BENTLEY PHARMACEUTICALS INC
8-K, 1999-02-26
PHARMACEUTICAL PREPARATIONS
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                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                -----------------

                                    FORM 8-K

                                 CURRENT REPORT
                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934


                                 Date of Report:
                                February 26, 1999



                          BENTLEY PHARMACEUTICALS, INC.
              ----------------------------------------------------
             (Exact name of registrant as specified in its charter)



          Florida                       1-10581              59-1513162 
 ---------------------------           ----------            ---------------    
(State or Other Jurisdiction          (Commission           (I.R.S. Employer
      of Incorporation)               File Number)         Identification No.)



Two Urban Centre, Suite 400, 4890 West Kennedy Blvd., Tampa, FL         33609  
- ----------------------------------------------------------------      ----------
(Address of Principal Executive Offices)                             (Zip Code)


                                 (813) 281- 0961
               --------------------------------------------------
              (Registrant's Telephone Number, Including Area Code)

<PAGE>

Item 2.  Acquisition and Disposition of Assets.
- ------   -------------------------------------


                           On February 11, 1999, Bentley  Pharmaceuticals,  Inc.
                  (the  "Registrant")   acquired  rights  to  certain  U.S.  and
                  international  patents and related  technology  (the "Assets")
                  covering  methods to enhance the absorption of drugs delivered
                  to  biological  tissues,  effective  as of December  31, 1998.
                  Consideration  for the  Assets  was paid to  Yungtai  Hsu,  an
                  individual,  in the form of a cash  payment  of  approximately
                  $1.1  million,  225,800  shares of  common  stock and ten year
                  warrants  to  purchase  450,000  shares  of common  stock.  In
                  addition,  359,282  shares of common  stock were  conveyed  to
                  Conrex Pharmaceutical Corporation,  for total consideration of
                  approximately $2.25 million for the Assets. Furthermore, terms
                  of this transaction  provide for certain royalty payments upon
                  commercialization of products using the technologies.

                           The Registrant  used a portion of the proceeds of the
                  exercise of its publicly held Class A warrants to pay the cash
                  portion  of the  purchase  price.  The  consideration  for the
                  Assets was determined by arms-length  negotiation  between the
                  parties.  There are no material  relationships between Yungtai
                  Hsu or Conrex and the Registrant or any of its affiliates, its
                  directors, its officers or any associate of any such directors
                  or officers.

Item 7.  Financial Information and Exhibits.
- ------   ----------------------------------

(c)      Exhibits:

Exhibit Number            Description

       7.1             Agreement between the Registrant and Yungtai Hsu
                       ("Hsu"), dated February 1, 1999, effective as of December
                       31, 1998.

       7.2             Subscription     Agreement    between    the
                       Registrant and Hsu, dated February 11, 1999.

       7.3             Registration Rights Agreement between the Registrant and
                       Hsu, dated February 11, 1999.

       7.4             Warrant issued by the Registrant for the benefit
                       of Hsu, dated February 11, 1999

                                       -2-

<PAGE>



          7.5         Subscription Agreement between the Registrant and Conrex
                      Pharmaceutical Corporation ("Conrex"), dated February 11,
                      1999.

          7.6         Registration  Rights  Agreement  between the
                      Registrant  and Conrex,  dated  February 11, 1999.

                                       -3-

<PAGE>




                                S I G N A T U R E


                  Pursuant to the requirements of the Securities Exchange Act of
1934,  the  Registrant has duly caused this report to be signed on its behalf by
the undersigned hereunto duly authorized.



                                     BENTLEY PHARMACEUTICALS, INC.
                                     (Registrant)


Date: February 26, 1999              By: /s/ Michael D. Price                   
                                         ---------------------------------------
                                             Michael D. Price
                                        Vice President & Chief Financial Officer



                                       -4-

<PAGE>




                                  EXHIBIT INDEX
                                  -------------


Exhibit Number             Description                             


       7.1                 Agreement  between  the  Registrant  and  Yungtai Hsu
                           ("Hsu")  dated  February  1,  1999,  effective  as of
                           December 31, 1998.

       7.2                 Subscription  Agreement  between the  Registrant  and
                           Hsu, dated February 11, 1999.

       7.3                 Registration  Rights Agreement between the Registrant
                           and Hsu, dated February 11, 1999.

       7.4                 Warrant  issued by the  Registrant for the benefit of
                           Hsu, dated February 11, 1999.

       7.5                 Subscription  Agreement  between the  Registrant  and
                           Conrex Pharmaceutical  Corporation ("Conrex"),  dated
                           February 11, 1999.

       7.6                 Registration  Rights Agreement between the Registrant
                           and Conrex, dated February 11, 1999.


                                       -5-


                            Asset Purchase Agreement

                                     between

                          BENTLEY PHARMACEUTICALS, INC.

                                       and

                                   YUNGTAI HSU



            DATED FEBRUARY 1, 1999 EFFECTIVE AS OF DECEMBER 31, 1998


<PAGE>


                                TABLE OF CONTENTS

                                                                        Page

    ARTICLE I      DEFINITIONS...............................................1  
       1.01        Definitions.  ............................................1  
                                                                                
    ARTICLE II     SALE OF ASSETS AND CLOSING................................5  
       2.01        Purchase And Sale of Assets...............................5  
       2.02        Assumption of Obligations And Liabilities.................5  
       2.03        Retained Liabilities......................................6  
       2.04        Purchase Price; Allocation; Adjustment....................6  
       2.05        Closing...................................................7  
       2.06        Third-Party Consents......................................8  
       2.07        Assignment................................................8  
                                                                                
    ARTICLE III    REPRESENTATIONS AND WARRANTIES OF SELLER..................9  
       3.01        Intentionally Omitted.....................................9  
       3.02        Legal Capacity............................................9  
       3.03        Execution and Binding Effect..............................9  
       3.04        Title.....................................................9  
       3.05        Registrations.............................................9  
       3.06        Intellectual Property....................................10  
       3.07        Absence of Certain Changes or Events.....................10  
       3.08        Contracts................................................11  
       3.09        Negotiations.............................................12  
       3.10        Litigation...............................................12  
       3.11        Compliance with Law......................................12  
       3.12        Licenses and Regulatory Reports..........................13  
       3.13        Inspections and Agreements with Governmental or              
                     Regulatory Authorities.................................13  
       3.14        Affiliate Interests......................................13  
       3.15        Absence of Undisclosed Liabilities.......................14  
       3.16        Customers, Licensees and Suppliers.......................14  
       3.17        Commitments..............................................14  
       3.18        Other Contracts..........................................14  
       3.19        Brokers and Finders......................................14  
       3.20        Tax Matters..............................................15  
       3.21        Disclosure...............................................15  
       3.22        Purchase of Assets.......................................16  
                                                                                
    ARTICLE IV     REPRESENTATIONS AND WARRANTIES OF PURCHASER..............16  
       4.01        Organization and Good Standing...........................16  
       4.02        Authority................................................16  
                                                                                
                                      -ii-
                                                                                
                                                                                
<PAGE>                                                                          
                                                                                
                                                                                
                                                                                
                          TABLE OF CONTENTS (cont'd)                            
                                                                                
                                                                          Page  
                                                                                
       4.03        Execution and Binding Effect.............................17  
       4.04        Brokers and Finders......................................17  
       4.05        Disclosure...............................................17  
                                                                                
    ARTICLE V      COVENANTS OF SELLER......................................17  
       5.01        Regulatory and Other Approvals...........................17  
       5.02        No Solicitations.........................................18  
       5.03        Conduct relating to the Assets...........................18  
       5.04        Licenses; Filings........................................19  
       5.05        Certain Restrictions.....................................19  
       5.06        Delivery of Business Information.........................20  
       5.07        Non-competition..........................................20  
       5.08        Notice and Cure..........................................21  
       5.09        Fulfillment of Conditions................................21  
                                                                                
    ARTICLE VI     COVENANTS OF PURCHASER...................................21  
       6.01        Regulatory and Other Approvals...........................21  
       6.02        Notice and Cure..........................................22  
       6.03        Delivery of Documents....................................22  
       6.04        Fulfillment of Conditions................................22  
                                                                                
    ARTICLE VII    CONDITIONS TO OBLIGATIONS OF SELLER......................22  
       7.01        Representations, Warranties and Covenants................23  
       7.02        Performance..............................................23  
       7.03        Laws.....................................................23  
       7.04        Officer's Certificate....................................23  
       7.05        Regulatory Consents and Approvals........................23  
       7.06        Opinion of Counsel.......................................23  
       7.07        Delivery of Documents....................................23  
       7.08        Proceedings..............................................23  
                                                                                
    ARTICLEV III   CONDITIONS TO OBLIGATIONS OF PURCHASER...................24  
       8.01        Representations, Warranties and Covenants................24  
       8.02        Performance..............................................24  
       8.03        Laws.....................................................24  
       8.04        Regulatory Consents and Approvals........................24  
       8.05        Third Party Consents.....................................24  
       8.06        Delivery of Assets and Documents.........................25  
       8.07        Opinion of Counsel.......................................25  
       8.08        Tax Status...............................................25  
                                                                                
                                      -iii-
<PAGE>                                                                          
                                                                                
                                                                                
                          TABLE OF CONTENTS (cont'd)                            
                                                                                
                                                                          Page  
                                                                                
       8.09        Proceedings..............................................25  
                                                                                
    ARTICLE IX     ADDITIONAL POST-CLOSING COVENANTS........................25  
       9.01        Further Assurances, Post-Closing Cooperation.............25  
       9.02        FDA Approvals............................................27  
       9.03        Adverse Drug Experience; Recalls.........................27  
       9.04        Delivery of Shares.......................................27  
       9.05        Non-Assertion of Patent..................................27  
                                                                                
    ARTICLE X      INDEMNIFICATION..........................................27  
      10.01        Survival of Representations, Warranties, Covenants           
                      and Agreements........................................27  
      10.02        Purchaser's Indemnified Liabilities......................28  
      10.03        Seller's Indemnified Liabilities.........................28  
      10.04        Notice and Defense of a Claim............................28  
                                                                                
    ARTICLE XI     TERMINATION..............................................29  
      11.01        Termination..............................................29  
      11.02        Effect of Termination....................................30  
                                                                                
    ARTICLE XII    MISCELLANEOUS............................................30  
      12.01        Notices..................................................30  
      12.02        Amendments...............................................31  
      12.03        Binding Effect; Assignment...............................31  
      12.04        Announcements............................................32  
      12.05        Expenses.................................................32  
      12.06        Entire Agreement.........................................32  
      12.07        Descriptive Headings.....................................32  
      12.08        Counterparts.............................................32  
      12.09        Governing Law; Jurisdiction..............................32  
      12.10        Arbitration of Disputes..................................32  
      12.11        Severability.............................................33  
      12.12        Confidentiality..........................................34  
                                                                                
                                                                                
                                      -iv-
                                                                                
<PAGE>                                                                          
                   


                                    EXHIBITS

Exhibit A                           Disclosure Schedule
Exhibit B                           Subscription Agreement
Exhibit C                           Registration Rights Agreement
Exhibit D                           Warrant Agreement
Exhibit E                           Assumption Agreement
Exhibit F                           General Assignment and Bill of Sale
Exhibit G                           Form of Assignment of Intellectual Property
Exhibit H                           Form of Opinion of Counsel of Purchaser
Exhibit I                           Form of Opinion of Counsel of Seller
Exhibit J                           Power of Attorney
Exhibit K                           Letter to Drug Master File Staff

                     INDEX TO EXHIBITS - DISCLOSURE SCHEDULE

Schedule 1.01(b)           Contracts
Schedule 1.01(c)           Suppliers and Supply Agreements
Schedule 1.01(g)           Licenses
Schedule 1.01(h)           Patents
Schedule 2.04(a)           Collaborative Parties
Schedule 2.04(c)           Allocation of Purchase Price
Schedule 3.03              Seller's Required Filings
Schedule 3.05              Registrations
Schedule 3.06              License Agreements
Schedule 3.07              Changes or Events
Schedule 3.10              Litigation
Schedule 3.16(a)           Suppliers
Schedule 3.16(b)           Customers and Licensees
Schedule 3.19              Seller's Brokers and Finders
Schedule 4.03              Purchaser's Required Filings

                                       -v-

<PAGE>




                            ASSET PURCHASE AGREEMENT


                  THIS  ASSET  PURCHASE  AGREEMENT  (the  "Agreement")  is dated
February 1, 1999 made and entered into effective as of December 31, 1998 between
YUNGTAI HSU, in his personal  capacity  ("Seller")  and BENTLEY  PHARMACEUTICAL,
INC., a Florida corporation ("Purchaser").

                  WHEREAS,  Seller  purchased the Assets (as defined below) from
Conrex Pharmaceutical Corporation, a New Jersey corporation ("Conrex");

                  WHEREAS, simultaneously herewith the Seller and Purchaser have
entered  into a voting  agreement  relating  to the  purchase of the Assets from
Conrex;

                  WHEREAS, Purchaser desires to purchase from Seller, and Seller
desires  to sell to  Purchaser  the  Assets  (as  defined  below)  which  Seller
purchased from Conrex,  all on the terms and subject to the conditions set forth
herein; and

                  NOW,  THEREFORE,  in  consideration of the premises and of the
mutual agreements herein contained,  and other good and valuable  consideration,
the receipt and sufficiency of which are hereby acknowledged, the parties hereto
agree as follows:


                                    ARTICLE I

                                   DEFINITIONS

         1.01  Definitions.  As used in this  Agreement,  the following  defined
terms have the meanings indicated below:

         "Action or  Proceeding"  means any  action,  claim,  suit,  proceeding,
inquiry,  arbitration or Governmental or Regulatory  Authority  investigation or
audit.

         "Affiliate" means any Person that directly,  or indirectly  through one
of more intermediaries,  controls or is controlled by or is under common control
with the Person specified. For purposes of this definition,  control of a Person
means the power,  direct or  indirect,  to direct or cause the  direction of the
management  and policies of such Person whether by Contract or otherwise and, in
any event and without limitation of the previous sentence, any Person owning ten
percent or more of the voting  securities  of another  Person shall be deemed to
control that Person.

         "Assets" means:

                  (a) the Technology;


<PAGE>




                  (b) the Business Information;

                  (c) the Patents;

                  (d) all Contracts  relating to the Patents and Technology that
are  listed  or  described  on  Schedule  1.01(b)  of the  Disclosure  Schedule,
including without limitation,  Seller's rights to receive goods and services, to
assert  claims and to take other action with  respect to breaches,  defaults and
other violations pursuant to all of the Contracts;

                  (e) all Licenses;

                  (f) lists of suppliers and supply  agreements,  if any, listed
on Schedule 1.01(c) of the Disclosure Schedule; and

                  (g) all batch  records in  existence as of the date hereof and
as of the Closing Date.

         "Assigned  Contracts"  means the  Contracts to be assigned by Seller to
Purchaser as set forth on Schedule 1.01(b) of the Disclosure Schedule.

         "Assigned  Licenses"  means the  Licenses  to be  assigned by Seller to
Purchaser as set forth on Schedule 1.01(g) of the Disclosure Schedule.

         "Associate" means, with respect to any Person, any corporation or other
business  organization  of which such  Person is an officer or partner or is the
beneficial owner, directly or indirectly, of ten percent or more of any class of
equity  securities,  any trust or estate in which such Person has a  substantial
beneficial  interest  or as to which  such  Person  serves as a trustee  or in a
similar  capacity and any relative or spouse of such Person,  or any relative of
such spouse, who has the same home as such Person.

         "Assumed Liabilities" has the meaning ascribed to it in Section 2.02.

         "Business  Day" means a day other than  Saturday,  Sunday or any day on
which banks  located in the State of New York are  authorized  or  obligated  to
close.

         "Business  Information"  means lists of, and all  records,  in written,
electronic, or other formats, and other data, regarding:

                  (a)  pharmaceutical  research  relating  to  the  Patents  and
Technology,

                  (b)  suppliers,  strategies,  formulae,  training  manuals and
customers relating to the development of the Patents and Technology, performance
statistics and all other correspondence,  records,  reports,  computer disks and
programs (including source codes), tapes and other files,

                                       -2-

<PAGE>



information and records,  including,  but not limited to, all regulatory  files,
records  and  other   correspondence,   including   the  DMF  and  all  original
(laboratory)  notebooks in a complete and  unabridged or altered  form,  and the
records, reports and data relating thereto;

                  (c) Seller's files relating to potential  applications  of the
Patents and Technology,

                  (d)  interest  expressed by any Person in  collaborating  with
Seller for researching,  developing,  licensing,  manufacturing or marketing the
Patents and/or the  Technology  for  pharmaceutical  industry  applications  (as
defined by its intended indication);

                  (e) Seller's ownership and operation of the Assets; and

                  (f) the Intellectual Property.

         "Closing" means the closing of the transactions contemplated by Section
2.01.

         "Closing  Date" means  February 11, 1999,  effective as of December 31,
1998, or such other date as Purchaser and Seller mutually agree upon in writing.

         "Contract" means any agreement, understanding, lease, license, evidence
of  indebtedness,  mortgage,  indenture,  security  agreement or other contract,
whether written or oral.

         "Disclosure Schedule" means the record delivered to Purchaser by Seller
and initialed by Seller and Purchaser,  dated as of the date hereof and attached
hereto as Exhibit A,  containing  all  schedules  as are required to be included
pursuant to this Agreement.

         "DMF" means the Drug Master file as compiled by Seller;

         "Governmental  or  Regulatory  Authority"  means any  court,  tribunal,
arbitrator,  authority, agency, commission, official or other instrumentality of
the United States, any foreign country or any domestic or foreign state, county,
city, municipality or other political subdivision.

         "Indemnified Party" has the meaning ascribed to it in Section 10.04.

         "Indemnifying Party" has the meaning ascribed to it in Section 10.04.

         "Intellectual  Property"  means  the  Patents  and all  trade  computer
programs  (including  all source  codes) and  related  documentation,  technical
information,  analytical  methods,  manufacturing,   engineering  and  technical
drawings and know-how relating to the Technology.

         "Laws"  means  all  laws,  statutes,  rules,  regulations,  ordinances,
permits,  orders,  writs,  judgments,  awards,  injunctions  or decrees or other
pronouncements having the effect of law of the

                                       -3-

<PAGE>



United States,  any foreign  country or any domestic or foreign  state,  county,
city  or  other  political  subdivision  or of any  Governmental  or  Regulatory
Authority.

         "Licenses"  means all  licenses,  permits,  certificates  of authority,
authorizations,  approvals, registrations,  franchises, concessions, grants, and
similar consents  granted or issued by any Governmental or Regulatory  Authority
required in connection with researching,  developing,  licensing,  manufacturing
and marketing the  Technology  and Patents,  including  those  Licenses that are
currently being negotiated;  and including without  limitation,  those listed on
Schedule 1.01(g) of the Disclosure Schedule.

         "Liens"  means any mortgage,  pledge,  assessment,  security  interest,
lease, lien,  adverse claim,  levy, charge,  restriction or other encumbrance or
restriction  of any kind, or any  conditional  sale  Contract,  title  retention
Contract or other Contract to give any of the foregoing.

         "Loss" means any and all damages, fines, fees, penalties, deficiencies,
losses and expenses (including, without limitation,  interest, court costs, fees
of attorneys,  accountants  and other experts or other expenses of litigation or
other proceedings or of any claim, default or assessment).

         "Order" means any writ, judgment,  decree,  injunction or similar order
of  any  Governmental  or  Regulatory  Authority,  in  each  such  case  whether
preliminary or final.

         "Patents"  means (i)  United  States  Patent No.  5,023,252  (the "U.S.
Patent") and any reissue thereof,  any reexamination  thereof, and any extension
thereof  and any  patent  application  or  patent  in any  other  country  which
discloses  and claims  subject  matter which is  disclosed  in the U.S.  Patent,
including  the patents  which are listed in Schedule  1.01(h) of the  Disclosure
Schedule,  and (ii) any patent application which is hereafter filed and which is
entitled to the benefit of the filing date of U.S.  Application  No.  08/954,869
(the "869 Application"), filed October 21, 1997, and which claims pharmaceutical
subject matter that is disclosed in the 869 Application and any patent which may
issue  thereon and any  reissue  thereof,  any  reexamination  thereof,  and any
extension thereof.  "Patents" does not mean U.S. patent No. 5,731,303 (hereafter
the "303 Patent") or any patent or patent application which discloses and claims
subject  matter  which  relates  to  a  composition  that  contains  a  cosmetic
skin-treating compound or a cosmetic hair-treating compound, as described in the
303 Patent, or to the use of such cosmetic composition.

         "Person" means any natural person,  corporation,  general  partnership,
limited partnership,  proprietorship, other business organization, trust, union,
association or Governmental or Regulatory Authority.

         "Purchase Price" has the meaning ascribed to it in Section 2.04.

         "Purchaser's Indemnified Liabilities" has the meaning ascribed to it in
Section 10.02.

         "Purchaser" means Bentley Pharmaceuticals, Inc., a Florida corporation.

                                       -4-

<PAGE>



         "Seller"  means  Yungtai Hsu, in his personal  capacity,  or any lawful
successor in interest to Yungtai Hsu.

         "Seller Documents" means the arrangements,  documents,  instruments and
certificates  required to be executed and delivered by Seller in connection with
this Agreement.

         "Seller's  Indemnified  Liabilities"  has the meaning ascribed to it in
Section 10.03.

         "Taxes"  means all Tax Returns of or relating to any foreign,  federal,
state or local tax, assessment, levy, impost, duty, withholding or other similar
governmental charge, all, together with any penalties,  additions to tax, fines,
interest and similar charges thereon or related thereto.

         "Tax Returns" means all returns, including, without limitation, income,
franchise,  sales  and  use,  unemployment   compensation,   excise,  severance,
property,  gross  receipts,  profits,  payroll and  withholding  tax returns and
information returns, and reports.

         "Technology"  means any and all  information  relating to a composition
containing a drug and a compound (hereafter  "Enhancer") which increase the rate
of passage of the drug  across the skin or other  body  membrane,  for  example,
mucous membranes,  or the blood brain barrier and to the  administration of such
composition to treat humans (hereafter  "pharmaceutical  subject matter"),  such
information  including information related to all developmental and commercially
practiced processes and methodologies (including, but not limited to, methods of
using,  storing,   identifying,   measuring,  and  analyzing  the  composition),
formulations,  trade secrets,  know how, formulae and manufacturing,  processing
and  other   technical   information  and  underlying  data  as  it  applies  to
pharmaceutical  industry  application (as defined by the FDA),  prescription and
over-the-counter  application.  "Technology"  does  not mean  information  which
relates  to a cosmetic  composition  which  contains  a  cosmetic  skin-treating
compound or a cosmetic  hair-treating  compound and an Enhancer or to the use of
such cosmetic composition.


                                   ARTICLE II

                           SALE OF ASSETS AND CLOSING

         2.01  Purchase  And Sale of  Assets.  On the terms and  subject  to the
conditions set forth in this Agreement,  at the Closing Purchaser shall purchase
from Seller,  and Seller  shall sell,  transfer,  assign,  convey and deliver to
Purchaser all of Seller's right,  title and interest in and to the Assets,  free
and clear of any and all Liens.  As a result of this  transaction,  Seller shall
retain no interest whatsoever in the Assets.

         2.02  Assumption  of  Obligations  And  Liabilities.  On the  terms and
subject  to the  conditions  set  forth in this  Agreement,  from and  after the
Closing,  Purchaser will assume and pay,  perform,  discharge and be responsible
only for those obligations and liabilities of Seller under the Assigned


                                       -5-

<PAGE>



Contracts  and  Assigned  Licenses  which  accrue  after the  Closing  Date (the
"Assumed  Liabilities");  provided that Purchaser  shall have the right,  in its
sole  discretion,  and without  effect on the Purchase  Price,  to add or delete
Assigned  Contracts or Assigned  Licenses by written notice  delivered to Seller
two Business  Days prior to the Closing  Date,  or such earlier date as Seller's
right to add or delete such Assigned  Contracts or Assigned  Licenses by written
notice delivered to Conrex terminates.

         2.03 Retained  Liabilities.  Notwithstanding  anything herein or in the
Seller  Documents to the contrary,  Purchaser shall not assume or pay,  perform,
discharge or be responsible for any of the obligations or liabilities of Seller,
including but not limited to Seller's liabilities to Virna Pharmaceuticals, Inc.
or with  respect to and arising  out of an  agreement  between  Seller and Virna
Pharmaceuticals, Inc., effective as of December 1, 1990, as further amended (the
"Retained  Liabilities")  other  than  the  Assumed  Liabilities.  Seller  shall
discharge in a timely manner or shall make  adequate  provision for the Retained
Liabilities.  Purchaser  is not a successor  to Seller for any purpose and shall
not be liable for any claim that may exist  against  Seller,  including  but not
limited to any products liability claims.

         2.04     Purchase Price; Allocation; Adjustment.

                  (a)  Purchase  Price.  The  aggregate  purchase  price for the
Assets and for the  covenant of Seller  contained  in Section  5.07 shall be (i)
U.S.  $1,074,000  (the "Cash  Portion of the  Purchase  Price"),  subject to the
adjustments as provided in paragraph (b) below; (ii) an aggregate of $350,000 of
shares of common stock (the  "Shares")  of Purchaser  according to the terms and
conditions of the Subscription  Agreement and the Registration Rights Agreement,
dated as of the  Closing  Date,  substantially  in the forms of Exhibit B and C,
respectively, hereto, (iii) a warrant to purchase 450,000 shares of common stock
of Purchaser  according to the terms and  conditions  of the Warrant  Agreement,
dated as of the  Closing  Date,  substantially  in the form of Exhibit D hereto,
(iv) 5% of the net profits  received by Purchaser or its  successors for fifteen
years from the Closing Date from the commercialization of any products developed
by Purchaser or its successors  from the Assets and (v) the aggregate  amount of
the Assumed Liabilities ((i)-(v) collectively, the "Purchase Price").

                  (b)  Adjustment  of Cash Portion of Purchase  Price.  The Cash
Portion  of the  Purchase  Price  shall be  adjusted  downward  to an  amount of
$1,024,000  (the  "Adjusted  Cash Portion of the  Purchase  Price") to reflect a
payment by  Purchaser  to Seller on December 3, 1998 of a $50,000  due-diligence
deposit.

                  (c) Allocation of Purchase Price.  Purchaser and Seller hereby
agree that for tax purposes the Purchase  Price will be allocated in  accordance
with Schedule  2.04(c) of the Disclosure  Schedule,  which  allocation  shall be
binding upon the  Purchaser  and the Seller,  each of which agrees to report the
effect of the transactions  contemplated hereby on all applicable Tax Returns or
filings in a manner  consistent  with such  schedule.  The Seller hereby assumes
liability for and shall pay all sales,  transfer and similar Taxes incurred as a
result of the sale of the Assets to Purchaser.


