MORGAN STANLEY INSTITUTIONAL FUND INC
N-30B-2, 1996-06-07
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<PAGE>
- --------------------------------------------------
OFFICERS AND DIRECTORS
 
Barton M. Biggs             James W. Grisham
  CHAIRMAN OF THE BOARD     VICE PRESIDENT
Frederick B. Whittemore     Michael F. Klein
  VICE-CHAIRMAN OF THE      VICE PRESIDENT
BOARD                       Harold J. Schaaff, Jr.
Warren J. Olsen             VICE PRESIDENT
  PRESIDENT AND DIRECTOR    Joseph P. Stadler
John D. Barrett II          VICE PRESIDENT
  DIRECTOR                  Valerie Y. Lewis
Gerard E. Jones             SECRETARY
  DIRECTOR                  Karl O. Hartmann
Andrew McNally, IV          ASSISTANT SECRETARY
  DIRECTOR                  James R. Rooney
Samuel T. Reeves            TREASURER
  DIRECTOR                  Joanna M. Haigney
Fergus Reid                 ASSISTANT TREASURER
  DIRECTOR
Frederick O. Robertshaw
  DIRECTOR
 
- --------------------------------------------------
INVESTMENT ADVISER AND ADMINISTRATOR
Morgan Stanley Asset Management Inc.
1221 Avenue of the Americas
New York, New York 10020
- --------------------------------------------------
DISTRIBUTOR
Morgan Stanley & Co. Incorporated
1251 Avenue of the Americas
New York, New York 10020
- --------------------------------------------------
CUSTODIANS
The Chase Manhattan Bank, N.A.
770 Broadway
New York, New York 10003
 
Morgan Stanley Trust Company
One Pierrepont Plaza
Brooklyn, New York 11210
- --------------------------------------------------
LEGAL COUNSEL
Morgan, Lewis & Bockius LLP
2000 One Logan Square
Philadelphia, Pennsylvania 19103
- --------------------------------------------------
INDEPENDENT ACCOUNTANTS
Price Waterhouse LLP
1177 Avenue of the Americas
New York, New York 10036
 
- --------------------------------------------------
For current performance, current net asset value, or for assistance with your
account, please contact the Fund at (800) 548-7786. This report is authorized
for distribution only when preceded or accompanied by prospectuses of the Morgan
Stanley Institutional Fund, Inc.
 
[LOGO] MORGAN STANLEY
       INSTITUTIONAL FUND, INC.
       P.O. Box 2798
       Boston, MA 02208-2798
 
[LOGO] MORGAN STANLEY
       INSTITUTIONAL FUND, INC.
 
                         GLOBAL FIXED INCOME PORTFOLIO
                              FIRST QUARTER REPORT
                                 MARCH 31, 1996
<PAGE>
LETTER TO SHAREHOLDERS
- -------
 
The  Global Fixed Income Portfolio aims to  produce an attractive rate of return
by investing  in  fixed  income  securities  issued  by  governments,  agencies,
supranational  entities  and  corporations with  varying  maturities  in various
currencies.
 
For the three  month period  ended March  31, 1996,  the Portfolio  had a  total
return  of -1.34% for the Class  A shares and -1.60% for  the Class B shares, as
compared to a  total return of  -1.75% for  the J.P. Morgan  Traded Global  Bond
Index.  The average annual  total return for  the twelve months  ended March 31,
1996 and for the period from inception on May 1, 1991 through March 31, 1996 was
10.43% and 8.19%, respectively for the Class A shares, as compared to 6.59%  and
10.06%,  respectively for the Index. As of  March 31, 1996, the Portfolio had an
SEC 30-day yield  of 5.97%  for the Class  A shares  and 5.80% for  the Class  B
shares.
 
