BIOSITE DIAGNOSTICS INC
SC 13D, 1997-12-19
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
Previous: BOOTS & COOTS INTERNATIONAL WELL CONTROL INC, SC 13D, 1997-12-19
Next: CRYOMEDICAL SCIENCES INC, 8-K, 1997-12-19




	       SECURITIES AND EXCHANGE COMMISSION
		     Washington D.C.  20549
				
			  SCHEDULE 13D
				
				
	   Under the Securities Exchange Act of 1934
				
				
		BIOSITE DIAGNOSTICS INCORPORATED
			(Name of Issuer)
				
				
		 Common Stock, $0.01 par value
		 (Title of Class of Securities)
				
				
			   090945106
			 (CUSIP Number)
				
				
		    H. Vaughan Blaxter, III
		      1900 Grant Building
		 Pittsburgh, Pennsylvania 15219
				
			 (412) 281-2620
	 (Name, address and telephone number of person
       authorized to receive notices and communications)
				
			December 9, 1997
     Date of Event which Requires Filing of this Statement
				

If the filing person has previously filed a statement on Schedule 13G to report 
the acquisition which is the subject of this statement, and is filing this 
statement because of Rule 13d-1(b) (3) or (4), check the following:       [   ]



Check the following box if a fee is being paid with this statement:       [   ]

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person

     C. G. GREFENSTETTE
     I.D. ####-##-####

2    Check the Appropriate Box if Member of a Group     (a)  [ X ]   (b)  [   ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [   ]

6    Citizenship or Place of OrganizationU.S.

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power
     

8    Shared Voting Power
     1,960,555

9.   Sole Dispositive Power
     

10   Shared Dispositive Power
     1,960,555

11   Aggregate Amount Beneficially Owned by Each Reporting Person
     1,960,555

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     15.32

14   Type of Reporting Person
     IN

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person

     THOMAS G. BIGLEY
     I.D. #

2    Check the Appropriate Box if Member of a Group   (a)  [ X ]    (b)  [    ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [   ]
6    Citizenship or Place of Organization
     U.S.

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power
     

8    Shared Voting Power
     20,164

9.   Sole Dispositive Power
     

10   Shared Dispositive Power
     20,164

11   Aggregate Amount Beneficially Owned by Each Reporting Person
     20,164

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     .16%

14   Type of Reporting Person
     IN

<PAGE>


CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person
     THOMAS G. BIGLEY AND C. G. GREFENSTETTE, TRUSTEES UNDER
     AGREEMENT OF TRUST DATED 12/30/76 FOR THE CHILDREN OF
     JULIET LEA HILLMAN SIMONDS         I.D. #25-6193084

2    Check the Appropriate Box if Member of a Group   (a)  [ X ]     (b)  [   ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [   ]

6    Citizenship or Place of Organization
     Pennsylvania

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power
     5,041

8    Shared Voting Power


9    Sole Dispositive Power
     5,041

10   Shared Dispositive Power

11   Aggregate Amount Beneficially Owned by Each Reporting Person
     5,041

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     .04%

14   Type of Reporting Person
     OO

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person
     THOMAS G. BIGLEY AND C. G. GREFENSTETTE, TRUSTEES UNDER
     AGREEMENT OF TRUST DATED 12/30/76 FOR THE CHILDREN OF
     AUDREY HILLMAN FISHER              I.D. #25-6193085

2    Check the Appropriate Box if Member of a Group  (a)  [ X ]      (b)  [   ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [   ]

6    Citizenship or Place of Organization
     Pennsylvania

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power
     5,041

8    Shared Voting Power


9    Sole Dispositive Power
     5,041

10   Shared Dispositive Power


11   Aggregate Amount Beneficially Owned by Each Reporting Person
     5,041

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     .04%

14   Type of Reporting Person
     OO

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person
     THOMAS G. BIGLEY AND C. G. GREFENSTETTE, TRUSTEES UNDER
     AGREEMENT OF TRUST DATED 12/30/76 FOR THE CHILDREN OF
     HENRY LEA HILLMAN, JR              I.D. #25-6193086

2    Check the Appropriate Box if Member of a Group  (a)  [ X ]      (b)  [   ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [  ]

6    Citizenship or Place of Organization
     Pennsylvania

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power
     5,041

8    Shared Voting Power


9    Sole Dispositive Power
     5,041

10   Shared Dispositive Power


11   Aggregate Amount Beneficially Owned by Each Reporting Person
     5,041

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     .04%

14   Type of Reporting Person
     OO

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person
     THOMAS G. BIGLEY AND C. G. GREFENSTETTE, TRUSTEES UNDER
     AGREEMENT OF TRUST DATED 12/30/76 FOR THE CHILDREN OF
     WILLIAM TALBOTT HILLMAN            I.D. #25-6193087

2    Check the Appropriate Box if Member of a Group  (a)  [ X ]      (b)  [  ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [  ]

6    Citizenship or Place of Organization
     Pennsylvania

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power
     5,041

8    Shared Voting Power


9    Sole Dispositive Power
     5,041

10   Shared Dispositive Power


11   Aggregate Amount Beneficially Owned by Each Reporting Person
     5,041

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     .04%

14   Type of Reporting Person
     OO

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person

     HENRY L. HILLMAN
     I.D. ####-##-####

2    Check the Appropriate Box if Member of a Group  (a)  [ X ]      (b)  [  ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [  ]