                                       -6-

<PAGE>




         2.05     Closing.

                  (a) The Closing will take place at the offices of  Synnestvedt
& Lechner LLP, 2600 Aramak Tower, 1101 Market Street, Philadelphia, Pennsylvania
19107,  or at such other place as Purchaser and Seller  mutually agree, at 10:00
A.M. Eastern Standard Time, on the Closing Date.

                  (b)  Deliveries  by  Purchaser  to  Seller.  At  the  Closing,
Purchaser will:

                           (i)  deliver  to  Seller  an  executed  copy  of this
                  Agreement;

                           (ii) pay the  Adjusted  Cash  Portion of the Purchase
                  Price by wire transfer of immediately  available funds to such
                  account as Seller  may  reasonably  direct by  written  notice
                  delivered to  Purchaser  by Seller at least two Business  Days
                  before the Closing Date;

                           (iii) deliver  to  Seller the Subscription Agreement,
                  Registration  Rights  Agreement  and  Warrant  Agreement, duly
                  executed by Purchaser;

                           (iv) deliver to Seller an assumption agreement, dated
                  as of the Closing Date, substantially in the form of Exhibit E
                  hereto,   duly  executed  by  Purchaser,   pursuant  to  which
                  Purchaser assumes all of the Assumed Liabilities;

                           (v)  deliver to Seller the certificate referred to in
                  Section 7.04; and

                           (vi)  deliver to Seller the  opinion  referred  to in
                 Section 7.06.

                  (c) Deliveries by Seller to Purchaser. Simultaneously with the
deliveries by Purchaser, Seller will:

                           (i)  deliver  to  Seller  an  executed  copy  of this
                  Agreement;

                           (ii) assign and transfer to Purchaser  good and valid
                  title in and to the  Assets  (free and clear of all  Liens) by
                  delivery  of  (A)  a  General  Assignment  and  Bill  of  Sale
                  substantially  in the form of Exhibit F hereto,  duly executed
                  by Seller,  (B) an assignment of the Intellectual  Property in
                  form and  substance  reasonably  satisfactory  to Purchaser to
                  vest in Purchaser  all of Seller's  right,  title and interest
                  in, to and under the  Patents ,  including  but not limited to
                  instruments  of  assignment in a form suitable for filing with
                  the U.S.  Patent  and  Trademark  Office  (including,  but not
                  limited to, United States Patent and Trademark Office Form No.
                  SB/41) to reflect the transfer of the Patents  included in the
                  Assets and, upon filing such  instrument  with the U.S. Patent
                  and  Trademark  Office,  to record the sale of all of Seller's
                  right,  title and interest in, to and under the Patents to the
                  Purchaser, and (C) such other good and


                                       -7-

<PAGE>



                  sufficient instruments of conveyance, assignment and transfer,
                  in form and substance  reasonably  acceptable  to  Purchaser's
                  counsel,  as shall be effective to vest in Purchaser  good and
                  marketable title to the Assets, free of all Liens,  including,
                  but not limited to, written notices from Seller to all parties
                  under any Contract  relating to the Assets,  addressed to such
                  parties,  in  the  form  prepared  by  Seller  and  reasonably
                  acceptable to Purchaser, for the release of such Contracts;

                           (iii) deliver to Purchaser a receipt for the Purchase
                  Price;

                           (iv)  deliver to  Purchaser  regulatory  consents and
                  approvals  and  third-party  consents  referred to in Sections
                  8.04 and 8.05;

                           (v) deliver  to  Purchaser the opinion referred to in
                  Section 8.07;

                           (vi) make available to Purchaser,  at the location of
                  the Assets, all Assets; and

                           (vii) Seller shall deliver to Purchaser, such further
                  instruments of transfer as Purchaser shall reasonably request,
                  to vest in Purchaser all of Sellers' right, title and interest
                  in and to the  Assets,  including,  but not  limited  to,  any
                  documents  evidencing  the  assignment  to  Purchaser  of  the
                  Intellectual  Property (which documents are attached hereto as
                  Exhibit  G), and take such other  actions as  Purchaser  shall
                  reasonably  request to enable Purchaser to use such Assets, as
                  contemplated herein and in the Seller Documents.

         2.06 Third-Party  Consents.  To the extent that any Contract or License
is not assignable without the consent of another party, this Agreement shall not
constitute an assignment or an attempted  assignment  thereof if such assignment
or attempted assignment would constitute a breach thereof.  Seller and Purchaser
shall use their best  efforts to obtain the  consent of such other  party to the
assignment  of any such  Contract or License to  Purchaser in all cases in which
such  consent is or may be required  for such  assignment.  If any such  consent
shall not be obtained,  Seller shall  cooperate with Purchaser in any reasonable
arrangement  designed  to provide  for  Purchaser  the  benefits  intended to be
assigned  to  Purchaser  under  the  relevant  Contract  or  License,  including
enforcement  at the cost and for the  account of Seller of any and all rights of
Seller against the other party thereto arising out of the breach or cancellation
thereof  by such  other  party or  otherwise.  If and to the  extent  that  such
arrangement  cannot be made,  Purchaser  shall have no  obligation  pursuant  to
Section 2.02 or  otherwise  with  respect to any such  Contract or License.  The
provisions  of this Section 2.06 shall not affect the right of Purchaser  not to
consummate the  transactions  contemplated by this Agreement if the condition to
its obligations hereunder contained in Section 8.05 has not been fulfilled.

         2.07  Assignment.  Seller hereby assigns to Purchaser all of his rights
under that certain Asset Purchase  Agreement dated February 1, 1999 effective as
of December 31, 1998 between Conrex and Seller (the "Conrex Agreement").


                                       -8-

<PAGE>



                                   ARTICLE III

                    REPRESENTATIONS AND WARRANTIES OF SELLER

         Seller  understands  that  each of the  following  representations  and
warranties are material and have been relied on by Purchaser. Seller represents,
warrants  and  covenants  to  Purchaser  that the  statements  contained in this
Article III are correct and complete as of the date of this Agreement,  and will
be correct and  complete  as of the Closing  Date (as though made on the Closing
Date),  except as set forth in the Disclosure Schedule delivered to Purchaser on
the date of this Agreement and initialed by Seller and Purchaser.

         3.01     Intentionally Omitted.

         3.02  Legal  Capacity.  Seller  has full  power and legal  capacity  to
execute, deliver and perform this Agreement and the Seller Documents to which he
is a party and to consummate the transactions contemplated hereby and thereby.

         3.03 Execution and Binding Effect. This Agreement has been, and each of
the Seller  Documents  will be, at or prior to the  Closing,  duly  executed and
delivered by Seller and this  Agreement  constitutes,  and the Seller  Documents
when so  executed  and  delivered,  will  constitute  legal,  valid and  binding
obligations  of Seller,  enforceable  against  Seller in  accordance  with their
respective  terms except as such  enforceability  may be limited by  bankruptcy,
insolvency  or similar laws and by equitable  principles.  None of the execution
and  delivery  by Seller of this  Agreement  and the  Seller  Documents,  or the
consummation of the transactions  contemplated  hereby or thereby, or compliance
by Seller with any of the  provisions  hereof or thereof will (a) conflict with,
violate,  result in the breach or termination  of, or constitute a default under
(i) any Laws or (ii) any requirement of any Governmental or Regulatory Authority
applicable  to Seller or by which the Assets may be bound,  or (c) except as set
forth  on  Schedule  3.03  of  the  Disclosure  Schedule,  require  any  filing,
declaration  or  registration  with,  or  permit,  consent,   approval,  waiver,
clearance,  order or  authorization  of, or the  giving of any  notice  to,  any
Governmental  or  Regulatory  Authority  or other  Person  or (d)  result in the
creation of any Lien (other than any lien in favor of Purchaser) upon any of the
Assets.

         3.04 Title.  Seller has good and marketable  title to all of the Assets
and will convey good and marketable title at the Closing,  free and clear of any
and all Liens.  None of the Assets is licensed or otherwise not owned by Seller.
In transferring the Assets to Purchaser,  Seller has no intent to hinder,  delay
or defraud any entity to which Seller owes or will owe any debt, on or after the
Closing Date.

         3.05  Registrations.  The registrations  listed on Schedule 3.05 of the
Disclosure Schedule are the only registrations, as of the Closing Date, required
by any Governmental or Regulatory Authority to develop, manufacture,  market and
sell the Technology  and Patents and any products  resulting from the Technology
and the  Patents.  Such  Registrations  are and will be valid,  current and held
exclusively by Seller as of the Closing Date.

                                       -9-

<PAGE>




         3.06 Intellectual  Property.  The Intellectual Property constitutes all
intellectual  property  which  is  necessary  or used  by  Seller,  to  develop,
manufacture,  market  and  sell  products  developed  from  the  Patents  or the
Technology.  All of the  Intellectual  Property that is owned by Seller is owned
free and clear of all Liens and all  Intellectual  Property  that is licensed or
otherwise  used by Seller is  licensed  pursuant to valid and  existing  license
agreements  and such  interests  are not  subject  to any Liens  other  than the
applicable license agreement,  if any. All such license agreements are set forth
on  Schedule  3.06 of the  Disclosure  Schedule.  Seller has not  granted to any
Person any  License,  interest  or other  right in  respect of the  Intellectual
Property  which does,  or which will,  as of the  Closing or  subsequent  to the
Closing,  permit  any other  Person,  other  than  Purchaser,  to use any of the
Intellectual Property. All Intellectual Property,  including without limitation,
the  Patents,  is valid,  effective  and  enforceable.  Seller is unaware of any
reason that the Intellectual Property, is or could be, invalid or unenforceable,
including,  but not  limited to, the failure of Seller to timely pay any fees or
dues associated with the Intellectual Property. To the best knowledge of Seller,
no Actions or Proceedings are pending or threatened, questioning the validity or
effectiveness  of  any  Intellectual   Property  or  asserting  that  Seller  is
infringing or otherwise adversely affecting the rights of any Person with regard
to any intellectual  property of such Person.  The Intellectual  Property is not
being  infringed  by any Person and  Seller,  to the best of his  knowledge,  is
unaware of any potential  infringement of the  Intellectual  Property.  No third
party  intellectual  property  will be  infringed  as a result of the use of the
Assets.  There are no royalties,  fees or other amounts  payable by or to Seller
with  respect  to any of the  Intellectual  Property.  The  consummation  of the
transactions  contemplated  by this Agreement and the Seller  Documents will not
result in the loss of any Intellectual Property or rights therein.

         3.07     Absence of Certain Changes or Events.

                  (a)  Except as set forth in  Schedule  3.07 of the  Disclosure
Schedule,  Seller has used the Assets only in the  ordinary  and usual course of
his business consistent with past practice, and has not:

                           (i) placed Liens or allowed Liens to be placed on the
                  Assets;

                           (ii) canceled or compromised any material claims,  or
                  waived any other  material  rights,  or sold,  transferred  or
                  otherwise disposed of any of the Assets;

                           (iii)  sold,  transferred,   licensed,   assigned  or
                  otherwise  disposed  of, or permitted to lapse or disclosed to
                  any Person (other than  disclosure to his employees or agents,
                  as  reasonably  necessary  in the ordinary and usual course of
                  his business),  any of the  Intellectual  Property or Business
                  Information;

                           (iv)  suffered  any  material  adverse  change in the
                  manufacturing and development of the Patents or Technology; or


                                      -10-

<PAGE>



                           (v) agreed in writing or otherwise to take any action
                  described in this Section 3.07.

                  (b)  Except as set forth in  Schedule  3.07 of the  Disclosure
Schedule,  Seller is not aware of any event, fact or condition that has occurred
or could  reasonably  be  expected to occur that has or has  resulted  in, or is
reasonably  likely  to  result,  in  a  material  adverse  change  in  research,
development, licensing, manufacture, marketing or sale of the Assets.

         3.08     Contracts.

                  (a) Except as set forth in Schedule  1.01(b) of the Disclosure
Schedule,  none of the Assets is subject to, and except as set forth in Schedule
1.01(b) of the Disclosure Schedule, Seller is not a party to or bound by:

                           (i)  any Contract relating to the Assets;

                           (ii) any  Contract  limiting the freedom of Purchaser
                  or any  affiliate  thereof  following the Closing to engage in
                  any line of business, to own, operate, sell, transfer,  pledge
                  or  otherwise  dispose of or encumber the Assets or to compete
                  with any Person or to engage in any  business  or  activity in
                  any  geographic  area,  within the United States or outside of
                  the United States, relating to the Assets;

                           (iii)  any  Contract  with  any  partnership,   joint
                  venture or other entity;

                           (iv)  any  sale,  loan,  charge,  Contract  or  other
                  transaction  between  Seller  and  any  of  his  shareholders,
                  affiliates, directors or officers; or

                           (v)  any   Contract   that  is  or  might   otherwise
                  reasonably  be  expected  to be  material  to the Assets  (for
                  purposes of this clause (v), a Contract  involving payments to
                  or by Seller  shall be deemed to be material if such  payments
                  are in an aggregate amount of $1,000 or more).

                  (b) Seller is not in breach of any provision of, or in default
(and knows of no event or  circumstance  that with  notice,  or lapse of time or
both,  would  constitute  an event of default)  under the terms of any  Contract
described in Schedule 1.01(b) of the Disclosure Schedule nor is there any Action
or  Proceeding  or grievance  alleging  such a breach or default.  Seller is not
aware, or could not be reasonably aware, of any breach by any other party to any
Contract described in Schedule 1.01(b) of the Disclosure Schedule. All Contracts
described in Schedule  1.01(b) of the Disclosure  Schedule are in full force and
effect,  will  continue  to be in full force and effect  after the  Closing  and
Seller is not  aware,  or could  not be  reasonably  aware,  of any  pending  or
threatened disputes with respect to such Contracts. Seller is not engaged in any
disputes with customers or suppliers,  and to Seller's knowledge (i) no customer
or supplier is considering termination, non-renewal or any adverse


                                      -11-

<PAGE>



modification  of  its  arrangements  with  Seller,  and  (ii)  the  transactions
contemplated  by this  Agreement will not have an adverse affect on the business
relationship with any of its suppliers or customers.

                  (c) All of the  Contracts  (i) have  been  entered  into on an
arm's-length  basis,  (ii) are within the scope of their  corporate  purpose and
ordinary  business,  (iii) do not  violate  applicable  Laws,  (iv) are not of a
loss-making nature, that is known to be likely to result in a loss on completion
or performance and (v) contain  termination  provisions which are reasonable and
customary  for the type of  transactions  and  activities  to which they relate.
Seller has not entered  into any Contract  which cannot be readily  fulfilled or
performed on time without undue or unusual expenditure of money or effort.

         3.09  Negotiations.  Schedule 2.04 (a) of the Disclosure  Schedule sets
forth,  in a  complete  and  exhaustive  manner,  any and all  negotiations  and
discussions  between Seller and any other Person  relating to any of the Assets.
Schedule  2.04(a) of the  Disclosure  Schedule sets forth details  regarding the
status of negotiations for each party listed on such schedule.

         3.10 Litigation. Except as set forth on Schedule 3.10 of the Disclosure
Schedule,  there is not  currently,  and  there  has not been at any  time,  any
Actions  or  Proceedings  pending  or  threatened  by or  against  Seller or any
affiliate  or  employee  of Seller,  or with  respect to the Assets  (including,
without limitation,  products liability claims) or the transactions contemplated
hereby,  at  law  or in  equity  or  before  or by any  Governmental  Entity  or
arbitrator,  which has had or could have a material  adverse affect on Purchaser
or the Assets, and, to the best knowledge of Seller, there is no valid basis for
any such  Action or  Proceeding.  Except as set  forth on  Schedule  3.10 of the
Disclosure Schedule, there is no pending or threatened Action or Proceeding that
seeks to  enjoin  or  obtain  damages  in  respect  of the  consummation  of the
transactions  contemplated  by this  Agreement or that questions the validity of
this Agreement,  any of the Seller Documents or any action to be taken by Seller
in connection with the consummation of the transactions  contemplated  hereby or
thereby.  Seller  is not  subject  to any  Laws  or,  to the  best  of  Seller's
knowledge,  any proposed  Laws,  which has had or could have a material  adverse
affect on the Assets or on Purchaser's  ability to manufacture any products from
the Patents or Technology.

         3.11  Compliance  with  Law.  Seller  has  operated  and  is  currently
conducting  all research,  development,  manufacture,  and sales relating to the
Assets,  and all products  resulting  from the Patents or  Technology  have been
provided, developed, marketed and sold in compliance with all applicable Laws of
Governmental  or Regulatory  Authority.  Seller has not received  notice of, and
does not have knowledge of any such violation or alleged  violation with respect
to the Assets.  Seller has not received  notice of (and does not have  knowledge
of) (a) any  finding  of any  lack of  efficacy  with  respect  to any  products
resulting from the Assets or (b) any findings, determinations, studies, reports,
analyses,  investigations,   inquiries  or  Legal  Proceedings  by  or  for  any
Governmental  or  Regulatory  Authority  with  respect  to the  efficacy  of any
products  resulting from the Assets. As of the date hereof and as of the Closing
Date, all reports relating to the Assets required to be filed by Seller with any
Governmental  or Regulatory  Authority have been or will have been filed and are
and will be accurate and complete in all material respects when filed.

                                      -12-

<PAGE>




         3.12     Licenses and Regulatory Reports.

                  (a) Seller possesses all Licenses  required to be possessed by
it  pursuant  to all  applicable  Laws and all such  Licenses,  as set  forth on
Schedule 1.01(g) of the Disclosure  Schedule,  are in full force and effect. All
Licenses  that Seller has been  negotiating,  or are being  negotiated,  are set
forth on Schedule 1.01(g) of the Disclosure Schedule and include the name of the
contact person of the potential licensee,  the name of the attorney representing
the potential licensee and the status of license being negotiated.  Seller is in
compliance  with all of his  Licenses and there is no  reasonable  basis for the
revocation  or  suspension  of any  thereof.  The  Licenses  constitute  all the
Licenses  required  for  Seller's  ownership  of the  Assets  and the  research,
development, manufacture and marketing of products from the Assets, all of which
are transferable  and will be transferred to Purchaser at the Closing,  and none
of which will expire within the twelve-month  period following the Closing Date.
Seller has furnished to Purchaser copies of all reports of inspections  relating
to the Assets by Governmental or Regulatory Authorities;

                  (b) Seller  has paid all fees,  dues or  assessments,  due and
payable in  connection  with any of the Assets,  including,  but not limited to,
fees  related to the Patents.  There is no  unresolved  violation,  criticism or
exception by any entity with  respect to any report or statement  relating to an
examination of the Assets;

                  (c) Seller has not prepared for filing,  or has not filed with
the FDA or any  foreign  equivalent,  any  filings,  reports,  registrations  or
statements  (including,  but not limited to INDs, NDAs, and ANDAs) pertaining to
the Assets and anything related to Seller's business.

                  (d) Seller has  delivered  to  Purchaser  complete and correct
copies of any and all correspondence between the Company and any Governmental or
Regulatory Authority, including, but not limited to, warning letters, notices of
adverse findings and recall notifications.

         3.13  Inspections  and  Agreements  with   Governmental  or  Regulatory
Authorities.

                  (a) Seller has never received a notice of inspection,  nor has
ever been inspected by any Governmental or Regulatory Authority,  including, but
not limited to, the FDA, OSHA or the Consumer Product Safety Commission.

                  (b)  Seller is not  subject to any  cease-and-desist  or other
order issued by, or a party to any  agreement  or  memorandum  of  understanding
with, any  Governmental  or Regulatory  Authority  relating to or affecting,  or
which may affect the Assets.

         3.14 Affiliate Interests. Neither Seller nor any employee,  debt-holder
or affiliate of Seller:


                                      -13-

<PAGE>



                  (a) owns any  interest  (other than  through the  ownership of
five percent or less of any class of securities  registered under the Securities
Exchange Act of 1934, as amended) in any Person which is a competitor,  supplier
or customer of any business relating to the Assets;

                  (b) owns, in whole or in part,  any  property,  asset or right
used in connection with the research,  development,  manufacture,  marketing and
sales relating to the Assets, or products resulting from the Assets;

                  (c) has  an interest in any Contract pertaining to the Assets;
or

                  (d) owes any money to, or is owed any money by, the Seller.

         3.15 Absence of Undisclosed Liabilities.  The Seller has no liabilities
or  obligations  of  any  nature,  whether  absolute,   accrued,  contingent  or
otherwise,  which  individually  or in the  aggregate are material to the Assets
except for  liabilities  for  performance  obligations  arising in the  ordinary
course of the  business  relating to the Assets (and not as a result of a breach
or default by the Seller) under the Contracts  listed on Schedule 1.01(b) of the
Disclosure Schedule or Contracts not required to be disclosed on that schedule.

         3.16  Customers,  Licensees  and  Suppliers.  Schedule  3.16(a)  of the
Disclosure Schedule sets forth a list of the suppliers (on the basis of revenues
for goods purchased) for any products  relating to the Assets for the year ended
December  31,  1998.  Since  January 1,  1998,  no such  supplier  has ceased or
materially  reduced  its  sales to the  Seller,  or has  threatened  to cease or
materially  reduce such sales and the Seller has not been  engaged in and is not
engaged  in any  dispute  with any of its  suppliers.  Schedule  3.16(b)  of the
Disclosure  Schedule  sets forth all  customers or licensees  that the Seller is
negotiating  with, or has ever negotiated  with, in connection with any products
relating to the Assets.

         3.17  Commitments.  Seller is not  bound  under  any  Contracts  to any
purchase commitments,  blanket purchase orders, minimum research and development
expenditure obligations or other minimum expenditure obligations.

         3.18 Other Contracts.  There are no other Contracts  between the Seller
and any other Person, to acquire any of the Assets,  and no other Person has any
right or option to acquire any of the Assets.

         3.19 Brokers and Finders.  Except as set forth on Schedule  3.19 of the
Disclosure  Schedule,  neither the Seller nor any of his employees or Affiliates
have  employed any broker or finder or incurred any  liability for any brokerage
fees,   commissions  or  finders'  fees  in  connection  with  the  transactions
contemplated by this Agreement or the Seller  Documents.  Except as set forth on
Schedule  3.19 of the  Disclosure  Schedule,  no Person is  entitled to any fee,
commission  or like  payment  in  respect  thereof  based in any  manner  on any
agreement, arrangement or understanding made by or on behalf of the Seller.

                                      -14-

<PAGE>




         3.20     Tax Matters.

                  (a) All Tax  Returns  for any Taxes  that are  required  to be
filed on or before the Closing  Date,  by or on behalf of or with respect to the
Seller or the Assets have been,  or will be,  timely filed with the  appropriate
foreign, federal, state and local authorities.  All Taxes required to be paid by
the Seller on or before the date  hereof have been paid in full on or before the
date  hereof,  and all Taxes  required to be paid by the Seller on or before the
Closing Date will be paid on or before such date. Seller  additionally  warrants
that it shall be solely  responsible  for the  payment of any sales or use taxes
arising from this transaction.

                  (b) All Tax Returns  and the  information  and data  contained
therein have been properly and accurately compiled and completed, fairly present
the information  purported to be shown therein,  and reflect all liabilities for
Taxes for the periods covered by such Tax Returns.  Neither the Internal Revenue
Service nor any other taxing authority is now asserting against the Seller, with
respect to any Tax, any  adjustment,  deficiency or claim for additional  Taxes,
nor are there or have there  been any such  discussions  with or without  notice
from any such taxing authorities with respect thereto nor, to the best knowledge
of the Seller, is there any basis therefor.  There are no outstanding  contracts
or waivers  extending  the  statutory  period of  limitation  applicable  to any
assessment or audit or any Tax or Tax Return of the Seller.

                  (c) No Tax Liens exist on any of the Assets.

                  (d) No written claim has been made by any taxing  authority in
a jurisdiction  where the Seller does not file Tax Returns that the Seller is or
may be subject to taxation by that jurisdiction.

                  (e)  The  Seller  is  not  a  party  to  any  joint   venture,
partnership,  or other arrangement which is treated as a partnership for federal
income tax purposes.

                  (f) There is no Contract or consent made under Section  341(f)
of the Internal  Revenue Code of 1986,  as amended (the  "Code"),  affecting the
Seller.

                  (g) The  Seller  is not a party to any tax  sharing  Contract,
whether formal or informal.

                  (h) Seller  is  not a  "Foreign  Person" within the meaning of
Section 1445(f)(3) of the Code.

         3.21 Disclosure.  Seller has disclosed in writing all information which
is necessary for an accurate  appraisal of the Assets and to research,  develop,
market and manufacture products resulting from the Assets; all information given
by Seller  relating to the Assets was,  when given  accurate,  complete  and not
misleading.  The  representations  and  warranties  of Seller  contained in this
Agreement  do not contain  any untrue  statement  of a material  fact or omit to
state any material fact


                                      -15-

<PAGE>



necessary  in order to make the  statements  and  information  contained in this
Agreement and in the Seller Documents not misleading.  The  representations  and
warranties  of  Seller  contained  in this  Agreement  are  subject  only to the
exceptions   expressly   made   therein   which  apply  only  to  the   specific
representation  or  warranty  with  respect in which they are made;  (b) are not
limited or  conditioned  in any way by the fact that  Purchaser,  its  officers,
employees,  advisors, consultants and auditors have known or could have known by
any means or as a result of the due  diligence  review of Seller  and the Assets
pursued  or to be pursued  by  Purchaser,  its  officers,  employees,  advisors,
consultants and auditors that any of the  representations and warranties made by
Seller  are  not  true,  correct,  exact,  accurate  and  complete;  and (c) the
liability  of Seller with  respect to Purchaser is not limited in any way by the
fact that Purchaser, its officers, employees, advisors, consultants and auditors
have known or could have known by any means or as a result of the due  diligence
review of Seller and the Assets  pursued  or to be  pursued  by  Purchaser,  its
officers,  employees,  advisors,  consultants  and  auditors,  that  any  of the
representations  and  warranties  made by Seller are not true,  correct,  exact,
accurate and complete.

         3.22 Purchase of Assets.  Seller  acquired the Assets from Conrex in an
arms-length  transaction.  Conrex  has no  rights  to  reacquire  the  Assets or
challenge or affect in any way detrimental to Purchaser the validity of its sale
of the  Assets to Seller or  Seller's  sale of the Assets to  Purchaser.  On the
Closing  Date,  the  Purchaser  shall have all of the rights of Seller under the
Conrex Agreement.


                                   ARTICLE IV

                   REPRESENTATIONS AND WARRANTIES OF PURCHASER

         Purchaser  understands that each of the following  representations  and
warranties are material and have been relied on by Seller. Purchaser represents,
warrants and covenants to Seller that the  statements  contained in this Article
IV are correct and complete as of the date of this Agreement and will be correct
and complete as of the Closing Date (as though made on the Closing Date).

