or that third  parties  may market
superior or  equivalent  products.  Due to the extended  testing and  regulatory
review process  required before marketing  clearance can be obtained,  we do not
expect to be able to realize royalty  revenues from the sale of any drugs in the
near term.

Clinical trial results may result in failure to obtain  regulatory  approval and
inability to sell products

         Before approving a drug for commercial sale as treatment for a disease,
the FDA and other regulatory  authorities  generally require that the safety and
efficacy of a drug be  demonstrated  in humans.  If our  clinical  trials do not
demonstrate  the safety or efficacy of our products,  or if we otherwise fail to
obtain  regulatory  approval for our  products,  we will not be able to generate
revenues  from the  commercial  sale of our products.  Any human  pharmaceutical
product  developed by us would require  clearance by Spain's  Ministry of Health
for sales in Spain, the U.S. Food and Drug  Administration  ("FDA") for sales in
the United  States and  similar  agencies  in other  countries.  The  process of
obtaining  these  approvals  is costly and  time-consuming,  and there can be no
assurance  that  such  approvals  will  be  granted.  In  general,  only a small
percentage of new  pharmaceutical  products  achieve  commercial  success.  Such
governmental  regulation may prevent or substantially delay the marketing of our
products and may cause us to  undertake  costly  procedures  with respect to our
research and development  and clinical  testing  operations  which may furnish a
competitive advantage to more substantially  capitalized companies which compete
with Bentley. In addition,  we are required,  in connection with our activities,
to comply with good manufacturing  practices (GMPs) and local, state and federal
regulations. Non-compliance with these regulations could have a material adverse
effect on Bentley and/or prevent the commercialization of our products.

Our patent  position is  uncertain  and our success  depends on our  proprietary
rights

         We have filed  numerous  patent  applications  and have been  granted a
number  of  patents.  However,  there  can  be no  assurance  that  our  pending
applications  will be issued as patents or that any of our issued  patents  will
afford  adequate  protection  to us or our  licensees.  Other private and public
entities have also filed applications for, or have been issued,  patents and are
expected to obtain patents and other proprietary rights

                                       -5-

<PAGE>

to technology which may be harmful to the  commercialization of our products. We
cannot  determine the ultimate scope and validity of patents which are now owned
by or may be granted to third parties in the future,  the extent to which we may
wish or be  required  to  acquire  rights  under  such  patents,  or the cost or
availability of such rights. In addition, we also rely on unpatented proprietary
technology in the development and commercialization of our products. There is no
assurance  that  others  may not  independently  develop  the  same  or  similar
technology or obtain access to our proprietary technology.

         We also rely upon trade secrets,  unpatented  proprietary  know-how and
continuing technological innovations to develop our competitive position. All of
our  employees  with access to our  proprietary  information  have  entered into
confidentiality  agreements  and have  agreed  to  assign  to us any  inventions
relating to our business made by them while in our employ. However, there can be
no  assurance  that  others may not  acquire or  independently  develop  similar
technology or, if patents in all major  countries are not issued with respect to
our  products,  that we will be able to maintain  information  pertinent to such
research as proprietary technology or trade secrets.

We may have to lower prices or spend more money to effectively  compete  against
companies  with greater  resources  than us which could result in lower revenues
and/or profits

         We compete with other pharmaceutical companies, biotechnology firms and
chemical  companies,   many  of  which  have  substantially  greater  financial,
marketing  and  human  resources  than  us  (including   substantially   greater
experience  in clinical  testing,  production  and  marketing of  pharmaceutical
products).  We cannot  assure you that we will be able to  compete  successfully
given these factors.  For example,  if our  competitors  offer lower prices,  we
could be forced to lower  prices  which  would  result in reduced  margins and a
decrease in  revenues.  If we do not lower prices we could lose sales and market
share.  In either case,  if we are unable to compete  against  companies who can
afford to cut prices,  we would not be able to generate  sufficient  revenues to
grow Bentley or reverse our history of losses. We also experience competition in
the  development  of our  products and  processes  from  individual  scientists,
hospitals,  universities and other research institutions and, in some instances,
compete with others in acquiring technology from these sources.

Rapid  technological  change may result in our products becoming obsolete before
we recoup a significant portion of related costs

         The  pharmaceutical   industry  has  undergone  rapid  and  significant
technological  change.  We expect the technology to continue to develop rapidly,
and  our  success  will  depend  significantly  on our  ability  to  maintain  a
competitive position. We have recently shifted our strategic focus so that we do
not rely on research and  development of  pharmaceuticals  from concept  through
marketing. Instead, we seek to acquire late-stage development compounds that can
be marketed within approximately one year and currently-marketed products. Rapid
technological  development  may  result  in  actual  and  proposed  products  or
processes  becoming  obsolete before we recoup a significant  portion of related
research and development, acquisition and commercialization costs.

Pharmaceutical  pricing is uncertain and may result in a negative  effect on our
profitability

         Our levels of revenues and profitability may be negatively  affected by
the  continuing  efforts of  governmental  and third party  payers to contain or
reduce the costs of health care through various means.  For example,  in certain
foreign  markets,  including  Spain,  pricing or  profitability  of prescription
pharmaceuticals is subject to government  control.  In the United States,  there
have been, and we expect that there will continue

                                       -6-

<PAGE>

to be, a number of federal and state proposals to implement  similar  government
control.  While we cannot  predict  whether any such  legislative  or regulatory
proposals will be adopted,  the adoption of such proposals could have a material
adverse  effect on our  business,  financial  condition  and  profitability.  In
addition,  sales of  prescription  pharmaceuticals  are dependent in part on the
availability of reimbursement  to the consumer from third party payers,  such as
government  and private  insurance  plans.  Third party payers are  increasingly
challenging the prices charged for medical products and services.  If we succeed
in bringing one or more products to the market,  there can be no assurance  that
these products will be considered cost effective and that  reimbursement  to the
consumer  will be  available  or will be  sufficient  to  allow  us to sell  our
products on a competitive basis.

We depend on third parties for commercialization in the United States

         We intend to sell our products in the United States and internationally
in  collaboration  with  one or more  marketing  partners.  We do not  presently
possess the resources or experience necessary to market our products in the U.S.
We presently  have no  agreements  for the licensing or marketing of our product
candidates, and we cannot assure you that we will be able to enter into any such
agreements in a timely manner or on  commercially  favorable  terms,  if at all.
Development  of  an  effective  sales  force  requires   significant   financial
resources,  time and  expertise.  We cannot  assure  you that we will be able to
obtain the financing necessary or to establish such a sales force in a timely or
cost effective  manner, if at all, or that such a sales force will be capable of
generating demand for our product candidates.

As a producer of "Orphan  Drugs" we may be required  to continue  producing  the
product regardless of its potential

         An Orphan Drug is a product or products used to treat a rare disease or
condition,  which, as defined under United States law, is a disease or condition
that affects  populations of less than 200,000  individuals  or, if victims of a
disease  number  more than  200,000,  the sponsor  establishes  that it does not
realistically  anticipate  its product  sales will be  sufficient to recover its
costs.  If a product is designated an Orphan Drug,  then the sponsor is entitled
to receive certain  incentives to undertake the development and marketing of the
product.  In Spain,  Orphan Drugs are given a preference  in the  pharmaceutical
review process by Spain's Ministry of Health if it can be shown that the product
is an important  therapeutic  agent and there is unequivocal data supporting its
efficacy.  The Ministry of Health has the  authority  to require  pharmaceutical
manufacturers  to continue to produce products which are Orphan Drugs regardless
of  their  commercial  potential.   As  required  by  the  Ministry  of  Health,
Laboratorios  Belmac  currently  manufactures  and  distributes one Orphan Drug,
Anacalcit,  which  is  used  in  the  treatment  of  nephrolithiasis.  We do not
currently market any Orphan Drugs in the United States.

We depend on key personnel and must continue to attract and retain key employees

         We believe  that we have been able to attract  skilled and  experienced
management and scientific personnel. There can be no assurance, however, that we
will  continue to attract and retain  personnel  of high  caliber.  From 1992 to
1994, five individuals served as our chief executive  officer.  This instability
in our management in the past has hampered our growth.  While we believe that we
have assembled an effective management team, the loss of several individuals who
are  considered  key  management or scientific  personnel  could have an adverse
impact on Bentley.

                                       -7-

<PAGE>

We face product liability risks

         We face an inherent  business  risk of  exposure  to product  liability
claims in the event that the use of our  technology or  prospective  products is
alleged to have  resulted  in adverse  effects.  While we have  taken,  and will
continue to take, what we believe are appropriate  precautions,  there can be no
assurance that we will avoid significant liability exposure. We maintain product
liability  insurance in the amount of $5 million.  However, we cannot assure you
that this  coverage  will be  adequate  in terms and scope to  protect us in the
event of a product  liability  claim.  In connection  with our clinical  testing
activities,  we  may,  in  the  ordinary  course  of  business,  be  subject  to
substantial  claims  by, and  liability  to,  subjects  who  participate  in our
studies.

We face risks when doing business outside of the United States

         Nearly all of our  revenues  during  1997 and 1998 have been  generated
outside the United  States,  from our  subsidiary  in Spain.  There are risks in
operations outside the United States, including, among others, the difficulty of
administering  businesses abroad,  exposure to foreign currency fluctuations and
devaluations or restrictions on money supplies,  foreign and domestic export law
and  regulations,  taxation,  tariffs,  import quotas and restrictions and other
political and economic  events beyond our control.  We have not  experienced any
material  effects of these risks as of yet,  however  there can be no  assurance
that they will not have such an effect in the future.

Our  computer  systems  may not  recognize  the year 2000  which may  affect our
computer systems and disrupt our business

         The  concerns  about the  upcoming  year 2000 have arisen  because many
existing  computer programs use only the last two digits of any particular year,
rather than all four digits,  to identify that year. These computer programs can
not properly  distinguish  between the years 1900 and 2000 or 1901 and 2001, for
example.  If not  corrected,  many  computer  applications  could fail or create
erroneous  results.  The Year  2000  issue  can  affect  information  as well as
non-information  technology  systems.  The extent of the potential impact of the
Year 2000 issue is not yet known, and if not timely corrected,  could affect the
global economy.

         We have recognized the need to ensure that our business operations will
not be  adversely  impacted  by the Year  2000  issue  and are aware of the time
sensitive nature of this problem.  As a result,  we have completed an assessment
of how we may be impacted by the Year 2000 issue.  We have  engaged  information
system  consultants  to  evaluate  our systems and  technology.  Our  assessment
process  included  a  review  of our  information  as  well  as  non-information
technology  systems.  We  have  also  considered  the  potential  impact  on our
operations  and business model in the event that third parties with whom we have
material  relationships  fail to resolve their own Year 2000 issues. The results
of our assessment phase indicated that certain  information  technology  systems
(hardware and software) needed  upgrading or replacing.  Our management has also
conducted a review of our  non-information  technology systems and has concluded
that it is not materially exposed to non-information technology system risks. We
have polled our significant suppliers, service providers and other third parties
with whom we have material relationships to determine the extent to which we are
vulnerable  to a failure of any such third party to  adequately  address its own
Year 2000 issue. We have received responses from 60% of such parties, and we are
following  up on those  who  have not  responded.  We have  not  identified  any
additional risks as a result of the responses received to date.

         In the  view of our  management,  not  only  is it  possible  that  our
management  may not  have  access  to vital  information,  which is used to make
management  decisions,  but the manufacturing process could even be interrupted,
due to unavailability of raw materials or inoperable equipment and/or systems if
our assessment
                                       -8-

<PAGE>

and remediation program is not successful.  We cannot guarantee that the systems
of other companies on which our systems rely will be timely converted, or that a
failure to convert by another company, or a conversion that is incompatible with
our systems,  would not have a material adverse effect on us. We have determined
that we have no exposure to contingencies related to the Year 2000 issue for the
products we have sold or anticipate selling in the future.

