<TABLE> <S> <C>
<ARTICLE> 6
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM THE
MUTUAL SHARES FUND JUNE 30, 2000 SEMI-ANNUAL REPORT AND IS
QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL STATEMENTS.
</LEGEND>
<CIK> 0000825063
<NAME> FRANKLIN MUTUAL SERIES FUND, INC.
<SERIES>
<NUMBER> 001
<NAME> MUTUAL SHARES FUND - CLASS A
<S> <C>
<PERIOD-TYPE> 6-MOS
<FISCAL-YEAR-END> DEC-31-2000
<PERIOD-END> JUN-30-2000
<INVESTMENTS-AT-COST> 5930906459
<INVESTMENTS-AT-VALUE> 6773790997
<RECEIVABLES> 214469996
<ASSETS-OTHER> 88787198
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 7077048191
<PAYABLE-FOR-SECURITIES> 90463360
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 24309011
<TOTAL-LIABILITIES> 114772371
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 5447539543
<SHARES-COMMON-STOCK> 63792789
<SHARES-COMMON-PRIOR> 67012191
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> (60531879)
<ACCUMULATED-NET-GAINS> 719591899
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 855676257
<NET-ASSETS> 6962275820
<DIVIDEND-INCOME> 51359644
<INTEREST-INCOME> 39380739
<OTHER-INCOME> 0
<EXPENSES-NET> (34438307)
<NET-INVESTMENT-INCOME> 56302076
<REALIZED-GAINS-CURRENT> 768607039
<APPREC-INCREASE-CURRENT> (794806486)
<NET-CHANGE-FROM-OPS> 30102629
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (22026778)
<DISTRIBUTIONS-OF-GAINS> (70094718)
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 7101911
<NUMBER-OF-SHARES-REDEEMED> (14951013)
<SHARES-REINVESTED> 4629700
<NET-CHANGE-IN-ASSETS> (887632194)
<ACCUMULATED-NII-PRIOR> 13620505
<ACCUMULATED-GAINS-PRIOR> 355649457
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> (21730634)
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> (36209105)
<AVERAGE-NET-ASSETS> 7278628127
<PER-SHARE-NAV-BEGIN> 20.38
<PER-SHARE-NII> 0.14<F1>
<PER-SHARE-GAIN-APPREC> (0.01)
<PER-SHARE-DIVIDEND> (0.37)
<PER-SHARE-DISTRIBUTIONS> (1.18)
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 18.96
<EXPENSE-RATIO> 1.13<F2>
<FN>
<F1>BASED ON AVERAGE WEIGHTED SHARES OUTSTANDING.
<F2>THE EXPENSE RATIO, EXCLUDING WAIVER AND PAYMENTS BY AFFILIATES IS 1.18%.
THE EXPENSE RATIO, EXCLUDING DIVIDEND EXPENSE ON SECURITIES SOLD SHORT IS
1.10%. THE EXPENSE RATIO, EXCLUDING DIVIDEND EXPENSE ON SECURITIES SOLD SHORT
AND WAIVER AND PAYMENTS BY AFFILIATE IS 1.15%. EXPENSE RATIOS ARE ANNUALIZED.
</FN>
</TABLE>
