MORGAN STANLEY INSTITUTIONAL FUND INC
485BPOS, 1996-04-30
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<PAGE>


   
        As filed with the Securities and Exchange Commission on April 30, 1996
                                                               File No. 33-23166
                                                                        811-5624
    
- --------------------------------------------------------------------------------
                          SECURITIES AND EXCHANGE COMMISSION
                                WASHINGTON, D.C. 20549
                                    --------------
                                      FORM N-1A
                        REGISTRATION STATEMENT (NO. 33-23166)
                                        UNDER
                              THE SECURITIES ACT OF 1933
                           Post-Effective Amendment No. 29
                                         and
                           REGISTRATION STATEMENT UNDER THE
                            INVESTMENT COMPANY ACT OF 1940
                                   Amendment No. 30
                                   ---------------
                       MORGAN STANLEY INSTITUTIONAL FUND, INC.
                  (Exact Name of Registrant as Specified in Charter)
                1221 Avenue of the Americas, New York, New York  10020
                       (Address of Principal Executive Office)
                     Registrant's Telephone Number (800) 548-7786
                           Harold J. Schaaff, Jr., Esquire
                         Morgan Stanley Asset Management Inc.
                1221 Avenue of the Americas, New York, New York  10020
                       (Name and Address of Agent for Service)
                                    --------------
                                      COPIES TO:
    Warren J. Olsen, Esquire                     Richard W. Grant, Esquire
    Morgan Stanley Asset Management Inc.         Morgan, Lewis & Bockius LLP
    1221 Avenue of the Americas                  2000 One Logan Square
    New York, NY 10020                           Philadelphia, PA 19103
                                    --------------

   
         IT IS PROPOSED THAT THIS FILING WILL BECOME EFFECTIVE
              (CHECK APPROPRIATE BOX)
      /X/   IMMEDIATELY UPON FILING PURSUANT TO PARAGRAPH (B)
      / /   ON MAY 1, 1996 PURSUANT TO PARAGRAPH (B)
      / /   60 DAYS AFTER FILING PURSUANT TO PARAGRAPH (A)
      / /   75 DAYS AFTER FILING PURSUANT TO PARAGRAPH (A)
      / /   ON                         PURSUANT TO PARAGRAPH (A) OF RULE 485
              -------------------------
    
                                  ------------------
    Registrant has elected to register an indefinite number of shares pursuant
to Rule 24f-2 under the Investment Company Act of 1940, as amended.  Registrant
filed its Rule 24f-2 notice for the period ended December 31, 1995 on February
15, 1996.
- --------------------------------------------------------------------------------

<PAGE>

                       MORGAN STANLEY INSTITUTIONAL FUND, INC.
                                CROSS REFERENCE SHEET

PART A - INFORMATION REQUIRED IN A PROSPECTUS


 Form N-1A    Location in Prospectus for the Fixed Income, Global Fixed Income,
              Municipal Bond, Mortgage-Backed
ITEM NUMBER   SECURITIES, HIGH YIELD, MONEY MARKET AND MUNICIPAL MONEY MARKET
              PORTFOLIOS


Item 1.  Cover Page -- Cover Page

Item 2.  Synopsis-- Fund Expenses (Estimated for Mortgage-Backed Securities
         Portfolio)

Item 3.  Condensed Financial Information -- Financial Highlights (for the Fixed
         Income, Global Fixed Income, Municipal Bond, High Yield, Money Market
         and Municipal Money Market Portfolios only); Performance Information

Item 4.  General Description of Registrant -- Prospectus Summary; Investment
         Objective and Policies; Additional Investment Information; Investment
         Limitations; General Information

Item 5.  Management of the Fund -- Prospectus Summary; Management of the Fund;
         Portfolio Transactions

Item 5A. Management's Discussion of Fund Performance**

Item 6.  Capital Stock and Other Securities -- Purchase of Shares; Redemption
         of Shares; Shareholder Services; Valuation of Shares; Dividends and
         Capital Gains Distributions; Taxes; General Information

Item 7.  Purchase of Securities Being Offered -- Prospectus Summary; Cover
         Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.  Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
         Shareholder Services

Item 9.  Pending Legal Proceedings -- *

 Form N-1A
ITEM NUMBER   LOCATION IN PROSPECTUS FOR THE SMALL CAP VALUE EQUITY, VALUE
              EQUITY AND BALANCED PORTFOLIOS


Item 1.  Cover Page -- Cover Page

Item 2.  Synopsis -- Fund Expenses

Item 3.  Condensed Financial Information -- Financial Highlights; Performance
         Information

Item 4.  General Description of Registrant -- Prospectus Summary; Investment
         Objective and Policies; Additional Investment Information; Investment
         Limitations; General Information

Item 5.  Management of the Fund -- Prospectus Summary; Management of the Fund;
         Portfolio Transactions

Item 5A. Management's Discussion of Fund Performance**

Item 6.  Capital Stock and Other Securities -- Purchase of Shares; Redemption
         of Shares; Shareholder Services; Valuation of Shares; Dividends and
         Capital Gains Distributions; Taxes; General Information

Item 7.  Purchase of Securities Being Offered -- Prospectus Summary; Cover
         Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.  Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
         Shareholder Services

Item 9.  Pending Legal Proceedings

- -----------------------
*   Omitted since the answer is negative or the Item is not applicable.
**  Information required by Item 5A is contained in the 1995 Annual Report to
    Shareholders, except for the following portfolios which were not in
    operation at December 31, 1995:  Mortgage-Backed Securities, China Growth,
    MicroCap and International Magnum Portfolios.  Information required by Item
    5A for the aforementioned portfolios will be contained in the next Report
    to Shareholders following commencement of operations.

                                          2

<PAGE>

N-1A
ITEM NUMBER   LOCATION IN PROSPECTUS FOR THE ACTIVE COUNTRY ALLOCATION
              PORTFOLIO


Item 1.  Cover Page -- Cover Page

Item 2.  Synopsis -- Fund Expenses

Item 3.  Condensed Financial Information -- Financial Highlights; Performance
         Information

Item 4.  General Description of Registrant -- Prospectus Summary; Investment
         Objective and Policies; Additional Investment Information; Investment
         Limitations; General Information

Item 5.  Management of the Fund -- Prospectus Summary; Management of the Fund;
         Portfolio Transactions

Item 5A. Management's Discussion of Fund Performance**

Item 6.  Capital Stock and Other Securities -- Purchase of Shares; Redemption
         of Shares; Shareholder Services; Valuation of Shares; Dividends and
         Capital Gains Distributions; Taxes; General Information

Item 7.  Purchase of Securities Being Offered -- Prospectus Summary; Cover
         Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.  Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
         Shareholder Services

Item 9.  Pending Legal Proceedings -- *

 Form N-1A
ITEM NUMBER            LOCATION IN PROSPECTUS FOR GOLD PORTFOLIO


Item 1.  Cover Page -- Cover Page

Item 2.  Synopsis -- Fund Expenses

Item 3.  Condensed Financial Information -- Financial Highlights; Performance
         Information

Item 4.  General Description of Registrant -- Prospectus Summary; Investment
         Objective and Policies; Additional Investment Information; Investment
         Limitations; General Information

Item 5.  Management of the Fund -- Prospectus Summary; Management of the Fund;
         Portfolio Transactions

Item 5A. Management's Discussion of Fund Performance**

Item 6.  Capital Stock and Other Securities -- Purchase of Shares; Redemption
         of Shares; Shareholder Services; Valuation of Shares; Dividends and
         Capital Gains Distributions; Taxes; General Information

Item 7.  Purchase of Securities Being Offered -- Prospectus Summary; Cover
         Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.  Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
         Shareholder Services

Item 9.  Pending Legal Proceedings--*

- -------------------------
*   Omitted since the answer is negative or the Item is not applicable.
**  Information required by Item 5A is contained in the 1995 Annual Report to
    Shareholders, except for the following portfolios which were not in
    operation at December 31, 1995:  Mortgage-Backed Securities, China Growth,
    MicroCap and International Magnum Portfolios.  Information required by Item
    5A for the aforementioned portfolios will be contained in the next Report
    to Shareholders following commencement of operations.

                                          3

<PAGE>

FORM N-1A          LOCATION IN PROSPECTUS FOR THE GLOBAL EQUITY, INTERNATIONAL
              EQUITY, INTERNATIONAL SMALL CAP, ASIAN
ITEM NUMBER    EQUITY, EUROPEAN EQUITY, JAPANESE EQUITY AND LATIN AMERICAN
              PORTFOLIOS

Item 1.  Cover Page -- Cover Page

Item 2.  Synopsis -- Fund Expenses

Item 3.  Condensed Financial Information -- Financial Highlights (for the
         Global Equity, International Equity, International Small Cap, Asian
         Equity, European Equity, Japanese Equity and Latin American Portfolios
         only); Performance Information

Item 4.  General Description of Registrant -- Prospectus Summary; Investment
         Objective and Policies; Additional Investment Information; Investment
         Limitations; General Information

Item 5.  Management of the Fund -- Prospectus Summary; Management of the Fund;
         Portfolio Transactions

Item 5A. Management's Discussion of Fund Performance**

Item 6.  Capital Stock and Other Securities -- Purchase of Shares; Redemption
         of Shares; Shareholder Services; Valuation of Shares; Dividends and
         Capital Gains Distributions; Taxes; General Information

Item 7.  Purchase of Securities Being Offered -- Prospectus Summary; Cover
         Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.  Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
         Shareholder Services

Item 9.  Pending Legal Proceedings -- *

 Form N-1A
ITEM NUMBER   LOCATION IN PROSPECTUS FOR THE EMERGING MARKETS AND EMERGING
              MARKETS DEBT PORTFOLIOS

Item 1.  Cover Page -- Cover Page

Item 2.  Synopsis -- Fund Expenses

Item 3.  Condensed Financial Information -- Financial Highlights; Performance
         Information

Item 4.  General Description of Registrant -- Prospectus Summary; Investment
         Objective and Policies; Additional Investment Information; Investment
         Limitations; General Information

Item 5.  Management of the Fund -- Prospectus Summary; Management of the Fund;
         Portfolio Transactions

Item 5A. Management's Discussion of Fund Performance**

Item 6.  Capital Stock and Other Securities -- Purchase of Shares; Redemption
         of Shares; Shareholder Services; Valuation of Shares; Dividends and
         Capital Gains Distributions; Taxes; General Information

Item 7.  Purchase of Securities Being Offered -- Prospectus Summary; Cover
         Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.  Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
         Shareholder Services

Item 9.  Pending Legal Proceedings -- *
- ------------------------

*   Omitted since the answer is negative or the Item is not applicable.
**  Information required by Item 5A is contained in the 1995 Annual Report to
    Shareholders, except for the following portfolios which were not in
    operation at December 31, 1995:  Mortgage-Backed Securities, China Growth,
    MicroCap and International Magnum Portfolios.  Information required by Item
    5A for the aforementioned portfolios will be contained in the next Report
    to Shareholders following commencement of operations.

                                          4

<PAGE>

Form N-1A
ITEM NUMBER   LOCATION IN PROSPECTUS FOR THE CHINA GROWTH PORTFOLIO

Item 1.  Cover Page -- Cover Page

Item 2.  Synopsis -- Fund Expenses (Estimated)

Item 3.  Condensed Financial Information -- Performance Information

Item 4.  General Description of Registrant -- Prospectus Summary; Investment
         Objective and Policies; Additional Investment Information; Investment
         Limitations; General Information

Item 5.  Management of the Fund -- Prospectus Summary; Management of the Fund;
         Portfolio Transactions

Item 5A. Management's Discussion of Fund Performance**

Item 6.  Capital Stock and Other Securities -- Purchase of Shares; Redemption
         of Shares; Shareholder Services; Valuation of Shares; Dividends and
         Capital Gains Distributions; Taxes; General Information

Item 7.  Purchase of Securities Being Offered -- Prospectus Summary; Cover
         Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.  Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
         Shareholder Services

Item 9.  Pending Legal Proceedings -- *

Form N-1A
ITEM NUMBER   LOCATION IN PROSPECTUS FOR THE EQUITY GROWTH, EMERGING GROWTH,
              MICROCAP AND AGGRESSIVE EQUITY PORTFOLIOS

Item 1.  Cover Page -- Cover Page

Item 2.  Synopsis -- Fund Expenses (Estimated for the MicroCap and Aggressive
         Equity Portfolios)

Item 3.  Condensed Financial Information -- Financial Highlights (for the
         Equity Growth, Emerging Growth and Aggressive Equity Portfolios only);
         Performance Information

Item 4.  General Description of Registrant -- Prospectus Summary; Investment
         Objective and Policies; Additional Investment Information; Investment
         Limitations; General Information

Item 5.  Management of the Fund -- Prospectus Summary; Management of the Fund;
         Portfolio Transactions

Item 5A. Management's Discussion of Fund Performance**

Item 6.  Capital Stock and Other Securities -- Purchase of Shares; Redemption
         of Shares; Shareholder Services; Valuation of Shares; Dividends and
         Capital Gains Distributions; Taxes; General Information

Item 7.  Purchase of Securities Being Offered -- Prospectus Summary; Cover
         Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.  Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
         Shareholder Services

Item 9.  Pending Legal Proceedings -- *
- -------------------------
*   Omitted since the answer is negative or the Item is not applicable.
**  Information required by Item 5A is contained in the 1995 Annual Report to
    Shareholders, except for the following portfolios which were not in
    operation at December 31, 1995:  Mortgage-Backed Securities, China Growth,
    MicroCap and International Magnum Portfolios. Information required by Item
    5A for the aforementioned portfolios will be contained in the next Report
    to Shareholders following commencement of operations.

                                          5

<PAGE>

Form N-1A
ITEM NUMBER   LOCATION IN PROSPECTUS FOR THE U.S. REAL ESTATE PORTFOLIO

Item 1.  Cover Page -- Cover Page

Item 2.  Synopsis -- Fund Expenses

Item 3.  Condensed Financial Information -- Financial Highlights; Performance
         Information

Item 4.  General Description of Registrant -- Prospectus Summary; Investment
         Objective and Policies; Additional Investment Information; Investment
         Limitations; General Information

Item 5.  Management of the Fund -- Prospectus Summary; Management of the Fund;
         Portfolio Transactions

Item 5A. Management's Discussion of Fund Performance**

Item 6.  Capital Stock and Other Securities -- Purchase of Shares; Redemption
         of Shares; Shareholder Services; Valuation of Shares; Dividends and
         Capital Gains Distributions; Taxes; General Information

Item 7.  Purchase of Securities Being Offered -- Prospectus Summary; Cover
         Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.  Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
         Shareholder Services

Item 9.  Pending Legal Proceedings -- *

 Form N-1A
ITEM NUMBER   LOCATION IN PROSPECTUS FOR THE INTERNATIONAL MAGNUM PORTFOLIO

Item 1.  Cover Page -- Cover Page

Item 2.  Synopsis -- Fund Expenses (Estimated)

Item 3.  Condensed Financial Information -- Performance Information

Item 4.  General Description of Registrant -- Prospectus Summary; Investment
         Objective and Policies; Additional Investment Information; Investment
         Limitations; General Information

Item 5.  Management of the Fund -- Prospectus Summary; Management of the Fund;
         Portfolio Transactions

Item 5A. Management's Discussion of Fund Performance**

Item 6.  Capital Stock and Other Securities -- Purchase of Shares; Redemption
         of Shares; Shareholder Services; Valuation of Shares; Dividends and
         Capital Gains Distributions; Taxes; General Information

Item 7.  Purchase of Securities Being Offered -- Prospectus Summary; Cover
         Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.  Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
         Shareholder Services

Item 9.  Pending Legal Proceedings -- *
- -------------------------
*   Omitted since the answer is negative or the Item is not applicable.
**  Information required by Item 5A is contained in the 1995 Annual Report to
    Shareholders, except for the following portfolios which were not in
    operation at December 31, 1995:  Mortgage-Backed Securities, China Growth,
    MicroCap and International Magnum Portfolios. Information required by Item
    5A for the aforementioned portfolios will be contained in the next Report
    to Shareholders following commencement of operations.

                                          6

<PAGE>

PART B -      INFORMATION REQUIRED IN A STATEMENT OF ADDITIONAL INFORMATION


 Form N-1A
ITEM NUMBER   LOCATION IN STATEMENT OF ADDITIONAL INFORMATION FOR THE FIXED
              INCOME, GLOBAL FIXED INCOME, MUNICIPAL BOND, MORTGAGE-BACKED
              SECURITIES, HIGH YIELD, MONEY MARKET, MUNICIPAL MONEY MARKET,
              SMALL CAP VALUE EQUITY, VALUE EQUITY, BALANCED, ACTIVE COUNTRY
              ALLOCATION, GOLD, GLOBAL EQUITY, INTERNATIONAL EQUITY,
              INTERNATIONAL MAGNUM, INTERNATIONAL SMALL CAP, ASIAN EQUITY,
              EUROPEAN EQUITY, JAPANESE EQUITY, LATIN AMERICAN, EMERGING
              MARKETS, EMERGING MARKETS DEBT, CHINA GROWTH, EQUITY GROWTH,
              EMERGING GROWTH, MICROCAP, AGGRESSIVE EQUITY AND U.S. REAL ESTATE
              PORTFOLIOS.

Item 10. Cover Page -- Cover Page

Item 11. Table of Contents -- Cover Page

Item 12. General Information and History -- *

Item 13. Investment Objective and Policies -- Investment Objectives and
         Policies; Investment Limitations

Item 14. Management of the Fund -- Management of the Fund

Item 15. Control Persons and Principal Holders of Securities -- Management of
         the Fund; General
         Information

Item 16. Investment Advisory and Other Services -- Management of the Fund

Item 17. Brokerage Allocation -- *

Item 18. Capital Stock and Other Securities -- General Information

Item 19. Purchase, Redemption and Pricing of Securities Being Offered --
         Purchase of Shares; Redemption of Shares; Net Asset Value; General
         Information

Item 20. Tax Status -- Federal Tax Treatment of Forward Currency and Futures
         Contracts

Item 21. Underwriters -- *

Item 22. Calculation of Performance Data -- Performance Information

Item 23. Financial Statements -- Financial Statements

PART C   OTHER INFORMATION

         Part C contains the information required by the terms contained
         therein under the items set forth in the form.


- ------------------------
*   Omitted since the answer is negative or the Item is not applicable.

                                          7
<PAGE>

     The Prospectus for the China Growth Portfolio, included as part of
Post-Effective Amendment No. 25 to the Registration Statement on Form N1-A of 
Morgan Stanley Institutional Fund, Inc. (File No. 33-23166) filed with the 
Securities and Exchange Commission via EDGAR on August 1, 1995, is hereby 
incorporated by reference as if set forth in full herein.

<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
 -----------------------------------------------------------------------------
 
                             FIXED INCOME PORTFOLIO
                         GLOBAL FIXED INCOME PORTFOLIO
                            MUNICIPAL BOND PORTFOLIO
                      MORTGAGE-BACKED SECURITIES PORTFOLIO
                              HIGH YIELD PORTFOLIO
                             MONEY MARKET PORTFOLIO
                        MUNICIPAL MONEY MARKET PORTFOLIO
 
                               PORTFOLIOS OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
 
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
                                ----------------
   
    Morgan  Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company or mutual fund, which offers redeemable shares  in
a    series   of   diversified   and   non-diversified   investment   portfolios
("portfolios").  The  Fund   currently  consists   of  twenty-eight   portfolios
representing  a  broad range  of  investment choices.  The  Fund is  designed to
provide clients with attractive alternatives for meeting their investment needs.
This prospectus  (the "Prospectus")  pertains to  the Class  A and  the Class  B
shares of the Fixed Income, Global Fixed Income, Municipal Bond, Mortgage-Backed
Securities  and High  Yield Portfolios (the  "Non-Money Portfolios")  and to the
Class A shares of  the Money Market and  Municipal Money Market Portfolios  (the
"Money  Portfolios") (collectively, the  "Portfolios"). On January  2, 1996, the
Non-Money Portfolios began offering  two classes of shares,  the Class A  shares
and  the Class B shares, except for the Money Market, Municipal Money Market and
International Small Cap Portfolios which only  offer Class A shares. All  shares
of  the Portfolios  owned prior  to January  2, 1996  were redesignated  Class A
shares on January 2, 1996. The Class  A and Class B shares currently offered  by
the Non-Money Portfolios have different minimum investment requirements and fund
expenses.  Shares of the portfolios are offered with no sales charge or exchange
or redemption fee (with the exception of the International Small Cap Portfolio).
    
 
   
    THE HIGH  YIELD  PORTFOLIO  INVESTS  PREDOMINANTLY  IN  LOWER  RATED  BONDS,
COMMONLY  REFERRED TO AS "JUNK  BONDS." BONDS OF THIS  TYPE ARE CONSIDERED TO BE
SPECULATIVE WITH REGARD  TO THE  PAYMENT OF  INTEREST AND  RETURN OF  PRINCIPAL.
INVESTORS  SHOULD CAREFULLY  ASSESS THE RISKS  ASSOCIATED WITH  AN INVESTMENT IN
THIS  PORTFOLIO.  SEE  "RISK  FACTORS  RELATING  TO  INVESTING  IN  HIGH   YIELD
SECURITIES."
    
 
   
    INVESTMENTS  IN THE MONEY  MARKET AND MUNICIPAL  MONEY MARKET PORTFOLIOS ARE
NEITHER INSURED NOR  GUARANTEED BY THE  U.S. GOVERNMENT. THERE  IS NO  ASSURANCE
THAT  THE MONEY  MARKET AND  MUNICIPAL MONEY MARKET  PORTFOLIOS WILL  BE ABLE TO
MAINTAIN A STABLE NET ASSET VALUE OF $1.00 PER SHARE.
    
 
   
    INVESTORS SHOULD NOTE THAT THE GLOBAL  FIXED INCOME PORTFOLIO MAY INVEST  UP
TO  10% OF ITS TOTAL ASSETS  IN RESTRICTED SECURITIES. INVESTMENTS IN RESTRICTED
SECURITIES IN EXCESS OF  5% OF A  PORTFOLIO'S TOTAL ASSETS  MAY BE CONSIDERED  A
SPECULATIVE  ACTIVITY, MAY INVOLVE GREATER RISK AND MAY INCREASE THE PORTFOLIO'S
EXPENSES.
    
 
   
    The Fund is designed  to meet the investment  needs of discerning  investors
who  place a premium on quality and  personal service. With Morgan Stanley Asset
Management  Inc.  as   Adviser  and   Administrator  (the   "Adviser"  and   the
"Administrator")  and with Morgan Stanley  & Co. Incorporated ("Morgan Stanley")
as Distributor, the  Fund makes available  to institutional and  high net  worth
individual  investors a series  of portfolios which  benefit from the investment
expertise and commitment to  excellence associated with  Morgan Stanley and  its
affiliates.
    
 
   
    This Prospectus is designed to set forth concisely the information about the
Fund  that a prospective investor should know  before investing and it should be
retained for future reference. The  Fund offers additional portfolios which  are
described  in other prospectuses and under  "Prospectus Summary" below. The Fund
currently offers the following portfolios:  (i) GLOBAL AND INTERNATIONAL  EQUITY
- --  Active Country Allocation, Asian  Equity, Emerging Markets, European Equity,
Global Equity, Gold, International  Equity, International Magnum,  International
Small  Cap, Japanese Equity  and Latin American Portfolios;  (ii) U.S. EQUITY --
Aggressive Equity, Emerging  Growth, Equity  Growth, MicroCap,  Small Cap  Value
Equity,  U.S. Real  Estate and Value  Equity Portfolios; (iii)  EQUITY AND FIXED
INCOME -- Balanced Portfolio; (iv) FIXED INCOME -- Emerging Markets Debt,  Fixed
Income,   Global  Fixed  Income,  High  Yield,  Mortgage-Backed  Securities  and
Municipal Bond Portfolios; and  (v) MONEY MARKET --  Money Market and  Municipal
Money Market Portfolios. Additional information about the Fund is contained in a
"Statement  of Additional Information" dated May  1, 1996, which is incorporated
herein  by  reference.   The  Statement  of   Additional  Information  and   the
prospectuses  pertaining to the other portfolios  of the Fund are available upon
request and without charge  by writing or  calling the Fund  at the address  and
telephone number set forth above.
    
 
   
  THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES AND
  EXCHANGE  COMMISSION  OR  ANY  STATE  SECURITIES  COMMISSION,  NOR  HAS THE
   SECURITIES AND  EXCHANGE COMMISSION  OR ANY  STATE SECURITIES  COMMISSION
    PASSED   UPON  THE  ACCURACY  OR   ADEQUACY  OF  THIS  PROSPECTUS.  ANY
     REPRESENTATION   TO   THE    CONTRARY   IS    A   CRIMINAL    OFFENSE.
    
 
   
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1996.
    
<PAGE>
                                 FUND EXPENSES
 
    The  following table illustrates the expenses and fees that a shareholder of
the Portfolios indicated below will incur:
 
   
<TABLE>
<CAPTION>
                                                                 GLOBAL               MORTGAGE-                        MUNICIPAL
                                                       FIXED      FIXED    MUNICIPAL   BACKED      HIGH       MONEY      MONEY
                                                      INCOME     INCOME      BOND     SECURITIES   YIELD     MARKET     MARKET
SHAREHOLDER TRANSACTION EXPENSES                     PORTFOLIO  PORTFOLIO  PORTFOLIO  PORTFOLIO  PORTFOLIO  PORTFOLIO  PORTFOLIO
- ---------------------------------------------------  ---------  ---------  ---------  ---------  ---------  ---------  ---------
<S>                                                  <C>        <C>        <C>        <C>        <C>        <C>        <C>
Maximum Sales Load Imposed on Purchases
  Class A..........................................    None       None       None       None       None       None       None
  Class B..........................................    None       None       None       None       None        N/A        N/A
Maximum Sales Load Imposed on Reinvested Dividends
  Class A..........................................    None       None       None       None       None       None       None
  Class B..........................................    None       None       None       None       None        N/A        N/A
Deferred Sales Load
  Class A..........................................    None       None       None       None       None       None       None
  Class B..........................................    None       None       None       None       None        N/A        N/A
Redemption Fees
  Class A..........................................    None       None       None       None       None       None       None
  Class B..........................................    None       None       None       None       None        N/A        N/A
Exchange Fees
  Class A..........................................    None       None       None       None       None       None       None
  Class B..........................................    None       None       None       None       None       None       None
</TABLE>
    
 
   
<TABLE>
<CAPTION>
                                                                GLOBAL               MORTGAGE-                        MUNICIPAL
                                                     FIXED      FIXED     MUNICIPAL   BACKED      HIGH      MONEY      MONEY
                                                     INCOME     INCOME      BOND     SECURITIES  YIELD      MARKET     MARKET
ANNUAL FUND OPERATING EXPENSES                      PORTFOLIO  PORTFOLIO  PORTFOLIO  PORTFOLIO  PORTFOLIO  PORTFOLIO  PORTFOLIO
- --------------------------------------------------  --------   --------   --------   --------   --------   --------   --------
(AS A PERCENTAGE OF AVERAGE NET ASSETS)
<S>                                                 <C>        <C>        <C>        <C>        <C>        <C>        <C>
Management Fee (Net of Fee Waivers)***
  Class A.........................................    0.21%      0.19%      0.07%      0.20%      0.42%      0.30%*     0.30%*
  Class B.........................................    0.21%      0.19%      0.07%      0.20%      0.42%      N/A        N/A
12b-1 Fees
  Class A.........................................    None       None       None       None       None       None       None
  Class B.........................................    0.15%**    0.15%**    0.25%      0.25%      0.25%      N/A        N/A
Other Expenses
  Class A.........................................    0.24%      0.31%      0.38%      0.25%      0.33%      0.21%      0.22%
  Class B.........................................    0.24%      0.31%      0.38%      0.25%      0.33%      N/A        N/A
                                                    --------   --------   --------   --------   --------   --------   --------
Total Operating Expenses (Net of Fee Waivers)***
  Class A.........................................    0.45%      0.50%      0.45%      0.45%      0.75%      0.51%*     0.52%*
  Class B.........................................    0.70%      0.65%      0.70%      0.70%      1.00%      N/A        N/A
                                                    --------   --------   --------   --------   --------   --------   --------
                                                    --------   --------   --------   --------   --------   --------   --------
</TABLE>
    
 
- ------------------------------
   
  *No fee waiver or expense reimbursement is in effect for this Portfolio.
    
   
 **The Distributor has agreed to waive 0.10% of the 0.25% distribution fee it is
   entitled to receive from this Portfolio.
    
   
***The Adviser has  agreed to waive  its management fees  and/or reimburse  each
   Portfolio,  if necessary, if  such fees would  cause any of  the total annual
   operating expenses  of the  Portfolios to  exceed a  specified percentage  of
   their  respective  average  daily  net  assets.  Set  forth  below,  for each
   Portfolio as applicable, are the management fees and total operating expenses
   absent such fee waivers and/or expense reimbursements as a percent of average
   daily net assets of the Class A  shares of the Portfolios and Class B  shares
   of the Non-Money Portfolios, respectively.
    
 
                                       2
<PAGE>
 
   
<TABLE>
<CAPTION>
                                                                                           TOTAL OPERATING EXPENSES
                                                                                              ABSENT FEE WAIVERS
                                                                    MANAGEMENT FEES      ----------------------------
PORTFOLIO                                                         ABSENT FEE WAIVERS        CLASS A       CLASS B+
- --------------------------------------------------------------  -----------------------  -------------  -------------
<S>                                                             <C>                      <C>            <C>
Fixed Income..................................................             0.35%              0.59%           0.74%
Global Fixed Income...........................................             0.40%              0.71%           0.86%
Municipal Bond................................................             0.35%              0.73%           0.98%
Mortgage-Backed Securities....................................             0.35%              0.60%+          0.85%
High Yield....................................................             0.50%              0.83%           1.08%
Money Market..................................................             0.30%              0.51%++          N/A
Municipal Money Market........................................             0.30%              0.52%++          N/A
</TABLE>
    
 
- ------------------------
   
 + Estimated.
    
   
++ No fee waiver or expense reimbursement is in effect for this Portfolio.
    
 
   
    These reductions became or will become effective as of the inception of each
Portfolio.  As a result of these reductions, the Investment Advisory Fees stated
above are lower than the contractual fees stated under "Management of the Fund."
For further information on Fund expenses see "Management of the Fund."
    
 
   
    The purpose of the  table above is to  assist the investor in  understanding
the  various  expenses  that an  investor  in  the Fund  will  bear  directly or
indirectly. The Class A fees and expenses for the Portfolios are based on actual
figures for  the fiscal  year ended  December 31,  1995. The  Class A  fees  and
expenses for the Mortgage-Backed Securities Portfolio are based on estimates and
assume  that  the  average  daily  net  assets of  the  Class  A  shares  of the
Mortgage-Backed Securities Portfolio will be  $50,000,000. The Class B fees  and
expenses  of each Non-Money Portfolio are  based on estimates, assuming that the
average daily net assets of the Class B shares of each Non-Money Portfolio  will
be  $50,000,000. "Other Expenses" include Board of Directors' fees and expenses,
amortization of organizational costs, professional fees, filing fees, and  costs
for  shareholders reports. Due to the continuous nature of Rule 12b-1 fees, long
term Class  B shareholders  may pay  more  than the  equivalent of  the  maximum
front-end sales charges otherwise permitted by the Rules of Fair Practice of the
National Association of Securities Dealers, Inc. ("NASD").
    
 
                                       3
<PAGE>
    The  following  example illustrates  the expenses  that you  would pay  on a
$1,000 investment assuming (1) a 5% annual rate of return and (2) redemption  at
the  end of each time period. As noted in the table above, the Portfolios charge
no redemption  fees  of  any kind.  The  following  example is  based  on  total
operating expenses of the Portfolios after fee waivers.
 
   
<TABLE>
<CAPTION>
                                           1        3        5       10
                                         YEAR     YEARS    YEARS    YEARS
                                         -----    -----    -----    -----
<S>                                      <C>      <C>      <C>      <C>
Fixed Income Portfolio
  Class A.............................   $  5     $ 14     $ 25     $ 57
  Class B.............................   $  6     $ 19     $ 33     $ 75
Global Fixed Income
  Class A.............................   $  5     $ 16     $ 28     $ 63
  Class B.............................   $  7     $ 21     $ 36     $ 81
Municipal Bond Portfolio
  Class A.............................   $  5     $ 14       25       57
  Class B.............................   $  7     $ 22       39       87
Mortgage-Backed Securities Portfolio
  Class A.............................   $  5     $ 14      *        *
  Class B.............................   $  7     $ 22      *        *
High Yield Portfolio
  Class A.............................   $  8     $ 24     $ 42     $ 93
  Class B.............................   $ 10     $ 32     $ 55     $122
Money Market Portfolio
  Class A.............................   $  5     $ 16     $ 29     $ 64
Municipal Money Market Portfolio
  Class A.............................   $  5     $ 17     $ 29     $ 65
</TABLE>
    
 
- ------------------------
   
* Because the Mortgage-Backed Securities Portfolio was not operational as of the
  Fund's  fiscal  year  end, the  Fund  has  not projected  expenses  beyond the
  three-year period shown.
    
 
    THIS EXAMPLE SHOULD  NOT BE CONSIDERED  A REPRESENTATION OF  PAST OR  FUTURE
EXPENSES  OR  PERFORMANCE. ACTUAL  EXPENSES MAY  BE GREATER  OR LESS  THAN THOSE
SHOWN.
 
    The Fund intends  to continue to  comply with all  state laws that  restrict
investment  company expenses. Currently, the most restrictive state law requires
that the aggregate annual expenses of an investment company shall not exceed two
and one-half percent (2 1/2%)  of the first $30  million of average net  assets,
two  percent (2%)  of the next  $70 million of  average net assets,  and one and
one-half percent  (1  1/2%) of  the  remaining  net assets  of  such  investment
company.
 
   
    The  Adviser has agreed to a reduction in  the amounts payable to it, and to
reimburse any Portfolio,  if necessary, if  in any  fiscal year the  sum of  the
Portfolio's expenses exceed the limit set by applicable state law.
    
 
                                       4
<PAGE>
                              FINANCIAL HIGHLIGHTS
 
   
    The following tables provides financial highlights for the Class A shares of
the  Fixed Income, Global Fixed Income, Municipal Bond, High Yield, Money Market
and Municipal Money  Market Portfolios for  each of the  periods presented.  The
audited  financial highlights for the  Class A shares for  the fiscal year ended
December 31, 1995 are  part of the Fund's  financial statements which appear  in
the  Fund's  December  31, 1995  Annual  Report  to Shareholders  and  which are
included in  the Fund's  Statement of  Additional Information.  The  Portfolios'
financial  highlights for each of  the periods in the  five years ended December
31, 1995 have  been audited by  Price Waterhouse LLP,  whose unqualified  report
thereon  is also included in the Statement of Additional Information. Additional
performance information for the Class A shares of the Fixed Income, Global Fixed
Income, Municipal  Bond, High  Yield, Money  Market and  Municipal Money  Market
Portfolios is included in the Annual Report. The Annual Report and the financial
statements  therein,  along with  the Statement  of Additional  Information, are
available at no cost from the Fund at the address and telephone number noted  on
the  cover page of  this Prospectus. Financial highlights  are not available for
the new Class B shares since they were not offered as of December 31, 1995.  The
Mortgage-Backed  Securities  Portfolio was  not operational  as of  December 31,
1995. Subsequent to  October 31, 1992  (the Fund's prior  fiscal year end),  the
Fund  changed  its fiscal  year end  to December  31. The  following information
should be read in conjunction with the financial statements and notes thereto.
    
 
                                       5
<PAGE>
                             FIXED INCOME PORTFOLIO
 
   
<TABLE>
<CAPTION>
                             MAY 15,                    TWO MONTHS
                            1991* TO     YEAR ENDED       ENDED        YEAR ENDED     YEAR ENDED     YEAR ENDED
                           OCTOBER 31,   OCTOBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,
                              1991          1992           1992           1993           1994           1995
                           -----------   -----------   ------------   ------------   ------------   ------------
<S>                        <C>           <C>           <C>            <C>            <C>            <C>
NET ASSET VALUE,
 BEGINNING OF PERIOD.....  $   10.00     $   10.55     $    10.92     $    10.93     $    11.05     $     9.82
                           -----------   -----------   ------------   ------------   ------------   ------------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment
   Income (1)............       0.22          0.69           0.10           0.54           0.59           0.72
  Net Realized and
   Unrealized Gain/(Loss)
   on Investments........       0.49          0.39           0.01           0.41          (0.92)          1.06
                           -----------   -----------   ------------   ------------   ------------   ------------
  Total from Investment
   Operations............       0.71          1.08           0.11           0.95          (0.33)          1.78
                           -----------   -----------   ------------   ------------   ------------   ------------
DISTRIBUTIONS
  Net Investment
   Income................      (0.16)        (0.69)         (0.10)         (0.56)         (0.53)         (0.79)
  In Excess of Net
   Investment Income.....         --            --             --          (0.01)            --             --
  Net Realized Gain......         --         (0.02)            --          (0.26)         (0.37)            --
  In Excess of Net
   Realized Gain.........         --            --             --             --          (0.00)+           --
                           -----------   -----------   ------------   ------------   ------------   ------------
  Total Distributions....      (0.16)        (0.71)         (0.10)         (0.83)         (0.90)         (0.79)
                           -----------   -----------   ------------   ------------   ------------   ------------
NET ASSET VALUE, END OF
 PERIOD..................  $   10.55     $   10.92     $    10.93     $    11.05     $     9.82     $    10.81
                           -----------   -----------   ------------   ------------   ------------   ------------
                           -----------   -----------   ------------   ------------   ------------   ------------
TOTAL RETURN.............       7.12%        10.61%          1.02%          9.07%         (3.10)%        18.76%
                           -----------   -----------   ------------   ------------   ------------   ------------
                           -----------   -----------   ------------   ------------   ------------   ------------
RATIOS AND SUPPLEMENTAL
 DATA:
Net Assets, End of Period
 (Thousands).............  $  72,326     $ 146,546     $  154,210     $  240,668     $  209,331     $  162,527
Ratio of Expenses to
 Average Net
 Assets (1)(2)...........       0.45%**       0.45%          0.45%**        0.45%          0.45%          0.45%
Ratio of Net Investment
 Income to Average Net
 Assets (1)(2)...........       7.29%**       6.59%          5.56%**        4.97%          5.73%          6.85%
Portfolio Turnover
 Rate....................         48%          105%            15%           240%           388%           172%
</TABLE>
    
 
- --------------------------
   
(1) Effect of voluntary expense limitation during the period:
    
 
   
<TABLE>
<S>                        <C>           <C>           <C>            <C>            <C>            <C>
  Per share benefit to
   net investment
   income................  $    0.01     $    0.02     $     0.01     $     0.02     $     0.01     $     0.01
Ratios before expense
 limitation:
  Expenses to Average Net
   Assets................       0.81%**       0.59%          0.75%**        0.60%          0.58%          0.59%
  Net Investment Income
   to Average Net
   Assets................       6.93%**       6.45%          5.26%**        4.82%          5.60%          6.71%
</TABLE>
    
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to receive a management  fee calculated at  an annual rate  of 0.35% of  the
    average  daily net  assets of  the Fixed  Income Portfolio.  The Adviser has
    agreed to  waive a  portion of  this fee  and/or reimburse  expenses of  the
    Portfolio  to the extent that the  total operating expenses of the Portfolio
    exceed 0.45% of the average daily net assets of the Class A shares and 0.70%
    of the average daily net assets of  the Class B shares. In the period  ended
    October  31, 1991,  the year  ended October 31,  1992, the  two month period
    ended December 31, 1992, the years  ended December 31, 1993, 1994 and  1995,
    the  Adviser  waived management  fees  and/or reimbursed  expenses totalling
    $69,000, $165,000,  $74,000,  $307,000,  $276,000,  $142,000  and  $247,000,
    respectively, for the Fixed Income Portfolio.
    
   
 * Commencement of Operations.
    
   
** Annualized.
    
   
 + Amount is less than $0.01 per share.
    
 
                                       6
<PAGE>
                         GLOBAL FIXED INCOME PORTFOLIO
 
   
<TABLE>
<CAPTION>
                             MAY 1,                     TWO MONTHS
                            1991* TO     YEAR ENDED       ENDED        YEAR ENDED     YEAR ENDED     YEAR ENDED
                           OCTOBER 31,   OCTOBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,
                              1991          1992           1992           1993           1994           1995
                           -----------   -----------   ------------   ------------   ------------   ------------
<S>                        <C>           <C>           <C>            <C>            <C>            <C>
NET ASSET VALUE,
 BEGINNING OF PERIOD.....  $   10.00     $   10.61     $    11.41     $    11.26     $    11.68     $    10.29
                           -----------   -----------   ------------   ------------   ------------   ------------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment
   Income (1)............       0.16          0.53           0.14           0.69           0.70           0.76
  Net Realized and
   Unrealized Gain (Loss)
   on Investments........       0.45          0.55          (0.29)          0.90          (1.38)          1.15
                           -----------   -----------   ------------   ------------   ------------   ------------
  Total from Investment
   Operations............       0.61          1.08          (0.15)          1.59          (0.68)          1.91
                           -----------   -----------   ------------   ------------   ------------   ------------
DISTRIBUTIONS
  Net Investment
   Income................         --         (0.27)            --          (0.79)         (0.40)         (0.98)
  In Excess of Net
   Investment Income.....         --            --             --          (0.22)            --             --
  Net Realized Gain......         --         (0.01)            --          (0.16)         (0.31)            --
                           -----------   -----------   ------------   ------------   ------------   ------------
  Total Distributions....         --         (0.28)            --          (1.17)         (0.71)         (0.98)
                           -----------   -----------   ------------   ------------   ------------   ------------
NET ASSET VALUE, END OF
 PERIOD..................  $   10.61     $   11.41     $    11.26     $    11.68     $    10.29     $    11.22
                           -----------   -----------   ------------   ------------   ------------   ------------
                           -----------   -----------   ------------   ------------   ------------   ------------
TOTAL RETURN.............       6.10%        10.29%         (1.31)%        15.34%         (6.08)%        19.32%
                           -----------   -----------   ------------   ------------   ------------   ------------
                           -----------   -----------   ------------   ------------   ------------   ------------
RATIOS AND SUPPLEMENTAL
 DATA:
Net Assets, End of Period
 (Thousands).............  $  28,236     $  94,847     $   92,897     $  172,468     $  130,675     $  102,852
Ratio of Expenses to
 Average Net
 Assets (1)(2)...........       0.50%**       0.50%          0.50%**        0.50%          0.50%          0.50%
Ratio of Net Investment
 Income to Average Net
 Assets (1)(2)...........       7.24%**       6.92%          6.99%**        5.99%          6.34%          6.79%
Portfolio Turnover
 Rate....................         20%          144%             9%           108%           171%           207%
</TABLE>
    
 
- --------------------------
   
(1) Effect of voluntary expense limitation during the period:
    
 
   
<TABLE>
<S>                        <C>           <C>           <C>            <C>            <C>            <C>
  Per share benefit to
   net investment
   income................  $    0.02     $    0.03     $     0.01     $     0.02     $     0.02     $     0.02
Ratios before expense
 limitation:
  Expenses to Average Net
   Assets................       1.62%**       0.86%          0.90%**        0.70%          0.66%          0.71%
  Net Investment Income
   to Average Net
   Assets................       6.12%**       6.56%          6.59%**        5.79%          6.18%          6.58%
</TABLE>
    
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to  receive a management  fee calculated at  an annual rate  of 0.40% of the
    average daily net assets of the  Global Fixed Income Portfolio. The  Adviser
    has  agreed to waive a portion of  this fee and/or reimburse expenses of the
    Portfolio to the extent that the  total operating expenses of the  Portfolio
    exceed 0.50% of the average daily net assets of the Class A shares and 0.75%
    of  the average daily net assets of the Class B shares. In the fiscal period
    ended October 31,  1991, the  year ended October  31, 1992,  the two  months
    ended  December 31, 1992, the years ended  December 31, 1993, 1994 and 1995,
    the Adviser  waived management  fees  and/or reimbursed  expenses  totalling
    $67,000,  $201,000, $64,000, $260,000,  $238,000 and $204,000, respectively,
    for the Global Fixed Income Portfolio.
    
   
 * Commencement of Operations.
    
   
** Annualized.
    
 
                                       7
<PAGE>
                            MUNICIPAL BOND PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                    PERIOD FROM
                                                                    JANUARY 18,
                                                                      1995* TO
                                                                    DECEMBER 31,
                                                                        1995
                                                                    ------------
<S>                                                                 <C>
NET ASSET VALUE, BEGINNING OF PERIOD.............................   $    10.00
                                                                    ------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income..........................................         0.44
  Net Realized and Unrealized Gain on Investments................         0.42
                                                                    ------------
  Total from Investment Operations...............................         0.86
                                                                    ------------
DISTRIBUTIONS
  Net Investment Income..........................................        (0.45)
  In Excess of Net Investment Income.............................        (0.00)+
  Net Realized Gain..............................................        (0.04)
                                                                    ------------
  Total Distributions............................................        (0.49)
                                                                    ------------
NET ASSET VALUE, END OF PERIOD...................................   $    10.37
                                                                    ------------
                                                                    ------------
TOTAL RETURN.....................................................         8.80%
                                                                    ------------
                                                                    ------------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)............................   $   45,869
Ratio of Expenses to Average Net Assets (1)(2)...................         0.45%**
Ratio of Net Investment Income to Average Net Assets (1)(2)......         4.61%**
Portfolio Turnover Rate..........................................          180%
</TABLE>
    
 
- ------------------------
   
(1) Effect of voluntary expense limitation during the period:
    
 
   
<TABLE>
<S>                                                                 <C>
  Per share benefit to net investment income.....................   $     0.03
Ratios before expense limitation:
  Expenses to Average Net Assets.................................         0.73%**
  Net Investment Income to Average Net Assets....................         4.33%**
</TABLE>
    
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to receive a management  fee calculated at  an annual rate  of 0.35% of  the
    average  daily net assets  of the Municipal Bond  Portfolio. The Adviser has
    agreed to  waive a  portion of  this fee  and/or reimburse  expenses of  the
    Portfolio  to the extent that the  total operating expenses of the Portfolio
    exceed 0.45% of the average daily net assets of the Class A shares and 0.70%
    of the average daily net assets of  the Class B shares. In the period  ended
    December  31, 1995, the Adviser waived management and/or reimbursed expenses
    totalling $119,000 for the Municipal Bond Portfolio.
    
   
 * Commencement of Operations.
    
   
** Annualized.
    
   
 + Amount is less than $0.01 per share.
    
 
                                       8
<PAGE>
                              HIGH YIELD PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                          SEPTEMBER    TWO MONTHS
                                          28, 1992*       ENDED      YEAR ENDED    YEAR ENDED    YEAR ENDED
                                          TO OCTOBER    DECEMBER      DECEMBER      DECEMBER      DECEMBER
                                           31, 1992     31, 1992      31, 1993      31, 1994      31, 1995
                                          ----------   -----------   -----------   -----------   -----------
<S>                                       <C>          <C>           <C>           <C>           <C>
NET ASSET VALUE, BEGINNING OF PERIOD....  $ 10.00      $   9.77      $   9.95      $  11.16      $   9.55
                                          ----------   -----------   -----------   -----------   -----------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1).............     0.08          0.14          0.90          0.97          1.14
  Net Realized and Unrealized
   Gain/(Loss) on Investments...........    (0.31)         0.19          1.21         (1.40)         0.97
                                          ----------   -----------   -----------   -----------   -----------
  Total from Investment Operations......    (0.23)         0.33          2.11         (0.43)         2.11
                                          ----------   -----------   -----------   -----------   -----------
DISTRIBUTIONS
  Net Investment Income.................       --         (0.15)        (0.90)        (0.97)        (1.20)
  Net Realized Gain.....................       --            --            --         (0.21)           --
                                          ----------   -----------   -----------   -----------   -----------
  Total Distributions...................       --         (0.15)        (0.90)        (1.18)        (1.20)
                                          ----------   -----------   -----------   -----------   -----------
NET ASSET VALUE, END OF PERIOD            $  9.77      $   9.95      $  11.16      $   9.55      $  10.46
                                          ----------   -----------   -----------   -----------   -----------
                                          ----------   -----------   -----------   -----------   -----------
TOTAL RETURN                               (2.30)%         3.41%        22.11%      (4.18)%         23.35%
                                          ----------   -----------   -----------   -----------   -----------
                                          ----------   -----------   -----------   -----------   -----------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)...  $16,950      $ 20,194      $ 74,500      $ 97,223      $ 62,245
Ratio of Expenses to Average Net Assets
 (1)(2).................................     0.75%**       0.75%**       0.75%         0.75%         0.75%
Ratio of Net Investment Income to
 Average Net Assets (1)(2)..............     9.89%**       8.96%**       8.70%         9.42%        11.09%
Portfolio Turnover Rate.................        9%           24%          104%           74%           90%
</TABLE>
    
 
- --------------------------
   
(1) Effect of voluntary expense limitation during the period:
    
 
   
<TABLE>
<S>                                       <C>          <C>           <C>           <C>           <C>
  Per share benefit to net investment
   income...............................  $  0.01      $   0.01      $   0.02      $  0.001      $   0.01
Ratios before expense limitation:
  Expenses to Average Net Assets........     1.23%**       1.62%**       0.96%         0.76%         0.83%
  Net Investment Income to Average Net
   Assets...............................     9.41%**       8.09%**       8.49%         9.41%        11.01%
</TABLE>
    
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to receive a management  fee calculated at  an annual rate  of 0.50% of  the
    average daily net assets of the High Yield Portfolio. The Adviser has agreed
    to waive a portion of this fee and/or reimburse expenses of the Portfolio to
    the  extent that the total operating  expenses of the Portfolio exceed 0.75%
    of the average  daily net  assets of  the Class A  shares and  1.00% of  the
    average  daily net assets of the Class B shares. In the period ended October
    31, 1992,  the two  months ended  December  31, 1992,  and the  years  ended
    December  31, 1993, 1994 and 1995, the Adviser waived management fees and/or
    reimbursed expenses totalling $22,000, $27,000, $82,000, $7,000 and $55,000,
    respectively, for the High Yield Portfolio.
    
   
 * Commencement of Operations.
    
   
** Annualized.
    
 
                                       9
<PAGE>
                             MONEY MARKET PORTFOLIO
 
   
<TABLE>
<CAPTION>
                         NOVEMBER                                            TWO MONTHS
                         15, 1988*    YEAR ENDED   YEAR ENDED   YEAR ENDED      ENDED      YEAR ENDED    YEAR ENDED    YEAR ENDED
                        TO OCTOBER     OCTOBER      OCTOBER      OCTOBER      DECEMBER      DECEMBER      DECEMBER      DECEMBER
                         31, 1989      31, 1990     31, 1991     31, 1992     31, 1992      31, 1993      31, 1994      31, 1995
                        -----------   ----------   ----------   ----------   -----------   -----------   -----------   -----------
<S>                     <C>           <C>          <C>          <C>          <C>           <C>           <C>           <C>
NET ASSET VALUE,
 BEGINNING OF
 PERIOD...............  $  1.000      $ 1.000      $ 1.000      $ 1.000      $  1.000      $  1.000      $  1.000      $  1.000
                        -----------   ----------   ----------   ----------   -----------   -----------   -----------   -----------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment
   Income (1).........     0.085        0.079        0.062        0.039         0.005         0.027         0.040         0.054
                        -----------   ----------   ----------   ----------   -----------   -----------   -----------   -----------
DISTRIBUTIONS
  Net Investment
   Income.............    (0.085)      (0.079)      (0.062)      (0.039)       (0.005)       (0.027)       (0.040)       (0.054)
  In Excess of Net
   Investment
   Income.............        --           --           --           --            --         0.000+           --            --
                        -----------   ----------   ----------   ----------   -----------   -----------   -----------   -----------
  Total
   Distributions......    (0.085)      (0.079)      (0.062)      (0.039)       (0.005)       (0.027)       (0.040)       (0.054)
                        -----------   ----------   ----------   ----------   -----------   -----------   -----------   -----------
NET ASSET VALUE, END
 OF PERIOD............  $  1.000      $ 1.000      $ 1.000      $ 1.000      $  1.000      $  1.000      $  1.000      $  1.000
                        -----------   ----------   ----------   ----------   -----------   -----------   -----------   -----------
                        -----------   ----------   ----------   ----------   -----------   -----------   -----------   -----------
TOTAL RETURN..........      8.81%        8.16%        6.37%        3.77%         0.50%         2.76%         3.84%         5.51%
                        -----------   ----------   ----------   ----------   -----------   -----------   -----------   -----------
                        -----------   ----------   ----------   ----------   -----------   -----------   -----------   -----------
RATIOS AND
 SUPPLEMENTAL DATA:
Net Assets, End of
 Period (Thousands)...  $158,582      $516,182     $607,087     $612,968     $599,172      $657,163      $690,503      $836,693
Ratio of Expenses to
 Average Net Assets
 (1)(2)...............      0.55%**      0.55%        0.53%        0.52%         0.55%**       0.53%         0.49%         0.51%
Ratio of Net
 Investment Income to
 Average Net Assets
 (1)(2)...............      8.80%**      7.87%        6.11%        3.74%         3.11%**       2.71%         3.77%         5.37%
Portfolio Turnover
 Rate.................       N/A          N/A          N/A          N/A           N/A           N/A           N/A           N/A
</TABLE>
    
 
- ------------------------------
   
(1) Effect of voluntary expense limitation during the period:
    
 
   
<TABLE>
<S>                     <C>           <C>          <C>          <C>          <C>           <C>           <C>           <C>
  Per share benefit to
   net investment
   income.............  $  0.001      $ 0.000          N/A          N/A      $  0.000+     $  0.000           N/A           N/A
Ratios before expense
 limitation:
  Expenses to Average
   Net Assets.........      0.64%**      0.58%         N/A          N/A          0.59%**       0.54%          N/A           N/A
  Net Investment
   Income to Average
   Net Assets.........      8.71%**      7.85%         N/A          N/A          3.07%**       2.70%          N/A           N/A
</TABLE>
    
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to receive a management  fee calculated at  an annual rate  of 0.30% of  the
    average  daily net  assets of  the Money  Market Portfolio.  The Adviser has
    agreed to  waive a  portion of  this fee  and/or reimburse  expenses of  the
    Portfolio  to the extent that the  total operating expenses of the Portfolio
    exceed 0.55% of  the average daily  net assets  of the Class  A shares.  The
    Adviser did not waive fees or reimburse expenses for the years ended October
    31,  1991, October 31, 1992, December 31, 1994 and December 31, 1995. In the
    period ended October  31, 1989,  the year ended  October 31,  1990, the  two
    months  ended December 31,  1992 and the  year ended December  31, 1993, the
    Adviser  waived  management  fees  and  /or  reimbursed  expenses  totalling
    approximately  $110,000, $75,000, $37,000 and $18,000, respectively, for the
    Money Market Portfolio.
    
   
 * Commencement of Operations.
    
   
** Annualized.
    
   
 + Amount if less than $0.001 per share.
    
 
                                       10
<PAGE>
                        MUNICIPAL MONEY MARKET PORTFOLIO
 
   
<TABLE>
<CAPTION>
                         FEBRUARY                                            TWO MONTHS
                         10, 1989*    YEAR ENDED   YEAR ENDED   YEAR ENDED      ENDED      YEAR ENDED    YEAR ENDED    YEAR ENDED
                        TO OCTOBER     OCTOBER      OCTOBER      OCTOBER      DECEMBER      DECEMBER      DECEMBER      DECEMBER
                         31, 1989      31, 1990     31, 1991     31, 1992     31, 1992      31, 1993      31, 1994      31, 1995
                        -----------   ----------   ----------   ----------   -----------   -----------   -----------   -----------
<S>                     <C>           <C>          <C>          <C>          <C>           <C>           <C>           <C>
NET ASSET VALUE,
 BEGINNING OF
 PERIOD...............  $  1.000      $ 1.000      $ 1.000      $ 1.000      $  1.000      $  1.000      $  1.000      $  1.000
                        -----------   ----------   ----------   ----------   -----------   -----------   -----------   -----------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment
   Income (1).........     0.046        0.054        0.043        0.026         0.004         0.019         0.020         0.034
                        -----------   ----------   ----------   ----------   -----------   -----------   -----------   -----------
DISTRIBUTIONS
  Net Investment
   Income.............    (0.046)      (0.054)      (0.043)      (0.026)       (0.004)       (0.019)       (0.020)       (0.034)
  In Excess of Net
   Investment
   Income.............        --           --           --           --            --        (0.000)+          --            --
                        -----------   ----------   ----------   ----------   -----------   -----------   -----------   -----------
  Total
   Distributions......    (0.046)      (0.054)      (0.043)      (0.026)       (0.004)       (0.019)       (0.020)       (0.034)
                        -----------   ----------   ----------   ----------   -----------   -----------   -----------   -----------
NET ASSET VALUE, END
 OF PERIOD............  $  1.000      $ 1.000      $ 1.000      $ 1.000      $  1.000      $  1.000      $  1.000      $  1.000
                        -----------   ----------   ----------   ----------   -----------   -----------   -----------   -----------
                        -----------   ----------   ----------   ----------   -----------   -----------   -----------   -----------
TOTAL RETURN..........       4.6%        5.51%        4.35%        2.74%         0.37%         1.91%         2.44%         3.44%
                        -----------   ----------   ----------   ----------   -----------   -----------   -----------   -----------
                        -----------   ----------   ----------   ----------   -----------   -----------   -----------   -----------
RATIOS AND
 SUPPLEMENTAL DATA:
  Net Assets, End of
   Period
   (Thousands)........  $ 38,540      $102,195     $166,953     $206,691     $208,866      $266,524      $359,444      $451,519
Ratio of Expenses to
 Average Net Assets
 (1)(2)...............      0.32%**      0.51%        0.56%        0.55%         0.57%**       0.54%         0.51%         0.52%
Ratio of Net
 Investment Income to
 Average Net Assets
 (1)(2)...............      6.05%**      5.38%        4.18%        2.66%         2.31%**       1.89%         2.42%         3.38%
Portfolio Turnover
 Rate.................       N/A          N/A          N/A          N/A           N/A           N/A           N/A           N/A
</TABLE>
    
 
- ------------------------------
   
(1) Effect of voluntary expense limitation during the period:
    
 
   
<TABLE>
<S>                     <C>           <C>          <C>          <C>          <C>           <C>           <C>           <C>
  Per share benefit to
   net investment
   income.............  $  0.002      $ 0.001          N/A          N/A      $  0.000+     $  0.000+          N/A           N/A
Ratios before expense
 limitation:
  Expenses to Average
   Net Assets.........      0.74%**      0.63%         N/A          N/A          0.67%**       0.56%          N/A           N/A
  Net Investment
   Income to Average
   Net Assets.........      5.63%**      5.26%         N/A          N/A          2.21%**       1.87%          N/A           N/A
</TABLE>
    
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to receive a management  fee calculated at  an annual rate  of 0.30% of  the
    average  daily  net  assets of  the  Municipal Money  Market  Portfolio. The
    Adviser has agreed to waive a portion of this fee and/or reimburse  expenses
    of  the Portfolio  to the  extent that the  total operating  expenses of the
    Portfolio exceed  0.57% of  the average  daily  net assets  of the  Class  A
    shares.  The Adviser did not waive fees  or reimburse expenses for the years
    ended October 31, 1991, October 31, 1992, December 31, 1994 and December 31,
    1995. In the period ended October 31, 1989, the year ended October 31, 1990,
    the two months ended December 31, 1992 and the year ended December 31, 1993,
    the Adviser  waived management  fees  and/or reimbursed  expenses  totalling
    approximately  $75,000, $92,000, $36,000 and  $46,000, respectively, for the
    Municipal Money Market Portfolio.
    
   
 * Commencement of Operations.
    
   
** Annualized.
    
   
 + Amount is less than $0.001 per share.
    
 
                                       11
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
 
   
    The  Fund consists  of twenty-eight  portfolios, offering  institutional and
high net worth individual investors a broad range of investment choices  coupled
with  the  advantages of  a  no-load mutual  fund  with Morgan  Stanley  and its
affiliates  providing  customized   services  as   Adviser,  Administrator   and
Distributor.  Each portfolio offers Class A shares and, except the International
Small Cap, Money Market and Municipal Money Market Portfolios, also offers Class
B shares. Each portfolio has its own investment objective and policies  designed
to meet its specific goals. The investment objective of each Portfolio described
in this Prospectus is as follows:
    
 
    - The FIXED INCOME PORTFOLIO seeks to produce a high total return consistent
      with  the preservation of capital by  investing in a diversified portfolio
      of fixed income securities.
 
    - The GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real rate
      of return while preserving capital by investing in fixed income securities
      of issuers throughout the world, including U.S. issuers.
 
    - The MUNICIPAL BOND  PORTFOLIO seeks  to produce  a high  level of  current
      income  consistent  with  preservation  of  principal  through  investment
      primarily in municipal obligations, the  interest on which is exempt  from
      federal income tax.
 
    - The  MORTGAGE-BACKED SECURITIES PORTFOLIO seeks to produce as high a level
      of current income  as is consistent  with the preservation  of capital  by
      investing  primarily  in  a  variety  of  investment-grade mortgage-backed
      securities.
 
    - The HIGH YIELD PORTFOLIO seeks to maximize total return by investing in  a
      diversified  portfolio of high yield fixed  income securities that offer a
      yield above  that generally  available  on debt  securities in  the  three
      highest rating categories of the recognized rating services.
 
    - The  MONEY MARKET PORTFOLIO seeks to  maximize current income and preserve
      capital while maintaining  high levels of  liquidity through investing  in
      high  quality money  market instruments  with remaining  maturities of one
      year or less.
 
    - The MUNICIPAL MONEY MARKET PORTFOLIO seeks to maximize current  tax-exempt
      income  and preserve  capital while  maintaining high  levels of liquidity
      through investing in high quality money market instruments with  remaining
      maturities of one year or less which are exempt from federal income tax.
 
    The  other portfolios of the Fund  are described in other prospectuses which
may be obtained from the Fund at  the address and telephone number noted on  the
cover  page of  this Prospectus.  The objectives  of these  other portfolios are
listed below:
 
    GLOBAL AND INTERNATIONAL EQUITY:
 
    - The  ACTIVE   COUNTRY  ALLOCATION   PORTFOLIO  seeks   long-term   capital
      appreciation by investing in accordance with country weightings determined
      by  the Adviser  in equity  securities of  non-U.S. issuers  which, in the
      aggregate, replicate broad country indices.
 
    - The  ASIAN  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
      investing primarily in equity securities of Asian issuers.
 
    - The CHINA GROWTH PORTFOLIO seeks to provide long-term capital appreciation
      by investing primarily in the equity securities of issuers in The People's
      Republic of China, Hong Kong and Taiwan.
 
                                       12
<PAGE>
    - The  EMERGING MARKETS  PORTFOLIO seeks  long-term capital  appreciation by
      investing primarily in equity securities of emerging country issuers.
 
    - The EUROPEAN  EQUITY PORTFOLIO  seeks  long-term capital  appreciation  by
      investing primarily in equity securities of European issuers.
 
    - The  GLOBAL  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation by
      investing primarily in equity securities of issuers throughout the  world,
      including U.S. issuers.
 
    - The  GOLD  PORTFOLIO  seeks long-term  capital  appreciation  by investing
      primarily in equity securities of foreign and domestic issuers engaged  in
      gold-related activities.
 
    - The INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of non-U.S. issuers.
 
   
    - The INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of non-U.S. issuers in accordance
      with  EAFE  country (as  defined in  "Investment Objectives  and Policies"
      below) weightings determined by the Adviser.
    
 
   
    - The INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital appreciation
      by investing  primarily  in equity  securities  of non-U.S.  issuers  with
      equity market capitalizations of less than $1 billion.
    
 
    - The  JAPANESE  EQUITY PORTFOLIO  seeks  long-term capital  appreciation by
      investing primarily in equity securities of Japanese issuers.
 
    - The LATIN  AMERICAN  PORTFOLIO  seeks long-term  capital  appreciation  by
      investing  primarily in  equity securities  of Latin  American issuers and
      debt securities  issued or  guaranteed by  Latin American  governments  or
      governmental entities.
 
    U.S. EQUITY:
 
    - The  AGGRESSIVE EQUITY  PORTFOLIO seeks capital  appreciation by investing
      primarily in corporate equity and equity-linked securities.
 
    - The EMERGING  GROWTH PORTFOLIO  seeks  long-term capital  appreciation  by
      investing  primarily  in growth-oriented  equity  securities of  small- to
      medium-sized corporations.
 
    - The EQUITY  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation  by
      investing  primarily in  growth-oriented equity  securities of  medium and
      large capitalization companies.
 
    - The MICROCAP PORTFOLIO seeks  long-term capital appreciation by  investing
      primarily in growth-oriented equity securities of small corporations.
 
    - The  SMALL CAP VALUE EQUITY PORTFOLIO seeks high long-term total return by
      investing in  undervalued  equity  securities of  small-  to  medium-sized
      companies.
 
    - The  U.S. REAL  ESTATE PORTFOLIO  seeks to  provide above  average current
      income and long-term capital appreciation by investing primarily in equity
      securities of companies in the  U.S. real estate industry, including  real
      estate investment trusts.
 
    - The  VALUE EQUITY PORTFOLIO seeks high total return by investing in equity
      securities which the Adviser  believes to be  undervalued relative to  the
      stock market in general at the time of purchase.
 
    EQUITY AND FIXED INCOME:
 
    - The BALANCED PORTFOLIO seeks high total return while preserving capital by
      investing  in  a combination  of undervalued  equity securities  and fixed
      income securities.
 
                                       13
<PAGE>
    FIXED INCOME:
 
    - The EMERGING  MARKETS  DEBT  PORTFOLIO  seeks  high  current  income,  and
      secondarily,   capital  appreciation,  by   investing  primarily  in  debt
      securities of government, government-related and corporate issuers located
      in emerging countries.
 
INVESTMENT MANAGEMENT
 
   
    Morgan Stanley Asset Management  Inc., a wholly  owned subsidiary of  Morgan
Stanley  Group  Inc.,  which,  together  with  its  affiliated  asset management
companies, at December 31, 1995 had approximately $57.4 billion in assets  under
management  as  an  investment  manager  or  as  a  fiduciary  adviser,  acts as
investment adviser to the  Fund and each of  its portfolios. See "Management  of
the Fund -- Investment Adviser" and "Management of the Fund -- Administrator."
    
HOW TO INVEST
 
   
    Class  A shares of each  Portfolio are offered directly  to investors at net
asset value with no sales commission  or 12b-1 charges. Class B shares,  offered
only  by the Non-Money Portfolios, are offered  at net asset value with no sales
commission, but with  a 12b-1 fee,  which is accrued  daily and paid  quarterly,
equal  to 0.25% of the Class B shares' average daily net assets on an annualized
basis. While each  Money Portfolio  expects to maintain  a net  asset value  per
share  of  $1.00, there  can be  no  assurance that  either Money  Portfolio can
maintain such net asset value per share. Share purchases may be made by  sending
investments  directly  to  the Fund  or  through  the Distributor.  Shares  in a
Portfolio account opened prior to January 2, 1996 were designated Class A shares
on January 2, 1996. For a Non-Money Portfolio account opened on or after January
2, 1996 (a "New Non-Money Account"), the minimum initial investment is  $500,000
for  Class  A  shares and  $100,000  for  Class B  shares.  The  minimum initial
investment for  each  Money Portfolio  is  $50,000. Certain  exceptions  to  the
foregoing  minimums apply to (1) shares  in a Non-Money Portfolio account opened
prior to January 2, 1996 (each, a "Pre-1996 Non-Money Account") with a value  of
$100,000  or more  on March  1, 1996  (a "Grandfathered  Class A  Account"); (2)
Portfolio accounts held by officers of  the Adviser and its affiliates; and  (3)
certain  advisory or asset  allocation accounts, such  as Total Funds Management
accounts, managed by  Morgan Stanley  or its affiliates,  including the  Adviser
("Managed  Accounts"). The Adviser reserves the  right in its sole discretion to
determine which of such advisory or  asset allocation accounts shall be  Managed
Accounts.  For information regarding Managed Accounts please contact your Morgan
Stanley account representative or the Fund  at the telephone number provided  on
the  cover of  this Prospectus.  Shares in a  Pre-1996 Non-Money  Account with a
value of less than $100,000 on March 1, 1996 (a "Grandfathered Class B Account")
converted to Class B shares on March 1, 1996. The minimum investment levels  may
be  waived  at the  discretion  of the  Adviser  for (i)  certain  employees and
customers of Morgan  Stanley or  its affiliates and  certain trust  departments,
brokers,  dealers,  agents,  financial planners,  financial  services  firms, or
investment advisers that have entered into  an agreement with Morgan Stanley  or
its  affiliates; and (ii) retirement and  deferred compensation plans and trusts
used to fund such plans, including, but not limited to, those defined in Section
401(a), 403(b) or  457 of the  Internal Revenue  Code of 1986,  as amended,  and
"rabbi trusts". See "Purchase of Shares -- Minimum Investment and Account Sizes;
Conversion from Class A to Class B Shares."
    
 
                                       14
<PAGE>
   
    The  minimum  subsequent investment  for  each Portfolio  account  is $1,000
(except for automatic reinvestment of dividends and capital gains  distributions
for  which there is no minimum). Such  subsequent investments will be applied to
purchase additional  shares  in  the same  class  held  by a  shareholder  in  a
Portfolio account. See "Purchase of Shares -- Additional Investments."
    
   
HOW TO REDEEM
    
 
   
    Class  A shares or Class  B shares of the Portfolios  may be redeemed at any
time, without cost, at the net asset value per share of shares of the applicable
class next determined after  receipt of the  redemption request. The  redemption
price may be more or less than the purchase price. Certain redemptions may cause
involuntary  redemption or automatic conversion. Class  A or Class B shares held
in New Non-Money Accounts are  subject to involuntary redemption if  shareholder
redemption(s)  of such  shares reduces  the value of  such account  to less than
$100,000 for a continuous 60-day  period. Involuntary redemption does not  apply
to  Managed Accounts, Grandfathered  Class A Accounts  and Grandfathered Class B
Accounts, regardless of  the value of  such accounts.  Class A shares  in a  New
Non-Money Account will convert to Class B shares if shareholder redemption(s) of
such  shares  reduces the  value of  such account  to less  than $500,000  for a
continuous 60-day period. Class B shares in a New Non-Money Account will convert
to Class  A shares  if shareholder  purchases of  additional Class  B shares  or
market  activity cause  the value  of the  Class B  shares in  the New Non-Money
Account to increase  to $500,000  or more. If  a shareholder  reduces its  total
investment  in Class  A shares of  a Money  Portfolio to less  than $10,000, the
investment may be  subject to  redemption. See  "Purchase of  Shares --  Minimum
Account Sizes and Involuntary Redemption of Shares" and "Redemption of Shares."
    
 
RISK FACTORS
 
   
    The  investment policies of each of  the Portfolios entail certain risks and
considerations of which an  investor should be aware.  The Fixed Income,  Global
Fixed Income, High Yield and Money Market Portfolios may invest in securities of
foreign  issuers, which  are subject to  certain risks  not typically associated
with U.S. securities. In addition, the High Yield Portfolio may invest in  lower
rated  and unrated securities which are  subject to risk factors. In particular:
(1) adverse economic  and corporate changes  and changes in  interest rates  may
have  a greater  impact on issuers  of such  securities and may  lead to greater
price volatility,  and  (2) such  securities  may  be more  difficult  to  value
accurately  or  sell in  the secondary  market.  See "Investment  Objectives and
Policies" and "Additional Investment  Information." In addition, each  Portfolio
may  invest in repurchase agreements, lend its portfolio securities and purchase
securities on  a  when-issued  or  delayed  delivery  basis.  The  Money  Market
Portfolio  may invest in  reverse repurchase agreements.  Each Portfolio, except
the Global Fixed Income Portfolio, may  invest in futures contracts and  options
on  futures  contracts. The  Fixed Income,  Global Fixed  Income and  High Yield
Portfolios may invest in  forward foreign currency  exchange contracts to  hedge
currency  risks  associated  with  investment  in  non-U.S.  dollar  denominated
securities. The  Municipal  Money  Market  Portfolio may  invest  in  "puts"  on
municipal  bonds  or notes  and the  Municipal Bond  and Municipal  Money Market
Portfolios may invest  up to  20% of such  Portfolios' total  assets in  taxable
securities.  Each of these  investment strategies involves  specific risks which
are  described  under  "Investment  Objectives  and  Policies"  and  "Additional
Investment Information" herein and under "Investment Objectives and Policies" in
the Statement of Additional Information.
    
 
                                       15
<PAGE>
                       INVESTMENT OBJECTIVES AND POLICIES
 
    The investment objective of each Portfolio is described below, together with
the  policies the Fund employs in its  efforts to achieve these objectives. Each
Portfolio's investment  objective  is a  fundamental  policy which  may  not  be
changed without the approval of a majority of the Portfolio's outstanding voting
securities. There is no assurance that the Portfolio will attain its objectives.
The  investment  policies described  below are  not fundamental  policies unless
otherwise noted and may be changed without shareholder approval.
 
THE FIXED INCOME PORTFOLIO
 
   
    The Portfolio  seeks to  produce a  high total  return consistent  with  the
preservation  of capital  by investing primarily  in a  diversified portfolio of
U.S. Government  securities,  corporate bonds  (including  competitively  priced
Eurodollar bonds), mortgage-backed securities and other fixed income securities,
such  as certificates of deposit and short-term money market instruments. Short-
and intermediate-term bonds form the core of the Portfolio, and long-term  bonds
(i.e.,  those  with maturities  over ten  years) are  purchased on  a short-term
opportunistic basis when the Adviser  believes they will enhance return  without
significantly  increasing risk. The Adviser sets an annual target rate of return
for the Portfolio based on current and projected market and economic  conditions
and  manages the Portfolio conservatively -- primarily through gradual shifts in
maturities in attempting to achieve this target rate.
    
 
    Emphasis in the  Portfolio will  be on U.S.  Government and  mortgage-backed
securities.  Typically, between 50% and 75% of the Portfolio's total assets will
be invested in these securities. When  corporate bonds are purchased, they  will
generally  be rated  in the two  highest rating categories  by Moody's Investors
Service, Inc. ("Moody's") (Aaa or Aa) or Standard & Poor's Ratings Group ("S&P")
(AAA or AA). The  Portfolio will not  invest in a corporate  security if at  the
time of investment the security is not rated at least investment grade by either
rating  agency. Although  U.S. dollar-denominated securities  will represent the
major portion of the Portfolio,  up to 15% of the  Portfolio may be invested  in
foreign  currency  obligations of  corporate and  governmental issuers  when the
Adviser feels that the currency component and underlying market  characteristics
of such obligations will add value to the Portfolio.
 
    Any remaining assets of the Portfolio not invested as described above may be
invested  in  certain  securities or  obligations  as set  forth  in "Additional
Investment Information" below.
 
THE GLOBAL FIXED INCOME PORTFOLIO
 
    The Global Fixed Income Portfolio seeks  to produce an attractive real  rate
of  return while preserving  capital by investing in  fixed income securities of
U.S. and foreign issuers  denominated in U.S. dollars  and in other  currencies.
The  Portfolio seeks to  achieve its objectives by  investing in U.S. government
securities, foreign government securities, securities of supranational entities,
Eurobonds, and corporate  bonds with varying  maturities denominated in  various
currencies.  In  selecting  portfolio  securities,  the  Adviser  evaluates  the
currency, market, and individual features of the securities being considered for
investment. At least 65% of the total  assets of the Portfolio will be  invested
in fixed income securities under normal circumstances.
 
    The  Adviser seeks  to minimize  investment risk  by investing  only in high
quality debt  securities.  U.S. Government  securities  that the  Portfolio  may
invest  in include obligations issued or guaranteed by the U.S. Government, such
as U.S.  Treasury securities,  as well  as those  backed by  the full-faith  and
credit  of the  U.S., such  as obligations  of the  Government National Mortgage
Association and The Export-Import Bank. The Portfolio
 
                                       16
<PAGE>
may also invest in obligations issued or guaranteed by U.S. Government  agencies
or instrumentalities where the Portfolio must look principally to the issuing or
guaranteeing  agency  for  ultimate  repayment.  The  Portfolio  may  invest  in
obligations issued  or guaranteed  by foreign  governments and  their  political
subdivisions,  authorities, agencies or  instrumentalities, and by supranational
entities (such as  the World Bank,  The European Economic  Community, The  Asian
Development  Bank  and the  European Coal  and  Steel Community).  Investment in
foreign government  securities will  be limited  to those  of developed  nations
which  the  Adviser  believes  to  pose  limited  credit  risk.  These countries
currently include Australia, Austria, Belgium, Canada, Denmark, Finland, France,
Ireland, Italy,  Japan, Luxembourg,  Netherlands,  New Zealand,  Norway,  Spain,
Sweden, Switzerland, The United Kingdom and Germany. Corporate and supranational
obligations  which the Portfolio will invest in will be limited to those rated A
or better by  Moody's, S&P or  IBCA Ltd., or  if unrated, to  those that are  of
comparable  quality  in the  determination  of the  Board  of Directors  and the
Adviser.
 
    The Adviser's approach to multicurrency fixed-income management is strategic
and value-based and designed to produce  an attractive real rate of return.  The
Adviser's  assessment of the bond markets and currencies is based on an analysis
of real interest rates.  Current nominal yields of  securities are adjusted  for
inflation  prevailing  in each  currency sector  using an  analysis of  past and
projected inflation rates.  The Portfolio's  aim is  to invest  in bond  markets
which offer the most attractive real returns relative to inflation.
 
    The  Portfolio  will  have  a  neutral  investment  position  in medium-term
securities (i.e., those  with a remaining  maturity of between  three and  seven
years)  and  will respond  to  changing interest  rate  levels by  shortening or
lengthening portfolio  maturity through  investment in  longer or  shorter  term
instruments.  For example,  the Portfolio  will respond  to high  levels of real
interest  rates  through  a  lengthening  in  portfolio  maturity.  Current  and
historical yield spreads among the three main market segments -- the Government,
Foreign  and  Euro  markets --  guide  the  Adviser's selection  of  markets and
particular securities within those markets.  The analysis of currencies is  made
independent  of the analysis of markets. Value in foreign exchange is determined
by relative purchasing power parity of a given currency. The Portfolio seeks  to
invest in currencies currently undervalued based on purchasing power parity. The
Adviser  analyzes  current  account  and capital  account  performance  and real
interest rates to adjust for shorter-term currency flows.
 
    The Portfolio seeks to maintain portfolio turnover at a low level.  Although
the  Portfolio's primary objective is not  to invest for short-term trading, the
Portfolio will seek to take advantage of trading opportunities as they arise  to
the  extent  that they  are consistent  with the  Portfolio's objectives.  It is
anticipated that the Portfolio's  annual turnover rate will  not exceed 100%  in
normal  circumstances, but the Portfolio's annual turnover rate may exceed 100%.
An annual  turnover  rate that  exceeds  100% involves  correspondingly  greater
brokerage  commissions or transaction costs which  will be borne directly by the
Portfolio. In addition, high portfolio turnover may result in more capital gains
which would be taxable to the shareholders of the Portfolio.
 
    The  Portfolio  will  occasionally  enter  into  forward  currency  exchange
contracts.  These are  used to  hedge foreign  currency exchange  exposures when
required. See  "Forward  Currency Exchange  Contracts"  in this  Prospectus  and
"Investment  Objectives and Policies --  Forward Currency Exchange Contracts" in
the Statement of Additional Information.
 
    Any remaining assets of the Portfolio not invested as described above may be
invested in  certain  securities or  obligations  as set  forth  in  "Additional
Investment Information" below.
 
                                       17
<PAGE>
THE MUNICIPAL BOND PORTFOLIO
 
    The  Portfolio  seeks high  current income  consistent with  preservation of
principal  through   investment  in   a   portfolio  consisting   primarily   of
intermediate- and long-term investment grade Municipal Obligations, the interest
on  which is  exempt from  federal income  tax. "Municipal  Obligations" include
notes, bonds and other securities issued by or on behalf of states,  territories
and  possessions of the U.S.  and the District of  Columbia, and their political
subdivisions, agencies and instrumentalities, the interest on such  Obligations,
in  the  opinion of  counsel for  the issuer  or the  Portfolio, is  exempt from
federal income tax. See  the Statement of Additional  Information for a  further
description of Municipal Obligations.
 
   
    The Portfolio will only invest in Municipal Obligations that are "investment
grade securities." Investment grade securities are (i) bonds rated within one of
the  four highest rating categories of Moody's (Aaa,  Aa, A or Baa) or S&P (AAA,
AA, A or BBB); (ii) notes rated within one of the two highest rating  categories
of  Moody's (MIG1 or  MIG2) or one of  the two highest  rating categories of S&P
(SP-1 or SP-2); (iii) commercial paper rated P-1 or P-2 by Moody's or A-1 or A-2
by S&P; (iv) variable rate securities rated  VMIG1 or VMIG2 by Moody's; and  (v)
unrated  Municipal  Obligations  that  the Adviser  believes  are  of comparable
quality to securities in the foregoing  rating categories. See the Statement  of
Additional  Information for  a further  description of  these rating categories.
Bonds rated Baa by Moody's or BBB by S&P have speculative characteristics.
    
 
    Under normal market conditions,  the Portfolio will invest  at least 80%  of
its  net assets  in Municipal  Obligations (or  futures contracts  or options on
futures relating thereto), which at the time of investment are "investment grade
securities." This  policy is  fundamental and  may not  be changed  without  the
approval  of a  majority of  the Portfolio's  outstanding voting  securities. In
addition, under normal market  conditions, at least 65%  of the Portfolio's  net
assets will be invested in such Municipal Obligations having an initial maturity
of more than one year.
 
    Although  there are no maturity restrictions on the Municipal Obligations in
which the  Portfolio  invests, it  is  currently anticipated  that  the  average
maturity  of the Portfolio will  range between 7 and  20 years. The Adviser will
actively  manage  the  Portfolio,  and  adjust  the  average  maturity   thereof
(including  the use of  futures contracts and options  on futures), depending on
its assessment  of the  relative  yields available  on securities  of  different
maturities  and its  expectations of  future changes  in interest  rates. During
periods of rising interest rates and  declining prices, the average maturity  of
the  Portfolio may be shorter, while  during periods of declining interest rates
and rising prices, the Portfolio may have a longer average maturity.
 
    The Portfolio may  also invest up  to 20% of  its net assets  in cash,  cash
equivalents,  U.S. Government Securities and taxable corporate "investment grade
securities." U.S. Government  Securities consist  of direct  obligations of  the
U.S.   Treasury   and   securities   issued  or   guaranteed   by   agencies  or
instrumentalities of the  U.S. Government.  Securities issued  or guaranteed  by
agencies  or instrumentalities may be backed by the full faith and credit of the
United States (such  as securities  issued by the  Government National  Mortgage
Association), or supported by the issuing agency's right to borrow from the U.S.
Treasury  (such as Federal Home Loan Banks), or backed only by the credit of the
issuing instrumentality (e.g.,  the Federal National  Mortgage Association).  In
addition, for temporary defensive purposes, the Portfolio may invest part or all
of  its assets  in cash or  in short-term securities,  including certificates of
deposit, commercial paper, U.S. Government Securities and repurchase  agreements
involving  such government securities.  The Portfolio will  not invest more than
20% of its net assets in Municipal Obligations the interest on which is  subject
to alternative minimum tax.
 
                                       18
<PAGE>
    Any remaining assets of the Portfolio not invested as described above may be
invested  in  certain  securities or  obligations  as set  forth  in "Additional
Investment Information" below.
 
THE MORTGAGE-BACKED SECURITIES PORTFOLIO
 
    The Portfolio seeks  to produce  as high  a level  of current  income as  is
consistent   with   preservation   of  capital   by   investment   primarily  in
mortgage-backed  securities  either  (i)  issued  or  guaranteed  by  the   U.S.
Government  or  (ii)  rated  A or  higher  by  Moody's or  S&P,  or  if unrated,
determined by the Adviser to be of comparable quality.
 