         The  costs of the Year  2000  project  and the date on which we plan to
complete  the  Year  2000  modifications  are  based  on our  management's  best
estimates,  which were derived utilizing  numerous  assumptions of future events
including  the  continued   availability  of  certain  resources,   third  party
modification  plans and other factors.  However,  we cannot guarantee that these
estimates will be achieved and actual results could differ materially from those
plans.  Specific factors that might cause such material differences include, but
are not limited to, the availability and cost of personnel trained in this area,
the ability to locate and  correct  all  relevant  computer  codes,  and similar
uncertainties.  Because of the importance of addressing the Year 2000 issue,  we
are developing contingency plans to address any issues that may not be corrected
by our Year 2000 project in a timely manner.  Our contingency  plans may include
stock  piling of raw  materials,  producing  greater than normal  quantities  of
finished goods, and implementing manual back-up systems where appropriate.

                                       -9-

<PAGE>
                      Risks associated with our securities

Your percentage of ownership, voting power and price of Bentley common stock may
decrease  as a result  of  events  which  increase  the  number of shares of our
outstanding common stock

          As of June 9, 1999, we had the following capital structure:

          Common stock outstanding assuming conversion/exercise of all
                             outstanding securities
- --------------------------------------------------------------------------------
Common stock now outstanding:                                        8,443,184
Common stock issuable upon:
         Exercise of Class A warrants:                               2,110,833
         Exercise of Class B warrants:                               3,502,500
         Exercise of underwriter warrants:                             874,000
         Conversion of Debentures:                                   2,794,800
         Exercise of other warrants:                                 1,330,000
         Exercise of options:                                        1,825,856
         Other Shares issuable:                                        801,089
                                                          ----------------------
                                                  Total:            21,682,262
- --------------------------------------------------------  ----------------------

         If all of the outstanding warrants and options were exercised,  Bentley
would  receive  proceeds  of  $40,585,000.  However,  approximately  $27,918,000
represents  proceeds  which we are not likely to receive at the present  time as
the  exercise  price of certain of the  warrants  and options is higher than the
current market price of our common stock.  If all of the  debentures  were to be
converted  (including  debentures  issuable to the underwriter of Bentley's 1996
Public Offering upon exercise of the underwriter's  warrants) our long-term debt
would be reduced by  $5,700,000.  When the  801,089  shares of common  stock are
issued, it will reduce liabilities on our balance sheet by $1,188,000.

         We may conduct additional future offerings of our common stock or other
securities  with  rights to convert  the  securities  into  shares of our common
stock.

         Conversion  or  exercise  of our  outstanding  convertible  securities,
options and warrants into common stock may  significantly  and negatively affect
the market price for the common  stock as well as decrease  your  percentage  of
ownership and voting power of the common stock.

         The market price of our shares has been volatile.  In July 1995 Bentley
effected a one-for-ten reverse stock split. As recently as the second quarter of
1995, the market price of our common stock was $9.38 (giving  retroactive effect
to the reverse  stock split).  Factors such as  announcements  of  technological
innovations  or new  commercial  products  by our  competitors,  the  results of
clinical testing,  patent or proprietary  rights,  developments,  general market
conditions or other matters may have a significant impact on the market price of
the common stock.

                                      -10-

<PAGE>

Obligations in connection with underwriter warrants,  other warrants and options
may hinder our ability to obtain future financing

         We sold to the  participating  underwriter in the Public Offering,  for
nominal  consideration,  warrants to purchase up to 570 units  exercisable for a
period of four years,  commencing one year from the date of sale, at an exercise
price of $1,200 per unit.  Each unit  consists of a debenture  due  February 13,
2006 and 1,000  Class A  Warrants.  The  underwriter  of  Bentley's  1996 Public
Offering has previously exercised 110 of the underwriter's  warrants; 460 remain
unexercised. In addition to warrants issued in the Public Offering, we currently
have  outstanding  3,155,856  options and  warrants to purchase  Common Stock at
exercise  prices ranging from $1.50 to $177.50.  The holders of the  underwriter
warrants  and of the warrants and options are likely to exercise or convert them
at a time when we are able to obtain  additional  equity  capital  on terms more
favorable  than  those  provided  by  such  warrants,  options  and  underwriter
warrants.  The underwriter  warrants and certain other warrants and options also
grant to the  holders  certain  demand  registration  rights  and  "piggy  back"
registration  rights.  These obligations may hinder our ability to obtain future
financing.


Your interest in Bentley may be diluted by the issuance of preferred  stock with
greater rights than the common stock which we can sell or issue at any time

         The sale or issuance of any shares of  preferred  stock  having  rights
superior  to those of the common  stock may result in a decrease in the value or
market price of the common stock. The issuance of preferred stock could have the
effect of  delaying,  deferring  or  preventing  a change of  ownership  without
further vote or action by the  stockholders  and may adversely affect the voting
and other rights of the holders of common stock.

         Our board of directors is authorized to issue up to 2,000,000 shares of
preferred  stock.  The board  has the power to  establish  the  dividend  rates,
preferential  payments  on  our  liquidation,   voting  rights,  redemption  and
conversion terms and privileges for any series of preferred stock.


We have  not  paid  dividends  on our  Common  Stock  and do not  intend  to pay
dividends in the foreseeable future

         We have not paid  dividends on our common stock since our inception and
do not  intend  to pay any  dividends  on our  Common  Stock in the  foreseeable
future.  However,  at our annual meeting of  stockholders to be held on June 30,
1999,  our  stockholders  will be  considering a proposal to change our state of
incorporation   from  Florida  to  Delaware  and  to  adopt  a  certificate   of
incorporation  and bylaws which  conform to Delaware  law.  Delaware law differs
from  Florida law in its  treatment  of when and how a  corporation  may declare
dividends.  Delaware law provides  that a  corporation  may pay dividends out of
surplus,  out of the corporation's net profits for the preceding fiscal year, or
both,  provided that there remains in the stated capital account an amount equal
to the par value represented by all shares of the  corporation's  stock having a
distribution preference. Florida law provides that dividends may be paid, unless
after giving effect to such  distribution,  the corporation would not be able to
pay its  debts  as  they  come  due in the  usual  course  of  business,  or the
corporation's  total assets would be less than the sum of its total liabilities,
plus (unless the corporation's  articles of incorporation  permit otherwise) the
amount needed to satisfy preferential distributions.

                                      -11-

<PAGE>

Certain  laws  may make It more  difficult  or  discourage  third  parties  from
attempting to control Bentley

         The  State  of  Florida  has  enacted  legislation  that  may  deter or
frustrate  takeovers  of Florida  corporations.  The Florida  Control  Share Act
generally   provides  that  shares  acquired  in  excess  of  certain  specified
thresholds  will not possess  any voting  rights  unless such voting  rights are
approved by a majority vote of a corporation's disinterested  stockholders.  The
Florida Affiliated Transactions Act generally requires supermajority approval by
disinterested  stockholders of certain specified  transactions  between a public
corporation and holders of more than 10% of the outstanding voting shares of the
corporation  (or their  affiliates).  Florida  law also  authorizes  Bentley  to
indemnify our directors, officers, employees and agents.
We have adopted a by-law with such an indemnity.

         However,  since we plan to consolidate our U.S. operations and relocate
our corporate  headquarters to New Hampshire in the summer of 1999 and our lease
on our corporate headquarters in Florida expires in October 1999 and will not be
renewed,  our  stockholders  will no longer  enjoy  the  benefits  of  Florida's
"anti-takeover"  statute.  This  is one of  the  reasons  our  proxy  issued  in
connection  with our annual  meeting  of  stockholders  includes a proposal  for
stockholders to approve the change of our state of incorporation from Florida to
Delaware and to adopt a certificate of incorporation and bylaws which conform to
Delaware law. Delaware law contains a statutory provision intended to discourage
certain takeover attempts of Delaware corporations which are not approved by the
board  of   directors.   This   "anti-takeover"   provision   along  with  other
"anti-takeover"  provisions being included in Bentley's proposed  certificate of
incorporation and bylaws could have the effect of lessening the possibility that
our stockholders would be able to receive a premium above market value for their
shares in the event of a takeover.  These  provisions could also have an adverse
effect on the market  value of our shares of common  stock.  To the extent  that
these provisions may restrict or discourage  takeover attempts,  they may render
less likely a takeover opposed by our board and may make removal of the board or
management less likely as well.

                                 USE OF PROCEEDS

         The selling  stockholders are selling all of the shares covered by this
prospectus for their own accounts. Accordingly, we will not receive any proceeds
from the resale of the shares. We will receive proceeds from the exercise of the
selling  stockholders'  warrants and options.  If all the selling  stockholders'
warrants and options were exercised, we would receive approximately  $3,372,500.
However,  approximately  $760,000 represents proceeds which we are not likely to
receive  at  the  present  time  as  the  exercise   price  of  certain  of  the
stockholders'  warrants  and options is higher than the current  market price of
our common stock. We would use the net proceeds from the exercise of the selling
stockholders'  warrants  and options for general  corporate  purposes  including
pharmaceutical product development.

                                      -12-

<PAGE>
                              SELLING STOCKHOLDERS

         The table below lists information  regarding the selling  stockholders'
ownership  of  shares  of our  common  stock  as of  June 9,  1999.  Information
concerning the selling  stockholders may change from time to time. To the extent
that the selling  stockholders or any of its  representatives  advise us of such
changes and if required,  we will report those  changes in a supplement  to this
document.

<TABLE>
<CAPTION>

                                                                                                      Ownership
                                                        Ownership                                 After Offering if
                                                   Prior to Offering             Maximum           Maximum is Sold
                                                   -----------------            Amount to          ----------------
Selling Stockholder                                 Amount  Percent              be Sold           Amount   Percent
- -------------------                                 ------  -------              -------           ------   -------
<S>                                            <C>        <C>                  <C>               <C>       <C>
Robert M. Stote (1)                                282,866   3.31                 15,000          267,866     3.13
Walter Light (2)                                   550,594   6.26                350,000          200,594     2.28
Plexus Ventures, Inc. (3)                          166,000   1.95                 66,000          100,000     1.18
Ranald Stewart, Jr. (4)                             40,400    *                   40,000              400      *
Jeffery Harris (5)                                   6,400    *                    6,400                0      0
Dominick & Dominick (6)                            425,000   4.79                425,000                0      0
Kinexsys (7)                                        40,000    *                   40,000                0      0
Baytree Associates, Inc. (8)                        25,000    *                   25,000                0      0
Conrex Pharmaceutical Corp.(9)                     359,282   4.08                359,282                0      0
Yungtai Hsu (10)                                   675,807   7.41                675,807                0      0
</TABLE>

- ----------------------
* Less than one percent

(1)   Dr. Stote's shares include  239,166 shares of common stock which Dr. Stote
      has the right to acquire pursuant to presently  exercisable stock options,
      10,000  shares of common  stock  which Dr.  Stote has the right to acquire
      pursuant to presently  exercisable  stock  purchase  Class A warrants (the
      "Class A  Warrants"),  4,000  shares of common stock which Dr. Stote has a
      right to acquire upon conversion of the Debentures (which Class A Warrants
      and Debentures  were  purchased in the Company's  1996 public  offering of
      such securities),  and 15,000 shares of Common Stock which are issuable to
      Dr. Stote upon approval of listing of such shares with the American  Stock
      Exchange.  Dr. Stote is the Senior Vice  President,  Chief Science Officer
      and a director of Bentley.

(2)   Mr. Light's shares include  350,000 shares of common stock which Mr. Light
      has the right to acquire pursuant to stock purchase  warrants.  200,000 of
      the shares are  issuable  to Mr.  Light upon  approval  of listing of such
      shares with the American Stock Exchange.

