HELIX BIOMEDIX INC
10KSB, 1997-04-14
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U. S. SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

FORM 10-KSB

[X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE 
SECURITIES EXCHANGE ACT OF 1934 [No Fee Required]
    For the fiscal year ended      December 31, 1996   

OR

[ ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE 
SECURITIES EXCHANGE ACT OF 1934 [No Fee Required]
    For the transition period from____________ to 
______________


COMMISSION FILE NO. 33-20897-D

HELIX BIOMEDIX, INC.
COLORADO       84-1080717
2151 E. LAKESHORE DR., BATON ROUGE, LA 70808
(504) 387-1112


Securities registered pursuant to Section 12(b) of the 
Act:  NONE
Securities registered pursuant to Section 12(g) of the 
Act:  NONE

Check whether the issuer (1) filed all reports required 
to be filed by Section 13 or 15(d) of the Exchange Act 
during the past 12 months (or for such shorter period 
that the registrant was required to file such reports), 
and (2) has been subject to such filing requirements for 
the past 90 days.  YES [X]  NO [ ]

Indicate by check mark if disclosure of delinquent filers 
pursuant to Item 405 of Regulation S-B is not contained 
in this form, and no disclosure will be contained, to the 
best of registrant's knowledge, in definitive proxy or 
information statements incorporated by reference in Part 
III of this Form 10-KSB or any amendment to this Form 10-
KSB. [ ]

Registrant's revenues for the fiscal year ending December 
31, 1996: $10,838

As of December 31, 1996, there were 1,270,620 shares of 
common no par value stock of Helix BioMedix, Inc. issued 
and outstanding, and the aggregate market value of the 
common stock held by non-affiliates was approximately:  
$1,064,423  

DOCUMENTS INCORPORATED BY REFERENCE:   YES.  SEE INDEX ON 
PAGES 20 AND 21  

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EXHIBITS:   Indexed at Pages 21 and 22 

PAGES:  This Form 10-KSB consists of 23 pages, plus pages 
F-1 through F-13.

PART I

ITEM 1.  BUSINESS

(a)  General Development of Business

Helix BioMedix, Inc., formerly Cartel Acquisitions, Inc. 
("the Company"), was formed under the laws of the state 
of Colorado on February 2, 1988 to create a corporate 
vehicle to seek and acquire a business opportunity.  On 
March 20, 1989, the Company acquired 100% of the 
outstanding shares of Helix BioMedix, Inc., a Louisiana 
corporation, ("BioMedix of Louisiana") in exchange for 
shares of the Company's common stock representing a 
control interest in the Company.  The Company acquired 
all of the stock of BioMedix of Louisiana from Helix 
International Corporation ("Helix"), a Louisiana 
corporation founded in 1985.  BioMedix of Lousiana was 
incorporated on November 7, 1988 as a wholly owned 
subsidiary of Helix to develop therapeutic 
biopharmaceuticals for animal and human health care.

On June 19, 1989, having acquired BioMedix of Louisiana, 
the Company amended its charter to change its name to 
Helix BioMedix, Inc. All references herein to the Company 
refer to Helix BioMedix, Inc., the Colorado corporation, 
and its wholly owned subsidiary, Helix BioMedix, Inc. of 
Louisiana.

(b)  Description of Business During the Development Stage

Acquisition of Rights to the Lytic Peptide Technology

Since March 1989 the Company has been involved in the 
business of conducting research both internally and 
through a contract arrangement with Louisiana State 
University ("LSU").  Prior to its incorporation of 
BioMedix of Louisiana, Helix had started its research on 
lytic peptides (small bioactive proteins) in 1986, and in 
August 1987 entered into a collaborative "Antimicrobial 
Project" Agreement with LSU which had done pioneering 
exploratory research in this area.   Under the terms of 
the Agreement Helix provided funding for specific 
research support at LSU, Helix assumed responsibility for 
obtaining a patent position to protect the results of the 
research, and LSU and Helix agree to share equally in any 
future royalty income, and Helix retained the rights to 
commercialize the technology developed in the 
Antimicrobial Project.

Helix transferred to BioMedix of Louisiana in 1988 all of 
its rights and obligations in the Antimicrobial Project 
relating to the use of lytic peptides in animal and human 
health care.  Therefore, in March 1989 the Company 
acquired all of such rights for the purpose of further 
developing the technology and ultimately bringing 
commercial products to market.

Research and Management Agreement with Helix 
International Corporation

Concurrent with its acquisition of BioMedix of Louisiana, 
the Company entered into an agreement with Helix which 
provided that the scientific employees of Helix continue 
to conduct lytic peptide research in its laboratories, 
that Helix continue to support the LSU research under the 
Antimicrobial Agreement, that Helix continue to obtain 
the related patent coverage---all to be undertaken on a 
contract basis for the account of the Company.  Under the 
terms of the Agreement, Helix provided research 
scientists and technicians, laboratory and office 
facilities and all administrative services to the Company 
on a cost plus 15% basis.  This arrangement continued 
through February 1990.

Research and Management Agreement With University 
Research & Marketing, Inc.

In March 1990 the Company lacked adequate financial 
resources to continue its contract research activities, 
and Helix was also no longer able to provide financial 
support to the Company.  At that time Helix closed its 

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laboratory operations, and the Company's in-house 
research and development activities were curtailed 
pending availability of additional financing.  
Concurrently, the Company underwent a de-facto change in 
control wherein Helix agreed to sell to University 
Research & Marketing, Inc. ("URM") the majority of its 
controlling stock interest in the Company.  In connection 
with this action the Company entered into an agreement 
with URM, whereby URM would provide administrative 
services and continue to support the research at LSU in 
behalf of the Company for a flat fee of $20,000 per month 
plus patent and other out of pocket costs.  It was agreed 
that the Company would defer cash payment for such 
services until it was able to obtain additional corporate 
financing.  

URM continued to perform such services on behalf of the 
Company from March 1990 until August 1991.  Although 
research activities were maintained at a substantially 
lower level than in 1989, the patent prosecution was 
continued, and favorable corroboration of the early 
research  was obtained by scientists in outside 
universities (other than LSU) who evaluated several of 
the Company's proprietary lytic peptide compounds.  

Discontinuation of Reporting to the SEC and Cessation of 
Trading of the Company's Stock

From February 1990 until 1994 the Company was operated on 
an absolutely minimum budget for administrative costs 
because of the lack of operating capital.  Therefore, the 
Company was unable to continue the substantial expense 
and effort of filing quarterly 10-Q and annual 10-K (with 
audited financial statements) Reports with the SEC.  
Prior to 1994 the last report filed with the SEC was the 
Company's Report on Form 10-Q for the quarterly period 
ending September 30, 1989.  That Report is incorporated 
herein by reference as Exhibit 13-a.  Until 1994 the 
Company had not been current nor in compliance with the 
reporting requirements for public companies pursuant to 
Section 13 or 15(d) of the Securities Exchange Act of 
1934 Company during the period of non-reporting to the 
SEC.  In late 1988 and throughout 1989 the Company's 
common stock was actively traded in the over-the-counter 
market as a "penny stock" listed in the pink sheets.  
Several brokerage firms acted as market makers in the 
stock.  After State and Federal securities regulatory 
agencies drastically curtailed operations of penny stock 
brokers in 1989 and 1990, and after the Company ceased to 
make financial statements publicly available, trading of 
the Company's stock substantially discontinued until 
1994.  This is discussed further in Item 5 of Part II of 
this Report.

Management Control of the Company Returned to Helix 
International Corporation

URM was unable to fulfill its commitment to purchase from 
Helix the controlling interest in the Company's common 
stock.  In July 1992, de-facto control of the Company was 
returned to Helix by the shareholders of the Company, at 
which time Helix, URM, and Mr. Keith P. Lanneau 
(returning as President and CEO of the Company) and 
several other substantial shareholders committed to a 
plan of action for revitalizing and restructuring the 
Company.

Plan for Restructuring the Company

By mid 1992 it was the belief of the major shareholders 
of the Company that the Company's proprietary lytic 
peptide technology and the associated patent estate and 
the gradually emerging market potential for 
biopharmaceuticals had developed to a point which 
encouraged and demanded renewed corporate vigor.  
Management recognized that the Company should undertake a 
major strategic and financial restructuring to strengthen 
itself and to move aggressively toward commercialization 
of its technology base.  A restructuring plan was adopted 
with the following objectives which have been attained or 
are currently in the process of implementation as 
follows:

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<PAGE>

(a)  Several key shareholders to provide interim funding 
to maintain the Company's activities during the 
restructuring.

Key shareholders have done this on a month-to-month basis 
since August 1991 to the present time.  The Company 
believes it can rely upon a continuation of this funding 
until permanent private and/or public financing is 
obtained.

(b)  Management to be strengthened by new outside 
Directors.

In March 1993 the Company entered into an agreement with 
the Louisiana Partnership for Technology and Innovation 
("LAPTI") to obtain assistance in  implementation of the 
Company's restructuring plan and in the development of a 
program for selective licensing of the Company's 
technology.  In consideration of these services to be 
rendered, the Company issued 8,000 shares of its common 
stock to LAPTI in May 1993.  An officer and staff member 
of the Partnership, Mr. Michael K. Marcantel, joined the 
Company's Board of Directors and since 1993 has served as 
Vice President, Secretary-Treasurer.  He spends 
approximately 20% of his time assisting the Company's 
President in the restructuring initiatives discussed 
herein.

In December 1993 Dr. Donald R. Owen joined the Company as 
a Director and Vice President and Chief Scientist, 
bringing high level expertise to the Company in its 
fields of technical endeavor.

In October 1994 Mr. Thomas L. Frazer joined the Company 
as a Director with the specific mission of assisting 
management with its restructuring plan.  Access to Mr. 
Frazer's extensive business experience and financial 
expertise constitute an important step in further 
strengthening company management.  In mid 1995 the board 
of directors designated Mr. Frazer as Chief Financial 
Officer for the Company.

(c.)The Agreements with LSU to be renegotiated and 
novated to the benefit of the parties involved.

In March 1993 the Company, Helix, URM, and Helix 
Phytonetix, Inc. (a related company) entered into a 
novated Agreement of Settlement with LSU which releases 
all the parties from any defaults arising from their 
former respective agreements.  Ownership of the lytic 
peptide technology, formerly jointly owned by LSU and 
Helix (with the Company as assignee of the Helix 
interest) is now definitively clarified.  Under the new 
Agreement five U.S. patent applications (and their 
foreign counterparts), which have been prosecuted by 
Helix, URM, and the Company, are now the property of LSU.  
Pursuant to the new Agreement, the Company was granted by 
LSU a world-wide exclusive license to the technology of 
the lytic peptide patent estate with respect to all 
potential uses except in the area of plant technology.  
Additionally, the Company was granted a conditional 
right, without further funding from the Company, to 
obtain a license to certain  future lytic peptide 
technology which LSU may develop.

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<PAGE>

(d)  Stepped up development and prosecution of the patent 
estate.