    "Mortgage-backed securities" are  securities that,  directly or  indirectly,
represent a participation in, or are secured by and payable from, mortgage loans
on  real property, including governmental  pass-through securities such as those
issued or guaranteed by the  Government National Mortgage Association  ("GNMA"),
the  Federal National  Mortgage Association ("FNMA")  and the  Federal Home Loan
Mortgage  Corporation  ("FHLMC").  Unlike  GNMA  certificates,  FNMA  and  FHLMC
obligations  are not backed by the full faith and credit of the U.S. government;
they are supported  by the issuing  instrumentality's right to  borrow from  the
U.S.  Treasury. Each of GNMA, FNMA  and FHLMC guarantees timely distributions of
interest to  certificate  holders  and  GNMA  and  FNMA  also  guarantee  timely
distributions  of scheduled  principal. Mortgage-backed  securities also include
collateralized mortgage obligations ("CMOs") and pass-through securities  issued
or  guaranteed  by  private  sector  entities.  CMOs  are  debt  obligations  or
pass-through certificates issued  by agencies or  instrumentalities of the  U.S.
government  or by private  originators or investors in  mortgage loans. CMOs are
backed by mortgage pass-through securities or whole loans and are evidenced by a
series of bonds or certificates issued in multiple classes or tranches.  Private
pass-through  securities are  issued by private  originators of  or investors in
mortgage  loans  and  are  structured  similarly  to  governmental  pass-through
securities.  Because  private pass-throughs  typically  lack a  guarantee  by an
entity having the  credit status  of a governmental  agency or  instrumentality,
they  are generally structured with one or more types of credit enhancement. See
the  Statement  of   Additional  Information  for   a  further  description   of
Mortgage-Backed Securities.
 
    The Portfolio will only invest in mortgage-backed securities that are either
(i)  issued  or guaranteed  by the  U.S. Government  or one  of its  agencies or
instrumentalities or (ii)  at the  time of investment  rated within  one of  the
three highest rating categories of Moody's (Aaa, Aa or A) or S&P (AAA, AA or A),
or  if unrated,  determined by  the Adviser to  be of  comparable quality. Under
normal market  conditions,  the  Adviser  expects  that  at  least  75%  of  the
Portfolio's  net assets will be invested in mortgage-backed securities issued or
guaranteed by the U.S.  Government, its agencies  or instrumentalities or  rated
Aaa  by Moody's or AAA  by S&P. Up to  15% of the Portfolio's  net assets may be
invested in mortgage-backed securities rated A by Moody's or S&P.
 
    The  Adviser  expects  that  short-  and  intermediate-term  mortgage-backed
securities will form the core of the Portfolio, with long-term securities (i.e.,
with  maturities over ten years) being  purchased when the Adviser believes that
they will enhance return without significantly increasing risk. The Adviser sets
an annual target rate of return for the Portfolio based on current and projected
market and  economic  conditions and  manages  the Portfolio  conservatively  --
primarily  through gradual shifts in maturities -- in attempting to achieve this
target rate.
 
    The Portfolio may  also invest up  to 25% of  its net assets  in cash,  cash
equivalents  or other short-term securities,  including certificates of deposit,
commercial paper and  money market instruments,  U.S. Government securities  and
repurchase  agreements involving  such government  securities. In  addition, the
Portfolio may invest up to  all of its assets in  cash and such instruments  for
temporary defensive purposes.
 
                                       19
<PAGE>
    Any remaining assets of the Portfolio not invested as described above may be
invested  in  certain  securities or  obligations  as set  forth  in "Additional
Investment Information" below.
 
THE HIGH YIELD PORTFOLIO
 
    The Portfolio seeks to maximize total  return by investing in a  diversified
portfolio  of high yield fixed  income securities that offer  a yield above that
generally available on debt securities in the three highest rating categories of
the recognized rating services. The  Portfolio normally invests between 80%  and
100%  of its total  assets in these higher  yielding securities, which generally
entails increased credit and market risk. To mitigate these risks the  Portfolio
will  diversify  its  holdings  by  issuer,  industry  and  credit  quality, but
investors should  carefully  review the  section  below entitled  "Risk  Factors
Relating to Investing in High Yield Securities."
 
    Appendix A to this Prospectus sets forth a description of the corporate bond
rating categories of Moody's and S&P. Corporate bonds rated below Baa by Moody's
or  BBB  by S&P  are  considered speculative.  Securities  in the  lowest rating
categories may  have  predominantly speculative  characteristics  or may  be  in
default.  Ratings of S&P and Moody's represent  their opinions of the quality of
bonds and other debt securities they undertake to rate at the time of  issuance.
However,  ratings  are not  absolute standards  of quality  and may  not reflect
changes in an issuer's creditworthiness. Accordingly, although the Adviser  will
consider ratings, it will perform its own analysis and will not rely principally
on  ratings. The  Adviser will  consider, among other  things, the  price of the
security, and  the  financial  history  and condition,  the  prospects  and  the
management of an issuer in selecting securities for the Portfolio. The Portfolio
may  buy unrated  securities that the  Adviser believes are  comparable to rated
securities and are consistent with  the Portfolio's objective and policies.  The
Adviser may vary the average maturity of the securities in the Portfolio without
limit and there is no restriction on the maturity of any individual security.
 
    The  Portfolio may acquire fixed income  securities of both U.S. and foreign
issuers, including debt obligations  (e.g., bonds, debentures, notes,  equipment
lease  certificates, equipment trust  certificates, conditional sales contracts,
commercial paper and obligations  issued or guaranteed  by the U.S.  Government,
any  foreign government with which the  United States maintains relations or any
of their respective political  subdivisions, agencies or instrumentalities)  and
preferred  stock. The Portfolio may not invest  more than 5% of its total assets
at time of  acquisition in  either (1) equipment  lease certificates,  equipment
trust  certificates and conditional  sales contracts or  (2) limited partnership
interests. The Portfolio may neither invest more than 10% of its total assets in
foreign securities  nor invest  more than  5%  of its  total assets  in  foreign
governmental issuers in any one country. The Portfolio's fixed income securities
may  have  equity  features, such  as  conversion  rights or  warrants,  and the
Portfolio may invest up to  10% of its total  assets in equity securities  other
than preferred stock (common stocks, warrants and rights and limited partnership
interests).  The Portfolio  may invest up  to 20%  of its total  assets in fixed
income securities that are investment grade (i.e., rated in one of the top three
categories or comparable) and have maturities of one year or less. For temporary
defensive purposes, the Portfolio may invest part or all of its total assets  in
cash  or in short-term securities, including certificates of deposit, commercial
paper, notes, obligations issued or guaranteed by the U.S. Government or any  of
its  agencies  or instrumentalities,  and  repurchase agreements  involving such
government securities.  The  Portfolio  may  invest  in  or  own  securities  of
companies   in  various   stages  of  financial   restructuring,  bankruptcy  or
reorganization which are not currently  paying interest or dividends. The  total
value,  at time of purchase,  of the sum of all  such securities will not exceed
10% of the value of the Portfolio's total assets.
 
                                       20
<PAGE>
    The Portfolio  may  also invest  in  zero coupon,  pay-in-kind  or  deferred
payment  securities. Zero  coupon securities are  securities that are  sold at a
discount to par  value and securities  on which interest  payments are not  made
during  the  life of  the security.  Upon  maturity, the  holder is  entitled to
receive the par value of the security.  While interest payments are not made  on
such securities, holders of such securities are deemed to have received "phantom
income"  annually. Because the Portfolio will distribute its "phantom income" to
shareholders, to the extent that shareholders elect to receive dividends in cash
rather than reinvesting such dividends in additional shares of the Portfolio, it
will have fewer assets with which  to purchase income producing securities.  The
Portfolio  accrues income with respect to  these securities prior to the receipt
of cash  payments.  Pay-in-kind securities  are  securities that  have  interest
payable  by  delivery of  additional securities.  Upon  maturity, the  holder is
entitled to receive the aggregate par value of the securities. Deferred  payment
securities   are  securities  that   remain  zero  coupon   securities  until  a
predetermined date, at which time the  stated coupon rate becomes effective  and
interest  becomes  payable at  regular intervals.  Zero coupon,  pay-in-kind and
deferred payment securities may be subject  to greater fluctuation in value  and
lesser liquidity in the event of adverse market conditions than comparably rated
securities paying cash interest at regular interest payment periods.
 
    Any remaining assets of the Portfolio not invested as described above may be
invested  in  certain  securities or  obligations  as set  forth  in "Additional
Investment Information" below.
 
    RISK FACTORS RELATING TO INVESTING IN  HIGH YIELD SECURITIES.  Fixed  income
securities  are subject to the  risk of an issuer's  inability to meet principal
and interest payments on the obligations (credit risk), and may also be  subject
to  price volatility  due to such  factors as interest  rate sensitivity, market
perception of the creditworthiness  of the issuer  and general market  liquidity
(market  risk). Lower  rated or unrated  (i.e., high yield)  securities are more
likely to react to developments affecting  market and credit risk than are  more
highly  rated  securities, which  react  to movements  in  the general  level of
interest rates primarily. The market  values of fixed-income securities tend  to
vary  inversely with the  level of interest  rates. Yields and  market values of
high yield securities  will fluctuate  over time, reflecting  not only  changing
interest rates but the market's perception of credit quality and the outlook for
economic  growth. When economic conditions appear to be deteriorating, medium to
lower rated  securities may  decline in  value due  to heightened  concern  over
credit  quality, regardless  of prevailing  interest rates.  Fluctuations in the
value of the Portfolio's  investments will be reflected  in the Portfolio's  net
asset value per share. The Adviser considers both credit risk and market risk in
making  investment  decisions  for  the  Portfolio.  Investors  should carefully
consider the relative risks of investing in high yield securities and understand
that such securities are not generally meant for short-term investing.
 
    The high  yield  market  is  still relatively  new  and  its  recent  growth
parallels  a  long  period of  economic  expansion  and an  increase  in merger,
acquisition and  leveraged buyout  activity. Adverse  economic developments  may
disrupt the market for high yield securities, and severely affect the ability of
issuers,  especially highly leveraged issuers, to service their debt obligations
or to repay their obligations upon  maturity. In addition, the secondary  market
for  high  yield  securities, which  is  concentrated in  relatively  few market
makers, may not  be as  liquid as  the secondary  market for  more highly  rated
securities.  As a result, the Adviser could find it more difficult to sell these
securities or may be able  to sell the securities only  at prices lower than  if
such  securities were widely traded. Prices realized upon the sale of such lower
rated or unrated  securities, under these  circumstances, may be  less than  the
prices used in calculating the Portfolio's net asset value.
 
    Prices  for  high  yield  securities  may  be  affected  by  legislative and
regulatory developments. These laws could  adversely affect the Portfolio's  net
asset   value  and   investment  practices,   the  secondary   market  for  high
 
                                       21
<PAGE>
yield securities, the financial condition of issuers of these securities and the
value of outstanding  high yield  securities. For  example, federal  legislation
requiring  the divestiture by federally insured savings and loan associations of
their investments in high yield bonds and limiting the deductibility of interest
by certain corporate issuers of high  yield bonds adversely affected the  market
in recent years.
 
    Lower  rated or unrated debt obligations also present risks based on payment
expectations. If an issuer  calls the obligations for  redemption, the Fund  may
have  to replace  the security  with a lower  yielding security,  resulting in a
decreased return  for investors.  If the  Portfolio experiences  unexpected  net
redemptions,  it may be forced to sell its higher rated securities, resulting in
a decline in the overall credit quality of the Portfolio's investment  portfolio
and  increasing  the  exposure of  the  Portfolio  to the  risks  of  high yield
securities.
 
   
    The table  below provides  a summary  of  ratings assigned  by S&P  to  debt
obligations  in  the High  Yield  Portfolio. These  figures  are dollar-weighted
averages of month-end portfolio holdings  during the fiscal year ended  December
31,  1995, presented as a percentage of total investments. These percentages are
historical and  are not  necessarily indicative  of the  quality of  current  or
future portfolio holdings, which may vary.
    
 
   
<TABLE>
<CAPTION>
      S&P
- ----------------
RATING   AVERAGE
- -------  -------
<S>      <C>
A        0.21%
         -------
BBB      0.03%
         -------
BB       18.50%
         -------
B        47.27%
         -------
CCC      7.27%
         -------
CC       1.07%
         -------
Unrated  21.03%
         -------
</TABLE>
    
 
   
THE MONEY MARKET PORTFOLIO
    
 
    The  Portfolio's investment  objectives are  to maximize  current income and
preserve capital while maintaining high levels of liquidity through investing in
the following  high  quality  money  market  instruments  which  have  effective
maturities  of  one  year  or  less.  The  Portfolio's  average  maturity  (on a
dollar-weighted basis) will not exceed 90 days. The Portfolio will purchase only
securities having a  remaining maturity of  one year or  less. The Portfolio  is
expected  to maintain  a net  asset value of  $1.00 per  share. There  can be no
assurance, however, that the Portfolio will  be successful in maintaining a  net
asset value of $1.00 per share. See "Valuation of Shares."
 
    UNITED STATES GOVERNMENT OBLIGATIONS.  The Money Market Portfolio may invest
in  obligations issued  or guaranteed by  the United States  Government, such as
U.S. Treasury securities and those  backed by the full  faith and credit of  the
United  States, such as obligations of GNMA, the Farmers Home Administration and
the Export-Import Bank. The Portfolio may  also invest in obligations issued  or
guaranteed  by United States Government  agencies or instrumentalities where the
Portfolio must  look  principally to  the  issuing or  guaranteeing  agency  for
ultimate repayment; some examples of agencies or instrumentalities issuing these
obligations are the Federal Farm Credit System and the Federal Home Loan Banks.
 
                                       22
<PAGE>
    MORTGAGE-BACKED  SECURITIES.  Mortgage-backed securities  in which the Money
Market Portfolio may invest,  such as GNMA securities,  differ from other  fixed
income  securities in that the  principal is paid back  by the borrower over the
life of the loan rather than returned in a lump sum at maturity. When prevailing
interest rates rise, the value of a GNMA security may decrease as do other  debt
securities.  When prevailing interest rates decline,  however, the value of GNMA
securities may not rise on a comparable basis with other debt securities because
of  the  prepayment  feature  of  GNMA  securities.  Additionally,  if  a   GNMA
certificate  is purchased  at a  premium above  its principal  value because its
fixed rate of interest  exceeds the prevailing level  of yields, the decline  in
price  to par may  result in a loss  of the premium in  the event of prepayment.
Funds received from  prepayments may  be reinvested at  the prevailing  interest
rates  which may  be lower than  the rate  of interest that  had previously been
earned.
 
    BANK OBLIGATIONS.   The Money Market  Portfolio may invest  in high  quality
U.S.  dollar-denominated  negotiable  certificates  of  deposit,  time deposits,
deposit  notes  and  bankers'  acceptances  of  (i)  banks,  savings  and   loan
associations  and savings banks which have more  than $2 billion in total assets
and are  organized  under United  States  Federal  or state  law,  (ii)  foreign
branches  of these banks ("Euros")  and (iii) U.S. branches  of foreign banks of
equivalent size ("Yankees"). See "Additional Investment Information" for further
information on foreign investments. The Portfolio may also invest in obligations
of the International  Bank for  Reconstruction and  Development ("World  Bank").
These  obligations are supported  by appropriated but  unpaid commitments of the
World Bank's member countries, and there is no assurance these commitments  will
be undertaken or met in the future.
 
    COMMERCIAL PAPER; CORPORATE BONDS.  The Money Market Portfolio may invest in
high  quality commercial paper and corporate  bonds issued by U.S. corporations.
The Portfolio may also invest in commercial paper issued by foreign corporations
if the issuer is a  direct subsidiary of a  U.S. corporation, the obligation  is
U.S.  dollar-denominated and is not subject  to foreign withholding tax, and the
aggregate of these foreign  investments does not exceed  10% of the  Portfolio's
net  assets.  For more  information about  foreign investments,  see "Additional
Investment Information."
 
    QUALITY INFORMATION.  The Money Market Portfolio utilizes the amortized cost
method of valuation in accordance with regulations issued by the Securities  and
Exchange  Commission. See "Valuation of Shares." Accordingly, the Portfolio will
limit its portfolio investments to those instruments that present minimal credit
risks and  are of  "eligible quality"  as determined  by the  Adviser under  the
supervision  of the  Board of  Directors in  accordance with  regulations of the
Securities and Exchange Commission,  as they may from  time to time be  amended.
For  this purpose, "eligible quality"  means a security rated  (i) in one of the
two highest rating categories by at least two nationally recognized  statistical
rating  organizations assigning a rating  to the security or  issuer or, (ii) if
only one rating organization assigned a  rating, by that rating organization  or
(iii) if unrated, of comparable quality as determined by the Board of Directors.
Among the criteria adopted by the Board of Directors, the Money Market Portfolio
will  not purchase any bank or corporate  obligation unless it is rated at least
Aa or Prime-1  by Moody's or  AA or A-1  by S&P, or  it is unrated,  and in  the
determination  of the Board  of Directors and  the Adviser, it  is of comparable
quality. Ratings,  however,  are  not  the  only  criteria  utilized  under  the
procedures  adopted by the Board of Directors. For a more detailed discussion of
other quality  requirements applicable  to the  Portfolio, see  "Description  of
Securities and Ratings and Policies" in the Statement of Additional Information.
 
                                       23
<PAGE>
    These  standards must be satisfied at the time an investment is made. In the
event that an investment  held by the  Portfolio is assigned  a lower rating  or
ceases  to be rated, the Adviser under the supervision of the Board of Directors
will promptly reassess whether  such security presents  minimal credit risk  and
whether  the Portfolio should continue to hold the security in its portfolio. If
a portfolio security no  longer presents minimal credit  risk or is in  default,
the  Portfolio will  dispose of the  security as soon  as reasonably practicable
unless the  Board of  Directors determines  that to  do so  is not  in the  best
interests of the Portfolio.
 
    Any remaining assets of the Portfolio not invested as described above may be
invested  in  certain  securities or  obligations  as set  forth  in "Additional
Investment Information" below.
 
THE MUNICIPAL MONEY MARKET PORTFOLIO
 
    The Portfolio's investment objectives are to maximize current income that is
exempt from  federal income  tax  and preserve  capital while  maintaining  high
levels  of liquidity through  investing in the  following high quality municipal
money market instruments which, in the  opinion of bond counsel for the  issuer,
earn  interest exempt from federal income  tax. The Portfolio will purchase only
securities having  a  remaining maturity  of  one  year or  less.  Under  normal
circumstances,  the  Portfolio  will  invest  at  least  80%  of  its  assets in
tax-exempt municipal securities. Additionally,  the Portfolio will not  purchase
private  activity bonds, the  interest from which is  subject to the alternative
minimum tax. Interest on tax-exempt municipal securities may be subject to state
and  local  taxes.  See  "Taxes."   The  Portfolio's  average  maturity  (on   a
dollar-weighted  basis) will  not exceed 90  days. The Portfolio  is expected to
maintain a  net asset  value of  $1.00 per  share. There  can be  no  assurance,
however,  that the Portfolio will be successful in maintaining a net asset value
of $1.00 per share. See "Valuation of Shares."
 
    MUNICIPAL BONDS.  The Portfolio may invest  in bonds issued by or on  behalf
of   states,  territories  and  possessions  of   the  U.S.  and  its  political
subdivisions, agencies, authorities and instrumentalities. These obligations may
be general obligation bonds  secured by the issuer's  pledge of its full  faith,
credit  and taxing power for the payment  of principal and interest, or they may
be revenue bonds payable from specific revenue sources, but not generally backed
by the issuer's taxing power.  These obligations include private activity  bonds
where  payment  is the  responsibility  of the  private  industrial user  of the
facility financed by the bonds.  The Portfolio may invest  more than 25% of  its
total assets in private activity bonds (provided that the interest on such bonds
is not subject to the alternative minimum tax), but may not invest more than 25%
of  its total assets in these  bonds in projects of similar  type or in the same
state.
 
    MUNICIPAL NOTES.   The  Portfolio  may also  invest  in municipal  notes  of
various  types, including notes issued in  anticipation of receipt of taxes, the
proceeds of the  sale of  bonds, other revenues  or grant  proceeds and  project
notes,  as well as municipal commercial  paper and municipal demand obligations.
There may be no secondary market for  project notes, and it is the intention  of
the  Fund to  hold such  notes until maturity.  There is  no specific percentage
limitation on these investments. For more information about municipal notes, see
"Description  of  Securities  and  Ratings"  in  the  Statement  of   Additional
Information.
 
    QUALITY  INFORMATION.  The  Portfolio utilizes the  amortized cost method of
valuation in accordance with regulations  issued by the Securities and  Exchange
Commission. See "Valuation of Shares." Accordingly, the Portfolio will limit its
portfolio investments to those instruments which present minimal credit risk and
which  are  of  "eligible  quality"  as  determined  by  the  Adviser  under the
supervision of the  Board of  Directors in  accordance with  regulations of  the
Securities  and Exchange Commission, as  they may from time  to time be amended.
For this purpose, "eligible quality"  means a security rated  (i) in one of  the
two highest rating
 
                                       24
<PAGE>
categories   by   at  least   two   nationally  recognized   statistical  rating
organizations assigning a rating to the security or issuer or, (ii) if only  one
rating  organization assigned a rating, by  that rating organization or (iii) if
unrated, of comparable quality  as determined by the  Board of Directors.  Among
the  criteria  adopted by  the Board  of Directors,  the Municipal  Money Market
Portfolio will not purchase any municipal obligation unless it is rated at least
Aa, MIG-1 (or MIG-2 in the case  of New York State municipal notes), or  Prime-1
by  Moody's,  or  AA,  SP-1  or  A-1  by S&P,  or  it  is  unrated,  and  in the
determination of the  Board of  Directors and the  Adviser it  is of  comparable
quality.  Ratings, however,  are not  the only  criteria which  must be utilized
under the procedures  adopted by  the Board of  Directors. For  a more  detailed
discussion  of quality requirements applicable to municipal commercial paper and
master demand obligations, see  the "Description of  Securities and Ratings"  in
the Statement of Additional Information.
 
    These  standards must be satisfied at the time an investment is made. In the
event that an investment  held by the  Portfolio is assigned  a lower rating  or
ceases  to be rated, the Adviser under the supervision of the Board of Directors
will promptly reassess whether  such security presents  minimal credit risk  and
whether  the Portfolio should continue to hold the security in its portfolio. If
a portfolio security no  longer presents minimal credit  risk or is in  default,
the  Portfolio will  dispose of the  security as soon  as reasonably practicable
unless the  Board of  Directors determines  that to  do so  is not  in the  best
interests  of  the Portfolio.  The credit  quality  of municipal  obligations is
frequently enhanced by various arrangements  with domestic or foreign  financial
institutions,  such as  letters of credit,  guarantees and  insurance, and these
arrangements are considered when investment quality is evaluated.
 
    PUTS FOR THE MUNICIPAL MONEY MARKET  PORTFOLIO.  The Portfolio may  purchase
without limit municipal bonds or notes together with the right to resell them at
an agreed price or yield within a specified period prior to maturity. This right
to resell is known as a "put". The aggregate price paid for securities with puts
may  be higher than the price which otherwise would be paid. The purpose of this
practice is  to  permit  the  Portfolio  to  be  fully  invested  in  tax-exempt
securities while maintaining the necessary liquidity to purchase securities on a
when-issued  basis, to meet unusually large  redemptions, to purchase at a later
date securities  other than  those subject  to  the put  and to  facilitate  the
Adviser's  ability to manage the Portfolio  actively. The principal risk of puts
is that the put writer may default on its obligation to repurchase. The  Adviser
will monitor each writer's ability to meet its obligations under puts. Under the
supervision of the Board of Directors, the Adviser will purchase securities with
puts  only to the extent  that such purchase is  consistent with the Portfolio's
investment policies.
 
    The amortized cost method  is used by the  Portfolio to value all  municipal
securities;  no value  is assigned  to any  puts. The  cost of  any such  put is
carried as an unrealized loss from the time of purchase until it is exercised or
expires.
 
    Any remaining assets of the Portfolio not invested as described above may be
invested in  certain  securities or  obligations  as set  forth  in  "Additional
Investment Information" below.
 
                                       25
<PAGE>
                       ADDITIONAL INVESTMENT INFORMATION
 
    FOREIGN  INVESTMENT.  The Fixed Income  and High Yield Portfolios may invest
in U.S. dollar-denominated securities of foreign issuers trading in U.S. markets
and in non-U.S.  dollar-denominated obligations  of foreign  issuers. The  Money
Market  Portfolio may invest in  U.S. dollar-denominated commercial paper issued
by a  foreign corporation  that  is a  direct parent  or  subsidiary of  a  U.S.
corporation.  Investment  in  obligations  of  foreign  issuers  and  in foreign
branches of domestic  banks involves  somewhat different  investment risks  than
those  affecting  obligations of  U.S. issuers.  There  may be  limited publicly
available information with respect to  foreign issuers, and foreign issuers  are
not  generally subject to  uniform accounting, auditing  and financial standards
and requirements comparable to those applicable to domestic companies. Brokerage
commissions and  other transaction  costs on  foreign securities  exchanges  are
generally higher than in the U.S. Dividends and interest paid by foreign issuers
may  be subject to withholding  and other foreign taxes,  which may decrease the
net return on foreign investments as compared to dividends and interest paid  to
the  Portfolio by domestic companies. It is not expected that a Portfolio or its
shareholders would be able to claim a credit for U.S. tax purposes with  respect
to  any  such  foreign  taxes.  See  "Taxes."  Additional  risks  include future
political and economic developments, the possibility that a foreign jurisdiction
might impose  or change  withholding taxes  on income  payable with  respect  to
foreign  securities, possible  seizure, nationalization or  expropriation of the
foreign issuer  or  foreign  deposits,  and the  possible  adoption  of  foreign
governmental  restrictions  such  as  exchange  controls.  Many  of  the foreign
countries described above may have less stable political environments than  more
developed  countries. Also, it may  be more difficult to  obtain a judgment in a
court outside the United States.
 
   
    Investments in securities of foreign  issuers are frequently denominated  in
foreign  currencies and the Portfolios  may temporarily hold uninvested reserves
in bank deposits in foreign currencies. Therefore, the value of each Portfolio's
assets as measured in U.S. dollars  may be affected favorably or unfavorably  by
changes  in  currency  rates  and  in  exchange  control  regulations,  and  the
Portfolios may  incur  costs  in connection  with  conversions  between  various
currencies.
    
 
    FORWARD FOREIGN CURRENCY EXCHANGE CONTRACTS.  The Fixed Income, Global Fixed
Income  and  High  Yield  Portfolios may  enter  into  forward  foreign currency
exchange contracts ("forward contracts") that  provide for the purchase or  sale
of  an amount of a specified currency at  a future date. Purposes for which such
contracts may be used include protecting against a decline in a foreign currency
against the U.S.  dollar between  the trade date  and settlement  date when  the
Portfolio  purchases or  sells securities, locking  in the U.S.  dollar value of
dividends and  interest  on  securities  held by  the  Portfolio  and  generally
protecting  the U.S.  dollar value  of securities  held by  a Portfolio declared
against exchange  rate  fluctuation.  Such  contracts may  also  be  used  as  a
protective measure against the effects of fluctuating rates of currency exchange
and  exchange control regulations. While such forward contracts may limit losses
to a portfolio as a result of  exchange rate fluctuations, they will also  limit
any  gains that may otherwise have been realized. See "Investment Objectives and
Policies -- Forward Currency Exchange Contracts" in the Statement of  Additional
Information.  Except in circumstances where segregated accounts are not required
by the 1940 Act and the rules adopted thereunder, the Portfolio's Custodian will
place cash, U.S.  government securities,  or high-grade debt  securities into  a
segregated  account  of a  Portfolio in  an amount  equal to  the value  of such
Portfolio's total  assets  committed  to the  consummation  of  forward  foreign
currency  exchange  contracts. If  the  value of  the  securities placed  in the
segregated account declines, additional cash or securities will be placed in the
account on a daily basis so that the value of the
 
                                       26
<PAGE>
account will be  at least equal  to the amount  of such Portfolio's  commitments
with  respect  to such  contracts. See  "Investment  Objectives and  Policies --
Forward Foreign  Currency Exchange  Contracts" in  the Statement  of  Additional
Information.
 
    FUTURES  CONTRACTS AND  OPTIONS ON  FUTURES CONTRACTS.   In  order to remain
fully invested  and to  reduce  transaction costs,  each Portfolio,  except  the
Global  Fixed Income Portfolio, may  utilize appropriate stock futures contracts
and options on futures contracts to a limited extent. Because transaction  costs
associated  with futures and options may be lower than the costs of investing in
stocks directly, it is  expected that the  use of index  futures and options  to
facilitate  cash flows may  reduce a Portfolio's  overall transaction costs. The
Portfolios will engage in futures and  options on futures transactions only  for
hedging purposes.
 
    Each  Portfolio  may enter  into futures  contracts  and options  on futures
provided that not more than  5% of its total assets  are required as deposit  to
secure obligations under such contracts, and provided further that not more than
20% of its total assets are invested, in the aggregate, in futures contracts and
options on futures.
 
    The  primary risks associated with the use of futures and options on futures
are (i) imperfect correlation between the  change in market value of the  stocks
held  by the  Portfolio and the  prices of  futures and options  relating to the
stocks purchased or sold by  the Portfolio; and (ii)  possible lack of a  liquid
secondary  market for a futures contract and  the resulting inability to close a
futures position which could have an  adverse impact on the Portfolio's  ability
to  hedge. In the opinion of the Board of Directors, the risk that the Portfolio
will be unable  to close  out a  futures position  or options  contract will  be
minimized  by only entering  into futures contracts  or options transactions for
which there  appears  to  be  a  liquid  secondary  market.  For  more  detailed
information about futures transactions, see "Investment Objectives and Policies"
in the Statement of Additional Information.
 
    LOANS  OF PORTFOLIO SECURITIES.   Each Portfolio may  lend its securities to
brokers, dealers, domestic and foreign banks or other financial institutions for
the purpose of increasing its net investment income. These loans must be secured
continuously by cash or equivalent collateral or by a letter of credit at  least
equal  to the  market value  of the securities  loaned plus  accrued interest or
income. There may be risks of delay  in recovery of the securities or even  loss
of  rights  in  the  collateral  should  the  borrower  of  the  securities fail
financially. A  Portfolio  will  not enter  into  securities  loan  transactions
exceeding,  in the  aggregate, 33  1/3% of the  market value  of the Portfolio's
total assets.  For  more  detailed  information  about  securities  lending  see
"Investment Objectives and Policies" in the Statement of Additional Information.
 
    MONEY  MARKET INSTRUMENTS.  The Portfolios  are permitted to invest in money
market  instruments,  although  each  Portfolio  intends  to  stay  invested  in
securities  satisfying its primary investment objective to the extent practical.
Each Portfolio may  make money  market investments pending  other investment  or
settlement  for liquidity,  or in  adverse market  conditions. The  money market
investments permitted  for  the  Portfolios  include  obligations  of  the  U.S.
Government  and  its  agencies  and  instrumentalities,  obligations  of foreign
sovereignties,  other   debt  securities,   commercial  paper   including   bank
obligations,  certificates  of  deposit  (including  Eurodollar  certificates of
deposit) and repurchase  agreements. For more  detailed information about  these
money  market investments,  see "Description of  Securities and  Ratings" in the
Statement of Additional Information.
 
    NON-PUBLICLY  TRADED   SECURITIES,   PRIVATE   PLACEMENTS   AND   RESTRICTED
SECURITIES.   The High-Yield Portfolio  may not invest more  than 15% of its net
assets in  illiquid  securities, including  securities  for which  there  is  no
readily  available securities market  nor more than  10% of its  total assets in
securities that are restricted from sale
 
                                       27
<PAGE>
to  the  public  without   registration  ("Restricted  Securities")  under   the
Securities  Act of 1933 (the "1933 Act"). Nevertheless, subject to the foregoing
limit on illiquid securities, the  Portfolio may invest up  to 20% of its  total
assets  in  Restricted Securities  that  can be  offered  and sold  to qualified
institutional buyers under  Rule 144A  under that Act  ("144A Securities").  The
Board  of Directors has adopted guidelines and delegated to the Adviser, subject
to the supervision of the Board of Directors, the daily function of  determining
and monitoring the liquidity of 144A securities. Rule 144A securities may become
illiquid  if qualified institutional buyers are  not interested in acquiring the
securities. Investors  should note  that  investments in  excess  of 5%  of  the
Portfolio's  total  assets  may be  considered  a speculative  activity  and may
involve greater risk and expense to the Portfolio.
 
    REPURCHASE AGREEMENTS.  Each Portfolio may enter into repurchase  agreements
with  brokers, dealers or  banks that meet  the credit guidelines  of the Fund's
Board of Directors. In a repurchase agreement, a Portfolio buys a security  from
a  seller that has  agreed to repurchase it  at a mutually  agreed upon date and
price, reflecting the interest rate effective for the term of the agreement. The
term of these agreements is usually from overnight to one week and never exceeds
one year. Repurchase agreements may be viewed as a fully collateralized loan  of
money  by the Portfolio to the  seller. The Portfolio always receives securities
with a market  value at  least equal to  the purchase  price (including  accrued
interest)  as collateral, and  this value is  maintained during the  term of the
agreement. If  the  seller  defaults  and the  collateral  value  declines,  the
Portfolio  might  incur a  loss. If  bankruptcy  proceedings are  commenced with
respect to the seller,  the Portfolio's realization upon  the collateral may  be
delayed  or limited. The aggregate of  certain repurchase agreements and certain
other investments is limited as set forth under "Investment Limitations."
 
    REVERSE REPURCHASE AGREEMENTS  FOR THE  MONEY MARKET PORTFOLIO.   The  Money
Market  Portfolio  may enter  into reverse  repurchase agreements  with brokers,
dealers, domestic  and  foreign banks  or  other financial  institutions.  In  a
reverse  repurchase  agreement, the  Portfolio sells  a  security and  agrees to
repurchase it at a mutually agreed upon date and price, reflecting the  interest
rate  effective for  the term  of the agreement.  It may  also be  viewed as the
borrowing of money by the Portfolio. The Portfolio's investment of the  proceeds
of  a reverse repurchase agreement is  the speculative factor known as leverage.
The Portfolio may enter into a reverse repurchase agreement only if the interest
income from investment of the proceeds  is greater than the interest expense  of
the  transaction and the proceeds  are invested for a  period no longer than the
term of the agreement. The Portfolio will maintain with the Custodian a separate
account with a segregated portfolio of securities at least equal to its purchase
obligations under  these agreements.  If interest  rates rise  during a  reverse
repurchase  agreement,  it  may  adversely  affect  the  Portfolio's  ability to
maintain a stable net asset value. The aggregate of these agreements is  limited
as  set forth under "Investment  Limitations." Reverse repurchase agreements are
considered to be  borrowings and are  subject to the  percentage limitations  on
borrowings set forth in "Investment Limitations."
 
    TAXABLE  INVESTMENTS  FOR  THE  MUNICIPAL BOND  AND  MUNICIPAL  MONEY MARKET
PORTFOLIOS.  The Municipal Bond and Municipal Money Market Portfolios attempt to
invest 80%  and 100%,  respectively,  of their  assets in  tax-exempt  municipal
securities.  However, the Portfolios  are permitted to  invest up to  20% of the
value of  their total  assets in  securities, the  interest income  of which  is
subject  to federal  income tax. Either  Portfolio may  make taxable investments
pending investment of proceeds from sales of its shares or portfolio  securities
or  pending settlement of purchases of portfolio securities in order to maintain
liquidity to meet redemptions or when  it is advisable in the Adviser's  opinion
because  of  adverse market  conditions. The  taxable investments  permitted for
 
                                       28
<PAGE>
either Portfolio include obligations of the U.S. Government and its agencies and
instrumentalities, bank obligations, commercial paper and repurchase agreements.
Fees from loans  of tax-exempt  securities will also  be taxable  income of  the
Portfolio. See "Taxes."
 
    WHEN-ISSUED  AND DELAYED DELIVERY  SECURITIES.  Each  Portfolio may purchase
securities on a  when-issued or  delayed delivery basis.  In such  transactions,
instruments  are bought with payment and delivery  taking place in the future in
order to secure what is considered to  be an advantageous yield or price at  the
time  of the transaction. Delivery of and  payment for these securities may take
as long as a month  or more after the date  of the purchase commitment but  will
take  place no  more than  120 days  after the  trade date.  Each Portfolio will
maintain with the Custodian  a separate account with  a segregated portfolio  of
high-grade  debt  securities  or cash  in  an  amount at  least  equal  to these
commitments. The payment obligation and the interest rates that will be received
are each  fixed at  the  time a  Portfolio enters  into  the commitment  and  no
interest  accrues to the  Portfolio until settlement. Thus,  it is possible that
the market value at  the time of  settlement could be higher  or lower than  the
purchase  price if  the general  level of  interest rates  has changed.  It is a
fundamental policy of  the Money Market  Portfolio and a  current policy of  the
Municipal  Money  Market Portfolio  not  to enter  into  when-issued commitments
exceeding, in the aggregate,  15% of the market  value of the Portfolio's  total
assets less liabilities other than the obligations created by these commitments.
 
                             INVESTMENT LIMITATIONS
 
    As a diversified investment company, each Portfolio, except the Global Fixed
Income  Portfolio, is subject to the following limitations: (a) as to 75% of its
total assets, a Portfolio may not invest more than 5% of its total assets in the
securities of any one issuer, except obligations of the U.S. Government and  its
agencies and instrumentalities, and (b) a Portfolio may not own more than 10% of
the outstanding voting securities of any one issuer.
 
    The  Global Fixed Income  Portfolio is a  non-diversified investment company
under the Investment  Company Act of  1940, as amended  (the "1940 Act"),  which
means  the Global Fixed Income  Portfolio is not limited by  the 1940 Act in the
proportion of its  total assets that  may be  invested in the  obligations of  a
single  issuer. Thus,  the Global  Fixed Income  Portfolio may  invest a greater
proportion of its total assets in the securities of a smaller number of  issuers
and,  as a result, will be subject to greater risk with respect to its portfolio
securities. The Global Fixed Income  Portfolio, however, intends to comply  with
the  diversification requirements imposed by the  Internal Revenue Code of 1986,
as amended (the "Code"),  for qualification as  a regulated investment  company.
See "Taxes."
 
   
    Each  Portfolio also operates under certain investment restrictions that are
deemed fundamental limitations and may be changed only with the approval of  the
holders  of a majority  of such Portfolio's  outstanding shares. See "Investment
Limitations" in  the  Statement of  Additional  Information. In  addition,  each
Portfolio  operates  under  certain  non-fundamental  investment  limitations as
described below and in the  Statement of Additional Information. Each  Portfolio
may  not  (i) enter  into repurchase  agreements  with more  than seven  days to
maturity if, as a result, more than  15% of the market value of the  Portfolio's
net assets would be invested in such repurchase agreements and other investments
for  which market  quotations are not  readily available or  which are otherwise
illiquid, except  that the  limitation  is 5%  for  the Municipal  Money  Market
Portfolio;  (ii) borrow money, except from  banks for extraordinary or emergency
purposes, and then only in amounts up to 10% (which includes reverse  repurchase
agreements)  of the value of the Portfolio's  total assets, taken at cost at the
time of  borrowing; or  purchase securities  while borrowings  exceed 5%  (which
includes reverse repurchase agreements)
    
 
                                       29
<PAGE>
of  its total assets; (iii) or mortgage, pledge or hypothecate any assets except
in connection with any such borrowing in amounts  up to 10% of the value of  the
Portfolio's  net assets  at the  time of  borrowing; (iv)  invest in  fixed time
deposits with a duration  of over seven  calendar days; or  (v) invest in  fixed
time  deposits with a duration of from  two business days to seven calendar days
if more than  5% of  the Portfolio's  total assets  would be  invested in  these
deposits.  Furthermore, the  Money Market Portfolio  may not  enter into reverse
repurchase agreements exceeding, in the aggregate, one-third of the market value
of the Portfolio's total assets, less liabilities other than obligations created
by these agreements; and the Municipal  Money Market Portfolio may not  purchase
private  activity bonds if, as  a result, more than  5% of the Portfolio's total
assets would be invested  in private activity bonds  where payment of  principal
and  interest are the responsibility of companies with fewer than three years of
operating history (including predecessors).
 
                             MANAGEMENT OF THE FUND
 
    INVESTMENT ADVISER.  Morgan Stanley Asset Management Inc. is the  Investment
Adviser  and Administrator of the  Fund and each of  its portfolios. The Adviser
provides investment  advice and  portfolio management  services pursuant  to  an
Investment  Advisory Agreement  and, subject  to the  supervision of  the Fund's
Board of  Directors,  makes  the portfolio's  day-to-day  investment  decisions,
arranges  for the execution of portfolio  transactions and generally manages the
portfolio's investments. The Adviser is entitled to receive from each  Portfolio
an  annual management fee, payable quarterly, equal to the percentage of average
daily net  assets of  the respective  Portfolio set  forth in  the table  below.
However,  the Adviser  has agreed to  a reduction in  the fees payable  to it as
Adviser, and to reimburse the Portfolios, if necessary, if such fees would cause
the total annual operating expenses of  any Portfolio to exceed the maximum  set
forth in the table below.
 
<TABLE>
<CAPTION>
                                                                       MAXIMUM TOTAL OPERATING EXPENSES
                                                                              AFTER FEE WAIVERS
                                                MANAGEMENT FEE     ----------------------------------------
PORTFOLIO                                     ABSENT FEE WAIVERS         CLASS A              CLASS B
- --------------------------------------------  -------------------  -------------------  -------------------
<S>                                           <C>                  <C>                  <C>
Fixed Income                                           0.35%                0.45%                0.70%
Global Fixed Income                                    0.40%                0.50%                0.75%
Municipal Bond                                         0.35%                0.45%                0.70%
Mortgage-Backed Securities                             0.35%                0.45%                0.70%
High Yield                                             0.50%                0.75%                1.00%
Money Market                                           0.30%                0.55%               N/A
Municipal Money Market                                 0.30%                0.57%               N/A
</TABLE>
 
   
    The  Adviser, with  principal offices  at 1221  Avenue of  the Americas, New
York, New  York  10020,  conducts a  worldwide  portfolio  management  business,
providing  a broad  range of portfolio  management services to  customers in the
U.S. and abroad. At December 31, 1995, the Adviser, together with its affiliated
asset management  companies, managed  investments totaling  approximately  $57.4
billion, including approximately $41.9 billion under active management and $15.5
billion as Named Fiduciary or Fiduciary Adviser. See "Management of the Fund" in
the Statement of Additional Information.
    
 
                                       30
<PAGE>
    PORTFOLIO  MANAGERS.  The following  persons have primary responsibility for
managing the Portfolios indicated.
 
   
    FIXED INCOME  PORTFOLIO   --   WARREN ACKERMAN,  III. Warren  Ackerman is  a
Principal  of  the Advisor  and  a Senior  Fixed  Income Portfolio  Manager. Mr.
Ackerman joined the Advisor in December 1993. Prior to joining the Advisor,  Mr.
Ackerman  spent over 14 years with Bankers  Trust Company as a Managing Director
responsible for institutional active fixed income management. Prior to  Bankers,
he spent almost seven years as a Vice President with Irving Trust Company in the
Trust Investment Division. Mr. Ackerman is a graduate of Monmouth College with a
B.S.  in Economics. Mr. Ackerman has had primary responsibility for managing the
Portfolio's assets since March 1994.
    
 
   
    GLOBAL FIXED INCOME PORTFOLIO   --   MICHAEL J. SMITH  AND ROBERT M.  SMITH.
Michael  Smith joined the Adviser  as a Fixed Income  Manager in 1990. Mr. Smith
became a  Vice  President of  Morgan  Stanley in  1992  and has  been  primarily
responsible  for  managing the  Portfolio's assets  since  January 1993.  He was
previously employed by  Gartmore Investment Management  where he had  day-to-day
responsibility  for the management of global and European fixed-income and money
market funds. Prior to his three years  at Gartmore, Mr. Smith spent four  years
with  Legal & General Investment as an  analyst and fund manager responsible for
the fixed-income  portion of  several large  segregated funds.  Mr. Smith  is  a
graduate  of Exeter University, England. Robert Smith joined the Adviser as Vice
President in  June 1994  and has  been primarily  responsible for  managing  the
Portfolio's  assets since July 1994. Prior to joining the Adviser he spent eight
years as  Senior Portfolio  Manager --  Fixed  Income at  the State  of  Florida
Pension  Fund. Mr. Smith's responsibilities included active total-rate-of-return
management of  long  term  portfolios  and supervision  of  other  fixed  income
managers.  A graduate of Florida  State University with a  B.S. in Business, Mr.
Smith also  received  an  M.B.A. --  Finance  from  Florida State  and  holds  a
Chartered Financial Analyst (CFA) designation.
    
 
    MUNICIPAL  BOND PORTFOLIO   --   LORI A.  COHANE. Lori A.  Cohane joined the
Adviser in 1994 as a Vice President and Municipal Bond Portfolio Manager.  Prior
to joining the Adviser, Ms. Cohane spent eight years with Salomon Brothers Asset
Management  as a Vice President, Portfolio  Manager and Senior Credit Analyst of
municipal bond  accounts managing  portfolios for  high net  worth  individuals,
open-  and closed-end  bond funds  and institutional  accounts. Ms.  Cohane is a
magna cum laude graduate of  the State University of New  York at Albany with  a
B.S.  degree in Finance and Economics. Ms. Cohane has had primary responsibility
for managing the Portfolio's assets since its inception.
 
    MORTGAGE-BACKED SECURITIES PORTFOLIO  --  WARREN ACKERMAN, III.  Information
about  Mr. Ackerman is included under Fixed Income Portfolio above. Mr. Ackerman
has had primary  responsibility for  managing the Portfolio's  assets since  its
inception.
 
    HIGH YIELD PORTFOLIO  --  ROBERT ANGEVINE. Robert Angevine is a Principal of
the  Adviser  and the  Portfolio Manager  for high  yield investments.  Prior to
joining the Adviser  in October 1988,  he spent over  eight years at  Prudential
Insurance  where he was  responsible for the largest  open-end high yield mutual
fund in the country. Mr. Angevine also manages high yield assets for one of  the
largest  corporate pension funds  in the country.  His other experience includes
international  treasury  operations  at  a  major  pharmaceutical  company   and
commercial  banking. Mr.  Angevine received  an M.B.A.  from Fairleigh Dickinson
University and a B.A. in Economics  from Lafayette College. He served two  years
as  a Lieutenant in the  U.S. Army. Mr. Angevine  has had primary responsibility
for managing the Portfolio's assets since September, 1992.
 
                                       31
<PAGE>
   
    MONEY MARKET PORTFOLIO  --  GERALD BARTH, ABIGAIL JONES FEDER AND KENNETH R.
HOLLEY. Gerald P. Barth joined  the Adviser in 1987  to establish the short-  to
intermediate-term  taxable  cash management  area and  to manage  the tax-exempt
municipal bond portfolio. He became a Vice President in 1989 and a Principal  in
1991. He has had primary management responsibility for the Investment Fund since
its  inception.  Prior  to  joining  the  Adviser,  Mr.  Barth  was  Director of
Investments at  Subaru of  America for  five years,  where he  managed both  the
short-  and intermediate-term corporate cash portfolios.  He began his career at
Arthur Andersen  in  the  audit  department  and spent  two  years  in  the  tax
department.  He earned a  B.S. in Accounting  from LaSalle College  and became a
Certified Public  Accountant  in 1977.  Abigail  Feder  is a  Principal  in  the
Adviser's Fixed Income Group. She is responsible for managing short-term taxable
and  tax-exempt portfolios. Ms. Feder  joined Morgan Stanley's Corporate Finance
Department in 1985. In 1987  she joined the Adviser  as a Marketing Analyst  and
was  promoted to a Marketing Director in 1988. She joined the Fixed Income Group
as a Portfolio  Manager in 1989  and she became  a Vice President  in 1992.  Ms.
Feder  holds a B.A. from Vassar College. Kenneth R. Holley joined the Adviser as
a short-term fixed  income portfolio manager  in July, 1993.  Prior thereto,  he
worked  for 2 1/2  years as a  Finance Officer for  the African Development Bank
implementing trading strategies for the bank's $1 billion short to  intermediate
U.S.  dollar portfolio. Prior to  joining the ADB, Mr.  Holley spent 1 1/2 years
with Ward and Associates  Asset Management as a  Vice President responsible  for
fixed  income strategy. Before Ward and Associates he worked in the fixed income
department of  Salomon  Brothers,  Inc.  Mr.  Holley  holds  a  B.S.  degree  in
Engineering  from  University of  Pennsylvania and  an  M.B.A. from  the Wharton
School. Mr. Barth and Ms. Feder have had primary responsibility for managing the
Portfolio's assets since inception. Mr. Holley has shared primary responsibility
for managing the Portfolio's assets since August, 1993.
    
 
    MUNICIPAL MONEY MARKET  PORTFOLIO   --  GERALD  P. BARTH  AND ABIGAIL  JONES
FEDER.  Information about Mr. Barth and Ms. Feder is included under Money Market
Bond Portfolio above. Mr. Barth and Ms. Feder have shared primary responsibility
for managing the Portfolio's assets since inception.
 
    ADMINISTRATOR.   The  Adviser also  provides  the Fund  with  administrative
services  pursuant to an  Administration Agreement. The  services provided under
the Administration Agreement are subject to the supervision of the Officers  and
the  Board of  Directors of the  Fund, and include  day-to-day administration of
matters related  to the  corporate existence  of the  Fund, maintenance  of  its
records, preparation of reports, supervision of the Fund's arrangements with its
custodian,  and  assistance  in  the  preparation  of  the  Fund's  registration
statements under  Federal  and State  laws.  The Administration  Agreement  also
provides  that the Administrator  through its agents will  provide the Fund with
dividend disbursing  and transfer  agent services.  For its  services under  the
Administration  Agreement, the Fund pays  the Adviser a monthly  fee which on an
annual basis equals .15% of the average daily net assets of each Portfolio.
 
   
    Under an agreement between  the Adviser and The  Chase Manhattan Bank,  N.A.
("Chase"),  Chase provides  certain administrative  services to  the Fund.  In a
merger completed on September 1, 1995, Chase succeeded to all of the rights  and
obligations  under the U.S.  Trust Administration Agreement  between the Adviser
and the United  States Trust  Company of New  York ("U.S.  Trust"), pursuant  to
which  U.S. Trust had  agreed to provide certain  administrative services to the
Fund.  Pursuant  to  a  delegation  clause  in  the  U.S.  Trust  Administration
Agreement,  U.S. Trust  delegated its  administration responsibilities  to Chase
Global Funds Services Company ("CGFSC"), formerly known as Mutual Funds  Service
Company,  which after the  merger with Chase  is a subsidiary  of Chase and will
continue to provide  certain administrative  services to the  Fund. The  Adviser
supervises  and  monitors such  administrative services  provided by  CGFSC. The
services provided under the
    
 
                                       32
<PAGE>
Administration Agreement and  the U.S. Trust  Administration Agreement are  also
subject  to the supervision of the Board of  Directors of the Fund. The Board of
Directors of the  Fund has approved  the provision of  services described  above
pursuant  to  the Administration  Agreement  and the  U.S.  Trust Administration
Agreement as being in the best  interests of the Fund. CGFSC's business  address
is   73  Tremont  Street,  Boston,   Massachusetts  02108-3913.  For  additional
information  regarding   the  Administration   Agreement  or   the  U.S.   Trust
Administration  Agreement,  see "Management  of the  Fund"  in the  Statement of
Additional Information.
 
    DIRECTORS AND OFFICERS.  Pursuant  to the Fund's Articles of  Incorporation,
the  Board of Directors decides  upon matters of general  policy and reviews the
actions of the Fund's  Adviser, Administrator and  Distributor. The Officers  of
the Fund conduct and supervise its daily business operations.
 
    DISTRIBUTOR.   Morgan  Stanley serves  as the  exclusive Distributor  of the
shares of  the Fund.  Under its  Distribution Agreement  with the  Fund,  Morgan
Stanley  sells  shares of  each  Portfolio upon  the  terms and  at  the current
offering price described in this Prospectus. Morgan Stanley is not obligated  to
sell any certain number of shares of any Portfolio.
 
    The  Portfolios currently offer  only the classes of  shares offered by this
Prospectus. The Portfolios may in the future offer one or more classes of shares
with features, distribution expenses or  other expenses that are different  from
those of the classes currently offered.
 
    The  Fund has  adopted a Plan  of Distribution  with respect to  the Class B
shares of each of the Non-Money Portfolios pursuant to Rule 12b-1 under the 1940
Act (each, a "Plan").  Under each Plan, the  Distributor is entitled to  receive
from each of the Non-Money Portfolios a distribution fee, which is accrued daily
and  paid quarterly, of 0.25% of the Class B shares' average daily net assets on
an annualized basis. The  Distributor expects to reallocate  most of its fee  to
its   investment  representatives.  The  Distributor  may,  in  its  discretion,
voluntarily waive from time to time all  or any portion of its distribution  fee
and  each of the Distributor and the Adviser is free to make additional payments
out of its own  assets to promote  the sale of  Fund shares, including  payments
that  compensate financial institutions for distribution services or shareholder
services.
 
    The Plan is designed to compensate the Distributor for its services, not  to
reimburse  the Distributor for its expenses,  and the Distributor may retain any
portion of the fee that it does not expend in fulfillment of its obligations  to
the Fund.
 
    EXPENSES.   Each Portfolio is responsible  for payment of certain other fees
and expenses  (including  legal  fees, accountants'  fees,  custodial  fees  and
printing  and mailing  costs) specified  in the  Administration and Distribution
Agreements.
 
                               PURCHASE OF SHARES
 
   
    Class A and Class B shares of the Non-Money Portfolios and Class A shares of
the Money Portfolios  may be  purchased, without  sales commission,  at the  net
asset value per share next determined after receipt of the purchase order by the
Non-Money  Portfolio and, in the case of the Money Portfolios, at the price next
determined after  Federal  Funds  are  available to  the  Money  Portfolio.  See
"Valuation of Shares."
    
 
                                       33
<PAGE>
   
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
    
 
   
    For  an account for a Non-Money Portfolio opened on or after January 2, 1996
(a "New Non-Money Account"), the minimum initial investment and minimum  account
size  are  $500,000 for  Class A  shares and  $100,000 for  Class B  shares. The
minimum initial investment for each Money Portfolio is $50,000. Managed Accounts
may purchase  Class  A shares  without  being  subject to  any  minimum  initial
investment  or  minimum  account  size  requirements  for  a  Portfolio account.
Officers of the Adviser  and its affiliates  are subject to  the minimums for  a
Portfolio  account, except they may purchase Class B shares subject to a minimum
initial investment and minimum account size of $5,000 for a Portfolio account.
    
 
   
    If the value  of a  New Non-Money Account  containing Class  A shares  falls
below  $500,000  (but  remains  at or  above  $100,000)  because  of shareholder
redemption(s), the Fund will  notify the shareholder, and  if the account  value
remains  below  $500,000 (but  remains at  or above  $100,000) for  a continuous
60-day period, the Class A shares in such account will convert to Class B shares
and will be subject to the distribution fee and other features applicable to the
Class B shares. The Fund,  however, will not convert Class  A shares to Class  B
shares  based solely upon changes in the  market that reduce the net asset value
of shares. Under current  tax law, conversions between  share classes are not  a
taxable event to the shareholder.
    
 
   
    Shares  in  a  Portfolio  account  opened  prior  to  January  2,  1996 were
designated Class A shares  on January 2, 1996.  Shares in a Non-Money  Portfolio
account  opened prior to January 2, 1996  (each, a "Pre 1996 Non-Money Account")
with a value  of $100,000 or  more on March  1, 1996 (a  "Grandfathered Class  A
Account")  remain Class A  shares regardless of  account size thereafter. Except
for shares in a Managed Account, shares  in a Pre-1996 Non-Money Account with  a
value of less than $100,000 on March 1, 1996 (a "Grandfathered Class B Account")
convert  to Class B shares on March  1, 1996. Grandfathered Class A Accounts and
Managed Accounts are not subject  to conversion from Class  A shares to Class  B
shares.
    
 
   
    Investors  may also invest in the Fund  by purchasing shares through a trust
department, broker, dealer, agent, financial planner, financial services firm or
investment adviser.  An  investor  may  be  charged  an  additional  service  or
transaction fee by that institution. The minimum investment levels may be waived
at  the discretion  of the  Adviser for (i)  certain employees  and customers of
Morgan Stanley  or  its  affiliates  and  certain  trust  departments,  brokers,
dealers,  agents, financial  planners, financial  services firms,  or investment
advisers that  have  entered  into  an agreement  with  Morgan  Stanley  or  its
affiliates;  and (ii) retirement and deferred compensation plans and trusts used
to fund such  plans, including,  but not limited  to, those  defined in  Section
401(a),  403(b) or  457 of the  Internal Revenue  Code of 1986,  as amended, and
"rabbi trusts".  The  Fund  reserves  the  right  to  modify  or  terminate  the
conversion  features of  the shares  as stated above  at any  time upon 60-days'
notice to shareholders.
    
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
   
    If the value  of a  New Non-Money Account  falls below  $100,000 because  of
shareholder  redemption(s), the  Fund will  notify the  shareholder, and  if the
account value remains below $100,000 for a continuous 60-day period, the  shares
in such accounts are subject to redemption by the Fund and, if redeemed, the net
asset  value of such shares will be  promptly paid to the shareholder. The Fund,
however, will not  redeem shares based  solely upon changes  in the market  that
reduce the net asset value of shares.
    
 
   
    For  purposes of redemptions by the Fund, the foregoing minimum account size
requirements do not apply  to New Non-Money Accounts  containing Class B  shares
held    by   officers   of    the   Adviser   or    its   affiliates.   However,
    
 
                                       34
<PAGE>
   
if the value of such account held by an officer of the Adviser or its affiliates
falls below $5,000 because  of shareholder redemption(s),  the Fund will  notify
the  shareholder, and if the account value remains below $5,000 for a continuous
60-day period, the shares in such account are subject to redemption by the  Fund
and,  if redeemed, the net  asset value of such shares  will be promptly paid to
the shareholder.
    
 
   
    Grandfathered Class A Accounts, Grandfathered  Class B Accounts and  Managed
Accounts are not subject to involuntary redemption.
    
 
   
    If  a shareholder reduces its total investment  in Class A shares of a Money
Portfolio to less than $10,000, the investment may be subject to redemption.
    
 
   
    The  Fund  reserves  the  right  to  modify  or  terminate  the  involuntary
redemption  features of  the shares as  stated above  at any time  upon 60 days'
notice to shareholders.
    
 
   
CONVERSION FROM CLASS B TO CLASS A SHARES
    
 
   
    If the value of Class B  shares in a Non-Money Portfolio account  increases,
whether  due to shareholder  share purchases or market  activity, to $500,000 or
more, the Class B shares will convert to Class A shares. Under current tax  law,
such  conversion  is not  a taxable  event  to the  shareholder. Class  A shares
converted from  Class B  shares are  subject to  the same  minimum account  size
requirements  that are applicable  to New Non-Money  Accounts containing Class A
shares, as stated above. The Fund reserves the right to modify or terminate this
conversion feature at any time upon 60 days' notice to shareholders.
    
 
INITIAL PURCHASES DIRECTLY FROM THE FUND
 
   
    The Fund's determination of an investor's eligibility to purchase shares  of
a  given class will  take precedence over  the investor's selection  of a class.
Assuming the investor is eligible for the  class, the Fund will select the  most
favorable class for the investor, if the investor has not done so.
    
 
   
1) BY  CHECK.   An account may  be opened  by completing and  signing an Account
   Registration Form and mailing it, together with a check ($500,000 minimum for
   Class A shares  of each  Non-Money Portfolio,  $100,000 minimum  for Class  B
   shares  of  each  Non-Money Portfolio,  and  $50,000 minimum  for  each Money
   Portfolio, with certain  exceptions for Morgan  Stanley employees and  select
   customers,  including  those who  participate  in the  Automatic  Purchase of
   Portfolio  Shares  program  described  below)  payable  to  "Morgan   Stanley
   Institutional Fund, Inc. -- [portfolio name]", to:
    
 
   
      Morgan Stanley Institutional Fund, Inc.
      P.O. Box 2798
      Boston, Massachusetts 02208-2798
    
 
   
     Payment will  be accepted only  in U.S. dollars,  unless prior approval for
  payment by  other currencies  is given  by the  Fund. The  Portfolio(s) to  be
  purchased should be designated on the Account Registration Form. For purchases
  by  check,  the Fund  is  ordinarily credited  with  Federal Funds  within one
  business day. Thus your purchase of shares by check is ordinarily credited  to
  your  account  at the  net asset  value  per share  of the  relevant Portfolio
  determined on the next business day after receipt.
    
 
                                       35
<PAGE>
   
2) BY FEDERAL  FUNDS WIRE.   Purchases  may be  made by  having your  bank  wire
   Federal  Funds to the Fund's bank account.  In order to ensure prompt receipt
   of your Federal Funds Wire, it is important that you follow these steps:
    
 
   
A.  Telephone  the Fund  (toll free: 1-800-548-7786)  and provide  us with  your
    name,  address,  telephone  number, Social  Security  or  Tax Identification
    Number, the  portfolio(s) selected,  the class  selected, the  amount  being
    wired,  and by  which bank.  We will  then provide  you with  a Fund account
    number. (Investors with existing accounts should also notify the Fund  prior
    to wiring funds.)
    
 
   
B.    Instruct  your  bank to  wire  the  specified amount  to  the  Fund's Wire
    Concentration Bank Account (be  sure to have your  bank include the name  of
    the  portfolio(s)  selected,  the  class  selected  and  the  account number
    assigned to you) as follows:
    
 
   
    Chase Manhattan Bank, N.A.
    One Manhattan Plaza
    New York, NY 10081-1000
    ABA#021000021
    DDA#910-2-733293
    Attn: Morgan Stanley Institutional Fund, Inc.
    Ref: (Portfolio name, your account number, your account name)
    
 
   
    Please call the Fund at 1-800-548-7786 prior to wiring funds.
    
 
   
C.  Complete  the Account Registration  Form and  mail it to  the address  shown
    thereon.
    
 
   
  Purchase  orders for shares of  the Portfolio which are  received prior to the
  regular close of the NYSE (currently 4:00 p.m. Eastern Time) will be  executed
  at  the price computed  on the date of  receipt as long  as the Transfer Agent
  receives payment by check or  in Federal Funds prior  to the regular close  of
  the NYSE on such day.
    
 
   
  Federal Funds purchase orders will be accepted only on a day on which the Fund
  and Chase (the "Custodian Bank") are open for business. Share purchases of the
  Money Market Portfolio in Federal Funds received by 12:00 noon (Eastern Time),
  and  share purchases of the Municipal  Money Market Portfolio in Federal Funds
  received by 11:00 a.m. (Eastern Time) will begin to earn income on the day  of
  receipt. Your bank may charge a service fee for wiring Federal Funds.
    
 
3) BY  BANK WIRE.   The  same procedure outlined  under "By  Federal Funds Wire"
   above must be  followed in  purchasing shares  by bank  wire. However,  money
   transferred  by bank wire may or may  not be converted into Federal Funds the
   same day, depending on the time the  money is received and the bank  handling
   the wire. Prior to such conversion, an investor's money will not be invested.
   For  the Money Market and Municipal Money  Market Portfolios, if money is not
   converted the same day, it will be converted the next business day and shares
   will be  purchased  at  the  net  asset  value  next  determined  after  such
   conversion. Your bank may charge a service fee for wiring funds.
 
   
4) AUTOMATIC  PURCHASE OF PORTFOLIO SHARES.   Free cash balances (i.e., any cash
   that is available on demand at the close of the previous business day)  which
   are  held in  certain eligible  accounts at  Morgan Stanley  Asset Management
   Inc., Morgan Stanley or  any other affiliated  investment adviser or  broker,
   and which are
    
 
                                       36
<PAGE>
   selected  at the discretion of the Adviser, will be automatically invested on
   the next  business day  at net  asset value  in shares  of the  Money  Market
   Portfolio or the Municipal Money Market Portfolio. A shareholder may elect in
   writing  from  time to  time  in which  portfolio  to invest.  This automatic
   purchase  facility  permits  certain   eligible  investment  management   and
   brokerage  customers  of  Morgan Stanley  to  have their  free  cash balances
   invested in portfolio shares on a daily basis pending other investments.
 
ADDITIONAL INVESTMENTS
 
   
    You may  add to  your account  at any  time (minimum  additional  investment
$1,000  for each portfolio,  except for automatic  reinvestment of dividends and
capital gains  distributions for  which  there are  no minimums)  by  purchasing
shares  at net asset  value by mailing a  check to the  Fund (payable to "Morgan
Stanley Institutional Fund, Inc. -- [Portfolio  name]") at the above address  or
by  wiring monies to the Custodian Bank  as outlined above. It is very important
that your account name,  portfolio name and the  class selected be specified  in
the  letter or  wire to  assure proper  crediting to  your account.  In order to
ensure that your wire orders are invested promptly, you are requested to  notify
one  of the Fund's representatives (toll-free  1-800-548-7786) prior to the wire
date. Additional investments will  be applied to  purchase additional shares  in
the same class held by a shareholder in a Portfolio account.
    
 
   
OTHER PURCHASE INFORMATION
    
 
   
    The  purchase price  of the  Class A  and Class  B shares  of each Non-Money
Portfolio is the net  asset value next determined  after the order is  received.
See  "Valuation of  Shares." An  order to purchase  shares of  the Fixed Income,
Municipal Bond,  Mortgage-Backed Securities  or High  Yield Portfolios  received
prior  to the regular  close of the  New York Stock  Exchange ("NYSE"), which is
currently 4:00 p.m. Eastern Time, will be executed at the price computed on  the
date  of receipt; an order received after the  regular close of the NYSE will be
executed at the  price computed the  next day the  NYSE is open  as long as  the
Transfer  Agent  receives payment  by check  or  in Federal  Funds prior  to the
regular close of the NYSE on such day. Orders for the purchase of shares of  the
Money  Market Portfolio or Municipal Money  Market Portfolio become effective on
the business day Federal Funds are  received, and the purchase will be  effected
at the net asset value next computed after receipt.
    
 
   
    Although  the legal rights of Class A  and Class B shares will be identical,
the different expenses borne  by each class will  result in different net  asset
values  and dividends. The net  asset value of Class  B shares will generally be
lower than the net asset value of Class A shares as a result of the distribution
expense charged to Class B shares. It  is expected, however, that the net  asset
value  per share of the two classes  will tend to converge immediately after the
recording of dividends  which will  differ by  approximately the  amount of  the
distribution expense accrual differential between the classes.
    
 
   
    In  the interest  of economy and  convenience, and because  of the operating
procedures of the  Fund, certificates  representing shares  of the  Portfolio(s)
will  not be issued. All  shares purchased are confirmed  to you and credited to
your account on the Fund's  books maintained by the  Adviser or its agents.  You
will  have  the same  rights and  ownership with  respect to  such shares  as if
certificates had been issued.
    
 
   
    To ensure that checks are collected by the Fund, withdrawals of  investments
made  by check are  not presently permitted  until payment for  the purchase has
been received  which may  take  up to  eight business  days  after the  date  of
purchase.  As a condition  of this offering,  if a purchase  is cancelled due to
nonpayment or
    
 
                                       37
<PAGE>
   
because your check does not clear, you will be responsible for any loss the Fund
or its agents  incur. If  you are  already a  shareholder, the  Fund may  redeem
shares from your account(s) to reimburse the Fund or its agents for any loss. In
addition,  you may be prohibited or restricted from making future investments in
the Fund.
    
 
   
    Investors may  also invest  in the  Fund by  purchasing shares  through  the
Distributor.
    
 
   
EXCESSIVE TRADING
    
 
   
    Frequent   trades  involving  either  substantial   portfolio  assets  or  a
substantial portion of your  account or accounts controlled  by you can  disrupt
management  of a portfolio and raise its expenses. Consequently, in the interest
of all the stockholders of each Portfolio and each Portfolio's performance,  the
Fund  may in its discretion bar a  stockholder that engages in excessive trading
of shares of any class  of a portfolio from further  purchases of shares of  the
Fund  for an indefinite period. The Fund  considers excessive trading to be more
than one purchase and sale involving shares of the same class of a portfolio  of
the  Fund  within  any  120-day  period. As  an  example,  exchanging  shares of
portfolios of the Fund as follows amounts to excessive trading: exchanging Class
A shares of Portfolio A for Class A shares of Portfolio B, then exchanging Class
A shares of Portfolio B for Class  A shares of Portfolio C and again  exchanging
Class A shares of Portfolio C for Class A shares of Portfolio B within a 120-day
period.  Two  types  of transactions  are  exempt from  these  excessive trading
restrictions: (1) trades  exclusively between money  market portfolios; and  (2)
trades  done  in  connection  with  an asset  allocation  service,  such  as TFM
Accounts, managed or advised by MSAM and/or any of its affiliates.
    
 
   
                              REDEMPTION OF SHARES
    
 
   
    You may  withdraw all  or  any portion  of the  amount  in your  account  by
redeeming  shares at any time. Please note  that purchases made by check are not
permitted to be redeemed until payment of the purchase has been collected, which
may take up to eight business days after purchase. The Fund will redeem Class  A
and  Class B shares of each Non-Money Portfolio and Class A shares of each Money
Portfolio at the  next determined net  asset value of  shares of the  applicable
class.  On days that both the NYSE and the Custodian Bank are open for business,
the net  asset  value  per share  of  the  Fixed Income,  Global  Fixed  Income,
Municipal   Bond,  Mortgage-Backed  Securities  and  High  Yield  Portfolios  is
determined at the  regular close  of trading of  the NYSE  (currently 4:00  p.m.
Eastern  Time), and the net asset value  per share of the Municipal Money Market
Portfolio is determined at 11:00 a.m. (Eastern Time) and the net asset value per
share of the Money Market Portfolio is determined at 12:00 p.m. (Eastern  Time).
Shares  of a Portfolio may  be redeemed by mail or  telephone. No charge is made
for redemption. Any redemption may  be more or less  than the purchase price  of
your  shares  depending  on,  among  other  factors,  the  market  value  of the
investment securities held by the Portfolio.
    
 
   
BY MAIL
    
 
   
    Each Non-Money Portfolio will redeem its Class A and Class B shares and each
Money Portfolio will  redeem its  Class A  shares at  the net  asset value  next
determined  after your request is  received if the request  is received in "good
order." Your request should be  addressed to Morgan Stanley Institutional  Fund,
Inc., P.O. Box 2798, Boston, Massachusetts 02208-2798, except that deliveries by
overnight  courier  should be  addressed to  Morgan Stanley  Institutional Fund,
Inc., c/o  Chase  Global Funds  Services  Company, 73  Tremont  Street,  Boston,
Massachusetts 02108-3913.
    
 
                                       38
<PAGE>
   
    "Good  order"  means that  the  request to  redeem  shares must  include the
following documentation:
    
 
   
        (a)  A letter of instruction or a stock assignment specifying the  class
    and  number  of  shares or  dollar  amount  to be  redeemed,  signed  by all
    registered owners  of  the shares  in  the exact  names  in which  they  are
    registered;
    
 
   
        (b)   Any  required   signature  guarantees   (see  "Further  Redemption
    Information" below); and
    
 
   
        (c)   Other supporting  legal documents,  if required,  in the  case  of
    estates,  trusts, guardianships,  custodianships, corporations,  pension and
    profit-sharing plans and other organizations.
    
 
   
    Shareholders who are uncertain of requirements for redemption should consult
with a Morgan Stanley Institutional Fund representative.
    
 
   
BY TELEPHONE
    
 
   
    Provided you have previously elected the Telephone Redemption Option on  the
Account  Registration  Form, you  can  request a  redemption  of your  shares by
calling the Fund  and requesting  the redemption proceeds  be mailed  to you  or
wired  to your bank.  Please contact one of  Morgan Stanley Institutional Fund's
representatives for further details. In times of drastic market conditions,  the
telephone  redemption option  may be difficult  to implement.  If you experience
difficulty in making a telephone redemption, your request may be made by mail or
overnight courier and will be implemented at the net asset value next determined
after it is  received. Redemption requests  sent to the  Fund through  overnight
courier  must  be sent  to Morgan  Stanley Institutional  Fund, Inc.,  c/o Chase
Global  Funds  Services  Company,  73  Tremont  Street,  Boston,   Massachusetts
01208-3913.  The Fund and the Fund's  transfer agent (the "Transfer Agent") will
employ reasonable procedures  to confirm that  the instructions communicated  by
telephone  are  genuine.  These  procedures include  requiring  the  investor to
provide certain personal identification  information at the  time an account  is
opened  and  prior  to effecting  each  transaction requested  by  telephone. In
addition, all telephone transaction requests will be recorded and investors  may
be  required  to provide  additional  telecopied written  instructions regarding
transaction  requests.  Neither  the  Fund  nor  the  Transfer  Agent  will   be
responsible  for any loss, liability, cost or expense for following instructions
received by telephone that either of them reasonably believes to be genuine.
    
 
   
    To change the name of the  commercial bank or account designated to  receive
redemption  proceeds, a written request must be  sent to the Fund at the address
above. Requests to change the bank or account must be signed by each shareholder
and each signature must be guaranteed.
    
 
FURTHER REDEMPTION INFORMATION
 
    Normally the  Fund will  make payment  for all  shares redeemed  within  one
business  day of receipt  of the request, but  in no event  will payment be made
more than  seven days  after receipt  of  a redemption  request in  good  order.
However,  payments to investors  redeeming shares which  were purchased by check
will not be made until  payment for the purchase  has been collected, which  may
take  up to 8 days after the date of purchase. The Fund may suspend the right of
redemption or postpone  the date upon  which redemptions are  effected at  times
when  the NYSE is closed, or under  any emergency circumstances as determined by
the Securities and Exchange Commission (the "Commission").
 
    If the Board  of Directors determines  that it would  be detrimental to  the
best  interests of  the remaining  shareholders of  a Portfolio  to make payment
wholly  or  partly  in   cash,  the  Fund  may   pay  the  redemption   proceeds
 
                                       39
<PAGE>
in  whole or in part by a distribution-in-kind of securities held by a Portfolio
in lieu  of  cash  in  conformity  with  applicable  rules  of  the  Commission.
Distributions-in-kind  will be made in  readily marketable securities. Investors
may incur brokerage charges on the  sale of Portfolio securities so received  in
payment of redemptions.
 
    To  protect  your account,  the Fund  and its  agents from  fraud, signature
guarantees are required for  certain redemptions to verify  the identity of  the
person  who has  authorized a redemption  from your account.  Please contact the
Fund for further  information. See "Redemption  of Shares" in  the Statement  of
Additional Information.
 
                              SHAREHOLDER SERVICES
 
   
EXCHANGE FEATURES
    
 
   
    You  may exchange shares that you own in a Portfolio for shares of any other
available portfolio of the Fund (other than the International Equity  Portfolio,
which  is closed to new investors). In exchanging for shares of a portfolio with
more than one class,  the class of  shares you receive in  the exchange will  be
determined  in the same manner  as any other purchase of  shares and will not be
based on the  class of shares  surrendered for the  exchange. Consequently,  the
same  minimum initial  investment and minimum  account size  for determining the
class of shares received in the  exchange will apply. See "Purchase of  Shares."
Shares of the portfolios may be exchanged by mail or telephone. The privilege to
exchange shares by telephone is automatic and made available without shareholder
election.  Before you make  an exchange, you  should read the  prospectus of the
portfolio(s) in which  you seek to  invest. Because an  exchange transaction  is
treated  as a redemption followed by a purchase, an exchange would be considered
a taxable event for shareholders subject to tax. The exchange privilege is  only
available  with  respect  to  portfolios  that  are  registered  for  sale  in a
shareholder's state  of residence.  The exchange  privilege may  be modified  or
terminated by the Fund at any time upon 60 days' notice to shareholders.
    
 
   
BY MAIL
    
 
   
    In  order to  exchange shares  by mail, you  should include  in the exchange
request the name, class of shares and account number of your current  Portfolio,
the  names of the portfolio(s) and class(es)  of shares into which you intend to
exchange shares, and the signatures of all registered account holders. Send  the
exchange  request to  Morgan Stanley  Institutional Fund,  Inc., P.O.  Box 2798,
Boston, MA 02208-2798.
    
 
   
BY TELEPHONE
    
 
   
    When exchanging shares by  telephone, have ready the  name, class of  shares
and account number of the current portfolio, the name(s) of the portfolio(s) and
class(es)  of  shares into  which  you intend  to  exchange shares,  your Social
Security number  or Tax  I.D. number,  and your  account address.  Requests  for
telephone  exchanges received prior to 4:00 p.m. (Eastern Time) are processed at
the close of business that same day based on the net asset value of the class of
the portfolios involved  in the  exchange of shares  at the  close of  business.
Requests  received after 4:00 p.m. are processed  the next business day based on
the net  asset  value  determined at  the  close  of such  day.  For  additional
information   regarding  responsibility  for   the  authenticity  of  telephoned
instructions, see "Redemption of Shares -- By Telephone" above.
    
 
   
TRANSFER OF REGISTRATION
    
 
   
    You may transfer  the registration  of any of  your Fund  shares to  another
person  by writing  to Morgan Stanley  Institutional Fund, Inc.,  P.O. Box 2798,
Boston,  Massachusetts  02208-2798.   As  in  the   case  of  redemptions,   the
    
 
                                       40
<PAGE>
   
written  request must be received in good order before any transfer can be made.
Transferring the  registration of  shares  may affect  the eligibility  of  your
account  for  a  given  class  of  the  Portfolios'  shares  and  may  result in
involuntary conversion or redemption  of your shares.  See "Purchase of  Shares"
above.
    
 
   
                              VALUATION OF SHARES
    
 
   
    The  net  asset value  per  share of  a class  of  shares of  each Non-Money
Portfolio is determined  by dividing  the total  market value  of the  Non-Money
Portfolio's  investments and other  assets attributable to  such class, less all
liabilities attributable  to such  class,  by the  number of  total  outstanding
shares of such a class of the Non-Money Portfolio. Net asset value is calculated
separately  for each class  of the Portfolio.  Net asset value  per share of the
Non-Money Portfolios is determined as of the  regular close of the NYSE on  each
day  that the NYSE is open for  business. Securities listed on a U.S. securities
exchange for which market quotations are available are valued at the last quoted
sale price  on  the day  the  valuation is  made.  Price information  on  listed
securities  is taken from  the exchange where the  security is primarily traded.
Securities listed  on a  foreign exchange  are valued  at their  closing  price.
Unlisted  securities and listed securities not  traded on the valuation date for
which market quotations are not readily available are valued at a price within a
range not exceeding the current asked price nor less than the current bid price.
The current bid  and asked prices  are determined  either based on  the bid  and
asked  prices  quoted on  such valuation  date  by two  reputable brokers  or as
provided by a reliable pricing service.
    
 
   
    Bonds and other fixed income securities are valued according to the broadest
and most representative  market, which will  ordinarily be the  over-the-counter
market.  Net asset value includes interest  on fixed income securities, which is
accrued daily unless collection is in doubt. In addition, bonds and other  fixed
income  securities may be  valued on the  basis of prices  provided by a pricing
service when such prices are believed to  reflect the fair market value of  such
securities.  The prices  provided by  a pricing  service are  determined without
regard to bid  or last  sale prices, but  take into  account institutional  size
trading  in similar  groups of  securities and  any developments  related to the
specific securities. Securities not priced in this manner are valued at the most
recently quoted bid price, or, when securities exchange valuations are used,  at
the  latest quoted  sale price  on the  day of  valuation. If  there is  no such
reported sale,  the  latest quoted  bid  price  will be  used.  Debt  securities
purchased  with remaining maturities of 60 days  or less are valued at amortized
cost, if it approximates market value. In the event that amortized cost does not
approximate market value, market prices as determined above will be used.
    
 
   
    The value of other assets and securities for which no quotations are readily
available (including  restricted  and  unlisted foreign  securities)  and  those
securities  for which it is inappropriate to determine prices in accordance with
the above-stated procedures  are determined in  good faith at  fair value  using
methods  determined by the  Board of Directors. For  purposes of calculating net
asset value per share, all assets and liabilities initially expressed in foreign
currencies will be converted into U.S. dollars at the mean of the bid price  and
asked price for such currencies against the U.S. dollar last quoted by any major
bank.
    
 
   
    Although  the legal rights of Class A  and Class B shares will be identical,
the different expenses borne  by each class will  result in different net  asset
values  and dividends for the class.  Dividends will differ by approximately the
amount of the distribution expense  accrual differential among the classes.  The
net  asset value of  Class B shares will  generally be lower  than the net asset
value of Class A shares as a result of the distribution expense charged to Class
B shares.
    
 
                                       41
<PAGE>
   
    The net asset  value per share  of each  of the Money  Market and  Municipal
Money Market Portfolios is determined by subtracting the Portfolio's liabilities
(including  accrued expenses and dividends payable)  from the total value of the
Portfolio's investments and other  assets and dividing the  result by the  total
number of outstanding shares of the Portfolio. The net asset values per share of
the  Municipal  Money  Market  Portfolio  and  the  Money  Market  Portfolio are
determined at 11:00  a.m. and 12:00  noon (Eastern Time),  respectively, on  the
days  on which the NYSE is open. For the purpose of calculating each Portfolio's
net asset value per share, securities are valued by the "amortized cost"  method
of  valuation, which does not take into account unrealized gains or losses. This
involves valuing an instrument  at its cost and  thereafter assuming a  constant
amortization to maturity of any discount or premium, regardless of the impact of
fluctuating  interest rates  on the market  value of the  instrument. While this
method provides certainty in  valuation, it may result  in periods during  which
the  value, as determined by  amortized cost, is higher  or lower than the price
the Portfolio would receive if it sold the instrument.
    
 
   
                            PERFORMANCE INFORMATION
    
 
   
    The Fund may from time to time advertise total return for each class of  the
Fixed  Income, Global  Fixed Income, Municipal  Bond, Mortgage-Backed Securities
and High Yield Portfolios. In addition, from time to time the Fund may advertise
"yield" for the Global  Fixed Income, Municipal Bond,  High Yield, Money  Market
and Municipal Money Market Portfolios and "effective yield" for the Money Market
and  Municipal Money Market Portfolios. In  addition to these yield figures, the
Municipal Bond  and  Municipal  Money  Market  Portfolio  may  advertise  a  tax
equivalent  yield. THESE FIGURES ARE BASED ON HISTORICAL PERFORMANCE AND ARE NOT
INTENDED TO  INDICATE  FUTURE PERFORMANCE.  The  "total return"  shows  what  an
investment in a class of the Portfolio would have earned over a specified period
of  time (such as  one, five or  ten years) assuming  that all distributions and
dividends by the Portfolio were reinvested in the same class on the reinvestment
dates during the period. Total return does not take into account any federal  or
state  income taxes that may  be payable on dividends  and distributions or upon
redemption. The "yield"  of the  Global Fixed  Income, Municipal  Bond and  High
Yield  Portfolios  refers  to  the  income generated  by  an  investment  in the
Portfolio over a  one-month or  30-day period, while  the "yield"  of the  Money
Market  and Municipal Money Market Portfolios  refers to the income generated by
an investment in  the Portfolio over  a seven-day period  (which period will  be
stated  in the  advertisement). This income  is then "annualized."  That is, the
amount of income generated by the investment during that 30- or seven-day period
is assumed to be generated  each 30-day period for  twelve periods or each  week
over  a 52-week  period, and  is shown  as a  percentage of  the investment. The
"effective yield"  is  calculated similarly  but,  when annualized,  the  income
earned  on  an investment  in the  Portfolio  is assumed  to be  reinvested. The
"effective yield"  will be  slightly  higher than  the  "yield" because  of  the
compounding effect of this assumed reinvestment. A "tax equivalent yield" is the
"yield"  of the Portfolio increased by an amount based on an assumed rate of tax
for a  shareholder.  For  further  information  concerning  these  figures,  see
"Calculation  of  Yield  and  Total  Return"  in  the  Statement  of  Additional
Information. The  Fund  may  also use  comparative  performance  information  in
marketing   the  Portfolios'  shares,  including  data  from  Lipper  Analytical
Services, Inc.,  Donoghue's  Money  Fund Report,  other  industry  publications,
business periodicals, rating services and market indices.
    
 
   
    The  performance figures  for Class  B shares  will generally  be lower than
those for Class  A shares because  of the  distribution fee charged  to Class  B
shares.
    
 
                                       42
<PAGE>
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
 
   
FIXED INCOME, GLOBAL FIXED INCOME, MUNICIPAL BOND, MORTGAGE-BACKED SECURITIES
AND HIGH YIELD PORTFOLIOS
    
 
   
    All  income dividends and capital gains  distributions for a class of shares
of each  Non-Money  Portfolio will  automatically  be reinvested  in  additional
shares of such class at net asset value, except that, upon written notice to the
Fund  or by checking off the appropriate  box in the Distribution Option Section
on the Account  Registration Form,  a shareholder  may elect  to receive  income
dividends and capital gains distributions in cash.
    