         4.01  Organization  and Good Standing.  Purchaser is a corporation duly
organized,  validly existing and in good standing under the laws of the State of
Florida,  and has all requisite  power and authority to carry on its business as
it is as of the date hereof being conducted, and to execute, deliver and perform
this Agreement.

         4.02 Authority.  The execution and delivery to Seller of this Agreement
by Purchaser,  the performance by Purchaser of its obligations hereunder and the
consummation by Purchaser of the transactions contemplated hereby have been duly
authorized by the board of directors of Purchaser, and no other corporate act or
proceeding  on the part of Purchaser is necessary to approve the  execution  and
delivery  of  this  Agreement,   the  performance  of  Purchaser's   obligations
hereunder, or the consummation of the transactions contemplated hereby.


                                      -16-

<PAGE>



         4.03  Execution  and  Binding  Effect.  This  Agreement  has been  duly
executed and delivered by Purchaser and this Agreement  constitutes legal, valid
and  binding   obligations  of  Purchaser,   enforceable  against  Purchaser  in
accordance  with its  terms  except as such  enforceability  may be  limited  by
bankruptcy,  insolvency or similar laws and by equitable principles. Neither the
execution and delivery by Purchaser of this Agreement,  nor the  consummation of
the transactions  contemplated  hereby, nor the compliance by Purchaser with any
of the provisions hereof will (a) conflict with, or result in the breach of, any
provision of Purchaser's  Certificate  of  Incorporation  and Bylaws,  as of the
Closing Date,  (b) conflict with,  violate,  result in the breach or termination
of, or  constitute a default  under (i) any  Contract,  to which  Purchaser is a
party or by which  Purchaser  is bound or  subject,  (ii) any Laws or (iii)  any
requirement of any Governmental or Regulatory Authority applicable to Purchaser,
or (c) except as set forth on Schedule 4.03 of the Disclosure Schedule,  require
any filing,  declaration or  registration  with, or permit,  consent,  approval,
waiver,  clearance,  order or authorization  of, or the giving of any notice to,
any Governmental or Regulatory Authority or other Person.

         4.04  Brokers and  Finders.  Purchaser  has not  employed any broker or
finder or incurred any liability for any brokerage fees, commissions or finders'
fees in connection with the  transactions  contemplated by this Agreement or the
Seller Documents.  No Person is entitled to any fee,  commission or like payment
in  respect  thereof  based  in any  manner  on any  agreement,  arrangement  or
understanding made by or on behalf of Purchaser

         4.05  Disclosure.  The  representations  and  warranties  of  Purchaser
contained in this  Agreement  do not contain any untrue  statement of a material
fact  or omit to  state  any  material  fact  necessary  in  order  to make  the
statements  and  information  contained  in  this  Agreement  and in the  Seller
Documents not misleading.


                                    ARTICLE V

                               COVENANTS OF SELLER

         Seller  covenants and agrees with Purchaser that, at all times from and
after the date hereof  until the Closing  and,  with  respect to any covenant or
agreement  by its terms to be  performed  in whole or in part after the Closing,
for  the  period  specified  herein  or,  if  no  period  is  specified  herein,
indefinitely,  Seller will  comply with all  covenants  and  provisions  of this
Article V, except to the extent Purchaser may otherwise consent in writing.

         5.01  Regulatory  and  Other  Approvals.   Seller  will  (a)  take  all
commercially reasonable steps necessary or desirable, and proceed diligently and
in good  faith and use all  commercially  reasonable  efforts,  as  promptly  as
practicable to obtain all consents, approvals or actions of, to make all filings
with and to give all notices to  Governmental  or Regulatory  Authorities or any
other Person  required of Seller to  consummate  the  transactions  contemplated
hereby and by the Seller  Documents,  (b)  provide  such other  information  and
communications to such Governmental or Regulatory Authorities


                                      -17-

<PAGE>



or other Persons as Purchaser or such Governmental or Regulatory  Authorities or
other Persons may reasonably  request in connection  therewith and (c) cooperate
with Purchaser as promptly as  practicable in obtaining all consents,  approvals
or actions of, making all filings with and giving all notices to Governmental or
Regulatory  Authorities or other Persons required of Purchaser to consummate the
transactions  contemplated  hereby  and by the  Seller  Documents.  Seller  will
provide  prompt  notification  to  Purchaser  when any such  consent,  approval,
action,  filing or notice  referred to in clause (a) above is  obtained,  taken,
made or given, as applicable,  and will advise  Purchaser of any  communications
(and,  unless precluded by Law, provide copies of any such  communications  that
are in writing) with any  Governmental  or Regulatory  Authority or other Person
regarding any of the  transactions  contemplated by this Agreement or any of the
Seller Documents.

         5.02 No  Solicitations.  Seller  will not take,  nor will it permit any
Affiliate of Seller (or  authorize or permit any  investment  banker,  financial
advisor,  attorney,  accountant or other Person  retained by or acting for or on
behalf of Seller or any such  Affiliate) to take,  directly or  indirectly,  any
action to initiate, assist, solicit, receive, negotiate, encourage or accept any
offer or inquiry  from any Person (a) to reach any  agreement  or  understanding
(whether  or  not  such  agreement  or  understanding  is  absolute,  revocable,
contingent or conditional) for, or otherwise attempt to consummate,  the sale of
the  Assets to any Person  other  than  Purchaser  or its  Affiliates  or (b) to
furnish or cause to be furnished any  information  with respect to the Assets to
any Person who Seller or such  Affiliate  (or any such  Person  acting for or on
their  behalf)  knows or has reason to believe is in the process of  considering
any  acquisition  of the Assets.  If Seller or any such  Affiliate  (or any such
Person  acting  for or on their  behalf)  receives  from any  Person  any offer,
inquiry or informational  request referred to above, Seller will promptly advise
such  Person,  by written  notice,  of the terms of this  Section  5.02 and will
promptly,  orally and in writing,  advise  Purchaser  of such offer,  inquiry or
request and deliver a copy of such notice to Purchaser.

         5.03  Conduct  relating to the Assets.  Seller will operate and conduct
his business  relating to the Assets only in the ordinary course consistent with
past practice such that, at the Closing, no representation,  warranty, covenant,
obligation or agreement will be breached and no condition in this Agreement will
remain  unfulfilled  by reason of the actions or  omissions  of Seller.  Without
limiting the generality of the foregoing, Seller will:

                  (a) use commercially reasonable efforts to (i) preserve intact
the present business organization and reputation of the business relating to the
Assets, (ii) maintain the Assets in good order and condition, and (iii) maintain
the goodwill of customers,  suppliers,  lenders and other Persons to whom Seller
sells goods or provides  services or with whom Seller  otherwise has significant
business relationships in connection with the Assets;

                  (b) except to the extent required by applicable Law, cause all
the Business  Information  to be maintained  in the usual,  regular and ordinary
manner;

                                      -18-

<PAGE>



                  (c) not sell, assign, license, transfer or permit to lapse any
right or obligation with respect to the Intellectual Property, including but not
limited  to  making  all  filings  required  to be made with  respect  to and to
preserve all rights to the Intellectual Property; and

                  (d) comply, in all material respects, with all Laws applicable
to the Assets and promptly following receipt thereof to give Purchaser copies of
any notice  received  from any  Governmental  or  Regulatory  Authority or other
Person alleging any violation of any such Laws.

         5.04 Licenses; Filings. As promptly as practicable, Seller will deliver
copies  of all  License  applications  and  other  filings  made  by  Seller  in
connection with the operation of the Assets after the date hereof and before the
Closing Date with any Governmental or Regulatory Authority.

         5.05     Certain Restrictions.  Seller will refrain from:

                  (a) acquiring or disposing of any of the Assets;

                  (b) entering into, amending, modifying, terminating (partially
or completely),  granting any waiver under or giving any consent with respect to
any Contract or any License relating to the Assets;

                  (c) violating,  breaching or defaulting  under in any material
respect, or taking or failing to take any action that (with or without notice or
lapse of time or both) would  constitute  a material  violation or breach of, or
default under,  any term or provision of any Contract or License relating to the
Assets;

                  (d) incurring,  purchasing,  canceling, prepaying or otherwise
providing for a complete or partial  discharge in advance of a scheduled payment
date with respect to, or waiving any right of Seller under,  any liability of or
owing to Seller in connection with any of the Assets, other than in the ordinary
course of business consistent with past practice;

                  (e) entering into  a mortgage, pledge or otherwise  subjecting
to Lien any of the Assets;

                  (f) engaging with any Person in any merger,  consolidation  or
combination to which such Person is a party, any sale, dividend,  split or other
disposition  of capital  stock or other  equity  interests of such Person or any
sale,  dividend or other  disposition of all or substantially  all of the assets
and properties of such Person.

                  (g)  engaging in any  transaction  with  respect to the Assets
with any employee,  debt-holder,  officer,  director,  Affiliate or Associate of
Seller, or any Associate of any such employee, debt-holder, officer, director or
Affiliate,  either outside the ordinary course of business  consistent with past
practice or other than on an arm's-length basis;

                                      -19-

<PAGE>



                  (h) entering into a contract which is deemed to be an Assigned
Contract; and

                  (i) entering  into  any Contract to do or engage in any of the
foregoing.

         5.06 Delivery of Business Information. On the Closing Date, Seller will
deliver or make  available  to Purchaser at the location at which the Assets are
held all of the Business  Information relating to the Assets which are or should
be in Seller's possession, and if at any time after the Closing Seller discovers
in his possession or under his control any other  Business  Information or other
Assets, it will forthwith  deliver such Business  Information or other Assets to
Purchaser.

         5.07     Non-competition.

                  (a) Seller  will,  for a period of ten years from the  Closing
Date,  refrain from,  either alone or in conjunction  with any other Person,  or
directly or indirectly through his present or future Affiliates:

                           (i)  causing  or  attempting  to  cause  any  client,
                  customer or supplier of Purchaser  to terminate or  materially
                  reduce its business  with  Purchaser or any of its  Affiliates
                  relating to the Assets; or

                           (ii) participating or engaging in (other than through
                  the  ownership  of  five  percent  or  less  of any  class  of
                  securities  registered  under the  Securities  Exchange Act of
                  1934, as amended),  or otherwise lending assistance (financial
                  or otherwise) to any Person  participating  or engaged in, any
                  business relating to the Assets.

                  (b) The  parties  hereto  recognize  that the Laws and  public
policies  of the  various  states  of the  United  States  may  differ as to the
validity  and  enforceability  of  covenants  similar to those set forth in this
Section.  It is the intention of the parties that the provisions of this Section
be enforced to the fullest  extent  permissible  under the Laws and  policies of
each   jurisdiction  in  which   enforcement   may  be  sought,   and  that  the
unenforceability  (or the  modification  to conform to such Laws or policies) of
any provisions of this Section shall not render  unenforceable,  or impair,  the
remainder of the  provisions of this Section.  Accordingly,  if any provision of
this Section shall be determined to be invalid or unenforceable, such invalidity
or unenforceability  shall be deemed to apply only with respect to the operation
of such provision in the particular  jurisdiction in which such determination is
made and not with respect to any other provision or jurisdiction.

                  (c) The parties hereto  acknowledge  and agree that any remedy
at Law for any breach of the provisions of this Section would be inadequate, and
Seller  hereby  consents to the granting by any court of an  injunction or other
equitable relief, without the necessity of actual monetary loss being proved, in
order that the breach or threatened breach of such provisions may be effectively
restrained.


                                      -20-

<PAGE>



         5.08 Notice and Cure.  Seller will notify  Purchaser in writing  (where
appropriate,   through   updates   to   the   Disclosure   Schedule)   of,   and
contemporaneously  will provide  Purchaser with true and complete  copies of any
and all  information  or documents  relating  to, and will use all  commercially
reasonable  efforts  to cure  before the  Closing,  any  event,  transaction  or
circumstance,  as soon as  practicable  after it becomes  known,  or  reasonably
should have become known, to Seller, occurring after the date of this Agreement,
that  causes or will  cause any  covenant  or  agreement  of Seller  under  this
Agreement   to  be  breached  or  that   renders  or  will  render   untrue  any
representation  or warranty of Seller contained in this Agreement as if the same
were  made on or as of the  date of such  event,  transaction  or  circumstance.
Seller also will notify Purchaser in writing (where appropriate, through updates
to the Disclosure Schedule) of, and will use all commercially reasonable efforts
to cure,  before the Closing,  any violation or breach,  as soon as  practicable
after it becomes known, or reasonably  should have become known,  to Seller,  of
any  representation,  warranty,  covenant  or  agreement  made by Seller in this
Agreement,  whether  occurring or arising  before,  on or after the date of this
Agreement. No notice given pursuant to this Section shall have any effect on the
representations, warranties, covenants or agreements contained in this Agreement
for purposes of determining  satisfaction of any condition  contained  herein or
shall in any way limit Purchaser's right to seek indemnity under Article X.

         5.09 Fulfillment of Conditions.  Seller will execute and deliver at the
Closing each of the Seller  Documents that Seller is required  hereby to execute
and deliver as a condition to the Closing, will take all commercially reasonable
steps necessary or desirable and proceed diligently and in good faith to satisfy
each other condition to the obligations of Purchaser contained in this Agreement
and will not take or fail to take any action that could  reasonably  be expected
to result in the nonfulfillment of any such condition.


                                   ARTICLE VI

                             COVENANTS OF PURCHASER

         Purchaser  covenants and agrees with Seller that, at all times from and
after the date hereof  until the Closing,  and,  with respect to any covenant or
agreement  by its terms to be  performed  in whole or in part after the Closing,
for  the  period  specified  herein  or,  if  no  period  is  specified  herein,
indefinitely,  Purchaser  will comply with all covenants and  provisions of this
Article VI, except to the extent Seller may otherwise consent in writing.

         6.01   Regulatory  and  Other   Approvals.   Purchaser  will  (a)  take
commercially reasonable steps necessary or desirable, and proceed diligently and
in  good  faith  and  use  commercially   reasonable  efforts,  as  promptly  as
practicable to obtain all consents, approvals or actions of, to make all filings
with and to give all notices to  Governmental  or Regulatory  Authorities or any
other Person required of Purchaser to consummate the  transactions  contemplated
hereby and by the Seller  Documents,  (b)  provide  such other  information  and
communications to such  Governmental or Regulatory  Authorities or other Persons
as Seller or such Governmental or Regulatory Authorities or other Persons may

                                      -21-

<PAGE>



reasonably  request in connection  therewith  and (c)  cooperate  with Seller as
promptly as  practicable  in obtaining  all  consents,  approvals or actions of,
making all filings  with and giving all notices to  Governmental  or  Regulatory
Authorities or other Persons  required of Seller to consummate the  transactions
contemplated  hereby and by the Seller Documents.  Purchaser will provide prompt
notification to Seller when any such consent, approval, action, filing or notice
referred  to in  clause  (a)  above  is  obtained,  taken,  made  or  given,  as
applicable,  and will advise Seller of any communications (and, unless precluded
by Law, provide copies of any such  communications that are in writing) with any
Governmental  or  Regulatory  Authority  or other  Person  regarding  any of the
transactions contemplated by this Agreement or any of the Seller Documents.

         6.02 Notice and Cure.  Purchaser  will notify Seller in writing of, and
contemporaneously  will provide Seller with true and complete  copies of any and
all  information  or  documents  relating  to,  and  will  use all  commercially
reasonable  efforts  to cure  before the  Closing,  any  event,  transaction  or
circumstance,  as soon as  practicable  after it becomes  known,  or  reasonably
should  have  become  known,  to  Purchaser,  occurring  after  the date of this
Agreement,  that causes or will cause any  covenant or  agreement  of  Purchaser
under this  Agreement to be breached or that  renders or will render  untrue any
representation  or warranty of Purchaser  contained in this  Agreement as if the
same were made on or as of the date of such event,  transaction or circumstance.
Purchaser  also will notify Seller in writing of, and will use all  commercially
reasonable efforts to cure, before the Closing, any violation or breach, as soon
as practicable  after it becomes known, or reasonably  should have become known,
to Purchaser,  of any  representation,  warranty,  covenant or agreement made by
Purchaser in this Agreement,  whether  occurring or arising before,  on or after
the date of this Agreement.  No notice given pursuant to this Section shall have
any effect on the representations, warranties, covenants or agreements contained
in this  Agreement  for purposes of  determining  satisfaction  of any condition
contained  herein or shall in any way  limit  Seller's  right to seek  indemnity
under Article X.

         6.03  Delivery  of  Documents.  Purchaser  will  execute and deliver to
Seller the Subscription  Agreement,  the  Registration  Rights Agreement and the
Warrant.

         6.04  Fulfillment of Conditions.  Purchaser will take all  commercially
reasonable  actions  necessary or desirable and proceed  diligently  and in good
faith to satisfy each other condition to the obligations of Seller  contained in
this  Agreement  and  will  not  take  or fail to take  any  action  that  could
reasonably be expected to result in the nonfulfillment of any such condition.


                                   ARTICLE VII

                       CONDITIONS TO OBLIGATIONS OF SELLER

         The obligations of Seller hereunder are subject to the fulfillment,  at
or before the Closing, of each of the following  conditions (all or any of which
may be waived in whole or in part by Seller in his sole discretion):

                                      -22-

<PAGE>



         7.01   Representations,   Warranties   and   Covenants.   Each  of  the
representations and warranties made by Purchaser in this Agreement shall be true
and correct in all material  respects on the date hereof and on the Closing Date
as though  such  representation  or  warranty  was made on and as of the Closing
Date.

         7.02 Performance. Purchaser shall have performed and complied with each
agreement, covenant and obligation required by this Agreement to be so performed
or complied with by Purchaser at or before the Closing.

         7.03 Laws.  There  shall not be in effect on the  Closing  Date any Law
that became effective after the date of this Agreement restraining, enjoining or
otherwise  prohibiting  or  making  illegal  the  consummation  of  any  of  the
transactions contemplated by this Agreement or any of the Seller Documents.

         7.04 Officer's Certificate.  Purchaser shall have delivered to Seller a
certificate,  dated the Closing  Date and  executed by an officer of  Purchaser,
certifying  resolutions  of  Purchaser's  Board  of  Directors  authorizing  the
execution,  delivery and performance of this Agreement, together with incumbency
and a signature certificate regarding the officer signing on Purchaser's behalf.

         7.05  Regulatory  Consents and Approvals.  All consents,  approvals and
actions of, filings with and notices to any Governmental or Regulatory Authority
necessary to permit Seller and Purchaser to perform their obligations under this
Agreement  and the  Operative  Agreements  and to  consummate  the  transactions
contemplated  hereby  and  thereby  (a) shall have been duly  obtained,  made or
given, (b) shall be in form and substance reasonably  satisfactory to Seller (c)
shall not be  subject to the  satisfaction  of any  condition  that has not been
satisfied  or  waived  and  (d)  shall  be in full  force  and  effect,  and all
terminations or expirations of waiting  periods  imposed by any  Governmental or
Regulatory   Authority  necessary  for  the  consummation  of  the  transactions
contemplated by this Agreement and the Seller Documents, shall have occurred.

         7.06  Opinion of Counsel.  Seller  shall have  received  the opinion of
Parker Chapin  Flattau & Klimpl,  LLP,  counsel to Purchaser,  dated the Closing
Date, substantially in the form and to the effect of Exhibit H hereto.

         7.07 Delivery of Documents. At the Closing, Purchaser shall execute and
deliver to Seller the documents described in Section 2.05(b).

         7.08 Proceedings.  All proceedings to be taken on the part of Purchaser
in  connection  with the  transactions  contemplated  by this  Agreement and all
documents  incident  thereto  shall  be  reasonably  satisfactory  in  form  and
substance to Seller, and Seller shall have received copies of all such documents
and other  evidences as Seller may reasonably  request in order to establish the
consummation  of  such  transactions  and  the  taking  of  all  proceedings  in
connection therewith.

                                      -23-

<PAGE>



                                  ARTICLE VIII

                     CONDITIONS TO OBLIGATIONS OF PURCHASER

         The obligations of Purchaser  hereunder are subject to the fulfillment,
at or before the Closing,  of each of the  following  conditions  (all or any of
which may be waived in whole or in part by Purchaser in its sole discretion):

         8.01   Representations,   Warranties   and   Covenants.   Each  of  the
representations  and  warranties  made by Seller in this  Agreement  (other than
those made as of a specified  date earlier than the Closing  Date) shall be true
and correct in all  material  respects  on and as of the Closing  Date as though
such  representation  or warranty was made on the date hereof and on the Closing
Date,  and any  representation  or warranty made as of a specified  date earlier
than the Closing Date shall have been true and correct in all material  respects
on and as of such specified date.

         8.02  Performance.  Seller shall have  performed and complied with each
agreement, covenant and obligation required by this Agreement to be so performed
or complied with by Purchaser at or before the Closing.

         8.03 Laws.  There  shall not be in effect on the  Closing  Date any Law
restraining,   enjoining  or  otherwise   prohibiting   or  making  illegal  the
consummation of any of the transactions contemplated by this Agreement or any of
the Seller Documents,  or which could reasonably be expected to otherwise result
in a material  diminution of the benefits of the  transactions  contemplated  by
this Agreement or any of the Seller Documents to Purchaser,  and there shall not
be pending or  threatened  on the Closing Date any Action or  Proceeding  or any
other action in, before or by any  Governmental  or Regulatory  Authority  which
could  reasonably be expected to result in the issuance of any such Order or the
enactment, promulgation or deemed applicability to Purchaser or the transactions
contemplated by this Agreement or any of the Seller Documents of any such Law.

         8.04  Regulatory  Consents and Approvals.  All consents,  approvals and
actions of, filings with and notices to any Governmental or Regulatory Authority
necessary to permit Purchaser and Seller to perform their obligations under this
Agreement and any of the Seller  Documents and to  consummate  the  transactions
contemplated  hereby  and  thereby  (a) shall have been duly  obtained,  made or
given, (b) shall be in form and substance reasonably  satisfactory to Purchaser,
(c) shall not be subject to the  satisfaction of any condition that has not been
satisfied  or  waived  and  (d)  shall  be in full  force  and  effect,  and all
terminations or expirations of waiting  periods  imposed by any  Governmental or
Regulatory   Authority  necessary  for  the  consummation  of  the  transactions
contemplated by this Agreement and the Seller Documents shall have occurred.

         8.05 Third Party Consents. All consents (or in lieu thereof waivers) to
the performance by Seller of his obligations under this Agreement and the Seller
Documents or to the  consummation of the  transactions  contemplated  hereby and
thereby as are  required  under any  Contract  to which  Seller is a party or by
which any of the Assets are bound (a) shall have been obtained,  (b) shall be in
form

                                      -24-

<PAGE>



and substance reasonably satisfactory to Purchaser,  (c) shall not be subject to
the  satisfaction of any condition that has not been satisfied or waived and (d)
shall be in full force and effect.

         8.06  Delivery of Assets and  Documents.  At the Closing,  Seller shall
deliver all the Assets to Purchaser and execute and deliver to Purchaser all the
documents required to be delivered by Seller as set forth in Section 2.05(c) and
such  additional  documents  as may be  necessary  in  order to  consummate  the
transactions contemplated by this Agreement and the Seller Documents.

         8.07 Opinion of Counsel.  Purchaser  shall have received the opinion of
Lagerlof,  Senecal,  Bradley,  Gosney & Kruse, LLP, counsel to Seller, dated the
Closing Date, substantially in the form and to the effect of Exhibit I hereto.

         8.08 Tax Status.  Purchaser  shall have  received  evidence of payment,
including tax clearance certificates,  of all sales, use, transfer,  value-added
or other  Taxes  that are to be paid by  Seller  on or  before  the  Closing  in
Pennsylvania and any other applicable jurisdictions.

         8.09 Proceedings.  All proceedings to be taken on the part of Seller in
connection  with  the  transactions  contemplated  by  this  Agreement  and  all
documents  incident  thereto  shall  be  reasonably  satisfactory  in  form  and
substance to  Purchaser,  and Purchaser  shall have received  copies of all such
documents and other  evidences as Purchaser may  reasonably  request in order to
establish  the  consummation  of  such   transactions  and  the  taking  of  all
proceedings in connection therewith.


                                   ARTICLE IX

                        ADDITIONAL POST-CLOSING COVENANTS

         9.01     Further Assurances, Post-Closing Cooperation.

                  (a) At any time or from  time to time  after the  Closing,  at
Purchaser's request and without further consideration,  Seller shall execute and
deliver to  Purchaser  such other  instruments  of sale,  transfer,  conveyance,
assignment and  confirmation,  provide such materials and  information  and take
such other actions as Purchaser may  reasonably  deem  necessary or desirable in
order more  effectively  to  transfer,  convey and assign to  Purchaser,  and to
confirm  Purchaser's  title to, all of the Assets,  and,  to the fullest  extent
permitted by Law, to put Purchaser in actual possession and operating control of
the  Assets and to assist  Purchaser  in  exercising  all  rights  with  respect
thereto,  and  otherwise to cause Seller to fulfill his  obligations  under this
Agreement, including but not limited to, filings with any regulatory agencies to
be made by Seller alone, or by Seller and Purchaser jointly.

                  (b) At any time or from  time to time  after the  Closing,  at
Seller's request and without further consideration,  Purchaser shall execute and
deliver to Seller such other instruments, provide such materials and information
and take such other actions as Purchaser may reasonably


                                      -25-

<PAGE>



deem necessary or desirable in order to give effect to Purchaser's assumption of
the Assumed Liabilities.

                  (c) Effective on the Closing Date,  Seller hereby  constitutes
and appoints  Purchaser the true and lawful attorney of Seller,  with full power
of  substitution,  in the name of Seller or Purchaser,  but on behalf of and for
the benefit of  Purchaser;  (i) to demand and receive  from time to time any and
all the Assets and to make  endorsements  and give receipts and releases for and
in  respect  of the same and any part  thereof;  (ii) to  institute,  prosecute,
compromise and settle any and all Actions or Proceedings that Purchaser may deem
proper in order to collect,  assert or enforce any claim,  right or title of any
kind in or to the Assets,  (iii) to defend or  compromise  any or all Actions or
Proceedings  in respect of any of the  Assets;  and (iv) to do all such acts and
things in relation to the matters set forth in the preceding clauses (i) through
(iii) as Purchaser shall deem  desirable.  Seller hereby  acknowledges  that the
appointment  hereby  made and the powers  hereby  granted  are  coupled  with an
interest and are not and shall not be revocable by it at any time, in any manner
or for any reason.  Seller shall deliver to Purchaser at Closing an acknowledged
power of attorney to the foregoing  effect executed by Seller  substantially  in
the form and to the effect of Exhibit J hereto.  Purchaser  shall  indemnify and
hold  harmless  Seller  and his agents  and  Affiliates  from any and all Losses
caused by or arising out of any breach of Law by  Purchaser  in its  exercise of
such power of attorney.