In March 1994 the Company discharged the patent law firm 
which had previously handled prosecution of patent 
matters relating to the lytic peptide technology.  (See 
Item 3 herein)  The Company retained another large patent 
law firm, which it believes is fully qualified to develop 
the patent estate.  The Company is actively working with 
this law firm, as well as with several patent law firms 
in foreign countries to achieve the final issuance of 
several U.S. and foreign patents during 1997.  As soon as 
further financing is available, the Company is prepared 
to file additional patent applications on its peptides 
and drug delivery formulations, based on new proprietary 
bioactive compounds, which are outside the scope of the 
past and present agreements with LSU. 

(e)  Strengthen in-house scientific expertise and obtain 
enhanced capability to produce the Company's proprietary 
peptides and to develop formulated drug delivery vehicles 
for same.

In late 1993 the Company entered into negotiations with 
Therapeutic Peptides, Inc. ("TPI"), a firm located in New 
Orleans, LA.  In the Registrant's December 31, 1994 10-
KSB Report (Exhibit 13-f) it was disclosed that the 
Company and TPI were considering a plan to merge TPI into 
Helix BioMedix, contingent upon the latter's success in 
completing its first step private financing initiative to 
raise $500,000 as bridge funding.  The Company is 
currently deliberating with four separate corporate and 
institutional groups considering substantial private 
investment in the Company.  However, during the latter 
part of 1995, the Boards of Directors of Helix BioMedix 
and TPI concluded that the present interests of both 
companies are better served by a contractural strategic 
alliance between the parties than by a merger of the 
corporations.  On November 10, 1995 the Company and TPI 
reached agreement on such an alliance and executed a 
"Cooperative Endeavor Agreement" which closely links the 
parties in a joint initiative to further enhance the 
Company's patent estate and to commercialize the 
Cytoporin technology.

Dr. Donald R. Owen, Chief Scientist and a director of the 
Company, serves as President and Scientific Director of 
TPI.  Since 1993 TPI has utilized its scientific staff 
and well equipped laboratory facilities to synthesize and 
further evaluate the Company's lytic peptides.  During 
1995 and 1996 scientists at TPI developed new "third 
generation" derivatives of the Company's Cytoporin 
peptides which will further enhance the Company's patent 
estate.  Several of the new peptides, as well as earlier 
patented Cytoporins, all show excellent promise as lead 
compounds for pre-clinical and clinical development of 
new drugs. 

(f) Remove the Company's common stock from its previous 
"penny stock" status.

As set forth in Item 4 (Part I) of this Report, on 
December 29, 1993 at an Annual Meeting of its
Shareholders the Company effected a 500:1 reverse 
split of its outstanding shares of Common Stock.  With 
only 1,270,620 shares now outstanding, the stock (as set 

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<PAGE>

forth in Item 5-Part II herein) has resumed limited 
trading in the low "dollars", rather than "penny", range.  
This will facilitate the Company's future efforts to 
attract market makers and retail brokers to support 
trading of the Company's securities.

(g) Place the Company's financial reporting on a current 
basis and resume compliance with the SEC public company 
reporting requirements.

During the third quarter of 1994 the Company filed those 
Form 10-KSB and 10-QSB reports necessary to bring it 
current and in compliance with SEC reporting 
requirements.

Audited financial statements were prepared for the fiscal 
years ending December 31, 1989, 1990, 1991, 1992, and 
1993.  These statements were incorporated in a Form 10-
KSB report for the period ending December 31, That report 
was filed September 30, 1994 concurrently with the filing 
of Form 10-QSB reports for the first and second quarters 
of1994.  The Company also filed with the SEC its 1994 
third quarter 10-and December 31, 1994 10-KSB reports on 
a timely basis.  All quarterly 10-QSB and 10-KSB reports 
for 1995 and 1996 have been filed on a timely basis. The 
aforesaid reports are incorporated herein by reference as 
Exhibits 13-a through 13-m.  With the present filing of 
this Form 10-KSB report for the fiscal year ended 
December 31, 1995, the Company has been in full 
compliance with SEC public company reporting requirements 
with timely filing of required reports for the last 
thirty (30) months.   

(h)  Prepare a well documented five year Business Plan 
for the Company.

As a major component of its restructuring initiative, 
during the last two years the Company developed a five 
year Business Plan which is periodically updated to 
reflect advances in the state of the Company's technology 
platform.  The strategic elements of this Plan, which the 
Company believes are prudently consistent with the 
Company's probable ability to attract capital resources, 
will in the near future be reported in summary form to 
the Shareholders and to the public investing community. 

(i)  Resume a program of financial and information 
reporting to the Shareholders.

As soon as practicable after filing of this 1996 10-KSB 
report the Company plans to resume formal communications 
with its Shareholders by means of regular meetings, 
newsletters and/or quarterly and annual reports to the 
Shareholders.

(j)  Obtain adequate outside private capital funding to 
place the Company in sound financial condition to execute 
its Business Plan.

A primary, and necessary, objective of the Company's 
restructuring efforts has been to reach a point where 
adequate private capital funding can be attracted to 
supplement the earlier, limited public financing and to 
move the Company out of its development stage by 
commercializing the technology base.  The Company 

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<PAGE>

believes such financing will enable it to enter into 
strategic alliances and licensing agreements to produce 
both capital and revenues and to introduce its first 
products to the marketplace within the next two years.

Given the availability of current financial reporting, 
recent advances in development of its technology, and the 
aforesaid Business Plan, during 1996 the Company made 
presentations to potential private capital sources, 
including both venture capital groups and 
biotech/pharmaceutical companies interested in the 
Company's technology.  Definitive discussions are now 
underway with several such groups.  During 1997 
implementation of the financing initiatives is first 
priority for the Company's management.

(k)  Develop a network of retail brokers to re-establish 
an active trading market in the Company's securities.    

Pursuant to completion of the restructuring initiatives 
(i) and (j) described above, Company management will 
undertake to interest a group of small-to-medium size 
brokerage firms in becoming retail market makers in the 
Company's common stock.  This will require (1) current 
SEC reports, (2) a summary of the Company's current 
Business Plan, (3) re-establishment of news flow to 
shareholders, and (4) evidence of good financial 
viability through successful completion of the Company's 
on-going initiative to attract private capital.

During the latter half of 1997 the Company believes it 
will develop an active market for its securities.  This 
will provide liquidity for the present public 
shareholders as well as lay the groundwork for future 
public financing by the Company. 

Investment in Research and Development

The Company's direct investment in research and 
development of its "Cytoporin" (i.e., lytic peptide) 
technology has aggregated $1,915,872 since Registrant's 
inception (November 7, 1988) to December 31, 1996.  Of 
this sum an amount of $329,053 has been capitalized as 
the legal costs incurred in patent prosecution,  $200,000 
capitalized as a cost paid by promissory note to Helix 
International Corporation to acquire the Antimicrobial 
Technology at Registrant's inception, and $25,000 paid in 
common stock issued (10,000 shares) as partial 
consideration for Antimicrobial Technology developed for 
the Company by TPI prior to confection of the Cooperative 
Endeavor Agreement in November 1995. The balance of 
$1,361,819 has been expensed as R & D costs as they were 
incurred by the Company.  The Company's total investment 
in R & D and other operating and interest expenses to 
develop its Cytoporin technology has aggregated 
$3,110,122 since Registrant's inception through December 
31, 1996. 

To the best of Registrant's knowledge, prior to November 
7, 1988 Helix International had invested approximately 
$839,400 in research and development (excluding patent 
costs) on the lytic peptide technology.  In addition to 
the approximately $3,949,522 invested by Registrant and 
Helix International Corporation to develop the technology 
base, LSU, several other universities, TPI, and several 
other companies have expended substantial sums of their 
own in exploring potential applications of the Company's 
Cytoporin technology.

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Potential for Commercialization of the Company's 
Technology

The Company's technology is based on the discovery that 
its proprietary bioactive Cytoporin compounds (lytic 
peptides) have the ability to destroy a broad spectrum of 
bacteria, protozoa, fungi, and viruses which cause 
pathogenic disease conditions in animals and humans.  
Some of the Cytoporins have demonstrated activity as 
growth factors to promote wound healing and to cause 
proliferation of white blood cells which are subject to 
destruction by autoimmune diseases such as AIDS.  Certain 
Cytoporins, in in-vitro tests, have shown potential 
applications as chemotherapeutic agents in cancer 
therapy.

With the on-going critical concern in scientific and 
medical circles about the exploding emergence of 
antibiotic resistant bacteria, the use of Cytoporins as 
adjuvants or enhancers to boost the effect of existing 
antibiotics against resistant bacterial strains opens an 
important new realm of possible pharmaceutical 
applications for the Company's Cytoporin compounds.

The cost and time of bringing new drugs to market 
essentially mandates that the Company seek strategic 
alliances and licensing arrangements with larger, well 
financed companies to bring the Cytoporins through 
arduous and expensive clinical trials before they find 
commercial applications as prescription drugs.

While the Company is pursuing the long term introduction 
of high potential prescription drugs through a program of 
strategic partnering, it will concentrate in-house 
efforts on the near term introduction of proprietary 
products in the area of topical antiseptics and 
industrial disinfectants.

Impact of Regulatory Factors

The enormous cost and time of bringing prescription drugs 
through the FDA regulatory gauntlet of clinical trials 
and approvals is a factor that virtually assures the 
Company must seek well financed strategic partners for 
such initiatives in the pharmaceutical or biotechnology 
industries.  For this reason the Company is developing, 
for near term market introduction, certain non-drug 
products subject to less stringent regulatory hurdles 
posed by the FDA and/or environmental protection 
agencies.


Company's Proprietary Position and Competition

The Company believes it is establishing a strong patent 
position (both U.S. and foreign) with respect to the 
compositions of matter and use of its Cytoporin peptides.   
There is increasing interest in the biopharmaceutical 
industry in the potential for lytic peptides as 
therapeutic drug agents.  To the best of the Company's 
knowledge there are at least four other U.S. companies 
actively working in the field.  They have greater 
financial resources available to them.  However, 
Registrant believes its early dates on patents and patent 
applications are a major competitive asset, as is the 
proprietary technical and product know-how which it has 
gained  over a period of eight years.  The Company's five 
year Business Plan embraces a concept of long term 
strategic partnering and introduction of near term 
proprietary products to niche markets.  Company 
management believes the Plan takes full cognizance of the 
emerging presence of well financed competitors in the 
general field of endeavor.  

ITEM 2.  PROPERTIES

The Company maintains its offices in office space 
provided by the Company's President.  The President is 
paid $200 per month for rent of this space and is 
reimbursed for out-of-pocket expenses for telephone use, 
postage, and other general office expenses.  These rent 
payments for rent and other Company offices expenses are 


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not made in cash, but are accrued as an account or note 
payable to the President (or an affiliated company) until 
the Company is in a position to pay these expenses on a 
cash basis.  The Company offices are located at 2151 East 
Lakeshore Dr., Baton Rouge, Louisiana 70818.  The 
telephone number is (504) 387-1112, and the Fax Number is 
(504) 338-9727.