6    Citizenship or Place of Organization
     U.S.

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power


8    Shared Voting Power
     1,940,391

9    Sole Dispositive Power


10   Shared Dispositive Power
     1,940,391

11   Aggregate Amount Beneficially Owned by Each Reporting Person
     1,940,391

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     15.16%

14   Type of Reporting Person
     IN

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person

     ELSIE HILLIARD HILLMAN
     I.D. ####-##-####

2    Check the Appropriate Box if Member of a Group  (a)  [ X ]      (b)  [  ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [  ]

6    Citizenship or Place of Organization
     U.S.

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power


8    Shared Voting Power
     1,940,391

9    Sole Dispositive Power


10   Shared Dispositive Power
     1,940,391

11   Aggregate Amount Beneficially Owned by Each Reporting Person
     1,940,391

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     15.16%

14   Type of Reporting Person
     IN

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person
     HENRY L. HILLMAN, ELSIE HILLIARD HILLMAN & C. G. GREFENSTETTE,
     TRUSTEES OF THE HENRY L. HILLMAN TRUST U/A DATED NOVEMBER
     18, 1985                                I.D. #18-2145466

2    Check the Appropriate Box if Member of a Group  (a)  [ X ]      (b)  [  ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [  ]

6    Citizenship or Place of Organization
     Pennsylvania

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power
     143,409

8    Shared Voting Power
     1,796,982

9    Sole Dispositive Power
     143,409

10   Shared Dispositive Power
     1,796,982

11   Aggregate Amount Beneficially Owned by Each Reporting Person
     1,940,391

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     15.16%

14   Type of Reporting Person
     OO

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person

     THE HILLMAN COMPANY
     I.D. #25-1011286

2    Check the Appropriate Box if Member of a Group  (a)  [ X ]      (b)  [  ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [  ]

6    Citizenship or Place of Organization
     Pennsylvania

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power


8    Shared Voting Power
     1,796,982

9    Sole Dispositive Power


10   Shared Dispositive Power
     1,796,982

11   Aggregate Amount Beneficially Owned by Each Reporting Person
     1,796,982

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     14.04%

14   Type of Reporting Person
     CO

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person

     WILMINGTON INVESTMENTS, INC.
     I.D. #51-0344688

2    Check the Appropriate Box if Member of a Group  (a)  [ X ]      (b)  [  ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [  ]

6    Citizenship or Place of Organization
     Delaware

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power


8    Shared Voting Power
     1,796,982

9    Sole Dispositive Power


10   Shared Dispositive Power
     1,796,982

11   Aggregate Amount Beneficially Owned by Each Reporting Person
     1,796,982

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     14.04%

14   Type of Reporting Person
     CO

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person

     WILMINGTON SECURITIES, INC.
     I.D. #51-0114700

2    Check the Appropriate Box if Member of a Group  (a)  [ X ]      (b)  [  ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [  ]

6    Citizenship or Place of Organization
     Delaware

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power


8    Shared Voting Power
     1,796,982

9    Sole Dispositive Power


10   Shared Dispositive Power
     1,796,982

11   Aggregate Amount Beneficially Owned by Each Reporting Person
     1,796,982

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     14.04%

14   Type of Reporting Person
     CO

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person

     WILMINGTON INTERSTATE CORPORATION
     I.D. #51-0313966

2    Check the Appropriate Box if Member of a Group  (a)  [ X ]      (b)  [  ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [  ]

6    Citizenship or Place of Organization
     Delaware

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power
     134,423

8    Shared Voting Power
     1,662,559

9    Sole Dispositive Power
     134,423

10   Shared Dispositive Power
     1,662,559

11   Aggregate Amount Beneficially Owned by Each Reporting Person
     1,796,982

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     14.04%

14   Type of Reporting Person
     CO

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person

     HILLMAN/CHESAPEAKE LIMITED PARTNERSHIP
     I.D. #51-0315605

2    Check the Appropriate Box if Member of a Group  (a)  [ X ]      (b)  [  ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [  ]

6    Citizenship or Place of Organization
     Delaware

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power


8    Shared Voting Power
     1,662,559

9    Sole Dispositive Power


10   Shared Dispositive Power
     1,662,559

11   Aggregate Amount Beneficially Owned by Each Reporting Person
     1,662,559

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     13%

14   Type of Reporting Person
     PN

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person

     FREDERICK J. DOTZLER
     I.D. #51-0313966

2    Check the Appropriate Box if Member of a Group  (a)  [ X ]      (b)  [  ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [  ]

6    Citizenship or Place of Organization
     U.S.

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power
     6,000

8    Shared Voting Power
     1,662,559

9    Sole Dispositive Power
     6,000

10   Shared Dispositive Power
     1,662,559

11   Aggregate Amount Beneficially Owned by Each Reporting Person
     1,668,559

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     13.04%

14   Type of Reporting Person
     IN

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person

     JOHN REHER
     I.D. #

2    Check the Appropriate Box if Member of a Group  (a)  [ X ]      (b)  [  ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [  ]

6    Citizenship or Place of Organization
     U.S.

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power


8    Shared Voting Power
     1,662,559

9    Sole Dispositive Power


10   Shared Dispositive Power
     1,662,559

11   Aggregate Amount Beneficially Owned by Each Reporting Person
     1,662,559

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     13%

14   Type of Reporting Person
     IN

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person

     MEDICUS MANAGEMENT PARTNERS
     I.D. #94-3089403

2    Check the Appropriate Box if Member of a Group  (a)  [ X ]      (b)  [  ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [  ]