(3)   The shares of Plexus Ventures, Inc. include 66,000 shares earned by Plexus
      Ventures,  Inc.  as  compensation  for  consulting  services  rendered  to
      Bentley.  The shares are  issuable  to Plexus  Ventures  upon  approval of
      listing of such shares with the American Stock Exchange.

(4)   Mr.  Stewart's  shares  include  40,000  shares of Common  Stock which Mr.
      Stewart has the right to acquire pursuant to stock options. The shares are
      issuable to Mr.  Stewart upon  approval of listing of such shares with the
      American Stock  Exchange.  Mr. Stewart was a former officer and a director
      of Bentley.

                                      -13-

<PAGE>

(5)   Mr.  Harris'  shares  represent  shares of Common  Stock which Mr.  Harris
      received from Mr. Stewart in partial  settlement of a judgment against Mr.
      Stewart.

(6)   The shares of Dominick & Dominick,  Inc. represent shares which it has the
      right to acquire pursuant to a warrant. The warrant was issued to Dominick
      as  compensation  pursuant to an agreement it entered into with Bentley to
      provide financial advisory  services.  The shares are issuable to Dominick
      upon approval of listing of such shares with the American Stock  Exchange.
      To date,  Dominick has not assisted  Bentley in raising funds.  Dominick's
      agreement expires on June 18, 1999.

(7)   The shares of Kinexsys  represent shares which it has the right to acquire
      pursuant to a warrant as compensation for consulting  services rendered to
      Bentley.  The shares are issuable to Kinexsys  upon approval of listing of
      such  shares  with the  American  Stock  Exchange.  From  October  1997 to
      February 1999 Kinexsys  provided  investor  relations  services and public
      relations service to Bentley.

(8)   The shares of Baytree  Associates,  Inc. represent shares which it has the
      right to acquire pursuant to a warrant as consideration for exercising, at
      the request of Bentley,  warrants it received in 1993 and 1994. The shares
      are issuable to Baytree  upon  approval of listing of such shares with the
      American  Stock  Exchange. During  early 1993 and 1994,  Baytree  provided
      financial  advisory services to Bentley and assisted us in raising private
      funds. Baytree has not advised us since 1996.

(9)   Represents  shares  of  common  stock  issued  to  Conrex   Pharmaceutical
      Corporation  in connection  with the purchase of certain  assets of Conrex
      Pharmaceutical   Corporation   by  Yungtai  Hsu.   Conrex   Pharmaceutical
      Corporation  had agreed to accept  Bentley  shares as part of the purchase
      price.  The shares are issuable to Conrex upon approval of listing of such
      shares with the American  Stock  Exchange.  Pursuant to the asset purchase
      agreement  between  Conrex and Mr. Hsu dated February 1, 1999 effective as
      of December  31,  1998,  Conrex is entitled to receive  certain  royalties
      arising  from  collaborative   efforts  between  us  and  certain  parties
      introduced to us by Conrex.

(10)  Represents  450,000  shares of common stock  issuable upon the exercise of
      warrants and 225,807 shares of common stock to be issued to Yungtai Hsu as
      part of the  purchase  price in  connection  with our  purchase of certain
      assets from Mr. Hsu. The shares are  issuable to Mr. Hsu upon  approval of
      listing of such shares with the American Stock  Exchange.  Pursuant to the
      asset purchase agreement between Mr. Hsu and us dated February 1, 1999 and
      effective  December  31,  1998,  Mr. Hsu is  entitled  to receive  certain
      royalties from the  commercialization  of any products developed by us (or
      our successors) from the assets that we purchased from Mr. Hsu.

                                      -14-

<PAGE>
                              PLAN OF DISTRIBUTION

      The selling stockholders may offer their shares of common stock at various
times in one or more of the following transactions:

         o    On any U.S.  securities  exchange on which our common stock may be
              listed at the time of such sale;

         o    In the over-the-counter market;

         o    In   transactions   other  than  on  such   exchanges  or  in  the
              over-the-counter market;

         o    In connection with short sales; or

         o    In a combination of any of the above transactions.

         The  selling  stockholders  may offer their  shares of common  stock at
prevailing market prices, at prices related to such prevailing market prices, at
negotiated prices or at fixed prices.

         The selling stockholders may use broker-dealers to sell their shares of
common stock. If this occurs,  broker-dealers  will either receive  discounts or
commission from the selling  stockholder,  or they will receive commissions from
the  purchasers  of shares of common  stock for whom they acted as agents.  Such
brokers may act as dealers by  purchasing  any and all of the shares  covered by
this  prospectus  either as agents  for  others or as  principals  for their own
accounts and reselling such securities under the prospectus.

         The selling stockholders and any broker-dealers or other persons acting
on the behalf of parties that  participate in the distribution of the shares may
be considered underwriters under the Securities Act. As such, any commissions or
profits they receive on the resale of the shares may be considered  underwriting
discounts and commissions under the Securities Act.

         As of the date of this  prospectus,  we are not aware of any agreement,
arrangement  or  understanding  between  any  broker or dealer  and the  selling
stockholders  with  respect  to the  offer  to sale  of the  shares  under  this
prospectus.  If we become aware of any agreement,  arrangement or understanding,
to the extent  required  under the  Securities  Act, we will file a supplemental
prospectus to disclose:

                  (1)      the name of any such broker-dealers;

                  (2)      the number of shares involved;

                  (3)      the price at which such shares are to be sold;

                  (4)      the  commissions  paid or  discounts  or  concessions
                           allowed to such broker-dealers, where applicable;

                  (5)      that  such   broker-dealers   did  not   conduct  any
                           investigation  to verify the  information  set out in
                           this prospectus, as supplemented; and

                  (6)      other facts material to the transaction.

                                      -15-

<PAGE>

         The  agreements  have  indemnification  provisions  between us and each
selling  stockholder whereby each selling stockholder has agreed to indemnify us
against  liabilities  under the Securities  Act, which may be based upon,  among
other things,  any untrue  statement or alleged  untrue  statement of a material
fact or any omission or alleged  omission of a material  fact. We have agreed to
bear  customary  expenses  incident  to the  registration  of the shares for the
benefit of the selling  stockholders in accordance with such  agreements,  other
than underwriting discounts and commissions directly attributable to the sale of
such securities by or on behalf of the investor.


                       WHERE YOU CAN FIND MORE INFORMATION
                                    ABOUT US

         We file annual,  quarterly and special  reports,  proxy  statements and
other  information  with the SEC.  You may read and copy any document we file at
the SEC's public  reference rooms in Washington,  DC, New York, NY, and Chicago,
IL. Please call the SEC at 1-800-SEC-0330 for further  information on the public
reference rooms. Our SEC filings are also available to the public from the SEC's
website at http://www.sec.gov.

         We have  filed a  registration  statement  on Form  S-3 with the SEC to
register  shares  of  our  common  stock.   This  prospectus  is  part  of  that
registration  statement  and, as permitted by the SEC's rules,  does not contain
all of the  information  included  in the  registration  statement.  For further
information  about  us and this  offering,  you may  refer  to the  registration
statement and its exhibits.  You can review and copy the registration  statement
and its exhibits at the public reference facilities  maintained by the SEC or on
the SEC's website described above.

         This prospectus may contain  summaries of contracts or other documents.
Because they are summaries,  they will not contain all of the  information  that
may be important to you. If you would like complete information about a contract
or  other  document,  you  should  read  the copy  filed  as an  exhibit  to the
registration statement.

         The SEC allows us to "incorporate by reference" the information we file
with them,  which means that we can  disclose  important  information  to you by
referring you to those documents. The information we incorporate by reference is
considered to be a part of this  prospectus,  and information  that we file with
the SEC at a later date will automatically update or supersede this information.
We incorporate by reference the following documents as well as any future filing
we will  make  with the SEC  under  Sections  13(a),  13(c),  14 or 15(d) of the
Securities Exchange Act of 1934:

         1. Annual  Report on Form 10-K for the fiscal year ended  December  31,
            1998;

         2. Quarterly Report on Form 10-Q for the period ended March 31, 1999;

         3. Current Report on Form 8-K dated February 26, 1999; and

         4.   Registration  Statement on Form 8-A containing the  description of
              our common stock, dated July 20, 1995.

                                      -16-

<PAGE>

         You may request a copy of these filings,  at no cost to you, by writing
or by telephoning to us at Bentley Pharmaceuticals, Inc., 65 Lafayette Road, No.
Hampton, NH 03862, Attention: Michael D. Price, Chief Financial Officer, and our
telephone number is (603) 964-8006.


                    INDEMNIFICATION OF DIRECTORS AND OFFICERS

         Section  607.0850  of  the  Florida  Business  Corporation  Act  allows
companies to indemnify their directors and officers against expenses, judgments,
fines and  amounts  paid in  settlement  under the  conditions  and  limitations
described in the law.

         Article IV of our By-laws  authorizes  us to  indemnify  our  officers,
directors  and other  agents  to the  fullest  extent  permitted  under  Section
607.0850 of the Florida Business Corporation Act.

         As discussed above, if Bentley is reincorporated  in Delaware,  Section
145 of the Delaware General  Corporation Law will govern the  indemnification of
our  directors  and  officers.  Delaware law is very similar to Florida law with
respect to indemnification of directors and officers.  Our bylaws will contain a
provision  that we,  Bentley,  will  indemnify our directors and officers to the
fullest extent permitted under Delaware law.

         We have  entered  into an  indemnification  agreement  with each of our
directors and officers.  In some cases,  the  provisions of the  indemnification
agreement may be broader than the specific indemnification  provisions contained
in our by-laws or otherwise  permitted  under Florida law. Each  indemnification
agreement may require us to indemnify an officer or director against liabilities
that may arise by reason of his status or service as an officer or director,  or
against liabilities arising from the director's willful misconduct of a culpable
nature.  We maintain a directors and officers  liability  policy with  Lexington
Insurance  Company that  contains an aggregate  limit of liability of $2,000,000
per policy year for both directors' and officers' liability coverage.

         Insofar as indemnification for liabilities arising under the Securities
Act of 1933 may be permitted to our directors,  officers and controlling persons
pursuant to these  provisions,  or otherwise,  we have been advised that, in the
opinion of the SEC, such  indemnification  is against public policy as expressed
in the Securities Act and is, therefore, unenforceable.


                                  LEGAL MATTERS

         Parker Chapin  Flattau & Klimpl LLP, New York,  New York will pass upon
the validity of the securities offered hereby.

                                     EXPERTS

         The  consolidated   financial  statements  and  the  related  financial
statement  schedule  incorporated  in this  Prospectus  by  reference  from  the
Company's  Annual Report on Form 10-K for the year ended  December 31, 1998 have
been audited by Deloitte & Touche LLP, independent  auditors, as stated in their
reports,  which  are  incorporated  herein  by  reference,   and  have  been  so
incorporated  in reliance upon the reports given upon their authority as experts
in accounting and auditing.

                                      -17-

<PAGE>

We have not authorized  any dealer,  salesperson or any other person to give any
information or to represent anything not contained in this prospectus.  You must
not rely on any unauthorized information. This prospectus does not offer to sell
or buy any shares in any jurisdiction  where it is unlawful.  The information in
this prospectus is current as of June 9, 1999.




                    SUBJECT TO COMPLETION DATED JUNE 14, 1999


                                   PROSPECTUS



                          BENTLEY PHARMACEUTICALS, INC.

                        2,002,489 shares of common stock


                                TABLE OF CONTENTS



RISK FACTORS.............................................................3

USE OF PROCEEDS.........................................................12

SELLING STOCKHOLDERS....................................................13

PLAN OF DISTRIBUTION....................................................15

WHERE YOU CAN FIND MORE INFORMATION ABOUT US............................16

INDEMNIFICATION OF DIRECTORS AND OFFICERS...............................17

LEGAL MATTERS...........................................................17

EXPERTS  ...............................................................17


<PAGE>
                                     PART II

                     INFORMATION NOT REQUIRED IN PROSPECTUS


ITEM 14. OTHER EXPENSES OF ISSUANCE AND DISTRIBUTION.