                  (d) For a period of six (6) years following the Closing,  each
party will  afford the other  party,  its counsel  and its  accountants,  during
normal business hours,  reasonable  access to the books,  records and other data
relating to the Assets in its  possession  with respect to periods  prior to the
Closing and the right to make copies and extracts therefrom,  to the extent that
such access may be  reasonably  required by the  requesting  party in connection
with (i) the preparation of Tax returns,  (ii) the  determination or enforcement
of rights  and  obligations  under this  Agreement,  (iii)  compliance  with the
requirements of any Governmental or Regulatory Authority, (iv) the determination
or enforcement of the rights and obligations of any Indemnified  Party or (v) in
connection  with any actual or  threatened  Action or  Proceeding.  Further each
party  agrees for a period  extending  six years after the  Closing  Date not to
destroy or otherwise dispose of any such books,  records and other data relating
to the Assets  unless such party shall first offer in writing to surrender  such
books,  records and other data to the other party and such other party shall not
agree in writing to take possession thereof during the ten day period after such
offer is made.

                  (e) If, in order  properly to prepare its Tax  returns,  other
documents  or reports  required  to be filed  with  Governmental  or  Regulatory
Authorities or its financial statements or to fulfill its obligations hereunder,
it is necessary that a party be furnished with additional information, documents
or records  relating to the Assets not referred to in paragraph  (c) above,  and
such  information,  documents or records are in the possession or control of the
other  party,  such other  party  shall use its best  efforts to furnish or make
available  such  information,  documents  or records (or copies  thereof) at the
recipient's request,  cost and expense. Any information obtained by either party
in accordance  with this paragraph  shall be held  confidential by such party in
accordance with Section 12.12.


                                      -26-

<PAGE>




                  (f) Notwithstanding anything to the contrary contained in this
section,  if the parties are in an  adversarial  relationship  in  litigation or
arbitration,  the furnishing of information,  documents or records in accordance
with this section shall be subject to applicable rules relating to discovery.

         9.02 FDA  Approvals.  Within  seven days after the Closing  Date,  both
Purchaser and Seller will inform FDA of the ownership  transfer of the Assets if
required by Law.

         9.03 Adverse Drug Experience; Recalls. Seller shall notify Purchaser of
all material  information of which Seller becomes aware concerning side effects,
injury,  toxicity or  sensitivity  reactions  including  incidence  and severity
thereof associated with commercial or clinical uses, studies,  investigations or
tests of any products  relating to the Assets,  whether or not  determined to be
attributable  to such products,  which may constitute an adverse drug experience
with respect to such products under any Laws.  Seller shall notify  Purchaser of
any complaints of which Seller becomes aware concerning any of the Technology or
products relating to the Assets.

         9.04 Delivery of Shares. As soon as practicable after the Closing Date,
upon Seller entering into the Subscription Agreement and the Registration Rights
Agreement  and upon receipt of all  authorizations,  Purchaser  will deliver the
Shares to Seller.

         9.05  Non-Assertion  of  Patent.  Seller  agrees to not  assert the 303
Patent or any other  patent  which has one or more claims  that are  directed to
subject  matter  which  is  disclosed  in the 303  Patent  and  that  refer to a
composition  which  contains a  skin-treating  compound  (as  defined in the 303
Patent)  against  the  Purchaser  of the U.S.  Patent,  or  assignee or licensee
thereof,  or any  customer of the  Purchaser,  assignee  or licensee  (hereafter
collectively  referred  to as "Section  9.05  Person")  in  connection  with the
manufacture,  use or sale by a Section  9.05  Person of a  composition  which is
within  the scope of any claim of the U.S.  Patent  and which is sold only for a
pharmaceutical  industry application,  notwithstanding that such composition may
also  enhance one or more  properties  of skin as  described  in the 303 Patent,
beginning at column 22, line 11.


                                    ARTICLE X

                                 INDEMNIFICATION

         10.01   Survival  of   Representations,   Warranties,   Covenants   and
Agreements.  Notwithstanding  any right of Purchaser  fully to  investigate  the
affairs of Seller or any other party and  notwithstanding  any  knowledge of the
facts determined or determinable by Purchaser  pursuant to such investigation or
right  of  investigation,  Purchaser  has the  right  to  rely  fully  upon  the
representations,  warranties,  covenants and  agreements of Seller  contained in
this Agreement and the Seller Documents.  All such  representations  warranties,
covenants  and  agreements  of  Seller  made in this  Agreement  and the  Seller
Documents  delivered  pursuant  hereto shall  survive the execution and delivery
hereof and the Closing.


                                      -27-

<PAGE>




         10.02  Purchaser's  Indemnified  Liabilities.  Seller  hereby agrees to
indemnify Purchaser, its directors,  officers,  employees, agents and Affiliates
against any liability and will hold each of them harmless from, against and with
respect  to,  and will  reimburse,  any Loss  which  Purchaser,  its  directors,
officers,   employees,   agents  and   Affiliates   incur,   sustain  or  suffer
("Purchaser's Indemnified Liabilities") arising out of or in connection with:

                  (a) Seller's misrepresentation,  breach of any representation,
warranty,  agreement or covenant or  nonfulfillment of or failure to perform any
covenant or  agreement on the part of Seller  contained in this  Agreement or in
the Seller Documents;

                  (b) the Retained Liabilities;

                  (c) any  liability  for Taxes  arising  out of  operations  of
Seller  relating  to the Assets on or prior to the  Closing or arising  from the
sale consummated hereunder;

                  (d) any actual or alleged  liability or  obligation  of Seller
arising  out of the  ownership  or  operation  of the  Assets on or prior to the
Closing;

                  (e) any litigation  matter to which Seller, in connection with
the Assets, or the Assets were subject to on or prior to the Closing; or

                  (f) any liability, loss of any of the Assets or other recovery
resulting from or relating to any litigation or other proceeding commenced by or
involving Conrex,  its officers,  directors,  shareholders or Affiliates,  which
relates to the validity of the sale of the Assets from Conrex to Seller.

         10.03  Seller's  Indemnified  Liabilities.  Purchaser  hereby agrees to
indemnify Seller, his employees, agents and Affiliates against any liability and
will hold each of them  harmless  from,  against  and with  respect to, and will
reimburse,  any Loss which Seller,  his employees,  agents and Affiliates incur,
sustain or suffer  ("Seller's  Indemnified  Liabilities")  arising  out of or in
connection with:

                  (a) Purchaser's    misrepresentation,    breach    of   any
representation,  warranty, agreement or covenant or nonfulfillment of or failure
to perform any covenant or agreement on the part of Purchaser  contained in this
Agreement;

                  (b) the Assumed Liabilities; or

                  (c) any actual or alleged liability or obligation of Purchaser
arising out of the ownership or operation of the Assets after the Closing.

         10.04 Notice and Defense of a Claim. If either party shall be presented
with or have actual notice of a claim against it which gives or may give rise to
an Indemnified Liability, then the party


                                      -28-

<PAGE>



entitled to  indemnification  (the  "Indemnified  Party") shall notify the other
(the "Indemnifying Party") in writing thereof (in accordance with Section 12.01)
within thirty days of notice of a claim,  otherwise the Indemnified  Party shall
waive its right to seek indemnification  hereunder.  The Indemnifying Party may,
at its expense,  vigorously and diligently prosecute, defend and settle any such
claim;  and if the  Indemnifying  Party  assumes such defense it will notify the
Indemnified  Party  thereof,  and thereafter  the  Indemnifying  Party will not,
except as provided  below,  be obligated to pay any expenses of the  Indemnified
Party (including but not limited to, legal fees and  disbursements,  court costs
and the cost of appellate  proceedings) in connection with such claim, provided,
however,  that the  Indemnified  Party may,  at the sole cost and expense of the
Indemnified Party, at any time prior to the Indemnifying Party's delivery of the
notice referred to above, file any motion, answer or other pleadings or take any
other action that the Indemnified  Party reasonably  believes to be necessary or
appropriate to protect its interests.  The  Indemnified  Party will cooperate in
the defense of any such  claim,  and the  Indemnifying  Party will pay any costs
incurred by the Indemnified Party in connection therewith. The Indemnified Party
will not  settle  any  claims  for  which the  Indemnifying  Party may be liable
without  the prior  written  consent of the  Indemnifying  Party  unless (i) the
Indemnified  Party releases the Indemnifying  Party from all of the Indemnifying
Party's  obligations to the Indemnified Party with respect to the claim, or (ii)
the Indemnifying  Party is in default in its obligations under this Section.  In
the case of a  settlement  pursuant to item (ii),  the  Indemnifying  Party will
promptly pay to or in accordance with the instructions of the Indemnified  Party
any amount payable pursuant to such settlement.  Notwithstanding  the foregoing,
if both the Indemnifying Party and the Indemnified Party are named as parties or
subject to any claim and either such party determines with advice of counsel and
in its  reasonable  discretion  that  there  may be one or more  legal  defenses
available to it that are different from or additional to those  available to the
other  party or that a conflict of interest  between  such  parties may exist in
respect of such  claim,  then the  Indemnifying  Party may decline to assume the
defense on behalf of the Indemnified  Party or the Indemnified  Party may retain
the defense on its own behalf,  and, in either such case,  after  notice to such
effect is duly given to the other party (in accordance with Section 12.01),  the
Indemnifying  Party shall be relieved of its obligation to assume the defense on
behalf of the Indemnified Party, but shall be required to pay any legal or other
expenses,   including  without  limitation,   reasonable   attorneys'  fees  and
disbursements, incurred by the Indemnified Party in its defense.


                                   ARTICLE XI

                                   TERMINATION

         11.01  Termination.  This  Agreement  and the Seller  Documents  may be
terminated,  and  the  transactions  contemplated  hereby  and  thereby  may  be
abandoned:

                  (a) at  any  time  before the Closing, by written agreement of
Seller and Purchaser;

                  (b) at any time before the Closing, by Seller or Purchaser, in
the event (i) of a material breach hereof by the  non-terminating  party if such
non-terminating party fails to cure such

                                      -29-

<PAGE>



breach within five Business Days following written  notification  thereof by the
terminating party or (ii) upon written notification of the non-terminating party
by  the  terminating  party  that  the  satisfaction  of  any  condition  to the
terminating  party's  obligations  under this Agreement or the Seller  Documents
becomes  impossible or  impracticable  with the use of  commercially  reasonable
efforts if the  failure of such  condition  to be  satisfied  is not caused by a
breach hereof by the terminating party; or

                  (c) at any time after  March 15,  1999 by Seller or  Purchaser
upon written notification to the non-terminating  party by the terminating party
if the Closing  shall not have  occurred on or before such date and such failure
to  consummate  is not  caused  by a  breach  of this  Agreement  or the  Seller
Documents by the terminating party.

         11.02    Effect of Termination.

                  (a) If this  Agreement  and the Seller  Documents  are validly
terminated  pursuant to Section 11.01,  this Agreement and the Seller  Documents
will  immediately  become  null and void,  and  there  will be no  liability  or
obligation  on the part of  Seller  or  Purchaser  (or any of  their  respective
officers, directors,  employees, agents or other representatives or Affiliates);
provided,  however,  that if this  Agreement is terminated  for any reason other
than Seller's  material  breach or failure to satisfy a condition,  Seller shall
refund the $50,000  due  diligence  deposit  paid by  Purchaser  pursuant to the
letter  agreement  between the parties dated  November 23, 1998. In the event of
any  termination,  the  provisions  with respect to "Expenses" in Section 12.05,
"Entire Agreement" in Section 12.06 and  "Confidentiality" in Section 12.12 will
continue to apply following any such termination.

                  (b)  Notwithstanding  any other provision in this Agreement to
the contrary, upon termination of this Agreement pursuant to Section 11.01(b) or
(c),  Seller will remain liable to Purchaser for any breach of this Agreement by
Seller  existing  at the time of such  termination,  and  Purchaser  will remain
liable to Seller for any breach of this  Agreement by Purchaser  existing at the
time of such  termination,  and  Seller or  Purchaser  may seek  such  remedies,
including  damages and fees of attorneys,  against the other with respect to any
such breach as are provided in this  Agreement or as are otherwise  available at
Law or in equity.


                                   ARTICLE XII

                                  MISCELLANEOUS

         12.01 Notices. All notices, demands or other communications to be given
or delivered  under or by reason of the provisions of this Agreement shall be in
writing and shall be deemed to have been given (a) when delivered  personally to
the   recipient,   (b)  when  sent  to  the   recipient  by  telecopy   (receipt
electronically confirmed by sender's telecopy machine) if during normal business
hours of the recipient, otherwise on the next Business Day, (c) one Business Day
after the date when sent to the recipient by reputable  express  courier service
(charges  prepaid) or (d) seven  Business Days after the date when mailed to the
recipient by certified or registered mail, return receipt requested and postage

                                      -30-

<PAGE>



prepaid.  Such notices,  demands and other communications will be sent to Seller
and to Purchaser at the addresses indicated below:


   If to Purchaser:              Bentley Pharmaceuticals, Inc
                                 Two Urban Centre
                                 Suite 400
                                 4830 West Kennedy Blvd.
                                 Tampa, Florida 33609
                                 Attention: James R. Murphy
                                 Facsimile No.: (813) 282-8941

   With a copy (which shall      Parker, Chapin, Flattau & Klimpl, LLP
   not constitute notice) to:    1211 Avenue of the Americas
                                 New York, New York 10036
                                 Attention: Jordan A. Horvath and Mark S. Hirsch
                                 Facsimile No.: (212) 704-6288

   If to Seller:                 Yungtai Hsu
                                 

                                 Facsimile No.: 

   With a copy (which shall not
   constitute notice) to:        Lagerlof, Senecal, Bradley, Gosney & Kruse, LLP
                                 301 North Lake Avenue, 10th Floor
                                 Pasadena, CA  91101
                                 Attention:  Timothy J. Gosney
                                 Facsimile No.: (626) 793-5900


or to such other address as any party hereto may,  from time to time,  designate
in writing delivered pursuant to the terms of this Section.

         12.02  Amendments.   The  terms,  provisions  and  conditions  of  this
Agreement  may not be changed,  modified  or amended in any manner  except by an
instrument in writing duly executed by both parties hereto.

         12.03 Binding  Effect;  Assignment.  This  Agreement and the rights and
obligations  hereunder are assignable by Purchaser and any such assignment shall
be binding in all  respects on Seller,  as if Seller had sold all or part of the
Assets directly to the assignee.  This Agreement shall be binding upon and shall
inure to the benefit of the parties hereto and their  respective  successors and
permitted assigns.

                                      -31-

<PAGE>




         12.04  Announcements.  All press  releases,  notices to  customers  and
suppliers and other announcements prior to the Closing Date with respect to this
Agreement and the Seller  Documents and the  transactions  contemplated  by this
Agreement  and the Seller  Documents  shall be  approved by both  Purchaser  and
Seller prior to the issuance  thereof,  which approval shall not be unreasonably
withheld or delayed;  provided that any party may make any public  disclosure it
believes  in good  faith is  required  by law or  regulation  (in which case the
disclosing  party shall  advise the other party prior to making such  disclosure
and provide such other party an opportunity to review the proposed disclosure).

         12.05 Expenses.  Except as otherwise set forth in this Agreement,  each
party to this  Agreement  shall  bear all of its  legal,  accounting  and  other
expenses  incurred by it or on its behalf in  connection  with the  transactions
contemplated  by  this  Agreement,   whether  or  not  such   transactions   are
consummated.

         12.06  Entire  Agreement.  This  Agreement  and  the  Seller  Documents
constitute the entire  agreement  between the parties hereto with respect to the
subject matter hereof and supersede and are in full substitution for any and all
prior  agreements,  commitments,  discussions,  negotiations,   arrangements  or
understandings  between the parties relating to such subject matter,  including,
but not limited to, any letters of intent  between the parties prior to the date
hereof.  The Seller  Documents,  including  but not limited to the  Exhibits and
Schedules to this Agreement,  are hereby incorporated and made a part hereof and
are an integral part of this Agreement.

         12.07  Descriptive  Headings.  The descriptive  headings of the several
sections of this  Agreement  are  inserted  for  convenience  only and shall not
control or affect the meaning or construction of any of the provisions hereof.

         12.08  Counterparts.  This  Agreement  may be executed in any number of
counterparts,  each of  which  shall be  deemed  an  original,  but all of which
together shall constitute one and the same instrument.

         12.09 Governing Law; Jurisdiction. This agreement shall be governed by,
and  interpreted  and enforced in accordance  with, the laws of the State of New
York without regard to principles of choice of law or conflict of laws.

         12.10    Arbitration of Disputes

                  (a) If any  controversy or dispute arises under,  out of or in
relation to any of the provisions  hereof,  such controversy or dispute shall be
submitted  for  arbitration  in New  York,  New  York  before  a panel  of three
arbitrators,  one of which  shall  be  selected  by the  party  initiating  such
arbitration,  one of which shall be selected by the other party and the third of
which (the  "Third  Arbitrator")  shall be selected  by the two  arbitrators  so
selected; provided, however, that in the event that such other arbitrators shall
not agree on the selection of the Third Arbitrator, the Third Arbitrator

                                      -32-

<PAGE>



shall be selected by the American  Arbitration  Association located in New York,
New York. Any dispute or controversy submitted to arbitration in accordance with
the provisions of this Section 12.10 shall be determined by such  arbitrators in
accordance  with the Commercial  Arbitration  Rules of the American  Arbitration
Association then existing.

                  (b) The arbitrators may award any relief which they shall deem
proper in the circumstances,  without regard to the relief which would otherwise
be  available  to any  party  in a court  of law or  equity  including,  without
limitation, an award of money damages,  specific performance,  injunctive relief
and/or  declaratory  relief,  however,  such an award may not  include  punitive
damages.  The award and  findings of the  arbitrators  shall be  conclusive  and
binding  upon all of the  parties  hereto,  whether  or not all  parties  hereto
participate in the  arbitration  proceeding,  and judgment upon the award may be
entered  in any court of  competent  jurisdiction  upon the  application  of any
party. The parties hereby agree that such courts of competent jurisdiction shall
include,  but not be limited to, the courts located in any jurisdiction in which
the party against whom such judgment is being enforced maintains any assets.

                  (c) The prevailing  party in the arbitration  proceeding shall
be entitled  to recover  from the other party its  reasonable  attorneys'  fees,
costs and expenses  incurred in the proceeding  and in any subsequent  action to
enforce or collect upon the decision rendered in the arbitration proceeding.

                  (d)  Notwithstanding  the foregoing,  the parties  reserve the
right to seek and obtain injunctive  relief,  whether in the form of a temporary
restraining order, preliminary injunction,  injunction to enforce an arbitration
award,  or other order of similar  import,  from the  federal  and state  courts
located  in New  York,  New York  prior to,  during,  or after  commencement  or
prosecution  or  arbitration  proceedings of the final decision and award of the
arbitrators; provided, however, that such preliminary injunctive relief shall be
subject to final arbitral decisions.

                  (e) Each party hereby consents and agrees that the federal and
state courts located in New York,  New York each shall have  exclusive  personal
jurisdiction and proper venue with respect to any such action seeking injunctive
or similar relief hereunder.  In any dispute between the parties,  neither party
will raise, and each party hereby expressly waives,  any objection or defense to
any such court as an  inconvenient  forum.  Each party  hereby  waives  personal
service of any summons,  complaint or other  process,  which may be delivered by
any of the means permitted for notices under Section 12.01 hereof

         12.11 Severability. In the event that any one or more of the provisions
contained in this Agreement or in any other instrument referred to herein shall,
for any reason, be held to be invalid,  illegal or unenforceable in any respect,
then to the maximum  extent  permitted by law,  such  invalidity,  illegality or
unenforceability  shall not affect any other  provision of this Agreement or any
other such instrument. Furthermore, in lieu of any such invalid or unenforceable
term or provision, the parties hereto intend that there shall be added as a part
of  this  Agreement  a  provision  as  similar  in  terms  to  such  invalid  or
unenforceable provision as may be possible and be valid and enforceable.

                                      -33-

<PAGE>




         12.12 Confidentiality. Seller and Purchaser agree to keep, and to cause
each  of  their   Affiliates,   directors,   officers  and  employees  to  keep,
confidential any and all confidential information of the other party that either
receives in the course of performing its obligations hereunder (unless compelled
by judicial or  administrative  process and except that such  information may be
shared,  on a confidential  basis,  with the party's attorneys and auditors) and
will  not,  without  the  other  party's  written  consent,   use  any  of  such
confidential  information  except as reasonably  necessary to perform its duties
under this or another of its  agreements  with the other party (for  purposes of
this Agreement,  "confidential  information"  includes any and all trade secrets
(including information relating to the Technology,  the Patents and the Business
Information),  financial  information  not  disclosed to the general  public and
other proprietary information disclosed in the course of the negotiation of this
Agreement and  Purchaser's  due diligence  investigation).  Furthermore,  Seller
agrees to refrain from,  either alone or in  conjunction  with any other Person,
directly or indirectly through his present or future  Affiliates,  and agrees to
cause his  Affiliates  and  employees  to refrain from  disclosing  or using any
Business  Information  relating to the Assets or the  Technology  or any client,
customer or supplier of the Assets or the Technology.  Upon  termination of this
Agreement,  each party will return,  and will cause its  Affiliates,  directors,
officers and employees to return, to the other party, all original documents and
copies of the confidential information which are in its possession.


                                      -34-

<PAGE>


                  IN WITNESS  WHEREOF,  Seller and  Purchaser  have executed and
delivered this Agreement as of the day and year first written above.

                                        /s/ Yungtai Hsu
                                        -------------------------------------
                                        Yungtai Hsu, in his personal capacity


                                        BENTLEY  PHARMACEUTICALS, INC.


                                        By:  /s/ James R. Murphy
                                             -----------------------------------
                                 
                                             James R. Murphy, Chairman and Chief
                                             Executive Officer


                                      -35-

                             SUBSCRIPTION AGREEMENT
                             ----------------------

                          BENTLEY PHARMACEUTICALS, INC.
                          -----------------------------

Bentley Pharmaceuticals, Inc.
Two Urban Centre, Suite 400
4890 West Kennedy Blvd.
Tampa, Florida 33609

                                                               February 11, 1999

Dear Sir or Madam:

                  Upon the  terms  and  subject  to the  conditions  of an Asset
Purchase  Agreement,  dated  February 1, 1999  effective as of December 31, 1998
(the "Asset Purchase  Agreement"),  between Bentley  Pharmaceuticals,  Inc. (the
"Company")  and Yungtai Hsu ("Hsu"),  in which Hsu agreed to sell certain of his
assets to the Company,  Hsu has agreed to accept as part of the  Purchase  Price
(as defined in the Asset  Purchase  Agreement) (a) 225,807 shares (the "Shares")
of common stock,  $0.02 par value per share (the "Common Stock") of the Company,
and (b) a warrant to purchase  450,000  shares of Common  Stock (the  "Warrant",
collectively  the Shares  and the  Warrant,  the  "Securities").  Therefore,  in
consideration  of the premises  and the mutual  covenants  contained  herein and
other good and valuable consideration,  the receipt and sufficiency of which are
hereby acknowledged, Hsu hereby agrees to:

                  1.  Subscription.  Hsu  hereby  applies to  subscribe  for the
Securities.  Once this Agreement is executed by both Hsu and the Company,  it is
intended to create a binding  agreement between Hsu and the Company with respect
to the terms and conditions described below.

                  2.  Representations  and Warranties of Hsu. Hsu  acknowledges,
represents, warrants and agrees as follows:

                                    (a)  Authorization.  Hsu has full  power and
legal  capacity to execute and deliver this  Agreement.  This Agreement has been
duly  executed and  delivered by Hsu and,  assuming the  execution  and delivery
hereof and thereof by the Company,  will constitute the legal, valid and binding
obligations of Hsu, enforceable against Hsu in accordance with its terms, except
as the same may be limited by applicable bankruptcy, insolvency, reorganization,
moratorium or other similar laws affecting the rights of creditors generally and
the availability of equitable remedies.


<PAGE>



                                    (b)   Accredited   Investor.   Hsu   is   an
accredited  investor (as defined in Rule 501 of  Regulation D  ("Regulation  D")
promulgated  under the Securities  Act of 1933, as amended (the "Act").  Hsu has
such knowledge and experience in financial and business matters as to be capable
of evaluating  the merits and risks of, and bearing the economic  risks entailed
by, an investment  in the Company and of protecting  his interests in connection
with  this  transaction.  Hsu  recognizes  that his  investment  in the  Company
involves  certain  risks  which  are set  forth  in the  Company's  Registration
Statement on Form S-3 (SEC File No. 333-28593,  the  "Registration  Statement" )
declared  effective by the Securities  and Exchange  Commission on June 10, 1997
and any amendments thereto.

                                    (c) Due  Diligence.  Hsu has received a copy
of such  documents as requested by him, has carefully  reviewed such  documents,
has had the opportunity to obtain any additional information necessary to verify
the accuracy of the  information  contained in such documents and has been given
the  opportunity  to meet with  representatives  of the Company and to have them
answer any questions and provide any additional  information regarding the terms
and conditions of this  particular  investment  deemed  relevant by Hsu, and all
such  questions have been answered and requested  information  provided to Hsu's
full satisfaction. Among the documents received and reviewed by Hsu are: (i) the
Company's  Annual Report on Form 10-K for the year ended December 31, 1997; (ii)
the Company's  Quarterly  Reports on Form 10-Q for the quarters  ended March 31,
1998,  June 30, 1998 and  September 30, 1998 (such  documents  are  collectively
referred  to in  this  Agreement  as the  "Exchange  Act  Reports");  (iii)  the
Registration  Statement and (iv) a  Registration  Rights  Agreement  between the
Company  and Hsu with  respect to the  Shares,  dated as of the date hereof (the
"Registration   Rights  Agreement.")  In  making  his  decision  to  accept  the
Securities as part of the Purchase Price,  Hsu has relied solely upon his review
of  the  documents   referred  to  above  and  this  Agreement  and  independent
investigations made by him or his representatives.

                                    (d) No Legal  Advice from the  Company.  Hsu
acknowledges  that he has had the  opportunity  to review this Agreement and the
transactions  contemplated  by this Agreement with his own legal counsel and tax
advisors.  Except for any statements or  representations  of the Company made in
this  Agreement,  in the  Exchange  Act Reports and in the  Registration  Rights
Agreement,  Hsu is relying  solely on such  counsel and  advisors and not on any
statements or  representations  of the Company or any of its  representative  or
agents for legal, tax or investment advice with respect to this investment,  the
transactions  contemplated  by  this  Agreement  or the  securities  laws of any
jurisdiction.

                                    (e) Not an Affiliate. Hsu is not an officer,
director or "affiliate"  (as that term is defined in Rule 405 of the Act) of the
Company.

                                    (f)   Reliance   on   Representations    and
Warranties.  Hsu  understands  that the Securities are being offered and sold to
him in  reliance  on  specific  provisions  of United  States  federal and state
securities laws and that the Company is relying upon the truth and

                                       -2-

<PAGE>



accuracy of the  representations,  warranties,  agreements,  acknowledgments and
understandings  of Hsu set forth in this  Agreement  in order to  determine  the
applicability of such provisions.

