BIO IMAGING TECHNOLOGIES INC
10KSB, 1999-12-29
MEDICAL LABORATORIES
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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
                              --------------------
                                  FORM 10-KSB

                   ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF
                       THE SECURITIES EXCHANGE ACT OF 1934

                  For the fiscal year ended September 30, 1999
                           Commission File No. 1-11182

                         BIO-IMAGING TECHNOLOGIES, INC.
              ----------------------------------------------------
             (Exact Name of Registrant as Specified in Its Charter)

          Delaware                                        11-2872047
- -----------------------------               ------------------------------------
(State or Other Jurisdiction                (I.R.S. Employer Identification No.)
of Incorporation or Organization)


830 Bear Tavern Road, West Trenton, New Jersey                     08628-1020
- --------------------------------------------------------------------------------
(Address of Principal Executive Offices)                            (Zip Code)

                                 (609) 883-2000
                         -------------------------------
                         (Registrant's Telephone Number,
                              Including Area Code)

           Securities registered pursuant to Section 12(b) of the Act:

    Title of each class                Name of each exchange on which registered
    -------------------                -----------------------------------------

Common Stock, $.00025 par              Boston Stock Exchange
value per share


         Securities registered under Section 12(g) of the Exchange Act:

                                      None

<PAGE>

        Check whether the Registrant: (1) filed all reports required to be filed
by Section 13 or 15(d) of the Securities  Exchange Act during the past 12 months
(or for such  shorter  period  that the  Registrant  was  required  to file such
reports),  and (2) has been subject to such filing  requirements for the past 90
days.

                    Yes:                         No: X
                         ----                       ----


     Check if there is no disclosure  of  delinquent  filers in response to Item
405 of  Regulation  S-B  contained  in  this  form,  and no  disclosure  will be
contained,  to the  best of  Registrant's  knowledge,  in  definitive  proxy  or
information statements incorporated by reference in Part III of this Form 10-KSB
or any amendment to this Form 10-KSB. [X]

     State  Registrant's  revenues  for fiscal year ended  September  30,  1999:
$4,349,079

     State the aggregate market value of the voting stock held by non-affiliates
of the Registrant:  $1,565,328 at November 30, 1999 based on the average bid and
asked prices on that date.


     Indicate  the  number of  shares  outstanding  of each of the  Registrant's
classes of common stock, as of November 30, 1999:

Class                                                        Number of Shares
- -----                                                        ----------------

Common Stock, $.00025 par value                                  7,773,878


     Transitional Small Business Disclosure Format

                    Yes:                         No: X
                         ----                       ----


     The  following  documents  are  incorporated  by reference  into the Annual
Report on Form 10-KSB:  Portions of the Registrant's  definitive Proxy Statement
for its 2000 Annual Meeting of Stockholders  are  incorporated by reference into
Part III of this Report.



<PAGE>

                                TABLE OF CONTENTS
                                -----------------

          Item                                                            Page
          ----                                                            ----

PART I    1.   Business.....................................................1

          2.   Properties...................................................9

          3.   Legal Proceedings............................................9

          4.   Submission of Matters to a Vote of Security Holders..........9

PART II   5.   Market for the Company's Common Equity and Related
               Stockholder Matters.........................................10

          6.   Management's Discussion and Analysis of Financial
               Condition and Results of Operations.........................12

          7.   Financial Statements........................................19

          8.   Changes in and Disagreements with Accountants on
               Accounting and Financial Disclosure.........................19

PART III  9.   Directors, Executive Officers, Promoters and Control
               Persons; Compliance with Section 16 (a) of the
               Exchange Act................................................20

          10.  Executive Compensation......................................20

          11.  Security Ownership of Certain Beneficial Owners
               and Management..............................................20

          12.  Certain Relationships and Related Transactions..............20

          13.  Exhibits, List and Reports on Form 8-K......................20

SIGNATURES.................................................................21

EXHIBIT INDEX..............................................................23

FINANCIAL STATEMENTS......................................................F-1





                                       -i-
<PAGE>

                                     PART I


ITEM 1.   BUSINESS.

GENERAL


     Bio-Imaging  Technologies,  Inc.  ("Bio-Imaging"  or  "the  Company")  is a
pharmaceutical  contract service  organization,  providing services that support
the product development process of the pharmaceutical, biotechnology and medical
device  industries.  The Company  specializes  in  assisting  its clients in the
design and management of the  medical-imaging  component of clinical  trials for
all  modalities  which  consist  of  computerized  tomography  ("CT"),  magnetic
resonance imaging ("MRI"),  x-rays, dual energy x-ray  absorptiometry  ("DEXA"),
position  emission  tomography  single photon emission  computerized  tomography
("PET SPECT") and ultrasound.  The Company  provides  services which include the
processing  and analysis of medical  images and the  data-basing  and regulatory
submission of medical images, quantitative data and text.

     The Company  utilizes  proprietary  processes and software  applications in
providing its services to pharmaceutical  companies  conducting clinical studies
in which medical imaging modalities are used to evaluate the efficacy and safety
of  pharmaceuticals,  biologics or medical devices.  The Company's digital image
processing  and computer  analysis  techniques  enable it to make highly precise
measurements and  biostatistical  inferences  about drug or device effects.  The
resulting  data enable the Company's  clients,  and their  regulatory  reviewers
(primarily  the U.S.  Food and  Drug  Administration,  the  "FDA"  and  European
Agencies) to evaluate product efficacy and safety. In addition,  the Company has
developed  specialized  computer services and software  applications that enable
independent  radiologists  and other  medical  specialists  involved in clinical
trials to review medical image data in an entirely digital format.

     The  Company  continues  to believe  that it is at an early stage of market
penetration  and is directing  its  marketing  and sales  efforts  towards those
clinical development areas that heavily depend upon medical imaging. These areas
include therapeutic and diagnostic anti-inflammatory,  oncology, central nervous
system, osteoporosis and cardiovascular.

     In February  1997, the Company  opened a European  facility in Leiden,  the
Netherlands  to provide  centralized  image  processing  services  for  European
clients.  The Company  manages its services for European based  clinical  trials
from this facility. The Company's European facility has the same capabilities as
the Company's U.S. headquarters.

     In May 1999, the Company  acquired the operations of Bona Fide, Ltd. ("Bona
Fide").  Bona Fide provides DEXA quality assurance and quality control ("QA/QC")
to the  pharmaceutical  and medical device  industry for studies  requiring bone
densitometry and body composition measurements.

     The  Company  was  incorporated  in  Delaware  in 1987  under the name Wise
Ventures, Inc. The Company's name was changed to Bio-Imaging Technologies,  Inc.
in 1991. The address of the Company's  principal  executive  offices is 830 Bear
Tavern Road,  West  Trenton,  New Jersey,  08628,  and its  telephone  number is
609-883-2000.


                                      -1-
<PAGE>

BUSINESS SERVICES

     Core Laboratory Services

     Bio-Imaging is a leading  provider of medical imaging  management  services
for  clinical  development  purposes.  The  Company's  imaging  core  laboratory
facilities in the U.S.A. and Europe provide  centralized  image data collection,
processing,  analysis  and  archival  services  for  clinical  trials  conducted
worldwide.  The facilities are designed for high-volume  efficient processing of
analog (film) and digital image data in a secure  environment that complies with
regulatory guidelines for clinical data management.

     Medical  image data are received by  Bio-Imaging  facilities  from clinical
trial  sites,  typically  academic  or  community  hospitals.  The  Company  has
developed  procedures for data tracking and quality  control that it believes to
be of  significant  value  to its  clients.  The  Company's  facilities  contain
specialized  hardware and software for the digitization of films and translation
of digital data, enabling data to be standardized, regardless of its source. The
Company  believes its ability to handle most  commercially  available image file
formats is a valuable technical asset and an important  competitive advantage in
gaining new business for large global multi-center clinical trials.

     The  Company  performs  image  analyses  on client  data  using  internally
developed or specially configured software.  The Company measures key indicators
of drug efficacy in different organs and disease states.  The results from image
analysis derived in Bio-Imaging facilities are transferred to databases that can
be transmitted  electronically to the Company's clients,  or integrated directly
into the Company's  Bio/ImageBase(R)  package for  regulatory  submission on the
client's behalf.

     Information Management Services

     Bio-Imaging's   information   management   services   focus  on   providing
specialized solutions for improving the quality,  speed and flexibility of image
data  management for clinical  trials.  The Company's  Computer  Assisted Masked
Reading   ("CAMR(TM)")  systems  offer  numerous  advantages  over  conventional
film-based medical image reading scenarios,  including  increased reading speed,
greater  standardization  of image reading,  and reduced error in the capture of
reader interpretations.

     Using the Company's CAMR(TM) systems,  independent  medical specialists can
review medical image data from clinical trials in a digital format. The CAMR(TM)
systems can display all  modalities of medical image data,  regardless of source
equipment.  In addition,  the systems can display either translated digital data
or digitized films. Such image reviews are often required during clinical trials
to evaluate patients'  responses to therapy, or to determine if patients qualify
for  studies.  By using the CAMR(TM)  systems to read and  evaluate  image data,
medical  specialists  can achieve  greater  reading  speed than is possible with
film, and can perform evaluations in a more objective, reproducible manner.



                                      -2-
<PAGE>

     The Company has also developed remote CAMR(TM)  ("rCAMR(TM)") systems which
are  located on the  premises  of the  individual  medical  specialists  who are
engaged by the sponsor to perform the analysis of the medical  image data.  More
recently,  clients are requesting  Bio-Imaging to provide  "real-time" reads for
inclusion/exclusion  criteria,  or safety reads.  The Company  believes that the
rCAMR(TM)  system is the  optimal  tool for this type of work  because it allows
Bio-Imaging,  at the client's discretion,  to provide the images to an expert in
the field to  facilitate  the review of the images from the  expert's  office or
home.

     The  Company  has  developed  a   proprietary   image   database   software
application,  Bio/ImageBase(R),  that  enables the  Company's  clients to submit
their medical images and related  clinical data to the FDA in a digital  format.
Using data stored on CD-ROM disks, Bio/ImageBase(R) allows clients and their FDA
medical  reviewers  to review  medical  images and related  clinical  data.  The
Company believes that  Bio/ImageBase(R)  offers the potential to decrease review
time,  resulting in faster regulatory  approvals and reduced  time-to-market for
new drugs, biologics and medical devices.

     The Company's  Bio/ImageBase(R) software has been installed at client sites
and on certain  computer  systems  at the FDA.  The  Company  has been using its
Bio/ImageBase(R)  software to submit  medical images and related data to the FDA
since  mid-1993.  In March  1996,  Bio/ImageBase(R)  was cited in the FDA's 1996
Computer-Assisted  Product License Application  Guidance Manual as an acceptable
database for submission of imaging data.

     Other Services

     The Company  provides  technical  consulting in the evaluation of the sites
that may participate in clinical trials.  The Company also consults with clients
regarding  regulatory  issues  involved in the design,  execution,  analysis and
submission of medical image data in clinical trials.

TARGET MARKETS

     The  Company's  primary  target  market  is  comprised  of  pharmaceutical,
biotechnology and medical device companies whose clinical development  pipelines
include  drugs,  biologics  or devices that are  typically  evaluated by medical
imaging   methods.   This   target   market   includes   leading   international
pharmaceutical  companies and biotechnology companies with products currently in
the clinical development pipeline.

     Bio-Imaging  focuses  its  marketing  on the  following  stages of clinical
development:

     Phase II Clinical Trials

     Phase II clinical  trials are  generally  conducted  over six months to two
years and involve basic efficacy (effectiveness),  safety and dose-range testing
in  approximately  50 to 400  patients  suffering  from the disease or condition
under study.  Such trials help determine the best effective  dose,  confirm that
the drug works as expected and provide initial safety data.



                                      -3-
<PAGE>

     Phase III Clinical Trials

     Phase III clinical  trials are generally  conducted  over one to four years
and involve  efficacy and safety  studies in broader  populations of hundreds or
thousands of patients and many  investigational  sites  (hospitals and clinics).
These are  sometimes  referred  to as  pivotal  studies  for  submission  to the
regulatory  agencies.  Generally,  Phase III  studies  are  intended  to provide
additional  information  on drug  safety  and  efficacy,  an  evaluation  of the
risk-benefit  of the drug  and  information  for the  adequate  labeling  of the
product.

     Bio-Imaging  focuses its marketing  efforts  further on clinical trials for
the following classes of drugs:

     Anti-Inflammatory Therapeutics

     Anti-inflammatory  clinical  trials,  such as those  focused on  arthritis,
include  radiologic  evaluation  of the  bones  and  joints  to  determine  drug
efficacy.  The  Company  believes  that  demand  among drug  developers  for its
services will increase as new classes of  biotechnology-derived  drugs enter and
progress through the clinical development pipeline.

     Cancer Therapeutics

     Many  pharmaceutical  companies are currently  developing new therapies for
the treatment of cancer. For solid tumor studies, medical imaging modalities are
used to determine  the response of treated and untreated  tumors.  These medical
images are  evaluated  by  medical  specialists  during  the course of  oncology
clinical  trials to  determine  the extent of disease  and changes in tumor size
over time.

     The  FDA's  guidelines  aimed at  accelerating  access to new drugs for the
review and approval of new cancer  therapies place greater emphasis on shrinkage
of tumors as an early  indicator of anti-tumor  efficacy.  Bio-Imaging  believes
that  these  FDA  guidelines  may have a  favorable  impact on its  business  as
pharmaceutical  and  biotechnology  companies  may  have an  increased  need for
regulatory compliant medical imaging services to conduct their oncology clinical
trials.

     Central Nervous System Therapeutics

     Various  pharmaceutical   companies  are  currently  developing  drugs  for
treatment of diseases and  conditions  of the central  nervous  system,  most of
which are evaluated with the aid of medical imaging.  Most later-stage  clinical
trials for these serious and costly conditions involve the evaluation of medical
image data. The Company believes that its central nervous system clinical trials
business may increase as more therapies progress through the research pipeline.



                                      -4-
<PAGE>

     Osteoporosis

     Osteoporosis is the disease of "thinning bones" which leads to fractures in
the  elderly.  The FDA  guidance  document for  developing  treatments  for this
disease  recognized DEXA as one of the primary  efficacy and safety  measurement
tools available.  Furthermore,  all data needs to go through a quality assurance
laboratory.  This is now standard practice in all studies using DEXA instruments
whether for osteoporosis oncology or antiobesity or muscle wasting asssessment.

     Diagnostic Imaging Agents

     Bio-Imaging provides its services to clients developing  diagnostic imaging
agents  which are  designed  to diagnose  disease  conditions  more  quickly and
accurately in their development in order to facilitate earlier and more accurate
treatment.

     Cardiovascular Therapeutics

     Various  pharmaceutical  companies are currently  developing  drugs for the
diagnosis  and treatment of  cardiovascular  diseases and  conditions  which are
evaluated with the aid of medical imaging.  The Company provides its services to
clients  developing  diagnostic  agents for the detection and treatment of these
conditions.

MARKET TRENDS

     The Company  believes that demand for its services should grow because of a
variety of favorable regulatory, technological and market trends:

     o     The FDA  initiatives  to streamline  the  regulatory  submission  and
           review process which are being  implemented  should have a beneficial
           impact  on the  Company.  The  FDA is  investing  in new  information
           technology and has begun the process of formulating and disseminating
           guidelines  for  standardizing  the  submission of  electronic  data,
           including  medical images.  The Company  expects  submission of image
           data to be a requirement in key therapeutic and diagnostic  areas for
           evaluating the effectiveness of a drug or imaging agent.

     o     Consolidation,  restructuring  and  downsizing in the  pharmaceutical
           industry in response to downward  pressure on certain  pharmaceutical
           and  biotechnology  companies'  drug prices has resulted in increased
           outsourcing   of  certain   research  and   development   activities.
           Currently,  over $4 billion in research  services are  outsourced  to
           contract clinical research  organizations.  Industry  estimates place
           growth of  outsourcing  between  20% to 30% per year for at least the
           next three years.

     o     Growth in pharmaceutical  and biotechnology  research and development
           spending is fairly  non-cyclical.  As a result,  the Company believes
           that outsourcing of development  activities should continue to remain
           steady.



                                      -5-
<PAGE>

     o     New classes of drugs to treat conditions  traditionally  evaluated by
           imaging are entering or progressing through the clinical  development
           pipeline,  leading to  increased  demand for medical  imaging-related
           services. In addition,  digital technologies for data acquisition and
           management are rapidly penetrating the radiology community.

     o     As pharmaceutical and biotechnology companies increasingly attempt to
           expand  the market for new drugs by  conducting  clinical  trials and
           pursuing  regulatory  approval in multiple countries  simultaneously,
           contract service  organizations  with an  international  presence and
           expertise  will  continue  to  benefit.  The  Company  believes it is
           well-positioned to take advantage of these trends due to its U.S. and
           European operations.

     o     The Company also believes that, because its development  services are
           specialized, it is often able to perform these services with a higher
           level of expertise  or  specialization  more quickly and  efficiently
           than  a  pharmaceutical   or  biotechnology   company  could  perform
           internally.

INTELLECTUAL PROPERTY

     Proprietary  protection  for  the  Company's   computer-imaging   programs,
processes and know-how is important to its business.  Bio-Imaging  has developed
certain technically  derived procedures and computer software  applications that
are  intended to increase the  effectiveness  and quality of its  services.  The
Company  relies  upon  trademarks,   copyrights,  trade  secrets,  know-how  and
continuing  technological  innovation  to develop and maintain  its  competitive
position.  The Company has  obtained  registered  trademark  protection  for the
Bio/ImageBase(R)  and has claimed  trademark  protection  for the  CAMR(TM)  and
rCAMR(TM).  The Company also has applied for patent  protection for the two DEXA
phantoms  it  sells  to  trial  sites.  Furthermore,  Bio-Imaging  requires  all
employees,  consultants  and  contractors  to  execute  confidential  disclosure
agreements as a condition of employment or engagement by the Company.  There can
be no assurance,  however,  that the Company can limit  unauthorized or wrongful
disclosures of trade secret information.  In addition, to the extent the Company
relies on trade secrets and know-how to maintain its  competitive  technological
position,  there can be no assurance  that others may not develop  independently
the same or similar  techniques.  Although the Company's  intellectual  property
rights are important to the results of its operations, the Company believes that
other factors such as independence,  process knowledge,  technical expertise and
experience  are  more  important,   and  that,   overall,   these  technological
capabilities offer significant benefits to its clients.

GOVERNMENT REGULATION

     The  research  and  development,  manufacture  and  marketing  of drugs and
medical  devices are subject to  stringent  regulation  by the FDA in the United
States  and  by  comparable   authorities  in  other  countries.   In  addition,
regulations  imposed  by other  federal  agencies,  as well as state  and  local
authorities,  may  impact  such  research  and  development,  manufacturing  and
marketing.



                                      -6-
<PAGE>

     The FDA has  established  mandatory  procedures and safety  standards which
apply to the clinical testing,  manufacturing and marketing of drugs and medical
devices.  These procedures and safety standards include, among other things, the
completion of adequate and  well-controlled  human clinical  trials to establish
the safety and efficacy of the drug or device for its recommended  conditions or
use. The Company  advises its clients in the  execution  of clinical  trials and
other drug and device developmental tasks. The Company does not administer drugs
to or utilize medical devices on patients.

     The success of the  Company's  business  is  dependent  upon the  continued
acceptance by the FDA and other regulatory authorities which review the data and
analyses generated by the Company's services in the evaluation of the safety and
efficacy of new drugs and devices. The FDA has formal guidelines which encourage
the use of "surrogate  measures,"  through submission of digital image data, for
evaluation of drugs to treat life-threatening or debilitating conditions.  There
can be no assurance,  however, that the FDA or other regulatory authorities will
accept the data or analyses  generated  by the  Company in the future and,  even
assuming acceptance,  there can be no assurance that the FDA or other regulatory
authorities  will require the  application  of imaging  techniques to numbers of
patients  and over time  periods  substantially  similar  to those  required  of
traditional safety and efficacy techniques.

     Changes in the FDA's  policy for the  evaluation  of  therapeutic  oncology
agents  may have a positive  impact on the time to market of such  therapeutics.
According  to the  guidelines  announced in March 1996,  approval  times for new
cancer  therapies can be shortened if evidence of tumor  shrinkage is verifiable
and  demonstrable  through the use of objective  measurement  techniques.  These
guidelines  place much  greater  reliance  on the use of  medical  image data to
demonstrate  objective  tumor  shrinkage.  In addition,  in March 1997,  the FDA
announced  new  guidelines  aimed at  accelerating  all  therapeutic  categories
through the use of  surrogate  markers  such as imaging  endpoints.  The Company
believes the FDA's  initiatives  to streamline and accelerate the submission and
review  process  of  therapeutic  agents  may  have a  favorable  impact  on the
Company's business.

     In October 1998, the FDA released a draft guidance for industry relating to
how medical imaging should be defined, handled and evaluated in clinical trials.
The Company believes that the guidance  document comports with the methodologies
and  processes  utilized  by  the  Company  in  providing  medical   information
management services for its clients.

     The Company believes that its ability to achieve  continued and sustainable
growth will be materially  dependent  upon,  among other factors,  the continued
stringent  enforcement  of the  comprehensive  regulatory  framework  by various
government agencies. Any significant change in these regulatory  requirements or
the enforcement  thereof,  especially  relaxation of standards,  could adversely
affect the Company's prospects.

     The current  European  market  regulation  is more  fragmented  than in the
U.S.A.,  therefore,  such  European  agencies  have a  tendency  to  follow  FDA
guidelines.



                                      -7-
<PAGE>

COMPETITION

     As a sign of growth in the clinical trials-related medical imaging services
business,  the Company  continues to experience an increase in competition  from
commercial  competitors and academic research centers.  Over the past two years,
several  conventional  contract  research  organizations  have either started or
acquired  divisions  to address  the need for  medical  imaging  services  as it
relates to clinical trials. As competition  increases,  Bio-Imaging will look to
provide  value-added  services and  undertake  marketing  and sales  programs to
differentiate  its services  based on its expertise  and  experience in specific
therapeutic and diagnostic areas, its technological expertise and regulatory and
clinical development  experience,  its quality performance and its international
capabilities.  Competition in the Company's  industry has resulted in additional
pressure  being  placed on price,  service  and  quality.  Although  the Company
believes  that  it is  well  positioned  against  its  competitors  due  to  its
experience  in  clinical  trials  and  regulatory   compliance  along  with  its
international presence, there can be no assurance that the Company's competitors
or clients  will not  provide or develop  services  similar or superior to those
provided by the  Company.  Any such  competition  could have a material  adverse
impact on the Company. The Company's  competitive position also depends upon its
ability to attract and retain  qualified  personnel  and  develop  and  preserve
proprietary technology, processes and know-how.

MARKETING AND SALES

     Bio-Imaging  provides  and markets its services on an  international  basis
primarily to pharmaceutical and biotechnology companies. The Company's sales and
marketing activities are performed by a Vice President,  Business Development, a
Director  of  Client  Technical  Services,  three  Regional  Managers  of Client
Technical Services, a Director of Clinical Services-Europe,  a Manager, Business
Development and a Business Development Associate.

     The  Company's  selling  efforts are  focused on North  America and Western
Europe.  Sales efforts are directed from both of the Company's  headquarters  in
New Jersey and Leiden,  the  Netherlands.  The  Company's  marketing  activities
include  exhibiting at major trade shows,  advertising in trade journals and the
sponsoring  of  industry   associations.   The  Company  continues  to  evaluate
appropriate  co-marketing activities and strategic alliances, in particular with
contract  research  organizations,  to  augment  its  own  business  development
efforts.

SIGNIFICANT CLIENTS

     During fiscal 1999, three clients,  including two  European-based  clients,
accounted  for  approximately  39%  of the  Company's  project  revenues.  These
contracts  are  terminable  by the  Company's  clients  at any  time and for any
reason.  Subsequent  to fiscal  1999,  the  Company  completed  its work on such
projects for the two European  based clients.  Loss of the one U.S.  client or a
reduction  in services  provided to that  client  would have a material  adverse
effect on the Company's business, financial condition and results of operations.




                                      -8-
<PAGE>

EMPLOYEES

     As of September 30, 1999,  the Company had 44 employees,  three of whom are
officers of the Company.

     Of the Company's  employees as of September 30, 1999, eight were engaged in
sales and marketing,  31 were engaged in client  related  projects and five were
engaged in administration and management.  A significant number of the Company's
management  and   professional   employees   have  prior  industry   experience.
Bio-Imaging  believes  that it has been  successful  in  attracting  skilled and
experienced personnel,  however, competition for such personnel is intensifying.
All  of  the   Company's   employees   are   covered  by   confidentiality   and
non-competition  agreements.  The Company  cannot  provide  assurances as to the
enforceability  of such  agreements.  Bio-Imaging has entered into an employment
contract  with one of its  officers.  See  "Item  10.  Executive  Compensation."
Bio-Imaging considers relations with its employees to be good.

ITEM 2.   PROPERTIES.

     On September 22, 1999, the Company executed a lease agreement for
approximately   17,000   square  feet  of  office  space   located  in  Newtown,
Pennsylvania.  The lease is for an initial term of five years and two months and
provides for a fixed base rent of approximately $26,000 per month with an annual
inflation  increase.  The lease for the Company's  current  office space in West
Trenton,  New Jersey  expired on  November  30,  1999 and was not renewed by the
Company.  The Company will occupy it's current office through December 1999. The
Company also leases  approximately  4,000 square feet of office space in Leiden,
the  Netherlands.  This  lease,  denominated  in  Netherland  guilders,  expires
February 14, 2003 and provides for a base rent of approximately $7,200 per month
with an annual  inflation  increase.  The Company believes that these facilities
will be adequate for its needs for the foreseeable future.

ITEM 3.   LEGAL PROCEEDINGS.

     The Company is not a party to any material legal proceedings.

ITEM 4.   SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS.

     None.



                                      -9-
<PAGE>

                                     PART II


ITEM 5.   MARKET FOR THE COMPANY'S COMMON EQUITY AND RELATED STOCKHOLDER
          MATTERS.

     From June 18, 1992  through  March 4, 1999,  the  Company's  common  stock,
$0.00025 par value,  (the "Common Stock") had been traded on the Nasdaq SmallCap
Market  under the symbol  BITI.  On March 4, 1999,  the  Company's  Common Stock
ceased to be listed on the Nasdaq  SmallCap Market and became listed on the NASD
OTC Bulletin Board under the symbol BITI.

     The following  table sets forth the high ask and low bid quotations for the
Common Stock as reported on the Nasdaq  SmallCap Market for each of the quarters
ended  December 31, 1997 through  December 31, 1998 and the high ask and low bid
quotations  as reported on the NASD OTC Bulletin  Board for each of the quarters
ended March 31,  1999  through  September  30,  1999.  Such  quotations  reflect
interdealer prices, without retail mark-up,  mark-down or commission and may not
represent actual transactions.

               Quarter                           Common
                Ended                             Stock
                -----                             -----
                                           High           Low
                                           ----           ---

          December 31, 1997                1.844          0.50
          March 31, 1998                   0.781          0.531
          June 30, 1998                    1.938          0.50
          September 30, 1998               1.00           0.438
          December 31, 1998                0.9375         0.2813
          March 31, 1999                   0.6563         0.3125
          June 30, 1999                    0.6875         0.3125
          September 30, 1999               0.5938         0.2813




                                      -10-
<PAGE>

     Since June 18,  1992,  the Common  Stock also has been listed on the Boston
Stock Exchange ("BSE") under the symbol BIT.

     The following  table sets forth the high ask and low bid quotations for the
Common  Stock as reported on the BSE for each of the  quarters  from the quarter
ended December 31, 1997 through September 30, 1999.


               Quarter                           Common
                Ended                             Stock
                -----                             -----
                                            High           Low
                                            ----           ---

          December 31, 1997                 1.719          0.3125
          March 31, 1998                    0.75           0.375
          June 30, 1998                     1.625          0.375
          September 30, 1998                1.00           0.375
          December 31, 1998                 0.875          0.4375
          March 31, 1999                    0.625          0.4688
          June 30, 1999                     0.875          0.5625
          September 30, 1999                0.781          0.4375


     As of November 30, 1999, the approximate number of holders of record of the
Common Stock was 112 and the  approximate  number of  beneficial  holders of the
Common Stock was 1389.

     The Company has 416,667 shares of Series A Preferred  Stock (the "Preferred
Stock")  outstanding.  The Preferred  Stock provides for (i) voting rights on an
as-converted to Common Stock basis, with standard protective provisions;  (ii) a
liquidation  preference of $1.20 per share; (iii)  anti-dilution  protection and
price protection  provisions;  (iv) cumulative dividends of $0.096 per share per
annum,  payable out of funds legally  available for the payment of dividends and
only upon declaration of dividends by the Board of Directors of the Company; and
(v) registration rights with respect to the shares of Common Stock issuable upon
conversion  of the  Preferred  Stock.  Dividends  are  payable in cash or in the
Company's Common Stock at the Company's discretion.

     The Company has neither  paid nor  declared  dividends  on its Common Stock
since its  inception  and does not plan to pay  dividends on its Common Stock in
the foreseeable  future. The Company expects that any earnings which the Company
may realize and which are not paid as dividends  to holders of  Preferred  Stock
will be retained to finance the growth of the Company.


                                      -11-
<PAGE>

ITEM 6.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
         OF OPERATIONS.

OVERVIEW

     Bio-Imaging is a pharmaceutical  contract service  organization,  providing
services  that support the product  development  process of the  pharmaceutical,
biotechnology  and  medical  device  industries.   The  Company  specializes  in
assisting  its  clients  in the  design and  management  of the  medical-imaging
component  of  clinical  trials for all  modalities  which  consist of CT,  MRI,
x-rays,  DEXA, PET SPECT and  ultrasound.  The Company  provides  services which
include the processing and analysis of medical  images and the  data-basing  and
regulatory submission of medical images, quantitative data and text.

     The Company's sales cycle (the period from the  presentation by the Company
to a  potential  client to the  engagement  of the  Company  by such  client) is
generally twelve months.  In addition,  the contracts under which the Company is
engaged to perform services  typically cover a period of 12 to 36 months and the
volume and type of services  performed by the Company  generally vary during the
course of a project.  In an effort to expand its client base,  obtain additional
contracts and generate additional revenues,  the Company increased its sales and
marketing  efforts  during  the fiscal  year ended  September  30,  1998.  As of
September  30, 1999,  the Company  believes  that these efforts are beginning to
yield  positive  results.  No assurance can be made that the  Company's  project
revenues will increase to levels required to achieve profitability. Although the
Company experienced a loss for 1999, the Company's project revenues increased as
compared to 1998.  Project revenues were generated from 34 clients  encompassing
67  projects  for 1999 as compared to 25 clients  encompassing  46 projects  for
1998. Three clients represented  approximately 16%, 13% and 11% of the Company's
project revenues for 1999. Two clients represented  approximately 26% and 24% of
the Company's project revenues for 1998.

     The Company  believes  that demand for its services and  technologies  will
grow  during  the  longer  term  as the use of  digital  technologies  for  data
acquisition  and  management  increases in the  radiology  and drug  development
communities.  The  Company  also  believes  that there is a growing  recognition
within  the  bio-pharmaceutical  industry  regarding  the use of an  independent
centralized core laboratory for analysis of medical imaging data that is derived
from clinical trials and the rigorous  regulatory  requirements  relating to the
submission  of this  data.  In  addition,  the FDA is  gaining  experience  with
electronic  submissions and is continuing to develop guidelines for computerized
submission of data, including medical images. Furthermore,  the increased use of
digital medical images in clinical trials, especially for important drug classes
such as anti-inflammatory,  neurologic and oncologic therapeutics and diagnostic
image agents, generate large amounts of image data that will require processing,
analysis,  data  management and  submission  services.  Due to several  factors,
including,  without  limitation,  an  increase in  competition,  there can be no
assurance  that demand for the Company's  services and  technologies  will grow,
sustain growth,  or that additional  revenue  generating  opportunities  will be
realized by the Company.



                                      -12-
<PAGE>

     Certain  matters  discussed  in  this  Form  10-KSB  are   "forward-looking
statements" intended to qualify for the safe harbors from liability  established
by the Private  Securities  Litigation  Reform Act of 1995. In  particular,  the
Company's  statements  regarding  the  demand  for the  Company's  services  and
technologies,  growing  recognition for the use of independent  centralized core
laboratories,  trends  toward the  outsourcing  of imaging  services in clinical
trials,  realized return from the Company's  marketing efforts and increased use
of  digital   medical   images  in   clinical   trials  are   examples  of  such
forward-looking  statements.  The  forward-looking  statements include risks and
uncertainties,  including, but not limited to, the timing of revenues due to the
variability in size, scope and duration of projects, regulatory delays, clinical
study results which lead to reductions or cancellations  of projects,  and other
factors, including general economic conditions and regulatory developments,  not
within the Company's  control.  The factors  discussed herein and expressed from
time  to  time  in the  Company's  filings  with  the  Securities  and  Exchange
Commission  could  cause  actual  results  and  developments  to  be  materially
different  from  those  expressed  in  or  implied  by  such   statements.   The
forward-looking  statements  are made only as of the date of this filing and the
Company  undertakes  no  obligation  to  publicly  update  such  forward-looking
statements to reflect subsequent events or circumstances.

RESULTS OF OPERATIONS

     Fiscal Years Ended September 30, 1999 and 1998
     ----------------------------------------------

     Project  revenues  for 1999  and 1998  were  approximately  $4,349,000  and
$3,599,000,  respectively,  an increase of approximately $750,000, or 20.8%. The
increase in project revenues is primarily a result of the increase in the number
of clients and projects  for which the Company was engaged to perform  services.
This increase  resulted  primarily from the increase in the Company's  sales and
marketing  efforts  over  the past  year.  The  Company's  scope of work in both
periods  included  medical  imaging core  laboratory  services  and  image-based
information   management  services.  In  May  1999,  the  Company  acquired  the
operations  of Bona  Fide  in a  transaction  accounted  for as a  purchase.  In
addition to the amount paid at closing of $2,535,  additional  payments  for the
acquisition  may be made  based  on  certain  revenues  being  achieved  for the
twelve-month  period ending on the first  anniversary of the closing date.  Such
amount may not exceed $50,000. The acquisition was not material to the Company's
consolidated  financial  position or results of operations.  The  acquisition of
Bona Fide in May 1999 subsequently contributed approximately $143,000 in project
revenues in 1999.

     Cost of revenues for 1999 and 1998 were comprised of professional  salaries
and  benefits  and  allocated  overhead.  Cost of  revenues  were  approximately
$2,661,000  for 1999 and  approximately  $2,026,000  for 1998,  an  increase  of
approximately  $635,000, or 31.3%. This increase is primarily attributable to an
increase in staffing  levels  required  for  project  related  tasks for 1999 as
compared to 1998.

     The difference  between project revenues and cost of revenues may fluctuate
as a percentage to project  revenues  based on the  utilization of staff and the
mix of services  provided by the  Company to its clients  during the  comparable
periods.  The decrease in this  difference in 1999 from 1998 resulted  primarily
from an increase in staffing  levels in 1999 to support the



                                      -13-
<PAGE>

Company's  existing  contracts and in anticipation of future business along with
the mix of services provided by the Company in 1999 as compared to 1998.

     General and administrative  expenses for 1999 and 1998 consisted  primarily
of  professional   salaries  and  benefits,   depreciation   and   amortization,
professional  and  consulting  services,  office rent and  corporate  insurance.
General and administrative  expenses were approximately  $1,199,000 for 1999 and
approximately  $1,531,000  for 1998.  The  decrease for 1999,  of  approximately
$332,000,  or 21.7%,  from 1998,  resulted  primarily  from the  elimination  of
expenditures in support of the former Marketing  Information  Services  Division
(the "MISD") and Data Management and Information  Systems Division (the "DMISD")
and personnel costs  associated with former  executive  officers who resigned in
December 1997. Such personnel costs were  independent of the  expenditures  that
supported  the former MISD and DMISD  divisions.  This  decrease was offset,  in
part, by personnel costs  associated with the appointment of a new President and
Chief Executive Officer in December 1997.

     Sales and  marketing  expenses  for 1999 and 1998 were  comprised of direct
sales and  marketing  costs,  professional  salaries and benefits and  allocated
overhead.  Sales and marketing expenses were approximately $974,000 for 1999 and
approximately  $1,004,000  for 1998.  The  decrease for 1999,  of  approximately
$30,000,  or 3.0%, from 1998,  resulted primarily from the decrease in personnel
costs  incurred in the three months ended December 30, 1997 which was associated
with the  promotion of the Senior Vice  President of Sales and  Marketing to the
position of President and Chief  Executive  Officer,  which occurred in December
1997. These personnel costs are reflected in general and administrative expenses
in 1999.

     Research  and   development   expenses  for  1999  and  1998  consisted  of
professional  salaries  and  benefits  and  overhead  charged  to  research  and
development  projects.  Research and  development  expenses  were  approximately
$229,000 during 1999 and  approximately  $255,000 for 1998. The decrease in 1999
of  approximately  $26,000,  or 10.2%,  from  1998,  resulted  primarily  from a
decrease in resources dedicated to research and development  projects.  Research
and development  expenses in 1999 and 1998 primarily focused on the formulation,
design and testing of product and process alternatives.

     In 1998,  the  Company  recorded  non-recurring  charges  of  approximately
$597,000  consisting of (i) costs of  approximately  $320,000  associated with a
proxy  contest and  related  litigation  and (ii)  restructuring  and  severance
expenses of $277,000 related to the elimination of two former business divisions
and the resignation in December 1997 of a former executive officer.

     In February  1998,  the Company and a shareholder  group engaged in a proxy
contest in an effort to,  among other  things,  elect  members of the  Company's
Board of Directors at the Annual  Meeting of  Stockholders  held on February 27,
1998. In  connection  with such proxy  contest and the related  litigation,  the
Company expended approximately $320,000 in 1998.

     In 1998,  the Company  recorded  restructuring  and  severance  expenses of
$277,000.  This amount  consisted  of  restructuring  expenses  of $105,000  and
severance expenses of $172,000.


                                      -14-
<PAGE>

     In December 1997, the Company terminated two business  divisions,  the MISD
and the DMISD,  which were  established in October 1996. These divisions did not
meet the Company's expectations and the Company believed that its resources were
better  focused  on its core  clinical  trials  service  business.  The  Company
incurred  restructuring charges of approximately $105,000 which consisted of (i)
$38,000 of severance  costs paid to the former Senior Vice President and General
Manager  of the MISD and (ii)  $67,000  related to the  write-off  of assets and
costs  associated  with the  termination  of the MISD and  DMISD.  Each of these
charges has been reflected in non-recurring charges for 1998.

     In a separate  matter,  two executive  officers of the Company  resigned in
December  1997.  The Company  entered into a separation  agreement with one such
former  executive  officer.  The  Company  agreed to pay such  former  executive
officer  $127,000 in connection  with the separation  agreement.  As a result of
these  resignations,  the Company recorded  severance  expenses of approximately
$172,000. Such expenses have been reflected in non-recurring charges for 1998.

     Total costs and expenses  during 1999 and 1998 consisted  primarily of cost
of revenues,  general and administrative  expenses, sales and marketing expenses
and research and  development  expenses.  The  Company's  cost and expenses were
approximately $5,063,000 in 1999 and $4,816,000 (excluding non-recurring charges
of $597,000) in 1998.  Such  increase of  approximately  $247,000,  or 5.1%,  is
primarily  attributable  to an increase in staffing  levels for project  related
tasks offset by the  elimination of  expenditures  in support of the former MISD
and DMISD  divisions  and  personnel  costs  associated  with  former  executive
officers who resigned in December 1997. Such personnel costs were independent of
the expenditures that supported the former MISD and DMISD divisions.

     Net interest  income of  approximately  $9,000  during 1999  resulted  from
interest earned on cash balances offset in part by interest  expense incurred in
conjunction  with equipment  lease  obligations  and notes payable.  The Company
earned  less  interest  income in 1999 than in 1998 due to lower  cash  balances
maintained during 1999. Net interest income was approximately $88,000 in 1998.

     The  Company's  net  loss for 1999 was  approximately  $705,000  while  the
Company had net loss of  approximately  $1,726,000  for 1998.  The Company's net
loss for 1999 was  attributable  primarily to  insufficient  project  revenue to
support the infrastructure of the Company.

LIQUIDITY AND CAPITAL RESOURCES

     At  September  30,  1999,  the  Company  had cash and cash  equivalents  of
approximately $413,000.  Working capital at September 30, 1999 was approximately
$788,000.

     Net cash used in operating activities for 1999 was approximately  $981,000.
Such use of cash  reflects  the net loss for 1999 and  changes in certain of the
Company's  operating assets and liabilities.  Accounts  receivable  increased by
approximately  $611,000  during  1999  primarily  as a result of an  increase in
unbilled  receivables during such period.  Unbilled  receivables are recorded as
revenue  recognized  to date that has not been billed.  Certain  amounts  become
billable upon the achievement of milestones or in accordance with  predetermined
payment schedules.


                                      -15-
<PAGE>

     For the year ended September 30, 1999, the Company  invested  approximately
$166,000  in  capital  and  leasehold   improvements.   The  Company   currently
anticipates that capital  expenditures for the next fiscal year will approximate
$200,000.  These  expenditures  represent  additional  upgrades in the Company's
networking,  data storage and core  laboratory  capabilities  along with similar
capital requirements for its European operations.

     In December 1998, the Company paid to the holders of its Preferred Stock an
aggregate  amount  of  $20,000,  which  amount  represented  accrued  cumulative
dividends  for the period from July 1, 1998 through and  including  December 31,
1998. In June 1999,  the Company paid to the holders of its  Preferred  Stock an
aggregate  amount  of  $20,000,  which  amount  represented  accrued  cumulative
dividends  for the period from  January 1, 1999 through and  including  June 30,
1999.

