OPPENHEIMER GLOBAL BIO TECH FUND
PRE 14A, 1994-07-20
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<PAGE>
                                                       Preliminary Copy


                    OPPENHEIMER GLOBAL BIO-TECH FUND

      PROXY FOR SHAREHOLDERS MEETING TO BE HELD SEPTEMBER 19, 1994

     The undersigned shareholder of Oppenheimer Global Bio-Tech Fund (the
"Fund"), does hereby appoint George C. Bowen, Andrew J. Donohue, Robert
Bishop and Scott Farrar, and each of them, as attorneys-in-fact and
proxies of the undersigned, with full power of substitution, to attend the
Meeting of Shareholders of the Fund to be held September 19, 1994, at 3410
South Galena Street, Denver, Colorado 80231 at 10:00 a.m., Denver time,
and at all adjournments thereof, and to vote the shares held in the name
of the undersigned on the record date for said meeting for the election
of Trustees and on the proposals specified on the reverse side.  Said
attorneys-in-fact shall vote in accordance with their best judgment as to
any other matter.

PROXY SOLICITED ON BEHALF OF THE BOARD OF TRUSTEES, WHICH RECOMMENDS A
VOTE FOR THE ELECTION OF ALL NOMINEES FOR TRUSTEE AND FOR EACH PROPOSAL
ON THE REVERSE SIDE.  THE SHARES REPRESENTED HEREBY WILL BE VOTED AS
INDICATED ON THE REVERSE SIDE OR FOR IF NO CHOICE IS INDICATED.

Please mark your proxy, date and sign it on the reverse side and return
it promptly in the accompanying envelope, which requires no postage if
mailed in the United States.
                                                                  (over)

1.   Election of Trustees

     ____ FOR all nominees listed       ____ WITHHOLD AUTHORITY
          (except as marked to the           to vote for all nominees
listed
          contrary below)                    below

 L. LevyL. CherneE. DelaneyR. GalliB. LipsteinE. MoynihanK. Randall
   (A)     (B)       (C)      (D)      (E)        (F)       (G)

 E. Regan R. Reynolds S. Robbins D. Spiro P. Trigere C. Yeutter
    (H)       (I)         (J)       (K)       (L)        (M)

     INSTRUCTION:  To withhold authority to vote for any individual
     nominee, line out that nominee's name above.

2.   Ratification of selection of KPMG Peat Marwick as independent
auditors (Proposal 
     No. 1)

          FOR ____       AGAINST ____        ABSTAIN ____

3.   Approval of a change in the Fund's investment policies to permit the
Fund to emphasize investments in emerging growth companies worldwide
(Proposal No. 2) 

          FOR ____       AGAINST ____        ABSTAIN ____


                                   Dated:    _______________________, 1994
                                          (Month)             (Day)

                                        ____________________________
                                               Signature(s)

                                        ____________________________
                                               Signature(s)

                                        Please read both sides of this
ballot.


NOTE:  PLEASE SIGN EXACTLY AS YOUR NAME(S) APPEAR HEREON.  When signing
as custodian, attorney, executor, administrator, trustee, etc., please
give your full title as such.  All joint owners should sign this proxy. 
If the account is registered in the name of a corporation, partnership or
other entity, a duly authorized individual must sign on its behalf and
give title.

                                                                        

                                                          750

<PAGE>

                                               Preliminary Copy


                    OPPENHEIMER GLOBAL BIO-TECH FUND

          Two World Trade Center, New York, New York 10048-0203

              NOTICE OF MEETING OF SHAREHOLDERS TO BE HELD

                           September 19, 1994


To The Shareholders of
Oppenheimer Global Bio-Tech Fund

Notice is hereby given that a Meeting of the Shareholders of Oppenheimer
Global Bio-Tech Fund (the "Fund") will be held at 3410 South Galena
Street, Denver, Colorado, 80231, at 10:00 A.M., Denver time, on September
19, 1994, or any adjournments thereof, for the following purposes:

(a)  To elect thirteen Trustees to hold office until the next meeting of
shareholders called for the purpose of electing Trustees and until their
successors are elected and shall qualify;    

(b)  To ratify the selection of KPMG Peat Marwick as the independent
certified public accountants and auditors of the Fund for the fiscal year
beginning October 1, 1993 (Proposal No. 1);  

(c) To approve a change in the Fund's investment policy to permit the Fund
to emphasize investments in emerging growth companies worldwide (Proposal
No. 2); and 

(d)  To transact such other business as may properly come before the
meeting, or any adjournments thereof.

Shareholders of record at the close of business on July 15, 1994, are
entitled to vote at the meeting.  The election of Trustees and the
Proposals are more fully discussed in the Proxy Statement.  Please read
it carefully before telling us, through your proxy or in person, how you
wish your shares to be voted.  The Board of Trustees of the Fund
recommends a vote to elect each of the nominees as Trustee and in favor
of each Proposal.  WE URGE YOU TO SIGN, DATE AND MAIL THE ENCLOSED PROXY
PROMPTLY.

By Order of the Board of Trustees,

Andrew J. Donohue, Secretary

August 8, 1994

- --------------------------------------------------------------------------
Shareholders who do not expect to attend the meeting are asked to indicate
voting instructions on the enclosed proxy and to date, sign and return it
in the accompanying postage-paid envelope.  To avoid unnecessary duplicate
mailings, we ask your cooperation in promptly mailing your proxy no matter
how large or small your holdings may be.

<PAGE>
                    OPPENHEIMER GLOBAL BIO-TECH FUND
          Two World Trade Center, New York, New York 10048-0203

                             PROXY STATEMENT
     
                         MEETING OF SHAREHOLDERS
                      TO BE HELD SEPTEMBER 19, 1994


This statement is furnished to the shareholders of Oppenheimer Global
Bio-Tech Fund (the "Fund") in connection with the solicitation by the
Fund's Board of Trustees of proxies to be used at a meeting (the
"Meeting") of shareholders to be held at 3410 South Galena Street, Denver,
Colorado, 80231, at 10:00 A.M., Denver time, on September 19, 1994, or any
adjournments thereof.  It is expected that the mailing of this Proxy
Statement will be made on or about August 5, 1994.  Financial statements
covering the operations of the Fund for the fiscal year ended September
30, 1993 were mailed to all persons who were shareholders of record on
that date, and simultaneously with the mailing of this Proxy Statement
will be mailed to persons who became shareholders between September 30,
1993 (the record date for the mailing of that Annual Report) and the
record date for this shareholder meeting.

The enclosed proxy, if properly executed and returned, will be voted (or
counted as an abstention) in accordance with the choices specified
thereon, and will be included in determining whether there is a quorum to
conduct the meeting.  The proxy will be voted in favor of the nominees for
Trustee named in this Proxy Statement unless a choice is indicated to
withhold authority to vote for all listed nominees or any individual
nominee.  The proxy will be voted in favor of each Proposal unless a
choice is indicated to vote against or to abstain from voting on that
Proposal.  Shares owned of record by broker-dealers for the benefit of
their customers ("street account shares") will be voted by the broker-
dealer based on instructions received from its customers.  If no
instructions are received, the broker-dealer may (if permitted under
applicable stock exchange rules) vote such shares as record holder for the
election of Trustees and on the Proposals in the same proportion as that
broker-dealer votes street account shares for which instructions were
timely received.  If a shareholder executes and returns a proxy but fails
to indicate how the votes should be cast, the proxy will be voted in favor
of the election of each of the nominees named herein for Trustee and in
favor of each Proposal.

The proxy may be revoked at any time prior to the voting by: (1) writing
to the Secretary of the Fund at Two World Trade Center, New York, New
York, 10048-0203; (2) attending the meeting and voting in person; or (3)
signing and returning a new proxy (if returned and received in time to be
voted). 

