HELIX BIOMEDIX INC
NT 10-K, 2000-03-30
BLANK CHECKS
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             U.S. SECURITIES AND EXCHANGE COMMISSION
                      WASHINGTON D.C.  20549


                           FORM 12b-25

SEC FILE NUMBER: 33-20897-D

CUSIP NUMBER:

                   NOTIFICATION OF LATE FILING

(CHECK ONE)


        FORM 10-K
   X    FORM 10-KSB
        FORM 11-K
        FORM 20-F
        FORM 10-Q
        FORM 10-QSB
        FORM N-SAR

Nothing in this Form Shall be construed to imply that the Commission has
verified any information contained herein.

If the notification relates to a portion of the filing checked above,
identify the Item(s) to which the notification relates:
_______________________________

=======================================================================
Part I - Registrant Information
=======================================================================

Full Name of Registrant:
Helix BioMedix, Inc.
- -----------------------


Former Name if Applicable:
N/A
- -------------------------


Address of  Principal Executive  Office (street  and number):
210 Baronne Street, Suite 1004
- -------------------------------------------------------------


City, State and Zip Code:
New Orleans, LA 70112
- -------------------------

=======================================================================
Part II - Rules 12b-25 (b) and (c)
=======================================================================

If the subject report could not be filed without unreasonable effort or
expense and the registrant seeks relief pursuant to Rule 12b-25(b), the
following should be completed. (Check Box if appropriate)  _X_

(a)  The reasons described in reasonable detail in Part III of this form
could not be eliminated without unreasonable effort or expense;

(b)  The subject annual report or semi-annual report/portion thereof will
be filed on or before the fifteenth calendar day following the prescribed
due date; or the subject quarterly report/portion thereof will be filed on
or before the fifth calendar day following the prescribed due date; and

(c)  the accountant's statement or other exhibit required by Rule 12b-25(c)
has been attached if applicable

==========================================================================
Part III - Narrative
==========================================================================

State below in reasonable detail the reasons why the Form 10-K, 11-K, 20-F,
10-Q, or N-SAR or portion thereof, could not be filed within the prescribed
time period.

The registrant's 10-KSB cannot be filed without unreasonable effort and
expense to obtain the appropriate approvals and signatures.

=========================================================================
PART IV - OTHER INFORMATION
=========================================================================

(1)  Name and telephone number of person to contact in regard to this
notification

Name:   R. Stephen Beatty
        -----------------
Area code and phone number: (504) 525-5250
                            --------------

(2)  have all other periodic reports required under Section 13 or 15(d) of
the Securities Exchange Act of 1934  or Section 30 of the Investment
Company Act of 1940 during the preceding 12 months (or for such shorter
period that the registrant was required to file such reports) been filed?
If the answer is no, identify report(s).

__x__  yes    _____  no

(3)  Is it anticipated that any significant change in results of operations
from the corresponding period for the last fiscal year will be reflected by
the earnings statements to be included in the subject report or portion
thereof?

_____  yes    __x__  no

If so, attach an explanation of the anticipated change, both narratively and
quantitatively, and, if appropriate, state the reasons why a reasonable
estimate of the results can not be made.

               Helix BioMedix, Inc.
 __________________________________________________
    (NAME OF REGISTRANT AS SPECIFIED IN CHARTER)

has caused this notification to be signed on its behalf by the undersigned
thereunto duly authorized.


DATE    03/30/00
BY /s/ R. Stephen Beatty


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