         The following table sets forth the various  expenses which will be paid
by  the  Company  in  connection  with  the  issuance  and  distribution  of the
securities  being  registered  on  this  registration  statement.   The  selling
stockholders  will not incur any of the expenses  set forth  below.  All amounts
shown are estimates.


SEC Registration Fee                                         $1,827
Legal Fees and Expenses                                       5,000
Accounting Fees and Expenses                                  1,500
Miscellaneous Expenses                                        2,000
                                                         ----------
    Total                                                $   10,327
                                                         ==========


ITEM 15. INDEMNIFICATION OF DIRECTORS AND OFFICERS.

         The Florida  Business  Corporation  Act (the  "Florida  Act") permits a
Florida  Corporation to indemnify a present or former director or officer of the
corporation (and certain other persons serving at the request of the corporation
in related  capacities) for  liabilities,  including legal expenses,  arising by
reason of service in such capacity if such person shall have acted in good faith
and in a manner  he  reasonably  believed  to be in or not  opposed  to the best
interests of the corporation,  and in any criminal proceeding if such person had
no reasonable cause to believe his conduct was unlawful. However, in the case of
actions brought by or in the right of the corporation, no indemnification may be
made with respect to any matter as to which such  director or officer shall have
been adjudged liable, except in certain limited circumstances.

         We maintain a directors and officers  liability  policy with  Lexington
Insurance  Company that  contains an aggregate  limit of liability of $2,000,000
per policy year.

                                      II-1

<PAGE>

ITEM 16. EXHIBITS.


EXHIBIT                                                                     PAGE
  NO.                       DESCRIPTION OF EXHIBIT                           NO.
- --------------------------------------------------------------------------------

4.1      Form of Warrant Agreement between the Registrant and Walter Light dated
         August 27, 1996. (Reference is made to Exhibit 4.6 to the Registrant's
         Registration Statement on Form S-3, Commission File No. 333-28593,
         which exhibit is incorporated herein by reference.)
4.2.1    Consulting  Agreement between the Registrant and Plexus Ventures,  Inc.
         ("Plexus") dated October 23, 1996. (Reference is made to Exhibit 4.7 to
         the Registrant's  Registration  Statement on Form S-3,  Commission File
         No. 333- 28593,  which exhibit is  incorporated  herein by  reference.)
4.2.2(1) Addendum #1 to Consulting  Agreement  between the Registrant and Plexus
         dated July 18, 1997.
4.2.3(1) Amendment to Consulting  Agreement  between the  Registrant  and Plexus
         dated November 24, 1997.
4.3      Warrant Agreement between the Registrant and Ranald Stewart, Jr. dated
         June 9, 1995. (Reference is made to Exhibit 4.8 to the Registrant's
         Registration Statement on Form S-3, Commission File No. 333-28593,
         which exhibit is incorporated herein by reference.)
4.4(1)   Consulting Agreement between the Registrant and Dominick & Dominick,
         Inc. dated December 19, 1997.
4.5(1)   Consulting Agreement between the Registrant and Kinexsys dated October
         30, 1997.
4.6(1)   Warrant Agreement between the Registrant and Baytree Associates, Inc.
         dated June 20, 1999.
4.7      Agreement between the Registrant and Yungtai Hsu ("Hsu") dated February
         1, 1999,  effective  as of December  31,  1998.  (Reference  is made to
         Exhibit  7.1 to the  Registrant's  Form 8-K filed  February  26,  1999,
         Commission  File No. 1-10581,  which exhibit is incorporated  herein by
         reference.)
4.8      Subscription  Agreement  between the Registrant and Hsu, dated February
         11, 1999.  (Reference is made to Exhibit 7.2 to the  Registrant's  Form
         8-K filed February 26, 1999, Commission File No. 1-10581, which exhibit
         is  incorporated   herein  by  reference.)  4.10  Registration   Rights
         Agreement  between the  Registrant  and Hsu,  dated  February 11, 1999.
         (Reference  is made to exhibit 7.3 to the  Registrant's  Form 8-K filed
         February  26,  1999,  Commission  File  No.1-10581,  which  exhibit  is
         incorporated   herein  by  reference.)   4.11  Warrant  issued  by  the
         Registrant for the benefit of Hsu, dated February 11, 1999.  (Reference
         is made to exhibit 7.4 to the Registrant's  Form 8-K filed February 26,
         1999, Commission File No. 1-10581, which exhibit is incorporated herein
         by reference.)
4.9      Registration  Rights  Agreement  between the  Registrant and Hsu, dated
         February  11,  1999.   (Reference   is  made  to  exhibit  7.3  to  the
         Registrant's  Form  8-K  filed  February  26,  1999,   Commission  File
         No.1-10581, which exhibit is incorporated herein by reference.)
4.10     Warrant issued by the Registrant for the benefit of Hsu, dated February
         11, 1999.  (Reference is made to exhibit 7.4 to the  Registrant's  Form
         8-K filed February 26, 1999, Commission File No. 1-10581, which exhibit
         is incorporated herein by reference.)

                                      II-2

<PAGE>

EXHIBIT                                                                     PAGE
  NO.                       DESCRIPTION OF EXHIBIT                           NO.
- --------------------------------------------------------------------------------

4.11     Subscription Agreement between the Registrant and Conrex Pharmaceutical
         Corporation ("Conrex"),  dated February 11, 1999. (Reference is made to
         exhibit  7.5 to the  Registrant's  Form 8-K filed  February  26,  1999,
         Commission  File No. 1-10581,  which exhibit is incorporated  herein by
         reference.)
4.12     Registration Rights Agreement between the Registrant and Conrex,  dated
         February  11,  1999.   (Reference   is  made  to  exhibit  7.6  to  the
         Registrant's  Form 8-K filed  February  26, 1999,  Commission  File No.
         1-10581, which exhibit is incorporated herein by reference.)
5.1(1)   Opinion of Parker Chapin Flattau & Klimpl, LLP.
23.1(1)  Consent of Deloitte & Touche LLP.
23.2(1)  Consent of Parker Chapin Flattau & Klimpl, LLP (included in Exhibit 5.1
         hereto).
24.1(1)  Power of  Attorney  (see  page  II-5 of this  Registration  Statement).

- -----------------------
(1) Filed herewith.



                                      II-3

<PAGE>

ITEM 17. UNDERTAKINGS.

         The undersigned registrant hereby undertakes:

         (1) To file, during any period in which offers or sales are being made,
a post-effective amendment to this registration statement:

                  (i)  To include any prospectus required by Section 10(a)(3) of
the Securities Act;
                  (ii) To reflect in the  prospectus any facts or events arising
after the  effective  date of the  registration  statement  (or the most  recent
post-effective  amendment  thereof)  which,  individually  or in the  aggregate,
represent a fundamental  change in the information set forth in the registration
statement. Notwithstanding the foregoing, any increase or decrease in the volume
of securities offered (if the total dollar value of securities offered would not
exceed that which was  registered) and any deviation from the low or high and of
the estimated  maximum offering range may be reflected in the form of prospectus
filed with the  Commission  pursuant  to Rule 424 (b) if, in the  aggregate  the
changes in volume  and price  represent  no more than 20  percent  change in the
maximum  aggregate  offering price set forth in the "Calculation of Registration
Fee" table in the effective registration statement;
                  (iii) To include any material  information with respect to the
plan of distribution not previously  disclosed in the registration  statement or
any material change to such information in the registration statement.

         (2) That,  for the  purpose  of  determining  any  liability  under the
Securities Act, each such  post-effective  amendment shall be deemed to be a new
registration  statement  relating to the  securities  offered  therein,  and the
offering of such  securities at that time shall be deemed to be the initial bona
fide offering thereof.

         (3) To remove from registration by means of a post-effective  amendment
any of the securities being registered which remain unsold at the termination of
the offering.

         Insofar as indemnification for liabilities arising under the Securities
Act of 1933 (the "Act") may be permitted to directors,  officers and controlling
persons of the registrant  pursuant to the foregoing  provisions,  or otherwise,
the  registrant  has been  advised  that in the  opinion of the  Securities  and
Exchange  Commission such  indemnification is against public policy as expressed
in the Act and is, therefore, unenforceable.

         In the event that a claim for indemnification  against such liabilities
(other than the  payment by the  registrant  of  expenses  incurred or paid by a
director,  officer,  or  controlling  person of the registrant in the successful
defense of any action, suit or proceeding) is asserted by such director, officer
of controlling  person in connection with the securities being  registered,  the
registrant  will,  unless in the  opinion  of its  counsel  the  matter has been
settled by controlling precedent,  submit to a court of appropriate jurisdiction
the question  whether such  indemnification  by it is against  public  policy as
expressed in the Securities  Act and will be governed by the final  adjudication
of such issue.

         The  undersigned  registrant  hereby  undertakes  that, for purposes of
determining  any liability  under the Securities Act of 1933, each filing of the
registrant's  annual  report  pursuant to section  13(a) or section 15(d) of the
Securities  Exchange  Act of 1923  (and,  where  applicable,  each  filing of an
employee  benefit  plan's  annual  report  pursuant  to  section  15(d)  of  the
Securities  Exchange Act of 1923) that is  incorporated  by reference  statement
shall be deemed to be a new  registration  statement  relating to the securities
offered  therein,  and the  offering  of such  securities  at that time shall be
deemed to be the initial bonafide offering thereof.

                                      II-4

<PAGE>
                                   SIGNATURES

         Pursuant  to the  requirements  of the  Securities  Act  of  1933,  the
Registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-3 and has duly caused this Registration
Statement  to be  signed  on its  behalf  by  the  undersigned,  thereunto  duly
authorized,  in the City of North Hampton,  State of New Hampshire,  on the 11th
day of June, 1999.

                                        Bentley Pharmaceuticals, Inc.


                                        By   /s/ James R. Murphy
                                          ______________________________________
                                            James R. Murphy
                                            Chairman of the Board, President and
                                            Chief Executive Officer


                                POWER OF ATTORNEY

         KNOW ALL PERSONS BY THESE  PRESENTS,  that each person whose  signature
appears  below  constitutes  and appoints each of James R. Murphy and Michael D.
Price and each of them with power of substitution,  as his attorney-in-fact,  in
all capacities, to sign any amendments to this registration statement (including
post-effective amendments) and to file the same, with exhibits thereto and other
documents in connection therewith,  with the Securities and Exchange Commission,
hereby  ratifying  and  confirming  all  that  said  attorney-in-facts  or their
substitutes may do or cause to be done by virtue hereof.

         Pursuant  to the  requirements  of the  Securities  Act of  1933,  this
Registration  Statement  has  been  signed  by  the  following  persons  in  the
capacities and on the date indicated.