The cost of printing and distributing these proxy materials is an  expense
of the Fund.  In addition to the solicitation of proxies by mail, proxies
may be solicited by officers or employees of the Fund's investment
adviser, Oppenheimer Management Corporation (the "Manager"), personally
or by telephone or telegraph; any expenses so incurred will also be borne
by the Fund.  Brokers, banks and other fiduciaries may be required to
forward soliciting material to their principals and to obtain
authorization for the execution of proxies.  For those services, they will
be reimbursed by the Fund for their out-of-pocket expenses.

Shares Outstanding and Entitled to Vote.  As of July 15, 1994, the record
date, there were 8,738,700.983 shares of the Fund outstanding.  Each share
of the Fund is entitled to one vote (and a fractional share is entitled
to a fractional vote) on the record date.  As of the record date, no
person owned of record or was known by the management of the Fund to be
the beneficial owner of 5% or more of the outstanding shares of the Fund,
other than the following shareholders who held 5% or more of the Fund's
outstanding shares on the record date: Merrill Lynch Pierce Fenner &
Smith, 4800 Deer Lake Drive East, Jacksonville, Florida 32246 (669,342.328
shares constituting 7.66% ownership).

                          ELECTION OF TRUSTEES

At the Meeting, thirteen Trustees are to be elected to hold office until
the next meeting of shareholders called for the purpose of electing
Trustees and until their successors shall be duly elected and shall have
qualified.  The persons named as attorneys-in-fact in the enclosed proxy
have advised the Fund that unless a proxy instructs them to withhold
authority to vote for all listed nominees or any individual nominee, all
validly executed proxies will be voted by them for the election of the
nominees named below as Trustees of the Fund.  As a Massachusetts business
trust, the Fund does not contemplate holding annual shareholder meetings
for the purpose of electing Trustees.  Thus, the Trustees will be elected
for indefinite terms until a shareholders meeting is called for the
purpose of voting for Trustees and until their successors are elected and
shall qualify.

Each of the nominees is presently a Trustee and has agreed to be nominated
and, if elected, to continue to serve as a Trustee of the Fund.  All
Trustees except Messrs. Robert G. Galli, Edward V. Regan and Clayton K.
Yeutter have been elected by shareholders of the Fund.  Each of the
Trustees is also a Trustee or Director of Oppenheimer Fund, Oppenheimer
Discovery Fund, Oppenheimer Target Fund, Oppenheimer Global Fund,
Oppenheimer Global Growth & Income Fund, Oppenheimer Special Fund,
Oppenheimer Time Fund, Oppenheimer Tax-Free Bond Fund, Oppenheimer Global
Environment Fund, Oppenheimer Gold & Special Minerals Fund, Oppenheimer
New York Tax-Exempt Fund, Oppenheimer California Tax-Exempt Fund,
Oppenheimer Multi-State Tax-Exempt Trust, Oppenheimer Asset Allocation
Fund, Oppenheimer Mortgage Income Fund, Oppenheimer Money Market Fund,
Inc., Oppenheimer U.S. Government Trust, Oppenheimer Multi-Government
Trust and Oppenheimer Multi-Sector Income Trust (together with the Fund,
the "New York OppenheimerFunds").  Mr. Spiro is President of the Fund and
each of the other New York OppenheimerFunds.

Each nominee indicated below by an asterisk is an "interested person" (as
that term is defined in the Investment Company Act of 1940, hereinafter
referred to as the "Investment Company Act") of the Fund due to the
positions indicated with the Manager or its affiliates.  The year given
below indicates when the nominee first became a Trustee or Director of any
of the New York OppenheimerFunds without a break in service.  The
beneficial ownership of shares listed below includes voting and investment
control, unless otherwise indicated below.  If any of the nominees should
be unable to accept nomination or election, it is the intention of the
persons named as attorneys-in-fact in the enclosed proxy to vote such
proxy for the election of such other person or persons selected and
nominated by disinterested Trustees as the Board of Trustees may, in its
discretion, recommend.  As of July 15, 1994 the Trustees and officers of
the Fund as a group owned 24,049.345  shares of the Fund in the aggregate,
[which is less than 1% of the outstanding shares]. 

<TABLE>
<CAPTION>
                                                                Shares
Name And                                                        Beneficially Owned
Other Information     Business Experience During the Past Five Yearsas of July 15, 1994
<S>                   <S>                                       <S>
Leon Levy             General Partner of Odyssey Partners, L.P. (investmentNone
first became a        partnership); Chairman of Avatar Holdings, Inc. (real estate
Trustee in 1959       development).
Age:  68

Leo Cherne            Chairman Emeritus of the International RescueNone
first became a        Committee (philanthropic organization); formerly Executive
Trustee in 1982       Director of the Research Institute of America.
Age:  81

Edmund T. Delaney     Attorney-at-law; formerly a member of the Connecticut484.371
first became a        State Historical Commission and Counsel to Copp, 
Trustee in 1959       Berall & Hempstead (a law firm).
Age:  80

Robert G. Galli*      Vice Chairman of the Manager; Vice President and General670.306
first became a        Counsel of Oppenheimer Acquisition Corp. ("OAC"), the Manager's
Trustee in 1993       Manager's parent holding company; formerly he held the 
Age:  60              following positions: a director of the Manager and 
                      Oppenheimer Funds Distributor, Inc. (the "Distributor"), Vice 
                      President and a director of HarbourView Asset Management 
                      Corporation ("HarbourView") and Centennial Asset Management 
                      Corporation ("Centennial"), investment adviser subsidiaries of 
                      the Manager, a director of Shareholder Financial Services, Inc. 
                      ("SFSI") and Shareholder Services, Inc. ("SSI"), transfer agent 
                      subsidiaries of the Manager, an officer of other OppenheimerFunds 
                      and Executive Vice President and General Counsel of the Manager 
                      and the Distributor.

Benjamin Lipstein     Professor Emeritus of Marketing, Stern Graduate School ofNone
first became a        Business Administration, New York University.
Trustee in 1974
Age:  71

Elizabeth B. Moynihan Author and architectural historian; a trustee of theNone
first became a        American Schools of Oriental Research; the Freer Gallery
Trustee in 1992       of Art (Smithsonian Institution), the Institute of Fine 
Age:  64              Arts (New York University) and Preservation League of New 
                      York State; a member of the Indo-U.S. Sub-Commission on 
                      Education and Culture.

Kenneth A. Randall    A director of Northeast Bancorp, Inc. (bank holding49.184
first became a        company), Dominion Resources, Inc. (electric utility 
Trustee in 1980       holding company), and Kemper Corporation (insurance 
Age:  67              and financial services company); formerly Chairman of the 
                      Board of ICL Inc. (information systems).

Edward V. Regan       President of Jerome Levy Economics Institute, Bard College; aNone
first became a        member of the U.S. Competitiveness Policy Council; a director
Trustee in 1993       of GranCare, Inc. (health care provider); formerly 
Age:  64              New York State Comptroller and a trustee, New York State 
                      and Local Retirement Fund.

Russell S. Reynolds, Jr.Founder and Chairman of Russell Reynolds Associates, Inc.246.036
first became a        (executive  recruiting); a trustee of Mystic Seaport 
Trustee in 1989       Museum, International House, Greenwich Historical 
Age:  62              Society and Greenwich Hospital.

