<TABLE> <S> <C>


<ARTICLE>                     5
<LEGEND>
     This schedule contains summary financial information extracted from the
Form 10-Q for the quarter ended September 30, 2000 and is qualified in its
entirety by reference to such financial statements.
</LEGEND>
<CIK>                         0000829549
<NAME>                        ADVANCED TISSUE SCIENCES, INC.
<MULTIPLIER>                                   1,000

<S>                             <C>
<PERIOD-TYPE>                   9-MOS
<FISCAL-YEAR-END>                             DEC-31-2000
<PERIOD-START>                                JAN-01-2000
<PERIOD-END>                                  SEP-30-2000
<CASH>                                             34,298
<SECURITIES>                                        3,959
<RECEIVABLES>                                       1,539
<ALLOWANCES>                                            0
<INVENTORY>                                         5,693
<CURRENT-ASSETS>                                   46,648
<PP&E>                                             33,315
<DEPRECIATION>                                    (18,800)
<TOTAL-ASSETS>                                     66,641
<CURRENT-LIABILITIES>                               9,307
<BONDS>                                             7,043
                                   0
                                             0
<COMMON>                                              642
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<TOTAL-LIABILITY-AND-EQUITY>                       66,641
<SALES>                                             9,497
<TOTAL-REVENUES>                                   19,453
<CGS>                                               9,497
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<OTHER-EXPENSES>                                        0
<LOSS-PROVISION>                                  (10,392)
<INTEREST-EXPENSE>                                 (1,232)
<INCOME-PRETAX>                                   (21,240)
<INCOME-TAX>                                            0
<INCOME-CONTINUING>                               (21,240)
<DISCONTINUED>                                          0
<EXTRAORDINARY>                                         0
<CHANGES>                                               0
<NET-INCOME>                                      (21,240)
<EPS-BASIC>                                          (.36)
<EPS-DILUTED>                                        (.36)



</TABLE>



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