FRANKLIN MUTUAL SERIES FUND INC
497, 2000-05-03
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                            FRANKLIN TEMPLETON GROUP
                          777 Mariners Island Boulevard
                               San Mateo, CA 94404


May 3, 2000


Filed Via EDGAR (CIK #0000825063)
Securities and Exchange Commission
Judiciary Plaza
450 Fifth Street, N.W.
Washington, D.C.  20549-1004

         RE:      FRANKLIN MUTUAL SERIES FUND INC.
                  File Nos. 33-18516 and 811-5387

Ladies/Gentlemen:

Pursuant to Rule 497(j)  under the  Securities  Act of 1933,  this is to certify
that the forms of Prospectuses  and Statements of Additional  Information,  that
would have been filed under Rule 497(c) do not differ  from those  contained  in
Post-Effective  Amendment  No. 28 to the  Registration  Statement  on Form N-1A,
which was filed  electronically  with the Securities and Exchange  Commission on
April 27, 2000.

Sincerely yours,

FRANKLIN MUTUAL SERIES FUND INC.




/s/ David P. Goss
Counsel

DPG:ms

cc:  Mark H. Plafker, Esq.


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