     In 1999, the Company  received  aggregate  financing of $145,924 secured by
certain equipment. The loans are payable in 36 monthly installments,  commencing
April 1999 and July 1999, including interest of 10.24% and 10.61%, respectively.

     In August 1999,  the Company  entered  into an agreement  with a bank for a
revolving line of credit of up to $500,000 collaterized by the Company's assets.
Interest  is  payable  at 1.50% over the  bank's  prime  rate of  interest.  The
agreement  requires the Company,  among other things, to maintain minimum levels
of tangible net worth and certain  minimum  financial  ratios.  At September 30,
1999,  the  Company  had no  borrowings  under  the  line of  credit  and was in
compliance  with the  covenants  of the  agreement.  In October  1999,  the bank
notified the Company that it would not make any advances under the existing line
of credit until the Company  provides  sufficient  evidence  satisfactory to the
bank of an  improvement  in the  Company's  operating,  financial  and liquidity
position.  At such  time,  the bank may  consider  permitting  further  advances
pursuant to the loan  agreement.  In December 1999, the Company  entered into an
accounts receivable purchase agreement with the same bank, whereby,  the Company
may assign up to $500,000 of eligible accounts receivable to the bank. The bank,
in turn, would advance the Company up to 80% of the assigned accounts receivable
amount.  Upon  collection  by the bank,  the  balance of the  assigned  accounts
receivable  would be remitted to the Company net of the bank's  finance  charges
and administration fees.

     Also,  in  December  1999,  the Company  entered  into an  equipment  lease
obligation consisting of monthly installments of $4,961, which includes interest
at a rate of 10.53%,  through November 2002. The debt is  collateralized  by the
related equipment.

     The Company  anticipates that its cash and cash equivalents as at September
30, 1999, together with anticipated cash from operations,  will be sufficient to
fund current  working  capital needs and capital  requirements  for at least the
next twelve  months.  There can be no  assurance,  however,  that the  Company's
operating  results  will  achieve  profitability  on an annual basis in the near
future.  The continuation of operating losses, the Company's ability to gain new
client  contracts,  the  variability  of the  timing of  milestone  payments  on
existing client  contracts and other changes in the Company's  operating  assets
and  liabilities  may have a material  adverse  affect on the  Company's  future
liquidity.  In connection  therewith,  the Company may need to raise  additional
capital  in the  foreseeable  future  from  equity or debt  sources  in order to

                                      -16-
<PAGE>

implement  its  business,   sales  or  marketing   plans,   take   advantage  of
unanticipated  opportunities  (such as more  rapid  expansion,  acquisitions  of
complementary  businesses  or the  development  of new  services),  to  react to
unforeseen  difficulties  (such as the decrease in the demand for the  Company's
services  or the  timing of  revenues  due to a variety  of  factors  previously
discussed) or to otherwise respond to unanticipated competitive pressures. There
can be no assurance that additional  financing will be available,  if at all, on
terms acceptable to the Company.

     The Company's 2000 operating plan contains  assumptions  regarding  revenue
and  expenses.  The  achievement  of the operating  plan depends  heavily on the
timing of work performed by the Company on existing  projects and the ability of
the Company to gain and perform  work on new  projects.  Delays in the timing of
work  performed  by the Company on existing  projects  or the  inability  of the
Company to gain and perform work on new projects could have an adverse impact on
the Company's  ability to execute its operating plan and maintain  adequate cash
flow.  In the event actual  results do not meet the operating  plan,  management
believes it could execute contingency plans to mitigate such effects. Such plans
include  additional  financing,  to the extent available,  through the revolving
line of credit agreement and accounts  receivable  purchase agreement  discussed
above.  In addition,  in December 1999, the members of the Board of Directors of
the Company, in their individual capacities, committed up to an aggregate amount
totaling $100,000 in the form of a short-term loan,  through October 1, 2000, if
needed by the Company. Considering the cash on hand and based on the achievement
of the  operating  plan and  management's  actions  taken  to  date,  management
believes it has the ability to continue to generate  sufficient  cash to satisfy
its  operating  requirements  in the  normal  course of  business.  However,  no
assurance can be given that sufficient  cash will be generated from  operations.
As of November 30, 1999, the Company's cash balance was approximately $357,000.

NEW ACCOUNTING REQUIREMENTS

     In  March  1998,  the  Accounting   Standards  Executive  Committee  issued
Statement of Position (SOP 98-1), "Accounting for the Costs of Computer Software
Developed  or  Obtained  for  Internal  Use." SOP 98-1  requires  that  computer
software costs that are incurred in the preliminary project stage be expensed as
incurred and that criteria be met before  capitalization  of costs to develop or
obtain computer  software for internal use. Adoption of SOP 98-1 is required for
fiscal years  beginning  after  December 15, 1998.  The Company does not believe
that the new standard will have a material impact on the Company's  consolidated
financial  statements.   In  April  1998,  the  Accounting  Standards  Executive
Committee issued SOP 98-5,  "Reporting on the Costs of Start-Up Activities." SOP
98-5  requires all costs  incurred as start-up  costs or  organization  costs be
expensed  as  incurred.  Adoption  of SOP  98-5 is  required  for  fiscal  years
beginning  after  December 15,  1998.  The Company does not believe that the new
standard  will have a material  impact on the Company's  consolidated  financial
statements.

EXISTING CONTRACTS

     During  fiscal 1999,  the Company  signed  approximately  $6,564,000 in new
project  contracts.  As of  September  30,  1999,  the Company had entered  into
agreements  with 24 companies  to provide  services in the  aggregate  amount of
approximately  $11,853,000  through  December 2004, of which services  valued at
approximately  $7,054,000 remain to be completed.



                                      -17-
<PAGE>

Such  contracts are subject to  termination by the Company or its clients at any
time or for any reason. In addition,  client's clinical trials or other projects
are subject to timing and scope changes.  Therefore, future revenue generated by
the Company may not equal initial contract values.

EUROPEAN MONETARY UNION

     On January 1, 1999,  eleven of the fifteen member countries of the European
Union set fixed  conversion  rates between their existing legacy  currencies and
the euro. As such, these  participating  countries have agreed to adopt the euro
as their common legal currency.  The eleven  participating  countries will issue
sovereign debt exclusively in euro and will redenominate  outstanding  sovereign
debt.  The legal  currencies  will  continue to be used as legal tender  through
January 1, 2002, at which point the legacy  currencies will be canceled and euro
bills  and  coins  will be  used  for  cash  transactions  in the  participating
countries.  There can be no assurance,  however,  that such euro conversion will
not adversely affect the Company's  business,  financial  condition,  results of
operations or cash flows.

YEAR 2000 COMPLIANCE

     The "Year 2000"  issue  concerns  the  potential  exposures  related to the
automated generation of business and financial misinformation resulting from the
application  of  computer  programs  which have been  written  using two digits,
rather than four, to define the applicable  year of business  transactions.  The
Company has completed its review of the potential impact of Year 2000 issues and
does not anticipate any significant costs, problems or uncertainties  associated
with potential issues relating to Year 2000 compliance.

     The Company's  management  information  systems department has reviewed and
tested the Company's internal business systems,  including operating systems and
internal software, for Year 2000 compliance. The Company believes that, based on
the results of such review and testing, the Company's internal business systems,
including its computer systems, are Year 2000 compliant.

     The supplier of the Company's current financial and accounting software has
informed the Company that such  software is Year 2000  compliant.  Further,  the
Company relies upon various vendors, financial institutions,  utility companies,
telecommunications  service  companies,  delivery  service  companies  and other
service  providers who are outside of the Company's  control.  While the Company
has surveyed all of its major  vendors,  and all of the Company's  major vendors
represented  that they are Year 2000 compliant,  there is no assurance that such
parties  will not suffer a Year 2000  business  disruption,  which  could have a
material  adverse  effect on the  Company's  financial  condition and results of
operations.

     To  date,  the  Company  has not  incurred  any  material  expenditures  in
connection with identifying or evaluating Year 2000 compliance  issues.  Most of
its expenses have related to the opportunity  cost of time spent by employees of
the Company evaluating its systems and Year 2000 compliance matters generally.


                                      -18-
<PAGE>

     The Company has not  developed a Year  2000-specific  contingency  plan. If
Year 2000 compliance  issues are discovered,  the Company then will evaluate the
need for contingency plans relating to such issues.

     The  Year  2000   disclosures   discussed   above  are  based  on  numerous
expectations  which are subject to  uncertainties.  Certain risk  factors  which
could have a material adverse effect on the Company's  results of operations and
financial condition include but are not limited to: failure to identify critical
systems  which will  experience  failures,  errors in the  remediation  efforts,
inability to obtain new  replacements  for  non-compliant  systems or equipment,
general  economic  downturn  relating to Year 2000  failures in the U.S.  and in
other  countries,  failures in global banking  systems and capital  markets,  or
extended  failures by public and private  utility  companies or common  carriers
supplying services to the Company.

ITEM 7.   FINANCIAL STATEMENTS.

     The financial  statements  required to be filed pursuant to this Item 7 are
included  in  this  Annual  Report  on  Form  10-KSB.  A list  of the  financial
statements filed herewith is found at "Item 13.  Exhibits,  List, and Reports on
Form 8-K."

ITEM 8.   CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND
          FINANCIAL DISCLOSURE.

     On January 12, 1998,  the Company  selected  Arthur  Andersen LLP to act as
independent  accountants  for the  Company  and  informed  the  prior  auditors,
Goldstein,  Golub, Kessler & Compnay,  P.C., of its decision. In connection with
its audits for each of the two years in the period ended  September 30, 1997 and
thereafter,  there were no disagreements  with the prior auditors on any matters
of accounting  principles  or  practices,  financial  statement  disclosure,  or
auditing  scope or  procedures.  The prior  auditor's  report  on the  Company's
financial statements for each of the two years in the period ended September 30,
1997 contained no adverse  opinion or disclaimer of opinion and was not modified
or qualified as to  uncertainty,  audit scope,  or  accounting  principles.  The
decision to change  accountants  was  approved by the Board of  Directors of the
Company.  The prior auditors have furnished the Company with a letter  addressed
to the Securities and Exchange Commission stating their agreement with the above
statements.





                                      -19-
<PAGE>

                                    PART III


ITEM 9.   DIRECTORS, EXECUTIVE OFFICERS, PROMOTERS AND CONTROL PERSONS;
          COMPLIANCE WITH SECTION 16(A) OF THE EXCHANGE ACT.

     The information relating to the Company's directors,  nominees for election
as directors and executive  officers under the headings  "Election of Directors"
and "Executive  Officers" in the Company's  definitive  proxy  statement for the
2000 Annual Meeting of Stockholders is incorporated  herein by reference to such
proxy statement.

ITEM 10.  EXECUTIVE COMPENSATION.

     The discussion under the heading "Executive  Compensation" in the Company's
definitive  proxy  statement  for the 2000  Annual  Meeting of  Stockholders  is
incorporated herein by reference to such proxy statement.

ITEM 11.  SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT.

     The discussion under the heading "Security  Ownership of Certain Beneficial
Owners and Management" in the Company's  definitive proxy statement for the 2000
Annual Meeting of Stockholders is incorporated herein by reference to such proxy
statement.

ITEM 12.  CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS.

     The  discussion  under  the  heading  "Certain  Relationships  and  Related
Transactions"  in the Company's  definitive  proxy statement for the 2000 Annual
Meeting  of  Stockholders  is  incorporated  herein by  reference  to such proxy
statement.

ITEM 13.  EXHIBITS, LIST, AND REPORTS ON FORM 8-K.

     (a)  (1)  Financial Statements.

          Reference  is made to the Index to Financial  Statements  on Page F-1.

     (a)  (2)  Financial Statement Schedules.

          None.

     (a)  (3)  Exhibits.

          Reference is made to the Index to Exhibits on Page 23.

     (b)       Reports on Form 8-K.

          None.



                                      -20-
<PAGE>

                                   SIGNATURES

     Pursuant  to the  requirements  of  Section  13 or 15(d) of the  Securities
Exchange Act of 1934, the Registrant has duly caused this report to be signed on
its  behalf  by the  undersigned,  thereunto  duly  authorized  this 29th day of
December, 1999.

                                         BIO-IMAGING TECHNOLOGIES, INC.



                                         By: /s/Mark L. Weinstein
                                             ----------------------------------
                                         Mark L. Weinstein, President and Chief
                                         Executive Officer



                                      -21-
<PAGE>


     Pursuant to the  requirements of the Securities  Exchange Act of 1934, this
report  has  been  signed  below  by the  following  persons  on  behalf  of the
Registrant and in the capacities and on the dates indicated.


SIGNATURE                    TITLE                             DATE
- ---------                    -----                             ----


/s/Mark L. Weinstein         President and Chief               December 29, 1999
- -------------------------
Mark L. Weinstein            Executive Officer and Director
                             (principal executive
                             officer)

/s/Robert J. Phillips        Vice President and Chief          December 29, 1999
- -------------------------
Robert J. Phillips           Financial Officer
                             (principal financial and
                             accounting officer)

/s/Jeffrey H. Berg, Ph.D.    Director                          December 29, 1999
- -------------------------
Jeffrey H. Berg, Ph.D.


/s/Marc Berger               Director                          December 29, 1999
- -------------------------
Marc Berger


/s/David E. Nowicki, DMD     Director                          December 29, 1999
- -------------------------
David E. Nowicki, DMD


/s/James A. Taylor, Ph.D.    Director                          December 29, 1999
- -------------------------
James A. Taylor, Ph.D.


                                      -22-
<PAGE>

                                  EXHIBIT INDEX

Exhibit
  No.                             Description of Exhibit
- -------                           ----------------------

3.1       Restated Certificate of Incorporation of the Company. (Incorporated by
          reference to Exhibit 3.1 to the  Company's  Registration  Statement on
          Form S-1 (File Number  33-47471)  which  became  effective on June 18,
          1992.)  (Amendments  incorporated  by  reference to Exhibit 3.1 to the
          Company's  Annual Report on Form 10-K for the year ended September 30,
          1993 and to  Exhibit  3.1 to the  Company's  Quarterly  Report on Form
          10-QSB for the quarter ended March 31, 1995.)

3.2       By-Laws of the Company.  (Incorporated  by reference to Exhibit 3.2 to
          the  Company's   Registration  Statement  on  Form  S-1  (File  Number
          33-47471) which became effective on June 18, 1992.)

4.1       Specimen  Common  Stock  Certificate.  (Incorporated  by  reference to
          Exhibit 4.1 to the Company's  Registration Statement on Form S-1 (File
          Number 33-47471) which became effective on June 18, 1992.)

4.2       Registration  Agreement dated October 13, 1994 between the Company and
          Corning Pharmaceuticals  Services Inc., now Covance, Inc. ("Covance").
          (Incorporated  by  reference to Exhibit 4.1 to the  Company's  Current
          Report on Form 8-K dated October 13, 1994.)

4.3       Purchase  Agreement  for  Units of  Convertible  Preferred  Stock  and
          Warrants  dated  December  8,  1995  between  Investment  Partners  of
          America,  L.P.,  as  Purchaser,  and the Company,  including  material
          exhibits (including the Certificate of Designation for the Convertible
          Preferred  Stock).  (Incorporated  by  reference to Exhibit 4.1 to the
          Company's Current Report on Form 8-K dated December 22, 1995.)

10.1      Lease between Mountain View Office Park and the Company. (Incorporated
          by  reference  to  (i)  Exhibit  10.1  to the  Company's  Registration
          Statement on Form S-1 (File Number 33-47471) which became effective on
          June 18, 1992,  (ii) Exhibit 10.1 to the  Company's  Annual  Report on
          Form 10-K for the fiscal year ended September 30, 1992,  (iii) Exhibit
          10.1 to the Company's Annual Report on Form 10-KSB for the fiscal year
          ended  September 30, 1994,  (iv) Exhibit 10.1 to the Company's  Annual
          Report on Form 10-KSB for the fiscal year ended  September  30, 1995),
          as amended effective  September 5, 1996  (Incorporated by Reference to
          Exhibit  10.1 to the  Company's  Annual  Report on Form 10-KSB for the
          fiscal year ended  September 30, 1996) (v) as amended  effective  June
          22, 1998  (Incorporated  by Reference to Exhibit 10.1 to the Company's
          Annual  Report on Form 10-KSB for the fiscal year ended  September 30,
          1998).



                                      -23-
<PAGE>

Exhibit
  No.                             Description of Exhibit
- -------                           ----------------------

10.2*     1991 Stock Option Plan.  (Incorporated by reference to Exhibit 10.6 to
          the  Company's   Registration  Statement  on  Form  S-1  (File  Number
          33-47471) which became effective on June 18, 1992.)

10.3*     401(k)  Plan.  (Incorporated  by  reference  to  Exhibit  10.7  to the
          Company's  Registration  Statement on Form S-1 (File Number  33-47471)
          which became effective on June 18, 1992.)

10.4      Form of Employee's Invention Assignment,  Confidential Information and
          Non-Competition Agreement.  (Incorporated by reference to Exhibit 10.9
          to the Company's  Annual Report on Form 10-K for the fiscal year ended
          September 30, 1992.)

10.5      Stock  Purchase  Agreement  dated October 13, 1994 between the Company
          and  Covance.  (Incorporated  by  reference  to  Exhibit  10.2  to the
          Company's Current Report on Form 8-K dated October 13, 1994.)

10.6      Master Lease Agreement dated April 25, 1994 by and between the Company
          and Wasco  Funding Corp.  and schedules  thereto dated May 9, 1995 and
          August 31, 1995.  (Incorporated  by reference to Exhibit  10.24 to the
          Company's  Annual  Report on Form  10-KSB  for the  fiscal  year ended
          September 30, 1995.)

10.7*     Employment  Agreement including Invention  Assignment and Confidential
          Information Agreement dated April 15, 1998, by and between the Company
          and Mark L. Weinstein.  (Incorporated  by reference to Exhibit 10.1 to
          the  Company's  Quarterly  Report on Form 10-QSB for the quarter ended
          June 30, 1998.)

10.8      Purchase  Agreement  for  Units of  Convertible  Preferred  Stock  and
          Warrants  dated  December  8,  1995  between  Investment  Partners  of
          America,  L.P.,  as  Purchaser  and the  Company,  including  material
          exhibits.  (Incorporated  by reference to Exhibit 4.1 to the Company's
          Current Report on Form 8-K dated December 22, 1995.)

10.9      Office  Space Lease dated  September  22, 1999  between  Yardley  Road
          Associates, L.P. and the Company.

10.10     Revolving Promissory Note and Loan and Security Agreement dated August
          10, 1999 between Silicon Valley Bank and the Company.

10.11     Accounts Receivable Purchase Agreement dated December 22, 1999 between
          Silicon Valley Bank and the Company.

16        Letter  re:  Change  in  Certifying   Accountants.   (Incorporated  by
          reference to Exhibit 16 to the Company's  Annual Report on Form 10-KSB
          for the fiscal year ended September 30, 1998.)

                                      -24-
<PAGE>

Exhibit
  No.                             Description of Exhibit
- -------                           ----------------------

21        List of  Subsidiaries  of  Registrant.  (Incorporated  by reference to
          Exhibit  21.1 to the  Company's  Annual  Report on Form 10-KSB for the
          fiscal year ended September 30, 1997.)

23.1      Consent of Arthur Andersen LLP.

27        Financial Data Schedule for the year ended September 30, 1999.

- ----------------
*       A management contract or compensatory plan or arrangement required to be
        filed as an exhibit pursuant to Item 13(a) of Form 10-KSB.

          (b)  Financial Statement Schedules

               None.


                                      -25-
<PAGE>

                                 Bio-Imaging Technologies, Inc. and Subsidiaries


                                                                       CONTENTS
- --------------------------------------------------------------------------------
Report of Independent Public Accountants                                  F-2

Consolidated Financial Statements:

Balance Sheets                                                            F-3
Statements of Operations                                                  F-4
Statements of Stockholders' Equity                                        F-5
Statements of Cash Flows                                                  F-6
Notes to Consolidated Financial Statements                                F-7






                                      F-1
<PAGE>


                    REPORT OF INDEPENDENT PUBLIC ACCOUNTANTS



To the Board of Directors and Stockholders of
Bio-Imaging Technologies, Inc.:


We have audited the  accompanying  consolidated  balance  sheets of  Bio-Imaging
Technologies, Inc. (a Delaware corporation) and subsidiaries as of September 30,
1999  and  1998,  and  the  related   consolidated   statements  of  operations,
stockholders'  equity and cash flows for the years then ended.  These  financial
statements   are  the   responsibility   of  the   Company's   management.   Our
responsibility  is to express an opinion on these financial  statements based on
our audits.

We  conducted  our  audits  in  accordance  with  generally   accepted  auditing
standards.  Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements are free of material
misstatement.  An audit includes examining, on a test basis, evidence supporting
the amounts and disclosures in the financial statements.  An audit also includes
assessing the  accounting  principles  used and  significant  estimates  made by
management,  as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.

In our opinion,  the financial  statements  referred to above present fairly, in
all material respects, the financial position of Bio-Imaging Technologies,  Inc.
and  subsidiaries  as of September  30, 1999 and 1998,  and the results of their
operations  and their cash flows for the years  then  ended in  conformity  with
generally accepted accounting principles.



                                      /s/Arthur Andersen LLP
                                      ARTHUR ANDERSEN LLP

Roseland, New Jersey
December 22, 1999




                                      F-2
<PAGE>

                                 Bio-Imaging Technologies, Inc. and Subsidiaries

<TABLE>
CONSOLIDATED BALANCE SHEETS
<CAPTION>
SEPTEMBER 30,                                                              1999                1998
- -------------------------------------------------------------------------------------------------------

ASSETS
<S>                                                                    <C>                 <C>
Current Assets:
Cash and cash equivalents                                              $   412,903         $ 1,527,330
Accounts receivable, net of allowance for doubtful
  accounts of $65,000 in 1999 and 1998                                   1,237,746             626,376
Prepaid expenses and other current assets                                  138,127              84,747
- -------------------------------------------------------------------------------------------------------
TOTAL CURRENT ASSETS                                                     1,788,776           2,238,453
Property and equipment, net                                              1,180,254           1,543,434
Other assets                                                               179,624              32,235
- -------------------------------------------------------------------------------------------------------
TOTAL ASSETS                                                           $ 3,148,654         $ 3,814,122
=======================================================================================================

LIABILITIES AND STOCKHOLDERS' EQUITY

Current Liabilities:
Accounts payable                                                       $   134,685         $   142,071
Accrued expenses and other current liabilities                             254,565             261,063
Deferred revenue                                                           541,933             522,605
Current maturities of long-term debt                                        69,800              49,956
- -------------------------------------------------------------------------------------------------------
TOTAL CURRENT LIABILITIES                                                1,000,983             975,695
Long-term debt                                                              81,511              26,808
- -------------------------------------------------------------------------------------------------------
TOTAL LIABILITIES                                                        1,082,494           1,002,503
- -------------------------------------------------------------------------------------------------------
Stockholders' Equity:
Convertible cumulative preferred stock - $.00025 par value;
  authorized 3,000,000 shares, issued and outstanding 416,667 shares
  ($500,000 liquidation preference)                                            104                 104
Common stock - $.00025 par value; authorized 18,000,000 shares,
  issued and outstanding 7,773,878 shares in 1999 and 1998                   1,944               1,944
Additional paid-in capital                                               9,231,497           9,231,497
Accumulated deficit                                                     (7,167,385)         (6,421,926)
- -------------------------------------------------------------------------------------------------------
STOCKHOLDERS' EQUITY                                                     2,066,160           2,811,619
- -------------------------------------------------------------------------------------------------------
TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY                              $3,148,654          $3,814,122
=======================================================================================================
</TABLE>



      The accompanying notes are an integral part of these balance sheets.



                                      F-3
<PAGE>

                                 Bio-Imaging Technologies, Inc. and Subsidiaries

CONSOLIDATED STATEMENTS OF OPERATIONS
<TABLE>
<CAPTION>
YEAR ENDED SEPTEMBER 30,                                                   1999                1998
- -------------------------------------------------------------------------------------------------------
<S>                                                                    <C>                 <C>
Project revenues                                                       $ 4,349,079         $ 3,599,313
- -------------------------------------------------------------------------------------------------------

Cost and expenses:

       Cost of revenues                                                  2,660,659           2,025,868

       General and administrative expenses                               1,199,137           1,531,380

       Sales and marketing expenses                                        974,264           1,003,523

       Research and development expenses                                   229,238             255,321

       Non-recurring charges                                                     -             597,000
- -------------------------------------------------------------------------------------------------------
               Total cost and expenses                                   5,063,298           5,413,092
- -------------------------------------------------------------------------------------------------------

Loss from operations                                                      (714,219)         (1,813,779)

Interest income, net                                                         8,760              88,223
- -------------------------------------------------------------------------------------------------------

Net loss                                                                  (705,459)         (1,725,556)

Dividends on preferred stock                                                40,000              50,285
- -------------------------------------------------------------------------------------------------------

Net loss applicable to common stock                                    $  (745,459)        $(1,775,841)
=======================================================================================================

Basic and diluted loss per common share                                $     (0.10)        $     (0.23)
=======================================================================================================

Weighted average number of common shares and dilutive
common equivalent shares                                                 7,773,878           7,772,230
=======================================================================================================
</TABLE>


        The accompanying notes are an integral part of these statements.




                                      F-4
<PAGE>


                                 Bio-Imaging Technologies, Inc. and Subsidiaries

CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY
<TABLE>
<CAPTION>
                                                                               ADDITIONAL
                                 PREFERRED STOCK         COMMON STOCK           PAID-IN      ACCUMULATED    STOCKHOLDERS'
                               SHARES       AMOUNT    SHARES        AMOUNT      CAPITAL        DEFICIT        EQUITY
- -------------------------------------------------------------------------------------------------------------------------

<S>                           <C>           <C>      <C>           <C>        <C>            <C>             <C>
Balance at
September 30, 1997            416,667       $ 104    7,753,878     $ 1,939    $ 9,215,603    $(4,646,085)    $ 4,571,561

Stock options exercised             -           -       20,000           5         15,894              -          15,899

Dividends on preferred
stock                               -           -            -           -              -        (50,285)        (50,285)

Net loss                            -           -            -           -              -     (1,725,556)     (1,725,556)

- -------------------------------------------------------------------------------------------------------------------------

Balance at
September 30, 1998            416,667         104    7,773,878       1,944      9,231,497     (6,421,926)      2,811,619

Dividends on preferred
stock                               -           -            -           -              -        (40,000)        (40,000)

Net loss                            -           -            -           -              -       (705,459)       (705,459)

- -------------------------------------------------------------------------------------------------------------------------

Balance at
September 30, 1999            416,667       $ 104    7,773,878     $ 1,944    $ 9,231,497    $(7,167,385)    $ 2,066,160
=========================================================================================================================
</TABLE>



               The accompanying notes are an integral part of these statements.




                                      F-5
<PAGE>


                                 Bio-Imaging Technologies, Inc. and Subsidiaries

CONSOLIDATED STATEMENTS OF CASH FLOWS
<TABLE>
<CAPTION>
YEAR ENDED SEPTEMBER 30,                                                   1999                1998
- -------------------------------------------------------------------------------------------------------
<S>                                                                    <C>                 <C>
Cash flows from operating activities:
Net loss                                                               $ (705,459)         $(1,725,556)
Adjustments to reconcile net loss to net cash
used in operating activities:
  Depreciation and amortization                                           551,038              559,301
  Provision for losses on accounts receivable                                   -               45,000
  Write-off of assets                                                           -               52,154
  Changes in operating assets and liabilities, net of assets and
   liabilities acquired in a business combination:
    (Increase) decrease in accounts receivable                           (611,370)             542,676
    Increase in prepaid expenses and other current assets                 (53,380)              (5,977)
    Decrease in other assets                                               20,611               12,435
    (Decrease) increase in accounts payable                                (7,386)              60,239
    (Decrease) increase in accrued expenses and other current
     liabilities                                                          (71,498)              11,711
    (Decrease) increase in deferred revenue                              (103,137)             108,245
- -------------------------------------------------------------------------------------------------------
NET CASH USED IN OPERATING ACTIVITIES                                    (980,581)            (339,772)
- -------------------------------------------------------------------------------------------------------

Cash flows from investing activities:
  Purchases of property and equipment                                    (165,858)            (377,462)
  Cash paid for business acquisition                                       (2,535)                   -
- -------------------------------------------------------------------------------------------------------
NET CASH USED IN INVESTING ACTIVITIES                                    (168,393)            (377,462)
- -------------------------------------------------------------------------------------------------------

Cash flows from financing activities:
  Payments of long term debt                                              (71,377)             (98,708)
  Dividends paid to preferred stockholders                                (40,000)             (40,285)
  Proceeds from long-term debt                                            145,924                    -
  Proceeds from exercise of stock options                                       -               15,899
- -------------------------------------------------------------------------------------------------------
NET CASH PROVIDED BY (USED IN) FINANCING ACTIVITIES                        34,547             (123,094)
- -------------------------------------------------------------------------------------------------------

Net decrease in cash and cash equivalents                              (1,114,427)            (840,328)
Cash and cash equivalents at beginning of year                          1,527,330            2,367,658
=========================================================================================================================
Cash and cash equivalents at end of year                               $  412,903          $ 1,527,330
=========================================================================================================================

SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION:
  Cash paid during the year for interest                               $   12,412          $     3,775
=========================================================================================================================

SUPPLEMENTAL SCHEDULE OF NONCASH INVESTING AND FINANCING ACTIVITIES:
  Equipment purchased under capital lease obligations                  $        -          $    75,595
=========================================================================================================================
</TABLE>

        The accompanying notes are an integral part of these statements.



                                      F-6
<PAGE>

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                                 Bio-Imaging Technologies, Inc. and Subsidiaries

1.  PRINCIPAL BUSINESS ACTIVITY AND SIGNIFICANT ACCOUNTING POLICIES

DESCRIPTION OF BUSINESS AND FUTURE OPERATIONS
Bio-Imaging Technologies, Inc. and Subsidiaries ("Bio-Imaging" or "the Company")
is a  pharmaceutical  contract service  organization,  operating in one business
segment,  providing services that support the product development process of the
pharmaceutical,   biotechnology  and  medical  device  industries.  The  Company
specializes  in  assisting  its  clients  in the design  and  management  of the
medical-imaging component of clinical trials for all modalities which consist of
computerized tomography ("CT"), magnetic resonance imaging ("MRI"), x-rays, dual
energy x-ray absorptiometry ("DEXA"), position emission tomography single photon
emission  computerized  tomography  ("PET  SPECT") and  ultrasound.  The Company
provides  services  which include the  processing and analysis of medical images
and the  data-basing and regulatory  submission of medical images,  quantitative
data and text.

The Company's  2000 operating plan contains  assumptions  regarding  revenue and
expenses. The achievement of the operating plan depends heavily on the timing of
work  performed  by the  Company on  existing  projects  and the  ability of the
Company to gain and perform work on new  projects.  Delays in the timing of work
performed by the Company on existing projects or the inability of the Company to
gain and  perform  work on new  projects  could  have an  adverse  impact on the
Company's ability to execute its operating plan and maintain adequate cash flow.
In the event actual results do not meet the operating plan,  management believes
it could execute contingency plans to mitigate such effects.  Such plans include
additional  financing,  to the extent  available,  through the revolving line of
credit agreement and accounts  receivable purchase  agreement.  In addition,  in
December  1999,  the members of the Board of Directors of the Company,  in their
individual capacities,  committed up to an aggregate amount totaling $100,000 in
the form of a  short-term  loan,  through  October  1,  2000,  if  needed by the
Company.  Considering  the cash on hand  and  based  on the  achievement  of the
operating plan and management's  actions taken to date,  management  believes it
has the ability to continue to generate sufficient cash to satisfy its operating
requirements  in the normal  course of business.  However,  no assurance  can be
given that sufficient cash will be generated from operations. As of November 30,
1999, the Company's cash balance was approximately $357,000.

PRINCIPLES OF CONSOLIDATION
The accompanying  consolidated  financial statements include the accounts of the
Company and its wholly owned subsidiaries, Oxford Bio-Imaging Research, Inc. and
Bio-Imaging Technologies Holding B.V. All significant intercompany  transactions
and balances have been eliminated.

USE OF ESTIMATES
The preparation of financial  statements in conformity  with generally  accepted
accounting principles requires management to make estimates and assumptions that
affect  the  reported  amounts  of assets  and  liabilities  and  disclosure  of
contingent  assets and  liabilities at the date of the financial  statements and
the  reported  amounts of revenues  and expenses  during the  reporting  period.
Actual results could differ from those estimates.



                                      F-7
<PAGE>

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                                 Bio-Imaging Technologies, Inc. and Subsidiaries

CASH AND CASH EQUIVALENTS
The  Company   maintains   substantially  all  of  its  cash  in  one  financial
institution.   The  Company  has  defined  cash  equivalents  as  highly  liquid
investments with an original maturity at the time of purchase of three months or
less.

REVENUE RECOGNITION
Project  revenues are recognized  primarily  using the  percentage-of-completion
method of  accounting  for  services  rendered in  connection  with  contractual
arrangements,  which generally range from a few months to two years.  Provisions
for losses to be incurred on contracts  are  recognized in full in the period in
which  it is  determined  that  a  loss  will  result  from  performance  of the
contractual  arrangement.  Unbilled services are recorded for revenue recognized
to date that is  currently  unbillable  to the client  pursuant  to  contractual
terms.  In general,  amounts become billable upon the achievement of contractual
milestones or in  accordance  with  predetermined  payment  schedules.  Unbilled
services are  generally  billable  within one year from the  respective  balance
sheet date. Accounts receivable include  approximately  $806,000 and $493,000 of
unbilled  receivables  at September  30, 1999 and 1998,  respectively.  Deferred
revenue is recorded for cash  received  from  clients for which  revenue has not
been  recognized  at the  respective  balance  sheet  date.  Revenue  from other
activities is recognized as services are performed.

PROPERTY AND EQUIPMENT
Depreciation  of property and equipment is provided for using the  straight-line
method over the estimated useful lives of the respective assets. Amortization of
leasehold improvements is provided for over the related lease term.

CAPITALIZED SOFTWARE DEVELOPMENT
The  Company   capitalizes   software   development  costs  after  technological
feasibility  has been determined and ceases  capitalization  at such time as the
end product is available for general release to the public. The establishment of
technological  feasibility  and the  ongoing  assessment  of  recoverability  of
capitalized  software   development  costs  require  considerable   judgment  by
management with respect to certain external factors  including,  but not limited
to, anticipated future revenue,  estimated economic life and changes in software
and hardware  technologies.  At September 30, 1999,  management has estimated an
economic  useful  life  of  30  months  and  is  amortizing  these  costs  on  a
straight-line  basis  over this  period.  The  amortization  period is  reviewed
annually  by  management.  During  1999 and 1998,  the  Company  had no costs of
software development that were capitalized.

LONG LIVED  ASSETS
The  Company  continually  reviews  its long lived  assets to  evaluate  whether
changes  have  occurred  to  suggest  whether  or not long  lived  assets may be
impaired based on estimated  undiscounted  cash flows. If this review  indicates
that long lived assets are impaired,  the carrying amounts of these assets would
be reduced based on the estimated shortfall of cash flows on a discounted basis.
Management  does not  believe  that there is any such  impairment  of long lived
assets as of September 30, 1999.



                                      F-8
<PAGE>

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                                 Bio-Imaging Technologies, Inc. and Subsidiaries

BUSINESS ACQUISITION
In May 1999,  the  Company  acquired  the  operations  of Bona Fide,  Ltd.  in a
transaction  accounted for as a purchase.  Tangible assets acquired were $10,000
and liabilities  assumed were approximately  $190,000,  resulting in goodwill of
$180,000.  The  liabilities  assumed  primarily  represent  deferred  revenue of
$122,000  which the Company  expects to recognize as project  revenues  over the
duration  of the  client  contracts  which were  assumed  by the  Company in the
acquisition.  Goodwill is being amortized using a straight-line method over five
years.  In addition to the amount paid at closing,  additional  payments for the
acquisition  may be made  based  on  certain  revenues  being  achieved  for the
twelve-month  period ending on the  anniversary of the closing date. Such amount
may not exceed  $50,000.  The  acquisition  was not  material  to the  Company's
consolidated financial position or results of operations.

FOREIGN CURRENCY TRANSLATION
The  U.S.  Dollar  is  the  functional   currency  for  the  Company's   foreign
subsidiaries.

EARNINGS PER SHARE
The Company  follows SFAS No. 128 - "Earnings per Share. " SFAS No. 128 requires
the  presentation  of basic  earnings per share and diluted  earnings per share.
Basic loss per common share was calculated  based upon the net loss available to
common  stockholders  divided by the weighted average number of shares of common
stock outstanding during the period.  Diluted loss per common share for the year
ended  September 30, 1999 and 1998 excludes the impact of options  (1,192,370 as
of September  30, 1999) and warrants  (66,667 as of September  30, 1999) as they
are antidilutive.

RECENTLY ISSUED ACCOUNTING STANDARDS
In March 1998, the Accounting  Standards Executive Committee issued Statement of
Position (SOP 98-1), "Accounting for the Costs of Computer Software Developed or
Obtained for Internal Use." SOP 98-1 requires that computer  software costs that
are incurred in the  preliminary  project stage be expensed as incurred and that
criteria  be met before  capitalization  of costs to develop or obtain  computer
software  for  internal  use.  Adoption of SOP 98-1 is required for fiscal years
beginning  after  December 15,  1998.  The Company does not believe that the new
standard  will have a material  impact on the Company's  consolidated  financial
statements.  In April 1998, the Accounting  Standards Executive Committee issued
SOP 98-5, "Reporting on the Costs of Start-Up Activities." SOP 98-5 requires all
costs incurred as start-up costs or organization  costs be expensed as incurred.
Adoption of SOP 98-5 is required for fiscal years  beginning  after December 15,
1998.  The Company does not believe  that the new standard  will have a material
impact on the Company's consolidated financial statements.



                                      F-9
<PAGE>

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                                 Bio-Imaging Technologies, Inc. and Subsidiaries

2.  PROPERTY AND EQUIPMENT
<TABLE>
Property and equipment, at cost, consists of the following:
<CAPTION>
                                                                                Estimated
September 30,                                 1999             1998           Useful Life
- ------------------------------------------------------------------------------------------
<S>                                        <C>              <C>                   <C>
Equipment                                  $ 3,496,440      $ 3,340,764           5 years
Equipment under capital leases                 640,914          640,914           5 years
Furniture and fixtures                         266,554          246,371           7 years
Leasehold improvements                          84,060           84,060     Term of lease
Computer software costs                        123,436          123,436         30 months
- ------------------------------------------------------------------------------------------
                                             4,611,404        4,435,545
Less accumulated depreciation
and amortization                            (3,431,150)      (2,892,111)
- ------------------------------------------------------------------------------------------
                                           $ 1,180,254      $ 1,543,434
==========================================================================================
</TABLE>

Accumulated  depreciation  related to equipment  acquired  under capital  leases
amounted to approximately  $537,000 and $465,000 at September 30, 1999 and 1998,
respectively.

Accumulated   amortization  related  to  computer  software  costs  amounted  to
approximately   $123,000  and   $111,000  at   September   30,  1999  and  1998,
respectively.

3.  LONG-TERM DEBT

Long-term debt consists of an equipment lease obligation and notes payable.  The
equipment lease obligation and notes payable are payable in monthly installments
ranging from $1,170 to $3,562, including interest at rates ranging from 9.53% to
10.61%, through June 2002. The debt is collateralized by the related equipment.

Aggregate maturities of long-term debt at September 30, 1999 are as follows:

                 2000                                 $ 69,800
                 2001                                   50,706
                 2002                                   30,805
- --------------------------------------------------------------
                                                      $151,311
==============================================================

In  August  1999,  the  Company  entered  into an  agreement  with a bank  for a
revolving line of credit of up to $500,000 collaterized by the Company's assets.
Interest  is  payable  at 1.50% over the  bank's  prime  rate of  interest.  The
agreement  requires the Company,  among other things, to maintain minimum levels
of tangible net worth and certain  minimum  financial  ratios.  At September 30,
1999 the Company had no



                                      F-10
<PAGE>

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                                 Bio-Imaging Technologies, Inc. and Subsidiaries

borrowings  under the line of credit and was in compliance with the covenants of
the agreement.  In October 1999, the bank notified the Company that it would not
make any advances  under the existing line of credit until the Company  provides
sufficient evidence  satisfactory to the bank of an improvement in the Company's
operating, financial and liquidity position. At such time, the bank may consider
permitting  further advances  pursuant to the loan agreement.  In December 1999,
the Company entered into an accounts receivable purchase agreement with the same
bank,  whereby,  the Company  may assign up to  $500,000  of  eligible  accounts
receivable to the bank.  The bank, in turn,  would advance the Company up to 80%
of the assigned  accounts  receivable  amount.  Upon collection by the bank, the
balance of the assigned accounts receivable would be remitted to the Company net
of the bank's finance charges and administration fees.

In December  1999,  the  Company  entered  into an  equipment  lease  obligation
consisting of monthly  installments of $4,961,  which include interest at a rate
of 10.53%,  through  November  2002. The debt is  collateralized  by the related
equipment.

4.  STOCKHOLDERS' EQUITY

In  December  1991  and  June  1992,  the  Company's   Board  of  Directors  and
stockholders,   respectively,   approved   the   adoption  of  the   Bio-Imaging
Technologies,  Inc.  Stock  Option Plan.  In January 1995 and 1997,  the Company
amended  this plan to provide  for the  granting  of  options to key  employees,
directors and  consultants  to purchase an aggregate of not more than  1,800,000
and 2,400,000 shares,  respectively,  of the Company's common stock. Each option
is exercisable  into one share of common stock.  Options granted pursuant to the
plan,  to be  granted  at prices  not less than fair value at the date of grant,
consist of qualified incentive stock options, as defined in the Internal Revenue
Code, and nonqualified  options. Such stock options have terms not exceeding ten
years and  vesting  terms vary from  immediate  vesting on date of grant to five
years.