 
   
    Each  Non-Money Portfolio, except the Global Fixed Income Portfolio, expects
to distribute substantially  all of  its net investment  income in  the form  of
monthly  dividends and the  Global Fixed Income  Portfolio expects to distribute
substantially all  of  its  net  investment income  in  the  form  of  quarterly
dividends.  Net  realized  gains  of each  Non-Money  Portfolio,  if  any, after
reduction for  any tax  loss carryforwards  will also  be distributed  annually.
Confirmations of the purchases of shares of the Non-Money Portfolios through the
automatic  reinvestment of income dividends and capital gains distributions will
be provided, pursuant  to Rule 10b-10(b)  under the Securities  Exchange Act  of
1934,  as amended, on the next monthly client statement following such purchases
of shares. Consequently, confirmations of such purchases will not be provided at
the time of completion of such purchases as might otherwise be required by  Rule
10b-10.
    
 
   
    Undistributed   net  investment   income  is  included   in  each  Non-Money
Portfolio's net assets for the purpose of calculating net asset value per share.
Therefore, on the "ex-dividend" date, the net asset value per share excludes the
dividend (I.E., is reduced by the  per share amount of the dividend).  Dividends
paid  shortly after the purchase of shares  by an investor, although in effect a
return of capital, are taxable to shareholders.
    
 
   
    Because of  the  distribution  fee  and  any  other  expenses  that  may  be
attributable  to the  Class B  shares, the  net income  attributable to  and the
dividends payable  on  Class  B  shares  will  be  lower  than  the  net  income
attributable  to and the dividends  payable on Class A  shares. As a result, the
net asset value per share of the classes of each Non-Money Portfolio will differ
at times. Expenses of each Non-Money  Portfolio allocated to a particular  class
of shares thereof will be borne on a pro rata basis by each outstanding share of
that class.
    
 
MONEY MARKET AND MUNICIPAL MONEY MARKET PORTFOLIOS
 
    Net  investment income  is computed and  dividends declared as  of 1:00 p.m.
(Eastern time),  on each  day. Such  dividends are  payable to  Municipal  Money
Market  Portfolio shareholders of record as of 11:00 a.m. (Eastern time) on that
day and  to Money  Market Portfolio  shareholders  of record  as of  12:00  noon
(Eastern  time)  on  that day,  if  the Fund  and  Custodian Bank  are  open for
business. This means that shareholders whose purchase orders become effective as
of 12:00 noon (for the Money Market Portfolio) or 11:00 a.m. (for the  Municipal
Money  Market Portfolio) receive  the dividend for  that day. Dividends declared
for Saturdays, Sundays and holidays are payable to shareholders of record as  of
4:00  p.m. on the last  preceding day the Fund and  its Custodian Bank were open
for business.
 
    For the purpose of calculating dividends, net income of each Money Portfolio
shall consist  of interest  earned, including  any discount  or premium  ratably
amortized  to  the  date of  maturity,  minus  estimated expenses  of  the Money
Portfolio.
 
    Each Money Portfolio's daily dividends are accrued throughout the month  and
are  distributed on the fifteenth  calendar day of each  month (or next business
day   if    the   fifteenth    calendar   day    falls   on    a   holiday    or
 
                                       43
<PAGE>
weekend).  Dividends of each  Money Portfolio are  payable in additional shares,
except that, upon written notice to the Fund or by checking off the  appropriate
box  in  the Distribution  Option Section  on the  Account Registration  Form, a
shareholder may  elect  to  receive  income  dividends  and  any  capital  gains
distributions in cash.
 
    Each  shareholder receives a  monthly statement summarizing  activity in the
account. If at any time a shareholder wishes to withdraw all of the funds in  an
account,  the  proceeds  will be  sent  to  the shareholder  by  wire  or check,
according to the  shareholder's instructions. If  the withdrawal is  by wire,  a
check  in the amount of the income  to the shareholder's account through the day
of withdrawal  will be  mailed to  the  shareholder on  the next  business  day.
Withdrawals by check will include accrued income through the date of withdrawal.
 
    Net  realized short-term capital gains, if  any, of each Money Portfolio are
to  be  distributed  whenever  the  Board  of  Directors  determine  that   such
distributions  would be in the best interest  of shareholders, but in any event,
at least  once  a year.  The  Money Portfolios  do  not expect  to  realize  any
long-term  capital  gains.  Should any  such  gains  be realized,  they  will be
distributed annually.
 
    It is an objective  of management to  maintain the price  per share of  each
Money  Portfolio as computed for the purpose of sales and redemptions at exactly
$1.00. In the event the Board of  Directors determine that a deviation from  the
$1.00 per share price may exist which may result in a material dilution or other
unfair  results to investors or existing shareholders, they will take corrective
action  they  regard  as  necessary  and  appropriate,  including  the  sale  of
instruments from a Money Portfolio prior to maturity to realize capital gains or
losses;  shortening average portfolio maturity;  withholding dividends; making a
special capital distribution; or redemptions of shares in kind.
 
                                     TAXES
 
GENERAL
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
    No attempt has been made to  present a detailed explanation of the  federal,
state,  or  local  income tax  treatment  of  a Portfolio  or  its shareholders.
Accordingly, shareholders  are urged  to consult  their tax  advisors  regarding
specific questions as to federal, state and local income taxes.
    Each  Portfolio  is treated  as  a separate  entity  for federal  income tax
purposes and is not  combined with the Fund's  other Portfolios. Each  Portfolio
intends  to qualify for the special  tax treatment afforded regulated investment
companies under Subchapter M of the Code, so that the Portfolio will be relieved
of federal income tax on that part of its net investment income and net  capital
gain that is distributed to shareholders.
    Each  Portfolio distributes substantially  all of its  net investment income
(including, for  this purpose,  net short-term  capital gain)  to  shareholders.
Dividends  from a Portfolio's net investment income (other than "exempt-interest
dividends," described below)  are taxable  to shareholders  as ordinary  income,
whether  received in  cash or  in additional  shares. Such  dividends paid  by a
Portfolio will generally  not qualify for  the 70% dividends-received  deduction
for   corporate  shareholders.  Each  Portfolio  will  report  annually  to  its
shareholders the amount of dividend income qualifying for such treatment.
 
                                       44
<PAGE>
    Distributions of net capital gain (the excess of net long-term capital  gain
over  net  short-term capital  loss) are  taxable  to shareholders  as long-term
capital gain,  regardless  of how  long  shareholders have  held  their  shares.
[Distributions  of net investment  income and net capital  gain are not eligible
for the corporate  dividends-received deduction.] Each  Portfolio sends  reports
annually   to  its  shareholders  of  the  federal  income  tax  status  of  all
distributions made during the preceding year.
    Each  Portfolio  intends   to  make  sufficient   distributions  or   deemed
distributions  of its ordinary income and capital gain net income (the excess of
short-term and long-term  capital gains  over short-term  and long-term  capital
losses)  including any available capital loss carryforwards, prior to the end of
each calendar year to avoid liability for federal excise tax.
    Dividends and  other  distributions  declared by  a  Portfolio  in  October,
November or December of any year and payable to shareholders of record on a date
in  such month will be deemed to have been paid by the Portfolio and received by
the shareholders on December 31  of that year if  the distributions are paid  by
the Portfolio at any time during the following January.
 
   
    The  sale, exchange or  redemption of shares  may result in  taxable gain or
loss to the selling, exchanging or redeeming shareholder, depending upon whether
the fair market value  of the redemption  proceeds exceeds or  is less than  the
Shareholder's  adjusted  basis in  the redeemed,  exchanged  or sold  shares. If
capital gain distributions have been made  with respect to shares that are  sold
at a loss after being held for six months or less, then the loss is treated as a
long-term capital loss to the extent of the capital gain distributions.
    
 
   
    The  conversion of Class A shares to Class  B shares should not be a taxable
event to the shareholder.
    
    Shareholders are urged  to consult  with their tax  advisors concerning  the
application of state and local income taxes to investments in a Portfolio, which
may differ from the federal income tax consequences described above.
THE MUNICIPAL BOND AND MUNICIPAL MONEY MARKET PORTFOLIOS
    The  dividends payable by the Municipal  Bond and the Municipal Money Market
Portfolios from  net tax-exempt  interest from  municipal bonds  and notes  will
qualify  as "exempt-interest dividends" if, at the  close of each quarter of its
taxable year,  at  least 50%  of  the value  of  its total  assets  consists  of
securities  the interest on which  is excludable from gross  income. Each of the
Municipal Bond  and  Municipal  Money  Market Portfolios  intends  to  invest  a
sufficient  portion of its assets in municipal bonds and notes to qualify to pay
"exempt-interest dividends."
    Exempt-interest dividends are excludable  from a shareholder's gross  income
for regular income tax purposes. However, the receipt of such dividends may have
collateral  federal income  tax consequences, including  alternative minimum tax
consequences. In addition,  the receipt of  exempt-interest dividends may  cause
persons  receiving Social Security or Railroad Retirement benefits to be taxable
on a portion  of such  benefits. See  the Statement  of Additional  Information.
Current  federal tax law limits the types  of volume of bonds qualifying for the
federal income  tax exemption  of interest,  which  may have  an effect  on  the
ability   of  the  Portfolios  to  purchase  sufficient  amounts  of  tax-exempt
securities to satisfy the Code's requirement for the payment of  exempt-interest
dividends.
 
                                       45
<PAGE>
    All or a portion of the interest on indebtedness incurred or continued by an
investor  to purchase or carry  shares is not deductible  for federal income tax
purposes. Furthermore,  entities  or persons  who  are "substantial  users"  (or
persons  related  to "substantial  users")  of facilities  financed  by "private
activity bonds"  or  "industrial development  bonds"  should consult  their  tax
advisors  before  purchasing  shares of  the  Portfolios. See  the  Statement of
Additional Information.
    The Portfolios will  report annually  to their shareholders  the portion  of
dividends  that is taxable  and the portion  that is tax-exempt  based on income
received by the Portfolios during the year to which the dividends relate.
    The exemption of dividends  paid by the Municipal  Bond and Municipal  Money
Market  Portfolio  for Federal  income tax  purposes may  not result  in similar
exemptions under the laws of a particular state or local taxing authority.  Each
of  the Municipal Bond and Municipal Money Market Portfolio will report annually
to its shareholders  the percentage and  source, on a  state-by-state basis,  of
interest  income  earned on  municipal  bonds and  municipal  notes held  by the
Portfolio during the preceding year.
    THE  TAX  DISCUSSION  SET  FORTH  ABOVE  IS  INCLUDED  HEREIN  FOR   GENERAL
INFORMATION  ONLY. PROSPECTIVE INVESTORS  SHOULD CONSULT THEIR  OWN TAX ADVISERS
WITH RESPECT TO THE TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN A PORTFOLIO.
 
                             PORTFOLIO TRANSACTIONS
 
    The Investment  Advisory  Agreement authorizes  the  Adviser to  select  the
brokers  or  dealers that  will execute  the purchases  and sales  of investment
securities for the Portfolios and directs the Adviser to use its best efforts to
obtain the best available price and most favorable execution with respect to all
transactions for the  Portfolios. The  Fund has  authorized the  Adviser to  pay
higher commissions in recognition of brokerage services which, in the opinion of
the Adviser, are necessary for the achievement of better execution, provided the
Adviser believes this to be in the best interest of the Fund.
 
    Since shares of the Portfolios are not marketed through intermediary brokers
or  dealers, it is  not the Fund's  practice to allocate  brokerage or principal
business on the basis of sales of  shares which may be made through such  firms.
However,  the Adviser may  place portfolio orders  with qualified broker-dealers
who recommend the  Fund's portfolios or  who act  as agents in  the purchase  of
shares of the Fund's portfolios for their clients.
 
    In  purchasing and selling  securities for the Portfolios,  it is the Fund's
policy to seek to obtain quality execution at the most favorable prices, through
responsible  broker-dealers.  In   selecting  broker-dealers   to  execute   the
securities  transactions for the Portfolios, consideration will be given to such
factors as the price of the security,  the rate of the commission, the size  and
difficulty  of  the  order,  the  reliability,  integrity,  financial condition,
general execution and operational capabilities of competing broker-dealers,  and
the  brokerage  and  research services  which  they  provide to  the  Fund. Some
securities considered for investment by  the Portfolios may also be  appropriate
for  other clients  served by  the Adviser.  If purchase  or sale  of securities
consistent with the investment policies of a Portfolio and one or more of  these
other  clients served by  the Adviser is  considered at or  about the same time,
transactions in  such  securities will  be  allocated among  the  Portfolio  and
clients in a
 
                                       46
<PAGE>
manner deemed fair and reasonable by the Adviser. Although there is no specified
formula for allocating such transactions, the various allocation methods used by
the Adviser, and the results of such allocations, are subject to periodic review
by the Fund's Directors.
 
    Subject to the overriding objective of obtaining the best possible execution
of  orders, the Adviser may allocate a portion of the Fund's portfolio brokerage
transactions to Morgan Stanley or broker affiliates of Morgan Stanley. In  order
for  Morgan Stanley or  its affiliates to effect  any portfolio transactions for
the Fund, the commissions, fees or other remuneration received by Morgan Stanley
or such affiliates must be reasonable and fair compared to the commissions, fees
or other  remuneration  paid to  other  brokers in  connection  with  comparable
transactions   involving  similar  securities  being  purchased  or  sold  on  a
securities exchange during a comparable  period of time. Furthermore, the  Board
of Directors of the Fund, including a majority of the Board of Directors who are
not  "interested persons,"  as defined in  the 1940 Act  have adopted procedures
which are reasonably  designed to provide  that any commissions,  fees or  other
remuneration  paid to Morgan Stanley or  such affiliates are consistent with the
foregoing standard.
 
    Portfolio securities will not  be purchased from or  through, or sold to  or
through,  the Adviser or Morgan Stanley  or any "affiliated persons," as defined
in the 1940 Act, of Morgan Stanley when such entities are acting as  principals,
except to the extent permitted by law.
 
   
    Although none of the Portfolios will invest for short-term trading purposes,
investment securities may be sold from time to time without regard to the length
of  time they have been held. For  each Portfolio, it is anticipated that, under
normal circumstances, the annual portfolio  turnover rate will not exceed  100%.
High portfolio turnover involves correspondingly greater transaction costs which
will  be borne directly by the respective Portfolio. In addition, high portfolio
turnover may  result  in  more capital  gains  which  would be  taxable  to  the
shareholders  of the  respective Portfolio. The  tables set  forth in "Financial
Highlights" present the Portfolios' historical turnover rates.
    
 
                              GENERAL INFORMATION
 
DESCRIPTION OF COMMON STOCK
 
   
    The Fund  was organized  as a  Maryland corporation  on June  16, 1988.  The
Articles  of Incorporation, as amended and restated, permit the Fund to issue up
to 34 billion shares of common stock,  with $.001 par value per share.  Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number  of shares the  Fund is authorized  to issue without  the approval of the
shareholders of the  Fund. Subject  to the  notice period  to shareholders  with
respect  to shares held by shareholders, the Board of Directors has the power to
designate one or  more classes of  shares of  common stock and  to classify  and
reclassify  any  unissued shares  with respect  to such  classes. The  shares of
common stock of each  portfolio are currently classified  into two classes,  the
Class A shares and Class B shares, except for the International Small Cap, Money
Market and Municipal Money Market Portfolio, which only offer Class A shares.
    
 
   
    The   shares  of   each  Portfolio,  when   issued,  will   be  fully  paid,
nonassessable, fully transferable and  redeemable at the  option of the  holder.
The  shares have no preference as to conversion, exchange, dividends, retirement
or other features and have no pre  emptive rights. The shares of each  Portfolio
have non-cumulative voting rights, which means that the holders of more than 50%
of  the  shares voting  for  the election  of Directors  can  elect 100%  of the
Directors if they choose to do so.  Persons or organizations owning 25% or  more
of the outstanding shares
    
 
                                       47
<PAGE>
   
of a Portfolio may be presumed to "control" (as that term is defined in the 1940
Act)  that Portfolio. Under  Maryland law, the  Fund is not  required to hold an
annual meeting of its shareholders unless required to do so under the 1940 Act.
    
 
REPORTS TO SHAREHOLDERS
 
    The Fund will send to its  shareholders annual and semi-annual reports;  the
financial  statements  appearing in  annual reports  are audited  by independent
accountants. Monthly unaudited portfolio  data is also  available from the  Fund
upon request.
 
    In addition, the Adviser, or its agent, as Transfer Agent, will send to each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
 
CUSTODIAN
 
    As  of September 1,  1995, domestic securities  and cash are  held by Chase,
which replaced U.S.  Trust as  the Fund's domestic  custodian. Chase  is not  an
affiliate  of  the Adviser  or the  Distributor.  Morgan Stanley  Trust Company,
Brooklyn, New York ("MSTC"),  an affiliate of the  Adviser and the  Distributor,
acts  as the Fund's custodian for foreign  assets held outside the United States
and employs subcustodians  approved by  the Board of  Directors of  the Fund  in
accordance  with regulations of  the Securities and  Exchange Commission for the
purpose of providing  custodial services  for such  assets. MSTC  may also  hold
certain  domestic assets for  the Fund. For more  information on the custodians,
see "General Information -- Custody Arrangements" in the Statement of Additional
Information.
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
    Chase  Global   Funds  Services   Company,   73  Tremont   Street,   Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
 
INDEPENDENT ACCOUNTANTS
 
    Price  Waterhouse LLP  serves as  independent accountants  for the  Fund and
audits its annual financial statements.
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       48
<PAGE>
                                   APPENDIX A
                     DESCRIPTION OF CORPORATE BOND RATINGS
 
MOODY'S INVESTORS SERVICE CORPORATE BOND RATINGS:
 
    Aaa -- Bonds which  are rated Aaa  are judged to be  the best quality.  They
carry  the smallest degree of  investment risk and are  generally referred to as
"gilt-edge." Interest payments are protected by  a large or by an  exceptionally
stable  margin, and principal  is secure. While  the various protective elements
are likely to change,  such changes as  can be visualized  are most unlikely  to
impair the fundamentally strong position of such issues.
 
    Aa  -- Bonds  which are rated  Aa are  judged to be  of high  quality by all
standards. Together with the Aaa group they comprise what are generally known as
high grade bonds. They are  rated lower than the  best bonds because margins  of
protection may not be as large as in Aaa securities or fluctuation of protective
elements  may be  of greater  amplitude or there  may be  other elements present
which make the long-term risks appear somewhat larger than in Aaa securities.
 
    Moody's applies  numerical modifiers  1, 2  and 3  in the  Aa and  A  rating
categories.  The modifier 1 indicates that the security ranks at a higher end of
the rating category, modifier 2 indicates a mid-range rating and the modifier  3
indicates that the issue ranks at the lower end of the rating category.
 
    A  -- Bonds which  are rated A possess  many favorable investment attributes
and are  to be  considered as  upper medium  grade obligations.  Factors  giving
security  to principal and interest are  considered adequate but elements may be
present which suggest a susceptibility to impairment sometime in the future.
 
    Baa -- Bonds which are rated Baa are considered as medium grade obligations,
i.e., they are neither  highly protected nor  poorly secured. Interest  payments
and  principal security appear  adequate for the  present but certain protective
elements may be lacking or may  be characteristically unreliable over any  great
length  of time. Such  bonds lack outstanding  investment characteristics and in
fact have speculative characteristics as well.
 
    Ba -- Bonds  which are  rated Ba are  judged to  have speculative  elements;
their  future  cannot be  considered as  well assured.  Often the  protection of
interest and  principal payments  may be  very moderate,  and thereby  not  well
safeguarded  during  both good  and bad  times over  the future.  Uncertainty of
position characterizes bonds in this class.
 
   
    B -- Bonds which are rated B generally lack characteristics of the desirable
investment. Assurance of interest  and principal payments  or of maintenance  of
other terms of the contract over any long period of time may be small.
    
 
    Caa -- Bonds which are rated Caa are of poor standing. Such issues may be in
default  or there may be present elements of danger with respect to principal or
interest.
 
    Ca -- Bonds which are rated  Ca represent obligations which are  speculative
in  a  high  degree. Such  issues  are often  in  default or  have  other marked
shortcomings.
 
    C -- Bonds which are rated C are the lowest rated class of bonds, and issues
so rated can be  regarded as having extremely  poor prospects of ever  attaining
any real investment standing.
 
                                       49
<PAGE>
STANDARD & POOR'S RATINGS GROUP CORPORATE BOND RATINGS:
 
    AAA -- Bonds rated AAA have the highest rating assigned by Standard & Poor's
to  a debt obligation and indicate an extremely strong capacity to pay principal
and interest.
 
    AA -- Bonds rated AA have a  very strong capacity to pay interest and  repay
principal and differ from the highest rated issues only to a small degree.
 
    A  --  Bonds  rated A  have  a strong  capacity  to pay  interest  and repay
principal although they are somewhat more susceptible to the adverse effects  of
changes  in circumstances  and economic  conditions than  bonds in  higher rated
categories.
 
    BBB -- Debt  rated BBB is  regarded as  having an adequate  capacity to  pay
interest  and repay principal. Whereas  it normally exhibits adequate protection
parameters, adverse  economic  conditions  or changing  circumstances  are  more
likely  to lead to a  weakened capacity to pay  interest and repay principal for
debt in this category than for debt in higher rated categories.
 
    BB, B, CCC, CC -- Debt rated BB,  B, CCC and CC is regarded, on balance,  as
predominantly  speculative with  respect to capacity  to pay  interest and repay
principal in  accordance with  the terms  of the  obligation. BB  indicates  the
lowest  degree of  speculation and CC  the highest degree  of speculation. While
such debt will likely  have some quality  and protective characteristics,  these
are  outweighed  by  large  uncertainties or  major  risk  exposures  to adverse
conditions.
 
    C -- The rating C is reserved for income bonds on which no interest is being
paid.
 
    D -- Debt rated D is in default, and payment of interest and/or repayment of
principal is in arrears.
 
                                       50
<PAGE>
<TABLE>
<CAPTION>
   MORGAN STANLEY INSTITUTIONAL FUND, INC.
          FIXED INCOME, GLOBAL FIXED INCOME, MORTGAGE-BACKED SECURITIES, 
          MUNICIPAL BOND, HIGH YIELD, MONEY MARKET AND MUNICIPAL MONEY MARKET 
          PORTFOLIOS
          P.O. BOX 2798, BOSTON, MA 02208-2798
   
- ---------------------------------------------------------------------------------------------------------------
    
    NOTE: THIS REGISTRATION FORM SHOULD BE COMPLETED BY THOSE INVESTORS WITH 
          EXISTING MORGAN STANLEY ACCOUNTS DESIRING TO INVEST FREE CASH BALANCES
          AUTOMATICALLY.


- ---------------------------------------------------------------------------------------------------------------

                                      ACCOUNT REGISTRATION FORM

- ---------------------------------------------------------------------------------------------------------------

<S>                        <C>
ACCOUNT INFORMATION        If you need assistance in filling out this form     
Fill in where applicable   for the Morgan Stanley Institutional Fund, please   
                           contact your Morgan Stanley representative or call  
                           us toll free 1-(800)-548-7786. Please print all     
                           items except signature, and mail to the Fund at the
                           address above.

- ---------------------------------------------------------------------------------------------------------------

A)  REGISTRATION
    1. INDIVIDUAL            1. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
                                 First Name           Initial              Last Name
    2. JOINT TENANTS         2. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       (RIGHTS OF                First Name           Initial              Last Name
       SURVIVORSHIP             / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       PRESUMED UNLESS           First Name           Initial              Last Name
       TENANCY IN COMMON
       IS INDICATED)
- ---------------------------------------------------------------------------------------------------------------

    3. CORPORATIONS,         3. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       TRUSTS AND OTHERS       
       Please call the          / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       Fund for additional
       documents that may       / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       be required to set 
       up account and to 
       authorize transactions.
                 Type of / / INCORPORATED / / UNINCORPORATED / / PARTNERSHIP / / UNIFORM GIFT/TRANSFER TO MINOR 
                 Registration:                 ASSOCIATION                   (ONLY ONE CUSTODIAN AND MINOR PERMITTED)


                                / / TRUST __________________________________     / / OTHER (Specify) ____________________________
- ---------------------------------------------------------------------------------------------------------------

B)  MAILING ADDRESS         Street or P.O. Box / / / / / / / / / / / / / / / / / / / / / / / / / / / /

    Please fill in 
    completely, including   City / / / / / / / / / / / / / State / / / Zip / / / / / /-/ / / / /  
    telephone number(s).
                            Home                                   Business
                            Telephone No./ / / /-/ / / /-/ / / / / Telephone No./ / / /-/ / / /-/ / / /
                            / / United States  / / Resident  / /Non-Resident Alien:
                                Citizen            Alien        Indicate Country of Residence _________

- ---------------------------------------------------------------------------------------------------------------

C)  TAXPAYER                    PART 1. Enter your Taxpayer             IMPORTANT TAX INFORMATION                      
    IDENTIFICATION               Identification Number. For most           You (as a payee) are required by            
    NUMBER                       individual taxpayers, this is your      law to provide us (as payer) with             
    If the account is in         Social Security Number.                 your correct taxpayer identification          
    more than one name,          TAXPAYER IDENTIFICATION NUMBER          number. Accounts that have a missing          
    CIRCLE THE NAME OF THE        / / / /-/ / / / / / / / /              or incorrect taxpayer identification          
    PERSON WHOSE TAXPAYER                   OR                           number will be subject to backup              
    IDENTIFICATION NUMBER           SOCIAL SECURITY NUMBER               withholding at a 31% rate on interest,        
    IS PROVIDED IN SECTION        / / / /-/ / /-/ / / / /                dividends, distributions and other            
    A) ABOVE. If no name        PART 2. BACKUP WITHHOLDING               payments. If you have not provided us with    
    is circled, the number        / / Check this box if you are          your correct taxpayer identification          
    will be considered to be      NOT subject to Backup                  number, you may be subject to                 
    that of the last name         Withholding under the                  a $50 penalty imposed by the Internal         
    listed. For Custodian         provisions of Section                  Revenue Service.                              
    account of a minor            3406(a)(1)(C) of the Internal            Backup withholding is not an                
    (Uniform Gifts/Transfers      Revenue Code.                          additional tax; the tax liability of          
    to Minor Acts), give the                                             persons subject to backup withholding         
    Social Security Number                                               will be reduced by the amount of tax          
    of the minor.                                                        withheld. If withholding results in           
                                                                         an overpayment of taxes, a refund             
                                                                         may be obtained.                              
                                                                           You may be notified                         
                                                                         that you are subject to backup                
                                                                         withholding under section 3406(a)(1)(C)       
                                                                         of the Internal Revenue Code because you      
                                                                         have underreported interest or dividends      
                                                                         or you were required to but failed to         
                                                                         file a return which would have included a     
                                                                         reportable interest or dividend payment. IF   
                                                                         YOU HAVE NOT BEEN SO NOTIFIED, CHECK THE      
                                                                         BOX IN PART 2 AT LEFT.                        

- ---------------------------------------------------------------------------------------------------------------

D)  PORTFOLIO AND          For Purchase of the following Portfolio(s):     
    CLASS SELECTION        Fixed Income Portfolio                       / / Class A Shares $____   / / Class B Shares $____
    (Class A shares        Global Fixed Income Portfolio                / / Class A Shares $____   / / Class B Shares $____
    minimum $500,000       Mortgage-Backed Securities Portfolio         / / Class A Shares $____   / / Class B Shares $____
    for each Portfolio     Municipal Bond Portfolio                     / / Class A Shares $____   / / Class B Shares $____
    and Class B shares     High Yield Portfolio                         / / Class A Shares $____   / / Class B Shares $____
    minimum $100,000 for   Money Market Portfolio                       / / Class A Shares $____  
    each of the Fixed      Municipal Money Market Portfolio             / / Class A Shares $____ 
    Income, Global Fixed
    Income, Municipal Bond,                                             Total Initial Investment $_____________
    Mortgage-Backed
    Securities and High
    Yield Portfolios.
    Minimum $50,000 for
    each of the Money
    Market and Municipal
    Money Market Portfolios.)
    Please indicate
    Portfolio, class and
    amount.

- ---------------------------------------------------------------------------------------------------------------
   
E)  METHOD OF   Payment by:
    INVESTMENT  / / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND, INC.--PORTFOLIO NAME)
    Please
    indicate
    portfolio,  / / Exchange $_______________________  From ______________________________         / / / / / / / / / / /-/ /
    manner of                                                     Name of Portfolio                      Account No.
    payment.

                / / Account previously established by:

               / / Phone exchange / / Wire on ________________________________                     / / / / / / / / / / / /-/ /
                                                                      Date                          Account No.            (Check
                                                                                          (Previously assigned by the Fund) Digit)
    

 
<PAGE>

- ---------------------------------------------------------------------------------------------------------------

   
F)  AUTHORIZATION OF AUTOMATIC                         I/we hereby authorize the Fund and Morgan Stanley Asset 
    PURCHASE AND REDEMPTION                            Management Inc. to transfer from my/our account at Morgan
    (Available only for Money                          Stanley & Co. Inc. all free cash balances (that is, any cash
    Market and Municipal Money                         available on demand at the close of the previous day), which
    Market Portfolios)                                 are held in such account and to invest such cash balances in
                                                       the / / Money Market Portfolio or the / / Municipal Money Market 
                                                       Portfolio (check only one).

                                                       ____________-________________________________   / / / / / / / / / / / - / /
                                                       Account Title at Morgan Stanley & Co. Inc.            Account Number
                                                       Account Number
    

- ---------------------------------------------------------------------------------------------------------------

G)  DISTRIBUTION                                       Income dividends and capital gains distributions (if any) will
    OPTION                                             be reinvested in additional shares unless either box below is
                                                       checked.

                                                       / / Income dividends to be paid in cash, capital
                                                           gains distributions (if any) in shares.

                                                       / /  Income dividends and capital gains distributions
                                                            (if any) to be paid in cash.

- ---------------------------------------------------------------------------------------------------------------


H)  TELEPHONE                    / / I/we hereby authorize the Fund and its      ______________________   ________________
    REDEMPTION                       agents to honor any telephone requests      Name of COMMERCIAL Bank  Bank Account No.
    Please select at time of         to wire redemption proceeds to the            (Not Savings Bank)
    initial application if you       commercial bank indicated at right and/or 
    wish to redeem shares by         mail redemption proceeds to the name and                             ________________
    telephone. A SIGNATURE           address in which my/our fund account is                                 Bank ABA No.
    GUARANTEE IS REQUIRED IF         registered if such requests are believed 
    BANK ACCOUNT IS NOT              to be authentic.                            _________________________________________________
    REGISTERED IDENTICALLY TO    TELEPHONE REQUESTS FOR REDEMPTIONS OR EXCHANGES Name(s) in which your BANK Account is Established
    YOUR FUND ACCOUNT.           WILL NOT BE HONORED UNLESS THE BOX IS CHECKED.
                                 THE FUND AND THE FUND'S TRANSFER AGENT WILL   
    TELEPHONE REQUESTS FOR       EMPLOY REASONABLE PROCEDURES TO CONFIRM THAT    _________________________________________________
    REDEMPTIONS OR EXCHANGES     INSTRUCTIONS COMMUNICATED BY TELEPHONE ARE                 Bank's Street Address
    WILL NOT BE HONORED          GENUINE. THESE PROCEDURES INCLUDE REQUIRING   
    UNLESS THE BOX AT RIGHT      THE INVESTOR TO PROVIDE CERTAIN PERSONAL      
    IS CHECKED.                  IDENTIFICATION INFORMATION AT THE TIME AN       _________________________________________________
                                 ACCOUNT IS OPENED AND PRIOR TO EFFECTING EACH   City                    State                Zip
                                 TRANSACTION REQUESTED BY TELEPHONE. IN ADDITION,
                                 ALL TELEPHONE TRANSACTION REQUESTS WILL BE RECORDED
                                 AND INVESTORS MAY BE REQUIRED TO PROVIDE ADDITIONAL
                                 TELECOPIED WRITTEN INSTRUCTIONS OF TRANSACTION
                                 REQUESTS. NEITHER THE FUND NOR THE TRANSFER AGENT WILL
                                 BE RESPONSIBLE FOR ANY LOSS, LIABILITY, COST OR EXPENSE
                                 FOR FOLLOWING INSTRUCTIONS RECEIVED BY TELEPHONE THAT
                                 IT REASONABLY BELIEVES TO BE GENUINE.                  


- ---------------------------------------------------------------------------------------------------------------

I)  INTERESTED PARTY
    OPTION
    In addition to the account   _________________________________________________________________
    statement sent to my/our                                 Name
    registered address, I/we     _________________________________________________________________
    hereby authorize the fund    
    to mail duplicate            _________________________________________________________________
    statements to the name and                              Address
    address provided at right.
                                 _________________________________________________________________
                                  City                      State                     Zip Code

- ---------------------------------------------------------------------------------------------------------------

J)  DEALER 
    INFORMATION                  _______________________  _______________________________  ___________
                                 Representative Name          Representative No.             Branch No.

- ---------------------------------------------------------------------------------------------------------------

K)  SIGNATURE OF        The  undersigned  certify(ies) that I/we  have full  authority and legal
    ALL HOLDERS         capacity  to purchase and redeem shares of the Fund and affirm that I/we
    AND TAXPAYER        have received a current Prospectus  of the Morgan Stanley  Institutional
    CERTIFICATION       Fund,  Inc. and agree to  be bound by its  terms. UNDER THE PENALTIES OF
    Sign Here >         PERJURY, I/WE CERTIFY THAT THE INFORMATION PROVIDED IN SECTION C)
                        ABOVE IS TRUE, CORRECT AND COMPLETE.

                        (X)                                 (X)
                        __________________________________  ______________________________________
                        Signature                Date       Signature                  Date


- ---------------------------------------------------------------------------------------------------------------
</TABLE>

<PAGE>
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
 
  NO  DEALER, SALES  REPRESENTATIVE OR ANY  OTHER PERSON HAS  BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE  CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS  HAVING BEEN AUTHORIZED BY THE FUND  OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF  THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION  TO
ANY  PERSON TO WHOM  IT IS UNLAWFUL TO  MAKE SUCH OFFER  OR SOLICITATION IN SUCH
JURISDICTION.
 
                           --------------------------
 
                               TABLE OF CONTENTS
 
<TABLE>
<S>                                                 <C>
                                                    PAGE
                                                    ----
Fund Expenses.....................................    2
Financial Highlights..............................    5
Prospectus Summary................................   12
Investment Objectives and Policies................   16
Additional Investment Information.................   26
Investment Limitations............................   29
Management of the Fund............................   30
Purchase of Shares................................   33
Redemption of Shares..............................   38
Shareholder Services..............................   40
Valuation of Shares...............................   41
Performance Information...........................   42
Dividends and Capital Gains Distributions.........   43
Taxes.............................................   44
Portfolio Transactions............................   46
General Information...............................   47
Appendix A........................................   49
Account Registration Form
</TABLE>
 
                             FIXED INCOME PORTFOLIO
                         GLOBAL FIXED INCOME PORTFOLIO
                            MUNICIPAL BOND PORTFOLIO
                      MORTGAGE-BACKED SECURITIES PORTFOLIO
                              HIGH YIELD PORTFOLIO
                             MONEY MARKET PORTFOLIO
                        MUNICIPAL MONEY MARKET PORTFOLIO
 
                               PORTFOLIOS OF THE
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
 
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
                      P.O. Box 2798, Boston, MA 02208-2798
 
- ---------------------------------
- ---------------------------------
- ---------------------------------
- ---------------------------------
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
     ----------------------------------------------------------------------
                        SMALL CAP VALUE EQUITY PORTFOLIO
                             VALUE EQUITY PORTFOLIO
                               BALANCED PORTFOLIO
                               PORTFOLIOS OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
                                ----------------
   
    Morgan  Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company, or mutual fund, which offers redeemable shares in
a   series   of   diversified   and   non-diversified   investment    portfolios
("portfolios").   The  Fund   currently  consists   of  twenty-eight  portfolios
representing a  broad range  of  investment choices.  The  Fund is  designed  to
provide clients with attractive alternatives for meeting their investment needs.
This  prospectus (the  "Prospectus") pertains  to the  Class A  and the  Class B
shares of the Small Cap Value  Equity Portfolio, the Value Equity Portfolio  and
the  Balanced Portfolio (the  "Portfolios"). On January  2, 1996, the Portfolios
began offering two classes of shares, the Class A shares and the Class B shares,
except for the Money Market, Municipal Money Market and International Small  Cap
Portfolios  which only offer Class A shares.  All shares of the Portfolios owned
prior to January 2, 1996  were redesignated Class A  shares on January 2,  1996.
The  Class  A  and Class  B  shares  currently offered  by  the  Portfolios have
different minimum  investment  requirements and  fund  expenses. Shares  of  the
portfolios  are offered with no sales charge or exchange or redemption fee (with
the exception of the International Small Cap Portfolio).
    
    The SMALL CAP VALUE  EQUITY PORTFOLIO seeks high  long-term total return  by
investing   in  undervalued   equity  securities   of  small-   to  medium-sized
corporations.
    The VALUE EQUITY PORTFOLIO  seeks high total return  by investing in  equity
securities  which the Adviser  believes to be undervalued  relative to the stock
market in general at the time of purchase.
    The BALANCED PORTFOLIO seeks high  total return while preserving capital  by
investing  in a  combination of undervalued  equity securities  and fixed income
securities.
    The Fund is designed  to meet the investment  needs of discerning  investors
who  place a premium on quality and  personal service. With Morgan Stanley Asset
Management  Inc.  as   Adviser  and   Administrator  (the   "Adviser"  and   the
"Administrator"),  and with Morgan Stanley & Co. Incorporated ("Morgan Stanley")
as Distributor, the Fund makes available to institutional investors and high net
worth individual  investors  a  series  of portfolios  which  benefit  from  the
investment expertise and commitment to excellence associated with Morgan Stanley
and its Affiliates.
   
    This Prospectus is designed to set forth concisely the information about the
Fund  that a prospective investor should know  before investing and it should be
retained for future reference. The Fund  also offers other portfolios which  are
described  in other prospectuses and under  "Prospectus Summary" below. The Fund
currently offers the following portfolios:  (i) GLOBAL AND INTERNATIONAL  EQUITY
- --  Active Country Allocation, Asian  Equity, Emerging Markets, European Equity,
Global Equity, Gold, International  Equity, International Magnum,  International
Small  Cap, Japanese Equity  and Latin American Portfolios;  (ii) U.S. EQUITY --
Aggressive Equity, Emerging  Growth, Equity  Growth, MicroCap,  Small Cap  Value
Equity,  U.S. Real  Estate and Value  Equity Portfolios; (iii)  EQUITY AND FIXED
INCOME -- Balanced Portfolio; (iv) FIXED INCOME -- Emerging Markets Debt,  Fixed
Income,   Global  Fixed  Income,  High  Yield,  Mortgage-Backed  Securities  and
Municipal Bond Portfolios; and  (v) MONEY MARKET --  Money Market and  Municipal
Money Market Portfolios. Additional information about the Fund is contained in a
"Statement  of Additional Information", dated May 1, 1996, which is incorporated
herein  by  reference.   The  Statement  of   Additional  Information  and   the
prospectuses  pertaining to the other portfolios  of the Fund are available upon
request and without charge  by writing or  calling the Fund  at the address  and
telephone number set forth above.
    
  THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES AND
 EXCHANGE COMMISSION OR ANY STATE SECURITIES COMMISSION, NOR HAS THE SECURITIES
   AND EXCHANGE COMMISSION OR ANY STATE SECURITIES COMMISSION PASSED UPON THE
          ACCURACY OR ADEQUACY OF THIS PROSPECTUS. ANY REPRESENTATION
                     TO THE CONTRARY IS A CRIMINAL OFFENSE.
 
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1996.
<PAGE>
                                 FUND EXPENSES
 
    The  following table illustrates the expenses and fees that a shareholder of
each Portfolio will incur:
 
   
<TABLE>
<CAPTION>
                                                              SMALL CAP VALUE   VALUE EQUITY    BALANCED
SHAREHOLDER TRANSACTION EXPENSES                             EQUITY PORTFOLIO     PORTFOLIO     PORTFOLIO
- -----------------------------------------------------------  -----------------  -------------  -----------
<S>                                                          <C>                <C>            <C>
Maximum Sales Load Imposed on Purchases
  Class A..................................................           None             None          None
  Class B..................................................           None             None          None
Maximum Sales Load Imposed on Reinvested Dividends
  Class A..................................................           None             None          None
  Class B..................................................           None             None          None
Deferred Sales Load
  Class A..................................................           None             None          None
  Class B..................................................           None             None          None
Redemption Fees
  Class A..................................................           None             None          None
  Class B..................................................           None             None          None
Exchange Fees
  Class A..................................................           None             None          None
  Class B..................................................           None             None          None
</TABLE>
    
   
<TABLE>
<CAPTION>
              ANNUAL FUND OPERATING EXPENSES
<S>                                                          <C>                <C>            <C>
- -----------------------------------------------------------
 
<CAPTION>
                                                              SMALL CAP VALUE   VALUE EQUITY    BALANCED
(AS A PERCENTAGE OF AVERAGE NET ASSETS)                      EQUITY PORTFOLIO     PORTFOLIO     PORTFOLIO
                                                             -----------------  -------------  -----------
<S>                                                          <C>                <C>            <C>
Management Fee (Net of Fee Waivers)*
  Class A..................................................          0.64%            0.43%         0.18%
  Class B..................................................          0.64%            0.43%         0.18%
12b-1 Fees
  Class A..................................................           None             None          None
  Class B..................................................          0.25%            0.25%         0.25%
Other Expenses
  Class A..................................................          0.36%            0.27%         0.52%
  Class B..................................................          0.36%            0.27%         0.52%
                                                                    ------           ------    -----------
Total Operating Expenses (Net of Fee Waivers)*
  Class A..................................................          1.00%            0.70%         0.70%
  Class B..................................................          1.25%            0.95%         0.95%
                                                                    ------           ------    -----------
                                                                    ------           ------    -----------
</TABLE>
    
 
- ------------------------
   
*The Adviser  has agreed  to  waive its  management  fee and/or  reimburse  each
 Portfolio,  if necessary, if  such fees would cause  the total annual operating
 expenses of the Portfolios to exceed a specified percentage of their respective
 average daily  net  assets.  Set  forth below,  for  each  Portfolio,  are  the
 management fees absent fee waivers and total operating expenses absent such fee
 waivers  and/or reimbursements as a percent of  the average daily net assets of
 the Class A shares and Class B shares, respectively.
    
 
                                       2
<PAGE>
 
   
<TABLE>
<CAPTION>
                                                                                        TOTAL OPERATING EXPENSES
                                                                                           ABSENT FEE WAIVERS
                                                                   MANAGEMENT FEE      --------------------------
PORTFOLIO                                                        ABSENT FEE WAIVERS      CLASS A       CLASS B+
- --------------------------------------------------------------  ---------------------  ------------  ------------
<S>                                                             <C>                    <C>           <C>
Small Cap Value Equity........................................            0.85%              1.21%         1.46%
Value Equity..................................................            0.50%              0.77%         1.02%
Balanced......................................................            0.50%              1.02%         1.27%
</TABLE>
    
 
- ------------------------------
   
+  Estimated.
    
 
    As a result of these reductions, the Management Fees stated above are  lower
than  the contractual  fees stated under  "Management of the  Fund." The Adviser
reserves  the  right  to  terminate  any  of  its  fee  waivers  and/or  expense
reimbursements  at any time  in its sole discretion.  For further information on
Fund expenses, see "Management of the Fund."
 
   
    The purpose of the  table above is to  assist the investor in  understanding
the  various expenses that an  investor in the Portfolios  will bear directly or
indirectly. The Class A expenses and fees for each Portfolio are based on actual
figures for the fiscal year  ended December 31, 1995.  The Class B expenses  and
fees  for the Portfolios are based on estimates, assuming that the average daily
net assets of the Class B shares  of each Portfolio will be $50,000,000.  "Other
Expenses"  include  Board  of  Directors'  fees  and  expenses,  amortization of
organizational costs, filing fees, professional  fees and costs for  shareholder
reports.  Due to  the continuous nature  of Rule  12b-1 fees, long  term Class B
shareholders may pay  more than the  equivalent of the  maximum front-end  sales
charges  otherwise  permitted by  the  Rules of  Fair  Practice of  the National
Association of Securities Dealers, Inc. ("NASD").
    
 
    The following  example illustrates  the expenses  that you  would pay  on  a
$1,000  investment assuming (1) a 5% annual rate of return and (2) redemption at
the end of each time period. As noted in the table above, the Portfolios  charge
no  redemption  fees  of any  kind.  The  following example  is  based  on total
operating expenses of the Portfolios after fee waivers.
 
<TABLE>
<CAPTION>
                                                                       1 YEAR       3 YEARS      5 YEARS     10 YEARS
                                                                     -----------  -----------  -----------  -----------
<S>                                                                  <C>          <C>          <C>          <C>
Small Cap Value Equity Portfolio
  Class A..........................................................   $      10    $      32    $      55    $     122
  Class B..........................................................          13           40           69          151
Value Equity Portfolio
  Class A..........................................................           7           22           39           87
  Class B..........................................................          10           30           53          117
Balanced Portfolio
  Class A..........................................................           7           22           39           87
  Class B..........................................................          10           30           53          117
</TABLE>
 
    THIS EXAMPLE SHOULD  NOT BE CONSIDERED  A REPRESENTATION OF  PAST OR  FUTURE
EXPENSES  OR  PERFORMANCE. ACTUAL  EXPENSES MAY  BE GREATER  OR LESS  THAN THOSE
SHOWN.
 
    The Fund intends  to comply  with all  state laws  that restrict  investment
company  expenses. Currently, the  most restrictive state  law requires that the
aggregate annual expenses  of an  investment company  shall not  exceed two  and
one-half  percent (2 1/2%) of  the first $30 million  of average net assets, two
percent (2%) of the next $70 million of average net assets, and one and one-half
percent (1 1/2%) of the remaining net assets of such investment company.
 
    The Adviser has agreed to a reduction  in the amounts payable to it, and  to
reimburse  any Portfolio,  if necessary, if  in any  fiscal year the  sum of the
Portfolio's expenses exceeds the limit set by applicable state laws.
 
                                       3
<PAGE>
                              FINANCIAL HIGHLIGHTS
 
   
    The following tables provide financial highlights for the Class A shares for
each of  the  Portfolios  for  the  periods  presented.  The  audited  financial
highlights  for the Class A  shares for the fiscal  year ended December 31, 1995
are part of the Fund's financial statements which appear in the Fund's  December
31,  1995  Annual  Report  to  Shareholders which  are  included  in  the Fund's
Statement of Additional  Information. The Portfolio's  financial highlights  for
each  of the periods in the five years ended December 31, 1995 have been audited
by Price Waterhouse LLP,  whose unqualified report thereon  is also included  in
the  Statement of Additional Information. Additional performance information for
the Class A shares is included in  the Annual Report. The Annual Report and  the
financial   statements  therein,   along  with   the  Statement   of  Additional
Information, are available at no cost from the Fund at the address and telephone
number noted on the cover page of this Prospectus. Financial Highlights are  not
available  for the new Class B shares since they were not offered as of December
31, 1995. Subsequent to October 31, 1992 (the Fund's prior fiscal year end)  the
Fund  changed  its fiscal  year end  to December  31. The  following information
should be read in conjunction with the financial statements and notes thereto.
    
 
                                       4
<PAGE>
                        SMALL CAP VALUE EQUITY PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                          DECEMBER 17,
                                            1992* TO      YEAR ENDED     YEAR ENDED     YEAR ENDED
                                          DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,
                                              1992           1993           1994           1995
                                          ------------   ------------   ------------   ------------
<S>                                       <C>            <C>            <C>            <C>
NET ASSET VALUE, BEGINNING OF PERIOD....  $ 10.00        $ 10.14        $ 11.10        $ 10.80
                                           ------        ------------   ------------   ------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)(2)..........     0.01           0.24           0.28           0.30
  Net Realized and Unrealized
   Gain/(Loss) on Investments...........     0.13           0.90          (0.01)          1.82
                                           ------        ------------   ------------   ------------
  Total from Investment Operations......     0.14           1.14           0.27           2.12
                                           ------        ------------   ------------   ------------
DISTRIBUTIONS
  Net Investment Income.................       --          (0.18)         (0.27)         (0.38)
  Net Realized Gain.....................       --             --          (0.30)         (0.63)
                                           ------        ------------   ------------   ------------
TOTAL DISTRIBUTIONS.....................       --          (0.18)         (0.57)         (1.01)
                                           ------        ------------   ------------   ------------
NET ASSET VALUE, END OF PERIOD..........  $ 10.14        $ 11.10        $ 10.80        $ 11.91
                                           ------        ------------   ------------   ------------
                                           ------        ------------   ------------   ------------
TOTAL RETURN............................     1.40%         11.33%          2.53%         20.63%
                                           ------        ------------   ------------   ------------
                                           ------        ------------   ------------   ------------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)...  $ 5,974        $26,775        $40,033        $51,919
Ratio of Expenses to Average Net
 Assets (1)(2)..........................     1.00%**        1.00%          1.00%          1.00%
Ratio of Net Investment Income to
 Average Net Assets (1)(2)..............     1.64%**        2.56%          2.67%          2.60%
Portfolio Turnover Rate.................        0%            29%            22%            36%
</TABLE>
    
 
- ------------------------------
 
<TABLE>
<S> <C>                                   <C>            <C>            <C>            <C>
(1) Effect of voluntary expense limitation during the
     period:
    Per share benefit to net investment
     income.............................  $     0.13     $     0.06     $     0.03     $     0.02
    Ratios before expense limitation:
    Expenses to Average Net Assets......       23.14  %**       1.68  %       1.26  %        1.21  %
    Net Investment Income (Loss) to
     Average Net Assets.................      (20.50  )%**       1.88  %       2.41  %       2.39  %
</TABLE>
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to receive a management  fee calculated at  an annual rate  of 0.85% of  the
    average  daily  net assets  of  the Small  Cap  Value Equity  Portfolio. The
    Adviser has agreed to waive a portion of this fee and/ or reimburse expenses
    of the Portfolio  to the  extent that the  total operating  expenses of  the
    Portfolio exceed 1.00% of the average daily net assets of the Class A shares
    and  1.25% of  the average daily  net assets of  the Class B  shares. In the
    period ended December 31, 1992, the years ended December 31, 1993, 1994  and
    1995,   the  Adviser  waived  management  fees  and/or  reimbursed  expenses
    totalling $38,000,  $123,000, $94,000  and  $97,000, respectively,  for  the
    Small Cap Value Equity Portfolio.
    
 
 * Commencement of Operations.
 
** Annualized.
 
                                       5
<PAGE>
                             VALUE EQUITY PORTFOLIO
 
   
<TABLE>
<CAPTION>
                         JANUARY 31,                             TWO MONTHS
                           1990* TO    YEAR ENDED   YEAR ENDED     ENDED      YEAR ENDED   YEAR ENDED   YEAR ENDED
                         OCTOBER 31,  OCTOBER 31,  OCTOBER 31,  DECEMBER 31, DECEMBER 31, DECEMBER 31, DECEMBER 31,
                             1990         1991         1992         1992         1993         1994         1995
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
<S>                      <C>          <C>          <C>          <C>          <C>          <C>          <C>
NET ASSET VALUE,
 BEGINNING OF PERIOD..... $ 10.00     $  8.59      $ 10.24      $ 10.71      $ 11.31      $ 12.63      $ 11.50
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment
   Income (1)(2).........    0.37        0.46         0.38         0.08         0.37         0.40         0.38
  Net Realized and
   Unrealized Gain/(Loss)
   on investments........   (1.45)       1.67         0.48         0.52         1.31        (0.55)        3.30
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
  Total from Investment
   Operations............   (1.08)       2.13         0.86         0.60         1.68        (0.15)        3.68
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
DISTRIBUTIONS
  Net Investment
   Income................   (0.33)      (0.48)       (0.39)          --        (0.36)       (0.40)       (0.47)
  Net Realized Gain......      --          --           --           --           --        (0.58)       (0.77)
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
TOTAL DISTRIBUTIONS......   (0.33)      (0.48)       (0.39)          --        (0.36)       (0.98)       (1.24)
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
NET ASSET VALUE, END OF
 PERIOD.................. $  8.59     $ 10.24      $ 10.71      $ 11.31      $ 12.63      $ 11.50      $ 13.94
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
TOTAL RETURN.............  (11.05)%     25.34%        8.51%        5.60%       15.14%       (1.29)%      33.69%
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
RATIOS AND SUPPLEMENTAL
 DATA:
Net Assets, End of Period
 (Thousands)............. $18,178     $16,304      $25,013      $27,541      $54,598      $73,406      $147,365
Ratio of Expenses to
 Average Net
 Assets (1)(2)...........    0.70%**     0.70%        0.70%        0.70%**      0.70%        0.70%        0.70%
Ratio of Net Investment
 Income to Average Net
 Assets (1)(2)...........    5.46%**     4.57%        3.72%        4.41%**      3.23%        3.37%        3.01%
Portfolio Turnover
 Rate....................      70%         90%          56%           9%          51%          33%          43%
</TABLE>
    
 
- ------------------------------
 
<TABLE>
<S> <C>                  <C>          <C>          <C>          <C>          <C>          <C>          <C>
(1) Effect of voluntary expense limitation
     during the period:
    Per share benefit to
     net
       investment
     income.............. $      0.01 $      0.02  $      0.01  $     0.01   $     0.03   $     0.01   $      0.01
    Ratios before expense limitation:
    Expenses to Average
     Net
       Assets............        0.88  **        0.87 %        0.84 %       1.20   **       0.95  %       0.80  %        0.77 %
    Net Investment Income
     to
       Average Net
     Assets..............        5.28  **        4.40 %        3.58 %       3.91   **       2.98  %       3.27  %        2.94 %
</TABLE>
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to  receive a management  fee calculated at  an annual rate  of 0.50% of the
    average daily net  assets of  the Value  Equity Portfolio.  The Adviser  has
    agreed  to waive  a portion  of this  fee and/or  reimburse expenses  of the
    Portfolio to the extent that the  total operating expenses of the  Portfolio
    exceed 0.70% of the average daily net assets of the Class A shares and 0.95%
    of  the average daily net assets of the  Class B shares. In the period ended
    October 31, 1990, the years ended October 31, 1991 and 1992, the two  months
    ended  December 31, 1992, the years ended  December 31, 1993, 1994 and 1995,
    the Adviser  waived management  fees  and/or reimbursed  expenses  totalling
    $26,000,   $25,000,  $27,000,   $24,000,  $106,000,   $73,000  and  $85,000,
    respectively, for the Value Equity Portfolio.
    
 
 * Commencement of Operations.
 
** Annualized.
 
                                       6
<PAGE>
                               BALANCED PORTFOLIO
 
   
<TABLE>
<CAPTION>
                         FEBRUARY 20,                            TWO MONTHS
                           1990* TO    YEAR ENDED   YEAR ENDED     ENDED      YEAR ENDED   YEAR ENDED   YEAR ENDED
                         OCTOBER 31,  OCTOBER 31,  OCTOBER 31,  DECEMBER 31, DECEMBER 31, DECEMBER 31, DECEMBER 31,
                             1990         1991         1992         1992         1993         1994         1995
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
<S>                      <C>          <C>          <C>          <C>          <C>          <C>          <C>
NET ASSET VALUE,
 BEGINNING OF PERIOD..... $   10.00   $    9.62    $   10.61    $   11.00    $   11.31    $   11.13    $    8.96
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment
   Income (1)(2).........      0.40        0.59         0.58         0.10         0.44         0.42         0.39
  Net Realized and
   Unrealized Gain (Loss)
   on Investments........     (0.46)       1.03         0.42         0.21         0.79        (0.64)        1.62
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
  Total from Investment
   Operations............     (0.06)       1.62         1.00         0.31         1.23        (0.22)        2.01
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
DISTRIBUTIONS
  Net Investment
   Income................     (0.32)      (0.63)       (0.58)          --        (0.41)       (0.49)       (0.50)
  In Excess of Net
   Investment Income.....        --          --           --           --        (0.08)          --           --
  Net Realized Gain......        --          --        (0.03)          --        (0.06)       (1.46)       (0.49)
  In Excess of Net
   Realized Gain.........        --          --           --           --        (0.86)          --           --
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
  Total Distributions....     (0.32)      (0.63)       (0.61)          --        (1.41)       (1.95)       (0.99)
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
NET ASSET VALUE, END OF
 PERIOD.................. $    9.62   $   10.61    $   11.00    $   11.31    $   11.13    $    8.96    $    9.98
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
TOTAL RETURN.............     (0.63)%     17.31%        9.57%        2.82%       12.09%       (2.32)%      23.63%
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period
 (Thousands)............. $  37,444   $  51,334    $  40,332    $  39,984    $  29,684    $  18,492    $  22,642
Ratio of Expenses to
 Average Net
 Assets (1)(2)...........      0.70%**      0.70%       0.70%        0.70%**      0.70%        0.70%        0.70%
Ratio of Net Investment
 Income to Average Net
 Assets (1)(2)...........      6.81%**      5.99%       5.21%        5.29%**      3.88%        4.13%        4.10%
Portfolio Turnover
 Rate....................        19%         67%          40%           4%         136%          44%          26%
</TABLE>
    
 
- ------------------------------
 
<TABLE>
<S>  <C>                 <C>          <C>          <C>          <C>          <C>          <C>          <C>
     Effect of voluntary expense
(1)   limitation during the period:
     Per share benefit to
      net
        investment
      income............. $    0.01   $    0.01    $    0.01    $    0.01    $    0.04    $    0.03    $    0.03
     Ratios before
      expense limitation:
     Expenses to Average
      Net
        Assets...........      0.90%**      0.78%       0.79%        1.00%**      1.02%        0.95%        1.02%
     Net Investment
      Income to
        Average Net
      Assets.............      6.61%**      5.91%       5.12%        4.99%**      3.56%        3.88%        3.78%
</TABLE>
 
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to receive a management  fee calculated at  an annual rate  of 0.50% of  the
    average  daily net assets of the  Balanced Portfolio. The Adviser has agreed
    to waive a portion of this fee and/or reimburse expenses of the Portfolio to
    the extent that the total operating  expenses of the Portfolio exceed  0.70%
    of  the average  daily net  assets of the  Class A  shares and  0.95% of the
    average daily net assets of the Class B shares. In the period ended  October
    31,  1990, the years ended  October 31, 1991 and  1992, the two months ended
    December 31, 1992,  the years ended  December 31, 1993,  1994 and 1995,  the
    Adviser waived management fees and/or reimbursed expenses totalling $38,000,
    $39,000,  $40,000, $20,000, $115,000, $60,000 and $68,000, respectively, for
    the Balanced Portfolio.
 
 * Commencement of Operations.
 
** Annualized.
 
                                       7
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
 
   
    The   Fund  consists  of  twenty-eight  portfolios,  offering  institutional
investors and high net  worth individual investors a  broad range of  investment
choices coupled with the advantages of a no-load mutual fund with Morgan Stanley
and  its affiliates providing customized  services as Adviser, Administrator and
Distributor. Each portfolio, offers Class A shares and, except the International
Small Cap, Money Market and Municipal Money Market Portfolios (the "Single Class
Portfolios"), also offers Class B shares. Each portfolio has its own  investment
objective and policies designed to meet specific goals. The investment objective
of each Portfolio described in this Prospectus is as follows:
    
 
   
    - The  SMALL CAP VALUE EQUITY PORTFOLIO seeks high long-term total return by
      investing in  undervalued  equity  securities of  small-  to  medium-sized
      corporations.
    
 
   
    - The  VALUE EQUITY PORTFOLIO seeks high total return by investing in equity
      securities which the Adviser  believes to be  undervalued relative to  the
      stock market in general at the time of purchase.
    
 
   
    - The BALANCED PORTFOLIO seeks high total return while preserving capital by
      investing  in  a combination  of undervalued  equity securities  and fixed
      income securities.
    
 
   
    The other portfolios of the Fund  are described in other Prospectuses  which
may be obtained from the Fund at the address and phone number noted on the cover
page  of this  Prospectus. The objectives  of these other  portfolios are listed
below:
    
 
   
    GLOBAL AND INTERNATIONAL EQUITY:
    
 
   
    - The  ACTIVE   COUNTRY  ALLOCATION   PORTFOLIO  seeks   long-term   capital
      appreciation by investing in accordance with country weightings determined
      by  the Adviser  in equity  securities of  non-U.S. issuers  which, in the
      aggregate, replicate broad country indices.
    
 
   
    - The  ASIAN  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
      investing primarily in equity securities of Asian issuers.
    
 
   
    - The CHINA GROWTH PORTFOLIO seeks to provide long-term capital appreciation
      by  investing primarily  in equity securities  of issuers  in The People's
      Republic of China, Hong Kong and Taiwan.
    
 
   
    - The EMERGING  MARKETS PORTFOLIO  seeks long-term  capital appreciation  by
      investing primarily in equity securities of emerging country issuers.
    
 
   
    - The  EUROPEAN  EQUITY PORTFOLIO  seeks  long-term capital  appreciation by
      investing primarily in equity securities of European issuers.
    
 
   
    - The GLOBAL  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
      investing  primarily in equity securities of issuers throughout the world,
      including United States issuers.
    
 
   
    - The GOLD  PORTFOLIO  seeks  long-term capital  appreciation  by  investing
      primarily  in equity securities of foreign and domestic issuers engaged in
      gold-related activities.
    
 
   
    - The INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of non-United States issuers.
    
 
                                       8
<PAGE>
   
    - The INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of non-U.S. issuers in accordance
      with EAFE  country (as  defined in  "Investment Objectives  and  Policies"
      below) weightings determined by the Adviser.
    
 
   
    - The INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital appreciation
      by  investing primarily in equity  securities of non-United States issuers
      with equity market capitalizations of less than $1 billion.
    
 
   
    - The JAPANESE  EQUITY PORTFOLIO  seeks  long-term capital  appreciation  by
      investing primarily in equity securities of Japanese issuers.
    
 
   
    - The  LATIN  AMERICAN  PORTFOLIO seeks  long-term  capital  appreciation by
      investing primarily in  equity securities  of Latin  American issuers  and
      debt  securities  issued or  guaranteed by  Latin American  governments or
      governmental entities.
    
 
   
    US EQUITY:
    
 
   
    - The AGGRESSIVE EQUITY  PORTFOLIO seeks capital  appreciation by  investing
      primarily in corporate equity and equity-linked securities.
    
 
   
    - The  EMERGING  GROWTH PORTFOLIO  seeks  long-term capital  appreciation by
      investing primarily  in growth-oriented  equity  securities of  small-  to
      medium-sized corporations.
    
 
   
    - The  EQUITY  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation by
      investing  in  growth-oriented  equity  securities  of  medium  and  large
      capitalization companies.
    
 
   
    - The  MICROCAP PORTFOLIO seeks long-term  capital appreciation by investing
      primarily in growth-oriented equity securities of small corporations.
    
 
   
    - The U.S.  REAL ESTATE  PORTFOLIO seeks  to provide  above average  current
      income and long-term capital appreciation by investing primarily in equity
      securities  of companies in the U.S.  real estate industry, including real
      estate investment trusts.
    
 
   
    FIXED INCOME:
    
 
   
    - The EMERGING MARKETS DEBT PORTFOLIO  seeks high total return by  investing
      primarily   in  debt  securities  of  government,  government-related  and
      corporate issuers located in emerging countries.
    
 
   
    - The FIXED INCOME PORTFOLIO seeks to produce a high total return consistent
      with the preservation of capital  by investing in a diversified  portfolio
      of fixed income securities.
    
 
   
    - The GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real rate
      of return while preserving capital by investing in fixed income securities
      of issuers throughout the world, including U.S. issuers.
    
 
   
    - The  HIGH YIELD PORTFOLIO seeks to maximize total return by investing in a
      diversified portfolio of high yield  fixed income securities that offer  a
      yield  above  that generally  available on  debt  securities in  the three
      highest rating categories of the recognized rating services.
    
 
   
    - The MORTGAGE-BACKED SECURITIES PORTFOLIO seeks to produce as high a  level
      of  current income  as is consistent  with the preservation  of capital by
      investing primarily  in  a  variety  of  investment-grade  mortgage-backed
      securities.
    
 
                                       9
<PAGE>
   
    - The  MUNICIPAL BOND  PORTFOLIO seeks  to produce  a high  level of current
      income consistent with  the preservation of  principal through  investment
      primarily  in municipal obligations, the interest  on which is exempt from
      federal income tax.
    
 
   
    MONEY MARKET:
    
 
   
    - The MONEY MARKET PORTFOLIO seeks  to maximize current income and  preserve
      capital  while maintaining high  levels of liquidity  through investing in
      high quality money  market instruments  with remaining  maturities of  one
      year or less.
    
 
   
    - The  MUNICIPAL MONEY MARKET PORTFOLIO seeks to maximize current tax-exempt
      income and preserve  capital while  maintaining high  levels of  liquidity
      through  investing in high quality money market instruments with remaining
      maturities of one year or less which are exempt from federal income tax.
    
 
   
INVESTMENT MANAGEMENT
    
 
   
    Morgan Stanley Asset Management  Inc., a wholly  owned subsidiary of  Morgan
Stanley  Group  Inc.,  which,  together  with  its  affiliated  asset management
companies, at December 31, 1995 had approximately $57.4 billion in assets  under
management  as  an  investment  manager  or  as  a  fiduciary  adviser,  acts as
investment adviser to the  Fund and each of  its Portfolios. See "Management  of
the Fund -- Investment Adviser" and "-- Administrator."
    
 
   
HOW TO INVEST
    
 
    Class  A shares of each  Portfolio are offered directly  to investors at net
asset value with no sales  commission or 12b-1 charges.  Class B shares of  each
Portfolio  are offered at net  asset value with no  sales commission, but with a
12b-1 fee, which  is accrued daily  and paid  quarterly, equal to  0.25% of  the
Class B shares' average daily net assets on an annualized basis. Share purchases
may  be  made  by  sending  investments directly  to  the  Fund  or  through the
Distributor. Shares  in a  Portfolio account  opened prior  to January  2,  1996
(each,  a "Pre-1996 Account") were designated Class A shares on January 2, 1996.
For a Portfolio account opened  on or after January  2, 1996 (a "New  Account"),
the  minimum initial investment is $500,000 for Class A shares of each Portfolio
and $100,000 for  Class B shares  of each Portfolio.  Certain exceptions to  the
foregoing  minimums apply to  (1) shares in  a Pre-1996 Account  with a value of
$100,000 or  more on  March 1,  1996 (a  "Grandfathered Class  A Account");  (2)
Portfolio  accounts held by officers of the  Adviser and its affiliates; and (3)
certain advisory or asset  allocation accounts, such  as Total Funds  Management
accounts,  managed by  Morgan Stanley or  its affiliates,  including the Adviser
("Managed Accounts"). The Adviser reserves the  right in its sole discretion  to
determine  which of such advisory or  asset allocation accounts shall be Managed
Accounts. For information regarding Managed Accounts please contact your  Morgan
Stanley  account representative or the Fund  at the telephone number provided on
the cover of this Prospectus. Shares in a Pre-1996 Account with a value of  less
than  $100,000 on March 1, 1996 (a "Grandfathered Class B Account") converted to
Class B shares on March 1, 1996. The minimum investment levels may be waived  at
the  discretion of the Adviser for (i) certain employees and customers of Morgan
Stanley or  its  affiliates and  certain  trust departments,  brokers,  dealers,
agents,  financial planners,  financial services  firms, or  investment advisers
that have entered into an agreement  with Morgan Stanley or its affiliates;  and
(ii)  retirement and  deferred compensation plans  and trusts used  to fund such
plans, including, but not limited to, those defined in Section 401(a), 403(b) or
457 of the Internal Revenue  Code of 1986, as  amended, and "rabbi trusts".  See
"Purchase  of Shares  -- Minimum Investment  and Account  Sizes; Conversion from
Class A to Class B Shares."
 
                                       10
<PAGE>
    The minimum  subsequent  investment for  each  Portfolio account  is  $1,000
(except  for automatic reinvestment of dividends and capital gains distributions
for which there is no minimum).  Such subsequent investments will be applied  to
purchase  additional  shares  in the  same  class  held by  a  shareholder  in a
Portfolio account. See "Purchase of Shares -- Additional Investments."
 
HOW TO REDEEM
 
   
    Class A shares or Class  B shares of each Portfolio  may be redeemed at  any
time, without cost, at the net asset value per share of shares of the applicable
class  next determined after  receipt of the  redemption request. The redemption
price may be more or less than the purchase price. Certain redemptions may cause
involuntary redemption or automatic conversion. Class  A or Class B shares  held
in   New  Accounts  are   subject  to  involuntary   redemption  if  shareholder
redemption(s) of such  shares reduces  the value of  such account  to less  than
$100,000  for a continuous 60-day period.  Involuntary redemption does not apply
to Managed Accounts, Grandfathered  Class A Accounts  and Grandfathered Class  B
Accounts,  regardless of  the value of  such accounts.  Class A shares  in a New
Account will convert  to Class  B shares  if shareholder  redemption(s) of  such
shares  reduces the value of such account to less than $500,000 for a continuous
60-day period. Class B shares in a New Account will convert to Class A shares if
shareholder purchases of additional Class B shares or market activity cause  the
value  of the Class B shares in the New Account to increase to $500,000 or more.
See "Purchase of Shares -- Minimum  Account Sizes and Involuntary Redemption  of
Shares" and "Redemption of Shares."
    
 
RISK FACTORS
 
   
    The  investment policies of each of  the Portfolios entail certain risks and
considerations of which an investor should  be aware. Each Portfolio may  invest
in   securities  of  foreign  issuers  and  forward  foreign  currency  exchange
contracts, which are subject to certain risks not typically associated with U.S.
securities. Because the Small  Cap Value Equity  Portfolio seeks high  long-term
total return by investing primarily in small- to medium-sized corporations which
are more vulnerable to financial risks and other risks than larger corporations,
investments  may  involve a  higher  degree of  risk  and price  volatility than
investments in  the  general  equity markets.  See  "Investment  Objectives  and
Policies"  and "Additional Investment Information."  In addition, each Portfolio
may invest in repurchase agreements, lend its portfolio securities and  purchase
securities  on  a when-issued  basis  or delayed  delivery  basis and  invest in
forward foreign currency  exchange contracts to  hedge currency risk  associated
with  investments in non-U.S. dollar-denominated  securities. The Portfolios may
also invest indirectly in securities  through sponsored or unsponsored  American
Depositary Receipts. Each Portfolio may invest in short-term or medium-term debt
securities  or hold cash  or cash equivalents  for temporary defensive purposes.
The Portfolios may  also invest in  stock options, stock  futures contracts  and
options on stock futures contracts. Each of these investment strategies involves
specific  risks which are  described under "Investment  Objectives and Policies"
and "Additional Investment Information" herein and under "Investment  Objectives
and Policies" in the Statement of Additional Information.
    
 
                                       11
<PAGE>
                       INVESTMENT OBJECTIVES AND POLICIES
 
    The investment objective of each Portfolio is described below, together with
the  policies the Fund employs in its  efforts to achieve these objectives. Each
Portfolio's investment  objective  is a  fundamental  policy which  may  not  be
changed without the approval of a majority of the Portfolio's outstanding voting
securities.  There is no assurance that the Fund will attain its objectives. The
investment policies  described below  are not  fundamental policies  and may  be
changed without shareholder approval.
 
THE SMALL CAP VALUE EQUITY PORTFOLIO
 
    The  investment  objective of  the Small  Cap Value  Equity Portfolio  is to
provide high  total  return by  investing  in  equity securities  of  small-  to
medium-sized  corporations that the Adviser  believes to be undervalued relative
to the stock market in  general at the time  of purchase. The Portfolio  invests
primarily   in   corporations  domiciled   in  the   U.S.  with   equity  market
capitalizations that range generally from $70 million up to $1 billion, but  may
from  time to  time invest  in similar  size foreign  corporations. Under normal
circumstances, the Portfolio will invest at least 65% of the value of its  total
assets  in equity securities of  corporations whose equity market capitalization
is up to $1  billion. The Portfolio  may invest up  to 35% of  the value of  its
total  assets in equity  securities of corporations  which are generally smaller
than the 500  largest corporations  in the United  States. With  respect to  the
Portfolio,  equity securities  include common and  preferred stocks, convertible
securities, rights and warrants  to purchase common  stocks, and similar  equity
interests, such as trusts or partnership interests. These investments may or may
not carry voting rights.
 
    The  Adviser invests  with the  philosophy that  a diversified  portfolio of
undervalued, small- to medium-sized companies will provide high total return  in
the long run.
 
    Companies considered attractive will have the following characteristics:
 
        1.   The market prices of the stocks will be undervalued relative to the
    normal earning power of the companies;
 
        2.  Stock  prices will be  low relative  to the intrinsic  value of  the
    companies' assets;
 
        3.   Stocks will most often have  yields distinctly above the average of
    companies with similar capitalizations; and
 
        4.   Stocks will  be of  high  quality, in  the Adviser's  judgment,  as
    evaluated  by the  companies' balance sheets,  income statements, franchises
    and product competitiveness.
 
    The thrust  of this  approach is  to seek  investments in  stocks for  which
investor enthusiasm is currently low, as reflected in their valuation, but which
have  the financial and fundamental features,  which, according to the Adviser's
assessment, will  allow the  stocks  to achieve  a  higher valuation.  Value  is
achieved  and  exposure  is  reduced  for  the  Portfolio  when  the  investment
community's perceptions  improve  and  the  stocks  approach  what  the  Adviser
believes is fair valuation.
 
    The  Adviser takes a long-term approach by  placing a strong emphasis on its
ability to identify attractive values. The Adviser does not intend to respond to
short-term   market   fluctuations   or   to   acquire   securities   for    the
 
                                       12
<PAGE>
purpose  of  short-term  trading. However,  the  Adviser may  take  advantage of
short-term opportunities that are  consistent with its  objective of high  total
return.  The Portfolio  will maintain  diversity among  industries and  does not
expect to invest more than 25% of its  total assets in the stocks of issuers  in
any one industry.
 
    The   Portfolio  invests  primarily  in  small-  to  medium-sized  companies
domiciled in  the  U.S.  The  portfolio  may,  on  occasion,  invest  in  equity
securities  of  foreign  issuers  that  trade on  a  United  States  exchange or
over-the-counter in the form of  American Depositary Receipts or common  stocks.
See "Additional Investment Information."
 
    Any remaining assets of the Portfolio not invested as described above may be
invested  in  certain  securities or  obligations  as set  forth  in "Additional
Investment Information" below.
 
THE VALUE EQUITY PORTFOLIO
 
    The investment objective of  the Value Equity Portfolio  is to achieve  high
total  return (i.e.,  long-term growth  of capital  and high  current income) by
investing in  equity securities  that  the Adviser  believes to  be  undervalued
relative  to  the stock  market in  general at  the time  of purchase.  It seeks
superior market  cycle  total  returns,  with an  emphasis  on  strong  relative
performance  in  falling  markets.  The Portfolio  invests  primarily  in equity
securities of  large capitalization  companies mainly  domiciled in  the  United
States.  With respect  to the  Portfolio, equity  securities include  common and
preferred stocks, convertible  securities, and rights  and warrants to  purchase
common  stocks. Under normal  circumstances, the Portfolio  will invest at least
65% of the value of its total assets in equity securities.
 
    The Adviser  invests with  the philosophy  that a  diversified portfolio  of
undervalued  equity securities will outperform the market over the long term, as
well  as  preserve  principal   in  difficult  market  environments.   Companies
considered  attractive will have  the following characteristics:  1) stocks most
often will have distinctly above average  dividend yields, 2) the market  prices
of  the stocks will be  undervalued relative to the  normal earning power of the
company, 3) many stocks will sell at close to or below the replacement value  of
their  assets and  4) most  stocks' market  prices will  have underperformed the
general market  due to  a lower  level of  investor expectations  regarding  the
company  outlook.  The thrust  of  this approach  is  to seek  investments where
current investor enthusiasm is low,  as reflected in their valuations.  Exposure
is  reduced when the investment community's  perceptions improve and the company
approaches fair valuation.
 
    The Adviser  takes  a long-term  investment  approach by  placing  a  strong
emphasis  on its  ability to  determine attractive  values and  does not  try to
determine short-term changes  in the  general market level.  The Portfolio  will
maintain  diversity among industries by not investing more than 25% of its total
assets in equity securities  of issuers in any  one industry. The Portfolio  may
invest  up  to 25%  of  its total  assets in  the  equity securities  of foreign
issuers, including  American  Depositary Receipts.  See  "Additional  Investment
Information."
 
    Any remaining assets of the Portfolio not invested as described above may be
invested  in  certain  securities or  obligations  as set  forth  in "Additional
Investment Information" below.
 
THE BALANCED PORTFOLIO
 
    The investment objective of the Balanced Portfolio is to achieve high  total
return  while preserving  capital by investing  in a  combination of undervalued
equity  securities   and   fixed   income  securities.   The   Portfolio   seeks
 
                                       13
<PAGE>
strong  total  returns in  all  market conditions,  with  a special  emphasis on
minimizing interim declines during falling equity markets. It primarily  invests
in  large capitalization equity securities, intermediate-maturity bonds and cash
equivalents.
 
    The Adviser  uses a  valuation-driven  balanced portfolio  philosophy  which
combines  separate  equity, fixed  income and  asset allocation  strategies. The
equity investment approach is the same one used for the Value Equity  Portfolio.
This produces a portfolio of stocks with low price-to-earnings and price-to-book
ratios  and high dividend  yields. The fixed income  strategy values bonds using
historical yield differentials. Short and intermediate government, corporate and
mortgage bonds are used  exclusively to implement  the Portfolio's fixed  income
strategy.  The asset  allocation strategy shifts  the stock/bond/cash equivalent
mix relative to  calculated risk  and return  levels. All  three strategies  use
historical capital market behavior to reach conclusions.
 
    The  Portfolio  will typically  maintain between  35% and  65% of  its total
assets invested in equity securities, depending upon the Adviser's assessment of
market conditions.  With respect  to the  Portfolio, equity  securities  include
common  and preferred stocks, convertible securities, and rights and warrants to
purchase common stocks. In overvalued equity markets, the common stock  exposure
will  be at the low end of this  range. It is expected that equity exposure will
average approximately 55% over time.
 
    Fixed income  securities in  which  the Portfolio  may invest  include  U.S.
Government   securities,  mortgage-backed  securities,   corporate  bonds,  bank
obligations and other short-term money market instruments. The average  maturity
of   the  fixed   income  securities  in   the  Portfolio   will,  under  normal
circumstances, be  approximately  five  years,  although  this  will  vary  with
changing  market conditions. Up  to 25% of  the Portfolio's total  assets may be
invested in  the  securities  of foreign  issuers.  See  "Additional  Investment
Information."
 
                       ADDITIONAL INVESTMENT INFORMATION
 
    DEPOSITARY  RECEIPTS.  Each  portfolio is permitted  to invest indirectly in
securities of  foreign  companies  through  sponsored  or  unsponsored  American
Depositary  Receipts  ("ADRs"), Global  Depositary  Receipts ("GDRs")  and other
types  of  Depositary  Receipts  (which,  together  with  ADRs  and  GDRs,   are
hereinafter  collectively referred to  as "Depositary Receipts"),  to the extent
such Depositary Receipts are  or become available.  Depositary Receipts are  not
necessarily  denominated in the  same currency as  the underlying securities. In
addition, the  issuers  of  the  securities  underlying  unsponsored  Depositary
Receipts  are not  obligated to disclose  material information in  the U.S. and,
therefore, there may be  less information available  regarding such issuers  and
there  may not be a correlation between such information and the market value of
the Depositary Receipts. ADRs are Depositary Receipts typically issued by a U.S.
financial institution which evidence ownership  interests in a security or  pool
of  securities issued by  a foreign issuer.  GDRs and other  types of Depositary
Receipts are typically issued by foreign banks or trust companies, although they
also may  be  issued by  U.S.  financial institutions,  and  evidence  ownership
interests  in a security or  pool of securities issued by  either a foreign or a
U.S. corporation. Generally, Depositary Receipts in registered form are designed
for use in the U.S. securities market and Depositary Receipts in bearer form are
designed for use  in securities markets  outside the U.S.  For purposes of  each
Portfolio's  investment  policies,  the  Portfolio's  investments  in Depositary
Receipts will be deemed to be investments in the underlying securities.
 
    FOREIGN INVESTMENT.   Each  Portfolio may  invest in  securities of  foreign
issuers. Investment in obligations of foreign issuers and in foreign branches of
domestic    banks   involves   somewhat    different   investment   risks   than
 
                                       14
<PAGE>
those affecting  obligations of  U.S.  issuers. There  may be  limited  publicly
available  information with respect to foreign  issuers, and foreign issuers are
not generally subject  to uniform accounting,  auditing and financial  standards
and  requirements comparable  to those applicable  to U.S.  companies. There may
also be  less  government  supervision  and  regulation  of  foreign  securities
exchanges, brokers and listed companies than in the U.S. Many foreign securities
markets  have substantially less volume than U.S. national securities exchanges,
and securities of some  foreign issuers are less  liquid and more volatile  than
securities  of  comparable  domestic issuers.  Brokerage  commissions  and other
transaction costs on foreign securities  exchanges are generally higher than  in
the  U.S.  Dividends and  interest paid  by  foreign issuers  may be  subject to
withholding and  other foreign  taxes,  which may  decrease  the net  return  on
foreign investments as compared to dividends and interest paid to the Portfolios
by  domestic companies. It is not expected  that a Portfolio or its shareholders
would be able to claim a credit for  U.S. tax purposes with respect to any  such
foreign  taxes.  See  "Taxes."  Additional risks  include  future  political and
economic developments, the possibility that a foreign jurisdiction might  impose
or   change  withholding  taxes  on  income  payable  with  respect  to  foreign
securities, possible seizure,  nationalization or expropriation  of the  foreign
issuer  or foreign  deposits and the  possible adoption  of foreign governmental
restrictions such as exchange controls.
 
    Such investments in securities of foreign issuers are frequently denominated
in foreign currencies, and since the Portfolios may temporarily hold  uninvested
reserves  in bank deposits in foreign  currencies, the value of each Portfolio's
assets as measured in U.S. dollars  may be affected favorably or unfavorably  by
changes  in  currency  rates  and  in  exchange  control  regulations,  and  the
Portfolios may  incur  costs  in connection  with  conversions  between  various
currencies.
 
    FORWARD  FOREIGN CURRENCY EXCHANGE CONTRACTS.  Each Portfolio may enter into
forward foreign currency exchange  contracts ("forward contracts") that  provide
for  the purchase  or sale  of an amount  of a  specified foreign  currency at a
future date. Purposes for  which such contracts may  be used include  protecting
against  a decline  in a  foreign currency against  the U.S.  dollar between the
trade date and settlement  date when the Portfolio  purchases or sells  non-U.S.
dollar  denominated securities,  locking in the  U.S. dollar  value of dividends
declared on securities held by the  Portfolio and generally protecting the  U.S.
dollar   value  of  securities  held  by   a  Portfolio  against  exchange  rate
fluctuation. Such contracts may also be used as a protective measure against the
effects  of  fluctuating  rates  of  currency  exchange  and  exchange   control
regulations.  While such forward contracts may limit  losses to a Portfolio as a
result of exchange  rate fluctuation, they  will also limit  any gains that  may
otherwise have been realized. See "Investment Objectives and Policies -- Forward
Foreign Currency Exchange Contracts" in the Statement of Additional Information.
 
    LOANS  OF PORTFOLIO SECURITIES.   Each Portfolio may  lend its securities to
brokers, dealers, domestic and foreign banks or other financial institutions for
the purpose of increasing its net investment income. These loans must be secured
continuously by cash or equivalent collateral, or by a letter of credit at least
equal to the  market value  of the securities  loaned plus  accrued interest  or
income.  There may be a risk of delay in recovery of the securities or even loss
of rights  in  the  collateral  should  the  borrower  of  the  securities  fail
financially.  Each Portfolio  will not  enter into  securities loan transactions
exceeding, in the  aggregate, 33  1/3% of the  market value  of the  Portfolio's
total  assets. Securities lending entails certain  risks of delay in recovery or
loss of rights in collateral in the event of the insolvency of the borrower. For
more detailed information  about securities lending  see "Investment  Objectives
and Policies" in the Statement of Additional Information.
 
                                       15
<PAGE>
    MONEY  MARKET INSTRUMENTS.   Each Portfolio is permitted  to invest in money
market  instruments,  although  the  Portfolios  intend  to  stay  invested   in
securities   satisfying  their  primary  investment   objective  to  the  extent
practical. Each  Portfolio  may  make money  market  investments  pending  other
investment  or settlement  for liquidity, or  in adverse  market conditions. The
money market investments  permitted for the  Portfolios include: obligations  of
the  United States Government and its agencies and instrumentalities; other debt
securities; commercial paper including bank obligations; certificates of deposit
(including Eurodollar certificates of  deposit); and repurchase agreements.  For
more detailed information about these money market investments, see "Description
of Securities and Ratings" in the Statement of Additional Information.
 