PERFORMANCE COMPARED TO THE J.P. MORGAN TRADED GLOBAL BOND INDEX(1)
- ----------------------------------------------------
 
<TABLE>
<CAPTION>
                                              TOTAL RETURNS(2)
                                   ---------------------------------------
                                                 ONE      AVERAGE ANNUAL
                                      YTD       YEAR      SINCE INCEPTION
                                   ---------  ---------  -----------------
<S>                                <C>        <C>        <C>
PORTFOLIO--CLASS A...............      -1.34%     10.43%          8.19%
PORTFOLIO--CLASS B(3)............      -1.60        N/A            N/A
INDEX............................      -1.75       6.59          10.06
</TABLE>
 
1.  The J.P. Morgan Traded Global Bond Index is an unmanaged index of securities
    and  includes Australia,  Belgium, Canada, Denmark,  France, Germany, Italy,
    Japan, The Netherlands,  Spain, Sweden,  the United Kingdom  and the  United
    States.
 
2.  Total  returns for the Portfolio reflect  expenses waived and reimbursed, if
    applicable, by the  Adviser. Without  such waiver  and reimbursement,  total
    returns would be lower.
 
3.  The Portfolio began offering Class B shares on January 2, 1996.
 
PAST PERFORMANCE IS NOT PREDICTIVE OF FUTURE PERFORMANCE.
 
- ------------------------------
THE COUNTRY SPECIFIC PERFORMANCE RESULTS PROVIDED ARE FOR INFORMATIONAL PURPOSES
ONLY  AND  SHOULD NOT  BE CONSTRUED  AS  A GUARANTEE  OF THE  PORTFOLIO'S FUTURE
PERFORMANCE. PAST PERFORMANCE  SHOWN IS  NOT PREDICTIVE  OF FUTURE  PERFORMANCE.
INVESTMENT  RETURN  AND PRINCIPAL  VALUE WILL  FLUCTUATE  SO THAT  AN INVESTOR'S
SHARES, WHEN  REDEEMED, MAY  BE WORTH  MORE OR  LESS THAN  THEIR ORIGINAL  COST.
PLEASE  SEE  THE PROSPECTUS  FOR A  DESCRIPTION  OF CERTAIN  RISK CONSIDERATIONS
ASSOCIATED  WITH  INTERNATIONAL  INVESTING.  YIELDS  WILL  FLUCTUATE  AS  MARKET
CONDITIONS CHANGE.
 
Global  bond  markets continued  last  year's strong  performance  into February
before experiencing a sharp setback and increased volatility in the latter  part
of the quarter. Overall local currency returns were mixed, ranging from negative
2.2%  in the UK to positive 2.9% in Italy. The decline in bond prices was caused
by a significant  reversal in  interest rate  expectations as  markets began  to
sense  that a  rebound in  economic growth  was appearing  on the  horizon. This
coincided with a heavy  supply schedule and rising  commodity prices, causing  a
bout of profit taking and some reduction in leveraged positions.
 
The U.S. Treasury market produced an overall return of negative 1.9%. Very short
dated  paper marginally  outperformed cash  over the  quarter but  both duration
effects and  yield  curve  steepening  caused  longer  dated  issues  to  suffer
significant  declines. The mortgage sector generally outperformed Treasuries and
corporate spreads remained tight. The benchmark long bond had rallied below  the
psychological  6.0%  yield  level on  several  occasions in  January,  buoyed by
expectations of lower short rates, a sluggish economy with benign inflation  and
continued hopes for an agreement to reduce the budget deficit. At month end, the
Federal  Reserve fulfilled the market's hopes and  cut the key Fed Funds rate by
another 0.25% to  5.25%, the third  such move  in their easing  cycle. The  U.S.
economy's  profile over the  first two months  of the year  was distorted by the
impact of winter  storms and the  government shutdown. However  in February  Fed
Chairman  Greenspan unsettled the market by  implying the recent weakness of the
economy was temporary,  leading to speculation  that monetary easing  was at  an
end.  A far stronger than expected employment report in March then caused a very
sharp sell off.  Concern over  the impact of  the presidential  election on  the
commitment to reducing the fiscal deficit was also a background negative factor.
Further  evidence of economic strength over  the next few quarters could trigger
another rise in bond yields.  The Fed is now unlikely  to ease policy this  year
unless  higher bond yields  deliver weaker than expected  activity in the second
half. Equally the  market is  probably overpessimistic in  speculating about  an
early  tightening  while inflation  pressures remain  quite weak.  The Portfolio
maintained
 
                                       2
<PAGE>
an underweight allocation to  the market during the  quarter, with a neutral  to
slightly  short duration position. Active use was made of the mortgage sector to
the benefit of performance.
 