                                    (g) No  Registration.  Hsu understands  that
the sale of the  Securities has not been  registered  under the Act, in reliance
upon an  exemption  therefrom  by  virtue  of  Section  4(2)  and  Regulation  D
promulgated  under the Act. Hsu  understands  that the  Securities  must be held
indefinitely and may not be offered, transferred,  resold, pledged, hypothecated
or other wise disposed of until the sale or other transfer thereof is registered
under the Act,  pursuant to the terms and conditions of the Registration  Rights
Agreement or unless an  exemption  from such  registration  is available at that
time. Hsu is aware that he will be required to bear the financial  risks of this
investment  for an indefinite  period of time unless  transferred  in accordance
with the above. Hsu covenants that he will not knowingly make any sale, transfer
or other  disposition of the Securities or any interest  therein in violation of
the Act,  the  Exchange Act of 1934,  as amended,  or the rules and  regulations
promulgated under either of said Acts.

                                    (h) Investment  Intent. Hsu is acquiring the
Securities  solely for his own account as  principal  and not with a view to the
distribution  thereof to or for the benefit or account of any other  person,  in
whole or in part,  and no other  person  has a  direct  or  indirect  beneficial
interest in such  Securities.  Hsu  understands and agrees that he must bear the
economic risk of his investment in the  Securities  for an indefinite  period of
time.  Hsu will not take any short  position in the Securities and not otherwise
engage in any hedging transactions such as option writing, equity swaps or other
types of derivative transactions with respect to the Securities.

                                    (i) Additional  Transfer  Restrictions.  Hsu
understands and agrees that, in addition to the  restrictions  set forth in this
Agreement,  the following  restrictions  and  limitations  are applicable to his
purchase  and any resales,  pledges,  hypothecations  or other  transfers of the
Securities:

                                        (i) The following legend  reflecting all
applicable   restrictions  will  be  placed  on  any   certificate(s)  or  other
document(s)  evidencing  the  Securities  and Hsu must comply with the terms and
conditions   set  forth  in  such  legends   prior  to  any  resales,   pledges,
hypothecations or other transfers of the Securities:

                                        "THE  SECURITIES   REPRESENTED  BY  THIS
                                        CERTIFICATE  HAVE  NOT  BEEN  REGISTERED
                                        UNDER  THE  SECURITIES  ACT OF 1933,  AS
                                        AMENDED (THE "ACT") OR APPLICABLE  STATE
                                        SECURITIES  LAWS.  THE  SECURITIES  HAVE
                                        BEEN  ACQUIRED FOR  INVESTMENT  PURPOSES
                                        ONLY AND MAY NOT BE  OFFERED  FOR  SALE,
                                        SOLD, HYPOTHECATED, ASSIGNED, PLEDGED OR
                                        OTHERWISE TRANSFERRED IN THE


                                       -3-

<PAGE>



                                        ABSENCE  OF  AN  EFFECTIVE  REGISTRATION
                                        STATEMENT  COVERING THE SECURITIES UNDER
                                        THE ACT OR APPLICABLE  STATE  SECURITIES
                                        LAWS,   OR   AN   OPINION   OF   COUNSEL
                                        SATISFACTORY    TO   THE   ISSUER   THAT
                                        REGISTRATION  IS NOT REQUIRED  UNDER THE
                                        ACT OR APPLICABLE STATE SECURITIES LAWS.

                                        (ii)  Stop  transfer  instructions  have
been or will be placed on any  certificates  or other  documents  evidencing the
Securities so as to restrict the resale, pledge, hypothecation or other transfer
thereof in accordance with the provisions hereof.

                                    (j)   Termination   of   Restrictions.   The
restrictions  described  in  Section 2 hereof  upon the  transferability  of the
Securities  shall cease and terminate as to any particular  Securities (i) when,
in the  opinion  of  Parker  Chapin  Flattau  &  Klimpl,  LLP or  other  counsel
reasonably  acceptable to the Company,  such restrictions are no longer required
in order to assure  compliance  with the Act or (ii)  when,  in the  opinion  of
Parker Chapin Flattau & Klimpl,  LLP or other counsel  reasonably  acceptable to
the  Company,  such  Securities  shall  have  been  registered  under the Act or
transferred  in reliance upon the exemption  afforded by Section 4(1) of the Act
by virtue of Rule 144.

                                    (k) Indemnification. Hsu shall indemnify and
hold  harmless the Company and each officer,  director or control  person of any
such entity,  who is or may be a party or is or may be  threatened  to be made a
party to any  threatened,  pending  or  completed  action,  suit or  proceeding,
whether  civil,  criminal,  administrative  or  investigative,  by  reason of or
arising  from (i) any actual or alleged  misrepresentation  or  misstatement  of
facts or omission to  represent or state facts made or alleged to have been made
by Hsu to the  Company,  (or  its  officers,  directors,  employees,  agents  or
representatives),  or omitted or alleged to have been omitted by Hsu, concerning
Hsu, or Hsu's  authority to invest or financial  position in connection with the
offering or sale of the Securities, or (ii) any breach of warranty or failure to
comply  with  any  covenant  contained  in this  Agreement,  including,  without
limitation,  any such misrepresentation,  misstatement or omission, or breach of
any warranty or covenant,  contained  herein or any other document  submitted by
Hsu,  against  losses,  liabilities  and expenses for which the Company,  or its
officers,  directors  or  control  persons  has not  otherwise  been  reimbursed
(including attorneys' fees,  judgments,  fines and amounts paid in settlement in
matters  settled in accordance  with the  provision of the following  paragraph)
incurred  by the  Company,  or such  officer,  director  or  control  person  in
connection with such action,  suit or proceeding;  provided,  however,  that Hsu
will not be liable in any such case for losses, claims, damages,  liabilities or
expenses  that a court of  competent  jurisdiction  shall  have found in a final
judgment  to  have  arisen  primarily  from  the  gross  negligence  or  willful
misconduct of the Company or the party claiming a right to indemnification.


                                       -4-

<PAGE>



                  In case any  proceeding  shall  be  instituted  involving  any
person  with  respect  to  whom  indemnity  may  be  sought,  such  person  (the
"Indemnified Party") shall promptly notify Hsu, and Hsu, upon the request of the
Indemnified  Party,   shall  retain  counsel  reasonably   satisfactory  to  the
Indemnified  Party to  represent  the  Indemnified  Party and any others Hsu may
designate in such proceedings and shall pay as incurred the fees and expenses of
such counsel related to such proceeding. In any such proceeding, any Indemnified
Party shall have the right to retain its own counsel at its own expense,  except
that Hsu shall pay as incurred the fees and expenses of counsel  retained by the
Indemnified Party in the event that (i) Hsu and the Indemnified Party shall have
mutually  agreed to the  retention of such counsel or, (ii) the named parties to
any such proceeding  (including any impleaded  parties) include both Hsu and the
Indemnified  Party and  representation of both parties by the same counsel would
be  inappropriate,  in the reasonable  opinion of the Indemnified  Party, due to
actual or potential  differing  interests  between them. Hsu shall not be liable
for any settlement of any proceeding  effected without its written consent,  but
if settled with such consent or if there be a final  judgment for the plaintiff,
Hsu agrees to indemnify  the  Indemnified  Party to the extent set forth in this
Agreement.

                  In the event a claim for  indemnification  as described herein
is determined to be  unenforceable  by a final  judgment of a court of competent
jurisdiction, then Hsu shall contribute to the aggregate losses, claims, damages
or  liabilities  to  which  the  Company  or its  officers,  directors,  agents,
employees or controlling persons may be subject in such amount as is appropriate
to reflect the relative  benefits  received by each of the  undersigned  and the
party seeking  contribution  on the one hand and the relative  faults of Hsu and
the party seeking  contribution on the other, as well as any relevant  equitable
considerations.

                  The provisions of this Agreement  relating to  indemnification
and  contribution  shall  survive  termination  of this  Agreement  and shall be
binding upon any successors or assigns of Hsu.

                  3.  Representations and Warranties of the Company. The Company
acknowledges, represents, warrants and agrees as follows:

                                    (a)  Organization  and  Authorization.   The
Company is a corporation  duly organized,  validly existing and in good standing
under the laws of the state of Florida  and has all req uisite  corporate  power
and authority to own and operate its  properties  and assets and to carry on its
business as currently  conducted.  The Company is not in default or violation of
any material  term or provision of its Articles of  Incorporation  or Bylaws nor
will the consummation of the  transactions  contemplated by this Agreement cause
any such default or violation. The Company has all requisite corporate power and
authority to enter into this Agreement,  to sell the Securities hereunder and to
carry out and perform its obligations  under the terms of this Agreement subject
to the above.  This Agreement is a valid and binding  obligation of the Company,
enforceable in accordance with its terms.

                                    (b)  Capitalization.  The authorized capital
stock of the Company consists of 35,000,000 shares of Common Stock and 2,000,000
shares of Preferred Stock, par value $.02 per

                                       -5-

<PAGE>



share.  Upon issuance of the Securities  pursuant to the terms of this Agreement
and  payment  therefor  pursuant  to the  terms of an Asset  Purchase  Agreement
between Hsu and the Company, the Shares will be duly authorized, validly issued,
fully paid and nonassessable and the Warrant will be duly authorized and validly
issued. Upon issuance, the Shares will not be subject to any preemptive or other
preferential rights or similar statutory or contractual rights.

                  The Closing shall take place as soon as practicable  after (i)
due  execution  by Hsu  and  acceptance  by the  Company  of  this  Subscription
Agreement and (ii) the closings as contemplated by the Asset Purchase  Agreement
and  the  Asset  Purchase  Agreement  between  Hsu  and  Conrex   Pharmaceutical
Corporation.

                  4.       Miscellaneous.

                                    (a) Notices.  All notices,  demands or other
communications  to be given or delivered under or by reason of the provisions of
this  Agreement  shall be in writing  and shall be deemed to have been given (a)
when delivered  personally to the  recipient,  (b) when sent to the recipient by
telecopy  (receipt  electronically  confirmed by sender's  telecopy  machine) if
during normal  business hours of the  recipient,  otherwise on the next Business
Day ("Business Day" means a day other than Saturday,  Sunday or any day on which
banks  located in the State of New York are  authorized  or obligated to close),
(c) one  Business  Day after the date when sent to the  recipient  by  reputable
express courier service  (charges  prepaid) or (d) seven Business Days after the
date when mailed to the  recipient  by  certified  or  registered  mail,  return
receipt  requested  and  postage  prepaid.  Such  notices,   demands  and  other
communications will be sent to Hsu and to the Company at the addresses indicated
below.

                           If to Hsu, to:

                           Yungtai Hsu   


                           Facsimile No.: 

                           With a copy (which shall not constitute notice) to:

                           Lagerlof, Senecal, Bradley, Gosney & Kruse, LLP
                           301 North Lake Avenue, 10th Floor
                           Pasadena, CA  91101
                           Attention:  Timothy J. Gosney
                           Facsimile No.: (626) 793-5900


                                       -6-

<PAGE>



                           If to the Company, to:

                           Bentley Pharmaceuticals, Inc.
                           Two Urban Centre, Suite 400
                           4890 West Kennedy Blvd.
                           Tampa, Florida 33609
                           Attention:  James R. Murphy
                           Facsimile No.:  (813) 282-8941


                           With a copy (which shall not constitute notice) to:

                           Parker Chapin Flattau & Klimpl, LLP
                           1211 Avenue of the Americas
                           New York, New York 10036
                           Attention: Mark S. Hirsch
                                      Jordan A. Horvath
                           Facsimile No.: (212) 704-6288

                                    (b) Assignment;  Benefit. This Agreement may
not be assigned by Hsu without the prior written  consent of the Company and any
assignment without such consent shall be void. This Agreement may be assigned by
the Company to any person or entity which purchases all or substantially  all of
the stock or assets of the Company or is the  successor to the Company by merger
or consolidation.  This Agreement shall be binding upon and inure to the benefit
of the respective successors and permitted assigns of the Company and of Hsu.

                                    (c)   Severability.    The   invalidity   or
unenforceability  of any  provisions  of this  Agreement  shall not  affect  the
validity or  enforceability  of any other provision of this  Agreement,  each of
which shall remain in full force and effect.

                                    (d)   Amendments.   This  Agreement  may  be
amended,  supplemented or modified, and any provision hereof may be waived, only
pursuant to a written  instrument  making  specific  reference to this Agreement
signed by each of the parties hereto.

                                    (e)  Counterparts.  This  Agreement  may  be
executed  in any  number  of  counterparts,  each of which  shall be  deemed  an
original,  but  all  of  which  together  shall  constitute  one  and  the  same
instrument.

                                    (f) Governing Law. This  Agreement  shall be
governed by and construed in  accordance  with the laws of the State of New York
applicable to a contract  executed and  performed in such State  without  giving
effect  to the  conflicts  of  laws  principles  thereof,  except  that if it is
necessary in any other  jurisdiction to have the law of such other  jurisdiction
govern this

                                       -7-

<PAGE>



Agreement in order for this  Agreement to be effective in any respect,  then the
laws of such other jurisdiction shall govern this Agreement to such extent.

                                    (g) Arbitration of Disputes

                                        (i) If any controversy or dispute arises
under, out of or in relation to any of the provisions  hereof,  such controversy
or dispute shall be submitted  for  arbitration  in New York,  New York before a
panel of  three  arbitrators,  one of  which  shall  be  selected  by the  party
initiating such  arbitration,  one of which shall be selected by the other party
and the third of which (the  "Third  Arbitrator")  shall be  selected by the two
arbitrators so selected;  provided,  however,  that in the event that such other
arbitrators shall not agree on the selection of the Third Arbitrator,  the Third
Arbitrator shall be selected by the American Arbitration  Association located in
New York,  New York.  Any dispute or  controversy  submitted to  arbitration  in
accordance  with the  provisions  of this Section  shall be  determined  by such
arbitrators in accordance with the Commercial  Arbitration Rules of the American
Arbitration Association then existing.

                                        (ii)  The   arbitrators  may  award  any
relief which they shall deem proper in the circumstances,  without regard to the
relief  which would  otherwise  be  available  to any party in a court of law or
equity  including,  without  limitation,  an award of  money  damages,  specific
performance, injunctive relief and/or declaratory relief, however, such an award
may not include  punitive  damages.  The award and  findings of the  arbitrators
shall be conclusive and binding upon all of the parties  hereto,  whether or not
all parties hereto participate in the arbitration proceeding,  and judgment upon
the  award  may be  entered  in any  court of  competent  jurisdiction  upon the
application of any party. The parties hereby agree that such courts of competent
jurisdiction  shall  include,  but not be limited to, the courts  located in any
jurisdiction  in which the party  against whom such  judgment is being  enforced
maintains any assets.

                                        (iii)  The   prevailing   party  in  the
arbitration  proceeding  shall be entitled  to recover  from the other party its
reasonable attorneys' fees, costs and expenses incurred in the proceeding and in
any  subsequent  action to enforce or collect upon the decision  rendered in the
arbitration proceeding.

                                        (iv) Notwithstanding the foregoing,  the
parties reserve the right to seek and obtain injunctive  relief,  whether in the
form of a temporary  restraining order,  preliminary  injunction,  injunction to
enforce an arbitration award, or other order of similar import, from the federal
and state  courts  located  in New York,  New York  prior to,  during,  or after
commencement or prosecution or arbitration proceedings of the final decision and
award of the arbitrators;  provided,  however, that such preliminary  injunctive
relief shall be subject to final arbitral decisions.

                                        (v)  Each  party  hereby   consents  and
agrees  that the  federal and state  courts  located in New York,  New York each
shall have exclusive personal  jurisdiction and proper venue with respect to any
such action seeking injunctive or similar relief

                                       -8-

<PAGE>


hereunder.  In any dispute  between the parties,  neither party will raise,  and
each party hereby expressly  waives,  any objection or defense to any such court
as an  inconvenient  forum.  Each party hereby  waives  personal  service of any
summons,  complaint or other process, which may be delivered by any of the means
permitted for notices under Section 6(a) hereof.

                                    (h)   Entire   Agreement.   This   Agreement
constitutes the entire agreement between Hsu and the Company with respect to the
subject matter hereof.



                                            /s/  Yungtai Hsu
                                           -------------------------------------
                                           Yungtai Hsu, in his personal capacity


ACCEPTED AND AGREED:

BENTLEY PHARMACEUTICALS, INC.


By:  /s/ James R. Murphy
     ------------------------------------                               
     James R. Murphy, Chairman, President
     and Chief Executive Officer


                                       -9-

                          REGISTRATION RIGHTS AGREEMENT
                          -----------------------------


                  THIS REGISTRATION  RIGHTS AGREEMENT,  is made and entered into
as of  February  11,  1999  between  BENTLEY  PHARMACEUTICALS,  INC.,  a Florida
corporation (the "Company") and Yungtai Hsu ("Hsu").

                  WHEREAS,  upon the terms and subject to the  conditions  of an
Asset Purchase Agreement,  dated February 1, 1999,  effective as of December 31,
1998 (the "Asset Purchase Agreement"), between the Company and Hsu, in which Hsu
agreed to sell  certain of his assets to the  Company,  Hsu has agreed to accept
225,807  shares (the  "Shares") of common stock,  $0.02 par value per share (the
"Common  Stock") of the Company as part of the Purchase Price (as defined in the
Asset Purchase Agreement);

                  WHEREAS,  to induce  Hsu to accept  the  Shares as part of the
Purchase Price,  the Company has agreed to provide certain  registration  rights
under the  Securities  Act of 1933,  as amended,  and the rules and  regulations
thereunder,  or any similar successor statute  (collectively,  the "Act"),  with
respect to the Shares;

                  WHEREAS,  as of the date hereof,  Hsu and the Company  entered
into a  Subscription  Agreement  with  respect to the Shares (the  "Subscription
Agreement");

                  NOW,  THEREFORE,  in  consideration  of the  premises  and the
mutual covenants contained herein and other good and valuable consideration, the
receipt and  sufficiency of which are hereby  acknowledged,  the Company and Hsu
hereby agree as follows:

                  1.       Definitions.

                  (a) As used in this Agreement,  the following terms shall have
the following meanings:

                  (i) "Register,"  "Registered," and  "Registration"  refer to a
registration  effected  by  preparing  and filing a  Registration  Statement  in
compliance with the Act and the declaration or ordering of effectiveness of such
Registration  Statement by the United States Securities and Exchange  Commission
(the "SEC").

                  (ii) "Registrable Securities" means the Shares.

                  (iii) "Registration  Statement" means a registration statement
of the Company under the Act,  including any amendments or  supplements  thereto
and prospectuses contained therein.

<PAGE>



                  (iv) "Stockholder"  means Hsu and any permitted  transferee or
assignee  who agrees to become  bound by the  provisions  of this  Agreement  in
accordance with Section 9 hereof.

                  (b)  Capitalized  terms used herein and not otherwise  defined
herein  shall  have the  respective  meanings  set forth in the  Asset  Purchase
Agreement.

                  2.       Restrictions on Transfer.

                  (a) The Stockholder acknowledges and understands that prior to
the  registration of the Shares as provided  herein,  the Shares are "restricted
securities" as defined in Rule 144 promulgated  under the Act ("Rule 144").  The
Stockholder understands that the Shares may not be offered, transferred, resold,
pledged,  hypothecated or otherwise disposed of in the absence of (i) an opinion
of Parker Chapin Flattau & Klimpl, LLP or other counsel reasonably acceptable to
the Company that such transfer may be made without registration under the Act or
(ii) an  opinion  of  Parker  Chapin  Flattau  &  Klimpl,  LLP or other  counsel
reasonably acceptable to the Company that the Shares have been Registered.

                  (b) The Stockholder  acknowledges  that the Company has issued
the Shares to the Stockholder  pursuant to an exemption from registration  under
the  Act.  Stockholder  represents  that  (i) he has  acquired  the  Shares  for
investment  and  without  any view  toward  distribution  of any of  Registrable
Securities  to any other person,  (ii) he will not sell or otherwise  dispose of
the Shares except in compliance with the registration  requirements or exemption
provisions  under the Act and (iii) before any sale or other  disposition of any
of the Shares other than in a sale registered  under the Act or pursuant to Rule
144 or 144A (or any similar  provisions then in force) under the Act (unless the
Company  shall  have been  advised  by  counsel  that the sale does not meet the
requirements  of Rule 144 or Rule 144A,  as the case may be, for such sale),  he
will  deliver  to the  Company  an opinion  of  counsel,  in form and  substance
reasonably  satisfactory to the Company, to the effect that such registration is
unnecessary.

                  (c) Each instrument or certificate  evidencing or representing
the Shares, and any certificate issued in exchange therefor or transfer thereof,
shall bear legends substantially in the following form:

                  "THE SECURITIES  REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN
                  REGISTERED  UNDER THE  SECURITIES ACT OF 1933, AS AMENDED (THE
                  "ACT") OR APPLICABLE  STATE  SECURITIES  LAWS.  THE SECURITIES
                  HAVE BEEN ACQUIRED FOR INVESTMENT PURPOSES ONLY AND MAY NOT BE
                  OFFERED FOR SALE,  SOLD,  HYPOTHECATED,  ASSIGNED,  PLEDGED OR
                  OTHERWISE   TRANSFERRED   IN  THE  ABSENCE  OF  AN   EFFECTIVE
                  REGISTRATION  STATEMENT  COVERING THE SECURITIES UNDER THE ACT
                  OR APPLICABLE  STATE SECURITIES LAWS, OR AN OPINION OF COUNSEL
                  SATISFACTORY TO THE ISSUER THAT

                                       -2-

<PAGE>



                  REGISTRATION IS NOT REQUIRED UNDER THE ACT OR APPLICABLE STATE
                  SECURITIES LAWS.

                  3.       Registration.

                  (a) If at any  time or from  time to time  following  the date
hereof,  the  Company  shall  determine  to  register  any  distribution  of its
securities with the SEC, either for its own account or the account of a security
holder or holders,  in a registration  statement  covering the sale of shares of
Common Stock to the general public  pursuant to a public  offering in compliance
with the Act (except with respect to any registration  filed on Form S-4 or such
other form which does not include substantially the same information as would be
included in a registration statement covering the sale of shares of Common Stock
to the general public), the Company will: (i) give to Stockholder written notice
thereof  at  least  30 days  before  the  initial  filing  of such  registration
statement;  and (ii) include in such registration (and any related qualification
under blue sky laws) and in any underwriting  involved therein,  all the Shares,
specified  in a written  request,  made  within 30 days  after  receipt  of such
written  notice from the  Company,  by the  Stockholder,  except as set forth in
subparagraphs (b) or below. Notwithstanding the foregoing, the Stockholder shall
not have registration rights with respect to a particular registration statement
in the event that any investor or lender for whom the registration  statement is
filed objects to the  inclusion of other shares of Common  Stock,  including the
Shares, in such registration statement.

                  (b) If the  distribution is to be  underwritten,  the right of
the  Stockholder to  registration  pursuant to this Section shall be conditioned
upon  Stockholder's  participation  in the underwriting and the inclusion of the
Shares  and  securities  underlying  the  Shares,  as the  case  may be,  in the
underwriting to the extent provided herein.  Notwithstanding any other provision
of this Section, if the underwriter  determines that marketing factors require a
limitation of the number of shares to be underwritten, and such determination is
made by such  underwriter in writing,  then the underwriter may limit the number
of the Stockholder's Shares to be included in the registration and underwriting,
or may exclude the Shares from such underwriting.

                  4.   Obligations  of  the  Company.   In  connection   with  a
registration of the Registrable  Securities under Section 3 hereof,  the Company
shall do each of the following:

                  (a)  Prepare and file with the SEC, a  Registration  Statement
with respect to the Registrable Securities,  and thereafter use its best efforts
to cause each Registration  Statement relating to the Registrable  Securities to
become  effective  on or before  120 days from the  filing of such  Registration
Statement  with the SEC, and keep the  Registration  Statement  effective at all
times until the  earliest  (the  "Registration  Period") of (i) the date that is
three years after the Closing Date;  (ii) the date when the Stockholder may sell
all Registrable  Securities  under Rule 144 or (iii) the date the Stockholder no
longer owns any of the  Registrable  Securities,  which  Registration  Statement
shall not contain  any untrue  statement  of a material  fact or omit to state a
material fact required to be stated  therein or necessary to make the statements
therein, in light of the circumstances in which they were made, not misleading;

                                       -3-

<PAGE>



                  (b) Prepare and file with the SEC such  amendments  (including
post-effective amendments) and supplements to the Registration Statement and the
prospectus  used  in  connection  with  the  Registration  Statement  as  may be
necessary to keep the Registration  Statement  effective at all times during the
Registration  Period,  and,  during the  Registration  Period,  comply  with the
provisions  of the  Act  with  respect  to the  disposition  of all  Registrable
Securities of the Company covered by the Registration  Statement until such time
as all of such  Registrable  Securities have been disposed of in accordance with
the  intended  methods of  disposition  by the seller or sellers  thereof as set
forth in the Registration Statement;

                  (c)  The  Company  shall  permit  a  single  firm  of  counsel
designated by the Stockholder to review the Registration  Statement a reasonable
period of time prior to the Company's filing of the Registration  Statement with
the SEC;

                  (d)  Furnish  to  the   Stockholder  (i)  promptly  after  the
Registration Statement is prepared and publicly distributed, filed with the SEC,
or  received  by the  Company,  one  copy of the  Registration  Statement,  each
prospectus,  and each amendment or supplement  thereto,  and (ii) such number of
copies of a prospectus,  and all  amendments  and  supplements  thereto and such
other  documents,  as  the  Stockholder  may  reasonably  request  in  order  to
facilitate  the  disposition  of  the  Registrable   Securities   owned  by  the
Stockholder;

                  (e) As promptly as  practicable  after  becoming aware of such
event,  the Company shall notify the  Stockholder of (i) the issuance by the SEC
of a stop order suspending the effectiveness of the Registration Statement, (ii)
the  happening  of any event of which the Company has  knowledge  as a result of
which the prospectus included in the Registration  Statement, as then in effect,
includes  an untrue  statement  of a material  fact or omits to state a material
fact required to be stated therein or necessary to make the statements  therein,
in light of the  circumstances  under which they were made, not  misleading,  or
(iii) the occurrence or existence of any pending corporate  development that, in
the  reasonable  discretion of the Company,  makes it appropriate to suspend the
availability of the Registration Statement, and use its best efforts promptly to
prepare a supplement or amendment to the Registration  Statement to correct such
untrue  statement  or  omission,  and  deliver  such  number  of  copies of such
supplement  or  amendment  to  the  Stockholder  as he may  reasonably  request;
provided  that, for not more than twenty days (or a total of not more than forty
days in any  twelve  month  period,  the  Company  may delay the  disclosure  of
material non-public information concerning the Company (as well as prospectus or
Registration  Statement updating) the disclosure of which at the time is not, in
the good faith opinion of the Company,  the best interests of the Company and in
the opinion of counsel to the Company (an "Allowed Delay");  provided,  further,
that the Company  shall  promptly (i) notify the  Stockholder  in writing of the
existence of material non-public information giving rise to an Allowed Delay and
(ii) advise the Stockholder in writing to cease all sales under the Registration
Statement  until the end of the Allowed  Delay.  Upon  expiration of the Allowed
Delay,  the Company  shall again be bound by the first  sentence of this Section
4(e) with respect to the information giving rise thereto;

                  (f) As promptly as  practicable  after  becoming aware of such
event,  notify the Stockholder who holds Registrable  Securities being sold (or,
in the event of an underwritten offering,

                                       -4-

<PAGE>



the managing  underwriters)  of the issuance by the SEC of any notice  declaring
the  effectiveness  of the  Registration  Statement  or any stop  order or other
suspension of the  effectiveness of the  Registration  Statement at the earliest
possible time; and

                  (g) Take all other  reasonable  actions  necessary to expedite
and facilitate  disposition by the  Stockholder  of the  Registrable  Securities
pursuant to the Registration Statement.