Synthesis and testing of the Company's proprietary 
Cytoporin compounds (lytic peptides) are conducted at the 
laboratories (approx. 3000 sq. ft. ) of Therapeutic 
Peptides, Inc.(TPI) in Harahan, LA.  Dr. Donald R. Owen 
is President of TPI and is a Vice President and Director 
of Helix BioMedix, Inc.  The Company utilizes the TPI 
laboratories under the terms of the Cooperative Endeavor 
Agreement between the Company and TPI.  The Company 
reimburses TPI in cash for such contract research 
conducted for the account of the Company.


ITEM 3.  LEGAL PROCEEDINGS

On July 27, 1994 the Company, as a Co-Plaintiff, filed a 
suit against Pravel, Hewitt, Kimball & Krieger, P.C., ET 
AL, as defendants, in the Civil District Court, Parish of 
Orleans, State of Louisiana.  Other Co-Plaintiffs with 
the Company were Helix BioMedix, Inc. (LA), Helix 
International Corporation (a Louisiana corportion), Helix 
Phytonetix, Inc. (a Louisiana corporation), and 
University Research & Marketing, Inc. (a Louisiana 
corporation).  This litigation was settled in 1996.

The Defendants in the above proceeding were a patent law 
firm (or members of same) which previously represented 
and performed professional services for the Plaintiffs.

Plaintiffs alleged that Defendants committed legal 
malpractice through their failure to file or timely file 
certain patent applications in certain foreign countries, 
that said patent applications were with respect to 
technology licensed to Plaintiffs by Louisiana State 
University, and that Plaintiffs were damaged by present 
and future diminution of the value of the patent estates 
of Plaintiffs.

The Plaintiffs sought relief through money judgment for 
damages.  In May 1996 the suit was settled out of court.  
The Company received a portion of the net settlement 
proceeds paid to the joint Plaintiffs.  (See Note 6 to 
the Financial Statements herein).

Registrant has no liability in connection with the above 
suit which has been settled, and Registrant is not aware 
of any threatened legal proceeding to which the 
Registrant is a party.


ITEM 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY 
HOLDERS

No matters were submitted to a vote of security holders 
during 1996.  The most recent Annual Meeting of the 
Shareholders of Registrant was held on December 29, 1993.  
There was no proxy solicitation for the meeting.  Exhibit 
No. 22 incorporated by reference in this Report is a copy 
of the Notice of the Meeting timely forwarded to the 
Shareholders.   A quorum was present and voting and there 
was a unanimous vote in favor of each matter voted upon 
as follows:

Directors elected or re-elected to constitute the Board 
of Directors.

Amendments to the Articles of Incorporation to (i) Effect 
a 500:1 Reverse Stock Split, and (ii) Reduce the Number 
of Authorized Shares, all as set forth in Exhibit No. 22 
incorporated by reference in this Report.

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Exhibit No. 22 also includes a copy of a Notice to 
Shareholders dated March 11, 1994 requesting them to 
contact Registrant's Stock Transfer Agent to exchange 
their stock certificates pursuant to the shareholder 
approved 500:1 reverse stock split.


PART II

ITEM 5.  MARKET FOR COMMON EQUITY AND RELATED STOCKHOLDER 
MATTERS

(a)  Principal Market or Markets

The Registrant's Shares of common stock are traded on the 
over-the-counter market.  Registrant ceased to be 
compliant with SEC reporting requirements in 1990, and 
there were only limited and sporadic trades of 
Registrant's securities, as "penny stock" from 1990 to 
1994.   After the 500:1 reverse stock split described in 
Item 4. of Part I of this Report, Registrant's stock 
(formerly symbol HXBI on the pink sheets) was reported in 
April, 1994 under the new stock symbol, "HXBM", on the 
electronic bulletin board of NASDAQ Market Operations.  
Since Registrant continued to be non-compliant with SEC 
reporting requirements until September 30, 1994, only 
limited trading of Registrant's stock had taken place in 
1994.  Based on information received from one of two 
Market Makers for Registrant's stock, during 1995 and 
1996 there has been a continuation of very limited and 
sporadic trading of Registrant's stock, with total 
transactions aggregating less than 10,000 shares during 
1996.  In the ninety day period prior to date of this 
Report the bid/ask quote has remained at $1.00 per share 
bid and $2.50 per share asked. The foregoing prices are 
believed to be representative inter-dealer quotations, 
without retail markup, markdown or comnmissions, and may 
not represent actual transactions.

Registrant believes that a non active market for its 
securities will continue to exist until such time as (1) 
Registrant promulgates to the public news of the 
Company's restructuring program and recent advances in 
development of its technology and (2) until the Company, 
now fully current in it SEC reporting, obtains a network 
of retail brokers to re-establish an active trading 
market for the stock, all as discussed in Item 1 of Part 
I of this Report.  Management believes this will occur 
during the latter half of 1997.

(b)  Approximate Number of Holders of Common Stock

The number of holders of record of Registrant's no par 
value common stock at December 31, 1996 was approximately 
600.  Registrant estimates and believes there are 200 to 
500 additional shareholders holding stock in "street 
name" in brokerage accounts.

(c)  Dividends

Holders of common stock are entitled to receive such 
dividends as may be declared by the Registrant's Board of 
Directors.  No dividends have been paid with respect to 
the common stock since Registrant's inception, and no 
dividends are anticipated to be paid in the foreseeable 
future.

ITEM 6.  MANAGEMENT'S DISCUSSION AND ANALYSIS OR PLAN OF 
OPERATION

(a)  Plan of Operation

The Company's general plan of operation is outlined in 
Item 1 of Part I of this Report.  The Company has 
maintained operations since 1990 primarily with limited 
capital provided by loans from key Shareholders.  A major 
strategic and financial corporate restructuring 
initiative has been undertaken since 1993.  The details 
of this program are set forth in Item 1 of Part I herein.  
The Company believes it is now prepared to implement a 


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<PAGE>

Business Plan providing for both near term and long term 
product introductions.  At the present time the Company 
is actively seeking additional capital through private 
sector financing.  Such financing will be used to bring 
the Company to continuing economic viability from 
commercially profitable operations.  This plan 
contemplates revenues from licensing and strategic 
alliances for long term development of prescription 
pharmaceutical products as well as introduction within 
the near term of products subject to less regulatory 
restraints.  It is expected by management that 
achievement of projected progress milestones will 
establish the Company as a financially viable 
biotechnology firm with substantial public investor 
support.

(b)  Management's Discussion and Analysis

During the two fiscal years ending December 31, 1993 and 
December 31, 1994, while the Company was instituting the 
restructuring program discussed in this report, the cost 
of operations was held to a minimum.  Continuing through 
1995, in the absence of revenues operating losses were 
held to approximately $47,000 per quarter, of which 
approximately $14,000 per quarter represents interest 
accrual rolled into the principal of loans from 
shareholders.  Administrative costs were controlled at a 
low level by the fact that only the Company's President 
was a full time employee.  During this period the company 
substantially enhanced its patent prosecution with an 
investment of nearly $11,000 per quarter.  In house 
research and development has been placed in a holding 
pattern, with no funds of the Company expended in this 
area.  However, evaluation and product development with 
the Company's Cytoporin compounds has continued on an 
accelerated basis at Therapeutic Peptides, Inc.

During 1996 operations continued to be funded by 
additional loans from shareholders in the amount of 
approximately $236,000.  More significantly, at December 
31,1996 the Company's balance sheet was substantially 
improved by the conversion of approximately $111,000 in 
debt into common stock.  This is indicative of the 
continuing confidence of management and key shareholders 
in the prospects for the Company's future.

Over the past year operating losses increased to an 
average of approximately $82,500 per quarter, of which 
approximately $16,500 per quarter represents interest 
accrual on loans from major shareholders.  Conversion 
into stock of approximately $111,000 in debt at December 
31, 1996, along with further substantial conversion of 
debt to key shareholders expected in 1997, should greatly 
reduce future interest burden.  The main source of 
increase in operating expense in 1996 over the prior year 
came from stepped up R & D expense.

In 1996 full implementation of the alliance between the 
Company and TPI through the Cooperative Endeavor 
Agreement confected in November 1995 strengthened the 
Company's capability to expand its patent estate and 
bring the Cytoporin technology to commercial fruition.  
With Research and Development expenditures of $133,500 in 
1996 the Company greatly accelerated the development of 
its technology platform.  During the year the development 
and testing of more active and selective peptides 
produced data which has been particularly valuable in the 
Company's dialogue with potential strategic alliances in 
the pharmaceutical and biotechnology fields.  

In the second quarter of 1997 the Company expects to 
complete its present near term initiative to raise 
capital through private financing.  In its first phase of 
financing, the Company is seeking to raise $500,000 as 
bridge capital to fund operations for a period of twelve 
to sixteen months at the level projected in the Business 
Plan.  Management believes it is now critically important 
to increase spending in order to (i) step up further 
development of the patent estate, (ii) fund the vital 
product development work at TPI, (iii) aggressively 
proceed with seeking strategic alliances, (iv) maintain 
public reporting of company finances and operations, and 
to (v) conclude successfully an effort to bring further 
equity capital funding to the Company through a major 
private placement.  Management believes after the bridge 
capital funding that an additional $2.0 million added to 

11

<PAGE>

the Company's equity capital base will permit the Company 
to emerge profitably from its development stage during 
the next two to three years.  Success in its efforts to 
consummate the planned private capital financing steps is 
now essential to the Company's completion of the 
restructuring program which it has undertaken.

During the last quarter of 1995 operations were 
highlighted by two important technical developments.  
These were reported in two News Releases which were both 
nationally and internationally promulgated through the 
media and Business Wire services.  Copies of these 
releases were included as exhibits in Registrant's 1995 
10-KSB Report, which is incorporated by reference herein 
as Exhibit 13-j.  In 1996 these News Releases have 
resulted in inquiries from over 20 international 
pharmaceutical and biotechnology companies.  The 
inquiries about the Cytoporin technology have already 
developed for the Company on-going dialogue with several 
potential candidates for strategic alliances.

In the third and forth quarters of 1996 the Company 
entered into confidential Material Transfer Agreements 
with two such pharmaceutical companies for collaborative 
test programs on selected Cytoporin lead compounds.  As 
disclosed in the News Releases, Management believes the 
Company's Cytoporin compounds may play a vital role in 
addressing the current health care crisis related to 
rapid and continuing emergence of antibiotic resistant 
bacteria and other pathogens.  Also, the announced 
issuance of two important European patents, under 
exclusive world-wide license to the Company, will 
materially strengthen the Company's competitive position 
and enhance the Company's posture in its initiatives to 
acquire financing and to establish alliances in the 
biopharmaceutical industry.