The Portfolio was  overweight in  Canadian bonds which  outperformed their  U.S.
counterparts  across the  maturity spectrum  and produced  an average  return of
negative 0.7%. The  Bank of  Canada remained very  accommodative, reducing  loan
rates by 0.5%, with the second cut independent of the U.S. Falling inflation and
increasingly  credible policies  for cutting  the fiscal  deficit were  the main
positives. The Portfolio's small holding  of Australian bonds also  outperformed
the  U.S. The Australian dollar rallied  strongly due to rising commodity prices
and an  attractive  yield. Following  strong  currency gains,  holdings  of  New
Zealand bonds were liquidated.
 
Japanese  bonds largely  avoided the  correction in  U.S. and  European bonds as
foreign investors were already significantly underweight the market and domestic
investors remained  attracted  to the  steepness  of the  yield  curve.  However
overall  returns for the whole quarter were  a meager 0.3% as the market labored
under the negative influences of a low running yield, a buoyant stock market,  a
weaker yen and the ongoing efforts to stimulate the economy. The market remained
fickle  in  its attitude  towards the  outlook for  official interest  rates. In
February, it sold off  when comments from the  Finance Minister implying  savers
were suffering from low rates were seen as signalling a turn in policy. A weaker
than  expected Tankan industrial survey later  corrected some of this short rate
pessimism. The  Portfolio  maintained  a  low exposure  to  the  market  due  to
expectations of a weak yen and because the impact of an extremely lax fiscal and
monetary  stance implied  further upward pressure  on bond  yields. However, the
exposure was increased slightly  as the market and  currency declined. This  was
designed  to lock in relative  gains and reduce risk  relative to the benchmark.
The very  subdued  inflation  background  and  fragile  banking  system  suggest
Japanese rates will stay low for some time.
 
The   fundamental  background  for  European  bonds  remained  constructive,  as
continued slow growth and low  or falling inflation encouraged further  monetary
easing in most countries. As a whole European markets produced the best relative
returns  for the  quarter. However,  with much  good news  already factored into
yields, they were not immune from  developments overseas. After hitting a  yield
low  of 5.78% on 10-year  bonds in January, the  German market weakened, leaving
overall quarterly returns  near zero.  Modest gains  on short  dated bonds  were
offset  by losses on longer issues.  Official interest rates were left unchanged
but the Bundesbank  lowered the  repurchase rate by  0.45% to  3.30%. Since  the
Bundesbank  had centered its easing  argument on weak M3  money supply growth in
1995, the sudden acceleration of M3  from December then cooled further rate  cut
hopes and had a negative impact on bond yields.
 
Significant  yield spread  narrowing of  France over  Germany reflected domestic
investor support of the  market and more optimism  that France would  eventually
achieve  monetary union  with Germany.  Renewed stability  of the  franc allowed
French rates  to  be  steadily  lowered. In  the  U.K.  an  improving  inflation
performance  was used to justify  another cut in base  rates. However the market
suffered from the government's precarious parliamentary circumstances, the  more
advanced   economic  position  relative  to  the  continent,  and  the  possible
consequences of the current BSE beef scare. The higher yielding markets produced
the best returns  over the  quarter, significantly reducing  their yield  spread
over  German bonds.  The Swedish  market returned  2.4%, as  interest rates were
lowered 1.5%, inflation fell  below central bank targets  and fiscal policy  was
tightened.  Italian  bonds  weathered  political  uncertainties  as  a  markedly
improved inflation background, currency  strength and some fiscal  consolidation
increased  the  likelihood  of monetary  easing.  Spanish bonds  also  did well,
returning 2.8%. The inconclusive  result of the general  election did little  to
hold  back the market  as it also  focused on improving  inflation data and rate
cuts. Future  yield-spread  performance within  Europe  will remain  hostage  to
perceptions  of how,  when, and  if Monetary Union  is to  take place. Portfolio
performance was aided by the general  overweighting of European markets and  the
specific overweighting of the higher yielders.
 