    REPURCHASE  AGREEMENTS.  Each Portfolio may enter into repurchase agreements
with brokers, dealers or  banks that meet the  credit guidelines established  by
the  Fund's Board of Directors. In a  repurchase agreement, the Portfolio buys a
security from a seller  that has agreed  to repurchase it  at a mutually  agreed
upon  date and price, reflecting the interest rate effective for the term of the
agreement. The term of these agreements  is usually from overnight to one  week,
and  never exceeds  one year.  Repurchase agreements  may be  viewed as  a fully
collateralized loan of  money by  the Portfolio  to the  seller. Each  Portfolio
always  receives securities with a  market value at least  equal to the purchase
price (including accrued interest) as  collateral, and this value is  maintained
during  the term  of the  agreement. If the  seller defaults  and the collateral
value declines, the Portfolio might incur a loss. If bankruptcy proceedings  are
commenced  with  respect to  the seller,  the  Portfolio's realization  upon the
collateral may  be  delayed or  limited.  The aggregate  of  certain  repurchase
agreements  and  certain  other  investments  is  limited  as  set  forth  under
"Investment Limitations."
 
    STOCK OPTIONS, FUTURES CONTRACTS AND OPTIONS ON FUTURES CONTRACTS.  In order
to remain fully invested,  and to reduce transaction  costs, each Portfolio  may
utilize  appropriate stock  futures contracts and  options to  a limited extent.
Because transaction costs associated with futures and options may be lower  than
the  costs of investing in stocks directly, it is expected that the use of index
futures and options to  facilitate cash flows may  reduce a Portfolio's  overall
transaction   costs.  The  Portfolios   will  engage  in   futures  and  options
transactions only for hedging purposes.
 
    Each Portfolio may enter into futures contracts provided that not more  than
5% of the Portfolio's total assets are required as deposit to secure obligations
under such contracts.
 
    The  primary risks associated  with the use  of futures and  options are (i)
imperfect correlation between the change in  market value of the stocks held  by
the  Portfolio and  the prices  of futures  and options  relating to  the stocks
purchased or sold by the Portfolio; and (ii) possible lack of a liquid secondary
market for a  futures contract and  the resulting inability  to close a  futures
position which could have an adverse impact on the Portfolio's ability to hedge.
In  the opinion of the  Board of Directors, the risk  that the Portfolio will be
unable to close out a futures position or options contract will be minimized  by
only  entering into futures contracts or options transactions traded on national
exchanges and for which there appears to be a liquid secondary market. For  more
detailed  information about futures transactions  see "Investment Objectives and
Policies" in the Statement of Additional Information.
 
    TEMPORARY INVESTMENTS.  During periods in which the Adviser believes changes
in economic, financial or political conditions make it advisable a Portfolio may
reduce its  holdings in  equity and  other securities,  for temporary  defensive
purposes,  and the Portfolio may invest  in certain short-term (less than twelve
months to maturity) and  medium-term (not greater than  five years to  maturity)
debt securities or may hold cash. The short-
 
                                       16
<PAGE>
term  and medium-term debt securities in which a Portfolio may invest consist of
(a) obligations of  the U.S.  or foreign country  governments, their  respective
agencies or instrumentalities; (b) bank deposits and bank obligations (including
certificates  of deposit,  time deposits  and bankers'  acceptances) of  U.S. or
foreign country banks denominated in any currency; (c) floating rate  securities
and  other  instruments  denominated  in any  currency  issued  by international
development agencies; (d)  finance company  and corporate  commercial paper  and
other  short-term  corporate  debt  obligations  of  U.S.  and  foreign  country
corporations  meeting  the  Portfolio's   credit  quality  standards;  and   (e)
repurchase  agreements  with  banks  and  broker-dealers  with  respect  to such
securities. For temporary  defensive purposes, the  Portfolios intend to  invest
only  in short-term and medium-term debt securities that the Adviser believes to
be of high quality, i.e., subject to relatively low risk of loss of interest  or
principal.
 
    WHEN-ISSUED  AND DELAYED DELIVERY  SECURITIES.  Each  Portfolio may purchase
securities on a  when-issued or  delayed delivery basis.  In such  transactions,
instruments  are bought with payment and delivery  taking place in the future in
order to secure what is considered to  be an advantageous yield or price at  the
time  of the transaction. Delivery of and  payment for these securities may take
as long as a month or more after  the date of the purchase commitment, but  will
take  place no  more than  120 days  after the  trade date.  Each Portfolio will
maintain with the Custodian  a separate account with  a segregated portfolio  of
high-grade  debt  securities  or cash  in  an  amount at  least  equal  to these
commitments. The payment obligation and the interest rates that will be received
are each  fixed at  the  time a  Portfolio enters  into  the commitment  and  no
interest  accrues to the  Portfolio until settlement. Thus,  it is possible that
the market value at  the time of  settlement could be higher  or lower than  the
purchase  price if  the general  level of  interest rates  has changed.  It is a
current policy of each Portfolio not  to enter into when-issued commitments  and
delayed  delivery commitments  exceeding, in  the aggregate,  15% of  the market
value  of  the  Portfolio's  total  assets  less  liabilities  other  than   the
obligations created by these commitments.
 
                             INVESTMENT LIMITATIONS
 
    As  a  diversified  investment company,  each  Portfolio is  subject  to the
following limitations: (a) as to  75% of its total  assets, a Portfolio may  not
invest  more than 5%  of its total assets  in the securities  of any one issuer,
except obligations  of  the  United  States  Government  and  its  agencies  and
instrumentalities,  and  (b)  a Portfolio  may  not  own more  than  10%  of the
outstanding voting securities of any one issuer.
 
   
    Each Portfolio also operates under certain investment restrictions that  are
deemed  fundamental limitations and may be changed only with the approval of the
holders of a majority  of such Portfolio's  outstanding shares. See  "Investment
Limitations"  in  the Statement  of  Additional Information.  In  addition, each
Portfolio operates  under  certain  non-fundamental  investment  limitations  as
described  below and in the Statement  of Additional Information. Each Portfolio
may not  (i) enter  into repurchase  agreements  with more  than seven  days  to
maturity  if, as a result, more than 10%  of the market value of the Portfolio's
net assets would be invested in such repurchase agreements and other investments
for which market  quotations are not  readily available or  which are  otherwise
illiquid;  (ii) borrow money,  except from banks  for extraordinary or emergency
purposes, and then only  in amounts up  to 10% of the  value of the  Portfolio's
total  assets, taken at  cost at the  time of borrowing,  or purchase securities
while borrowings  exceed 5%  of  its total  assets;  (iii) mortgage,  pledge  or
hypothecate  any assets except in connection  with any such borrowing in amounts
up to 10% of the value of the Portfolio's net
    
 
                                       17
<PAGE>
assets at the  time of  borrowing; (iv)  invest in  fixed time  deposits with  a
duration  of over seven calendar days; or (v) invest in fixed time deposits with
a duration of from two business days to seven calendar days if more than 10%  of
the Portfolio's total assets would be invested in these deposits.
 
                             MANAGEMENT OF THE FUND
 
   
    INVESTMENT  ADVISER.  Morgan Stanley Asset Management Inc. is the Investment
Adviser and Administrator of the Fund  and each Portfolio. The Adviser  provides
investment  advice and portfolio management  services, pursuant to an Investment
Advisory Agreement  and, subject  to  the supervision  of  the Fund's  Board  of
Directors,  makes each Portfolio's day-to-day investment decisions, arranges for
the execution of portfolio transactions  and generally manages each  Portfolio's
investments.  The Adviser is  entitled to receive from  each Portfolio an annual
management fee, payable quarterly, equal to the percentage of average daily  net
assets  set  forth in  the table  below. However,  the Adviser  has agreed  to a
reduction in  the  fees  payable to  it  and  to reimburse  the  Portfolios,  if
necessary,  if such fees would cause the  total annual operating expenses of any
Portfolio to exceed the  respective percentage of average  daily net assets  set
forth in the table below.
    
 
<TABLE>
<CAPTION>
                                                       MAXIMUM TOTAL OPERATING
                                                               EXPENSES
                                                          AFTER FEE WAIVERS
                                       MANAGEMENT    ----------------------------
             PORTFOLIO                     FEE          CLASS A        CLASS B
- ------------------------------------  -------------  -------------  -------------
<S>                                   <C>            <C>            <C>
Small Cap Value Equity Portfolio            0.85%          1.00%          1.25%
Value Equity Portfolio                      0.50%          0.70%          0.95%
Balanced Portfolio                          0.50%          0.70%          0.95%
</TABLE>
 
   
    The  Adviser, with  principal offices  at 1221  Avenue of  the Americas, New
York, New  York  10020,  conducts a  worldwide  portfolio  management  business,
providing  a broad  range of portfolio  management services to  customers in the
United States and abroad. At December  31, 1995, the Adviser, together with  its
affiliated    asset   management   companies,   managed   investments   totaling
approximately $57.4 billion, including approximately $41.9 billion under  active
management  and  $15.5  billion as  Named  Fiduciary or  Fiduciary  Adviser. See
"Management of the Fund" in the Statement of Additional Information.
    
 
PORTFOLIO MANAGERS
 
   
    Stephen C. Sexauer and Alford E.  Zick, Jr. have primary responsibility  for
managing  the Balanced Portfolio and the Value Equity Portfolio; Mr. Sexauer and
Mr. Zick  have  had  such  responsibility since  the  Portfolios'  inception  in
February  and  January,  1990,  respectively. Christian  K.  Stadlinger  has had
primary responsibility for managing the Small Cap Value Equity Portfolio and has
had such responsibility since its inception in December, 1992.
    
 
    STEPHEN C. SEXAUER.  Mr. Sexauer is  a Principal of Morgan Stanley and is  a
member  of the investment management team  of the Adviser's Chicago affiliate as
well as Vice President of the Adviser. In addition to portfolio management,  his
equity  research responsibilities include aerospace, industrials, capital goods,
transportation, and diversified financial companies. Mr. Sexauer joined the firm
in July  1989  after  three years  as  a  Vice President  at  Salomon  Brothers.
Previously,  he was with  Merrill Lynch Economics  and Wharton Econometrics. Mr.
Sexauer received a  B.S. in  Economics from the  University of  Illinois and  an
M.B.A. in Economics and Statistics from the University of Chicago.
 
                                       18
<PAGE>
    CHRISTIAN  K. STADLINGER.  Mr. Stadlinger is a Vice President of the Adviser
and manages  the  small-cap  value  equity  product  of  the  Adviser's  Chicago
affiliate. He became a member of the Adviser's Chicago large cap value portfolio
management  team, specializing  in quantitative  and fundamental  research, upon
completion of  his doctoral  dissertation at  Northwestern University  in  April
1989.  Mr.  Stadlinger was  the  catalyst in  the  development of  the Adviser's
small-cap value product,  and he  continues to research  and develop  structured
valuation  techniques in the area  of small cap investing.  Mr. Stadlinger has a
degree in Computer Science and Economics from the University of Vienna, a  Ph.D.
in Economics from Northwestern University, and is a Certified Financial Analyst.
 
    ALFORD  E. ZICK, JR.   Mr. Zick  is a Principal  of Morgan Stanley  and is a
member of the investment management team of the Adviser's Chicago affiliate.  In
addition  to portfolio management, his  equity research responsibilities include
consumer staples, retail  and insurance  companies. He  became a  member of  the
Adviser's  Chicago investment management team in August 1989, after an extensive
career in asset management with Chicago Pacific Corporation, Staley Continental,
Inc., and A.E. STALEY Manufacturing Company. Mr. Zick has a degree in accounting
from the University of Illinois.
 
    ADMINISTRATOR.   The  Adviser also  provides  the Fund  with  administrative
services  pursuant to an  Administration Agreement. The  services provided under
the Administration Agreement are subject to the supervision of the Officers  and
the  Board of  Directors of  the Fund  and include  day-to-day administration of
matters related  to the  corporate existence  of the  Fund, maintenance  of  its
records, preparation of reports, supervision of the Fund's arrangements with its
custodian,  and  assistance  in  the  preparation  of  the  Fund's  registration
statements under  federal  and state  laws.  The Administration  Agreement  also
provides  that  the Administrator,  through its  agents,  will provide  the Fund
dividend disbursing  and transfer  agent services.  For its  services under  the
Administration  Agreement, the Fund pays the Adviser  a monthly fee which, on an
annual basis equals, 0.15% of the average daily net assets of each Portfolio.
 
   
    Under an agreement between  the Adviser and The  Chase Manhattan Bank,  N.A.
("Chase"),  Chase provides  certain administrative  services to  the Fund.  In a
merger completed on September 1, 1995, Chase succeeded to all of the rights  and
obligations  under the U.S.  Trust Administration Agreement  between the Adviser
and the United  States Trust  Company of New  York ("U.S.  Trust"), pursuant  to
which  U.S. Trust had  agreed to provide certain  administrative services to the
Fund.  Pursuant  to  a  delegation  clause  in  the  U.S.  Trust  Administration
Agreement,  U.S. Trust  delegated its  administration responsibilities  to Chase
Global Funds Services Company ("CGFSC"), formerly known as Mutual Funds  Service
Company  which after  the merger with  Chase is  a subsidiary of  Chase and will
continue to provide  certain administrative  services to the  Fund. The  Adviser
supervises  and  monitors such  administrative services  provided by  CGFSC. The
services  provided  under  the  Administration  Agreement  and  the  U.S.  Trust
Administration  Agreement are  also subject to  the supervision of  the Board of
Directors of the  Fund. The  Board of  Directors of  the Fund  has approved  the
provision  of services described above  pursuant to the Administration Agreement
and the U.S. Trust  Administration Agreement as being  in the best interests  of
the  Fund. CGFSC's business address is  73 Tremont Street, Boston, Massachusetts
02108-3913. For additional information regarding the Administration Agreement or
the U.S. Trust  Administration Agreement, see  "Management of the  Fund" in  the
Statement of Additional Information.
    
 
    DIRECTORS  AND OFFICERS.  Pursuant to  the Fund's Articles of Incorporation,
the Board of Directors  decides upon matters of  general policy and reviews  the
actions  of the Fund's  Adviser, Administrator and  Distributor. The Officers of
the Fund conduct and supervise its daily business operations.
 
                                       19
<PAGE>
   
    DISTRIBUTOR.   Morgan Stanley  serves as  the exclusive  Distributor of  the
shares  of  the Fund.  Under its  Distribution Agreement  with the  Fund, Morgan
Stanley sells  shares  of each  Portfolio  upon the  terms  and at  the  current
offering  price described in this Prospectus. Morgan Stanley is not obligated to
sell any certain number of shares of any Portfolio.
    
 
   
    Each Portfolio currently offers only the  classes of shares offered by  this
Prospectus. Each Portfolio may in the future offer one or more classes of shares
with  features, distribution expenses or other  expenses that are different from
those of the classes currently offered.
    
 
   
    The Fund has  adopted a Plan  of Distribution  with respect to  the Class  B
shares  of each  Portfolio pursuant to  Rule 12b-1  under the 1940  Act (each, a
"Plan"). Under  each Plan,  the Distributor  is entitled  to receive  from  each
Portfolio  a distribution  fee, which  is accrued  daily and  paid quarterly, of
0.25% of the average daily net assets of the Class B shares of each Portfolio on
an annualized basis. The  Distributor expects to reallocate  most of its fee  to
its   investment  representatives.  The  Distributor  may,  in  its  discretion,
voluntarily waive from time to time all  or any portion of its distribution  fee
and  each of the Distributor and the Adviser is free to make additional payments
out of its own  assets to promote  the sale of  Fund shares, including  payments
that  compensate financial institutions for distribution services or shareholder
services.
    
 
   
    Each Plan is designed to compensate the Distributor for its services, not to
reimburse the Distributor for its expenses,  and the Distributor may retain  any
portion  of the fee that it does not expend in fulfillment of its obligations to
the Fund.
    
 
    EXPENSES.  Each Portfolio is responsible  for payment of certain other  fees
and  expenses  (including  legal  fees, accountants'  fees,  custodial  fees and
printing and mailing  costs) specified  in the  Administration and  Distribution
Agreements.
 
                                       20
<PAGE>
   
                               PURCHASE OF SHARES
    
 
   
    Class A and Class B shares of each Portfolio may be purchased, without sales
commission,  at the net asset  value per share next  determined after receipt of
the purchase order by the Portfolios. See "Valuation of Shares."
    
 
   
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
    
 
   
    For a Portfolio opened on  or after January 2,  1996 (a "New Account"),  the
minimum  initial investment  and minimum account  size are $500,000  for Class A
shares and $100,000 minimum  for Class B shares.  Managed Accounts may  purchase
Class  A shares without being subject to a minimum initial investment or minimum
account size requirements for a Portfolio  account. Officers of the Adviser  and
its  affiliates are subject to the minimums for a Portfolio account, except they
may purchase Class B shares subject to a minimum initial investment and  minimum
account size of $5,000 for a Portfolio account.
    
 
   
    If the value of a New Account containing Class A shares falls below $500,000
(but  remains at  or above $100,000)  because of  shareholder redemption(s), the
Fund will  notify  the shareholder,  and  if  the account  value  remains  below
$500,000  (but remains at or above $100,000) for a continuous 60-day period, the
Class A  shares in  such account  will convert  to Class  B shares  and will  be
subject  to the distribution  fee and other  features applicable to  the Class B
shares. The Fund, however,  will not convert  Class A shares  to Class B  shares
based  solely upon  changes in  the market  that reduce  the net  asset value of
shares. Under  current tax  law, conversions  between share  classes are  not  a
taxable event to the shareholder.
    
 
   
    Shares  in a Portfolio account opened prior  to January 2, 1996 (a "Pre-1996
Account") were  designated  Class A  shares  on January  2,  1996. Shares  in  a
Pre-1996  Account  with  a  value  of  $100,000 or  more  on  March  1,  1996 (a
"Grandfathered Class A Account") remained  Class A shares regardless of  account
size  thereafter. Except for shares  in a Managed Account,  shares in a Pre-1996
Account with a value of  less than $100,000 on  March 1, 1996 (a  "Grandfathered
Class  B Account") converted to  Class B shares on  March 1, 1996. Grandfathered
Class A Accounts and Managed Accounts are not subject to conversion from Class A
shares to Class B shares.
    
 
   
    Investors may also invest in the  Fund by purchasing shares through a  trust
department, broker, dealer, agent, financial planner, financial services firm or
investment  adviser.  An  investor  may  be  charged  an  additional  service or
transaction fee by that institution. The minimum investment levels may be waived
at the discretion  of the  Adviser for (i)  certain employees  and customers  of
Morgan  Stanley  or  its  affiliates  and  certain  trust  departments, brokers,
dealers, agents,  financial planners,  financial services  firms, or  investment
advisers  that  have  entered  into  an agreement  with  Morgan  Stanley  or its
affiliates; and (ii) retirement and deferred compensation plans and trusts  used
to  fund such  plans, including,  but not limited  to, those  defined in Section
401(a), 403(b) or  457 of the  Internal Revenue  Code of 1986,  as amended,  and
"rabbi  trusts".  The  Fund  reserves  the  right  to  modify  or  terminate the
conversion features of  the shares  as stated above  at any  time upon  60-days'
notice to shareholders.
    
 
   
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
    
 
    If  the value of a  New Account falls below  $100,000 because of shareholder
redemption(s), the Fund will  notify the shareholder, and  if the account  value
remains  below  $100,000 for  a  continuous 60-day  period,  the shares  in such
account are subject to redemption  by the Fund and,  if redeemed, the net  asset
value  of  such shares  will  be promptly  paid  to the  shareholder.  The Fund,
however, will not  redeem shares based  solely upon changes  in the market  that
reduce the net asset value of shares.
 
                                       21
<PAGE>
   
    For  purposes of redemptions by the Fund, the foregoing minimum account size
requirements do not  apply to  New Accounts containing  Class B  shares held  by
officers of the Adviser or its affiliates. However, if the value of such account
held  by an officer of the Adviser  or its affiliates falls below $5,000 because
of shareholder redemption(s), the Fund will  notify the shareholder, and if  the
account  value remains $5,000 for a continuous 60-day period, the shares in such
account are subject to redemption  by the Fund and,  if redeemed, the net  asset
value of such shares will be promptly paid to the shareholder.
    
 
   
    Grandfathered  Class A Accounts, Grandfathered  Class B Accounts and Managed
Accounts are not subject to involuntary redemption.
    
 
   
    The  Fund  reserves  the  right  to  modify  or  terminate  the  involuntary
redemption  features of  the shares  as stated above  at any  time upon 60-days'
notice to shareholders.
    
 
   
CONVERSION FROM CLASS B TO CLASS A SHARES
    
 
   
    If the value of Class B shares in a Portfolio account increases, whether due
to shareholder share  purchases or  market activity,  to $500,000  or more,  the
Class  B shares  will convert  to Class  A shares.  Under current  tax law, such
conversion is not a taxable event  to the shareholder. Class A shares  converted
from  Class B shares are  subject to the same  minimum account size requirements
that are applicable to New Accounts containing Class A shares, as stated  above.
The  Fund reserves the right  to modify or terminate  this conversion feature at
any time upon 60-days' notice to shareholders.
    
 
   
INITIAL PURCHASES DIRECTLY FROM THE FUND
    
 
   
    The Fund's determination of an investor's eligibility to purchase shares  of
a  given class will  take precedence over  the investor's selection  of a class.
Assuming the investor is eligible for the  class, the Fund will select the  most
favorable class for the investor, if the investor has not done so.
    
 
   
1) BY  CHECK.   An account may  be opened  by completing and  signing an Account
   Registration Form and mailing it, together with a check ($500,000 minimum for
   Class A shares  of each Portfolio  and $100,000  for Class B  shares of  each
   Portfolio,  with certain exceptions  for Morgan Stanley  employees and select
   customers) payable to "Morgan Stanley Institutional Fund, Inc. --  [portfolio
   name]," to:
    
 
   
      Morgan Stanley Institutional Fund, Inc.
      P.O. Box 2798
      Boston, Massachusetts 02208-2798
    
 
   
     Payment will  be accepted only  in U.S. dollars,  unless prior approval for
  payment by  other currencies  is given  by the  Fund. The  Portfolio(s) to  be
  purchased should be designated on the Account Registration Form. For purchases
  by  check,  the Fund  is  ordinarily credited  with  Federal Funds  within one
  business day. Thus, your purchase of shares by check is ordinarily credited to
  your account  at the  net asset  value  per share  of the  relevant  Portfolio
  determined on the next business day after receipt.
    
 
                                       22
<PAGE>
   
2) BY  FEDERAL  FUNDS WIRE.   Purchases  may be  made by  having your  bank wire
   Federal Funds to the Fund's bank  account. In order to ensure prompt  receipt
   of your Federal Funds Wire, it is important that you follow these steps:
    
 
   
A.   Telephone  the Fund  (toll free: 1-800-548-7786)  and provide  us with your
    name, address,  telephone  number,  Social Security  or  Tax  Identification
    Number,  the  portfolio(s) selected,  the class  selected, the  amount being
    wired, and by  which bank.  We will  then provide  you with  a Fund  account
    number.  (Investors with existing accounts should also notify the Fund prior
    to wiring funds.)
    
 
   
B.   Instruct  your  bank to  wire  the  specified amount  to  the  Fund's  Wire
    Concentration  Bank Account (be sure  to have your bank  include the name of
    the portfolio(s)  selected,  the  class  selected  and  the  account  number
    assigned to you) as follows:
    
 
   
    Chase Manhattan Bank, N.A.
    One Manhattan Plaza
    New York, NY 10081-1000
    ABA #021000021
    DDA #910-2-733293
    Attn: Morgan Stanley Institutional Fund, Inc.
    Ref: (Portfolio name, your account number, your account name)
    
 
   
    Please call the Fund at 1-800-548-7786 prior to wiring funds.
    
 
   
C.   Complete and sign the Account Registration  Form and mail it to the address
    shown thereon.
    
 
   
  Purchase orders for shares of the  Portfolios which are received prior to  the
  regular  close of the NYSE (currently 4:00 p.m. Eastern Time) will be executed
  at the price computed  on the date  of receipt as long  as the Transfer  Agent
  receives  payment by check or  in Federal Funds prior  to the regular close of
  the NYSE on such day.
    
 
   
  Federal Funds purchase orders will be accepted only on a day on which the Fund
  and Chase (the "Custodian Bank") are open for business. Your bank may charge a
  service fee for wiring Federal Funds.
    
 
   
3) BY BANK WIRE.   The  same procedure outlined  under "By  Federal Funds  Wire"
   above  must be  followed in  purchasing shares  by bank  wire. However, money
   transferred by bank wire may or may  not be converted into Federal Funds  the
   same  day, depending on the time the  money is received and the bank handling
   the wire. Prior to such conversion, an investor's money will not be invested.
   Your bank may charge a service fee for wiring funds.
    
 
   
ADDITIONAL INVESTMENTS
    
 
    You may  add to  your account  at any  time (minimum  additional  investment
$1,000  for each Portfolio,  except for automatic  reinvestment of dividends and
capital gains  distributions for  which  there are  no minimums)  by  purchasing
shares  at net asset  value by mailing a  check to the  Fund (payable to "Morgan
Stanley Institutional Fund, Inc. -- [portfolio  name]") at the above address  or
by  wiring monies to the Custodian Bank  as outlined above. It is very important
that your account name,  portfolio name and the  class selected be specified  in
the  letter or wire to assure proper crediting to your account. In order to help
to ensure that your wire orders are
 
                                       23
<PAGE>
   
invested promptly, you are requested to notify one of the Fund's representatives
(toll free 1-800-548-7786)  prior to  sending the  wire. Additional  investments
will  be  applied to  purchase additional  shares in  the same  class held  by a
shareholder in a Portfolio account.
    
 
OTHER PURCHASE INFORMATION
 
    The purchase price of the  Class A and Class B  shares of each portfolio  is
the  net asset value next determined after the order is received. See "Valuation
of Shares." An order received prior to the close of the New York Stock  Exchange
("NYSE"),  which is currently  4:00 p.m. Eastern  Time, will be  executed at the
price computed on the date of receipt; an order received after the close of  the
NYSE  will be executed at the price computed on the next day the NYSE is open as
long as the Transfer Agent receives payment  by check or in Federal Funds  prior
to the regular close of the NYSE on such day.
 
    Although  the legal rights of Class A  and Class B shares will be identical,
the different expenses borne  by each class will  result in different net  asset
values  and dividends. The net  asset value of Class  B shares will generally be
lower than the net asset value of Class A shares as a result of the distribution
expense charged to Class B shares. It  is expected, however, that the net  asset
value  per share of the two classes  will tend to converge immediately after the
recording of dividends  which will  differ by  approximately the  amount of  the
distribution expense accrual differential between the classes.
 
    In  the interest  of economy and  convenience, and because  of the operating
procedures of the Fund, certificates representing shares of the Portfolios  will
not  be issued. All shares  purchased are confirmed to  you and credited to your
account on the Fund's books  maintained by the Adviser  or its agents. You  will
have  the  same  rights  and  ownership  with  respect  to  such  shares  as  if
certificates had been issued.
 
    To ensure that checks are collected by the Fund, withdrawals of  investments
made  by check are  not presently permitted  until payment for  the purchase has
been received,  which may  take up  to eight  business days  after the  date  of
purchase.  As a condition  of this offering,  if a purchase  is cancelled due to
nonpayment or because your check does not clear, you will be responsible for any
loss the Fund or its  agents incur. If you are  already a shareholder, the  Fund
may  redeem shares from your account(s) to  reimburse the Fund or its agents for
any loss. In addition,  you may be prohibited  or restricted from making  future
investments in the Fund.
 
   
    Investors  may  also invest  in the  Fund by  purchasing shares  through the
Distributor.  See  "Purchase   of  Shares"  in   the  Statement  of   Additional
Information.
    
 
   
EXCESSIVE TRADING
    
 
   
    Frequent   trades  involving  either  substantial   portfolio  assets  or  a
substantial portion of your  account or accounts controlled  by you can  disrupt
management  of a portfolio and raise its expenses. Consequently, in the interest
of all the stockholders of each Portfolio and each Portfolio's performance,  the
Fund  may in its discretion bar a  stockholder that engages in excessive trading
of shares of any class  of a portfolio from further  purchases of shares of  the
Fund  for an indefinite period. The Fund  considers excessive trading to be more
than one purchase and sale involving shares of the same class of a portfolio  of
the  Fund  within  any  120-day  period. As  an  example,  exchanging  shares of
portfolios of the Fund as follows amounts to excessive trading: exchanging Class
A shares of Portfolio A for Class A shares of Portfolio B, then exchanging Class
A shares of Portfolio B for Class  A shares of Portfolio C and again  exchanging
Class A shares of Portfolio C for Class A shares of Portfolio B within a 120-day
    
 
                                       24
<PAGE>
   
period.  Two  types  of transactions  are  exempt from  these  excessive trading
restrictions: (1) trades  exclusively between money  market portfolios; and  (2)
trades  done  in  connection  with  an asset  allocation  service,  such  as TFM
Accounts, managed or advised by MSAM and/or any of its affiliates.
    
 
   
                              REDEMPTION OF SHARES
    
 
   
    You may  withdraw all  or  any portion  of the  amount  in your  account  by
redeeming  shares at any time. Please note  that purchases made by check are not
permitted to be redeemed until payment of the purchase has been collected, which
may take up to eight business days after purchase. The Fund will redeem Class  A
shares  or Class  B shares of  each Portfolio  at the next  determined net asset
value of shares to their  applicable class. On days that  both the NYSE and  the
Custodian  Bank are open for business, the net asset values per share of each of
the Portfolios is determined at the close of trading of the NYSE (currently 4:00
p.m. Eastern  Time).  Shares  of each  Portfolio  may  be redeemed  by  mail  or
telephone. No charge is made for redemption. Any redemption proceeds may be more
or  less  than the  purchase  price of  your  shares depending  on,  among other
factors, the market value of the investment securities held by the Portfolio.
    
 
   
BY MAIL
    
 
   
    Each Portfolio will redeem its Class A  shares or Class B shares at the  net
asset  value determined on the  date the request is  received, if the request is
received in "good  order" before  the regular close  of the  NYSE. Your  request
should  be addressed to Morgan Stanley  Institutional Fund, Inc., P.O. Box 2798,
Boston, Massachusetts 02208-2798,  except that deliveries  by overnight  courier
should be addressed to Morgan Stanley Institutional Fund, Inc., c/o Chase Global
Funds Services Company, 73 Tremont Street, Boston, Massachusetts 02108-3913.
    
 
   
    "Good  order"  means that  the  request to  redeem  shares must  include the
following documentation:
    
 
   
        (a)  A letter of instruction or a stock assignment specifying the  class
    and  number  of  shares or  dollar  amount  to be  redeemed,  signed  by all
    registered owners  of  the shares  in  the exact  names  in which  they  are
    registered;
    
 
   
        (b)   Any  required   signature  guarantees   (see  "Further  Redemption
    Information" below); and
    
 
   
        (c)   Other supporting  legal documents,  if required,  in the  case  of
    estates,  trusts, guardianships,  custodianships, corporations,  pension and
    profit-sharing plans and other organizations.
    
 
   
    Shareholders who are uncertain of requirements for redemption should consult
with a Morgan Stanley Institutional Fund representative.
    
 
BY TELEPHONE
 
    Provided you have previously elected the Telephone Redemption Option on  the
Account  Registration  Form, you  can  request a  redemption  of your  shares by
calling the Fund  and requesting  the redemption proceeds  be mailed  to you  or
wired  to your  bank. Please contact  one of Morgan  Stanley Institutional Fund,
Inc.'s  representatives  for  further  details.  In  times  of  drastic   market
conditions,  the telephone redemption  option may be  difficult to implement. If
you experience difficulty in making a telephone redemption, your request may  be
made  by mail  or overnight courier,  and will  be implemented at  the net asset
value next determined after it is received. Redemption requests sent to the Fund
through overnight courier  must be  sent to Morgan  Stanley Institutional  Fund,
Inc.,  c/o  Chase  Global Funds  Services  Company, 73  Tremont  Street, Boston,
Massachusetts
 
                                       25
<PAGE>
   
02108-3913. The Fund and the Fund's  transfer agent (the "Transfer Agent")  will
employ  reasonable  procedures  to  confirm  that  instructions  communicated by
telephone are  genuine.  These  procedures include  requiring  the  investor  to
provide  certain personal identification  information at the  time an account is
opened and  prior  to effecting  each  transaction requested  by  telephone.  In
addition,  all telephone transaction requests will be recorded and investors may
be required  to provide  additional  telecopied written  instructions  regarding
transaction   requests.  Neither  the  Fund  nor  the  Transfer  Agent  will  be
responsible for any loss, liability, cost or expense for following  instructions
received by telephone that either of them reasonably believes to be genuine.
    
 
    To  change the name of the commercial  bank or account designated to receive
redemption proceeds, a written request must be  sent to the Fund at the  address
above. Requests to change the bank or account must be signed by each shareholder
and each signature must be guaranteed.
 
FURTHER REDEMPTION INFORMATION
 
    Normally  the  Fund will  make payment  for all  shares redeemed  under this
procedure within one business  day of receipt  of the request,  but in no  event
will  payment be made more than seven days after receipt of a redemption request
in good  order.  However, payments  to  investors redeeming  shares  which  were
purchased  by check  will not be  made until  payment for the  purchase has been
collected, which may take up to eight days after the date of purchase. The  Fund
may  suspend the right of redemption or postpone the date upon which redemptions
are effected  at  times  when  the  NYSE  is  closed,  or  under  any  emergency
circumstances  as  determined by  the  Securities and  Exchange  Commission (the
"Commission").
 
    If the Board  of Directors determines  that it would  be detrimental to  the
best  interests of  the remaining  shareholders of  a Portfolio  to make payment
wholly or partly in cash, the Fund  may pay the redemption proceeds in whole  or
in  part by a distribution in-kind of securities  held by a Portfolio in lieu of
cash   in    conformity   with    applicable    rules   of    the    Commission.
Distributions-in-kind  will be made in  readily marketable securities. Investors
may incur brokerage charges on the  sale of portfolio securities so received  in
payment of redemptions.
 
    To  protect  your account,  the Fund  and its  agents from  fraud, signature
guarantees are required for  certain redemptions to verify  the identity of  the
person  who has  authorized a redemption  from your account.  Please contact the
Fund for further  information. See "Redemption  of Shares" in  the Statement  of
Additional Information.
 
                              SHAREHOLDER SERVICES
 
EXCHANGE FEATURES
 
   
    You  may exchange shares  that you own  in each Portfolio  for shares of any
other available  portfolio of  the  Fund (other  than the  International  Equity
Portfolio,  which is  closed to  new investors). In  exchanging for  shares of a
portfolio with more  than one  class, the  class of  shares you  receive in  the
exchange  will be determined in the same  manner as any other purchase of shares
and will not  be based  on the  class of  shares surrendered  for the  exchange.
Consequently,  the same minimum initial investment  and minimum account size for
determining the  class  of shares  received  in  the exchange  will  apply.  See
"Purchase  of Shares."  Shares of  the portfolios  may be  exchanged by  mail or
telephone. The privilege to exchange shares  by telephone is automatic and  made
available  without shareholder election. Before you make an exchange, you should
read the prospectus of the portfolio(s) in which you seek to invest. Because  an
exchange  transaction  is treated  as a  redemption followed  by a  purchase, an
    
 
                                       26
<PAGE>
   
exchange would be considered  a taxable event for  shareholders subject to  tax.
The  exchange privilege  is only available  with respect to  portfolios that are
registered for  sale  in  a  shareholder's  state  of  residence.  The  exchange
privilege  may be modified or  terminated by the Fund  at any time upon 60-days'
notice to shareholders.
    
 
   
BY MAIL
    
 
   
    In order to  exchange shares  by mail, you  should include  in the  exchange
request  the name, class of shares and account number of your current Portfolio,
the names of the portfolio(s) and class(es)  of shares into which you intend  to
exchange  shares, and the signatures of all registered account holders. Send the
exchange request  to Morgan  Stanley Institutional  Fund, Inc.,  P.O. Box  2798,
Boston, Massachusetts 02208-2798.
    
 
   
BY TELEPHONE
    
 
   
    When  exchanging shares by  telephone, have ready the  name, class of shares
and account number of the current Portfolio, the name(s) of the portfolio(s) and
class(es) of  shares into  which  you intend  to  exchange shares,  your  Social
Security  number  or Tax  I.D. number,  and your  account address.  Requests for
telephone exchanges received prior to 4:00 p.m. (Eastern Time) are processed  at
the close of business that same day based on the net asset value of the class of
the  portfolios involved  in the  exchange of shares  at the  close of business.
Requests received after 4:00 p.m. are  processed the next business day based  on
the  net  asset value  determined  at the  close of  business  on such  day. For
additional  information  regarding  responsibility   for  the  authenticity   of
telephoned instructions, see "Redemption of Shares -- By Telephone" above.
    
 
   
TRANSFER OF REGISTRATION
    
 
   
    You  may transfer  the registration  of any of  your Fund  shares to another
person by writing  to Morgan Stanley  Institutional Fund, Inc.,  P.O. Box  2798,
Boston,  Massachusetts 02208-2798.  As in the  case of  redemptions, the written
request must  be  received  in good  order  before  any transfer  can  be  made.
Transferring  the  registration of  shares may  affect  the eligibility  of your
account for a given class of a Portfolio's shares and may result in  involuntary
conversion or redemption of your shares. See "Purchase of Shares" above.
    
 
   
                              VALUATION OF SHARES
    
 
   
    The net asset value per share of a class of shares of each of the Portfolios
is  determined by dividing the total market value of the Portfolio's investments
and other assets attributable to such a class, less any liabilities attributable
to such a class, by the total number of outstanding shares of such class of  the
Portfolio.  Net  asset value  is  calculated separately  for  each class  of the
Portfolio. Net asset value per  share is determined as  of the regular close  of
the  NYSE on each day  that the NYSE is open  for business. Price information on
listed securities is  taken from the  exchange where the  security is  primarily
traded.  Securities  listed  on  a U.S.  securities  exchange  for  which market
quotations are available are valued at the last quoted sale price on the day the
valuation is made. Securities listed on  a foreign exchange are valued at  their
closing  price.  Unlisted securities  and listed  securities  not traded  on the
valuation date for which market quotations are not readily available are  valued
at  a price that is  considered to best represent fair  value within a range not
exceeding the  current asked  price nor  less than  the current  bid price.  The
current  bid and asked prices  are determined based on  the bid and asked prices
quoted on such valuation date by reputable brokers.
    
 
    Bonds and other fixed income securities are valued according to the broadest
and most representative  market, which will  ordinarily be the  over-the-counter
market.  Net asset value includes interest  on fixed income securities, which is
accrued daily.  In addition,  bonds and  other fixed  income securities  may  be
valued on the
 
                                       27
<PAGE>
basis  of prices provided by a pricing  service when such prices are believed to
reflect the  fair market  value of  such securities.  The prices  provided by  a
pricing  service are determined without  regard to bid or  last sale prices, but
take into account institutional size trading in similar groups of securities and
any developments related to  the specific securities.  Securities not priced  in
this  manner  are  valued  at  the most  recently  quoted  bid  price,  or, when
securities exchange valuations are used, at the latest quoted sale price on  the
day of valuation. If there is no such reported sale, the latest quoted bid price
will  be used. Securities purchased with remaining maturities of 60 days or less
are valued at amortized cost, if it approximates market value. In the event that
amortized cost does not  approximate market value,  market prices as  determined
above will be used.
 
   
    The value of other assets and securities for which no quotations are readily
available  (including restricted securities and unlisted foreign securities) and
those securities  the prices  for  which it  is  inappropriate to  determine  in
accordance with the above-stated procedures are determined in good faith at fair
value  using  methods determined  by  the Board  of  Directors. For  purposes of
calculating net  asset value  per share,  all assets  and liabilities  initially
expressed in foreign currencies will be translated into U.S. dollars at the mean
of the bid price and asked price of such currencies against the U.S. dollar last
quoted by any major bank.
    
 
   
    Although  the legal rights of Class A  and Class B shares will be identical,
the different expenses borne  by each class will  result in different net  asset
values  and dividends for the class.  Dividends will differ by approximately the
amount of the distribution expense  accrual differential among the classes.  The
net  asset value of  Class B shares will  generally be lower  than the net asset
value of the Class A shares as  a result of the distribution expense charged  to
Class B shares.
    
 
   
                            PERFORMANCE INFORMATION
    
 
   
    The  Fund may from time to time advertise total return for each class of the
Portfolios. THESE FIGURES ARE BASED ON HISTORICAL EARNINGS AND ARE NOT  INTENDED
TO INDICATE FUTURE PERFORMANCE. The "total return" shows what an investment in a
class  of the Portfolio would have earned  over a specified period of time (such
as one, five or ten years), assuming that all distributions and dividends by the
Portfolio were reinvested in the same class on the reinvestment dates during the
period. Total return  does not  take into account  any federal  or state  income
taxes that may be payable on dividends and distributions or upon redemption. The
Fund  may  also include  comparative performance  information in  advertising or
marketing the Portfolios' shares. Such performance information may include  data
from  Lipper Analytical  Services, Inc.,  other industry  publications, business
periodicals, rating services and market indices.
    
 
   
    The performance figures  for Class  B shares  will generally  be lower  than
those  for Class  A shares because  of the  distribution fee charged  to Class B
shares.
    
 
   
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
    
 
   
    All income dividends and capital gains  distributions for a class of  shares
will automatically be reinvested in additional shares of such class at net asset
value,  except that,  upon written  notice to  the Fund  or by  checking off the
appropriate box in the Distribution  Option Section on the Account  Registration
Form,  a shareholder  may elect  to receive  income dividends  and capital gains
distributions in cash. Each Portfolio expects to distribute substantially all of
its net  investment income  in the  form of  quarterly dividends.  Net  realized
gains,  if any,  after reduction for  any available tax  loss carryforwards will
also be distributed annually. Confirmations of the purchase
    
 
                                       28
<PAGE>
   
of shares  of  the  Portfolio  through  the  automatic  reinvestment  of  income
dividends  and capital  gains distributions will  be provided,  pursuant to Rule
10b-10(b) under the  Securities Exchange Act  of 1934, as  amended, on the  next
monthly  client  statement  following  such  purchase  of  shares. Consequently,
confirmations of such purchases will not  be provided at the time of  completion
of such purchases as might otherwise be required by Rule 10b-10.
    
 
   
    Undistributed  net investment income is included in a Portfolio's net assets
for the purpose  of calculating  net asset value  per share.  Therefore, on  the
"ex-dividend"  date, the net asset value  per share excludes the dividend (i.e.,
is reduced by  the per  share amount of  the dividend).  Dividends paid  shortly
after  the purchase  of shares by  an investor,  although in effect  a return of
capital, are taxable to shareholders subject to tax.
    
 
   
    Because of  the  distribution  fee  and  any  other  expenses  that  may  be
attributable  to the  Class B  shares, the  net income  attributable to  and the
dividends payable  on  Class  B  shares  will  be  lower  than  the  net  income
attributable  to and the dividends  payable on Class A  shares. As a result, the
net asset value per share of the classes of the Portfolios will differ at times.
Expenses of the  Portfolios allocated to  a particular class  of shares  thereof
will be borne on a pro rata basis by each outstanding share of that class.
    
 
   
                                     TAXES
    
 
   
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
    
 
   
    No  attempt has been made to present  a detailed explanation of the federal,
state, or  local  income tax  treatment  of  a Portfolio  or  its  shareholders.
Accordingly,  shareholders  are urged  to consult  their tax  advisors regarding
specific questions as to federal, state and local income taxes.
    
 
   
    Each Portfolio  is treated  as  a separate  entity  for federal  income  tax
purposes  and is not  combined with the Fund's  other portfolios. Each Portfolio
intends to qualify for the  special tax treatment afforded regulated  investment
companies  under Subchapter M of  the Internal Revenue Code  of 1986, as amended
(the "Code"), so that the  Portfolio will be relieved  of federal income tax  on
that  part of its net investment income and net capital gain that is distributed
to shareholders.
    
 
   
    Each Portfolio distributes  substantially all of  its net investment  income
(including,  for  this purpose,  net short-term  capital gain)  to shareholders.
Dividends from a Portfolio's net  investment income are taxable to  shareholders
as  ordinary  income, whether  received in  cash or  in additional  shares. Such
dividends  paid   by  a   Portfolio   will  generally   qualify  for   the   70%
dividends-received  deduction for  corporate shareholders  to the  extent of the
aggregate qualifying  dividend  income  received  by  the  Portfolio  from  U.S.
corporations.  Distributions of  net capital gain  (the excess  of net long-term
capital gain over net  short-term capital loss) are  taxable to shareholders  as
long-term  capital gain,  regardless of  how long  shareholders have  held their
shares. Each Portfolio  sends reports  annually to shareholders  of the  federal
income tax status of all distributions made during the preceding year.
    
 
   
    Each   Portfolio  intends   to  make  sufficient   distributions  or  deemed
distributions of its ordinary income and capital gain net income (the excess  of
short-term  and long-term  capital gains  over short-term  and long-term capital
losses), including any available capital  loss carry-forwards, prior to the  end
of each calendar year to avoid liability for federal excise tax.
    
 
                                       29
<PAGE>
   
    Dividends  and  other  distributions  declared by  a  Portfolio  in October,
November or December of any year and payable to shareholders of record on a date
in such month will be deemed to have been paid by the Portfolio and received  by
the  shareholders on December 31  of that year if  the distributions are paid by
the Portfolio at any time during the following January.
    
 
   
    The sale, exchange  or redemption of  shares may result  in taxable gain  or
loss  to  the  sellling,  exchanging or  redeeming  shareholder,  depending upon
whether the fair market value of the redemption proceeds exceeds or is less than
the shareholder's adjusted basis in the  redeemed, exchanged or sold shares.  If
capital  gain distributions have been made with  respect to shares that are sold
at a loss after being held for six months or less, then the loss is treated as a
long-term capital loss to the extent of the capital gain distributions.
    
 
   
    The conversion of Class A shares to  Class B shares should not be a  taxable
event to the shareholder.
    
 
   
    Shareholders  are urged  to consult with  their tax  advisors concerning the
application of state and local income taxes to investments in a Portfolio, which
may differ from the federal income tax consequences described above.
    
 
   
    THE  TAX  DISCUSSION  SET  FORTH  ABOVE  IS  INCLUDED  HEREIN  FOR   GENERAL
INFORMATION  ONLY. PROSPECTIVE INVESTORS  SHOULD CONSULT THEIR  OWN TAX ADVISERS
WITH RESPECT TO THE TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN A PORTFOLIO.
    
 
                             PORTFOLIO TRANSACTIONS
 
    The Investment  Advisory  Agreement authorizes  the  Adviser to  select  the
brokers  or  dealers that  will execute  the purchases  and sales  of investment
securities for each of the Fund's Portfolios and directs the Adviser to use  its
best  efforts to  obtain the best  available price and  most favorable execution
with respect to all transactions for the Portfolios. The Fund has authorized the
Adviser to pay higher commissions in recognition of brokerage services which, in
the opinion  of  the  Adviser,  are necessary  for  the  achievement  of  better
execution,  provided the Adviser believes this to be in the best interest of the
Fund.
 
    Since shares of the Portfolios are not marketed through intermediary brokers
or dealers, it  is not the  Fund's practice to  allocate brokerage or  principal
business  on the basis of sales of shares  which may be made through such firms.
However, the Adviser  may place portfolio  orders with qualified  broker-dealers
who  recommend the  Fund's Portfolios or  who act  as agents in  the purchase of
shares of the Fund's Portfolios for their clients.
 
    In purchasing and selling  securities for the Portfolios,  it is the  Fund's
policy to seek to obtain quality execution at the most favorable prices, through
responsible   broker-dealers.  In   selecting  broker-dealers   to  execute  the
securities transactions for the Portfolios, consideration will be given to  such
factors  as the price of the security, the  rate of the commission, the size and
difficulty of  the  order,  the  reliability,  integrity,  financial  condition,
general  execution and operational capabilities of competing broker-dealers, and
the brokerage  and  research services  which  they  provide to  the  Fund.  Some
securities  considered for investment by a Portfolio may also be appropriate for
other clients  served  by the  Adviser.  If a  purchase  or sale  of  securities
consistent  with the investment policies of a portfolio and one or more of these
other clients served by  the Adviser is  considered at or  about the same  time,
transactions  in such securities will be allocated among the portfolios and such
other clients
 
                                       30
<PAGE>
in a manner  deemed fair and  reasonable by  the Adviser. Although  there is  no
specified  formula  for  allocating such  transactions,  the  various allocation
methods used by the Adviser, and the results of such allocations, are subject to
periodic review by the Fund's Board of Directors.
 
    Subject to the overriding objective of obtaining the best possible execution
of orders,  the Adviser  may allocate  a portion  of the  Portfolio's  brokerage
transactions  to Morgan Stanley or broker affiliates of Morgan Stanley. In order
for Morgan Stanley or  its affiliates to effect  any portfolio transactions  for
the Fund, the commissions, fees or other remuneration received by Morgan Stanley
or such affiliates must be reasonable and fair compared to the commissions, fees
or  other  remuneration  paid to  other  brokers in  connection  with comparable
transactions  involving  similar  securities  being  purchased  or  sold  on   a
securities  exchange during a comparable period  of time. Furthermore, the Board
of Directors of  the Fund, including  a majority  of the Directors  who are  not
"interested  persons,"  as defined  in the  Investment Company  Act of  1940, as
amended (the "1940 Act") have  adopted procedures which are reasonably  designed
to  provide  that any  commissions, fees  or other  remuneration paid  to Morgan
Stanley or such affiliates be consistent with the foregoing standard.
 
    Portfolio securities will not  be purchased from or  through, or sold to  or
through,  the Adviser or Morgan Stanley  or any "affiliated persons," as defined
in the 1940 Act, of Morgan Stanley when such entities are acting as  principals,
except to the extent permitted by law.
 
   
    Although  none of  the Portfolios  intend to  invest for  short-term trading
purposes, investment securities may be sold from time to time without regard  to
the  length of time they  have been held. For  each Portfolio, it is anticipated
that, under normal circumstances,  the annual portfolio  turnover rate will  not
exceed   100%.   High  portfolio   turnover  involves   correspondingly  greater
transaction costs which will be borne  directly by the respective Portfolio.  In
addition,  high portfolio turnover may result  in more capital gains which would
be taxable to the shareholders of the respective Portfolio. The tables set forth
in "Financial Highlights" present the Portfolios' historical turnover rates.
    
 
   
                              GENERAL INFORMATION
    
 
   
DESCRIPTION OF COMMON STOCK
    
 
   
    The Fund  was organized  as a  Maryland corporation  on June  16, 1988.  The
Articles  of Incorporation, as amended and restated, permit the Fund to issue up
to 34 billion shares of common stock,  with $.001 par value per share.  Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number  of shares the  Fund is authorized  to issue without  the approval of the
shareholders of the  Fund. Subject  to the  notice period  to shareholders  with
respect  to shares held by shareholders, the Board of Directors has the power to
designate one or  more classes of  shares of  common stock and  to classify  and
reclassify  any  unissued shares  with respect  to such  classes. The  shares of
common stock of each  portfolio are currently classified  into two classes,  the
Class  A shares and the Class B  shares, except for the International Small Cap,
Money Market and  Municipal Money Market  Portfolios, which only  offer Class  A
shares.
    
 
   
    The   shares  of   each  Portfolio,  when   issued,  will   be  fully  paid,
nonassessable, fully transferable and  redeemable at the  option of the  holder.
The  shares have no preference as to conversion, exchange, dividends, retirement
or other features and have no  pre-emptive rights. The shares of each  Portfolio
have non-cumulative voting rights, which means that the holders of more than 50%
of  the  shares voting  for  the election  of Directors  can  elect 100%  of the
Directors if they choose to do so.  Persons or organizations owning 25% or  more
of the outstanding
    
 
                                       31
<PAGE>
   
shares  of a Portfolio may be presumed to  "control" (as that term is defined in
the 1940 Act) the  Portfolio. Under Maryland  law, the Fund  is not required  to
hold  an annual meeting of  its shareholders unless required  to do so under the
1940 Act.
    
 
REPORTS TO SHAREHOLDERS
 
    The transfer agent  of the  Fund will send  to its  shareholders annual  and
semiannual  reports; the  financial statements  appearing in  annual reports are
audited by independent  accountants. Monthly unaudited  portfolio data are  also
available from the Fund upon request.
 
    In  addition, the Adviser or its agent, as Transfer Agent, will send to each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
 
CUSTODIAN
 
    As of September  1, 1995, domestic  securities and cash  are held by  Chase,
which  replaced U.S.  Trust as  the Fund's domestic  custodian. Chase  is not an
affiliate of  the Adviser  or  the Distributor.  Morgan Stanley  Trust  Company,
Brooklyn,  New York ("MSTC"),  an affiliate of the  Adviser and the Distributor,
acts as the Fund's custodian for  foreign assets held outside the United  States
and  employs subcustodians  approved by  the Board of  Directors of  the Fund in
accordance with regulations of  the Securities and  Exchange Commission for  the
purpose  of providing  custodial services  for such  assets. MSTC  may also hold
certain domestic assets for  the Fund. For more  information on the  custodians,
see "General Information -- Custody Arrangements" in the Statement of Additional
Information.
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
    Chase   Global   Funds  Services   Company,   73  Tremont   Street,  Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
 
INDEPENDENT ACCOUNTANTS
 
    Price Waterhouse  LLP serves  as independent  accountants for  the Fund  and
audits its annual financial statements.
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       32
<PAGE>
<TABLE>
<CAPTION>
   
           MORGAN STANLEY INSTITUTIONAL FUND, INC.
           SMALL CAP VALUE EQUITY, VALUE EQUITY AND BALANCED PORTFOLIOS
           P.O. BOX 2798, BOSTON, MA 02208-2798

- ---------------------------------------------------------------------------------------------------------------

                           ACCOUNT REGISTRATION FORM
- ---------------------------------------------------------------------------------------------------------------
<S>                        <C>
ACCOUNT INFORMATION        If you need assistance in filling out this form     
Fill in where applicable   for the Morgan Stanley Institutional Fund, please   
                           contact your Morgan Stanley representative or call  
                           us toll free 1-(800)-548-7786. Please print all     
                           items except signature, and mail to the Fund at the
                           address above.

- ---------------------------------------------------------------------------------------------------------------
A)  REGISTRATION
    1. INDIVIDUAL            1. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
                                 First Name           Initial              Last Name
    2. JOINT TENANTS         2. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       (RIGHTS OF                First Name           Initial              Last Name
       SURVIVORSHIP            / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       PRESUMED UNLESS           First Name           Initial              Last Name
       TENANCY IN COMMON 
       IS INDICATED)      
- ---------------------------------------------------------------------------------------------------------------
    3. CORPORATIONS,        3.  / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       TRUSTS AND OTHERS       
       Please call the          / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       Fund for additional
       documents that may       / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       be required to set 
       up account and to 
       authorize transactions.

                                Type of / / INCORPORATED / / UNINCORPORATED / / PARTNERSHIP / / UNIFORM GIFT/TRANSFER TO MINOR 
                                Registration:                 ASSOCIATION                   (ONLY ONE CUSTODIAN AND MINOR PERMITTED)


                                / / TRUST __________________________________     / / OTHER (Specify) ______________________________
- ---------------------------------------------------------------------------------------------------------------
B)  MAILING ADDRESS         Street or P.O. Box / / / / / / / / / / / / / / / / / / / / / / / / / / / /

    Please fill in 
    completely, including   City / / / / / / / / / / / / / State / / / Zip / / / / / /-/ / / / / / / / 
    telephone number(s).
                            Home                                   Business
                            Telephone No./ / / /-/ / / /-/ / / / / Telephone No./ / / /-/ / / /-/ / / /
                            / / United States  / / Resident  / /Non-Resident Alien:
                                Citizen            Alien        Indicate Country of Residence _________
- ---------------------------------------------------------------------------------------------------------------
C)  TAXPAYER                PART 1. Enter your Taxpayer            IMPORTANT TAX INFORMATION 
    IDENTIFICATION          Identification Number. For most          You (as a payee) are required by
    NUMBER                  individual taxpayers, this is your     law to provide us (as payer) with
    If the account is in    Social Security Number.                your correct Taxpayer Identification
    more than one name,     TAXPAYER IDENTIFICATION NUMBER         Number. Accounts that have a missing
    CIRCLE THE NAME OF THE    / / / /-/ / / / / / / / /            or incorrect Taxpayer Identification
    PERSON WHOSE TAXPAYER               OR                         Number will be subject to backup
    IDENTIFICATION NUMBER       SOCIAL SECURITY NUMBER             withholding at a 31% rate on dividends,
    IS PROVIDED IN SECTION    / / / /-/ / /-/ / / / /              distributions and other payments.
    A) ABOVE. If no name      PART 2. BACKUP WITHHOLDING           If you have not provided us with
    is circled, the number    / / Check this box if you are        your correct taxpayer identification
    will be considered to be  NOT subject to Backup                number, you may be subject to 
    that of the last name     Withholding under the                a $50 penalty imposed by the Internal
    listed. For Custodian     provisions of Section                Revenue Service.
    account of a minor        3406(a)(1)(C) of the Internal          Backup withholding is not an
    (Uniform Gift/Transfer    Revenue Code.                        additional tax; the tax liability of
    to Minor Act), give the                                        persons subject to backup withholding
    Social Security Number                                         will be reduced by the amount of tax
    of the minor.                                                  withheld. If withholding results in
                                                                   an overpayment of taxes, a refund 
                                                                   may be obtained. You may be notified
                                                                   that you are subject to backup 
                                                                   withholding under Section 3406(a)(1)(C)
                                                                   of the Internal Revenue Code because you
                                                                   have underreported interest or dividends
                                                                   or you were required to but failed to
                                                                   file a return which would have included a
                                                                   reportable interest or dividend payment. IF
                                                                   YOU HAVE NOT BEEN SO NOTIFIED, CHECK THE
                                                                   BOX IN PART 2 AT LEFT.

- ---------------------------------------------------------------------------------------------------------------

D)  PORTFOLIO AND          For Purchase of the following Portfolio(s):     
    CLASS SELECTION        Small Cap Value Equity Portfolio            / / Class A Shares $____ / / Class B Shares $____
    (Class A shares        Value Equity Portfolio                      / / Class A Shares $____ / / Class B Shares $____
    minimum $500,000       Balanced Portfolio                          / / Class A Shares $____ / / Class B Shares $____
    for each Portfolio                                                      Total Initial Investment $_____________
    and Class B shares
    minimum $100,000 for
    each Portfolio).
    Please indicate
    Portfolio, class and
    amount.

- ---------------------------------------------------------------------------------------------------------------

E)  METHOD OF   Payment by:
    INVESTMENT  / / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND, INC.--PORTFOLIO NAME)
    Please
    indicate
    manner of   / / Exchange $____________ From________________       / / / / / / / / / / /-/ /
    payment.                                Name of Portfolio              Account No.

               / / Account previously established by: 

               / / Phone exchange / / Wire on___________________       / / / / / / / / / / / /-/ /
                                                          Date             Account No.            (Check
                                                                 (Previously assigned by the Fund) Digit)


<PAGE>

- ---------------------------------------------------------------------------------------------------------------

F)  DISTRIBUTION                                       Income dividends and capital gains distributions (if any) will
    OPTION                                             be reinvested in additional shares unless either box below is
                                                       checked.

                                                       / / Income dividends to be paid in cash, capital
                                                           gains distributions (if any) in shares.

                                                      / /  Income dividends and capital gains distributions
                                                           (if any) to be paid in cash.

- ---------------------------------------------------------------------------------------------------------------


G)  TELEPHONE                    / / I/we hereby authorize the Fund and its      ______________________   ________________
    REDEMPTION                       agents to honor any telephone requests      Name of COMMERCIAL Bank  Bank Account No.
    Please select at time of         to wire redemption proceeds to the            (Not Savings Bank)
    initial application if you       commercial bank indicated at right and/or 
    wish to redeem shares by         mail redemption proceeds to the name and                             ________________
    telephone. A SIGNATURE           address in which my/our fund account is                                 Bank ABA No.
    GUARANTEE IS REQUIRED IF         registered if such requests are believed 
    BANK ACCOUNT IS NOT              to be authentic.                           _________________________________________________
    REGISTERED IDENTICALLY TO    The Fund and the Fund's Transfer Agent will    Name(s) in which your BANK Account is Established
    YOUR FUND ACCOUNT.           employ reasonable procedures to confirm that
                                 instructions communicated by telephone are     _________________________________________________
    TELEPHONE REQUESTS FOR       genuine. These procedures include requiring                 Bank's Street Address
    REDEMPTIONS WILL NOT BE      the investor to provide certain personal
    HONORED UNLESS THE BOX IS    identification information at the time an      _________________________________________________
    CHECKED.                     account is opened and prior to effecting each  City                    State                Zip
                                 transaction requested by telephone. In addition,
                                 all telephone transaction requests will be recorded
                                 and investors may be required to provide additional
                                 telecopied written instructions of transaction
                                 requests. Neither the Fund nor the Transfer Agent will
                                 be responsible for any loss, liability, cost or expenses
                                 for following instructions received by telephone that
                                 it reasonably believes to be genuine.


- ---------------------------------------------------------------------------------------------------------------

H)  INTERESTED PARTY
    OPTION
    In addition to the account   _________________________________________________________________
    statement sent to my/our                                 Name
    registered address, I/we     _________________________________________________________________
    hereby authorize the fund    
    to mail duplicate            _________________________________________________________________
    statements to the name and                              Address
    address provided at right.
                                 _________________________________________________________________
                                  City                      State                     Zip Code

- ---------------------------------------------------------------------------------------------------------------

I)  DEALER 
    INFORMATION                  _______________________  _______________________________  ___________
                                 Representative Name          Representative No.             Branch No.

- ---------------------------------------------------------------------------------------------------------------

J)  SIGNATURE OF        The undersigned certify(ies)  that I/we  have full  authority and  legal
    ALL HOLDERS         capacity  to purchase and redeem shares of the Fund and affirm that I/we
    AND TAXPAYER        have received a current Prospectus  of the Morgan Stanley  Institutional
    CERTIFICATION       Fund,  Inc. and agree to  be bound by its  terms. UNDER THE PENALTIES OF
    Sign Here >         PERJURY, I/WE CERTIFY THAT THE INFORMATION PROVIDED IN SECTION C)
                        ABOVE IS TRUE, CORRECT AND COMPLETE.

                        (X)                                 (X)
                        __________________________________  ______________________________________
                        Signature                Date       Signature                  Date


                        (X)                                 (X)
                        __________________________________  ______________________________________
                        Signature                Date       Signature                  Date

- ---------------------------------------------------------------------------------------------------------------

    
</TABLE>

<PAGE>
                 (This page has been left blank intentionally.)
<PAGE>
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
 
  NO  DEALER, SALES  REPRESENTATIVE OR ANY  OTHER PERSON HAS  BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE  CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS  HAVING BEEN AUTHORIZED BY THE FUND  OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF  THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION  TO
ANY  PERSON TO WHOM  IT IS UNLAWFUL TO  MAKE SUCH OFFER  OR SOLICITATION IN SUCH
JURISDICTION.
 
                           --------------------------
 
                               TABLE OF CONTENTS
 
<TABLE>
<S>                                                 <C>
                                                    PAGE
                                                    ----
Fund Expenses.....................................    2
Financial Highlights..............................    4
Prospectus Summary................................    8
Investment Objectives and Policies................   12
Additional Investment Information.................   14
Investment Limitations............................   17
Management of the Fund............................   18
Purchase of Shares................................   21
Redemption of Shares..............................   25
Shareholder Services..............................   26
Valuation of Shares...............................   27
Performance Information...........................   28
Dividends and Capital Gains Distributions.........   28
Taxes.............................................   29
Portfolio Transactions............................   30
General Information...............................   31
Account Registration Form
</TABLE>
 
                        SMALL CAP VALUE EQUITY PORTFOLIO
                             VALUE EQUITY PORTFOLIO
                               BALANCED PORTFOLIO
 
                               PORTFOLIOS OF THE
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
 
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
 
- ---------------------------------
- ---------------------------------
- ---------------------------------
- ---------------------------------
<PAGE>
                 (This page has been left blank intentionally.)
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
     ----------------------------------------------------------------------
 
                      ACTIVE COUNTRY ALLOCATION PORTFOLIO
 
                               A PORTFOLIO OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
 
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
                                ----------------
 
   
    Morgan  Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company, or mutual fund, which offers redeemable shares in
a   series   of   diversified   and   non-diversified   investment    portfolios
("portfolios").   The  Fund   currently  consists   of  twenty-eight  portfolios
representing a  broad range  of  investment choices.  The  Fund is  designed  to
provide clients with attractive alternatives for meeting their investment needs.
This  prospectus (the  "Prospectus") pertains  to the  Class A  and the  Class B
shares of the Active Country Allocation Portfolio (the "Portfolio"). On  January
2,  1996, the Portfolio began offering two classes of shares, the Class A shares
and the Class B shares, except for the Money Market, Municipal Money Market  and
International  Small Cap Portfolios which only  offer Class A shares. All shares
of the Portfolio owned prior to January 2, 1996 were redesignated Class A shares
on January 2,  1996. The Class  A and Class  B shares currently  offered by  the
Portfolio  have  different minimum  investment  requirements and  fund expenses.
Shares of  the  portfolios are  offered  with no  sales  charge or  exchange  or
redemption fee (with the exception of the International Small Cap Portfolio).
    
 
   
    The ACTIVE COUNTRY ALLOCATION PORTFOLIO seeks long-term capital appreciation
by  investing in accordance with country weightings determined by the Adviser in
equity securities of non-U.S. issuers  which, in the aggregate, replicate  broad
country indices.
    
 
    The  Fund is designed  to meet the investment  needs of discerning investors
who place a premium on quality  and personal service. With Morgan Stanley  Asset
Management   Inc.  as   Adviser  and   Administrator  (the   "Adviser"  and  the
"Administrator"), and with Morgan Stanley & Co. Incorporated ("Morgan  Stanley")
as  Distributor, the  Fund makes available  to institutional and  high net worth
individual investors a series  of portfolios which  benefit from the  investment
expertise  and commitment to  excellence associated with  Morgan Stanley and its
affiliates.
 
   
    This Prospectus is designed to set forth concisely the information about the
Fund that a prospective investor should  know before investing and it should  be
retained  for future reference. The Fund  offers additional portfolios which are
described in other prospectuses and  under "Prospectus Summary" below. The  Fund
currently  offers the following portfolios:  (i) GLOBAL AND INTERNATIONAL EQUITY
- -- Active Country Allocation, Asian  Equity, Emerging Markets, European  Equity,
Global  Equity, Gold, International  Equity, International Magnum, International
Small Cap, Japanese Equity  and Latin American Portfolios;  (ii) U.S. EQUITY  --
Aggressive  Equity, Emerging  Growth, Equity  Growth, MicroCap,  Small Cap Value
Equity, U.S. Real  Estate and Value  Equity Portfolios; (iii)  EQUITY AND  FIXED
INCOME  -- Balanced Portfolio; (iv) FIXED INCOME -- Emerging Markets Debt, Fixed
Income,  Global  Fixed  Income,  High  Yield,  Mortgage-Backed  Securities   and
Municipal  Bond Portfolios; and  (v) MONEY MARKET --  Money Market and Municipal
Money Market Portfolios. Additional information about the Fund is contained in a
"Statement of Additional Information," dated May 1, 1996, which is  incorporated
herein   by  reference.  The   Statement  of  Additional   Information  and  the
prospectuses pertaining to the other portfolios  of the Fund are available  upon
request  and without charge  by writing or  calling the Fund  at the address and
telephone number set forth above.
    
 
   
 THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES AND
   EXCHANGE COMMISSION  OR  ANY STATE  SECURITIES  COMMISSION, NOR  HAS  THE
    SECURITIES  AND EXCHANGE COMMISSION OR  ANY STATE SECURITIES COMMISSION
     PASSED  UPON  THE  ACCURACY  OR  ADEQUACY  OF  THIS  PROSPECTUS.   ANY
     REPRESENTATION    TO   THE    CONTRARY   IS    A   CRIMINAL   OFFENSE.
    
 
   
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1996.
    
<PAGE>
                                 FUND EXPENSES
 
   
    The  following table illustrates the expenses and fees that a shareholder of
the Active Country Allocation Portfolio will incur:
    
 
   
<TABLE>
<CAPTION>
SHAREHOLDER TRANSACTION EXPENSES
- ------------------------------------------------------------------------------------------
<S>                                                                                         <C>
Maximum Sales Load Imposed on Purchases
  Class A.................................................................................        None
  Class B.................................................................................        None
Maximum Sales Load Imposed on Reinvested Dividends
  Class A.................................................................................        None
  Class B.................................................................................        None
Deferred Sales Load
  Class A.................................................................................        None
  Class B.................................................................................        None
Redemption Fees
  Class A.................................................................................        None
  Class B.................................................................................        None
Exchange Fees
  Class A.................................................................................        None
  Class B.................................................................................        None
</TABLE>
    
 
   
<TABLE>
<CAPTION>
ANNUAL FUND OPERATING EXPENSES
- ------------------------------------------------------------------------------------------
<S>                                                                                         <C>
 (AS A PERCENTAGE OF AVERAGE NET ASSETS)
Management Fee (Net of Fee Waiver)*
  Class A.................................................................................       0.27%
  Class B.................................................................................       0.27%
12b-1 Fees
  Class A.................................................................................        None
  Class B.................................................................................       0.25%
Other Expenses
  Class A.................................................................................       0.53%
  Class B.................................................................................       0.53%
                                                                                            -----------
Total Operating Expenses (Net of Fee Waivers)*
  Class A.................................................................................       0.80%
  Class B.................................................................................       1.05%
                                                                                            -----------
                                                                                            -----------
</TABLE>
    
 
- ------------------------
   
*The Adviser has  agreed to waive  its management fees  and/or to reimburse  the
 Portfolio,  if necessary, if such fees would cause the Portfolio's total annual
 operating expenses, as a percentage of average daily net assets, to exceed  the
 percentages set forth in the table above. Absent the fee waiver, the management
 fee  would be  0.65%. Absent the  fee waiver and/or  expense reimbursement, the
 Portfolio's total operating expenses  would be 1.18% of  the average daily  net
 assets  of the Class A shares and 1.43%  of the average daily net assets of the
 Class B shares. As a result of this reduction, the Management Fee stated  above
 is  lower than the contractual  fee stated under "Management  of the Fund." The
 Adviser reserves the right to terminate  any of its fee waivers and/or  expense
 reimbursements  at any time in its  sole discretion. For further information on
 Fund expenses, see "Management of the Fund."
    
 
                                       2
<PAGE>
   
    The purpose of the  table above is to  assist the investor in  understanding
the  various expenses that  an investor in  the Portfolio will  bear directly or
indirectly. The Class A expenses and fees for the Portfolio are based on  actual
figures  for the fiscal year  ended December 31, 1995.  The Class B expenses and
fees for the Portfolio are based  on estimates, assuming that the average  daily
net  assets of the Class  B shares of the  Portfolio will be $50,000,000. "Other
Expenses" include  Board  of  Directors'  fees  and  expenses,  amortization  of
organizational  costs, filing fees, professional  fees and costs for shareholder
reports. Due to  the continuous nature  of Rule  12b-1 fees, long  term Class  B
shareholders  may pay  more than the  equivalent of the  maximum front-end sales
charges otherwise  permitted by  the  Rules of  Fair  Practice of  the  National
Association of Securities Dealers, Inc. ("NASD").
    
 
    The  following  example illustrates  the expenses  that you  would pay  on a
$1,000 investment assuming (1) a 5% annual rate of return and (2) redemption  at
the  end of each time period.  As noted in the table  above, the Fund charges no
redemption fees  of  any kind.  The  following example  is  based on  the  total
operating expenses of the Portfolio after fee waivers.
 
   
<TABLE>
<CAPTION>
                                                                       1 YEAR       3 YEARS      5 YEARS     10 YEARS
                                                                     -----------  -----------  -----------  -----------
<S>                                                                  <C>          <C>          <C>          <C>
Active Country Allocation Portfolio
  Class A..........................................................   $       8    $      26    $      44    $      99
  Class B..........................................................          11           33           58          128
</TABLE>
    
 
    THIS  EXAMPLE SHOULD  NOT BE CONSIDERED  A REPRESENTATION OF  PAST OR FUTURE
EXPENSES OR  PERFORMANCE. ACTUAL  EXPENSES MAY  BE GREATER  OR LESS  THAN  THOSE
SHOWN.
 
    The  Fund intends  to comply  with all  state laws  that restrict investment
company expenses. Currently, the  most restrictive state  law requires that  the
aggregate  annual expenses  of an  investment company  shall not  exceed two and
one-half percent (2 1/2%) of  the first $30 million  of average net assets,  two
percent (2%) of the next $70 million of average net assets, and one and one-half
percent (1 1/2%) of the remaining net assets of such investment company.
 
    The  Adviser has agreed to a reduction in  the amounts payable to it, and to
reimburse the Portfolio,  if necessary, if  in any  fiscal year the  sum of  the
Portfolio's expenses exceeds the limit set by applicable state law.
 
                                       3
<PAGE>
                              FINANCIAL HIGHLIGHTS
 
   
    The  following table provides financial highlights for the Class A shares of
the  Portfolio  for  each  of  the  periods  presented.  The  audited  financial
highlights  for the Class A  shares for the fiscal  year ended December 31, 1995
are part of the Fund's financial statements which appear in the Fund's  December
31,  1995 Annual  Report to  Shareholders and which  are included  in the Fund's
Statement of Additional  Information. The Portfolio's  financial highlights  for
each  of the periods presented have been  audited by Price Waterhouse LLP, whose
unqualified report  thereon is  also  included in  the Statement  of  Additional
Information.  Additional  performance  information  for the  Class  A  shares is
included in the Annual  Report. The Annual Report  and the financial  statements
therein, along with the Statement of Additional Information, are available at no
cost  from the Fund at the address and  telephone number noted on the cover page
of this Prospectus. Financial highlights are  not available for the new Class  B
shares  since  they were  not offered  as  of December  31, 1995.  Subsequent to
October 31, 1992 (the Fund's prior fiscal year end), the Fund changed its fiscal
year end to December 31. The following information should be read in conjunction
with the financial statements and notes thereto.
    
 
                                       4
<PAGE>
                      ACTIVE COUNTRY ALLOCATION PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                      JANUARY 17,
                                         1992*        TWO MONTHS
                                      TO OCTOBER         ENDED
                                          31,        DECEMBER 31,              YEARS ENDED DECEMBER 31,
                                         1992            1992            1993            1994            1995
                                     -------------   -------------   -------------   -------------   -------------
<S>                                  <C>             <C>             <C>             <C>             <C>
NET ASSET VALUE, BEGINNING OF
 PERIOD............................  $   10.00       $    9.37       $        9.59   $       12.21   $       11.65
                                     -------------   -------------   -------------   -------------   -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)........       0.11            0.02                0.13            0.19            0.17
  Net Realized and Unrealized Gain/
   (Loss) on Investments...........      (0.74)           0.20                2.75           (0.25)           1.00
                                     -------------   -------------   -------------   -------------   -------------
  Total from Investment
   Operations......................      (0.63)           0.22                2.88           (0.06)           1.17
                                     -------------   -------------   -------------   -------------   -------------
DISTRIBUTIONS
  Net Investment Income............         --              --               (0.09)          (0.14)          (0.25)
  In Excess of Net Investment
   Income..........................         --              --               (0.08)             --           (0.10)
  Net Realized Gain................         --              --                  --           (0.36)          (0.84)
  In Excess of Net Realized Gain...         --              --               (0.09)             --              --
                                     -------------   -------------   -------------   -------------   -------------
  Total Distributions..............         --              --               (0.26)          (0.50)          (1.19)
                                     -------------   -------------   -------------   -------------   -------------
NET ASSET VALUE, END OF PERIOD.....  $    9.37       $    9.59       $       12.21   $       11.65   $       11.63
                                     -------------   -------------   -------------   -------------   -------------
                                     -------------   -------------   -------------   -------------   -------------
TOTAL RETURN.......................      (6.30)%          2.35%              30.72%          (0.52)%         10.57%
                                     -------------   -------------   -------------   -------------   -------------
                                     -------------   -------------   -------------   -------------   -------------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period
 (Thousands).......................  $  47,534       $  50,234       $     150,854   $     182,977   $     170,663
Ratio of Expenses to Average Net
 Assets (1)(2).....................       0.88%**         0.80%**             0.80%           0.80%           0.80%
Ratio of Net Investment Income to
 Average Net Assets (1)(2).........       2.32%**         1.22%**             1.29%           1.43%           1.26%
Portfolio Turnover Rate............         62%              2%               % 53            % 51            % 72
- ------------------------------
(1) Effect of voluntary expense
    limitation during the period:
     Per share benefit to net
      investment income............  $    0.03       $    0.01       $        0.05   $        0.03   $        0.05
     Ratios before expense
      limitation:
     Expenses to Average Net
      Assets.......................       1.58%**         1.70%**             1.33%           1.00%           1.18%
     Net Investment Income to
      Average Net Assets...........       1.62%**         0.32%**             0.76%           1.23%           0.88%
</TABLE>
    
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to receive a management  fee calculated at  an annual rate  of 0.65% of  the
    average daily net assets of the Portfolio. The Adviser has agreed to waive a
    portion of this fee and/or reimburse expenses of the Portfolio to the extent
    that  the  total operating  expenses of  the Portfolio  exceed 0.80%  of the
    average daily net  assets of the  Class A  shares and 1.05%  of the  average
    daily  net assets  of the Class  B shares.  In the period  ended October 31,
    1992, the two months ended December  31, 1992, and the years ended  December
    31,  1993,  1994  and  1995,  the  Adviser  waived  management  fees  and/or
    reimbursed expenses  totalling  $164,000, $72,000,  $552,000,  $367,000  and
    $618,000, respectively, for the Portfolio.
    
 
 * Commencement of Operations.
 
** Annualized.
 
                                       5
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
 
   
    The   Fund  consists  of  twenty-eight  portfolios,  offering  institutional
investors and high net  worth individual investors a  broad range of  investment
choices coupled with the advantages of a no-load mutual fund with Morgan Stanley
and  its affiliates providing customized  services as Adviser, Administrator and
Distributor. Each portfolio offers Class A shares and, except the  International
Small Cap, Money Market and Municipal Money Market Portfolios, also offers Class
B  shares. Each portfolio has its own investment objective and policies designed
to meet its specific goals. This Prospectus pertains to the Class A and Class  B
shares of the Active Country Allocation Portfolio.
    
 
    -The   ACTIVE   COUNTRY   ALLOCATION  PORTFOLIO   seeks   long-term  capital
     appreciation by investing in accordance with country weightings  determined
     by  the  Adviser in  equity securities  of non-U.S.  issuers which,  in the
     aggregate, replicate broad country indices.
 
   
    The other portfolios of the Fund  are described in other prospectuses  which
may be obtained from the Fund at the address and phone number noted on the cover
page  of this  Prospectus. The objectives  of these other  portfolios are listed
below:
    
 
    GLOBAL AND INTERNATIONAL EQUITY:
 
   
    -The  ASIAN  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation   by
     investing primarily in the equity securities of Asian issuers.
    
 
    -The  CHINA GROWTH PORTFOLIO seeks to provide long-term capital appreciation
     by investing primarily in the equity securities of issuers in The  People's
     Republic of China, Hong Kong and Taiwan.
 
    -The  EMERGING  MARKETS PORTFOLIO  seeks  long-term capital  appreciation by
     investing primarily in equity securities of emerging country issuers.
 
   
    -The EUROPEAN  EQUITY  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing primarily in the equity securities of European issuers.
    
 
   
    -The  GLOBAL  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing primarily  in the  equity securities  of issuers  throughout  the
     world, including United States issuers.
    
 
    -The  GOLD  PORTFOLIO  seeks  long-term  capital  appreciation  by investing
     primarily in equity securities of  foreign and domestic issuers engaged  in
     gold-related activities.
 
   
    -The  INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation by
     investing primarily in the equity securities of non-United States issuers.
    
 
   
    -The INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation  by
     investing  primarily in equity securities of non-U.S. issuers in accordance
     with EAFE  country  (as defined  in  "Investment Objectives  and  Policies"
     below) weightings determined by the Adviser.
    
 
   
    -The  INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital appreciation
     by investing  primarily  in  the equity  securities  of  non-United  States
     issuers with equity market capitalizations of less than $1 billion.
    
 
    -The  JAPANESE  EQUITY  PORTFOLIO seeks  long-term  capital  appreciation by
     investing primarily in equity securities of Japanese issuers.
 
    -The LATIN  AMERICAN  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing primarily in equity securities of Latin American issuers and debt
     securities   issued  or   guaranteed  by  Latin   American  governments  or
     governmental entities.
 
                                       6
<PAGE>
   
    US EQUITY:
    
    -The AGGRESSIVE  EQUITY PORTFOLIO  seeks capital  appreciation by  investing
     primarily in corporate equity and equity-linked securities.
 
    -The  EMERGING  GROWTH  PORTFOLIO seeks  long-term  capital  appreciation by
     investing primarily  in  growth-oriented  equity securities  of  small-  to
     medium-sized corporations.
 
    -The  EQUITY  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing  in  growth-oriented  equity  securities  of  medium  and   large
     capitalization companies.
 
    -The  MICROCAP PORTFOLIO  seeks long-term capital  appreciation by investing
     primarily in growth-oriented equity securities of small corporations.
 
    -The SMALL CAP VALUE EQUITY PORTFOLIO  seeks high long-term total return  by
     investing  in  undervalued  equity  securities  of  small-  to medium-sized
     companies.
 
    -The U.S.  REAL ESTATE  PORTFOLIO  seeks to  provide above  average  current
     income  and long-term capital appreciation by investing primarily in equity
     securities of companies in  the U.S. real  estate industry, including  real
     estate investment trusts.
 
    -The  VALUE EQUITY PORTFOLIO seeks high  total return by investing in equity
     securities which the  Adviser believes  to be undervalued  relative to  the
     stock market in general at the time of purchase.
 
    EQUITY AND FIXED INCOME:
    -The  BALANCED PORTFOLIO seeks high total return while preserving capital by
     investing in  a  combination of  undervalued  equity securities  and  fixed
     income securities.
 
    FIXED INCOME:
    -The  EMERGING MARKETS DEBT  PORTFOLIO seeks high  total return by investing
     primarily  in  debt  securities   of  government,  government-related   and
     corporate issuers located in emerging countries.
 
    -The  FIXED INCOME PORTFOLIO seeks to produce a high total return consistent
     with the preservation of capital by investing in a diversified portfolio of
     fixed income securities.
 
    -The GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real  rate
     of  return while preserving capital by investing in fixed income securities
     of issuers throughout the world, including United States issuers.
 
    -The HIGH YIELD PORTFOLIO seeks to  maximize total return by investing in  a
     diversified  portfolio of high  yield fixed income  securities that offer a
     yield above  that  generally available  on  debt securities  in  the  three
     highest rating categories of the recognized rating services.
 
    -The  MORTGAGE-BACKED SECURITIES PORTFOLIO seeks to  produce as high a level
     of current income  as is  consistent with  the preservation  of capital  by
     investing  primarily  in  a  variety  of  investment-grade  mortgage-backed
     securities.
 
    -The MUNICIPAL  BOND PORTFOLIO  seeks to  produce a  high level  of  current
     income  consistent with  the preservation  of principal  through investment
     primarily in municipal obligations,  the interest on  which is exempt  from
     federal income tax.
 
    MONEY MARKET:
    -The  MONEY MARKET PORTFOLIO  seeks to maximize  current income and preserve
     capital while maintaining  high levels  of liquidity  through investing  in
     high quality money market instruments with remaining maturities of one year
     or less.
 
                                       7
<PAGE>
    -The  MUNICIPAL MONEY MARKET PORTFOLIO  seeks to maximize current tax-exempt
     income and  preserve capital  while maintaining  high levels  of  liquidity
     through  investing in high-quality money  market instruments with remaining
     maturities of one year or less which are exempt from federal income tax.
 
INVESTMENT MANAGEMENT
 
   
    Morgan Stanley Asset Management  Inc., a wholly  owned subsidiary of  Morgan
Stanley  Group  Inc.,  which,  together  with  its  affiliated  asset management
companies, at December 31, 1995 had approximately $57.4 billion in assets  under
management  as  an  investment  manager  or  as  a  fiduciary  adviser,  acts as
investment adviser to the  Fund and each of  its portfolios. See "Management  of
the Fund -- Investment Adviser" and "Management of the Fund -- Administrator."
    