                                      F-11
<PAGE>

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                                 Bio-Imaging Technologies, Inc. and Subsidiaries

The following table summarizes the transactions  pursuant to the Company's stock
option plan for the two-year period ended September 30, 1999:

                                             Number of      Weighted Average
                                              Options        Exercise Price
- -----------------------------------------------------------------------------
Unexercised options outstanding at
September 30, 1997                            1,485,000           $ 1.40
Options granted                                 317,250             0.67
Options canceled                               (513,500)            0.93
Options exercised                               (20,000)            0.80
- -----------------------------------------------------------------------------
Unexercised options outstanding at
September 30, 1998                            1,268,750             1.41
Options granted                                 267,620             0.63
Options canceled                               (344,000)            1.05
- -----------------------------------------------------------------------------
Unexercised options outstanding at
September 30, 1999                            1,192,370           $ 1.34
=============================================================================

Approximately  765,000 and 882,000 options are exercisable at September 30, 1999
and 1998, respectively, at a weighted average exercise price of $1.66 and $1.62,
respectively.

The Company has elected,  in  accordance  with the  provisions  of SFAS No. 123,
Accounting for  Stock-Based  Compensation  ("SFAS 123"), to apply the accounting
rules under APB Opinion No. 25,  Accounting  for Stock Issued to Employees,  and
related  interpretations  in accounting for its stock options and,  accordingly,
has presented the  disclosure-only  information  as required by SFAS 123. If the
Company  had  elected  to  recognize  compensation  cost based on the fair value
method of SFAS 123, the  Company's  net loss  applicable to common stock and net
loss per common share for the years ended September 30, 1999 and 1998 would have
been the pro forma amounts indicated in the following table:

<TABLE>
<CAPTION>
Year ended September 30,                                          1999              1998
- ------------------------------------------------------------------------------------------
<S>                                                           <C>             <C>
Net loss applicable to common stock - as reported             $ (745,459)     $(1,775,841)
Net loss applicable to common stock - pro forma               $ (842,614)     $(1,890,395)
Net loss per common share - basic and diluted - as reported   $    (0.10)     $     (0.23)
Net loss per common share - basic and diluted- pro forma      $    (0.11)     $     (0.24)
</TABLE>

At  September  30,  1999,  by range of  exercise  prices,  the  number of shares
represented by outstanding  options with their weighted  average  exercise price
and weighted  average  remaining  contractual  life, in years, and the number of
shares  represented by exercisable  options with their weighted average exercise
price are as follows:



                                      F-12
<PAGE>

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                                 Bio-Imaging Technologies, Inc. and Subsidiaries

<TABLE>
<CAPTION>
                         Options Outstanding                                     Options Exercisable
- -----------------------------------------------------------------------    -----------------------------
       Range of                      Weighted Average       Weighted                         Weighted
       Exercise         Number          Remaining           Average            Number        Average
        Prices       Outstanding     Contractual Life    Exercise Price     Exercisable   Exercise Price
- -----------------------------------------------------------------------    -----------------------------
    <S>     <C>       <C>                <C>                  <C>             <C>                 <C>
    $0.63 - $1.44     1,040,370          7.72 years           $0.87           613,166             $0.93
    $4.13 - $4.69       152,000          2.67 years           $4.66           152,000             $4.60
- -----------------------------------------------------------------------    -----------------------------
    $0.63 - $4.69     1,192,370          7.08 years           $1.34           765,166             $1.66
=======================================================================    =============================
</TABLE>

The weighted  average  fair value of options  granted in 1999 and 1998 was $0.38
and $0.53  respectively.  The fair value of each option  granted is estimated on
the  date of  grant  using  the  Black-Scholes  option  pricing  model  with the
following weighted average assumptions:

Grants for the year ended September 30,               1999             1998
- ---------------------------------------------------------------------------
Risk-free interest rate                               4.7%             4.5%
Expected dividend yield                               0.0%             0.0%
Expected volatility                                   117%             107%
Expected life in years                                6.00             6.00

On  October  13,  1994,   the  Company  and  Covance  Inc.,   formerly   Corning
Pharmaceutical  Services,  Inc., consummated the purchase by Covance Inc. of (i)
2,355,000 shares of the Company's common stock, $.00025 par value (ii) a warrant
to purchase  250,000  shares of common stock with an initial  exercise  price of
$1.25 per share and (iii) a warrant to purchase  250,000  shares of common stock
with an  initial  price of $1.50 per share  (the  "Warrants")  for an  aggregate
purchase price of $1,819,500.  The Warrants  expired on October 13, 1998 without
being exercised.

On December 14, 1995,  the Company  reserved  3,850,000  shares of the Company's
common stock for issuance upon conversion of the preferred stock and exercise of
the warrants issued to Investment Partners of America, L.P. ("IPA") (see below).

On  December  21,  1995,  IPA  purchased  (i)  416,667  shares of the  Company's
convertible  preferred  stock,  (ii) one five year  warrant to purchase  416,667
shares of the Company's  common stock at an initial  exercise price of $1.50 per
share  and  (iii)  one five  year  warrant  to  purchase  416,667  shares of the
Company's  common stock at an initial  exercise  price of $2.50 per share for an
aggregate  purchase  price of $500,000  pursuant to a purchase  agreement  dated
December 8, 1995  ("Purchase  Agreement").  The preferred stock provides for (i)
voting rights on an as-converted to common stock basis, with standard protective
provisions;   (ii)  a  liquidation   preference   of  $1.20  per  share;   (iii)
anti-dilution  protection  and  price  protection  provisions;  (iv)  cumulative
dividends of $0.096 per share per annum,  payable out of funds legally available
for the payment of dividends and only upon declaration of dividends by the Board
of  Directors of the Company;  and (v)  registration  rights with respect to the
shares of common stock issuable upon conversion of the preferred stock.



                                      F-13
<PAGE>

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                                 Bio-Imaging Technologies, Inc. and Subsidiaries

On June 26, 1996, the Company  issued to IPA, one five-year  warrant to purchase
66,667  shares of the  Company's  common stock at an initial  exercise  price of
$1.05 per share,  the fair market value of the Company's common stock at date of
issuance.  The  exercise  price of this  warrant  issued  to IPA is  subject  to
adjustment to protect against dilution in the event of certain  transactions and
has certain  piggyback  registration  rights.  As of  September  30,  1999,  the
adjusted exercise price of the warrant is $0.63.

The 8% convertible  cumulative  preferred stock is convertible into common stock
of the Company on a  one-for-one  share basis  subject to  adjustment to protect
against dilution in the event of certain  transactions.  Conversion may occur in
whole or in part during the first  five-year  period from the date of  issuance,
December 21, 1995,  at the option of the holder.  The Company may require a full
conversion  at any time after five years from date of  issuance.  The  preferred
stock has certain piggyback registration rights.

The Company is required to pay  semiannual  dividends on preferred  stock at the
rate of  approximately  $0.096 per share per annum,  and as when declared by the
Board of  Directors.  Dividends  are payable  either in cash or in the Company's
common stock at the  discretion of the Company.  At September 30, 1999,  accrued
preferred dividends aggregated  approximately  $10,000 or $0.02 per share of the
preferred stock.

The preferred  stockholders are entitled to vote on all matters submitted to the
vote of the common  stockholders  and are  included in  determining  quorums and
voting results.

5.  COMMITMENTS

The  Company  has  entered  into  noncancelable   operating  leases  for  office
facilities which expire through January 2005.

Future minimum  aggregate  rental payments on the  noncancelable  portion of the
lease are as follows:

Year ending September 30,
          2000                                       $ 260,475
          2001                                         317,924
          2002                                         326,368
          2003                                         334,808
          2004                                         343,244
          2005                                         115,352
==============================================================
                                                   $ 1,698,171
==============================================================

Rent expense  charged to operations  for the years ended  September 30, 1999 and
1998 approximated $249,000 and $247,000, respectively.


                                      F-14
<PAGE>

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                                 Bio-Imaging Technologies, Inc. and Subsidiaries

The Company has an employment contract with an officer which expires April 2000.
The amount due under this contract is approximately $105,000.  Additionally, the
contract  provided for the granting of options to purchase 150,000 shares of the
Company's  common stock at $0.63 which was greater than the fair market value of
the  Company's  common  stock at the  date of grant  (see  note 4).  Options  to
purchase  50,000 shares of the Company's  common stock vested  immediately,  and
25,000 on each of the first, second, third and fourth anniversary of the date of
grant.

6.  EMPLOYEE BENEFIT PLAN

On December 17, 1991, the Company  adopted the  Bio-Imaging  Technologies,  Inc.
Employees' Savings Plan (the "401(k) Plan"), a defined  contribution plan with a
cash or  deferred  arrangement.  Under the terms of the  401(k)  Plan,  eligible
employees may elect to reduce their annual compensation up to 15%, subject to an
annual limit prescribed by the Internal  Revenue  Service.  The Company may make
discretionary  matching contributions either in common stock or in cash, subject
to plan limits. The Company did not make a matching contribution to this account
for the years ended September 30, 1999 and 1998.

7.  MAJOR CUSTOMERS

Two customers  accounted for approximately 17% and 14% of accounts receivable at
September 30, 1999 and three customers  accounted for approximately 20%, 19% and
13% of accounts receivable at September 30, 1998.

Revenue from three major customers  accounted for approximately 16%, 13% and 11%
of project  revenues for the year ended  September 30, 1999 and revenue from two
major customers  accounted for approximately 26% and 24% of project revenues for
the year ended September 30, 1998.

8.  INCOME TAXES

The Company has net operating loss  carryforwards  of  approximately  $6,541,000
which expire in various years through  2018.  The deferred  income tax assets at
September  30,  1999  and  1998  of  approximately  $2,600,000  and  $2,400,000,
respectively,  represent the tax effect of the net operating loss carryforwards.
Due to the  uncertainty  regarding the ultimate amount of income tax benefits to
be derived from the net operating loss  carryforwards,  the Company has recorded
valuation  allowances against the entire deferred tax asset. The Company may not
be able to utilize the New Jersey net operating loss  carryforwards  as a result
of moving the corporate headquarters to Pennsylvania.


                                      F-15
<PAGE>

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                                 Bio-Imaging Technologies, Inc. and Subsidiaries

9.  FOREIGN OPERATIONS

Foreign  customers  accounted for  approximately 32% of project revenues for the
years ended September 30, 1999 and 1998.

10. NON-RECURRING CHARGES

In February 1998, the Company  engaged in a proxy contest in an effort to, among
other  things,  elect the members of the  Company's  Board of  Directors  at the
Annual Meeting of Stockholders  held on February 27, 1998. Costs associated with
the proxy  contest  and  related  litigation  were  $320,000  for the year ended
September  30, 1998.  In  addition,  the Company  incurred  expenses of $277,000
consisting of  restructuring  costs of $105,000 and severance  costs of $172,000
during the year ended September 30, 1998.

The  restructuring  costs were  associated  with the termination of two business
divisions,  the Marketing  Information Services Division and the Data Management
and Information  Systems Division,  by the Company in December 1997. These costs
consisted of $38,000 of severance  costs and $67,000 related to the write-off of
assets and costs associated with the termination of the divisions.

In a separate matter, two executive officers of the Company resigned in December
1997.  The Company  entered  into a  separation  agreement  with one such former
executive  officer  requiring  the  Company to pay him  $127,000 of which $0 and
$30,000  remains  payable at  September  30, 1999 and 1998,  respectively.  As a
result  of these  resignations,  the  Company  recorded  severance  expenses  of
approximately $172,000 during the year ended September 30, 1998.



                                      F-16



                               OFFICE SPACE LEASE

                                       for

                            826 NEWTOWN-YARDLEY ROAD

                                 by and between

                          YARDLEY ROAD ASSOCIATES, L.P.
                                  (as Landlord)

                                       and

                         BIO-IMAGING TECHNOLOGIES, INC.
                                   (as Tenant)


                            Date: September 22, 1999

<PAGE>



     THIS LEASE (the  "Lease")  is made the 22 day of  September,  1999  between
Yardley Road Associates,  L.P. (herein referred to as "Landlord")  whose address
is  1101  West  DeKalb  Pike,   Suite  200,  Wayne,  PA  19087  and  Bio-Imaging
Technologies, Inc. (herein referred to as "Tenant") whose address is ----------

                                    PREAMBLE
                                    --------

                     BASIC LEASE PROVISIONS AND DEFINITIONS

     In addition to other terms elsewhere  defined in this Lease,  the following
terms whenever used in this Lease shall have only the meanings set forth in this
section,  unless  such  meanings  are  expressly  modified,  limited or expanded
elsewhere herein.

1.   ADDITIONAL RENT shall mean all sums in addition to Fixed Basic Rent payable
     ---------------
by Tenant to Landlord or to third  parties  pursuant  to the  provisions  of the
Lease.

2.   BROKER(S) shall mean Kelley & Associates, Inc. and Insignia/ESG, Inc.
     ---------

3.   BUILDING  shall mean 826 Newtown  Yardley Road,  Newtown,  Pennsylvania  as
     --------
described on Exhibit A hereto.

4.   BUILDING HOLIDAYS shall be those shown on Exhibit D.
     -----------------

5.   DEMISED PREMISES OR PREMISES shall be approximately  sixteen thousand eight
     ----------------------------
hundred and eighty one (16,881) gross  rentable  square feet on the ground level
of the Building  which includes an allocable  share of the Common  Facilities as
defined in Section 2, which  measurement  shall be subject to final  measurement
and agreement.

6.   EXHIBITS  shall be the following,  attached to this Lease and  incorporated
     --------
herein and made a part hereof:

                  Rider A                   Renewal Options
                  Exhibit A                 Location of Premises
                  Exhibit A-1               Office Building Area
                  Exhibit B                 Rules and Regulations
                  Exhibit C                 Landlord's Work
                  Exhibit D                 Building Holidays
                  Exhibit E                 Tenant Estoppel Certificate

7.   EXPIRATION  DATE shall be the last day of the month which is sixty two (62)
     ----------------
consecutive  calendar  months  following  the  Commencement  Date (as defined in
Section 4 of the Lease).



                                       i
<PAGE>

8.   FIXED BASIC RENT shall be calculated and payable as follows:
     ----------------

               Rentable        Rate Per            Yearly              Monthly
   Months       Sq. Ft.        Rentable             Rate             Installment
                               Sq. Foot

    1-2         16,881         $ 0                n/a                  n/a
    3-14        16,881         $ 18.50          $ 312,298.50        $  26,024.88
    15-26       16,881         $ 19.00          $ 320,739.00        $  26,728.25
    27-38       16,881         $ 19.50          $ 329,179.50        $  27,431.63
    39-50       16,881         $ 20.00          $ 337,620.00        $  28,135.00
    51-62       16,881         $ 20.50          $ 346,060.50        $  28,838.38

9.   OFFICE BUILDING AREA is as set forth on Exhibit A-1
      -------------------

10.  PERMITTED USE shall be general office use and for no other purpose.
     -------------

11.  PROPORTIONATE SHARE shall mean 14.19 percent which is 16,881, the number of
     -------------------
rentable square feet contained in the Premises divided by 119,000, the number of
rentable square feet contained within the Building.

12.  SECURITY  DEPOSIT  shall be two (2) months Fixed Basic Rent which may be in
     -----------------
the form of an  irrevocable  evergreen  letter of  credit  in a form  reasonably
acceptable to Landlord.

13.  TARGET DATE shall be December 1, 1999.
     -----------

14.  TERM  shall mean five (5) years and two (2)  months  from the  Commencement
     ----
Date (as  defined in  Section 4 of the  Lease)  unless  terminated  or  extended
pursuant to any option or provision contained herein.


                                       ii
<PAGE>

                                TABLE OF CONTENTS

         Section                                                            Page

1.       Definitions.........................................................1
2.       Premises............................................................1
3.       Completion of Premises..............................................1
4.       Term................................................................2
5.       Use of Premises.....................................................2
6.       Rent................................................................2
7.       Insurance...........................................................5
8.       Repairs and Maintenance.............................................6
9.       Utilities and Services..............................................7
10.      Governmental Regulations............................................9
11.      Signs...............................................................9
12.      Alterations, Additions and Fixtures................................10
13.      Mechanic's Liens...................................................10
14.      Landlord's Right of Entry..........................................11
15.      Damage by Fire or Other Casualty...................................12
16.      Non-Abatement of Rent..............................................13
17.      Indemnification....................................................13
18.      Condemnation.......................................................14
19.      Quiet Enjoyment....................................................15
20.      Rules and Regulations..............................................15
21.      Assignment and Sublease............................................15
22.      Tenant's Relocation................................................18
23.      Subordination......................................................19
24.      Curing Tenant's Defaults...........................................20
25.      Surrender..........................................................20
26.      Defaults-Remedies..................................................20
27.      Condition of Premises..............................................23
28.      Hazardous Substances...............................................24
29.      Recording..........................................................24
30.      Broker's Commission................................................24
31.      Notices............................................................25
32.      Irrevocable Offer, No Option.......................................26
33.      Landlord Inability to Perform......................................26
34.      Survival...........................................................26
35.      Corporate Tenants..................................................26
36.      Tenant Representations and Warranties..............................26
37.      Waiver of Invalidity of Lease......................................26
38.      Security Deposit...................................................26
39.      Estoppel Certificate...............................................27
40.      Rights Reserved by Landlord........................................27
41.      Miscellaneous......................................................29
42.      Additional Definitions.............................................30
43.      Tenant's Right of First Offer .....................................31


                                       4
<PAGE>


     For and in consideration of the covenants  herein  contained,  and upon the
terms and  conditions  herein set forth,  Landlord  and Tenant,  intending to be
legally bound, agree as follows:

     1. DEFINITIONS.  The definitions set forth in the preceding  Preamble shall
apply  to  the  same  capitalized  terms  appearing  in  this  Lease  Agreement.
Additional definitions are contained in Section 42 and throughout this Lease.

     2. PREMISES.  Landlord hereby demises and leases the Premises to Tenant and
Tenant  hereby  leases and takes the  Premises  from  Landlord  for the Term (as
defined in Section 4) and upon the terms, covenants,  conditions, and provisions
set forth in this Lease  Agreement,  including the Preamble (this "Lease").  The
Tenant's  interest in the Premises as tenant shall include the right,  in common
with Landlord and other occupants of the Building, to use driveways,  sidewalks,
loading and parking areas (which parking areas provide unreserved parking spaces
at the ratio of four (4) parking spaces for every one thousand  rentable  square
feet of space within the Building), lobbies, hallways and other facilities which
are located within the Property  (defined in Section 6) and which are designated
by Landlord  from time to time for the use of all of the tenants of the Building
(the "Common Facilities").

     3.  COMPLETION OF PREMISES.  The Premises  shall be completed in accordance
with the plans and  specifications  attached  hereto as Exhibit C (herein called
the  "Plans")  at  Landlord's  expense.  All  necessary  construction  shall  be
commenced promptly following  Landlord's  execution and acceptance of this Lease
and  Tenant's  delivery of the first  month's  Fixed Basic Rent and the Security
Deposit  to  Landlord  and shall be  substantially  completed  ready for use and
occupancy  by Tenant on the  Target  Date set forth in the  Preamble;  provided,
however,  that the time for  substantial  completion  of the  Premises  shall be
extended  for  additional  periods of time equal to the time lost by Landlord or
Landlord's  contractors,  subcontractors  or  suppliers  due to strikes or other
labor   troubles;   delays  in  Tenant's   selection  of  materials,   plans  or
specifications;  governmental  restrictions and limitations;  unavailability  or
delays in obtaining fuel, labor or materials;  war or other national  emergency;
accidents; floods; defective materials; fire damage or other casualties; adverse
weather  conditions;  the  inability  to obtain  building  or use and  occupancy
permits; or any cause similar or dissimilar to the foregoing which is beyond the
reasonable  control of Landlord or  Landlord's  contractors,  subcontractors  or
suppliers.  The Premises shall be deemed substantially  completed when Tenant is
in receipt of a Certificate  of Occupancy or Temporary  Certificate of Occupancy
(punchlist  items  excepted).  All  construction  shall  be done  in a good  and
workmanlike  manner  and  shall  comply  at the  time  of  completion  with  all
applicable and lawful laws,  ordinances,  regulations and orders of the federal,
state,  county or other governmental  authorities having  jurisdiction  thereof,
including the Americans With Disabilities Act. Tenant and its authorized agents,
employees and contractors  shall have the right,  at Tenant's own risk,  expense
and  responsibility,  at all  reasonable  times  prior  to the  Target  Date  as
hereinafter   defined,   to  enter  the  Premises  for  the  purpose  of  taking
measurements and installing its furnishings and equipment; provided that Tenant,
in so  doing,  shall  not  interfere  with or  delay  the  work to be  performed
hereunder by Landlord, and Tenant shall use contractors



<PAGE>

and workmen  compatible  with the contractors and workmen engaged in the work to
be performed  hereunder by Landlord,  and Tenant shall have obtained  Landlord's
written  consent to installing any  furnishings or equipment.  If Landlord shall
fail to deliver  possession  of the  Premises by the Target Date for any reason,
whether or not within Landlord's  control,  Landlord shall not be subject to any
liability  to Tenant.  No failure to deliver the  Premises by the Target Date or
any other date shall in any respect  affect the validity or  continuance of this
Lease of any  obligation  of Tenant  hereunder  or extend the Term of the Lease.
Notwithstanding  the foregoing,  in the event  Landlord  fails to  substantially
complete  the Premises as set forth above on or before  December 31, 1999,  then
commencing on January 1, 2000 and terminating on the Commencement Date, Landlord
shall  reimburse  Tenant for Tenant's  increased  rental  obligations  under its
current lease arising  solely as a result of Landlord's  delay in delivering the
Premises to Tenant as provided herein.  Tenant shall be responsible for all such
increased  rental  obligations for any period prior to January 1, 2000 and shall
use its good faith  efforts to  negotiate a reduction  in such  obligations.  In
addition to the  foregoing,  if Landlord  fails to  substantially  complete  the
Premises as set forth above prior to February 29, 2000,  (the  "Outside  Date"),
then Tenant may terminate  this Lease upon thirty (30) days prior written notice
to Landlord and upon such termination,  Landlord shall refund to Tenant all sums
Tenant  paid to  Landlord  on account of Rent and  neither  party shall have any
further obligations hereunder.  Tenant's notice may be given at anytime prior to
the Outside  Date,  but shall only be  effective  as of the Outside Date or such
later date as specified in Tenant's notice. If Landlord substantially  completes
the Premises prior to the date of  termination as set forth in Tenant's  notice,
then such notice shall be deemed  revoked and the parties  hereto shall continue
to be bound to the terms of this Lease. Notwithstanding the foregoing, if Tenant
fails to deliver to Landlord  final  approved Plans (as defined above) which are
acceptable to Landlord on or before  September 17, 1999,  then each of the dates
set forth in this  Section 3 shall be  extended  by one (1) day for each one (1)
day of delay  beyond  September  17,  1999  until such  Plans are  delivered  to
Landlord.

     4.  TERM.  The  Term  of  this  Lease  shall  commence  on  the  date  (the
"Commencement  Date")  which is the first to occur of (a) the date the  Premises
are deemed  substantially  completed  as provided in Section 3 above and (b) the
date on which the  Premises  are  actually  occupied  by Tenant.  Following  the
Commencement Date, the Term of this Lease, unless sooner terminated as expressly
provided in this Lease,  shall continue until the date of expiration of the term
specified  as the Term of Lease in the  Preamble  plus the  number of days which
remain in the  calendar  month in which such term  expires  (the  "Term").  Upon
request of Landlord,  Tenant shall enter into a memorandum agreement stipulating
the actual Commencement Date of the Term.

     5. USE OF PREMISES.  Tenant shall occupy the Premises  throughout  the Term
and shall use the same for, and only for,  the  Permitted  Use  specified in the
Preamble.   The  Building  is  designed  to  normal   building   standards   for
floor-loading capacity. Tenant shall not use the Premises in such ways which, in
Landlord's judgment, exceed such load limits.

     6. RENT. Unless otherwise  specifically  requested by Landlord at any time,
Fixed

                                       2
<PAGE>

Basic  Rent,  Additional  Rent and any other  rent or other  sums due under this
Lease (hereunder  collectively  referred to as Rent) shall be paid and delivered
to Landlord's property manager,  if any, as agent for Landlord,  in the amounts,
time and manner more particularly provided in this Lease.

          a. FIXED BASIC RENT. Commencing on the Commencement Date, Tenant shall
pay,  throughout  the Term,  Fixed  Basic  Rent in the amount  specified  in the
Preamble,  without  notice or demand and without  setoff or deduction,  in equal
monthly  installments equal to one-twelfth of the Fixed Basic Rent (specified as
Monthly  Installments  in the  Preamble),  in advance,  on the first day of each
calendar  month during the Term. If the  Commencement  Date falls on a day other
than  the  first  day of a  calendar  month,  the  Fixed  Basic  Rent  shall  be
apportioned on a per diem basis for the period between the Commencement Date and
the first day of the first full calendar month in the Term and such  apportioned
sum shall be paid on the Commencement Date.

          b. ADDITIONAL RENT.  Commencing on the Commencement Date, Tenant shall
pay to Landlord,  as Additional Rent, in the manner more  particularly set forth
below, Tenant's Proportionate Share of Annual Operating Costs (as defined below)
for the Property to the extent same exceeds the sum of Four Dollars ($4.00) (the
"Expense Stop") per rentable square foot of the Premises:

               i) ANNUAL  OPERATING  COSTS.  The term "Annual  Operating  Costs"
shall mean all costs Landlord incurs from owning,  operating and maintaining the
Building and the lot or tract of land on which it is situated (the  "Property").
Annual Operating Costs shall include,  by way of example rather than limitation:
insurance costs,  including premiums;  fees;  Impositions (defined below); costs
for repairs,  maintenance and service contracts;  management fees;  landscaping;
snow removal;  governmental  permits fees; costs of compliance with governmental
orders  and  regulations;   administrative  and  overhead  expenses;   costs  of
furnishing water, sewer, electricity, gas, fuel, and other utility services, for
use in  Common  Facilities  of the  Building  and  Property;  and  the  cost  of
janitorial service and trash removal; excluding,  however, from Annual Operating
Costs the following:  costs which are treated as capital expenditures (except as
provided  in  Sections  9(d)  and10(b))  under  generally  accepted   accounting
principles;  mortgage debt or ground rents  incurred by Landlord as owner of the
Property;  income,  excess  profits,  corporate  capital  stock or franchise tax
imposed or assessed upon Landlord,  unless such tax or any similar tax is levied
or assessed,  in lieu of all or any part of any currently existing Imposition or
an  increase  in  any  currently  existing   Imposition;   leasing  commissions,
accountants',  consultants' or attorneys' fees, costs and disbursement and other
expenses  incurred in connection  with  negotiations or disputes with tenants or
prospective  tenants or  associated  with the  enforcement  of any leases or the
defense of Landlord's  title to or interest in the Building in  connection  with
any proceedings  involving real property taxes other than disputes regarding tax
assessment and reduction of real property  taxes;  costs of  construction of the
Building and related facilities and correction of defects in construction of the
Building (including permit,  license and inspection fees); costs of any items or
services sold or provided to tenants  (including  Tenant) for which  Landlord is
entitled to be reimbursed by such tenants or which are not

                                       3
<PAGE>

generally  provided to all  tenants of the  Building;  fees and higher  interest
charges  caused by  Landlord's  refinancing  the  Building;  all  repairs to the
interior of the Building of a structural  nature (not made  necessary by unusual
use by Tenant); costs incurred due to violation by Landlord or any tenant of the
terms and  conditions  of any  lease;  overhead  and  profit  increment  paid to
subsidiaries  or  affiliates  of  Landlord,  or to any  party as a  result  of a
noncompetitive  selection process, for management or other services on or to the
Building  or for  supplies or other  materials,  to the extent that the costs of
such services,  supplies or materials exceed the costs that would have been paid
had the services, supplies or materials been provided by unaffiliated parties on
a  competitive  basis;  general  overhead  and  administrative  expenses  except
salaries of on-site property manager,  management secretary and maintenance man;
any  compensation  paid to clerks,  attendants  or other  persons in  commercial
concessions operated by Landlord, rentals and other related expenses incurred in
leasing  air  conditioning  systems,  elevators  or other  equipment  ordinarily
considered  to be for a  capital  nature,  except  equipment  which  is  used in
providing  janitorial  services  and which is not affixed to the  Building;  all
items and services for which Tenant reimburses Landlord or pays third persons or
which Landlord  provides  selectively to one or more tenants or occupants of the
Building (other than Tenant) without  reimbursement;  commissions,  advertising,
and  promotional  expenditures.  "Impositions"  shall  mean all  levies,  taxes,
assessments,  charges,  imposts,  and  burdens,  of  whatever  kind and  nature,
ordinary and extraordinary, which are assessed or imposed during the Term by any
federal,  state or municipal  government  or public  authority or under any law,
ordinance  or  regulation  thereof or  pursuant  to any  recorded  covenants  or
agreements  upon or with  respect  to the  Property  or any  part  thereof,  any
improvements  thereto,  any personal property necessary to the operation thereof
and owned by Landlord or this Lease.

               ii) ESTIMATED  PAYMENTS - EXPENSE  STATEMENT AND  RECONCILIATION.

               (1)  Landlord  shall  submit  to  Tenant  as soon  as  reasonably
possible after the beginning of each calendar year of the Term, the following:

                    (a) a statement setting forth (i) the Annual Operating Costs
for the previous  calendar year of the Term and (ii) a  calculation  of Tenant's
Proportionate  Share of the  increase  in the  Annual  Operating  Costs over the
Expense Stop for the previous calendar year (the "Expense Statement"); and

                    (b) a statement  of  Landlord's  good faith  estimate of the
Annual  Operating  Costs for the  current  calendar  year and a  calculation  of
Tenant's  Proportionate Share of the increase in the Annual Operating Costs over
the Expense Stop for the current calendar year ("Tenant's Estimated Share").

               (2) Beginning  with the next  installment of Fixed Basic Rent due
after the delivery of the aforesaid  statements  to Tenant,  Tenant shall pay to
Landlord,  on account of its  Proportionate  Share of the increase in the Annual
Operating Costs over the Expense Stop, the following:

                                       4
<PAGE>

                    (a) a sum  equal to the  product  of  one-twelfth  (1/12) of
Tenant's  Estimated  Share and the number of calendar  months elapsed during the
current  calendar year up to and  including the month payment is made,  plus any
amounts due from Tenant to Landlord on account of Annual Operating Costs for any
prior period(s) of time, less

                    (b) a sum equal to the  amount,  if any, by which the sum of
all payments made by Tenant to Landlord on account of Annual Operating Costs for
the  previous  calendar  year exceed  those  actually  specified  in the Expense
Statement.

               (3) On the first day of each succeeding calendar month until such
time as Tenant  receives a new  Expense  Statement  and  statement  of  Tenant's
Estimated Share,  Tenant shall pay to Landlord,  on account of its Proportionate
Share of Annual Operating Costs, one-twelfth (1/12) of the then current Tenant's
Estimated Share. Any payment due from Tenant to Landlord, or any refund due from
Landlord to Tenant,  on account of Annual  Operating Costs not yet determined as
of the  expiration  of the Term  shall be made  within  thirty  (30) days  after
submission to Tenant of the next Expense Statement.

          c)  DISPUTES.  Unless  Tenant,  within  ninety  (90)  days  after  any
statement of Additional  Rent is  furnished,  shall give notice to Landlord that
Tenant disputes said statement, specifying in detail the basis for such dispute,
each  statement  furnished  to Tenant by Landlord  under any  provision  of this
Section  shall  be  conclusively  binding  upon  Tenant  as  to  the  particular
Additional Rent due from Tenant for the period  represented  thereby;  provided,
however,  that  additional  amounts  due  may  be  required  to be  paid  by any
supplemental  statement  furnished by  Landlord.  Tenant shall have the right at
reasonable  times  to  examine  the  records  used  in  making  the  aforestated
determinations, upon written notice in advance; provided, however, such disputed
amount  shall  have  been  paid by  Tenant  to  Landlord.  In the event any such
examination  shall  reveal  an  adverse  variance  in excess of 10% of the total
operating expenses of which Tenant is required to pay their Proportionate Share,
Landlord  shall  reimburse  Tenant for the reasonable  cost of such  examination
within  thirty  (30) days  after  demand.  Tenant  shall  make all  payments  of
Additional  Rent without delay and  regardless  of any pending  dispute over the
amount  of  Additional  Rent  that  is due in  accordance  with  the  statements
furnished by Landlord. Landlord shall have the right to retain Tenant's security
deposit until all Additional Rent payable by Tenant is determined and paid.

     7. INSURANCE.

          a)  LIABILITY.  Tenant,  at  Tenant's  sole  cost and  expense,  shall
maintain and keep insurance in effect  throughout the Term against liability for
bodily injury  (including death) and property damage in or about the Premises or
the Property under a policy of comprehensive general public liability insurance,
with such limits as to each as may be reasonably  required by Landlord from time
to time, but not less than  $2,000,000.00  for each person and  $5,000,000.00 in
the aggregate for bodily  injury  (including  death) to more than one (1) person
and $2,000,000.00 for property damage. The policies of

                                       5
<PAGE>

comprehensive  general public liability insurance shall name Landlord and Tenant
(and if requested,  any mortgagee of Landlord) as the insured parties. Each such
policy  shall  provide that it shall not be  cancelable  without at least thirty
(30) days prior  written  notice to Landlord  and to any  mortgagee  named in an
endorsement thereto and shall be issued by an insurer and in a form satisfactory
to  Landlord.  At  least  ten (10)  days  prior to the  Commencement  Date,  and
thereafter  upon  Landlord's  request,  a  certificate  of  insurance  shall  be
delivered to Landlord  proving  compliance with the foregoing  requirements.  If
Tenant shall fail, refuse or neglect to obtain or to maintain any insurance that
it is required to provide or to furnish Landlord with  satisfactory  evidence of
coverage  on any such  policy  upon  demand,  Landlord  shall  have the right to
purchase such insurance.  All payments made by Landlord for such insurance shall
be  recoverable  by Landlord from Tenant,  together with  interest  thereon,  as
Additional Rent promptly upon demand.  Notwithstanding anything contained herein
to the contrary,  Tenant may self-insure all of its personal  property  situated
within the Premises against property damage and destruction.

          b) WAIVER OF  SUBROGATION.  The parties to this Lease each release the
other, to the extent of the releasing party's insurance  coverage,  from any and
all  liability  for any loss or damage  covered by such  insurance  which may be
inflicted  upon the  property of such party even if such loss or damage shall be
brought  about by the fault or  negligence  of the other  party,  its  agents or
employees.  If any policy  does not permit  such a release  of  liability  and a
waiver of subrogation,  and if the party to benefit therefrom requests that such
a waiver be  obtained,  the other party agrees to obtain an  endorsement  to its
insurance policies permitting such waiver of subrogation if it is available.  If
an additional premium is charged for such waiver, the party benefiting therefrom
agrees to pay the amount of such additional premium promptly upon demand. In the
event a party is unable to obtain such a waiver, it shall immediately notify the
other party of its inability.  In the absence of such notifications,  each party
shall be deemed to have obtained such waiver of subrogation.

          c)  INCREASE  OF  PREMIUMS.  Tenant will not do anything or fail to do
anything or permit  anything to be done which will cause the cost of  Landlord's
insurance to increase or which will prevent  Landlord from  procuring  insurance
(including but not limited to public liability insurance) from companies, and in
a form, satisfactory to Landlord. If any breach of this subsection (c) by Tenant
shall cause the rate of fire or other  insurance to be  increased,  Tenant shall
pay the amount of such  increase as Additional  Rent  promptly  upon demand.  If
Tenant does anything or fails to do anything or permits  anything to be done for
which  insurance  cannot be  obtained,  Landlord may  terminate  this Lease upon
written notice to Tenant.

     8. REPAIRS AND MAINTENANCE.

          a) Tenant  shall,  throughout  the Term and at Tenant's  sole cost and
expense,  keep and maintain the Premises in a neat and orderly  condition;  and,
upon  expiration of the Term,  Tenant shall leave the Premises in good order and
condition,  ordinary wear and tear, damage by fire or other casualty (which fire
or other  casualty has

                                       6
<PAGE>

not occurred  through the negligence of Tenant or those claiming under Tenant or
their agents, employees or invitees,  respectively) alone excepted, and for that
purpose  and  except as  stated,  Tenant  will make all  necessary  repairs  and
replacements.  Tenant  shall  not  permit  any  waste,  damage  or injury to the
Premises.  Tenant  shall not use or permit the use of any  portion of the Common
Facilities  for other than their  intended use as specified by the Landlord from
time to time.

          b) Landlord  shall,  throughout the Term,  make all necessary  repairs
(including  replacements)  to the structural  elements of the Premises and other
improvements  located on the Property,  including the roof and exterior walls of
the Building as well as the mechanical, HVAC, electrical and plumbing systems of
the Building not solely serving the Premises;  provided,  however, that Landlord
shall have no  responsibility  to make any  repairs  unless  and until  Landlord
receives  written  notice of the need for such repair.  Landlord  shall keep and
maintain all Common Facilities of the Property and any sidewalks, parking areas,
curbs and access ways  adjoining the Property in a clean and orderly  condition,
free of  accumulation  of dirt and  rubbish  and  shall  keep and  maintain  all
landscaped areas within the Property in a neat and orderly condition.

          c)  Notwithstanding  the foregoing,  repairs and  replacements  to the
Premises and the Property  arising out of or caused by Tenant's  use,  manner of
use or occupancy  of the  Premises,  by Tenant's  installation  of  alterations,
additions,  improvements, trade fixtures or equipment in or upon the Premises or
by any act or omission of Tenant or any employee,  agent,  contractor or invitee
of Tenant  shall be made at Tenant's  sole cost and expense and Tenant shall pay
Landlord the cost of any such repair or  replacement,  as Additional  Rent, upon
demand.

     9. UTILITIES AND SERVICES.

          a) Landlord shall furnish the Premises with  electricity,  heating and
air  conditioning  for the normal use and  occupancy  of the Premises as general
offices  between 8:00 a.m. and 6:00 p.m.,  Monday through  Friday,  of each week
during the Term (Building Holidays excepted). Tenant agrees to pay as Additional
Rent all charges for electricity, light, heat or other utility used by Tenant at
the  Premises.  If a  separate  meter is  installed,  Tenant  shall  pay for the
consumption of such utilities  based upon its metered usage. A separate meter or
submeter  shall be  installed  (as set  forth in  Exhibit  C) to meter  Tenant's
consumption  of  electricity.  If no meter is  installed,  Tenant  shall pay its
Proportionate Share of any utility charges covering the Demised Premises and the
remainder of the  Building.  Tenant shall pay all bills for  separately  metered
utility usage within ten (10) days after receipt thereof, and any non-payment or
late payment of such utility  bills shall be deemed a default under the terms of
this Lease. All charges for installation and repairs of any meters servicing the
Premises  shall be payable by Tenant as  Additional  Rent and shall be paid when
the same shall  become  due.  If Tenant  shall  require  electricity  or install
electrical  equipment  using current in excess of 110 volts or which will in any
way increase the amount of electricity  furnished by Landlord for general office
use (including but not limited to electrical heating or refrigeration  equipment
or electronic  data  processing  machines) or if Tenant shall attempt to use the


                                       7
<PAGE>

Premises in such a manner  that the  services to be  furnished  by Landlord  are
required  during periods other than the business hours specified  above,  Tenant
will obtain prior  written  approval  from  Landlord and will pay, as Additional
Rent, for the resulting  additional  direct  expense to Landlord,  including the
expense  resulting from the  installation of any equipment and meters,  promptly
upon receipt of an invoice from Landlord.

          b) Within  the  Common  Facilities  of the  Building,  Landlord  shall
furnish  reasonably:  (i) adequate  electricity,  (ii) hot and cold water, (iii)
lavatory supplies,  (iv) automatically operated elevator service, (v) normal and
customary  cleaning  services (on a five-day a week basis) after business hours,
(vi) heat and air conditioning in season, (vii) landscaping,  (viii) parking lot
maintenance,  (ix) common area maintenance and (x) snow and ice removal.  Tenant
shall be responsible for its Proportionate  Share of such services in accordance
with Section 6(b)  hereof.  Landlord  shall  provide  janitorial  service to the
Premises,  five days per week,  after regular  business hours,  and the costs of
such service will be passed through to Tenant as set forth in Section 6.

          c) Landlord  shall not be liable for any  damages to Tenant  resulting
from  the  quality,  quantity,  failure,  unavailability  or  disruption  of any
services  beyond  the  reasonable  control  of  Landlord  and the same shall not
constitute a termination of this Lease or an actual or constructive  eviction or
entitle Tenant to an abatement of rent.  Landlord  shall not be responsible  for
providing   any   services  not   specifically   provided  for  in  this  Lease.
Notwithstanding  anything  to the  contrary  contained  in  this  Lease,  if (i)
Landlord  ceases to furnish any  service in the  Building,  and Tenant  notifies
Landlord of such  cessation in writing (the  "Interruption  Notice"),  (ii) such
cessation  does not arise as a result of the gross  negligence  of Tenant  (iii)
such  cessation is not caused by a fire or other casualty (in which case Section
15 shall control),  (iv) the repair or restoration of such service is reasonably
within  the  control of  Landlord,  and (v) as a result of such  cessation,  the
Premises or material  portion  thereof,  is rendered  untenatable  (meaning that
Tenant is unable to use the  Premises or a  substantial  portion  thereof in the
normal course of its  business) and Tenant,  in fact ceases to use the Premises,
or material  portion thereof,  then,  commencing on the fifth (5th) Business Day
after the later to occur of the date the Premises (or material  portion thereof)
becomes  untenatable,  the date  Tenant  ceases  to use such  space and the date
Tenant provides Landlord with an Interruption  Notice,  all rent hereunder shall
be abated on a per diem basis for each day of such  interruption  based upon the
percentage of the Premises so rendered  untenantable  and not used by Tenant and
such abatement  shall continue  until the date the Premises  becomes  tenantable
again.

          d) Tenant shall pay capital  improvements which Landlord shall install
or construct for energy saving devices.  Tenant's  Proportionate  Share shall be
determined  based  upon  the  estimated  life of the  capital  investment  item,
determined  by  Landlord  in  accordance  with  generally  accepted   accounting
principles, and shall include a cost of capital funds adjustment equal to twelve
percent  (12%) per year on the  unamortized  portion of all such  costs.  Tenant
shall  only  have to pay for  the  portion  of the  useful  life of the  capital
improvement  which falls  within the Term.  Tenant  shall thus make  payments in
equal annual  installments for such capital  improvements until the Term expires
or until

                                       8
<PAGE>

the cost of the  improvement  has been fully paid for,  whichever  first occurs;
such payments shall be computed by Landlord at the time of  installation  of the
capital  improvement  in the same  manner  as  Landlord  makes  computations  of
Tenant's share of the annual operating costs pursuant to Section 6(b)(ii).