On  the foreign exchanges the U.S. dollar  maintained a positive tone during the
quarter but was  confined to  fairly narrow ranges.  It ended  over 3.0%  higher
against  the deutschesmark  and the  yen. This  general appreciation  bucked the
pattern of first  quarter dollar weakness  that has occurred  in the last  three
years.  The dollar  was aided  by the  wide nominal  interest rate differentials
 
                                       3
<PAGE>
existing between  the  U.S.  and Japan/core  European  countries.  The  apparent
divergence  of the  U.S. economic cycle  from the  rest of the  world, the sharp
reversal in U.S. interest rate expectations, the collapse in the Japanese  trade
surplus,  tensions in Taiwan and periodic optimism about European Monetary Union
were all dollar positive. Official Bank of Japan intervention, selling yen  when
it  strengthened, confirmed their desire to keep  it at the softer end of recent
ranges. The yen's decline against the dollar  was hastened at month end by  more
reported  difficulties in the Japanese banking system and optimism that Japanese
investors would increase foreign investment in the new financial year.
 
On the European cross  rates, the deutschemark ended  the quarter lower  against
other  currencies,  reflecting  the  usual  pattern  during  periods  of  dollar
strength. The  Italian lira  rallied 4.0%  from its  depressed year  end  levels
helped   by  widening   interest  rate  differentials   and  improving  economic
fundamentals. Sterling rose 1.4% but was held back by political uncertainty  and
worries  that further rate  cuts would be politically  inspired. The Swiss franc
ended little changed  against the deutschemark  as it's status  as a haven  from
Monetary Union uncertainties was counteracted by meager deposit rates.
 
The  Portfolio maintained an  overweight exposure to  the dollar bloc currencies
through  hedging  from  the  yen  and  core  European  currencies.  This   aided
performance while the forward premiums increased overall yield.
 
As  the year  progresses the  current bountiful  liquidity conditions  that have
supported bond prices are likely  to stimulate stronger growth, implying  weaker
bond  prices  as investors  adjust inflation  risk  premia upwards.  However the
correction in  February/March has  already gone  a long  way toward  positioning
markets  for the  reality of  improving economies.  So long  as actual inflation
stays subdued,  the eventual  turn  in monetary  policy should  not  reverberate
strongly along the yield curve. In relative terms the European markets offer the
best  protection given their poor economic backdrops. The extent of the dollar's
rise in reaction  to recent events  has arguably been  rather disappointing  and
probably signifies that the market is already long of dollars and that much good
news  is  priced in.  However,  the currency  remains  very competitive  and the
international desire to avoid  a renewed fall in  the dollar remains intact.  An
improving   trade  position,   relative  growth  prospects   and  interest  rate
differentials suggest further upside potential.
 