                  5.  Obligations  of the  Stockholder.  In connection  with the
registration  of the  Registrable  Securities,  the  Stockholder  shall have the
following obligations:

                  (a) It shall be a condition  precedent to the  obligations  of
the Company to complete the registration pursuant to this Agreement with respect
to the  Registrable  Securities of the Stockholder  that the  Stockholder  shall
furnish to the  Company  such  information  regarding  itself,  the  Registrable
Securities held by it, and the intended method of disposition of the Registrable
Securities  held  by  it,  as  shall  be  reasonably   required  to  effect  the
registration of such Registrable  Securities and shall execute such documents in
connection  with such  registration  as the Company may reasonably  request.  At
least five days prior to the first  anticipated  filing date of the Registration
Statement,  the Company  shall notify the  Stockholder  of the  information  the
Company  requires from the  Stockholder  (the  "Requested  Information")  if the
Stockholder  elects  to have  any of the  Stockholder's  Registrable  Securities
included in the  Registration  Statement.  If at least three  Business  Days (as
defined  below)  prior to the  filing  date the  Company  has not  received  the
Requested  Information  from  the  Stockholder,  then the  Company  may file the
Registration   Statement  without  including   Registrable   Securities  of  the
Stockholder;

                  (b)  The   Stockholder   by  acceptance  of  the   Registrable
Securities  agrees to cooperate with the Company as reasonably  requested by the
Company  in  connection  with the  preparation  and  filing of the  Registration
Statement hereunder,  unless the Stockholder has notified the Company in writing
of the Stockholder's  election to exclude all of its Registrable Securities from
the Registration Statement; and

                  (c) The  Stockholder  agrees that,  upon receipt of any notice
from the Company of the happening of any event of the kind  described in Section
4(e) or 4(f), above, the Stockholder will immediately discontinue disposition of
Registrable  Securities  pursuant to the  Registration  Statement  covering such
Registrable  Securities  until the  Stockholder's  receipt  of the copies of the
supplemented or amended prospectus  contemplated by Section 4(e) or 4(f) and, if
so directed by the Company, the Stockholder shall deliver to the Company (at the
expense of the Company) or destroy (and deliver to the Company a certificate  of
destruction)  all  copies in the  Stockholder's  possession,  of the  prospectus
covering  such  Registrable  Securities  current  at the time of receipt of such
notice.

                  6.       Expenses of Registration.

                  (a)  All  reasonable  expenses,  other  than as set  forth  in
Section 6(b) hereof, filings or qualifications pursuant to Section 4, including,
without limitation, all registration, listing, and

                                       -5-

<PAGE>



qualifications fees, printers and accounting fees, the fees and disbursements of
counsel for the Company, shall be borne by the Company.

                  (b) All  underwriting  discounts and  commissions  incurred in
connection with registrations shall be paid by the Stockholder.

                  7. Indemnification.  Hsu shall indemnify and hold harmless the
Company and each officer,  director or control person of any such entity, who is
or may  be a  party  or is or  may be  threatened  to be  made  a  party  to any
threatened,  pending or completed  action,  suit or  proceeding,  whether civil,
criminal,  administrative or investigative, by reason of or arising from (i) any
actual or alleged  misrepresentation  or  misstatement  of facts or  omission to
represent  or  state  facts  made or  alleged  to have  been  made by Hsu to the
Company, (or its officers, directors, employees, agents or representatives),  or
omitted  or  alleged  to have been  omitted  by Hsu,  concerning  Hsu,  or Hsu's
authority to invest or  financial  position in  connection  with the offering or
sale of the Shares, or (ii) any breach of warranty or failure to comply with any
covenant contained in this Agreement,  including,  without limitation,  any such
misrepresentation,  misstatement  or  omission,  or  breach of any  warranty  or
covenant,  contained  herein or any other  document  submitted  by Hsu,  against
losses,  liabilities  and  expenses  for which  the  Company,  or its  officers,
directors  or control  persons  has not  otherwise  been  reimbursed  (including
attorneys'  fees,  judgments,  fines and amounts paid in  settlement  in matters
settled in accordance with the provision of the following paragraph) incurred by
the Company, or such officer, director or control person in connection with such
action, suit or proceeding;  provided,  however,  that Hsu will not be liable in
any such case for losses, claims, damages,  liabilities or expenses that a court
of competent  jurisdiction  shall have found in a final  judgment to have arisen
primarily from the gross negligence or willful  misconduct of the Company or the
party claiming a right to indemnification.

                  In case any  proceeding  shall  be  instituted  involving  any
person  with  respect  to  whom  indemnity  may  be  sought,  such  person  (the
"Indemnified Party") shall promptly notify Hsu, and Hsu, upon the request of the
Indemnified  Party,   shall  retain  counsel  reasonably   satisfactory  to  the
Indemnified  Party to  represent  the  Indemnified  Party and any others Hsu may
designate in such proceedings and shall pay as incurred the fees and expenses of
such counsel related to such proceeding. In any such proceeding, any Indemnified
Party shall have the right to retain its own counsel at its own expense,  except
that Hsu shall pay as incurred the fees and expenses of counsel  retained by the
Indemnified Party in the event that (i) Hsu and the Indemnified Party shall have
mutually  agreed to the  retention of such counsel or, (ii) the named parties to
any such proceeding  (including any impleaded  parties) include both Hsu and the
Indemnified  Party and  representation of both parties by the same counsel would
be  inappropriate,  in the reasonable  opinion of the Indemnified  Party, due to
actual or potential  differing  interests  between them. Hsu shall not be liable
for any settlement of any proceeding  effected without its written consent,  but
if settled with such consent or if there be a final  judgment for the plaintiff,
Hsu agrees to indemnify  the  Indemnified  Party to the extent set forth in this
Agreement.

                  In the event a claim for  indemnification  as described herein
is determined to be  unenforceable  by a final  judgment of a court of competent
jurisdiction, then Hsu shall contribute to

                                       -6-

<PAGE>



the aggregate losses, claims, damages or liabilities to which the Company or its
officers,  directors, agents, employees or controlling persons may be subject in
such amount as is appropriate to reflect the relative  benefits received by each
of the  undersigned  and the party seeking  contribution on the one hand and the
relative faults of Hsu and the party seeking  contribution on the other, as well
as any relevant equitable considerations.

                  The provisions of this Agreement  relating to  indemnification
and  contribution  shall  survive  termination  of this  Agreement  and shall be
binding upon any successors or assigns of Hsu.

                  8.  Termination  of  Registration  Rights.  The rights granted
pursuant  to this  Agreement  shall  terminate  as to the  Stockholder  upon the
occurrence of any of the following:

                  (a) all of the Registrable Securities have been registered; or

                  (b) all of the Registrable Securities may be sold without such
registration pursuant to Rule 144.

                  9.     Miscellaneous.

                  (a) A person or entity is deemed to be a holder of Registrable
Securities  whenever  such  person or entity  owns of  record  such  Registrable
Securities.  If  the  Company  receives  conflicting  instructions,  notices  or
elections  from  two or more  persons  or  entities  with  respect  to the  same
Registrable  Securities,  the Company shall act upon the basis of  instructions,
notice  or  election  received  from the  registered  owner of such  Registrable
Securities.

                  (b) Notices.  All notices,  demands or other communications to
be given or delivered  under or by reason of the  provisions  of this  Agreement
shall be in writing  and shall be deemed to have been  given (a) when  delivered
personally to the recipient, (b) when sent to the recipient by telecopy (receipt
electronically confirmed by sender's telecopy machine) if during normal business
hours of the recipient, otherwise on the next Business Day ("Business Day" means
a day other than Saturday, Sunday or any day on which banks located in the State
of New York are  authorized  or obligated to close),  (c) one Business Day after
the date  when  sent to the  recipient  by  reputable  express  courier  service
(charges  prepaid) or (d) seven  Business Days after the date when mailed to the
recipient by certified or registered mail,  return receipt requested and postage
prepaid. Such notices,  demands and other communications will be sent to Hsu and
to the Company at the addresses indicated below.

                          
                           If to Hsu, to:                             
                                                                      
                           Yungtai Hsu       

           
                           Facsimile No.: 


                                       -7-

<PAGE>



                           With a copy (which shall not constitute notice) to:

                           Lagerlof, Senecal, Bradley, Gosney & Kruse, LLP
                           301 North Lake Avenue, 10th Floor
                           Pasadena, CA  91101
                           Attention:  Timothy J. Gosney
                           Facsimile No.: (626) 793-5900

                           If to the Company, to:

                           Bentley Pharmaceuticals, Inc.
                           Two Urban Centre, Suite 400
                           4890 West Kennedy Blvd.
                           Tampa, Florida 33609
                           Attention:  James R. Murphy
                           Facsimile No.:  (813) 282-8941

                           With a copy (which shall not constitute notice) to:

                           Parker Chapin Flattau & Klimpl, LLP
                           1211 Avenue of the Americas
                           New York, New York 10036
                           Attention: Mark S. Hirsch
                                      Jordan A. Horvath
                           Facsimile No.: (212) 704-6288

                  (c) Assignment; Benefit. This Agreement may not be assigned by
Hsu without the prior written consent of the Company and any assignment  without
such consent shall be void. This Agreement may be assigned by the Company to any
person or entity which purchases all or substantially all of the stock or assets
of the Company or is the  successor  to the Company by merger or  consolidation.
This Agreement  shall be binding upon and inure to the benefit of the respective
successors and permitted assigns of the Company and of Hsu.

                  (d) Severability.  The invalidity or  unenforceability  of any
provisions of this Agreement shall not affect the validity or  enforceability of
any other provision of this Agreement,  each of which shall remain in full force
and effect.

                  (e) Amendments. This Agreement may be amended, supplemented or
modified,  and any  provision  hereof may be waived,  only pursuant to a written
instrument  making  specific  reference to this Agreement  signed by each of the
parties hereto.

                  (f) Counterparts. This Agreement may be executed in any number
of  counterparts,  each of which shall be deemed an  original,  but all of which
together shall constitute one and the same instrument.

                                       -8-

<PAGE>




                  (g)  Governing  Law. This  Agreement  shall be governed by and
construed in accordance  with the laws of the State of New York  applicable to a
contract  executed and  performed  in such State  without  giving  effect to the
conflicts  of laws  principles  thereof,  except that if it is  necessary in any
other  jurisdiction  to have  the law of such  other  jurisdiction  govern  this
Agreement in order for this  Agreement to be effective in any respect,  then the
laws of such other jurisdiction shall govern this Agreement to such extent.

                  (h)      Arbitration of Disputes

                                    (i)  If  any  controversy  or dispute arises
under, out of or in relation to any of the provisions  hereof,  such controversy
or dispute shall be submitted  for  arbitration  in New York,  New York before a
panel of  three  arbitrators,  one of  which  shall  be  selected  by the  party
initiating such  arbitration,  one of which shall be selected by the other party
and the third of which (the  "Third  Arbitrator")  shall be  selected by the two
arbitrators so selected;  provided,  however,  that in the event that such other
arbitrators shall not agree on the selection of the Third Arbitrator,  the Third
Arbitrator shall be selected by the American Arbitration  Association located in
New York,  New York.  Any dispute or  controversy  submitted to  arbitration  in
accordance  with the  provisions  of this Section  shall be  determined  by such
arbitrators in accordance with the Commercial  Arbitration Rules of the American
Arbitration Association then existing.

                                    (ii) The  arbitrators  may award any  relief
which they shall deem proper in the circumstances,  without regard to the relief
which  would  otherwise  be  available  to any party in a court of law or equity
including,  without limitation, an award of money damages, specific performance,
injunctive  relief and/or  declaratory  relief,  however,  such an award may not
include  punitive  damages.  The award and findings of the arbitrators  shall be
conclusive  and  binding  upon all of the  parties  hereto,  whether  or not all
parties hereto participate in the arbitration proceeding,  and judgment upon the
award may be entered in any court of competent jurisdiction upon the application
of  any  party.   The  parties  hereby  agree  that  such  courts  of  competent
jurisdiction  shall  include,  but not be limited to, the courts  located in any
jurisdiction  in which the party  against whom such  judgment is being  enforced
maintains any assets.

                                    (iii)   The   prevailing    party   in   the
arbitration  proceeding  shall be entitled  to recover  from the other party its
reasonable attorneys' fees, costs and expenses incurred in the proceeding and in
any  subsequent  action to enforce or collect upon the decision  rendered in the
arbitration proceeding.

                                    (iv)  Notwithstanding  the  foregoing,   the
parties reserve the right to seek and obtain injunctive  relief,  whether in the
form of a temporary  restraining order,  preliminary  injunction,  injunction to
enforce an arbitration award, or other order of similar import, from the federal
and state  courts  located  in New York,  New York  prior to,  during,  or after
commencement or prosecution or arbitration proceedings of the final decision and
award of the arbitrators;  provided,  however, that such preliminary  injunctive
relief shall be subject to final arbitral decisions.


                                       -9-

<PAGE>


                                    (v)   Each party  hereby consents and agrees
that the federal and state courts  located in New York, New York each shall have
exclusive personal jurisdiction and proper venue with respect to any such action
seeking  injunctive  or similar  relief  hereunder.  In any dispute  between the
parties,  neither party will raise, and each party hereby expressly waives,  any
objection  or  defense to any such court as an  inconvenient  forum.  Each party
hereby waives personal service of any summons, complaint or other process, which
may be delivered by any of the means  permitted  for notices  under Section 9(b)
hereof

                  IN WITNESS  WHEREOF,  the parties have  executed and delivered
this Agreement as of the day and year first written above.

                                         BENTLEY PHARMACEUTICALS, INC.


                                         By:   /s/  James R. Murphy
                                            ------------------------------------
                                            James R. Murphy, Chairman, President
                                             and Chief Executive Officer


                                              /s/ Yungtai Hsu
                                           -------------------------------------
                                           Yungtai Hsu, in his personal capacity


                                      -10-

THE SECURITIES  REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED AND MAY
NOT  BE  TRANSFERRED  UNLESS  (A)  THE  STOCKHOLDER  WISHING  TO  TRANSFER  SUCH
SECURITIES PROVIDES AN OPINION OF COUNSEL REASONABLY CONCURRED IN BY COUNSEL FOR
BENTLEY PHARMACEUTICALS, INC. (THE "COMPANY") STATING THAT THE PROPOSED TRANSFER
OF THE COMPANY'S  SECURITIES  IS EXEMPT FROM OR NOT SUBJECT TO THE  REGISTRATION
PROVISIONS OF ALL APPLICABLE FEDERAL AND STATE LAWS; OR (B) SAID SECURITIES HAVE
BEEN REGISTERED PURSUANT TO THE SECURITIES ACT OF 1933, AS AMENDED.


                                                               February 11, 1999



                          BENTLEY PHARMACEUTICALS, INC.

                     The Transferability of this Warrant is

                       Restricted as Provided in Article 3


                  In partial  consideration  of the  purchase of certain  assets
under an Asset  Purchase  Agreement  dated  February  1,  1999  effective  as of
December  31, 1998  between  Bentley  Pharmaceuticals,  Inc. and Yungtai Hsu and
other  good  and  valuable  consideration,   the  receipt  of  which  is  hereby
acknowledged by BENTLEY PHARMACEUTICALS, INC., Two Urban Centre, Suite 400, 4890
West  Kennedy  Boulevard,  Tampa,  Florida  33609,  a Florida  corporation  (the
"Company"),  YUNGTAI HSU (the "Holder") is hereby granted the right to purchase,
at the initial  exercise price of $ 1.50 per share, at any time until 5:00 P.M.,
New York time,  on December 31,  2008,  Four Hundred  Fifty  Thousand  (450,000)
shares of the Company's common stock, $.02 par value per share (the "Shares").

                  This Warrant  initially is exercisable at a price of $1.50 per
Share  payable  in cash or by  certified  or  official  bank  check  in New York
Clearing  House funds,  subject to  adjustment  as provided in Article 6 hereof.
Upon  surrender  of this  Warrant,  with  the  annexed  Subscription  Form  duly
executed,  together with payment of the Purchase Price (as hereinafter  defined)
for the Shares purchased,  at the offices of the Company,  the registered holder
of this Warrant (the  "Holder")  shall be entitled to receive a  certificate  or
certificates for the Shares so purchased.

                  THIS  WARRANT MAY NOT BE  EXERCISED  AND THE SHARES MAY NOT BE
ISSUED UNTIL A LISTING  APPLICATION  RELATING TO THE SHARES HAS BEEN APPROVED BY
ALL SECURITIES  EXCHANGES ON WHICH THE SHARES OF THE COMPANY'S  COMMON STOCK MAY
THEN BE LISTED AND/OR QUOTED.

<PAGE>



1.       Exercise of Warrant.

                  The   purchase   rights   represented   by  this  Warrant  are
exercisable at the option of the Holder hereof,  in whole or in part (but not as
to fractional Shares  underlying this Warrant),  during any period in which this
Warrant may be exercised as set forth above. In the case of the purchase of less
than all the Shares  purchasable  under this  Warrant,  the Company shall cancel
this  Warrant  upon the  surrender  hereof and shall  execute  and deliver a new
Warrant of like tenor for the balance of the Shares purchasable hereunder.

2.       Issuance of Certificates.

                  Upon  the   exercise  of  this   Warrant,   the   issuance  of
certificates for Shares  underlying this Warrant shall be made forthwith (and in
any event within five business  days  thereafter)  without  charge to the Holder
hereof including, without limitation, any tax which may be payable in respect of
the issuance thereof,  and such certificates shall (subject to the provisions of
Articles 3 hereof) be issued in the name of, or in such names as may be directed
by, the Holder hereof; provided, however, that the Company shall not be required
to pay any tax which may be payable in respect of any  transfer  involved in the
issuance and delivery of any such  certificates in a name other than that of the
Holder  and  the  Company  shall  not be  required  to  issue  or  deliver  such
certificates  unless or until the  person or  persons  requesting  the  issuance
thereof  shall  have paid to the  Company  the  amount of such tax or shall have
established to the  satisfaction of the Company that such tax has been paid. The
certificates  representing the Shares  underlying this Warrant shall be executed
on behalf of the  Company by the  manual or  facsimile  signature  of one of the
present or any future  Chairman or  President  of the Company and any present or
future Vice President or Secretary of the Company.

3.       Restriction on Transfer of Warrant.

                  The  Holder  of  this  Warrant,   by  its  acceptance  hereof,
covenants and agrees that this Warrant is being  acquired as an  investment  and
not with a view to the  distribution  hereof,  and that it may not be exercised,
sold, transferred,  assigned, hypothecated or otherwise disposed of, in whole or
in part  except as  provided  in  Section  13 below or unless in the  opinion of
counsel  concurred in by the  Company's  counsel such  transfer is in compliance
with all applicable securities laws.

4.       Price.

         (a) Initial and Adjusted  Purchase  Price.  The initial  purchase price
shall be $1.50 per Share.  The adjusted  purchase price shall be the price which
shall  result  from time to time  from any and all  adjustments  of the  initial
purchase price in accordance with the provisions of Article 5 hereof.

         (b) Purchase  Price.  The term  "Purchase  Price" herein shall mean the
initial  purchase  price or the  adjusted  purchase  price,  depending  upon the
context.

                                       -2-

<PAGE>



5.       Adjustments of Purchase Price and Number of Shares.

         (a) Subdivision and Combination.  In case the Company shall at any time
subdivide or combine the outstanding  Shares, the Purchase Price shall forthwith
be proportionately decreased in the case of subdivision or increased in the case
of combination.

         (b)  Adjustment  in  Number of  Shares.  Upon  each  adjustment  of the
Purchase  Price  pursuant  to the  provisions  of this  Article 5, the number of
Shares  issuable  upon the  exercise  of this  Warrant  shall be adjusted to the
nearest full Share by multiplying a number equal to the Purchase Price in effect
immediately  prior to such  adjustment  by the  number of Shares  issuable  upon
exercise of this Warrant  immediately  prior to such adjustment and dividing the
product so obtained by the adjusted Purchase Price.

         (c)  Reclassification,  Consolidation,  Merger,  etc.  In  case  of any
reclassification or change of the outstanding Shares (other than a change in par
value to no par value,  or from no par value to par  value,  or as a result of a
subdivision or combination),  or in the case of any consolidation of the Company
with,  or  merger  of  the  Company  into,  another  corporation  (other  than a
consolidation  or merger in which the Company is the surviving  corporation  and
which  does not  result in any  reclassification  or  change of the  outstanding
Shares,  except a change as a result of a  subdivision  or  combination  of such
shares  or a change in par  value,  as  aforesaid),  or in the case of a sale or
conveyance to another corporation of the property of the Company as an entirety,
the Holder of this Warrant shall  thereafter have the right to purchase upon the
exercise  of this  Warrant  the kind and  number  of  shares  of stock and other
securities  and  property   receivable  upon  such   reclassification,   change,
consolidation, merger, sale or conveyance as if the Holder were the owner of the
Shares  underlying  this  Warrant  immediately  prior to any such  events at the
Purchase  Price  in  effect  immediately  prior  to the  record  date  for  such
reclassification,  change, consolidation,  merger, sale or conveyance as if such
Holder had exercised this Warrant.

6.       Exchange and Replacement of Warrant.

                  This  Warrant  is  exchangeable  without  expense,   upon  the
surrender hereof by the registered  Holder at the principal  executive office of
the  Company  for a new  Warrant  of like  tenor  and date  representing  in the
aggregate  the right to purchase  the same  number of Shares as are  purchasable
hereunder in such  denominations  as shall be designated by the Holder hereof at
the time of such surrender.

                  Upon   receipt   by  the   Company  of   evidence   reasonably
satisfactory  to it of the  loss,  theft,  destruction  or  mutilation  of  this
Warrant,  and, in case of loss,  theft or destruction,  of indemnity or security
reasonably  satisfactory  to  it,  and  reimbursement  to  the  Company  of  all
reasonable expenses  incidental thereto,  and upon surrender and cancellation of
this Warrant,  if mutilated,  the Company will make and deliver a new Warrant of
like tenor, in lieu of this Warrant.

                                       -3-

<PAGE>



7.       Elimination of Fractional Interests.

                  The  Company  shall  not be  required  to  issue  certificates
representing  fractions of Shares on the exercise of this Warrant,  nor shall it
be required to issue scrip or pay cash in lieu of fractional interests, it being
the intent of the parties  that all  fractional  interests  shall be  eliminated
pursuant to Section 5(b).

8.       Reservation and Listing of Securities.

                  The Company shall at all times reserve and keep  available out
of its authorized  Shares,  solely for the purpose of issuance upon the exercise
of this  Warrant,  such number of Shares as shall be issuable  upon the exercise
hereof and thereof. The Company covenants and agrees that, upon exercise of this
Warrant and payment of the Purchase  Price  therefor,  all Shares  issuable upon
such exercise shall be duly and validly issued,  fully paid and  non-assessable.
As long as  this  Warrant  shall  be  outstanding,  the  Company  shall  use its
reasonable  best efforts to cause all Shares  issuable upon the exercise of this
Warrant to be listed  (subject to official notice of issuance) on all securities
exchanges on which the Shares of the  Company's  Common Stock may then be listed
and/or quoted.

9.       Repurchase at Option of Holder.

         (a) If on December 31, 2000 (the "Repurchase  Date"),  the Market Price
(as defined  herein) does not equal or exceed 150 % of the Purchase  Price,  the
Holder shall have the right (the "Put Right") to require the Company to purchase
all or a portion of this  Warrant  relating to that  number of Shares  which the
Holder is relinquishing its right to purchase (the "Relinquished Shares"), for a
price equal to $0.50  (fifty  cents)  multiplied  by the number of  Relinquished
Shares.  The Put Right must be exercised by a written  notice from the Holder to
the Company  within ten (10) days of the  Repurchase  Date and the Company shall
pay to the Holder the amounts owing hereunder within ten (10) days of receipt of
such  notice,  this  Warrant  and such other  documentation  as the  Company may
reasonably require.

         (b) The Put Right shall not be exercisable by the Holder if, during any
twenty  consecutive  trading  days  between the issuance of this Warrant and the
Repurchase  Date,  the Market  Price shall be equal to or greater than $3.00 per
share.

         (c) The "Market  Price" per share on any date shall be deemed to be the
daily closing price per share. The closing price per Share for each day shall be
the last  reported  sales price regular way or, in case no such sale takes place
on such day,  the average of the closing bid and asked  prices  regular  way, in
either  case on the  American  Stock  Exchange,  or, if the Common  Stock is not
listed or admitted to trading on the American Stock  Exchange,  on the principal
national  securities exchange on which the Common Stock is listed or admitted to
trading,  or if it is  not  listed  or  admitted  to  trading  on  any  national
securities exchange or no such quotations are available,  the last reported sale
price, or if not so reported, the average of the closing bid and asked prices as
furnished by any New York Stock Exchange  member firm selected from time to time
by the Company for that purpose, or,

                                       -4-

<PAGE>



if no such quotations are available, the fair market value as determined in good
faith in the  exercise  of their  reasonable  business  judgment by the Board of
Directors of the Company.

10.      Repurchase at Option of the Company

                  This  Warrant  may be redeemed at the option of the Company at
any time,  at a  redemption  price of $0.05 per Share for which the  Warrant  is
exercisable,  provided  the Market  Price for the  Shares  for any  twenty  (20)
consecutive trading days after the issuance of this Warrant shall be equal to or
greater than $5.00 per share.  Notice of redemption shall be given in writing to
the Holder not less than ten days before the date fixed for  redemption.  On and
after the date  fixed for  redemption,  the  Holder  shall  have no rights  with
respect to this Warrant  except to receive the $0.05 per Share upon surrender of
the Warrant.