     10. GOVERNMENTAL REGULATIONS.

          a)  Landlord  and  Tenant  shall  comply  with all  laws,  ordinances,
notices,  orders, rules,  regulations and requirements of all federal, state and
municipal government or any department, commission, board of officer thereof, or
of the National Board of Fire Underwriters or any other body exercising  similar
functions,  relating  to the  Premises  or to the  use or  manner  of use of the
Property.  Tenant  shall not  knowingly  do or  commit,  or suffer to be done or
committed  anywhere  in the  Building,  any act or thing  contrary to any of the
laws,  ordinances,  regulations  and  requirements  referred to in this Section.
Tenant shall give Landlord prompt written notice of any accident in the Premises
and of any  breakage,  defect or  failure  in any of the  systems  or  equipment
servicing the Premises or any portion of the Premises.

          b) Tenant  shall pay its  Proportionate  Share of the cost of  capital
improvements  which  Landlord  shall  install or  construct in  compliance  with
governmental  requirements  which take effect after the commencement of the Term
hereof  or as energy  saving  devices.  Tenant's  Proportionate  Share  shall be
determined  based  upon  the  estimated  life of the  capital  investment  item,
determined  by  Landlord  in  accordance  with  generally  accepted   accounting
principles, and shall include a cost of capital funds adjustment equal to twelve
percent  (12%) per year on the  unamortized  portion of all such  costs.  Tenant
shall  only  have to pay for  the  portion  of the  useful  life of the  capital
improvement  which falls  within the Term.  Tenant  shall thus make  payments in
equal annual  installments for such capital  improvements until the Term expires
or until the cost of the  improvement  has been fully paid for,  whichever first
occurs;  such payments shall be computed by Landlord at the time of installation
of the capital  improvement in the same manner as Landlord makes computations of
Tenant's share of the annual operating costs pursuant to Section 6(b)(ii).

          c) Tenant shall pay all taxes imposed upon Tenant's furnishings, trade
fixtures, equipment or other personal property.

     11. SIGNS. Except for signs which are located wholly within the interior of
the Premises and which are not visible from the exterior of the Premises, Tenant
shall not place,  erect,  maintain  or paint any signs upon the  Premises or the
Property unless the design of such signs are approved by Landlord in writing and
comply with all applicable  governmental rules,  regulating  ordinances or other
statutes.  Tenant  shall  be  solely  responsible  for all  costs  and  expenses
associated  with the  erection  of any  signs  upon the  Premises  and  shall be
obligated to obtain and provide to Landlord any and all necessary  permits prior
to the  placement  or  erection of such signs.  Notwithstanding  the  foregoing,
Tenant shall be permitted to place its name on the Building directory.

                                       9
<PAGE>

     12. ALTERATIONS, ADDITIONS AND FIXTURES.

          a) Tenant  shall have the right to install in the  Premises  any trade
fixtures;  provided,  however,  that no such installation and no removal thereof
shall be permitted  which  affects any  structural  component of the Building or
Premises  and that Tenant  shall  repair and restore any damage or injury to the
Premises or the Property caused by installation or removal.

          b)  Tenant  shall  not  make or  permit  to be made  any  alterations,
improvements  or additions to the Premises or Property  without on each occasion
first presenting plans and  specifications to Landlord and obtaining  Landlord's
prior written consent,  which shall not be unreasonably withheld or delayed, but
may be conditioned  upon  compliance  with  reasonable  requirements of Landlord
including, without limitation, the filing of mechanics' lien waivers by Tenant's
contractors  and the  submission  of  written  evidence  of  adequate  insurance
coverage  naming  Landlord  as an  additional  insured  thereunder.  If Landlord
consents to any  proposed  alterations,  improvements  or  additions or Tenant's
contractor  performs  any of the work  identified  in  Section  3 of this  Lease
Agreement,  then Tenant shall make the proposed  alterations,  improvements  and
additions at Tenant's sole cost and expense  provided that: (i) Tenant  supplies
any  necessary  permits;  (ii) such  alterations  and  improvements  do not,  in
Landlord's judgment, impair the structural strength of the Building or any other
improvements  or reduce the value of the Property;  (iii) Tenant takes or causes
to be taken all steps that are  otherwise  required  by Section 13 of this Lease
and that are required or permitted  by law in order to avoid the  imposition  of
any  mechanic's,  laborer's  or  materialman's  lien  upon the  Premises  or the
Property; (iv) Tenant uses a contractor reasonably approved by Landlord; (v) the
occupants of the Building and of any adjoining real estate owned by Landlord are
not unreasonbly annoyed or disturbed by such work such that the conduct of their
business is interefered with ; (vi) the  alterations,  improvements or additions
shall be installed in accordance with the approved plans and  specifications and
completed according to a construction  schedule approved by Landlord;  and (vii)
Tenant  provides  insurance  of the  types  and  coverage  amounts  required  by
Landlord.  Any and all  alterations,  improvements and additions to the Premises
which are  constructed,  installed  or  otherwise  made by  Tenant  shall be the
property of Tenant until the expiration or sooner  termination of this Lease; at
that time all such  alterations  and additions  shall remain on the Premises and
become the property of Landlord  without  payment by Landlord  unless,  upon the
termination of this Lease,  Landlord  instructs  Tenant in writing to remove the
same in which  event  Tenant  will remove  such  alterations,  improvements  and
additions,  and repair and  restore  any  damage to the  Property  caused by the
installation or removal.  Notwithstanding  anything to the contrary contained in
this Lease,  Landlord may  withhold  its  approval to any proposed  alterations,
additions or  improvements  to the Premises in its absolute and sole  discretion
with respect to any such  alteration,  addition or  improvement  which  Landlord
determines   involves  any  modification  to  the  Building's  exterior  or  its
structural,  electrical,  mechanical  or  plumbing  systems,  or any  components
thereof.

     13.  MECHANIC'S  LIENS.  Tenant  shall  promptly  pay any  contractors  and
materialmen who supply labor, work or materials to Tenant at the Premises or the

                                       10
<PAGE>

Property so as to minimize the  possibility  of a lien attaching to the Premises
or the Property.  Tenant shall take all steps permitted by law in order to avoid
the  imposition  of any  mechanic's,  laborer's or  materialman's  lien upon the
Premises  or the  Property.  Should any such lien or notice of lien be filed for
work  performed for Tenant other than by Landlord,  Tenant shall cause such lien
or  notice of lien to be  discharged  of record  by  payment,  deposit,  bond or
otherwise  within  thirty (30) days after the filing  thereof or after  Tenant's
receipt of notice thereof,  whichever is earlier,  regardless of the validity of
such  lien or  claim.  If Tenant  shall  fail to cause  such lien or claim to be
discharged  and removed  from record  within such thirty (30) day period,  then,
without  obligation to investigate  the validity  thereof and in addition to any
other  right or  remedy  Landlord  may  have,  Landlord  may,  but  shall not be
obligated  to,  contest the lien or claim or discharge  it by payment,  deposit,
bond or otherwise;  and Landlord shall be entitled to compel the  prosecution of
an action for the  foreclosure  of such lien by the lienor and to pay the amount
of the judgment in favor of the lienor with  interest and costs.  Any amounts so
paid by  Landlord  and all costs and  expenses  including,  without  limitation,
attorneys'  fees  incurred by Landlord in  connection  therewith,  together with
interest at a rate of twelve percent (12%) per annum from the  respective  dates
of Landlord's making such payment or incurring such cost or expense, which shall
constitute  Additional  Rent payable  hereunder  promptly upon demand  therefor.
Nothing in this Lease is intended to authorize Tenant to do or cause any work or
labor to be done or any  materials  to be supplied  for the account of Landlord,
all of the same to be solely  for  Tenant's  account  and at  Tenant's  risk and
expense.  Further,  notwithstanding  anything to the contrary  contained in this
Lease,  nothing  contained in or  contemplated  by this Lease shall be deemed or
construed  in any way to  constitute  the consent or request by Landlord for the
performance of any work or services or the furnishing of any materials for which
any lien could be filed  against the Premises or the Building or the Property or
any part of any thereof,  nor as giving Tenant any right,  power or authority to
contract or permit the  performance of any work or services or the furnishing of
any  materials  for which any lien  could be filed  against  the  Premises,  the
Building,  the  Property or any part of any thereof.  Throughout  this Lease the
term "mechanic's lien" is used to include any lien, encumbrance or charge levied
or imposed upon the  Premises or the Property or any interest  therein or income
therefrom  on account of any  mechanic's,  laborer's  or  materialman's  lien or
arising  out of  any  debt  or  liability  to or  any  claim  or  demand  of any
contractor, mechanic, supplier, materialman or laborer and shall include without
limitation any mechanic's  notice of intention given to Landlord or Tenant,  any
stop order  given to  Landlord  or  Tenant,  any notice of refusal to pay naming
Landlord or Tenant and any injunctive or equitable  action brought by any person
entitled to any mechanic's lien.

     14. LANDLORD'S RIGHT OF ENTRY.

          a) Tenant shall permit Landlord and the authorized  representatives of
Landlord and of any mortgagee or any prospective mortgagee to enter the Premises
at all  reasonable  times,  with prior notice to Tenant,  for the purpose of (i)
inspecting the Premises or (ii) making any necessary  repairs to the Premises or
to the Building and performing any work therein. During the progress of any work
on the Premises or the  Building,  Landlord  will  attempt not to  inconvenience
Tenant, but shall not be liable for

                                       11
<PAGE>

inconvenience,  annoyance,  disturbance,  loss of  business  or other  damage to
Tenant by reason of making  any  repair or by  bringing  or  storing  materials,
supplies,  tools and  equipment in the Premises  during the  performance  of any
work,  and the  obligations  of Tenant  under  this  Lease  shall not be thereby
affected in any manner  whatsoever  unless  caused by the  negligence or willful
misconduct of the Landlord, its agents, contractors, or employees.

          b)  Landlord  shall have the right at all  reasonable  times to,  with
prior  notice to Tenant,  enter and to exhibit the  Premises  for the purpose of
inspection  or showing the Premises in  connection  with a sale or mortgage and,
during the last twelve (12) months of the Term, to enter upon and to exhibit the
Premises to any prospective tenant.

     15. DAMAGE BY FIRE OR OTHER CASUALTY.

          a) If the  Premises  or Building  is damaged or  destroyed  by fire or
other casualty,  Tenant shall promptly notify Landlord whereupon Landlord shall,
subject to the  consent of  Landlord's  present or future  mortgagee  and to the
conditions set forth in this Section 15, repair,  rebuild or replace such damage
and restore the  Premises to  substantially  the same  condition as the Premises
were in immediately prior to such damage or destruction; provided, however, that
Landlord  shall only be obligated to restore such damage or  destruction  to the
extent of the proceeds of fire and other extended coverage  insurance  policies.
Notwithstanding  the  foregoing,  if the Premises is destroyed or damaged to the
extent that in  Landlord's  sole  judgment  the  Premises  cannot be repaired or
restored within one hundred twenty (120) days after such casualty, Landlord may,
subject to the rights of Landlord's  mortgagee,  terminate this Lease by written
notice to Tenant within ninety (90) days after the date of such casualty.

          b) The  repair,  rebuilding  or  replacement  work shall be  commenced
promptly and completed with due diligence, taking into account the time required
by Landlord to effect a settlement  with, and procure  insurance  proceeds from,
the insurer, and for delays beyond Landlord's reasonable control.

          c) The net amount of any insurance proceeds recovered by reason of the
damage or  destruction  of the Building  (meaning the gross  insurance  proceeds
excluding  proceeds received  pursuant to a rental coverage  endorsement and the
cost of adjusting the insurance  claim and  collecting  the insurance  proceeds)
shall be applied  towards the cost of restoration.  Notwithstanding  anything to
the  contrary in this Lease  Agreement,  if in  Landlord's  sole opinion the net
insurance  proceeds will not be adequate to complete such restoration,  Landlord
shall have the right to terminate  this Lease and all the unaccrued  obligations
of the parties hereto by sending a written notice of such  termination to Tenant
specifying a termination date no less than ten (10) days after its transmission;
provided,  however, that Tenant may require Landlord, except during the last two
(2) years of the Term, to withdraw the notice of  termination by agreeing to pay
the cost of  restoration  in excess of the net insurance  proceeds and by giving
Landlord  adequate  security  for such  payment  prior to the  termination  date
specified in Landlord's notice of termination. If the

                                       12
<PAGE>

net  insurance  proceeds  are more than  adequate,  the  amount by which the net
insurance  proceeds exceed the cost of restoration  will be retained by Landlord
or applied to repayment of any mortgage secured by the Premises.

          d)  Landlord's  obligation  or election to restore the Premises  under
this  Section  shall be subject to the terms of any  present or future  mortgage
affecting  the  Premises  and to the  mortgagee's  consent  if  required  in the
mortgage  and shall not,  in any  event,  include  the  repair,  restoration  or
replacement of the fixtures, improvements,  alterations,  furniture or any other
property owned, installed, made by, or in the possession of Tenant.

          e) Landlord  shall  maintain  insurance  against loss or damage to the
Building by fire and such other  casualties  as may be included  within fire and
extended  coverage  insurance  or  all-risk  insurance,  together  with a rental
coverage  endorsement  or  other  comparable  form of  coverage.  If  Tenant  is
dispossessed of the Premises due to fire or other casualty,  Tenant will receive
an abatement of its Rent during the period Tenant is dispossessed.

     16.  NON-ABATEMENT OF RENT. Except as otherwise  expressly provided in this
Lease  there  shall be no  abatement  or  reduction  of the  Fixed  Basic  Rent,
Additional  Rent or other sums payable  hereunder for any cause  whatsoever  and
this Lease shall not  terminate,  nor shall Tenant be entitled to surrender  the
Premises,  in the event of fire,  casualty  or  condemnation  or any  default by
Landlord under this Lease.

     17. INDEMNIFICATION

          a) Unless such loss,  costs or damages  were caused by  negligence  of
Landlord,  its  employees,  agents  or  contractors,  Tenant  hereby  agrees  to
indemnify,   defend  and  hold  the  Landlord  and  its  employees,  agents  and
contractors  harmless  from any loss,  costs and damages  (including  reasonable
attorney's  fees and costs)  suffered  by  Landlord,  its agents,  employees  or
contractors, as a result of any claim by a third party, its agents, employees or
contractors  arising from Tenant's occupancy of the Premises.  Tenant shall only
be liable  for  actual and direct  losses,  costs and  damages  and shall not be
liable for special,  consequential,  indirect or punitive damages.  Tenant shall
have the right to designate counsel acceptable to Landlord, such approval not be
unreasonably  withheld,  to assume the  defense of any such third party claim on
behalf of itself and Landlord.  Landlord  shall not have the right to settle any
claim without the consent of Tenant. This indemnity shall survive the expiration
or termination of this Lease.

          b) Unless such loss,  costs or damages  were caused by  negligence  of
Tenant,  its  employees,  agents  or  contractors,  Landlord  hereby  agrees  to
indemnify,  defend and hold the Tenant and its employees, agents and contractors
harmless from any loss, costs and damages (including  reasonable attorney's fees
and costs) suffered by Tenant, its agents, employees or contractors, as a result
of any claim by a third party, its agents, employees or contractors arising from
Landlord's  operation of the Premises.  Landlord shall only be liable for actual
and  direct  losses,  costs and  damages  and shall not be liable

                                       13
<PAGE>

for special,  consequential,  indirect or punitive damages.  Landlord shall have
the right to  designate  counsel  acceptable  to Tenant,  such  approval  not be
unreasonably  withheld,  to assume the  defense of any such third party claim on
behalf of itself and Tenant. Tenant shall not have the right to settle any claim
without the consent of Landlord.  This indemnity shall survive the expiration or
termination of this Lease.

          c) If Landlord  brings any action under this Lease  Agreement,  Tenant
agrees in each case to pay Landlord's reasonable attorney's fees and other costs
and expenses incurred by Landlord in connection  therewith;  provided,  however,
the Landlord prevails in such action.

     18. CONDEMNATION.

          a)  TERMINATION.  If  (i)  all  of  the  Premises  are  covered  by  a
condemnation;  or (ii) any of the Premises is covered by a condemnation  and the
remaining part is insufficient for the reasonable  operation therein of Tenant's
business;  or (iii) subject to the provisions of subsection 18(b)(i) hereof, any
of the Property is covered by a condemnation and, in Landlord's sole opinion, it
would be impractical or the  condemnation  proceeds are  insufficient to restore
the  remainder  of the  Property;  then,  in any such  event,  this Lease  shall
terminate and all  obligations  hereunder  shall cease as of the date upon which
possession is taken by the condemnor. Upon such termination the Fixed Basic Rent
and all Additional Rent herein reserved shall be apportioned and paid in full by
Tenant to  Landlord to that date and all such rent  prepaid  for periods  beyond
that date shall forthwith be repaid by Landlord to Tenant.

          b) PARTIAL CONDEMNATION.

               i) If there is a partial  condemnation  and  Landlord  decides to
terminate  pursuant  to  subsection  18(a)(iii)  hereof  then Tenant may require
Landlord,  except  during the last two (2) years of the Term,  to  withdraw  its
notice of termination by: [A] giving Landlord  written notice thereof within ten
(10) days  from  transmission  of  Landlord's  notice  to  Tenant of  Landlord's
intention to terminate, [B] agreeing to pay the cost of restoration in excess of
the  condemnation  proceeds  reduced  by those  sums  expended  by  Landlord  in
collecting the condemnation  proceeds, and [C] giving Landlord adequate security
for such payment within such ten (10) day period.

               ii) If there is a  partial  condemnation  and this  Lease has not
been  terminated  pursuant to subsection (a) hereof,  Landlord shall restore the
Building and the improvements  which are part of the Premises to a condition and
size as nearly  comparable  as  reasonably  possible to the  condition  and size
thereof  immediately  prior to the date upon  which  possession  shall have been
taken by the condemnor; provided, however, that Landlord shall only be obligated
to restore such damage from  condemnation  to the extent possible with the award
damage. If the condemnation proceeds are more than adequate to cover the cost of
restoration and the Landlord's expenses in collecting the condemnation proceeds,
any excess proceeds shall be retained by Landlord or applied to repayment of any
mortgage secured by the Premises.

                                       14
<PAGE>

               iii) If there is a partial  condemnation  and this  Lease has not
been  terminated by the date upon which the condemnor  obtains  possession,  the
obligations  of Landlord and Tenant under this Lease shall be unaffected by such
condemnation  except that there shall be an equitable  abatement for the balance
of the Term of the Fixed  Basic  Rent  according  to the  value of the  Premises
before  and after the date upon which the  condemnor  takes  possession.  In the
event that the  parties  are unable to agree upon the amount of such  abatement,
either party may submit the issue to arbitration.

          c) AWARD.  In the event of a  condemnation  affecting  Tenant,  Tenant
shall have the right to make a claim against the condemnor for removal  expenses
and moving  expenses,  loss of business  and any other  claims  Tenant may have;
provided and to the extent,  however, that such claims or payments do not reduce
the sums  otherwise  payable by the condemnor to Landlord.  Except as aforesaid,
Tenant hereby waives all claims against Landlord and against the condemnor,  and
Tenant hereby  assigns to Landlord all claims  against the condemnor  including,
without limitation,  all claims for leasehold damages and diminution in value of
Tenant's leasehold interest.

     19. QUIET ENJOYMENT.  Tenant, upon paying the Fixed Basic Rent,  Additional
Rent and other charges herein  required and observing and keeping all covenants,
agreements  and  conditions  of this  Lease,  shall  quietly  have and enjoy the
Premises during the Term without  hindrance or molestation by anyone claiming by
or through  Landlord,  subject,  however,  to the exceptions,  reservations  and
conditions of this Lease.

     20.  RULES AND  REGULATIONS.  The  Landlord  hereby  reserves  the right to
prescribe,  from  time to time,  at its sole  discretion,  reasonable  rules and
regulations  (herein  called  the "Rules and  Regulations")  attached  hereto as
Exhibit B governing  the use and  enjoyment of the Premises and the remainder of
the Property.  The Rules and Regulations shall not materially interfere with the
Tenant's use and enjoyment of the Premises in accordance  with the provisions of
this  Lease for the  Permitted  Use and shall not  increase  or modify  Tenant's
obligations  under  this  Lease.  In the event of a conflict  between  the Lease
Agreement and such rules and regulations, the Lease Agreement shall control. The
Tenant shall comply at all times with the Rules and  Regulations and shall cause
its agents, employees, invitees, visitors, and guests to do so.

     21. ASSIGNMENT AND SUBLEASE. Tenant may assign or sublease the within Lease
to any party subject to the following:

          a) In the event  Tenant  desires  to  assign  this  Lease or  sublease
seventy  percent (70%) or more of the Premises to any other party,  Tenant shall
provide  written  notice of the  terms  and  conditions  of such  assignment  or
sublease  to  Landlord  prior  to the  effective  date of any such  sublease  or
assignment,  and,  prior to such  effective  date,  the Landlord  shall have the
option, exercisable by written notice to Tenant within ten (10) business days of
Landlord's  receipt of written  notice from Tenant,  to: (i) sublease such space
from Tenant at the lower rate of (a) the rental rate per rentable square foot of
Fixed Basic Rent and Additional Rent then payable  pursuant to this Lease or (b)
the terms set

                                       15
<PAGE>

forth in the proposed sublease,  (ii) recapture (in the case of subletting) that
portion of the  Premises to be sublet or all of the  Premises (in the case of an
assignment)  ("Recapture Space") so that such prospective  subtenant or assignee
shall then become the sole Tenant of Landlord hereunder,  or (iii) recapture the
Recapture Space for Landlord's own use, whereupon Tenant shall be fully released
from any and all obligations hereunder with respect to the Recapture Space.

          b) In the event that the Landlord elects not to recapture the Lease as
hereinabove  provided,  the Tenant may nevertheless  assign this Lease or sublet
the whole or any  portion  of the  Premises,  subject  to the  Landlord's  prior
written consent not to be unreasonably withheld, conditioned or delayed , on the
basis of the following terms and conditions:

               i) The Tenant shall  provide to the Landlord the name and address
of the assignee or subtenant.

               ii)  The  assignee  or  subtenant   shall   assume,   by  written
instrument,  all of the obligations of this Lease, and a copy of such assumption
agreement  shall be  furnished  to the  Landlord  within  ten  (10)  days of its
execution. Any sublease shall expressly acknowledge that said subtenant's rights
against Landlord shall be no greater than those of Tenant.

               iii) The Tenant and each assignee  shall be and remain liable for
the observance of all the covenants and provisions of this Lease, including, but
not limited to, the payment of Fixed  Basic Rent and  Additional  Rent  reserved
herein,  through  the entire  Term of this  Lease,  as the same may be  renewed,
extended or otherwise modified.

               iv) The Tenant and any  assignee  shall  promptly pay to Landlord
fifty  percent  (50%)  of the  net  profit  received  from  such  subleasing  or
assignment.  Net profit will be calculated  after  deducting the Tenant's direct
costs of implementing the sublease or assignment.

               v) In any event,  the acceptance by the Landlord of any rent from
the  assignee or from any of the  subtenants  or the failure of the  Landlord to
insist upon a strict  performance of any of the terms,  conditions and covenants
herein  shall not release the Tenant  herein,  nor any  assignee  assuming  this
Lease, from any and all of the obligations herein during and for the entire Term
of this Lease.

               vi)  Landlord  shall  require a Five  Hundred  Dollars  ($500.00)
payment to cover its handling charges for each request for consent to any sublet
or assignment prior to its consideration of the same.  Tenant  acknowledges that
its sole remedy with respect to any assertion that Landlord's failure to consent
to any sublet or  assignment  is  unreasonable  shall be the remedy of  specific
performance  and  Tenant  shall have no other  claim or cause of action  against
Landlord as a result of Landlord's actions in refusing to consent thereto.

                                       16
<PAGE>

          c) If Tenant is a corporation  other than a corporation whose stock is
listed and traded on a nationally  recognized stock exchange,  the provisions of
subsection a hereof shall apply to a transfer (however accomplished,  whether in
a single  transaction  or in a series of related or unrelated  transactions)  of
stock (or any  other  mechanism  such as, by way of  example,  the  issuance  of
additional  stock,  a stock  voting  agreement  or change in class(es) of stock)
which  results in a change of control of Tenant as if such transfer of stock (or
other  mechanism)  which  results  in a change  of  control  of  Tenant  were an
assignment of this Lease, and if Tenant is a partnership or joint venture,  said
provisions  shall apply with respect to a transfer (by one or more transfers) of
an interest in the  distributions  of profits and losses of such  partnership or
joint venture (or other mechanism,  such as, by way of example,  the creation of
additional general partnership or limited  partnership  interests) which results
in a change  of  control  of such a  partnership  or joint  venture,  as if such
transfer  of an  interest  in the  distributions  of profits  and losses of such
partnership  or joint  venture  which  results  in a change of  control  of such
partnership or joint venture were an assignment of this Lease;  but  subsections
(a) and (b) hereof shall not apply to  transactions  with a corporation or other
entity into or with which  Tenant is merged or  consolidated  or to which all or
substantially all of Tenant's assets, stock, or membership units are transferred
or to any corporation, or other entity which controls or is controlled by Tenant
or is under  common  control  with  Tenant,  provided  that in the event of such
merger,  consolidation  or  transfer  of all or  substantially  all of  Tenant's
assets,  stock or  membership  units (i) the successor to Tenant has a net worth
computed in accordance with generally  accepted  accounting  principles at least
equal to the  greater of (1) the net worth of Tenant  immediately  prior to such
merger,  consolidation or transfer,  or (2) the net worth of Tenant herein named
on the date of this Lease,  and (ii) proof  satisfactory to Landlord of such net
worth shall have been  delivered to Landlord at least ten (10) days prior to the
effective date of any such transaction.

          d) In the event that any or all of Tenant's  interest in the  Premises
and/or this Lease is transferred  by operation of law to any trustee,  receiver,
or  other  representative  or agent  of  Tenant,  or to  Tenant  as a debtor  in
possession,  and  subsequently  any or all of Tenant's  interest in the Premises
and/or  this  Lease is  offered  or to be  offered  by  Tenant  or any  trustee,
receiver,  or other  representative  or  agent of  Tenant  as to its  estate  or
property  (such  person,  firm or entity  being  hereinafter  referred to as the
"Grantor", for assignment,  conveyance, lease, or other disposition to a person,
firm or entity other than  Landlord  (each such  transaction  being  hereinafter
referred to as a "Disposition"), it is agreed that Landlord has and shall have a
right of first refusal to purchase,  take, or otherwise  acquire,  the same upon
the same terms and  conditions  as the Grantor  thereof  shall  accept upon such
Disposition  to  such  other  person,  firm,  or  entity;  and as to  each  such
Disposition  the Grantor  shall give  written  notice to Landlord in  reasonable
detail of all of the terms and conditions of such Disposition within twenty (20)
days next following its  determination to accept the same but prior to accepting
the same, and Grantor shall not make the  Disposition  until and unless Landlord
has  failed  or  refused  to  accept  such  right  of  first  refusal  as to the
Disposition,  as set forth  herein.  Landlord  shall  have  sixty (60) days next
following its receipt of the written  notice as to such  Disposition in which to
exercise the option to acquire Tenant's  interest by such  Disposition,  and the
exercise  of the option by  Landlord  shall be effected by notice to that effect
sent to the  Grantor;  but nothing  herein  shall  require

                                       17
<PAGE>

Landlord to accept a particular  Disposition  or any  Disposition,  nor does the
rejection of any one such offer of first refusal  constitute a waiver or release
of the  obligation of the Grantor to submit other offers  hereunder to Landlord.
In the event Landlord accept such offer of first refusal,  the transaction shall
be consummated pursuant to the terms and conditions of the Disposition described
in the notice to  Landlord.  In the event  Landlord  rejects such offer of first
refusal, Grantor may consummate the Disposition with such other person, firm, or
entity;  but any  decrease in price of more than two  percent  (2%) of the price
sought from Landlord or any change in the terms of payment for such  Disposition
shall  constitute a new transaction  requiring a further option of first refusal
to be given to Landlord hereunder.

          e) Without  limiting  any of the  provisions  of this  Section  21, if
pursuant to the Federal  Bankruptcy Code (herein referred to as the "Code"),  or
any similar law hereafter  enacted  having the same general  purpose,  Tenant is
permitted to assign this Lease  notwithstanding  the  restrictions  contained in
this Lease,  adequate  assurance of future  performance by an assignee expressly
permitted  under such Code shall be deemed to mean the deposit of cash  security
in an amount  equal to the sum of one  year's  Fixed  Basic  Rent plus an amount
equal to the  Additional  Rent for the calendar year preceding the year in which
such assignment is intended to become effective,  which deposit shall be held by
Landlord for the balance of the Term, without interest, as security for the full
performance  of all of Tenant's  obligations  under this  Lease,  to be held and
applied in the manner specified for any security deposit required hereunder.

          f) Except as specifically  set forth above, no portion of the Premises
or of Tenant's  interest  in this Lease may be  acquired by any other  person or
entity, whether by assignment, mortgage, sublease, transfer, operation of law or
act of the Tenant,  nor shall Tenant pledge its interest in this Lease or in any
security deposit required hereunder.

     22. TENANT'S RELOCATION.  The Landlord, in its sole discretion,  shall have
the right  from time to time to change the  location  of the  Premises  to other
space (the "Substituted  Leased  Premises") within the Building,  subject to the
terms and conditions set forth below.

          a) The Substituted  Leased Premises shall contain a minimum floor area
of  approximately  the  same  number  of  square  feet as are  contained  in the
Premises;  and the square footage of any Common  Facilities  attributable to the
Substituted  Leased  Premises  shall  be  approximately  the same as that of the
Common Facilities attributable to the Premises.

          b) If the total square  footage  comprised by the  Substituted  Leased
Premises and its attributable Common Facilities exceed the total of the Premises
and its attributable Common Facilities,  the Tenant shall not be required to pay
any  increase  in the Fixed  Basic  Rent and  Tenant's  Percentage  shall not be
increased.  If, however, such total square footage shall be less, Tenant's Fixed
Basic Rent and Tenant's Percentage shall be decreased proportionately.

          c) The Landlord  shall give the Tenant not less than  forty-five  (45)
days prior notice of Landlord's  decision to relocate the Tenant; and the Tenant
agrees that no later than

                                       18
<PAGE>

forty-five  (45)  days  from the date of its  receipt  of such  notice  it shall
relocate to the Substituted Leased Premises.

          d) The  Landlord  shall  bear and pay for the cost and  expense of any
such relocation; provided, however, that the Tenant shall not be entitled to any
compensation  for  damages  for any  interference  with or  interruption  of its
business  during or resulting  from such  relocation.  The  Landlord  shall make
reasonable  efforts to minimize such  interference.  Tenant shall cooperate with
Landlord  so  as  to  facilitate  the  prompt  completion  by  Landlord  of  its
obligations  under  this  Section.   Without  limiting  the  generality  of  the
foregoing,  Tenant  agrees to  provide  to  Landlord  promptly  such  approvals,
instructions,  plans,  specifications  or other information as may be reasonably
requested by Landlord.

          e) In connection with any such relocation,  the Landlord shall, at its
own cost and expense,  furnish and install in (or, if practicable,  relocate to)
the Substituted Leased Premises all walls, partitions,  floors, floor coverings,
ceilings,  fixtures,  wiring and plumbing,  if any, (as distinguished from trade
fixtures,  equipment,   furniture,   furnishings  and  other  personal  property
belonging to Tenant) required for the Tenant's proper use and occupancy thereof,
all of which items shall be comparable in quality,  quantity and designto  those
situated  in  the  Premises  as  originally   constructed  by  Landlord  at  the
commencement of the Term.

          f) The payments of new Fixed Basic Rent shall  commence on the earlier
of ten (10) days after  Landlord  has  completed  the  physical  relocation  and
installation of permanent improvements in the Substituted Leased Premises or the
date that Tenant first opens for business in the Substituted Leased Premises.

          g) Landlord  and Tenant  shall  promptly  execute an amendment to this
Lease reciting the relocation of the Premises and any changes in the Fixed Basic
Rent payable hereunder.

     23.  SUBORDINATION.  This  Lease and  Tenant's  rights  hereunder  shall be
subject and  subordinate at all times in lien and priority to any first mortgage
or other  primary  encumbrance  now or hereafter  placed upon or  affecting  the
Property or the Premises,  and to any second  mortgage or  encumbrance  with the
consent  of  the  first   mortgagee,   and  to  all   renewals,   modifications,
consolidations  and  extensions  thereof,  without the  necessity of any further
instrument  or act on the part of Tenant.  Tenant shall execute and deliver upon
demand any further  instrument or instruments  confirming the  subordination  of
this  Lease to the lien of any such first  mortgage  or to the lien of any other
mortgage,  if  requested  to do so by  Landlord  with the  consent  of the first
mortgagee,  and any further  instrument or instruments of attornment that may be
desired by any such mortgagee or Landlord, provided, however, that any holder of
such  lien or  mortgage  agrees  not to  disturb  the use and  occupancy  of the
Premises  in  accordance  with  the  terms  of this  Lease  Agreement  upon  any
foreclosure.  Notwithstanding  the  foregoing,  any  mortgagee  may at any  time
subordinate  its mortgage to this Lease,  without  Tenant's  consent,  by giving
notice in writing to Tenant and  thereupon  this Lease shall be deemed  prior to
such  mortgage  without  regard  to  their  respective  dates of  execution  and
delivery.  In that event such

                                       19
<PAGE>

mortgagee  shall have the same rights with  respect to this Lease as though this
Lease had been executed  prior to the execution and delivery of the mortgage and
had been  assigned  to such  mortgagee.  Landlord  agrees  that it will use best
efforts to obtain and  deliver to Tenant a  subordination,  non-disturbance  and
attornment  agreement  from the  holder(s)  of any  mortgage  or other  security
interest affecting the Premises of Building.

     24. CURING TENANT'S DEFAULTS.  If Tenant defaults in the performance of any
of its obligations hereunder,  Landlord may, without any obligation to do so and
in addition to any other rights it may have in law or equity, elect to cure such
default  on  behalf  of  Tenant  after  written  notice  (except  in the case of
emergency) to Tenant.  Tenant shall reimburse  Landlord upon demand for any sums
paid or costs  incurred by Landlord in curing such default,  including  interest
thereon  from the  respective  dates  of  Landlord's  making  the  payments  and
incurring such costs,  which sums and costs together with interest thereon shall
be deemed Additional Rent payable within ten (10) days of demand.

     25. SURRENDER.

          a) At the  expiration or earlier  termination of the Term Tenant shall
promptly yield up the Premises and all  improvements,  alterations and additions
thereto,  and all fixtures and  equipment  servicing the Premises in a condition
which is clean of garbage and debris and broom clean and in the same  condition,
order and  repair in which they are  required  to be kept  throughout  the Term,
ordinary wear and tear excepted.

          b) If Tenant,  or any person  claiming  through  Tenant,  continues to
occupy the Premises after the  expiration or earlier  termination of the Term or
any renewal thereof without prior written consent of Landlord, the tenancy under
this Lease  shall  become,  at the option of  Landlord,  expressed  in a written
notice to Tenant and not otherwise,  either from  month-to-month or for a period
of one (1) year,  terminable by Landlord on thirty (30) days prior notice, under
the same terms and conditions set forth in this Lease; except, however, that the
Fixed Basic Rent during such continued occupancy shall be 150% of the amount set
forth in subsection 6(a). Anything to the contrary notwithstanding,  any holding
over by Tenant  without  Landlord's  prior written  consent  shall  constitute a
default  hereunder  and  shall  be  subject  to all the  remedies  set  forth in
subsection 26(b) hereof.