The Company's common stock, which is traded OTC under the 
symbol "HXBM" on the NASDAQ bulletin board, continues to 
trade only sporadically and in small transactions.  
Management believes this will continue to be the case 
until the Company completes its first step of bridge 
financing and thereby permit expanded operations under a 
sound and viable Business Plan.  As a step precedent to 
resumption of active public trading of the common stock, 
in late 1995 the Company made application for and 
obtained published coverage of the Company in Standard 
and Poor's Corporation Records.  This coverage continues 
on a current basis.

Pending completion of ongoing financing initiatives, 
current operations of the Company continue to be financed 
by loans from and/or investments by several key 
shareholders. 

ITEM 7.  FINANCIAL STATEMENTS

Please see Pages F-1 through F-13.

The following Financial Statements are filed as part of 
this report:
                                                   Page
Report of Independent Certified Public Accountants  F-1

Balance sheet as of December 31, 1996               F-2

Statement of Operations for the periods ending 

December 31, 1995 and December 31, 1996 and 
for the period from inception (November 7, 1988)
to December 31, 1996                                F-3

Statement of Stockholders' Equity (Deficit) 
for the period from inception (November 7, 
1988) to December 31, 1996                     F-4 to F-6


12

<PAGE>

Statements of Cash Flows for the period 
from inception (November 7, 1988) to 
December 31, 1996                              F-7 to F-8

Notes to Financial Statements                 F-9 to F-13

All schedules have been omitted, as the required 
information is inapplicable or the information is 
presented in the financial statements or the notes 
thereto.


ITEM 8.  CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON 
ACCOUNTING AND FINANCIAL DISCLOSURE

There have been no disagreements between the Registrant 
and its independent accountants on any matter of 
accounting principles or practices or financial statement 
disclosure since the Registrant's inception.

13

<PAGE>

PART III

ITEM 9.  DIRECTORS, EXECUTIVE OFFICERS, PROMOTERS AND 
CONTROL PERSONS; COMPLIANCE WITH SECTION 16(a) OF THE 
EXCHANGE ACT

(a)  The Directors and Officers of the Registrant are as 
follows:

Name:  Keith P. Lanneau
Age:  71
Position:  President, CEO, and Director
Tenure as Officer or Director:  March 15, 1989 
to March 10, 1990 as President, CEO, and Director; 
November 13, 1991 to July 10, 1992 as a Director; and  
July 10, 1992 to present as President, CEO, and Director.

Name:  Thomas L. Frazer
Age:  51
Position:  Director
Tenure as Officer or Director:  October 27, 1994 to 
present as a Director

Name:  Robert J. Love, M.D.
Age:  48
Position:  Vice President and Director
Tenure as Officer or Director:  March 15, 1989 to March 
10, 1990 as a Director; September 14, 1991 to July 10, 
1992 as a Director; July 10, 1992 to December 31, 1993 as 
a Director; and December 31, 1993 to present as Vice 
President and a Director.

Name:  Michael K. Marcantel
Age:  48
Position:  Vice President, Secretary-Treasurer, and 
Director
Tenure as Officer or Director:  May 5, 1993 to present. 

Name:  Donald R. Owen, Ph.D.
Age:  52
Position:  Vice President , Chief Scientist, and Director
Tenure as Officer or Director:  December 29, 1993 to 
present.

A brief description of the business experience of each of 
the above Directors and Officers of Registrant is set 
forth below:

Mr. Lanneau was founder of Helix Biomedix, Inc. (of 
Lousiana) in 1988, which company was acquired by 
Registrant on March 20, 1989.  Registrant, formerly named 
Cartel Acquisitions, Inc. (a Colorado corporation) then 
changed its name to Helix BioMedix, Inc. (of Colorado).  
Mr. Lanneau has served full time as Chief Executive 
Officer of Registrant during the periods of tenure shown 
above.  He holds a B.S. degree in Physics from the 
Massachusetts Institute of Technology and an M.B.A. 
degree from Harvard.  He is the author of numerous 
patents and publications and was a scientist and research 
director with Exxon Research and Engineering for eleven 
years from 1949 to 1960.  For some of his notable 
scientific work with Exxon he was awarded the Senior 
Moulton Medal of the British Institution of Chemical 
Engineers in 1959.

14

<PAGE>

Prior to his association with Registrant Mr. Lanneau, 
after 1960 had extensive experience as a scientist-
businessman, having been the founder, Chief Executive 
Officer, Director, and/or Principal Scientist of several 
high technology companies.  He was a founding director of 
Louisiana's Gulf South Research Institute, a non-profit 
multi-disciplinary contract research organization.  He 
was a member of its Board of Directors and Executive 
Committee from 1965 to 1985 and served a two year term as 
Chairman of the Board.  Mr. Lanneau was a founding member 
of the Louisiana Partnership for Technology and 
Innovation in 1988.  Throughout his business and 
professional career, he has actively served on the boards 
of various local and statewide civic organizations within 
Louisiana.

In addition to his present duties as President/CEO and 
Director of the Company Mr. Lanneau is an active 
scientific collaborator with Dr. Donald R. Owen, and he 
assumes primary responsibility for technical interfacing 
with patent attorneys and those outside companies with 
whom the Registrant seeks collaborations and strategic 
alliances.

Mr. Frazer, a practicing CPA,  is a prominent business 
executive in Baton Rouge, LA.  He was a founding director 
of a commercial bank and has served on the board of 
directors of a number of business corporations.  He was 
chairman of the board of a $50,000,000 computer software 
company.  He is a professional consultant and expert in 
company acquisitions, restructuring programs, and 
financial reorganizations. As such, Mr. Frazer's recent 
addition to the Company's board of directors constitutes 
an important milestone in the Company's initiative to 
strengthen its management organization.

Dr. Love is a Canadian citizen and resident of Vancouver, 
British Colombia.  He holds a B.S. degree in biology and 
received his Doctorate in Medicine from the University of 
Alberta.  From 1986 to 1988 he served as President and 
Director of Esstra Industries Corporation, a Canadian 
public company with interests in several high technology 
ventures.  During his association with Helix BioMedix, 
Inc. he has been active in developing interest in the 
company's technology at medical research clinics in 
Canada.  In his medical practice in Vancouver he 
specializes in environmental medicine and immunology.  He 
is a member of the American Academy of Environmental 
Medicine.  

Mr. Marcantel is a Vice President of the Louisiana 
Partnership for Technology and Innovation ("LAPTI") and 
has held that position since 1988.  Prior to joining 
LAPTI he held various management positions from 1977 to 
1988 with Gulf South Research Institute where he was 
responsible for contract administration and intellectual 
property (patents) management.  He holds a B.S. degree in 
Business Administration from Louisiana State University.

LAPTI, a private, non-profit successor to Gulf South 
Research Institute supported by both State and private 
funding, assists in the formation and/or development of 
new technology based industries within the State of 
Louisiana.  LAPTI makes small seed capital investments in 
and/or contributes expertise in strategic and financial 
planning and management assistance to its "portfolio" 
companies.  As an officer and senior staff member of 
LAPTI, Mr. Marcantel presently serves on the Board of 
Directors of several high technology companies based in 
Louisiana.  In behalf of LAPTI, which holds a minority 
equity interest (approx. 1%) in Registrant, he spends 
approximately 20% of his time on his activities as an 
Officer and Director of Helix BioMedix, Inc.  Mr. 
Marcantel is a member of the Technology Transfer Society, 
Licensing Executives Society, and the National Contract 
Management Association.

15

<PAGE>

Dr. Owen holds a B.S. degree in Pre-Medicine and M.S. 
degree in Chemistry.  He obtained his Ph.D. in Chemistry 
from the University of Houston.  He has served on the 
faculties and staff of the University of Southern 
Mississippi, the University of Utah, and Tulane 
University.  Dr. Owen has numerous publications and 
extensive academic and industry research experience in 
several fields including polymer chemistry, biomaterials 
science, biomedical engineering, cosmetic and 
pharmaceutical formularies, and computer-aided rational 
design of bioactive peptides and proteins.

After serving six years as a Senior Scientist with Gulf 
South Research Institute, in 1987 Dr. Owen founded 
Biosouth Research Laboratories, Inc. ("BRL") in New 
Orleans as a private, contract research laboratory 
specializing in development of pharmaceutical and 
cosmetic formularies.  He is also founder and President 
of Biosyn, Inc., a manufacturer of specialty products for 
the cosmetic and pharmaceutical industries.  He is 
President of Vital Assist, Inc., another high technology 
company doing pioneering research on development of 
medical device organ perfusion systems for use in organ 
transplant centers and in the transport and preservation 
of donated human organs. Both of these latter two 
companies are "spin-outs" from technologies developed by 
Dr. Owen in his research company, BRL.  In 1992 a third 
"spin-out" (Therapeutic Peptides, Inc. ("TPI") was formed 
by BRL and Dr. Owen to focus on research in peptide 
chemistry and to collaborate with Helix BioMedix, Inc. in 
the synthesis and testing of the proprietary Cytoporin 
(lytic peptide) compounds of BioMedix.

At the present time Registrant and TPI are working 
jointly to commercialize the Cytoporins under the terms 
of the Cooperative Endeavor Agreement adopted by them in 
November 1995.  Dr. Owen is President and Scientific 
Director of TPI.  In December 1993 he joined Helix 
BioMedix, Inc. as a Director and Vice President and Chief 
Scientist. Dr. Owen is presently an Adjunct Professor of 
Materials Science and Bioengineering at the University of 
New Orleans.  He is a member of the American Chemical 
Society, Society of Biomaterials, and the International 
Society of Artificial Organs.  In 1993 he received 
recognition from the Louisiana Partnership for Technology 
and Innovation as the State's top "Innovator of the 
Year".

All Directors of the Registrant will hold office until 
the next annual meeting of the shareholders and hold 
office until their successors have been elected and 
qualified.

The Officers of the Registrant are elected by the Board 
of Directors at the first meeting after each annual 
meeting of the Registrant's shareholders and hold office 
until their death or until they shall resign or have been 
removed from office.

The date of the next annual meeting of the Registrant 
will be determined by the Registrant's Board of Directors 
in accordance with Colorado law.

(b)  Compliance With Section 16(a) of The Exchange Act

No persons or entities holding Registrant's securities or 
serving as Officers or Directors of Registrant are 
subject to the reporting requirements of Section 16(a) of 
The Exchange Act.


ITEM 10.  EXECUTIVE COMPENSATION

Since 1991 the only officer who has received compensation 
for his services is the President and CEO, Keith P. 
Lanneau.  From December 1, 1991 to December 31, 1994 he 

16

<PAGE>

was compensated by an accrual of $5,000 per month.  In 
lieu of cash payment for services, which has not been 
feasible for the Company, Mr. Lanneau accepted 
convertible promissory notes of the Company, payble on 
demand, with 8% interest compounded quarterly.  Said 
notes, in the aggregate amount of $192,943, were 
converted on April 1, 1995 into 80,000 shares of common 
stock of the Company at a price of $2.42 per share.

Commencing January 1, 1995 to the present Helix 
International Corporation and Arrowhead Technology 
Associates, Inc., both affiliates of Registrant, have 
provided full time management consulting services to the 
Company for a fee of $5000 per month through June 30, 
1995 and for $6000 per month thereafter.  These fees 
include Mr. Lanneau's services as President and CEO of 
the Company.