Michael J. Smith
PORTFOLIO MANAGER
Robert M. Smith
PORTFOLIO MANAGER
 
April 1996
 
                                       4
<PAGE>
INVESTMENTS (UNAUDITED)
- ----------
MARCH 31, 1996
<TABLE>
<CAPTION>
     FACE
    AMOUNT                                                VALUE
     (000)                                                (000)
- ---------------                                         ---------
<C>               <S>                                   <C>
FIXED INCOME SECURITIES (91.8%)
  AUSTRALIAN DOLLAR (1.4%)
    GOVERNMENT BONDS (1.4%)
    AUD   1,000    Government of Australia 8.75%,
                    1/15/01                             $     786
            850    Government of Australia 7.50%,
                    7/15/05                                   609
                                                        ---------
                                                            1,395
                                                        ---------
  BRITISH POUND (6.1%)
    GOVERNMENT BONDS (6.1%)
   GBP      500    United Kingdom Treasury 10.00%,
                    2/26/01                                   835
          1,900    United Kingdom Treasury GILT
                    9.75%, 8/27/02                          3,171
          1,500    United Kingdom Treasury 6.75%,
                    11/26/04                                2,100
                                                        ---------
                                                            6,106
                                                        ---------
  CANADIAN DOLLAR (3.7%)
    GOVERNMENT BONDS (3.7%)
   CAD    3,600    Government of Canada 7.50%,
                    12/01/03                                2,646
          1,300    Government of Canada 9.75%,
                    6/01/21                                 1,118
                                                        ---------
                                                            3,764
                                                        ---------
  DANISH KRONE (6.3%)
    GOVERNMENT BONDS (6.3%)
    DKK  17,500    Kingdom of Denmark 8.00%, 11/15/01       3,270
         15,500    Kingdom of Denmark 7.00%, 12/15/04       2,676
          2,000    Kingdom of Denmark 8.00%, 3/15/06          362
                                                        ---------
                                                            6,308
                                                        ---------
  DEUTSCHE MARK (15.7%)
    GOVERNMENT BONDS (15.7%)
    DEM   7,300    German Unity Bond 8.00%, 1/21/02         5,474
          6,350    Treuhandanstalt 6.875%, 6/11/03          4,473
          8,325    Treuhandanstalt 6.75%, 5/13/04           5,784
                                                        ---------
                                                           15,731
                                                        ---------
 
<CAPTION>
     FACE
    AMOUNT                                                VALUE
     (000)                                                (000)
- ---------------                                         ---------
<C>               <S>                                   <C>
 
  ITALIAN LIRA (8.0%)
    GOVERNMENT BONDS (8.0%)
  ITL 1,000,000    Buoni Poliennali Del Tes 8.50%,
                    8/01/04                             $     567
      2,750,000    Republic of Italy 9.50%, 2/01/99         1,719
      8,990,000    Republic of Italy Treasury Bond
                    10.50%, 11/01/00                        5,812
                                                        ---------
                                                            8,098
                                                        ---------
  JAPANESE YEN (9.8%)
    EUROBONDS (6.5%)
  JPY   200,000    Export Import Bank of Japan
                    4.375%, 10/01/03                        2,031
        425,000    International Bank for
                    Reconstruction & Development
                    4.75%, 12/20/04                         4,465
                                                        ---------
                                                            6,496
                                                        ---------
    GOVERNMENT BONDS (3.3%)
        300,000    Japan Development Bank 6.50%,
                    9/20/01                                 3,364
                                                        ---------
                                                            9,860
                                                        ---------
  NETHERLANDS GUILDER (4.0%)
    GOVERNMENT BONDS (4.0%)
   NLG    3,650    Netherlands Government 9.00%,
                    1/15/01                                 2,536
          2,550    Netherlands Government 5.75%,
                    1/15/04                                 1,502
                                                        ---------
                                                            4,038
                                                        ---------
  SPANISH PESETA (5.1%)
    GOVERNMENT BONDS (5.1%)
   ESP   50,000    Spanish Government 12.25%, 3/25/00         443
        562,000    Spanish Government 10.30%, 6/15/02       4,697
                                                        ---------
                                                            5,140
                                                        ---------
  SWEDISH KRONA (1.9%)
    GOVERNMENT BONDS (1.9%)
   SEK   10,500    Swedish Government 13.00%, 6/15/01       1,895
                                                        ---------
  UNITED STATES DOLLAR (29.8%)
    CORPORATE BONDS AND NOTES (6.0%)
 U.S.$      995    Asset Securitization Corp. 7.10%,
                    8/13/29                                   995
</TABLE>
 