Sidney M. Robbins     Chase Manhattan Professor Emeritus of Financial968.255
first became a        Institutions, Graduate School of Business, Columbia 
Trustee in 1963       University; Visiting Professor of Finance, University 
Age:  82              of Hawaii; a director of The Korea Fund, Inc. and The 
                      Malaysia Fund, Inc. (closed-end investment companies); 
                      member of the Board of Advisors of Olympus Private 
                      Placement Fund, L.P.; Professor Emeritus of Finance, 
                      Adelphi University.

Donald W. Spiro*      Chairman Emeritus and a director of the Manager;19,671.934
first became a        formerly Chairman of the Manager and the Distributor.
Trustee in 1985
Age:  68

Pauline Trigere       Chairman and Chief Executive Officer of Trigere,None
first became a        Inc. (design and sale of women's fashions).
Trustee in 1977
Age:  81

Clayton K. Yeutter    Counsel to Hogan & Hartson (a law firm); a directorNone
first became a        of B.A.T. Industries, Ltd. (tobacco and financial 
Trustee in 1993       services), Caterpillar, Inc. (machinery), ConAgra, 
Age:  63              Inc. (food and agricultural products), FMC Corp. 
                      (chemicals and machinery), Lindsay Manufacturing Co. and 
                      Texas Instruments, Inc. (electronics); formerly (in 
                      descending chronological order) Deputy Chairman, Bush/Quayle 
                      Presidential Campaign, Counsellor to the President (Bush) 
                      for Domestic Policy, Chairman of the Republican National 
                      Committee, Secretary of the U.S. Department of Agriculture, 
                      and U.S. Trade Representative, Executive Office of the President.
<FN>
- ------------------------
*  A nominee who is an "interested person" of the Fund under the Investment Company Act.
</TABLE>

Vote Required.  The affirmative vote of a majority of the votes cast by
shareholders of the Fund is required for the election of a nominee as
Trustee.  The Board of Trustees recommends a vote for the election of each
nominee.  

Functions of the Board of Trustees.  The primary responsibility for the
management of the Fund rests with the Board of Trustees. The Trustees meet
regularly to review the activities of the Fund and of the Manager, which
is responsible for its day-to-day operations.  Six regular meetings of the
Trustees were held in the fiscal year ended September 30, 1993. Each of
the Trustees other than Mr. Cherne was present for at least 75% of the
meetings held.  The Trustees of the Fund have appointed an Audit
Committee, comprised of Messrs. Randall (Chairman), Robbins (Vice
Chairman) and Cherne, none of whom is an "interested person" (as that term
is defined in the Investment Company Act) of the Manager or the Fund.  The
functions of the Committee include (i) making recommendations to the Board
concerning the selection of independent auditors for the Fund (subject to
shareholder ratification); (ii) reviewing the methods, scope and results
of audits and the fees charged; (iii) reviewing the adequacy of the Fund's
internal accounting procedures and controls; and (iv) establishing a
separate line of communication between the Fund's independent auditors and
its independent Trustees.  The Committee met four times during the fiscal
year ended September 30, 1993, and all members other than Mr. Cherne
attended at least 75% of the meetings held during that period.  The Board
of Trustees does not have a standing nominating or compensation committee.

Remuneration of Trustees and Officers.  The officers of the Fund listed
below are affiliated with the Manager.  They and the Trustees who are
affiliated with the Manager (Messrs. Spiro and Galli) receive no salary
or fee from the Fund.  The Fund currently pays each other Trustee a fee
varying from $1,824 to $4,935 for serving as Trustee, or as Chairman or
a member of the committees of the Board of Trustees.  During the fiscal
year ended September 30, 1993, Trustees' fees and expenses aggregated
$80,788.  In addition, the Fund has adopted a retirement plan that
provides for payment to a retired independent Trustee of up to 80% of the
average compensation paid during that Trustee's five years of service in
which the highest compensation was received.  A Trustee must serve in that
capacity for any of the New York OppenheimerFunds listed above for at
least 15 years in order to be eligible for the maximum payment.  No
Trustee has retired under this plan, and therefore no payments have been
made by the Fund.  At September 30, 1993, the Fund had accrued $63,821 for
retirement plan benefits for its Trustees under the plan.

Officers of the Fund.  Each officer of the Fund is elected by the Trustees
to serve an indefinite term.  Information is given below about the
executive officers who are not Trustees of the Fund, including their
business experience during the past five years.  Messrs. Bishop, Bowen,
Donohue, Farrar and Zack serve in a similar capacity with the other New
York OppenheimerFunds listed above.

James Ayer, Vice President and Portfolio Manager; Age: 30.
     Assistant Vice President of the Manager; an officer of other
     OppenheimerFunds; formerly an international equities investment
     officer with Brown Brothers Harriman & Company.

Andrew J. Donohue, Secretary; Age: 43.
     Executive Vice President and General Counsel of the Manager and the
     Distributor; an officer of other OppenheimerFunds; formerly Senior
     Vice President and General Counsel of the Manager and the
     Distributor, Partner in Kraft & McManimon (a law firm), an officer
     of First Investors Corporation (a broker-dealer) and First Investors
     Management Company, Inc. (broker-dealer and investment adviser) and
     director and an officer of First Investors Family of Funds and First
     Investors Life Insurance Company. 

George C. Bowen, Treasurer; Age 57.
     Senior Vice President and Treasurer of the Manager; Vice President
     and Treasurer of the Distributor and HarbourView; Senior Vice
     President, Treasurer, Assistant Secretary and a director of
     Centennial; Vice President, Treasurer and Secretary of SSI and SFSI;
     an officer of other OppenheimerFunds; formerly Senior Vice
     President/Comptroller and Secretary of Oppenheimer Asset Management
     Corporation, a former investment advisory subsidiary of the Manager.

Robert G. Zack, Assistant Secretary; Age 45.
     Senior Vice President and Associate General Counsel of the Manager;
     Assistant Secretary of SSI, SFSI and other OppenheimerFunds.

Robert Bishop, Assistant Treasurer; Age 35.
     Assistant Vice President of the Manager/Mutual Fund Accounting; an
     officer of other OppenheimerFunds; previously a Fund Controller for
     the Manager, prior to which he was an Accountant for Yale &
     Seffinger, an accounting firm, and previously an Accountant and
     Commissions Supervisor for Stuart James Company Inc., a broker-
     dealer.

Scott Farrar, Assistant Treasurer; Age:  28.
     Assistant Vice President of the Manager/Mutual Fund Accounting; an
     officer of other OppenheimerFunds; previously a Fund Controller for
     the Manager, prior to which he was an International Mutual Fund
     Supervisor for Brown Brothers Harriman Co., a bank, and previously
     a Senior Fund Accountant for State Street Bank & Trust Company,
     before which he was a sales representative for Central Colorado
     Planning.

            RATIFICATION OF SELECTION OF INDEPENDENT AUDITORS
                            (Proposal No. 1)

The Investment Company Act requires that independent certified public
accountants and auditors ("auditors") be selected annually by the Board
of Trustees and that such selection be ratified by the shareholders at the
next-convened annual meeting of the Fund, if one is held.  The Board of
Trustees of the Fund, including a majority of the Trustees who are not
"interested persons" (as defined in the Investment Company Act) of the
Fund or the Manager, at a meeting held October 6, 1993, selected KPMG Peat
Marwick ("KPMG") as auditors of the Fund for the fiscal year beginning
October 1, 1993.  KPMG also serves as auditors for certain other funds for
which the Manager acts as investment adviser.  At the Meeting, a
resolution will be presented for the shareholders' vote to ratify the
selection of KPMG as auditors.  Representatives of KPMG are not expected
to be present at the Meeting but will be available should any matter arise
requiring their presence.  The Board of Trustees recommends approval of
the selection of KPMG as auditors of the Fund.