 
HOW TO INVEST
 
   
    Class  A shares of  the Portfolio are  offered directly to  investors at net
asset value with no  sales commission or  12b-1 charges. Class  B shares of  the
Portfolio  are offered at net  asset value with no  sales commission, but with a
12b-1 fee, which  is accrued daily  and paid  quarterly, equal to  0.25% of  the
Class B shares' average daily net assets on an annualized basis. Share purchases
may  be  made  by  sending  investments directly  to  the  Fund  or  through the
Distributor. Shares  in a  Portfolio account  opened prior  to January  2,  1996
(each,  a "Pre-1996 Account") were designated Class A shares on January 2, 1996.
For a Portfolio account opened  on or after January  2, 1996 (a "New  Account"),
the  minimum initial investment is $500,000 for  Class A shares and $100,000 for
Class B shares. Certain exceptions to the foregoing minimums apply to (1) shares
in a Pre-1996  Account with  a value of  $100,000 or  more on March  1, 1996  (a
"Grandfathered Class A Account"); (2) Portfolio accounts held by officers of the
Adviser  and  its  affiliates;  and (3)  certain  advisory  or  asset allocation
accounts, such as Total Funds Management accounts, managed by Morgan Stanley  or
its affiliates, including the Adviser ("Managed Accounts"). The Adviser reserves
the  right in its sole  discretion to determine which  of such advisory or asset
allocation accounts shall be Managed Accounts. For information regarding Managed
Accounts, please contact your Morgan Stanley account representative or the  Fund
at  the telephone number provided  on the cover of  this Prospectus. Shares in a
Pre-1996 Account  with  a value  of  less than  $100,000  on March  1,  1996  (a
"Grandfathered  Class B Account") converted to Class  B shares on March 1, 1996.
The minimum investment levels may be waived at the discretion of the Adviser for
(i) certain employees  and customers  of Morgan  Stanley or  its affiliates  and
certain   trust  departments,  brokers,  dealers,  agents,  financial  planners,
financial services  firms, or  investment  advisers that  have entered  into  an
agreement  with  Morgan  Stanley  or its  affiliates;  and  (ii)  retirement and
deferred compensation plans and trusts used  to fund such plans, including,  but
not  limited to, those defined in Section  401(a), 403(b) or 457 of the Internal
Revenue Code of 1986, as amended, and "rabbi trusts." See "Purchase of Shares --
Minimum Investment  and  Account Sizes;  Conversion  from  Class A  to  Class  B
Shares."
    
 
   
    The  minimum subsequent investment for a Portfolio account is $1,000 (except
for automatic  reinvestment of  dividends and  capital gains  distributions  for
which  there  is no  minimum). Such  subsequent investments  will be  applied to
purchase additional  shares  in  the same  class  held  by a  shareholder  in  a
Portfolio account. See "Purchase of Shares -- Additional Investments."
    
 
                                       8
<PAGE>
HOW TO REDEEM
 
   
    Class  A shares or  Class B shares of  the Portfolio may  be redeemed at any
time, without cost, at the net asset value per share of shares of the applicable
class next determined after  receipt of the  redemption request. The  redemption
price may be more or less than the purchase price. Certain redemptions may cause
involuntary  redemption or automatic conversion. Class  A or Class B shares held
in  New  Accounts   are  subject  to   involuntary  redemption  if   shareholder
redemption(s)  of such  shares reduces  the value of  such account  to less than
$100,000 for a continuous 60-day  period. Involuntary redemption does not  apply
to  Managed Accounts, Grandfathered  Class A Accounts  and Grandfathered Class B
Accounts, regardless of  the value of  such accounts.  Class A shares  in a  New
Account  will convert  to Class  B shares  if shareholder  redemption(s) of such
shares reduces the value of such account to less than $500,000 for a  continuous
60-day  period. Class B  shares in a  New Account will  automatically convert to
Class A shares if shareholder purchases  of additional Class B shares or  market
activity cause the value of the Class B shares in the New Account to increase to
$500,000  or  more.  See  "Purchase  of  Shares  --  Minimum  Account  Sizes and
Involuntary Redemption of Shares" and "Redemption of Shares."
    
 
RISK FACTORS
 
   
    The  investment  policies  of  the   Portfolio  entail  certain  risks   and
considerations  of which an investor should  be aware. The Portfolio will invest
in securities of foreign issuers, including issuers in emerging countries, which
are subject to certain risks not typically associated with domestic  securities,
including  (1) restrictions on foreign investment and on repatriation of capital
invested in  foreign  countries, (2)  currency  fluctuations, (3)  the  cost  of
converting  foreign currency into  U.S. dollars, (4)  potential price volatility
and lesser liquidity of shares traded  on foreign country securities markets  or
lack  of a secondary  trading market for  such securities and  (5) political and
economic risks, including the risk of nationalization or expropriation of assets
and the risk  of war.  In addition,  accounting, auditing,  financial and  other
reporting  standards in foreign  countries are not  equivalent to U.S. standards
and therefore, disclosure of  certain material information may  not be made  and
less  information may be  available to investors  investing in foreign countries
than in the United States. There is also generally less governmental  regulation
of  the  securities  industry  in  foreign  countries  than  the  United States.
Moreover, it may be more difficult to  obtain a judgment in a court outside  the
United   States.  See  "Investment  Objective   and  Policies"  and  "Additional
Investment Information." In  addition, the  Portfolio may  invest in  repurchase
agreements,  lend its portfolio securities, purchase securities on a when-issued
basis and  invest  in  forward  foreign currency  exchange  contracts  to  hedge
currency   risk  associated  with  investment  in  non-U.S.  dollar  denominated
securities. Each of  these investment strategies  involves specific risks  which
are   described  under  "Investment  Objective  and  Policies"  and  "Additional
Investment Information" herein and under "Investment Objectives and Policies" in
the Statement of Additional Information.
    
 
                                       9
<PAGE>
                       INVESTMENT OBJECTIVE AND POLICIES
 
    The investment  objective  of the  Active  Country Allocation  Portfolio  is
described  below, together with the policies the  Fund employs in its efforts to
achieve this  objective. The  Active Country  Allocation Portfolio's  investment
objective  is a fundamental policy which may not be changed without the approval
of a majority  of the  Portfolio's outstanding  voting securities.  There is  no
assurance  that  the Fund  will attain  its  objective. The  investment policies
described below  are  not  fundamental  policies  and  may  be  changed  without
shareholder approval.
 
    The  investment objective of  the Active Country  Allocation Portfolio is to
provide long-term capital appreciation by  investing in accordance with  country
weightings  determined by the  Adviser in equity  securities of non-U.S. issuers
which, in the aggregate, replicate broad country indices. The Adviser utilizes a
top-down approach in  selecting investments  for the  Portfolio that  emphasizes
country  selection and  weighting rather  than individual  stock selection. This
approach reflects  the  Adviser's philosophy  that  a diversified  selection  of
securities  representing  exposure to  world  markets, based  upon  the economic
outlook and current valuation  levels for each country,  is an effective way  to
maximize  the  return  and  minimize  the  risk  associated  with  international
investment.
 
   
    The Adviser determines country allocations  for the Portfolio on an  ongoing
basis  within policy ranges dictated by each country's market capitalization and
liquidity. The Portfolio will invest in the industrialized countries  throughout
the  world that comprise the Morgan  Stanley Capital International EAFE (Europe,
Australia and the Far  East) Index. The Portfolio  will also invest in  emerging
country  equity securities.  With respect to  the Portfolio,  the term "emerging
country" applies  to  any country  which,  in the  opinion  of the  Adviser,  is
generally   considered  to  be   an  emerging  or   developing  country  by  the
international  financial  community,  including   the  International  Bank   for
Reconstruction  and Development (more commonly known  as the World Bank) and the
International Finance Corporation. There are currently over 130 countries which,
in the  opinion of  the Adviser,  are  generally considered  to be  emerging  or
developing  countries by the international financial community, approximately 40
of which currently have stock  markets. These countries generally include  every
nation  in the  world except  the United  States, Canada,  Japan, Australia, New
Zealand and most nations located in Western Europe. Currently, investing in many
emerging countries is not feasible or may involve unacceptable political  risks.
The  Portfolio will focus its investments  on those emerging market countries in
which it believes the economies are developing strongly and in which the markets
are becoming more sophisticated.  With respect to the  portion of the  Portfolio
that  is invested in emerging country equity securities, the Portfolio initially
intends to invest primarily in some or all of the following countries:
    
 
<TABLE>
<S>              <C>
Argentina        Portugal
Brazil           Philippines
India            South Africa
Indonesia        South Korea
Malaysia         Thailand
Mexico           Turkey
</TABLE>
 
As markets  in other  countries develop,  the Portfolio  expects to  expand  and
further diversify the emerging countries in which it invests. The Portfolio does
not  intend to  invest in any  security in a  country where the  currency is not
freely convertible  to  U.S. dollars,  unless  the Portfolio  has  obtained  the
necessary governmental
 
                                       10
<PAGE>
licensing to convert such currency or other appropriately licensed or sanctioned
contractual guarantee to protect such investment against loss of that currency's
external  value, or the Portfolio  has a reasonable expectation  at the time the
investment is  made  that such  governmental  licensing or  other  appropriately
licensed or sanctioned guarantee would be obtained or that the currency in which
the  security is quoted would be freely  convertible at the time of any proposed
sale of the security by the Portfolio.
 
    An emerging country security is one issued by a company that, in the opinion
of the  Adviser, has  one or  more  of the  following characteristics:  (i)  its
principal  securities trading market is in an emerging country, (ii) alone or on
a consolidated basis it derives  50% or more of  its annual revenue from  either
goods produced, sales made or services performed in emerging countries; or (iii)
it  is organized under the  laws of, and has a  principal office in, an emerging
country. The  Adviser will  base determinations  as to  eligibility on  publicly
available  information  and  inquiries  made  to  the  companies.  (See "Foreign
Investment Risk  Factors and  Special Considerations"  for a  discussion of  the
nature of information publicly available for non-U.S. companies.)
 
    By  analyzing a variety of macroeconomic  and political factors, the Adviser
develops  fundamental  projections  on  interest  rates,  currencies,  corporate
profits and economic growth for each country. These country projections are used
then  to determine what  the Adviser believes to  be a fair  value for the stock
market of each  country. Discrepancies between  actual value and  fair value  as
determined  by the Adviser provide an expected return for each stock market. The
expected return is  adjusted by  currency return expectations  derived from  the
Adviser's  purchasing-power parity exchange rate model  to arrive at an expected
total return in  U.S. dollars.  The final  country allocation  decision is  then
arrived  at by considering the expected total return in light of various country
specific considerations such as market  size, volatility, liquidity and  country
risk.
 
    Within  a particular country,  investments are made  through the purchase of
equity securities which, in aggregate, replicate a broad market index, which  in
most  cases will be the Morgan Stanley Capital International index for the given
country. The Adviser  may overweight  or underweight  an industry  segment of  a
particular  index if it  concludes this would be  advantageous to the Portfolio.
With respect to the  Portfolio, equity securities  include common and  preferred
stock,  convertible  securities,  and  rights and  warrants  to  purchase common
stocks. Indexation  of the  Portfolio's stock  selection reduces  stock-specific
risk  through  diversification and  minimizes  transaction costs,  which  can be
substantial in foreign markets.
 
    Common stocks purchased for the Portfolio normally will be listed on a major
stock exchange in  the subject  country. The Portfolio  will not  invest in  the
stocks  of U.S. issuers. For a description of special considerations and certain
risks associated with investments in foreign issuers, see "Additional Investment
Information." The  Portfolio  may  temporarily reduce  its  equity  holdings  in
response  to adverse  market conditions and  invest in  domestic, Eurodollar and
foreign  short-term  money  market  instruments  for  defensive  purposes.   See
"Investment Objective and Policies" in the Statement of Additional Information.
 
   
    Any remaining assets of the Portfolio not invested as described above may be
invested  in  certain  securities or  obligations  as set  forth  in "Additional
Investment Information" below.
    
 
                                       11
<PAGE>
                       ADDITIONAL INVESTMENT INFORMATION
 
   
    FOREIGN INVESTMENT.   Investment in  obligations of foreign  issuers and  in
foreign  branches of domestic banks involves somewhat different investment risks
than those affecting obligations of U.S. issuers. There may be limited  publicly
available  information with respect to foreign  issuers, and foreign issuers are
not generally subject  to uniform accounting,  auditing and financial  standards
and requirements comparable to those applicable to domestic companies. There may
also  be  less  government  supervision  and  regulation  of  foreign securities
exchanges, brokers and listed companies than in the U.S. Many foreign securities
markets have substantially less volume than U.S. national securities  exchanges,
and  securities of some foreign  issuers are less liquid  and more volatile than
securities  of  comparable  U.S.   issuers.  Brokerage  commissions  and   other
transaction  costs on foreign securities exchanges  are generally higher than in
the U.S.  Dividends and  interest paid  by  foreign issuers  may be  subject  to
withholding  and  other foreign  taxes,  which may  decrease  the net  return on
foreign investments as compared to dividends and interest paid to the Portfolios
by domestic companies.  See "Taxes". Additional  risks include future  political
and  economic developments,  the possibility  that a  foreign jurisdiction might
impose or change  withholding taxes on  income payable with  respect to  foreign
securities,  possible seizure,  nationalization or expropriation  of the foreign
issuer or foreign deposits,  and the possible  adoption of foreign  governmental
restrictions such as exchange controls.
    
 
    Such investments in securities of foreign issuers are frequently denominated
in  foreign currencies, and since the  Portfolio may temporarily hold uninvested
reserves in bank deposits  in foreign currencies, the  value of the  Portfolio's
assets  as measured in U.S. dollars may  be affected favorably or unfavorably by
changes in currency rates and in exchange control regulations, and the Portfolio
may incur costs in connection with conversions between various currencies.
 
   
    FORWARD FOREIGN CURRENCY EXCHANGE CONTRACTS.   The Portfolio may enter  into
forward  foreign currency exchange  contracts, that provide  for the purchase or
sale of an amount of a specified foreign currency at a future date. Purposes for
which such  contracts may  be used  include protecting  against a  decline in  a
foreign  currency against the U.S. dollar  between the trade date and settlement
date when  the Portfolio  purchases or  sells securities,  locking in  the  U.S.
dollar  value  of dividends  declared on  securities held  by the  Portfolio and
generally protecting the U.S. dollar value  of securities held by the  Portfolio
against  exchange  rate  fluctuation.  Such  contracts may  also  be  used  as a
protective measure against the effects of fluctuating rates of currency exchange
and exchange control regulations. While such forward contracts may limit  losses
to  the Portfolio as a result of exchange rate fluctuation, they will also limit
any gains that may otherwise have been realized. See "Investment Objectives  and
Policies  -- Forward Foreign Currency Contracts"  in the Statement of Additional
Information.
    
 
   
    LOANS OF PORTFOLIO  SECURITIES.  The  Portfolio may lend  its securities  to
brokers, dealers, domestic and foreign banks or other financial institutions for
the purpose of increasing its net investment income. These loans must be secured
continuously  by cash or equivalent collateral or by a letter of credit at least
equal to the  market value  of the securities  loaned plus  accrued interest  or
income.  There may be risks of delay in  recovery of the securities or even loss
of rights  in  the  collateral  should  the  borrower  of  the  securities  fail
financially.  The  Portfolio will  not enter  into securities  loan transactions
exceeding, in the  aggregate, 33  1/3% of the  market value  of the  Portfolio's
total  assets.  For  more  detailed information  about  securities  lending, see
"Investment Objectives and Policies" in the Statement of Additional Information.
    
 
                                       12
<PAGE>
    MONEY MARKET INSTRUMENTS.   The Portfolio  is permitted to  invest in  money
market   instruments,  although  the  Portfolio  intends  to  stay  invested  in
securities satisfying its primary investment objective to the extent  practical.
The  Portfolio may  make money  market investments  pending other  investment or
settlement for  liquidity, or  in adverse  market conditions.  The money  market
investments permitted for the Portfolio include obligations of the United States
Government  and  its  agencies  and  instrumentalities;  obligations  of foreign
sovereignties;  other   debt  securities;   commercial  paper   including   bank
obligations;  certificates  of  deposit  (including  Eurodollar  certificates of
deposit); and repurchase agreements. For  more detailed information about  these
money  market investments,  see "Description of  Securities and  Ratings" in the
Statement of Additional Information.
 
    OPTIONS AND FUTURES.   The  Portfolio may  write (i.e.,  sell) covered  call
options  and covered put  options on portfolio securities.  By selling a covered
call option, the Portfolio would become obligated during the term of the  option
to  deliver the securities underlying the option should the option holder choose
to exercise the option before the  option's termination date. In return for  the
call  it has written, the  Portfolio will receive from  the purchaser (or option
holder) a premium which is the price of the option, less a commission charged by
a broker. The Portfolio will keep  the premium regardless of whether the  option
is  exercised.  By  selling  a  covered  put  option,  the  Portfolio  incurs an
obligation to buy the security underlying  the option from the purchaser of  the
put  at the option's exercise price at any time during the option period, at the
purchaser's  election  (certain  options  written  by  the  Portfolio  will   be
exercisable  by  the  purchaser only  on  a  specific date).  A  call  option is
"covered" if  the Portfolio  owns  the security  underlying  the option  it  has
written or has an absolute or immediate right to acquire the security by holding
a  call option on such security, or  maintains a sufficient amount of cash, cash
equivalents or liquid securities to purchase the underlying security. Generally,
a put option is "covered" if the Fund maintains cash, U.S. Government securities
or other high grade debt obligations equal to the exercise price of the  option,
or if the Fund holds a put option on the same underlying security with a similar
or higher exercise price.
 
    When  the Portfolio writes  covered call options, it  augments its income by
the premiums received and is thereby hedged to the extent of that amount against
a decline in the price of the underlying securities. The premiums received  will
offset  a  portion  of the  potential  loss  incurred by  the  Portfolio  if the
securities underlying the  options are  ultimately sold  by the  Portfolio at  a
loss.  However, during the option  period, the Portfolio has,  in return for the
premium on the option, given up  the opportunity for capital appreciation  above
the  exercise price should the market price of the underlying security increase,
but has retained the risk  of loss should the  price of the underlying  security
decline.
 
    The Portfolio will write covered put options to receive the premiums paid by
purchasers  (when the  Adviser wishes  to purchase  the security  underlying the
option at  a price  lower  than its  current market  price,  in which  case  the
Portfolio  will write the covered put at  an exercise price reflecting the lower
purchase price sought) and to close out a long put option position.
 
    The Portfolio  may  also purchase  put  or  call options  on  its  portfolio
securities.  When the Portfolio purchases a call option it acquires the right to
buy a designated security at a designated price (the "exercise price"), and when
the Portfolio purchases a put option it acquires the right to sell a  designated
security  at the exercise price, in each case on or before a specified date (the
"termination date"), which is  usually not more than  nine months from the  date
the  option is issued.  The Portfolio may  purchase call options  to close out a
covered call  position or  to protect  against an  increase in  the price  of  a
security   it   anticipates   purchasing.  The   Portfolio   may   purchase  put
 
                                       13
<PAGE>
options on securities which it holds in its portfolio to protect itself  against
a  decline in the value of the security. If the value of the underlying security
were to fall below the exercise price of the put purchased in an amount  greater
than  the premium paid for  the option, the Portfolio  would incur no additional
loss. The  Portfolio may  also purchase  put options  to close  out written  put
positions  in a  manner similar  to call  option closing  purchase transactions.
There are no other limits  on the Portfolio's ability  to purchase call and  put
options.
 
   
    The  Portfolio  may  enter into  futures  contracts and  options  on futures
contracts as a hedge against fluctuations in the price of a security it holds or
intends to  acquire, but  not for  speculation or  for achieving  leverage.  The
Portfolio  may also enter into futures transactions to remain fully invested and
to reduce transaction costs. The Portfolio may enter into futures contracts  and
options  on futures contracts provided that not  more than 5% of the Portfolio's
total assets at the time of entering into the contract or option is required  as
deposit to secure obligations under all such contracts and options, and provided
that  not more  than 20%  of the  Portfolio's total  assets in  the aggregate is
invested in options, futures contracts and options on futures contracts.
    
 
    The Portfolio  may  purchase and  write  call  and put  options  on  futures
contracts that are traded on any international exchange, traded over the counter
or  which  are synthetic  options or  futures  or equity  swaps, and  enter into
closing transactions  with respect  to  such options  to terminate  an  existing
position.  An option  on a  futures contract gives  the purchaser  the right (in
return for the premium  paid) to assume  a position in  the futures contract  (a
long  position if the option is  a call and a short  position if the option is a
put) at a specified exercise  price at any time during  the term of the  option.
The Portfolio will purchase and write options on futures contracts for identical
purposes  to  those set  forth  above for  the  purchase of  a  futures contract
(purchase of a call option or  sale of a put option)  and the sale of a  futures
contract  (purchase of a put option or sale of a call option), or to close out a
long or short position in futures contracts.
 
    The primary risks  associated with the  use of futures  and options are  (i)
imperfect  correlation between the change in market  value of the stocks held by
the Portfolio  and the  prices of  futures and  options relating  to the  stocks
purchased or sold by the Portfolio; and (ii) possible lack of a liquid secondary
market  for a futures  contract and the  resulting inability to  close a futures
position which could have an adverse impact on the Portfolio's ability to hedge.
In the opinion of the  Board of Directors, the risk  that the Portfolio will  be
unable  to close out a futures position or options contract will be minimized by
only entering into  futures contracts  or options transactions  for which  there
appears to be a liquid secondary market.
 
    REPURCHASE  AGREEMENTS.  The Portfolio  may enter into repurchase agreements
with brokers, dealers or  banks that meet the  credit guidelines adopted by  the
Fund's  Directors. In a repurchase agreement, the Portfolio buys a security from
a seller that has  agreed to repurchase  it at a mutually  agreed upon date  and
price, reflecting the interest rate effective for the term of the agreement. The
term of these agreements is usually from overnight to one week and never exceeds
one  year. Repurchase agreements may be viewed as a fully collateralized loan of
money by the Portfolio to the  seller. The Portfolio always receives  securities
with  a market  value at  least equal to  the purchase  price (including accrued
interest) as collateral  and this  value is maintained  during the  term of  the
agreement.  If  the  seller  defaults and  the  collateral  value  declines, the
Portfolio might  incur a  loss.  If bankruptcy  proceedings are  commenced  with
respect  to the seller,  the Portfolio's realization upon  the collateral may be
delayed or limited. The aggregate  of certain repurchase agreements and  certain
other investments is limited as set forth under "Investment Limitations."
 
                                       14
<PAGE>
    WHEN-ISSUED  AND DELAYED  DELIVERY SECURITIES.   The  Portfolio may purchase
securities on a  when-issued or  delayed delivery basis.  In such  transactions,
instruments  are bought with payment and delivery  taking place in the future in
order to secure what is considered to  be an advantageous yield or price at  the
time  of the transaction. Delivery of and  payment for these securities may take
as long as a month  or more after the date  of the purchase commitment but  will
take  place  no more  than 120  days after  the trade  date. The  Portfolio will
maintain with the Custodian  a separate account with  a segregated portfolio  of
high-grade  debt  securities  or cash  in  an  amount at  least  equal  to these
commitments. The payment obligation and the interest rates that will be received
are each fixed  at the  time the  Portfolio enters  into the  commitment and  no
interest  accrues to the  Portfolio until settlement. Thus,  it is possible that
the market value at  the time of  settlement could be higher  or lower than  the
purchase  price if  the general  level of  interest rates  has changed.  It is a
current policy  of  the Portfolio  not  to enter  into  when-issued  commitments
exceeding,  in the aggregate, 15%  of the market value  of the Portfolio's total
assets less liabilities other than the obligations created by these commitments.
 
                             INVESTMENT LIMITATIONS
 
    As a  diversified  investment  company,  the Portfolio  is  subject  to  the
following  limitations: (a) as to 75% of its total assets, the Portfolio may not
invest more than 5%  of its total  assets in the securities  of any one  issuer,
except  obligations  of  the  United  States  Government  and  its  agencies and
instrumentalities, and  (b) the  Portfolio may  not  own more  than 10%  of  the
outstanding voting securities of any one issuer.
 
   
    The  Portfolio also operates under  certain investment restrictions that are
deemed fundamental limitations and may be changed only with the approval of  the
holders  of a  majority of the  Portfolio's outstanding  shares. See "Investment
Limitations" in  the  Statement  of Additional  Information.  In  addition,  the
Portfolio  operates  under  certain  non-fundamental  investment  limitations as
described below and in  the Statement of  Additional Information. The  Portfolio
may  not  (i) enter  into repurchase  agreements  with more  than seven  days to
maturity if, as a result, more than  10% of the market value of the  Portfolio's
net assets would be invested in such repurchase agreements and other investments
for  which market  quotations are not  readily available or  which are otherwise
illiquid; (ii) borrow money,  except from banks  for extraordinary or  emergency
purposes,  and then only  in amounts up to  10% of the  value of the Portfolio's
total assets, taken  at cost at  the time of  borrowing; or purchase  securities
while  borrowings  exceed 5%  of  its total  assets;  (iii) mortgage,  pledge or
hypothecate any assets except in connection  with any such borrowing in  amounts
up  to 10% of the value of the  Portfolio's net assets at the time of borrowing;
(iv) invest in fixed time deposits with a duration of over seven calendar  days;
or  (v) invest in fixed time deposits with  a duration of from two business days
to seven calendar days if more than 10% of the Portfolio's total assets would be
invested in these deposits.
    
 
   
                             MANAGEMENT OF THE FUND
    
 
   
    INVESTMENT ADVISER.  Morgan Stanley Asset Management Inc. is the  Investment
Adviser  and Administrator of the  Fund and each of  its Portfolios. The Adviser
provides investment advice  and portfolio  management services,  pursuant to  an
Investment  Advisory Agreement  and, subject  to the  supervision of  the Fund's
Board  of  Directors,  makes  each  of  the  Portfolio's  day-to-day  investment
decisions,  arranges for the  execution of portfolio  transactions and generally
manages each of the Portfolio's investments. The Adviser is entitled to  receive
from  the Active Country Allocation Portfolio  an annual management fee, payable
quarterly, equal to 0.65% of the average daily net assets of the Portfolio.
    
 
                                       15
<PAGE>
   
    The fees of  the Portfolio,  which involves  international investments,  are
higher  than  those of  most  investment companies  but  comparable to  those of
investment companies  with  similar objectives.  The  Adviser has  agreed  to  a
reduction  in  the  fees  payable  to it  and  to  reimburse  the  Portfolio, if
necessary, if  such fees  would cause  total annual  operating expenses  of  the
Portfolio  to exceed 0.80% of the average daily net assets of the Class A shares
of the Portfolio and 1.05% of the average daily net assets of the Class B shares
of the Portfolio.
    
 
   
    The Adviser, with  principal offices  at 1221  Avenue of  the Americas,  New
York,  New  York  10020,  conducts a  worldwide  portfolio  management business,
providing a broad  range of portfolio  management services to  customers in  the
United  States and abroad. At December 31,  1995, the Adviser, together with its
affiliated   asset   management   companies,   managed   investments    totaling
approximately  $57.4 billion, including approximately $41.9 billion under active
management and  $15.5  billion as  Named  Fiduciary or  Fiduciary  Adviser.  See
"Management of the Fund" in the Statement of Additional Information.
    
 
   
    PORTFOLIO  MANAGERS.  BARTON  M. BIGGS, MADHAV DHAR,  FRANCINE J. BOVICH AND
ANN D. THIVIERGE. Barton Biggs has been  Chairman and a director of the  Adviser
since  1980 and a Managing  Director of Morgan Stanley since  1975. He is also a
director of Morgan  Stanley Group  Inc. and a  director and  officer of  several
registered  investment  companies  to  which  the  Adviser  and  certain  of its
affiliates provide investment  advisory services.  Mr. Biggs holds  a B.A.  from
Yale  University  and an  M.B.A.  from New  York  University. Madhav  Dhar  is a
Managing Director of Morgan Stanley. He joined  the Adviser in 1984 to focus  on
global  asset allocation  and investment  strategy and  now heads  the Adviser's
emerging markets group and  serves as the  group's principal portfolio  manager.
Mr.  Dhar also coordinates the Adviser's developing country funds effort and has
been involved  in  the launching  of  the Adviser's  country  funds. He  is  the
portfolio manager of the Fund's Emerging Markets Portfolio, the Emerging Markets
and  Global Equity Allocation  Funds of the  Morgan Stanley Fund,  Inc., and the
Morgan Stanley  Emerging Markets  Fund, Inc.  (a closed-end  investment  company
listed  on the  New York  Stock Exchange). Mr.  Dhar is  also a  director of the
Morgan Stanley Emerging  Markets Fund, Inc.  He holds a  B.S. (honors) from  St.
Stephens  College, Delhi University (India),  and an M.B.A. from Carnegie-Mellon
University. Francine Bovich joined  the Adviser as a  Principal in 1993. She  is
responsible  for product development, portfolio  management and communication of
the Adviser's  asset  allocation  strategy to  institutional  investor  clients.
Previously,  Ms. Bovich was a Principal and Executive Vice President of Westwood
Management Corp. ("Westwood"), a  registered investment adviser. Before  joining
Westwood,  she was a  Managing Director of  Citicorp Investment Management, Inc.
(now  Chancellor  Capital  Management),  where  she  was  responsible  for   the
Institutional  Investment  Management  group. Ms.  Bovich  began  her investment
career with  Banker's  Trust  Company.  She  holds  a  B.A.  in  Economics  from
Connecticut  College  and an  M.B.A. in  Finance from  New York  University. Ann
Thivierge is a Principal of the Adviser. She is a member of the Adviser's  asset
allocation  committee,  primarily representing  the  Total Fund  Management team
since its inception in 1991. Prior to joining the Adviser in 1986, she spent two
years at Edgewood  Management Company,  a privately  held investment  management
firm.  Ms. Thivierge holds a B.A.  in International Relations from James Madison
College, Michigan  State University,  and an  M.B.A. in  Finance from  New  York
University.
    
 
    ADMINISTRATOR.    The Adviser  also  provides the  Fund  with administrative
services pursuant to  an Administration Agreement.  The services provided  under
the  Administration Agreement are subject to the supervision of the Officers and
the Board of  Directors of  the Fund  and include  day-to-day administration  of
matters  related  to the  corporate existence  of the  Fund, maintenance  of its
records, preparation of reports, supervision of the Fund's arrangements with its
custodian  and  assistance  in  the  preparation  of  the  Fund's   registration
statements under
 
                                       16
<PAGE>
Federal  and State  laws. The  Administration Agreement  also provides  that the
Administrator, through its agents, will provide the Fund dividend disbursing and
transfer agent services.  For its services  under the Administration  Agreement,
the Fund pays the Adviser a monthly fee which on an annual basis equals 0.15% of
the average daily net assets of the Portfolio.
 
   
    Under  an agreement between  the Adviser and The  Chase Manhattan Bank, N.A.
("Chase"), Chase  provides certain  administrative services  to the  Fund. In  a
merger  completed on September 1, 1995, Chase succeeded to all of the rights and
obligations under the  U.S. Trust Administration  Agreement between the  Adviser
and  the United  States Trust  Company of New  York ("U.S.  Trust"), pursuant to
which U.S. Trust had  agreed to provide certain  administrative services to  the
Fund.  Pursuant  to  a  delegation  clause  in  the  U.S.  Trust  Administration
Agreement, U.S.  Trust delegated  its administration  responsibilities to  Chase
Global  Funds Services Company ("CGFSC"), formerly known as Mutual Funds Service
Company, which after the  merger with Chase  is a subsidiary  of Chase and  will
continue  to provide  certain administrative services  to the  Fund. The Adviser
supervises and  monitors such  administrative services  provided by  CGFSC.  The
services  provided  under  the  Administration  Agreement  and  the  U.S.  Trust
Administration Agreement are  also subject to  the supervision of  the Board  of
Directors  of the  Fund. The  Board of  Directors of  the Fund  has approved the
provision of services described above  pursuant to the Administration  Agreement
and  the U.S. Trust Administration  Agreement as being in  the best interests of
the Fund. CGFSC's business address  is 73 Tremont Street, Boston,  Massachusetts
02108-3913. For additional information regarding the Administration Agreement or
the  U.S. Trust  Administration Agreement, see  "Management of the  Fund" in the
Statement of Additional Information.
    
 
   
    LOCAL ADMINISTRATOR  FOR THE  PORTFOLIO.   The Portfolio  is required  under
Brazilian  law  to have  a local  administrator  in Brazil.  Unibanco-Uniao (the
"Brazilian Administrator"),  a Brazilian  corporation, acts  as the  Portfolio's
Brazilian  administrator  pursuant  to  an  agreement  with  the  Portfolio (the
"Brazilian  Administration  Agreement").  Under  the  Brazilian   Administration
Agreement,  the  Brazilian  Administrator  performs  various  services  for  the
Portfolio, including  effecting  the  registration of  the  Portfolio's  foreign
capital  with  the  Central  Bank  of  Brazil,  effecting  all  foreign exchange
transactions related to the Portfolio's investments in Brazil and obtaining  all
approvals  required for the Portfolio to  make remittances of income and capital
gains and  for  the repatriation  of  the Portfolio's  investments  pursuant  to
Brazilian  law. For its services, the  Brazilian Administrator is paid an annual
fee equal to  0.125% of the  Portfolio's average weekly  net assets invested  in
Brazil,  paid monthly.  The principal office  of the  Brazilian Administrator is
located at Avenida Eusebio Matoso, 891,  Sao Paulo, S.P., Brazil. The  Brazilian
Administration  Agreement is terminable upon six months' notice by either party.
The Brazilian Administrator may be replaced only by an entity authorized to  act
as  a  joint  manager of  a  managed  portfolio of  bonds  and  securities under
Brazilian law.
    
 
    DIRECTORS AND OFFICERS.  Pursuant  to the Fund's Articles of  Incorporation,
the  Board of Directors  decides upon matters  of general policy  and review the
actions of the Fund's  Adviser, Administrator and  Distributor. The Officers  of
the Fund conduct and supervise its daily business operations.
 
   
    DISTRIBUTOR.   Morgan  Stanley serves  as the  exclusive Distributor  of the
shares of  the Fund.  Under its  Distribution Agreement  with the  Fund,  Morgan
Stanley  sells shares  of the Fund  upon the  terms and at  the current offering
price described in this Prospectus. Morgan Stanley is not obligated to sell  any
certain number of shares of the Fund.
    
 
                                       17
<PAGE>
   
    The  Portfolio currently offers  only the classes of  shares offered by this
Prospectus. The Portfolio may in the future offer one or more classes of  shares
with  features, distribution expenses or other  expenses that are different from
those of the classes currently offered.
    
 
    The Fund has  adopted a Plan  of Distribution  with respect to  the Class  B
shares  pursuant to Rule 12b-1 under the  1940 Act (the "Plan"). Under the Plan,
the Distributor is entitled  to receive from the  Portfolio a distribution  fee,
which  is accrued  daily and  paid quarterly,  of 0.25%  of the  Class B shares'
average daily net  assets on  an annualized  basis. The  Distributor expects  to
reallocate  most of its  fee to its  investment representatives. The Distributor
may, in its discretion, voluntarily waive from  time to time all or any  portion
of  its distribution fee and each of the  Distributor and the Adviser is free to
make additional payments  out of  its own  assets to  promote the  sale of  Fund
shares,   including   payments  that   compensate  financial   institutions  for
distribution services or shareholder services.
 
    The Plan is designed to compensate the Distributor for its services, not  to
reimburse  the Distributor for its expenses,  and the Distributor may retain any
portion of the fee that it does not expend in fulfillment of its obligations  to
the Fund.
 
    EXPENSES.   The Portfolio  is responsible for payment  of certain other fees
and expenses  (including  legal  fees, accountants'  fees,  custodial  fees  and
printing  and mailing  costs) specified  in the  Administration and Distribution
Agreements.
 
                               PURCHASE OF SHARES
 
   
    Class A and Class B shares of the Portfolio may be purchased, without  sales
commission,  at the net asset  value per share next  determined after receipt of
the purchase order by the Portfolio. See "Valuation of Shares."
    
 
   
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
    
 
   
    For an account for the Portfolio opened on or after January 2, 1996 (a  "New
Account"),  the minimum initial investment and minimum account size are $500,000
for Class  A  shares and  $100,000  for Class  B  shares. Managed  Accounts  may
purchase Class A shares without being subject to such minimum initial investment
or  minimum account size  requirements for a Portfolio  account. Officers of the
Adviser and its affiliates are subject to the minimums for a Portfolio  account,
except  they may purchase Class B shares subject to a minimum initial investment
and minimum account size of $5,000 for a Portfolio account.
    
 
   
    If the value of a New Account containing Class A shares falls below $500,000
(but remains at  or above  $100,000) because of  shareholder redemption(s),  the
Fund  will  notify  the shareholder,  and  if  the account  value  remains below
$500,000 (but remains at or above $100,000) for a continuous 60-day period,  the
Class  A shares  in such  account will  convert to  Class B  shares and  will be
subject to the  distribution fee and  other features applicable  to the Class  B
shares.  The Fund, however,  will not convert  Class A shares  to Class B shares
based solely upon  changes in  the market  that reduce  the net  asset value  of
shares.  Under  current tax  law, conversions  between share  classes are  not a
taxable event to the shareholder.
    
 
   
    Shares in a Portfolio account opened  prior to January 2, 1996 (a  "Pre-1996
Account")  were  designated Class  A  shares on  January  2, 1996.  Shares  in a
Pre-1996 Account  with  a  value  of  $100,000 or  more  on  March  1,  1996  (a
"Grandfathered  Class A Account") remained Class  A shares regardless of account
size thereafter. Except
    
 
                                       18
<PAGE>
   
for shares in a Managed  Account, shares in a Pre-1996  Account with a value  of
less  than  $100,000  on  March  1, 1996  (a  "Grandfathered  Class  B Account")
converted to Class B shares on March 1, 1996. Grandfathered Class A Accounts and
Managed Accounts are not subject  to conversion from Class  A shares to Class  B
shares.
    
 
   
    Investors  may also invest in the Fund  by purchasing shares through a trust
department, broker, dealer, agent, financial planner, financial services firm or
investment adviser.  An  investor  may  be  charged  an  additional  service  or
transaction fee by that institution. The minimum investment levels may be waived
at  the discretion  of the  Adviser for (i)  certain employees  and customers of
Morgan Stanley  or  its  affiliates  and  certain  trust  departments,  brokers,
dealers,  agents, financial  planners, financial  services firms,  or investment
advisers that  have  entered  into  an agreement  with  Morgan  Stanley  or  its
affiliates;  and (ii) retirement and deferred compensation plans and trusts used
to fund such  plans, including,  but not limited  to, those  defined in  Section
401(a),  403(b) or  457 of the  Internal Revenue  Code of 1986,  as amended, and
"rabbi trusts." Broker-dealers who make purchases for their customers may charge
a fee for such services.
    
 
   
    The Fund reserves the right to  modify or terminate the conversion  features
of the shares as stated above at any time upon 60-days' notice to shareholders.
    
 
   
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
    
 
   
    If  the value of a  New Account falls below  $100,000 because of shareholder
redemption(s), the Fund will  notify the shareholder, and  if the account  value
remains  below  $100,000 for  a  continuous 60-day  period,  the shares  in such
account are subject to redemption  by the Fund and,  if redeemed, the net  asset
value  of  such shares  will  be promptly  paid  to the  shareholder.  The Fund,
however, will not  redeem shares based  solely upon changes  in the market  that
reduce the net asset value of shares.
    
 
   
    For  purposes of redemptions by the Fund, the foregoing minimum account size
requirements do not  apply to  New Accounts containing  Class B  shares held  by
officers of the Adviser or its affiliates. However, if the value of such account
held  by an officer of the Adviser  or its affiliates falls below $5,000 because
of shareholder redemption(s), the Fund will  notify the shareholder, and if  the
account  value remains $5,000 for a continuous 60-day period, the shares in such
account are subject to redemption  by the Fund and,  if redeemed, the net  asset
value of such shares will be promptly paid to the shareholder.
    
 
   
    Grandfathered  Class A Accounts, Grandfathered  Class B Accounts and Managed
Accounts are not subject to involuntary redemption.
    
 
   
    The  Fund  reserves  the  right  to  modify  or  terminate  the  involuntary
redemption  features of  the shares  as stated above  at any  time upon 60-days'
notice to shareholders.
    
 
   
CONVERSION FROM CLASS B TO CLASS A SHARES
    
 
   
    If the value of Class B shares in a Portfolio account increases, whether due
to shareholder share  purchases or  market activity,  to $500,000  or more,  the
Class  B shares  will convert  to Class  A Shares.  Under current  tax law, such
conversion is not a taxable event  to the shareholder. Class A shares  converted
from  Class B shares are  subject to the same  minimum account size requirements
that are applicable to New Accounts containing Class A shares, as stated  above.
The  Fund reserves the right  to modify or terminate  this conversion feature at
any time upon 60-days' notice to shareholders.
    
 
                                       19
<PAGE>
   
INITIAL PURCHASES DIRECTLY FROM THE FUND
    
 
   
    The Fund's determination of an investor's eligibility to purchase shares  of
a  given class will  take precedence over  the investor's selection  of a class.
Assuming the investor is eligible for the  class, the Fund will select the  most
favorable class for the investor, if the investor has not done so.
    
 
INITIAL INVESTMENTS
 
1) BY  CHECK.   An account may  be opened  by completing and  signing an Account
   Registration Form and mailing it, together with a check ($500,000 minimum for
   Class A  shares of  the Portfolio  and $100,000  for Class  B shares  of  the
   Portfolio,  with certain exceptions  for Morgan Stanley  employees and select
   customers) payable  to "Morgan  Stanley Institutional  Fund, Inc.  --  Active
   Country Allocation Portfolio", to:
 
      Morgan Stanley Institutional Fund, Inc.
      P.O. Box 2798
      Boston, Massachusetts 02208-2798
 
   
     Payment will  be accepted only  in U.S. dollars,  unless prior approval for
  payment by other currencies is given by  the Fund. The Class(es) of shares  of
  the Portfolio to be purchased should be designated on the Account Registration
  Form.  For purchases  by check, the  Fund is ordinarily  credited with Federal
  Funds within  one business  day. Thus  your  purchase of  shares by  check  is
  ordinarily  credited to your account  at the net asset  value per share of the
  Portfolio determined on the next business day after receipt.
    
 
2) BY FEDERAL  FUNDS WIRE.   Purchases  may be  made by  having your  bank  wire
   Federal  Funds to the Fund's bank account.  In order to ensure prompt receipt
   of your Federal Funds Wire, it is important that you follow these steps:
 
   
A.  Telephone  the Fund  (toll free: 1-800-548-7786)  and provide  us with  your
    name,  address,  telephone  number, Social  Security  or  Tax Identification
    Number, the  portfolio(s) selected,  the class  selected, the  amount  being
    wired,  and by  which bank.  We will  then provide  you with  a Fund account
    number. (Investors with existing accounts should also notify the Fund  prior
    to wiring funds.)
    
 
   
B.    Instruct  your  bank to  wire  the  specified amount  to  the  Fund's Wire
    Concentration Bank Account (be  sure to have your  bank include the name  of
    the  portfolio(s)  selected,  the  class  selected  and  the  account number
    assigned to you) as follows:
    
 
   
    Chase Manhattan Bank, N.A.
    One Manhattan Plaza
    New York, NY 10081-1000
    ABA #021000021
    DDA #910-2-733293
    Attn: Morgan Stanley Institutional Fund, Inc.
    Ref: (Portfolio name, your account number, your account name)
    
 
    Please call the Fund at 1-800-548-7786 prior to wiring funds.
 
C.  Complete and sign the Account  Registration Form and mail it to the  address
    shown thereon.
 
                                       20
<PAGE>
  Purchase  orders for shares of  the Portfolio which are  received prior to the
  regular close of the NYSE (currently 4:00 p.m. Eastern Time) will be  executed
  at  the price computed  on the date of  receipt as long  as the Transfer Agent
  receives payment by check or  in Federal Funds prior  to the regular close  of
  the NYSE on such day.
 
   
  Federal Funds purchase orders will be accepted only on a day on which the Fund
  and Chase (the "Custodian Bank") are open for business. Your bank may charge a
  service fee for wiring Federal Funds.
    
 
3) BY  BANK WIRE.   The  same procedure outlined  under "By  Federal Funds Wire"
   above must be  followed in  purchasing shares  by bank  wire. However,  money
   transferred  by bank wire may or may  not be converted into Federal Funds the
   same day, depending on the time the  money is received and the bank  handling
   the  wire. Prior to such conversion, an investor's money will not be invested
   and, therefore, will not be earning dividends. Your bank may charge a service
   fee for wiring funds.
 
ADDITIONAL INVESTMENTS
 
   
    You may  add to  your account  at any  time (minimum  additional  investment
$1,000,  except  for  automatic  reinvestment  of  dividends  and  capital gains
distributions for which there are no minimums) by purchasing shares at net asset
value by mailing a check to  the Fund (payable to "Morgan Stanley  Institutional
Fund,  Inc. -- Active Country Allocation Portfolio")  at the above address or by
wiring monies to the Custodian Bank as outlined above. It is very important that
your account name, the portfolio name and the class selected be specified in the
letter or wire to assure  proper crediting to your  account. In order to  ensure
that  your wire orders are invested promptly, you are requested to notify one of
the Fund's representatives  (toll-free 1-800-548-7786) prior  to the wire  date.
Additional investments will be applied to purchase additional shares in the same
class held by a shareholder in a Portfolio account.
    
 
OTHER PURCHASE INFORMATION
 
    The purchase price of the Class A and Class B shares of the Portfolio is the
net  asset value next determined after the  order is received. See "Valuation of
Shares." An order received  prior to the  close of the  New York Stock  Exchange
("NYSE"),  which is currently  4:00 p.m. Eastern  Time, will be  executed at the
price computed on the date of receipt; an order received after the close of  the
NYSE  will be executed at the price computed on the next day the NYSE is open as
long as the Transfer Agent receives payment  by check or in Federal Funds  prior
to the regular close of the NYSE on such day.
 
   
    Although  the legal rights of Class A  and Class B shares will be identical,
the different expenses borne  by each class will  result in different net  asset
values  and dividends. The net  asset value of Class  B shares will generally be
lower than the net asset value of Class A shares as a result of the distribution
expense charged to Class B shares. It  is expected, however, that the net  asset
value  per share of the two classes  will tend to converge immediately after the
recording of dividends  which will  differ by  approximately the  amount of  the
distribution expense accrual differential between the classes.
    
 
    In  the interest  of economy and  convenience, and because  of the operating
procedures of the Fund, certificates  representing shares of the Portfolio  will
not  be issued. All shares  purchased are confirmed to  you and credited to your
account on the Fund's books  maintained by the Adviser  or its agents. You  will
have  the  same  rights  and  ownership  with  respect  to  such  shares  as  if
certificates had been issued.
 
                                       21
<PAGE>
    To ensure that checks are collected by the Fund, withdrawals of  investments
made  by check are  not presently permitted  until payment for  the purchase has
been received,  which may  take up  to eight  business days  after the  date  of
purchase.  As a condition  of this offering,  if a purchase  is cancelled due to
nonpayment or because your check does not clear, you will be responsible for any
loss the Fund or its  agents incur. If you are  already a shareholder, the  Fund
may  redeem shares from your account(s) to  reimburse the Fund or its agents for
any loss. In addition,  you may be prohibited  or restricted from making  future
investments in the Fund.
 
   
    Investors  may  also invest  in the  Fund by  purchasing shares  through the
Distributor.
    
 
   
EXCESSIVE TRADING
    
 
   
    Frequent  trades  involving  either   substantial  portfolio  assets  or   a
substantial  portion of your  account or accounts controlled  by you can disrupt
management of a portfolio and raise its expenses. Consequently, in the  interest
of  all the stockholders  of the Portfolio and  the Portfolio's performance, the
Fund may in its discretion bar  a stockholder that engages in excessive  trading
of  shares of any class  of a portfolio from further  purchases of shares of the
Fund for an indefinite period. The  Fund considers excessive trading to be  more
than  one purchase and sale involving shares of the same class of a portfolio of
the Fund within any 120-day period. As an example,
exchanging shares of  portfolios of  the Fund  as follows  amounts to  excessive
trading:  exchanging  Class  A shares  of  Portfolio  A for  Class  A  shares of
Portfolio B, then exchanging Class A shares of Portfolio B for Class A shares of
Portfolio C and  again exchanging  Class A  shares of  Portfolio C  for Class  A
shares  of Portfolio B  within a 120-day  period. Two types  of transactions are
exempt from these excessive trading restrictions: (1) trades exclusively between
money market  portfolios;  and (2)  trades  done  in connection  with  an  asset
allocation  service, such as TFM Accounts, managed or advised by MSAM and/or any
of its affiliates.
    
 
   
                              REDEMPTION OF SHARES
    
 
   
    You may  withdraw all  or  any portion  of the  amount  in your  account  by
redeeming  shares at any time. Please note  that purchases made by check are not
permitted to be redeemed until payment of the purchase has been collected, which
may take up to eight business days after purchase. The Fund will redeem Class  A
shares or Class B shares of the Portfolio at the next determined net asset value
of  shares of the applicable class. On days that both the NYSE and the Custodian
Bank are open for business,  the net asset value per  share of the Portfolio  is
determined  at the  close of  trading of the  NYSE (currently  4:00 p.m. Eastern
Time). Shares of the Portfolio may be  redeemed by mail or telephone. No  charge
is  made for redemption.  Any redemption proceeds  may be more  or less than the
purchase price of  your shares  depending on,  among other  factors, the  market
value of the investment securities held by the Portfolio.
    
 
   
BY MAIL
    
 
   
    The  Portfolio will redeem its  Class A shares or Class  B shares at the net
asset value determined on the  date the request is  received, if the request  is
received  in "good  order" before  the regular close  of the  NYSE. Your request
should be addressed to Morgan Stanley  Institutional Fund, Inc., P.O. Box  2798,
Boston,  Massachusetts 02208-2798,  except that deliveries  by overnight courier
should be addressed to Morgan Stanley Institutional Fund, Inc., c/o Chase Global
Funds Services Company, 73 Tremont Street, Boston, Massachusetts 02108-3913.
    
 
                                       22
<PAGE>
   
    "Good order"  means that  the  request to  redeem  shares must  include  the
following documentation:
    
 
   
        (a)   A letter of instruction or a stock assignment specifying the class
    and number  of  shares  or dollar  amount  to  be redeemed,  signed  by  all
    registered  owners  of the  shares  in the  exact  names in  which  they are
    registered;
    
 
        (b)  Any  required   signature  guarantees   (see  "Further   Redemption
    Information" below); and
 
        (c)    Other supporting  legal documents,  if required,  in the  case of
    estates, trusts,  guardianships, custodianships,  corporations, pension  and
    profit-sharing plans and other organizations.
 
    Shareholders who are uncertain of requirements for redemption should consult
with a Morgan Stanley Institutional Fund representative.
 
BY TELEPHONE
 
    Provided  you have previously elected the Telephone Redemption Option on the
Account Registration  Form, you  can  request a  redemption  of your  shares  by
calling  the Fund  and requesting  the redemption proceeds  be mailed  to you or
wired to your bank.  Please contact one of  Morgan Stanley Institutional  Fund's
representatives  for further details. In times of drastic market conditions, the
telephone redemption option  may be  difficult to implement.  If you  experience
difficulty in making a telephone redemption, your request may be made by mail or
overnight courier and will be implemented at the net asset value next determined
after  it is received. Redemption requests sent to the Fund through express mail
must be mailed  to the  address of the  Dividend Disbursing  and Transfer  Agent
listed  under "General Information." The Fund and the Fund's transfer agent (the
"Transfer  Agent")  will  employ  reasonable  procedures  to  confirm  that  the
instructions  communicated by  telephone are  genuine. These  procedures include
requiring the investor to provide certain personal identification information at
the time an account is opened and prior to effecting each transaction  requested
by  telephone. In addition, all telephone  transaction requests will be recorded
and  investors  may  be  required  to  provide  additional  telecopied   written
instructions  regarding transaction requests. Neither  the Fund nor the Transfer
Agent will be responsible for any loss, liability, cost or expense for following
instructions received by telephone that either of them reasonably believes to be
genuine.
 
    To change the commercial  bank or account  designated to receive  redemption
proceeds,  a written  request must  be sent  to the  Fund at  the address above.
Requests to change the bank  or account must be  signed by each shareholder  and
each signature must be guaranteed.
 
FURTHER REDEMPTION INFORMATION
 
    Normally  the  Fund will  make payment  for all  shares redeemed  within one
business day of receipt  of the request,  but in no event  will payment be  made
more  than  seven days  after receipt  of  a redemption  request in  good order.
However, payments to investors  redeeming shares which  were purchased by  check
will  not be made until  payment for the purchase  has been collected, which may
take up to eight days after the date of purchase. The Fund may suspend the right
of redemption or postpone the date upon which redemptions are effected at  times
when  the NYSE is closed, or under  any emergency circumstances as determined by
the Securities and Exchange Commission (the "Commission").
 
    If the Board  of Directors determines  that it would  be detrimental to  the
best  interests of the  remaining shareholders of the  Portfolio to make payment
wholly   or   partly   in    cash,   the   Fund    may   pay   the    redemption
 
                                       23
<PAGE>
proceeds in whole or in part by a distribution in-kind of securities held by the
Portfolio in lieu of cash in conformity with applicable rules of the Commission.
Distributions-in-Kind  will be made in  readily marketable securities. Investors
may incur brokerage charges on the  sale of portfolio securities so received  in
payment of redemptions.
 
    To  protect  your account,  the Fund  and its  agents from  fraud, signature
guarantees are required for  certain redemptions to verify  the identity of  the
person  who has  authorized a redemption  from your account.  Please contact the
Fund for further  information. See "Redemption  of Shares" in  the Statement  of
Additional Information.
 
                              SHAREHOLDER SERVICES
 
   
EXCHANGE FEATURES
    
 
   
    You  may exchange  shares that you  own in  the Portfolio for  shares of any
other available  portfolio of  the  Fund (other  than the  International  Equity
Portfolio,  which is  closed to  new investors). In  exchanging for  shares of a
portfolio with more  than one  class, the  class of  shares you  receive in  the
exchange  will be determined in the same  manner as any other purchase of shares
and will not  be based  on the  class of  shares surrendered  for the  exchange.
Consequently,  the same minimum initial investment  and minimum account size for
determining the  class  of shares  received  in  the exchange  will  apply.  See
"Purchase  of Shares."  Shares of  the portfolios  may be  exchanged by  mail or
telephone. The privilege to exchange shares  by telephone is automatic and  made
available  without shareholder election. Before you make an exchange, you should
read the prospectus of the portfolio(s) in which you seek to invest. Because  an
exchange  transaction  is treated  as a  redemption followed  by a  purchase, an
exchange would be considered  a taxable event for  shareholders subject to  tax.
The  exchange privilege  is only available  with respect to  portfolios that are
registered for  sale  in  a  shareholder's  state  of  residence.  The  exchange
privilege  may be modified or  terminated by the Fund  at any time upon 60-days'
notice to shareholders.
    
 
   
BY MAIL
    
 
   
    In order to  exchange shares  by mail, you  should include  in the  exchange
request  the  name and  account  number of  the  Portfolio, the  name(s)  of the
portfolio(s) and class(es) of shares into  which you intend to exchange  shares,
and  the signatures of all registered account holders. Send the exchange request
to  Morgan  Stanley  Institutional  Fund,  Inc.,  P.O.  Box  2798,  Boston,   MA
02208-2798.
    
 
   
BY TELEPHONE
    
 
   
    When  exchanging shares by  telephone, have ready the  name, class of shares
and account number of the current  portfolio, the names of the portfolio(s)  and
class(es)  of  shares into  which  you intend  to  exchange shares,  your Social
Security number  or Tax  I.D. number,  and your  account address.  Requests  for
telephone  exchanges received prior to 4:00 p.m. (Eastern Time) are processed at
the close of business that same day based on the net asset value of the class of
the portfolios involved  in the  exchange of shares  at the  close of  business.
Requests  received after 4:00 p.m. are processed  the next business day based on
the net  asset value  determined  at the  close of  business  on such  day.  For
additional   information  regarding  responsibility   for  the  authenticity  of
telephoned instructions, see "Redemption of Shares -- By Telephone" above.
    
 
                                       24
<PAGE>
   
TRANSFER OF REGISTRATION
    
 
   
    You may transfer  the registration  of any of  your Fund  shares to  another
person  by writing  to Morgan Stanley  Institutional Fund, Inc.,  P.O. Box 2798,
Boston, Massachusetts 02208-2798.  As in  the case of  redemptions, the  written
request  must  be  received in  good  order  before any  transfer  can  be made.
Transferring the  registration of  shares  may affect  the eligibility  of  your
account  for  a  given  class  of  the  Portfolio's  shares  and  may  result in
involuntary conversion or redemption  of your shares.  See "Purchase of  Shares"
above.
    
 
   
                              VALUATION OF SHARES
    
 
   
    The  net asset  value per  share of a  class of  shares of  the Portfolio is
determined by dividing the total market value of the Portfolio's investments and
other assets attributable to  such class, less  any liabilities attributable  to
such  class, by  the total  number of  outstanding shares  of such  class of the
Portfolio. Net  asset value  is  calculated separately  for  each class  of  the
Portfolio.  Net asset value per share is determined  as of the close of the NYSE
on each day  that the NYSE  is open  for business. Price  information on  listed
securities  is taken from  the exchange where the  security is primarily traded.
Securities listed on a U.S. securities exchange for which market quotations  are
available  are valued at the last quoted sale  price on the day the valuation is
made. Securities listed on a foreign exchange are valued at their closing price.
Unlisted securities and listed securities not  traded on the valuation date  for
which  market quotations  are readily  available are valued  at a  price that is
considered to best represent fair value within a range not exceeding the current
asked price nor  less than  the current  bid price.  The current  bid and  asked
prices are determined based on the bid and asked prices quoted on such valuation
date by reputable brokers.
    
 
    Bonds and other fixed income securities are valued according to the broadest
and  most representative market,  which will ordinarily  be the over-the-counter
market. Net asset value includes interest  on fixed income securities, which  is
accrued  daily.  In addition,  bonds and  other fixed  income securities  may be
valued on the basis of prices provided by a pricing service when such prices are
believed to  reflect  the fair  market  value  of such  securities.  The  prices
provided  by a pricing service are determined without regard to bid or last sale
prices, but take into  account institutional size trading  in similar groups  of
securities  and any developments related  to the specific securities. Securities
not priced in this manner are valued  at the most recently quoted bid price,  or
when securities exchange valuations are used, at the latest quoted sale price on
the  day of valuation. If there is no  such reported sale, the latest quoted bid
price will be used. Securities purchased with remaining maturities of 60 days or
less are valued at amortized cost, if it approximates market value. In the event
that amortized  cost  does  not  approximate  market  value,  market  prices  as
determined above will be used.
 
    The value of other assets and securities for which no quotations are readily
available  (including  restricted  and unlisted  foreign  securities)  and those
securities for which it is inappropriate to determine prices in accordance  with
the  above-stated procedure  are determined  in good  faith at  fair value using
methods determined by the  Board of Directors. For  purposes of calculating  net
asset value per share, all assets and liabilities initially expressed in foreign
currencies will be translated into U.S. dollars at the mean of the bid price and
asked  price of such currencies against the U.S. dollar last quoted by any major
bank.
 
   
    Although the legal rights of Class A  and Class B shares will be  identical,
the  different expenses borne by  each class will result  in different net asset
values   and   dividends   for   the    class.   Dividends   will   differ    by
    
 
                                       25
<PAGE>
   
approximately  the amount of the distribution expense accrual differential among
the classes. The net asset value of Class B shares will generally be lower  than
the  net asset  value of  the Class  A shares  as a  result of  the distribution
expense charged to Class B shares.
    
 
   
                            PERFORMANCE INFORMATION
    
 
   
    The Fund may from time to time advertise total return for each class of  the
Portfolio.  THESE FIGURES ARE BASED ON  HISTORICAL EARNINGS AND ARE NOT INTENDED
TO INDICATE FUTURE PERFORMANCE. The "total return" shows what an investment in a
class of the Portfolio would have earned  over a specified period of time  (such
as one, five or ten years), assuming that all distributions and dividends by the
Portfolio were reinvested in the same class on the reinvestment dates during the
period.  Total return  does not  take into account  any federal  or state income
taxes that may be payable on  dividends and distributions or on redemption.  The
Fund  may  also include  comparative performance  information in  advertising or
marketing the Portfolio's shares. Such performance information may include  data
from  Lipper Analytical  Services, Inc.,  other industry  publications, business
periodicals, rating services and market indices.
    
 
    The performance figures  for Class  B shares  will generally  be lower  than
those  for Class  A shares because  of the  distribution fee charged  to Class B
shares.
 
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
 
   
    All income dividends and capital gains  distributions for a class of  shares
will automatically be reinvested in additional shares of such class at net asset
value,  except that,  upon written  notice to  the Fund  or by  checking off the
appropriate box in the Distribution  Option Section on the Account  Registration
Form,  a shareholder  may elect  to receive  income dividends  and capital gains
distributions in cash. The Portfolio expects to distribute substantially all  of
its  net investment income in the form  of annual dividends. Net realized gains,
if any, after reduction  for any available tax  loss carryforwards will also  be
distributed  annually. Confirmations of the purchase  of shares of the Portfolio
through the  automatic  reinvestment  of  income  dividends  and  capital  gains
distributions  will be  provided, pursuant to  Rule 10b-10  under the Securities
Exchange Act of 1934, as amended, on the next monthly client statement following
such purchase of shares. Consequently, confirmations of such purchases will  not
be  provided at the time  of completion of such  purchases as might otherwise be
required by Rule 10b-10.
    
 
   
    Undistributed net  investment  income is  included  in the  Portfolio's  net
assets  for the purpose of calculating net  asset value per share. Therefore, on
the "ex-dividend" date,  the net  asset value  per share  excludes the  dividend
(i.e.,  is reduced  by the  per share  amount of  the dividend).  Dividends paid
shortly after the purchase of shares by an investor, although in effect a return
of capital, are taxable to shareholders subject to income tax.
    
 
   
    Because of  the  distribution  fee  and  any  other  expenses  that  may  be
attributable  to the  Class B  shares, the  net income  attributable to  and the
dividends payable  on  Class  B  shares  will  be  lower  than  the  net  income
attributable  to and the dividends  payable on Class A  shares. As a result, the
net asset value per share of the classes of the Portfolio will differ at  times.
Expenses of the Portfolio allocated to a particular class of shares thereof will
be borne on a pro rata basis by each outstanding share of that class.
    
 
                                       26
<PAGE>
                                     TAXES
 
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
 
    No  attempt has been made to present  a detailed explanation of the federal,
state, or  local income  tax treatment  of the  Portfolio or  its  shareholders.
Accordingly,  shareholders  are urged  to consult  their tax  advisors regarding
specific questions as to federal, state and local income taxes.
 
    The Portfolio  is  treated as  a  separate  entity for  federal  income  tax
purposes  and is  not combined with  the Fund's other  portfolios. The Portfolio
intends to qualify for the  special tax treatment afforded regulated  investment
companies  under Subchapter M of  the Internal Revenue Code  of 1986, as amended
(the "Code"), so that the  Portfolio will be relieved  of federal income tax  on
that  part of its net investment income and net capital gain that is distributed
to shareholders.
 
   
    The Portfolio distributes  substantially all  of its  net investment  income
(including,  for  this purpose,  net short-term  capital gain)  to shareholders.
Dividends from the Portfolio's net investment income are taxable to shareholders
as ordinary income, whether received in cash or reinvested in additional shares.
Such dividends paid  by the  Portfolio will generally  not qualify  for the  70%
dividends-received  deduction  for  corporate shareholders.  The  Portfolio will
report annually to its shareholders the amount of dividend income qualifying for
such treatment.
    
 
    Distributions of net  capital gains  (i.e., net long-term  capital gains  in
excess  of  net  short-term  capital  losses)  are  taxable  to  shareholders as
long-term capital gains,  regardless of how  long the shareholder  has held  the
Portfolio's  shares. The Portfolio sends reports annually to shareholders of the
federal income tax status of all distributions made during the preceding year.
 
    The  Portfolio   intends  to   make  sufficient   distributions  or   deemed
distributions  of its ordinary income and capital gain net income (the excess of
short-term and long-term  capital gains  over short-term  and long-term  capital
losses), including any available capital loss carryforwards, prior to the end of
each calendar year to avoid liability for federal excise tax.
 
    Dividends  and  other distributions  declared by  the Portfolio  in October,
November or December of any year and payable to shareholders of record on a date
in such month will be deemed to have been paid by the Portfolio and received  by
the  shareholders on December 31  of that year if  the distributions are paid by
the Portfolio at any time during the following January.
 
   
    The sale, exchange  or redemption of  shares may result  in taxable gain  or
loss to the selling, exchanging or redeeming shareholder, depending upon whether
the  fair market value  of the redemption  proceeds exceeds or  is less than the
shareholder's adjusted  basis in  the  redeemed, exchanged  or sold  shares.  If
capital  gain distributions have been made with  respect to shares that are sold
at a loss after being held for six months or less, then the loss is treated as a
long-term capital loss to the extent of the capital gain distributions.
    
 
    The conversion of Class A shares to  Class B shares should not be a  taxable
event to the shareholder.
 
    Shareholders  are urged  to consult with  their tax  advisers concerning the
application of state  and local income  taxes to investments  in the  Portfolio,
which may differ from the federal income tax consequences described above.
 
                                       27
<PAGE>
    Investment  income  received by  the Portfolio  from sources  within foreign
countries may be subject to foreign income taxes withheld at the source. To  the
extent  that the Portfolio is  liable for foreign income  taxes so withheld, the
Portfolio intends to operate so as to meet the requirements of the Code to  pass
through  to the shareholders credit for  foreign income taxes paid. Although the
Portfolio intends to  meet Code  requirements to  pass through  credit for  such
taxes, there can be no assurance that the Portfolio will be able to do so.
 
    THE   TAX  DISCUSSION  SET  FORTH  ABOVE  IS  INCLUDED  HEREIN  FOR  GENERAL
INFORMATION ONLY. PROSPECTIVE  INVESTORS SHOULD CONSULT  THEIR OWN TAX  ADVISERS
WITH RESPECT TO THE TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN THE PORTFOLIO.
 
                             PORTFOLIO TRANSACTIONS
 
    The  Investment  Advisory Agreement  authorizes  the Adviser  to  select the
brokers or  dealers that  will execute  the purchases  and sales  of  investment
securities  for the Portfolio and directs the Adviser to use its best efforts to
obtain the best available price and most favorable execution with respect to all
transactions for  the Portfolio.  The Fund  has authorized  the Adviser  to  pay
higher commissions in recognition of brokerage services which, in the opinion of
the Adviser, are necessary for the achievement of better execution, provided the
Adviser believes this to be in the best interest of the Fund.
 
    Since  shares of the Portfolio are not marketed through intermediary brokers
or dealers, it  is not the  Fund's practice to  allocate brokerage or  principal
business  on the basis of sales of shares  which may be made through such firms.
However, the Adviser  may place portfolio  orders with qualified  broker-dealers
who  recommend the  Fund's portfolios or  who act  as agents in  the purchase of
shares of the Fund's portfolios for their clients.
 
    In purchasing and  selling securities for  the Portfolio, it  is the  Fund's
policy to seek to obtain quality execution at the most favorable prices, through
responsible   broker-dealers.  In   selecting  broker-dealers   to  execute  the
securities transactions for the Portfolio,  consideration will be given to  such
factors  as the price of the security, the  rate of the commission, the size and
difficulty of  the  order,  the  reliability,  integrity,  financial  condition,
general  execution and operational capabilities of competing broker-dealers, and
the brokerage  and  research services  which  they  provide to  the  Fund.  Some
securities  considered for investment  by the Portfolio  may also be appropriate
for other  clients served  by the  Adviser. If  purchase or  sale of  securities
consistent  with the  investment policies  of the Portfolio  and one  or more of
these other clients served  by the Adviser  is considered at  or about the  same
time,  transactions in such securities will be allocated among the Portfolio and
clients in a manner deemed fair and reasonable by the Adviser. Although there is
no specified formula  for allocating such  transactions, the various  allocation
methods used by the Adviser, and the results of such allocations, are subject to
periodic review by the Fund's Board of Directors.
 
    Subject to the overriding objective of obtaining the best possible execution
of  orders, the  Adviser may  allocate a  portion of  each portfolio's brokerage
transactions to Morgan Stanley or broker affiliates of Morgan Stanley. In  order
for  Morgan Stanley or  its affiliates to effect  any portfolio transactions for
the Fund, the commissions, fees or other remuneration received by Morgan Stanley
or such affiliates must be reasonable and fair compared to the commissions, fees
or other  remuneration  paid to  other  brokers in  connection  with  comparable
transactions   involving  similar  securities  being  purchased  or  sold  on  a
securities exchange during a comparable  period of time. Furthermore, the  Board
of Directors of the Fund, including a majority of the
 
                                       28
<PAGE>
Directors  who are not  "interested persons," have  adopted procedures which are
reasonably designed to provide that any commissions, fees or other  remuneration
paid  to Morgan  Stanley or  such affiliates  are consistent  with the foregoing
standard.
 
    Portfolio securities will not be purchased  from, or through, or sold to  or
through,  the Adviser or Morgan Stanley  or any "affiliated persons," as defined
in the Investment Company Act  of 1940, as amended  (the "1940 Act"), of  Morgan
Stanley  when  such entities  are  acting as  principals,  except to  the extent
permitted by law.
 
    Although the  Portfolio will  not invest  for short-term  trading  purposes,
investment securities may be sold from time to time without regard to the length
of  time they have been held. It is anticipated that the annual turnover rate of
the Portfolio will not exceed 100% in normal circumstances.
 
                              GENERAL INFORMATION
 
DESCRIPTION OF COMMON STOCK
 
   
    The Fund  was organized  as a  Maryland corporation  on June  16, 1988.  The
Articles  of Incorporation, as amended and restated, permit the Fund to issue up
to 34 billion shares of common stock,  with $.001 par value per share.  Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number  of shares the  Fund is authorized  to issue without  the approval of the
shareholders of the  Fund. Subject  to the  notice period  to shareholders  with
respect  to shares held by shareholders, the Board of Directors has the power to
designate one or  more classes of  shares of  common stock and  to classify  and
reclassify  any  unissued shares  with respect  to such  classes. The  shares of
common stock of each  portfolio are currently classified  into two classes,  the
Class  A shares and the Class B  shares, except for the International Small Cap,
Money Market and  Municipal Money Market  Portfolios, which only  offer Class  A
shares.
    
 
    The shares of the Portfolio, when issued, will be fully paid, nonassessable,
fully  transferable and redeemable at the option  of the holder. The shares have
no preference  as  to  conversion,  exchange,  dividends,  retirement  or  other
features  and  have  no preemptive  rights.  The  shares of  the  Portfolio have
non-cumulative voting rights, which means that  the holders of more than 50%  of
the  shares voting for the election of Directors can elect 100% of the Directors
if they choose  to do so.  Persons or organizations  owning 25% or  more of  the
outstanding  shares of a portfolio may be presumed to "control" (as that term is
defined in the 1940  Act) that Portfolio.  Under Maryland law,  the Fund is  not
required  to hold an annual meeting of its shareholders unless required to do so
under the 1940 Act.
 
REPORTS TO SHAREHOLDERS
 
    The Fund will send to its  shareholders annual and semi-annual reports;  the
financial  statements  appearing in  annual reports  are audited  by independent
accountants. Monthly unaudited portfolio  data is also  available from the  Fund
upon request.
 
   
    In  addition, the Adviser or its agent, as Transfer Agent, will send to each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
    
 
CUSTODIAN
 
    As of September  1, 1995, domestic  securities and cash  are held by  Chase,
which  replaced U.S.  Trust as  the Fund's domestic  custodian. Chase  is not an
affiliate  of   the   Adviser  or   the   Distributor.  Morgan   Stanley   Trust
 
                                       29
<PAGE>
Company,  Brooklyn,  New York  ("MSTC"),  an affiliate  of  the Adviser  and the
Distributor, acts as the  Fund's custodian for foreign  assets held outside  the
United  States and employs  subcustodians approved by the  Board of Directors of
the  Fund  in  accordance  with  regulations  of  the  Securities  and  Exchange
Commission for the purpose of providing custodial services for such assets. MSTC
may  also hold certain domestic assets for the Fund. For more information on the
custodians, see "General Information --  Custody Arrangements" in the  Statement
of Additional Information.
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
   
    Chase   Global   Funds  Services   Company,   73  Tremont   Street,  Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
    
 
INDEPENDENT ACCOUNTANTS
 
    Price Waterhouse  LLP serves  as independent  accountants for  the Fund  and
audits its annual financial statements.
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       30
<PAGE>
<TABLE>
<CAPTION>
   
   MORGAN STANLEY INSTITUTIONAL FUND, INC.
          ACTIVE COUNTRY ALLOCATION PORTFOLIO
          P.O. BOX 2798, BOSTON, MA 02208-2798

- ---------------------------------------------------------------------------------------------------------------
                           ACCOUNT REGISTRATION FORM
- ---------------------------------------------------------------------------------------------------------------
<S>                        <C>
ACCOUNT INFORMATION        If you need assistance in filling out this form     
Fill in where applicable   for the Morgan Stanley Institutional Fund, please   
                           contact your Morgan Stanley representative or call  
                           us toll free 1-(800)-548-7786. Please print all     
                           items except signature, and mail to the Fund at the
                           address above.

- ---------------------------------------------------------------------------------------------------------------
A)  REGISTRATION
    1. INDIVIDUAL            1. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
                                 First Name           Initial              Last Name
    2. JOINT TENANTS         2. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       (RIGHTS OF                First Name           Initial              Last Name
       SURVIVORSHIP            / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       PRESUMED UNLESS           First Name           Initial              Last Name
       TENANCY IN COMMON 
       IS INDICATED)      
- ---------------------------------------------------------------------------------------------------------------
    3. CORPORATIONS,        3.  / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       TRUSTS AND OTHERS       
       Please call the          / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       Fund for additional
       documents that may       / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       be required to set 
       up account and to 
       authorize transactions.
                                Type of / / INCORPORATED / / UNINCORPORATED / / PARTNERSHIP / / UNIFORM GIFT/TRANSFER TO MINOR 
                                Registration:                 ASSOCIATION                   (ONLY ONE CUSTODIAN AND MINOR PERMITTED)


                                / / TRUST __________________________________     / / OTHER (Specify) ______________________________
- ---------------------------------------------------------------------------------------------------------------
B)  MAILING ADDRESS         Street or P.O. Box / / / / / / / / / / / / / / / / / / / / / / / / / / / /

    Please fill in 
    completely, including   City / / / / / / / / / / / / / State / / / Zip / / / / / /-/ / / / / / / / 
    telephone number(s).
                            Home                                   Business
                            Telephone No./ / / /-/ / / /-/ / / / / Telephone No./ / / /-/ / / /-/ / / /
                            / / United States  / / Resident  / /Non-Resident Alien:
                                Citizen            Alien        Indicate Country of Residence _________
- ---------------------------------------------------------------------------------------------------------------
C)  TAXPAYER                PART 1. Enter your Taxpayer         C) IMPORTANT TAX INFORMATION 
    IDENTIFICATION          Identification Number. For most          You (as a payee) are required by
    NUMBER                  individual taxpayers, this is your     law to provide us (as payer) with
    If the account is in    Social Security Number.                your correct Taxpayer Identification
    more than one name,     TAXPAYER IDENTIFICATION NUMBER         Number. Accounts that have a missing
    CIRCLE THE NAME OF THE    / / / /-/ / / / / / / / /            or incorrect Taxpayer Identification
    PERSON WHOSE TAXPAYER               OR                         Number will be subject to backup
    IDENTIFICATION NUMBER       SOCIAL SECURITY NUMBER             withholding at a 31% rate on dividends,
    IS PROVIDED IN SECTION    / / / /-/ / /-/ / / / /              distributions and other payments.
    A) ABOVE. If no name      PART 2. BACKUP WITHHOLDING           If you have not provided us with
    is circled, the number    / / Check this box if you are        your correct taxpayer identification
    will be considered to be  NOT subject to Backup                number, you may be subject to 
    that of the last name     Withholding under the                a $50 penalty imposed by the Internal
    listed. For Custodian     provisions of Section                Revenue Service.
    account of a minor        3406(a)(1)(C) of the Internal          Backup withholding is not an
    (Uniform Gift/Transfer    Revenue Code.                        additional tax; the tax liability of
    to Minor Act), give the                                        persons subject to backup withholding
    Social Security Number                                         will be reduced by the amount of tax
    of the minor.                                                  withheld. If withholding results in
                                                                   an overpayment of taxes, a refund 
                                                                   may be obtained. You may be notified
                                                                   that you are subject to backup 
                                                                   withholding under Section 3406(a)(1)(C)
                                                                   of the Internal Revenue Code because you
                                                                   have underreported interest or dividends
                                                                   or you were required to but failed to
                                                                   file a return which would have included a
                                                                   reportable interest or dividend payment. IF
                                                                   YOU HAVE NOT BEEN SO NOTIFIED, CHECK THE
                                                                   BOX IN PART 2 AT LEFT.

    
- ---------------------------------------------------------------------------------------------------------------
   
D)  PORTFOLIO AND          For Purchase of the following Portfolio(s):     
    CLASS SELECTION        Active Country Allocation Portfolio          / / Class A Shares $____ / / Class B Shares $____
    (Class A shares
    minimum $500,000
    for each Portfolio                                                      Total Initial Investment $_____________
    and Class B shares
    minimum $100,000 for
    each Portfolio).
    Please indicate
    class and amount.
    
- ---------------------------------------------------------------------------------------------------------------
   
E)  METHOD OF   Payment by:
    INVESTMENT  / / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND, INC.--ACTIVE COUNTRY ALLOCATION PORTFOLIO)
    Please
    indicate
    manner of   / / Exchange $____________ From________________       / / / / / / / / / / /-/ /
    payment.                                Name of Portfolio              Account No.

               / / Account previously established by: 

               / / Phone exchange / / Wire on___________________       / / / / / / / / / / / /-/ /
                                                          Date             Account No.            (Check
                                                                 (Previously assigned by the Fund) Digit)
    
 
<PAGE>

- ---------------------------------------------------------------------------------------------------------------

F)  DISTRIBUTION                                       Income dividends and capital gains distributions (if any) will
    OPTION                                             be reinvested in additional shares unless either box below is
                                                       checked.

                                                       / / Income dividends to be paid in cash, capital
                                                           gains distributions (if any) in shares.

                                                      / /  Income dividends and capital gains distributions
                                                           (if any) to be paid in cash.

- ---------------------------------------------------------------------------------------------------------------


G)  TELEPHONE                    / / I/we hereby authorize the Fund and its      ______________________   ________________
    REDEMPTION                       agents to honor any telephone requests      Name of COMMERCIAL Bank  Bank Account No.
    Please select at time of         to wire redemption proceeds to the            (Not Savings Bank)
    initial application if you       commercial bank indicated at rightand/or 
    wish to redeem shares by         mail redemption proceeds to the name and                             ________________
    telephone. A SIGNATURE           address in which my/our fund account is                                 Bank ABA No.
    GUARANTEE IS REQUIRED IF         registered if such requests are believed 
    BANK ACCOUNT IS NOT              to be authentic.                           _________________________________________________
    REGISTERED IDENTICALLY TO    The Fund and the Fund's Transfer Agent will    Name(s) in which your BANK Account is Established
    YOUR FUND ACCOUNT.           employ reasonable procedures to confirm that
                                 instructions communicated by telephone are     _________________________________________________
    TELEPHONE REQUESTS FOR       genuine. These procedures include requiring                 Bank's Street Address
    REDEMPTIONS WILL NOT BE      the investor to provide certain personal
    HONORED UNLESS THE BOX IS    identification information at the time an      _________________________________________________
    CHECKED.                     account is opened and prior to effecting each  City                    State                Zip
                                 transaction requested by telephone. In addition,
                                 all telephone transaction requests will be recorded
                                 and investors may be required to provide additional
                                 telecopied written instructions of transaction
                                 requests. Neither the Fund nor the Transfer Agent will
                                 be responsible for any loss, liability, cost or expense
                                 for following instructions received by telephone that
                                 it reasonably believes to be genuine.


- ---------------------------------------------------------------------------------------------------------------

H)  INTERESTED PARTY
    OPTION
    In addition to the account   _________________________________________________________________
    statement sent to my/our                                 Name
    registered address, I/we     _________________________________________________________________
    hereby authorize the fund    
    to mail duplicate            _________________________________________________________________
    statements to the name and                              Address
    address provided at right.
                                 _________________________________________________________________
                                  City                      State                     Zip Code

- ---------------------------------------------------------------------------------------------------------------

I)  DEALER 
    INFORMATION                  _______________________  _______________________________  ___________
                                 Representative Name          Representative No.             Branch No.

- ---------------------------------------------------------------------------------------------------------------

J)  SIGNATURE OF        The undersigned certify(ies)  that I/we  have full  authority and  legal
    ALL HOLDERS         capacity  to purchase and redeem shares of the Fund and affirm that I/we
    AND TAXPAYER        have received a current Prospectus  of the Morgan Stanley  Institutional
    CERTIFICATION       Fund,  Inc. and agree to  be bound by its  terms. UNDER THE PENALTIES OF
    Sign Here >         PERJURY, I/WE CERTIFY THAT THE INFORMATION PROVIDED IN SECTION C)
                        ABOVE IS TRUE, CORRECT AND COMPLETE.

                        (X)                                 (X)
                        __________________________________  ______________________________________
                        Signature                Date       Signature                  Date

- ---------------------------------------------------------------------------------------------------------------


</TABLE>


<PAGE>
                 (This page has been left blank intentionally.)
<PAGE>
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
 
  NO  DEALER, SALES  REPRESENTATIVE OR ANY  OTHER PERSON HAS  BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE  CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS  HAVING BEEN AUTHORIZED BY THE FUND  OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF  THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION  TO
ANY  PERSON TO WHOM  IT IS UNLAWFUL TO  MAKE SUCH OFFER  OR SOLICITATION IN SUCH
JURISDICTION.
 
                           --------------------------
 
                               TABLE OF CONTENTS
 
   
<TABLE>
<S>                                                 <C>
                                                    PAGE
                                                    ----
Fund Expenses.....................................    2
Financial Highlights..............................    4
Prospectus Summary................................    6
Investment Objective and Policies.................   10
Additional Investment Information.................   12
Investment Limitations............................   15
Management of the Fund............................   15
Purchase of Shares................................   18
Redemption of Shares..............................   22
Shareholder Services..............................   24
Valuation of Shares...............................   25
Performance Information...........................   26
Dividends and Capital Gains Distributions.........   26
Taxes.............................................   27
Portfolio Transactions............................   28
General Information...............................   29
Account Registration Form
</TABLE>
    
 
                      ACTIVE COUNTRY ALLOCATION PORTFOLIO
 
                               A PORTFOLIO OF THE
 
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
 
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
 
- ---------------------------------
- ---------------------------------
- ---------------------------------
- ---------------------------------
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
     ----------------------------------------------------------------------
 
                                 GOLD PORTFOLIO
 
                               A PORTFOLIO OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
 
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
                                ----------------
 
   
    Morgan  Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company, or mutual fund, which offers redeemable shares in
a   series   of   diversified   and   non-diversified   investment    portfolios
("portfolios").   The  Fund   currently  consists   of  twenty-eight  portfolios
representing a  broad range  of  investment choices.  The  Fund is  designed  to
provide clients with attractive alternatives for meeting their investment needs.
This  prospectus (the  "Prospectus") pertains  to the  Class A  and the  Class B
shares of  the  Gold  Portfolio  (the "Portfolio").  On  January  2,  1996,  the
Portfolio began offering two classes of shares, the Class A shares and the Class
B  shares, except for the Money Market, Municipal Money Market and International
Small Cap  Portfolios  which  only offer  Class  A  shares. All  shares  of  the
Portfolio  owned prior to  January 2, 1996  were redesignated Class  A shares on
January 2,  1996. The  Class  A and  Class B  shares  currently offered  by  the
Portfolio  have  different minimum  investment  requirements and  fund expenses.
Shares of  the  portfolios are  offered  with no  sales  charge or  exchange  or
redemption fee (with the exception of the International Small Cap Portfolio).
    
