CRYOMEDICAL SCIENCES INC
NT 10-K, 1997-03-31
ELECTROMEDICAL & ELECTROTHERAPEUTIC APPARATUS
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March 31, 1997



VIA EDGAR

Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C. 20549

      Re:     Cryomedical Sciences, Inc. - Form 12b-25

Dear Sir or Madam:

      On behalf of our client, Cryomedical Sciences, Inc.
(the "Company"), attached for filing please find a Form
12b-25 relating to the Company's Transition Report on
Form 10-K for the period ended December 29, 1996.



                                                               
      Sincerely yours,

                                                               
      /s/ Leonard J. Breslow

                                                               
      Leonard J. Breslow


LJB/ac
Enclosures

cc:   National Association of Securities Dealers, Inc.
      (w/Enc. - by UPS)
<PAGE>
                  SECURITIES AND EXCHANGE COMMISSION
                         WASHINGTON, DC  20549

                              FORM 12b-25
                                        Commission File Number 0-18170

                      NOTIFICATION OF LATE FILING

    (Check One): [ ] Form 10-K [ ] Form 11-K [ ] Form 20-F [
] Form 10-Q [ ] Form N-SAR

For Period Ended:                                                     
[X] Transition Report on Form 10-K                   [ ] Transition
Report on Form 10-Q
[ ] Transition Report on Form 20-F                   [ ] Transition
Report on Form N-SAR
[ ] Transition Report on Form 11-K
For Transition Period Ended:        December 29, 1996          
                                                                      

    Read attached instruction sheet before preparing form.  Please
print or type.
    Nothing in this form shall be construed to imply that the
Commission has verified any information contained herein.

    If the notification relates to a portion of the filing checked
above, identify the Item(s) to which the notification relates:        

PART I - REGISTRANT INFORMATION
                                      Cryomedical Sciences, Inc.      
Full name of registrant
                                                                      
Former name if applicable
                                        1300 Piccard Drive            
Address of principal executive office (Street and number)
                                        Rockville, Maryland  20850    
City, State and Zip Code

PART II - RULES 12B-25(b) AND (c)

    If the subject report could not be filed without unreasonable
effort or expense and the registrant seeks relief pursuant to Rule
12b-25(b), the following should be completed.  (Check
appropriate box.)

         (a) The reasons described in reasonable detail in Part III
         of this form could not be eliminated without
         unreasonable effort or expense;
         (b) The subject annual report, semi-annual report,
transition report on Form 10-K, Form 20-F, 11-K or Form -
[X]      N-SAR, or portion thereof, will be filed on or before the
fifteenth calendar day following the prescribed due date;             or
the subject quarterly report or transition report on Form 10-Q,
or portion thereof will be filed on or before                 the fifth
calendar day following the prescribed due date; and
         (c) The account's statement or other exhibit required by
         Rule 12b-25(c) has been attached if applicable.

PART III - NARRATIVE

     State below in reasonable detail the reasons why Forms 10-
K, 20-F, 11-K, 10-Q, N-SAR or the transition report portion
thereof could not be filed within the prescribed time period. 
(Attach extra sheets if needed.)

                 The Registrant is unable to timely file its Form
         10-K primarily due to the delays associated with
         changing the Registrant's fiscal year.  The Registrant
         fully intends to file the transition report on Form 10-K
         on or before April 13, 1997.

PART IV - OTHER INFORMATION

     (1)  Name and telephone number of person to contact in
regard to this notification

              Richard Fisher                                     
(301)         417-7070                                                
                 (Name)                                       (Area
code)    (Telephone number)

     (2)  Have all other periodic reports required under Section
13 or 15(d) of the Securities exchange Act of 1934 or Section 30
of the Investment Company Act of 1940 during the preceding 12
months or for such shorter period that the registrant was required
to file such report(s) been filed?  If the answer is no, identify
report(s).

                                                        [X] Yes [ ] No

     (3)  Is it anticipated that any significant change in results of
operations from the corresponding period for the last fiscal year
will be reflected by the earnings statements to be included in the
subject report or portion thereof?

                                                        [ ] Yes [X] No

     If so, attach an explanation of the anticipated change, both
narratively and quantitatively, and, if appropriate, state the
reasons why a reasonable estimate of the results cannot be made.

                                                                               
                                                                      

                                                      Cryomedical
Sciences, Inc.                                                        
             (Name of registrant as specified in charter)

has caused this notification to be signed on its behalf by the
undersigned thereunto duly authorized.

Date  3/28/97           By/s/ Richard Reinhart                        
                                   Dr. Richard Reinhart, Ph.D.,
President and Chief Executive Officer

         Instruction.  The form may be signed by an
     executive officer of the registrant or by any other duly
     authorized representative.  The name and title of the
     person signing the form shall be typed or printed
     beneath the signature.  If the statement is signed on
     behalf of the registrant by an authorized representative
     (other than an executive officer), evidence of the
     representative's authority to sign on behalf of the
     registrant shall be filed with the form.

                               ATTENTION

     Intentional misstatements or omissions of fact constitute
Federal criminal violations (see 18 U.S.C. 1001).


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