                      APPROVAL OF AMENDMENT TO THE
                 FUND'S FUNDAMENTAL INVESTMENT POLICIES
                            (Proposal No. 2)

The Fund currently has a fundamental investment policy that the Fund
shall, under normal market conditions, invest at least 65% of its total
assets in securities of biotechnology companies located in the United
States and in at least three foreign countries.  

At a meeting of the Fund's Board of Trustees on June 16, 1994, the Board,
including a majority of the Trustees who are not "interested persons" (as
defined in the Investment Company Act) of the Fund or the Manager (the
"Independent Trustees"), approved a change in its fundamental investment
policies.  Subject to shareholder approval, the current policy requiring
generally at least 65% of total assets in securities of biotechnology
companies located in the U.S. and at least three foreign countries would
be eliminated, and the Fund's investment policies would be broadened to
emphasize investments in emerging growth companies worldwide.  As a
result, the Fund would become a global emerging growth fund.  If
shareholders approve this Proposal, the Board expects to change the Fund's
name to Oppenheimer Global Emerging Growth Fund or such other name as it
deems appropriate.  The Fund's fundamental investment objective of capital
appreciation would remain unchanged.  Oppenheimer Management Corporation
(the "Manager") will continue as the Fund's investment adviser. 

As a global emerging growth fund, under normal market conditions the Fund
would invest at least 65% of its total assets in securities of emerging
growth companies located in the United States and at least three foreign
countries.  This new investment policy will be a non-fundamental policy
that may be changed by the Board of Trustees in response to changing
market conditions without further shareholder approval.  

As a global emerging growth fund, the Fund would pursue growth
opportunities from companies in their early stages of development, as it
looks for the most promising areas, both in the U.S. and abroad, for
accelerated growth of earnings or revenues.  Emerging growth companies are
often smaller companies in terms of sales assets or capitalization. 
Emerging growth companies can be any size and can be in any industry. 
Small capitalization stocks, historically, have outperformed large
capitalization stocks according to data complied from Ibbotson Associates. 
Small companies tend to respond more quickly (and tend to exhibit greater
volatility in price and performance) than larger companies to market
changes and consequently their expansion can occur faster. 

The Manager would use a global "theme oriented approach" in managing the
Fund as a global emerging growth fund.  This is the same approach the
Manager uses in managing other global funds that it advises.  This "theme
oriented approach" seeks to capitalize on important global trends that the
Manager believes offers the most promising areas for long-term growth. 
Examples of current themes include telecommunications, developing markets,
emerging consumer markets and the environment, together with
biotechnology.  The Manager further believes that non-U.S. stocks will
continue to outperform U.S. stocks due to rebounding economies overseas
and earnings growth rates that the Manager anticipates will be
significantly higher than those of domestic markets.  If this Proposal is
approved, the Fund would reserve the freedom to concentrate its
investments (that is, invest 25% or more of its total assets) in
securities of biotechnology companies for an interim transition period to
permit an orderly reduction in its bio-tech position.  Otherwise, the
Manager does not intend to concentrate its investments in any industry.

Considerations by the Board of Trustees.  In connection with this
Proposal, the Board of Trustees considered that the Fund's shareholders
would be better served by expanding the Fund's investment policies to
allow broader investments in domestic and foreign high-potential, emerging
growth companies.  This would give the Fund the flexibility to pursue
growth opportunities across various industries.  The risk of volatility
generally associated with emphasizing investments in only one sector (that
is, the biotechnology sector) should be greatly reduced, although emerging
growth companies may be more volatile than mature companies. 
Nevertheless, if this Proposal is approved, the Fund anticipates that it
may continue to invest in biotechnology companies.  The Manager believes
that a broadening of the Fund's investment policies is consistent with its
overall philosophy to provide shareholders with the most responsible
portfolio management.  After completion of its review, the Independent
Trustees recommended that the Board of Trustees approve, and the Board
unanimously approved, the Proposal.

Vote Required.  The affirmative vote of the holders of a "majority" of the
outstanding shares of the Fund is required for approval of this Proposal. 
Such "majority" vote is defined in the Investment Company Act as the vote
of the holders of the lesser of (i) 67% or more of the shares present or
represented by proxy at the shareholder meeting, if the holders of more
than 50% of the outstanding shares are present or represented by proxy,
or (ii) more than 50% of the outstanding shares.  If the Proposal is not
approved, the Fund's investment policy that generally at least 65% of its
total assets shall be invested in biotechnology companies located in the
United States and at least three foreign countries will remain unchanged. 
The Board of Trustees recommends a vote in favor of approving this
Proposal.

                         ADDITIONAL INFORMATION

The Manager.  Subject to the authority of the Board of Trustees, the
Manager is responsible for the day-to-day management of the Fund's
business.  The Manager is a wholly-owned subsidiary of Oppenheimer
Acquisition Corp. ("OAC"), a holding company controlled by Massachusetts
Mutual Life Insurance Company ("MassMutual").  MassMutual is located at
1295 State Street, Springfield, Massachusetts 01111.  OAC acquired the
Manager on October 22, 1990 (the "Acquisition Date").  As indicated below,
the common stock of OAC is owned by (i) certain officers and/or directors
of the Manager, (ii) MassMutual and (iii) another investor.  No
institution or person holds 5% or more of OAC's outstanding common stock
except Donald W. Spiro (5.24%) and MassMutual.  MassMutual has engaged in
the life insurance business since 1851.  It is the nation's twelfth
largest life insurance company by assets and has an A.M. Best Co. rating
of "A++".

The common stock of OAC is divided into three classes.  At June 30, 1994,
MassMutual held (i) all of the 2,160,000 shares of Class A voting stock,
(ii) 342,766 shares of Class B voting stock, and (iii) 380,153 shares of
Class C non-voting stock. This collectively represented 75.2% of the
outstanding common stock and 85.3% of the voting power of OAC as of
December 31, 1993.  Certain officers and/or directors of the Manager held
(i) 786,543 shares of the Class B voting stock, representing 20.5% of the
outstanding common stock and 12.2% of the voting power, and (ii) options
acquired without cash payment which, when they become exercisable, allow
the holders to purchase up to 811,554 shares of Class C non-voting stock.1 
That group includes persons who serve as officers of the Fund and two of
whom (Messrs. Donald W. Spiro and Robert G. Galli) serve as Trustees of
the Fund.  Holders of OAC Class B and Class C common stock may put (sell)
their shares and vested options to OAC or MassMutual at a formula price
(based on earnings of the Manager).  MassMutual may exercise call
(purchase) options on all outstanding shares of both such classes of
common stock and vested options at the same formula price, according to
a schedule that will commence September 30, 1995.  Since January 1, 1993,
certain officers and/or directors of the Manager (i) sold 320,266 shares
of Class B OAC common stock to MassMutual at the formula price, and (ii)
surrendered to OAC 466,916 stock appreciation rights issued in tandem with
the Class C OAC options.  Cash payments aggregating $37,777,598 have or
will be made by OAC or MassMutual to such persons (including Messrs. Spiro
and Galli, identified above) in such transactions as follows: one-third
of the amount due (i) within 30 days of the transaction, (ii) by the first
anniversary following the transaction (with interest), and (iii) by the
second anniversary following the transaction (with interest).  On December
15, 1993 and June 15, 1994, MassMutual purchased its 380,153 shares of
Class C OAC stock from OAC for a total consideration of $20,489,833.

As part of the acquisition of the common stock of OAC, MassMutual also
purchased approximately $45 million of subordinated notes of a subsidiary
of OAC; the notes are now an obligation of the Manager.  In addition to
the purchase of such notes, MassMutual holds warrants issued by OAC
exercisable over the life of the notes which will allow it to purchase
shares of Class C common stock representing approximately 13.3% of the
common stock of OAC on a fully diluted basis.  