     26. DEFAULTS-REMEDIES.

          a) Defaults.  It shall be an event of default  under this Lease if any
one or more of the following events occurs:

               i) Tenant  fails to pay in full,  within  five (5) days of notice
from Landlord , any and all  installments of Fixed Basic Rent or Additional Rent
or any other charges or payments due and payable under this Lease whether or not
herein included as rent.

               ii) Tenant violates or fails to perform or otherwise breaches any
agreement,  term,  covenant  or  condition  contained  in this  Lease  and  such
violation or

                                       20
<PAGE>

failure  continues for a period of fifteen (15) days after notice from Landlord,
or such longer period,  not to exceed thirty (30) days,  provided such breach is
not reasonably capable of cure within fifteen (15) days and Tenant is diligently
pursuing such cure.

               iii) Tenant  becomes  insolvent or bankrupt in any sense or makes
an assignment for the benefit of creditors or if a petition in bankruptcy or for
reorganization  or for an arrangement  with creditors under any federal or state
law is filed by or against Tenant,  or a bill in equity or other  proceeding for
the appointment of a receiver or similar  official for any of Tenant's assets is
commenced,  or if any of the real or personal property of Tenant shall be levied
upon  by  any  sheriff,  marshal  or  constable;  provided,  however,  that  any
proceeding  brought  by anyone  other than the  parties to this Lease  under any
bankruptcy,  reorganization arrangement, insolvency, readjustment,  receivership
or similar law shall not  constitute an event of default until such  proceeding,
decree,  judgment  or order has  continued  unstayed  for more than  sixty  (60)
consecutive days.

          b) REMEDIES.  Upon the  occurrence  of an event of default  under this
Lease, Landlord shall have all of the following rights:

               i) Landlord may charge a late payment charge of five (5%) percent
of any amount owed to  Landlord  pursuant to this Lease which is not paid within
five (5) days of the due date  which is set forth in the Lease or, if a due date
is not specified in this Lease, within thirty (30) days of the mailing of a bill
therefor by Landlord.  If Landlord  incurs a late charge in connection  with any
payment which Tenant has failed to make within the times required in this Lease,
Tenant shall pay  Landlord,  in addition to such payment due, the full amount of
such late charge incurred by Landlord.  Nothing in this Lease shall be construed
as waiving  any rights of  Landlord  arising  out of any  default of Tenant,  by
reason of  Landlord's  imposing  or  accepting  any such late  charge(s)  and/or
interest;  the right to collect such late charge(s)  and/or interest is separate
and apart from any rights  relating to remedies  of  Landlord  after  default by
Tenant  including,  without  limitation,  the rights and  remedies  of  Landlord
provided herein.

               ii)  Landlord may  accelerate  the whole or any part of the Fixed
Basic Rent and all Additional Rent for the entire unexpired  balance of the Term
of this Lease, as well as all other charges, payments, costs and expenses herein
agreed  to be paid by  Tenant,  and  any  Fixed  Basic  Rent or  other  charges,
payments,  costs and expenses so accelerated  shall,  in addition to any and all
installments of rent already due and payable and in arrears and any other charge
or payment  herein  reserved,  included or agreed to be treated or  collected as
rent and any other  charge,  expense or cost herein  agreed to be paid by Tenant
which may be due and payable and in arrears, be deemed due and payable as if, by
the terms and provisions of this Lease, such accelerated rent and other charges,
payments, costs and expenses were on that date payable in advance.

               iii)  Landlord may  re-enter  the Premises  and, at the option of
Landlord,  remove  all  persons  and all or any  property  therefrom,  either by
summary dispossess proceedings or by any suitable action or proceeding at law or
by force or otherwise, without being liable for prosecution or damages therefor,
and Landlord may

                                       21
<PAGE>

repossess and enjoy the Premises.  Upon recovering possession of the Premises by
reason  of or based  upon or  arising  out of a default  on the part of  Tenant,
Landlord may, at Landlord's  option,  either  terminate  this Lease or make such
alterations  and repairs as may be  necessary in order to relet the Premises and
may relet the Premises or any part or parts thereof,  either in Landlord's  name
or otherwise,  for a term or terms which may, at Landlord's option, be less than
or exceed the period which would  otherwise have  constituted the balance of the
Term of this  Lease  and at such rent or rents  and upon  such  other  terms and
conditions  as in  Landlord's  sole  discretion  may seem  advisable and to such
person or  persons as may in  Landlord's  discretion  seem best;  upon each such
reletting all rents received by Landlord from such reletting shall be applied as
follows:  first,  to the payment of any costs and  expenses  of such  reletting,
including all costs of alterations  and repairs;  second,  to the payment of any
indebtedness  other than Fixed Basic Rent,  Additional Rent or other charges due
hereunder  from Tenant to Landlord;  third,  to the payment of Fixed Basic Rent,
Additional Rent and other charges due and unpaid hereunder;  and the residue, if
any,  shall be held by Landlord  and applied in payment of future rent as it may
become due and payable hereunder.  If rentals received from reletting during any
month are less than that to be paid  during that month by Tenant,  Tenant  shall
pay any such  deficiency to Landlord.  Such  deficiency  shall be calculated and
paid  monthly.  No such  re-entry or taking  possession  of the  Premises or the
making of alterations or improvements  thereto or the reletting thereof shall be
construed as an election on the part of Landlord to terminate  this Lease unless
written notice of termination is given to Tenant.  Landlord shall in no event be
liable in any way  whatsoever for failure to relet the Premises or, in the event
that the Premises or any part or parts thereof are relet, for failure to collect
the rent  thereof  under  such  reletting.  Notwithstanding  any such  reletting
without termination, Landlord may at any time thereafter elect to terminate this
Lease for such previous breach.

               iv)  Landlord may  terminate  this Lease and the Term without any
right on the part of Tenant to waive the forfeiture by payment of any sum due or
by other  performance  of any  condition,  term or  covenant  broken.  Upon such
termination,  Landlord shall be entitled to recover,  in addition to any and all
sums and damages for violation of Tenant's obligations hereunder in existence at
the time of such termination, damages for Tenant's default in an amount equal to
the amount of the Fixed Basic Rent and Additional  Rent reserved for the balance
of the Term, as well as all other charges,  payments,  costs and expenses herein
agreed to be paid by Tenant all of which  amount  shall be  immediately  due and
payable from Tenant to Landlord upon demand therefor.

               v) WHEN  THIS  LEASE  AND THE TERM OR ANY  EXTENSION  OR  RENEWAL
THEREOF SHALL HAVE BEEN TERMINATED ON ACCOUNT OF ANY DEFAULT BY TENANT,  OR WHEN
THE TERM HAS  EXPIRED,  UPON FIVE (5)  BUSINESS  DAYS  PRIOR  WRITTEN  NOTICE TO
TENANT,  IT SHALL BE LAWFUL FOR ANY ATTORNEY OF ANY COURT OF RECORD TO APPEAR AS
ATTORNEY  FOR TENANT AS WELL AS FOR ALL PERSONS  CLAIMING  BY,  THROUGH OR UNDER
TENANT,  AND TO FILE AN AGREEMENT FOR ENTERING IN ANY COMPETENT  COURT AN ACTION
FOR JUDGMENT IN EJECTMENT AGAINST TENANT AND ALL PERSONS CLAIMING

                                       22
<PAGE>

BY,  THROUGH OR UNDER TENANT FOR THE RECOVERY BY LANDLORD OF  POSSESSION  OF THE
PREMISES,  FOR WHICH THIS LEASE SHALL BE A  SUFFICIENT  WARRANT;  WHEREUPON,  IF
LANDLORD SO DESIRES,  AN  APPROPRIATE  WRIT OF POSSESSION  MAY ISSUE  FORTHWITH,
WITHOUT ANY PRIOR WRIT OR  PROCEEDING  WHATSOEVER,  AND PROVIDED THAT IS FOR ANY
REASON AFTER SUCH ACTION SHALL HAVE BEEN  COMMENCED IT SHALL BE  DETERMINED  AND
POSSESSION OF THE PREMISES  REMAIN IN OR BE RESTORED TO TENANT,  LANDLORD  SHALL
HAVE THE RIGHT FOR THE SAME DEFAULT AND UPON ANY SUBSEQUENT DEFAULT OR DEFAULTS,
OR UPON THE  TERMINATION  OF THIS  LEASE OR  TENANT'S  RIGHT  OF  POSSESSION  AS
HEREINBEFORE  SET FORTH,  TO BRING ONE OR MORE  FURTHER  ACTIONS IN EJECTMENT AS
HEREINBEFORE SET FORTH TO CONFESS JUDGMENT FOR THE RECOVERY OF POSSESSION OF THE
PREMISES.

          c) WAIVER OF JURY TRIAL. IT IS MUTUALLY AGREED BY AND BETWEEN LANDLORD
AND TENANT THAT (A) THEY HEREBY WAIVE TRIAL BY JURY IN ANY ACTION, PROCEEDING OR
COUNTER-CLAIM  BROUGHT BY EITHER OF THE PARTIES  HERETO AGAINST THE OTHER ON ANY
MATTER  WHATSOEVER  ARISING OUT OF OR IN ANY WAY CONNECTED WITH THIS LEASE,  THE
RELATIONSHIP  OF LANDLORD AND TENANT,  TENANT'S USE OF OCCUPANCY OF THE PREMISES
OR CLAIM OF INJURY OR DAMAGE,  AND (B) IN ANY ACTION AGAINST LANDLORD BY TENANT,
THE LEGAL FEES OF THE  PREVAILING  PARTY WILL BE PAID BY THE OTHER  PARTY TO THE
ACTION.

          d) NON-WAIVER. No waiver by Landlord of any breach by Tenant of any of
Tenant's  obligations,  agreements or covenants  herein shall be a waiver of any
subsequent breach or of any other obligation,  agreement or covenant,  nor shall
any  forbearance by Landlord to seek a remedy for any event of default by Tenant
be a waiver by Landlord of any rights and  remedies  with respect to such or any
subsequent event of default.

          e) RIGHTS AND REMEDIES CUMULATIVE. No right or remedy herein conferred
upon or reserved to Landlord is intended to be  exclusive  of any other right or
remedy  provided  herein or by law, but each shall be cumulative and in addition
to every other right or remedy given herein or now or hereafter  existing at law
or in equity or by statute.

     27.  CONDITION  OF  PREMISES.  Tenant's  occupancy  of the  Premises  shall
constitute  acceptance of the Work performed by Landlord  pursuant to Section 3,
subject to any punchlist  items agreed to by the parties within thirty (30) days
after the Commencement Date and any latent or structural defects in the Premises
constructed in accordance with the Plans.


                                       23
<PAGE>

     28. HAZARDOUS SUBSTANCES.

          a)  Landlord  and  Tenant  shall not  cause or allow  the  generation,
treatment,  storage or disposal of Hazardous  Substances on or near the Premises
or Property.  "Hazardous  Substances" shall mean (i) any hazardous  substance as
that term is defined in the Comprehensive  Environmental Response,  Compensation
and  Liability Act  ("CERCLA"),  42 U.S.C.  9601 et seq.,  as amended,  (ii) any
hazardous waste or hazardous  substance as those terms are defined in any local,
state or Federal law,  regulation or ordinance not  inapplicable to the Premises
and Property, or (iii) petroleum including crude oil or any fraction thereof. In
the event Landlord or Tenant uses any Hazardous  Substances,  Landlord or Tenant
shall  dispose of such  substances in accordance  with all  applicable  Federal,
state and local laws, regulations and ordinances.

          b) Landlord and Tenant agree to  indemnify,  defend and hold  harmless
the other, its employees,  agents, successors, and assigns, from and against any
and all damage, claim,  liability,  or loss, including reasonable attorneys' and
other fees, arising out of or in any way connected to the generation, treatment,
storage  or  disposal  of  Hazardous  Substances  by  Landlord  or  Tenant,  its
employees,  agents,  contractors,  or  invitees,  on or  near  the  Premises  or
Property.  Such duty of  indemnification  shall  include,  but not be limited to
damage,   liability,   or  loss  pursuant  to  all  Federal,   state  and  local
environmental laws, rules and ordinances, strict liability and common law.

          c) Landlord and Tenant agree to notify each other  immediately  of any
disposal of Hazardous  Substances in the Premises or Property,  of any discovery
of Hazardous  Substances  in the  Premises,  or of any notice by a  governmental
authority or private party  alleging or suggesting  that a disposal of Hazardous
Substances on or near the Premises or Property may have  occurred.  Furthermore,
Landlord and Tenant agree to provide the other with full and complete  access to
any  documents  or  information  in its  possession  or control  relevant to the
question  of the  generation,  treatment,  storage,  or  disposal  of  Hazardous
Substances on or near the Premises.

          d) Except as disclosed in that certain  Phase 1 -  Environmental  Site
Assessment of the Solarex/Peco  Energy Facility,  Newtown,  PA, Job No. OPG97001
prepared by OXFORD  Engineers &  Consultants,  Inc,  dated May,  1997,  Landlord
represents  and  warrants  that,  to the  best of its  knowledge,  there  are no
Hazardous Substances in, under or about the Property. Landlord acknowledges that
Tenant and its employees, agents, successors and assigns shall not be liable for
any claims,  costs,  damages or liabilities  associated  with the  environmental
conditions  existing at the Property as of the Commencement Date as disclosed in
the foregoing Phase 1 Environmental  Site Assessment  unless such conditions are
exacerbated by the Tenant, its employees, agents, successors or assigns.

     29.  RECORDING.  Neither this Lease nor a memorandum of this Lease shall be
recorded in any public records without the written consent of Landlord.

     30. BROKERS'  COMMISSION.  Tenant  represents and warrants to Landlord that
the

                                       24
<PAGE>

Brokers (as defined in the  Preamble)  are the sole brokers with whom Tenant has
negotiated in bringing  about this Lease and Tenant agrees to indemnify and hold
Landlord and its mortgagee(s)  harmless from any and all claims of other brokers
and expenses in connection  therewith  arising out of or in connection  with the
negotiation of or the entering into this Lease by Landlord and Tenant.  Provided
the transactions contemplated hereby are consummated, Landlord shall pay Brokers
a commission in  accordance  with a written  agreement  between such Brokers and
Landlord.  In no event shall Landlord's  mortgagee(s) have any obligation to any
broker involved in this transaction. In the event that no broker was involved as
aforesaid,  then Tenant  represents  and warrants to the Landlord that no broker
brought about this transaction, and Tenant agrees to indemnify and hold Landlord
harmless  from any and all claims of any broker  arising out of or in connection
with the  negotiations  of,  or  entering  into of,  this  Lease by  Tenant  and
Landlord.

     31. NOTICES. All notices, demands, requests,  consents,  certificates,  and
waivers required or permitted  hereunder from either party to the other shall be
in writing and sent by United States certified mail,  return receipt  requested,
postage prepaid, or by recognized overnight courier, addressed as follows:

                  If to Tenant:

                  Bio-Imaging Technologies, Inc.

                  Atten:  Mark L. Weinstein,
                          Chief Executive Officer

                  with a copy to:

                  Buchanan Ingersoll, Professional Corporation
                  500 College Road East
                  Princeton, NJ  08540
                  Atten:  Stuart B. Dember, Esquire

                  If to Landlord:

                  Yardley Road Associates, L.P.
                  c/o O'Neill Properties Group, L.P.
                  1101 West DeKalb Pike, Suite 200
                  Wayne, PA  19087
                  Attn:  President

                  with a copy to:

                  Kevin W. Walsh, Esquire
                  Adelman Lavine Gold and Levin
                  1101 West DeKalb Pike, Suite 201
                  Philadelphia, PA 19102-1799

                                       25
<PAGE>

Either party may at any time, in the manner set forth for giving  notices to the
other,  specify a different  address to which notices to it shall  thereafter be
sent.

     32.  IRREVOCABLE  OFFER: NO OPTION.  This Lease shall become effective only
upon  execution  thereof by J. Brian  O'Neill,  or other  authorized  officer of
Landlord and by an authorized officer of Tenant.

     33.  INABILITY  TO  PERFORM.  If  Landlord  is  delayed or  prevented  from
performing any of its  obligations  under this Lease by reason of strike,  labor
troubles,  or any cause whatsoever beyond Landlord's control, the period of such
delay or such  prevention  shall be deemed added to the time herein provided for
the  performance  of any such  obligation  by Landlord.  The  provisions of this
Section 33 shall not delay the Outside Date.

     34. SURVIVAL.  Notwithstanding  anything to the contrary  contained in this
Lease,  the  expiration  of the Term of this Lease,  whether by lapse of time or
otherwise,   shall  not  relieve  Tenant  or  Landlord  from  their   respective
obligations accruing prior to the expiration of the Term.

     35. CORPORATE TENANTS. If Tenant is a corporation,  the person(s) executing
this Lease on behalf of Tenant hereby covenant(s) and warrant(s) that: Tenant is
a duly  formed  corporation  qualified  to do business in the state in which the
Property is located;  Tenant will remain  qualified to do business in said state
throughout  the  Term  and any  renewals  thereof;  and  such  persons  are duly
authorized  by such  corporation  to execute and deliver this Lease on behalf of
the corporation.

     36. TENANT REPRESENTATIONS AND WARRANTIES. [Intentionally Deleted].

     37. WAIVER OF INVALIDITY OF LEASE. Each party agrees that it will not raise
or assert as a defense to any obligation  under the Lease or make any claim that
the Lease is invalid or  unenforceable  due to any  failure of this  document to
comply with ministerial requirements including, without limitation, requirements
for corporate  seals,  attestations,  witnesses,  notarizations or other similar
requirements  and each party hereby waives the right to assert any such defenses
or make any claim of invalidity or unenforceability due to any of the foregoing.

     38. SECURITY  DEPOSIT.  As security for the full and prompt  performance by
Tenant of the terms and  covenants  of this  Lease,  Tenant has  deposited  with
Landlord  the  Security  Deposit,  as set forth in the  Preamble.  The  Security
Deposit shall not  constitute  rent for any month (unless so applied by Landlord
on account of Tenant's default  hereunder).  Tenant shall, upon demand,  restore
any portion of the Security Deposit which may be applied by Landlord to cure any
default by Tenant  hereunder.  To the extent that  Landlord  has not applied the
Security  Deposit or any portion  thereof on account of a default,  the Security
Deposit, or such remaining portion of the Security Deposit, shall be returned to
Tenant, without interest, promptly following the termination of this Lease.

                                       26
<PAGE>

     39. Estoppel Certificate.

          a) Each of Landlord and Tenant shall from time to time, within fifteen
(15) days after request,  execute,  acknowledge and deliver to the other party a
written instrument in recordable form, substantially in the form attached hereto
as Exhibit E (a "Estoppel  Certificate"),  certifying  (i) that this Lease is in
full force and effect and has not been modified, supplemented or amended (or, if
there have been  modifications,  supplements or  amendments,  that it is in full
force and  effect  as  modified,  supplemented  or  amended,  and  stating  such
modifications,  supplements and amendments); (ii) the dates to which Fixed Basic
Rent and Additional Rent and any other charges arising hereunder have been paid;
(iii) the amount of any prepaid  rents or credits due  Tenant,  if any;  (iv) if
applicable,  that Tenant has accepted  possession and has entered into occupancy
of the Premises,  and certifying the Commencement Date and the Termination Date;
(v) whether or not, to the best of such party's knowledge,  all conditions under
the Lease to be performed by the other party prior  thereto have been  satisfied
and  whether  or not such party is then in  default  in the  performance  of any
covenant, agreement or condition contained in this Lease and specifying each, if
any,  unsatisfied  condition and each,  if any,  default of which such party may
have knowledge;  and (vi) any other fact or condition  related to the Lease, the
Tenant or Landlord reasonably requested. Any certification delivered pursuant to
the  provisions of this Article shall be intended to be relied upon by Landlord,
Tenant and any mortgagee or  prospective  mortgagee or purchaser of the Property
or  of  any  interest  therein.   Notwithstanding  the  foregoing,  Tenant's  or
Landlord's  failure to furnish a Estoppel  Certificate  within said fifteen (15)
day period shall constitute a default under this Lease.

     40. RIGHTS RESERVED BY LANDLORD.  Landlord  waives no rights,  except those
that may be specifically  waived herein, and explicitly retains all other rights
including,  without limitation, the following rights, each of which Landlord may
exercise without notice to Tenant and without  liability to Tenant for damage or
injury to property,  person or business on account of the exercise thereof,  and
the exercise of any such rights shall not be deemed to constitute an eviction or
disturbance  of Tenant's  use or  possession  of the Premises and shall not give
rise to any claim for set-off or abatement of Rent or any other claim:

          a) To change the name or street address of the Building.

          b) To install,  affix and  maintain  any and all signs on the exterior
and on the interior of the Building.

          c)  To  decorate  or  to  make  repairs,  alterations,  additions,  or
improvements, whether structural or otherwise, in and about the Building, or any
part  thereof,  and for such  purposes to enter upon the Premises and during the
continuance of any of such work, to temporarily close doors,  entry ways, public
space and  corridors in the Building  and to  interrupt or  temporarily  suspend
services or use of facilities, all without affecting any of Tenant's obligations
hereunder,  so long as the  Premises  are  reasonably  accessible  and  Tenant's
conduct of its business is not unreasonably interfered with.

                                       27
<PAGE>

          d) To furnish  door keys for the entry  door(s) in the Premises on the
Commencement  Date  and to  retain  at  all  times,  and  to use in  appropriate
instances,  keys to all doors  within and into the  Premises.  Tenant  agrees to
purchase only from Landlord additional duplicate keys as required,  to change no
locks,  and not to affix locks on doors without the prior written consent of the
Landlord.  Upon the  expiration  of the Term or  Tenant's  right to  possession,
Tenant  shall  return all keys to Landlord  and shall  disclose to Landlord  the
combination of any safes, cabinets or vaults left in the Premises.

          e) To designate and approve all window coverings used in the Building.

          f) To approve the weight, size and location of safes, vaults and other
heavy  equipment  and  articles in and about the Premises and the Building so as
not to exceed  the legal  load per  square  foot  designated  by the  structural
engineers  for the  Building,  and to require all such items and  furniture  and
similar  items to be moved into or out of the Building and Premises only at such
times and in such manner as Landlord  shall direct in writing.  Tenant shall not
install or operate machinery or any mechanical  devices of a nature not directly
related to  Tenant's  ordinary  use,  as limited by the  Permitted  Use,  of the
Premises without the prior written consent of Landlord. The movement of Tenant's
property into or out of the Building or the Premises and within the Building are
entirely at the risk and  responsibility  of Tenant,  and Landlord  reserves the
right  to  require  written  authorization  from  Tenant,  in form  and  content
satisfactory  to Landlord,  before allowing any property to be moved into or out
of the Building or Premises.

          g) To  regulate  delivery  of  supplies  and the usage of the  loading
docks, receiving areas and freight elevators.

          h) To enter the  Premises  in  accordance  with  Section  14,  and, if
vacated  or  abandoned,  to show the  Premises  at any time and to  prepare  the
Premises for re-occupancy.

          i) To erect, use and maintain pipes, ducts,  wiring and conduits,  and
appurtenances  thereto, in and through the Premises provided Tenant's conduct of
its business is not unreasonably interfered with.

          j) To grant to any person or to  reserve  unto  itself  the  exclusive
right to conduct any business or render any service in the Building. If Landlord
elects to make available to tenants in the Building any services or supplies, or
arranges a master contract  therefor,  Tenant agrees to obtain its requirements,
if any,  therefor  from Landlord or under any such  contract,  provided that the
charges therefor are reasonably consistent with market rates.

          k) To alter the  layout,  design  and/or use of the  Building  in such
manner as Landlord,  in its sole discretion,  deems appropriate,  so long as the
character  of the Building as a first class office  building is  maintained  and
provided Tenant's conduct of its business is not unreasonably interfered with.


                                       28
<PAGE>

     41. MISCELLANEOUS.

          a) ENTIRE  AGREEMENT.  This  Lease  represents  the  entire  agreement
between the parties  hereto and there are no  collateral  or oral  agreements or
understandings  between  Landlord and Tenant with respect to the Premises or the
Property.  No rights,  easements or licenses are acquired in the Property or any
land adjacent to the Property by Tenant by  implication  or otherwise  except as
expressly set forth in the provisions of this Lease.

          b) MODIFICATION. This Lease shall not be modified in any manner except
by an instrument in writing executed by the parties. In addition,  Tenant agrees
to make such  changes to this Lease as are required by any  mortgagee,  provided
such  changes  do  not  substantially  affect  Tenant's  rights  and  obligation
hereunder.

          c) INTERPRETATION. The masculine (or neuter) pronoun, singular number,
shall include the  masculine,  feminine and neuter  genders and the singular and
plural number.

          d) EXHIBITS. Each writing or plan referred to herein as being attached
as an Exhibit or otherwise designated herein as an Exhibit hereto is hereby made
a part hereof.

          e) CAPTIONS  AND  HEADINGS.  The  captions  and  headings of sections,
subsections and the table of contents  herein are for  convenience  only and are
not  intended to indicate  all of the subject  matter in the text and they shall
not be deemed to limit, construe,  affect or alter the meaning of any provisions
of this Lease and are not to be used in interpreting this Lease or for any other
purpose in the event of any controversy.

          f) INTEREST.  Wherever interest is required to be paid hereunder, such
interest shall be at the highest rate  permitted  under law but not in excess of
twelve percent (12%).

          g)  SEVERABILITY.  If any  term or  provision  of this  Lease,  or the
application  thereof to any person or  circumstance  shall,  to any  extent,  be
invalid or  unenforceable,  the remainder of this Lease,  or the  application of
such term or provision to persons or circumstances  other than those as to which
it is held invalid or  unenforceable,  shall not be affected  thereby,  and each
term and  provision  of this Lease shall be valid and be enforced to the fullest
extent permitted by law.

          h)  JOINT  AND  SEVERAL   LIABILITY.   If  two  or  more  individuals,
corporations,  partnerships  or other persons (or any combination of two or more
thereof) shall sign this Lease as Tenant, the liability of each such individual,
corporation,  partnership or other persons to pay the Rent and perform all other
obligations  hereunder shall be deemed to be joint and several, and all notices,
payments  and  agreements  given  or  made  by,  with  or to  any  one  of  such
individuals, corporations, partnerships or other persons shall be deemed

                                       29
<PAGE>

to have been given or made by, with or to all of them. In like manner, if Tenant
shall be a  partnership  or other  legal  entity,  the  members of which are, by
virtue of any applicable law or regulation,  subject to personal liability,  the
liability of each such member shall be joint and several.

          i) NO REPRESENTATIONS BY LANDLORD. Landlord and Landlord's agents have
made no representations,  agreements, conditions, warranties,  understandings or
promises, either oral or written, other than as expressly set forth herein, with
respect to this Lease, the Premises and/or the Building.

          j)  RELATIONSHIP   OF  PARTIES.   This  Lease  shall  not  create  any
relationship between the parties other than that of Landlord and Tenant.

          k) CHOICE OF LAW. The terms of this Lease shall be construed under the
laws of the  Commonwealth of Pennsylvania,  and that exclusive  jurisdiction and
venue shall be in the Court of Common  Pleas of the County in which the Property
is located.

     42. ADDITIONAL DEFINITIONS.

          a) "Date of this Lease" or "date of this Lease" shall mean the date of
acceptance  of this Lease by the  Landlord,  following  execution  and  delivery
thereof  to  Landlord  by Tenant and that date  shall be  inserted  in the space
provided in the Preamble.

          b) "Landlord" as used herein includes the Landlord named above as well
as its  successors  and  assigns,  each of whom  shall  have  the  same  rights,
remedies,  powers, authorities and privileges as it would have had it originally
signed this lease as  Landlord.  Any such person,  whether or not named  herein,
shall have no liability  hereunder  after ceasing to hold title to the Premises.
Neither  Landlord nor any principal of Landlord nor any owner of the Building or
the Lot,  whether  disclosed or undisclosed,  shall have any personal  liability
with  respect to any of the  provisions  of this Lease or the  Premises,  and if
Landlord is in breach or default with respect to  Landlord's  obligations  under
this Lease or  otherwise,  Tenant shall look solely to the equity of Landlord in
the Property for the satisfaction of Tenant's remedies.

          c) "Tenant" as used herein  includes the Tenant named above as well as
its  heirs,  successors  and  assigns,  each of which  shall  be under  the same
obligations,  liabilities and disabilities and each of which shall have the same
rights,  privileges  and powers as it would  have  possessed  had it  originally
signed this Lease as Tenant.  Each and every  person named above as Tenant shall
be bound formally and severally by the terms, covenants and agreements contained
herein. However, no such rights, privileges or powers shall inure to the benefit
of any assignee of Tenant,  immediate or remote,  unless the  assignment to such
assignee is  permitted or has been  approved in writing by Landlord.  Any notice
required or  permitted  by the terms of this Lease may be given by or to any one
of the persons  named above as Tenant,  and shall have the same force and effect
as if given by or to all of them.

                                       30
<PAGE>

          d)  "Mortgage"  and  "Mortgagee"  as used herein  includes any lien or
encumbrance  on the Premises or the Property or on any part of or interest in or
appurtenance to any of the foregoing,  including  without  limitation any ground
rent or ground lease if  Landlord's  interest is or becomes a leasehold  estate.
The word  "mortgagee"  is used  herein to include  the  holder of any  mortgage,
including any ground  Landlord if Landlord's  interest is or becomes a leasehold
estate. Wherever any right is given to a mortgagee,  that right may be exercised
on behalf of such  mortgagee by any  representative  or servicing  agent of such
mortgagee.

          e) "Person" as used herein includes a natural person, a partnership, a
corporation,  an  association,  and any other form of  business  association  or
entity.

          f)  "Property"  as used herein  shall mean the  Building  and the lot,
tract or parcel of land on which the Building is situated.

          g) "Rent" or "rent" as used herein shall mean all Fixed Basic Rent and
Additional Rent reserved under this Lease.

     43.  TENANT'S RIGHT OF FIRST OFFER.

          a) Tenant  shall have a right of first offer  ("Right of Offer")  with
respect to the  leasing  of any space in the  Building  ("Offer  Space") as such
space becomes available for leasing by the Landlord,  provided that there is not
an event of default  continuing in accordance  with the terms and  conditions of
the Lease,  Tenant is in possession  of the Premises  pursuant to this Lease and
subject to the following conditions:

               i)  Landlord  shall  offer such Offer  Space to Tenant in writing
(the  "Landlord  Notification")  on the terms set  forth in  Section  43(a)(ii),
before entering into a lease with another tenant for the Offer Space. Tenant may
accept the Offer Space only by  delivering  to Landlord  written  notice of such
acceptance  of the  entire  Offer  Space  within ten (10)  Business  Days of the
Landlord Notification. If Tenant fails to accept the Offer Space within such ten
(10) Business Day period,  Tenant will be deemed to have irrevocably  waived its
Right of Offer for that  particular  Offer Space and  Landlord  may enter into a
lease for the Offer  Space at any rental rate  (within ten percent  (10%) of the
rental rate offered to Tenant) with other persons or entities. If Landlord fails
to lease the Offer Space  within  ninety  (90) days,  then it must be offered to
Tenant again in  accordance  with this Section 43.  Tenant must accept the Offer
Space offered  pursuant to this provision in whole and not in part.  Once Tenant
exercises its Right of Offer with respect to the Offer Space,  the exercise will
be irrevocable.

               ii) All of the terms and  conditions  of this Lease will apply to
any Offer Space leased by Tenant, effective as of the date of delivery to Tenant
of such Offer Space. The term of the lease with respect to the Offer Space shall
be  coterminous  with the Term  applicable to the original  Premises.  The Fixed
Basic Rent rate for the Offer  Space  will be the Fixed  Basic Rent set forth in
the Landlord Notification and


                                       31
<PAGE>

Tenant's  Proportionate  Share shall be  increased in  proportion  to the square
footage of any Offer Space leased by Tenant.

          b)  Landlord  will have no  liability  to Tenant if any  Tenant of the
Offer Space  wrongfully  holds over. In the event such Tenant  wrongfully  holds
over,  Landlord  will  attempt in good faith to cause such  Tenant to vacate the
Offer Space.

     SECTION  26(b) HEREOF SETS FORTH A WARRANT OR AUTHORITY  FOR AS ATTORNEY TO
CONFESS  JUDGMENT FOR  EJECTMENT  AGAINST  TENANT.  IN GRANTING  THIS WARRANT OF
ATTORNEY  TO  CONFESS   JUDGMENT  AGAINST  TENANT,   TENANT  HEREBY   KNOWINGLY,
INTENTIONALLY  AND  VOLUNTARILY,  AND (ON THE ADVICE OF THE SEPARATE  COUNSEL OF
TENANT,  IF TENANT  HAS USED  COUNSEL  IN REGARD TO  ENTERING  INTO THIS  LEASE)
UNCONDITIONALLY WAIVES ANY AND ALL RIGHTS TENANT HAS OR MAY HAVE TO PRIOR NOTICE
AND AN OPPORTUNITY  FOR HEARING UNDER THE  CONSTITUTIONS  AND LAWS OF THE UNITED
STATES AND THE COMMONWEALTH OF PENNSYLVANIA.

     IN WITNESS  WHEREOF,  and in  consideration  of the mutual  entry into this
Lease and for other good and valuable consideration, and intending to be legally
bound,  each party hereto has caused this  agreement to be duly  executed  under
seal.

Landlord:
- ---------

Date Signed: 10/1/99                        YARDLEY ROAD ASSOCIATES, L.P.
             -------                        By:  YARDLEY ROAD ASSOCIATES
                                                 ACQUISITION CORPORATION

                                            By: /s/Stephen Starden
                                                --------------------------
                                                Name:  Stephen Starden
                                                Title: Vice President
                                            Attest: /s/John P. Jade
                                                    ----------------------
Tenant:

Date Signed: 9/22/99                        BIO-IMAGING TECHNOLOGIES, INC.
             -------

                                            By: /s/Mark L. Weinstein
                                                ------------------------
                                                Name: Mark L. Weinstein
                                                      ------------------
                                                Title:President & CEO
                                                      ------------------
                                            Attest: /s/ Robert J. Phillips
                                                    ----------------------
                                                Title: Vice President, Chief
                                                       Financial Officer
                                                       ---------------------

                                       32
<PAGE>

                                     RIDER A


RENEWAL  OPTION:  Tenant is hereby  granted  two (2) options to renew this Lease
- ---------------
upon the following terms and conditions:

At the time of the  exercise  of each  option  to renew  and at the time of each
renewal,  Tenant  shall  not be in  default  in  accordance  with the  terms and
provisions of this Lease, and shall be in possession of the Premises pursuant to
this Lease.

Notice of the exercise of the option shall be sent to the Landlord in writing at
least six (6) months but not more than twelve (12) months before the  expiration
of the term of this Lease.

Each  renewal  term shall be for a period of five (5) years,  to commence at the
expiration  of the Term of this  Lease or the  expiration  of the first  renewal
term, as applicable,  and all of the terms and  conditions of this Lease,  other
than the Fixed Basic Rent, shall apply during any such renewal term.

The annual  fixed  basic rent to be paid during the each  renewal  term shall be
ninety  five  percent  (95%) of the fair  rental  value per  square  foot of the
Premises at the  commencement  of each renewal  term.  In  determining  the fair
rental  value,  the  Landlord  shall  notify  Tenant of the fair rental value as
established by Landlord.  Should Tenant dispute Landlord's  determination,  then
the Tenant shall be free to, at the Tenant's  sole cost and expense,  employ the
services of an  appraiser  familiar  with office  buildings  located  within the
Newtown,  Bucks County,  Pennsylvania area comparable to the Building, who shall
be a member of MAI and who shall  render an  appraisal.  If the Landlord and the
Tenant's appraiser cannot agree on the fair rental value, or in such case, on an
independent  appraiser acceptable to both, either party may request the American
Arbitration  Association  to appoint such  independent  appraiser who shall be a
member of MAI  familiar  with office  buildings  in the area of the Building who
shall render an  appraisal,  and in such event the judgment of a majority of the
three appraisers shall be final and binding upon the parties.  The parties shall
share equally in the cost of any such independent appraiser.  Pending resolution
of the issue of fair  rental  value,  the Tenant  shall pay the  Landlord  as of
commencement  of the  renewal  term,  the Fixed  Basic  Rent as  established  by
Landlord,  subject to retroactive  adjustment upon final  determination  of this
issue.




<PAGE>


                                    EXHIBIT A


                              LOCATION OF PREMISES

<PAGE>



                                   EXHIBIT A-1
                                   -----------


                              OFFICE BUILDING AREA




<PAGE>



                                    EXHIBIT B
                                    ---------

                              RULES AND REGULATIONS


1.  OBSTRUCTION OF  PASSAGEWAYS:  The  sidewalks,  entrance,  passages,  courts,
    ---------------------------
elevators,  vestibules,  stairways,  corridors  and public parts of the Building
shall not be  obstructed  or  encumbered  by  Tenant  or used by Tenant  for any
purpose  other than  ingress and egress.  If the  Premises  are  situated on the
ground  floor  with  direct  access  to the  street,  then  Landlord  shall,  at
Landlord's  expense,  keep the  sidewalks  and  curbs  directly  in front of the
Premises clean and free from ice, snow and refuse.

2.  WINDOWS:  Windows in the  Premises  shall not be covered  or  obstructed  by
    -------
Tenant.  No  bottles,  parcels or other  articles  shall be placed on the window
sills,  in the  halls,  or in any  other  part of the  Building  other  than the
Premises.  No  article  shall  be  thrown  out of the  doors or  windows  of the
Premises.

3.  PROJECTIONS  FROM BUILDING:  No awnings,  air-conditioning  units,  or other
    --------------------------
fixtures  shall be  attached  to the  outside  walls or the window  sills of the
Building or otherwise affixed so as to project from the Building,  without prior
written consent of Landlord.

4.  SIGNS:  No sign or  lettering  shall be affixed by Tenant to any part of the
    -----
outside of the  Premises,  or any part of the inside of the Premises so as to be
clearly  visible  from the outside of the  Premises,  without the prior  written
consent of Landlord.  However,  Tenant shall have the right to place its name on
any door  leading  into the  Premises  the size,  color and style  thereof to be
subject  to the  Landlord's  approval.  Tenant  shall not have the right to have
additional  names  placed on the Building  directory  without  Landlord's  prior
written consent.

5. FLOOR COVERING: Tenant shall not lay linoleum or other similar floor covering
   --------------
so that the same shall come in direct contact with the floor of the Premises. If
linoleum or other similar floor  covering is desired to be used, an  interlining
of  builder's  deadening  felt  shall  first be fixed to the floor by a paste or
other material that may easily be removed with water, the use of cement or other
similar adhesive material being expressly prohibited.

6. INTERFERENCE WITH OCCUPANTS OF BUILDING:  Tenant shall not make, or permit to
   ---------------------------------------
be made, any unseemly or disturbing noises or odors and shall not interfere with
other  tenants  or  those  having  business  with  them.  Tenant  will  keep all
mechanical  apparatus in the Premises  free of vibration  and noise which may be
transmitted beyond the limits of the Premises.

7. LOCK KEYS: No additional locks or bolts of any kind shall be placed on any of
   ---------
the doors or windows by Tenant.  Tenant shall,  on the  termination  of Tenant's
tenancy,  deliver to Landlord all keys to any space  within the Building  either
furnished  to or otherwise


<PAGE>

procured by Tenant,  and in the event of the loss of any keys furnished,  Tenant
shall pay to Landlord the cost thereof.  Tenant,  before closing and leaving the
Premises,  shall ensure that all windows are closed and entrance  doors  locked.
Nothing in this Paragraph 7 shall be deemed to prohibit Tenant from installing a
burglar  alarm within the  Premises,  provided:  (1) Tenant  obtains  Landlord's
consent which will not be unreasonably  withheld or delayed; (2) Tenant supplies
Landlord  with copies of the plans and  specifications  of the system;  (3) such
installation  shall not damage the Building;  and (4) all costs of  installation
shall be borne solely by Tenant.

8.  CONTRACTORS:  No  contract of any kind with any  supplier of towels,  water,
    -----------
toilet  articles,  waxing,  rug  shampooing,  venetian blind washing,  furniture
polishing,  lamp servicing,  cleaning of electrical  fixtures,  removal of waste
paper, rubbish,  garbage, or other like service shall be entered into by Tenant,
nor shall any  machine of any kind be  installed  in the  Building or the Office
Building  Area without the prior written  consent of the Landlord.  Tenant shall
not employ  any  persons  other  than  Landlord's  janitors  for the  purpose of
cleaning the Premises without prior written consent of Landlord.  Landlord shall
not be responsible to Tenant for any loss of property from the Premises  however
occurring, or for any damage to the effects of Tenant by such janitors or any of
its employees, or by any other person or any other cause.

9. PROHIBITED ON PREMISES:  Tenant shall not conduct, or permit any other person
   ----------------------
to conduct, any auction upon the Premises,  manufacture or store goods, wares or
merchandise  upon the Premises  without the prior written  approval of Landlord,
except the storage of usual  supplies and  inventory to be used by Tenant in the
conduct of his business,  permit the Premises to be used for gambling,  make any
unusual noises in the Building,  permit to be played  musical  instrument on the
Premises, permit any radio to be played, or television,  recorded or wired music
in such loud manner as to disturb or annoy other tenants,  or permit any unusual
odors to be produced on the Premises. Tenant shall not permit any portion of the
Premises to be occupied as an office for a public stenographer or typewriter, or
for the storage,  manufacture,  or sale of  intoxicating  beverages,  narcotics,
tobacco in any form or as a barber or manicure shop. Canvassing,  soliciting and
peddling in the Building and the Office  Building Area are prohibited and Tenant
shall  cooperate to prevent the same.  No  bicycles,  vehicles or animals of any
kind shall be brought into or kept in or about the Premises.

10. PLUMBING, ELECTRIC AND TELEPHONE WORK: Plumbing facilities shall not be used
    -------------------------------------
for any  purpose  other  than  those for which  they  were  constructed;  and no
sweepings,  rubbish,  ashes,  newspaper or other substances of any kind shall be
thrown into them. Waste and excessive or unusual amounts of electricity or water
is  prohibited.  When  electric  wiring  of any kind is  introduced,  it must be
connected as directed by Landlord,  and no stringing or cutting of wires will be
allowed,  except by prior  written  consent  of  Landlord,  and shall be done by
contractors  approved  by  Landlord.  The number and  locations  of  telephones,
telegraph instruments,  electrical appliances, call boxes, etc. shall be subject
to Landlord's approval.

11.  MOVEMENT OF FURNITURE,  FREIGHT OR BULKY MATTER:  The
     -----------------------------------------------

                                       2
<PAGE>

carrying in or out of freight, furniture or bulky matter of any description must
take  place  during  such  hours as  Landlord  may from time to time  reasonably
determine and only after advance notice to the  superintendent  of the Building.
The persons  employed by Tenant for such work must be  reasonably  acceptable to
the Landlord. Tenant may, subject to these provisions,  move freight, furniture,
bulky  matter,  and other  material  into or out of the  Premises  on  Saturdays
between the hours of 9:00 a.m. and 1:00 p.m.,  provided  Tenant pays  additional
costs, if any,  incurred by Landlord for elevator  operators or security guards,
and for any other expenses  occasioned by such activity of Tenant.  If, at least
three (3) days prior to such  activity,  Landlord  requests that Tenant  deposit
with Landlord, as security of Tenant's obligations to pay such additional costs,
a sum of which Landlord reasonably estimates to be the amount of such additional
cost,  the Tenant shall deposit such sum with Landlord as security of such cost.
There  shall not be used in the  Building  or  Premises,  either by Tenant or by
others in the delivery or receipt of  merchandise,  any hand trucks except those
equipped  with rubber tires and side guards,  and no hand trucks will be allowed
in the elevators without the consent of the superintendent of the Building.

12. SAFES AND OTHER HEAVY  EQUIPMENT:  Landlord  reserves the right to prescribe
    --------------------------------
the  weight  and  position  of all  safes  and other  heavy  equipment  so as to
distribute  properly the weight thereof and to prevent any unsafe condition from
arising.

13.  ADVERTISING:  Landlord shall have the right to prohibit any  advertising by
     -----------
Tenant which in Landlord's  reasonable opinion tends to impair the reputation of
the Building or its  desirability  as a building  for offices,  and upon written
notice from Landlord, Tenant shall refrain from or discontinue such advertising.

14. NON-OBSERVANCE OR VIOLATION OF RULES BY OTHER TENANTS: Landlord shall not be
    -----------------------------------------------------
responsible to Tenant for  non-observance or violation of any of these rules and
regulations by any other tenant.

15.  AFTER HOURS USE:  Landlord  reserves the right to exclude from the Building
     ---------------
between  the hours of 6:00 p.m.  and 8:00  a.m.  and at all hours on  Saturdays,
Sundays  and  Building  Holidays,  all  persons who do not present a pass to the
Building signed by the Tenant.  Each Tenant shall be responsible for all persons
for whom such a pass is issued and shall be liable to the  Landlord for the acts
of such persons.

16.  PARKING:  Tenant  and its  employees  shall  park  their cars only in those
     -------
portions of the parking area designated by Landlord.

17. RESERVATION OF RIGHTS: Landlord hereby reserves to itself any and all rights
    ---------------------
not granted to Tenant  hereunder,  including,  but not limited to, the following
rights  which are  reserved  to  Landlord  for its  purposes  in  operating  the
Building:

     a.  the  exclusive  right to the use of the  name of the  Building  for all
purposes, except that Tenant may use the name as its business address and for no
other purposes; and

     b. the  right  to  change  the name or  address  of the  Building,  without
incurring any

                                       3
<PAGE>

liability to Tenant for doing so; and

     c.  the  right  to  install  and  maintain  a sign on the  exterior  of the
Building; and

     d.  the  exclusive  right to use or  dispose  of the use of the roof of the
Building; and

     e. the right to limit  the space on the  directory  of the  Building  to be
allotted to Tenant; and

     f. the  right to  grant to  anyone  the  right to  conduct  any  particular
business or undertaking in the Building.

18.  HEALTH  AND  SAFETY:  The  Tenant  shall  be  responsible  for  initiating,
     -------------------
maintaining and supervising  all health and safety  precautions  and/or programs
required  by Law in  connection  with  the  Tenant's  use and  occupancy  of the
Premises.

19.  HAZARDOUS  MATERIALS:  The Tenant  shall not store,  introduce or otherwise
     --------------------
permit any material  known to be  hazardous  within the  Premises.  Any material
within the Premises  which is  determined  to be hazardous  shall be removed and
properly disposed of by the Tenant at the Tenant's sole expense.