6    Citizenship or Place of Organization
     California

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power


8    Shared Voting Power
     1,662,559

9    Sole Dispositive Power


10   Shared Dispositive Power
     1,662,559

11   Aggregate Amount Beneficially Owned by Each Reporting Person
     1,662,559

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     13%

14   Type of Reporting Person
     PN

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person

     MEDICUS VENTURE PARTNERS 1992, A CALIFORNIA LIMITED
     PARTNERSHIP                        I.D. #94-3154913

2    Check the Appropriate Box if Member of a Group  (a)  [ X ]      (b)  [  ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [  ]

6    Citizenship or Place of Organization
     California

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power
     104,167

8    Shared Voting Power


9    Sole Dispositive Power
     104,167

10   Shared Dispositive Power


11   Aggregate Amount Beneficially Owned by Each Reporting Person
     104,167

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     .81%

14   Type of Reporting Person
     PN

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person

     MEDICUS VENTURE PARTNERS 1991, A CALIFORNIA LIMITED
     PARTNERSHIP                        I.D. #94-3130685

2    Check the Appropriate Box if Member of a Group  (a)  [ X ]     (b)  [  ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [  ]

6    Citizenship or Place of Organization
     California

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power
     333,334

8    Shared Voting Power


9    Sole Dispositive Power
     333,334

10   Shared Dispositive Power


11   Aggregate Amount Beneficially Owned by Each Reporting Person
     333,334

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     2.60%

14   Type of Reporting Person
     PN

<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person

     MEDICUS VENTURE PARTNERS 1990, A CALIFORNIA LIMITED
     PARTNERSHIP                        I.D. #94-3109737

2    Check the Appropriate Box if Member of a Group  (a)  [ X ]      (b)  [  ]

3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to 
     Items 2(d) or 2(e)                                                   [  ]

6    Citizenship or Place of Organization
     California

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power
     520,833

8    Shared Voting Power


9    Sole Dispositive Power
     520,833

10   Shared Dispositive Power


11   Aggregate Amount Beneficially Owned by Each Reporting Person
     520,8333

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     4.07%

14   Type of Reporting Person
     PN
<PAGE>

CUSIP NO. 090945106

1    Name of Reporting Person S.S. or I.R.S. Identification No. of above Person

     MEDICUS VENTURE PARTNERS 1989, A CALIFORNIA LIMITED
     PARTNERSHIP                        I.D. #94-3089404

2    Check the Appropriate Box if Member of a Group  (a)  [ X ]      (b)  [  ]


3    SEC Use Only

4    Source of Funds
     OO

5    Check if Disclosure of Legal Proceedings is Required Pursuant to
     Items 2(d) or 2(e)						       [     ]

6    Citizenship or Place of Organization
     California

Number of Shares Beneficially Owned by Each Reporting Person With

7    Sole Voting Power
     704,225

8    Shared Voting Power


9    Sole Dispositive Power
     704,225

10   Shared Dispositive Power


11   Aggregate Amount Beneficially Owned by Each Reporting Person
     704,225

12   Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares

13   Percent of Class Represented by Amount in Row (11)
     5.50%

14   Type of Reporting Person
     PN

<PAGE>

			  SCHEDULE 13D


	This statement ("Statement") constitutes the Schedule 13D filed with 
the Securities and Exchange Commission (the "Commission") on December 19, 1997 
(the "Filing").

Item 1.   Security and Issuer

	This Statement relates to the Common Stock, $0.01 par value, of 
Biosite Diagnostics Incorporated, a Delaware corporation (the "Issuer").  
The address of the principal executive offices of the Issuer is 11030 Roselle 
Street, San Diego, California 92121.  The Common Stock is quoted on the Nasdaq 
National Market under the symbol "BSTE".

Item 2.   Identity and Background

	(a)  Names of persons filing (individually, the "Registrant" and 
	collectively, the ("Registrants"):

	  Medicus Venture Partners 1992, a California Limited Partnership
	  whose general partners are Hillman/Chesapeake Limited
	  Partnership and Medicus Management Partners.

	  Medicus Venture Partners 1991, a California Limited Partnership
	  whose general partners are Hillman/Chesapeake Limited
	  Partnership and Medicus Management Partners.

	  Medicus Venture Partners 1990, a California Limited Partnership
	  whose general partners are Hillman/Chesapeake Limited
	  Partnership and Medicus Management Partners.

	  Medicus Venture Partners 1989, a California Limited Partnership
	  whose general partners are Hillman/Chesapeake Limited
	  Partnership and Medicus Management Partners.

	  Hillman/Chesapeake Limited Partnership, a Delaware limited
	  partnership whose general partner is Wilmington Interstate
	  Corporation.

	  Medicus Management Partners, a California general partnership
	  whose general partners are Frederick J. Dotzler and John Reher.
	  
	  Wilmington Interstate Corporation, a wholly-owned subsidiary of
	  Wilmington Securities, Inc.

	  Wilmington Securities, Inc., a wholly-owned subsidiary of
	  Wilmington Investments, Inc.

	  Wilmington Investments, Inc., a wholly-owned subsidiary of
	  The Hillman Company.