    Signature                    Title                         Date
    ---------                    -----                         ----


/s/ James R. Murphy         Chairman of the Board, President,  June 11, 1999
- -----------------------     Chief Executive Officer and
James R. Murphy             Director



/s/ Robert M. Stote         Senior Vice-President, Chief       June 11, 1999
- -----------------------     Science Officer and Director
Robert M. Stote


/s/ Michael D. Price        Vice-President, Chief Financial    June 11, 1999
- -----------------------     Officer, Secretary, Treasurer and
Michael D. Price            Director (principal financial and
                            accounting officer

                                      II-5

<PAGE>

    Signature                    Title                         Date
    ---------                    -----                         ----


/s/ Robert J. Gyurik        Vice President of Pharmaceutical   June 11, 1999
- -----------------------     Development and Director
Robert J. Gyurik


 /s/ Charles L. Bolling     Director                           June 11, 1999
- -----------------------
Charles L. Bolling


/s/ Michael McGovern        Director                           June 11, 1999
- -----------------------
Michael McGovern

                                      II-6

<PAGE>

EXHIBIT INDEX

EXHIBIT                                                                     PAGE
  NO.                       DESCRIPTION OF EXHIBIT                           NO.
- --------------------------------------------------------------------------------

4.1      Form of Warrant Agreement between the Registrant and Walter Light dated
         August 27, 1996.  (Reference is made to Exhibit 4.6 to the Registrant's
         Registration  Statement  on Form S-3,  Commission  File No.  333-28593,
         which exhibit is incorporated herein by reference.)
4.2.1    Consulting  Agreement between the Registrant and Plexus Ventures,  Inc.
         ("Plexus") dated October 23, 1996. (Reference is made to Exhibit 4.7 to
         the Registrant's  Registration  Statement on Form S-3,  Commission File
         No. 333- 28593, which exhibit is incorporated herein by reference.)
4.2.2(1) Addendum #1 to Consulting  Agreement  between the Registrant and Plexus
         dated July 18, 1997.
4.2.3(1) Amendment to Consulting  Agreement  between the  Registrant  and Plexus
         dated November 24, 1997.
4.3      Warrant Agreement between the Registrant and Ranald Stewart,  Jr. dated
         June 9, 1995.  (Reference  is made to Exhibit  4.8 to the  Registrant's
         Registration  Statement  on Form S-3,  Commission  File No.  333-28593,
         which exhibit is incorporated herein by reference.)
4.4(1)   Consulting  Agreement  between the  Registrant and Dominick & Dominick,
         Inc. dated December 19, 1997.
4.5(1)   Consulting  Agreement between the Registrant and Kinexsys dated October
         30, 1997.
4.6(1)   Warrant Agreement between the Registrant and Baytree  Associates,  Inc.
         dated June 20, 1997.
4.7      Agreement between the Registrant and Yungtai Hsu ("Hsu") dated February
         1, 1999,  effective  as of December  31,  1998.  (Reference  is made to
         Exhibit  7.1 to the  Registrant's  Form 8-K filed  February  26,  1999,
         Commission  File No. 1-10581,  which exhibit is incorporated  herein by
         reference.)
4.8      Subscription  Agreement  between the Registrant and Hsu, dated February
         11, 1999.  (Reference is made to Exhibit 7.2 to the  Registrant's  Form
         8-K filed February 26, 1999, Commission File No. 1-10581, which exhibit
         is incorporated herein by reference.)
4.9      Registration  Rights  Agreement  between the  Registrant and Hsu, dated
         February  11,  1999.   (Reference   is  made  to  exhibit  7.3  to  the
         Registrant's  Form  8-K  filed  February  26,  1999,   Commission  File
         No.1-10581, which exhibit is incorporated herein by reference.)
4.10     Warrant issued by the Registrant for the benefit of Hsu, dated February
         11, 1999.  (Reference is made to exhibit 7.4 to the  Registrant's  Form
         8-K filed February 26, 1999, Commission File No. 1-10581, which exhibit
         is incorporated herein by reference.)

                                      II-7

<PAGE>
EXHIBIT                                                                     PAGE
  NO.                       DESCRIPTION OF EXHIBIT                           NO.
- --------------------------------------------------------------------------------

4.11     Subscription Agreement between the Registrant and Conrex Pharmaceutical
         Corporation ("Conrex"),  dated February 11, 1999. (Reference is made to
         exhibit  7.5 to the  Registrant's  Form 8-K filed  February  26,  1999,
         Commission  File No. 1-10581,  which exhibit is incorporated  herein by
         reference.)
4.12     Registration Rights Agreement between the Registrant and Conrex,  dated
         February  11,  1999.   (Reference   is  made  to  exhibit  7.6  to  the
         Registrant's  Form 8-K filed  February  26, 1999,  Commission  File No.
         1-10581, which exhibit is incorporated herein by reference.)
5.1(1)   Opinion of Parker Chapin Flattau & Klimpl, LLP.
23.1(1)  Consent of Deloitte & Touche LLP.
23.2(1)  Consent of Parker Chapin Flattau & Klimpl, LLP (included in Exhibit 5.1
         hereto).
24.1(1)  Power of Attorney (see page II-5 of this Registration Statement).

- ------------------------
(1) Filed herewith.

                                      II-8

                                                                   EXHIBIT 4.2.2

                       Addendum #1 to Consulting Agreement
                             Dated October 23, 1996
            Between Plexus Ventures, Inc. and Bentley Pharmaceuticals


         The second  paragraph of the section  "Success  Fees",  page two of the
Agreement is expanded to read as follows:

         Plexus  Ventures will have the option to receive success fees in shares
of Bentley Pharmaceuticals, in cash or in a combination of the two. The value of
Bentley  shares  for  this  purpose  will be  calculated,  on a  transaction  by
transaction basis, as the average of the daily closing prices for the 20 trading
days immediately preceding the signing dates of Letters-of Intent, or equivalent
undertakings, confirming the transactions.

Accepted for:

Plexus Ventures, Inc.                             Bentley Pharmaceuticals

/s/ John F. Chappell                              /s/ James R Murphy
John F. Chappell                                  James R. Murphy
President                                         Chief Executive Officer
Date: July 10, 1997                               Date: 18 July 1997




                                                                   EXHIBIT 4.2.3

PLEXUS VENTURES, INC.

November 24, 1997


Mr. James R. Murphy
Chairman and CEO
Bentley Pharmaceuticals, Inc.
4830 West Kennedy Boulevard
Suite 550
Tampa, FL 33609


Dear Jim:

         We are  pleased to offer  this  letter  Agreement  as  evidence  of the
intention  of the  parties  hereto to both  extend and modify  Plexus  Ventures,
Inc.'s consulting relationship with Bentley Pharmaceuticals,  Inc. as documented
in our letter to you (dated  October 15, 1996)  accepted on October 23, 1996 and
as  amended  via  Addendum  #1  thereto  accepted  July 18,  1997.  This  letter
incorporates  the key provisions of the October 23, 1996 Agreement,  as amended,
and records  certain  changes which are effective  commencing  October 23, 1997.
This letter  Agreement  becomes the  surviving  document  descriptive  of Plexus
Ventures, Inc.'s consulting relationship with Bentley Pharmaceuticals, Inc.

         The Parties to this  Agreement  are Bentley  Pharmaceuticals,  Inc.,  a
corporation  of the State of  Florida,  having  corporate  offices  at 4830 West
Kennedy  Boulevard,  Suite  550,  Tampa,  Florida  33609  (Bentley)  and  Plexus
Ventures,  Inc., a  corporation  of the  Commonwealth  of  Pennsylvania,  having
offices  at 1787  Sentry  Parkway  West,  Building  18,  Suite  301,  Blue Bell,
Pennsylvania 19422 (Plexus).

         The key provisions of the October 23, 1996 Agreement as amended on July
18, 1997 are incorporated below as follows:

         1.       Mission.  Plexus' mission shall be to work with Bentley over a
                  period  of twelve  (12)  months to  identify  appropriate  new
                  acquisition  opportunities for Bentley. Plexus shall work with
                  Bentley to define the  characteristics  of the  properties and
                  companies which can contribute to Bentley sales and profits in
                  the U.S. and targeted European  markets.  Plexus shall further
                  assist  Bentley  in  designing   realistic  deal   structures,
                  including financing strategy for deals, and in negotiating and
                  closing acquisitions.

<PAGE>


Mr. James R. Murphy                      -2-                   November 24, 1997
Bentley Pharmaceuticals, Inc.

         2.       Term.  Bentley and Plexus  envision the term of this Agreement
                  to extend for twelve (12)  months from the date of  acceptance
                  by Bentley;  however,  both  parties  agree to a review of the
                  relationship  after six (6) months time, at which point either
                  Party may terminate the Agreement.

         3.       Compensation.  Bentley  shall  grant  Plexus  thirty  thousand
                  (30,000)  common shares which Plexus shall earn at the rate of
                  two thousand,  five hundred  (2,500) per month during a twelve
                  (12) month commitment by Bentley.

         4.       Success  Fees.  Plexus and Bentley agree that a success fee of
                  the Lehman type [five  percent (5%) on the initial  tranche of
                  value,  four  percent (4%) on the next higher  tranche,  etc.]
                  shall be paid to  Plexus  on each  completed  deal.  Since any
                  contemplated   deal  will  likely   require   non-conventional
                  financing,  it is difficult  to suggest a universal  formula a
                  priori. Plexus and Bentley shall agree on a structure, deal by
                  deal,  as soon as the  Parties  perceive  the  outlines of the
                  transaction.

         5.       Success Fees Payment.  Plexus shall have the option to receive
                  success fees in shares of Bentley, in cash or in a combination
                  of the two. The value of Bentley shares for this purpose shall
                  be calculated,  on a transaction by transaction  basis, as the
                  average  of the  daily  closing  prices  for the  twenty  (20)
                  trading days preceding the signing dates of Letters-of-Intent,
                  or equivalent undertakings, confirming the transactions.

         6.       Expenses.  Plexus  shall bill Bentley  nine  thousand  dollars
                  ($9,000) each six months for recovery of general overheads. In
                  addition,  project  related  out-of-pocket  expenses  shall be
                  separately    recovered   by   Plexus   from   Bentley   under
                  prior-approval guidelines set by Bentley.

                      The following  changes to the above-listed  provisions are
                  effective October 23, 1997:

         1.       Term.  Plexus  and  Bentley  agree to  extend  the term of the
                  Agreement  beyond  October  23, 1997 for the first to occur of
                  (a) six (6) months or (b) the conclusion of the Schwarz Pharma
                  USA and American Home Products  transactions which are subject
                  to  previously  executed   Letters-of-Intent,   or  equivalent
                  undertakings, with those companies.

         2.       Mission. Bentley and Plexus agree that the Mission accepted by
                  Plexus  in  the   October   23,   1996   Agreement   has  been
                  significantly  expanded by mutual  consent of the Parties.  In
                  addition to the Mission  described in that  Agreement,  Plexus
                  shall  continue to provide  Bentley  with help in  identifying
                  potential  financing  sources for Bentley's  transactions with
                  Schwarz Pharma USA and American Home Products and in providing
                  strategic  and business  advice to Bentley in working to close
                  on such financing.
<PAGE>

Mr. James R. Murphy                      -3-                   November 24, 1997
Bentley Pharmaceuticals, Inc.

         3.       Compensation.  During  the  extended  term  of the  Agreement,
                  Bentley  shall grant Plexus four  thousand  (4,000)  shares of
                  Bentley common stock per month.

         4.       Success  Fees.  The  Parties  agree that  success  fees due to
                  Plexus for completed transactions shall be calculated based on
                  the value in cash and stock paid by  Bentley to third  parties
                  to acquire  rights to tangible and  intangible  assets however
                  these are defined.

         5.       Other. All other terms of the October 23, 1996 Agreement shall
                  remain in force during the extension of this Agreement.

         IN WITNESS  WHEREOF,  the parties have executed this Addendum as of the
         23 October, 1997.

Plexus Ventures, Inc.                          Bentley Pharmaceuticals, Inc.


/s/ John F. Chappell                           /s/ James R. Murphy
- -------------------------                      -------------------------
By:   John F. Chappell                         By:   James R. Murphy
      President                                      Chairman and CEO



                                                                     EXHIBIT 4.4


DOMINICK & DOMINICK
- ---------------------
INCORPORATED
Member Principal Exchanges


Financial Square
32 Old Slip
New York, New York 10005
TEL      212 558 8800
FAX      212 797 5268


December 19, 1997

Mr. James R. Murphy
Chairman and Chief Executive Officer
Bentley Pharmaceuticals, Inc.
One Urban Centre, Suite 550
4830 West Kennedy Boulevard
Tampa, FL 33609-2517

Dear Jim:

You have requested that Dominick & Dominick, Incorporated ("Dominick"), act as
the financial advisor for Bentley Pharmaceuticals, Inc. ("Bentley"), on an
on-going basis. We have had certain discussions concerning our role as Bentley's
financial advisor and, in this regard, we are pleased to confirm the following:

1.       Dominick will act as financial advisor for Bentley.

2.       In its capacity as financial advisor, Dominick will be available to
         advise Bentley on investment banking and other matters such as mergers,
         acquisitions, potential public and private financings, bank borrowings,
         licensing and other business arrangements such as corporate
         partnerships.