 
    The  GOLD  PORTFOLIO  seeks  to provide  long-term  capital  appreciation by
investing primarily in  the equity  securities of foreign  and domestic  issuers
engaged in gold-related activities.
 
    INVESTORS  SHOULD NOTE THAT THE PORTFOLIO MAY  INVEST UP TO 10% OF ITS TOTAL
ASSETS IN RESTRICTED SECURITIES, AND IT MAY INVEST UP TO 20% OF ITS TOTAL ASSETS
IN  RESTRICTED  SECURITIES  THAT  ARE  RULE  144A  SECURITIES.  SEE  "ADDITIONAL
INVESTMENT INFORMATION -- NON-PUBLICLY TRADED SECURITIES, PRIVATE PLACEMENTS AND
RESTRICTED  SECURITIES." INVESTMENTS  IN EXCESS OF  5% OF  THE PORTFOLIO'S TOTAL
ASSETS MAY BE CONSIDERED A SPECULATIVE  ACTIVITY, MAY INVOLVE GREATER RISK,  AND
MAY INCREASE THE PORTFOLIO'S EXPENSES.
 
    The  Fund is designed  to meet the investment  needs of discerning investors
who place a premium on quality  and personal service. With Morgan Stanley  Asset
Management   Inc.  as   Adviser  and   Administrator  (the   "Adviser"  and  the
"Administrator"), and with Morgan Stanley & Co. Incorporated ("Morgan  Stanley")
as Distributor, the Fund makes available to institutional investors and high net
worth  individual  investors  a  series of  portfolios  which  benefit  from the
investment expertise and commitment to excellence associated with Morgan Stanley
and its affiliates.
 
   
    This Prospectus is designed to set forth concisely the information about the
Fund that a prospective investor should  know before investing and it should  be
retained  for future reference. The Fund  offers additional portfolios which are
described in other prospectuses and  under "Prospectus Summary" below. The  Fund
currently  offers the following portfolios:  (i) GLOBAL AND INTERNATIONAL EQUITY
- -- Active Country Allocation, Asian  Equity, Emerging Markets, European  Equity,
Global  Equity, Gold, International  Equity, International Magnum, International
Small Cap, Japanese Equity  and Latin American Portfolios;  (ii) U.S. EQUITY  --
Aggressive  Equity, Emerging  Growth, Equity  Growth, MicroCap,  Small Cap Value
Equity, U.S. Real  Estate and Value  Equity Portfolios; (iii)  EQUITY AND  FIXED
INCOME  -- Balanced Portfolio; (iv) FIXED INCOME -- Emerging Markets Debt, Fixed
Income,  Global  Fixed  Income,  High  Yield,  Mortgage-Backed  Securities   and
Municipal  Bond Portfolios; and  (v) MONEY MARKET --  Money Market and Municipal
Money Market Portfolios. Additional information about the Fund is contained in a
"Statement of Additional Information," dated May 1, 1996, which is  incorporated
herein   by  reference.  The   Statement  of  Additional   Information  and  the
prospectuses pertaining to the other portfolios  of the Fund are available  upon
request  and without charge  by writing or  calling the Fund  at the address and
telephone number set forth above.
    
 
   
THESE SECURITIES HAVE NOT BEEN APPROVED  OR DISAPPROVED BY THE SECURITIES  AND
  EXCHANGE  COMMISSION  OR ANY  STATE  SECURITIES COMMISSION,  NOR  HAS THE
     SECURITIES AND EXCHANGE COMMISSION OR ANY STATE SECURITIES COMMISSION
       PASSED  UPON  THE  ACCURACY   OR  ADEQUACY  OF  THIS   PROSPECTUS.
        ANY  REPRESENTATION  TO  THE  CONTRARY  IS  A  CRIMINAL OFFENSE.
    
 
   
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1996.
    
<PAGE>
                                 FUND EXPENSES
 
    The  following table illustrates the expenses and fees that a shareholder of
the Gold Portfolio will incur:
   
<TABLE>
<CAPTION>
SHAREHOLDER TRANSACTION EXPENSES
- --------------------------------------------------------------------------------------------
<S>                                                                                           <C>
Maximum Sales Load Imposed on Purchases
  Class A...................................................................................       None
  Class B...................................................................................       None
Maximum Sales Load Imposed on Reinvested Dividends
  Class A...................................................................................       None
  Class B...................................................................................       None
Deferred Sales Load
  Class A...................................................................................       None
  Class B...................................................................................       None
Redemption Fees
  Class A...................................................................................       None
  Class B...................................................................................       None
Exchange Fees
  Class A...................................................................................       None
  Class B...................................................................................       None
 
<CAPTION>
 
ANNUAL FUND OPERATING EXPENSES
- --------------------------------------------------------------------------------------------
<S>                                                                                           <C>
 (AS A PERCENTAGE OF AVERAGE NET ASSETS)
Management Fee (Net of Fee Waiver)*
  Class A...................................................................................      0.49%
  Class B...................................................................................      0.49%
12b-1 Fees
  Class A...................................................................................       None
  Class B...................................................................................      0.25%
Other Expenses
  Class A...................................................................................      0.76%
  Class B...................................................................................      0.76%
                                                                                              ---------
  Total Operating Expenses (Net of Fee Waivers)*
  Class A...................................................................................      1.25%
  Class B...................................................................................      1.50%
                                                                                              ---------
                                                                                              ---------
</TABLE>
    
 
- ------------------------------
   
*The Adviser has  agreed to waive  its management fees  and/or to reimburse  the
 Portfolio,  if necessary, if such fees would cause the Portfolio's total annual
 operating expenses, as a percentage of average daily net assets, to exceed  the
 percentages set forth in the table above. Absent the fee waiver, the management
 fee  would be  1.00%. Absent the  fee waiver and/or  expense reimbursement, the
 Portfolio's total operating expenses  would be 1.76% of  the average daily  net
 assets  of the Class A shares and 2.01%  of the average daily net assets of the
 Class B shares. As a result of this reduction, the Management Fee stated  above
 is  lower than the contractual  fee stated under "Management  of the Fund." The
 Adviser reserves the right to terminate  any of its fee waivers and/or  expense
 reimbursements  at any time in its  sole discretion. For further information on
 Fund expenses, see "Management of the Fund."
    
 
   
    The purpose of the  table above is to  assist the investor in  understanding
the  various expenses that  an investor in  the Portfolio will  bear directly or
indirectly.  The  Class  A  expenses  and  fees  for  the  Portfolio  are  based
    
 
                                       2
<PAGE>
   
on  actual figures  for the  fiscal year  ended December  31, 1995.  The Class B
expenses and fees for  the Portfolio are based  on estimates, assuming that  the
average  daily  net  assets of  the  Class B  shares  of the  Portfolio  will be
$50,000,000. "Other Expenses"  include Board  of Directors'  fees and  expenses,
amortization  of organizational costs, filing  fees, professional fees and costs
for shareholder reports. Due to the  continuous nature of Rule 12b-1 fees,  long
term  Class  B shareholders  may pay  more  than the  equivalent of  the maximum
front-end sales charges otherwise permitted by the Rules of Fair Practice of the
National Association of Securities Dealers, Inc. ("NASD").
    
 
    The following  example illustrates  the expenses  that you  would pay  on  a
$1,000  investment assuming (1) a 5% annual rate of return and (2) redemption at
the end of each time period. As noted in the table above, the Portfolio  charges
no redemption fees of any kind. The example is based on total operating expenses
of the Portfolio after fee waivers.
 
<TABLE>
<CAPTION>
                                                                       1 YEAR       3 YEARS      5 YEARS     10 YEARS
                                                                     -----------  -----------  -----------  -----------
<S>                                                                  <C>          <C>          <C>          <C>
Gold Portfolio
  Class A..........................................................   $      13    $      40    $      69    $     151
  Class B..........................................................          15           47           82          179
</TABLE>
 
    THIS  EXAMPLE SHOULD  NOT BE CONSIDERED  A REPRESENTATION OF  PAST OR FUTURE
EXPENSES OR  PERFORMANCE. ACTUAL  EXPENSES MAY  BE GREATER  OR LESS  THAN  THOSE
SHOWN.
 
    The  Fund intends  to comply  with all  state laws  that restrict investment
company expenses. Currently, the  most restrictive state  law requires that  the
aggregate  annual expenses  of an  investment company  shall not  exceed two and
one-half percent (2 1/2%) of  the first $30 million  of average net assets,  two
percent (2%) of the next $70 million of average net assets, and one and one-half
percent (1 1/2%) of the remaining net assets of such investment company.
 
    The  Adviser has agreed to a reduction in  the amounts payable to it, and to
reimburse the Portfolio,  if necessary, if  in any  fiscal year the  sum of  the
Portfolio's  expenses  exceeds the  limit set  by applicable  state law.  If the
Adviser is  required  to so  reduce  its fee  or  reimburse the  Portfolio,  the
Sub-Adviser  has agreed to  a proportionate waiver  of its fee  payable from the
Adviser or reimbursement of expenses.
 
                                       3
<PAGE>
                              FINANCIAL HIGHLIGHTS
 
   
    The following table provides financial highlights for the Class A shares  of
the  Portfolio  for  each  of  the  periods  described.  The  audited  financial
highlights for the Class A  shares for the fiscal  year ended December 31,  1995
are  part of the Fund's financial statements which appear in the Fund's December
31, 1995 Annual  Report to  Shareholders and which  are included  in the  Fund's
Statement  of Additional  Information. The Portfolio's  financial highlights for
each of the periods presented have  been audited by Price Waterhouse LLP,  whose
unqualified  report  thereon is  also included  in  the Statement  of Additional
Information. Additional  performance  information  for the  Class  A  shares  is
included  in the Annual  Report. The Annual Report  and the financial statements
therein, along with the Statement of Additional Information, are available at no
cost from the Fund at the address  and telephone number noted on the cover  page
of  this Prospectus. Financial highlights are not  available for the new Class B
shares since  they were  not offered  as  of December  31, 1995.  The  following
information  should be  read in  conjunction with  the financial  statements and
notes thereto.
    
 
                                       4
<PAGE>
                                 GOLD PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                    PERIOD FROM FEBRUARY
                                                         1, 1994* TO           YEAR ENDED
                                                      DECEMBER 31, 1994     DECEMBER 31, 1995
                                                    ---------------------   -----------------
<S>                                                 <C>                     <C>
NET ASSET VALUE, BEGINNING OF PERIOD..............         $ 10.00               $ 9.13
                                                           -------               ------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income/(Loss) (1)................            0.03                (0.07)
  Net Realized and Unrealized Gain/(Loss) on
   Investments....................................           (0.88)                1.22
                                                           -------               ------
    Total from Investment Operations..............           (0.85)                1.15
                                                           -------               ------
DISTRIBUTIONS
  Net Investment Income...........................           (0.02)               (0.01)
  Net Realized Gain...............................              --                (1.72)
                                                           -------               ------
    Total Distributions...........................           (0.02)               (1.73)
                                                           -------               ------
NET ASSET VALUE, END OF PERIOD....................         $  9.13               $ 8.55
                                                           -------               ------
                                                           -------               ------
TOTAL RETURN......................................           (8.49)%              13.21%
                                                           -------               ------
                                                           -------               ------
RATIO AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands).............         $30,243               $7,409
Ratio of Expenses to Average Net Assets (1)(2)....            1.25%**              1.25%
Ratio of Net Investment Income/(Loss) to Average
 Net Assets (1)(2)................................            0.41%**             (0.31)%
Portfolio Turnover Rate...........................              56%                  47%
- ------------------------
(1) Effect of voluntary expense limitation during
 the period:
     Per share benefit to net investment income...         $  0.04               $ 0.11
   Ratios before expense limitation:
     Expenses to Average Net Assets...............            1.72%**              1.76%
     Net Investment Loss to Average Net Assets....           (0.06)%**            (0.82)%
</TABLE>
    
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to receive an investment advisory fee calculated at an annual rate of  1.00%
    of  the average daily net assets of the Portfolio. The Adviser has agreed to
    waive a portion of  this fee and/or reimburse  expenses of the Portfolio  to
    the  extent that the total operating  expenses of the Portfolio exceed 1.25%
    of the average  daily net  assets of  the Class A  shares and  1.50% of  the
    average  daily  net assets  of  the Class  B  shares. In  the  periods ended
    December 31, 1994 and  December 31, 1995, the  Adviser waived advisory  fees
    and/or  reimbursed expenses totaling $55,000  and $55,000, respectively, for
    the Portfolio.
    
 
 * Commencement of Operations.
 
 ** Annualized.
 
                                       5
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
 
   
    The  Fund  consists  of  twenty-eight  portfolios,  offering   institutional
investors  and high net  worth individual investors a  broad range of investment
choices coupled with the advantages of a no-load mutual fund with Morgan Stanley
and its affiliates providing customized  services as Adviser, Administrator  and
Distributor.  Each portfolio offers Class A shares and, except the International
Small Cap, Money Market and Municipal Money Market Portfolios, also offers Class
B shares. Each portfolio has its own investment objective and policies  designed
to meet its specific goals. The investment objective of the Gold Portfolio is as
follows:
    
 
    - The  GOLD  PORTFOLIO seeks  to provide  long-term capital  appreciation by
      investing primarily  in  the equity  securities  of foreign  and  domestic
      issuers  engaged in gold-related  activities. The other  portfolios of the
      Fund are described in  other prospectuses which may  be obtained from  the
      Fund  at the address and telephone number  noted on the cover page of this
      Prospectus. The objectives of these other portfolios are listed below:
 
    GLOBAL AND INTERNATIONAL EQUITY:
 
   
    - The  ACTIVE   COUNTRY  ALLOCATION   PORTFOLIO  seeks   long-term   capital
      appreciation by investing in accordance with country weightings determined
      by  the Adviser  in equity  securities of  non-U.S. issuers  which, in the
      aggregate, replicate broad country indices.
    
 
   
    - The  ASIAN  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
      investing primarily in equity securities of Asian issuers.
    
 
   
    - The CHINA GROWTH PORTFOLIO seeks to provide long-term capital appreciation
      by investing primarily in the equity securities of issuers in The People's
      Republic of China, Hong Kong and Taiwan.
    
 
   
    - The  EMERGING MARKETS  PORTFOLIO seeks  long-term capital  appreciation by
      investing primarily in equity securities of emerging country issuers.
    
 
   
    - The EUROPEAN  EQUITY PORTFOLIO  seeks  long-term capital  appreciation  by
      investing primarily in equity securities of European issuers.
    
 
   
    - The  GLOBAL  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation by
      investing primarily in equity securities of issuers throughout the  world,
      including U.S. issuers.
    
 
   
    - The INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of non-U.S. issuers.
    
 
   
    - The INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of non-U.S. issuers in accordance
      with  EAFE  country (as  defined  in "Investment  Objective  and Policies"
      below) weightings determined by the Adviser.
    
 
   
    - The INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital appreciation
      by investing  primarily  in equity  securities  of non-U.S.  issuers  with
      equity market capitalizations of less than $1 billion.
    
 
                                       6
<PAGE>
    - The  JAPANESE  EQUITY PORTFOLIO  seeks  long-term capital  appreciation by
      investing primarily in equity securities of Japanese issuers.
 
    - The LATIN  AMERICAN  PORTFOLIO  seeks long-term  capital  appreciation  by
      investing  primarily in  equity securities  of Latin  American issuers and
      debt securities  issued or  guaranteed by  Latin American  governments  or
      governmental entities.
 
    U.S. EQUITY:
 
   
    - The  AGGRESSIVE EQUITY  PORTFOLIO seeks capital  appreciation by investing
      primarily in corporate equity and equity-linked securities.
    
 
   
    - The EMERGING  GROWTH PORTFOLIO  seeks  long-term capital  appreciation  by
      investing    primarily   in    growth-oriented   equity    securities   of
      small-to-medium sized corporations.
    
 
   
    - The EQUITY  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation  by
      investing  in  growth-oriented  equity  securities  of  medium  and  large
      capitalization companies.
    
 
   
    - The MICROCAP PORTFOLIO seeks  long-term capital appreciation by  investing
      primarily in growth-oriented equity securities of small corporations.
    
 
   
    - The  SMALL CAP VALUE EQUITY PORTFOLIO seeks high long-term total return by
      investing  in  undervalued  equity  securities  of  small-to-medium  sized
      companies.
    
 
   
    - The  U.S. REAL  ESTATE PORTFOLIO  seeks to  provide above  average current
      income and long-term capital appreciation by investing primarily in equity
      securities of companies in the  U.S. real estate industry, including  real
      estate investment trusts.
    
 
   
    - The  VALUE EQUITY PORTFOLIO seeks high total return by investing in equity
      securities which the Adviser  believes to be  undervalued relative to  the
      stock market in general at the time of purchase.
    
 
   
    EQUITY AND FIXED INCOME:
    
 
   
    - The BALANCED PORTFOLIO seeks high total return while preserving capital by
      investing  in  a combination  of undervalued  equity securities  and fixed
      income securities.
    
 
   
    FIXED INCOME:
    
 
   
    - The EMERGING MARKETS DEBT PORTFOLIO  seeks high total return by  investing
      primarily   in  debt  securities  of  government,  government-related  and
      corporate issuers in emerging countries.
    
 
   
    - The FIXED INCOME PORTFOLIO seeks to produce a high total return consistent
      with the preservation of capital  by investing in a diversified  portfolio
      of fixed income securities.
    
 
   
    - The GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real rate
      of return while preserving capital by investing in fixed income securities
      of issuers throughout the world, including U.S. issuers.
    
 
   
    - The  HIGH YIELD PORTFOLIO seeks to maximize total return by investing in a
      diversified portfolio of high yield  fixed income securities that offer  a
      yield  above  that generally  available on  debt  securities in  the three
      highest rating categories of the recognized rating services.
    
 
                                       7
<PAGE>
    - The MORTGAGE-BACKED SECURITIES PORTFOLIO seeks to produce as high a  level
      of  current income  as is consistent  with the preservation  of capital by
      investing primarily  in  a  variety  of  investment-grade  mortgage-backed
      securities.
 
    - The  MUNICIPAL BOND  PORTFOLIO seeks  to produce  a high  level of current
      income  consistent  with  preservation  of  principal  through  investment
      primarily  in municipal obligations, the interest  on which is exempt from
      federal income tax.
 
    MONEY MARKET:
 
    - The MONEY MARKET PORTFOLIO seeks  to maximize current income and  preserve
      capital  while maintaining high  levels of liquidity  through investing in
      high quality money  market instruments  with remaining  maturities of  one
      year or less.
 
    - The  MUNICIPAL MONEY MARKET PORTFOLIO seeks to maximize current tax-exempt
      income and preserve  capital while  maintaining high  levels of  liquidity
      through  investing in high quality money market instruments with remaining
      maturities of one year or less which are exempt from federal income tax.
 
INVESTMENT MANAGEMENT
 
   
    Morgan Stanley Asset Management  Inc., a wholly  owned subsidiary of  Morgan
Stanley  Group  Inc.,  which,  together  with  its  affiliated  asset management
companies, at March  31, 1996 had  approximately $57.4 billion  in assets  under
management  as  an  investment  manager  or  as  a  fiduciary  adviser,  acts as
investment adviser  to the  Fund and  each of  its portfolios.  Sun Valley  Gold
Company  (the "Sub-Adviser"),  which at  March 31,  1996 had  approximately $192
million in assets under  management, acts as sub-adviser  to the Portfolio.  See
"Management  of the Fund -- Investment  Adviser and Sub-Adviser" and "Management
of the Fund -- Administrator."
    
 
HOW TO INVEST
 
   
    Class A shares  of the Portfolio  are offered directly  to investors at  net
asset  value with no  sales commission or  12b-1 charges. Class  B shares of the
Portfolio are offered at net  asset value with no  sales commission, but with  a
12b-1  fee, which  is accrued daily  and paid  quarterly, equal to  0.25% of the
Class B shares' average daily net assets on an annualized basis. Share purchases
may be  made  by  sending  investments  directly to  the  Fund  or  through  the
Distributor.  Shares  in a  Portfolio account  opened prior  to January  2, 1996
(each, a "Pre-1996 Account") were designated Class A shares on January 2,  1996.
For  a Portfolio account opened  on or after January  2, 1996 (a "New Account"),
the minimum initial investment is $500,000  for Class A shares and $100,000  for
Class B shares. Certain exceptions to the foregoing minimums apply to (1) shares
in  a Pre-1996  Account with a  value of  $100,000 or more  on March  1, 1996 (a
"Grandfathered Class A Account"); (2) Portfolio accounts held by officers of the
Adviser and  its  affiliates;  and  (3) certain  advisory  or  asset  allocation
accounts,  such as Total Funds Management accounts, managed by Morgan Stanley or
its affiliates, including the Adviser ("Managed Accounts"). The Adviser reserves
the right in its sole  discretion to determine which  of such advisory or  asset
allocation accounts shall be Managed Accounts. For information regarding Managed
Accounts,  please contact your Morgan Stanley account representative or the Fund
at the telephone number provided  on the cover of  this Prospectus. Shares in  a
Pre-1996  Account  with  a value  of  less than  $100,000  on March  1,  1996 (a
"Grandfathered Class B Account") converted to  Class B shares on March 1,  1996.
The minimum investment levels may be waived at the discretion of the Adviser for
(i)  certain employees  and customers  of Morgan  Stanley or  its affiliates and
certain  trust  departments,  brokers,  dealers,  agents,  financial   planners,
financial services firms, or investment
    
 
                                       8
<PAGE>
   
advisers  that  have  entered  into  an agreement  with  Morgan  Stanley  or its
affiliates; and (ii) retirement and deferred compensation plans and trusts  used
to  fund such  plans, including,  but not limited  to, those  defined in Section
401(a), 403(b) or  457 of the  Internal Revenue  Code of 1986,  as amended,  and
"rabbi trusts". See "Purchase of Shares -- Minimum Investment and Account Sizes;
Conversion from Class A to Class B Shares."
    
 
   
    The  minimum subsequent investment for a Portfolio account is $1,000 (except
for automatic  reinvestment of  dividends and  capital gains  distributions  for
which  there  is no  minimum). Such  subsequent investments  will be  applied to
purchase additional  shares  in  the same  class  held  by a  shareholder  in  a
Portfolio account. See "Purchase of Shares -- Additional Investments."
    
 
HOW TO REDEEM
 
   
    Class  A shares or  Class B shares of  the Portfolio may  be redeemed at any
time, without cost, at the net asset value per share of shares of the applicable
class next determined after  receipt of the  redemption request. The  redemption
price may be more or less than the purchase price. Certain redemptions may cause
involuntary  redemption or automatic conversion. Class  A or Class B shares held
in  New  Accounts   are  subject  to   involuntary  redemption  if   shareholder
redemption(s)  of such  shares reduces  the value of  such account  to less than
$100,000 for a continuous 60-day  period. Involuntary redemption does not  apply
to  Managed Accounts, Grandfathered  Class A Accounts  and Grandfathered Class B
Accounts, regardless of  the value of  such accounts.  Class A shares  in a  New
Account  will convert  to Class  B shares  if shareholder  redemption(s) of such
shares reduces the value of such account to less than $500,000 for a  continuous
60-day period. Class B shares in a New Account will convert to Class A shares if
shareholder purchases of additional Class B shares or market activity causes the
value  of the Class B shares in the New Account to increase to $500,000 or more.
See "Purchase of Shares -- Minimum  Account Sizes and Involuntary Redemption  of
Shares" and "Redemption of Shares."
    
RISK FACTORS
 
    The   investment  policies  of  the   Portfolio  entail  certain  risks  and
considerations of which an investor should be aware. The Portfolio's investments
may be subject to greater risk and  market fluctuation than a fund that  invests
in   securities  representing  a  broader   range  of  investment  alternatives.
Historically, stock  prices of  companies  involved in  precious  metals-related
industries  have been volatile.  In addition, prices of  gold and other precious
metals and minerals  may fluctuate  sharply over short  periods of  time due  to
various  world-wide economic, financial and political factors. The Portfolio may
also invest in securities of foreign issuers which are subject to certain  risks
not typically associated with domestic securities. See "Investment Objective and
Policies."  In addition, the Portfolio may invest in repurchase agreements, lend
its portfolio securities  and purchase  securities on a  when-issued basis.  The
Portfolio  may invest  in forward foreign  currency exchange  contracts to hedge
currency  risk  associated  with  investment  in  non-U.S.  dollar   denominated
securities and may purchase and sell options and enter into futures transactions
and options thereon for hedging purposes. The Portfolio may invest in short-term
or  medium-term debt securities  or hold cash or  cash equivalents for temporary
defensive purposes. The Portfolio may also invest in securities that are neither
listed on  a  stock  exchange nor  traded  over-the-counter,  including  private
placement  securities. The  Portfolio may  also invest  indirectly in securities
through sponsored or  unsponsored American  Depositary Receipts.  Each of  these
investment   strategies  involves  specific  risks  which  are  described  under
"Investment Objectives  and Policies"  and "Additional  Investment  Information"
herein  and  under  "Investment  Objective and  Policies"  in  the  Statement of
Additional Information.
 
                                       9
<PAGE>
                       INVESTMENT OBJECTIVE AND POLICIES
 
    The  investment  objective  of  the  Gold  Portfolio  is  long-term  capital
appreciation.  The  production  of  any current  income  is  incidental  to this
objective. The Portfolio seeks to  achieve its objective by investing  primarily
in  the equity securities of foreign and domestic issuers principally engaged in
gold-related  activities.  There  can  be  no  assurance  that  the  Portfolio's
investment objective will be achieved. The Portfolio's investment objective is a
fundamental  policy which may not be changed  without the approval of a majority
of the  Portfolio's outstanding  voting securities.  Because the  securities  in
which  the  Portfolio  invests  may  involve  risks  not  associated  with  more
traditional investments, an investment in  the Portfolio, by itself, should  not
be considered a balanced investment program.
 
   
    Under  normal circumstances, the  Portfolio will invest at  least 70% of its
total assets  in  equity securities  of  companies principally  engaged  in  the
exploration,  mining, fabrication,  processing, distribution or  trading of gold
(or, to a lesser degree, silver, platinum or other precious metals or  minerals)
or  the financing,  managing, controlling or  operating of  companies engaged in
such activities. (Such activities and the activities of such related  financing,
managing,   controlling  or  operating  companies  are  referred  to  herein  as
"gold-related" or "precious-metals-related" activities.)  For these purposes,  a
company  will be considered to  be principally engaged in  such activities if it
derives more than 50% of  its income, or devotes 50%  or more of its assets,  to
such activities. With respect to the Portfolio, equity securities include common
and  preferred  stocks,  convertible  securities,  and  rights  and  warrants to
purchase common stocks.  The Portfolio will  invest more than  25% of its  total
assets  in  securities  of companies  in  the  group of  industries  involved in
gold-related or precious-metals-related activities, as described above, and  may
invest  more than 25% of its total assets in one or more of the industries, such
as mining, that  are a part  of such  group of industries,  as described  above.
Potential  investors in the Portfolio should  consider the possibly greater risk
arising from  the  concentration of  the  Portfolio's investments  in  one  such
industry or the group of industries.
    
 
    Because most of the world's gold production is outside of the United States,
the  Portfolio expects that a significant portion  of its assets may be invested
in  securities  of  foreign  issuers.  The  percentage  of  assets  invested  in
particular countries or regions will change from time to time in accordance with
the  judgment of Morgan  Stanley Asset Management, Inc.  (the "Adviser") and Sun
Valley Gold Company (the "Sub-Adviser",  and collectively with the Adviser,  the
"Advisers"),  which may  be based on,  among other things,  consideration of the
political stability and economic  outlook of these countries  or regions. It  is
currently  anticipated, however, that the Portfolio's assets will be principally
invested in the  equity securities of  companies located in  the United  States,
Canada  and  Australia, and  the Portfolio's  assets may  be invested  in equity
securities of companies located in South Africa.
 
    The Portfolio expects to invest in foreign securities by buying the  foreign
securities  themselves, but the Portfolio may also invest in American Depositary
Receipts ("ADRs"), European Depositary  Receipts ("EDRs") or similar  securities
that  are  convertible  into securities  of  foreign issuers  and  that evidence
ownership of the underlying foreign security  when the Advisers believe that  it
is  in the best interest of the  Portfolio to do so. ADRs are dollar-denominated
receipts that are  generally issued  by domestic  banks or  trust companies  and
which  represent the deposit with  the bank or trust company  of a security of a
foreign issuer. EDRs are European receipts evidencing a similar arrangement with
a European bank. Generally,  ADRs, in registered form,  are designed for use  in
the U.S. securities market and EDRs, in bearer form, are designed for use in the
European securities market. ADRs may be sponsored or unsponsored. The issuers of
the stock of unsponsored ADRs are
 
                                       10
<PAGE>
not  obligated  to  disclose  material  information  in  the  United  States and
therefore, there  may not  be a  correlation between  such information  and  the
market  value of the ADR. In the event that ADRs or EDRs are not available for a
particular security, the Portfolio may invest in that security, which may or may
not be listed on a foreign securities exchange.
 
    The Portfolio may also invest up to 10% of its total assets in gold bullion.
Bullion will only be bought from and  sold to U.S. and foreign banks,  regulated
U.S.  commodities exchanges,  exchanges affiliated  with a  regulated U.S. stock
exchange, and dealers who are members  of, or affiliated with, a regulated  U.S.
commodities  exchange, in accordance with  applicable investment laws. Investors
should note  that  bullion offers  the  potential for  capital  appreciation  or
depreciation,  but unlike other investments does not generate income. In bullion
transactions, the Portfolio may encounter  higher custody costs and other  costs
(including shipping and insurance) than those costs that are normally associated
with  ownership  of  securities. The  Fund  may  attempt to  minimize  the costs
associated with  the  actual  custody of  bullion  by  the use  of  receipts  or
certificates representing ownership interests in bullion. The Advisers currently
intend  to  use the  Portfolio's  investments in  gold  bullion as  a short-term
investment for portfolio management purposes.
 
    The Portfolio  may also  invest up  to 30%  of its  assets in  money  market
instruments  under normal circumstances, although  the Portfolio intends to stay
invested in securities satisfying its primary investment objective to the extent
practicable. Money market instruments include obligations of the U.S. Government
and  its  agencies  and  instrumentalities,  commercial  paper  including   bank
obligations,  certificates  of  deposit  (including  Eurodollar  certificates of
deposit) and  repurchase  agreements.  For temporary  investment  purposes,  the
Portfolio may invest up to all of its assets in such instruments.
 
   
    For  hedging purposes  only, the  Portfolio may  enter into  forward foreign
currency exchange transactions, covered call and  put options (listed on a  U.S.
securities   exchange  or  written  in  the  over-the-counter  market),  futures
contracts and options on futures. The  Portfolio may also enter into  repurchase
agreements,  purchase securities on a when-issued  or delayed delivery basis and
lend its  portfolio securities.  For more  information on  these practices,  see
"Additional   Investment  Information"  below  and  "Investment  Objectives  and
Policies" in the Statement of Additional Information.
    
 
    Any remaining assets of the Portfolio not invested as described above may be
invested in certain securities or obligations.
 
                       ADDITIONAL INVESTMENT INFORMATION
 
    DEPOSITARY RECEIPTS.   The Portfolio  is permitted to  invest indirectly  in
securities  of  foreign  companies  through  sponsored  or  unsponsored American
Depositary Receipts  ("ADRs"), Global  Depositary  Receipts ("GDRs")  and  other
types   of  Depositary  Receipts  (which,  together  with  ADRs  and  GDRs,  are
hereinafter collectively referred  to as "Depositary  Receipts"), to the  extent
such  Depositary Receipts are  or become available.  Depositary Receipts are not
necessarily denominated in the  same currency as  the underlying securities.  In
addition,  the  issuers  of  the  securities  underlying  unsponsored Depositary
Receipts are not  obligated to disclose  material information in  the U.S.  and,
therefore,  there may be  less information available  regarding such issuers and
there may not be a correlation between such information and the market value  of
the Depositary Receipts. ADRs are Depositary Receipts typically issued by a U.S.
financial  institution which evidence ownership interests  in a security or pool
or securities issued  by a foreign  issuer. GDRs and  other types of  Depositary
 
                                       11
<PAGE>
Receipts are typically issued by foreign banks or trust companies, although they
also  may  be  issued by  U.S.  financial institutions,  and  evidence ownership
interests in a security or  pool of securities issued by  either a foreign or  a
U.S. corporation. Generally, Depositary Receipts in registered form are designed
for use in the U.S. securities market and Depositary Receipts in bearer form are
designed  for use  in securities  markets outside the  U.S. For  purposes of the
Portfolio's investment  policies,  the  Portfolio's  investments  in  Depositary
Receipts will be deemed to be investments in the underlying securities.
 
    FOREIGN  INVESTMENT.    Investment  in securities  of  foreign  issuers also
involves  somewhat  different  investment   risks  than  those  affecting   U.S.
investments. There may be limited publicly available information with respect to
foreign  issuers,  and  foreign issuers  are  not generally  subject  to uniform
accounting, auditing  and financial  standards  and requirements  comparable  to
those  applicable  to  domestic companies.  There  may also  be  less government
supervision and regulation of foreign  securities exchanges, brokers and  listed
companies  than in the  U.S. Many foreign  securities markets have substantially
less volume  than U.S.  national securities  exchanges, and  securities of  some
foreign  issuers are less liquid and more volatile than securities of comparable
domestic issuers. Brokerage commissions and  other transaction costs on  foreign
securities  exchanges  are  generally  higher than  in  the  U.S.  Dividends and
interest paid by foreign issuers may be subject to withholding and other foreign
taxes, which may decrease the net  return on foreign investments as compared  to
dividends  and interest paid to  the Portfolio by domestic  companies. It is not
expected that the Portfolio or its shareholders would be able to claim a  credit
for  U.S. tax  purposes with  respect to  any such  foreign taxes.  See "Taxes".
Additional  risks  include  future  political  and  economic  developments,  the
possibility that a foreign jurisdiction might impose or change withholding taxes
on  income  payable  with  respect  to  foreign  securities,  possible  seizure,
nationalization or expropriation of the  foreign issuer or foreign deposits  and
the  possible  adoption of  foreign governmental  restrictions such  as exchange
controls. Current  developments  in  South  Africa have  raised  the  threat  of
political  instability and uncertainty concerning the impact of such instability
on South Africa's economy and businesses. Accordingly, the risk of investing  in
securities  of issuers in South Africa may be greater than the risk of investing
in more stable foreign countries.
 
    Such investments in securities of foreign issuers are frequently denominated
in foreign currencies and because the Portfolio may temporarily hold  uninvested
reserves  in bank deposits  in foreign currencies, the  value of the Portfolio's
assets as measured in U.S. dollars  may be affected favorably or unfavorably  by
changes  in currency rates  and exchange control  regulations, and the Portfolio
may incur costs in connection with conversions between various currencies.
 
    FORWARD FOREIGN CURRENCY EXCHANGE CONTRACTS.   The Portfolio may enter  into
forward  foreign currency  exchange contracts that  provide for  the purchase or
sale of an amount of a specified  currency at a future date. Purposes for  which
such  contracts may be  used include protecting  against a decline  in a foreign
currency against the U.S. dollar between the trade date and settlement date when
the Portfolio purchases or sells non-U.S. dollar-denominated securities, locking
in the U.S. dollar  value of dividends  and interest on  securities held by  the
Portfolio  and generally protecting the U.S.  dollar value of securities held by
the Portfolio against exchange rate fluctuation. Such contracts may also be used
as a protective  measure against the  effects of fluctuating  rates of  currency
exchange  and  exchange control  regulations. While  such forward  contracts may
limit losses to  the Portfolio as  a result of  exchange rate fluctuation,  they
will also limit any gains that may otherwise have been realized. See "Investment
Objectives and Policies -- Forward Currency Exchange Contracts" in the Statement
of Additional Information.
 
                                       12
<PAGE>
    GOLD  RELATED INVESTMENTS.  The Portfolio intends  to invest at least 70% of
its total assets in securities of companies engaged in gold-related  activities.
As  a result of this policy, which is a fundamental policy of the Portfolio, the
Portfolio's investments may be  subject to greater  risk and market  fluctuation
than  a  fund  that  invests  in  securities  representing  a  broader  range of
investment alternatives.  Historically, stock  prices of  companies involved  in
precious  metals-related industries  have been  volatile. Investment  related to
gold and other precious metals and  minerals are considered speculative and  are
impacted  by a variety of world-wide economics, financial and political factors.
Prices of  gold and  other  precious metals  may  fluctuate sharply  over  short
periods  of time due to changes in inflation or expectations regarding inflation
in various countries, the availability  of supplies of precious metals,  changes
in  industrial and commercial demand, metal  sales by governments, central banks
or international agencies, investment  speculation, monetary and other  economic
policies of various governments and government restrictions on private ownership
of certain precious metals and minerals.
 
    LOANS  OF  PORTFOLIO  SECURITIES.   The  Portfolio  may  lend  securities to
brokers, dealers, domestic and foreign banks or other financial institutions for
the purpose of increasing its net investment income. These loans must be secured
continuously by cash or equivalent collateral, or by a letter of credit at least
equal to the  market value  of the securities  loaned plus  accrued interest  or
income.  There may be a risk of delay in recovery of the securities or even loss
of rights  in  the  collateral  should  the  borrower  of  the  securities  fail
financially.  The  Portfolio will  not enter  into securities  loan transactions
exceeding, in the aggregate, 33  1/3% of the market  value of its total  assets.
For   more  detailed  information  about   securities  lending  see  "Investment
Objectives and Policies" in the Statement of Additional Information.
 
    MONEY MARKET INSTRUMENTS.   The Portfolio  is permitted to  invest in  money
market   instruments,  although  the  Portfolio  intends  to  stay  invested  in
securities satisfying its primary investment objective to the extent  practical.
The  Portfolio may  make money market  investments pending  other investments or
settlement for  liquidity, or  in adverse  market conditions.  The money  market
investments permitted for the Portfolio include obligations of the United States
Government  and  its  agencies  and  instrumentalities;  obligations  of foreign
sovereignties;  other   debt  securities;   commercial  paper   including   bank
obligations;  certificates  of  deposit  (including  Eurodollar  certificates of
deposit), and repurchase agreements. For  more detailed information about  these
money  market investments,  see "Description of  Securities and  Ratings" in the
Statement of Additional Information.
 
   
    NON-PUBLICALY  TRADED   SECURITIES,   PRIVATE  PLACEMENTS   AND   RESTRICTED
SECURITIES.  The Portfolio may invest in securities that are neither listed on a
stock   exchange  nor   traded  over-the-counter,   including  privately  placed
securities. As a  result of the  absence of  a public trading  market for  these
securities,  they may be less liquid than publically traded securities. Although
these securities may be resold in privately negotiated transactions, the  prices
realized  from  these sales  could be  less  than those  originally paid  by the
Portfolio, or  less  than  what  may  be  considered  the  fair  value  of  such
securities.  The Portfolio  may not invest  more than  15% of its  net assets in
illiquid  securities,  including  securities  for  which  there  is  no  readily
available  secondary market nor more than 10%  of its total assets in securities
that are restricted from  sale to the  public without registration  ("Restricted
Securities")  under the  Securities Act  of 1933,  as amended  (the "1933 Act").
Nevertheless, subject  to  the  foregoing  limit  on  illiquid  securities,  the
Portfolio may invest up to 20% of its total assets in Restricted Securities that
can  be offered and sold to qualified institutional buyers under Rule 144A under
that Act ("144A Securities"). The Board of Directors has adopted guidelines  and
delegated to the Advisers, subject to the
    
 
                                       13
<PAGE>
supervision  of the  Board of Directors,  the daily function  of determining and
monitoring the  liquidity of  Rule  144A securities.  Rule 144A  securities  may
become  illiquid  if  qualified  institutional  buyers  are  not  interested  in
acquiring the securities.
 
    PRECIOUS METALS FORWARD AND FUTURES CONTRACTS.  The Portfolio may enter into
futures contracts on precious metals as a hedge against changes in the prices of
precious metals held or intended  to be acquired by  the Portfolio, but not  for
speculation  or for achieving  leverage. The Portfolio's  hedging activities may
include purchases  of futures  contracts  as an  offset  against the  effect  of
anticipated  increases  in the  price of  a precious  metal which  the Portfolio
intends to acquire or sales of futures contracts as an offset against the effect
of anticipated declines in the price of precious metal which the Portfolio owns.
The Portfolio  may  enter into  precious  metals forward  contracts,  which  are
similar  to precious metals futures contracts in  that they both provide for the
purchase or sale of  precious metals at  an agreed price  with delivery to  take
place  at  an agreed  future time.  However,  unlike futures  contracts, forward
contracts are  negotiated  contracts which  are  primarily used  in  the  dealer
market.  The Portfolio will use forward  contracts for the same hedging purposes
as those applicable to  futures contracts, as  described above. Precious  metals
futures  and  forward  contract  prices  can  be  volatile  and  are  influenced
principally by changes in spot  market prices, which in  turn are affected by  a
variety of political and economic factors. While the correlation between changes
in  prices of futures  and forward contracts  and prices of  the precious metals
being  hedged  by  such  contracts  has  historically  been  very  strong,   the
correlation  may be imperfect at  times, and even a  well conceived hedge may be
unsuccessful to some degree  because of market  behavior or unexpected  precious
metals price trends. For more detailed information about precious metals forward
and  futures  transactions  see  "Investment  Objectives  and  Policies"  in the
Statement of Additional Information.
 
    The Portfolio may  also purchase and  write covered call  or put options  on
precious  metals futures contracts.  Such options would  be purchased solely for
hedging purposes. Call options might be  purchased to hedge against an  increase
in  the  price of  precious metals  the  Portfolio intends  to acquire,  and put
options may be purchased  to hedge against  a decline in  the price of  precious
metals owned by the Portfolio. As is the case with futures contracts, options on
precious  metals futures may facilitate  the Portfolio's acquisition of precious
metals or permit the Portfolio to  defer disposition of precious metals for  tax
or other purposes.
 
    REPURCHASE  AGREEMENTS.  The Portfolio  may enter into repurchase agreements
with brokers, dealers  or banks that  meet the credit  guidelines of the  Fund's
Directors.  In  a repurchase  agreement, the  Portfolio buys  a security  from a
seller that has  agreed to  repurchase it  at a  mutually agreed  upon date  and
price, reflecting the interest rate effective for the term of the agreement. The
term of these agreements is usually from overnight to one week and never exceeds
one  year. Repurchase agreements may be viewed as a fully collateralized loan of
money by the Portfolio to the  seller. The Portfolio always receives  securities
with  a market  value at  least equal to  the purchase  price (including accrued
interest) as collateral,  and this value  is maintained during  the term of  the
agreement.  If  the  seller  defaults and  the  collateral  value  declines, the
Portfolio might  incur a  loss.  If bankruptcy  proceedings are  commenced  with
respect  to the seller,  the Portfolio's realization upon  the collateral may be
delayed or limited. The aggregate  of certain repurchase agreements and  certain
other investments is limited as set forth under "Investment Limitations."
 
    STOCK  OPTIONS,  STOCK  FUTURES  CONTRACTS  AND  OPTIONS  ON  STOCK  FUTURES
CONTRACTS.   The Portfolio  may  write (i.e.,  sell)  covered call  options  and
covered  put options on portfolio securities.  By selling a covered call option,
the Portfolio would become obligated during  the terms of the option to  deliver
the securities underlying
 
                                       14
<PAGE>
the  option should the  option holder choose  to exercise the  option before the
option's termination date. In return for the call it has written, the  Portfolio
will  receive from the purchaser (or option holder) a premium which is the price
of the option, less a  commission charged by a  broker. The Portfolio will  keep
the  premium regardless of whether the option is exercised. By selling a covered
put option, the Portfolio  incurs an obligation to  buy the security  underlying
the  option from the purchaser of the put  at the option's exercise price at any
time during  the option  period, at  the purchaser's  election (certain  options
written by the Portfolio will be exercisable by the purchaser only on a specific
date).  A call option is "covered" if the Portfolio owns the security underlying
the option it has written or has  an absolute or immediate right to acquire  the
security  by holding a call  option on such security,  or maintains a sufficient
amount of cash, cash equivalents or liquid securities to purchase the underlying
security. Generally, a put option is "covered" if the Portfolio maintains  cash,
U.S.  Government securities  or other high  grade debt obligations  equal to the
exercise price of the option or if the Portfolio holds a put option on the  same
underlying security with a similar or higher exercise price.
 
    When  the Portfolio writes  covered call options, it  augments its income by
the premiums received,  and is  thereby hedged, to  the extent  of that  amount,
against  a  decline in  the  price of  the  underlying securities.  The premiums
received will offset a portion of  the potential loss incurred by the  Portfolio
if the securities underlying the options are ultimately sold by the Portfolio at
a  loss. However, during the option period, the Portfolio has, in return for the
premium on the option, given up  the opportunity for capital appreciation  above
the  exercise price should the market price of the underlying security increase,
but has retained the risk  of loss should the  price of the underlying  security
decline.
 
    The  Portfolio  will  write put  options  to  receive the  premiums  paid by
purchasers (when  the Advisers  wish  to purchase  the security  underlying  the
option  at  a price  lower  than its  current market  price,  in which  case the
Portfolio will write the covered put  at an exercise price reflecting the  lower
purchase price sought) and to close out a long put option position.
 
    The  Portfolio  may  also purchase  put  or  call options  on  its portfolio
securities. When the Portfolio purchases a call option it acquires the right  to
buy a designated security at a designated price (the "exercise price"), and when
the  Portfolio purchases a put option it acquires the right to sell a designated
security at the exercise price, in each case on or before a specified date  (the
"termination  date"), usually not more than nine months from the date the option
is issued. The Portfolio may purchase call  options to close out a covered  call
position  or  to protect  against  an increase  in the  price  of a  security it
anticipates purchasing. The  Portfolio may  purchase put  options on  securities
which  it holds in  its portfolio only to  protect itself from  a decline in the
value of the  security. If the  value of  the underlying security  were to  fall
below  the exercise  price of the  put purchased  in an amount  greater than the
premium paid for the option, the  Portfolio would incur no additional loss.  The
Portfolio  may also purchase put options to close out written put positions in a
manner similar to call option closing purchase transactions. There are no  other
limits on the Portfolio's ability to purchase call and put options.
 
   
    The  Portfolio  may  enter into  futures  contracts and  options  on futures
contracts as a hedge  against fluctuations in  price of a  security it holds  or
intends  to  acquire, but  not for  speculation or  for achieving  leverage. The
Portfolio may also enter into futures transactions to remain fully invested  and
to  reduce transaction costs. The Portfolio may enter into futures contracts and
options on futures contracts provided that  not more than 5% of the  Portfolio's
total  assets at the time of entering into the contract or option is required as
deposit to secure  obligations under  such contracts and  options, and  provided
that  not more  than 20%  of the  Portfolio's total  assets in  the aggregate is
invested in options, futures contracts and options on futures contracts.
    
 
                                       15
<PAGE>
    The Portfolio  may  purchase and  write  call  and put  options  on  futures
contracts   that  are  traded  on  a  U.S.  exchange,  and  enter  into  closing
transactions with respect to such options to terminate an existing position.  An
option  on a futures contract  gives the purchaser the  right (in return for the
premium paid) to assume a  position in future contract  (a long position if  the
option  is a call and  a short position if  the option is a  put) at a specified
exercise price at any  time during the  term of the  option. The Portfolio  will
purchase  and write options on  futures contracts for the  purchase of a futures
contract (purchase of a call option or sale of a put option) and for the sale of
a futures contract (purchase of  a put option or sale  of a call option), or  to
close out a long or short position in future contracts for identical purposes to
those set forth above.
 
    The  primary risks associated with the use of option, futures and options on
futures are (i) imperfect correlation between the change in market value of  the
stocks  held by the Portfolio, and the prices of futures and options relating to
the stocks purchased  or sold  by the  Portfolio; and  (ii) possible  lack of  a
liquid  secondary market for  a futures contract and  the resulting inability to
close a futures position which could  have an adverse impact on the  Portfolio's
ability  to hedge. In the  opinion of the Board of  Directors, the risk that the
Portfolio will be  unable to close  out a futures  position or options  contract
will   be  minimized  by  only  entering   into  futures  contracts  or  options
transactions for which there appears to be a liquid secondary market.
 
   
    TEMPORARY INVESTMENTS.  During periods in which the Adviser believes changes
in economic, financial or political conditions make it advisable, the  Portfolio
may  reduce its holdings in equity and other securities, for temporary defensive
purposes, and the Portfolio may invest  in certain short-term (less than  twelve
months  to maturity) and  medium-term (not greater than  five years to maturity)
debt securities or may hold cash. The short-term and medium-term debt securities
in which  the Portfolio  may invest  consist of  (a) obligations  of the  United
States   or   foreign  country   governments,   their  respective   agencies  or
instrumentalities;  (b)   bank   deposits  and   bank   obligations   (including
certificates  of  deposit, time  deposits  and bankers'  acceptances)  of United
States or foreign country banks denominated  in any currency; (c) floating  rate
securities   and  other  instruments  denominated  in  any  currency  issued  by
international development agencies; (d) finance company and corporate commercial
paper and  other short-term  corporate  debt obligations  of United  States  and
foreign  country corporations meeting the  Portfolio's credit quality standards;
and (e) repurchase agreements with banks and broker-dealers with respect to such
securities. For temporary  defensive purposes, the  Portfolios intend to  invest
only  in short-term and medium-term debt securities that the Adviser believes to
be of high quality, i.e., subject to relatively low risk of loss of interest  or
principal.  There  is currently  no rating  system for  debt securities  in most
foreign countries.
    
 
    WHEN-ISSUED AND DELAYED  DELIVERY SECURITIES.   The  Portfolio may  purchase
securities  on a  when-issued or delayed  delivery basis.  In such transactions,
instruments are bought with payment and  delivery taking place in the future  in
order  to secure what is considered to be  an advantageous yield or price at the
time of the transaction. Delivery of  and payment for these securities may  take
as  long as a month or  more after the date of  the purchase commitment but will
take place  no more  than 120  days after  the trade  date. The  Portfolio  will
maintain  with the Custodian  a separate account with  a segregated portfolio of
high-grade equity  securities or  cash in  an  amount at  least equal  to  these
commitments. The payment obligation and the interest rates that will be received
are  each fixed  at the  time the  Portfolio enters  into the  commitment and no
interest accrues to the  Portfolio until settlement. Thus,  it is possible  that
the  market value at  the time of settlement  could be higher  or lower than the
purchase price if, among other factors, the general level of interest rates  has
changed. It is a
 
                                       16
<PAGE>
current  policy  of  the Portfolio  not  to enter  into  when-issued commitments
exceeding in the  aggregate 15%  of the market  value of  the Portfolio's  total
assets   less  liabilities,  other   than  the  obligations   created  by  these
commitments.
 
                             INVESTMENT LIMITATIONS
 
    As a diversified investment  company, the Gold Portfolio  is subject to  the
following  limitations: (a) as to 75% of its total assets, the Portfolio may not
invest more than 5%  of its total  assets in the securities  of any one  issuer,
except   obligations   of   the   U.S.   Government   and   its   agencies   and
instrumentalities, and  (b) the  Portfolio may  not  own more  than 10%  of  the
outstanding voting securities of any one issuer.
 
   
    The  Portfolio also operates under  certain investment restrictions that are
deemed fundamental limitations and may be changed only with the approval of  the
holders  of a  majority of the  Portfolio's outstanding  shares. See "Investment
Limitations" in  the  Statement  of Additional  Information.  In  addition,  the
Portfolio  operates  under  certain  non-fundamental  investment  limitations as
described below and in  the Statement of  Additional Information. The  Portfolio
may  not  (i) enter  into repurchase  agreements  with more  than seven  days to
maturity if, as a result, more than  15% of the market value of the  Portfolio's
net assets would be invested in such repurchase agreements and other investments
for  which market  quotations are not  readily available or  which are otherwise
illiquid; (ii) borrow money,  except from banks  for extraordinary or  emergency
purposes,  and then only  in amounts up to  10% of the  value of the Portfolio's
total assets, taken  at cost at  the time of  borrowing, or purchase  securities
while  borrowings  exceed 5%  of  its total  assets;  (iii) mortgage,  pledge or
hypothecate any assets except in connection  with any such borrowing in  amounts
up  to 10% of the value of the  Portfolio's net assets at the time of borrowing;
(iv) invest in fixed time deposits with a duration of over seven calendar  days;
or  (v) invest in fixed time deposits with  a duration of from two business days
to seven calendar days if more than 10% of the Portfolio's total assets would be
invested in these deposits.
    
 
                             MANAGEMENT OF THE FUND
 
   
    INVESTMENT ADVISER AND SUB-ADVISER.  Morgan Stanley Asset Management Inc. is
the Investment Adviser and Administrator of the Fund and each of its portfolios.
The Adviser  provides  investment  advice  and  portfolio  management  services,
pursuant  to an Investment Advisory Agreement and, subject to the supervision of
the Fund's  Board  of  Directors,  makes  each  of  the  Portfolio's  day-to-day
investment  decisions, arranges for the  execution of portfolio transactions and
generally manages  each of  the  Portfolio's investments.  With respect  to  the
Portfolio,  the  Adviser has  delegated these  responsibilities, subject  to its
supervision, to the  Sub-Adviser. The Adviser  is entitled to  receive from  the
Portfolio  an annual  investment advisory fee,  payable quarterly,  in an amount
equal to 1.00% of the average daily net assets of the Portfolio.
    
 
    Sun Valley  Gold Company  is sub-adviser  of the  Portfolio. Pursuant  to  a
Sub-Advisory  Agreement,  and subject  at all  times to  the supervision  of the
Adviser and  the  Board of  Directors  of  the Fund,  the  Sub-Adviser  provides
investment  advice  and  portfolio management  services,  makes  the Portfolio's
day-to-day  investment  decisions,  arranges  for  the  execution  of  portfolio
transactions  and generally manages the Portfolio's investments. The Sub-Adviser
is entitled to  receive from  the Adviser  an annual  sub-advisory fee,  payable
quarterly,  in an amount equal  to 0.40% of the average  daily net assets of the
Portfolio.
 
                                       17
<PAGE>
   
    The Adviser has  agreed to  a reduction  in the fees  payable to  it and  to
reimburse the Portfolio, if necessary, if such fees would cause the total annual
operating  expenses for Class  A and Class  B shares to  exceed 1.25% and 1.50%,
respectively, of its average daily net  assets. The Sub-Adviser has agreed to  a
proportionate  reduction in its fees from the Adviser if the Adviser is required
to waive its fees or  to reimburse the Portfolio  so that the Portfolio's  total
operating expenses for Class A and Class B shares do not exceed 1.25% and 1.50%,
respectively, of its average daily net assets.
    
 
   
    The  Adviser, with  principal offices  at 1221  Avenue of  the Americas, New
York, New York  10020, conducts  a worldwide portfolio  management business.  It
provides  a broad  range of  portfolio management  services to  customers in the
United States and abroad. At December  31, 1995, the Adviser, together with  its
affiliated    asset   management   companies,   managed   investments   totaling
approximately $57.4 billion, including approximately $41.9 billion under  active
management  and  $15.5  billion as  Named  Fiduciary or  Fiduciary  Adviser. See
"Management of the Fund" in the Statement of Additional Information.
    
 
   
    The Sub-Adviser, with principal offices at 620 Sun Valley Road, Sun  Valley,
Idaho 83340, specializes in the management of gold-related investments. At March
31,  1996,  the  Sub-Adviser  managed  investments  totaling  approximately $192
million.
    
 
    PORTFOLIO MANAGER.  Peter F. Palmedo, the President of the Sub-Adviser since
its  inception  in   January,  1992,  has   had  primary  portfolio   management
responsibility  for the  Portfolio since  its inception.  He has  also served as
President of Sun Valley  Gold Trading, Inc.,  a registered broker-dealer,  since
its  inception in  January, 1992, and  of Mad River  Management since September,
1989. Prior thereto, Mr. Palmedo worked  at Morgan Stanley in the  institutional
equity  department and specialized in portfolio risk management, derivatives and
the development  and  analysis  of long-dated  options,  synthetic  options  and
options  embedded in securities. He  received a BA in  Business and Finance from
Hampshire College in 1979.
 
   
    ADMINISTRATOR.   The  Adviser also  provides  the Fund  with  administrative
services  pursuant to an  Administration Agreement. The  services provided under
the Administration Agreement are subject to the supervision of the Officers  and
the  Board of  Directors of  the Fund  and include  day-to-day administration of
matters related  to the  corporate existence  of the  Fund, maintenance  of  its
records,  preparation of report, supervision of the Fund's arrangements with its
custodian,  and  assistance  in  the  preparation  of  the  Fund's  registration
statements  under  federal and  state  laws. The  Administration  Agreement also
provides that  the Administrator,  through  its agents,  will provide  the  Fund
dividend  disbursing and  transfer agent  services. For  its services  under the
Administration Agreement, the Fund  pays the Adviser a  monthly fee which on  an
annual basis equals 0.15% of the average daily net assets of the Portfolio.
    
 
   
    Under  an agreement between  the Adviser and The  Chase Manhattan Bank, N.A.
("Chase"), Chase  provides certain  administrative services  to the  Fund. In  a
merger  completed on September 1, 1995, Chase succeeded to all of the rights and
obligations under the  U.S. Trust Administration  Agreement between the  Adviser
and  the United  States Trust  Company of New  York ("U.S.  Trust"), pursuant to
which U.S. Trust had  agreed to provide certain  administrative services to  the
Fund.  Pursuant  to  a  delegation  clause  in  the  U.S.  Trust  Administration
Agreement, U.S.  Trust delegated  its administration  responsibilities to  Chase
Global  Funds Services Company ("CGFSC"), formerly known as Mutual Funds Service
Company which after  the merger with  Chase is  a subsidiary of  Chase and  will
continue  to provide  certain administrative services  to the  Fund. The Adviser
supervises and  monitors such  administrative services  provided by  CGFSC.  The
services provided under the
    
 
                                       18
<PAGE>
   
Administration  Agreement and the  U.S. Trust Administration  Agreement are also
subject to the supervision of the Board  of Directors of the Fund. The Board  of
Directors  of the  Fund has approved  the provision of  services described above
pursuant to  the  Administration Agreement  and  the U.S.  Trust  Administration
Agreement as being in the best interest of the Fund. CGFSC's business address is
73  Tremont Street, Boston, Massachusetts 02108-3913. For additional information
regarding  the  Administration  Agreement  or  the  U.S.  Trust   Administration
Agreement,  see  "Management  of  the  Fund"  in  the  Statement  of  Additional
Information.
    
 
    DIRECTORS AND OFFICERS.  Pursuant  to the Fund's Articles of  Incorporation,
the  Board of Directors decides  upon matters of general  policy and reviews the
actions of the Fund's  Adviser, Administrator and  Distributor. The Officers  of
the Fund conduct and supervise its daily business operations.
 
    DISTRIBUTOR.   Morgan  Stanley serves  as the  exclusive Distributor  of the
shares of  the Fund.  Under its  Distribution Agreement  with the  Fund,  Morgan
Stanley sells shares of the Portfolio upon the terms and at the current offering
price  described in this Prospectus. Morgan Stanley is not obligated to sell any
certain number of shares of the Portfolio.
 
    The Portfolio currently offers  only the classes of  shares offered by  this
Prospectus.  The Portfolio may in the future offer one or more classes of shares
with features, distribution expenses or  other expenses that are different  from
those of the classes currently offered.
 
   
    The  Fund has  adopted a Plan  of Distribution  with respect to  the Class B
shares pursuant to Rule 12b-1 under the  1940 Act (the "Plan"). Under the  Plan,
the  Distributor is entitled  to receive from the  Portfolio a distribution fee,
which is accrued  daily and  paid quarterly,  of 0.25%  of the  Class B  shares'
average  daily net  assets on  an annualized  basis. The  Distributor expects to
reallocate most of its  fee to its  investment representatives. The  Distributor
may,  in its discretion, voluntarily waive from  time to time all or any portion
of its distribution fee and each of  the Distributor and the Adviser is free  to
make  additional payments  out of  its own  assets to  promote the  sale of Fund
shares,  including   payments  that   compensate  financial   institutions   for
distribution services or shareholder services.
    
 
    The  plan is designed to compensate the Distributor for its services, not to
reimburse the Distributor for its expenses,  and the Distributor may retain  any
portion  of the fee that it does not expend in fulfillment of its obligations to
the Fund.
 
    EXPENSES.  The Portfolio  is responsible for payment  of certain other  fees
and  expenses  (including legal  fees,  accountants' fees,  custodial  fees, and
printing and mailing  costs) specified  in the  Administration and  Distribution
Agreements.
 
                                       19
<PAGE>
                               PURCHASE OF SHARES
 
   
    Class  A and Class B shares of the Portfolio may be purchased, without sales
commission, at the net  asset value per share  next determined after receipt  of
the purchase order by the Portfolio. See "Valuation of Shares."
    
 
   
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
    
 
   
    For  a  Portfolio  account  opened  on or  after  January  2,  1996  (a "New
Account"), the minimum initial investment and minimum account size are  $500,000
for  Class  A shares  and  $100,000 for  Class  B shares.  Managed  Accounts may
purchase Class A shares without being subject to any minimum initial  investment
or  minimum account size  requirements for a Portfolio  account. Officers of the
Adviser and its affiliates are subject to the minimums for a Portfolio  account,
except  they may purchase Class B shares subject to a minimum initial investment
and minimum account size of $5,000 for a Portfolio account.
    
 
   
    If the value of a New Account containing Class A shares falls below $500,000
(but remains at  or above  $100,000) because of  shareholder redemption(s),  the
Fund  will  notify  the shareholder,  and  if  the account  value  remains below
$500,000 (but remains at or above $100,000) for a continuous 60-day period,  the
Class  A shares  in such  account will  convert to  Class B  shares and  will be
subject to the  distribution fee and  other features applicable  to the Class  B
shares.  The Fund, however,  will not convert  Class A shares  to Class B shares
based solely upon  changes in  the market  that reduce  the net  asset value  of
shares.  Under  current tax  law, conversions  between share  classes are  not a
taxable event to the shareholder.
    
 
   
    Shares in a Portfolio account opened  prior to January 2, 1996 (a  "Pre-1996
Account")  were  designated Class  A  shares on  January  2, 1996.  Shares  in a
Pre-1996 Account  with  a  value  of  $100,000 or  more  on  March  1,  1996  (a
"Grandfathered  Class A Account") remained Class  A shares regardless of account
size thereafter. Except for  shares in a Managed  Account, shares in a  Pre-1996
Account  with a value of  less than $100,000 on  March 1, 1996 (a "Grandfathered
Class B Account") converted  to Class B shares  on March 1, 1996.  Grandfathered
Class A Accounts and Managed Accounts are not subject to conversion from Class A
shares to Class B shares.
    
 
   
    Investors  may also invest in the Fund  by purchasing shares through a trust
department, broker, dealer, agent, financial planner, financial services firm or
investment adviser.  An  investor  may  be  charged  an  additional  service  or
transaction fee by that institution. The minimum investment levels may be waived
at  the discretion  of the  Adviser for (i)  certain employees  and customers of
Morgan Stanley  or  its  affiliates  and  certain  trust  departments,  brokers,
dealers,  agents, financial  planners, financial  services firms,  or investment
advisers that  have  entered  into  an agreement  with  Morgan  Stanley  or  its
affiliates;  and (ii) retirement and deferred compensation plans and trusts used
to fund such  plans, including,  but not limited  to, those  defined in  Section
401(a),  403(b) or  457 of the  Internal Revenue  Code of 1986,  as amended, and
"rabbi trusts".  The  Fund  reserves  the  right  to  modify  or  terminate  the
conversion  features of  the shares  as stated above  at any  time upon 60-days'
notice to shareholders.
    
 
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
 
   
    If the value of  a New Account falls  below $100,000 because of  shareholder
redemption(s),  the Fund will  notify the shareholder, and  if the account value
remains below  $100,000 for  a  continuous 60-day  period,  the shares  in  such
account  are subject to redemption  by the Fund and,  if redeemed, the net asset
value of  such  shares will  be  promptly paid  to  the shareholder.  The  Fund,
however,  will not redeem  shares based solely  upon changes in  the market that
reduce the net asset value of shares.
    
 
                                       20
<PAGE>
   
    For purposes of redemptions by the Fund, the foregoing minimum account  size
requirements  do not  apply to  New Accounts containing  Class B  shares held by
officers of the Adviser or its affiliates. However, if the value of such account
held by an officer of the Adviser  or its affiliates falls below $5,000  because
of  shareholder redemption(s), the Fund will  notify the shareholder, and if the
account value remains $5,000 for a continuous 60-day period, the shares in  such
account  are subject to redemption  by the Fund and,  if redeemed, the net asset
value of such shares will be promptly paid to the shareholder.
    
 
   
    Grandfathered Class A Accounts, Grandfathered  Class B Accounts and  Managed
Accounts are not subject to involuntary redemption.
    
 
   
    The  Fund  reserves  the  right  to  modify  or  terminate  the  involuntary
redemption features of  the shares  as stated above  at any  time upon  60-days'
notice to shareholders.
    
 
CONVERSION FROM CLASS B TO CLASS A SHARES
 
   
    If the value of Class B shares in a Portfolio account increases, whether due
to  shareholder share  purchases or  market activity,  to $500,000  or more, the
Class B shares  will convert  to Class  A shares.  Under current  tax law,  such
conversion  is not a taxable event to  the shareholder. Class A shares converted
from Class B shares  are subject to the  same minimum account size  requirements
that  are applicable to New Accounts containing Class A shares, as stated above.
The Fund reserves the  right to modify or  terminate this conversion feature  at
any time upon 60-days' notice to shareholders.
    
 
INITIAL PURCHASES DIRECTLY FROM THE FUND
 
   
    The  Fund's determination of an investor's eligibility to purchase shares of
a given class  will take precedence  over the investor's  selection of a  class.
Assuming  the investor is eligible for the  class, the Fund will select the most
favorable class for the investor, if the investor has not done so.
    
 
   
1) BY CHECK.   An account may  be opened  by completing and  signing an  Account
   Registration  Form, and mailing  it, together with  a check ($500,000 minimum
   for Class A shares of  the Portfolio and $100,000 for  Class B shares of  the
   Portfolio,  with certain exceptions  for Morgan Stanley  employees and select
   customers) payable  to  "Morgan  Stanley Institutional  Fund,  Inc.  --  Gold
   Portfolio", to:
    
 
   
       Morgan Stanley Institutional Fund, Inc.
        P.O. Box 2798
        Boston, Massachusetts 02208-2798
    
 
   
Payment will be accepted only in U.S. dollars, unless prior approval for payment
by  other  currencies is  given  by the  Fund. The  class(es)  of shares  of the
Portfolio to be purchased should be designated on the Account Registration Form.
For purchases  by check,  the Fund  is ordinarily  credited with  Federal  Funds
within  one business day. Thus,  your purchase of shares  by check is ordinarily
credited to your  account at  the net  asset value  per share  of the  Portfolio
determined on the next business day after receipt.
    
 
                                       21
<PAGE>
2) BY  FEDERAL  FUNDS WIRE.   Purchases  may be  made by  having your  bank wire
   Federal Funds to the Fund's bank  account. In order to ensure prompt  receipt
   of your Federal Funds Wire, it is important that you follow these steps:
 
   
A.   Telephone  the Fund  (toll free: 1-800-548-7786)  and provide  us with your
    name, address,  telephone  number,  Social Security  or  Tax  Identification
    Number,  the  Portfolio(s) selected,  the class  selected, the  amount being
    wired, and by  which bank.  We will  then provide  you with  a Fund  account
    number.  (Investors with existing accounts should also notify the Fund prior
    to wiring funds.)
    
 
   
B.   Instruct  your  bank to  wire  the  specified amount  to  the  Fund's  Wire
    Concentration  Bank Account (be sure  to have your bank  include the name of
    the portfolio(s)  selected,  the  class  selected  and  the  account  number
    assigned to you) as follows:
    
 
   
      Chase Manhattan Bank, N.A.
       One Manhattan Plaza
       New York, NY 10081-1000
       ABA #021000021
       DDA #910-2-733293
       Attn: Morgan Stanley Institutional Fund, Inc.
       Ref: (Portfolio name, your account number, your account name)
    
 
   
       Please call the Fund at 1-800-548-7786 prior to wiring funds.
    
 
   
C.   Complete and sign the Account Registration  Form and mail it to the address
    shown thereon.
    
 
   
Purchase orders for  shares of  the Portfolio which  are received  prior to  the
regular close of the NYSE (currently 4:00 p.m. Eastern Time) will be executed at
the price computed on the date of receipt as long as the Transfer Agent receives
payment  by check or in Federal Funds prior  to the regular close of the NYSE on
such day.
    
 
   
Federal Funds purchase orders will be accepted  only on a day on which the  Fund
and  Chase (the "Custodian Bank") are open  for business. Your bank may charge a
service fee for wiring funds.
    
 
3) BY BANK WIRE.   The  same procedure outlined  under "By  Federal Funds  Wire"
   above  must be  followed in  purchasing shares  by bank  wire. However, money
   transferred by bank wire may or may  not be converted into Federal Funds  the
   same  day, depending on the time the  money is received and the bank handling
   the wire. Prior to such conversion, an investor's money will not be invested.
   Your bank may charge a service fee for wiring funds.
 
ADDITIONAL INVESTMENTS
 
   
    You may  add to  your account  at any  time (minimum  additional  investment
$1,000,  except  for  automatic  reinvestment  of  dividends  and  capital gains
distributions for which there are no minimums) by purchasing shares at net asset
value by mailing a check to  the Fund (payable to "Morgan Stanley  Institutional
Fund,  Inc. -- Gold Portfolio") at the above  address or by wiring monies to the
Custodian Bank as outlined above. It  is very important that your account  name,
the  portfolio name and the class selected be specified in the letter or wire to
ensure proper  crediting to  your account.  In order  to ensure  that your  wire
orders are invested promptly, you are
    
 
                                       22
<PAGE>
   
requested   to   notify  one   of   the  Fund's   representatives   (toll  free:
1-800-548-7786) prior to the wire  date. Additional investments will be  applied
to  purchase additional  shares in  the same  class held  by a  shareholder in a
Portfolio account.
    
 
OTHER PURCHASE INFORMATION
 
   
    The purchase price of the Class A and Class B shares of the Portfolio is the
net asset value next determined after  the order is received. See "Valuation  of
Shares."  An order  received prior to  the regular  close of the  New York Stock
Exchange ("NYSE"), which is currently 4:00 p.m. (Eastern Time), will be executed
at the  price computed  on the  date of  receipt; an  order received  after  the
regular close of the NYSE will be executed at the price computed on the next day
the  NYSE is open as long as the  Transfer Agent receives payment by check or in
Federal Funds prior to the regular close of the NYSE on such day.
    
 
   
    Although the legal rights of Class A  and Class B shares will be  identical,
the  different expenses borne by  each class will result  in different net asset
values and dividends. The net  asset value of Class  B shares will generally  be
lower than the net asset value of Class A shares as a result of the distribution
expense  charged to Class B shares. It  is expected, however, that the net asset
value per share of the two classes  will tend to converge immediately after  the
recording  of dividends  which will  differ by  approximately the  amount of the
distribution expense accrual differential between the classes.
    
 
   
    In the interest  of economy and  convenience, and because  of the  operating
procedures  of the Fund, certificates representing  shares of the Portfolio will
not be issued. All shares  purchased are confirmed to  you and credited to  your
account  on the Fund's books  maintained by the Adviser  or its agents. You will
have  the  same  rights  and  ownership  with  respect  to  such  shares  as  if
certificates had been issued.
    
 
   
    To  ensure that checks are collected by the Fund, withdrawals of investments
made by check  are not presently  permitted until payment  for the purchase  has
been  received,  which may  take up  to eight  business days  after the  date of
purchase. As a  condition of this  offering, if  a purchase is  canceled due  to
nonpayment or because your check does not clear, you will be responsible for any
loss  the Fund or its  agents incur. If you are  already a shareholder, the Fund
may redeem shares from your account(s) to  reimburse the Fund or its agents  for
any  loss. In addition, you  may be prohibited or  restricted from making future
investments in the Fund.
    
 
   
    Investors may  also invest  in the  Fund by  purchasing shares  through  the
Distributor.   See  "Purchase  of   Shares"  in  the   Statement  of  Additional
Information.
    
 
EXCESSIVE TRADING
 
   
    Frequent  trades  involving  either   substantial  portfolio  assets  or   a
substantial  portion of your  account or accounts controlled  by you can disrupt
management of a portfolio and raise its expenses. Consequently, in the  interest
of  all the stockholders  of the Portfolio and  the Portfolio's performance, the
Fund may in its discretion bar  a stockholder that engages in excessive  trading
of  shares of any class  of a portfolio from further  purchases of shares of the
Fund for an indefinite period. The  Fund considers excessive trading to be  more
than  one purchase and sale involving shares of the same class of a portfolio of
the Fund  within  any  120-day  period. As  an  example,  exchanging  shares  of
portfolios of the Fund as follows amounts to excessive trading: exchanging Class
A shares of Portfolio A for Class A shares of Portfolio B, then exchanging Class
A  shares of Portfolio B for Class A  shares of Portfolio C and again exchanging
Class A shares of Portfolio C for Class A shares of Portfolio B within a 120-day
    
 
                                       23
<PAGE>
   
period. Two  types  of transactions  are  exempt from  these  excessive  trading
restrictions;  (1) trades exclusively  between money market  portfolios; and (2)
trades done  in  connection  with  an asset  allocation  service,  such  as  TFM
Accounts, managed or advised by MSAM and/or any of its affiliates.
    
 
                              REDEMPTION OF SHARES
 
   
    You  may  withdraw all  or  any portion  of the  amount  in your  account by
redeeming shares at any time. Please note  that purchases made by check are  not
permitted to be redeemed until payment of the purchase price has been collected,
which  may take up to  eight business days after  purchase. The Fund will redeem
Class A shares or  Class B shares  of the Portfolio at  the next determined  net
asset  value of shares of  the applicable class. On days  that both the NYSE and
the Custodian Bank are open for business,  the net asset value per share of  the
Portfolio  is determined at the regular close  of trading of the NYSE (currently
4:00 p.m. Eastern  Time). Shares of  the Portfolio  may be redeemed  by mail  or
telephone. No charge is made for redemption. Any redemption proceeds may be more
or  less  than the  purchase  price of  your  shares depending  on,  among other
factors, the market value of the investment securities held by the Portfolio.
    
 
BY MAIL
 
   
    The Portfolio will redeem its  Class A shares or Class  B shares at the  net
asset  value determined on the  date the request is  received, if the request is
received in "good  order" before  the regular close  of the  NYSE. Your  request
should  be addressed to Morgan Stanley  Institutional Fund, Inc., P.O. Box 2798,
Boston, Massachusetts 02208-2798,  except that deliveries  by overnight  courier
should be addressed to Morgan Stanley Institutional Fund, Inc., c/o Chase Global
Funds Services Company, 73 Tremont Street, Boston, Massachusetts 02108-3913.
    
 
   
    "Good  order"  means that  the  request to  redeem  shares must  include the
following documentation:
    
 
   
        (a)  A letter of instruction or a stock assignment specifying the  class
    and  number  of  shares or  dollar  amount  to be  redeemed,  signed  by all
    registered owners  of  the shares  in  the exact  names  in which  they  are
    registered;
    
 
   
        (b)   Any  required   signature  guarantees   (see  "Further  Redemption
    Information" below); and
    
 
   
        (c)   Other supporting  legal documents,  if required,  in the  case  of
    estates,  trusts, guardianships,  custodianships, corporations,  pension and
    profit-sharing plans and other organizations.
    
 
   
    Shareholders who are uncertain of requirements for redemption should consult
with a Morgan Stanley Institutional Fund representative.
    
 
BY TELEPHONE
 
    Provided you have previously elected the Telephone Redemption Option on  the
Account  Registration  Form, you  can  request a  redemption  of your  shares by
calling the Fund  and requesting  the redemption proceeds  be mailed  to you  or
wired  to your bank.  Please contact one of  Morgan Stanley Institutional Fund's
representatives for further details. In times of drastic market conditions,  the
telephone  redemption option  may be difficult  to implement.  If you experience
difficulty in making a telephone redemption, your request may be made by mail or
overnight courier and will be implemented at the net asset value next determined
after it is  received. Redemption requests  sent to the  Fund through  overnight
courier  must  be sent  to Morgan  Stanley Institutional  Fund, Inc.,  c/o Chase
Global  Funds  Services  Company,  73  Tremont  Street,  Boston,   Massachusetts
02108-3913.
 
                                       24
<PAGE>
The  Fund  and the  Fund's  transfer agent  (the  "Transfer Agent")  will employ
reasonable procedures to confirm that the instructions communicated by telephone
are genuine. These procedures include requiring the investor to provide  certain
personal  identification information at the time  an account is opened and prior
to effecting each transaction requested by telephone. In addition, all telephone
transaction requests will be recorded and  investors may be required to  provide
additional  telecopied  written  instructions  regarding  transaction  requests.
Neither the  Fund nor  the Transfer  Agent  will be  responsible for  any  loss,
liability, cost or expense for following instructions received by telephone that
either of them reasonably believes to be genuine.
 
    To  change the commercial  bank or account  designated to receive redemption
proceeds, a written  request must  be sent  to the  Fund at  the address  above.
Requests  to change the bank  or account must be  signed by each shareholder and
each signature must be guaranteed.
 
FURTHER REDEMPTION INFORMATION
 
    Normally the  Fund will  make payment  for all  shares redeemed  within  one
business  day of receipt  of the request, but  in no event  will payment be made
more than  seven days  after receipt  of  a redemption  request in  good  order.
However,  payments to investors  redeeming shares which  were purchased by check
will not be made until  payment for the purchase  has been collected, which  may
take up to eight days after the date of purchase. The Fund may suspend the right
of  redemption or postpone the date upon which redemptions are effected at times
when the NYSE is closed, or  under any emergency circumstances as determined  by
the Securities and Exchange Commission (the "Commission").
 
    If  the Board of  Directors determines that  it would be  detrimental to the
best interests of the  remaining shareholders of the  Portfolio to make  payment
wholly  or partly in cash, the Fund may  pay the redemption proceeds in whole or
in part by a distribution in-kind of securities held by the Portfolio in lieu of
cash   in    conformity   with    applicable    rules   of    the    Commission.
Distributions-in-kind  will be made in  readily marketable securities. Investors
may incur brokerage charges on the  sale of portfolio securities so received  in
payment of redemptions.
 
    To  protect  your account,  the Fund  and its  agents from  fraud, signature
guarantees are required for  certain redemptions to verify  the identity of  the
person  who has  authorized a redemption  from your account.  Please contact the
Fund for further  information. See "Redemption  of Shares" in  the Statement  of
Additional Information.
 
                              SHAREHOLDER SERVICES
 
EXCHANGE FEATURES
 
   
    You  may exchange  shares that you  own in  the Portfolio for  shares of any
other available  portfolio of  the  Fund (other  than the  International  Equity
Portfolio,  which is  closed to  new investors). In  exchanging for  shares of a
portfolio with more  than one  class, the  class of  shares you  receive in  the
exchange  will be determined in the same  manner as any other purchase of shares
and will not  be based  on the  class of  shares surrendered  for the  exchange.
Consequently,  the same minimum initial investment  and minimum account size for
determining the  class  of shares  received  in  the exchange  will  apply.  See
"Purchase  of Shares."  Shares of  the portfolios  may be  exchanged by  mail or
telephone. The privilege to exchange shares  by telephone is automatic and  made
available  without shareholder election. Before you make an exchange, you should
read the prospectus of the portfolio(s) in which you seek to invest. Because  an
exchange  transaction  is treated  as a  redemption followed  by a  purchase, an
    
 
                                       25
<PAGE>
   
exchange would be considered  a taxable event for  shareholders subject to  tax.
The  exchange privilege  is only available  with respect to  portfolios that are
registered for  sale  in  a  shareholder's  state  of  residence.  The  exchange
privilege  may be modified or  terminated by the Fund  at any time upon 60-days'
notice to shareholders.
    
 
BY MAIL
 
   
    In order to  exchange shares  by mail, you  should include  in the  exchange
request  the name, class of shares and account number of your current Portfolio,
the names of the portfolio(s) and class(es)  of shares into which you intend  to
exchange  shares, and the signatures of all registered account holders. Send the
exchange request  to Morgan  Stanley Institutional  Fund, Inc.,  P.O. Box  2798,
Boston, Massachusetts 02208-2798.
    
 
BY TELEPHONE
 
   
    When  exchanging shares by  telephone, have ready the  name, class of shares
and account number of  the current portfolios, the  name(s) of the  portfolio(s)
and  class(es) of shares into  which you intend to  exchange shares, your Social
Security number  or Tax  I.D. number,  and your  account address.  Requests  for
telephone  exchanges received prior to 4:00 p.m. (Eastern Time) are processed at
the close of business that same day based on the net asset value of the class of
the portfolio  involved in  the exchange  of shares  at the  close of  business.
Requests received after 4:00 p.m. (Eastern Time) are processed the next business
day  based on the  net asset value determined  at the close  of business on such
day. For additional information regarding responsibility for the authenticity of
telephoned instructions, see "Redemption of Shares By Telephone" above.
    
 
   
TRANSFER OF REGISTRATION
    
 
   
    You may transfer  the registration  of any of  your Fund  shares to  another
person  by writing  to Morgan Stanley  Institutional Fund, Inc.,  P.O. Box 2798,
Boston, Massachusetts 02208-2798.  As in  the case of  redemptions, the  written
request  must  be  received in  good  order  before any  transfer  can  be made.
Transferring the  registration of  shares  may affect  the eligibility  of  your
account  for  a  given  class  of  the  Portfolio's  shares  and  may  result in
involuntary conversion or redemption  of your shares.  See "Purchase of  Shares"
above.
    
 
                              VALUATION OF SHARES
 
   
    The  net asset  value per  share of a  class of  shares of  the Portfolio is
determined by dividing the total market value of the Portfolio's investments and
other assets attributable to  such class, less  any liabilities attributable  to
such  class, by  the total  number of  outstanding shares  of such  class of the
Portfolio. Net  asset value  is  calculated separately  for  each class  of  the
Portfolio.  Net asset value per  share is determined as  of the regular close of
the NYSE on each day  that the NYSE is open  for business. Price information  on
listed  securities is  taken from the  exchange where the  security is primarily
traded. Securities  listed  on  a  U.S. securities  exchange  for  which  market
quotations are available are valued at the last quoted sale price on the day the
valuation  is made. Securities listed on a  foreign exchange are valued at their
closing price.  Unlisted securities  and  listed securities  not traded  on  the
valuation  date for which market quotations are not readily available are valued
at a price within a  range not exceeding the current  asked price nor less  than
the  current bid price. The current bid and asked prices are determined based on
the bid and asked prices quoted on such valuation date by reputable brokers.
    
 
    Bonds and other fixed income securities are valued according to the broadest
and most representative  market, which will  ordinarily be the  over-the-counter
market.  Net asset value includes interest  on fixed income securities, which is
accrued daily.  In addition,  bonds and  other fixed  income securities  may  be
valued on the basis of prices provided by a pricing service when such prices are
believed to reflect the fair market value of such
 
                                       26
<PAGE>
securities.  The prices  provided by  a pricing  service are  determined without
regard to  bid or  last sale  prices but  take into  account institutional  size
trading  in similar  groups of  securities and  any developments  related to the
specific securities. Securities not priced in this manner are valued at the most
recently quoted bid price or, when  securities exchange valuations are used,  at
the  latest quoted  sale price  on the  day of  valuation. If  there is  no such
reported sale, the latest  quoted bid price will  be used. Securities  purchased
with remaining maturities of 60 days or less are valued at amortized cost, if it
approximates market value. In the event that amortized cost does not approximate
market value, market prices as determined above will be used.
 
    The value of other assets and securities for which no quotations are readily
available  (including  restricted  and unlisted  foreign  securities)  and those
securities for which it is inappropriate to determine prices in accordance  with
the  above-stated procedures  are determined in  good faith at  fair value using
methods determined by the  Board of Directors. For  purposes of calculating  net
asset value per share, all assets and liabilities initially expressed in foreign
currencies will be translated into U.S. dollars at the mean of the bid price and
asked  price of such currencies against the U.S. dollar last quoted by any major
bank.
 
    Although the legal rights of Class A  and Class B shares will be  identical,
the  different expenses borne by  each class will result  in different net asset
values and dividends for the class.  Dividends will differ by approximately  the
amount  of the distribution expense accrual  differential among the classes. The
net asset value of  Class B shares  will generally be lower  than the net  asset
value  of the Class A shares as a  result of the distribution expense charged to
Class B shares.
 