	  The Hillman Company, a corporation controlled by Henry L.
	  Hillman, Elsie Hilliard Hillman and C. G. Grefenstette,
	  as Trustees of the Henry L. Hillman Trust U/A dated
	  November 18, 1985.

	  Henry L. Hillman, Elsie Hilliard Hillman and C. G.
	  Grefenstette, Trustees of the Henry L. Hillman Trust U/A
	  dated November 18, 1985 (the "1985 Trust").

	  Thomas G. Bigley and C. G. Grefenstette, Trustees Under
	  Agreement of Trust dated 12/30/76 for the Children of
	  Juliet Lea Hillman Simonds (the "1976 JLHS Trust").

	  Thomas G. Bigley and C. G. Grefenstette, Trustees Under
	  Agreement of Trust dated 12/30/76 for the Children of
	  Audrey Hillman Fisher (the "1976 AHF Trust").

	  Thomas G. Bigley and C. G. Grefenstette, Trustees Under
	  Agreement of Trust dated 12/30/76 for the Children of
	  Henry Lea Hillman, Jr. (the "1976 HLH Trust")

	  Thomas G. Bigley and C. G. Grefenstette, Trustees Under
	  Agreement of Trust dated 12/30/76 for the Children of
	  William Talbott Hillman (the "1976 WTH Trust").

	  C. G. Grefenstette

	  Thomas G. Bigley

	  Henry L. Hillman

	  Elsie Hilliard Hillman

	  Frederick J. Dotzler

	  John Reher

	  The name, position, business address and citizenship of each director 
	  and executive officer of the entities listed above, each controlling 
	  person of such entities and each director and executive officer of 
	  any person or corporation in control of said entities, is attached 
	  hereto as Exhibit 1.

     (b)  Business Address

	  The addresses of the Registrants are as follows:

	  The Hillman Company, the 1985 Trust , the 1976 JLHS Trust,
	  the 1976 AHF Trust, the 1976 HLH Trust, the 1976 WTH Trust
	  are each located at:
	  1900 Grant Building
	  Pittsburgh, Pennsylvania 15219

	  Wilmington Interstate Corporation, Wilmington Securities, Inc.,
	  Wilmington Investments, Inc. and Hillman/Chesapeake Limited
	  Partnership are located at:
	  824 Market Street, Suite 900
	  Wilmington, Delaware 19801

	  Medicus Venture Partners 1992, A California Limited Partnership,
	  Medicus Venture Partners 1991, a California Limited Partnership,
	  Medicus Venture Partners 1990, a California Limited Partnership,
	  Medicus Venture Partners 1989, a California Limited Partnership
	  are located at:
	  2180 Sand Hill Road
	  Suite 400
	  Menlo Park, California 94025

	  C. G. Grefenstette
	  2000 Grant Building
	  Pittsburgh, Pennsylvania 15219

	  Thoms G. Bigley
	  One Oxford Centre, 28th Floor
	  Pittsburgh, Pennsylvania 15219

	  Henry L. Hillman
	  2000 Grant Building
	  Pittsburgh, Pennsylvania 15219

	  Elsie Hilliard Hillman
	  2000 Grant Building
	  Pittsburgh, Pennsylvania 15219

	  Frederick J. Dotzler
	  2180 Sand Hill Road
	  Suite 400
	  Menlo Park, California 94025

	  John Reher
	  2180 Sand Hill Road
	  Suite 400
	  Menlo Park, California 94025

     (c)  Principal occupation or employment

	  The principal occupations of the limited partnerships listed in 
	  response to Item 2(a) are:  investments in medical area.

	  The principal occupations of the corporations, listed in response to 
	  Item 2(a) are: diversified investments and operations.

	  The principal occupation of the 1985 Trust is:  diversified 
	  investments and operations.

	  The principal occupation of the 1976 JLHS Trust is:  diversified 
	  investments and operations.

	  The principal occupation of the 1976 AHF Trust is:  diversified 
	  investments and operations.

	  The principal occupation of the 1976 HLH Trust is:  diversified 
	  investments and operations.

	  The principal occupation of the 1976 WTH Trust is:  diversified 
	  investments and operations.

	  Frederick J. Dotzler
	  General Partner, Medicus Management Partners

	  John Reher
	  General Partner, Medicus Management Partners

	  C. G. Grefenstette
	  See Exhibit 1

	  Henry L. Hillman
	  See Exhibit 1

	  Elsie Hilliard Hillman
	  See Exhibit 1

     (d)  Criminal convictions

	  None of the persons named in Item 2(a)(including Exhibit 1) have 
	  been convicted in a criminal proceeding in the last five years.

     (e)  Civil proceedings

	  None of the persons listed in response to Item 2(a) (including 
	  Exhibit 1) have in the last five years been subject to a judgment, 
	  decree or final order as described in Item 2, subsection (e) of 
	  Schedule 13D.

     (f)  Citizenship

	  The 1985 Trust, the 1976 JLHS Trust, the 1976 AHF Trust, the 1976 
	  HLH Trust, the 1976 WTH Trust are Pennsylvania trusts.

	  Medicus Venture Partners 1992, A California Limited Partnership,
	  Medicus Venture Partners 1991, a California Limited Partnership,
	  Medicus Venture Partners 1990, a California Limited Partnership,
	  Medicus Venture Partners 1989, a California Limited Partnership are
	  California limited partnerships.