3.       As part of its on-going financial advisory relationship,  Dominick will
         be available to provide merger and  acquisition  advisory  services for
         Bentley.  In the event  Bentley uses  Dominick's  advisory  services or
         sources (other than with respect to the proposed acquisition of certain
         products and facilities of Schwarz Pharma,  Inc., and Wyeth-Ayerst) and
         (a)  acquires  substantial  stock or assets of another  entity,  or (b)
         another  entity  acquires  substantial  stock  or  assets  of  Bentley,
         Dominick shall be entitled to its normal merger and  acquisition fee on
         such  transaction.  The fee  shall  be 3.0% of the  total  value of the
         transaction.  Said  fee  will be paid on the sale of all or any part of
         Bentley's  Spanishoperation to Schwarz Pharma.  Dominick's fee shall be
         payable  in  cash  at  the  time  of  the   consummation  of  any  such
         transaction.

4.       As part of its financial advisory relationship, Dominick will employ
         its best efforts to introduce Bentley to sources that will consider
         providing financing to Bentley. Specific financing fees will be covered
         in a separate agreement.

5.       Fees described in paragraphs three and four herein shall be payable to
         Dominick for any transactions described therein with any party or
         entity covered thereby with whom
<PAGE>


DOMINICK & DOMINICK                                        Mr. James R. Murphy
- -------------------                                        December 19, 1997
INCORPORATED                                               Page 2
Member Principal Exchanges

         discussions were held during the term of this engagement and with which
         a  transaction  is  consummated  during  the  first  six  month  period
         following the  termination  of this  engagement and shall be 60% of the
         amount if the  transaction is closed in the second six months,  and 30%
         in the third six months following the termination of this engagement.

6.       Dominick will receive reimbursement for all of its reasonable
         out-of-pocket expenses incurred as a result of its activities for and
         on behalf of Bentley, to be reimbursed within 30 days of presentment of
         supporting documentation to Bentley.

7.       Dominick and/or its assigns will purchase for $200.00 a five-year
         warrant to purchase 425,000 common shares (the "Warrant Shares") of
         Bentley immediately upon the Bentley Board of Directors' approval of
         this agreement. The warrant is exercisable at $2.50 per warrant share,
         or $1,062,500, at any time, at the holder's option, in whole or in
         part, during its five year life. The closing price of the common was
         $2.25 on December 18, 1997. The warrant shall be subject to customary
         terms, including antidilution protection as to stock splits and
         recapitalizations, and the holder of the warrant or any shares
         receivable upon exercise will have "piggy-back" registration rights at
         any time Bentley files a registration statement.

8.       Bentley will pay Dominick for its financial advisory services, over and
         above any transaction consummation fees, an initial engagement fee of
         $25,000 upon execution of this agreement. Further, Bentley agrees to
         pay Dominick a quarterly retainer fee of $15,000, payable at the start
         of each quarterly period commencing February 1, 1998. Bentley will pay
         a supplemental $5,000 fee at the start of each quarterly period in
         which Dominick arranges for a European road show, at Bentley's request.

9.       Except for references and descriptions that Bentley may be obligated to
         include in its SEC filings and disclosure statements or as otherwise
         required by law, Bentley shall not issue any press release, statement,
         notice, document or other instrument referring to or mentioning
         Dominick without Dominick's prior written approval.

10.      As Dominick will be acting on Bentley's behalf, Bentley agrees to
         indemnify and hold harmless Dominick (including any affiliated
         companies and respective officers, directors, employees and controlling
         persons) from and against all claims, liabilities, losses, damages and
         expenses (including reasonable expenses of counsel) as they are
         incurred in connection with any proceeding, whether or not Dominick is
         a party thereto, relating to or arising out of such engagement or
         Dominick's role in connection therewith. The foregoing indemnification
         is effective immediately in respect of all events occurring or omitted
         prior to or after the date hereof.

11.      This agreement shall be governed by the laws of the State of New York.


<PAGE>


DOMINICK & DOMINICK                                      Mr. James R. Murphy
- -------------------                                      December 19, 1997
INCORPORATED                                             Page 3
Member Principal Exchanges


12.      This agreement, except for the $25,000 sign-on fee and the terms of
         paragraph 10, is cancelable by Bentley or Dominick by written
         notification up until midnight January 14, 1998. If not cancelled, this
         agreement will be in effect for the 18 months from the above date
         through June 18, 1999.

We look forward to a long and mutually rewarding relationship and we are
confident that we can assist Bentley in various aspects of its business and
intended growth.

                                            Very truly yours,

                                            DOMINICK & DOMINICK INCORPORATED


                                            By: /s/ John R. Doss
                                                --------------------------------
                                                  Mr. John R. Doss
                                                  Executive Vice President


                                            The foregoing is agreed to
                                            and accepted by the Board
                                            of Directors:

                                            BENTLEY PHARMACEUTICALS, INC.


                                            By: /s/ James R. Murphy
                                                --------------------------------
                                                  Mr. James R. Murphy
                                                  Chairman & CEO

                                                                     EXHIBIT 4.5

                       CONSULTING AGREEMENT ("AGREEMENT")
                       --------------------

AGREEMENT entered into as of October 30, 1997, between Kinexsys and Bentley
Pharmaceuticals (hereinafter, the "Company").

1.       Consulting Duties

         Implement an investor interest program that contacts & informs current
         Bentley shareholder's of works underway at the company. Establish a
         comprehensive and reliable database of all investors. Finalize warrant
         conversion. Provide introductions to Kinexsys' network of brokers,
         institutional money managers and high net-worth individuals. Assist
         with the content, format, and timeliness of press releases.

2.0      Compensation and Benefits

2.1      Pursuant to Paragraph 1.1 of this Agreement, Bentley agrees to pay
         Kinexsys a fee of four thousand seven hundred fifty dollars ($4750. US)
         per month for a period of one year, with a review at six months and
         option to extend for a second six months, with the first and sixth
         month payments of nine thousand five hundred dollars ($9500. US) due
         and payable on the date this agreement is executed by Bentley and the
         remainder due in four equal monthly installments of four thousand seven
         hundred and fifty dollars ($4750. US) due and payable on the monthly
         anniversary of the execution of this agreement. If at the end of the
         initial six months Bentley uses its option and renews this contract,
         Kinexsys will receive ($4750.)
         monthly for the remaining six months.

                  Further, Bently agrees to award Kinexsys 100,000 (one hundred
                  thousand) freely transferable incentive warrants written at
                  the signing of this agreement and struck as follows:

                  Thirty thousand (30,000) warrants struck at Bentley's bid
                  price at the opening of trading on the day of the signing of
                  this agreement, and exercisable after the common stock share
                  price trades at or above four dollars ($4. US) per share for
                  twenty trading days. These warrants, if unexercised, will
                  expire nine (9) months from the date of the signing of this
                  agreement.

                  Thirty thousand (30,000) warrants with a strike price of four
                  dollars ($4. US) per share and exercisable after the common
                  stock share price trades at five dollars and fifty cents
                  ($5.50 US) per share for twenty trading days. These warrants,
                  if unexercised, will expire fifteen (15) months from the date
                  of the signing of this agreement.

                  Forty thousand (40,000) warrants with a strike price of four
                  dollars ($4. US) per share, and exercisable at seven dollars
                  and fifty cents ($7.50 US) per share. These warrants if
                  unexercised will expire twenty-four (24) months from the date
                  of the signing of this agreement.

                  a. Bentley Pharmaceuticals agrees to award the one hundred
                  thousand (100,000) warrants previously disclosed in section
                  2.1 at the above agreed upon prices notwithstanding any other
                  section, clause or paragraph hereunder written. In addition,
                  the warrants discussed in section 2.1 will remain the property
                  of Kinexsys notwithstanding any subsequent term of engagement
                  by Bentley Pharmaceuticals or the termination of Kinexsys for
                  any reason or cause whatsoever.

2.2      Bentley shall also reimburse Kinexsys for all reasonable pre-approved
         out-of-pocket expenses which shall be incurred by Kinexsys in
         connection with the performance of all duties and
<PAGE>

         responsibilities    hereunder   including   travel,   lodging,   meals,
         entertainment,  materials  expenses,  telephone and other communication
         costs,  etc.  to be paid  within  seven  days of  receipt by Bentley of
         invoices for such expenses.

2.3      Nothing contained herein shall prevent Bentley from modifying or
         terminating any Company plan, policy, benefit or program.

2.4      Kinexsys hereby agrees to forthwith disclose any conflicts of interest
         which to the best of its knowledge currently exist or which arise
         during the term of this Agreement.

3.0      Termination of Consulting Agreement

3.1      If during the period of this Agreement, Kinexsys shall become unable to
         provide the agreed upon duties and services for a period of more than
         two (2) months, all obligations of Bentley shall terminate.

3.2      Bentley may at any time, by written notice to Kinexsys, terminate the
         consulting services herein described for "Cause" as of the date of such
         notice. For purposes of this Agreement, "Cause" shall be defined as the
         following:

                  the commission by Kinexsys, in connection with the performance
                  of their duties or obligations hereunder, of any act or acts
                  of gross negligence or willful misconduct.

         In the event of such  termination for "Cause"  pursuant to this section
         3.2,  Bentley  shall be liable and shall pay to Kinexsys only that part
         of the  compensation  which has been fully  earned and unpaid as of the
         date of Kinexsys' receipt of such written notice.  Bentley shall not be
         liable for and shall not pay Kinexsys any  compensation  after the date
         of such written notice.  The date of Kinexsys'  receipt of such written
         notice  shall be deemed to be a date not later than three (3)  calendar
         days after its date of mailing or upon its date of receipt by Kinexsys,
         whichever date is sooner.

3.3      Either party may terminate the agreement (i.e., quit) only upon thirty
         (30) days prior written notice to the other party. If Kinexsys gives
         such notice, Bentley, may, in its discretion, waive such notice period
         and the Agreement shall be terminated as of the date of this notice. If
         Bentley gives such notice Kinexsys, may, in its discretion, waive such
         notice period and the Agreement shall be terminated as of the date of
         this notice. Upon termination of this Agreement by Kinexsys pursuant to
         this Section 3.3, thereafter Bentley shall only be obligated to pay any
         previously unpaid and incurred expenses.

4.0      Protection of Confidential Information, Non Competition

4.1      The parties acknowledge that the business of Bentley and its affiliates
         is by its nature a world-wide business and that the products and
         services of Bentley and its affiliates may be used or made anywhere in
         the world. In addition, the business, products, and services of Bentley
         and its affiliates do not require them to maintain a physical location
         close to their customers and participants. In addition, Kinexsys agrees
         to the following restrictive covenants:

4.1.1    Kinexsys will not, during the period of their engagement hereunder or
         at any time thereafter, divulge, use, furnish, disclose or make
         available to anyone other than Bentley or its affiliates, or its
         directors or officers as appropriate, any Confidential Information,
         except as may be necessary in the ordinary course of performing their
         duties as an engaged consultant of Bentley or any affiliate of Bentley.

