<PAGE> PAGE 1
000 A000000 12/31/95
000 C000000 0000823483
000 D000000 N
000 E000000 NF
000 F000000 Y
000 G000000 N
000 H000000 N
000 I000000 3.0.a
000 J000000 U
001 A000000 OPPENHEIMER MAIN STREET FUNDS, INC.
001 B000000 811-5360
001 C000000 3037432869
002 A000000 3410 SOUTH GALENA STREET
002 B000000 DENVER
002 C000000 C
002 D010000 80231
003 000000 N
004 000000 N
005 000000 N
006 000000 N
007 A000000 Y
007 B000000 2
007 C010100 1
007 C010200 2
007 C020200 OPPENHEIMER MAIN STREET INCOME & GROWTH FUND
007 C030200 N
007 C010300 3
007 C010400 4
007 C010500 5
007 C020500 OPP. MAIN STREET CALIFORNIA TAX-EXEMPT FUND
007 C030500 N
007 C010600 6
007 C010700 7
007 C010800 8
007 C010900 9
007 C011000 10
008 A00AA01 OPPENHEIMERFUNDS, INC.
008 B00AA01 A
008 C00AA01 801-8253
008 D01AA01 NEW YORK
008 D02AA01 NY
008 D03AA01 10048
008 D04AA01 0203
011 A00AA01 OPPENHEIMERFUNDS DISTRIBUTOR, INC.
011 B00AA01 8-22992
011 C01AA01 NEW YORK
011 C02AA01 NY
011 C03AA01 10048
011 C04AA01 0203
012 A00AA01 OPPENHEIMERFUNDS SERVICES
012 B00AA01 84-907
<PAGE> PAGE 2
012 C01AA01 DENVER
012 C02AA01 CO
012 C03AA01 80201
018 00AA00 Y
019 A00AA00 Y
019 B00AA00 42
019 C00AA00 OPPENHEIMR
020 A000001 FIRST CHICAGO CAPITAL MARKET
020 B000001 36-3595942
020 C000001 19068
020 A000002 MERRILL LYNCH, PIERCE, FENNER & SMITH, INC.
020 B000002 13-5674085
020 C000002 999
020 A000003 GOLDMAN, SACHS & CO.
020 B000003 13-5108880
020 C000003 822
020 A000004 MORGAN STANLEY & CO., INC.
020 B000004 13-2655998
020 C000004 776
020 A000005 SALOMON BROTHERS, INC.
020 B000005 13-3082694
020 C000005 545
020 A000006 SMITH BARNEY, HARRIS UPHAM & CO., INC.
020 B000006 13-3371860
020 C000006 502
020 A000007 FIRST BOSTON CORP. (THE)
020 B000007 13-5659485
020 C000007 378
020 A000008 DONALDSON, LUFKIN & JENRETTE SECURITIES CORP.
020 B000008 13-2741729
020 C000008 359
020 A000009 BEAR SECURITIES CORP.
020 B000009 13-3299429
020 C000009 316
020 A000010 PAINEWEBBER, INC.
020 B000010 13-2638166
020 C000010 303
021 000000 28288
022 A000001 MERRILL LYNCH, PIERCE, FENNER, & SMITH, INC.
022 B000001 13-5674085
022 C000001 323292
022 D000001 35899
022 A000002 MORGAN STANLEY & CO., INC.
022 B000002 13-2655998
022 C000002 163982
022 D000002 174816
022 A000003 LEHMAN BROTHERS, INC.
022 B000003 13-2518466
022 C000003 249680
022 D000003 49478
022 A000004 SALOMON BROTHERS, INC.
<PAGE> PAGE 3
022 B000004 13-3082694
022 C000004 160297
022 D000004 75019
022 A000005 DONALDSON, LUFKIN & JENRETTE SECURITIES CORP.
022 B000005 13-2741729
022 C000005 83998
022 D000005 50485
022 A000006 BEAR SECURITIES CORP.
022 B000006 13-3299429
022 C000006 53262
022 D000006 67019
022 A000007 PAINEWEBBER, INC.
022 B000007 13-2638166
022 C000007 66107
022 D000007 37419
022 A000008 SMITH BARNEY, HARRIS UPHAM & CO., INC.
022 B000008 13-3371860
022 C000008 60959
022 D000008 42033
022 A000009 GOLDMAN, SACHS & CO.
022 B000009 13-5108880