	  Wilmington Securities, Inc. and Wilmington Investments, Inc. are 
	  Delaware corporations.

	  The Hillman Company is a Pennsylvania corporation.

	  Hillman/Chesapeake Limited Partnership is a Delaware limited 
	  partnership.


	  C. G. Grefenstette, Henry L. Hillman, Elsie Hilliard Hillman, 
	  Frederick J. Dotzler and John Reher are U.S. citizens.

Item 3.   Source and Amount of Funds or Other Consideration

	  None.

Item 4.   Purpose of Transaction

	On December 9, 1997, the 1985 Trust purchased 93,000 shares of Common 
Stock of the Issuer in the open market for a price of $8.50 per share.  The 
1985 Trust currently proposes to purchase up to 107,000 shares of Common 
Stock of the Issuer in the open market.  Such purchase however, may be 
discontinued at any time.  On November 25, 1997 Frederick J. Dotzler (i) 
purchased 3,000 shares of Common Stock of the Issuer in the open market for a 
price of $8.125 per share and (ii) 3,000 shares of Common Stock of the Issuer 
in the open market for a price of $8.00 per share.

	Except as set forth above, the Registrants have no present plans or 
proposals which relate to or would result in (a) the acquisition by any 
person of additional securities of the Issuer or the disposition of securities 
of the Issuer, (b) an extraordinary corporate transaction, such as a merger, 
reorganization, or liquidation involving the Issuer or any of its 
subsidiaries, (c) a sale or transfer of a material amount of the assets of the 
Issuer or any of its subsidiaries, (d) any change in the present Board of 
Directors or Management of the Issuer including any plans or proposals to 
change the number or term of Directors or to fill any existing vacancies on 
the Board, (e) any material change in the present capitalization or dividend 
policy of the Issuer, (f) any other material change in the Issuer's business 
or corporate structure, (g) changes in the Issuer's charter, by-laws or 
instruments corresponding thereto or other actions which may impede the 
acquisition of control of the Issuer by any person, (h) causing a class of 
securities of the Issuer to be delisted from a national securities exchange or 
to cease to be authorized to be quoted in an inter-dealer quotation system of 
a registered national securities association, (i) a class of equity securities 
of the Issuer becoming eligible for termination of registration pursuant to 
Section 12(g)(4) of the Act of 1933, or (j) any action similar to those 
enumerated above.

Item 5.     Interest in Securities of the Issuer

  (a)  Beneficial Ownership

       The following is a list of the Issuer's Common Stock of which each 
       Registrant is a direct, beneficial owner.  It includes the number of 
       shares held and the percentage of the class of such shares that are 
       held by such Registrant.

<TABLE>
<CAPTION>

       Name                     Number of Shares    % of Class of Shares

       <S>                 <C>            <C>
       The 1976 JLHS Trust          5,041        .04%

       The 1976 AHF Trust           5,041        .04%

       The 1976 HLH Trust           5,041        .04%

       The 1976 WTH Trust           5,041        .04%

       The 1985 Trust      143,409        1.12%

       Wilmington Interstate         134,423        1.05%
       Corporation

       Medicus Venture Partners 104,167         .81%
       1992, a California Limited
       Partnership

       Medicus Venture Partners 333,334        2.60%
       1991, a California Limited
       Partnership

       Medicus Venture Partners 520,833        4.07%
       1990, a California Limited
       Partnership

       Medicus Venture Partners 704,225        5.50%
       1989, a California Limited
       Partnership

       Frederick J. Dotzler             6,000        .04%

</TABLE>

  (b)  Power to Vote or Dispose of Shares

       Each person listed above in response to Item 5(a) has the sole power to 
       vote and to direct the vote and the sole power to dispose of and direct 
       the disposition of those shares except as follows:

       (i)  Wilmington Interstate Corporation, Wilmington Securities, Inc.,
	    Wilmington Investments, Inc., The Hillman Company, Henry L. 
	    Hillman, as settlor and Trustee of the 1985 Trust, and Elsie 
	    Hilliard Hillman and C. G. Grefenstette, as Trustees of the 1985 
	    Trust, may be deemed to share voting and disposition power 
	    regarding 134,423 shares of Common Stock held beneficially by 
	    Wilmington Interstate Corporation, 104,167 shares of Common Stock 
	    held beneficially by Medicus Venture Partners 1992, a California 
	    Limited Partnership, 333,334 shares of Common Stock held 
	    beneficially by Medicus Venture Partners 1991, a California Limited
	    Partnership, 520,833 shares of Common Stock held beneficially by
	    Medicus Venture Partners 1990, a California Limited Partnership, 
	    704,225 shares of Common Stock held beneficially by Medicus Venture 
	    Partners 1989, a California Limited Partnership, whose general 
	    partners are Hillman/Chesapeake Limited Partnership and Medicus 
	    Management Partners.  Wilmington Interstate Corporation is the 
	    general partner of Hillman/Chesapeake Limited Partnership.

       (ii) As trustees of the 1985 Trust, Henry L. Hillman, Elsie Hilliard 
	    Hillman and C. G. Grefenstette may be deemed to own beneficially 
	    and share voting and disposition power over 1,940,391 shares of 
	    Common Stock.
	    
      (iii) As trustees of the 1976 JLH S Trust, the 1976 AHF Trust, the 1976 
	    HLH Trust and the WTH Trust Thomas G. Bigley and C. G. Grefenstette 
	    may be deemed to own beneficially and share voting and disposition 
	    power over 20,164 shares of Common Stock.