                            PERFORMANCE INFORMATION
 
   
    The Fund may from time  to time advertise "total  return" for each class  of
the  Portfolio.  THESE FIGURES  ARE  BASED ON  HISTORICAL  EARNINGS AND  ARE NOT
INTENDED TO  INDICATE  FUTURE PERFORMANCE.  The  "total return"  shows  what  an
investment in a class of the Portfolio would have earned over a specified period
of  time (such as  one, five or  ten years) assuming  that all distributions and
dividends by the portfolio were reinvested in the same class on the reinvestment
dates during the period. Total return does not take into account any federal  or
state  income taxes that  may be payable  on dividend and  distributions or upon
redemption. The Fund  may also  include comparative  performance information  in
advertising  or marketing a portfolio's shares. Such performance information may
include data from Lipper Analytical Services, Inc., other industry publications,
business periodicals, rating services and market indices.
    
 
   
    The performance figures  for Class  B shares  will generally  be lower  than
those  for Class  A shares because  of the  distribution fee charged  to Class B
shares.
    
 
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
 
   
    All income dividends and capital gains  distributions for a class of  shares
will automatically be reinvested in additional shares of such class at net asset
value,  except that,  upon written  notice to  the Fund  or by  checking off the
appropriate box in the Distribution  Option Section on the Account  Registration
Form,  a shareholder  may elect  to receive  income dividends  and capital gains
distributions in cash. The Portfolio expects to distribute substantially all  of
its  net  investment income  in the  form of  quarterly dividends.  Net realized
gains, if any,  after reduction for  any available tax  loss carryforwards  will
also  be distributed  annually. Confirmations of  the purchase of  shares of the
Portfolio through the  automatic reinvestment  of income  dividends and  capital
gains distributions
    
 
                                       27
<PAGE>
   
will  be provided, pursuant to Rule  10b-10(b) under the Securities Exchange Act
of 1934,  as  amended, on  the  next  monthly client  statement  following  such
purchase  of shares. Consequently,  confirmations of such  purchases will not be
provided at  the time  of completion  of such  purchases as  might otherwise  be
required by Rule 10b-10.
    
 
   
    Undistributed  net investment income is included in a portfolio's net assets
for the purpose  of calculating  net asset value  per share.  Therefore, on  the
"ex-dividend"  date, the net asset value  per share excludes the dividend (i.e.,
is reduced by  the per  share amount of  the dividend).  Dividends paid  shortly
after  the purchase  of shares by  an investor,  although in effect  a return of
capital, are taxable to shareholders subject to income tax.
    
 
   
    Because of  the  distribution  fee  and  any  other  expenses  that  may  be
attributable  to the  Class B  shares, the  net income  attributable to  and the
dividends payable  on  Class  B  shares  will  be  lower  than  the  net  income
attributable  to and the dividends  payable on Class A  shares. As a result, the
net asset value per share of the classes of the Portfolio will differ at  times.
Expenses of the Portfolio allocated to a particular class of shares thereof will
be borne on a pro rata basis by each outstanding share of that class.
    
 
                                     TAXES
 
   
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
    
 
   
    No  attempt has been made to present  a detailed explanation of the federal,
state, or  local income  tax treatment  of the  Portfolio or  its  shareholders.
Accordingly,  shareholders  are urged  to consult  their tax  advisors regarding
specific questions as to federal, state and local income taxes.
    
 
   
    The Portfolio  is  treated as  a  separate  entity for  federal  income  tax
purposes  and is  not combined with  the Fund's other  portfolios. The Portfolio
intends to qualify for the  special tax treatment afforded regulated  investment
companies  under Subchapter M of  the Internal Revenue Code  of 1986, as amended
(the "Code"), so that the  Portfolio will be relieved  of federal income tax  on
that  part of its net investment income and net capital gain that is distributed
to shareholders.
    
 
   
    The Portfolio distributes  substantially all  of its  net investment  income
(including,  for  this purpose,  net short-term  capital gain)  to shareholders.
Dividends from the Portfolio's net investment income are taxable to shareholders
as ordinary  income, whether  received in  cash or  in additional  shares.  Such
dividends  will generally qualify  for the 70%  dividends-received deduction for
corporate shareholders only to the  extent of the aggregate qualifying  dividend
income  received by  the Portfolio  from U.S.  corporations. The  Portfolio will
report annually to its shareholders the amount of dividend income qualifying for
such treatment.
    
 
   
    Distributions of net capital gain (the excess of net long-term capital  gain
over  net  short-term capital  loss) are  taxable  to shareholders  as long-term
capital gain, regardless of  how long shareholders have  held their shares.  The
Portfolio  sends  reports annually  to shareholders  of  the federal  income tax
status of all distributions made during the preceding year.
    
 
   
    The  Portfolio   intends  to   make  sufficient   distributions  or   deemed
distributions  of its ordinary income and capital gain net income (the excess of
short-term and long-term  capital gains  over short-term  and long-term  capital
losses), including any available capital loss carryforwards, prior to the end of
each calendar year to avoid liability for federal excise tax.
    
 
                                       28
<PAGE>
   
    Dividends  and  other distributions  declared by  the Portfolio  in October,
November or December of any year and payable to shareholders of record on a date
in such month will be deemed to have been paid by the Portfolio and received  by
the  shareholders on December 31  of that year if  the distributions are paid by
the Portfolio at any time during the following January.
    
 
   
    The sale, exchange  or redemption of  shares may result  in taxable gain  or
loss to the selling, exchanging or redeeming shareholder, depending upon whether
the  fair market value  of the redemption  proceeds exceeds or  is less than the
shareholder's adjusted  basis in  the  redeemed, exchanged  or sold  shares.  If
capital  gain distributions have been made with  respect to shares that are sold
at a loss after being held for six months or less, then the loss is treated as a
long-term capital loss to the extent of the capital gain distributions.
    
 
   
    The conversion of Class A shares to  Class B shares should not be a  taxable
event to the shareholder.
    
 
   
    Shareholders  are urged  to consult with  their tax  advisors concerning the
application of state  and local income  taxes to investments  in the  Portfolio,
which may differ from the federal income tax consequences described above.
    
 
   
    Investment  income  received by  the Portfolio  from sources  within foreign
countries may be subject to foreign income taxes withheld at the source. To  the
extent  that the Portfolio is  liable for foreign income  taxes so withheld, the
Portfolio intends to operate so as to meet the requirements of the Code to  pass
through  to the shareholders credit for  foreign income taxes paid. Although the
Portfolio intends to  meet Code  requirements to  pass through  credit for  such
taxes, there can be no assurance that the Portfolio will be able to do so.
    
 
   
    THE   TAX  DISCUSSION  SET  FORTH  ABOVE  IS  INCLUDED  HEREIN  FOR  GENERAL
INFORMATION ONLY. PROSPECTIVE  INVESTORS SHOULD CONSULT  THEIR OWN TAX  ADVISERS
WITH RESPECT TO THE TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN THE PORTFOLIO.
    
 
                             PORTFOLIO TRANSACTIONS
 
    The  Sub-Advisory  Agreement  authorizes  the  Sub-Adviser,  subject  to the
supervision of the Adviser, to select  the brokers or dealers that will  execute
the  purchases and sales of investment  securities for the Portfolio and directs
the Sub-Adviser to use its best efforts  to obtain the best available price  and
most favorable execution with respect to all transactions for the Portfolio. The
Fund  has authorized the Sub-Adviser to pay higher commissions in recognition of
brokerage services which, in the opinion  of the Sub-Adviser, are necessary  for
the  achievement of better  execution, provided the  Sub-Adviser, subject to the
supervision of the Adviser believes this to be in the best interest of the Fund.
 
    Since shares of the Portfolio are not marketed through intermediary  brokers
or  dealers, it is  not the Fund's  practice to allocate  brokerage or principal
business on the basis of sales of  shares which may be made through such  firms.
However,   the   Sub-Adviser   may  place   portfolio   orders   with  qualified
broker-dealers who recommend the Fund's Portfolios  or who act as agents in  the
purchase of shares of the Portfolios for their clients.
 
    In  purchasing and  selling securities for  the Portfolio, it  is the Fund's
policy to seek to obtain quality execution at the most favorable prices, through
responsible  broker-dealers.  In   selecting  broker-dealers   to  execute   the
securities  transactions for the Portfolio, consideration  will be given to such
factors as the price of the security,  the rate of the commission, the size  and
difficulty    of    the   order,    the   reliability,    integrity,   financial
 
                                       29
<PAGE>
condition,  general  execution   and  operational   capabilities  of   competing
broker-dealers,  and the brokerage  and research services  which they provide to
the Fund. Some securities considered for investment by the Portfolio may also be
appropriate for  other clients  served by  the Adviser  or the  Sub-Adviser.  If
purchase  or sale of  securities consistent with the  investment policies of the
Portfolio and  one or  more of  these other  clients served  by the  Adviser  or
Sub-Adviser  is  considered at  or  about the  same  time, transactions  in such
securities will be  allocated among the  Portfolio and such  other clients in  a
manner deemed fair and reasonable by the Sub-Adviser, subject to the supervision
of  the  Adviser. Although  there is  no specified  formula for  allocating such
transactions, the various allocation  methods used by  the Sub-Adviser, and  the
results  of such allocations, are subject to periodic review by the Fund's Board
of Directors.
 
    Subject to the overriding objective of obtaining the best possible execution
of orders,  the Sub-Adviser,  subject to  the supervision  of the  Adviser,  may
allocate  a portion of the Portfolio brokerage transactions to Morgan Stanley or
broker affiliates  of  Morgan  Stanley.  In order  for  Morgan  Stanley  or  its
affiliates  to effect any portfolio transactions  for the Fund, the commissions,
fees or other remuneration received by Morgan Stanley or such affiliates must be
reasonable and fair compared to the commissions, fees or other remuneration paid
to other brokers  in connection with  comparable transactions involving  similar
securities  being purchased or sold on a securities exchange during a comparable
period of time.  Furthermore, the Board  of Directors of  the Fund, including  a
majority  of the Directors who  are not "interested persons,"  as defined in the
Investment Company  Act of  1940,  as amended  (the  "1940 Act"),  have  adopted
procedures  which are reasonably designed to  provide that any commissions, fees
or other remuneration paid to Morgan  Stanley or such affiliates are  consistent
with the foregoing standard.
 
    Portfolio  securities will not be  purchased from or through,  or sold to or
through, the  Adviser, the  Sub-Adviser  or Morgan  Stanley or  any  "affiliated
persons,"  as defined in the 1940 Act,  of Morgan Stanley when such entities are
acting as principals, except to the extent permitted by law.
 
   
    Although the  Portfolio will  not invest  for short-term  trading  purposes,
investment securities may be sold from time to time without regard to the length
of  time  they have  been  held. The  Portfolio  anticipates that,  under normal
circumstances, the annual  portfolio turnover  rate will not  exceed 100%.  High
portfolio turnover involves correspondingly greater transaction costs which will
be  borne  directly by  the respective  Portfolio.  In addition,  high portfolio
turnover may  result  in  more capital  gains  which  would be  taxable  to  the
shareholders of the Portfolio.
    
 
                              GENERAL INFORMATION
 
DESCRIPTION OF COMMON STOCK
 
   
    The  Fund was  organized as  a Maryland  corporation on  June 16,  1988. The
Articles of Incorporation, as amended and restated, permit the Fund to issue  up
to  34 billion shares of common stock,  with $.001 par value per share. Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number of shares the  Fund is authorized  to issue without  the approval of  the
shareholders  of the  Fund. Subject  to the  notice period  to shareholders with
respect to shares held by shareholders, the Board of Directors has the power  to
designate  one or  more classes of  shares of  common stock and  to classify and
reclassify any unissued shares with
    
 
                                       30
<PAGE>
   
respect to  such classes.  The shares  of  common stock  of each  portfolio  are
currently  classified  into two  classes, the  Class  A shares  and the  Class B
shares, except for the International Small Cap, Money Market and Municipal Money
Market Portfolios, which only offer Class A shares.
    
 
   
    The shares of the Portfolio, when issued, will be fully paid, nonassessable,
fully transferable and redeemable at the  option of the holder. The shares  have
no  preference  as  to  conversion,  exchange,  dividends,  retirement  or other
features and  have  no preemptive  rights.  The  shares of  the  Portfolio  have
non-cumulative  voting rights, which means that the  holders of more than 50% of
the shares voting for the election of Directors can elect 100% of the  Directors
if  they choose  to do so.  Persons or organizations  owning 25% or  more of the
outstanding shares of a portfolio may be presumed to "control" (as that term  is
defined  in the 1940  Act) that Portfolio.  Under Maryland law,  the Fund is not
required to hold an annual meeting of its shareholders unless required to do  so
under the 1940 Act.
    
 
REPORTS TO SHAREHOLDERS
 
    The  Fund will send to its  shareholders annual and semi-annual reports; the
financial statements  appearing in  annual reports  are audited  by  independent
accountants.  Monthly unaudited portfolio  data is also  available from the Fund
upon request.
 
    In addition, the Adviser or its agent, as Transfer Agent, will send to  each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
 
CUSTODIAN
 
    As  of September  1, 1995  domestic securities and  cash are  held by Chase,
which replaced U.S.  Trust as  the Fund's domestic  custodian. Chase  is not  an
affiliate  of  the Adviser  or the  Distributor.  Morgan Stanley  Trust Company,
Brooklyn, New York, ("MSTC"), an affiliate  of the Adviser and the  Distributor,
acts  as the Fund's custodian for foreign  assets held outside the United States
and employs subcustodians  approved by  the Board of  Directors of  the Fund  in
accordance  with regulations of  the Securities and  Exchange Commission for the
purpose of providing  custodial services  for such  assets. MSTC  may also  hold
certain  domestic assets for  the Fund. For more  information on the custodians,
see "General Information -- Custody Arrangements" in the Statement of Additional
Information.
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
    Chase  Global   Funds  Services   Company,   73  Tremont   Street,   Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
 
INDEPENDENT ACCOUNTANTS
 
    Price  Waterhouse LLP  serves as  independent accountants  for the  Fund and
audits its annual financial statements.
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       31
<PAGE>
<TABLE>
<CAPTION>
            MORGAN STANLEY INSTITUTIONAL FUND, INC.
            GOLD PORTFOLIO
            P.O. BOX 2798, BOSTON, MA 02208-2798

- ---------------------------------------------------------------------------------------------------------------

                           ACCOUNT REGISTRATION FORM
- ---------------------------------------------------------------------------------------------------------------
<S>                        <C>
ACCOUNT INFORMATION        If you need assistance in filling out this form     
Fill in where applicable   for the Morgan Stanley Institutional Fund, please   
                           contact your Morgan Stanley representative or call  
                           us toll free 1-(800)-548-7786. Please print all     
                           items except signature, and mail to the Fund at the
                           address above.

- ---------------------------------------------------------------------------------------------------------------
A)  REGISTRATION
    1. INDIVIDUAL            1. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
                                 First Name           Initial              Last Name
    2. JOINT TENANTS         2. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       (RIGHTS OF                First Name           Initial              Last Name
       SURVIVORSHIP            / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       PRESUMED UNLESS           First Name           Initial              Last Name
       TENANCY IN COMMON 
       IS INDICATED)      
- ---------------------------------------------------------------------------------------------------------------
    3. CORPORATIONS,        3.  / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       TRUSTS AND OTHERS       
       Please call the          / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       Fund for additional
       documents that may       / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       be required to set 
       up account and to 
       authorize transactions.
                                Type of / / INCORPORATED / / UNINCORPORATED / / PARTNERSHIP / / UNIFORM GIFT/TRANSFER TO MINOR 
                                Registration:                 ASSOCIATION                   (ONLY ONE CUSTODIAN AND MINOR PERMITTED)


                                / / TRUST __________________________________     / / OTHER (Specify) ______________________________
- ---------------------------------------------------------------------------------------------------------------
B)  MAILING ADDRESS         Street or P.O. Box / / / / / / / / / / / / / / / / / / / / / / / / / / / /

    Please fill in 
    completely, including   City / / / / / / / / / / / / / State / / / Zip / / / / / /-/ / / / / / / / 
    telephone number(s).
                            Home                                   Business
                            Telephone No./ / / /-/ / / /-/ / / / / Telephone No./ / / /-/ / / /-/ / / /
                            / / United States  / / Resident  / /Non-Resident Alien:
                                Citizen            Alien        Indicate Country of Residence _________
- ---------------------------------------------------------------------------------------------------------------
C)  TAXPAYER                PART 1. Enter your Taxpayer         C) IMPORTANT TAX INFORMATION 
    IDENTIFICATION          Identification Number. For most          You (as a payee) are required by
    NUMBER                  individual taxpayers, this is your     law to provide us (as payer) with
    If the account is in    Social Security Number.                your correct Taxpayer Identification
    more than one name,     TAXPAYER IDENTIFICATION NUMBER         Number. Accounts that have a missing
    CIRCLE THE NAME OF THE    / / / /-/ / / / / / / / /            or incorrect Taxpayer Identification
    PERSON WHOSE TAXPAYER               OR                         Number will be subject to backup
    IDENTIFICATION NUMBER       SOCIAL SECURITY NUMBER             withholding at a 31% rate on dividends,
    IS PROVIDED IN SECTION    / / / /-/ / /-/ / / / /              distributions and other payments.
    A) ABOVE. If no name      PART 2. BACKUP WITHHOLDING           If you have not provided us with
    is circled, the number    / / Check this box if you are        your correct taxpayer identification
    will be considered to be  NOT subject to Backup                number, you may be subject to 
    that of the last name     Withholding under the                a $50 penalty imposed by the Internal
    listed. For Custodian     provisions of Section                Revenue Service.
    account of a minor        3406(a)(1)(C) of the Internal          Backup withholding is not an
    (Uniform Gift/Transfer    Revenue Code.                        additional tax; the tax liability of
    to Minor Act), give the                                        persons subject to backup withholding
    Social Security Number                                         will be reduced by the amount of tax
    of the minor.                                                  withheld. If withholding results in
                                                                   an overpayment of taxes, a refund 
                                                                   may be obtained. You may be notified
                                                                   that you are subject to backup 
                                                                   withholding under Section 3406(a)(1)(C)
                                                                   of the Internal Revenue Code because you
                                                                   have underreported interest or dividends
                                                                   or you were required to but failed to
                                                                   file a return which would have included a
                                                                   reportable interest or dividend payment. IF
                                                                   YOU HAVE NOT BEEN SO NOTIFIED, CHECK THE
                                                                   BOX IN PART 2 AT LEFT.
- ---------------------------------------------------------------------------------------------------------------
D)  PORTFOLIO AND          For Purchase of the following Portfolio:     
    CLASS SELECTION        Gold Portfolio                              / / Class A Shares $____ / / Class B Shares $____
    (Class A shares
    minimum $500,000
    for each Portfolio                                                      Total Initial Investment $_____________
    and Class B shares
    minimum $100,000 for
    each Portfolio).
    Please indicate
    class and amount.
- ---------------------------------------------------------------------------------------------------------------
   
E)  METHOD OF   Payment by:
    INVESTMENT  / / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND, INC.--GOLD PORTFOLIO)
    Please 
    indicate
    manner of   / / Exchange $____________ From________________       / / / / / / / / / / /-/ /
    payment.                                Name of Portfolio              Account No.

               / / Account previously established by: 

               / / Phone exchange / / Wire on___________________       / / / / / / / / / / / /-/ /
                                                          Date             Account No.            (Check
                                                                 (Previously assigned by the Fund) Digit)
    

<PAGE>
- ---------------------------------------------------------------------------------------------------------------

F)  DISTRIBUTION                                       Income dividends and capital gains distributions (if any) will
    OPTION                                             be reinvested in additional shares unless either box below is
                                                       checked.

                                                       / / Income dividends to be paid in cash, capital
                                                           gains distributions (if any) in shares.

                                                      / /  Income dividends and capital gains distributions
                                                           (if any) to be paid in cash.

- ---------------------------------------------------------------------------------------------------------------


G)  TELEPHONE                    / / I/we hereby authorize the Fund and its      ______________________   ________________
    REDEMPTION                       agents to honor any telephone requests      Name of COMMERCIAL Bank  Bank Account No.
    Please select at time of         to wire redemption proceeds to the            (Not Savings Bank)
    initial application if you       commercial bank indicated at rightand/or 
    wish to redeem shares by         mail redemption proceeds to the name and                             ________________
    telephone. A SIGNATURE           address in which my/our fund account is                                 Bank ABA No.
    GUARANTEE IS REQUIRED IF         registered if such requests are believed 
    BANK ACCOUNT IS NOT              to be authentic.                           _________________________________________________
    REGISTERED IDENTICALLY TO    The Fund and the Fund's Transfer Agent will    Name(s) in which your BANK Account is Established
    YOUR FUND ACCOUNT.           employ reasonable procedures to confirm that
                                 instructions communicated by telephone are     _________________________________________________
    TELEPHONE REQUESTS FOR       genuine. These procedures include requiring                 Bank's Street Address
    REDEMPTIONS WILL NOT BE      the investor to provide certain personal
    HONORED UNLESS THE BOX IS    identification information at the time an      _________________________________________________
    CHECKED.                     account is opened and prior to effecting each  City                    State                Zip
                                 transaction requested by telephone. In addition,
                                 all telephone transaction requests will be recorded
                                 and investors may be required to provide additional
                                 telecopied written instructions of transaction
                                 requests. Neither the Fund nor the Transfer Agent will
                                 be responsible for any loss, liability, cost or expense
                                 for following instructions received by telephone that
                                 it reasonably believes to be genuine.


- ---------------------------------------------------------------------------------------------------------------

H)  INTERESTED PARTY
    OPTION
    In addition to the account   _________________________________________________________________
    statement sent to my/our                                 Name
    registered address, I/we     _________________________________________________________________
    hereby authorize the fund    
    to mail duplicate            _________________________________________________________________
    statements to the name and                              Address
    address provided at right.
                                 _________________________________________________________________
                                  City                      State                     Zip Code

- ---------------------------------------------------------------------------------------------------------------

I)  DEALER 
    INFORMATION                  _______________________  _______________________________  ___________
                                 Representative Name          Representative No.             Branch No.

- ---------------------------------------------------------------------------------------------------------------

J)  SIGNATURE OF        The undersigned certify(ies)  that I/we  have full  authority and  legal
    ALL HOLDERS         capacity  to purchase and redeem shares of the Fund and affirm that I/we
    AND TAXPAYER        have received a current Prospectus  of the Morgan Stanley  Institutional
    CERTIFICATION       Fund,  Inc. and agree to  be bound by its  terms. UNDER THE PENALTIES OF
    Sign Here >         PERJURY, I/WE CERTIFY THAT THE INFORMATION PROVIDED IN SECTION C)
                        ABOVE IS TRUE, CORRECT AND COMPLETE.

                        (X)                                 (X)
                        __________________________________  ______________________________________
                        Signature                Date       Signature                  Date

- ---------------------------------------------------------------------------------------------------------------


</TABLE>
<PAGE>
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
 
  NO  DEALER, SALES  REPRESENTATIVE OR ANY  OTHER PERSON HAS  BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE  CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS  HAVING BEEN AUTHORIZED BY THE FUND  OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF  THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION  TO
ANY  PERSON TO WHOM  IT IS UNLAWFUL TO  MAKE SUCH OFFER  OR SOLICITATION IN SUCH
JURISDICTION.
                           --------------------------
 
                               TABLE OF CONTENTS
 
<TABLE>
<S>                                                 <C>
                                                    PAGE
                                                    ----
Fund Expenses.....................................    2
Financial Highlights..............................    4
Prospectus Summary................................    6
Investment Objective and Policies.................   10
Additional Investment Information.................   11
Investment Limitations............................   17
Management of the Fund............................   17
Purchase of Shares................................   20
Redemption of Shares..............................   24
Shareholder Services..............................   25
Valuation of Shares...............................   26
Performance Information...........................   27
Dividends and Capital Gains Distributions.........   27
Taxes.............................................   28
Portfolio Transactions............................   29
General Information...............................   30
Account Registration Form
</TABLE>
 
                                 GOLD PORTFOLIO
                               A PORTFOLIO OF THE
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
 
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Sub-Adviser
                            Sun Valley Gold Company
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
 
- ---------------------------------
- ---------------------------------
- ---------------------------------
- ---------------------------------
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
   -------------------------------------------------------------------------
 
                            GLOBAL EQUITY PORTFOLIO
                         INTERNATIONAL EQUITY PORTFOLIO
                       INTERNATIONAL SMALL CAP PORTFOLIO
                             ASIAN EQUITY PORTFOLIO
                           EUROPEAN EQUITY PORTFOLIO
                           JAPANESE EQUITY PORTFOLIO
                            LATIN AMERICAN PORTFOLIO
 
                               PORTFOLIOS OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
 
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
                                ----------------
 
   
    Morgan  Stanley Institutional Fund, Inc (the  "Fund") is a no-load, open-end
management investment company, or mutual fund, which offers redeemable shares in
a   series   of   diversified   and   non-diversified   investment    portfolios
("portfolios").   The  Fund   currently  consists   of  twenty-eight  portfolios
representing a  broad range  of  investment choices.  The  Fund is  designed  to
provide clients with attractive alternatives for meeting their investment needs.
This  prospectus (the  "Prospectus") pertains  to the  Class A  and the  Class B
shares of  the  Global  Equity, International  Equity,  Asian  Equity,  European
Equity,   Japanese  Equity  and  Latin   American  Portfolios  (the  "Multiclass
Portfolios") and to the Class A Shares of the International Small Cap  Portfolio
(collectively,  the "Portfolios"). On January 2, 1996, the Multiclass Portfolios
began offering two classes of shares, the Class A shares and the Class B shares,
except for the Money Market, Municipal Money Market and International Small  Cap
Portfolios  which only offer Class A shares.  All shares of the Portfolios owned
prior to January 2, 1996  were redesignated Class A  shares on January 2,  1996.
The International Equity Portfolio is currently closed to new investors with the
exception  of certain Morgan Stanley  customers. The Class A  and Class B shares
currently  offered  by   the  Portfolios  have   different  minimum   investment
requirements  and fund  expenses. Shares of  the portfolios are  offered with no
sales  charge  or  exchange  or  redemption  fee  (with  the  exception  of  the
International Small Cap Portfolio).
    
 
    The   GLOBAL  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
investing primarily  in  equity  securities of  issuers  throughout  the  world,
including U.S. issuers.
 
    The  INTERNATIONAL EQUITY PORTFOLIO seeks  long-term capital appreciation by
investing primarily in equity securities of non-U.S. issuers.
 
   
    The INTERNATIONAL SMALL CAP  PORTFOLIO seeks long-term capital  appreciation
by  investing primarily  in equity  securities of  non-U.S. issuers  with equity
market capitalizations of less than $1 billion.
    
 
    The ASIAN EQUITY PORTFOLIO seeks long-term capital appreciation by investing
primarily in equity securities of Asian issuers.
 
    The EUROPEAN  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
investing primarily in equity securities of European issuers.
 
    The  JAPANESE EQUITY PORTFOLIO seeks  long-term capital appreciation through
investment in equity securities of Japanese issuers.
 
    The  LATIN  AMERICAN  PORTFOLIO  seeks  long-term  capital  appreciation  by
investing  primarily in equity securities of  Latin American issuers and in debt
securities issued or  guaranteed by Latin  American governments or  governmental
entities.
 
    INVESTORS  SHOULD NOTE THAT EACH PORTFOLIO MAY INVEST UP TO 10% OF ITS TOTAL
ASSETS IN  RESTRICTED SECURITIES,  AND  THE INTERNATIONAL  SMALL CAP  AND  LATIN
AMERICAN  PORTFOLIOS MAY INVEST  UP TO 25%  OF THEIR RESPECTIVE  TOTAL ASSETS IN
RESTRICTED SECURITIES THAT ARE RULE 144A SECURITIES. SEE "ADDITIONAL  INVESTMENT
INFORMATION -- NON-PUBLICLY TRADED SECURITIES, PRIVATE PLACEMENTS AND RESTRICTED
SECURITIES."  INVESTMENTS  IN  RESTRICTED  SECURITIES  IN  EXCESS  OF  5%  OF  A
PORTFOLIO'S TOTAL ASSETS MAY BE  CONSIDERED A SPECULATIVE ACTIVITY, MAY  INVOLVE
GREATER RISK AND MAY INCREASE THE PORTFOLIO'S EXPENSES.
 
    The  Fund is designed  to meet the investment  needs of discerning investors
who place a premium on quality  and personal service. With Morgan Stanley  Asset
Management   Inc.  as   Adviser  and   Administrator  (the   "Adviser"  and  the
"Administrator"), and with Morgan Stanley & Co. Incorporated ("Morgan  Stanley")
as  Distributor, the  Fund makes available  to institutional and  high net worth
individual investors a series  of portfolios which  benefit from the  investment
expertise  and commitment to  excellence associated with  Morgan Stanley and its
affiliates.
 
   
    This Prospectus is designed to set forth concisely the information about the
Fund that a prospective investor should  know before investing and it should  be
retained  for future reference. The Fund  offers additional portfolios which are
described in other prospectuses and  under "Prospectus Summary" below. The  Fund
currently  offers the following portfolios:  (i) GLOBAL AND INTERNATIONAL EQUITY
- -- Active Country Allocation, Asian  Equity, Emerging Markets, European  Equity,
Global  Equity, Gold, International  Equity, International Magnum, International
Small Cap, Japanese Equity  and Latin American Portfolios;  (ii) U.S. EQUITY  --
Aggressive  Equity, Emerging  Growth, Equity  Growth, MicroCap,  Small Cap Value
Equity, U.S. Real  Estate and Value  Equity Portfolios; (iii)  EQUITY AND  FIXED
INCOME  -- Balanced Portfolio; (iv) FIXED INCOME -- Emerging Markets Debt, Fixed
Income,  Global  Fixed  Income,  High  Yield,  Mortgage-Backed  Securities   and
Municipal  Bond Portfolios; and  (v) MONEY MARKET --  Money Market and Municipal
Money Market Portfolios. Additional information about the Fund is contained in a
"Statement of Additional Information," dated May 1, 1996, which is  incorporated
herein   by  reference.  The   Statement  of  Additional   Information  and  the
prospectuses pertaining to the other portfolios  of the Fund are available  upon
request  and without charge  by writing or  calling the Fund  at the address and
telephone number set forth above.
    
 
 THESE SECURITIES  HAVE NOT  BEEN  APPROVED OR  DISAPPROVED BY  THE  SECURITIES
   AND  EXCHANGE COMMISSION OR  ANY STATE SECURITIES  COMMISSION, NOR HAS THE
    SECURITIES AND EXCHANGE  COMMISSION OR ANY  STATE SECURITIES  COMMISSION
     PASSED   UPON  THE  ACCURACY  OR  ADEQUACY  OF  THIS  PROSPECTUS.  ANY
             REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.
 
   
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1996.
    
<PAGE>
                                 FUND EXPENSES
 
    The  following table illustrates the expenses and fees that a shareholder of
each Portfolio listed below will incur.
   
<TABLE>
<CAPTION>
                                                GLOBAL EQUITY   INTERNATIONAL EQUITY   INTERNATIONAL SMALL    ASIAN EQUITY
SHAREHOLDER TRANSACTION EXPENSES                  PORTFOLIO           PORTFOLIO           CAP PORTFOLIO         PORTFOLIO
- ---------------------------------------------  ---------------  ---------------------  -------------------  -----------------
<S>                                            <C>              <C>                    <C>                  <C>
Maximum Sales Load Imposed on Purchases
  Class A....................................          None                None                  None*               None
  Class B....................................          None                None                  None*               None
Maximum Sales Load Imposed on Reinvested
 Dividends
  Class A....................................          None                None                  None                None
  Class B....................................          None                None                   N/A                None
Deferred Sales Load
  Class A....................................          None                None                  None                None
  Class B....................................          None                None                   N/A                None
Redemption Fees
  Class A....................................          None                None                  1.00%*              None
  Class B....................................          None                None                  1.00%*              None
Exchange Fees
  Class A....................................          None                None                  None                None
  Class B....................................          None                None                   N/A                None
 
<CAPTION>
 
                                                                   EUROPEAN EQUITY       JAPANESE EQUITY     LATIN AMERICAN
SHAREHOLDER TRANSACTION EXPENSES                                      PORTFOLIO             PORTFOLIO           PORTFOLIO
- ---------------------------------------------                   ---------------------  -------------------  -----------------
<S>                                            <C>              <C>                    <C>                  <C>
Maximum Sales Load Imposed on Purchases
  Class A.....................................................             None                  None                None
  Class B.....................................................             None                  None                None
Maximum Sales Load Imposed on Reinvested Dividends
  Class A.....................................................             None                  None                None
  Class B.....................................................             None                  None                None
Deferred Sales Load
  Class A.....................................................             None                  None                None
  Class B.....................................................             None                  None                None
Redemption Fees
  Class A.....................................................             None                  None                None
  Class B.....................................................             None                  None                None
Exchange Fees
  Class A.....................................................             None                  None                None
  Class B.....................................................             None                  None                None
</TABLE>
    
 
- --------------------------
* Shareholders of  the International  Small Cap  Portfolio are  charged a  1.00%
  transaction  fee, which  is payable  directly to  the International  Small Cap
  Portfolio, in connection with  each purchase and redemption  of shares of  the
  Portfolio.  The  transaction fee  is  intended to  allocate  transaction costs
  associated with  purchases  and redemptions  of  shares of  the  Portfolio  to
  investors  actually making such  purchases and redemptions  rather than to the
  Portfolio's  other  shareholders.  The  1.00%  fee  represents  the  Adviser's
  estimate  of such transaction costs, which  include the costs of acquiring and
  disposing of Portfolio securities. The transaction  fee is not a sales  charge
  or  load,  and  is  retained by  the  Portfolio.  The fee  does  not  apply to
  Portfolios of the Fund other than the International Small Cap Portfolio and is
  not charged in
 
                                       2
<PAGE>
  connection with the reinvestment of  dividends or capital gain  distributions.
  The  fee will not be charged with respect to purchases and redemptions that do
  not result in  actual transaction  costs to  the Portfolio.  Examples of  such
  transactions   include  offsetting  purchases  and  redemptions  by  different
  shareholders occurring at the same time and in-kind purchases and redemptions.
   
<TABLE>
<CAPTION>
                                                                    INTERNATIONAL
                                                  GLOBAL EQUITY        EQUITY         INTERNATIONAL SMALL   ASIAN EQUITY
ANNUAL FUND OPERATING EXPENSES                      PORTFOLIO         PORTFOLIO          CAP PORTFOLIO       PORTFOLIO
- ------------------------------------------------  -------------  -------------------  -------------------  --------------
 (AS A PERCENTAGE OF AVERAGE NET ASSETS)
<S>                                               <C>            <C>                  <C>                  <C>
Management Fee (Net of Fee Waivers)***
  Class A.......................................        0.67%             0.77%                0.86%              0.62%
  Class B.......................................        0.67%             0.77%                  N/A              0.62%
12b-1 Fees
  Class A.......................................         None              None                 None               None
  Class B.......................................        0.25%             0.25%                  N/A              0.25%
Other Expenses
  Class A.......................................        0.33%             0.23%                0.29%              0.38%
  Class B.......................................        0.33%             0.23%                  N/A              0.38%
                                                  -------------         -------              -------       --------------
Total Operating Expenses (Net of Fee Waivers)*
  Class A.......................................        1.00%             1.00%                1.15%              1.00%
  Class B.......................................        1.25%             1.25%                  N/A              1.25%
                                                  -------------         -------              -------       --------------
                                                  -------------         -------              -------       --------------
 
<CAPTION>
 
                                                                   EUROPEAN EQUITY      JAPANESE EQUITY    LATIN AMERICAN
ANNUAL FUND OPERATING EXPENSES                                        PORTFOLIO            PORTFOLIO         PORTFOLIO
- ------------------------------------------------                 -------------------  -------------------  --------------
 (AS A PERCENTAGE OF AVERAGE NET ASSETS)
<S>                                               <C>            <C>                  <C>                  <C>
Management Fee (Net of Fee Waivers)***
  Class A......................................................           0.55%                0.60%              0.00%
  Class B......................................................           0.55%                0.60%              0.00%
12b-1 Fees
  Class A......................................................            None                 None               None
  Class B......................................................           0.25%                0.25%              0.25%
Other Expenses
  Class A......................................................           0.45%                0.40%              1.70%**
  Class B......................................................           0.45%                0.40%              1.70%**
                                                                        -------              -------       --------------
Total Operating Expenses (Net of Fee Waivers)
  Class A......................................................           1.00%                1.00%              1.70%**
  Class B......................................................           1.25%                1.25%              1.95%**
                                                                        -------              -------       --------------
                                                                        -------
</TABLE>
    
 
- --------------------------
   
  * "Other Expenses" for the Latin American Portfolio includes an annual fee  of
    0.125%   of  the  Portfolios'  average  weekly  net  assets  paid  to  local
    administrators  required  under  Brazilian  and  Chilean  law.  See   "Local
    Administrators for the Latin American Portfolio".
    
 
   
 ** Annualized.
    
 
   
*** The  Adviser has agreed  to waive its management  fees and/or reimburse each
    Portfolio, if necessary, if  such fees would cause  any of the total  annual
    operating  expenses of  the Portfolios to  exceed a  specified percentage of
    their respective average daily net assets. Set forth
    
 
                                       3
<PAGE>
   
    below, for each Portfolio as applicable,  are the management fees and  total
    operating  expenses absent such fee waivers and/or expense reimbursements as
    a percent  of  average  daily net  assets  of  the Class  A  shares  of  the
    Portfolios and Class B Shares of the Multiclass Portfolios, respectively.
    
 
   
<TABLE>
<CAPTION>
                                                                                     TOTAL OPERATING EXPENSES
                                                                                        ABSENT FEE WAIVERS
                                                                     MANAGEMENT
                                                                  FEES ABSENT FEE   --------------------------
PORTFOLIO                                                             WAIVERS         CLASS A       CLASS B+
- ----------------------------------------------------------------  ----------------  ------------  ------------
<S>                                                               <C>               <C>           <C>
Global Equity...................................................          0.80%           1.13%         1.38%
International Equity............................................          0.80%           1.03%         1.28%
International Small Cap.........................................          0.95%           1.24%          N/A
Asian Equity....................................................          0.80%           1.18%         1.43%
European Equity.................................................          0.80%           1.25%         1.50%
Japanese Equity.................................................          0.80%           1.20%         1.45%
Latin American..................................................          1.10%           3.13%++       3.38%++
</TABLE>
    
 
- ------------------------------
   
 + Estimated.
    
 
   
++ Annualized.
    
   These  reductions became  effective as  of the  inception of  each Portfolio,
   except with respect to  the International Equity Portfolio,  as to which  the
   effective  date was February 15,  1990. As a result  of these reductions, the
   Management Fees stated above are lower than the contractual fees stated under
   "Management of  the Fund."  For  further information  on Fund  expenses,  see
   "Management of the Fund."
 
   
    The  purpose of  the table  is to assist  the investor  in understanding the
various expenses  that an  investor  in the  Portfolios  will bear  directly  or
indirectly.  The Class A  expenses and fees  for Portfolios are  based on actual
figures for the fiscal year  ended December 31, 1995.  The Class B expenses  and
fees  for the  Multiclass Portfolios  are based  on estimates  assuming that the
average daily net assets of the Class B shares of each Multiclass Portfolio will
be $50,000,000. "Other Expenses" include Board of Directors' fees and  expenses,
amortization  or organizational costs, filing  fees, professional fees and costs
for shareholder reports. Due to the  continuous nature of Rule 12b-1 fees,  long
term  Class  B shareholders  may pay  more  than the  equivalent of  the maximum
front-end sales charges otherwise permitted by the Rules of Fair Practice of the
National Association of Securities Dealers, Inc. ("NASD").
    
 
                                       4
<PAGE>
    The following  example illustrates  the expenses  that you  would pay  on  a
$1,000 investment assuming (1) a 5% rate of return and (2) redemption at the end
of  each time  period. As  noted above, the  only fee  charged by  the Fund upon
purchase or redemption  of Fund  shares is the  1% transaction  fee assessed  on
purchases  and redemptions of  shares of the  International Small Cap Portfolio,
which charges  are reflected  in this  example. The  example is  based on  total
operating expenses of the Portfolios after fee waivers.
 
   
<TABLE>
<CAPTION>
                                               3       5       10
                                     1 YEAR  YEARS   YEARS    YEARS
                                     ------  ------  ------  -------
<S>                                  <C>     <C>     <C>     <C>
Global Equity Portfolio
  Class A..........................  $  10   $  32   $  55   $  122
  Class B..........................     13      40      69      151
International Equity Portfolio
  Class A..........................     10      32      55      122
  Class B..........................     13      40      69      151
International Small Cap Portfolio
  Class A..........................     32      57      85      163
Asian Equity Portfolio
  Class A..........................     10      32      55      122
  Class B..........................     13      40      69      151
European Equity Portfolio
  Class A..........................     10      32      55      122
  Class B..........................     13      40      69      151
Japanese Equity Portfolio
  Class A..........................     10      32      55      122
  Class B..........................     13      40      69      151
Latin American Portfolio
  Class A..........................     17      54      92      201
  Class B..........................     20      61     105      227
</TABLE>
    
 
    THIS  EXAMPLE SHOULD  NOT BE CONSIDERED  A REPRESENTATION OF  PAST OR FUTURE
EXPENSES OR  PERFORMANCE. ACTUAL  EXPENSES MAY  BE GREATER  OR LESS  THAN  THOSE
SHOWN.
 
   
    The  Fund intends to  continue to comply  with all state  laws that restrict
investment company expenses. Currently, the most restrictive state law  requires
that the aggregate annual expenses of an investment company shall not exceed two
and  one-half percent (2 1/2%)  of the first $30  million of average net assets,
two percent (2%)  of the next  $70 million of  average net assets,  and one  and
one-half  percent  (1  1/2%) of  the  remaining  net assets  of  such investment
company.
    
 
    The Adviser has agreed to a reduction  in the amounts payable to it, and  to
reimburse  any Portfolio,  if necessary, if  in any  fiscal year the  sum of the
Portfolio's expenses exceeds the limit set by applicable state law.
 
                                       5
<PAGE>
                              FINANCIAL HIGHLIGHTS
 
   
    The following table provides financial highlights for the Class A shares  of
the  Portfolios  for  each  of  the  periods  presented.  The  audited financial
highlights for the Class A  shares for the fiscal  year ended December 31,  1995
are  part of the Fund's financial statements which appear in the Fund's December
31, 1995 Annual  Report to  Shareholders and which  are included  in the  Fund's
Statement  of Additional  Information. The Portfolios'  financial highlights for
each of the periods in the five years ended December 31, 1995 have been  audited
by  Price Waterhouse, LLP, whose unqualified  report thereon is also included in
the Statement of Additional Information. Additional performance information  for
the  Class A shares is included in the  Annual Report. The Annual Report and the
financial  statements   therein,  along   with  the   Statement  of   Additional
Information, are available at no cost from the Fund at the address and telephone
number  noted on the cover page of this Prospectus. Financial highlights are not
available for the new Class B shares since they were not offered as of  December
31,  1995. Subsequent to October 31, 1992 (the Fund's prior fiscal year end) the
Fund changed  its fiscal  year end  to December  31. The  following  information
should be read in conjunction with the financial statements and notes thereto.
    
 
                                       6
<PAGE>
                            GLOBAL EQUITY PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                   JULY 15,     TWO MONTHS
                                                   1992* TO        ENDED       YEAR ENDED     YEAR ENDED     YEAR ENDED
                                                  OCTOBER 31,  DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,
                                                     1992          1992           1993           1994           1995
                                                  -----------  -------------  -------------  -------------  -------------
<S>                                               <C>          <C>            <C>            <C>            <C>
NET ASSET VALUE, BEGINNING OF PERIOD............   $   10.00     $    9.35      $    9.75      $   13.87      $   13.40
                                                  -----------  -------------  -------------  -------------  -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)(2)..................        0.02          0.01           0.08           0.08           0.18
  Net Realized and Unrealized Gain/(Loss) on
   Investments..................................       (0.67)         0.39           4.18           0.79           2.26
                                                  -----------  -------------  -------------  -------------  -------------
  Total from Investment Operations..............       (0.65)         0.40           4.26           0.87           2.44
                                                  -----------  -------------  -------------  -------------  -------------
DISTRIBUTIONS
  Net Investment Income.........................          --            --          (0.02)         (0.12)         (0.22)
  In Excess of Net Investment Income............          --            --          (0.03)            --             --
  Net Realized Gain.............................          --            --          (0.09)         (1.22)         (1.31)
                                                  -----------  -------------  -------------  -------------  -------------
Total Distributions.............................          --            --          (0.14)         (1.34)         (1.53)
                                                  -----------  -------------  -------------  -------------  -------------
NET ASSET VALUE, END OF PERIOD..................   $    9.35     $    9.75      $   13.87      $   13.40      $   14.31
                                                  -----------  -------------  -------------  -------------  -------------
                                                  -----------  -------------  -------------  -------------  -------------
TOTAL RETURN....................................       (6.50)%        4.28%         44.24%          6.95%         18.66%
                                                  -----------  -------------  -------------  -------------  -------------
                                                  -----------  -------------  -------------  -------------  -------------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)...........   $  11,257     $  11,739      $  19,918      $  78,935      $  91,675
Ratio of Expenses to Average Net Assets
 (1)(2).........................................        1.00%**        1.00%**        1.00%         1.00%          1.00%
Ratio of Net Investment Income to Average Net
 Assets (1).....................................        1.00%**        0.69%**        0.84%         0.87%          1.17%
Portfolio Turnover Rate.........................          10%            5%            42%            12%            28%
</TABLE>
    
 
- ------------------------------
 
   
<TABLE>
<S> <C>                                                 <C>         <C>         <C>         <C>         <C>
(1) Effect of voluntary expense limitation during the period:
    Per share benefit to net investment income........  $  0.08     $  0.02     $  0.01     $  0.02     $  0.02
    Ratios before expense limitation:
    Expenses to Average Net Assets....................     5.22%**     2.49%**     1.66%       1.24%       1.13%
    Net Investment Income (Loss) to Average
       Net Assets.....................................    (3.22)%**   (0.80)%**    0.18%       0.63%       1.04%
</TABLE>
    
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to  receive a management  fee calculated at  an annual rate  of 0.80% of the
    average daily net  assets of the  Global Equity Portfolio.  The Adviser  has
    agreed  to waive  a portion  of this  fee and/or  reimburse expenses  of the
    Portfolio to the extent that the  total operating expenses of the  Portfolio
    exceed 1.00% of the average daily net assets of the Class A shares and 1.25%
    of  the average daily net assets of the Class B shares. In the fiscal period
    ended October 31,  1992, the  two months ended  December 31,  1992, and  the
    years  ended December 31, 1993, 1994 and 1995, the Adviser waived management
    fees  and/or  reimbursed  expenses  totalling  $97,000,  $28,000,  $101,000,
    $126,000 and $109,000, respectively, for the Global Equity Portfolio.
    
 
 * Commencement of Operations.
 
** Annualized.
 
                                       7
<PAGE>
                         INTERNATIONAL EQUITY PORTFOLIO
   
<TABLE>
<CAPTION>
                                                                                                             TWO
                                                      AUGUST 4,                                            MONTHS        YEAR
                                                      1989* TO       YEAR         YEAR         YEAR         ENDED        ENDED
                                                        OCTO-     ENDED OCTO-  ENDED OCTO-  ENDED OCTO-    DECEM-       DECEM-
                                                       BER 31,      BER 31,      BER 31,      BER 31,      BER 31,      BER 31,
                                                        1989         1990         1991         1992         1992         1993
                                                     -----------  -----------  -----------  -----------  -----------  -----------
<S>                                                  <C>          <C>          <C>          <C>          <C>          <C>
NET ASSET VALUE, BEGINNING OF PERIOD...............   $   10.00    $    9.72    $   10.05    $   10.52    $    9.83    $    9.98
                                                     -----------  -----------  -----------  -----------  -----------  -----------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income............................        0.05         0.19         0.12         0.12         0.01         0.15
  Net Realized and Unrealized Gain/(Loss) on
   Investments.....................................       (0.33)        0.20         0.58        (0.59)        0.14         4.36
                                                     -----------  -----------  -----------  -----------  -----------  -----------
  Total from Investment Operations.................       (0.28)        0.39         0.70        (0.47)        0.15         4.51
                                                     -----------  -----------  -----------  -----------  -----------  -----------
DISTRIBUTIONS
  Net Investment Income............................          --        (0.06)       (0.15)       (0.17)          --        (0.01)
  In Excess of Net Investment Income...............          --           --           --           --           --        (0.13)
  Net Realized Gain................................          --           --        (0.08)       (0.05)          --        (0.26)
                                                     -----------  -----------  -----------  -----------  -----------  -----------
Total Distributions................................          --        (0.06)       (0.23)       (0.22)          --        (0.40)
                                                     -----------  -----------  -----------  -----------  -----------  -----------
NET ASSET VALUE, END OF PERIOD.....................   $    9.72    $   10.05    $   10.52    $    9.83    $    9.98    $   14.09
                                                     -----------  -----------  -----------  -----------  -----------  -----------
                                                     -----------  -----------  -----------  -----------  -----------  -----------
TOTAL RETURN.......................................       (2.80)%       3.99%        7.17%       (4.56)%       1.53%       46.50%
                                                     -----------  -----------  -----------  -----------  -----------  -----------
                                                     -----------  -----------  -----------  -----------  -----------  -----------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)..............   $   7,811    $ 110,716    $ 283,776    $ 486,836    $ 510,727    $ 947,045
Ratio of Expenses to Average Net
 Assets (1)(2).....................................        1.35%**       1.03%       1.00%        1.00%        1.00%**       1.00%
Ratio of Net Investment Income to Average Net
 Assets (1)(2).....................................        2.34%        3.51%        2.27%        1.46%        0.68%**       1.25%
Portfolio Turnover Rate............................           0%          38%          22%          12%           5%          23%
 
<CAPTION>
 
                                                         YEAR          YEAR
                                                     ENDED DECEM-  ENDED DECEM-
                                                       BER 31,       BER 31,
                                                         1994          1995
                                                     ------------  ------------
<S>                                                  <C>           <C>
NET ASSET VALUE, BEGINNING OF PERIOD...............   $    14.09    $    15.34
                                                     ------------  ------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income............................         0.16          0.16
  Net Realized and Unrealized Gain/(Loss) on
   Investments.....................................         1.54          1.55
                                                     ------------  ------------
  Total from Investment Operations.................         1.70          1.71
                                                     ------------  ------------
DISTRIBUTIONS
  Net Investment Income............................        (0.18)        (0.06)
  In Excess of Net Investment Income...............           --            --
  Net Realized Gain................................        (0.27)        (1.84)
                                                     ------------  ------------
Total Distributions................................        (0.45)        (1.90)
                                                     ------------  ------------
NET ASSET VALUE, END OF PERIOD.....................   $    15.34    $    15.15
                                                     ------------  ------------
                                                     ------------  ------------
TOTAL RETURN.......................................        12.39%        11.77%
                                                     ------------  ------------
                                                     ------------  ------------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)..............   $1,304,770    $1,598,503
Ratio of Expenses to Average Net
 Assets (1)(2).....................................         1.00%         1.00%
Ratio of Net Investment Income to Average Net
 Assets (1)(2).....................................         1.12%         1.38%
Portfolio Turnover Rate............................           16%           27%
</TABLE>
    
 
- ------------------------
   
<TABLE>
<S>                                           <C>          <C>          <C>          <C>          <C>          <C>
(1) Effect of voluntary expense limitation during the period:
      Per share benefit to net investment
       income...............................   $    0.00+   $    0.01    $    0.01    $    0.00+   $    0.00+   $    0.01
   Ratios before expense limitation:
      Expenses to Average Net Assets........        2.58%**       1.24%       1.09%        1.02%        1.14%**       1.06%
      Net Investment Income to Average Net
       Assets...............................        1.11%**       3.30%       2.18%        1.44%        0.54%**       1.19%
 
<CAPTION>
(1) Effect of voluntary expense limitation d
<S>                                           <C>          <C>
      Per share benefit to net investment
       income...............................   $   0.004    $   0.003
   Ratios before expense limitation:
      Expenses to Average Net Assets........        1.03%        1.03%
      Net Investment Income to Average Net
       Assets...............................        1.09%        1.35%
</TABLE>
    
 
   
 + Per share benefit to net investment income is less than $0.0001.
    
 
   
(2)Under  the terms of an Investment Advisory Agreement, the Adviser is entitled
   to receive a  management fee calculated  at an  annual rate of  0.80% of  the
   average  daily net assets of the  International Equity Portfolio. The Adviser
   has agreed to waive a  portion of this fee  and/or reimburse expenses of  the
   Portfolio  to the extent  that the total operating  expenses of the Portfolio
   exceed 1.00% of the average daily net assets of the Class A shares and  1.25%
   of  the average  daily net assets  of the Class  B shares. In  the year ended
   October 31,  1991, the  year ended  October 31,  1992, the  two months  ended
   December  31, 1992, and the years ended December 31, 1993, 1994 and 1995, the
   Adviser waived management fees and/or reimbursed expenses totaling  $147,000,
   $78,000,  $116,000, $405,000,  $344,000 and  $424,000, respectively,  for the
   International Equity Portfolio.
    
 
 * Commencement of Operations.
 
** Annualized.
 
                                       8
<PAGE>
                       INTERNATIONAL SMALL CAP PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                               DECEMBER 15,
                                                 1992* TO       YEAR ENDED      YEAR ENDED      YEAR ENDED
                                               DECEMBER 31,    DECEMBER 31,    DECEMBER 31,    DECEMBER 31,
                                                   1992            1993+           1994            1995
                                               -------------   -------------   -------------   -------------
<S>                                            <C>             <C>             <C>             <C>
NET ASSET VALUE, BEGINNING OF PERIOD.........  $   10.00       $   10.09       $   14.64       $   15.15
                                                  ------       -------------   -------------   -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)(3)...............       0.01            0.09            0.14            0.24
  Net Realized and Unrealized Gain on
   Investments (2)...........................       0.08            4.48            0.62            0.15
                                                  ------       -------------   -------------   -------------
  Total from Investment Operations...........       0.09            4.57            0.76            0.39
                                                  ------       -------------   -------------   -------------
DISTRIBUTIONS
  Net Investment Income......................         --            0.00           (0.03)          (0.23)
  In Excess of Net Investment Income.........         --           (0.02)             --              --
  Net Realized Gain..........................         --              --           (0.22)          (0.37)
Total Distributions..........................         --           (0.02)          (0.25)          (0.60)
                                                  ------       -------------   -------------   -------------
NET ASSET VALUE, END OF PERIOD                 $   10.09       $   14.64       $   15.15       $   14.94
                                                  ------       -------------   -------------   -------------
                                                  ------       -------------   -------------   -------------
TOTAL RETURN.................................       0.90%          45.34%           5.25%           2.60%
                                                  ------       -------------   -------------   -------------
                                                  ------       -------------   -------------   -------------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)........  $   3,824       $  52,834       $ 160,101       $ 198,669
Ratio of Expenses to Average Net Assets
 (1)(3)......................................       1.15%**         1.15%           1.15%           1.15%
Ratio of Net Investment Income to
 Average Net Assets (1)(3)...................       1.37%**         0.66%           1.18%           1.72%
Portfolio Turnover Rate......................          0%             14%              8%             24%
</TABLE>
    
 
- ------------------------------
 
   
<TABLE>
<S> <C>                                        <C>             <C>             <C>             <C>
(1) Effect of voluntary expense limitation during the
     period:
    Per share benefit to net investment
     income..................................  $    0.16       $    0.10       $    0.02       $    0.01
    Ratios before expense limitation:
    Expenses to Average Net Assets...........      21.67%**         1.86%           1.29%           1.24%
    Net Investment Income/(Loss) to Average
     Net Assets..............................     (19.15)%**       (0.05)%          1.04%           1.63%
</TABLE>
    
 
   
(2) Includes a  1%  transaction fee  on  purchases and  redemptions  of  capital
    shares.
    
 
   
(3) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to  receive a management  fee calculated at  an annual rate  of 0.95% of the
    average daily net assets of the Class A shares of the Portfolio. The Adviser
    has agreed to waive a portion of  this fee and/or reimburse expenses of  the
    Portfolio  to the extent that the  total operating expenses of the Portfolio
    exceed 1.15% of the average  daily net assets of the  Class A shares of  the
    Portfolio.  In  the period  ended  December 31,  1992,  and the  years ended
    December 31, 1993, 1994 and 1995, the Adviser waived management fees  and/or
    reimbursed  expenses  totaling  $32,000,  $151,000,  $174,000  and $181,000,
    respectively, for the International Small Cap Portfolio.
    
 
 * Commencement of Operations.
 
** Annualized.
 
 + Per share amounts for the year ended  December 31, 1993 are based on  average
   outstanding shares.
 
                                       9
<PAGE>
                             ASIAN EQUITY PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                          TWO
                                                JULY 1,      YEAR       MONTHS       YEAR        YEAR        YEAR
                                               1991, TO      ENDED       ENDED       ENDED       ENDED       ENDED
                                                OCTOBER     OCTOBER    DECEMBER    DECEMBER    DECEMBER    DECEMBER
                                               31, 1991    31, 1992    31, 1992    31, 1993    31, 1994    31, 1995
                                               ---------   ---------   ---------   ---------   ---------   ---------
<S>                                            <C>         <C>         <C>         <C>         <C>         <C>
NET ASSET VALUE, BEGINNING OF PERIOD.........  $ 10.00     $  9.67     $ 13.63     $ 13.11     $ 26.20     $ 21.54
                                               ---------   ---------   ---------   ---------   ---------   ---------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)(2)...............     0.03        0.14        0.01        0.10        0.11        0.18
  Net Realized and Unrealized Gain/(Loss) on
   Investments...............................    (0.36)       3.86       (0.53)      13.38       (4.15)       1.11
                                               ---------   ---------   ---------   ---------   ---------   ---------
  Total from Investment Operations...........   (0.33)        4.00      (0.52)       13.48      (4.04)        1.29
                                               ---------   ---------   ---------   ---------   ---------   ---------
DISTRIBUTIONS
  Net Investment Income......................       --       (0.04)         --       (0.01)      (0.09)      (0.34)
  In Excess of Net Investment Income.........       --          --          --       (0.13)         --       (0.00)+
  Net Realized Gain..........................       --          --          --       (0.12)      (0.53)      (3.01)
  In Excess of Net Realized Gain.............       --          --          --       (0.13)         --          --
                                               ---------   ---------   ---------   ---------   ---------   ---------
Total Distributions..........................       --       (0.04)         --       (0.39)      (0.62)      (3.35)
                                               ---------   ---------   ---------   ---------   ---------   ---------
NET ASSET VALUE, END OF PERIOD...............  $  9.67     $ 13.63     $ 13.11     $ 26.20     $ 21.54     $ 19.48
                                               ---------   ---------   ---------   ---------   ---------   ---------
                                               ---------   ---------   ---------   ---------   ---------   ---------
TOTAL RETURN.................................    (3.30)%     41.50%      (3.82)%    105.71%     (15.81)%      6.87%
                                               ---------   ---------   ---------   ---------   ---------   ---------
                                               ---------   ---------   ---------   ---------   ---------   ---------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)........  $10,719     $41,017     $41,978     $287,136    $276,906    $314,884
Ratio of Expenses to Average Net Assets
 (1)(2)......................................     1.00%**     1.00%       1.00%**     1.00%       1.00%       1.00%
Ratio of Net Investment Income to Average Net
 Assets (1)(2)...............................     1.13%**     1.53%       0.61%**     0.83%       0.52%       0.97%
Portfolio Turnover Rate......................        2%         33%         10%         18%         47%         42%
</TABLE>
    
 
- ------------------------------
 
   
<TABLE>
<S> <C>                                        <C>         <C>         <C>         <C>         <C>         <C>
(1) Effect of voluntary expense limitation during the period:
    Per share benefit to net
       investment income.....................  $  0.02     $  0.06     $  0.02     $  0.05     $  0.04     $  0.03
    Ratios before expense limitation:
    Expenses to Average Net Assets...........     2.52%**     1.63%       2.02%**     1.38%       1.20%       1.18%
    Net Investment Income/(Loss)
       to Average Net Assets.................    (0.39)%**    0.90%      (0.41)%**    0.45%       0.32%       0.79%
</TABLE>
    
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to  receive a management  fee calculated at  an annual rate  of 0.80% of the
    average daily net  assets of  the Asian  Equity Portfolio.  The Adviser  has
    agreed  to waive  a portion  of this  fee and/or  reimburse expenses  of the
    Portfolio to the extent that the  total operating expenses of the  Portfolio
    exceed 1.00% of the average daily net assets of the Class A shares and 1.25%
    of  the average daily net assets of the Class B shares. In the fiscal period
    ended October 31,  1991, the  year ended October  31, 1992,  the two  months
    ended  December 31, 1992,  and the years  ended December 31,  1993, 1994 and
    1995, the Adviser waived management fees and/or reimbursed expenses totaling
    $44,000, $167,000, $70,000, $477,000,  $535,000 and $522,000,  respectively,
    for the Asian Equity Portfolio.
    
 
   
 * Commencement of Operations.
    
 
   
** Annualized.
    
 
   
 + Amount is less than $0.01 per share.
    
 
                                       10
<PAGE>
                           EUROPEAN EQUITY PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                 APRIL 2,
                                                 1993* TO       YEAR ENDED      YEAR ENDED
                                               DECEMBER 31,    DECEMBER 31,    DECEMBER 31,
                                                   1993            1994            1995
                                               -------------   -------------   -------------
<S>                                            <C>             <C>             <C>
NET ASSET VALUE, BEGINNING OF PERIOD.........  $   10.00       $   12.91       $   13.94
                                               -------------   -------------   -------------
                                               -------------   -------------   -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)(2)...............       0.08            0.08            0.14
  Net Realized and Unrealized Gain on
   Investments...............................       2.83            1.29            1.37
                                               -------------   -------------   -------------
  Total from Investment Operations...........       2.91            1.37            1.51
                                               -------------   -------------   -------------
DISTRIBUTIONS
  Net Investment Income......................         --           (0.09)          (0.15)
  Net Realized Gain..........................         --           (0.25)          (1.38)
                                               -------------   -------------   -------------
Total Distributions..........................         --           (0.34)          (1.53)
                                               -------------   -------------   -------------
NET ASSET VALUE, END OF PERIOD...............  $   12.91       $   13.94       $   13.92
                                               -------------   -------------   -------------
                                               -------------   -------------   -------------
TOTAL RETURN.................................      29.10%          10.88%          11.85%
                                               -------------   -------------   -------------
                                               -------------   -------------   -------------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)........  $  12,681       $  27,634       $  69,583
Ratio of Expenses to Average Net Assets
 (1)(2)......................................       1.00%**         1.00%           1.00%
Ratio of Net Investment Income to Average Net
 Assets (1)(2)...............................       1.23%**         0.87%           1.37%
Portfolio Turnover Rate......................         15%             79%             13%
</TABLE>
    
 
- ------------------------------
 
   
<TABLE>
<S> <C>                                        <C>             <C>             <C>
(1) Effect of voluntary expense limitation during the
     period:
    Per share benefit to net investment
     income..................................  $    0.09       $    0.06       $    0.03
    Ratios before expense limitation:
    Expenses to Average Net Assets...........       2.43%**         1.62%           1.25%
    Net Investment Income/(Loss) to Average
     Net Assets..............................      (0.21)%**        0.25%           1.12%
</TABLE>
    
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to  receive a management  fee calculated at  an annual rate  of 0.80% of the
    average daily net assets of the  European Equity Portfolio. The Adviser  has
    agreed  to waive  a portion  of this  fee and/or  reimburse expenses  of the
    Portfolio to the extent that the  total operating expenses of the  Portfolio
    exceed 1.00% of the average daily net assets of the Class A shares and 1.25%
    of  the average daily net assets of the Class B shares. In the fiscal period
    ended December 31, 1993, 1994 and  1995, the Adviser waived management  fees
    and/or   reimbursed  expenses  totaling   $88,000,  $112,000  and  $130,000,
    respectively, for the European Equity Portfolio.
    
 
 * Commencement of Operations.
 
** Annualized.
 
                                       11
<PAGE>
                           JAPANESE EQUITY PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                PERIOD FROM
                                                 APRIL 25,
                                                 1994* TO       YEAR ENDED
                                               DECEMBER 31,    DECEMBER 31,
                                                   1994            1995
                                               -------------   -------------
<S>                                            <C>             <C>
NET ASSET VALUE, BEGINNING OF PERIOD.........  $   10.00       $    9.83
                                               -------------   -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (Loss) (1)...........      (0.01)           0.04
  Net Realized and Unrealized Loss on
   Investments+..............................      (0.16)          (0.40)
                                               -------------   -------------
  Total from Investment Operations...........      (0.17)          (0.36)
                                               -------------   -------------
DISTRIBUTIONS
  In Excess of Net Investment Income.........         --           (0.20)
                                               -------------   -------------
NET ASSET VALUE, END OF PERIOD...............  $    9.83       $    9.27
                                               -------------   -------------
                                               -------------   -------------
TOTAL RETURN.................................      (1.70)%         (3.64)%
                                               -------------   -------------
                                               -------------   -------------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)........  $  50,332       $ 119,278
Ratio of Expenses to Average Net Assets
 (1)(2)......................................       1.00%**         1.00%
Ratio of Net Investment Income (Loss) to
 Average Net Assets (1)(2)...................      (0.10)%**        0.15%
Portfolio Turnover Rate......................          1%             52%
</TABLE>
    
 
- ------------------------
 
   
<TABLE>
<S> <C>                                        <C>             <C>
(1) Effect of voluntary expense limitation during the period:
    Per share benefit to net investment
     income..................................  $    0.02       $    0.06
    Ratios before expense limitation:
    Expenses to Average Net Assets...........       1.27%**         1.20%
    Net Investment Loss to Average Net
     Assets..................................      (0.37)%**       (0.05)%
</TABLE>
    
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to receive a management  fee calculated at  an annual rate  of 0.80% of  the
    average  daily net assets of the  Japanese Equity Portfolio. The Adviser has
    agreed to  waive a  portion of  this fee  and/or reimburse  expenses of  the
    Portfolio  to the extent that the  total operating expenses of the Portfolio
    exceed 1.00% of the average daily net assets of the Class A shares and 1.25%
    of the average daily net assets of the Class B shares. In the fiscal  period
    ended  December 31, 1994 and 1995, the Adviser waived management fees and/or
    reimbursed expenses  totaling $80,000  and $118,000,  respectively, for  the
    Japanese Equity Portfolio.
    
 
   
 * Commencement of Operations.
    
 
   
** Annualized.
    
 
   
 + The amount shown for the year ended December 31, 1995 for a share outstanding
   throughout  the year does not accord  with aggregate net gains on investments
   for the year because of the timing of sales and repurchases of the  Portfolio
   shares  in relation  to fluctuating  market value  of the  investments in the
   Portfolio.
    
 
                                       12
<PAGE>
                            LATIN AMERICAN PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                               PERIOD FROM JANUARY
                                                  18, 1995* TO
                                                DECEMBER 31, 1995
                                               -------------------
<S>                                            <C>
NET ASSET VALUE, BEGINNING OF PERIOD.........  $         10.00
                                                       -------
                                                       -------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)..................             0.05
  Net Realized and Unrealized Loss on
   Investments...............................            (0.92)
                                                       -------
  Total from Investment Operations...........            (0.87)
                                                       -------
DISTRIBUTIONS
  Net Investment Income......................            (0.04)
  Return of Capital..........................            (0.03)
                                                       -------
Total Distributions..........................            (0.07)
                                                       -------
NET ASSET VALUE, END OF PERIOD...............  $          9.06
                                                       -------
                                                       -------
TOTAL RETURN.................................            (8.68)%
                                                       -------
                                                       -------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)........  $        15,376
Ratio of Expenses to Average Net Assets
 (1)(2)......................................             1.70%**
Ratio of Net Investment Income to Average Net
 Assets (1)(2)...............................             0.62%**
Portfolio Turnover Rate......................              137%
</TABLE>
    
 
- ------------------------
 
   
<TABLE>
<S> <C>                                        <C>
(1) Effect of voluntary expense limitation during the period:
    Per share benefit to net investment
     income..................................  $          0.09
    Ratios before expense limitation:
    Expenses to Average Net Assets...........             3.13%**
    Net Investment Loss to Average Net
     Assets..................................            (0.48)%**
</TABLE>
    
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to receive a management  fee calculated at  an annual rate  of 1.10% of  the
    average  daily net assets  of the Latin American  Portfolio. The Adviser has
    agreed to  waive a  portion of  this fee  and/or reimburse  expenses of  the
    Portfolio  to the extent that the  total operating expenses of the Portfolio
    exceed 1.70% of the average daily net assets of the Class A shares and 1.95%
    of the average daily net assets of the Class B shares. In the fiscal  period
    ended   December  31,  1995,  the  Adviser  waived  management  fees  and/or
    reimbursed expenses totalling $146,000 for the Portfolio.
    
 
 * Commencement of Operations.
 
** Annualized.
 
                                       13
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
 
   
    The   Fund  consists  of  twenty-eight  portfolios,  offering  institutional
investors and high net  worth individual investors a  broad range of  investment
choices coupled with the advantages of a no-load mutual fund with Morgan Stanley
and  its affiliates providing customized  services as Adviser, Administrator and
Distributor.  Each  portfolio  offers  Class  A  shares  and,  except  for   the
International  Small Cap,  Money Market  and Municipal  Money Market Portfolios,
also offers Class B shares. Each portfolio has its own investment objective  and
policies  designed to meet its specific  goals. The investment objective of each
Portfolio described in this Prospectus is as follows:
    
 
    -The  GLOBAL  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing  primarily in equity securities  of issuers throughout the world,
     including U.S. issuers.
 
    -The INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation  by
     investing primarily in equity securities of non-U.S. issuers.
 
   
    -The  INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital appreciation
     by investing primarily in equity securities of non-U.S. issuers with equity
     market capitalizations of less than $1 billion.
    
 
    -The  ASIAN  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation   by
     investing primarily in equity securities of Asian issuers.
 
    -The  EUROPEAN  EQUITY  PORTFOLIO seeks  long-term  capital  appreciation by
     investing primarily in equity securities of European issuers.
 
    -The JAPANESE  EQUITY  PORTFOLIO seeks  long  term capital  appreciation  by
     investing primarily in equity securities of Japanese issuers.
 
    -The  LATIN  AMERICAN  PORTFOLIO  seeks  long-term  capital  appreciation by
     investing primarily in equity securities of Latin American issuers and debt
     securities  issued  or   guaranteed  by  Latin   American  governments   or
     governmental entities.
 
    The  other portfolios of the Fund  are described in other Prospectuses which
may be obtained from the Fund at the address and phone number noted on the cover
page of this  Prospectus. The objectives  of these other  portfolios are  listed
below:
 
    GLOBAL AND INTERNATIONAL EQUITY:
 
    -The   ACTIVE   COUNTRY   ALLOCATION  PORTFOLIO   seeks   long-term  capital
     appreciation by investing in accordance with country weightings  determined
     by  the  Adviser in  equity securities  of non-U.S.  issuers which,  in the
     aggregate, replicate broad country indices.
 
    -The CHINA GROWTH PORTFOLIO seeks to provide long-term capital  appreciation
     by  investing primarily  in equity  securities of  issuers in  The People's
     Republic of China, Hong Kong and Taiwan.
 
    -The EMERGING  MARKETS PORTFOLIO  seeks  long-term capital  appreciation  by
     investing primarily in equity securities of emerging country issuers.
 
   
    -The  INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation by
     investing primarily in equity securities of non-U.S. issuers in  accordance
     with EAFE country (as defined in "Investment Objective and Policies" below)
     weightings determined by the Adviser.
    
 
                                       14
<PAGE>
    -The  GOLD  PORTFOLIO  seeks  long-term  capital  appreciation  by investing
     primarily in equity securities of  foreign and domestic issuers engaged  in
     gold-related activities.
 
    U.S. EQUITY:
 
    -The  AGGRESSIVE EQUITY  PORTFOLIO seeks  capital appreciation  by investing
     primarily in corporate equity and equity-linked securities.
 
    -The EMERGING  GROWTH  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing  primarily  in  growth-oriented equity  securities  of  small- to
     medium-sized corporations.
 
    -The  EQUITY  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing  in  growth-oriented  equity securities  of  large capitalization
     companies.
 
    -The MICROCAP PORTFOLIO  seeks long-term capital  appreciation by  investing
     primarily in growth-oriented equity securities of small corporations.
 
    -The  SMALL CAP VALUE EQUITY PORTFOLIO  seeks high long-term total return by
     investing in  undervalued  equity  securities  of  small-  to  medium-sized
     companies.
 
    -The  U.S.  REAL ESTATE  PORTFOLIO seeks  to  provide above  average current
     income and long-term capital appreciation by investing primarily in  equity
     securities  of companies in  the U.S. real  estate industry, including real
     estate investment trusts.
 
    -The VALUE EQUITY PORTFOLIO seeks high  total return by investing in  equity
     securities  which the  Adviser believes to  be undervalued  relative to the
     stock market in general at the time of purchase.
 
    EQUITY AND FIXED INCOME:
 
    -The BALANCED PORTFOLIO seeks high total return while preserving capital  by
     investing  in  a combination  of  undervalued equity  securities  and fixed
     income securities.
 
    FIXED INCOME:
 
    -The EMERGING MARKETS DEBT  PORTFOLIO seeks high  total return by  investing
     primarily   in  debt  securities   of  government,  government-related  and
     corporate issuers located in emerging countries.
 
    -The FIXED INCOME PORTFOLIO seeks to produce a high total return  consistent
     with the preservation of capital by investing in a diversified portfolio of
     fixed income securities.
 
    -The  GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real rate
     of return while preserving capital by investing in fixed income  securities
     of issuers throughout the world, including U.S. issuers.
 
    -The  HIGH YIELD PORTFOLIO seeks to maximize  total return by investing in a
     diversified portfolio of high  yield fixed income  securities that offer  a
     yield  above  that  generally available  on  debt securities  in  the three
     highest rating categories of the recognized rating services.
 
    -The MORTGAGE-BACKED SECURITIES PORTFOLIO seeks  to produce as high a  level
     of  current income  as is  consistent with  the preservation  of capital by
     investing primarily  in  a  variety  of  investment  grade  mortgage-backed
     securities.
 
    -The  MUNICIPAL  BOND PORTFOLIO  seeks to  produce a  high level  of current
     income  consistent  with  preservation  of  principal  through   investment
     primarily  in municipal obligations,  the interest on  which is exempt from
     federal income tax.
 
                                       15
<PAGE>
    MONEY MARKET:
 
    -The MONEY MARKET PORTFOLIO  seeks to maximize  current income and  preserve
     capital  while maintaining  high levels  of liquidity  through investing in
     high quality money market instruments with remaining maturities of one year
     or less.
 
    -The MUNICIPAL MONEY MARKET PORTFOLIO  seeks to maximize current  tax-exempt
     income  and  preserve capital  while maintaining  high levels  of liquidity
     through investing in high quality  money market instruments with  remaining
     maturities of one year or less which are exempt from federal income tax.
 
INVESTMENT MANAGEMENT
 
   
    Morgan  Stanley Asset Management  Inc., a wholly  owned subsidiary of Morgan
Stanley Group  Inc.,  which,  together  with  its  affiliated  asset  management
companies,  at December 31, 1995 had approximately $57.4 billion in assets under
management as  an  investment  manager  or  as  a  fiduciary  adviser,  acts  as
investment  adviser to the Fund  and each of its  portfolios. See "Management of
the Fund -- Investment Adviser" and "Management of the Fund -- Administrator."
    
 
   
HOW TO INVEST
    
 
   
    Class A shares of  each Portfolio are offered  directly to investors at  net
asset  value with no sales commission or  12b-1 charges. Class B shares, offered
only by the Multiclass Portfolios, are offered at net asset value with no  sales
commission,  but with a  12b-1 fee, which  is accrued daily  and paid quarterly,
equal to 0.25% of the Class B shares' average daily net assets on an  annualized
basis.  Share purchases may be made by  sending investments directly to the Fund
or through  the Distributor.  Shares  in a  Portfolio  account opened  prior  to
January  2,  1996 were  designated  Class A  shares on  January  2, 1996.  For a
Multiclass Portfolio  account  opened  on  or after  January  2,  1996  (a  "New
Multiclass  Account"), the  minimum initial investment  is $500,000  for Class A
shares of each  Multiclass Portfolio  and $100,000 for  Class B  shares of  each
Multiclass  Portfolio. The International Equity Portfolio is currently closed to
new investors  with  the exception  of  certain Morgan  Stanley  customers.  The
minimum  initial investment  for Class A  shares of the  International Small Cap
Portfolio is $500,000. Certain exceptions to the foregoing minimums apply to (1)
shares in a Multiclass Portfolio account opened prior to January 2, 1996  (each,
a  "Pre-1996 Multiclass Account") with  a value of $100,000  or more on March 1,
1996 (a  "Grandfathered  Class  A  Account"); (2)  Portfolio  accounts  held  by
officers  of the Adviser and  its affiliates; and (3)  certain advisory or asset
allocation accounts, such as Total Funds Management accounts, managed by  Morgan
Stanley  or  its affiliates,  including  the Adviser  ("Managed  Accounts"). The
Adviser reserves the  right in its  sole discretion to  determine which of  such
advisory or asset allocation accounts shall be Managed Accounts. For information
regarding   Managed  Accounts,  please  contact   your  Morgan  Stanley  account
representative or the Fund at the telephone number provided on the cover of this
Prospectus. Shares in a  Pre-1996 Multiclass Account with  a value of less  than
$100,000 on March 1, 1996 (a "Grandfathered Class B Account") converted to Class
B  shares on March 1,  1996. The minimum investment levels  may be waived at the
discretion of the  Adviser for  (i) certain  employees and  customers of  Morgan
Stanley  or  its affiliates  and  certain trust  departments,  brokers, dealers,
agents, financial  planners, financial  services firms,  or investment  advisers
that  have entered into an agreement with  Morgan Stanley or its affiliates; and
(ii) retirement and  deferred compensation plans  and trusts used  to fund  such
plans, including, but not limited to, those defined in Section 401(a), 403(b) or
457  of the Internal Revenue  Code of 1986, as  amended, and "rabbi trusts." See
"Purchase of Shares  -- Minimum  Investment and Account  Sizes; Conversion  from
Class A to Class B Shares."
    
 
                                       16
<PAGE>
    The  minimum  subsequent investment  for  each Portfolio  account  is $1,000
(except for automatic reinvestment of dividends and capital gains  distributions
for  which there is no minimum). Such  subsequent investments will be applied to
purchase additional  shares  in  the same  class  held  by a  shareholder  in  a
Portfolio account. See "Purchase of Shares -- Additional Investments."
 
HOW TO REDEEM
 
    Class  A  shares of  each Portfolio  or  Class B  shares of  each Multiclass
Portfolio may be redeemed at any time, without cost, at the net asset value  per
share  of shares of  the applicable class  next determined after  receipt of the
redemption request. The redemption price may  be more or less than the  purchase
price.  Certain  redemptions  may  cause  involuntary  redemption  or  automatic
conversion. Class  A or  Class B  shares  held in  New Multiclass  Accounts  are
subject  to involuntary redemption  if shareholder redemption(s)  of such shares
reduces the value of such account to less than $100,000 for a continuous  60-day
period. Involuntary redemption does not apply to Managed Accounts, Grandfathered
Class  A Accounts and Grandfathered Class B Accounts, regardless of the value of
such accounts. Class A shares in a New Multiclass Account will convert to  Class
B  shares if shareholder redemption(s) of such  shares reduces the value of such
account to less than $500,000 for a continuous 60-day period. Class B shares  in
a New Multiclass Account will convert to Class A shares if shareholder purchases
of  additional Class B shares or market activity  cause the value of the Class B
shares in the  New Multiclass  Account to  increase to  $500,000 or  more. If  a
shareholder  reduces its total investment in Class A shares of the International
Small Cap Portfolio  to less  than $500,000, the  investment may  be subject  to
redemption.  See "Purchase  of Shares --  Minimum Account  Sizes and Involuntary
Redemption of Shares" and "Redemption of Shares."
 
RISK FACTORS
 
   
    The investment policies of each of  the Portfolios entail certain risks  and
considerations  of which an investor should be aware. Each Portfolio will invest
in securities  of  foreign issuers,  which  are  subject to  certain  risks  not
typically  associated  with domestic  securities.  The Latin  American Portfolio
invests in securities of  issuers located in  developing countries and  emerging
markets. These securities may impose greater liquidity risks and other risks not
typically  associated  with investing  in  more established  markets.  The Latin
American Portfolio may invest up to 20% of its total assets in lower rated  debt
securities  ("junk  bonds"),  including  sovereign  debt,  which  securities are
considered speculative with  regard to  the payment  of interest  and return  of
principal.  See "Investment Objectives and  Policies" and "Additional Investment
Information." In addition, each Portfolio  may invest in repurchase  agreements,
lend  its portfolio  securities, purchase securities  on a  when-issued basis or
delayed  delivery  basis  and  invest  in  forward  foreign  currency   exchange
contracts,  and  the Latin  American Portfolio  may  invest in  foreign currency
exchange options to hedge currency  risk associated with investment in  non-U.S.
dollar  denominated  securities.  Each  Portfolio may  invest  in  short-term or
medium-term debt  securities or  hold  cash or  cash equivalents  for  temporary
defensive  purposes.  The  International  Small  Cap  Portfolio  may  invest  in
securities  that   are  neither   listed  on   a  stock   exchange  nor   traded
over-the-counter,  including  private placement  securities. The  Global Equity,
Japanese Equity,  Latin American  and Asian  Equity Portfolios  may also  invest
indirectly  in securities  through sponsored or  unsponsored American Depositary
Receipts. Each of these investment strategies involves specific risks which  are
described  under "Investment Objectives and Policies" and "Additional Investment
Information" herein  and  under  "Investment Objectives  and  Policies"  in  the
Statement of Additional Information.
    
 
                                       17
<PAGE>
                       INVESTMENT OBJECTIVES AND POLICIES
 
    The investment objective of each Portfolio is described below, together with
the  policies the Fund employs in its  efforts to achieve these objectives. Each
Portfolio's investment  objective  is a  fundamental  policy which  may  not  be
changed without the approval of a majority of the Portfolio's outstanding voting
securities.  There is no assurance that the Fund will attain its objectives. The
investment policies  described below  are not  fundamental policies  and may  be
changed without shareholder approval.
 
THE GLOBAL EQUITY PORTFOLIO
 
    The   Global  Equity  Portfolio  seeks  long-term  capital  appreciation  by
investing primarily  in  equity  securities of  issuers  throughout  the  world,
including U.S. issuers. With respect to the Portfolio, equity securities include
common  and preferred stocks, convertible securities, and rights and warrants to
purchase common stocks. The Adviser expects that, under normal circumstances, at
least 20% of the Portfolio's total assets will be invested in the common  stocks
of  U.S. issuers.  The remainder  of the Portfolio  will be  invested in issuers
located throughout the world,  including those located  in emerging markets.  At
least  65%  of the  total assets  of the  Portfolio will  be invested  in equity
securities under normal circumstances. Securities in emerging markets may not be
as liquid as  those in developed  markets and pose  greater risks. Although  the
Portfolio  intends to invest primarily in  securities listed on stock exchanges,
it will  also  invest in  securities  traded in  over-the-counter  markets.  The
Adviser's orientation to individual stock selection and value driven approach in
selecting  investments for the Portfolio are the same as those described for the
International Equity  Portfolio discussed  below. The  Portfolio may  invest  in
American, Global or other types of Depositary Receipts.
 
    Although  the  Portfolio will  not invest  for short-term  trading purposes,
investment securities may be sold from time to time without regard to the length
of time they have been held. It is anticipated that the annual turnover rate  of
the Portfolio will not exceed 100% under normal circumstances.
 
    Any remaining assets of the Portfolio not invested as described above may be
invested  in  certain  securities or  obligations  as set  forth  in "Additional
Investment Information" below.
 
THE INTERNATIONAL EQUITY PORTFOLIO
 
    The investment objective of the International Equity Portfolio is to provide
long-term  capital  appreciation.  The  production  of  any  current  income  is
incidental  to this objective.  The Portfolio seeks to  achieve its objective by
investing primarily in equity  securities of non-U.S.  issuers. With respect  to
the   Portfolio,  equity   securities  include  common   and  preferred  stocks,
convertible securities, and rights  and warrants to  purchase common stocks.  At
least  65% of the total assets of the  Portfolio will be invested in such equity
securities under normal circumstances.
 