The Manager and its affiliates act as investment advisers to investment
companies having combined net assets of more than $28 billion as of June
30, 1994, and having more than 1.8 million shareholder accounts.  A
Consolidated Statement of Financial Condition of the Manager as of
December 31, 1993, is included in this Proxy Statement as Exhibit A. 

The names and principal occupations of the executive officers and
directors of the Manager are as follows: Jon S. Fossel, Chairman, Chief
Executive Officer and Director; Bridget A. Macaskill, President and
Director; Donald W. Spiro, Chairman Emeritus and a Director; Robert G.
Galli and James C. Swain, Vice Chairmen; Samuel Freedman, Jr., Director;
Robert Doll, Jr., and O. Leonard Darling, Executive Vice Presidents;
Tilghman G. Pitts, Executive Vice President and Director; Andrew J.
Donohue, Executive Vice President and General Counsel; Kenneth Eich,
Executive Vice President and Chief Financial Officer; George C. Bowen,
Senior Vice President and Treasurer; Barbara Hennigar, President and Chief
Executive Officer of Oppenheimer Shareholder Services, a division of the
Manager; Victor Babin, Loretta McCarthy, Robert Patterson, Arthur
Steinmetz, Ralph Stellmacher, Nancy Sperte and Robert G. Zack, Senior Vice
Presidents.  The address of Messrs. Bowen, Eich, Freedman and Swain is
3410 South Galena Street, Denver, Colorado 80231.  The address of all
other officers is Two World Trade Center, New York, New York 10048-0203,
which is also the address of the Manager and OAC.

Investment Advisory Agreement.  The Fund has an Investment Advisory
Agreement with the Manager dated June 1, 1992 (the "Agreement") that was
submitted to and approved by the shareholders of the Fund at a meeting
held May 15, 1992.  The Agreement continues in effect from year to year
unless terminated, but only so long as such continuance is approved
annually in accordance with the Investment Company Act.  At a meeting held
on December 9, 1993, the Fund's Board of Trustees, including a majority
of the Independent Trustees, approved the renewal of the Agreement between
the Manager and the Fund until December 31, 1994.  At the time of such
approval, Messrs. Spiro and Galli were shareholders of OAC, the parent of
the Manager.  Under the Agreement, the Manager supervises the investment
operations of the Fund and the composition of its portfolio and furnishes
advice and recommendations with respect to investments, investment
policies and the purchase and sale of securities.  The management fee
payable monthly to the Manager under the terms of the Agreement is
computed on the net assets of the Fund as of the close of business each
day.  The annual rates of the fee paid by the Fund are: 1% of the first
$50 million of average annual net assets, .75% of the next $150 million,
.72% of the next $200 million, .69% of the next $200 million, .66% of the
next $200 million and .60% of net assets in excess of $800 million. 
During the fiscal year ended September 30, 1993, the Fund's fees payable
under its Agreement with the Manager were $864,226.

The Agreement requires the Manager, at its expense, to provide the Fund
with adequate office space, facilities and equipment, as well as to
provide, and supervise the activities of, all administrative and clerical
personnel required to provide effective administration for the Fund,
including the compilation and maintenance of records with respect to
operations, the preparation and filing of specified reports, and
composition of proxy materials and registration statements for continuous
public sale of shares of the Fund.  Expenses not expressly assumed by the
Manager under the Agreement or by the Distributor under the General
Distributor's Agreement are paid by the Fund.  The Agreement lists
examples of expenses paid by the Fund, the major categories of which
relate to interest, taxes, brokerage commissions, fees to certain
Trustees, legal, bookkeeping and audit expenses, custodian and transfer
agent expenses, stock certificate issuance costs, certain printing and
registration costs, and non-recurring expenses, including litigation
costs.

Independently of the Agreement, the Manager has voluntarily undertaken
that the total expenses of the Fund in any year (including the management
fee but excluding taxes, interest, brokerage commissions, distribution
and/or service plan payments and extraordinary non-recurring expenses such
as litigation costs) shall not exceed (and the Manager undertakes to pay
or refund to the Fund any amount by which such expenses shall exceed) the
most stringent state regulatory limitation on fund expenses applicable to
the Fund.  At present, that limitation is imposed by California and limits
expenses (with specified exclusions) to 2.5% of the first $30 million of
average annual net assets, 2% of the next $70 million, and 1.5% of average
annual net assets in excess of $100 million.  The payment of the
management fee at the end of any month will be reduced so that there will
not be any accrued but unpaid liability under this expense limitation. 
The Manager reserves the right to amend or terminate the expense
assumption undertaking at any time.

The Agreement provides that in the absence of willful misfeasance, bad
faith or gross negligence in the performance of its duties, or reckless
disregard of its obligations and duties under this Agreement, the Manager
shall not be liable for any loss sustained by reason of good faith errors
or omissions in connection with any matters to which this Agreement
relates.  The Agreement permits the Manager to act as investment adviser
for any other person, firm or corporation.  Pursuant to a license from the
Manager, the Fund may use the name "Oppenheimer" in connection with its
business.  If the Manager shall no longer act as investment adviser to the
Fund, the right of the Fund to use the name "Oppenheimer" as part of its
name may be withdrawn.

Brokerage Provisions of the Investment Advisory Agreement.  One of the
duties of the Manager under the Agreement is to arrange the portfolio
transactions for the Fund.  In doing so, the Manager is authorized by the
Agreement to employ broker-dealers ("brokers"), including "affiliated"
brokers, as that term is defined in the Investment Company Act, as may,
in its best judgment based on all relevant factors, implement the policy
of the Fund to obtain, at reasonable expense, the "best execution" (prompt
and reliable execution at the most favorable price obtainable) of such
transactions.  The Manager need not seek competitive commission bidding
or base its selection on "posted" rates, but is expected to be aware of
the current rates of eligible brokers and to minimize the commissions paid
to the extent consistent with the provisions of the Agreement and the
interests and policies of the Fund as established by its Board of
Trustees. 

Under the Agreement, the Manager is authorized to select brokers that
provide brokerage and/or research services for the Fund and/or the other
accounts over which the Manager or its affiliates have investment
discretion.  The commissions paid to such brokers may be higher than
another qualified broker would have charged, if a good faith determination
is made by the Manager that the commission is fair and reasonable in
relation to the services provided.  There is no formula under which any
of the brokers selected for the Fund's portfolio transactions are entitled
to the allocation of a particular amount of commissions.  The Manager may
also consider sales of shares of the Fund and of other investment
companies managed by the Manager or its affiliates as a factor in the
selection of brokers for the Fund's portfolio transactions. 

Description of Brokerage Practices.  Subject to the provisions of the
Agreement, when brokers are used for the Fund's portfolio transactions,
allocations of brokerage are made by portfolio managers under the
supervision of executive officers of the Manager. Transactions in
securities other than those for which an exchange is the primary market
are generally done with principals or market makers.  Brokerage
commissions are paid primarily for effecting transactions in listed
securities and otherwise only if it appears likely that a better price or
execution can be obtained.  When the Fund engages in an option
transaction, ordinarily the same broker will be used for the purchase or
sale of the option and any transactions in the securities to which the
option relates.  When possible, concurrent orders to purchase or sell the
same security by more than one of the accounts managed by the Manager or
its affiliates are combined.  Transactions effected pursuant to such
combined orders are averaged as to price and allocated in accordance with
the purchase  or sale orders actually placed for each account.  Option
commissions may be relatively higher than those which would apply to
direct purchases and sales of portfolio securities. 