       (iv) Medicus Management Partners, Federick J. Dotzler and John Reher may
	    be deemed to own beneficially and share voting and disposition 
	    power over 1,662,559 shares of Common Stock.

  (c), (d) and (e).  Not applicable.


Item 6.     Contracts, Arrangements, Understandings of Relationships With 
	    Respect to Securities of the Issuer

	After the Issuer's public offering, the holders of 6,870,513 shares of 
Common Stock issued upon the conversion of certain series of the Issuer's 
Preferred Stock (the "Registrable Shares") or their permitted transferees are 
entitled to certain rights with respect to the registration of such shares 
under the Securities Act of 1933, as amended (the "Securities Act").  If the 
Issuer proposes to register any of its securities under the Securities Act, 
either for its own account or for the account of other security holders, 
holders of such Registrable Shares are entitled to notice of such 
registration and are entitled to include their Registrable Shares therein, 
provided, among other conditions, that the underwriters of any such offering 
have the right to limit the number of shares included in such registration.  
Additionally, holders of the 1,458,334 shares of Common Stock issued upon the 
conversion of the Issuer's Series E Preferred Stock are entitled to similar
"piggy back" rights, on no more than two occasions, commencing two years after 
the Effective Date of the Registration Statement.  In addition, commencing 
180 days after the Effective Date, holders of at least 30% of the Registrable 
Shares may require the Issuer to prepare and file a registration statement 
under the Securities Act, at the Issuer's expense, covering at least 30% of
the shares entitled to registration rights and with an offering price (net of 
underwriting discounts and commissions) of more than $7,500,000, and the 
Issuer is required to use its best efforts to effect such registration, 
subject to certain conditions and limitations.  The Issuer is not obligated
to effect more than two of these stockholder-initiated registrations.  
Further, holders of Registrable Shares may require the Company to file 
additional registration statements with the Securities and Exchange 
Commission on Form S-3, subject to certain conditions and limitations.


Item 7.     Material to be Filed as Exhibits

  Exhibit 1.     Information concerning officers and directors of reporting 
		 persons and certain affiliates thereof.


			   SIGNATURES

After reasonable inquiry and to the best of my knowledge and belief, I 
certify that the information set forth in this statement is true, complete
and correct.


		      MEDICUS VENTURE PARTNERS 1992, A
		       CALIFORNIA LIMITED PARTNERSHIP,
		      MEDICUS VENTURE PARTNERS 1991, A
		       CALIFORNIA LIMITED PARTNERSHIP,
		      MEDICUS VENTURE PARTNERS 1990, A
		       CALIFORNIA LIMITED PARTNERSHIP,
		      MEDICUS VENTURE PARTNERS 1989, A
		       CALIFORNIA LIMITED PARTNERSHIP,

		      By Hillman/Chesapeake Limited Partnership,
		      a General Partner
		      By Wilmington Interstate Corporation, Inc., the sole
		      General Partner


		      By     /s/ Andrew H. McQuarrie
		      _________________________________________
			   Andrew H. McQuarrie, Vice President

		      By Medicus Management Partners,
		      a General Partner


		      By     /s/ Frederick J. Dotzler
		      _________________________________________
			   Federick J. Dotzler, General Partner


		      By     /s/ John Reher
		      _________________________________________
			   John Reher, General Partner

  
		      HILLMAN/CHESAPEAKE LIMITED PARTNERSHIP

		      By Wilmington Interstate Corporation,
		      the sole General Partner


		      By     /s/ Andrew H. McQuarrie
		      _________________________________________
			   Andrew H. McQuarrie, Vice President

		      MEDICUS MANAGEMENT PARTNERS


		      By     /s/ Frederick J. Dotzler
		      _________________________________________
			   Frederick J. Dotzler, General Partner


		      By     /s/ John Reher
		      _________________________________________
			   John Reher, General Partner

		      WILMINGTON INTERSTATE CORPORATION


		      By     /s/ Andrew H. McQuarrie
		      _________________________________________
			   Andrew H. McQuarrie, Vice President


		      WILMINGTON SECURITIES, INC.


		      By     /s/ Andrew H. McQuarrie
		      _________________________________________
			   Andrew H. McQuarrie, Vice President


		      WILMINGTON INVESTMENTS, INC.


		      By     /s/ Andrew H. McQuarrie
		      _________________________________________
			   Andrew H. McQuarrie, Vice President


		      THE HILLMAN COMPANY


		      By     /s/ Lawrence M. Wagner
		      _________________________________________
			   Lawrence M. Wagner, President


		      HENRY L. HILLMAN, ELSIE HILLIARD HILLMAN
		      & C. G. GREFENSTETTE, TRUSTEES OF THE HENRY
		      L. HILLMAN TRUST U/A DATED NOVEMBER 18,
		      1985

		      By     C. G. Grefenstette
		      _________________________________________
			   C. G. Grefenstette, Trustee

		      THOMAS G. BIGLEY AND C. G. GREFENSTETTE,
		      TRUSTEES UNDER AGREEMENT OF TRUST DATED
		      12/30/76 FOR THE CHILDREN OF JULIET LEA
		      HILLMAN SIMONDS, AUDREY HILLIARD HILLMAN
		      HENRY LEA HILLMAN, JR., AND WILLIAM
		      TALBOTT HILLMAN