11.      Notices.

                  All notices,  demands or other  communications  to be given or
delivered  under or by  reason of the  provisions  of this  Warrant  shall be in
writing and shall be deemed to have been given (a) when delivered  personally to
the   recipient,   (b)  when  sent  to  the   recipient  by  telecopy   (receipt
electronically confirmed by sender's telecopy machine) if during normal business
hours of the recipient, otherwise on the next Business Day, (c) one Business Day
after the date when sent to the recipient by reputable  express  courier service
(charges  prepaid) or (d) seven  Business Days after the date when mailed to the
recipient by certified or registered mail,  return receipt requested and postage
prepaid. Such notices, demands and other communications will be sent:

                  (a)  if  to  the  registered  Holder  of  this Warrant, to the
         address of such Holder as shown on the books of the Company; or

                  (b) if to the  Company,  to the address set forth on the first
         page of this  Warrant  or to such  other  address  as the  Company  may
         designate by notice to the Holder.

12.      Amendments.

                  The terms,  provisions  and conditions of this Warrant may not
be changed, modified or amended in any manner except by an instrument in writing
duly executed by both parties hereto.

13.      Binding Effect; Assignment.

                  (a) This Warrant is not assignable or transferable without the
written consent of the Company, except by operation of law or as provided in (b)
below.

                  (b) This  Warrant  shall not be  transferable  by Holder other
than  to a  "Permitted  Transferee"  (as  defined  below);  provided,  that  any
Permitted Transferee shall be absolutely prohibited from transferring all or any
portion of this Warrant other than to Holder or another

                                       -5-

<PAGE>



Permitted  Transferee of Holder;  and provided  further,  that if Holder dies or
becomes  incapacitated,  this Warrant may be exercised by Holder's estate, legal
representative  or  beneficiary,  as the case may be, subject to all other terms
and conditions contained in this Warrant.

                  (c) For purposes of this Warrant,  Permitted Transferees shall
include  only the members of the  Holder's  "immediate  family"  (which shall be
limited to  Holder's  spouse,  children,  and  parents),  and to trusts for such
person's  own benefit  and/or for the  benefit of members of Holder's  immediate
family;  provided,  that such Permitted  Transferees must agree in writing to be
bound  by all of the  terms  of  this  Warrant  to the  same  extent  as  Holder
hereunder,  in form  acceptable  to counsel to the  Company,  including  but not
limited to  restrictions on the exercise of this Warrant and on transfers of the
Shares,  as the case may be, following  exercise of this Warrant,  such that any
Shares so acquired shall be held subject to the terms of this Warrant.

14.      Governing Law.

                  This  Warrant  shall  be  governed  by,  and  interpreted  and
enforced in accordance with, the laws of the State of New York without regard to
principles of choice of law or conflict of laws.

15.      Arbitration of Disputes

                  (a) If any  controversy or dispute arises under,  out of or in
relation to any of the provisions  hereof,  such controversy or dispute shall be
submitted  for  arbitration  in New  York,  New  York  before  a panel  of three
arbitrators,  one of which  shall  be  selected  by the  party  initiating  such
arbitration,  one of which shall be selected by the other party and the third of
which (the  "Third  Arbitrator")  shall be selected  by the two  arbitrators  so
selected; provided, however, that in the event that such other arbitrators shall
not agree on the selection of the Third  Arbitrator,  the Third Arbitrator shall
be selected by the American  Arbitration  Association  located in New York,  New
York. Any dispute or controversy submitted to arbitration in accordance with the
provisions  of this Section 12.10 shall be  determined  by such  arbitrators  in
accordance  with the Commercial  Arbitration  Rules of the American  Arbitration
Association then existing.

                  (b) The arbitrators may award any relief which they shall deem
proper in the circumstances,  without regard to the relief which would otherwise
be  available  to any  party  in a court  of law or  equity  including,  without
limitation, an award of money damages,  specific performance,  injunctive relief
and/or  declaratory  relief,  however,  such an award may not  include  punitive
damages.  The award and  findings of the  arbitrators  shall be  conclusive  and
binding  upon all of the  parties  hereto,  whether  or not all  parties  hereto
participate in the  arbitration  proceeding,  and judgment upon the award may be
entered  in any court of  competent  jurisdiction  upon the  application  of any
party. The parties hereby agree that such courts of competent jurisdiction shall
include,  but not be limited to, the courts located in any jurisdiction in which
the party against whom such judgment is being enforced maintains any assets.

                                       -6-

<PAGE>



                  (c) The prevailing  party in the arbitration  proceeding shall
be entitled  to recover  from the other party its  reasonable  attorneys'  fees,
costs and expenses  incurred in the proceeding  and in any subsequent  action to
enforce or collect upon the decision rendered in the arbitration proceeding.

                  (d)  Notwithstanding  the foregoing,  the parties  reserve the
right to seek and obtain injunctive  relief,  whether in the form of a temporary
restraining order, preliminary injunction,  injunction to enforce an arbitration
award,  or other order of similar  import,  from the  federal  and state  courts
located  in New  York,  New York  prior to,  during,  or after  commencement  or
prosecution  or  arbitration  proceedings of the final decision and award of the
arbitrators; provided, however, that such preliminary injunctive relief shall be
subject to final arbitral decisions.

                  (e) Each party hereby consents and agrees that the federal and
state courts located in New York,  New York each shall have  exclusive  personal
jurisdiction and proper venue with respect to any such action seeking injunctive
or similar relief hereunder.  In any dispute between the parties,  neither party
will raise, and each party hereby expressly waives,  any objection or defense to
any such court as an  inconvenient  forum.  Each party  hereby  waives  personal
service of any summons,  complaint or other  process,  which may be delivered by
any of the means permitted for notices under Section 11 hereof.

16.      Descriptive Headings.

                  The  descriptive  headings  of the  several  sections  of this
Warrant are  inserted for  convenience  only and shall not control or affect the
meaning or construction of any of the provisions hereof.


                  WITNESS the seal of the Company and the  signature of its duly
authorized officers.


                                      BENTLEY PHARMACEUTICALS, INC.
[SEAL]


                                      By:   /s/ James R. Murphy  
                                            ------------------------------------
                                                James R. Murphy
                                         Chairman and Chief Executive Officer

Attest:


/s/ Michael D. Price
- ---------------------------
Michael D. Price, Secretary


                                       -7-

<PAGE>


                                SUBSCRIPTION FORM

                    (To be Executed by the Registered Holder

                        in order to Exercise the Warrant)


                  The  undersigned  hereby  irrevocably  elects to exercise  the
right to purchase  _____  Shares by this  Warrant  according  to the  conditions
hereof and herewith makes payment of the Purchase Price of such Shares in full.



                                                ________________________________
                                                Signature



                                                ________________________________
                                                Address



Dated: ___________, _____.                      ________________________________
                                                Social Security Number or
                                                Taxpayer's Identification Number


                                       -8-

                             SUBSCRIPTION AGREEMENT
                             ----------------------

                          BENTLEY PHARMACEUTICALS, INC.
                          -----------------------------

Bentley Pharmaceuticals, Inc.
Two Urban Centre, Suite 400
4890 West Kennedy Blvd.
Tampa, Florida 33609

                                                               February 11, 1999

Dear Sir or Madam:

                  Upon the  terms  and  subject  to the  conditions  of an Asset
Purchase  Agreement,  dated  February 1, 1999  effective as of December 31, 1998
(the "Asset  Purchase  Agreement"),  between Conrex  Pharmaceutical  Corporation
("Conrex ") and Yungtai Hsu ("Hsu"),  in which Conrex  agreed to sell certain of
its assets to Hsu,  Conrex has agreed to accept 359,282 shares (the "Shares") of
common  stock,  $0.02 par  value  per share  (the  "Common  Stock")  of  Bentley
Pharmaceuticals,  Inc. (the "Company") as part of the Purchase Price (as defined
in the Asset Purchase  Agreement).  Therefore,  in consideration of the premises
and  the  mutual  covenants   contained  herein  and  other  good  and  valuable
consideration,  the receipt and  sufficiency  of which are hereby  acknowledged,
Conrex hereby agrees to:

                  1.  Subscription.  Conrex hereby  applies to subscribe for the
Shares. Once this Subscription  Agreement (this "Agreement") is executed by both
Conrex and the  Company,  it is intended to create a binding  agreement  between
Conrex and the Company with respect to the terms and conditions described below.

                  2.   Representations   and   Warranties   of  Conrex.   Conrex
acknowledges, represents, warrants and agrees as follows:

                                    (a) Organization and  Authorization.  Conrex
is a corporation duly organized, validly existing and in good standing under the
laws of the state of New Jersey and is  qualified  to do  business  as a foreign
corporation in the State of Pennsylvania  and has all requisite  corporate power
and  authority  to  purchase  and  hold the  Shares.  Conrex  has all  requisite
corporate  power and  authority  to enter into this  Agreement,  to purchase the
Shares hereunder and to carry out and perform its obligations under the terms of
this Agreement and the consummation by Conrex of the  transactions  contemplated
hereby  requires no other  proceedings  on the part of Conrex.  The  undersigned
signatory  has all right,  power and  authority  to  execute  and  deliver  this
Agreement  on behalf of  Conrex.  This  Agreement  has been  duly  executed  and
delivered by Conrex and,  assuming the execution and delivery hereof and thereof
by the Company,  will  constitute  the legal,  valid and binding  obligations of
Conrex, enforceable against Conrex in accordance with its terms, except as the

<PAGE>



same  may be  limited  by  applicable  bankruptcy,  insolvency,  reorganization,
moratorium or other similar laws affecting the rights of creditors generally and
the availability of equitable remedies.

                                    (b) Due  Diligence.  Conrex  has  received a
copy  of  such  documents  as  requested  by it,  has  carefully  reviewed  such
documents,  has  had  the  opportunity  to  obtain  any  additional  information
necessary to verify the accuracy of the information  contained in such documents
and has been given the opportunity to meet with  representatives  of the Company
and to have them answer any  questions  and provide any  additional  information
regarding the terms and conditions of this particular investment deemed relevant
by Conrex,  and all such questions have been answered and requested  information
provided  to  Conrex's  full  satisfaction.  Among the  documents  received  and
reviewed by Conrex are:  (i) the  Company's  Annual  Report on Form 10-K for the
year ended December 31, 1997; (ii) the Company's  Quarterly Reports on Form 10-Q
for the quarters  ended March 31,  1998,  June 30, 1998 and  September  30, 1998
(such documents are collectively  referred to in this Agreement as the "Exchange
Act Reports");  (iii) the Registration  Statement and (iv) a Registration Rights
Agreement between the Company and Conrex with respect to the Shares, dated as of
the date hereof (the "Registration Rights Agreement.") In making its decision to
accept the Shares as part of the Purchase  Price,  Conrex has relied solely upon
its review of the documents referred to above and this Agreement and independent
investigations made by it or its representatives.

                                    (c) No Legal Advice from the Company. Conrex
acknowledges  that it has had the  opportunity  to review this Agreement and the
transactions  contemplated  by this Agreement with its own legal counsel and tax
advisors.  Except for any statements or  representations  of the Company made in
this  Agreement,  in the  Exchange  Act Reports and in the  Registration  Rights
Agreement,  Conrex is relying solely on such counsel and advisors and not on any
statements or  representations  of the Company or any of its  representative  or
agents for legal, tax or investment advice with respect to this investment,  the
transactions  contemplated  by  this  Agreement  or the  securities  laws of any
jurisdiction.

                                    (d)  Not  an  Affiliate.  Conrex  is  not an
officer,  director  or  "affiliate"  (as that term is defined in Rule 405 of the
Act) of the Company.

                                    (e)   Reliance   on   Representations    and
Warranties.  Conrex understands that the Shares are being offered and sold to it
in reliance on specific provisions of United States federal and state securities
laws and  that the  Company  is  relying  upon the  truth  and  accuracy  of the
representations,  warranties, agreements,  acknowledgments and understandings of
Conrex set forth in this  Agreement in order to determine the  applicability  of
such provisions.

                                    (f) No Registration. Conrex understands that
the sale of the Shares has not been  registered  under the Act, in reliance upon
an exemption  therefrom by virtue of Section 4(2) and  Regulation D  promulgated
under the Act. Conrex  understands that the Shares must be held indefinitely and
may not be offered,  transferred,  resold,  pledged,  hypothecated  or otherwise
disposed of until the sale or other  transfer  thereof is  registered  under the
Act,  pursuant to the terms and conditions of the Registration  Rights Agreement
or unless an exemption from such registration

                                       -2-

<PAGE>



is available at that time.  Conrex is aware that it will be required to bear the
financial  risks of this  investment  for an  indefinite  period of time  unless
transferred  in accordance  with the above.  Conrex  covenants  that it will not
knowingly  make any sale,  transfer  or other  disposition  of the Shares or any
interest  therein in violation of the Act, the Exchange Act of 1934, as amended,
or the rules and regulations promulgated under either of said Acts.

                                    (g) Investment  Intent.  Conrex is acquiring
the Shares  solely for its own account as  principal  and not with a view to the
distribution  thereof to or for the benefit or account of any other  person,  in
whole or in part,  and no other  person  has a  direct  or  indirect  beneficial
interest in such  Shares.  Conrex  understands  and agrees that it must bear the
economic risk of its investment in the Shares for an indefinite  period of time.
Conrex will not take any short  position in the Shares and not otherwise  engage
in any hedging transactions such as option writing,  equity swaps or other types
of derivative transactions with respect to the Shares.

                                    (h) Additional Transfer Restrictions. Conrex
understands and agrees that, in addition to the  restrictions  set forth in this
Agreement,  the following  restrictions  and  limitations  are applicable to its
purchase  and any resales,  pledges,  hypothecations  or other  transfers of the
Shares:

                                        (i) The following legend  reflecting all
applicable   restrictions  will  be  placed  on  any   certificate(s)  or  other
document(s)  evidencing  the Shares and Conrex  must  comply  with the terms and
conditions   set  forth  in  such  legends   prior  to  any  resales,   pledges,
hypothecations or other transfers of the Shares:

                                        "THE  SECURITIES   REPRESENTED  BY  THIS
                                        CERTIFICATE  HAVE  NOT  BEEN  REGISTERED
                                        UNDER  THE  SECURITIES  ACT OF 1933,  AS
                                        AMENDED (THE "ACT") OR APPLICABLE  STATE
                                        SECURITIES  LAWS.  THE  SECURITIES  HAVE
                                        BEEN  ACQUIRED FOR  INVESTMENT  PURPOSES
                                        ONLY AND MAY NOT BE  OFFERED  FOR  SALE,
                                        SOLD, HYPOTHECATED, ASSIGNED, PLEDGED OR
                                        OTHERWISE  TRANSFERRED IN THE ABSENCE OF
                                        AN  EFFECTIVE   REGISTRATION   STATEMENT
                                        COVERING THE SECURITIES UNDER THE ACT OR
                                        APPLICABLE  STATE SECURITIES LAWS, OR AN
                                        OPINION OF COUNSEL  SATISFACTORY  TO THE
                                        ISSUER THAT REGISTRATION IS NOT REQUIRED
                                        UNDER  THE  ACT  OR   APPLICABLE   STATE
                                        SECURITIES LAWS."

                                       -3-

<PAGE>



                                        (ii)  Stop  transfer  instructions  have
been or will be placed on any  certificates  or other  documents  evidencing the
Shares so as to restrict the resale,  pledge,  hypothecation  or other  transfer
thereof in accordance with the provisions hereof.

                                    (i)   Termination   of   Restrictions.   The
restrictions upon the transferability of the Shares shall cease and terminate as
to any  particular  Shares (i) when, in the opinion of Parker  Chapin  Flattau &
Klimpl,  LLP  or  other  counsel  reasonably  acceptable  to the  Company,  such
restrictions  are no longer required in order to assure  compliance with the Act
or (ii) when,  in the opinion of Parker  Chapin  Flattau & Klimpl,  LLP or other
counsel  reasonably  acceptable  to the  Company,  such  Shares  shall have been
registered under the Act or transferred in reliance upon the exemption  afforded
by Section 4(1) of the Act by virtue of Rule 144.

                                    (j) Indemnification.  Conrex shall indemnify
and hold  harmless the Company and each officer,  director or control  person of
any such entity,  who is or may be a party or is or may be threatened to be made
a party to any  threatened,  pending or completed  action,  suit or  proceeding,
whether  civil,  criminal,  administrative  or  investigative,  by  reason of or
arising  from (i) any actual or alleged  misrepresentation  or  misstatement  of
facts or omission to  represent or state facts made or alleged to have been made
by Conrex to the  Company,  (or its  agents or  representatives),  or omitted or
alleged to have been omitted by Conrex, concerning Conrex, or Conrex's authority
to invest or financial  position in connection  with the offering or sale of the
Shares,  or (ii) any breach of warranty  or failure to comply with any  covenant
contained  in  this  Agreement,   including,   without   limitation,   any  such
misrepresentation,  misstatement  or  omission,  or  breach of any  warranty  or
covenant,  contained herein or any other document  submitted by Conrex,  against
losses,  liabilities  and  expenses  for which  the  Company,  or its  officers,
directors  or control  persons  has not  otherwise  been  reimbursed  (including
attorneys'  fees,  judgments,  fines and amounts paid in  settlement  in matters
settled in accordance with the provision of the following paragraph) incurred by
the Company, or such officer, director or control person in connection with such
action, suit or proceeding; provided, however, that Conrex will not be liable in
any such case for losses, claims, damages,  liabilities or expenses that a court
of competent  jurisdiction  shall have found in a final  judgment to have arisen
primarily from the gross negligence or willful  misconduct of the Company or the
party claiming a right to indemnification.

                  In case any  proceeding  shall  be  instituted  involving  any
person  with  respect  to  whom  indemnity  may  be  sought,  such  person  (the
"Indemnified  Party") shall promptly notify Conrex, and Conrex, upon the request
of the Indemnified Party,  shall retain counsel  reasonably  satisfactory to the
Indemnified  Party to represent the Indemnified  Party and any others Conrex may
designate in such proceedings and shall pay as incurred the fees and expenses of
such counsel related to such proceeding. In any such proceeding, any Indemnified
Party shall have the right to retain its own counsel at its own expense,  except
that Conrex shall pay as incurred  the fees and expenses of counsel  retained by
the  Indemnified  Party in the event that (i) Conrex and the  Indemnified  Party
shall have  mutually  agreed to the retention of such counsel or, (ii) the named
parties to any such proceeding  (including any impleaded  parties)  include both
Conrex and the Indemnified Party and  representation of both parties by the same
counsel would be inappropriate, in the reasonable opinion

                                       -4-

<PAGE>



of the Indemnified Party, due to actual or potential differing interests between
them.  Conrex shall not be liable for any settlement of any proceeding  effected
without its written  consent,  but if settled with such consent or if there be a
final  judgment for the  plaintiff,  Conrex agrees to indemnify the  Indemnified
Party to the extent set forth in this Agreement.

                  In the event a claim for  indemnification  as described herein
is determined to be  unenforceable  by a final  judgment of a court of competent
jurisdiction,  then Conrex shall  contribute  to the aggregate  losses,  claims,
damages or liabilities to which the Company or its officers,  directors, agents,
employees or controlling persons may be subject in such amount as is appropriate
to reflect the relative  benefits  received by each of the  undersigned  and the
party seeking contribution on the one hand and the relative faults of Conrex and
the party seeking  contribution on the other, as well as any relevant  equitable
considerations.

                  The provisions of this Agreement  relating to  indemnification
and  contribution  shall  survive  termination  of this  Agreement  and shall be
binding upon any successors or assigns of Conrex.

                                    (k) Opportunity to Ask Questions. Conrex has
had a reasonable  opportunity  to ask questions of and receive  answers from the
Company  concerning  the  Company  and  the  transactions  contemplated  by this
Agreement,  and all such  questions,  if any,  have  been  answered  to the full
satisfaction of Conrex.

                  3.  Representations and Warranties of the Company. The Company
acknowledges, represents, warrants and agrees as follows:

                                    (a)  Organization  and  Authorization.   The
Company is a corporation  duly organized,  validly existing and in good standing
under the laws of the state of Florida  and has all req uisite  corporate  power
and authority to own and operate its  properties  and assets and to carry on its
business as currently  conducted.  The Company is not in default or violation of
any material  term or provision of its Articles of  Incorporation  or Bylaws nor
will the consummation of the  transactions  contemplated by this Agreement cause
any such default or violation. The Company has all requisite corporate power and
authority  to enter into this  Agreement,  to sell the Shares  hereunder  and to
carry out and perform its obligations  under the terms of this Agreement subject
to the above.  This Agreement is a valid and binding  obligation of the Company,
enforceable in accordance with its terms.

                                    (b)  Capitalization.  The authorized capital
stock of the Company consists of 35,000,000 shares of Common Stock and 2,000,000
shares of Preferred Stock, par value $.02 per share. Upon issuance of the Shares
pursuant to the terms of this  Agreement  and payment  therefor  pursuant to the
terms of an Asset  Purchase  Agreement  between Hsu and the Company,  the Shares
will be duly  authorized,  validly issued,  fully paid and  nonassessable.  Upon
issuance, the Shares will not be subject to any preemptive or other preferential
rights or similar statutory or contractual rights.

                                       -5-

<PAGE>



                  The Closing shall take place as soon as practicable  after (i)
due  execution  by Conrex and  acceptance  by the  Company of this  Subscription
Agreement and (ii) the closings as contemplated by the Asset Purchase  Agreement
and the Asset Purchase Agreement between Hsu and the Company.

                  4. Indemnity by the Company.  The Company shall  indemnify and
hold harmless Conrex and each officer, director or control person of Conrex from
any claims or demands,  including without limitation  reasonable  attorneys fees
and expenses, relating to any liability to ETR and Associates,  Robert S. Cohen,
Creative Technologies, Inc., a Delaware corporation with offices in Jersey City,
New Jersey, and/or each of their respective affiliates,  for commissions related
to the  transactions  arising  under this  Agreement  and/or the Asset  Purchase
Agreement.

                  5.       Miscellaneous.

                                    (a) Notices.  All notices,  demands or other
communications  to be given or delivered under or by reason of the provisions of
this  Agreement  shall be in writing  and shall be deemed to have been given (a)
when delivered  personally to the  recipient,  (b) when sent to the recipient by
telecopy  (receipt  electronically  confirmed by sender's  telecopy  machine) if
during normal  business hours of the  recipient,  otherwise on the next Business
Day ("Business Day" means a day other than Saturday,  Sunday or any day on which
banks  located in the State of New York are  authorized  or obligated to close),
(c) one  Business  Day after the date when sent to the  recipient  by  reputable
express courier service  (charges  prepaid) or (d) seven Business Days after the
date when mailed to the  recipient  by  certified  or  registered  mail,  return
receipt  requested  and  postage  prepaid.  Such  notices,   demands  and  other
communications  will be sent  to  Conrex  and to the  Company  at the  addresses
indicated below.

                           If to Conrex, to:

                           Conrex Pharmaceutical Corporation
                           5217 West Chester Pike
                           Newtown Square, Pennsylvania 19073
                           Attention:  Phyllis Hsieh
                           Facsimile No.: (610) 355-2453


                                       -6-

<PAGE>



                           with a copy to:

                           Synnestvedt & Lechner LLP
                           Suite 2600 Aramark Tower
                           1101 Market Street
                           Philadelphia, PA 19107
                           Attention: John T. Synnestvedt
                           Facsimile No.: (215) 923-2189

                           If to the Company, to:

                           Bentley Pharmaceuticals, Inc.
                           Two Urban Centre, Suite 400
                           4890 West Kennedy Blvd.
                           Tampa, Florida 33609
                           Attention:  James R. Murphy
                           Facsimile:  (813) 282-8941

                           With a copy to:

                           Parker Chapin Flattau & Klimpl, LLP
                           1211 Avenue of the Americas
                           New York, New York 10036
                           Attention: Mark S. Hirsch
                                      Jordan A. Horvath
                           Facsimile: (212) 704-6288


                                    (b) Assignment;  Benefit. This Agreement may
not be assigned by Conrex  without the prior written  consent of the Company and
any  assignment  without  such  consent  shall be void.  This  Agreement  may be
assigned  by  the  Company  to any  person  or  entity  which  purchases  all or
substantially  all of the stock or assets of the Company or is the  successor to
the Company by merger or consolidation. This Agreement shall be binding upon and
inure to the benefit of the respective  successors and permitted  assigns of the
Company and of Conrex.

                                    (c)   Severability.    The   invalidity   or
unenforceability  of any  provisions  of this  Agreement  shall not  affect  the
validity or  enforceability  of any other provision of this  Agreement,  each of
which shall remain in full force and effect.

                                    (d)   Amendments.   This  Agreement  may  be
amended,  supplemented or modified, and any provision hereof may be waived, only
pursuant to a written  instrument  making  specific  reference to this Agreement
signed by each of the parties hereto.

                                       -7-

<PAGE>



                                    (e)  Counterparts.  This  Agreement  may  be
executed  in any  number  of  counterparts,  each of which  shall be  deemed  an
original,  but  all  of  which  together  shall  constitute  one  and  the  same
instrument.

                                    (f) Governing Law. This  Agreement  shall be
governed by and construed in  accordance  with the laws of the State of New York
applicable to a contract  executed and  performed in such State  without  giving
effect  to the  conflicts  of  laws  principles  thereof,  except  that if it is
necessary in any other  jurisdiction to have the law of such other  jurisdiction
govern  this  Agreement  in order  for this  Agreement  to be  effective  in any
respect, then the laws of such other jurisdiction shall govern this Agreement to
such extent.

                                    (g) Arbitration of Disputes

                                        (i) If any controversy or dispute arises
under, out of or in relation to any of the provisions  hereof,  such controversy
or dispute shall be submitted  for  arbitration  in New York,  New York before a
panel of  three  arbitrators,  one of  which  shall  be  selected  by the  party
initiating such  arbitration,  one of which shall be selected by the other party
and the third of which (the  "Third  Arbitrator")  shall be  selected by the two
arbitrators so selected;  provided,  however,  that in the event that such other
arbitrators shall not agree on the selection of the Third Arbitrator,  the Third
Arbitrator shall be selected by the American Arbitration  Association located in
New York,  New York.  Any dispute or  controversy  submitted to  arbitration  in
accordance  with the  provisions  of this Section  shall be  determined  by such
arbitrators in accordance with the Commercial  Arbitration Rules of the American
Arbitration Association then existing.

                                        (ii)  The   arbitrators  may  award  any
relief which they shall deem proper in the circumstances,  without regard to the
relief  which would  otherwise  be  available  to any party in a court of law or
equity  including,  without  limitation,  an award of  money  damages,  specific
performance, injunctive relief and/or declaratory relief, however, such an award
may not include  punitive  damages.  The award and  findings of the  arbitrators
shall be conclusive and binding upon all of the parties  hereto,  whether or not
all parties hereto participate in the arbitration proceeding,  and judgment upon
the  award  may be  entered  in any  court of  competent  jurisdiction  upon the
application of any party. The parties hereby agree that such courts of competent
jurisdiction  shall  include,  but not be limited to, the courts  located in any
jurisdiction  in which the party  against whom such  judgment is being  enforced
maintains any assets.