Most purchases of money market instruments and debt obligations are
principal transactions at net prices.  For those transactions, instead of
using a broker the Fund normally deals directly with the selling or
purchasing principal or market maker unless it is determined that a better
price or execution can be obtained by using a broker.  Purchases of these
securities from underwriters include a commission or concession paid by
the issuer to the underwriter, and purchases from dealers include a spread
between the bid and asked price.  The Fund seeks to obtain prompt
execution of such orders at the most favorable net price.

The research services provided by a  particular broker may be useful only
to one or more of the advisory accounts of the Manager and its affiliates,
and investment research received for the commissions of those other
accounts may be useful both to the Fund and one or more of such other
accounts.  Such research, which may be supplied by a third party at the
instance of a broker, includes information and analyses on particular
companies and industries as well as market or economic trends and
portfolio strategy, receipt of market quotations for portfolio
evaluations, information systems, computer hardware and similar products
and services.  If a research service also assists the Manager in a non-
research capacity (such as bookkeeping or other administrative functions),
then only the percentage or component that provides assistance to the
Manager in the investment decision-making process may be paid for in
commission dollars.  The research services provided by brokers broaden the
scope and supplement the research activities of the Manager, by making
available additional views for consideration and comparisons, and enabling
the Manager to obtain market information for the valuation of securities
held in the Fund's portfolio or being considered for purchase.  The Board
of Trustees, including the Independent Trustees of the Fund, annually
reviews information furnished by the Manager as to the commissions paid
to brokers furnishing such services in an effort to ascertain that the
amount of such commissions was reasonably related to the value or benefit
of such services.  The Board of Trustees has permitted the Manager to use
concessions on fixed-price offerings to obtain research, in the same
manner as is permitted for agency transactions.

During the fiscal year ended September 30, 1993, total brokerage
commissions paid by the Fund (not including spreads or concessions on
principal transactions on a net trade basis) amounted to $414,002.  During
the fiscal year ended September 30, 1993, $36,731 was paid to brokers as
commissions in return for research services (including special research,
statistical information and execution); the aggregate dollar amount of
those transactions was $19,817,816.  The transactions giving rise to those
commissions were allocated in accordance with the internal allocation
procedures described above. 

General Distributor's Agreement.  Oppenheimer Funds Distributor, Inc., a
wholly-owned subsidiary of the Manager, is the general distributor of the
Fund's shares under a General Distributor's Agreement dated October 22,
1990.  The General Distributor's Agreement is subject to the same annual
renewal requirements and termination provisions as the Agreement.  For the
fiscal year ended September 30, 1993, selling charges on the Fund's shares
amounted to $4,353,366, of which the Distributor and an affiliated broker-
dealer retained $940,748 in the aggregate.  

Service Contract.  Oppenheimer Shareholder Services ("OSS"), a division
of the Manager, serves as the Fund's transfer agent and registrar pursuant
to a Service Contract under which it is reimbursed by the Fund for its
costs in providing those services to the Fund, including the cost of
rental of office space.  Similar services are provided by OSS to certain
other mutual funds advised by the Manager.  OSS received $650,147 from the
Fund during the fiscal year ended September 30, 1993.  The costs described
for these services are charged to the Fund as operating expenses to the
respective class and are borne ratably by all shareholders of that class
in proportion to their holdings of shares.

                    RECEIPT OF SHAREHOLDER PROPOSALS

The Fund is not required to hold shareholder meetings on a regular basis. 
Special meetings of shareholders may be called from time to time by either
the Fund or the shareholders (under special conditions described in the
Fund's Statement of Additional Information).  Under the Commission's proxy
rules, shareholder proposals which meet certain conditions may be included
in the Fund's proxy statement and proxy for a particular meeting.  Those
rules require that for future meetings the shareholder must be a record
or beneficial owner of Fund shares with a value of at least $1,000 at the
time the proposal is submitted and for one year prior thereto, and must
continue to own such shares through the date on which the meeting is held. 
Another requirement relates to the timely receipt by the Fund of any such
proposal.  Under those rules, a proposal submitted for inclusion in the
Fund's proxy material for the next meeting after the meeting to which this
proxy statement relates must be received by the Fund a reasonable time
before the solicitation is made.  The fact that the Fund receives a
proposal from a qualified shareholder in a timely manner does not ensure
its inclusion in the proxy material, since there are other requirements
under the proxy rules for such inclusion.

                             OTHER BUSINESS

Management of the Fund knows of no business other than the matters
specified above that will be presented at the Meeting.  Since matters not
known at the time of the solicitation may come before the Meeting, the
proxy as solicited confers discretionary authority with respect to such
matters as properly come before the Meeting, including any adjournment or
adjournments thereof, and it is the intention of the persons named as
attorneys-in-fact in the proxy to vote the proxy in accordance with their
judgment on such matters.

By Order of the Board of Trustees,

Andrew J. Donohue, Secretary

August 8, 1994



<PAGE>

                                             Exhibit A

INDEPENDENT AUDITORS' REPORT


Oppenheimer Management Corporation:

We have audited the accompanying consolidated statement of financial
condition of Oppenheimer Management Corporation and subsidiaries as of
December 31, 1993.  This financial statement is the responsibility of the
Company's management.  Our responsibility is to express an opinion on this
financial statement based on our audit.

We conducted our audit in accordance with generally accepted auditing
standards.  Those standards require that we plan and perform the audit to
obtain reasonable assurance about whether the statement of financial
condition is free of material misstatement.  An audit includes examining,
on a test basis, evidence supporting the amounts and disclosures in the
statement of financial condition.  An audit also includes assessing the
accounting principles used and significant estimates made by management,
as well as evaluating the overall statement of financial condition
presentation.  We believe that our audit provides a reasonable basis for
our opinion.

In our opinion, such consolidated statement of financial condition
presents fairly, in all material respects, the financial position of
Oppenheimer Management Corporation and subsidiaries at December 31, 1993
in conformity with generally accepted accounting principles.

As discussed in Note 1 to the financial statements, the Company changed
its method of accounting for income taxes to conform with Statement of
Financial Accounting Standards No. 109.



DELOITTE & TOUCHE




Denver, Colorado
February 16, 1994
<PAGE> 
OPPENHEIMER MANAGEMENT CORPORATION AND SUBSIDIARIES

CONSOLIDATED STATEMENT OF FINANCIAL CONDITION
DECEMBER 31, 1993

ASSETS                        NOTES

CURRENT ASSETS:
     Cash                               $ 31,940,116
     Investments in money market
       mutual funds                       26,850,605
     Investments in managed mutual funds                  4,981,458
     Investments in Zero Coupon U.S.
   Treasuries Trust, at market             3,897,237
     Accounts receivable:
       Brokers and dealers    2           49,538,320
   Managed mutual funds        2,3              11,433,524
          Affiliated companies               100,495
          Income taxes                    13,902,237
          Other                            4,471,131
     Other current assets                  2,124,857
                                          -------------

Total current assets                     149,239,980
                                        -----------------   
PROPERTY AND EQUIPMENT - Less
  accumulated depreciation and
  amortization of $8,169,031               8,896,837
                                         -----------------

OTHER ASSETS:
     Intangible assets, net   1          113,445,572
     Deferred sales commissions           54,452,051
     Deferred charges                      1,550,484
     Other                                 1,607,387
                                          ----------------

Total other assets                        171,055,494
                                         ------------------
 



TOTAL          $329,192,311

<PAGE>

LIABILITIES AND SHAREHOLDER'S EQUITY    
                                 NOTES
CURRENT LIABILITIES:
  Accounts payable and accrued
    expenses                            $ 33,866,353
  Subscriptions payable to managed 
    mutual funds                   2      71,371,285
     Payable to brokers and dealers             2         9,483,935
     Current portion of long-term debt        5,6        17,463,094
                                         ------------

Total current liabilities                132,184,667
                                        --------------

LONG-TERM LIABILITIES:
  Deferred income taxes4           4      15,447,486
     Senior debt                   5      59,781,186
     Subordinated notes            6      44,450,000
                                         -------------
Total liabilities                        251,863,339
                                         ---------------

COMMITMENTS                        1,8 

SHAREHOLDER'S EQUITY:              5,7 
     Preferred stock - nonvoting;
          $10 par value; 392,461 shares
          authorized; 25,141 shares
          issued and outstanding             251,410
     Common Stock - voting; $.10 par
          value; 229,246 shares authorized;
          179,658 shares issued and 
          outstanding                         17,966
     Additional paid-in capital           49,241,234
     Retained earnings                    27,818,362
                                        ----------------    
Total shareholder's equity                  77,328,972
                                        -----------------

TOTAL                                   $329,192,311


See notes to consolidated statement of financial condition.