		      /s/ Thomas G. Bigley
		      ____________________________________________
		      Thomas G. Bigley, Trustee

		      /s/ C. G. Grefenstette
		      ____________________________________________
		      C. G. Grefenstette, Trustee


		      /s/ C. G. Grefenstette
		      ____________________________________________
		      C. G. Grefenstette

		      /s/ Thomas G. Bigley
		      ____________________________________________
		      Thomas G. Bigley

		      /s/ Henry L. Hillman
		      ____________________________________________
		      Henry L. Hillman

		      /s/ Elsie Hilliard Hillman
		      ____________________________________________
		      Elsie Hilliard Hillman 

		      /s/ Frederick J. Dotzler
		      ____________________________________________
		      Frederick J. Dotzler

		      /s/ John Reher
		      ____________________________________________
		      John Reher



EXHIBIT 1

<TABLE>
<CAPTION>

PRINCIPAL OFFICERS AND DIRECTORS OF
THE HILLMAN COMPANY, ALL OF WHOM ARE U.S. CITIZENS

Name and Address                        Title

<S>                                     <C>
Henry L. Hillman                        Chairman of the Executive
2000 Grant Building                     Committee and Director
Pittsburgh, Pennsylvania 15219

C. G. Grefenstette                      Chairman of the Board and
2000 Grant Building                     Director
Pittsburgh, Pennsylvania 15219

Lawrence M. Wagner                      President, Chief Executive
2000 Grant Building                     Officer and Director
Pittsburgh, Pennsylvania 15219

H. Vaughan Blaxter, III                 Vice President, Secretary,
1900 Grant Building                     General Counsel and Director
Pittsburgh, Pennsylvania 15219

Mark J. Laskow                          Vice President and Director
1900 Grant Building
Pittsburgh, Pennsylvania 15219

Anthony J. Burlando                     Vice President - Risk Management
1900 Grant Building                     
Pittsburgh, Pennsylvania 15219

James R. Philp                          Vice President - Personnel and
2000 Grant Building                     Administration
Pittsburgh, Pennsylvania 15219

Richard M. Johnston                     Vice President - Investments and
2000 Grant Building                     Director
Pittsburgh, Pennsylvania 15219

John W. Hall                            Vice President - Accounting and
1800 Grant Building                     Information Services
Pittsburgh, Pennsylvania 15219

Timothy O. Fisher                       Vice President
1900 Grant Building
Pittsburgh, Pennsylvania 15219

Bruce I. Crocker                        Vice President
1800 Grant Building
Pittsburgh, Pennsylvania 15219

Denis P. McCarthy                       Vice President
1900 Grant Building
Pittsburgh, Pennsylvania 15219

Charles H. Bracken, Jr.                 Treasurer
2000 Grant Building
Pittsburgh, Pennsylvania 15219

D. Richard Roesch                       Assistant Treasurer
1800 Grant Building
Pittsburgh, Pennsylvania 15219 

Michael S. Adamcyk                      Assistant Secretary and
2000 Grant Building                     Assistant Treasurer
Pittsburgh, Pennsylvania 15219 

Mary Black Strong                       Assistant Treasurer
2000 Grant Building
Pittsburgh, Pennsylvania 15219

Carol J. Cusick Riley                   Vice President, Associate General
1900 Grant Building                     Counsel and Assistant Secretary
Pittsburgh, Pennsylvania 15219 

Cornel Conley                           Controller - Corporate
1800 Grant Building
Pittsburgh, Pennsylvania 15219

Mark M. Poljak                          Controller - Taxes
1800 Grant Building
Pittsburgh, Pennsylvania 15219

Elsie H. Hillman                        Director
2000 Grant Building
Pittsburgh, Pennsylvania 15219 

Juliet Hillman Simonds                  Director
2000 Grant Building
Pittsburgh, Pennsylvania 15219


PRINCIPAL OFFICERS AND DIRECTORS OF
WILMINGTON INVESTMENTS, INC., ALL OF WHOM ARE U.S. CITIZENS

Lawrence M. Wagner                      President
2000 Grant Building
Pittsburgh, Pennsylvania 15219

Darlene Clarke                          Vice President, Chief Financial
824 Market Street, Suite 900            Officer, Treasurer and Director
Wilmington, Delaware 19801

Lario M. Marini                         Senior Vice President and Director
Wilmington Trust Center
Wilmington, Delaware 19801 

Andrew H. McQuarrie                     Vice President
824 Market Street, Suite 900
Wilmington, Delaware 19801

Richard H. Brown                        Assistant Vice President and
824 Market Street, Suite 900            Assistant Secretary
Wilmington, Delaware 19801

H. Vaughan Blaxter, III                 Secretary
1900 Grant Building
Pittsburgh, Pennsylvania 15219

Charles H. Bracken, Jr.                 Assistant Secretary and
2000 Grant Building                     Assistant Treasurer
Pittsburgh, Pennsylvania 15219

Jody B. Cosner                          Assistant Secretary
824 Market Street, Suite 900
Wilmington, Delaware 19801

Joan E. Bachner                         Assistant Treasurer
824 Market Street, Suite 900
Wilmington, Delaware 19801

Russell W. Ayres, III                   Director
1900 Grant Building
Pittsburgh, Pennsylvania 15219