Since inception of the Company no persons have received 
any monetary compensation for their services as Members 
of the Board of Directors.  On November 28, 1995, in 
consideration of their past services as Directors of the 
Company the following persons were granted stock options 
to purchase common stock at a price of $1.00 per share, 
the number of shares being shown beside each name:

Director                                Number of Shares

Thomas L. Frazer	                         5,000
Dr. Robert J. Love                         5,000
Michael K. Marcantel                      10,000
Dr. Donald R. Owen                        10,000
Keith P. Lanneau                          15,000



The above cited options are all exercisable upon issuance 
and expire at various dates through 1998.


SUMMARY ANNUAL COMPENSATION TABLE 

Name and       Year   Salary   Bonus   Other Compensation
Position 
__________     ____   ______   _____    ________________
Keith P. 
    Lanneau    1991  $ 5,000    None           None
Director 12/91
 to 6/92, 
President 
and CEO and    1992  $60,000    None           None
Director from
7/92 to 
Present        1993  $60,000    None           None

               1994  $60,000    None           None

               1995        -    None         Options

               1996        -    None           None

17

<PAGE>

ITEM 11.  SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS 
AND MANAGEMENT

(a)  Present Ownership

The following table sets forth, as of the date of this 
Report, the stock ownership of each person known by the 
Registrant to be the beneficial and/or record owner of 
five percent or more of the Registrant's Common Stock, 
each Officer and Director individually and all Officers 
and Directors of the Registrant as a group:

NAME AND ADDRESS      NUMBER OF SHARES          PERCENT
- ----------------      ----------------          -------

Helix International 
Corporation                540,000  (1)           42.4% 
2151 East Lakeshore Drive
Baton Rouge, LA 70808

Joy G. Lanneau              91,000  (2)            7.1%
2151 East Lakeshore Drive
Baton Rouge, LA 70808

Keith P. Lanneau           631,000  (3)           49.6%
2151 East Lakeshore Drive
Baton Rouge, LA 70808

Thomas L. Frazer           131,776  (4)           10.3%
7520 Perkins Rd. Suite 280
Baton Rouge, LA 70808

Robert J. Love                 -0-  (5)            0.0%
3483 W. 18th Ave.
Vancouver, B.C.
Canada V6S 1A8

Michael K. Marcantel           -0-  (6)            0.0%
8748 Quarters Lake Road
Baton Rouge, LA 70809

Donald R. Owen              10,000  (7)            0.7%
5701 Crawford St., Suite 1
Harahan, LA 70123

                           -------               ------
All Officers and 
Directors                  772,776                60.8%
As a Group (5 persons)
                           -------               ------  

University Research &       72,075                 5.6%
  Marketing, Inc.
LSU Business & Tech Center
South Stadium Drive
Baton Rouge, LA 70803      =========             ======

TOTAL SHARES OUTSTANDING   1,270,620             100.0%
                           =========             ======

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<PAGE>

(b)  Ownership Assuming Conversion of All Promissory 
Notes and Exercise of Options

NAME AND ADDRESS    NUMBER OF SHARES            PERCENT
- ----------------    ----------------            -------

Helix International 
Corporation                  820,907  (1)         45.9%

Joy G. Lanneau               279,993  (2)         15.6%

Keith P. Lanneau           1,115,900  (3)         62.4%

Thomas L. Frazer             136,776  (4)          7.6%

Robert J. Love                 5,000  (5)          0.2%

Michael K. Marcantel          10,000  (6)          0.5%

Donald R. Owen                20,000  (7)          1.1%
                           ---------             -----
All Officers and Directors 1,287,676              72.1%   
As a Group (5 persons)                          
                           =========             ======
TOTAL SHARES OUTSTANDING   1,785,520             100.0%
                           =========             ======

(c)  Notes to Tables (a) and (b) Above

(1)  The controlling shareholder, Helix International 
Corporation, held, as of December 31, 1996, a promissory 
note of Registrant convertible into 280,907 shares of 
Registrant's common stock.

(2)  Mrs. Lanneau is beneficial owner of 91,000 shares of 
stock and of notes convertible into 188,993 shares of 
stock, either held personally or beneficially as sole 
shareholder of Arrowhead Technology Associates, Inc..

(3)  Mr. Lanneau is beneficial owner as Chief Executive 
Officer of Helix International Corporation, and as spouse 
of Mrs. Lanneau, of 631,000 shares of stock.  As a 
Director he also holds an option to purchase 15,000 
shares.  He is beneficial owner of the stock conversion 
rights held by Helix International and by Mrs. Lanneau.

(4)  Mr. Frazer is the holder of record of 131,776 shares 
of stock and an option, as a Director, to purchase an 
additional 5,000 shares.

(5)  Dr. Love holds, as a Director, an option to acquire 
5,000 shares of stock.

(6)  Mr. Marcantel holds, as a Director, an option to 
purchase from the Company 10,000 shares of stock.

(7)  As controlling shareholder of TPI, Dr. Owen is the 
beneficial owner of 10,000 shares of the Company's stock.  
He also owns, as a Director, an option to purchase an 
additional 10,000 shares. 

19

<PAGE>

ITEM 12.  CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

(a)  With Helix International Corporation

From March 1989 to March 1990, the Company contracted 
with Helix International Corporation ("Helix"), a 
principal shareholder, to conduct research on lytic 
peptides and the Company's proprietary Cytoporin 
compounds on a contract basis for the account of the 
Company.  The Company incurred a total of $655,321 in 
such research costs paid or payable to Helix during this 
period.  These costs included payments by Helix to 
Louisiana State University ("LSU") for contract research 
support and to patent attorneys for development of a 
patent position on the Company's proprietary technology.  
At December 31, 1996, the Company's promissory note for 
$690,944 was outstanding to Helix to recognize the 
balance due to Helix on unpaid research costs, accrued 
interest, consulting fees, and patent pass through costs.  
In addition, $50,000 in debt payable to Helix had been 
converted in September 1993 into common stock equity of 
the Company on the basis of $2.50 per share. 

Commencing January 1, 1995 the Company began to accrue 
for Helix International a management consulting fee of 
$5000 per month, which fee was increased to $6000 per 
month effective July 1, 1995.  This fee arrangement 
includes the services of Mr. Lanneau as President and CEO 
of the Company, and Mr. Lanneau has not otherwise been 
compensated by the Company since 1994 for his services as 
an officer.  This consulting fee arrangement with Helix 
International was terminated June 30, 1996 and was 
transferred to Arrowhead Technology Associates, Inc.

(b) With Arrowhead Technology Associates, Inc.

Arrowhead Technology Associates, Inc. is a business 
consulting company affiliated with Mr. Lanneau.  On July 
1, 1996 the Company began to accrue for Arrowhead a 
consulting fee of $6000 per month, which fee continues to 
the present and includes the services of Mr. Lanneau as 
President and CEO of the Company.  Mr. Lanneau receives 
no other compensation for his services as an officer of 
Registrant.  Office rent and general office expenses of 
the Company are paid by Arrowhead and the Company either 
reimburses Arrowhead or accrues these expenses to the 
Company's promissory note payable to Arrowhead.  This is 
more fully discussed in Item 12. (d) below. 

(c)  With University Research & Marketing, Inc.

In March 1990, when Helix became unable to continue 
funding of the Company's research and other business 
activities, the Company entered into an agreement with 
another shareholder, University Research & Marketing, 
Inc. (URM), as part of a restructuring of debt, to 
continue the Company's research and development for a 
flat fee of $20,000 per month plus patent and other out 
of pocket costs.  Under this agreement, which terminated 
the Company's earlier agreement with Helix, URM provided 
administrative services and sponsored research on behalf 
of the Company totalling $360,000 for the period from 
March 1990 until August 1991.  The $360,000 in debt 
incurred under this agreement was converted into common 
stock equity of the Company by the shareholder in 
September, 1993.  The conversion was on the basis of 
$2.50 per share of stock.  At March 31, 1995, the Company 
remained obligated to URM for out of pocket costs, patent 
costs, and interest in the form of a promissory note in 
the amount of $104,331.  On April 1, 1995 this note was 
also converted into common stock at $2.50 per share.

As part of the LSU Settlement Agreement (described in 
Note 1 to the Financial Statements, page F-10), the 
Company entered into a sublicense agreement with URM, a 
shareholder, for the development and marketing of a 
portion of the Company's proprietary technology, 
specifically the use of the technology in food 
preservation and purification of drinking water.

20

<PAGE>

(d)  With Keith P. Lanneau

The Company maintains it corporate offices in the offices 
of its President, Keith P. Lanneau.  From Inception to 
December 31, 1996, the Company has incurred $128,255 in 
rental and general office expense reimbursements which 
have been paid or are payable to Arrowhead Technology 
Associates, Inc., another company affiliated with Mr. 
Lanneau.  In September, 1993 $50,000 of the debt incurred 
with the affiliated company was converted into common 
stock equity of the Company.  The conversion was on the 
basis of $2.50 per share of stock.  At December 31, 1996, 
the balance of the unpaid debt to the affiliated company, 
Arrowhead Technology Associates, Inc.,  was evidenced by 
the Company's promissory note in the amount of $87,871. 
This balance includes unpaid accruals for rent, general 
office expenses, the consulting fee described in Item 12. 
(b) above, and accrued interest.


ITEM 13.  EXHIBITS AND REPORTS ON FORM 8-K

(a) Exhibits

Exhibit No.        Description and Location
- -----------        ------------------------

3-a             Articles of Incorporation and ByLaws
                Incorporated by reference to Exhibit No.
                3 to the Registrant's Registration
                Statement (No.33-20897-D) dated July 
                1, 1988.

3-b             Amendments to Articles of Incorporation
                Incorporated by reference to Form 10-KSB 
                for 1993 filed by Registrant with the SEC
                (File No. 33-20897-D) on September 30,
                1994.

3-c             Amendments to By Laws
                Incorporated by reference to Form 10-KSB 
                for 1993 filed by Registrant with 
                the SEC (File No. 33-20897-D) on 
                September 30, 1994.

13-a            Registrant's Form 10-Q For the Quarter 
                Ended September 30, 1989
                Incorporated by reference to Form 10-Q
                filed by Registrant with the SEC 
                (File No. 33-20897-D) on November l5, 
                1989.

13-b            Registrant's Form 10-KSB for the Five 
                Years Ended December 31, 1993
                Incorporated by reference to Form 10-KSB 
                for 1993 filed by Registrant with 
                the SEC (File No. 33-20897-D) on 
                September 30, 1994.

13-c            Registrant's Form 10-QSB For the Quarter 
                Ended March 31, 1994 Incorporated by 
                reference to Form 10-QSB (First Quarter, 
                1994) filed by Registrant with the SEC 
                (File No. 33-20897-D) on September 30, 
                1994.