<PAGE>

OPPENHEIMER MANAGEMENT CORPORATION AND SUBSIDIARIES

NOTES TO CONSOLIDATED STATEMENT OF FINANCIAL CONDITION
DECEMBER 31, 1993

1.   THE COMPANY AND ITS SIGNIFICANT ACCOUNTING POLICIES

     Oppenheimer Management Corporation (OMC) and its subsidiaries
     (collectively, the "Company") are engaged in the business of
     organizing, promoting, and managing registered investment companies
     (hereafter referred to as "mutual funds").

     OMC owns all the outstanding stock of Oppenheimer Funds Distributor,
     Inc., Shareholder Services, Inc. (SSI), HarbourView Asset Management
     Corporation, Centennial Asset Management Corporation, Oppenheimer
     Partnership Holdings, Inc., and Shareholder Financial Services, Inc. 
     OMC is a wholly-owned subsidiary of Oppenheimer Acquisition
     Corporation (OAC), which is controlled by Massachusetts Mutual Life
     Insurance Company and senior management of OMC.    

     Principles of Consolidation - The accompanying consolidated statement
     of financial condition includes the accounts of OMC and its
     subsidiaries.  All significant intercompany transactions and balances
     have been eliminated in consolidation.

     Investments in Money Market Mutual Funds - The Company invests
     available cash in money market mutual funds managed by the Company. 
     The investments are recorded at cost which equals market.

     Investments in Managed Mutual Funds - The Company owns shares of
     stock in several of the mutual funds it manages.  The shares are
     purchased at their respective net asset values.  The resulting
     investments are recorded at cost which approximates market.

     Investments in Zero Coupon U.S. Treasuries Trust - The Company is the
     Sponsor for the Oppenheimer Zero Coupon U.S. Treasuries Trust and has
     undertaken to maintain a secondary market for units in the Trust. 
     The investments are carried at market.

     Property and Equipment - Property and equipment is recorded at cost. 
     Equipment depreciation expense is provided over the assets' estimated
     useful lives on the straight-line method.  Leasehold improvements are
     amortized on the straight-line method over the remaining terms of the
     lease agreements.



<PAGE>
<TABLE>
<CAPTION>
   Intangible Assets - Intangible assets at December 31, 1993, are as
   follows:                                  
                                                   Less     
                            Useful              Accumulated        Net     
                            Lives     Cost      Amortization    Book Value 
                       ----------- -----------  ------------    -----------
<S>                    <C>        <C>           <C>             <C>         
Debt Issuance Costs       7 years $  5,535,450  $ (2,999,400)   $  2,536,050
Management Contracts      7 years   38,600,000   (18,840,667)     19,759,333
Goodwill                 25 years  100,766,565   (11,671,455)     89,095,110
Other                  4-10 years    4,385,906    (2,330,827)      2,055,079
                                   -----------   ------------     ----------
                                  $149,287,921  $(35,842,349)   $113,445,572
</TABLE>                                      
                                              
   Deferred Sales Commissions - Sales commissions paid to brokers and
   dealers in connection with sales of shares of certain mutual funds are
   charged to deferred sales commissions and amortized over six years. 
   Early withdrawal charges received by the Company from redeeming
   shareholders reduce unamortized deferred sales commissions.  

   Stock Appreciation Rights - OAC has granted certain stock appreciation
   rights relating to OAC's stock to certain employees of OMC.  During
   1993, OMC recorded $21,603,294 relating to these stock appreciation
   rights as a credit to additional paid-in capital.

   Income Taxes - OAC files a consolidated federal income tax return which
   includes the Company.  Income taxes are recorded as if the Company
   files on a separate return basis.  During 1993 the Company was required
   to adopt Statement of Financial Accounting Standards No. 109,
   Accounting for Income Taxes.  Statement 109 requires a change from the
   deferred method of accounting for income taxes of APB Opinion 11 to the
   asset and liability method of accounting for income taxes.  The asset
   and liability method prescribed by Statement 109 results in deferred
   tax assets and liabilities being recorded for the differences between
   the book and tax basis relating to the Company's assets and
   liabilities.

   The Company adopted Statement 109 in 1993 and has elected to restate
   prior years beginning with the 1990 period.  The effect of this
   restatement on prior years has been reflected in retained earnings as
   of December 31, 1992.


2. TRANSACTIONS WITH BROKERS AND DEALERS

   The Company acts as general distributor for the sale and distribution
   of shares of several mutual funds.  In this capacity, the Company
   records a receivable when it issues confirmations of all accepted
   purchase orders to the originating brokers and dealers; at the same
   time, the Company records a liability to the mutual funds equal to the
   net asset value of all shares subject to such confirmations.  This
   liability must be paid to the mutual funds within 11 business days
   unless the trade is canceled.  If the originating broker or dealer
   fails to make timely settlement of its purchase order under the terms
   of its dealer agreement with the Company, the Company may cancel the
   purchase order and, at the Company's risk, hold responsible the
   originating broker or dealer.

   When brokers and dealers place share redemption orders with a fund's
   distributor, the Company records a receivable from the mutual funds
   equal to the net asset value of all shares redeemed; at the same time
   the Company records a corresponding liability payable to the
   originating brokers.

3. RELATED PARTIES

   The following is a summary of the significant balances, transactions
   and relationships with affiliated companies and other related parties
   as of December 31, 1993:

   Officers and Directors of the Company; Shareholders of OAC - Several
   officers and directors of the Company and shareholders of OAC are also
   officers and directors or trustees of the mutual funds managed and
   distributed by the Company.

   Transfer Agents - SSI and Oppenheimer Shareholder Services (OSS), a
   division of OMC, act as transfer and shareholder servicing agents for
   the mutual funds managed by the Company and others.  Amounts charged
   to managed mutual funds are based on costs incurred on behalf of the
   mutual funds pursuant to service agreements between SSI or OSS and the
   mutual funds.  SSI also acts as transfer agent for certain mutual funds
   not managed by the Company, and amounts charged to those funds are
   based on fees set by contracts with the respective mutual funds.

   The receivable from managed mutual funds includes $2,466,000 resulting
   from transfer agency fees and expenditures made on behalf of the mutual
   funds at December 31, 1993.

4. INCOME TAXES

   As discussed in note 1, the Company adopted Statement 109 in 1993 and
   has applied the provisions of the Statement retroactively to 1990.  The
   principal effect of this change in accounting for income taxes related
   to the remeasurement of the 1990 acquisition of Maximum Holdings, Inc.
   and resulted in the recording of goodwill in the amount of $13,800,000
   and deferred taxes payable in the same amount.  In addition, retained
   earnings at December 31, 1992 was increased by $2,001,702 to reflect
   the effects of the restatement as of that date.