                                    -- END --


                                       4
<PAGE>




                                    EXHIBIT C
                                    ---------


                                 LANDLORD'S WORK

<PAGE>


                                    EXHIBIT D
                                    ---------


                                BUILDING HOLIDAYS


BUILDING CLOSED ON:


* NEW YEAR'S DAY *


* MEMORIAL DAY *


* INDEPENDENCE DAY *


* LABOR DAY *


* THANKSGIVING DAY *


* CHRISTMAS DAY *


<PAGE>

                                    EXHIBIT E
                                    ---------

                           TENANT ESTOPPEL CERTIFICATE

TO:                          ("       ")  pursuant  to  that  certain
     ----------------------    -------                                 ---------
Agreement (the "Agreement") dated          ,  199 , by and between           and
                                  ---------      -                 ---------
                                             ("Lessor").
- --------------------------------------------

         1. The  undersigned  ("Lessee")  is the lessee under that certain Lease
dated           , 19  , by and between                                        as
      ----------    --                 -------------------------------------
lessor,  and                                      ,  as  lessee  (the  "Lease"),
              ------------------------------------
covering a portion of those certain  premises  commonly  known and designated as
                                             ,   Pennsylvania,   consisting   of
- ---------------------------------------------
approximately            square  feet (the  "Premises").  A true,  complete  and
               --------
correct copy of the Lease is attached hereto as Exhibit "A".

          2. The Lease has not been modified, changed, altered or amended in any
respect  (except as indicated  following this sentence) and is the only lease or
agreement  between the  undersigned  and the Lessor  affecting the Premises.  If
none, state "none".

- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------

          3. The undersigned has made no agreements with Lessor or its agents or
employees,  which are not described in the Lease  concerning free rent,  partial
rent,  rebate of rental  payments  or any other type of rental  concession  with
respect to the Lease (except as indicated  following  this  sentence).  If none,
state "none".

- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------

          4. The undersigned  accepted  possession of the Premises on          ,
                                                                      ---------
19  ,  currently  occupies the  Premises  and has been open for  business  since
  --
          ,  19  . The current term of the Lease began on           ,  19  . The
- ----------     --                                         ----------     --
current  term of the Lease will expire on            ,  19  ,  and Lessee has no
                                           ----------     --
present  right to cancel or  terminate  the Lease  under the terms  thereof,  or
otherwise.  No rent payable pursuant to the Lease has been prepaid for more than
two (2) months,  and no monies otherwise  payable to Lessor under the Lease have
been paid in advance  of the due date  therefor  as set forth in the Lease.  The
fixed  minimum  rent  currently  being paid under the Lease is  $            per
                                                                 ----------
month. Future changes to the fixed minimum rental are as set forth in the Lease.
The undersigned  also pays amounts for percentage  rent,  insurance and property
tax  escalations  based upon the square  footage of the Premises  subject to the
Lease, as set forth in the Lease,  which amounts have been paid to and including
         , 199 .
- ---------     -

          5. The Lease is fully valid and  enforceable  and is currently in full
force and effect.  Neither  Lessor or Lessee is in default  thereunder,  and all
conditions and obligations on the part of Lessor to be fulfilled under the terms
of  the  Lease  have  been


<PAGE>

satisfied or fully performed including,  without limitation, all required tenant
improvements,  allowances,  alterations,  installations  and  construction,  and
payment therefor has been made in full. Lessee has no offset,  claim, defense or
counterclaim  against any rent or other sum payable by Lessee under the Lease or
against any other  obligation  of Lessee under the Lease.  No  condition  exists
which  with  the  giving  of  notice  or the  passage  of time,  or both,  would
constitute a default under the Lease.

          6. Lessee has not suffered any  assignment  of the Lease or sublet the
Premises or any portion thereof, and no person or entity, other than Lessee, has
any  possessory  interest in the Premises or right to occupy the Premises or any
portion thereof, except as permitted under the Lease.

          7. Lessee claims no right,  title or interest in or to the Premises or
right to  possession  of the  Premises,  except as lessee under the terms of the
Lease.  The  Lease  does  not  contain  and the  undersigned  does  not have any
outstanding  options or rights of first  refusal to purchase the Premises or any
portion thereof or the real property of which the Premises are a part, except as
otherwise set forth below. If none, state "none".

- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------

          8. No actions, whether voluntary or otherwise, are pending against the
undersigned under the bankruptcy laws of the United States or any state thereof,
and Lessee knows of no fact or pending or threatened  claim or  litigation  that
might result in the insolvency or bankruptcy of Lessee.

         9. Lessee is a [corporation][limited  partnership][general partnership]
duly  organized and validly  existing and in good standing under the laws of the
State of           [and qualified to do business in the State where the Premises
         ---------
is located].  [          ,  a            ,  owns and holds all of the issued and
               ----------      ----------
outstanding  stock in and of Lessee,  and is a separate and distinct entity from
Lessee].

          10. Lessee's  occupancy of the Premises complies fully with all local,
state and  federal  laws,  ordinances,  codes,  rules,  regulations  and  orders
including,  without  limitation,  those concerning  hazardous wastes,  hazardous
materials,  asbestos,  oil and underground  storage tanks. In addition,  no such
hazardous wastes,  hazardous  materials,  asbestos,  oil or underground  storage
tanks  have been or are  incorporated  in,  stored on or under,  released  from,
treated on,  transported  to or from or disposed  of, on or from the Premises or
any portion thereof.

          11.  All  inspections,   licenses,  permits,  consents,   permissions,
approvals and  certificates  required,  whether by law,  regulation or insurance
standards,  to be made  or  issued  with  respect  to the  conduct  of  Lessee's
business,  the Premises and the use and occupancy of the Premises by Lessee have
been  made by or  issued  by all  necessary  private  parties,  the  appropriate
governmental  or  quasi-governmental  authorities  or other  authorities  having
jurisdiction over the Premises and/or Lessee's  business,  are in full force and
effect,  and Lessee has not received  notification  from any such authority that


                                       2
<PAGE>

Lessee or the Premises is in material  noncompliance with such laws, regulations
or standards,  that the Premises is being used,  operated or occupied unlawfully
or that  Lessee  has  failed  to obtain  such  inspections,  permits,  consents,
permissions, approvals, licenses or certificates, as the case may be. Lessee has
not  received  notice of any  violation or failure to conform with any such law,
ordinance,  regulation, standard, license, permit, consent, permission, approval
or certificate.

          12. All insurance  policies  required to be maintained by Lessee under
the Lease have been  maintained,  are in full force and effect and all  premiums
with respect thereto have been paid in full.

          13. Upon  receipt of notice of the closing of the purchase and sale of
the  Premises as set forth in the  Agreement,  Lessee shall  recognize        as
                                                                        -----
lessor  under the Lease,  and all  payments of rent and other sums due to Lessor
under the Lease and all  communications  permitted  or required  under the Lease
shall be  directed  to            c/o                                 ,  and all
                        ----------       -----------------------------
communications permitted or required under the Lease shall be directed to Lessee
at the address for Lessee set forth in the Lease (except as otherwise  indicated
following this sentence), unless and until otherwise specified in written notice
by the  party to whom  notice  is to be given at such  address.  If none,  state
"none".

- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------

          14.  This  certification  is made to induce                       [to
                                                       --------------------
enter  into the  Agreement]  [to  provide  financing  to  Lessor]  knowing  that
                        is  relying  upon  the  truth  of this  Tenant  Estoppel
- ----------------------
Certificate in [entering into the  Agreement,]  [providing  such  financing] and
that [the acquisition of the Premises by                             pursuant to
                                         --------------------------
the  Agreement]  [the  financing  provided  to Lessor]  shall be deemed good and
valuable  consideration  to Lessee  for the  foregoing  representations  made by
Lessee.


Dated this       day of         , 199 .
          ------       --------      -

                                        LESSEE:

                                        ------------------------------,
                                        a ----------------------------

                                        BY:---------------------------
                                           Name:----------------------
                                           Title:---------------------

                                       3



                           LOAN AND SECURITY AGREEMENT


                                 by and between


                         BIO-IMAGING TECHNOLOGIES, INC.
                             a Delaware corporation,


                                 as the BORROWER



                                       and



                              SILICON VALLEY BANK,
                          a California chartered bank,

                                  as the LENDER



                                 August 10, 1999

<PAGE>

                           LOAN AND SECURITY AGREEMENT
                           ---------------------------


     This LOAN AND  SECURITY  AGREEMENT  (this  "Agreement")  dated  August  10,
1999,between  SILICON VALLEY BANK, a California chartered bank having an address
at 5 Radnor Corporate Center,  Suite 555, 100 Matsonford,  Radnor,  Pennsylvania
19087 ("Bank") and BIO-IMAGING TECHNOLOGIES, INC., a Delaware corporation having
an address at 830 Bear Tavern Road, West Trenton, New Jersey 08628 ("Borrower"),
provides the terms on which Bank will lend to Borrower  and Borrower  will repay
Bank. The parties agree as follows:

1.   ACCOUNTING AND OTHER TERMS
     --------------------------

     1.1  Accounting  terms not  defined  in this  Agreement  will be  construed
following GAAP. Calculations and determinations must be made following GAAP. The
term "financial statements" includes the notes and schedules,  if any. The terms
"including"  and  "includes"   always  mean  "including  (or  includes)  without
limitation"  in this or any Loan Document.  Capitalized  terms in this Agreement
shall  have the  meanings  set forth in  Section  13.  This  Agreement  shall be
construed to impart upon Bank a duty to act reasonably at all times.

2.   LOAN AND TERMS OF PAYMENT
     -------------------------

     2.1  Advances.  Borrower will pay Bank the unpaid  principal  amount of all
          --------
Advances and interest on the unpaid principal amount of the Advances.

     2.2  Revolving Advances.
          ------------------

          (a) Bank will make Advances not exceeding (i) the Committed  Revolving
Line or (ii) the Borrowing Base,  whichever is less. Amounts borrowed under this
Section 2.2 may be repaid and reborrowed during the term of this Agreement.

          (b) To obtain an Advance,  Borrower  must notify Bank by  facsimile or
telephone  by 3:00 p.m.  Eastern  time on the  Business Day the Advance is to be
made.  Borrower must promptly confirm the notification by delivering to Bank the
Payment/Advance  Form  attached  as  EXHIBIT B.  Bank will  credit  Advances  to
                                     ---------
Borrower's deposit account. Bank may make Advances under this Agreement based on
instructions  from a  Responsible  Officer  or his or her  designee  or  without
instructions if the Advances are necessary to meet Obligations which have become
due. Bank may rely on any telephone  notice given by a person whom Bank believes
is a Responsible Officer or designee.  Borrower will indemnify Bank for any loss
Bank suffers due to that reliance.

          (c) The Committed  Revolving Line terminates on the Revolving Maturity
Date, when all Advances are immediately payable.

     2.3  Overadvances.  If Borrower's  Obligations under Section 2.1 exceed the
          ------------
lesser of either (i) the Committed  Revolving  Line or (ii) the Borrowing  Base,
Borrower must immediately pay in cash to Bank the excess.


                                       1
<PAGE>

     2.4  Interest Rate; Payments.
          -----------------------

          (a) Interest  Rate.   Advances  accrue  interest  on  the  outstanding
              --------------
principal  balance at a per annum rate one and one half (1.5%) percentage points
above the Prime Rate. After an Event of Default,  Obligations accrue interest at
five  percent  (5%)  above the rate  effective  immediately  before the Event of
Default.  The interest rate  increases or decreases when the Prime Rate changes.
Interest is computed on a 360-day year for the actual number of days elapsed.

          (b) Payments. Interest is payable on the fifth day of each month. Bank
              --------
may debit any of Borrower's deposit accounts including Account Number
                                                                     -----------
for principal and interest payments or any amounts Borrower owes Bank. Bank will
notify  Borrower  when it debits  Borrower's  accounts.  These  debits are not a
set-off.  Payments received after 3:00 p.m. Eastern time are considered received
at the opening of business on the next  Business Day. When a payment is due on a
day that is not a Business  Day,  the payment is due the next  Business  Day and
additional fees or interest accrue.

     2.5  Fees.  Borrower will pay to Bank:
          ----

          (a) Facility  Fee.  A fully earned,  non-refundable  facility  fee  of
              -------------
ONE THOUSAND and 00/100 DOLLARS ($1,000.00) due on the Closing Date; and

          (b) Bank Expenses.  All Bank Expenses (including reasonable attorneys'
              -------------
fees and expenses for documentation and negotiation of this Agreement)  incurred
through and after the Closing Date when due.

3.   CONDITIONS OF LOANS
     -------------------

     3.1  Conditions Precedent to Initial Advance. Bank's obligation to make the
          ---------------------------------------
initial  Advance is  subject  to the  condition  precedent  that it receive  the
agreements,  documents  and fees it requires and the receipt of the results of a
satisfactory audit of the Borrower's Books and Records and the Collateral.

     3.2  Conditions Precedent to all Advances.  Bank's obligations to make each
          ------------------------------------
Advance, including the initial Advance, is subject to the following:

          (a) timely receipt of any Payment/Advance Form; and

          (b) the representations and warranties in Section 5 must be materially
     true on the date of the  Payment/Advance  Form and on the effective date of
     each Advance and no Event of Default may have  occurred and be  continuing,
     or result from the Advance.  Each Advance is Borrower's  representation and
     warranty on that date that the  representations and warranties in Section 5
     remain true.

4.   CREATION OF SECURITY INTEREST
     -----------------------------

     4.1  Grant of Security Interest. Borrower grants Bank a continuing security
          --------------------------
interest in all presently  existing and later acquired  Collateral to secure all
Obligations  and  performance  of each  of  Borrower's  duties  under  the  Loan
Documents.  Except for Permitted  Liens,  any security  interest will be a first
priority security interest in the Collateral. Bank may place a "hold"



                                       2
<PAGE>

on any deposit  account  pledged as Collateral.  If the Agreement is terminated,
Bank's lien and security interest in the Collateral will continue until Borrower
fully satisfies its Obligations.

5.   REPRESENTATIONS AND WARRANTIES
     ------------------------------

     Borrower represents and warrants as follows:

     5.1  Due  Organization and  Authorization.  Borrower and each Subsidiary is
          ------------------------------------
duly  existing and in good  standing in its state of formation and qualified and
licensed  to do  business  in, and in good  standing  in, any state in which the
conduct  of its  business  or its  ownership  of  property  requires  that it be
qualified.

     The  execution,  delivery and  performance  of the Loan Documents have been
duly authorized,  and do not conflict with Borrower's formation  documents,  nor
constitute an event of default under any material agreement by which Borrower is
bound. Borrower is not in default under any agreement to which or by which it is
bound in which the default could cause a Material Adverse Change.

     5.2  Collateral.  Borrower has good title to the  Collateral, free of Liens
          ----------
except  Permitted  Liens.  The  Eligible   Accounts  are  bona  fide,   existing
obligations,  and the service or property has been performed or delivered to the
account  debtor  or its  agent  for  immediate  shipment  to  and  unconditional
acceptance  by the  account  debtor.  Borrower  has no notice  of any  actual or
imminent  Insolvency  Proceeding  of any account  debtor  whose  accounts are an
Eligible  Account in any  Borrowing  Base  Certificate.  All Inventory is in all
material  respects of good and marketable  quality,  free from material defects.
Borrower  is  the  sole  owner  of  the   Intellectual   Property,   except  for
non-exclusive  licenses  granted  to its  customers  in the  ordinary  course of
business.  Each Patent is valid and enforceable and no part of the  Intellectual
Property has been judged invalid or  unenforceable,  in whole or in part, and no
claim has been  made that any part of the  Intellectual  Property  violates  the
rights of any third party.

     5.3  Litigation.  There  are no  actions  or  proceedings  pending  or,  to
          ----------
Borrower's  knowledge,  threatened by or against  Borrower or any  Subsidiary in
which an adverse decision could cause a Material Adverse Change.

     5.4  No Material Adverse Change in Financial  Statements.  All consolidated
          ---------------------------------------------------
financial  statements for Borrower and any  Subsidiary  delivered to Bank fairly
present in all material respects Borrower's consolidated financial condition and
Borrower's  consolidated results of operations.  There has not been any material
deterioration in Borrower's  consolidated  financial condition since the date of
the most recent financial statements submitted to Bank.

     5.5  Solvency.  The fair  salable  value of  Borrower's  assets  (including
          --------
goodwill minus disposition costs) exceeds the fair value of its liabilities; the
Borrower is not left with  unreasonably  small capital after the transactions in
this Agreement; and Borrower is able to pay its debts (including trade debts) as
they mature.

     5.6  Regulatory  Compliance.  Borrower is not an "investment  company" or a
          ----------------------
company  "controlled"  by an "investment  company" under the Investment  Company
Act.  Borrower is not engaged as one of its  important  activities  in extending
credit for margin stock (under  Regulations T and U of the Federal Reserve Board
of Governors).  Borrower has complied with the Federal Fair Labor Standards Act.
Borrower has not violated any laws,




                                       3
<PAGE>

ordinances  or rules,  the  violation  of which could  cause a Material  Adverse
Change.  None of  Borrower's or any  Subsidiary's  properties or assets has been
used by Borrower or any Subsidiary or, to the best of Borrower's  knowledge,  by
previous Persons, in disposing,  producing,  storing,  treating, or transporting
any hazardous  substance  other than legally.  Borrower and each  Subsidiary has
timely filed all required tax returns and paid,  or made  adequate  provision to
pay, all material taxes. Borrower and each Subsidiary has obtained all consents,
approvals and  authorizations  of, made all  declarations  or filings with,  and
given all notices to, all government  authorities that are necessary to continue
its business as currently conducted, except where the failure to do so could not
reasonably be expected to cause a Material Adverse Change.

     5.7 Subsidiaries.  Borrower does not own any stock, partnership interest or
         ------------
other equity securities except for Permitted Investments.

     5.8 Full Disclosure.  No  representation,  warranty  or other  statement of
         ---------------
Borrower in any  certificate  or written  statement  given to Bank  contains any
untrue  statement of a material fact or omits to state a material fact necessary
to  make  the  statements  contained  in  the  certificates  or  statements  not
misleading.

6.   AFFIRMATIVE COVENANTS
     ---------------------

     Borrower will do all of the following:

     6.1 Government Compliance. Borrower will maintain its and all Subsidiaries'
         ---------------------
corporate  existence and good standing in its jurisdiction of incorporation  and
maintain  qualification in each  jurisdiction in which the failure to so qualify
could have a material  adverse  effect on  Borrower's  business  or  operations.
Borrower will comply, and have each Subsidiary comply, with all laws, ordinances
and  regulations to which it is subject,  noncompliance  with which could have a
material adverse effect on Borrower's business or operations or cause a Material
Adverse Change.

     6.2 Financial Statements, Reports, Certificates.
         -------------------------------------------

         (a)  Borrower will deliver to Bank:  (i) as soon as  available,  but no
later than thirty (30) days after the last day of each month, a company prepared
consolidated balance sheet and income statement covering Borrower's consolidated
operations  during the period,  in a form  acceptable to Bank and certified by a
Responsible  Officer;  (ii) as soon as available,  but no later than ninety (90)
days after the end of Borrower's fiscal year,  audited,  consolidated  financial
statements  prepared  under  GAAP,   consistently  applied,   together  with  an
unqualified  opinion on the financial  statements from an independent  certified
public accounting firm acceptable to Bank; (iii) within five (5) days of filing,
copies of all  statements,  reports and notices  made  available  to  Borrower's
security holders or to any holders of Subordinated  Debt and all reports on Form
10-K,  10-Q and 8-K filed with the  Securities and Exchange  Commission;  (iv) a
prompt report of any legal actions pending or threatened against Borrower or any
Subsidiary  that could result in damages or costs to Borrower or any  Subsidiary
of ONE  HUNDRED  THOUSAND  and 00/100  DOLLARS  ($100,000.00)  or more;  and (v)
budgets, sales projections,  operating plans or other financial information Bank
reasonably requests.

         (b)  At such times as no Advances are  outstanding,  within twenty (20)
days  after the last day of each month and at all other  times,  within ten (10)
days after the last day of

                                       4
<PAGE>

each month, Borrower will deliver to Bank a Borrowing Base Certificate signed by
a  Responsible  Officer in the form of EXHIBIT C, with aged listings of accounts
                                       ---------
receivable and accounts payable.

          (c) Within thirty (30) days after the last day of each month, Borrower
will  deliver  to Bank with the  monthly  financial  statements  required  under
Section 6.2 (a)(i)  above,  a  Compliance  Certificate  signed by a  Responsible
Officer in the form of EXHIBIT D.
                       ---------

          (d) Bank has the  right to audit  Borrower's  Accounts  at  Borrower's
expense,  but the audits will be  conducted no more often than once every twelve
(12) months if no Advances are outstanding  under the Committed  Revolving Line,
once every six (6)  months at all other  times,  unless an Event of Default  has
occurred and is continuing.

     6.3  Inventory;  Returns.  Borrower  will  keep all  Inventory  in good and
          -------------------
marketable condition, free from material defects. Returns and allowances between
Borrower and its account debtors will follow Borrower's  customary  practices as
they exist at the  Closing  Date.  Borrower  must  promptly  notify  Bank of all
returns,  recoveries,  disputes and claims that involve more than FIFTY THOUSAND
and 00/100 DOLLARS ($50,000.00).

     6.4  Taxes.  Borrower will make, and cause each  Subsidiary to make, timely
          -----
payment of all material federal,  state, and local taxes or assessments and will
deliver to Bank, on demand, appropriate certificates attesting to the payment.

     6.5  Insurance.  Borrower will keep its business and the Collateral insured
          ---------
for risks and in amounts,  as Bank  requests.  Insurance  policies  will be in a
form, with companies, and in amounts that are satisfactory to Bank. All property
policies  will have a lender's loss payable  endorsement  showing Bank as a loss
payee and all liability policies will show the Bank as an additional insured and
provide that the insurer must give Bank at least twenty (20) days notice  before
canceling its policy. At Bank's request,  Borrower will deliver certified copies
of policies and evidence of all premium  payments.  Proceeds  payable  under any
policy will, at Bank's option, be payable to Bank on account of the Obligations.

     6.6  Primary Accounts.  Borrower will maintain its primary  depository  and
          ----------------
operating accounts with Bank.

     6.7  Financial Covenants.
          -------------------

     Borrower will maintain as of the last day of each month,  unless  otherwise
noted:

          (a) Quick Ratio.  A ratio of Quick Assets to Current Liabilities minus
              -----------
deferred revenues of at least 2.0 to 1.0.

          (b) Tangible Net Worth. A Tangible Net Worth plus Subordinated Debt of
              ------------------
at least $1,750,000.

     6.8  Further Assurances.  Borrower will execute any further instruments and
          ------------------
take  further  action as Bank  requests to perfect or continue  Bank's  security
interest in the Collateral or to effect the purposes of this Agreement.



                                       5
<PAGE>

7.   NEGATIVE COVENANTS
     ------------------

     Borrower will not do any of the following without the Bank's written
consent, which will not be unreasonably withheld:

     7.1 Dispositions.  Convey,  sell,  lease,  transfer or otherwise dispose of
         ------------
(collectively a "Transfer"),  or permit any of its Subsidiaries to Transfer, all
or any part of its business or property,  other than a Transfer (i) of Inventory
in the ordinary course of business;  (ii) of non-exclusive  licenses and similar
arrangements  for the use of the property of Borrower or its Subsidiaries in the
ordinary course of business; or (iii) of worn-out or obsolete Equipment.

     7.2 Changes in  Business,  Ownership,  Management  or  Business  Locations.
         ----------------------------------------------------------------------
Engage in or permit any of its Subsidiaries to engage in any business other than
the businesses currently engaged in by Borrower or have a material change in its
ownership (other than the sale of Borrower's  equity  securities in a private or
public  offering  or if there  is a change  in the  Borrower's  chief  financial
officer or chief executive officer and the Borrower fails to replace such person
with an officer  acceptable to Bank in its reasonable  discretion  within ninety
(90) days.  Borrower  will not,  without at least thirty (30) days prior written
notice to Bank,  relocate its principal  executive office or add any new offices
or business locations.

     7.3 Mergers or Acquisitions.  Merge or  consolidate,  or permit  any of its
         -----------------------
Subsidiaries  to merge or  consolidate,  with any other Person,  or acquire,  or
permit any of its  Subsidiaries  to  acquire,  all or  substantially  all of the
capital stock or property of another  Person except where (i) such  transactions
do not in the aggregate exceed One Hundred Thousand Dollars  ($100,000) and (ii)
no Event of Default has occurred and is  continuing  or would exist after giving
effect to the  transactions.  A Subsidiary may merge or consolidate into another
Subsidiary or into Borrower.

     7.4 Indebtedness. Create, incur, assume, or be liable for any Indebtedness,
         ------------
or permit any Subsidiary to do so, other than Permitted Indebtedness.

     7.5 Encumbrance.  Create,  incur, or allow any Lien on any of its property,
         -----------
or assign  or convey  any right to  receive  income,  including  the sale of any
Accounts,  or permit any of its  Subsidiaries  to do so,  except  for  Permitted
Liens,  or permit Bank's first priority  security  interest in the Collateral to
change.

     7.6 Investments;  Distributions.  (i) Directly or indirectly acquire or own
         ---------------------------
any  Person,  or  make  any  Investment  in any  Person,  other  than  Permitted
Investments,  or  permit  any of its  Subsidiaries  to do so;  or  (ii)  pay any
dividends or make any distribution or payment or redeem,  retire or purchase any
capital stock, except to existing holders of preferred stock and for repurchases
of stock from former  employees  or  directors  of  Borrower  under the terms of
applicable  repurchase  agreements  in an  aggregate  amount not to exceed FIFTY
THOUSAND DOLLARS ($50,000) in the aggregate in any fiscal year, provided that no
Event of Default has occurred,  is continuing or would exist after giving effect
to the repurchases.

     7.7 Transactions  with  Affiliates.  Directly or indirectly enter or permit
         ------------------------------
any material transaction with any Affiliate, except transactions that are in the
ordinary course of Borrower's business, on terms less favorable to Borrower than
would be obtained in an arm's length transaction with a non-affiliated Person.



                                       6
<PAGE>

     7.8 Subordinated Debt. Make or permit any payment on any Subordinated Debt,
         -----------------
except under the terms of the  Subordinated  Debt, or amend any provision in any
document  relating  to the  Subordinated  Debt,  without  Bank's  prior  written
consent.

     7.9 Compliance.   Undertake as one of its  important  activities  extending
         ----------
credit to purchase or carry margin stock, or use the proceeds of any Advance for
that purpose;  fail to meet the minimum funding  requirements of ERISA, permit a
Reportable Event or Prohibited Transaction,  as defined in ERISA, to occur; fail
to comply with the Federal Fair Labor  Standards Act or violate any other law or
regulation,  if the violation could have a material adverse effect on Borrower's
business or operations or cause a Material Adverse Change,  or permit any of its
Subsidiaries to do so.

8.   EVENTS OF DEFAULT
     -----------------

     Any one of the following is an Event of Default:

     8.1 Payment  Default.  Borrower fails to pay any of the Obligations  within
         ----------------
three (3) days after their due date. During the additional period the failure to
cure the default is not an Event of Default (but no Advances will be made during
the cure period);

     8.2 Covenant Default. Borrower does not perform any obligation in Section 6
         ----------------
or violates  any  covenant in Article 7 or does not perform or observe any other
material term, condition or covenant in this Agreement,  any Loan Documents,  or
in any agreement  between  Borrower and Bank and as to any default under a term,
condition or covenant  that can be cured,  has not cured the default  within ten
(10) days after it occurs,  or if the  default  cannot be cured  within ten (10)
days or cannot be cured  after  Borrower's  attempts in the ten (10) day period,
and the default may be cured  within a  reasonable  time,  then  Borrower has an
additional  time,  (of not more than  thirty  (30)  days) to attempt to cure the
default.  During the additional period the failure to cure the default is not an
Event of Default (but no Credit Extensions will be made during the cure period);

     8.3 Material  Adverse  Change.  A material  impairment in the perfection or
         -------------------------
priority of Bank's  security  interest in the Collateral or in the value of such
Collateral  which  is  not  covered  by  adequate   insurance  occurs;  or  Bank
determines,  based  upon  information  available  to it and  in  its  reasonable
judgment,  that there is a  reasonable  likelihood  that  Borrower  will fail to
comply with one or more of the financial  covenants in Section 6 during the next
succeeding financial reporting period;

     8.4 Attachment.  (i) Any material portion of Borrower's assets is attached,
         ----------
seized,  levied on, or comes into  possession  of a trustee or receiver  and the
attachment,  seizure or levy is not removed in ten (10) days;  (ii)  Borrower is
enjoined,  restrained,  or prevented  by court order from  conducting a material
part of its  business;  (iii) a  judgment  or other  claim  becomes  a Lien on a
material  portion  of  Borrower's  assets;  or (iv) a notice of lien,  levy,  or
assessment is filed against any of Borrower's  assets by any  government  agency
and not paid within ten (10) days after Borrower receives notice.  These are not
Events of Default if stayed or if a bond is posted  pending  contest by Borrower
(but no Advances will be made during the cure period);



                                       7
<PAGE>

     8.5 Insolvency.  (i) Borrower  becomes  insolvent;  (ii) Borrower begins an
         ----------
Insolvency  Proceeding;  or  (iii) an  Insolvency  Proceeding  is begun  against
Borrower  and not  dismissed  or stayed  within  sixty  (60) days (but no Credit
Extensions will be made before any Insolvency Proceeding is dismissed);

     8.6 Misrepresentations. If Borrower or any Person acting for Borrower makes
         ------------------
any  material  misrepresentation  or material  misstatement  now or later in any
warranty or representation  in this Agreement or in any communication  delivered
to Bank or to induce Bank to enter this Agreement or any Loan Document.

9.   BANK'S RIGHTS AND REMEDIES
     --------------------------

     9.1 Rights and Remedies. When an Event of Default occurs and continues Bank
         -------------------
may, without notice or demand, do any or all of the following:

         (a)  Declare all  Obligations  immediately  due and payable  (but if an
Event of Default described in Section 8.5 occurs all Obligations are immediately
due and payable without any action by Bank);

         (b)  Stop advancing  money or extending  credit for Borrower's  benefit
under this Agreement or under any other agreement between Borrower and Bank;

         (c)  Settle or adjust disputes and claims directly with account debtors
for amounts, on terms and in any order that Bank considers advisable;

         (d)  Make  any  payments  and  do any acts it  considers  necessary  or
reasonable  to protect its security  interest in the  Collateral.  Borrower will
assemble  the  Collateral  if  Bank  requests  and  make  it  available  as Bank
designates.  Bank may enter premises  where the Collateral is located,  take and
maintain possession of any part of the Collateral,  and pay, purchase,  contest,
or  compromise  any Lien which  appears to be prior or superior to its  security
interest and pay all expenses incurred.  Borrower grants Bank a license to enter
and occupy any of its premises, without charge, to exercise any of Bank's rights
or remedies;

         (e)  Apply to the Obligations any (i) balances and deposits of Borrower
it holds,  or (ii) any  amount  held by Bank  owing to or for the  credit or the
account of Borrower;

         (f)  Ship, reclaim,  recover, store, finish, maintain,  repair, prepare
for sale, advertise for sale, and sell the Collateral; and

         (g)  Dispose of the Collateral according to the Code.

     9.2 Power of  Attorney.  When an Event of  Default  occurs  and  continues,
         ------------------
Borrower  irrevocably  appoints  Bank as its lawful  attorney  to:  (i)  endorse
Borrower's  name on any checks or other forms of payment or security;  (ii) sign
Borrower's  name on any  invoice  or bill of lading  for any  Account  or drafts
against  account  debtors,  (iii)  make,  settle,  and adjust  all claims  under
Borrower's insurance policies;  (iv) settle and adjust disputes and claims about
the  Accounts  directly  with  account  debtors,  for  amounts and on terms Bank
determines reasonable;  and (v) transfer the Collateral into the name of Bank or
a third party as the Code  permits.  Bank may  exercise the power of attorney to
sign Borrower's name on any documents necessary to perfect



                                       8
<PAGE>

or continue the  perfection  of any security  interest  regardless of whether an
Event of Default has occurred.  Bank's  appointment  as  Borrower's  attorney in
fact,  and all of Bank's  rights  and  powers,  coupled  with an  interest,  are
irrevocable  until all  Obligations  have been fully  repaid and  performed  and
Bank's obligation to provide Credit Extensions terminates.

     9.3 Accounts  Collection.  When an Event of Default  occurs and  continues,
         --------------------
Bank may notify any Person owing Borrower money of Bank's  security  interest in
the funds and  verify the  amount of the  Account.  Borrower  must  collect  all
payments in trust for Bank and, if  requested by Bank,  immediately  deliver the
payments  to Bank in the form  received  from the  account  debtor,  with proper
endorsements for deposit.

     9.4 Bank  Expenses.  If  Borrower  fails to pay any amount or  furnish  any
         --------------
required  proof of  payment  to third  persons  Bank may make all or part of the
payment or obtain  insurance  policies  required  in Section  6.5,  and take any
action under the policies Bank deems prudent.  Any amounts paid by Bank are Bank
Expenses  and  immediately  due  and  payable,  bearing  interest  at  the  then
applicable rate and secured by the Collateral. No payments by Bank are deemed an
agreement to make similar  payments in the future or Bank's  waiver of any Event
of Default.

     9.5 Bank's  Liability for  Collateral.  If Bank  complies  with  reasonable
         ---------------------------------
banking  practices,  it is not liable or responsible for: (a) the safekeeping of
the Collateral;  (b) any loss or damage to the Collateral; (c) any diminution in
the  value  of  the  Collateral;  or (d)  any  act or  default  of any  carrier,
warehouseman,  bailee, or other person.  Borrower bears all risk of loss, damage
or destruction of the Collateral.

     9.6 Remedies  Cumulative.  Bank's rights and remedies under this Agreement,
         --------------------
the Loan Documents, and all other agreements are cumulative. Bank has all rights
and remedies  provided under the Code, by law, or in equity.  Bank's exercise of
one  right or  remedy  is not an  election,  and  Bank's  waiver of any Event of
Default is not a continuing waiver.  Bank's delay is not a waiver,  election, or
acquiescence.  No waiver  is  effective  unless  signed by Bank and then is only
effective for the specific instance and purpose for which it was given.

     9.7 Demand Waiver.  Borrower waives demand,  notice of default or dishonor,
         -------------
notice of payment and nonpayment, notice of any default, nonpayment at maturity,
release, compromise,  settlement,  extension, or renewal of accounts, documents,
instruments,  chattel paper,  and  guaranties  held by Bank on which Borrower is
liable.

10.  NOTICES
     -------

      All notices or demands by any party to this Agreement or any other related
agreement must be in writing and be personally delivered or sent by an overnight
delivery service, by certified mail, postage prepaid,  return receipt requested,
or by  telefacsimile at the addresses listed at the beginning of this Agreement.
A party may change its notice address by giving the other party written notice.



                                       9
<PAGE>

11.  CHOICE OF LAW , VENUE AND JURY TRIAL WAIVER
     -------------------------------------------

     Pennsylvania law governs the Loan Documents without regard to principles of
conflicts of law. Borrower and Bank each submit to the exclusive jurisdiction of
the State and Federal courts in Pennsylvania,  provided, however that if for any
reason Bank cannot avail itself of the courts of Pennsylvania,  Borrower accepts
jurisdiction of the courts and venue in Santa Clara County, California.

     BORROWER  AND BANK EACH WAIVE THEIR RIGHT TO A JURY TRIAL OF ANY CLAIM
     OR CAUSE OF ACTION  ARISING OUT OF OR BASED UPON THIS  AGREEMENT,  THE
     LOAN DOCUMENTS OR ANY CONTEMPLATED  TRANSACTION,  INCLUDING  CONTRACT,
     TORT,  BREACH OF DUTY AND ALL OTHER CLAIMS.  THIS WAIVER IS A MATERIAL
     INDUCEMENT FOR BOTH PARTIES TO ENTER INTO THIS  AGREEMENT.  EACH PARTY
     HAS REVIEWED THIS WAIVER WITH ITS COUNSEL.

12.  GENERAL PROVISIONS
     ------------------

     12.1 Successors and Assigns. This Agreement binds and is for the benefit of
          ----------------------
the successors and permitted assigns of each party. Borrower may not assign this
Agreement or any rights or  Obligations  under it without  Bank's prior  written
consent  which may be granted or  withheld  in Bank's  discretion.  Bank has the
right,  without  the  consent  of or  notice  to  Borrower,  to sell,  transfer,
negotiate,  or grant  participation  in all or any part of, or any  interest in,
Bank's obligations, rights and benefits under this Agreement, the Loan Documents
or any related agreement.

     12.2  Indemnification.  Borrower will  indemnify,  defend and hold harmless
           ---------------
Bank and its  officers,  employees  and  agents  against:  (a) all  obligations,
demands,  claims, and liabilities asserted by any other party in connection with
the transactions  contemplated by the Loan Documents; and (b) all losses or Bank
Expenses  incurred,  or  paid by  Bank  from,  following,  or  consequential  to
transactions between Bank and Borrower (including reasonable attorneys' fees and
expenses),  except  for  losses  caused by Bank's  gross  negligence  or willful
misconduct.

     12.3  Time of Essence.  Time is of the essence for the  performance  of all
           ---------------
Obligations in this Agreement.

     12.4  Severability  of  Provision.  Each  provision  of this  Agreement  is
           ---------------------------
severable from every other  provision in determining the  enforceability  of any
provision.

     12.5  Amendments in Writing, Integration.  All amendments to this Agreement
           ----------------------------------
must be in writing signed by both Bank and Borrower. This Agreement and the Loan
Documents  represent  the  entire  agreement  about  this  subject  matter,  and
supersedes  prior or  contemporaneous  negotiations or agreements.  All prior or
contemporaneous  agreements,  understandings,  representations,  warranties, and
negotiations  between the parties about the subject matter of this Agreement and
the Loan Documents merge into this Agreement and the Loan Documents.

     12.6  Counterparts.  This  Agreement  may  be  executed  in any  number  of
           ------------
counterparts and by different parties on separate  counterparts,  each of which,
when executed and delivered,  are an original,  and all taken together,  are one
Agreement.


                                       10
<PAGE>

     12.7  Survival.  All covenants, representations and warranties made in this
           --------
Agreement continue in full force while any Obligations remain  outstanding.  The
obligations of Borrower in Section 12.2 to indemnify Bank will survive until all
statutes of limitations for actions that may be brought against Bank have run.

     12.8  Confidentiality. In handling any confidential information,  Bank will
           ---------------
exercise  the same  degree of care  that it  exercises  for its own  proprietary
information,   but  disclosure  of  information  may  be  made:  (i)  to  Bank's
subsidiaries  or  affiliates in  connection  with their  present or  prospective
business relations with Borrower;  (ii) to prospective transferees or purchasers
of any interest in the Loans; (iii) as required by law, regulation, subpoena, or
other order,  (iv) as required in connection  with Bank's  examination or audit;
and  (v) as  Bank  considers  appropriate  in  exercising  remedies  under  this
Agreement.  Confidential  information does not include  information that either:
(a) is in the public domain or in Bank's  possession  when disclosed to Bank, or
becomes part of the public domain after  disclosure to Bank; or (b) is disclosed
to Bank by a third  party,  if Bank  does  not  know  that  the  third  party is
prohibited from disclosing the information.

     12.9  Attorneys' Fees,  Costs and  Expenses.   In any action or  proceeding
           -------------------------------------
between  Borrower and Bank  arising out of the Loan  Documents,  the  prevailing
party will be entitled to recover its reasonable attorneys' fees and other costs
and  expenses  incurred,  in  addition  to any  other  relief to which it may be
entitled, whether or not a lawsuit is filed.

13.  DEFINITIONS
     -----------

     13.1  Definitions.
           -----------

     "Accounts" are all existing and later arising  accounts,  contract  rights,
and other  obligations  owed  Borrower in  connection  with its sale or lease of
goods  (including  licensing  software  and other  technology)  or  provision of
services, all credit insurance,  guaranties,  other security and all merchandise
returned or reclaimed by Borrower and  Borrower's  Books  relating to any of the
foregoing.

     "Advance" or "Advances" is a loan advance (or advances) under the Committed
Revolving Line.

     "Affiliate"  of a Person is a Person  that  owns or  controls  directly  or
indirectly the Person,  any Person that controls or is controlled by or is under
common  control  with the Person,  and each of that  Person's  senior  executive
officers,  directors,  partners and, for any Person that is a limited  liability
company, that Person's managers and members.

     "Bank  Expenses"  are all audit fees and expenses and  reasonable  costs or
expenses  (including  reasonable  attorneys'  fees and expenses) for  preparing,
negotiating,   administering,   defending  and  enforcing  the  Loan   Documents
(including appeals or Insolvency Proceedings).

     "Borrower's  Books" are all Borrower's books and records including ledgers,
records  regarding  Borrower's assets or liabilities,  the Collateral,  business
operations  or financial  condition  and all  computer  programs or discs or any
equipment containing the information.



                                       11
<PAGE>

     "Borrowing  Base" is seventy five percent  (75%) of Eligible  Accounts,  as
determined by Bank from Borrower's most recent Borrowing Base Certificate.

     "Business Day" is any day that is not a Saturday,  Sunday or a day on which
the Bank is closed.

     "Closing Date" is the date of this Agreement.

     "Code" is the Pennsylvania Uniform Commercial Code.

     "Collateral" is the property described on Exhibit A.
                                               ---------

     "Committed  Revolving  Line" is a Credit  Extension of $250,000,  provided,
however, from and after such times as Borrower achieves EBITDA exceeding $75,000
for two  (2)  consecutive  fiscal  quarters  and at all  times  thereafter,  the
Committed Revolving Line shall mean a Credit Extension of up to $500,000.