022 C000009 74535
022 D000009 28320
022 A000010 FIRST BOSTON CORP. (THE)
022 B000010 13-5659485
022 C000010 73748
022 D000010 25243
023 C000000 3747689
023 D000000 1281891
077 A000000 N
078 000000 N
028 A010200 157388
028 A020200 2
028 A030200 0
028 A040200 66236
028 B010200 178043
028 B020200 1
028 B030200 0
028 B040200 59023
028 C010200 167157
028 C020200 10904
028 C030200 0
028 C040200 44719
028 D010200 184678
028 D020200 -6
028 D030200 0
028 D040200 61893
028 E010200 174052
028 E020200 0
028 E030200 0
028 E040200 43869
<PAGE> PAGE 4
028 F010200 178179
028 F020200 26791
028 F030200 0
028 F040200 54263
028 G010200 1039497
028 G020200 37692
028 G030200 0
028 G040200 330003
028 H000200 876504
029 000200 Y
030 A000200 14523
030 B000200 5.75
030 C000200 0.00
031 A000200 3627
031 B000200 0
032 000200 10896
033 000200 0
034 000200 Y
035 000200 1058
036 A000200 N
036 B000200 0
042 A000200 0
042 B000200 0
042 C000200 0
042 D000200 100
042 E000200 0
042 F000200 0
042 G000200 0
042 H000200 0
043 000200 9629
044 000200 0
055 A000200 Y
055 B000200 N
056 000200 N
057 000200 N
062 A000200 N
062 B000200 0.0
062 C000200 0.0
062 D000200 0.0
062 E000200 0.0
062 F000200 0.0
062 G000200 0.0
062 H000200 0.0
062 I000200 0.0
062 J000200 0.0
062 K000200 0.0
062 L000200 0.0
062 M000200 0.0
062 N000200 0.0
062 O000200 0.0
062 P000200 0.0
<PAGE> PAGE 5
062 Q000200 0.0
062 R000200 0.0
071 A000200 1670117
071 B000200 1264299
071 C000200 3048626
071 D000200 42
072 A000200 6
072 B000200 22855
072 C000200 27842
072 D000200 0
072 E000200 0
072 F000200 8516
072 G000200 0
072 H000200 0
072 I000200 3830
072 J000200 12
072 K000200 539
072 L000200 193
072 M000200 22
072 N000200 284
072 O000200 0
072 P000200 0
072 Q000200 0
072 R000200 15
072 S000200 20
072 T000200 9629
072 U000200 0
072 V000200 0
072 W000200 344
072 X000200 23404
072 Y000200 0
072 Z000200 27293
072AA000200 185211
072BB000200 95993
072CC010200 303441
072CC020200 0
072DD010200 19832
072DD020200 5283
072EE000200 11932
073 A010200 0.2251
073 A020200 0.1413
073 B000200 0.0784
073 C000200 0.0000
074 A000200 92
074 B000200 452800
074 C000200 212438
074 D000200 210347
074 E000200 238438
074 F000200 3012748
074 G000200 0
074 H000200 0
<PAGE> PAGE 6
074 I000200 0
074 J000200 1214
074 K000200 0
074 L000200 29268
074 M000200 73
074 N000200 4157418
074 O000200 4801
074 P000200 155
074 Q000200 0
074 R010200 0
074 R020200 0
074 R030200 1901
074 R040200 9210
074 S000200 0
074 T000200 4141351
074 U010200 91810
074 U020200 41106
074 V010200 26.89
074 V020200 26.79
074 W000200 0.0000
074 X000200 364934
074 Y000200 29575
075 A000200 0
075 B000200 3587904
076 000200 0.00
028 A010500 371
028 A020500 254
028 A030500 0
028 A040500 435
028 B010500 394
028 B020500 255
028 B030500 0
028 B040500 731
028 C010500 479
028 C020500 253
028 C030500 0
028 C040500 889
028 D010500 248
028 D020500 255
028 D030500 0