   Deferred tax assets of $20,165,000 have been recorded in the
   accompanying financial statements.  These amounts primarily relate to
   the benefit associated with certain state tax loss carryforwards and
   compensation not deductible for tax purposes until paid.  A valuation
   allowance has not been recorded with respect to this deferred tax
   asset.  Deferred tax liabilities of $35,612,000 have also been
   recorded.  These amounts relate primarily to the current deduction, for
   tax purposes, of deferred sales commissions which are amortized over
   six years for book purposes and the difference in book and tax basis
   relating to certain management contracts.

   The Company has certain net operating loss carryforwards relating to
   various states.  If not used in the interim, these losses will
   generally expire on December 31, 2008.

5. SENIOR DEBT

   At December 31, 1993, the Company has outstanding $77.2 million of
   Senior Debt borrowed from five banks.  This amount is comprised of a
   term loan of $23.7 million due September 30, 1997 and $53.5 million
   outstanding on a $75 million revolving credit.  The revolving credit
   is subject to annual renewal, and, if not renewed, is repayable in four
   annual installments.  The debt bears interest at the Company's election
   at the rate for Eurodollar deposits plus 1 1/2% or the higher of the
   prime rate, plus 1/2% or the federal funds rate plus 1/2%.  The credit
   agreement contains covenants requiring certain minimum financial tests
   and restrictions on capital expenditures, investments, indebtedness and
   dividends.  At December 31, 1993, the Company was in compliance with
   the terms of the credit agreement.  In addition, the banks have also
   received a pledge of the shares of the Company's subsidiaries and
   guarantees of certain subsidiaries.  Borrowings under the credit
   agreement are collateralized by certain assets of the Company.

   The mandatory principal repayment schedule for the term loan is as
   follows (000's):
                        1994      $ 10,000
                        1995        12,000
                        1996         1,700
                                  --------
                                  $ 23,700
                                   =======

   The credit agreement has certain provisions whereby specified amounts
   of excess cash flow on a semi-annual basis, as defined in the
   agreement, must be applied to reduce the outstanding loan balance. 
   There are no prepayment penalties.

   The Company has entered into interest rate swap agreements whereby
   certain banks have agreed to pay the Company interest on a floating
   rate (Eurodollar) basis and the Company has agreed to pay the banks
   interest on a fixed rate basis.  At December 31, 1993, the Company has
   fixed an interest rate of 10.00% on $29,000,000 of the Senior Debt. 
   The interest rate swap agreements mature December 31, 1994.  

   The Company is exposed to credit loss in the event of non-performance
   by the other parties to the interest rate swap agreements; however, the
   Company does not anticipate non-performance by the counterparties. 
   Based on borrowing rates currently available to the Company for senior
   and subordinated loans with similar terms, maturities and prepayment
   options, the Company estimates that the fair value of its interest
   bearing debt and the related interest rate swap agreements is $124.6
   million as compared to the carrying amount shown on the balance sheet
   of $121.7 million.


6. SUBORDINATED NOTES

   Pursuant to a Note Agreement as amended and restated as of November 24,
   1992 (the Note Agreement), the Company issued to a group of insurance
   companies owned by Massachusetts Mutual Life Insurance Company,
   $44,450,000 face amount of Subordinated Notes (Notes) due October 31,
   2000.  The Notes are subordinated to the Senior Debt obligations, (see
   Note 5).  The Notes require semi-annual interest payments at a rate of
   14% on October 31 and April 30 of each year.  The Company may make
   optional prepayments of Notes, with a penalty, beginning November 1,
   1995.  The Note Agreement contains covenants requiring certain minimum
   financial tests and restrictions on capital expenditures, investments,
   indebtedness and dividends.  At December 31, 1993, the Company was in
   compliance with the terms of the Note Agreement.

   The mandatory principal repayment schedule for the Notes is as follows
   (000's):
                         1998      $14,800
                         1999       14,825
                         2000       14,825
                                   -------
                                   $44,450
                                    ======

7. SHAREHOLDER'S EQUITY
<TABLE>
<CAPTION>
   The following table summarizes the various series and classes of
   preferred and common stocks that are authorized, issued and outstanding
   as of December 31, 1993:

                                             Shares          
                                                  Issued and 
                                     Authorized   Outstanding    Amount
   <S>                               <C>          <C>          <C>     
   Preferred stock - non-voting;
    $10 par value:
      Series A - $15.00 non-cumulative,
        non-convertible                  1,350   
      Series B - $1.50 non-cumulative,
        non-convertible                186,500   
      Series C - $1.00 cumulative,
        non-convertible                 12,150      12,150     $121,500
      Series D - $.60 cumulative, 
        convertible:
          Class A                      161,523   
          Class B                       30,938      12,991      129,910
                                        ---------   --------- ---------
   Total                               392,461      25,141     $251,410
                                       =======     =======      =======


   Common stock - voting; $.10
    par value:
      Common shares                   212,461      162,873     $ 16,287
      Class A common shares            16,785       16,785        1,679
                                     ------------  ----------   -------

   Total                              229,246      179,658     $ 17,966
                                      =======      =======      =======
</TABLE>

   The outstanding preferred shares are redeemable, at the option of the
   Company, at $10 per share plus all accrued and unpaid dividends.  In
   the event of dissolution or liquidation, the preferred shareholders are
   entitled to receive these same amounts before any distributions are
   made to the common shareholder.  The Series D Preferred Shares are
   convertible, at the option of the shareholder, into common shares on
   a one-for-one basis.


8. COMMITMENTS

   Leases - The Company rents office space and certain computer and other
   equipment under leases expiring during the next 15 years.  At December
   31, 1993, the aggregate minimum annual rentals under noncancelable
   operating leases were as follows:


                 Years Ending               
                 December 31                
                 ------------                            

                   1994          $ 6,237,568
                   1995            4,406,666
                   1996            3,513,503
                   1997            2,573,471
                   1998            2,223,802
                   Thereafter     10,660,288
                                 -----------
                                 $29,615,298
                                 ===========                      

<PAGE>

                                              August 1994

Dear Oppenheimer Global Bio-Tech Shareholder:

   Last month, I sent a letter to let you know about some exciting changes
being proposed for your Fund.  A shareholder meeting has been scheduled
for September 19th, and all shareholders of record on July 15th are being
asked to vote either in person or by proxy.  You will find a notice of the
meeting and a proxy statement detailing the proposal enclosed for your
review.

What is being proposed?

   On June 16th, your Board of Trustees -- who represent you in matters
regarding your Fund -- recommended approval of the proposal to change
certain fundamental investment policies of the Fund to expand the
investment focus from global bio-technology stocks to global emerging
growth companies.

   We believe that small companies who do business globally are well-
positioned to take advantage of the dramatic changes affecting the world
markets today...and as these markets mature, the investment opportunities
should be very attractive.

   If the proposal is approved, your Fund's portfolio management team will
have the flexibility to invest in many emerging growth sectors worldwide,
which they believe will provide greater growth potential.  And some of the
risks associated with sector fund investing may be reduced by diversifying
the Fund's investments across different sectors.

How do you vote?

   No matter how large or small your investment, your vote is important,
so please review the proxy statement carefully.  To cast your vote, simply
mark, sign and date the enclosed proxy ballot and return it in the
postage-paid envelope today.

   If you have questions, please contact your financial advisor or call
us at 1-800-525-7048.

                                                                      
Sincerely,

Jon Fossel

P.S. Casting your vote is quick and easy, so please take a moment to complete 
the proxy ballot.




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