     "Contingent  Obligation"  is,  for  any  Person,  any  direct  or  indirect
liability,  contingent or not, of that Person for (i) any  indebtedness,  lease,
dividend,  letter of credit or other obligation of another such as an obligation
directly or indirectly guaranteed,  endorsed,  co-made,  discounted or sold with
recourse by that  Person,  or for which that  Person is  directly or  indirectly
liable;  (ii) any  obligations  for undrawn letters of credit for the account of
that  Person;  and (iii) all  obligations  from any interest  rate,  currency or
commodity  swap  agreement,  interest  rate cap or  collar  agreement,  or other
agreement or arrangement  designated to protect a Person against  fluctuation in
interest rates,  currency  exchange rates or commodity  prices;  but "Contingent
Obligation"  does not include  endorsements  in the ordinary course of business.
The amount of a Contingent  Obligation is the stated or determined amount of the
primary  obligation  for  which  the  Contingent  Obligation  is made or, if not
determinable,  the maximum reasonably anticipated liability for it determined by
the Person in good  faith;  but the  amount  may not  exceed the  maximum of the
obligations under the guarantee or other support arrangement.

     "Copyrights" are all copyright  rights,  applications or registrations  and
like  protections  in each  work  or  authorship  or  derivative  work,  whether
published  or not (whether or not it is a trade  secret) now or later  existing,
created, acquired or held.

     "Credit Extension" is each Advance or any other extension of credit by Bank
for Borrower's benefit.

     "Current  Assets"  are  amounts  that under GAAP should be included on that
date as current assets on Borrower's consolidated balance sheet.

     "Current   Liabilities"  are  the  aggregate  amount  of  Borrower's  Total
Liabilities which mature within one (1) year.



                                       12
<PAGE>

     "EBITDA" means as to the Borrower for any period of determination  thereof,
the sum of (a) the net  profit  (or loss)  determined  in  accordance  with GAAP
consistently applied, plus (b) interest expense and tax expense for such period,
plus (c)  depreciation  and  amortization of assets for such period,  minus, all
dividends, withdrawals and non cash income.

     "Eligible  Accounts"  are  Accounts in the  ordinary  course of  Borrower's
business that meet all Borrower's representations and warranties in Section 5.2;
but Bank may change  eligibility  standards by giving  Borrower thirty (30) days
prior written notice. Unless Bank agrees otherwise in writing, Eligible Accounts
will not include:

          (a) Accounts  that the account  debtor has not paid within ninety (90)
days of invoice date;

          (b) Accounts for an account  debtor,  fifty  percent  (50%) or more of
whose Accounts have not been paid within ninety (90) days of invoice date;

          (c) Credit balances over ninety (90) days from invoice date;

          (d) Accounts for an account debtor, including Affiliates,  whose total
obligations to Borrower exceed  twenty-five  percent (25%) of all Accounts,  for
the amounts that exceed that percentage, unless Bank approves in writing;

          (e) Accounts for which the account  debtor does not have its principal
place of business in the United States;

          (f) Accounts for which the account debtor is a federal, state or local
government entity or any department, agency, or instrumentality;

          (g) Accounts for which Borrower owes the account  debtor,  but only up
to the amount  owed  (sometimes  called  "contra"  accounts,  accounts  payable,
customer deposits or credit accounts);

          (h) Accounts for demonstration or promotional  equipment,  or in which
goods are consigned,  sales guaranteed,  sale or return, sale on approval,  bill
and hold, or other terms if account debtor's payment may be conditional;

          (i) Accounts  for which the account  debtor is  Borrower's  Affiliate,
officer, employee, or agent;

          (j) Accounts in which the account debtor  disputes  liability or makes
any claim and Bank believes there may be a basis for dispute (but only up to the
disputed  or  claimed  amount),  or if  the  Account  Debtor  is  subject  to an
Insolvency Proceeding, or becomes insolvent, or goes out of business;

          (k) Accounts for which Bank  reasonably  determines  collection  to be
doubtful.

     "Equipment"  is  all  present  and  future  machinery,   equipment,  tenant
improvements,  furniture,  fixtures,  vehicles,  tools, parts and attachments in
which Borrower has any interest.



                                       13
<PAGE>

     "ERISA" is the Employment  Retirement  Income Security Act of 1974, and its
regulations.

     "GAAP" is generally accepted accounting principles.

     "Indebtedness" is (a) indebtedness for borrowed money or the deferred price
of property or services,  such as reimbursement and other obligations for surety
bonds and  letters  of  credit,  (b)  obligations  evidenced  by  notes,  bonds,
debentures  or  similar  instruments,  (c)  capital  lease  obligations  and (d)
Contingent Obligations.

     "Insolvency  Proceeding"  is any  proceeding by or against any Person under
the United States  Bankruptcy  Code, or any other  bankruptcy or insolvency law,
including  assignments  for the benefit of creditors,  compositions,  extensions
generally  with  its   creditors,   or   proceedings   seeking   reorganization,
arrangement, or other relief.

     "Intellectual Property" is:

          (a)  Copyrights,   Trademarks,   Patents,  and  Mask  Works  including
amendments,  renewals,  extensions,  and all licenses or other rights to use and
all license fees and royalties from the use;

          (b) Any trade secrets and any Intellectual Property Rights in computer
software and computer software products now or later existing, created, acquired
or held;

          (c) All design  rights which may be available to Borrower now or later
created, acquired or held;

          (d) Any claims for damages (past,  present or future) for infringement
of any of the rights above,  with the right, but not the obligation,  to sue and
collect  damages for use or  infringement  of the  intellectual  property rights
above;

     All  proceeds  and  products of the  foregoing,  including  all  insurance,
indemnity or warranty payments.

     "Inventory"  is present  and future  inventory  in which  Borrower  has any
interest,  including merchandise,  raw materials,  parts, supplies,  packing and
shipping  materials,  work in process and finished products intended for sale or
lease  or to be  furnished  under a  contract  of  service,  of  every  kind and
description  now or later  owned by or in the custody or  possession,  actual or
constructive, of Borrower, including inventory temporarily out of its custody or
possession or in transit and including returns on any accounts or other proceeds
(including  insurance  proceeds)  from  the  sale or  disposition  of any of the
foregoing and any documents of title.

     "Investment" is any beneficial  ownership of (including stock,  partnership
interest  or other  securities)  any  Person,  or any loan,  advance  or capital
contribution to any Person.

     "Lien"  is a  mortgage,  lien,  deed of  trust,  charge,  pledge,  security
interest or other encumbrance.

     "Loan Documents" are, collectively,  this Agreement, the Note, any note, or
notes or  guaranties  executed  by  Borrower,  and any other  present  or future
agreement between


                                       14
<PAGE>

Borrower and/or for the benefit of Bank in connection  with this Agreement,  all
as amended, extended or restated.

     "Material Adverse Change" has been defined in Section 8.3 hereof.

     "Maturity Date" is the Revolving Maturity Date.

     "Note" means that certain  Revolving  Promissory Note of even date herewith
from the Borrower in favor of the Bank as the same may be amended, supplemented,
restated or modified from time to time.

     "Obligations"  are debts,  principal,  interest,  Bank  Expenses  and other
amounts Borrower owes Bank now or later, including letters of credit and foreign
exchange  contracts,  if any, and including  interest  accruing after Insolvency
Proceedings begin and debts, liabilities, or obligations of Borrower assigned to
Bank.

     "Patents" are patents, patent applications and like protections,  including
improvements,  divisions,  continuations,  renewals,  reissues,  extensions  and
continuations-in-part of the same.

     "Permitted Indebtedness" is:

           (a) Borrower's indebtedness  to Bank under this Agreement or the Loan
Documents;

           (b) Indebtedness existing  on  the  Closing  Date  and  shown  on the
Schedule;

           (c) Subordinated Debt;

           (d) Indebtedness to  trade creditors incurred in the ordinary  course
of business; and

           (e) Indebtedness secured by Permitted Liens;

           (f) Indebtedness  of  Borrower  to  any  Subsidiary  and   Contingent
Obligations of any Subsidiary with respect to obligations of Borrower  (provided
that the primary obligations are not prohibited hereby), and Indebtedness of any
Subsidiary to any other Subsidiary and Contingent  Obligations of any Subsidiary
with respect to obligations of any other  Subsidiary  (provided that the primary
obligations are not prohibited hereby);

           (g) Other  Indebtedness  not otherwise  permitted  by Section 7.4 not
exceeding  FIFTY  THOUSAND  and 00/100  DOLLARS  ($50,000.00)  in the  aggregate
outstanding at any time; and

           (h) Extensions,    refinancings,    modifications,   amendments   and
restatements  of any items of  Permitted  Indebtedness  (a)  through  (f) above,
provided that the principal amount thereof is not increased or the terms thereof
are  not  modified  to  impose  more  burdensome  terms  upon  Borrower  or  its
Subsidiary, as the case may be.

                                       15
<PAGE>

     "Permitted Investments" are:

          (a) Investments  shown on  the  Schedule  and  existing on the Closing
Date; and

          (b) marketable direct obligations issued or unconditionally guaranteed
by the  United  States or its agency or any State  maturing  within one (1) year
from its  acquisition,  (ii) commercial paper maturing no more than one (1) year
after its creation and having the highest  rating from either  Standard & Poor's
Corporation or Moody's Investors Service, Inc., and (iii) Bank's certificates of
deposit  issued  maturing  no more than one (1) year after  issue,  and (iv) any
Investments  permitted by Borrower's  investment policy, as amended from time to
time,  provided that such investment policy (and any such amendment thereto) has
been approved by Bank;

          (c) Investments   consisting  of   the   endorsement   of   negotiable
instruments  for deposit or collection or similar  transactions  in the ordinary
course of Borrower;

          (d) Investments  accepted in connection  with Transfers  permitted  by
Section 7.1;

          (e) Investments  of  Subsidiaries  in  or  to  other  Subsidiaries  or
Borrower  and  Investments  by  Borrower  in  Subsidiaries  not to exceed  FIFTY
THOUSAND and 00/100 DOLLARS ($50,000.00) in the aggregate in any fiscal year

          (f) Investments  consisting  of  (i)  travel  advances  and   employee
relocation loans and other employee loans and advances in the ordinary course of
business,  and (ii) loans to  employees,  officers or directors  relating to the
purchase  of equity  securities  of  Borrower  or its  Subsidiaries  pursuant to
employee  stock  purchase  plans or agreements  approved by Borrower's  Board of
Directors

          (g) Investments  (including debt  obligations)  received in connection
with  the  bankruptcy  or  reorganization  of  customers  or  suppliers  and  in
settlement of delinquent  obligations of, and other disputes with,  customers or
suppliers arising in the ordinary course of business;

          (h) Investments   consisting  of  notes   receivable  of,  or  prepaid
royalties  and other credit  extensions,  to customers and suppliers who are not
Affiliates, in the ordinary course of business; provided that this paragraph (h)
shall not apply to Investments of Borrower in any Subsidiary;

          (i) Joint ventures or strategic alliances  consisting of the licensing
of  technology,  the  development  of  technology  or the providing of technical
support,  provided  that any cash  investments  by Borrower do not exceed  FIFTY
THOUSAND and 00/100  DOLLARS  ($50,000.00)  in the aggregate in any fiscal year;
and

          (j) Other  Investments  not  otherwise  permitted  by Section  7.7 not
exceeding  FIFTY  THOUSAND  and 00/100  DOLLARS  ($50,000.00)  in the  aggregate
outstanding at any time.

                                       16
<PAGE>

     "Permitted Liens" are:

          (a) Liens  existing on the Closing  Date and shown on the  Schedule or
arising under this Agreement or other Loan Documents;

          (b) Liens for taxes, fees,  assessments or other government charges or
levies,  either not  delinquent  or being  contested in good faith and for which
Borrower maintains adequate reserves on its Books, if they have no priority over
any of Bank's security interests;

          (c) Purchase money Liens (i) on Equipment acquired or held by Borrower
or its Subsidiaries incurred for financing the acquisition of the Equipment,  or
(ii)  existing  on  equipment  when  acquired,  if the Lien is  confined  to the
property and improvements and the proceeds of the equipment;

          (d) Leases or  subleases  and licenses or  sublicenses  granted in the
ordinary course of Borrower's business, if the leases,  subleases,  licenses and
sublicenses permit granting Bank a security interest;

          (e) Liens  incurred in the  extension,  renewal or  refinancing of the
indebtedness  secured by Liens  described in (a) through (c), but any extension,
renewal or  replacement  Lien must be limited to the property  encumbered by the
existing Lien and the principal amount of the indebtedness may not increase;

          (f) Liens  arising  from   judgments,   decrees   or   attachments  in
circumstances not constituting an Event of Default under Section 8.4 or 8.7;

          (g) Liens  in  favor  of  other  financial  institutions  arising   in
connection with Borrower's deposit accounts held at such institutions,  provided
that Bank has a perfected  security interest in the amounts held in such deposit
accounts; and

          (h) Other Liens not described  above arising in the ordinary course of
business  and not having or not  reasonably  likely to have a  material  adverse
effect on Borrower and its Subsidiaries taken as a whole.

     "Person"  is any  individual,  sole  proprietorship,  partnership,  limited
liability company, joint venture, company, trust,  unincorporated  organization,
association,  corporation,  institution, public benefit corporation, firm, joint
stock company, estate, entity or government agency.

     "Prime Rate" is Bank's most recently  announced "prime rate," even if it is
not Bank's lowest rate.

     "Quick Assets" is, on any date, the Borrower's  consolidated,  unrestricted
cash, cash  equivalents,  total trade accounts  receivable and investments  with
maturities of less than twelve (12) months determined according to GAAP.

     "Responsible   Officer"  is  each  of  the  Chief  Executive  Officer,  the
President, the Chief Financial Officer and the Controller of Borrower.

     "Revolving Maturity Date" is August 5, 2000.

                                       17
<PAGE>

     "Schedule" is any attached schedule of exceptions.

     "Subordinated Debt" is debt incurred by Borrower subordinated to Borrower's
debt to Bank (and identified as subordinated by Borrower and Bank).

     "Subsidiary" is for any Person, joint venture, or any other business entity
of which  more than fifty  percent  (50%) of the  voting  stock or other  equity
interests is owned or controlled,  directly or indirectly,  by the Person or one
or more Affiliates of the Person.

     "Tangible  Net Worth" is, on any date,  the  consolidated  total  assets of
Borrower  and its  Subsidiaries  minus,  (i)  any  amounts  attributable  to (a)
                                 -----
goodwill,  (b) intangible  items such as unamortized  debt discount and expense,
Patents,  trade and  service  marks  and  names,  Copyrights  and  research  and
development  expenses  except  prepaid  expenses,  and (c)  reserves not already
deducted from assets, and (ii) Total Liabilities plus Subordinated Debt.
                      ---

     "Total Liabilities" is on any day,  obligations that should, under GAAP, be
classified as liabilities on Borrower's  consolidated  balance sheet,  including
all Indebtedness,  and current portion Subordinated Debt allowed to be paid, but
excluding all other Subordinated Debt.

     "Trademarks"  are  trademark  and service mark rights,  registered  or not,
applications to register and registrations and like protections,  and the entire
goodwill of the business of Borrower connected with the trademarks.

                         [SIGNATURES BEGIN ON NEXT PAGE]




                                       18
<PAGE>

BORROWER:                                  BANK:

BIO-IMAGING TECHNOLOGIES, INC.,            SILICON VALLEY BANK,
 a Delaware corporation                    a California chartered bank
   --------


By: /s/ Robert J. Phillips                 By:  /s/ Ash R. Lilani
   ------------------------------------        -------------------------------
Print Name: Robert J. Phillips                 Ash R. Lilani
Title: Vice President & Chief Financial        Senior Vice President
         Officer


                                           SILICON VALLEY BANK


                                           By:
                                              --------------------------------
                                                Name:
                                                Title:


                                       19
<PAGE>

                                    EXHIBIT A
                                    ---------

                            DESCRIPTION OF COLLATERAL
                            -------------------------


     The Collateral  consists of all of Borrower's right,  title and interest in
and to the following:

     All goods and equipment now owned or hereafter acquired, including, without
limitation,  all machinery,  fixtures,  vehicles  (including  motor vehicles and
trailers),  and any  interest  in any of the  foregoing,  and  all  attachments,
accessories,   accessions,   replacements,    substitutions,    additions,   and
improvements to any of the foregoing, wherever located;

     All  inventory,  now  owned  or  hereafter  acquired,   including,  without
limitation,  all  merchandise,  raw  materials,  parts,  supplies,  packing  and
shipping  materials,  work in  process  and  finished  products  including  such
inventory  as is  temporarily  out of  Borrower's  custody or  possession  or in
transit and including any returns upon any accounts or other proceeds, including
insurance  proceeds,  resulting  from  the  sale  or  disposition  of any of the
foregoing and any documents of title representing any of the above;

     All  contract  rights  and  general  intangibles  now  owned  or  hereafter
acquired,  including, without limitation,  goodwill,  trademarks,  servicemarks,
trade  styles,  trade  names,  patents,  patent  applications,  leases,  license
agreements,   franchise  agreements,   blueprints,  drawings,  purchase  orders,
customer lists, route lists, infringements,  claims, computer programs, computer
discs, computer tapes, literature,  reports, catalogs, design rights, income tax
refunds, payments of insurance and rights to payment of any kind;

     All  now  existing  and  hereafter  arising   accounts,   contract  rights,
royalties,  license rights and all other forms of obligations  owing to Borrower
arising out of the sale or lease of goods,  the  licensing of  technology or the
rendering of services by Borrower, whether or not earned by performance, and any
and all credit insurance,  guaranties,  and other security therefor,  as well as
all merchandise returned to or reclaimed by Borrower;

     All documents, cash, deposit accounts, securities, securities entitlements,
securities accounts,  investment property,  financial assets, letters of credit,
certificates  of deposit,  instruments  and chattel paper now owned or hereafter
acquired and Borrower's Books relating to the foregoing;

     All copyright rights,  copyright applications,  copyright registrations and
like protections in each work of authorship and derivative work thereof, whether
published  or  unpublished,  now owned or hereafter  acquired;  all trade secret
rights,  including  all rights to  unpatented  inventions,  know-how,  operating
manuals, license rights and agreements and confidential  information,  now owned
or  hereafter  acquired;  all mask  work or  similar  rights  available  for the
protection of semiconductor  chips, now owned or hereafter acquired;  all claims
for damages by way of any past,  present and future  infringement  of any of the
foregoing; and



                                       20
<PAGE>

     All  Borrower's  Books  relating to the  foregoing  and any and all claims,
rights and interests in any of the above and all  substitutions  for,  additions
and accessions to and proceeds thereof.




                                       21
<PAGE>

                                    EXHIBIT B
                                    ---------

                   LOAN PAYMENT/ADVANCE TELEPHONE REQUEST FORM
                   -------------------------------------------

              DEADLINE FOR SAME DAY PROCESSING IS 3:00 P.M., E.S.T.


TO:  CENTRAL CLIENT SERVICE DIVISION                  DATE:
                                                           -----------------
FAX#:  (   )    -                                     TIME:
        ---  --- ----                                      -----------------
- --------------------------------------------------------------------------------

FROM:
     ---------------------------------------------------------------------------
                             CLIENT NAME (BORROWER)

REQUESTED BY:
             -------------------------------------------------------------------
                            AUTHORIZED SIGNER'S NAME

AUTHORIZED SIGNATURE:
                     -----------------------------------------------------------

PHONE NUMBER:
             -------------------------------------------------------------------

FROM ACCOUNT #                            TO ACCOUNT #
              -------------------------                -------------------------

REQUESTED TRANSACTION TYPE                REQUEST DOLLAR AMOUNT
- --------------------------                ---------------------

PRINCIPAL INCREASE (ADVANCE)              $
                                           -------------------------------------
PRINCIPAL PAYMENT (ONLY)                  $
                                           -------------------------------------
INTEREST PAYMENT (ONLY)                   $
                                           -------------------------------------
PRINCIPAL AND INTEREST (PAYMENT)          $
                                           -------------------------------------

OTHER INSTRUCTIONS:
                   -------------------------------------------------------------
- --------------------------------------------------------------------------------

All Borrower's representations and warranties in the Loan and Security Agreement
are true,  correct  and  complete  in all  material  respects on the date of the
telephone request for and Advance confirmed by this Borrowing  Certificate;  but
those  representations and warranties  expressly referring to another date shall
be  true,  correct  and  complete  in all  material  respects  as of that  date.



- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------
                                  BANK USE ONLY

TELEPHONE REQUEST:
- ------------------

The following  person is  authorized  to request the loan payment  transfer/loan
advance on the advance designated account and is known to me.

- --------------------------------------            ------------------------------
         Authorized Requester                                Phone #

- --------------------------------------            ------------------------------
           Received By (Bank)                                Phone #


                    ----------------------------------------
                           Authorized Signature (Bank)


- --------------------------------------------------------------------------------
<PAGE>

                                    EXHIBIT C
                                    ---------

                           BORROWING BASE CERTIFICATE
                           --------------------------

================================================================================

Borrower:  BIO-IMAGING TECHNOLOGIES, INC.       Lender:   Silicon Valley Bank


Commitment Amount:  up to $500,000

================================================================================

ACCOUNTS RECEIVABLE

     1.   Accounts Receivable Book Value as of              $
                                              --------       -------------------
     2.   Additions (please explain on reverse)             $
                                                             -------------------
     3.   TOTAL ACCOUNTS RECEIVABLE                         $
                                                             -------------------

ACCOUNTS RECEIVABLE DEDUCTIONS (without duplication)
     4.   Amounts over 90 days due                          $
                                                             -------------------
     5.   Balance of 50% over 90 day accounts               $
                                                             -------------------
     6.   Credit balances over 90 days                      $
                                                             -------------------
     7.   Concentration Limits                              $
                                                             -------------------
     8.   Foreign Accounts                                  $
                                                             -------------------
     9.   Governmental Accounts                             $
                                                             -------------------
     10.  Contra Accounts                                   $
                                                             -------------------
     11.  Promotion or Demo Accounts                        $
                                                             -------------------
     12.  Intercompany/Employee Accounts                    $
                                                             -------------------
     13.  Other (please explain on reverse)                 $
                                                             -------------------
     14.  TOTAL ACCOUNTS RECEIVABLE DEDUCTIONS              $
                                                             -------------------
     15.  Eligible Accounts (#3 minus #14)                  $
                                                             -------------------
     16.  LOAN VALUE OF ACCOUNTS ( 75% of #15)              $
                                                             -------------------

BALANCES
     17.  Maximum Loan Amount ($500,000 or $250,000)        $
                                                             -------------------
     18.  Total Funds Available [Lesser of #17 or #16]      $
                                                             -------------------
     19.  Present balance owing on Line of Credit           $
                                                             -------------------
     20.  Outstanding under Sublimits ( )                   $
                                                             -------------------
     21.  RESERVE POSITION (#17 minus #19 and #20)          $
                                                             -------------------

The undersigned represents and warrants that this is true, complete and correct,
and that the  information in this Borrowing Base  Certificate  complies with the
representations  and warranties in the Loan and Security  Agreement  between the
undersigned and Silicon Valley Bank.

COMMENTS:





By:
   -------------------------------
        Authorized Signer

<PAGE>

                                    EXHIBIT D
                                    ---------

                             COMPLIANCE CERTIFICATE
                             ----------------------


TO:        SILICON VALLEY BANK


FROM:      BIO-IMAGING TECHNOLOGIES, INC.


     The  undersigned  authorized  officer  of  BIO-IMAGING  TECHNOLOGIES,  INC.
certifies that under the terms and conditions of the Loan and Security Agreement
between  Borrower  and Bank  (the  "Agreement"),  (i)  Borrower  is in  complete
compliance  for the period ending                   with all required  covenants
                                  -----------------
except  as noted  below  and  (ii) all  representations  and  warranties  in the
Agreement are true and correct in all material  respects on this date.  Attached
are the required documents  supporting the certification.  The Officer certifies
that  these are  prepared  in  accordance  with  Generally  Accepted  Accounting
Principles  (GAAP)  consistently  applied  from one period to the next except as
explained in an accompanying letter or footnotes.  The Officer acknowledges that
no  borrowings  may be  requested  at any  time or date  of  determination  that
Borrower is not in compliance  with any of the terms of the Agreement,  and that
compliance is determined not just at the date this certificate is delivered.

  Please indicate compliance status by circling Yes/No under "Complies" column.

     Reporting Covenant              Required                     Complies
     ------------------              --------                     --------

     Monthly financial statements    Monthly within 30 days        Yes  No
     Annual (CPA Audited)            FYE within 90 days            Yes  No
     A/R Agings                      Monthly within 30 days        Yes  No
     10k and 10Q                     Within 5 days                 Yes  No

     Financial Covenant              Required         Actual      Complies
     ------------------              --------         ------      --------

     Maintain on a Monthly Basis:
      Minimum Quick Ratio            2.00:1.0              :1.0    Yes   No
                                                      -----
      Minimum Tangible Net Worth     $1,750,000       $            Yes   No
                                                       --------


                                               ---------------------------------
Comments Regarding Exceptions: See Attached.                BANK USE ONLY

                                               Received by:
                                                           ---------------------
Sincerely,                                                   AUTHORIZED SIGNER

                                               Date:
==========================================          ----------------------------
SIGNATURE
                                               Verified:
                                                        ------------------------
==========================================                AUTHORIZED SIGNER
TITLE
                                               Date:
                                                    ----------------------------
==========================================
DATE                                           Compliance Status:     Yes     No

                                               ---------------------------------
<PAGE>
                            REVOLVING PROMISSORY NOTE
                            -------------------------


$500,000                                                  Radnor, Pennsylvania
                                                               August 10, 1999


     FOR VALUE RECEIVED,  the  undersigned,  BIO-IMAGING  TECHNOLOGIES,  INC., a
Delware corporation  ("Borrower") promises to pay to the order of SILICON VALLEY
BANK, a  California-chartered  bank ("Bank"), at such place as the holder hereof
may  designate,  in lawful money of the United States of America,  the aggregate
unpaid principal amount of all advances ("Advances") made by Bank to Borrower in
accordance  with the terms and  conditions  of the Loan and  Security  Agreement
between  Borrower and Bank of even date  herewith,  as amended from time to time
(the  "Loan  Agreement"),  up to a  maximum  principal  amount  of Five  Hundred
Thousand  Dollars  ($500,000)  ("Principal  Sum"),  or so much thereof as may be
advanced or readvanced and remains  unpaid.  Borrower shall also pay interest on
the aggregate unpaid principal amount of such Advances, as follows:

     Commencing as of the date hereof and continuing  until repayment in full of
all sums due  hereunder,  the unpaid  Principal  Sum shall bear  interest at the
variable rate of interest,  per annum,  most  recently  announced by Bank as its
"prime rate,"  whether or not such  announced  rate is the lowest rate available
from Bank (the "Prime Rate"),  plus one and one half percent  (1.50%) per annum.
The rate of  interest  charged  under this Note  shall  change  immediately  and
contemporaneously  with any change in the Prime Rate. All interest payable under
the terms of this Note shall be  calculated  on the basis of a 360-day  year and
the actual number of days elapsed.

     The unpaid  Principal  Sum,  together with interest  thereon at the rate or
rates provided above, shall be payable as follows:

            (a) Interest  only on the unpaid  principal  amount shall be due and
payable monthly in arrears,  commencing September 5, 1999, and continuing on the
same day of each calendar month thereafter to maturity; and

            (b) Unless  sooner paid,  the unpaid  Principal  Sum,  together with
interest accrued and unpaid thereon,  shall be due and payable in full on August
5, 2000.

     The fact that the  balance  hereunder  may be  reduced to zero from time to
time pursuant to the Loan Agreement  will not affect the continuing  validity of
this  Note or the  Loan  Agreement,  and the  balance  may be  increased  to the
Principal Sum after any such reduction to zero.

     This Note is the "Note" described in the Loan Agreement, to which reference
is hereby made for a more complete  statement of the terms and conditions  under
which the loans and advances  evidenced hereby are made. This Note is secured as
provided  in the Loan  Agreement.



<PAGE>

All  capitalized  terms used  herein and not  otherwise  defined  shall have the
meanings given to such terms in the Loan Agreement.

     Borrower  irrevocably waives the right to direct the application of any and
all  payments  at any time  hereafter  received  by Bank  from or on  behalf  of
Borrower and  Borrower  irrevocably  agrees that Bank shall have the  continuing
exclusive  right to apply  any and all such  payments  against  the then due and
owing  obligations of Borrower as Bank may deem  advisable.  In the absence of a
specific  determination  by Bank with respect  thereto,  all  payments  shall be
applied in the following order: (a) then due and payable fees and expenses;  (b)
then due and payable interest payments and mandatory  prepayments;  and (c) then
due and payable principal payments and optional prepayments.

     Bank is hereby  authorized  by  Borrower  to  endorse  on Bank's  books and
records each Advance made by Bank under this Note and the amount of each payment
or  prepayment  of  principal of each such  Advance  received by Bank;  it being
understood,  however, that failure to make any such endorsement (or any error in
notation)  shall not affect the obligations of Borrower with respect to Advances
made  hereunder,  and  payments of  principal  by Borrower  shall be credited to
Borrower  notwithstanding  the  failure  to make a  notation  (or any  errors in
notation) thereof on such books and records.

     The occurrence of any one or more of the following  events shall constitute
an event of default (individually,  an "Event of Default" and collectively,  the
"Events of Default") under the terms of this Note:

            (a) The  failure  of  Borrower  to pay to Bank  when due any and all
amounts payable by Borrower to Bank under the terms of this Note,  which failure
continues for three (3) days; or

            (b) The occurrence of an event of default (as defined therein) under
the terms and conditions of any of the other Loan Documents.

     Upon the  occurrence  of an Event of  Default,  at the option of Bank,  all
amounts  payable  by  Borrower  to Bank  under  the  terms  of this  Note  shall
immediately  become  due and  payable  by  Borrower  to Bank  without  notice to
Borrower or any other person, and Bank shall have all of the rights, powers, and
remedies available under the terms of this Note, any of the other Loan Documents
and all  applicable  laws.  Borrower and all  endorsers,  guarantors,  and other
parties who may now or in the future be primarily or secondarily  liable for the
payment  of the  indebtedness  evidenced  by this Note  hereby  severally  waive
presentment,  protest  and demand,  notice of  protest,  notice of demand and of
dishonor and  non-payment of this Note and expressly agree that this Note or any
payment hereunder may be extended from time to time without in any way affecting
the liability of Borrower, guarantors and endorsers.


                                       2
<PAGE>

     Borrower  promises to pay all costs and expense of  collection of this Note
and to pay all reasonable  attorneys' fees incurred in such collection,  whether
or not there is a suit or action,  or in any suit or action to collect this Note
or in any appeal thereof.  Borrower waives presentment,  demand, protest, notice
of protest,  notice of  dishonor,  notice of  nonpayment,  and any and all other
notices and demands in  connection  with the delivery,  acceptance,  performance
default or  enforcement  of this Note,  as well as any  applicable  statutes  of
limitations.  No delay by Bank in exercising any power or right  hereunder shall
operate  as a waiver  of any power or right.  Time is of the  essence  as to all
obligations hereunder.

     This Note is issued pursuant to the Loan Agreement,  which shall govern the
rights and obligations of Borrower with respect to all obligations hereunder.

     Borrower  acknowledges  and agrees  that this Note shall be governed by the
laws  of  the  Commonwealth  of  Pennsylvania,   excluding   conflicts  of  laws
principles, even though for the convenience and at the request of Borrower, this
Note may be executed elsewhere.

     BORROWER  ACCEPTS  FOR  ITSELF  AND  IN  CONNECTION  WITH  ITS  PROPERTIES,
UNCONDITIONALLY, THE NON-EXCLUSIVE JURISDICTION OF ANY STATE OR FEDERAL COURT OF
COMPETENT  JURISDICTION IN THE COMMONWEALTH OF PENNSYLVANIA IN ANY ACTION, SUIT,
OR PROCEEDING  OF ANY KIND,  AGAINST IT WHICH ARISES OUT OF OR BY REASON OF THIS
AGREEMENT; PROVIDED, HOWEVER, THAT IF FOR ANY REASON BANK CANNOT AVAIL ITSELF OF
THE COURTS OF  PENNSYLVANIA,  BORROWER  ACCEPTS  JURISDICTION  OF THE COURTS AND
VENUE IN SANTA CLARA  COUNTY,  CALIFORNIA.  BORROWER  AND BANK EACH HEREBY WAIVE
THEIR  RESPECTIVE  RIGHTS TO A JURY TRIAL OF ANY CLAIM OR CAUSE OF ACTION  BASED
UPON OR  ARISING  OUT OF ANY OF THE LOAN  DOCUMENTS  OR ANY OF THE  TRANSACTIONS
CONTEMPLATED  THEREIN,  INCLUDING CONTRACT CLAIMS,  TORT CLAIMS,  BREACH OF DUTY
CLAIMS, AND ALL OTHER COMMON LAW OR STATUTORY CLAIMS.  EACH PARTY RECOGNIZES AND
AGREES THAT THE FOREGOING  WAIVER  CONSTITUTES A MATERIAL  INDUCEMENT  FOR IT TO
ENTER  INTO THIS  AGREEMENT.  EACH PARTY  REPRESENTS  AND  WARRANTS  THAT IT HAS
REVIEWED  THIS  WAIVER  WITH  ITS  LEGAL  COUNSEL  AND  THAT  IT  KNOWINGLY  AND
VOLUNTARILY  WAIVES  ITS JURY TRIAL  RIGHTS  FOLLOWING  CONSULTATION  WITH LEGAL
COUNSEL.



                                       3
<PAGE>

     IN WITNESS WHEREOF, Borrower has caused this Note to be executed under seal
by its duly authorized officers as of the date first written above.



WITNESS/ATTEST:                       BIO-IMAGING TECHNOLOGIES, INC.



/s/ William J. Thomas                 By: /s/ Robert J. Phillips      (SEAL)
- ------------------------------           -----------------------------
                                         Name:  Robert J. Phillips
                                         Title: Vice President & Chief Financial
                                                  Officer


                                       4




                               SILICON VALLEY BANK
                                3003 Tasman Drive
                             Santa Clara, Ca. 95054
                       (408) 654-1000 - Fax (408) 980-6410

                     ACCOUNTS RECEIVABLE PURCHASE AGREEMENT

     This Accounts  Receivable  Purchase  Agreement (the "Agreement") is made on
this TWENTY  SECOND day of DECEMBER  1999,  by and between  Silicon  Valley Bank
("Buyer")  having  a place  of  business  at the  address  specified  above  and
BIO-IMAGING  TECHNOLOGIES,  INC., a DELAWARE corporation,  ("Seller") having its
principal place of business and chief executive  office at 830 Bear Tavern Road,
West Trenton, New Jersey 08628.

1.  DEFINITIONS.  When  used  herein,  the  following  terms  shall  have  the
following meanings.
     1.1.  "Account  Balance"  shall mean, on any given day, the gross amount of
all Purchased Receivables unpaid on that day.
     1.2.  "Account  Debtor" shall have the meaning set forth in the  California
Uniform  Commercial  Code and shall  include any person  liable on any Purchased
Receivable,  including  without  limitation,  any  guarantor  of  the  Purchased
Receivable and any issuer of a letter of credit or banker's acceptance.
     1.3. "Adjustments" shall mean all discounts, allowances, returns, disputes,
counterclaims,  offsets,  defenses,  rights of  recoupment,  rights  of  return,
warranty  claims,  or short  payments,  asserted  by or on behalf of any Account
Debtor with respect to any Purchased Receivable.
     1.4.  "Administrative  Fee"  shall  have  the  meaning  as set  forth  in
Section 3.3 hereof.
     1.5.  "Advance" shall have the meaning set forth in Section 2.2 hereof.
     1.6.  "Collateral" shall have the meaning set forth in Section 8 hereof
     1.7.  "Collections"  shall mean all good funds received by Buyer from or on
behalf of an Account Debtor with respect to Purchased Receivables.
     1.8 "Compliance  Certificate" shall mean a certificate,  in a form provided
by Buyer to Seller,  which  contains the  certification  of the chief  financial
officer of Seller that, among other things, the  representations  and warranties
set forth in this Agreement are true and correct as of the date such certificate
is delivered.
     1.9 "Current Assets" are amounts that under GAAP should be included on that
date as current assets on Seller's consolidated balance sheet.
     1.10 "Deferred  Maintenance  Revenue" is all amounts received in advance of
performance under maintenance contracts and not yet recognized as revenue.
     1.11.  "Event of  Default"  shall have the  meaning  set forth in Section 9
hereof.
     1.12.  "Finance  Charges"  shall have the  meaning set forth in Section 3.2
hereof.
     1.13.  "Invoice  Transmittal"  shall mean a writing signed by an authorized
representative  of Seller which  accurately  identifies  the  receivables  which
Buyer, at its election,  may purchase, and includes for each such receivable the
correct amount owed by the Account  Debtor,  the name and address of the Account
Debtor, the invoice number, the invoice date and the account code.
     1.14.  "Obligations"  shall mean all  advances,  financial  accommodations,
liabilities, obligations, covenants and duties owing, arising, due or payable by
Seller to Buyer of any kind or nature,  present or future,  arising  under or in
connection  with  this  Agreement  or under any other  document,  instrument  or
agreement,  whether or not evidenced by any note, guarantee or other instrument,
whether  arising  on  account  or  by  overdraft,  whether  direct  or  indirect
(including  those  acquired by assignment)  absolute or  contingent,  primary or
secondary,  due or to become due,  now owing or hereafter  arising,  and however
acquired;   including,   without  limitation,  all  Advances,  Finance  Charges,
Administrative Fees, interest, Repurchase Amounts, fees, expenses,  professional
fees and attorneys'  fees and any other sums  chargeable to Seller  hereunder or
otherwise.
     1.15. "Purchased  Receivables" shall mean all those accounts,  receivables,
chattel paper,  instruments,  contract rights,  documents,  general intangibles,
letters of credit, drafts,  bankers acceptances,  and rights to payment, and all
proceeds  thereof (all of the  foregoing  being  referred to as  "receivables"),
arising out of the invoices and other agreements identified on or delivered with
any Invoice  Transmittal  delivered  by Seller to Buyer  which  Buyer  elects to
purchase and for which Buyer makes an Advance.
     1.16. "Refund" shall have the meaning set forth in Section 3.5 hereof.
     1.17. "Reserve" shall have the meaning set forth in Section 2.4 hereof.
     1.18.  "Repurchase  Amount" shall have the meaning set forth in Section 4.2
hereof.
     1.19.  "Reconciliation  Date"  shall  mean  the last  calendar  day of each
Reconciliation Period.
     1.20 "Reconciliation Period" shall mean each calendar month of every year.
     1.21  "Subordinated  Debt"  is debt  occurred  by  Seller  subordinated  to
Seller's debt to Buyer (and identified as subordinated by Seller and Buyer .
     1.22 "Total  Liabilities"  is on any day,  obligations  that should,  under
GAAP, be classified  as  liabilities  on Seller's  consolidated  balance  sheet,
including all indebtedness,  and current portion Subordinated Debt allowed to be
paid, but excluding all other Subordinated Debt.







                                        Page 1 of 7
<PAGE>

2. PURCHASE AND SALE OF RECEIVABLES.

     2.1. OFFER TO SELL RECEIVABLES.  During the term hereof,  and provided that
there does not then  exist any Event of  Default or any event that with  notice,
lapse of time or  otherwise  would  constitute  an Event of Default,  Seller may
request that Buyer purchase  receivables and Buyer may, in its sole  discretion,
elect to  purchase  receivables.  Seller  shall  deliver  to  Buyer  an  Invoice
Transmittal  with respect to any  receivable for which a request for purchase is
made. An authorized representative of Seller shall sign each Invoice Transmittal
delivered  to Buyer.  Buyer  shall be  entitled  to rely on all the  information
provided  by Seller to Buyer on or with the Invoice  Transmittal  and to rely on
the signature on any Invoice Transmittal as an authorized signature of Seller.

     2.2. ACCEPTANCE OF RECEIVABLES.  Buyer shall have no obligation to purchase
any  receivable  listed on an Invoice  Transmittal.  Buyer may exercise its sole
discretion  in approving  the credit of each Account  Debtor  before  buying any
receivable.  Upon acceptance by Buyer of all or any of the receivables described
on any Invoice Transmittal, Buyer shall pay to Seller 80 (%) percent of the face
                                                      ------
amount of each  receivable  Buyer  desires to  purchase.  Buyer will not net out
deferred revenue related to each specific Account Debtor, if Seller maintains as
of the last day of each quarter an adjusted Quick Ratio of at least 1.25 to 1.0.
Such payment shall be the "Advance" with respect to such receivable.  Buyer may,
from time to time, in its sole discretion, change the percentage of the Advance.
Upon Buyer's  acceptance of the receivable and payment to Seller of the Advance,
the receivable shall become a "Purchased Receivable." It shall be a condition to
each Advance that (i) all of the  representations  and  warranties  set forth in
Section 6 of this  Agreement  be true and  correct  on and as of the date of the
related Invoice  Transmittal and on and as of the date of such Advance as though
made at and as of each such  date,  and (ii) no Event of Default or any event or
condition that with notice, lapse of time or otherwise would constitute an Event
of Default  shall have  occurred  and be  continuing,  or would result from such
Advance.  Notwithstanding the foregoing,  in no event shall the aggregate amount
of all  Purchased  Receivables  outstanding  at any  time  exceed  FIVE  HUNDRED
THOUSAND DOLLARS ($500,000.00).

      2.3.  EFFECTIVENESS OF SALE TO BUYER. Effective upon Buyer's payment of an
Advance,  and for and in  consideration  therefor  and in  consideration  of the
covenants of this  Agreement,  Seller  hereby  absolutely  sells,  transfers and
assigns to Buyer,  all of  Seller's  right,  title and  interest  in and to each
Purchased  Receivable  and all  monies  due or which may  become  due on or with
respect to such Purchased Receivable.  Buyer shall be the absolute owner of each
Purchased Receivable. Buyer shall have, with respect to any goods related to the
Purchased Receivable,  all the rights and remedies of an unpaid seller under the
California  Uniform  Commercial  Code and other  applicable  law,  including the
rights of replevin, claim and delivery, reclamation and stoppage in transit.