028 D040500 822
028 E010500 969
028 E020500 253
028 E030500 0
028 E040500 586
028 F010500 217
028 F020500 302
028 F030500 0
028 F040500 715
028 G010500 2678
028 G020500 1572
<PAGE> PAGE 7
028 G030500 0
028 G040500 4178
028 H000500 2582
029 000500 Y
030 A000500 58
030 B000500 4.75
030 C000500 0.00
031 A000500 17
031 B000500 0
032 000500 41
033 000500 0
034 000500 Y
035 000500 0
036 A000500 N
036 B000500 0
042 A000500 0
042 B000500 0
042 C000500 0
042 D000500 100
042 E000500 0
042 F000500 0
042 G000500 0
042 H000500 0
043 000500 16
044 000500 0
055 A000500 Y
055 B000500 N
056 000500 N
057 000500 N
062 A000500 Y
062 B000500 0.0
062 C000500 0.0
062 D000500 0.0
062 E000500 0.0
062 F000500 0.0
062 G000500 0.0
062 H000500 0.0
062 I000500 0.0
062 J000500 0.0
062 K000500 0.0
062 L000500 0.0
062 M000500 0.0
062 N000500 0.0
062 O000500 98.2
062 P000500 0.0
062 Q000500 0.0
062 R000500 0.0
063 A000500 0
063 B000500 21.1
064 A000500 Y
064 B000500 N
<PAGE> PAGE 8
070 A010500 Y
070 A020500 N
070 B010500 N
070 B020500 N
070 C010500 Y
070 C020500 N
070 D010500 N
070 D020500 N
070 E010500 Y
070 E020500 N
070 F010500 N
070 F020500 N
070 G010500 Y
070 G020500 N
070 H010500 N
070 H020500 N
070 I010500 N
070 I020500 N
070 J010500 Y
070 J020500 N
070 K010500 Y
070 K020500 N
070 L010500 N
070 L020500 N
070 M010500 N
070 M020500 N
070 N010500 Y
070 N020500 N
070 O010500 Y
070 O020500 N
070 P010500 Y
070 P020500 Y
070 Q010500 N
070 Q020500 N
070 R010500 N
070 R020500 N
071 A000500 13395
071 B000500 11758
071 C000500 80923
071 D000500 15
072 A000500 6
072 B000500 2697
072 C000500 0
072 D000500 0
072 E000500 0
072 F000500 166
072 G000500 0
072 H000500 0
072 I000500 28
072 J000500 1
072 K000500 10
<PAGE> PAGE 9
072 L000500 22
072 M000500 0
072 N000500 3
072 O000500 0
072 P000500 0
072 Q000500 0
072 R000500 3
072 S000500 1
072 T000500 16
072 U000500 0
072 V000500 0
072 W000500 5
072 X000500 255
072 Y000500 0
072 Z000500 2442
072AA000500 178
072BB000500 362
072CC010500 3500
072CC020500 0
072DD010500 2367
072DD020500 76
072EE000500 74
073 A010500 0.3680
073 A020500 0.3050
073 B000500 0.0111
073 C000500 0.0000
074 A000500 662
074 B000500 0
074 C000500 0
074 D000500 82612
074 E000500 0
074 F000500 0
074 G000500 0
074 H000500 0
074 I000500 0
074 J000500 0
074 K000500 0
074 L000500 1764
074 M000500 8
074 N000500 85046
074 O000500 563
074 P000500 2
074 Q000500 0
074 R010500 0
074 R020500 0
074 R030500 0
074 R040500 386
074 S000500 0
074 T000500 84095
074 U010500 6407
074 U020500 280
<PAGE> PAGE 10
074 V010500 12.58
074 V020500 12.56
074 W000500 0.0000
074 X000500 2323
074 Y000500 0
075 A000500 0
075 B000500 82108
076 000500 0.00
SIGNATURE GEORGE C. BOWEN
TITLE TREASURER
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000823483
<NAME> OPPENHEIMER MAIN STREET INCOME & GROWTH FUND - CLASS A
<SERIES>
<NUMBER> 2
<NAME> OPPENHEIMER MAIN STREET FUNDS, INC.