13-d            Registrant's Form 10-QSB For the Quarter 
                Ended June 30, 1994 Incorporated by 
                reference to Form 10-QSB (Second Quarter, 
                1994) filed by Registrant with the SEC
                (File No. 33-20897-D) on September 30, 
                1994.

13-e            Registrant's Form 10-QSB For the Quarter 
                Ended September 30, 1994 Incorporated by 
                reference to Form 10-QSB (Third Quarter, 
                1994) filed by Registrant with the SEC 
                (File No. 33-20897-D) on November 12, 
                1994.

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<PAGE>

13-f            Registrant's Form 10-KSB for the Year 
                Ended December 31, 1994 Incorporated by
                reference to Form 10-KSB for 1994 filed
                by Registrant with the SEC (File No. 33-
                20897-D) on April 12, 1995.

13-g            Registrant's Form 10-QSB for the Quarter 
                Ended March 31, 1995 Incorporated by 
                reference to Form 10-QSB (First Quarter, 
                1995) filed by Registrant with the SEC 
                (File No. 33-20897-D) on May 12, 1995.

13-h            Registrant's Form 10-QSB for the Quarter
                Ended June 30, 1995 Incorporated by
                reference to Form 10-QSB (Second Quarter,
                1995) filed by Registrant with the SEC 
                (File No. 33-20897-D) on August 12, 1995.

13-I            Registrant's Form 10-QSB for the Quarter 
                Ended September 30, 1995 Incorporated by 
                reference to Form 10-QSB (Third Quarter, 
                1995) filed by Registrant with the SEC 
                (File No. 33-20897-D) on November 13, 
                1995.

13-j            Registrant's Form 10-KSB for the Year 
                Ended December 31, 1995 Incorporated by 
                Reference to Form 10-KSB for 1995 filed 
                by Registrant with the SEC (File No. 33-
                20897-D) on April 12, 1996.

13-k            Registrant's Form 10-QSB for the Quarter 
                Ended March 31, 1996 Incorporated by 
                reference to Form 10-QSB (First Quarter, 
                1996) filed by Registrant with the SEC 
                (File No. 33-20897-D) on May 16, 1996.

13-l            Registrant's Form 10-QSB for the Quarter 
                Ended June 30, 1996 Incorporated by 
                reference to Form 10-QSB (Second Quarter, 
                1996) filed by Registrant with the SEC 
                (File No. 33-20897-D) on August 12, 1996.

13-m            Registrant's Form 10-QSB for the Quarter 
                Ended September 30, 1996 Incorporated by 
                reference to Form 10-QSB (Third Quarter, 
                1996)filed by Registrant with the SEC 
                (File No. 33-20897-D) on November 8, 
                1996.

22              Notice of 1993 Annual Shareholders' 
                Meeting and Request to Exchange Stock 
                Certificates Pursuant to 500:1 Reverse 
                Stock Split Incorporated by reference to 
                Form 10-KSB for 1993 filed by Registrant 
                with the SEC (File No. 33-20897-D) on 
                September 30, 1994.


(b) Reports on Form 8-K

No reports on Form 8k were filed during any quarter of 
the fiscal year ending December 31, 1996.

22

<PAGE>

SIGNATURES




Pursuant to the requirements of Section 13 or 15(d) of 
the Securities Exchange Act of 1934, the Registrant has 
duly caused this Report to be signed on its behalf by the 
undersigned, thereunto duly authorized.

Registrant:  HELIX BIOMEDIX, INC.  


By:/s/ Keith P. Lanneau
   ____________________________      Date:  April 9, 1997 
   Keith P. Lanneau, President

Pursuant to the requirements of the Securities Exchange 
Act of 1934, this Report has been signed below by the 
following persons on behalf of the Registrant and in the 
capacities and on the dates indicated.


By:/s/ Keith P. Lanneau
   ______________________________    Date:  April 9, 1997 
   Keith P. Lanneau, President, Principal
    Financial Officer, and Director

By:/s/ Michael K. Marcantel
   ______________________________    Date:  April 9, 1997 
   Michael K. Marcantel, Vice President,
    Secretary-Treasurer, and Director

By:/s/ Donald R. Owen
   ______________________________    Date:  April 9, 1997 
   Donald R. Owen, Vice President, Chief
    Scientist, and Director

<PAGE>

HELIX BIOMEDIX, INC.
Financial Statements
December 31, 1995

<PAGE>


CONTENTS



                                                Page   

REPORT OF CERTIFIED PUBLIC ACCOUNTANT           F-1

BALANCE SHEET                                   F-2

STATEMENTS OF OPERATIONS                        F-3

STATEMENT OF STOCKHOLDERS' DEFICIT        F-4 to F-6

STATEMENTS OF CASH FLOWS                  F-7 to F-8

NOTES TO FINANCIAL STATEMENTS             F-9 to F-13

<PAGE>


REPORT OF CERTIFIED PUBLIC ACCOUNTANT




The Board of Directors
Helix Biomedix, Inc.
Baton Rouge, Louisiana


We have audited the accompanying balance sheet of Helix 
Biomedix, Inc. as of December 31, 1996, and the related 
statements of operations, cash flows, and changes in 
stockholders' deficit for each of the two years then 
ended and for the period from inception (November 7, 
1988) to December 31, 1996.  These financial statements 
are the responsibility of the Company's management.  Our 
responsibility is to express an opinion on these 
financial statements based on our audit.

We conducted our audit in accordance with generally 
accepted auditing standards.  Those standards require 
that we plan and perform the audit to obtain reasonable 
assurance that the financial statements are free of 
material misstatement.  An audit includes examining, on a 
test basis, evidence supporting the amounts and 
disclosures in the financial statements.  An audit also 
includes assessing the accounting principles used and 
significant estimates made by management, as well as 
evaluating the overall financial statement presentation.  
We believe that our audit provides a reasonable basis for 
our opinion.

In our opinion, the financial statements referred to 
above present fairly, in all material respects, the 
financial position of Helix Biomedix, Inc. as of December 
31, 1996, and the results of its operations, cash flows, 
and changes in its stockholders' deficit for each of the 
two years ended December 31, 1996, and for the period 
from inception (November 7, 1988) to December 31, 1996 in 
conformity with generally accepted accounting principles.

The accompanying financial statements have been prepared 
assuming the Company will continue as a going concern.  
The company, which is in the development stage, has 
incurred substantial losses since its inception, and has 
minimal current assets with which to repay obligations as 
they come due.  Management plans to raise money in equity 
markets to finance further patent prosecution and ongoing 
research and development activities.  However, there is 
no assurance that management will be successful in 
obtaining additional financing.  These conditions give 
rise to substantial doubt about the Company's ability to 
continue as a going concern.  These financial statements 
do not include any adjustments which may be necessary if 
the Company is unable to continue in existence.


Aurora, Colorado
April 2, 1997


COMISKEY & COMPANY
PROFESSIONAL CORPORATION


F-1

<PAGE>

        HELIX BIOMEDIX INC.
           BALANCE SHEET
         DECEMBER 31, 1996

CURRENT ASSETS
  Cash                                     $      1,369
  Note Receivable - TPI                          25,000
                                              ---------
    Total current assets                         26,369

OTHER ASSETS
  Antimicrobial technology (net)                143,748
  Patents pending and approved (net)            318,785
  Due from affiliated company                     1,839
                                              ---------
    Total other assets                          464,372
                                              ---------
  Total assets                             $    490,741
                                              =========

CURRENT LIABILITIES
  Accounts payable - trade                 $      6,794
  Notes payable                                  40,000
  Notes payable on demand - related parties     193,522
  Accrued interest payable                        8,497
                                              ---------
    Total current liabilities                   248,813

LONG TERM LIABILITIES
  Notes payable to shareholders                 690,944
                                              ---------
                                                690,944

  Total liabilities                             939,757

STOCKHOLDERS' DEFICIT
  Common stock, no par value, 2,000,000 
    shares authorized, 1,270,620
    shares issued and outstanding             2,001,580
  Preferred stock, no par value, 400,000
    shares authorized, no shares issued or
    outstanding                                       -
  Additional paid in capital                    137,400
  Deficit accumulated during the 
    development stage                        (2,587,996) 
                                              ---------
  Total stockholders' deficit                  (449,016) 
                                              ---------
  Total liabilities and stockholders' 
    deficit                                $    490,741
                                              =========

The accompanying notes are an integral part of the
financial statements

F-2

<PAGE>

HELIX BIOMEDIX INC.
STATEMENTS OF OPERATIONS
FOR THE PERIOD FROM INCEPTION (NOVEMBER 7, 1988)
TO DECEMBER 31, 1996

<TABLE>
<S>                                    <C>           <C>          <C>
                                       INCEPTION
                                       TO DEC. 31,       DECEMBER 31,
                                       1996            1996         1995
                                       -----------    -------      --------

REVENUE                                $    10,838  $     7,838  $       -

OPERATING EXPENSES
 Research & Development                  1,361,819      133,500          -
 Amortization                               92,172       17,492     13,828
 Accounting & Legal                        104,096        4,284     22,552
 Advertising                                13,488            -        736
 Compensation costs                        137,400            -    137,400
 Consulting fees                           449,708       85,437     66,000
 Office expense                            128,255       26,414     26,263
 Other general & administrative costs       10,447          685      1,182
                                       -----------    ---------    --------
TOTAL OPERATING EXPENSES                 2,297,385      267,812    267,961
                                       -----------    ---------    --------
NET LOSS FROM OPERATIONS                (2,286,547)    (259,974)  (267,961)

OTHER (INCOME) EXPENSE
 Gain on settlement of lawsuit             (48,574)     (48,574)         -
 Interest expense                          350,023       70,152     55,547
                                       -----------    ---------    --------
                                           301,449       21,578     55,547
                                       -----------    ---------    --------
NET LOSS                                (2,587,996)    (281,552)  (323,508) 
                                       ===========    =========    =======


NET LOSS PER SHARE                     $     (2.90)   $   (0.24)   $ (0.32) 
                                       ===========    =========    =======
WEIGHTED AVERAGE SHARES OUTSTANDING        893,508    1,159,644   1,000,698
                                       ===========    =========   ========
</TABLE>



The accompanying notes are an integral part of the
financial statements.