PRINCIPAL OFFICERS AND DIRECTORS OF
WILMINGTON SECURITIES, INC., ALL OF WHOM ARE U.S. CITIZENS

Lawrence M. Wagner                      President
2000 Grant Building
Pittsburgh, Pennsylvania 15219

Darlene Clarke                          Vice President, Chief Financial
824 Market Street, Suite 900            Officer, Treasurer and Director
Wilmington, Delaware 19801

Lario M. Marini                         Senior Vice President and Director
Wilmington Trust Center
Wilmington, Delaware 19801

Andrew H. McQuarrie                     Vice President
824 Market Street, Suite 900
Wilmington, Delaware 19801

Richard H. Brown                        Assistant Vice President and
824 Market Street, Suite 900            Assistant Secretary
Wilmington, Delaware 19801 

Marian F. Dietrich                      Secretary
1900 Grant Building
Pittsburgh, Pennsylvania 15219 

Charles H. Bracken, Jr.                 Assistant Secretary and
2000 Grant Building                     Assistant Treasurer
Pittsburgh, Pennsylvania 15219

Jody B. Cosner                          Assistant Secretary
824 Market Street, Suite 900
Wilmington, Delaware 19801

Joan E. Bachner                         Assistant Treasurer
824 Market Street, Suite 900
Wilmington, Delaware 19801

Russell W. Ayres, III                   Director
1900 Grant Building
Pittsburgh, Pennsylvania 15219


PRINCIPAL OFFICERS AND DIRECTORS OF
WILMINGTON INTERSTATE CORPORATION, ALL OF WHOM ARE U.S. CITIZENS

Lawrence M. Wagner                      President
2000 Grant Building
Pittsburgh, Pennsylvania 15219

Darlene Clarke                          Vice President, Chief Financial
824 Market Street, Suite 900            Officer, Treasurer and Director
Wilmington, Delaware 19801

Lario M. Marini                         Senior Vice President and Director
Wilmington Trust Center
Wilmington, Delaware 19801 

Andrew H. McQuarrie                     Vice President
824 Market Street, Suite 900
Wilmington, Delaware 19801

Richard H. Brown                        Assistant Vice President and
824 Market Street, Suite 900            Assistant Secretary
Wilmington, Delaware 19801

H. Vaughan Blaxter, III                 Secretary
1900 Grant Building
Pittsburgh, Pennsylvania 15219

Charles H. Bracken, Jr.                 Assistant Secretary and
2000 Grant Building                     Assistant Treasurer
Pittsburgh, Pennsylvania 15219

Jody B. Cosner                          Assistant Secretary
824 Market Street, Suite 900
Wilmington, Delaware 19801

Joan E. Bachner                         Assistant Treasurer
824 Market Street, Suite 900
Wilmington, Delaware 19801

Russell W. Ayres, III                   Director
1900 Grant Building
Pittsburgh, Pennsylvania 15219


GENERAL PARTNERS OF: MEDICUS VENTURE PARTNERS 1992, A CALIFORNIA
LIMITED PARTNERSHIP, MEDICUS VENTURE PARTNERS 1991, A CALIFORNIA
LIMITED PARTNERSHIP, MEDICUS VENTURE PARTNERS 1990, A CALIFORNIA
LIMITED PARTNERSHIP, MEDICUS VENTURE PARTNERS 1989, A CALIFORNIA
LIMITED PARTNERSHIP, ALL OF WHICH WERE ORGANIZED IN THE U.S.

Hillman/Chesapeake Limited Partnership
824 Market Street, Suite 900
Wilmington, Delaware 19801

Medicus Management Partners
2180 Sand Hill Road
Suite 400
Menlo Park, California 94025


GENERAL PARTNER OF HILLMAN/CHESAPEAKE LIMITED PARTNERSHIP, WHICH
WAS ORGANIZED IN THE U.S.

Wilmington Interstate Corporation.
824 Market Street, Suite 900
Wilmington, Delaware 19801


GENERAL PARTNERS OF MEDICUS MANAGEMENT PARTNERS ALL OF WHOM ARE
U.S. CITIZENS

Frederick J. Dotzler
2180 Sand Hill Road
Suite 400
Menlo Park, California 94025

John Reher
2180 Sand Hill Road
Suite 400
Menlo Park, California 94025

TRUSTEES OF THE HENRY L. HILLMAN TRUST U/A TRUST
DATED NOVEMBER 18, 1985, ALL OF WHOM ARE U.S. CITIZENS

Henry L. Hillman
2000 Grant Building
Pittsburgh, Pennsylvania 15219

Elsie Hilliard Hillman
2000 Grant Building
Pittsburgh, Pennsylvania 15219

C. G. Grefenstette
2000 Grant Building
Pittsburgh, Pennsylvania 15219


TRUSTEES OF THE 1976 JLHS TRUST DATED 12/30/76, THE 1976 AHF TRUST DATED
12/30/76, THE 1976 HLH TRUST DATED 12/30/76 AND THE 1976 WTH TRUST DATED
12/30/76 ALL OF WHOM ARE U.S. CITIZENS

Thomas G. Bigley
One Oxford Centre
28th Floor
Pittsburgh, Pennsylvania 15219

C. G. Grefenstette
2000 Grant Building
Pittsburgh, Pennsylvania 15219

</TABLE>



© 2022 IncJournal is not affiliated with or endorsed by the U.S. Securities and Exchange Commission