<S> <C>
<PERIOD-TYPE> 6-MOS
<FISCAL-YEAR-END> JUN-30-1996
<PERIOD-START> JUL-01-1995
<PERIOD-END> DEC-31-1995
<INVESTMENTS-AT-COST> 3521984011
<INVESTMENTS-AT-VALUE> 4126771550
<RECEIVABLES> 30481865
<ASSETS-OTHER> 72723
<OTHER-ITEMS-ASSETS> 91637
<TOTAL-ASSETS> 4157417775
<PAYABLE-FOR-SECURITIES> 4800567
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 11266754
<TOTAL-LIABILITIES> 16067321
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 3462320588
<SHARES-COMMON-STOCK> 91810063
<SHARES-COMMON-PRIOR> 79933834
<ACCUMULATED-NII-CURRENT> 555009
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 74666817
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 603808040
<NET-ASSETS> 2468379670
<DIVIDEND-INCOME> 27842101
<INTEREST-INCOME> 22855347
<OTHER-INCOME> 0
<EXPENSES-NET> 23404110
<NET-INVESTMENT-INCOME> 27293338
<REALIZED-GAINS-CURRENT> 89217459
<APPREC-INCREASE-CURRENT> 303441041
<NET-CHANGE-FROM-OPS> 419951838
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> 19831845
<DISTRIBUTIONS-OF-GAINS> 7115143
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 19650480
<NUMBER-OF-SHARES-REDEEMED> 8745247
<SHARES-REINVESTED> 970996
<NET-CHANGE-IN-ASSETS> 1127323067
<ACCUMULATED-NII-PRIOR> 1145174
<ACCUMULATED-GAINS-PRIOR> (2618874)
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 8515990
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 23404110
<AVERAGE-NET-ASSETS> 2204524000
<PER-SHARE-NAV-BEGIN> 24.07
<PER-SHARE-NII> .22
<PER-SHARE-GAIN-APPREC> 2.90
<PER-SHARE-DIVIDEND> .22
<PER-SHARE-DISTRIBUTIONS> .08
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 26.89
<EXPENSE-RATIO> 1.00
<AVG-DEBT-OUTSTANDING> 0
<AVG-DEBT-PER-SHARE> 0
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000823483
<NAME> OPPENHEIMER MAIN STREET INCOME & GROWTH - CLASS B
<SERIES>
<NUMBER> 2
<NAME> OPPENHEIMER MAIN STREET FUNDS, INC.
<S> <C>
<PERIOD-TYPE> 6-MOS
<FISCAL-YEAR-END> JUN-30-1996
<PERIOD-START> JUL-01-1995
<PERIOD-END> DEC-31-1995
<INVESTMENTS-AT-COST> 3521984011
<INVESTMENTS-AT-VALUE> 4126771550
<RECEIVABLES> 30481865
<ASSETS-OTHER> 72723
<OTHER-ITEMS-ASSETS> 91637
<TOTAL-ASSETS> 4157417775
<PAYABLE-FOR-SECURITIES> 4800567
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 11266754
<TOTAL-LIABILITIES> 16067321
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 3462320588
<SHARES-COMMON-STOCK> 41105695
<SHARES-COMMON-PRIOR> 26189101
<ACCUMULATED-NII-CURRENT> 555009
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 74666817
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 603808040
<NET-ASSETS> 1101140232
<DIVIDEND-INCOME> 27842101
<INTEREST-INCOME> 22855347
<OTHER-INCOME> 0
<EXPENSES-NET> 23404110
<NET-INVESTMENT-INCOME> 27293338
<REALIZED-GAINS-CURRENT> 89217459
<APPREC-INCREASE-CURRENT> 303441041
<NET-CHANGE-FROM-OPS> 419951838
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> 5282880
<DISTRIBUTIONS-OF-GAINS> 3162384
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 16505963
<NUMBER-OF-SHARES-REDEEMED> 1892126
<SHARES-REINVESTED> 302757
<NET-CHANGE-IN-ASSETS> 1127323067
<ACCUMULATED-NII-PRIOR> 145174
<ACCUMULATED-GAINS-PRIOR> (2618874)
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 8151990
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 23404110
<AVERAGE-NET-ASSETS> 865387000
<PER-SHARE-NAV-BEGIN> 24.00
<PER-SHARE-NII> .10
<PER-SHARE-GAIN-APPREC> 2.91
<PER-SHARE-DIVIDEND> .14
<PER-SHARE-DISTRIBUTIONS> .08
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 26.79
<EXPENSE-RATIO> 1.78
<AVG-DEBT-OUTSTANDING> 0
<AVG-DEBT-PER-SHARE> 0
</TABLE>
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000823483
<NAME> OPPENHEIMER MAIN STREET INCOME & GROWTH - CLASS C
<SERIES>
<NUMBER> 2
<NAME> OPPENHEIMER MAIN STREET FUNDS, INC.