4.1.2    For purposed of this Agreement, "Confidential Information" shall mean
         any and all information, data and knowledge that (i) has been created,
         discovered, developed, or otherwise become known

                                       -2-

<PAGE>

         to Bentley or any affiliate of Bentley (including,  without limitation,
         information, data, and knowledge created, discovered, developed or made
         known  by  Kinexsys  during  the  period  of or  arising  out of  their
         engagement by Bentley) or in which  property  rights have been assigned
         or otherwise  conveyed to Bentley or any affiliate,  which information,
         data,  or  knowledge  has  commercial  value in the  business  in which
         Bentley  or  any   affiliate   of  Bentley  is  engaged,   except  such
         information,  data, or knowledge,  as is or becomes known to the public
         without violation of the terms of this Agreement, or (ii) arises out of
         or  relates  to the  legal  or  business  affairs  of  Bentley,  or any
         affiliate thereof (including without limitation,  any information which
         Bentley  considers to be privileged.) By way of  illustration,  but not
         limitation, Confidential Information includes trade secrets, processes,
         formulas, know-how, improvements,  discoveries, developements, designs,
         inventions,  techniques, marketing plans, strategies, investment plans,
         forecasts,  new  products,  unpublished  financial  statements or parts
         thereof,  budgets,  projections,   licenses,  prices,  costs,  and  any
         information relating to the legal or business affairs of Bentley or any
         affiliate thereof.

4.1.3    Notwithstanding any provision of this Section 4.1 to the contrary,
         Kinexsys shall be entitled to retain any financial statements, budgets,
         projections, tax statements, organizational documents of Bentley or any
         affiliate thereof which may have been delivered to Kinexsys in their
         capacity as a member or shareholder of Bentley or any affiliate of
         Bentley, and Kinexsys shall have the right to disclose such financial
         statements, budgets, projection, tax statements and organizational
         documents to Kinexsys' accountants, attorneys, and advisors and in
         connection with the provision by any such party of personal financial
         or legal advise or services to Kinexsys.

4.2      If Kinexsys commits a breach of any of the provisions of Section 4.1,
         Bentley shall have the right and remedy to have the provisions of the
         Agreement specifically enforced by way of preliminary and/or permanent
         injunction by any court having jurisdiction, its being acknowledged and
         agreed by Kinexsys and Bentley that any such breach will cause
         irreparable injury to Bentley and that money damages will not provide
         an adequate remedy to Bentley. Such right and remedy shall be in
         addition to, and not in lieu of, any other rights and remedies
         available to Bentley under law or in equity.

4.3      If any of the covenants or provisions contained in Section 4.1 or 4.2,
         or any part thereof, is hereafter construed to be invalid or
         unenforceable in any respect, the same shall not affect the remainder
         of the covenant, covenants or provisions which shall be given the
         maximum effect possible without regard to the invalid portions and the
         remainder shall then be fully enforceable.

4.4      If any of the covenants contained in Section 4.1 or 4.2 or any part
         thereof, is held to be unenforceable because of the duration of such
         provision or the geographical or product/business area covered thereby,
         the parties agree that such provisions shall be reformed and construed
         to reduce the duration and/or area of such provision to the extent
         necessary for enforceability and, in its reduced form, said provision
         shall then be fully enforceable.

4.6      The parties hereto intend to and hereby confer jurisdiction to enforce
         the covenants contained in Sections 4.1 or 4.2 upon the courts of the
         State of California (and the federal courts resident in such State).

5.0      Notices

         All notices or their  communications given pursuant hereto by one party
         to another  shall be in writing and deemed given when (a)  delivered by
         hand, (b) sent by fax/telecopier (with receipt confirmed) provided that
         a copy is mailed the same day by registered or certified mail,  postage
         prepaid,  return  receipt  requested,  or  (c)  when  recieved  by  the
         addressee,  if sent by Express Mail, Federal Express,  or other express
         delivery service (receipt  requested),  in each case to the appropriate
         addresses,  and  fax/telecopier  numbers for Bentley and  Kinexsys  set
         forth below (or to such address and/or fax/telecopier numbers as either
         party may designate by notice to the other from time to time.

                                       -3-

<PAGE>

If to Bentley, to it at:

Bentley Pharmaceuticals
4380 West Kennedy Blvd.
Tampa, FL 33609

Attention:   James R. Murphy


If to Kinexsys, to them at:

Kinexsys
Box 7872
Newport Beach, CA 92660

Attn: Timothy R. Forstrom

Or, delivered by hand.

5.       General

5.1      This Agreement shall be governed by and construed and enforced in
         accordance with the laws of the State of California. Except as
         otherwise expressly provided in this Agreement, if under such law, any
         portion of this Agreement is at any time deemed to be in conflict with
         any applicable statute, rule, regulation, ordinance, or principle of
         law, such portion shall be deemed to be modified or altered to the
         extent necessary to conform thereto, or, if that is not possible, to be
         omitted from this Agreement; and the invalidity of any such portion
         shall not affect the force, effect and validity of the remaining
         portion hereof.

5.2      The article headings contained herein are for reference purposes only
         and shall not in any way affect the meaning or interpretation of this
         Agreement.

5.3      This Agreement sets forth the entire agreement and understanding of the
         parties relating to the subject matter hereof, and supersedes all prior
         agreements, arrangements and understandings, written or oral, relating
         to the subject matter hereof.

5.4      This  Agreement may not be amended,  modified,  superseded,  or waived,
         except by a written instrument executed by both parties,  hereto, or in
         the case of a waiver, by the party waiving  compliance.  The failure of
         either  party  at any  time or  times  to  require  performance  of any
         provision hereof shall in no manner affect the right at a later time to
         enforce the same.  No waiver by either  party of the breach of any term
         or  covenant   contained  in  this  Agreement  whether  by  conduct  or
         otherwise,  in any one or more  instances,  shall be  deemed  to be, or
         construed as, a further or continuing  waiver of any such breach,  or a
         waiver of the breach of any other term or  covenant  contained  in this
         Agreement.

5.5      In the event that any action, suit or other proceeding in law or in
         equity is brought to enforce any provision of this Agreement, and such
         action, suit or proceeding results in a monetary judgment or the
         granting of any injunctive relief, the court costs and reasonable
         attorneys fees of the prevailing party shall, on demand of the
         prevailing party, be paid by the other party.

6.0      Indemnification
                                       -4-

<PAGE>

         Bentley Pharmaceuticals, agrees to indemnify Kinexsys, Timothy R.
         Forstrom and other Indemnified Persons, following the execution of this
         Agreement, as set forth in Attachment A, which is incorporated and made
         part of this Agreement.

7.0      Severability

         If any provision of this Agreement is hereafter construed to be invalid
         or unenforceable in any respect, the same shall not affect the
         remaining provisions of this Agreement, without regard to the invalid
         portion, and any such invalid provisions shall be reformed and
         construed to the extent necessary to permit their enforceability so as
         to reflect the intent of the partes hereto.

8.0      Representation

         Bentley and Kinexsys represent and warrant that each is fully
         authorized and empowered to enter into this Agreement and that the
         performance of each of their respective obligation under this Agreement
         will not violate any agreement between each of them and any other
         person, firm, or organization.

9.0      Survivorship

         The respective rights and obligations of the parties hereunder shall
         survive any termination of Kinexsys' employment or this Agreement to
         the extent necessary to the intended preservation of such rights and
         obligations.

         IN WITNESS WHEREOF, the parties have executed this Agreement as of the
         date first above written.

         Bentley Pharmaceuticals             Kinexsys



         By: /s/ James Murphy                By: /s/ Timothy Forstrom
             ----------------------              -------------------------------
                 James Murphy, CEO                   Timothy Forstrom, Principal


                                       -5-

                                                                     EXHIBIT 4.6

                                                                  June 20, 1997


                          BENTLEY PHARMACEUTICALS, INC.

                     The Transferability of this Warrant is

                       Restricted as Provided in Article 3


         In consideration of $.001 per Warrant and other good and valuable
consideration, the receipt of which is hereby acknowledged by BENTLEY
PHARMACEUTICALS, INC., One Urban Centre, Suite 548, 4830 West Kennedy Boulevard,
Tampa, Florida 33609, a Florida corporation ("the Company"), Baytree Associates,
Inc. is hereby granted the right to purchase, at the initial exercise price of
$3.50 per share, at any time until 5:00 P.M., New York time, on June 20, 2001,
25,000 (twenty-five thousand) shares of the Company's common stock, $.02 par
value per share ("Shares").
         This Warrant initially is exercisable at a price of $3.50 per Share
payable in cash or by certified or official bank check in New York Clearing
House funds, subject to adjustment as provided in Article 6 hereof. Upon
surrender of this Warrant, with the annexed Subscription Form duly executed,
together with payment of the Purchase Price (as hereinafter defined) for the
Shares purchased, at the offices of the Company, the registered holder of this
Warrant ("Holder" or "Holders") shall be entitled to receive a certificate or
certificates for the Shares so purchased.

1.       Exercise of Warrant.

         The purchase rights represented by this Warrant are exercisable at the
option of the Holder hereof, in whole or in part (but not as to fractional
Shares underlying this Warrant), during any period in which this Warrant may be
exercised as set forth above. In the case of the purchase of less than all the

<PAGE>



Shares purchasable under this Warrant, the Company shall cancel this Warrant
upon the surrender hereof and shall execute and deliver a new Warrant of like
tenor for the balance of the Shares purchasable hereunder.

2.       Issuance of Certificates.

         Upon the exercise of this Warrant, the issuance of certificates for
Shares underlying this Warrant shall be made forthwith (and in any event within
five business days thereafter) without charge to the Holder hereof including,
without limitation, any tax which may be payable in respect of the issuance
thereof, and such certificates shall (subject to the provisions of Articles 3
hereof) be issued in the name of, or in such names as may be directed by, the
Holder hereof; provided, however, that the Company shall not be required to pay
any tax which may be payable in respect of any transfer involved in the issuance
and delivery of any such certificates in a name other than that of the Holder
and the Company shall not be required to issue or deliver such certificates
unless or until the person or persons requesting the issuance thereof shall have
paid to the Company the amount of such tax or shall have established to the
satisfaction of the Company that such tax has been paid. The certificates
representing the Shares underlying this Warrant shall be executed on behalf of
the Company by the manual or facsimile signature of one of the present or any
future Chairman or President of the Company and any present or future Vice
President or Secretary of the Company.

3.       Restriction on Transfer of Warrant.

         The Holder of this Warrant, by its acceptance hereof, covenants and
agrees that this Warrant is being acquired as an investment and not with a view
to the distribution hereof, and that it may not be exercised, sold, transferred,
assigned, hypothecated or otherwise disposed of, in whole or in part unless in
the opinion of

                                       -2-

<PAGE>



counsel concurred in by the Company's counsel such transfer is in compliance
with all applicable securities laws.

4.       Price.

         4.1 Initial and Adjusted Purchase Price. The initial purchase price
shall be $3.50 per Share. The adjusted purchase price shall be the price which
shall result from time to time from any and all adjustments of the initial
purchase price in accordance with the provisions of Article 5 hereof.

         4.2 Purchase Price. The term "Purchase Price" herein shall mean the
initial purchase price or the adjusted purchase price, depending upon the
context.

5.       Adjustments of Purchase Price and Number of Shares.

         5.1 Subdivision and Combination. In case the Company shall at any time
subdivide or combine the outstanding Shares, the Purchase Price shall forthwith
be proportionately decreased in the case of subdivision or increased in the case
of combination.

         5.2 Adjustment in Number of Shares. Upon each adjustment of the
Purchase Price pursuant to the provisions of this Article 5, the number of
Shares issuable upon the exercise of this Warrant shall be adjusted to the
nearest full Share by multiplying a number equal to the Purchase Price in effect
immediately prior to such adjustment by the number of Shares issuable upon
exercise of this Warrant immediately prior to such adjustment and dividing the
product so obtained by the adjusted Purchase Price.

