OPPENHEIMER GLOBAL BIO TECH FUND
497, 1994-02-10
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                                OPPENHEIMER GLOBAL BIO-TECH FUND
                                Supplement dated February 3, 1994
                            to the Prospectus dated February 1, 1994

       The Prospectus is amended as follows:

       The following text is inserted after the first sentence in the second
paragraph in the section of the Prospectus entitled "How To Buy Shares --
Minimum Investment":

       The $25,000 monthly limit on purchases described in the previous
       sentence does not apply to purchases of shares in the amount of
       $1 million or more by an "institutional investor." The
       determination as to whether a particular investor is an
       "institutional investor" shall be made by the Distributor, in
       its sole discretion, based upon information provided to it at
       the time of purchase by the investor or the investor's dealer
       and which is satisfactory to the Distributor.


February 3, 1994                                                    PS750




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