                                        (iii) The costs of the  arbitration  and
each   party's   associated   costs   shall  be  borne  by  the  losing   party.
Notwithstanding the foregoing,  if the parties reach a compromise,  the costs of
the arbitration  shall be borne equally by the parties and each party shall bear
its own associated costs.

                                        (iv) Notwithstanding the foregoing,  the
parties reserve the right to seek and obtain injunctive  relief,  whether in the
form of a temporary  restraining order,  preliminary  injunction,  injunction to
enforce an arbitration award, or other order of similar import,

                                       -8-

<PAGE>


from the  federal  and state  courts  located  in New York,  New York  prior to,
during, or after  commencement or prosecution or arbitration  proceedings of the
final  decision  and  award of the  arbitrators;  provided,  however,  that such
preliminary injunctive relief shall be subject to final arbitral decisions.

                                        (v)  Each  party  hereby   consents  and
agrees  that the  federal and state  courts  located in New York,  New York each
shall have exclusive personal  jurisdiction and proper venue with respect to any
such action  seeking  injunctive  or similar  relief  hereunder.  In any dispute
between the parties,  neither party will raise,  and each party hereby expressly
waives,  any  objection or defense to any such court as an  inconvenient  forum.
Each party hereby  waives  personal  service of any summons,  complaint or other
process,  which may be delivered by any of the means permitted for notices under
Section 5(a) hereof.

                                    (h)   Entire   Agreement.   This   Agreement
constitutes the entire agreement  between Conrex and the Company with respect to
the subject matter hereof.

                                       CONREX  PHARMACEUTICAL CORPORATION


                                       By: /s/ Phyllis Hsieh
                                           ------------------------------  
                                           Phyllis Hsieh, President


ACCEPTED AND AGREED:

BENTLEY PHARMACEUTICALS, INC.

By:  /s/ James R. Murphy
     ------------------------------------                                
     James R. Murphy, Chairman, President
     and Chief Executive Officer



                                       -9-

                          REGISTRATION RIGHTS AGREEMENT
                          -----------------------------


                  THIS REGISTRATION  RIGHTS AGREEMENT,  is made and entered into
as of  February  11,  1999  between  BENTLEY  PHARMACEUTICALS,  INC.,  a Florida
corporation (the "Company") and CONREX PHARMACEUTICAL  CORPORATION, a New Jersey
corporation ("Conrex").

                  WHEREAS,  upon the terms and subject to the  conditions of the
Asset  Purchase  Agreement,  dated February 1, 1999 effective as of December 31,
1998, between Conrex and Yungtai Hsu (the "Asset Purchase Agreement"),  in which
Conrex  agreed to sell  certain of its assets to Mr.  Hsu,  Conrex has agreed to
accept 359,282 shares (the "Shares") of common stock,  $0.02 par value per share
(the "Common Stock") of Bentley Pharmaceuticals, Inc. (the "Company") as part of
the Purchase Price (as defined in the Asset Purchase Agreement);

                  WHEREAS,  to induce Conrex to accept the Shares as part of the
Purchase Price,  the Company has agreed to provide certain  registration  rights
under the  Securities  Act of 1933,  as amended,  and the rules and  regulations
thereunder,  or any similar successor statute  (collectively,  the "Act"),  with
respect to the Shares;

                  WHEREAS, as of the date hereof, Conrex and the Company entered
into a  Subscription  Agreement  with  respect to the Shares (the  "Subscription
Agreement");

                  NOW,  THEREFORE,  in  consideration  of the  premises  and the
mutual covenants contained herein and other good and valuable consideration, the
receipt and sufficiency of which are hereby acknowledged, the Company and Conrex
hereby agree as follows:

                  1.       Definitions.

                  (a) As used in this Agreement,  the following terms shall have
the following meanings:

                  (i) "Register,"  "Registered," and  "Registration"  refer to a
registration  effected  by  preparing  and filing a  Registration  Statement  in
compliance with the Act and the declaration or ordering of effectiveness of such
Registration  Statement by the United States Securities and Exchange  Commission
(the "SEC").

                  (ii) "Registrable Securities" means the Shares.

                  (iii) "Registration  Statement" means a registration statement
of the Company under the Act,  including any amendments or  supplements  thereto
and prospectuses contained therein.

                  (iv) "Stockholder"  means Conrex and any permitted  transferee
or assignee who agrees to become bound by the  provisions  of this  Agreement in
accordance with Section 9 hereof.


<PAGE>




                  (b)  Capitalized  terms used herein and not otherwise  defined
herein  shall  have the  respective  meanings  set forth in the  Asset  Purchase
Agreement.

                  2.       Restrictions on Transfer.

                  (a) The Stockholder acknowledges and understands that prior to
the  registration of the Shares as provided  herein,  the Shares are "restricted
securities" as defined in Rule 144 promulgated  under the Act ("Rule 144").  The
Stockholder understands that the Shares may not be offered, transferred, resold,
pledged,  hypothecated or otherwise disposed of in the absence of (i) an opinion
of Parker Chapin Flattau & Klimpl, LLP or other counsel reasonably acceptable to
the Company that such transfer may be made without registration under the Act or
(ii) an  opinion  of  Parker  Chapin  Flattau  &  Klimpl,  LLP or other  counsel
reasonably acceptable to the Company that the Shares have been Registered.

                  (b) The Stockholder  acknowledges  that the Company has issued
the Shares to the Stockholder  pursuant to an exemption from registration  under
the  Act.  Stockholder  represents  that  (i) it has  acquired  the  Shares  for
investment  and  without  any view  toward  distribution  of any of  Registrable
Securities  to any other person,  (ii) it will not sell or otherwise  dispose of
the Shares except in compliance with the registration  requirements or exemption
provisions  under the Act and (iii) before any sale or other  disposition of any
of the Shares other than in a sale registered  under the Act or pursuant to Rule
144 or 144A (or any similar  provisions then in force) under the Act (unless the
Company  shall  have been  advised  by  counsel  that the sale does not meet the
requirements  of Rule 144 or Rule 144A,  as the case may be, for such sale),  it
will  deliver  to the  Company  an opinion  of  counsel,  in form and  substance
reasonably  satisfactory to the Company, to the effect that such registration is
unnecessary.

                  (c) Each instrument or certificate  evidencing or representing
the Shares, and any certificate issued in exchange therefor or transfer thereof,
shall bear legends substantially in the following form:

                  "THE SECURITIES  REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN
                  REGISTERED  UNDER THE  SECURITIES ACT OF 1933, AS AMENDED (THE
                  "ACT") OR APPLICABLE  STATE  SECURITIES  LAWS.  THE SECURITIES
                  HAVE BEEN ACQUIRED FOR INVESTMENT PURPOSES ONLY AND MAY NOT BE
                  OFFERED FOR SALE,  SOLD,  HYPOTHECATED,  ASSIGNED,  PLEDGED OR
                  OTHERWISE   TRANSFERRED   IN  THE  ABSENCE  OF  AN   EFFECTIVE
                  REGISTRATION  STATEMENT  COVERING THE SECURITIES UNDER THE ACT
                  OR APPLICABLE  STATE SECURITIES LAWS, OR AN OPINION OF COUNSEL
                  SATISFACTORY  TO THE ISSUER THAT  REGISTRATION IS NOT REQUIRED
                  UNDER THE ACT OR APPLICABLE STATE SECURITIES LAWS."

                                       -2-

<PAGE>



                  3.  Registration.  The Company shall prepare and file with the
SEC a  Registration  Statement  on  April  1,  1999 or as  soon  as  practicable
thereafter on an appropriate  form for registering for resale by the Stockholder
the  Registrable  Securities  (or such  lesser  number as may be required by the
SEC),  and the  Company  shall use its best  efforts  to cause the  Registration
Statement  to be declared  effective  as soon as  practicable  after filing (the
"Effective  Date").  The rights under this  paragraph  may only be exercised one
time.

                  4.   Obligations  of  the  Company.   In  connection   with  a
registration of the Registrable  Securities under Section 3 hereof,  the Company
shall do each of the following:

                  (a)  Prepare and file with the SEC, a  Registration  Statement
with respect to the Registrable Securities,  and thereafter use its best efforts
to cause each Registration  Statement relating to the Registrable  Securities to
become  effective on the Effective  Date,  and keep the  Registration  Statement
effective at all times until the earliest (the "Registration Period") of (i) the
date  that is two  years  after  the  Closing  Date;  (ii)  the  date  when  the
Stockholder may sell all Registrable Securities under Rule 144 or (iii) the date
the  Stockholder  no  longer  owns  any of  the  Registrable  Securities,  which
Registration Statement shall not contain any untrue statement of a material fact
or omit to state a material fact  required to be stated  therein or necessary to
make the statements  therein,  in light of the  circumstances in which they were
made, not misleading;

                  (b) Prepare and file with the SEC such  amendments  (including
post-effective amendments) and supplements to the Registration Statement and the
prospectus  used  in  connection  with  the  Registration  Statement  as  may be
necessary to keep the Registration  Statement  effective at all times during the
Registration  Period,  and,  during the  Registration  Period,  comply  with the
provisions  of the  Act  with  respect  to the  disposition  of all  Registrable
Securities of the Company covered by the Registration  Statement until such time
as all of such  Registrable  Securities have been disposed of in accordance with
the  intended  methods of  disposition  by the seller or sellers  thereof as set
forth in the Registration Statement;

                  (c)  The  Company  shall  permit  a  single  firm  of  counsel
designated by the Stockholder to review the Registration  Statement a reasonable
period of time prior to the Company's filing of the Registration  Statement with
the SEC;

                  (d)  Furnish  to  the   Stockholder  (i)  promptly  after  the
Registration Statement is prepared and publicly distributed, filed with the SEC,
or  received  by the  Company,  one  copy of the  Registration  Statement,  each
prospectus,  and each amendment or supplement  thereto,  and (ii) such number of
copies of a prospectus,  and all  amendments  and  supplements  thereto and such
other  documents,  as  the  Stockholder  may  reasonably  request  in  order  to
facilitate  the  disposition  of  the  Registrable   Securities   owned  by  the
Stockholder;

                  (e) As promptly as  practicable  after  becoming aware of such
event,  the Company shall notify the  Stockholder of (i) the issuance by the SEC
of a stop order suspending the effectiveness of the Registration Statement, (ii)
the  happening  of any event of which the Company has  knowledge  as a result of
which the prospectus included in the Registration Statement, as then in

                                       -3-

<PAGE>



effect,  includes  an untrue  statement  of a material  fact or omits to state a
material fact required to be stated  therein or necessary to make the statements
therein,  in  light  of the  circumstances  under  which  they  were  made,  not
misleading,  or (iii) the  occurrence  or  existence  of any  pending  corporate
development  that,  in the  reasonable  discretion  of  the  Company,  makes  it
appropriate to suspend the availability of the Registration  Statement,  and use
its  best  efforts  promptly  to  prepare  a  supplement  or  amendment  to  the
Registration Statement to correct such untrue statement or omission, and deliver
such number of copies of such  supplement or amendment to the  Stockholder as it
may reasonably request; provided that, for not more than twenty days (or a total
of not more than forty days in any twelve  month  period,  the Company may delay
the  disclosure of material  non-public  information  concerning the Company (as
well as prospectus or Registration  Statement  updating) the disclosure of which
at the time is not,  in the  good  faith  opinion  of the  Company,  in the best
interests  of the  Company  and in the  opinion of counsel  to the  Company  (an
"Allowed Delay"); provided,  further, that the Company shall promptly (i) notify
the Stockholder in writing of the existence of material  non-public  information
giving rise to an Allowed  Delay and (ii) advise the  Stockholder  in writing to
cease all sales under the  Registration  Statement  until the end of the Allowed
Delay. Upon expiration of the Allowed Delay, the Company shall again be bound by
the first sentence of this Section 4(e) with respect to the  information  giving
rise thereto;

                  (f) As promptly as  practicable  after  becoming aware of such
event,  notify the Stockholder who holds Registrable  Securities being sold (or,
in the event of an  underwritten  offering,  the managing  underwriters)  of the
issuance  by  the  SEC  of  any  notice  declaring  the   effectiveness  of  the
Registration   Statement  or  any  stop  order  or  other   suspension   of  the
effectiveness of the Registration Statement at the earliest possible time; and

                  (g) Take all other  reasonable  actions  necessary to expedite
and facilitate  disposition by the  Stockholder  of the  Registrable  Securities
pursuant to the Registration Statement.

                  5.  Obligations  of the  Stockholder.  In connection  with the
registration  of the  Registrable  Securities,  the  Stockholder  shall have the
following obligations:

                  (a) It shall be a condition  precedent to the  obligations  of
the Company to complete the registration pursuant to this Agreement with respect
to the  Registrable  Securities of the Stockholder  that the  Stockholder  shall
furnish to the  Company  such  information  regarding  itself,  the  Registrable
Securities held by it, and the intended method of disposition of the Registrable
Securities  held  by  it,  as  shall  be  reasonably   required  to  effect  the
registration of such Registrable  Securities and shall execute such documents in
connection  with such  registration  as the Company may reasonably  request.  At
least five days prior to the first  anticipated  filing date of the Registration
Statement,  the Company  shall notify the  Stockholder  of the  information  the
Company  requires from the  Stockholder  (the  "Requested  Information")  if the
Stockholder  elects  to have  any of the  Stockholder's  Registrable  Securities
included in the  Registration  Statement.  If at least three  Business  Days (as
defined  below)  prior to the  filing  date the  Company  has not  received  the
Requested  Information  from  the  Stockholder,  then the  Company  may file the
Registration   Statement  without  including   Registrable   Securities  of  the
Stockholder;

                                       -4-

<PAGE>



                  (b)  The   Stockholder   by  acceptance  of  the   Registrable
Securities  agrees to cooperate with the Company as reasonably  requested by the
Company  in  connection  with the  preparation  and  filing of the  Registration
Statement hereunder,  unless the Stockholder has notified the Company in writing
of the Stockholder's  election to exclude all of its Registrable Securities from
the Registration Statement; and

                  (c) The  Stockholder  agrees that,  upon receipt of any notice
from the Company of the happening of any event of the kind  described in Section
4(e) or 4(f), above, the Stockholder will immediately discontinue disposition of
Registrable  Securities  pursuant to the  Registration  Statement  covering such
Registrable  Securities  until the  Stockholder's  receipt  of the copies of the
supplemented or amended prospectus  contemplated by Section 4(e) or 4(f) and, if
so directed by the Company, the Stockholder shall deliver to the Company (at the
expense of the Company) or destroy (and deliver to the Company a certificate  of
destruction)  all  copies in the  Stockholder's  possession,  of the  prospectus
covering  such  Registrable  Securities  current  at the time of receipt of such
notice.

                  6.       Expenses of Registration.

                  (a)  All  reasonable  expenses,  other  than as set  forth  in
Section  6(b)  hereof,  filings  or  qualifications  pursuant  to Section 4, but
including,  without limitation,  all registration,  listing,  and qualifications
fees,  printers and accounting  fees, the fees and  disbursements of counsel for
the Company, shall be borne by the Company.

                  (b) All  underwriting  discounts and  commissions  incurred in
connection with registrations shall be paid by the Stockholder.

                  7.  Indemnification.  Conrex shall indemnify and hold harmless
the Company and each officer, director or control person of any such entity, who
is or may be a  party  or is or may be  threatened  to be  made a  party  to any
threatened,  pending or completed  action,  suit or  proceeding,  whether civil,
criminal,  administrative or investigative, by reason of or arising from (i) any
actual or alleged  misrepresentation  or  misstatement  of facts or  omission to
represent  or state  facts  made or  alleged  to have been made by Conrex to the
Company, (or its agents or representatives),  or omitted or alleged to have been
omitted  by  Conrex,  concerning  Conrex,  or  Conrex's  authority  to invest or
financial position in connection with the offering or sale of the Shares in this
Agreement,  in the  Subscription  Agreement or elsewhere,  or (ii) any breach of
warranty or failure to comply with any covenant  contained in this  Agreement or
in  the  Subscription  Agreement,   including,   without  limitation,  any  such
misrepresentation,  misstatement  or  omission,  or  breach of any  warranty  or
covenant,  contained herein or any other document  submitted by Conrex,  against
losses,  liabilities  and  expenses  for which  the  Company,  or its  officers,
directors  or control  persons  has not  otherwise  been  reimbursed  (including
attorneys'  fees,  judgments,  fines and amounts paid in  settlement  in matters
settled in accordance with the provision of the following paragraph) incurred by
the Company, or such officer, director or control person in connection with such
action, suit or proceeding; provided, however, that Conrex will not be liable in
any such case for losses, claims, damages,  liabilities or expenses that a court
of competent jurisdiction shall have found in a final judgment to have arisen

                                       -5-

<PAGE>



primarily from the gross negligence or willful  misconduct of the Company or the
party claiming a right to indemnification.

                  In case any  proceeding  shall  be  instituted  involving  any
person  with  respect  to  whom  indemnity  may  be  sought,  such  person  (the
"Indemnified  Party") shall promptly notify Conrex, and Conrex, upon the request
of the Indemnified Party,  shall retain counsel  reasonably  satisfactory to the
Indemnified  Party to represent the Indemnified  Party and any others Conrex may
designate in such proceedings and shall pay as incurred the fees and expenses of
such counsel related to such proceeding. In any such proceeding, any Indemnified
Party shall have the right to retain its own counsel at its own expense,  except
that Conrex shall pay as incurred  the fees and expenses of counsel  retained by
the  Indemnified  Party in the event that (i) Conrex and the  Indemnified  Party
shall have  mutually  agreed to the retention of such counsel or, (ii) the named
parties to any such proceeding  (including any impleaded  parties)  include both
Conrex and the Indemnified Party and  representation of both parties by the same
counsel would be  inappropriate,  in the reasonable  opinion of the  Indemnified
Party, due to actual or potential differing interests between them. Conrex shall
not be liable for any settlement of any proceeding  effected without its written
consent,  but if settled with such  consent or if there be a final  judgment for
the plaintiff,  Conrex agrees to indemnify the  Indemnified  Party to the extent
set forth in this Agreement.

                  In the event a claim for  indemnification  as described herein
is determined to be  unenforceable  by a final  judgment of a court of competent
jurisdiction,  then Conrex shall  contribute  to the aggregate  losses,  claims,
damages or liabilities to which the Company or its officers,  directors, agents,
employees or controlling persons may be subject in such amount as is appropriate
to reflect the relative  benefits  received by each of the  undersigned  and the
party seeking contribution on the one hand and the relative faults of Conrex and
the party seeking  contribution on the other, as well as any relevant  equitable
considerations.

                  The provisions of this Agreement  relating to  indemnification
and  contribution  shall  survive  termination  of this  Agreement  and shall be
binding upon any successors or assigns of Conrex.

                  8.  Termination  of  Registration  Rights.  The rights granted
pursuant  to this  Agreement  shall  terminate  as to the  Stockholder  upon the
occurrence of any of the following:

                  (a) all of the Registrable Securities have been registered; or

                  (b) all of the Registrable Securities may be sold without such
registration pursuant to Rule 144.

                  9.       Miscellaneous.

                  (a) A person or entity is deemed to be a holder of Registrable
Securities  whenever  such  person or entity  owns of  record  such  Registrable
Securities.  If  the  Company  receives  conflicting  instructions,  notices  or
elections from two or more persons or entities with respect to the same

                                       -6-

<PAGE>



Registrable  Securities,  the Company shall act upon the basis of  instructions,
notice  or  election  received  from the  registered  owner of such  Registrable
Securities.

                  (b) Notices.  All notices,  demands or other communications to
be given or delivered  under or by reason of the  provisions  of this  Agreement
shall be in writing  and shall be deemed to have been  given (a) when  delivered
personally to the recipient, (b) when sent to the recipient by telecopy (receipt
electronically confirmed by sender's telecopy machine) if during normal business
hours of the recipient, otherwise on the next Business Day ("Business Day" means
a day other than Saturday, Sunday or any day on which banks located in the State
of New York are  authorized  or obligated to close),  (c) one Business Day after
the date  when  sent to the  recipient  by  reputable  express  courier  service
(charges  prepaid) or (d) seven  Business Days after the date when mailed to the
recipient by certified or registered mail,  return receipt requested and postage
prepaid.  Such notices,  demands and other communications will be sent to Conrex
and to the Company at the addresses indicated below.

                  If to Conrex, to:

                           Conrex Pharmaceutical Corporation
                           5127 West Chester Pike
                           Newtown Square, Pennsylvania 19073
                           Attention:  Phyllis Hsieh
                           Facsimile No.: (610) 355-2453

                  with a copy to:

                           Synnestvedt & Lechner LLP
                           Suite 2600 Aramark Tower
                           1101 Market Street
                           Philadelphia, PA 19107
                           Attention: John T. Synnestvedt
                           Facsimile No.: (215) 923-2189

                  If to the Company, to:

                           Bentley Pharmaceuticals, Inc.
                           Two Urban Centre, Suite 400
                           4890 West Kennedy Blvd.
                           Tampa, Florida 33609
                           Attention:  James R. Murphy
                           Facsimile No.:  (813) 282-8941

                                       -7-

<PAGE>



                  With a copy to:

                           Parker Chapin Flattau & Klimpl, LLP
                           1211 Avenue of the Americas
                           New York, New York 10036
                           Attention:  Mark S. Hirsch
                                       Jordan A. Horvath
                           Facsimile:  (212) 704-6288


                  (c) Assignment; Benefit. This Agreement may not be assigned by
Conrex  without the prior  written  consent of the  Company  and any  assignment
without  such consent  shall be void.  The rights  under this  Agreement  may be
assigned by Conrex to its  Stockholders if Conrex  distributes the Shares to its
Stockholders  as a dividend  to the extent  the Shares are  distributed  to each
Stockholder, provided that such Stockholders agree to be bound by all provisions
of this Agreement and all such  transfers are in accordance  with all applicable
laws. Upon such  assignment  Conrex and its  Stockholders  will have the various
rights under this  Agreement  which  pertain to the Shares then owned by each of
them.  This  Agreement  may be  assigned  by the Company to any person or entity
which purchases all or  substantially  all of the stock or assets of the Company
or is the successor to the Company by merger or  consolidation.  This  Agreement
shall be binding upon and inure to the benefit of the respective  successors and
permitted assigns of the Company and of Conrex.

                  (d) Severability.  The invalidity or  unenforceability  of any
provisions of this Agreement shall not affect the validity or  enforceability of
any other provision of this Agreement,  each of which shall remain in full force
and effect.

                  (e) Amendments. This Agreement may be amended, supplemented or
modified,  and any  provision  hereof may be waived,  only pursuant to a written
instrument  making  specific  reference to this Agreement  signed by each of the
parties hereto.

                  (f) Counterparts. This Agreement may be executed in any number
of  counterparts,  each of which shall be deemed an  original,  but all of which
together shall constitute one and the same instrument.

                  (g)  Governing  Law. This  Agreement  shall be governed by and
construed in accordance  with the laws of the State of New York  applicable to a
contract  executed and  performed  in such State  without  giving  effect to the
conflicts  of laws  principles  thereof,  except that if it is  necessary in any
other  jurisdiction  to have  the law of such  other  jurisdiction  govern  this
Agreement in order for this  Agreement to be effective in any respect,  then the
laws of such other jurisdiction shall govern this Agreement to such extent.

                                       -8-

<PAGE>



                  (h)      Arbitration of Disputes

                                    (i) If any  controversy  or  dispute  arises
under, out of or in relation to any of the provisions  hereof,  such controversy
or dispute shall be submitted  for  arbitration  in New York,  New York before a
panel of  three  arbitrators,  one of  which  shall  be  selected  by the  party
initiating such  arbitration,  one of which shall be selected by the other party
and the third of which (the  "Third  Arbitrator")  shall be  selected by the two
arbitrators so selected;  provided,  however,  that in the event that such other
arbitrators shall not agree on the selection of the Third Arbitrator,  the Third
Arbitrator shall be selected by the American Arbitration  Association located in
New York,  New York.  Any dispute or  controversy  submitted to  arbitration  in
accordance  with the  provisions  of this Section  shall be  determined  by such
arbitrators in accordance with the Commercial  Arbitration Rules of the American
Arbitration Association then existing.

                                    (ii) The  arbitrators  may award any  relief
which they shall deem proper in the circumstances,  without regard to the relief
which  would  otherwise  be  available  to any party in a court of law or equity
including,  without limitation, an award of money damages, specific performance,
injunctive  relief and/or  declaratory  relief,  however,  such an award may not
include  punitive  damages.  The award and findings of the arbitrators  shall be
conclusive  and  binding  upon all of the  parties  hereto,  whether  or not all
parties hereto participate in the arbitration proceeding,  and judgment upon the
award may be entered in any court of competent jurisdiction upon the application
of  any  party.   The  parties  hereby  agree  that  such  courts  of  competent
jurisdiction  shall  include,  but not be limited to, the courts  located in any
jurisdiction  in which the party  against whom such  judgment is being  enforced
maintains any assets.

                                    (iii) The costs of the  arbitration and each
party's associated costs shall be borne by the losing party. Notwithstanding the
foregoing, if the parties reach a compromise, the costs of the arbitration shall
be borne  equally by the parties  and each party  shall bear its own  associated
costs.

                                    (iv)  Notwithstanding  the  foregoing,   the
parties reserve the right to seek and obtain injunctive  relief,  whether in the
form of a temporary  restraining order,  preliminary  injunction,  injunction to
enforce an arbitration award, or other order of similar import, from the federal
and state  courts  located  in New York,  New York  prior to,  during,  or after
commencement or prosecution or arbitration proceedings of the final decision and
award of the arbitrators;  provided,  however, that such preliminary  injunctive
relief shall be subject to final arbitral decisions.

                                    (v) Each party  hereby  consents  and agrees
that the federal and state courts  located in New York, New York each shall have
exclusive personal jurisdiction and proper venue with respect to any such action
seeking  injunctive  or similar  relief  hereunder.  In any dispute  between the
parties,  neither party will raise, and each party hereby expressly waives,  any
objection  or  defense to any such court as an  inconvenient  forum.  Each party
hereby waives personal service of any summons, complaint or other process, which
may be delivered by any of the means  permitted  for notices under Section 10(b)
hereof

                                       -9-

<PAGE>


                  IN WITNESS  WHEREOF,  the parties have  executed and delivered
this Agreement as of the day and year first written above.

                                         BENTLEY PHARMACEUTICALS, INC.


                                         By:  /s/ James R. Murphy
                                             -----------------------------------
                                            James R. Murphy, Chairman, President
                                               and Chief Executive Officer

                                         CONREX PHARMACEUTICAL CORPORATION


                                         By:  /s/  Phyllis Hsieh
                                              ----------------------------------
                                                 Phyllis Hsieh, President



                                      -10-


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