     F-3

<PAGE>

HELIX BIOMEDIX INC.
STATEMENT OF STOCKHOLDERS' DEFICIT
FOR THE PERIOD FROM INCEPTION (NOVEMBER 7, 1988) TO
DECEMBER 31, 1996


<TABLE>
<S>                     <C>       <C>       <C>        <C>          <C>
                                            ADDITIONAL
                        COMMON STOCK        PAID IN    ACCUMULATED  STOCKHOLDERS'
                        # SHARES  AMOUNT    CAPITAL    DEFICIT      DEFICIT
                        --------- --------- ---------- -----------  -------------
Initial capitalization  1,000,000 $  66,486                            $   66,486
November 7, 1988

Restated for recapitalization
of the private company   (370,000)                                              -

Net loss for the period
ended Dec 31, 1988                                       (217,271)      (217,271)
                        ---------  -------  ---------- -----------  -------------
Balance, 
December 31, 1988         630,000   66,486                (217,271)      (150,785)

Reverse acquisition of
Helix BioMedix, Inc. by
Cartel Acquisitions, Inc.
March 20, 1989            151,262  855,292                                855,292

Net loss for the year
ended Dec 31, 1989                                        (705,641)      (705,641) 
                        ---------  -------  ---------- -----------  -------------
Balance, 
December 31, 1989         781,262  921,778                (922,912)        (1,134)

Net loss for the year
ended Dec 31, 1990                                        (267,541)      (267,541) 
                        ---------  -------  ---------- -----------  -------------
Balance 
December 31, 1990         781,262  921,778              (1,190,453)      (268,675)

Net loss for the year
ended Dec 31, 1991                                        (206,878)      (206,878) 
                        ---------  -------  ---------- -----------  -------------
Balance 
December 31, 1991         781,262  921,778              (1,397,331)      (475,553)

Issuance of stock for
services rendered, 
Dec. 1992, $2.50/share      5,600   14,000                                 14,000

Net loss for the year
ended Dec 31, 1992                                        (191,053)      (191,053) 
                        ---------  -------  ---------- -----------  -------------
Balance 
December 31, 1992         786,862  935,778              (1,588,384)      (652,606)


The accompanying notes are an integral part of the financial statements.

     F-4

<PAGE>

HELIX BIOMEDIX INC.
STATEMENT OF STOCKHOLDERS' DEFICIT
FOR THE PERIOD FROM INCEPTION (NOVEMBER 7, 1988) TO DECEMBER 31, 1995
continued


                                            ADDITIONAL
                        COMMON STOCK        PAID IN    ACCUMULATED  STOCKHOLDERS'
                        # SHARES  AMOUNT    CAPITAL    DEFICIT      DEFICIT
                        --------- --------- ---------- -----------  -------------

Issuance of stock for
services rendered, 
May, 1993 $5.00/share       8,000    40,000                                40,000

Issuance of stock in 
partial settlement of 
account payable,
May, 1993, $5.00/share      4,000    20,000                                20,000

Issuance of stock for 
debt conversion, September
1993, $2.50 per share     184,000   460,000                               460,000

Issuance of stock for 
current and prior services
rendered, December 1993, 
$2.50 per share             9,490    23,724                                23,724

Fractional shares issued
in connection with 1 for
500 reverse stock split        29                                               -

Net loss for the year
ended Dec 31, 1993                                        (222,049)      (222,049) 
                        --------- --------- ---------- -----------  -------------
Balance 
December 31, 1993         992,381 1,479,502             (1,810,433)      (330,931)

Issuance of stock 
for cash, March and 
December 1994,
$2.50 per share            16,000    40,000                                40,000

Net loss for the year
ended Dec 31, 1994                                        (172,503)      (172,503) 
                        --------- --------- ---------- -----------  -------------
Balance, 
December 31, 1994       1,008,381 1,519,502             (1,982,936)      (463,434)

Issuance of stock 
for debt conversion,
April 1995, $2.50/share    41,732   104,331                               104,331


The accompanying notes are an integral part of the financial statements.
     F-5

<PAGE>

HELIX BIOMEDIX INC.
STATEMENT OF STOCKHOLDERS' DEFICIT
FOR THE PERIOD FROM INCEPTION (NOVEMBER 7, 1988) TO DECEMBER 31, 1995
continued


                                            ADDITIONAL
                        COMMON STOCK        PAID IN    ACCUMULATED  STOCKHOLDERS'
                        # SHARES  AMOUNT    CAPITAL    DEFICIT      DEFICIT
                        --------- --------- ---------- -----------  -------------
Issuance of stock for 
debt conversion, 
April 1995, $2.41/share    80,000   192,943                               192,943

Issuance of stock for
cash, April 19, 1995,
$2.50 per share             4,800    12,000                                12,000

Issuance of stock for
debt conversion, 
September 1995,
$2.50 per share            14,731    36,828                                36,828

Issuance of stock 
consideration in 
cooperative endeavor 
agreement Nov. 10, 1995    10,000    25,000                                25,000

Issuance of stock options                      137,400                    137,400

Net loss for the year
ended Dec 31, 1995                                        (323,508)      (323,508) 
                        --------- --------- ---------- -----------  -------------
Balance 
December 31, 1995       1,159,644 1,890,604    137,400  (2,306,444)      (278,440)

Issuance of stock 
for conversion of debt
and accounts payable 
for consulting fees, 
December 1996.
$1.00 per share           110,976   110,976                               110,976

Net loss for the year
ended Dec 31, 1996                                        (281,552)      (281,552) 
                        --------- --------- ---------- -----------  -------------
Balance 
December 31, 1996       1,270,620 2,001,580    137,400  (2,587,996)      (449,016)
                        ========= ========= ========== ===========  =============
</TABLE>

The accompanying notes are an integral part of the financial statements.

     F-6

<PAGE>

HELIX BIOMEDIX, INC.
STATEMENTS OF CASH FLOWS
FOR THE PERIOD FROM INCEPTION (NOVEMBER 7, 1988) TO DECEMBER 31, 1996

<TABLE>
<S>                                       <C>          <C>         <C>
                                          INCEPTION
                                          TO DEC. 31,     DECEMBER 31,
                                          1996          1996        1995
                                          -----------  ----------  ----------

CASH FLOWS FROM OPERATIONS
Net Loss                                $  (2,587,996) $ (281,552) $ (323,508)
Adjustments to reconcile net loss
 with net cash flows from operations
  Stock for services                          135,161      37,437           -
  Accrued interest receivable                  (1,839)     (1,839)          -
  Amortization                                 92,353      17,492      13,828
  Compensation Cost                           137,400           -     137,400
  Consultation Fees                           151,437      85,437      66,000
  Research & Development                       24,000      24,000           -
  Increase(decrease) in accounts
   payable                                      6,794     (31,581)    (18,451)
  Increase (decrease) in accounts
   payable - related party                  1,034,880           -      70,569
  Increase (decrease) in accrued
   interest payable                             8,497       3,582        (856) 
                                          -----------  ----------  ----------
NET CASH USED IN OPERATIONS                  (999,313)   (147,024)    (55,018)

CASH FLOWS FROM INVESTING ACTIVITIES
Patents                                      (191,695)    (13,689)          -
                                          -----------  ----------  ----------
NET CASH USED IN INVESTING ACTIVITIES        (191,695)   (13,689)           -

CASH FLOWS FROM FINANCING ACTIVITIES
Cash received in Cartel
 reverse acquisition                          634,497           -           -
Due from Affiliate                                  -      30,124           -
Notes Receivable                              (25,000)          -     (25,000)
Notes payable                                  47,394      (4,131)     35,742
Related party notes payable (net)             409,947      59,323      20,500
Issuance of stock for cash                     52,000           -      12,000
Issuance of stock for debt                     73,539      73,539           -
                                          -----------  ----------  ----------
NET CASH PROVIDED BY FINANCING ACTIVITIES   1,192,377     158,855      43,242
                                          -----------  ----------  ----------
NET INCREASE (DECREASE) IN CASH                 1,369      (1,858)    (11,776)

CASH, BEGINNING, OF PERIOD                          -       3,227      15,003
                                          -----------  ----------  ----------
CASH, END OF PERIOD                     $       1,369  $    1,369  $    3,227
                                          ===========  ==========  ==========


The accompanying notes are an integral part of the financial statements

     F-7

<PAGE>

HELIX BIOMEDIX, INC.
STATEMENTS OF CASH FLOWS
FOR THE PERIOD FROM INCEPTION (NOVEMBER 7, 1988) TO DECEMBER 31, 199
continued



SUPPLEMENTAL SCHEDULE OF NON-CASH INVESTING AND FINANCING ACTIVITIES
AND OTHER CASH INFORMATION



                                          INCEPTION
                                          TO DEC. 31,     DECEMBER 31,
                                          1996          1996        1995
                                          -----------  ----------  ---------

Stock issued to acquire patents      $      66,486  $         -  $         -
Debt issued to acquire technology          200,000            -            -
Bridge loans outstanding at acquisition    200,000            -            -
Patent costs included in accts payable      74,120        1,784       25,874
Accounts payable converted to notes        687,264       37,437            -
Accrued interest rolled into note          271,169       69,501       56,410
Notes converted to equity                  867,023       72,921      334,102

Cash paid for interest and taxes               651          651            -
</TABLE>

The accompanying notes are an integral part of the financial statements

F-8

<PAGE>

Helix BioMedix, Inc.
Notes to Financial Statements
For the period from inception (November 7, 1998) to December 31, 1996


1.Summary of Significant Accounting Policies
Description of entity
Helix BioMedix, Inc., formerly Cartel Acquisitions, Inc. ("the Company") was 
formed laws of the state of Colorado on February 2, 1988 to create a corporate
vehicle acquire a business opportunity.  On March 20, 1989, the Company 
acquired 100% of outstanding shares of Helix BioMedix, Inc., a Louisiana 
corporation, ("BioMedix Louisiana") in exchange for 630,000 shares of the 
Company's common stock.  The C acquired its shares from Helix International 
Corporation.  BioMedix of Louisiana incorporated on November 7, 1988 as a 
separate corporate entity from Helix Inter Inc., to develop therapeutic 
biopharmaceuticals for animal and human health care accompanying financial 
statements present the financial position and results of BioMedix of Louisiana 
since inception.

Unless otherwise noted, all references herein to ("the Company") refer to Helix
Inc., the Colorado corporation, and its wholly owned subsidiary, Helix BioMedix,
Louisiana.

Development stage activities
The Company has been involved in the business of conducting research both intern
in conjunction with a research and development arrangement with a Louisiana 
State University (LSU), in the field of biotechnology.  The Company applies 
genetic engineering techniques to the development of potential commercial 
products primarily in the human therapeutics and agribusiness.

In conjunction with the incorporation of BioMedix of Louisiana, Helix 
transferred an Assignment of Interest in Technology, all of Helix's right, title
and interest technology and potential patent rights relating to the use of lytic
peptides in human health care.  Furthermore, Helix granted to BioMedix of 
Louisiana all of Helix's rights and obligations associated with the Helix/LSU 
Antimicrobial Project relating to peptides in animal and human health care.  In
exchange for the transfer of technology, BioMedix of Louisiana issued 100% of 
its stock to Helix and signed a $200,000 promissory note to Helix.

Concurrently with the aforementioned events, the Company entered into an 
agreement Helix International with provided that the scientific employees of 
Helix continue lytic peptide research on a contract basis for the account of the
Company.  Under of the Agreement, Helix provided research associates, 
laboratory and office facilities and all administrative services to the Company
on a cost plus 15% basis until an aggregate of $500,000 in expenditures had been
reached.  This arrangement continued through February 1990.