     2.4.  ESTABLISHMENT  OF A  RESERVE.  Upon  the  purchase  by  Buyer of each
Purchased Receivable,  Buyer shall establish a reserve. The reserve shall be the
amount by which the face amount of the Purchased  Receivable exceeds the Advance
on that Purchased Receivable (the "Reserve"); provided, the Reserve with respect
to all Purchased Receivables  outstanding at any one time shall be an amount not
less than 20 (%) percent of the Account Balance at that time and may be set at a
          ------
higher  percentage  at Buyer's  sole  discretion.  The  reserve  shall be a book
balance maintained on the records of Buyer and shall not be a segregated fund.

3.  COLLECTIONS, CHARGES AND REMITTANCES.

     3.1.  COLLECTIONS.  Upon  receipt  by Buyer  of  Collections,  Buyer  shall
promptly credit such  Collections to Seller's  Account Balance on a daily basis;
provided,  that if Seller is in default under this Agreement,  Buyer shall apply
all  Collections to Seller's  Obligations  hereunder in such order and manner as
Buyer may  determine.  If an item of collection is not honored or Buyer does not
receive  good funds for any reason,  the amount shall be included in the Account
Balance as if the  Collections  had not been received and Finance  Charges under
Section 3.2 shall accrue thereon.

     3.2. FINANCE CHARGES. On each Reconciliation Date Seller shall pay to Buyer
a finance charge in an amount equal to 1.75 (%) percent per month of the average
                                       --------
daily Account Balance  outstanding during the applicable  Reconciliation  Period
(the "Finance Charges"). Buyer shall deduct the accrued Finance Charges from the
Reserve as set forth in Section 3.5 below.

     3.3.  ADMINISTRATIVE  FEE. On each  Reconciliation Date Seller shall pay to
Buyer an Administrative Fee equal to 1.00 (%) percent of the face amount of each
                                     --------
Purchased  Receivable  first purchased  during that  Reconciliation  Period (the
"Administrative  Fee").  Buyer  shall  deduct  the  Administrative  Fee from the
Reserve as set forth in Section 3.5 below.

     3.4. ACCOUNTING.  Buyer shall prepare and send to Seller after the close of
business for each  Reconciliation  Period, an accounting of the transactions for
that Reconciliation  Period,  including the amount of all Purchased Receivables,
all Collections,  Adjustments,  Finance Charges, and the Administrative Fee. The
accounting  shall be deemed correct and  conclusive  unless Seller makes written
objection to Buyer within thirty (30) days after the Buyer mails the  accounting
to Seller.

     3.5. REFUND TO SELLER.  Provided that there does not then exist an Event of
Default or any event or condition  that with notice,  lapse of time or otherwise
would  constitute  an Event of Default,  Buyer  shall  refund to Seller by check
after the Reconciliation Date, the amount, if any, which Buyer owes to Seller at
the end of the  Reconciliation  Period  according to the accounting  prepared by
Buyer for that  Reconciliation  Period (the  "Refund").  The Refund  shall be an
amount equal to:
          (A)  (1)  The  Reserve  as of the  beginning  of  that  Reconciliation
                    Period, PLUS


                                   Page 2 of 7
<PAGE>

               (2)  the Reserve created for each Purchased  Receivable purchased
                    during that Reconciliation Period, MINUS
          (B) The total for that Reconciliation Period of:
               (1)  the Administrative Fee;
               (2)  Finance Charges;
               (3)  Adjustments;
               (4)  Repurchase Amounts, to the extent Buyer has agreed to accept
                    payment thereof by deduction from the Refund;
               (5)  the Reserve  for the Account  Balance as of the first day of
                    the   following   Reconciliation   Period  in  the   minimum
                    percentage set forth in Section 2.4 hereof; and
               (6)  all amounts due,  including  professional fees and expenses,
                    as set forth in Section 12 for which oral or written  demand
                    has been made by Buyer to Seller during that  Reconciliation
                    Period  to the  extent  Buyer has  agreed to accept  payment
                    thereof by deduction from the Refund.
In the event the formula set forth in this  Section 3.5 results in an amount due
to Buyer from  Seller,  Seller shall make such payment in the same manner as set
forth in Section  4.3 hereof for  repurchases.  If the formula set forth in this
Section 3.5 results in an amount due to Seller from Buyer, Buyer shall make such
payment by check, subject to Buyer's rights under Section 4.3 and Buyer's rights
of offset and recoupment.

     3.6 FACILITY  FEE. A fully earned,  non-refundable  fee of $5,000.00 is due
upon the execution of this Agreement.

4.  RECOURSE AND REPURCHASE OBLIGATIONS.

     4.1.  RECOURSE.  Buyer's  acquisition of Purchased  Receivables from Seller
shall be with full recourse against Seller. In the event the Obligations  exceed
the amount of Purchased  Receivables and Collateral,  Seller shall be liable for
any deficiency.

     4.2.  SELLER'S  AGREEMENT TO  REPURCHASE.  Seller agrees to pay to Buyer on
demand,  the  full  face  amount,  or  any  unpaid  portion,  of  any  Purchased
Receivable:
          (A)  which remains  unpaid ninety (90) calendar days after the invoice
               date; or
          (B)  which is owed by any  Account  Debtor who has  filed,  or has had
               filed against it, any bankruptcy case, assignment for the benefit
               of creditors,  receivership,  or insolvency proceeding or who has
               become  insolvent  (as  defined in the United  States  Bankruptcy
               Code) or who is  generally  not  paying  its debts as such  debts
               become due; or
          (C)  with  respect to which  there has been any breach of  warranty or
               representation set forth in Section 6 hereof or any breach of any
               covenant contained in this Agreement; or
          (D)  with respect to which the Account  Debtor  asserts any  discount,
               allowance, return, dispute, counterclaim,  offset, defense, right
               of recoupment, right of return, warranty claim, or short payment;
               together with all reasonable attorneys' and professional fees and
               expenses and all court costs incurred by Buyer in collecting such
               Purchased  Receivable  and/or  enforcing  its  rights  under,  or
               collecting  amounts  owed by  Seller  in  connection  with,  this
               Agreement (collectively, the "Repurchase Amount").

     4.3.  SELLER'S PAYMENT OF THE REPURCHASE AMOUNT OR OTHER AMOUNTS DUE BUYER.
When any  Repurchase  Amount or other amount owing to Buyer  becomes due,  Buyer
shall inform Seller of the manner of payment which may be any one or more of the
following  in Buyer's  sole  discretion:  (a) in cash  immediately  upon  demand
therefor;  (b) by delivery of  substitute  invoices  and an Invoice  Transmittal
acceptable to Buyer which shall thereupon become Purchased  Receivables;  (c) by
adjustment to the Reserve pursuant to Section 3.5 hereof;  (d) by deduction from
or offset against the Refund that would  otherwise be due and payable to Seller;
(e) by  deduction  from or offset  against  the amount that  otherwise  would be
forwarded  to Seller in  respect  of any  further  Advances  that may be made by
Buyer; or (f) by any combination of the foregoing as Buyer may from time to time
choose.

     4.4. SELLER'S AGREEMENT TO REPURCHASE ALL PURCHASED  RECEIVABLES.  Upon and
after the occurrence of an Event of Default,  Seller shall,  upon Buyer's demand
(or, in the case of an Event of Default under Section 9(B),  immediately without
notice or demand from  Buyer)  repurchase  all the  Purchased  Receivables  then
outstanding,  or such portion  thereof as Buyer may demand.  Such demand may, at
Buyer's option,  include and Seller shall pay to Buyer  immediately upon demand,
cash in an amount equal to the Advance with respect to each Purchased Receivable
then  outstanding  together  with  all  accrued  Finance  Charges,  Adjustments,
Administrative Fees,  attorney's and professional fees, court costs and expenses
as provided for herein,  and any other  Obligations.  Upon receipt of payment in
full of the Obligations, Buyer shall immediately instruct Account Debtors to pay
Seller directly,  and return to Seller any Refund due to Seller. For the purpose
of calculating any Refund due under this Section only, the  Reconciliation  Date
shall be deemed to be the date Buyer  receives  payment in good funds of all the
Obligations as provided in this Section 4.4.

5. POWER OF  ATTORNEY.  Seller does  hereby  irrevocably  appoint  Buyer and its
successors and assigns as Seller's true and lawful  attorney in fact, and hereby
authorizes Buyer,  regardless of whether there has been an Event of Default, (a)
to sell, assign,  transfer,  pledge,  compromise,  or discharge the whole or any
part of the Purchased  Receivables;  (b) to demand,  collect,  receive, sue, and
give  releases to any Account  Debtor for the monies due or which may become due
upon or with respect to the Purchased Receivables and to compromise,  prosecute,
or defend any  action,  claim,  case or  proceeding  relating  to the  Purchased
Receivables, including the filing of a claim or the voting of such claims in any
bankruptcy case, all in Buyer's name or Seller's name, as Buyer may choose;  (c)
to  prepare,  file and sign  Seller's  name on any  notice,  claim,  assignment,
demand,

                                   Page 3 of 7
<PAGE>

draft,  or notice  of or  satisfaction  of lien or  mechanics'  lien or  similar
document  with  respect to  Purchased  Receivables;  (d) to notify  all  Account
Debtors with respect to the Purchased Receivables to pay Buyer directly;  (e) to
receive,  open,  and dispose of all mail  addressed to Seller for the purpose of
collecting the Purchased Receivables; (f) to endorse Seller's name on any checks
or other forms of payment on the Purchased Receivables; (g) to execute on behalf
of Seller any and all instruments,  documents, financing statements and the like
to perfect Buyer's  interests in the Purchased  Receivables and Collateral;  and
(h) to do all acts and things necessary or expedient, in furtherance of any such
purposes.  If  Buyer  receives  a check  or item  which  is  payment  for both a
Purchased Receivable and another receivable, the funds shall first be applied to
the  Purchased  Receivable  and,  so long as there  does  not  exist an Event of
Default  or an  event  that  with  notice,  lapse  of  time or  otherwise  would
constitute an Event of Default, the excess shall be remitted to Seller. Upon the
occurrence and continuation of an Event of Default, all of the power of attorney
rights granted by Seller to Buyer  hereunder shall be applicable with respect to
all Purchased Receivables and all Collateral.

6.   REPRESENTATIONS, WARRANTIES AND COVENANTS.

     6.1.  RECEIVABLES'  WARRANTIES,  REPRESENTATIONS  AND COVENANTS.  To induce
Buyer to buy  receivables  and to renders its services to Seller,  and with full
knowledge  that the truth and accuracy of the following are being relied upon by
the Buyer in determining whether to accept receivables as Purchased Receivables,
Seller represents,  warrants, covenants and agrees, with respect to each Invoice
Transmittal delivered to Buyer and each receivable described therein, that:
          (A) Seller is the absolute  owner of each  receivable set forth in the
          Invoice  Transmittal  and has full legal right to sell,  transfer  and
          assign such receivables;
          (B) The  correct  amount  of each  receivable  is as set  forth in the
          Invoice Transmittal and is not in dispute;
          (C)  The  payment  of  each  receivable  is not  contingent  upon  the
          fulfillment of any obligation or contract,  past or future and any and
          all  obligations  required of the Seller have been fulfilled as of the
          date of the Invoice Transmittal;
          (D) Each  receivable set forth on the Invoice  Transmittal is based on
          an  actual  sale  and  delivery  of  goods  and/or  services  actually
          rendered,  is presently due and owing to Seller, is not past due or in
          default,  has not been  previously  sold,  assigned,  transferred,  or
          pledged,  and is free of any and all  liens,  security  interests  and
          encumbrances  other than liens,  security interests or encumbrances in
          favor of Buyer or any other  division or affiliate  of Silicon  Valley
          Bank;
          (E) There are no defenses,  offsets,  or counterclaims  against any of
          the  receivables,  and no  agreement  has been  made  under  which the
          Account  Debtor  may  claim  any  deduction  or  discount,  except  as
          otherwise stated in the Invoice Transmittal;
          (F) Each Purchased  Receivable  shall be the property of the Buyer and
          shall be collected  by Buyer,  but if for any reason it should be paid
          to Seller,  Seller shall promptly notify Buyer of such payment,  shall
          hold any  checks,  drafts,  or  monies  so  received  in trust for the
          benefit of Buyer, and shall promptly  transfer and deliver the same to
          the Buyer;
          (G) Buyer shall have the right of  endorsement,  and also the right to
          require  endorsement by Seller, on all payments received in connection
          with each Purchased Receivable and any proceeds of Collateral;
          (H) Seller,  and to Seller's best  knowledge,  each Account Debtor set
          forth in the Invoice Transmittal, are and shall remain solvent as that
          term  is  defined  in  the  United  States  Bankruptcy  Code  and  the
          California  Uniform  Commercial  Code,  and no such Account Debtor has
          filed or had filed against it a voluntary or involuntary  petition for
          relief under the United States Bankruptcy Code;
          (I) Each  Account  Debtor  named on the Invoice  Transmittal  will not
          object to the  payment  for,  or the  quality or the  quantity  of the
          subject  matter  of, the  receivable  and is liable for the amount set
          forth on the Invoice Transmittal;
          (J) Each Account Debtor shall promptly be notified,  after  acceptance
          by Buyer, that the Purchased Receivable has been transferred to and is
          payable to Buyer,  and  Seller  shall not take or permit any action to
          countermand such notification; and
          (K) All receivables  forwarded to and accepted by Buyer after the date
          hereof, and thereby becoming Purchased Receivables,  shall comply with
          each  and  every  one of the  foregoing  representations,  warranties,
          covenants and agreements referred to above in this Section 6.1.

     6.2. ADDITIONAL WARRANTIES,  REPRESENTATIONS AND COVENANTS.  In addition to
the foregoing warranties,  representations and covenants, to induce Buyer to buy
receivables  and to render its  services to Seller,  Seller  hereby  represents,
warrants, covenants and agrees that:
          (A) Seller will not assign,  transfer,  sell, or grant , or permit any
          lien or security  interest in any Purchased  Receivables or Collateral
          to or in favor of any  other  party,  without  Buyer's  prior  written
          consent;
          (B) The Seller's name, form of organization,  chief executive  office,
          and the place where the records  concerning all Purchased  Receivables
          and  Collateral  are  kept  is set  forth  at the  beginning  of  this
          Agreement, Collateral is located only at the location set forth in the
          beginning  of  this  Agreement,  or,  if  located  at  any  additional
          location,  as set forth on a schedule attached to this Agreement,  and
          Seller will give Buyer at least thirty (30) days prior written  notice
          if such name, organization,  chief executive office or other locations
          of  Collateral  or  records   concerning   Purchased   Receivables  or
          Collateral  is  changed  or added  and  shall  execute  any  documents
          necessary to perfect Buyer's interest in the Purchased Receivables and
          the Collateral;
          (C)  Seller  shall  (i)  pay  all  of its  normal  gross  payroll  for
          employees, and all federal and state taxes, as and when due, including
          without  limitation all payroll and withholding  taxes and state sales
          taxes;  (ii)  deliver  at any time and  from  time to time at  Buyer's
          request,  evidence  satisfactory  to Buyer that all such  amounts have
          been paid to the proper taxing authorities;  and (iii) if requested by
          Buyer,  pay  its  payroll  and  related  taxes  through  a bank  or an
          independent payroll service acceptable to Buyer.



                                   Page 4 of 7

<PAGE>

          (D) Seller has not, as of the time Seller delivers to Buyer an Invoice
          Transmittal,  or as of the time Seller accepts any Advance from Buyer,
          filed  a  voluntary  petition  for  relief  under  the  United  States
          Bankruptcy  Code or had filed against it an  involuntary  petition for
          relief;
          (E) If Seller  owns,  holds or has any  interest  in,  any  copyrights
          (whether  registered,  or  unregistered),  patents or trademarks,  and
          licenses of any of the foregoing,  such interest has been disclosed to
          Buyer and is specifically  listed and identified on a schedule to this
          Agreement,  and  Seller  shall  immediately  notify  Buyer  if  Seller
          hereafter obtains any interest in any additional copyrights,  patents,
          trademarks or licenses that are  significant  in value or are material
          to the conduct of its business;
          (F) Seller shall provide Buyer with a Compliance  Certificate (I) on a
          quarterly  basis to be  received  by Buyer  no  later  than the  fifth
          calendar day  following  each  calendar  quarter,  and; (ii) on a more
          frequent or other basis if and as requested by Buyer; and
          (G) Seller shall  provide Buyer with a deferred  revenue  listing upon
          request.

7.  ADJUSTMENTS.  In the  event  of a  breach  of  any  of the  representations,
warranties,  or  covenants  set  forth  in  Section  6.1,  or in the  event  any
Adjustment or dispute is asserted by any Account  Debtor,  Seller shall promptly
advise Buyer and shall,  subject to the Buyer's approval,  resolve such disputes
and advise Buyer of any adjustments. Unless the disputed Purchased Receivable is
repurchased by Seller and the full Repurchase Amount is paid, Buyer shall remain
the absolute owner of any Purchased Receivable which is subject to Adjustment or
repurchase under Section 4.2 hereof,  and any rejected,  returned,  or recovered
personal  property,  with the right to take  possession  thereof at any time. If
such  possession  is not  taken by Buyer,  Seller  is to  resell it for  Buyer's
account at Seller's  expense  with the  proceeds  made  payable to Buyer.  While
Seller retains  possession of said returned  goods,  Seller shall segregate said
goods and mark them "property of Silicon Valley Bank."

8. SECURITY  INTEREST.  To secure the prompt payment and performance to Buyer of
all of the Obligations, Seller hereby grants to Buyer a continuing lien upon and
security  interest in all of Seller's now existing or hereafter  arising  rights
and  interest in the  following,  whether  now owned or  existing  or  hereafter
created,   acquired,  or  arising,  and  wherever  located  (collectively,   the
"Collateral"):
          (A)  All  accounts,  receivables,   contract  rights,  chattel  paper,
          instruments,   documents,  letters  of  credit,  bankers  acceptances,
          drafts, checks, cash, securities,  and general intangibles (including,
          without limitation,  all claims,  causes of action,  deposit accounts,
          guaranties,  rights in and claims under insurance policies  (including
          rights  to  premium  refunds),  rights  to  tax  refunds,  copyrights,
          patents,  trademarks,  rights in and under license agreements, and all
          other intellectual property);
          (B) All  inventory,  including  Seller's  rights  to any  returned  or
          rejected goods,  with respect to which Buyer shall have all the rights
          of any unpaid  seller,  including  the rights of  replevin,  claim and
          delivery, reclamation, and stoppage in transit;
          (C ) All  monies,  refunds and other  amounts  due Seller,  including,
          without limitation, amounts due Seller under this Agreement (including
          Seller's right of offset and recoupment);
          (D) All equipment, machinery, furniture, furnishings, fixtures, tools,
          supplies and motor vehicles;
          (E) All farm products, crops, timber, minerals and the like (including
          oil and gas);
          (F) All accessions to,  substitutions for, and replacements of, all of
          the foregoing;
          (G) All books and records pertaining to all of the foregoing; and
          (H)  All  proceeds  of the  foregoing,  whether  due to  voluntary  or
          involuntary disposition, including insurance proceeds.
          Seller is not authorized to sell, assign, transfer or otherwise convey
any Collateral  without  Buyer's prior written  consent,  except for the sale of
finished  inventory in the Seller's  usual course of business.  Seller agrees to
sign UCC financing  statements,  in a form  acceptable  to Buyer,  and any other
instruments and documents  requested by Buyer to evidence,  perfect,  or protect
the interests of Buyer in the Collateral.  Seller agrees to deliver to Buyer the
originals of all instruments,  chattel paper and documents evidencing or related
to Purchased Receivables and Collateral.

9. DEFAULT.  The occurrence of any one or more of the following shall constitute
an Event of Default hereunder.
          (A) Seller fails to pay any amount owed to Buyer as and when due;
          (B) There shall be  commenced  by or against  Seller any  voluntary or
          involuntary  case  under the United  States  Bankruptcy  Code,  or any
          assignment for the benefit of creditors,  or appointment of a receiver
          or custodian for any of its assets;
          (C) Seller shall  become  insolvent in that its debts are greater than
          the fair value of its assets,  or Seller is  generally  not paying its
          debts as they become due;
          (D) Any  involuntary  lien,  garnishment,  attachment  or the  like is
          issued  against  or  attaches  to  the  Purchased  Receivables  or any
          Collateral;
          (E)  Seller  shall  breach  any  covenant,  agreement,   warranty,  or
          representation  set forth herein, and the same is not cured to Buyer's
          satisfaction within ten (10) days after Buyer has given Seller oral or
          written notice thereof;  provided, that if such breach is incapable of
          being cured it shall constitute an immediate default hereunder;
          (F)  Seller is not in  compliance  with,  or  otherwise  is in default
          under, any term of any document,  instrument or agreement evidencing a
          debt,  obligation or liability of any kind or character of Seller, now
          or hereafter existing,  in favor of Buyer or any division or affiliate
          of Silicon Valley Bank, regardless of whether such debt, obligation or
          liability is direct or indirect, primary or secondary,  joint, several
          or joint and several,  or fixed or  contingent,  together with any and
          all  renewals  and   extensions   of  such  debts,   obligations   and
          liabilities, or any part thereof;
          (G) An event of default shall occur under any guaranty executed by any
          guarantor of the  Obligations of Seller to Buyer under this Agreement,
          or any material  provision of any such  guaranty  shall for any reason
          cease  to be  valid  or  enforceable  or any  such  guaranty  shall be
          repudiated or terminated, including by operation of law;



                                  Page 5 of 7
<PAGE>

          (H) A default  or event of default  shall  occur  under any  agreement
          between  Seller and any  creditor of Seller  that has  entered  into a
          subordination  agreement  with  Buyer;  or

          (I) Any creditor that has entered into a subordination  agreement with
          Buyer  shall  breach  any of the  terms  of or not  comply  with  such
          subordination agreement.

10.  REMEDIES UPON  DEFAULT.  Upon the  occurrence  of an Event of Default,  (1)
without  implying  any  obligation  to buy  receivables,  Buyer may cease buying
receivables or extending any financial  accommodations  to Seller;  (2) all or a
portion of the Obligations  shall be, at the option of and upon demand by Buyer,
or with respect to an Event of Default described in Section 9(B),  automatically
and without notice or demand,  due and payable in full; and (3) Buyer shall have
and may  exercise  all the rights and remedies  under this  Agreement  and under
applicable  law,  including the rights and remedies of a secured party under the
California  Uniform  Commercial Code, all the power of attorney rights described
in Section 5 with respect to all Collateral,  and the right to collect,  dispose
of,  sell,  lease,  use,  and realize  upon all  Purchased  Receivables  and all
Collateral in any commercial  reasonable manner. Seller and Buyer agree that any
notice of sale  required to be given to Seller shall be deemed to be  reasonable
if given five (5) days prior to the date on or after which the sale may be held.
In the event  that the  Obligations  are  accelerated  hereunder,  Seller  shall
repurchase all of the Purchased Receivables as set forth in Section 4.4.

11. ACCRUAL OF INTEREST. If any amount owed by Seller hereunder is not paid when
due, including,  without  limitation,  amounts due under Section 3.5, Repurchase
Amounts,  amounts due under Section 12, and any other Obligations,  such amounts
shall  bear  interest  at a per annum  rate  equal to the per annum  rate of the
Finance  Charges until the earlier of (i) payment in good funds or (ii) entry of
a final  judgment  thereof,  at which  time the  principal  amount  of any money
judgment remaining unsatisfied shall accrue interest at the highest rate allowed
by applicable law.

12.  FEES,  COSTS AND  EXPENSES;  INDEMNIFICATION.  The Seller will pay to Buyer
immediately  upon  demand  all  fees,  costs  and  expenses  (including  fees of
attorneys and  professionals  and their costs and expenses) that Buyer incurs or
may from  time to time  impose  in  connection  with any of the  following:  (a)
preparing, negotiating, administering, and enforcing this Agreement or any other
agreement executed in connection herewith, including any amendments,  waivers or
consents in connection with any of the foregoing,  (b) any litigation or dispute
(whether instituted by Buyer, Seller or any other person) in any way relating to
the Purchased Receivables, the Collateral, this Agreement or any other agreement
executed in connection  herewith or therewith,  (d) enforcing any rights against
Seller or any guarantor,  or any Account Debtor, (e) protecting or enforcing its
interest in the Purchased  Receivables  or the  Collateral,  (f)  collecting the
Purchased  Receivables and the Obligations,  and (g) the representation of Buyer
in  connection  with any  bankruptcy  case or  insolvency  proceeding  involving
Seller,  any Purchased  Receivable,  the Collateral,  any Account Debtor, or any
guarantor.  Seller shall  indemnify and hold Buyer harmless from and against any
and all claims, actions, damages, costs, expenses, and liabilities of any nature
whatsoever arising in connection with any of the foregoing.

13. SEVERABILITY,  WAIVER, AND CHOICE OF LAW. In the event that any provision of
this  Agreement  is deemed  invalid  by reason of law,  this  Agreement  will be
construed as not  containing  such  provision and the remainder of the Agreement
shall remain in full force and effect.  Buyer retains all of its rights, even if
it makes an  Advance  after an Event of  Default.  If Buyer  waives  an Event of
Default,  it may enforce a later Event of Default.  Any consent or waiver under,
or amendment of, this Agreement must be in writing. Nothing contained herein, or
any action  taken or not taken by Buyer at any time,  shall be  construed at any
time to be indicative of any  obligation or  willingness on the part of Buyer to
amend  this  Agreement  or to grant to Seller  any  waivers  or  consents.  This
Agreement has been transmitted by Seller to Buyer at Buyer's office in the State
of  California  and has been  executed  and  accepted  by Buyer in the  State of
California.  This Agreement  shall be governed by and  interpreted in accordance
with the internal laws of the State of California.

14. ACCOUNT COLLECTION  SERVICES.  Certain Account Debtors may require or prefer
that all of Seller's  receivables be paid to the same address  and/or party,  or
Seller and Buyer may agree that all receivables  with respect to certain Account
Debtors  be paid to one  party.  In such  event  Buyer and Seller may agree that
Buyer  shall  collect  all  receivables  whether  owned by  Seller  or Buyer and
(provided  that there does not then exist an Event of Default or event that with
notice,  lapse or time or otherwise  would  constitute an Event of Default,  and
subject to Buyer's rights in the Collateral) Buyer agrees to remit to Seller the
amount of the  receivables  collections  it receives with respect to receivables
other than  Purchased  Receivables.  It is understood  and agreed by Seller that
this Section does not impose any  affirmative  duty on Buyer to do any act other
than to turn  over  such  amounts.  All such  receivables  and  collections  are
Collateral and in the event of Seller's default  hereunder,  Buyer shall have no
duty to remit  collections of Collateral  and may apply such  collections to the
obligations  hereunder  and Buyer shall have the rights of a secured party under
the California Uniform Commercial Code.

15. NOTICES.  All notices shall be given to Buyer and Seller at the addresses or
faxes set forth on the first page of this  Agreement and shall be deemed to have
been  delivered  and  received:  (a) if mailed,  three (3)  calendar  days after
deposited in the United States mail, first class, postage pre-paid,  (b) one (1)
calendar day after deposit with an overnight mail or messenger  service;  or (c)
on the same date of confirmed  transmission if sent by hand delivery,  telecopy,
telefax or telex.

16. JURY TRIAL.  SELLER AND BUYER EACH HEREBY (a) WAIVE THEIR RESPECTIVE  RIGHTS
TO A JURY TRIAL ON ANY CLAIM OR ACTION ARISING OUT OF OR IN CONNECTION WITH THIS
AGREEMENT,  ANY  RELATED  AGREEMENTS,  OR ANY OF THE  TRANSACTIONS  CONTEMPLATED
HEREBY OR THEREBY; (b) RECOGNIZE AND AGREE THAT THE FOREGOING WAIVER CONSTITUTES
A MATERIAL INDUCEMENT FOR IT TO ENTER INTO THIS AGREEMENT; AND (c) REPRESENT AND
WARRANT  THAT IT HAS  REVIEWED  THIS  WAIVER,  HAS  DETERMINED  FOR  ITSELF  THE
NECESSITY




                                  Page 6 of 7
<PAGE>

TO REVIEW THE SAME WITH ITS LEGAL COUNSEL,  AND KNOWINGLY AND VOLUNTARILY WAIVES
ALL RIGHTS TO A JURY TRIAL.

17. TERM AND  TERMINATION.  The term of this Agreement shall be for one (1) year
from the date hereof,  and from year to year  thereafter  unless  terminated  in
writing  by Buyer or  Seller.  Seller  and  Buyer  shall  each have the right to
terminate  this  Agreement  at any  time.  Notwithstanding  the  foregoing,  any
termination of this Agreement shall not affect Buyer's security  interest in the
Collateral  and  Buyer's  ownership  of  the  Purchased  Receivables,  and  this
Agreement  shall  continue  to be  effective,  and Buyer's  rights and  remedies
hereunder shall survive such  termination,  until all transactions  entered into
and Obligations incurred hereunder or in connection herewith have been completed
and satisfied in full.

18. TITLES AND SECTION HEADINGS. The titles and section headings used herein are
for convenience only and shall not be used in interpreting this Agreement.


                                  Page 7 of 7
<PAGE>


19. OTHER  AGREEMENTS.  The terms and  provisions  of this  Agreement  shall not
adversely  affect  the rights of Buyer or any other  division  or  affiliate  of
Silicon Valley Bank under any other document, instrument or agreement. The terms
of such other  documents,  instruments and agreements shall remain in full force
and effect  notwithstanding  the execution of this Agreement.  In the event of a
conflict  between any provision of this Agreement and any provision of any other
document,  instrument or agreement  between Seller on the one hand, and Buyer or
any other division or affiliate of Silicon Valley Bank on the other hand,  Buyer
shall  determine in its sole  discretion  which  provision  shall apply.  Seller
acknowledges  specifically that any security  agreements,  liens and/or security
interests currently securing payment of any obligations of Seller owing to Buyer
or any other division or affiliate of Silicon  Valley Bank also secure  Seller's
obligations  under  this  Agreement,  and are valid and  subsisting  and are not
adversely affected by execution of this Agreement.  Seller further  acknowledges
that (a) any collateral  under other  outstanding  security  agreements or other
documents between Seller and Buyer or any other division or affiliate of Silicon
Valley Bank secures the  obligations  of Seller under this  Agreement  and (b) a
default  by Seller  under  this  Agreement  constitutes  a default  under  other
outstanding  agreements  between  Seller  and  Buyer or any  other  division  or
affiliate of Silicon Valley Bank.

     IN WITNESS  WHEREOF,  Seller and Buyer have executed this  Agreement on the
day and year above written.

SELLER:  BIO-IMAGING TECHNOLOGIES, INC.


By Robert J. Phillips
   ------------------
Title Vice President and Chief Financial Officer
      ------------------------------------------



BUYER:  SILICON VALLEY BANK


By David Reich
   ------------------
Title Vice President
      ---------------


<PAGE>


                                   EXHIBIT "A"

                  TO FINANCING STATEMENT AND SECURITY AGREEMENT

This FINANCING  STATEMENT and SECURITY  AGREEMENT  covers the following types or
items of property (in  addition  to, and without  limiting the types of property
set forth on page 1 hereof):

A)   All accounts,  receivables,  contract rights,  chattel paper,  instruments,
     documents,  letters of credit,  bankers acceptances,  drafts, checks, cash,
     securities,  deposit accounts, and general intangibles (including,  without
     limitation, all claims, causes of action, guaranties,  rights in and claims
     under insurance policies  (including rights to premium refunds),  rights to
     tax refunds, copyrights,  patents, trademarks,  rights in and under license
     agreements, and all other intellectual property);

B)   All inventory, including Seller's rights to any returned or rejected goods,
     with respect to which Buyer shall have all the rights of any unpaid seller,
     including  the rights of replevin,  claim and  delivery,  reclamation,  and
     stoppage in transit;

C)   All monies,  refunds  and other  amounts  due  Seller,  including,  without
     limitation,  amounts due Seller under this  Agreement  (including  Seller's
     right of offset and recoupment);

D)   All equipment, machinery, furniture, furnishings, fixtures, tools, supplies
     and motor vehicles;

E)   All farm products,  crops, timber, minerals and the like (including oil and
     gas);

F)   All  accessions  to,  substitutions  for, and  replacements  of, all of the
     foregoing;

G)   All books and records pertaining to all of the foregoing; and

H)   All proceeds of the  foregoing,  whether due to  voluntary  or  involuntary
     disposition, including insurance proceeds.






INTITALS
        --------------


<PAGE>


                               SILICON VALLEY BANK
                                3003 Tasman Drive
                          Santa Clara, California 95054
                       (408) 654-1000 - Fax (408) 980-6410

                            CERTIFICATION of OFFICERS

      The undersigned, being all the officers of Bio-Imaging Technologies, Inc.,
a Delaware  corporation  (the  "Corporation"),  hereby certify to Silicon Valley
Bank ("SVB") that:

      1. The correct name of the Corporation is Bio-Imaging Technologies,  Inc.,
as set forth in the Articles of Incorporation.

      2. The Corporation was incorporated on                         , under the
                                             ------------------------
laws of the State of Delaware, and is in good standing under such laws.

      3. The  Corporation's  place of business and chief executive  office being
the place at which the Corporation maintains its books and records pertaining to
accounts,   accounts  receivables,   contract  rights,  chattel  paper,  general
intangibles, instruments, documents, inventory, and equipment, is located at:

            830 BEAR TAVERN ROAD
            WEST TRENTON, NEW JERSEY 08628

      4.  The  Corporation  has  other  places  of  business  at  the  following
addressees:

      None



      5. There is no provision in the Certificate of Incorporation,  Articles of
Incorporation,  or Bylaws of the Corporation, or in the laws of the State of its
incorporation,  requiring any vote or consent of  shareholders  to authorize the
sale of  receivables  or the grant of a security  interest  in any assets of the
Corporation.  Such power is vested  exclusively  in the  Corporation's  Board of
Directors.

      6. The  officers  of the  Corporation,  and their  respective  titles  and
signatures are as follows:

      PRESIDENT:

           --------------------------------------------------------------------
                                   (Signature)

      VICE PRESIDENT:

           --------------------------------------------------------------------
                                   (Signature)

      SECRETARY:

           --------------------------------------------------------------------
                                   (Signature)

      TREASURER:

           --------------------------------------------------------------------
                                   (Signature)

      OTHER OFFICER:
      TITLE:

           --------------------------------------------------------------------
                                   (Signature)
<PAGE>

      7. Except as indicated in this paragraph 7, each of the officers listed in
paragraph  6  has  signatory  powers  with  respect  to  all  the  Corporation's
transactions with SVB. Explanation of exceptions:

      8. The  undersigned  shall give SVB prompt written notice of any change or
amendment  with respect to any of the  foregoing.  Until such written  notice is
received  by SVB,  SVB  shall be  entitled  to rely  upon the  foregoing  in all
respects.

      IN WITNESS WHEREOF,  the undersigned  have executed this  Certification of
Officers on 12/22/1999.
            ----------

PRESIDENT:
                 ---------------------------------------------------------------
VICE PRESIDENT:
                 ---------------------------------------------------------------
SECRETARY:
                 ---------------------------------------------------------------
TREASURER:
                 ---------------------------------------------------------------





<PAGE>



                               SILICON VALLEY BANK
                                3003 Tasman Drive
                          Santa Clara, California 95054
                       (408) 654-1000 - Fax (408) 980-6410

                      SECRETARY'S CERTIFICATE OF RESOLUTION

      The  undersigned,  as  Secretary  of  Bio-Imaging  Technologies,  Inc.,  a
Delaware  corporation  (the  "Corporation"),  hereby certifies to Silicon Valley
Bank that at a meeting duly convened at which a quorum was present the following
resolutions  were adopted by the Board of Directors of the  Corporation and that
such  resolutions have not been modified,  amended,  or rescinded in any respect
and are in full force and effect as of today's date.

      RESOLVED,  that this  corporation be and hereby is authorized to sell this
corporation's  accounts  receivable to Silicon Valley Bank, and to grant Silicon
Valley Bank a security interest in this corporation's assets, including, without
limitation,  accounts,  accounts  receivable,  contract  rights,  chattel paper,
general  intangibles,   instruments,   documents,  letters  of  credit,  drafts,
inventory and equipment,  presently owned or hereafter acquired and proceeds and
products  of the  foregoing  (the "  Collateral,"  as  defined  in the  Accounts
Receivable Purchase Agreement).

      RESOLVED,  that this  corporation be and hereby is authorized and directed
to  execute  and  deliver  certain  agreements  in  connection  with the sale of
receivables,  and granting of security  interests in the  Collateral  to Silicon
Valley Bank  including,  without  limitations,  a Accounts  Receivable  Purchase
Agreement and UCC-1 financing statement.

      RESOLVED,   that  the  following   named  officers  of  this   corporation
("Authorized  Officers") be, and any of them hereby are, authorized,  empowered,
and  directed to execute  and  deliver to Silicon  Valley Bank on behalf of this
corporation  all  such  further  agreements  and  instruments  as may be  deemed
necessary or advisable in order to fully  effectuate  the purposes and intent of
the foregoing resolutions.

      Print Names of Authorized Officers:                   Title:


- -----------------------------------------------     ----------------------------

- -----------------------------------------------     ----------------------------

- -----------------------------------------------     ----------------------------

- -----------------------------------------------     ----------------------------

- -----------------------------------------------     ----------------------------

- -----------------------------------------------     ----------------------------

            RESOLVED,   that  the  Secretary  or  Assistant  Secretary  of  this
corporation  be, and hereby is authorized,  empowered and directed to certify to
the passage of the foregoing resolutions under the seal of this corporation.

IN WITNESS  WHEREOF,  the  undersigned has duly executed this  Certificate  this
Twenty Second day of December 1999.


                      --------------------------------------------------------
                         Signature

                         Secretary of BIO-IMAGING TECHNOLOGIES, INC.


<PAGE>


                               CONSENT AND RELEASE

Silicon  Valley  Bank  sincerely  appreciates  your  business  and would like to
publicize your Company recently joining our "family".  In order to do so, kindly
complete the following and return to us.

Bio-Imaging Technologies, Inc. ("Client") consents to and releases Silicon
Valley Bank ("Bank") from any liability in its use of (check all that apply):

                  Company Name
                                           ---------
                  Individual Name
                                           ---------
                  Quotation
                                           ---------
                  Photograph
                                           ---------
                  Client Reference
                                           ---------
                  Type of Credit Facility
                                           ---------
                  Amount of Credit Facility
                                           ---------

in Bank's written and oral presentations,  advertising and promotional materials
and Internet Web site.


Client Name:

Bio-Imaging Technologies, Inc.


- --------------------------
Signature

- --------------------------
Name and Title

- --------------------------
Date





                    CONSENT OF INDEPENDENT PUBLIC ACCOUNTANTS



As independent  public  accountants,  we hereby consent to the  incorporation by
reference  of our report dated  December 22, 1999  included in this Form 10-KSB,
into  Bio-Imaging   Technologies,   Inc.  and  subsidiaries'   previously  filed
Registration Statements on Form S-8 (File Nos. 33-90412,  33-74152 and 33-22661)
and on Form S-3 (File Nos. 33-75370 and 33-25477).



                                             /s/Arthur Andersen LLP
                                             ARTHUR ANDERSEN LLP


Roseland, New Jersey

December 22, 1999





<TABLE> <S> <C>


<ARTICLE>                     5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL  INFORMATION EXTRACTED FROM THE AUDITED
FINANCIAL STATEMENTS INCLUDED IN THE REGISTRANT'S FORM 10-KSB FOR THE YEAR ENDED
SEPTEMBER  30,  1999 AND IS  QUALIFIED  IN ITS  ENTIRETY  BY  REFERENCE  TO SUCH
FINANCIAL STATEMENTS.
</LEGEND>
<CIK>                         0000822418
<NAME>                        Bio-Imaging Technologies, Inc.
<MULTIPLIER>                                   1
<CURRENCY>                                     U.S. Dollars

<S>                             <C>
<PERIOD-TYPE>                   YEAR
<FISCAL-YEAR-END>                              SEP-30-1999
<PERIOD-START>                                 OCT-01-1998
<PERIOD-END>                                   SEP-30-1999
<EXCHANGE-RATE>                                1
<CASH>                                         412,903
<SECURITIES>                                   0
<RECEIVABLES>                                  1,302,746
<ALLOWANCES>                                   65,000
<INVENTORY>                                    0
<CURRENT-ASSETS>                               1,788,776
<PP&E>                                         4,611,404
<DEPRECIATION>                                 3,431,150
<TOTAL-ASSETS>                                 3,148,654
<CURRENT-LIABILITIES>                          1,000,983
<BONDS>                                        81,511
                          0
                                    104
<COMMON>                                       1,944
<OTHER-SE>                                     2,064,112
<TOTAL-LIABILITY-AND-EQUITY>                   3,148,654
<SALES>                                        0
<TOTAL-REVENUES>                               4,349,079
<CGS>                                          0
<TOTAL-COSTS>                                  2,660,659
<OTHER-EXPENSES>                               2,402,639
<LOSS-PROVISION>                               0
<INTEREST-EXPENSE>                             (8,760)
<INCOME-PRETAX>                                (705,459)
<INCOME-TAX>                                   0
<INCOME-CONTINUING>                            (705,459)
<DISCONTINUED>                                 0
<EXTRAORDINARY>                                0
<CHANGES>                                      0
<NET-INCOME>                                   (705,459)
<EPS-BASIC>                                  (0.10)<F1>
<EPS-DILUTED>                                  (0.10)<F2>
<FN>
<F1>  This amount represents Basic Earnings per Share in accordance with the
      requirements of Statement of Financial Accounting Standards No. 128 -
      "Earnings per Share."
<F2>  This amount represents Diluted Earnings per Share in accordance with the
      requirements of Statement of Financial Accounting Standards No. 128 -
      "Earnings per Share."
</FN>


</TABLE>


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