                                      -3-
<PAGE>




         5.3 Reclassification, Consolidation, Merger, etc. In case of any
reclassification or change of the outstanding Shares (other than a change in par
value to no par value, or from no par value to par value, or as a result of a
subdivision or combination), or in the case of any consolidation of the Company
with, or merger of the Company into, another corporation (other than a
consolidation or merger in which the Company is the surviving corporation and
which does not result in any reclassification or change of the outstanding
Shares, except a change as a result of a subdivision or combination of such
shares or a change in par value, as aforesaid), or in the case of a sale or
conveyance to another corporation of the property of the Company as an entirety,
the Holder of this Warrant shall thereafter have the right to purchase upon the
exercise of this Warrant the kind and number of shares of stock and other
securities and property receivable upon such reclassification, change,
consolidation, merger, sale or conveyance as if the Holder were the owner of the
Shares underlying this Warrant immediately prior to any such events at the
Purchase Price in effect immediately prior to the record date for such
reclassification, change, consolidation, merger, sale or conveyance as if such
Holder had exercised this Warrant.

6.       (a)      Registration Rights.

                  (i) Each time that the Company proposes for any reason to
Register any of its securities, other than pursuant to a Registration Statement
on Form S-4 or Form S-8 or similar or successor forms (collectively, "Excluded
Forms"), the Company shall promptly give written notice of such proposed
Registration to the registered Holder of this Warrant, which shall offer such
Holder the right to request inclusion of any Registrable Securities in the
proposed Registration.

                                       -4-

<PAGE>



                  (ii) Each Holder shall have 30 days from the receipt of such
notice to deliver to the Company a written request specifying the number of
shares of Registrable Securities such Holder intends to sell and the Holder's
intended plan of disposition.

                  (iii) Upon receipt of a written request pursuant to Section
(6) (a), the Company shall promptly use its best efforts to cause all such
Registrable Securities to be Registered, to the extent required to permit sale
or disposition as set forth in the written request.

                  (iv) Notwithstanding the foregoing, if the managing
underwriter, determines and advises in writing that the inclusion of all
Registrable Securities proposed to be included in the Registration Statement,
together with any other issued and outstanding shares of common stock proposed
to be included therein by holders other than the Holder of Registrable
Securities (such other shares hereinafter collectively referred to as the "Other
Shares"), would interfere with the successful marketing of the securities
proposed to be included in the underwritten public offering, then the number of
such shares to be included in such Registration Statement shall be reduced, and
shares shall be excluded from such underwritten public offering in a number
deemed necessary by such managing underwriter, by excluding equal numbers of the
Registrable Securities and the Other Shares proposed to be registered, pro rata,
based on the number of shares of common stock the Holder proposed to include.
The shares of common stock that are excluded from the Registration Statement
shall be withheld from the market by the holders thereof for a period, not to
exceed 180 days, that the managing underwriter reasonably determines as
necessary in order to effect the underwritten public offering.

                                       -5-

<PAGE>



         (b) Expenses. The Company shall pay all Registration Expenses incurred
by the Company in complying with this Section 6; provided, however, that all
underwriting discounts and selling commissions applicable to the Registrable
Securities covered by registrations effected pursuant to Section 6 (a) hereof
shall be borne by the seller or sellers thereof, in proportion to the number of
Registrable Securities sold by such seller or sellers.


7.       Exchange and Replacement of Warrant.

         This Warrant is exchangeable without expense, upon the surrender hereof
by the registered Holder at the principal executive office of the Company for a
new Warrant of like tenor and date representing in the aggregate the right to
purchase the same number of Shares as are purchasable hereunder in such
denominations as shall be designated by the Holder hereof at the time of such
surrender.
         Upon receipt by the Company of evidence reasonably satisfactory to it
of the loss, theft, destruction or mutilation of this Warrant, and, in case of
loss, theft or destruction, of indemnity or security reasonably satisfactory to
it, and reimbursement to the Company of all reasonable expenses incidental
thereto, and upon surrender and cancellation of this Warrant, if mutilated, the
Company will make and deliver a new Warrant of like tenor, in lieu of this
Warrant.

8.       Elimination of Fractional Interests.

         The Company shall not be required to issue certificates representing
fractions of Shares


                                       -6-

<PAGE>



on the exercise of this Warrant, nor shall it be required to issue scrip or pay
cash in lieu of fractional interests, it being the intent of the parties that
all fractional interests shall be eliminated pursuant to Section 5.2.

9.       Reservation and Listing of Securities.

         The Company shall at all times reserve and keep available out of its
authorized Shares, solely for the purpose of issuance upon the exercise of this
Warrant, such number of Shares as shall be issuable upon the exercise hereof and
thereof. The Company covenants and agrees that, upon exercise of this Warrant
and payment of the Purchase Price therefor, all Shares issuable upon such
exercise shall be duly and validly issued, fully paid and non-assessable. As
long as this Warrant shall be outstanding, the Company shall use its reasonable
best efforts to cause all Shares issuable upon the exercise of this Warrant to
be listed (subject to official notice of issuance) on all securities exchanges
on which the Shares of the Company's common stock may then be listed and/or
quoted on NASDAQ.

10.      Notices.

         All notices, requests, consents and other communications hereunder
shall be in writing and shall be deemed to have been duly given when delivered,
or mailed by registered or certified mail, return receipt requested:

         (a) If to the registered Holder of this Warrant, to the address of such
Holder as shown on the books of the Company; or

                                      -7-
<PAGE>




         (b) If to the Company, to the address set forth on the first page of
this Warrant or to such other address as the Company may designate by notice to
the Holders.

11.      Successors.

         All the covenants, agreements, representations and warranties contained
in this Warrant shall bind the parties hereto and their respective heirs,
executors, administrators, distributees, successors and assigns.

12.      Headings.

         The Article and Section headings in this Warrant are inserted for
purposes of convenience only and shall have no substantive effect.

13.      Law Governing.

         This Warrant shall be construed and enforced in accordance with, and
governed by, the laws of the State of Florida.




                                      -8-
<PAGE>



         WITNESS the seal of the Company and the signature of its duly
authorized officers.

                                           BENTLEY PHARMACEUTICALS, INC.
[SEAL]
                                           By  /s/ James R. Murphy
                                               ---------------------------------
                                                   James R. Murphy
                                                   President & CEO

Attest:



/s/ Michael D. Price
- ---------------------------
Michael D. Price, Secretary


                                      -9-
<PAGE>



                                SUBSCRIPTION FORM

                    (To be Executed by the Registered Holder

                        in order to Exercise the Warrant)

         The undersigned hereby irrevocably elects to exercise the right to
purchase __________ Shares by this Warrant according to the conditions hereof
and herewith makes payment of the Purchase Price of such Shares in full.



                                                --------------------------------
                                                Signature


                                                --------------------------------
                                                Address


Dated:                 , 19    .
       --------------      ----                 --------------------------------

                                                Social Security Number or
                                                Taxpayer's Identification Number


                                      -10-


                                                                     EXHIBIT 5.1



                      PARKER CHAPIN FLATTAU & KLIMPL, LLP
                               COUNSELLORS AT LAW
                          1211 AVENUE OF THE AMERICAS
                            NEW YORK, NY 10036-8735
                                 (212) 704-6000
                               FAX (212) 704-6288


                                                              June 14, 1999



Bentley Pharmaceuticals, Inc.
65 Lafayette Road
No. Hampton, NH 03862


                  Re:      Bentley Pharmaceuticals, Inc.
                           -----------------------------

Dear Sir or Madam:

                  We have acted as counsel to Bentley Pharmaceuticals, Inc. (the
"Company") in connection with its filing of a registration statement on Form S-3
(the "Registration  Statement")  relating to an aggregate of 2,002,489 shares of
common stock, par value $.02 per share (the "Common Stock"),  of the Company, to
be sold by certain selling stockholders,  as set forth on Annex A hereto, and as
more particularly described in the Registration Statement.

                  In our  capacity as counsel to the Company,  we have  examined
the Company's  Amended and Restated  Articles of Incorporation  and By-laws,  as
amended to date, the Company's proposed Certificate of Incorporation and Bylaws,
as set forth in the Proxy  Statement  issued in connection  with the 1999 Annual
Meeting of Stockholders,  and the minutes and other corporate proceedings of the
Company, the Registration Statement and the exhibits thereto.

                  With  respect  to  factual   matters,   we  have  relied  upon
statements and  certificates  of officers of the Company.  We have also reviewed
such other  matters of law and  examined  and relied upon such other  documents,
records  and  certificates  as we  have  deemed  relevant  hereto.  In all  such
examinations  we have  assumed  conformity  with the  original  documents of all
documents  submitted to us as conformed or photostatic  copies, the authenticity
of all  documents  submitted  to us as  originals  and  the  genuineness  of all
signatures on all documents submitted to us.

<PAGE>

Bentley Pharmaceuticals, Inc.
June 14, 1999
Page -2-


                  On the basis of the foregoing, we are of the opinion that:

                  (a) an  aggregate  of  672,489  shares of Common  Stock of the
Company to be sold by the selling  stockholders set forth on Annex A hereto have
been   validly   authorized   and  legally   issued  and  are   fully-paid   and
non-assessable;

                  (b) an  aggregate  of 40,000  shares  of  Common  Stock of the
Company  issuable  upon  exercise  of options  granted to certain  officers  and
directors of the Company and a former officer and director of the Company as set
forth on Annex A, upon issuance and payment in accordance  with the terms of the
respective   option   contracts,   will  be  legally   issued,   fully-paid  and
non-assessable; and

                  (c) an aggregate  of  1,290,000  shares of Common Stock of the
Company  issuable  upon  exercise of certain  warrants to be sold by the selling
stockholders  set  forth  on  Annex A  hereto,  upon  issuance  and  payment  in
accordance with the terms of the respective agreements,  will be legally issued,
fully-paid and non-assessable.

                  The  following  issuances  are subject to the  approval by the
American Stock Exchange of the listing of additional shares of Common Stock: (i)
666,089 of the shares of Common Stock  referred to in paragraph (a); (ii) all of
the shares of Common Stock referred to in paragraph (b); and (iii)  1,140,000 of
the shares of Common Stock referred to in paragraph (c).

                  We hereby  consent to the filing of this opinion as an exhibit
to the Registration  Statement and to the reference made to us under the caption
"Legal  Matters"  in  the  prospectus  constituting  part  of  the  Registration
Statement.

                                         Very truly yours,


                                         /s/ Parker Chapin Flattau & Klimpl, LLP

                                         PARKER CHAPIN FLATTAU & KLIMPL, LLP
<PAGE>
                                                                         ANNEX A
                                                                         -------

                              SELLING STOCKHOLDERS

                                                       Maximum
                                                      Amount to
Selling Stockholder                                    be Sold
- -------------------                                   ---------
Robert M. Stote (a)                                     15,000
Walter Light (c)                                       350,000
Plexus Ventures, Inc. (a)                               66,000
Ranald Stewart, Jr. (b)                                 40,000
Jeffery Harris (a)                                       6,400
Dominick & Dominick (c)                                425,000
Kinexsys (c)                                            40,000
Baytree Associates, Inc. (c)                            25,000
Conrex Pharmaceutical Corporation (a)                  359,282
Yungtai Hsu (a)(c)                                     675,807


- ----------------------
(a)      Refers to paragraph  (a) of the Parker  Chapin  Flattau & Klimpl,  LLP,
         opinion  to Bentley  Pharmaceuticals,  Inc.,  dated June 14,  1999 (the
         "Opinion").

(b)      Refers to paragraph (b) of the Opinion.

(c)      Refers to paragraph (c) of the Opinion.



                                                                    EXHIBIT 23.1


INDEPENDENT AUDITORS' CONSENT

We consent to the incorporation by reference in this  Registration  Statement of
Bentley Pharmaceuticals,  Inc. on Form S-3, of our reports dated March 26, 1999,
appearing in the Annual Report on Form 10-K of Bentley Pharmaceuticals, Inc. for
the year ended  December  31, 1998 and to the  reference to us under the heading
"Experts" in the Prospectus, which is part of this Registration Statement.


/s/ Deloitte & Touche LLP
Tampa, Florida
June 11, 1999



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