In March 1990, the Company' in-house research and development activities were 
curtailed pending additional financing.  Concurrently, the Company underwent a 
de-facto change in control wherein Helix International sold the majority of its
controlling stock interest in the Company to University Research Marketing, Inc.
("URM").  Concurrently with this action, the Company entered into an agreement 
with URM to provide administrative services and to continue its research and 
development for a flat fee of $20,000 per month plus patent and other out of 
pocket costs.  URM performed such services and funded research at LSU on behalf
of the Company from March 1990 until August 1991.

     F-9

<PAGE>

Helix BioMedix, Inc.
Notes to Financial Statements
For the period from inception (November 7, 1998) to December 31, 1996
continued

In July 1992, de-facto control of the Company was returned to Helix 
International, and the Company, with the assistance of both URM and Helix 
International, began a series of negotiations with LSU which culminated in the
February 1993 Agreement of Settlement Compromise and Release.  This settlement
agreement essentially released LSU, the Company, Helix International, URM, and
Helix Phytonetix, a related company, from defaults under their original 
respective agreements.  The settlement renewed the Company's exclusive license
in five lytic peptide patents currently under development.  Excluding research 
and development costs expensed to operations as incurred, the Company's 
investment in these patents was $318,785, net of amortization,  at December 31,
1996 as part of the settlement, the Company executed a sublicense agreement with
URM for the development and marketing of a portion of the patented technology.

In 1993, the Company entered into an agreement with the Louisiana Partnership 
for Technology and Innovation to obtain assistance in the implementation of a 
financial and managerial restructuring plan for the Company, and in the 
development and implementation of licensing programs for the technology.  In 
consideration for these services, the Company issued 8,000 shares of its common
stock to the Partnership in May 1993.

In late 1993, the Company entered into negotiations with Therapeutic Peptides, 
Inc. (TPI), the objective of which is to bring about a merger of TPI into Helix
BioMedix, Inc., contingent upon the successful completion of the Company's 
financing plan.  Since 1993 and through the present, TPI has continued to 
conduct lytic peptide research on behalf of the Company.

In November 1995, the Company, in lieu of a proposed merger with TPI, entered 
into a cooperative endeavor agreement with Therapeutic Peptides, Inc.  Upon 
consummation of the agreement, Therapeutic Peptides, Inc. received 10,000 
shares of stock in Helix BioMedix, Inc., and shall henceforth share in the 
royalties received by Helix BioMedix, Inc. with respect to the derivative 
peptides.  The  Company continues to fund research on its peptides at the 
laboratories of TPI.

During 1996, the Company settled a pending lawsuit, more fully described in 
Note 6.

Due to the fact that the Company's research and development activities have 
begun but there has been no significant revenue therefrom, the Company is in 
the development stage as defined in Statement of Financial Accounting Standards
 #7. 

The following are the Company's significant accounting policies:

Basis of Presentation
The accompanying financial statements have been prepared assuming the Company 
will continue as a going concern.  The Company, which is in the development 
stage, has incurred substantial losses since its inception, and has no current 
assets with which to repay obligations as the come due.  Management plans to 
raise money in equity markets to finance further patent prosecution and ongoing
research and development activities.  However, there is no assurance that 
management will be successful in obtaining additional financing.  These 
conditions give rise to substantial doubt about the Company's ability to 
continue as a going concern.  These financial statements do not include any 
adjustments which may be necessary if the Company is unable to continue.

     F-10

<PAGE>

Helix BioMedix, Inc.
Notes to Financial Statements
For the period from inception (November 7, 1998) to December 31, 1996
continued

Intangibles
Patent costs, consisting primarily of legal and filing fees, are capitalized.  
Amortization is taken on the straight line method over the life of each patent 
commencing upon the issuance of the patent(s), not to exceed 17 or 20 years, 
depending on the date the patent was issued, or the date the application was 
filed.  Antimicrobial technology which was purchased in conjunction with the 
patents, has been capitalized at the basis of the debt issued for it.  This 
technology is being amortized ratably over twenty years.  Organization costs 
were amortized ratably over 60 months.

Research and Development
Research and development costs are expensed as incurred.

Statement of cash flows
For purposes of the statement of cash flows, the company considers all highly 
liquid debt instruments purchased with an original maturity of three months or 
less to be cash equivalents.

Loss per share
Loss per share has been computed using the weighted average number of shares 
outstanding during the period.  Filly diluted earnings per share have not been 
presented as their effect is estimated to be antidilutive.

Income taxes
For all periods presented, the Company has computed its income tax benefit under
FASB 109 - Accounting for Income Taxes.  Because of the company's creation of a
valuation allowance for the tax benefit of net operating loss carryforwards and
R & D credit carryforwards, there is no material difference in the financial 
statements between income tax calculated under FASB 109 and income tax 
calculated under APB 11.

Reverse stock split
On December 29, 1993 the company underwent a 1 for 500 reverse stock split.  
All share and per share amounts have been retroactively restated to reflect 
the split.

2.Notes Payable
The Company is obligated under the following notes at December 31, 1996


8% convertible demand note
payable to shareholder, principal
and interest originally payable in
March 1990, extended until August
1991, now due September 1998.       $  690,944

8% convertible demand note,
interest due quarterly.                  4,529

8% convertible promissory note,
principal and interest due June 1996.    4,000

12% promissory note, principal and
interest due November 1989               2,000

     F-11

<PAGE>

Helix BioMedix, Inc.
Notes to Financial Statements
For the period from inception (November 7, 1998) to December 31, 1996
continued


Two 8% convertible demand
notes payable to shareholder, due
on demand.                             188,993

Three 12% promissory notes due
December 1997, each note
convertible into 400 shares of
common stock at the option of the
holder.                                  9,000

10.25% promissory note, principal
and interest due May 1996               25,000
                                       -------

Total notes outstanding                924,466
Less amount classified as current      233,522
                                       -------
                                    $  690,944
                                       =======

The shareholder note for $690,944 is secured by a first security 
interest in technology and intellectual property rights of the 
Company.  Interest is payable quarterly in cash or common shares of 
the Company at the rate of $2.50 per share, or may be converted to 
principal.  Form of  payment of quarterly interest is at the 
discretion of the note holder.  The note plus arrcued interest is 
convertible in whole or in part at any time prior to maturity into 
shares of the Company's common stock.  Stock conversion Stock 
conversion will be made at $2.50 per share.

The shareholder notes for $188,993 are secured by a first security 
interest in technology and intellectual property rights of the 
Company.  Interest is payable quarterly in cash or common shares of 
the Company at the rate of $1.00 per share, or may be converted to 
principal.  Form of payment of quarterly interest is at the 
discretion of the note holder.  The note plus accrued interest is 
convertible in whole or in part at any time prior to maturity into 
shares of the Company's common stock at $1.00 per share.

The 8% note for $4,000 is convertible into shares of the Company's 
common stock at $2.50 per share.

Debt maturities over the next five years are as follows:  due in 
1997, $233,522; due in 1998, $690,944; and, due thereafter $0.

3.Stockholders' Equity
The Company has 1,270,620 outstanding common shares and no 
outstanding preferred shares.  The Company is authorized to issue 
2,000,000 common and 400,000 preferred shares.  The Company's 
president, Keith P. Lanneau, holds a total of 631,000 shares 
beneficially as shareholder in Helix International, which holds 
540,000 of the Company's shares, and as beneficial owner of Arrowhead 
Technology Associates, which holds 11,000 of the Company's shares and 
an additional 80,000 shares from the conversion of debt owed.

On December 29, 1993, the Company underwent a 1 for 500 reverse stock 
split.  All share and per share amounts in these financial statements 
have been retroactively restated to reflect this reverse split.

     F-12

<PAGE>

Helix BioMedix, Inc.
Notes to Financial Statements
For the period from inception (November 7, 1998) to December 31, 1996
continued

At December 31, 1996, the Company had outstanding stock options to 
purchase 45,600 shares of the Company's common stock, 600 of which 
state an exercise price of $0.50 per share and the remaining 45,000 
at a price of $1.00 per share.  The options became exercisable upon 
issuance and expire at various dates through 1998.  During 1996, 
45,800 stock options were canceled upon the conversion of debt to 
equity. 

4.Income Taxes
At December 31, 1996 the Company has approximately $2,588,000 in net 
operating loss carryforwards and approximately $91,404 in Research 
and Development tax credit carryforwards available to offset future 
taxable income and related income tax.  The operating loss 
carryforwards expire between 2003 and 2011.  The tax benefit of these 
carryforwards has been offset by a full allowance for realization.

5.Related Party Transactions
From March 1989 to March 1990, the Company contracted with Helix 
International, Inc., a principal shareholder, to conduct lytic 
peptide research on a contract basis for the account of the Company.  
The Company incurred a total of $655,321 in research costs paid or 
payable to Helix International during this period.  At December 31, 
1996. a promissory note for $690,944 was outstanding, consisting of 
unpaid research costs, accrued interest, consulting fees, and patent 
pass through costs.  In addition, $50,000 in debt payable t Helix 
International had been converted to equity in 1992.

The Company maintains its corporate offices in the offices of its 
president.  From inception to December 31, 1996, the Company has 
incurred $128,255 in rental and general office expense reimbursements 
which have been paid or are payable to an affiliated company.

The President of the Company is also a principal shareholder of Helix 
Phytonetix, Inc. ("Phytonetix").  Phytonetix is a party to the LSU 
settlement agreement described in Note 1.  Due to the out of court 
settlement more fully described in Note 6, Phytonetix  paid the 
$30,124 to the Company, which was outstanding at December 31, 1995.

As part of the LSU settlement described in Note 1, the Company 
entered into a sublicense agreement with URM, a shareholder, for the 
development and marketing of a portion of the patented technology, 
specifically the use of the technology in food preservation and 
purification of drinking water.

For the year ended December 31, 1996, $36,000 of consulting fees have 
accrued to each of Helix International, Inc., and Arrowhead 
Technology Associates, Inc.

The note receivable from Therapeutic Peptides, Inc.(TPI), a 
shareholder of the Company, was due June 30, 1996.  the Company plans 
to write off this receivable against invoices received from TPI for 
work to be performed in future periods on behalf of the Company in 
the area of research & development.  For the year ended December 31, 
1996 the Company paid $99,500 to TPI for these services.

6.Litigation settlement
In 1996, the Company agreed to an out of court settlement resulting 
from a suit filed by the Company and three other parties, including 
Helix International, Inc., University Research and Marketing, Inc. 
and Helix Phytonetix, against former patent attorneys for the failure 
to renew patents held by the  plaintiffs.  The settlement resulted in 
a gain for the Company of $48,574.

     F-13

<PAGE>


<TABLE> <S> <C>

<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM THE 
BALANCE SHEET AND STATEMENTS OF LOSS AND ACCUMULATED DEFICIT AND IS 
QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH 10KSB FOR THE YEAR 
ENDED DECEMBER 31, 1996.
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<FISCAL-YEAR-END>                          DEC-31-1996
<PERIOD-END>                               DEC-31-1996
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<SECURITIES>                                         0
<RECEIVABLES>                                    25000
<ALLOWANCES>                                         0
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                                0
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