<S> <C>
<PERIOD-TYPE> 6-MOS
<FISCAL-YEAR-END> JUN-30-1996
<PERIOD-START> JUL-01-1995
<PERIOD-END> DEC-31-1995
<INVESTMENTS-AT-COST> 3521984011
<INVESTMENTS-AT-VALUE> 4126771550
<RECEIVABLES> 30481865
<ASSETS-OTHER> 72723
<OTHER-ITEMS-ASSETS> 91637
<TOTAL-ASSETS> 4157417775
<PAYABLE-FOR-SECURITIES> 4800567
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 11266754
<TOTAL-LIABILITIES> 16067321
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 3462320588
<SHARES-COMMON-STOCK> 21368030
<SHARES-COMMON-PRIOR> 19259635
<ACCUMULATED-NII-CURRENT> 555009
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> 74666817
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 603808040
<NET-ASSETS> 571830552
<DIVIDEND-INCOME> 27842101
<INTEREST-INCOME> 22855347
<OTHER-INCOME> 0
<EXPENSES-NET> 23404110
<NET-INVESTMENT-INCOME> 27293338
<REALIZED-GAINS-CURRENT> 89217459
<APPREC-INCREASE-CURRENT> 303441041
<NET-CHANGE-FROM-OPS> 419951838
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> 2768778
<DISTRIBUTIONS-OF-GAINS> 1654241
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 4167339
<NUMBER-OF-SHARES-REDEEMED> 2214856
<SHARES-REINVESTED> 155912
<NET-CHANGE-IN-ASSETS> 1127323067
<ACCUMULATED-NII-PRIOR> 1145174
<ACCUMULATED-GAINS-PRIOR> (2618874)
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 8515990
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 23404110
<AVERAGE-NET-ASSETS> 517993000
<PER-SHARE-NAV-BEGIN> 23.97
<PER-SHARE-NII> .12
<PER-SHARE-GAIN-APPREC> 2.88
<PER-SHARE-DIVIDEND> .13
<PER-SHARE-DISTRIBUTIONS> .08
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 26.76
<EXPENSE-RATIO> 1.75
<AVG-DEBT-OUTSTANDING> 0
<AVG-DEBT-PER-SHARE> 0
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 823483
<NAME> Opp. Main Street California Tax-Exempt Fund-A
<SERIES>
<NUMBER> 5
<NAME> Oppenheimer Main Street Funds, Inc.