                                       5
<PAGE>
<TABLE>
<CAPTION>
     FACE
    AMOUNT                                                VALUE
     (000)                                                (000)
- ---------------                                         ---------
<C>               <S>                                   <C>
  UNITED STATES DOLLAR (CONTINUED)
U.S.$       385    Goldman Sachs Group 6.25%, 2/01/03   $     368
            700    John Hancock 7.375%, 2/15/24               661
            895    LB Commercial Conduit Mortgage
                    Trust 7.144%, 8/25/04                     903
            600    Metropolitan Life Insurance 7.45%,
                    11/01/23                                  550
            600    Prudential Insurance Co., 8.30%,
                    7/01/25                                   607
          2,000    UCFC CMO, Series 1995-C1, Class
                    A3, 6.775%, 9/10/17                     1,974
                                                        ---------
                                                            6,058
                                                        ---------
    EUROBOND (0.5%)
            500    Statens Bostads 8.50%, 5/30/97             513
                                                        ---------
  U.S. GOVERNMENT AND AGENCY OBLIGATIONS (23.3%)
    U.S. TREASURY BONDS
            545    10.75%, 8/15/05                            708
          1,280    8.125%, 8/15/19                          1,464
          1,000    8.75%, 5/15/20                           1,218
                                                        ---------
                                                            3,390
                                                        ---------
    U.S. TREASURY NOTES
          6,450    8.50%, 7/15/97                           6,680
            250    5.25%, 12/31/97                            248
            625    6.75%, 4/30/00                             640
          8,100    7.50%, 11/15/01                          8,596
                                                        ---------
                                                           16,164
                                                        ---------
    U.S. TREASURY STRIPS
          1,600    2/15/98, Principal Only                  1,437
                                                        ---------
    GOVERNMENT NATIONAL MORTGAGE ASSOCIATION
          2,485    7.00%, 2/15/26                           2,422
                                                        ---------
                                                           23,413
                                                        ---------
                                                           29,984
                                                        ---------
TOTAL FIXED INCOME SECURITIES (Cost $93,437)               92,319
                                                        ---------
SHORT-TERM INVESTMENTS (3.5%)
  FRENCH FRANC (2.4%)
    GOVERNMENT BOND (2.4%)
   FRF   11,400    French Treasury Bill 7.75%,
                    4/12/00 (Cost $2,384)                   2,445
                                                        ---------
<CAPTION>
     FACE
    AMOUNT                                                VALUE
     (000)                                                (000)
- ---------------                                         ---------
<C>               <S>                                   <C>
 
  UNITED STATES (1.1%)
    REPURCHASE AGREEMENT (1.1%)
U.S.$     1,093    The Chase Manhattan Bank, N.A.,
                    5.15%, dated 3/29/96, due
                    4/01/96, to be repurchased at
                    $1,093, collateralized by $735
                    United States Treasury Bonds,
                    11.25%, due 2/15/15, valued at
                    $1,118 (Cost $1,093)                $   1,093
                                                        ---------
TOTAL SHORT-TERM INVESTMENTS (Cost $3,477)                  3,538
                                                        ---------
TOTAL INVESTMENTS (95.3%) (Cost $96,914)                   95,857
                                                        ---------
OTHER ASSETS AND LIABILITIES (4.7%)
 Other Assets                                              42,363
 Liabilities                                              (37,585)
                                                        ---------
                                                            4,778
                                                        ---------
NET ASSETS (100%)                                        $100,635
                                                        ---------
                                                        ---------
CLASS A SHARES:
 Net Assets                                               $98,825
 Shares Issued and Outstanding ($0.001 par value)
  (Authorized 500,000,000 shares)                           8,929
 Net Asset Value, Offering and Redemption Price
  Per Share                                                $11.07
                                                        ---------
                                                        ---------
CLASS B SHARES:
 Net Assets                                                $1,810
 Shares Issued and Outstanding ($0.001 par value)
  (Authorized 500,000,000 shares)                             164
 Net Asset Value, Offering and Redemption Price
  Per Share                                                $11.05
                                                        ---------
                                                        ---------
</TABLE>
 
- ----------------------------------
CMO -- Collateralized Mortgage Obligation
 
                                       6


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