<S> <C>
<PERIOD-TYPE> 6-MOS
<FISCAL-YEAR-END> JUN-30-1996
<PERIOD-START> JUL-01-1995
<PERIOD-END> DEC-31-1995
<INVESTMENTS-AT-COST> 79,603,799
<INVESTMENTS-AT-VALUE> 82,612,475
<RECEIVABLES> 1,763,771
<ASSETS-OTHER> 8,392
<OTHER-ITEMS-ASSETS> 661,545
<TOTAL-ASSETS> 85,046,183
<PAYABLE-FOR-SECURITIES> 562,588
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 388,611
<TOTAL-LIABILITIES> 951,199
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 81,424,744
<SHARES-COMMON-STOCK> 6,407,153
<SHARES-COMMON-PRIOR> 6,461,742
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 100,511
<ACCUMULATED-NET-GAINS> (237,925)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 3,008,676
<NET-ASSETS> 80,577,959
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 2,697,251
<OTHER-INCOME> 0
<EXPENSES-NET> 255,385
<NET-INVESTMENT-INCOME> 2,441,866
<REALIZED-GAINS-CURRENT> (184,171)
<APPREC-INCREASE-CURRENT> 3,500,319
<NET-CHANGE-FROM-OPS> 5,758,014
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> 2,367,222
<DISTRIBUTIONS-OF-GAINS> 71,159
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 155,818
<NUMBER-OF-SHARES-REDEEMED> 334,386
<SHARES-REINVESTED> 123,979
<NET-CHANGE-IN-ASSETS> 3,312,279
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 20,446
<OVERDISTRIB-NII-PRIOR> 98,805
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 165,541
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 255,385
<AVERAGE-NET-ASSETS> 79,017,000
<PER-SHARE-NAV-BEGIN> 12.09
<PER-SHARE-NII> 0.37
<PER-SHARE-GAIN-APPREC> 0.50
<PER-SHARE-DIVIDEND> 0.37
<PER-SHARE-DISTRIBUTIONS> 0.01
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 12.58
<EXPENSE-RATIO> 0.58
<AVG-DEBT-OUTSTANDING> 0
<AVG-DEBT-PER-SHARE> 0.00
</TABLE>
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 823483
<NAME> Opp. Main Street California Tax-Exempt Fund-B
<SERIES>
<NUMBER> 5
<NAME> Oppenheimer Main Street Funds, Inc.
<S> <C>
<PERIOD-TYPE> 6-MOS
<FISCAL-YEAR-END> JUN-30-1996
<PERIOD-START> JUL-01-1995
<PERIOD-END> DEC-31-1995
<INVESTMENTS-AT-COST> 79,603,799
<INVESTMENTS-AT-VALUE> 82,612,475
<RECEIVABLES> 1,763,771
<ASSETS-OTHER> 8,392
<OTHER-ITEMS-ASSETS> 661,545
<TOTAL-ASSETS> 85,046,183
<PAYABLE-FOR-SECURITIES> 562,588
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 388,611
<TOTAL-LIABILITIES> 951,199
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 81,424,744
<SHARES-COMMON-STOCK> 279,958
<SHARES-COMMON-PRIOR> 219,253
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 100,511
<ACCUMULATED-NET-GAINS> (237,925)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 3,008,676
<NET-ASSETS> 3,517,025
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 2,697,251
<OTHER-INCOME> 0
<EXPENSES-NET> 255,385
<NET-INVESTMENT-INCOME> 2,441,866
<REALIZED-GAINS-CURRENT> (184,171)
<APPREC-INCREASE-CURRENT> 3,500,319
<NET-CHANGE-FROM-OPS> 5,758,014
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> 76,350
<DISTRIBUTIONS-OF-GAINS> 3,041
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 62,412
<NUMBER-OF-SHARES-REDEEMED> 5,560
<SHARES-REINVESTED> 3,853
<NET-CHANGE-IN-ASSETS> 3,312,279
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 20,446
<OVERDISTRIB-NII-PRIOR> 98,805
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 165,541
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 255,385
<AVERAGE-NET-ASSETS> 3,091,000
<PER-SHARE-NAV-BEGIN> 12.08
<PER-SHARE-NII> 0.31
<PER-SHARE-GAIN-APPREC> 0.49
<PER-SHARE-DIVIDEND> 0.31
<PER-SHARE-DISTRIBUTIONS> 0.01
<RETURNS-OF-CAPITAL> 0.00
<PER-SHARE-NAV-END> 12.56
<EXPENSE-RATIO> 1.59
<AVG-DEBT-OUTSTANDING> 0
<AVG-DEBT-PER-SHARE> 0.00
</TABLE>