    The Adviser's  approach  in  selecting  investments  for  the  Portfolio  is
oriented to individual stock selection, and is value driven. In selecting stocks
for  the  Portfolio,  the Adviser  initially  identifies those  stocks  which it
believes to  be undervalued  in  relation to  the  issuer's assets,  cash  flow,
earnings  and revenues, and  then evaluates the  future value of  such stocks by
running the  results of  an in-depth  study  of the  issuer through  a  dividend
discount  model.  The Adviser  utilizes  the research  of  a number  of sources,
including  its  affiliate  in   Geneva,  Switzerland,  Morgan  Stanley   Capital
International,  in identifying  attractive securities,  and applies  a number of
 
                                       18
<PAGE>
proprietary screening criteria to  identify those securities  it believes to  be
undervalued.   Portfolio  holdings  are  regularly  reviewed  and  subjected  to
fundamental analysis  to  determine whether  they  continue to  conform  to  the
Adviser's  value  criteria. Securities  which no  longer  conform to  such value
criteria are sold.
 
    While  the   Portfolio   is  not   subject   to  any   specific   geographic
diversification  requirements,  it  currently intends  to  diversify investments
among countries to reduce currency risk.  Investments will be made primarily  in
equity securities of companies domiciled in developed countries, but may also be
made  in equity  securities of  companies domiciled  in developing  countries as
well. Although the Portfolio  intends to invest  primarily in equity  securities
listed  on stock exchanges, it  will also invest in  equity securities traded in
over-the-counter markets. Securities  of companies in  developing countries  may
pose liquidity risks. The Portfolio will not, under normal circumstances, invest
in   equity  securities   of  U.S.  issuers.   For  a   description  of  special
considerations and certain risks associated with investments in foreign issuers,
see "Additional Investment  Information." The Portfolio  may temporarily  reduce
its  equity  holdings  for  defensive purposes  in  response  to  adverse market
conditions and  invest  in domestic,  Eurodollar  and foreign  short-term  money
market instruments. See "Investment Objectives and Policies" in the Statement of
Additional Information.
 
    Although  the  Portfolio will  not invest  for short-term  trading purposes,
investment securities may be sold from time to time without regard to the length
of time they have been held. It is anticipated that the annual turnover rate  of
the Portfolio will not exceed 100% under normal circumstances.
 
    Any remaining assets of the Portfolio not invested as described above may be
invested  in  certain  securities or  obligations  as set  forth  in "Additional
Investment Information" below.
 
THE INTERNATIONAL SMALL CAP PORTFOLIO
 
   
    The investment  objective of  the International  Small Cap  Portfolio is  to
provide  long-term capital appreciation. The production of any current income is
incidental to this objective.  The Portfolio seeks to  achieve its objective  by
investing  primarily in equity securities of non-U.S. issuers with equity market
capitalizations of less than $1 billion.  With respect to the Portfolio,  equity
securities  include  common and  preferred  stocks, convertible  securities, and
rights and warrants to purchase common stocks. At least 65% of the total  assets
of  the  Portfolio  will be  invested  in  such equity  securities  under normal
circumstances. The Portfolio will invest a minimum of 80% of its total assets in
companies with market capitalizations of less  than $500 million and may  invest
up  to an  additional 20%  of its  total assets  in companies  with total market
capitalizations up to a maximum of $1 billion, for which the actual market float
as represented by the value  of the securities that  may be freely traded  falls
below  $500 million. The Adviser's orientation to individual stock selection and
value driven approach in selecting investments for the Portfolio are the same as
those described for the International Equity Portfolio discussed above.
    
 
    While  the   Portfolio   is  not   subject   to  any   specific   geographic
diversification  requirements,  it  currently intends  to  diversify investments
among countries to reduce currency risk.  Investments will be made primarily  in
equity  securities of  companies domiciled  in developed  countries, but limited
investments may  also  be made  in  the  securities of  companies  domiciled  in
developing  countries as  well, and  will not  normally exceed  5% of  the total
assets of the Portfolio. Although the  Portfolio intends to invest primarily  in
equity  securities  listed on  stock  exchanges, it  may  also invest  in equity
securities traded in over-the-counter  markets. Small capitalization  securities
involve  greater issuer  risk and  the markets for  such securities  may be more
volatile and less liquid.  Securities of companies  in developing countries  may
pose    liquidity    risks.    The   Portfolio    will    not,    under   normal
 
                                       19
<PAGE>
circumstances, invest in equity securities of U.S. issuers. For a description of
special considerations and certain risks associated with investments in  foreign
issuers,  see "Additional Investment Information." The Portfolio may temporarily
reduce its equity holdings for defensive purposes in response to adverse  market
conditions  and  invest in  domestic,  Eurodollar and  foreign  short-term money
market instruments. See "Investment Objectives and Policies" in the Statement of
Additional Information.
 
    Although the  Portfolio will  not invest  for short-term  trading  purposes,
investment securities may be sold from time to time without regard to the length
of  time they have been held. It is anticipated that the annual turnover rate of
the Portfolio will not exceed 100% under normal circumstances.
 
    Any remaining assets of the Portfolio not invested as described above may be
invested in  certain  securities or  obligations  as set  forth  in  "Additional
Investment Information" below.
 
THE ASIAN EQUITY PORTFOLIO
 
   
    The  investment  objective  of  the Asian  Equity  Portfolio  is  to provide
long-term  capital  appreciation.  The  production  of  any  current  income  is
incidental  to this objective.  The Portfolio seeks to  achieve its objective by
investing primarily in equity  securities which are  traded on recognized  stock
exchanges  of the countries in Asia described  below and in equity securities of
companies organized  under  the laws  of  an  Asian country  whose  business  is
conducted principally in Asia. The Portfolio does not intend to invest in equity
securities  which are  principally traded  in markets  in Japan  or in companies
organized under the  laws of Japan.  The Portfolio may  also invest in  American
Depositary  Receipts of Asian issuers that are  traded on stock exchanges in the
U.S.
    
 
    The Asian countries to  be represented in the  Portfolio, which include  the
following countries, have the more established markets in the region: Hong Kong,
Singapore,  Malaysia, Thailand, the Philippines and Indonesia. The Portfolio may
also invest in common  stocks traded on markets  in Taiwan, South Korea,  India,
Pakistan,  Sri  Lanka and  other  developing markets  that  are open  to foreign
investment. There is no requirement that the Fund, at any given time, invest  in
any  or all of the  countries listed above or in  any other Asian countries. The
Fund has  no set  policy  for allocating  investments  among the  various  Asian
countries.  Allocation of investments will depend on the relative attractiveness
of the stocks of issuers in the respective countries. Government regulation  and
restrictions in many of the countries of interest may limit the amount, mode and
extent of investment in companies of such countries.
 
    At least 65% of the total assets of the Portfolio will be invested in common
stocks  of Asian countries under normal  circumstances. The remaining portion of
the Fund will be kept in any combination of debt instruments, bills and bonds of
governmental entities in Asia and the  U.S., in notes, debentures, and bonds  of
companies  in Asia and in  money market instruments of  the U.S. With respect to
the  Portfolio,  equity   securities  include  common   and  preferred   stocks,
convertible securities, and rights and warrants to purchase common stocks.
 
    The  Adviser's orientation  to individual  stock selection  and value driven
approach in  selecting  investments  for  the Portfolio  are  similar  to  those
described  for the International  Equity Portfolio discussed  above. The Adviser
will analyze assets, revenues and earnings of an issuer. In selecting industries
and particular  issuers,  the Adviser  will  evaluate  costs of  labor  and  raw
materials,  access to technology, export  of products and government regulation.
Although the Portfolio  seeks to invest  in larger companies,  it may invest  in
medium  and  small companies  that, in  the Adviser's  view, have  potential for
growth.
 
                                       20
<PAGE>
    The Portfolio's investments  will include securities  of issuers located  in
developing  countries  and traded  in  emerging markets.  These  securities pose
greater liquidity risks and other risks than securities of companies located  in
developed countries and traded in more established markets. For a description of
special  considerations and certain risks  associated with investment in foreign
issuers, see "Additional Investment Information -- Foreign Investment." See also
"Investment Objectives and Policies" in the Statement of Additional Information.
 
    Although the  Portfolio intends  to invest  primarily in  equity  securities
listed  on stock exchanges, it  will also invest in  equity securities traded in
over-the-counter markets.  Securities traded  in over-the-counter  markets  pose
liquidity  risks. The Portfolio  may also invest in  initial public offerings in
the form of oversubscriptions or private placements. Such investments  generally
entail short-term liquidity risks.
 
    Although  the  Portfolio will  not invest  for short-term  trading purposes,
investment securities may be sold from time to time without regard to the length
of time they have been held. It is anticipated that the annual turnover rate  of
the Portfolio will not exceed 100% under normal circumstances.
 
    Pending  investment or settlement, and for liquidity purposes, the Portfolio
may  invest  in  domestic,  Eurodollar  and  foreign  short-term  money   market
instruments.  The Portfolio  may also  purchase such  instruments to temporarily
reduce its equity holdings for defensive purposes in response to adverse  market
conditions.
 
    Because  of the lack of hedging facilities  in the currency markets of Asia,
no active  currency hedging  strategy is  anticipated currently.  Instead,  each
investment  will be considered on a total  currency adjusted basis with the U.S.
dollar as  a  base currency.  The  Portfolio  may engage  in  currency  exchange
contracts.  See "Statement of Additional Information -- Forward Foreign Currency
Exchange Contracts" in this Prospectus.
 
    Any remaining assets of the Portfolio not invested as described above may be
invested in  certain  securities or  obligations  as set  forth  in  "Additional
Investment Information" below.
 
THE EUROPEAN EQUITY PORTFOLIO
 
    The  investment objective  of the  European Equity  Portfolio is  to provide
long-term capital appreciation. The Portfolio seeks to achieve this objective by
investing primarily in  equity securities of  European issuers, including  those
located  in  Germany,  France,  Switzerland,  Belgium,  Italy,  Finland, Sweden,
Denmark, Norway and the United Kingdom.  Investments may also be made in  equity
securities  of issuers  located in the  smaller and emerging  markets of Europe.
With respect to the  Portfolio, equity securities  include common and  preferred
stocks,  convertible  securities, and  rights  and warrants  to  purchase common
stocks. At least 65% of  the total assets of the  Portfolio will be invested  in
equity  securities of European issuers under normal circumstances. The Adviser's
orientation to individual stock selection and value-driven approach in selecting
investments  for  the  Portfolio  are  the  same  as  those  described  for  the
International  Equity Portfolio discussed above.  Securities in emerging markets
may not be  as liquid  as those  in developed  markets and  pose greater  risks.
Although  the Portfolio intends to invest  primarily in equity securities listed
on stock  exchanges,  it  will  also  invest  in  equity  securities  traded  in
over-the-counter markets.
 
    While   the   Portfolio  is   not   subject  to   any   specific  geographic
diversification requirements,  it  currently intends  to  diversify  investments
among  countries to reduce  currency risk. Investments may  be made primarily in
equity securities of companies domiciled in developed countries, but may also be
made in  equity securities  of companies  domiciled in  developing countries  as
well.    Although    the   Portfolio    intends    to   invest    primarily   in
 
                                       21
<PAGE>
equity securities listed on stock exchanges,  it will also invest in  securities
traded  in  over-the-counter  markets.  Securities  of  companies  in developing
countries may  pose  liquidity  risks.  The Portfolio  will  not,  under  normal
circumstances, invest in equity securities of U.S. issuers. For a description of
special  considerations and certain risks associated with investments in foreign
issuers, see "Additional Investment Information." The Portfolio may  temporarily
reduce  its equity holdings for defensive purposes in response to adverse market
conditions and  invest  in domestic,  Eurodollar  and foreign  short-term  money
market instruments. See "Investment Objectives and Policies" in the Statement of
Additional Information.
 
    Although  the  Portfolio will  not invest  for short-term  trading purposes,
investment securities may be sold from time to time without regard to the length
of time they have been held. It is anticipated that the annual turnover rate  of
the Portfolio will not exceed 100% under normal circumstances.
 
    Any remaining assets of the Portfolio not invested as described above may be
invested  in  certain  securities or  obligations  as set  forth  in "Additional
Investment Information" below.
 
THE JAPANESE EQUITY PORTFOLIO
 
    The investment  objective of  the Japanese  Equity Portfolio  is to  provide
long-term capital appreciation. The Portfolio seeks to achieve this objective by
investing  primarily in equity  securities of Japanese  issuers. With respect to
the  Portfolio,  equity   securities  include  common   and  preferred   stocks,
convertible securities, and rights and warrants to purchase common stocks.
 
   
    Under normal conditions, the Portfolio will invest at least 80% of its total
assets  in securities issued  by entities that  are organized under  the laws of
Japan, affiliates  of Japanese  companies (wherever  organized or  traded),  and
issuers  not organized under the laws of Japan but deriving 50% or more of their
revenues from Japan. These securities may include debt securities (issued by the
Japanese government or by Japanese companies) when the Adviser believes that the
potential for capital appreciation from investment in debt securities equals  or
exceeds   that  available  from  investment  in  equity  securities.  In  making
investment decisions, the Adviser will  consider, among other factors, the  size
of  the company, its financial condition,  its marketing and technical strengths
and its  competitiveness in  its  industry. All  debt  securities in  which  the
Portfolio  may  invest will  be rated  no lower  than BBB  by Standard  & Poor's
Ratings Group ("S&P"), Baa by Moody's Investors Service, Inc. ("Moody's") or BBB
by Mikuni  Inc.  ("Mikuni")  (a  Japanese rating  agency)  or,  if  unrated,  of
comparable  quality as determined  by the Adviser. Securities  rated BBB by S&P,
Baa by Moody's or BBB by Mikuni have speculative characteristics and changes  in
economic conditions or other circumstances are more likely to lead to a weakened
capacity  to make principal and interest  payments on such securities than would
be the case with  higher rated securities. The  convertible securities in  which
the  Portfolio may invest include bonds, notes, debentures, preferred stocks and
other securities convertible into common stocks and may be fixed-income or  zero
coupon  debt securities. Prior  to their conversion,  convertible securities may
have characteristics similar to nonconvertible debt securities.
    
 
    The Portfolio  currently  intends  to  focus  its  investments  in  Japanese
companies  that have  an active  market for  their shares  and that  the Adviser
believes show  a  potential  for  better  than  average  growth.  The  Portfolio
anticipates  that  most  equity securities  of  Japanese companies  in  which it
invests, either directly or indirectly by means of American Depositary  Receipts
or  convertible debentures, will be listed on securities exchanges in Japan. The
Portfolio may also invest  in equity securities of  Japanese companies that  are
traded in an over-the-counter market.
 
                                       22
<PAGE>
    The  Portfolio may  also invest  up to 20%  of its  total assets  in cash or
short-term government  or  other  short-term  prime  obligations  or  repurchase
agreements  so  that  funds  may  be  readily  available  for  general corporate
purposes,  including  the  payment  of  dividends,  redemptions  and   operating
expenses,  for investment in securities through exercise of rights or otherwise.
For temporary defensive purposes,  the Portfolio may invest  some or all of  its
assets in cash or such short-term obligations.
 
    Although  the  Portfolio will  not invest  for short-term  trading purposes,
investment securities may be sold from time to time without regard to the length
of time  they  have been  held.  It is  anticipated  that the  annual  portfolio
turnover rate of the Portfolio will not exceed 100% under normal circumstances.
 
    Any remaining assets of the Portfolio not invested as described above may be
invested  in  certain  securities or  obligations  as set  forth  in "Additional
Investment Information" below.
 
    RISK FACTORS  RELATING  TO  JAPANESE EQUITY  PORTFOLIO.    Investors  should
consider the following factors inherent in investment in Japan.
 
    TRADE  ISSUES.  Because  of the concentration of  Japanese exports in highly
visible products such as automobiles, machine tools and semiconductors, and  the
large  trade surpluses ensuing therefrom,  Japan is in a  difficult phase in its
relation with  its trading  partners,  particularly the  U.S., where  the  trade
imbalance  is the  greatest. Retaliatory action  taken by  such trading partners
could affect  the  ability  of  Japanese companies  to  export  goods  to  these
countries,  which  could  negatively  impact  the  value  of  securities  in the
Portfolio.
 
    CURRENCY FACTORS.   Over  a long  period  of years,  the yen  has  generally
appreciated  in relation to the dollar. The  yen's appreciation would add to the
returns of dollars  invested through the  Portfolio in Japan.  A decline in  the
value  of the yen would have the  opposite effect, adversely affecting the value
of the Portfolio in dollar terms.
 
    THE JAPANESE STOCK  MARKET.  Like  other stock markets,  the Japanese  stock
market  can be volatile. A  decline in the market may  have an adverse effect on
the availability of credit and on the value of the substantial stock holdings of
Japanese companies in particular, Japanese banks, insurance companies and  other
financial  institutions. A decline  in the market may  contribute to weakness in
Japan's economy. The common stocks of many Japanese companies continue to  trade
at  high price-earnings ratios even after the recent market decline. Differences
in accounting methods  make it  difficult to  compare the  earnings of  Japanese
companies  with those  of companies in  other countries, especially  the U.S. In
general, however, reported net income in  Japan is understated relative to  U.S.
accounting  standards. In addition, Japanese  companies have tended historically
to have higher  growth rates than  U.S. companies, and  Japanese interest  rates
have generally been lower than in the U.S., both of which factors tend to result
in  lower discount rates and  higher price-earnings ratios in  Japan than in the
U.S.
 
THE LATIN AMERICAN PORTFOLIO
 
    The investment  objective  of  the Latin  American  Portfolio  is  long-term
capital appreciation. The Portfolio seeks to achieve this objective by investing
primarily  in equity securities (i)  of companies organized in  or for which the
principal securities trading market is in  Latin America, (ii) denominated in  a
Latin  American  currency issued  by companies  to  finance operations  in Latin
America, or (iii) of companies that alone or on a consolidated basis derive  50%
or  more of  their annual  revenues from  either goods  produced, sales  made or
services
 
                                       23
<PAGE>
performed in  Latin  America (collectively,  "Latin  American issuers")  and  by
investing, from time to time, in debt securities issued or guaranteed by a Latin
American  government or governmental entity ("Sovereign  Debt"). Income is not a
consideration in selecting investments or an investment objective.
 
    Under normal conditions, substantially  all, but not less  than 80%, of  the
Portfolio's  total assets  are invested in  equity securities  of Latin American
issuers and in Sovereign Debt. For purposes of this Prospectus, unless otherwise
indicated,  Latin  America  consists  of  Argentina,  Bolivia,  Brazil,   Chile,
Colombia,  Costa  Rica,  Cuba,  the Dominican  Republic,  Ecuador,  El Salvador,
Guatemala, Honduras,  Mexico, Nicaragua,  Panama,  Paraguay, Peru,  Uruguay  and
Venezuela.  See "Additional  Investment Information  -- Foreign  Investment Risk
Factors" for a discussion  of the nature of  information publicly available  for
non-U.S.  companies. With  respect to  the Portfolio,  equity securities include
common and  preferred stocks,  convertible securities,  rights and  warrants  to
purchase  common  stocks,  equity  interests  in  trusts  or  partnerships,  and
American,  Global  or  other  types  of  Depositary  Receipts.  See  "Additional
Investment Information -- Depositary Receipts."
 
    The  Portfolio  focuses  its  investments  in  listed  equity  securities in
Argentina, Brazil, Chile and Mexico, the most developed capital markets in Latin
America. The Portfolio expects, under normal market conditions, to have at least
55% of its total assets invested in listed equity securities of issuers in these
four countries. In addition, the Portfolio actively invests in markets in  other
Latin  American countries such as Colombia, Peru and Venezuela. The Portfolio is
not limited in the extent to which  it may invest in any Latin American  country
and  intends to invest opportunistically as  markets develop. The portion of the
Portfolio's holdings in any Latin American country will vary from time to  time,
although  the portion of  the Portfolio's assets  invested in Chile  may tend to
vary less than the portions invested in other Latin American countries  because,
with   limited  exceptions,  capital  invested  in  Chile  currently  cannot  be
repatriated for one year. See  "Additional Investment Information --  Investment
Procedures:  Argentina, Brazil, Chile and Mexico" in the Statement of Additional
Information.
 
    The governments  of  some Latin  American  countries have  been  engaged  in
programs  of  selling  part  or  all of  their  stakes  in  government  owned or
controlled   enterprises   ("privatizations").   The   Adviser   believes   that
privatizations   may  offer  investors  opportunities  for  significant  capital
appreciation and intends to invest assets of the Portfolio in privatizations  in
appropriate  circumstances. In certain Latin  American countries, the ability of
foreign entities, such as the Portfolio, to participate in privatizations may be
limited by local law, or  the terms on which the  Portfolio may be permitted  to
participate  may be less advantageous than  those for local investors. There can
be no assurance that Latin American governments will continue to sell  companies
currently  owned or  controlled by  them or  that any  privatization programs in
which the Portfolio participates will be successful.
 
    Several Latin  American countries  have  adopted debt  conversion  programs,
pursuant  to which investors  may use Sovereign  Debt of a  country, directly or
indirectly, to make  investments in local  companies. The terms  of the  various
programs vary from country to country although each program includes significant
restrictions  on the application of the  proceeds received in the conversion and
on the remittance of profits on the investment and of the invested capital.  The
Portfolio  may  participate  in  Latin American  debt  conversion  programs. The
Adviser will evaluate opportunities to  enter into debt conversion  transactions
as they arise.
 
                                       24
<PAGE>
    Equity  securities in which the Portfolio  may invest include those that are
neither listed on a stock exchange  nor traded over-the-counter. As a result  of
the  absence of a public  trading market for these  securities, they may be less
liquid than publicly traded  securities. See "Additional Investment  Information
- -- Non-Publicly Traded Securities, Private Placements and Restricted Securities"
below.
 
    To  the  extent  that the  Portfolio's  assets  are not  invested  in equity
securities of Latin American issuers or in Sovereign Debt, the remainder of  the
assets  may be invested in  (i) debt securities of  Latin American issuers, (ii)
equity or  debt  securities of  corporate  or governmental  issuers  located  in
countries  outside  Latin America,  and  (iii) short-term  and  medium-term debt
securities of the  type described  under "Additional  Investment Information  --
Temporary  Investments" below.  The Portfolio's assets  may be  invested in debt
securities when the Portfolio believes that, based upon factors such as relative
interest rate  levels and  foreign exchange  rates, such  debt securities  offer
opportunities  for long-term capital appreciation. It is likely that many of the
debt securities  in  which  the  Portfolio will  invest  will  be  unrated.  The
Portfolio  may  invest up  to 20%  of its  total assets  in securities  that are
determined by the Adviser to be comparable to securities rated below  investment
grade  by  S&P  or Moody's  ("junk  bonds"). Such  lower-quality  securities are
regarded as being predominantly speculative  and involve significant risks.  See
"Additional Investment Information -- Lower Rated Debt Securities."
 
    The  Portfolio's  holdings  of lower-quality  debt  securities  will consist
predominantly of Sovereign Debt, much  of which trades at substantial  discounts
from  face value and  which may include Sovereign  Debt comparable to securities
rated as low as D by S&P or C by Moody's. The Portfolio may invest in  Sovereign
Debt  to  hold and  trade in  appropriate circumstances,  as well  as to  use to
participate in debt for equity conversion programs. The Portfolio will invest in
Sovereign  Debt  only  when  the  Portfolio  believes  such  investments   offer
opportunities  for long- term capital appreciation. Investment in Sovereign Debt
involves a high degree of risk  and such securities are generally considered  to
be  speculative in nature.  See "Additional Investment  Information -- Sovereign
Debt."
 
    For temporary defensive purposes, the Portfolio may invest less than 80%  of
its  total assets  in Latin  American equity  securities and  Sovereign Debt, in
which case the Portfolio may  invest in other equity  or debt securities or  may
invest  in  certain  short-term  (less  than  twelve  months  to  maturity)  and
medium-term (not greater than  five years to maturity)  debt securities or  hold
cash. See "Additional Investment Information -- Temporary Investments."
 
    The Portfolio may enter into forward foreign currency exchange contracts and
foreign  currency  futures contracts,  purchase and  write  (sell) put  and call
options  on  securities,  foreign  currency  and  on  foreign  currency  futures
contracts,  and enter into  stock index and interest  rate futures contracts and
options thereon. See  "Additional Investment Information."  There currently  are
limited  options and futures  markets for Latin  American currencies, securities
and indexes, and the  nature of the  strategies adopted by  the Adviser and  the
extent  to which those strategies  are used depends on  the development of those
markets. The Portfolio may also  from time to time  lend securities (but not  in
excess  of 20% of its  total assets) from its  portfolio to brokers, dealers and
financial institutions.  See  "Additional  Investment Information  --  Loans  of
Portfolio Securities."
 
    The  Portfolio will  not invest  more than  25% of  its total  assets in one
industry except and  to the extent,  and only for  such period of  time as,  the
Board of Directors determines in view of the considerations discussed below that
it is appropriate and in the best interest of the Portfolio and its shareholders
to invest more than 25% of the Portfolio's total assets in companies involved in
the    telecommunications    industry    or    financial    services   industry,
 
                                       25
<PAGE>
respectively. Since  the  securities markets  of  Latin American  countries  are
emerging  markets characterized  by a relatively  small number of  issues, it is
possible that one  or more markets  may on  occasion be dominated  by issues  of
companies  engaged in  these two  industries. In  addition, it  is possible that
government privatizations in certain  Latin American countries, which  currently
represent  a primary  source of  new issues in  many Latin  American markets and
often represent attractive  investment opportunities,  will occur  in these  two
industries.  As a result, the Portfolio has  adopted a policy under which it may
invest more  than 25%  of its  total assets  in securities  of issuers  in  such
industries.  The Portfolio would only take this action if the Board of Directors
determines that  the  Latin American  markets  are dominated  by  securities  of
issuers  in  such  industries and  that,  in  light of  the  anticipated return,
investment quality, availability and liquidity of the issues in such industries,
the Portfolio's ability to achieve its  investment objective would, in light  of
its investment policies and limitations, be materially adversely affected if the
Portfolios  were not able to invest greater than 25% of its total assets in such
industries. In the event that the Board of Directors permits greater than 25% of
the Portfolio's  total  assets  to  be invested  in  the  telecommunications  or
financial   services  industry,  the  Portfolio  may  be  exposed  to  increased
investment risks  peculiar  to that  industry.  The Portfolio  will  notify  its
shareholders  of any  decision by  the Board of  Directors to  permit (or cease)
investments  of  more  than  25%  of   the  Portfolio's  total  assets  in   the
telecommunications  or  financial services  industry. Such  notice will,  to the
extent applicable,  include  a  discussion of  any  increased  investment  risks
peculiar to such industry to which the Portfolio may be exposed.
 
    The  Portfolio intends to purchase and hold securities for long-term capital
appreciation and does not expect to  trade for short-term gain. Accordingly,  it
is  anticipated that the annual portfolio turnover rate normally will not exceed
50%, although  in  any  particular  year,  market  conditions  could  result  in
portfolio  activity at a  greater or lesser  rate than anticipated.  The rate of
portfolio turnover will  not be a  limiting factor when  the Portfolio deems  it
appropriate  to  purchase  or sell  securities.  However, the  U.S.  federal tax
requirement that the Portfolio derive less than 30% of its gross income from the
sale or disposition  of securities  held less than  three months  may limit  the
Portfolio's ability to dispose of its securities.
 
    Any remaining assets of the Portfolio not invested as described above may be
invested  in  certain  securities or  obligations  as set  forth  in "Additional
Investment Information" below.
 
                       ADDITIONAL INVESTMENT INFORMATION
 
    BORROWING AND OTHER  FORMS OF  LEVERAGE.   The Latin  American Portfolio  is
authorized  to borrow money from banks and  other entities in an amount equal to
up to 33  1/3% of  its total  assets (including  the amount  borrowed) less  all
liabilities  and indebtedness other than the borrowing, and may use the proceeds
of the borrowing for investment purposes or to pay dividends. Borrowing  creates
leverage  which  is  a  speculative characteristic.  Although  the  Portfolio is
authorized to  borrow,  it  will do  so  only  when the  Adviser  believes  that
borrowing  will benefit the  Portfolio after taking  into account considerations
such as the costs of borrowing  and the likely investment returns on  securities
purchased  with  borrowed monies.  Borrowing by  the  Portfolio will  create the
opportunity for increased net income but, at the same time, will involve special
risk considerations. Leveraging resulting  from borrowing will magnify  declines
as well as increases in the Portfolio's net asset value per share and net yield.
 
    The  Portfolio expects that all  of its borrowing will  be made on a secured
basis. The Portfolio's Custodian will  either segregate the assets securing  the
borrowing  for  the  benefit  of  the  lenders  or  arrangements  will  be  made
 
                                       26
<PAGE>
with a suitable sub-custodian. If assets  used to secure the borrowing  decrease
in  value, the Portfolio may be required  to pledge additional collateral to the
lender in the form of cash or securities to avoid liquidation of those assets.
 
    DEPOSITARY RECEIPTS.  The  Asian Equity, Global  Equity, Latin American  and
Japanese  Equity Portfolios may invest  in American Depositary Receipts ("ADRs")
and the Global  Equity and Latin  American Portfolios may  also invest in  other
Depositary  Receipts,  including Global  Depositary Receipts  ("GDRs"), European
Depositary Receipts ("EDRs") and other Depositary Receipts (which, together with
ADRs, GDRs and  EDRs, are  hereinafter collectively referred  to as  "Depositary
Receipts"),  to the extent that such  Depositary Receipts become available. ADRs
are  securities,  typically   issued  by   a  U.S.   financial  institution   (a
"depositary"),  that evidence  ownership interests  in a  security or  a pool of
securities issued by a  foreign issuer (the  "underlying issuer") and  deposited
with the depositary. ADRs include American Depositary Shares and New York Shares
and  may be "sponsored" or "unsponsored." Sponsored ADRs are established jointly
by a  depositary and  the underlying  issuer, whereas  unsponsored ADRs  may  be
established  by  a depositary  without participation  by the  underlying issuer.
GDRs, EDRs  and other  types  of Depositary  Receipts  are typically  issued  by
foreign depositaries, although they may also be issued by U.S. depositaries, and
evidence  ownership  interests in  a security  or pool  of securities  issued by
either a  foreign  or a  U.S.  corporation. Generally,  Depositary  Receipts  in
registered  form  are  designed  for  use  in  the  U.S.  securities  market and
Depositary Receipts in bearer  form are designed for  use in securities  markets
outside the United States. The Portfolio may invest in sponsored and unsponsored
Depositary  Receipts. For purposes  of the Portfolio's  investment policies, the
Portfolio's investments in Depositary Receipts will be deemed to be  investments
in the underlying securities.
 
    FOREIGN  INVESTMENT.   Investment in  securities of  foreign issuers  and in
foreign branches of domestic banks involves somewhat different investment  risks
than  those affecting securities of U.S.  domestic issuers. There may be limited
publicly available  information with  respect to  foreign issuers,  and  foreign
issuers  are not generally subject to uniform accounting, auditing and financial
and other reporting standards and requirements comparable to those applicable to
U.S. companies. There may also be less government supervision and regulation  of
foreign securities exchanges, brokers and listed companies than in the U.S. Many
foreign  securities markets  have substantially  less volume  than U.S. national
securities exchanges, and securities of some foreign issuers are less liquid and
more  volatile  than  securities  of  comparable  domestic  issuers.   Brokerage
commissions  and  other transaction  costs on  foreign securities  exchanges are
generally higher than in the U.S. Dividends and interest paid by foreign issuers
may be subject to  withholding and other foreign  taxes, which may decrease  the
net  return on foreign investments as compared to dividends and interest paid to
the Portfolios by U.S. companies, and it is not expected that a Portfolio or its
shareholders would be able to claim a credit for U.S. tax purposes with  respect
to  any  such  foreign  taxes.  See  "Taxes."  Additional  risks  include future
political and economic developments, the possibility that a foreign jurisdiction
might impose  or change  withholding taxes  on income  payable with  respect  to
foreign  securities, possible  seizure, nationalization or  expropriation of the
foreign issuer  or  foreign  deposits  and  the  possible  adoption  of  foreign
governmental  restrictions such  as exchange controls.  Many of  the emerging or
developing countries  may  have less  stable  political environments  than  more
developed  countries. Also, it may  be more difficult to  obtain a judgment in a
court outside the United States.
 
    Investments in securities of foreign  issuers are frequently denominated  in
foreign  currencies, and the Portfolios may temporarily hold uninvested reserves
in   bank    deposits   in    foreign   currencies.    Therefore,   the    value
 
                                       27
<PAGE>
of each Portfolio's assets as measured in U.S. dollars may be affected favorably
or unfavorably by changes in currency rates and in exchange control regulations,
and  the  Portfolios  may incur  costs  in connection  with  conversions between
various currencies.
 
    FORWARD FOREIGN CURRENCY EXCHANGE CONTRACTS.  Each Portfolio may enter  into
forward  foreign currency exchange contracts  ("forward contracts") that provide
for the purchase of  or sale of an  amount of a specified  currency at a  future
date. Purposes for which such contracts may be used include protecting against a
decline in a foreign currency against the U.S. dollar between the trade date and
settlement  date when a Portfolio purchases  or sells securities, locking in the
U.S. dollar value of  dividends declared on securities  held by a Portfolio  and
generally  protecting the  U.S. dollar value  of securities held  by a Portfolio
against exchange  rate  fluctuations. Such  contracts  may  also be  used  as  a
protective measure against the effects of fluctuating rates of currency exchange
and  exchange control regulations. While such forward contracts may limit losses
to a Portfolio as a  result of exchange rate  fluctuation, they will also  limit
any  gains that may  otherwise have been realized.  The Latin American Portfolio
may  also  enter  into  foreign  currency  futures  contracts.  See  "Investment
Objectives and Policies -- Forward Currency Exchange Contracts" in the Statement
of Additional Information. Except in circumstances where segregated accounts are
not  required by the 1940 Act and  the rules adopted thereunder, the Portfolio's
Custodian will  place  cash,  U.S. government  securities,  or  high-grade  debt
securities  into a segregated account  of a Portfolio in  an amount equal to the
value of such Portfolio's total assets committed to the consummation of  forward
foreign  currency exchange contracts.  If the value of  the securities placed in
the segregated account declines, additional cash or securities will be placed in
the account on a daily basis so that  the value of the account will be at  least
equal  to  the  amount of  such  Portfolio's  commitments with  respect  to such
contracts. See "Investment Objectives and  Policies -- Forward Foreign  Currency
Exchange Contracts" in the Statement of Additional Information.
 
    FUTURES  CONTRACTS AND  OPTIONS ON  FUTURES CONTRACTS.   In  order to remain
fully invested, and to  reduce transaction costs,  the Latin American  Portfolio
may   utilize  appropriate  securities  index   futures  contracts,  options  on
securities index futures contracts, appropriate interest rate futures  contracts
and  options on  interest rate  futures contracts  to a  limited extent. Because
transactions costs associated  with futures and  options may be  lower than  the
costs  of investing in securities directly, it is expected that the use of index
futures and options to  facilitate cash flows may  reduce a Portfolio's  overall
transactions  costs. The Portfolio may  sell indexed financial futures contracts
in anticipation of or during a market decline to attempt to offset the  decrease
in market value of securities in its portfolio that might otherwise result. When
the  Portfolio is not  fully invested and the  Adviser anticipates a significant
market advance,  it may  purchase stock  index futures  in order  to gain  rapid
market  exposure that may  in part or  entirely offset increases  in the cost of
securities that  it intends  to purchase.  In a  substantial majority  of  these
transactions,  the Portfolio will  purchase such securities  upon termination of
the futures position but under unusual market conditions, a futures position may
be terminated without  the corresponding purchase  of securities. The  Portfolio
will engage in futures and options transactions only for hedging purposes.
 
    The  Portfolio will engage only in  transactions in securities index futures
contracts, interest rate futures contracts and options thereon which are  traded
on  a recognized  securities or  futures exchange.  There currently  are limited
securities index  futures, interest  rate futures  and options  on such  futures
markets  in  many  countries,  particularly  emerging  countries  such  as Latin
American countries, and the nature of the strategies adopted by the Adviser  and
the  extent to which those strategies are used will depend on the development of
such markets.
 
                                       28
<PAGE>
    The Portfolio may enter into futures contracts and options thereon  provided
that not more than 5% of the Portfolio's total assets are required as deposit to
secure obligations under such contracts, and provided further that not more than
20%  of the Portfolio's total  assets, in the aggregate  are invested in futures
contracts and options transactions.
 
    The primary risks  associated with the  use of futures  and options are  (i)
imperfect  correlation between the change in market  value of the stocks held by
the Portfolio  and the  prices of  futures and  options relating  to the  stocks
purchased or sold by the Portfolio, and (ii) possible lack of a liquid secondary
market  for a futures  contract and the  resulting inability to  close a futures
position which could have an adverse impact on the Portfolio's ability to hedge.
The risk of  loss in  trading on  futures contracts  in some  strategies can  be
substantial, due both to the low margin deposits required and the extremely high
degree  of leverage involved in futures pricing. Gains and losses on futures and
options depend on the  Adviser's ability to predict  correctly the direction  of
stock  prices, interest rates, and other economic factors. In the opinion of the
Directors, the risk that  the Portfolio will  be unable to  close out a  futures
position  or options  contract will be  minimized by only  entering into futures
contracts or  options  transactions for  which  there  appears to  be  a  liquid
secondary  market. For more detailed  information about futures transactions see
"Investment Objectives and Policies" in the Statement of Additional Information.
 
    INVESTMENT FUNDS.  Some  emerging countries have  laws and regulations  that
currently  preclude  direct  foreign  investment  in  the  securities  of  their
companies. However, indirect foreign investment  in the securities of  companies
listed  and traded  on the  stock exchanges in  these countries  is permitted by
certain emerging countries through investment funds which have been specifically
authorized. The Latin American  Portfolio may invest  in these investment  funds
subject to the provisions of the Investment Company Act of 1940, as amended (the
"1940  Act"), and  other applicable  laws as  discussed below  under "Investment
Restrictions."  If  the  Portfolio  invests   in  such  investment  funds,   the
Portfolio's  shareholders will  bear not only  their proportionate  share of the
expenses of the  Portfolio (including  operating expenses  and the  fees of  the
Adviser),  but  also will  indirectly bear  similar  expenses of  the underlying
investment funds.
 
    Certain of the investment funds referred  to in the preceding paragraph  are
advised  by the Adviser.  The Portfolio may,  to the extent  permitted under the
1940 Act and  other applicable  law, invest in  these investment  funds. If  the
Portfolio  does elect to make an investment  in such an investment fund, it will
only purchase the securities of such investment fund in the secondary market.
 
    LOANS OF PORTFOLIO SECURITIES.   Each Portfolio may  lend its securities  to
brokers, dealers, domestic and foreign banks or other financial institutions for
the purpose of increasing its net investment income. These loans must be secured
continuously  by cash or equivalent collateral or by a letter of credit at least
equal to the  market value  of the securities  loaned plus  accrued interest  or
income.  There may be risks of delay in  recovery of the securities or even loss
of rights  in  the  collateral  should  the  borrower  of  the  securities  fail
financially.  A  Portfolio  will  not enter  into  securities  loan transactions
exceeding in the aggregate 33 1/3% of the market value of the Portfolio's  total
assets  (exceeding in the aggregate 20% of  such value with respect to the Latin
American Portfolio). For more detailed information about securities lending, see
"Investment Objectives and Policies" in the Statement of Additional Information.
 
    LOWER RATED DEBT  SECURITIES.  The  Latin American Portfolio  may invest  in
lower rated or unrated debt securities, commonly referred to as "junk bonds." In
addition,    the    emerging   country    debt    securities   in    which   the
 
                                       29
<PAGE>
Portfolio may invest  are subject to  risk and will  not be required  to meet  a
minimum  rating  standard and  may  not be  rated.  Fixed income  securities are
subject to the  risk of  an issuer's inability  to meet  principal and  interest
payments  on the  obligations (credit  risk) and  may also  be subject  to price
volatility due to such factors  as interest rate sensitivity, market  perception
of  the  creditworthiness of  the issuer  and  general market  liquidity (market
risk).  Lower  rated  or  unrated  securities  are  more  likely  to  react   to
developments  affecting  market  and  credit risk  than  are  more  highly rated
securities, which react primarily to movements in the general level of  interest
rates.  The market values of fixed-income securities tend to vary inversely with
the level of interest rates. Yields and market values of lower rated and unrated
debt securities will fluctuate over time, reflecting not only changing  interest
rates but the market's perception of credit quality and the outlook for economic
growth.  When economic  conditions appear to  be deteriorating,  medium to lower
rated securities may  decline in  value due  to heightened  concern over  credit
quality,  regardless of prevailing interest rates.  Fluctuations in the value of
the Portfolio's investments will be reflected in the Portfolio's net asset value
per share. The  Adviser considers  both credit risk  and market  risk in  making
investment  decisions for the Portfolio. Investors should carefully consider the
relative risks  of investing  in lower  rated and  unrated debt  securities  and
understand   that  such  securities  are  not  generally  meant  for  short-term
investing.
 
    The U.S.  corporate  lower  rated  and unrated  debt  securities  market  is
relatively  new  and its  recent  growth paralleled  a  long period  of economic
expansion and an increase in merger, acquisition and leveraged buyout  activity.
Adverse  economic developments may  disrupt the market  for U.S. corporate lower
rated and unrated debt securities and for emerging country debt securities. Such
disruptions may  severely  affect  the ability  of  issuers,  especially  highly
leveraged  issuers,  to  service  their  debt  obligations  or  to  repay  their
obligations upon maturity. In addition, the secondary market for lower rated and
unrated debt securities, which is concentrated in relatively few market  makers,
may  not be as liquid as the  secondary market for more highly rated securities.
As a result, the Adviser could find  it more difficult to sell these  securities
or  may  be able  to  sell the  securities  only at  prices  lower than  if such
securities were widely traded. In addition there may be limited trading  markets
for  debt securities of  issuers located in  emerging countries. Prices realized
upon  the  sale  of  such  lower  rated  or  unrated  securities,  under   these
circumstances,  may be less than the  prices used in calculating the Portfolio's
net asset value.
 
    Prices for  lower rated  and  unrated debt  securities  may be  affected  by
legislative  and regulatory developments. These  laws could adversely affect the
Portfolio's net asset value and  investment practices, the secondary market  for
lower  rated and unrated debt securities,  the financial condition of issuers of
such securities  and the  value  of outstanding  lower  rated and  unrated  debt
securities.  For example, U.S. federal  legislation requiring the divestiture by
federally insured savings and  loan associations of  their investments in  lower
rated  and unrated debt securities and limiting the deductibility of interest by
certain corporate issuers of lower  rated and unrated debt securities  adversely
affected the market in recent years.
 
    Lower  rated or unrated debt obligations also present risks based on payment
expectations. If an issuer calls  the obligations for redemption, the  Portfolio
may  have to replace the security with a lower yielding security, resulting in a
decreased return  for investors.  If the  Portfolio experiences  unexpected  net
redemptions,  it may be forced to sell its higher rated securities, resulting in
a decline in the overall credit quality of the Portfolio's investment  portfolio
and  increasing the exposure  of the Portfolio  to the risks  of lower rated and
unrated debt securities.
 
                                       30
<PAGE>
    MONEY MARKET INSTRUMENTS.  The Portfolios  are permitted to invest in  money
market  instruments,  although  each  Portfolio  intends  to  stay  invested  in
securities  satisfying  their  primary   investment  objective  to  the   extent
practical.  Each  Portfolio  may  make money  market  investments  pending other
investment or settlement  for liquidity,  or in adverse  market conditions.  The
money market investments permitted for the Portfolios include obligations of the
U.S.  Government and its agencies  and instrumentalities, obligations of foreign
sovereignties,  other   debt  securities,   commercial  paper   including   bank
obligations,  certificates  of  deposit  (including  Eurodollar  certificates of
deposit) and repurchase  agreements. For more  detailed information about  these
money  market investments,  see "Description of  Securities and  Ratings" in the
Statement of Additional Information.
 
    NON-PUBLICLY  TRADED   SECURITIES,   PRIVATE   PLACEMENTS   AND   RESTRICTED
SECURITIES.    The  International Small  Cap  Portfolio and  the  Latin American
Portfolio may invest in securities that  are neither listed on a stock  exchange
nor   traded  over-the-counter,  including  privately  placed  securities.  Such
unlisted equity securities may involve a higher degree of business and financial
risk that can  result in substantial  losses. As a  result of the  absence of  a
public  trading  market  for these  securities,  they  may be  less  liquid than
publicly traded securities. Although these securities may be resold in privately
negotiated transactions, the prices realized from these sales could be less than
those originally paid by the Portfolio or  less than what may be considered  the
fair  value of such securities. Further, more companies whose securities are not
publicly traded  may  not  be  subject to  the  disclosure  and  other  investor
protection  requirements  which might  be  applicable if  their  securities were
publicly traded. If  such securities  are required  to be  registered under  the
securities  laws of one or more jurisdictions before being resold, the Portfolio
may be required to bear the expenses of registration. As a general matter,  each
Portfolio may not invest more than 15% of its net assets in illiquid securities,
including  securities for which there is  no readily available secondary market,
nor more than 10%  of its total  assets in securities  that are restricted  from
sale  to  the public  without registration  ("Restricted Securities")  under the
Securities Act of 1933, as amended (the "1933 Act"). Nevertheless, to the extent
it can do so consistent with the foregoing limits, each Portfolio may invest  up
to 25% of its total assets in Restricted Securities that can be offered and sold
to  qualified  institutional  buyers  under  Rule  144A  under  that  Act ("144A
Securities"). The Board of Directors has adopted guidelines and delegated to the
Adviser, subject  to  the supervision  of  the  Board of  Directors,  the  daily
function  of determining and  monitoring the liquidity  of 144A securities. Rule
144A securities may become  illiquid if qualified  institutional buyers are  not
interested  in acquiring the securities.  Investors should note that investments
of 5% of a Portfolio's total assets may be considered a speculative activity and
may involve greater risk and expense to the Portfolio.
 
    OPTIONS TRANSACTIONS.  The Latin American Portfolio may seek to increase its
return or  may hedge  all or  a  portion of  its portfolio  investments  through
options  with  respect to  securities  in which  the  Portfolio may  invest. The
Portfolio will engage  in transactions  in such options  which are  traded on  a
recognized  securities or futures exchange and in over-the-counter options where
the option counterparty has a minimum net worth of $20 million. There  currently
are  limited  options markets  in emerging  countries, including  Latin American
countries and the nature of the strategies adopted by the Adviser and the extent
to which those strategies are used will depend on the development of such option
markets.
 
    The Latin American  Portfolio may  write (i.e., sell)  covered call  options
which give the purchaser the right to buy the underlying security covered by the
option  from the Portfolio at the stated exercise price. A "covered" call option
means that so long as the Portfolio is obligated as the writer of the option, it
will own (i) the
 
                                       31
<PAGE>
underlying securities subject to the  option, or (ii) securities convertible  or
exchangeable  without  the  payment  of any  consideration  into  the securities
subject to  the option.  As  a matter  of operating  policy,  the value  of  the
underlying  securities on which options will be written at any one time will not
exceed 5% of  the total assets  of the Portfolio.  In addition, as  a matter  of
operating  policy, the Portfolio  will neither purchase or  write put options on
securities nor purchase call  options on securities  (except in connection  with
closing purchase transactions).
 
    The  Latin  American  Portfolio will  receive  a premium  from  writing call
options, which increases the  Portfolio's return on  the underlying security  in
the  event  the option  expires unexercised  or is  closed out  at a  profit. By
writing a  call, the  Portfolio will  limit its  opportunity to  profit from  an
increase in the market value of the underlying security above the exercise price
of  the option for as long as the Portfolio's obligation as writer of the option
continues. Thus, in some  periods the Portfolio will  receive less total  return
and in other periods greater total return from writing covered call options than
it  would have received from  its underlying securities had  it not written call
options.
 
    The Latin  American  Portfolio  may  also write  (i.e.,  sell)  covered  put
options.  By selling a covered put option, the Portfolio incurs an obligation to
buy the security  underlying the option  from the  purchaser of the  put at  the
option's exercise price at any time during the option period, at the purchaser's
election  (certain options written  by the Portfolio will  be exercisable by the
purchaser only on a specific date). Generally, a put option is "covered" if  the
Portfolio  maintains cash, U.S.  Government securities or  other high grade debt
obligations equal to the exercise price of the option or if the Portfolio  holds
a  put option on the same underlying  security with a similar or higher exercise
price. The  Portfolio may  sell put  options  to receive  the premiums  paid  by
purchasers  and to close out  a long put option  position. In addition, when the
Adviser wishes to purchase a security at  a price lower than its current  market
price, the Portfolio may write a covered put at an exercise price reflecting the
lower purchase price sought.
 
    The Portfolio may also purchase put or call options on individual securities
or baskets of securities. When the Portfolio purchases a call option it acquires
the  right to  buy a  designated security at  a designated  price (the "exercise
price"), and when the Portfolio purchases a put option it acquires the right  to
sell  a designated security at  the exercise price, in each  case on or before a
specified date (the "termination date"), usually not more than nine months  from
the  date the option is issued. The Portfolio may purchase call options to close
out a covered call position or to protect against an increase in the price of  a
security  it anticipates purchasing.  The Portfolio may  purchase put options on
securities which it holds in its  portfolio only to protect against an  increase
in the price of a security it anticipates purchasing. The Portfolio may purchase
put options on securities which it holds in its portfolio only to protect itself
against  a decline in the value of the  security. If the value of the underlying
security were to fall below the exercise price of the put purchased in an amount
greater than  the premium  paid for  the option,  the Portfolio  would incur  no
additional  loss.  The Portfolio  may  also purchase  put  options to  close out
written put  positions in  a  manner similar  to  call option  closing  purchase
transactions.  There are no other limits  on the Portfolio's ability to purchase
call and put options.
 
    The primary  risks associated  with the  use of  options are  (i)  imperfect
correlation  between the change  in market value  of the securities  held by the
Portfolio and the prices of options relating to the securities purchased or sold
by the Portfolio; and  (ii) possible lack  of a liquid  secondary market for  an
option.  Options that  are not  traded on  an exchange  (OTC options)  are often
considered illiquid  and  may be  difficult  to value.  In  the opinion  of  the
Adviser,  the risk that  that Portfolio will  be unable to  close out an options
contract will be minimized by only entering into options transactions for  which
there appears to be a liquid secondary market.
 
                                       32
<PAGE>
    REPURCHASE  AGREEMENTS.  Each Portfolio may enter into repurchase agreements
with brokers, dealers or  banks that meet the  credit guidelines established  by
the  Fund's Board of Directors. In a  repurchase agreement, the Portfolio buys a
security from a seller  that has agreed  to repurchase it  at a mutually  agreed
upon  date and price, reflecting the interest rate effective for the term of the
agreement. The term of  these agreements is usually  from overnight to one  week
and  never exceeds  one year.  Repurchase agreements  may be  viewed as  a fully
collateralized loan  of money  by the  Portfolio to  the seller.  The  Portfolio
always  receives securities with a  market value at least  equal to the purchase
price (including accrued interest) as  collateral, and this value is  maintained
during  the term  of the  agreement. If the  seller defaults  and the collateral
value declines, the Portfolio might incur a loss. If bankruptcy proceedings  are
commenced  with  respect to  the seller,  the  Portfolio's realization  upon the
collateral may  be  delayed or  limited.  The aggregate  of  certain  repurchase
agreements  and  certain  other  investments  is  limited  as  set  forth  under
"Investment Limitations."
 
SHORT SALES
 
    The Latin American  Portfolio may from  time to time  sell securities  short
without  limitation, although  initially the Portfolio  does not  intend to sell
securities short. A  short sale is  a transaction in  which the Portfolio  would
sell  securities it does not own (but has borrowed) in anticipation of a decline
in the market price of  securities. When the Portfolio  makes a short sale,  the
proceeds  it receives from the sale will be held on behalf of a broker until the
Portfolio replaces the  borrowed securities.  To deliver the  securities to  the
buyer,  the  Portfolio will  need  to arrange  through  a broker  to  borrow the
securities and, in so doing, the Portfolio will become obligated to replace  the
securities  borrowed at their market price  at the time of replacement, whatever
that price  may be.  The Portfolio  may  have to  pay a  premium to  borrow  the
securities  and must  pay any  dividends or  interest payable  on the securities
until they are replaced.
 
    The Portfolio's obligation to replace the securities borrowed in  connection
with  a short sale will be secured  by collateral deposited with the broker that
consists of cash, U.S.  Government Securities or other  liquid, high grade  debt
obligations.  In addition, the Portfolio will place in a segregated account with
its Custodian an amount of cash, U.S. Government Securities or other liquid high
grade debt obligations equal to the  difference, if any, between (1) the  market
value  of the securities sold at the time they were sold short and (2) any cash,
U.S. Government Securities or other liquid high grade debt obligations deposited
as collateral with the broker in  connection with the short sale (not  including
the  proceeds of the short  sale). Short sales by  the Portfolio involve certain
risks and special considerations. Possible  losses from short sales differ  from
losses that could be incurred from a purchase of a security, because losses from
short  sales may be unlimited, whereas losses  from purchases can equal only the
total amount invested.
 
    SOVEREIGN DEBT.   The Latin American  Portfolio's holdings of  lower-quality
debt  securities will  consist predominantly  of Sovereign  Debt, much  of which
trades at substantial  discounts from face  value. The Portfolio  may invest  in
Sovereign  Debt of  emerging market countries  to hold and  trade in appropriate
circumstances  and  to  participate  in  debt  to  equity  conversion  programs.
Investment  in Sovereign Debt involves a high degree of risk and such securities
are generally  considered  speculative in  nature.  The issuer  or  governmental
authorities  that control  the repayment  of Sovereign Debt  may not  be able or
willing to repay the principal and/or  interest when due in accordance with  the
terms  of  such  debt. A  sovereign  debtor's  willingness or  ability  to repay
principal and interest due in  a timely manner may  be affected by, among  other
factors,  its  cash flow  situation,  the extent  of  its foreign  reserves, the
availability of sufficient foreign  exchange on the date  a payment is due,  the
relative  size  of  the debt  service  burden to  the  economy as  a  whole, the
sovereign debtor's policy towards the
 
                                       33
<PAGE>
International Monetary Fund (the "IMF") and the political constraints to which a
sovereign debtor may  be subject.  Sovereign debtors  may also  be dependent  on
expected  disbursements  from  foreign  governments,  multilateral  agencies and
others abroad to  reduce principal and  interest arrearages on  their debt.  The
commitment  on the part of  these governments, agencies and  others to make such
disbursements may  be  conditioned on  a  sovereign debtor's  implementation  of
economic  reforms and/or  economic performance  and the  timely service  of such
debtor's obligations. Failure to implement such reforms, achieve such levels  of
economic  performance or repay principal or interest  when due may result in the
cancellation of such third parties' commitments  to lend funds to the  sovereign
debtor,  which may further impair such debtor's ability or willingness to timely
service its debts. In certain instances,  the Portfolio may invest in  Sovereign
Debt  that is  in default as  to payments  of principal and/or  interest. To the
extent the Portfolio is holding any non-performing Sovereign Debt, it may  incur
additional  expenses  in  connection  with  any  restructuring  of  the issuer's
obligations or in otherwise enforcing its rights thereunder.
 
    TEMPORARY INVESTMENTS.  During periods in which the Adviser believes changes
in economic, financial or political conditions make it advisable, for  temporary
defensive  purposes  the Latin  American Portfolio  may  reduce its  holdings in
equity and other  securities and  may invest  in certain  short-term (less  than
twelve  months  to maturity)  and medium-term  (not greater  than five  years to
maturity) debt securities or may hold cash. The short-term and medium-term  debt
securities  in which the Portfolio may invest  consist of (a) obligations of the
United States  or emerging  country  governments (Latin  American  governments),
their  respective  agencies or  instrumentalities;  (b) bank  deposits  and bank
obligations (including  certificates  of  deposit, time  deposits  and  bankers'
acceptances)  of United States or emerging  country banks (Latin American banks)
denominated in any currency; (c) floating rate securities and other  instruments
denominated  in any currency  issued by international  development agencies; (d)
finance company and  corporate commercial paper  and other short-term  corporate
debt  obligations  of United  States  and emerging  country  corporations (Latin
American corporations) meeting the Portfolio's credit quality standards; and (e)
repurchase agreements  with  banks  and  broker-dealers  with  respect  to  such
securities.  See "Additional  Investment Information  -- Repurchase Agreements."
For temporary  defensive  purposes, the  Portfolio  intends to  invest  only  in
short-term  and medium-term debt  securities that the Adviser  believes to be of
high quality,  i.e., subject  to relatively  low  risk of  loss of  interest  or
principal  (there  is currently  no rating  system for  debt securities  in most
emerging countries, including most Latin American countries.)
 
    WHEN-ISSUED AND DELAYED DELIVERY SECURITIES.  Each Portfolio of the Fund may
purchase securities  on  a  when-issued  or  delayed  delivery  basis.  In  such
transactions,  instruments are bought with payment  and delivery taking place in
the future in order to secure what is considered to be an advantageous yield  or
price  at  the  time of  the  transaction.  Delivery of  and  payment  for these
securities may take as long  as a month or more  after the date of the  purchase
commitment  but will take place no more than 120 days after the trade date. Each
Portfolio will maintain with the Custodian a separate account with a  segregated
portfolio  of  high-grade debt  securities or  equity securities  or cash  in an
amount at  least equal  to these  commitments. The  payment obligation  and  the
interest  rates that  will be received  are each  fixed at the  time a Portfolio
enters into  the commitment  and  no interest  accrues  to the  Portfolio  until
settlement. Thus, it is possible that the market value at the time of settlement
could  be higher or lower  than the purchase price  if, among other factors, the
general level of  interest rates has  changed. It  is a current  policy of  each
Portfolio  not  to  enter  into  when-issued  commitments  or  delayed  delivery
securities exceeding in the aggregate 15% of the market value of the Portfolio's
total assets  less liabilities,  other  than the  obligations created  by  these
commitments.
 
                                       34
<PAGE>
                             INVESTMENT LIMITATIONS
 
    Each  Portfolio,  except  the  Latin American  Portfolio,  is  a diversified
investment company under the 1940 Act and is therefore subject to the  following
limitations:  (a) as to 75% of its total assets, a Portfolio may not invest more
than 5%  of  its total  assets  in the  securities  of any  one  issuer,  except
obligations  of the U.S. Government and  its agencies and instrumentalities, and
(b) a Portfolio may not own more  than 10% of the outstanding voting  securities
of  any one issuer. The Latin American Portfolio is a non-diversified investment
company under the 1940 Act, which means that the Latin American Portfolio is not
limited by  the 1940  Act in  the proportion  of its  total assets  that may  be
invested  in  the  obligations of  a  single  issuer. Thus,  the  Latin American
Portfolio may invest a greater proportion of its total assets in the  securities
of a smaller number of issuers and, as a result, will be subject to greater risk
with  respect  to  their  respective portfolio  securities.  The  Latin American
Portfolio, however,  intends to  comply  with the  diversification  requirements
imposed by the Internal Revenue Code of 1986, as amended, for qualification as a
regulated investment company. See "Taxes."
 
   
    Each  Portfolio also operates under certain investment restrictions that are
deemed fundamental limitations and may be changed only with the approval of  the
holders  of a majority  of such Portfolio's  outstanding shares. See "Investment
Limitations" in  the  Statement of  Additional  Information. In  addition,  each
Portfolio  operates  under  certain  non-fundamental  investment  limitations as
described below and in the  Statement of Additional Information. Each  Portfolio
may  not  (i) enter  into repurchase  agreements  with more  than seven  days to
maturity if, as a result, more than  15% of the market value of the  Portfolio's
net assets would be invested in these agreements and other investments for which
market  quotations are  not readily available  or which  are otherwise illiquid;
(ii) borrow money, except  from banks for  extraordinary or emergency  purposes,
and then only in amounts up to 10% of the value of the Portfolio's total assets,
taken  at cost at the time of borrowing, or purchase securities while borrowings
exceed 5%  of its  total assets,  except  the Latin  American Portfolio  is  not
subject to such limits on borrowing and may borrow from banks and other entities
in  amounts not in excess  of 33 1/3% of its  total assets (including the amount
borrowed) less liabilities;  (iii) mortgage,  pledge or  hypothecate any  assets
except  in connection with any such borrowing in  amounts up to 10% of the value
of the Portfolio's net  assets at the  time of borrowing;  (iv) invest in  fixed
time  deposits with  a duration of  over seven  calendar days; or  (v) invest in
fixed time deposits with a duration of from two business days to seven  calendar
days if more than 10% of the Portfolio's total assets would be invested in these
deposits.
    
 
                             MANAGEMENT OF THE FUND
 
    INVESTMENT  ADVISER.  Morgan Stanley Asset Management Inc. is the Investment
Adviser and Administrator of  the Fund and each  of its portfolios. The  Adviser
provides  investment advice  and portfolio  management services,  pursuant to an
Investment Advisory  Agreement and,  subject to  the supervision  of the  Fund's
Board  of  Directors,  makes  each  of  the  Portfolio's  day-to-day  investment
decisions, arranges for  the execution of  portfolio transactions and  generally
manages  each  of the  Portfolio's  investments. Set  forth  below as  an annual
percentage of average daily  net assets are the  management fees payable to  the
Adviser  quarterly by  each Portfolio  pursuant to  the terms  of the Investment
Advisory  Agreement.  The  fees  of  each  of  the  Portfolios,  which   involve
international  investments, are higher  than those of  most investment companies
because they involve international investments but the Adviser believes the fees
are   comparable    to   those    of   investment    companies   with    similar
 
                                       35
<PAGE>
objectives.  The Adviser has agreed to a reduction in the fees payable to it and
to reimburse the Portfolios, if necessary, if such fees would cause total annual
operating expenses of  the Portfolios to  exceed the maximums  set forth in  the
table below.
 
   
<TABLE>
<CAPTION>
                                                            MAXIMUM TOTAL ANNUAL
                                                                  OPERATING
                                                             EXPENSES AFTER FEE
                                            MANAGEMENT             WAIVERS
                                            ABSENT FEE      ---------------------
               PORTFOLIO                      WAIVERS       CLASS A      CLASS B
- ----------------------------------------    -----------     --------     --------
<S>                                         <C>             <C>          <C>
Global Equity                                    0.80%        1.00%        1.25%
International Equity                             0.80%        1.00%        1.25%
International Small Cap                          0.95%        1.15%         N/A
Asian Equity                                     0.80%        1.00%        1.25%
European Equity                                  0.80%        1.00%        1.25%
Japanese Equity                                  0.80%        1.00%        1.25%
Latin American                                   1.10%        1.70%        1.95%
</TABLE>
    
 
   
    The  Adviser, with  principal offices  at 1221  Avenue of  the Americas, New
York, New  York  10020,  conducts a  worldwide  portfolio  management  business,
provides  a broad  range of  portfolio management  services to  customers in the
United States and abroad. At December  31, 1995, the Adviser, together with  its
affiliated    asset   management   companies,   managed   investments   totaling
approximately $57.4 billion, including approximately $41.9 billion under  active
management  and  $15.5  billion as  Named  Fiduciary or  Fiduciary  Adviser. See
"Management of the Fund" in the Statement of Additional Information.
    
 
    PORTFOLIO  MANAGERS    The  following  individuals  have  primary  portfolio
management responsibility for the Portfolios noted below:
 
   
    GLOBAL  EQUITY PORTFOLIO  -- FRANCES  CAMPION.   Frances Campion  joined the
Adviser in January 1990 as a Global  Equity Fund Manager and is now a  Principal
of  Morgan Stanley.  Her responsibilities include  day to day  management of the
Global Equity product.  Prior to  joining the Adviser,  Ms. Campion  was a  U.S.
equity  analyst with Lombard Odler Limited  where she had responsibility for the
management of global  portfolios. Ms.  Campion has ten  years global  investment
experience. She is a graduate of University of College, Dublin.
    
 
    INTERNATIONAL EQUITY PORTFOLIO -- DOMINIC CALDECOTT.  Dominic Caldecott is a
Managing  Director and  is responsible for  research and stock  selection in the
Pacific Basin and has  been primarily responsible  for managing the  Portfolio's
assets  since its inception. He has ten years professional experience, primarily
in Tokyo, Hong Kong, and Seoul. Prior to joining Morgan Stanley, he worked  with
GT  Management  Group in  Tokyo  and Hong  Kong,  specializing in  Pacific Basin
investment management. He became a Vice  President of Morgan Stanley in 1987,  a
principal  in 1989,  and a Managing  Director in  1991. He is  responsible for a
number of Pacific Basin investment programs  for clients of Morgan Stanley.  Mr.
Caldecott is a graduate of New College, Oxford, England.
 
    INTERNATIONAL  SMALL CAP PORTFOLIO -- MARGARET NAYLOR.  Margaret Naylor is a
Principal of Morgan Stanley  and works with Dominic  Caldecott on Pacific  Basin
research  and stock selection. She joined the Adviser in March 1987 and has been
primarily responsible for managing the  Portfolio's assets since December  1992.
Prior  to joining the Adviser she spent three years at the Trade Policy Research
Centre, an independent research unit. Ms. Naylor is a graduate of the University
of York. Ms. Naylor became a Vice President of Morgan Stanley in 1993.
 
                                       36
<PAGE>
   
    ASIAN EQUITY PORTFOLIO -- EAN WAH CHIN.  Ean Wah Chin is a Managing Director
of Morgan Stanley, and is responsible  for the Adviser's regional Asia  ex-Japan
operations  based in Singapore. She has  been primarily responsible for managing
the Portfolio's assets since its inception.  Prior to joining Morgan Stanley  in
1986,  Ms. Chin spent eight  years with the Monetary  Authority of Singapore and
the Government of Singapore  Investment Corporation, where  she was a  portfolio
manager  of one of the largest portfolios in Asia. Ms. Chin was an ASEAN scholar
educated at the University of Singapore.
    
 
    EUROPEAN EQUITY PORTFOLIO -- ROBERT  SARGENT.  Robert Sargent joined  Morgan
Stanley  International in  May, 1986,  and transferred  to the  Adviser in June,
1987. Mr. Sargent is now  a Principal of Morgan  Stanley and has been  primarily
responsible for managing the Portfolio's assets since its inception. As the fund
manager with primary responsibility for continental European stock selection and
portfolio  management,  Mr.  Sargent  is  closely  involved  with  the Adviser's
fundamental research effort and  company visiting program. He  is a graduate  of
York University, Toronto, Canada.
 
    JAPANESE    EQUITY   PORTFOLIO    --   DOMINIC    CALDECOTT   AND   KUNIHIKO
SUGIO.  Information about Mr.  Caldecott is included under International  Equity
Portfolio  above. Mr. Caldecott is responsible  for research and stock selection
in the  Pacific  Basin and  has  been  primarily responsible  for  managing  the
Portfolio's  assets since  its inception. Kunihiko  Sugio joined  the Adviser in
December 1993  as  a  Vice  President  and  manages  dedicated  Japanese  equity
portfolios.  He  has been  primarily  responsible for  managing  the Portfolio's
assets since its  inception. Prior  to joining  Morgan Stanley,  he worked  with
Baring  International Investment Management, Tokyo, where  he was a Director and
fund manager. He graduated from Wakayama Kokuritsu University.
 
    LATIN AMERICAN  PORTFOLIO --  ROBERT  L. MEYER.    Robert Meyer  joined  the
Adviser  in  1989  and  is  now a  Principal  of  Morgan  Stanley,  with primary
responsibility for the Adviser's investments in all of Latin America and Israel.
He has had primary responsibility for managing the Portfolio's assets since  its
inception.  Robert is co-manager of the  Latin American Discovery Fund, Inc. and
worked previously  in the  U.S. equity  group at  the Adviser.  He was  born  in
Argentina  and has a B.A.  in Economics and Political  Science from Yale College
and a J.D. from Harvard Law School.
 
    ADMINISTRATOR.   The  Adviser also  provides  the Fund  with  administrative
services  pursuant to an  Administration Agreement. The  services provided under
the Administration Agreement are subject to the supervision of the Officers  and
Board  of Directors of the Fund and include day-to-day administration of matters
related to the  corporate existence  of the  Fund, maintenance  of its  records,
preparation  of  reports,  supervision  of  the  Fund's  arrangements  with  its
custodian, assistance in the preparation  of the Fund's registration  statements
under  federal and state  laws. The Administration  Agreement also provides that
the Administrator through its agents  will provide the Fund dividend  disbursing
and   transfer  agent  services.  For  its  services  under  the  Administration
Agreement, the Fund  pays the Adviser  a monthly  fee which on  an annual  basis
equals 0.15% of the average daily net assets of each Portfolio.
 
   
    Under  an agreement between  the Adviser and The  Chase Manhattan Bank, N.A.
("Chase"), Chase  provides certain  administrative services  to the  Fund. In  a
merger  completed on September 1, 1995, Chase succeeded to all of the rights and
obligations under the  U.S. Trust Administration  Agreement between the  Adviser
and  the United  States Trust  Company of New  York ("U.S.  Trust"), pursuant to
which U.S. Trust had  agreed to provide certain  administrative services to  the
Fund.  Pursuant  to  a  delegation  clause  in  the  U.S.  Trust  Administration
Agreement, U.S.  Trust delegated  its administration  responsibilities to  Chase
Global Funds Services Company
    
 
                                       37
<PAGE>
("CGFSC"),  formerly  known as  Mutual Funds  Service  Company, which  after the
merger with Chase is a subsidiary of Chase and will continue to provide  certain
administrative  services to the  Fund. The Adviser  supervises and monitors such
administrative services  provided  by CGFSC.  The  services provided  under  the
Administration  Agreement and the  U.S. Trust Administration  Agreement are also
subject to the supervision of the Board  of Directors of the Fund. The Board  of
Directors  of the  Fund has approved  the provision of  services described above
pursuant to  the  Administration Agreement  and  the U.S.  Trust  Administration
Agreement  as being in the best interests  of the Fund. CGFSC's business address
is  73  Tremont  Street,   Boston,  Massachusetts  02108-3913.  For   additional
information   regarding  the   Administration  Agreement,  or   the  U.S.  Trust
Administration Agreement,  see "Management  of  the Fund"  in the  Statement  of
Additional Information.
 
LOCAL ADMINISTRATORS FOR THE LATIN AMERICAN PORTFOLIO
 
    The  Portfolio has  entered into  an administration  agreement (the "Chilean
Administration Agreement") with  Bice Chileconsult Agente  de Valores S.A.  (the
"Chilean  Administrator"), a Chilean corporation,  pursuant to which the Chilean
Administrator acts as the Portfolio's  legal representative in Chile. Under  the
Chilean  Administration  Agreement, the  Chilean Administrator  performs various
services for the Portfolio, including making and obtaining all exchange  control
filings  and approvals required for the Portfolio to effect investment and other
transactions in Chile  and to remit  moneys and other  assets outside of  Chile,
obtaining  from the relevant authorities in  Chile all confirmations or consents
relating to  the tax  status of  the Portfolio  and all  tax rebates  and  other
payments   which  may  be  due  to  the  Portfolio,  and  performing  all  other
administrative duties in Chile  required by Chilean  law or Chilean  authorities
through  instructions  or regulations  to be  performed.  For its  services, the
Chilean Administrator is paid an annual fee by the Fund equal to the greater  of
0.125%  of  the  Portfolio's average  weekly  net  assets invested  in  Chile or
$20,000, paid monthly. Unless terminated by  the Fund's Board of Directors  upon
60  days' prior written notice,  or by the Chilean  Administration upon 90 days'
prior  written  notice,  the  Chilean  Administration  Agreement  will  continue
automatically from year to year.
 
    The Latin American Portfolio is required under Brazilian law to have a local
administrator  in  Brazil.  Unibanco-Uniao  (the  "Brazilian  Administrator"), a
Brazilian corporation, acts as the Portfolio's Brazilian administrator  pursuant
to  an agreement with the  Portfolio (the "Brazilian Administration Agreement").
Under  the  Brazilian  Administration  Agreement,  the  Brazilian  Administrator
performs   various  services   for  the   Portfolio,  including   effecting  the
registration of the Portfolio's foreign capital with the Central Bank of Brazil,
effecting  all  foreign  exchange   transactions  related  to  the   Portfolio's
investments  in Brazil and obtaining all approvals required for the Portfolio to
make remittances of  income and capital  gains and for  the repatriation of  the
Portfolio's  investments  pursuant  to  Brazilian  law.  For  its  services, the
Brazilian Administrator is paid an annual fee equal to 0.125% of the Portfolio's
average weekly net assets invested in Brazil, paid monthly. The principal office
of the Brazilian Administrator  is located at Avenida  Eusebio Matoso, 891,  Sao
Paulo,  S.P., Brazil. The Brazilian  Administration Agreement is terminable upon
six months' notice by either party; the Brazilian Administrator may be  replaced
only by an entity authorized to act as a joint manager of a managed portfolio of
bonds and securities under Brazilian law.
 
   
    The  Portfolio is required under Colombian law to have a local administrator
in Colombia. CitiTrust S.A. (the  "Colombian Administrator"), a Colombian  Trust
Company,  acts  as  the  Portfolio's  Colombian  administrator  pursuant  to  an
agreement with the  Portfolio (the "Colombian  Agreement"). Under the  Colombian
Agreement,  the  Columbian  Administrator  performs  various  services  for  the
Portfolio, including effecting all foreign exchange transactions related to  the
Portfolio's  foreign capital  with the Central  Bank of  Colombia, effecting all
foreign
    
 
                                       38
<PAGE>
exchange transactions related  to the  Portfolio's investments  in Colombia  and
obtaining all approvals required for the Portfolio to make remittances of income
and capital gains and the repatriation of the Portfolio's investment pursuant to
Colombian  law. For its services, the  Colombian Administrator is paid an annual
fee of $1,000 plus .20% per  transaction. The principal office of the  Colombian
Administrator  is located at Sociedad  Fiduciaria International S.A., 8-89, Piso
2, Santa Fe de Bogota, Colombia.  The Colombian Agreement is terminable upon  30
days'  notice by either party. The  Colombian Administrator may be replaced only
by an entity  authorized to act  as a joint  manager of a  managed portfolio  of
bonds and securities under Colombian law.
 
    DIRECTORS  AND OFFICERS.  Pursuant to  the Fund's Articles of Incorporation,
the Board of Directors  decides upon matters of  general policy and reviews  the
actions  of the Fund's  Adviser, Administrator and  Distributor. The officers of
the Fund conduct and supervise its daily business operations.
 
    DISTRIBUTOR.   Morgan Stanley  serves as  the exclusive  Distributor of  the
shares  of  the Fund.  Under its  Distribution Agreement  with the  Fund, Morgan
Stanley sells  shares  of each  Portfolio  upon the  terms  and at  the  current
offering  price described in this Prospectus. Morgan Stanley is not obligated to
sell any certain number of shares of any Portfolio and receives no  compensation
for its distribution services.
 
    The  Portfolios currently offer  only the classes of  shares offered by this
Prospectus. The Portfolios may in the future offer one or more classes of shares
with features, distribution expenses or  other expenses that are different  from
those of the classes currently offered.
 
    The  Fund has  adopted a Plan  of Distribution  with respect to  the Class B
shares of each Multiclass  Portfolio pursuant to Rule  12b-1 under the 1940  Act
(each,  a "Plan"). Under each Plan, the  Distributor is entitled to receive from
each Multiclass Portfolio a  distribution fee, which is  accrued daily and  paid
quarterly,  of  0.25% of  the Class  B shares'  average daily  net assets  on an
annualized basis. The distributor expects to  reallocate most of its fee to  its
investment  representatives. The Distributor may, in its discretion, voluntarily
waive from time to time all or any  portion of its distribution fee and each  of
the  Distributor and the Adviser is free  to make additional payments out of its
own assets  to  promote  the  sale  of  Fund  shares,  including  payments  that
compensate  financial  institutions  for  distribution  services  or shareholder
services.
 
    Each Plan is designed to compensate the Distributor for its services, not to
reimburse the Distributor for its expenses,  and the Distributor may retain  any
portion  of the fee that it does not expend in fulfillment of its obligations to
the Fund.
 
    EXPENSES.  Each Portfolio is responsible  for payment of certain other  fees
and  expenses  (including  legal  fees, accountant's  fees,  custodial  fees and
printing and mailing  costs) specified  in the  Administration and  Distribution
Agreements.
 
                               PURCHASE OF SHARES
 
    Class  A shares  of each  Portfolio and  Class B  shares of  each Multiclass
Portfolio may be purchased, without sales commission, at the net asset value per
share next determined after receipt of the purchase order by the Portfolio.  See
"Valuation of Shares."
 
                                       39
<PAGE>
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
 
    For  a Multiclass Portfolio  account opened on  or after January  2, 1996 (a
"New Multiclass Account"),  the minimum initial  investment and minimum  account
size  are $500,000 for Class A shares of each Portfolio and $100,000 for Class B
shares of  each  Multiclass Portfolio.  The  International Equity  Portfolio  is
currently  closed to new investors, with the exception of certain Morgan Stanley
customers.  The  minimum  initial   investment  for  Class   A  shares  of   the
International  Small Cap  Portfolio is  $500,000. Managed  Accounts may purchase
Class A  shares without  being subject  to such  minimum initial  investment  or
minimum  account  size requirements  for a  Portfolio  account. Officers  of the
Adviser and its affiliates are subject to the minimums for a Portfolio  account,
except  they may purchase Class B shares subject to a minimum initial investment
and minimum account size of $5,000 for a Multiclass Portfolio account.
 
    If the value  of a New  Multiclass Account containing  Class A shares  falls
below  $500,000  (but  remains  at or  above  $100,000)  because  of shareholder
redemption(s), the Fund will notify the  shareholders, and if the account  value
remains  below  $500,000 (but  remains at  or above  $100,000) for  a continuous
60-day period, the Class A shares in such account will convert to Class B shares
and will be subject to the distribution fee and other features applicable to the
Class B shares. The Fund,  however, will not convert Class  A shares to Class  B
shares  based solely upon changes in the  market that reduce the net asset value
of shares. Under current  tax law, conversions between  share classes are not  a
taxable event to the shareholder.
 
   
    Shares  in  a  Portfolio  account  opened  prior  to  January  2,  1996 were
designated Class A shares on January  2, 1996. Shares in a Multiclass  Portfolio
account  opened prior to January 2, 1996 (each, a "Pre-1996 Multiclass Account")
with a value  of $100,000 or  more on March  1, 1996 (a  "Grandfathered Class  A
Account")  remained Class A shares regardless of account size thereafter. Except
for shares in a Managed Account, shares in a Pre-1996 Multiclass Account with  a
value of less than $100,000 on March 1, 1996 (a "Grandfathered Class B Account")
converted to Class B shares on March 1, 1996. Grandfathered Class A Accounts and
Managed  Accounts are not subject  to conversion from Class  A shares to Class B
shares.
    
 
   
    Investors may also invest in the  Fund by purchasing shares through a  trust
department, broker, dealer, agent, financial planner, financial services firm or
investment  adviser.  An  investor  may  be  charged  an  additional  service or
transaction fee by that institution. The minimum investment levels may be waived
at the discretion  of the  Adviser for (i)  certain employees  and customers  of
Morgan  Stanley  or  its  affiliates  and  certain  trust  departments, brokers,
dealers, agents,  financial planners,  financial services  firms, or  investment
advisers  that  have  entered  into  an agreement  with  Morgan  Stanley  or its
affiliates; and (ii) retirement and deferred compensation plans and trusts  used
to  fund such  plans, including,  but not limited  to, those  defined in Section
401(a), 403(b) or  457 of the  Internal Revenue  Code of 1986,  as amended,  and
"rabbi  trusts."  The  Fund  reserves  the  right  to  modify  or  terminate the
conversion features of  the shares  as stated above  at any  time upon  60-days'
notice to shareholders.
    
 
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
 
    If  the value of  a New Multiclass  Account falls below  $100,000 because of
shareholder redemptions(s), the  Fund will  notify the shareholder,  and if  the
account  value remains below $100,000 for a continuous 60-day period, the shares
in such account are subject to redemption by the Fund and, if redeemed, the  net
asset  value of such shares will be  promptly paid to the shareholder. The Fund,
however, will not  redeem shares based  solely upon changes  in the market  that
reduce the net asset value of shares.
 
                                       40
<PAGE>
    For  purposes of redemptions by the Fund, the foregoing minimum account size
requirements do not apply to New  Multiclass Accounts containing Class B  shares
held by officers of the Adviser or its affiliates. However, if the value of such
account  held by an officer of the  Adviser or its affiliates falls below $5,000
because of shareholder redemption(s), the Fund will notify the shareholder,  and
if  the account value remains  below $5,000 for a  continuous 60-day period, the
shares in such account are subject to  redemption by the Fund and, if  redeemed,
the net asset value of such shares will be promptly paid to the shareholder.
 
    Grandfathered  Class A Accounts, Grandfathered  Class B Accounts and Managed
Accounts are not subject to involuntary redemption.
 
    If a  shareholder reduces  its total  investment in  Class A  shares of  the
International  Small Cap Portfolio to less  than $500,000, the investment may be
subject to redemption.
 
    The  Fund  reserves  the  right  to  modify  or  terminate  the  involuntary
redemption  features of  the shares  as stated above  at any  time upon 60-days'
notice to shareholders.
 
CONVERSION FROM CLASS B TO CLASS A SHARES
 
    If the value of Class B shares in a Multiclass Portfolio account  increases,
whether  due to shareholder  share purchases or market  activity, to $500,000 or
more, the Class B shares will convert to Class A shares. Under current tax  law,
such  conversion  is not  a taxable  event  to the  shareholder. Class  A shares
converted from  Class B  shares are  subject to  the same  minimum account  size
requirements  that are applicable to New  Multiclass Accounts containing Class A
shares, as stated above. The Fund reserves the right to modify or terminate this
conversion feature at any time upon 60-days' notice to shareholders.
 
INITIAL PURCHASES DIRECTLY FROM THE FUND
 
    The Fund's determination of an investor's eligibility to purchase shares  of
a  given class will  take precedence over  the investor's selection  of a class.
Assuming the investor is eligible for the  class, the Fund will select the  most
favorable class for the investor, if the investor has not done so.
 
1) BY  CHECK.   An account may  be opened  by completing and  signing an Account
   Registration Form and mailing it, together with a check ($500,000 minimum for
   Class A shares of each Portfolio and  $100,000 minimum for Class B shares  of
   each  Multiclass  Portfolio,  with  certain  exceptions  for  Morgan  Stanley
   employees and  select customers)  payable  to "Morgan  Stanley  Institutional
   Fund, Inc. -- [portfolio name]", to:
 
      Morgan Stanley Institutional Fund, Inc.
      P.O. Box 2798
      Boston, Massachusetts 02208-2798
 
 Payment  will be accepted only in  United States dollars, unless prior approval
 for payment in other currencies  is given by the  Fund. The Portfolio(s) to  be
 purchased  should be designated on the Account Registration Form. For purchases
 by check,  the  Fund is  ordinarily  credited  with Federal  Funds  within  one
 business  day. Thus your purchase of shares  by check is ordinarily credited to
 your account  at  the net  asset  value per  share  of the  relevant  Portfolio
 determined on the next business day after receipt.
 
                                       41
<PAGE>
2) BY  FEDERAL  FUNDS WIRE.   Purchases  may be  made by  having your  bank wire
   Federal Funds to the Fund's bank  account. In order to ensure prompt  receipt
   of your Federal Funds Wire, it is important that you follow these steps:
 
A.   Telephone  the Fund  (toll free: 1-800-548-7786)  and provide  us with your
    name, address,  telephone  number,  Social Security  or  Tax  Identification
    Number,  the  portfolio(s) selected,  the class  selected, the  amount being
    wired, and by  which bank.  We will  then provide  you with  a Fund  account
    number.  (Investors with existing accounts should also notify the Fund prior
    to wiring funds.)
 
B.   Instruct  your  bank to  wire  the  specified amount  to  the  Fund's  Wire
    Concentration  Bank Account (be sure  to have your bank  include the name of
    the portfolio(s)  selected,  the  class selected,  and  the  account  number
    assigned to you) as follows:
 
   
    Chase Manhattan Bank, N.A.
    One Manhattan Plaza
    New York, NY 10081-1000
    ABA #021000021
    DDA #910-2-733293
    Attn: Morgan Stanley Institutional Fund, Inc.
    Ref: (Portfolio name, your account number, your account name)
    
 
    Please call the Funds at 1-800-548-7786 prior to wiring funds.
 
C.   Complete and sign the Account Registration  Form and mail it to the address
    shown thereon.
 
  Purchase orders for shares of the  Portfolios which are received prior to  the
  regular  close of the NYSE (currently 4:00 p.m. Eastern Time) will be executed
  at the price computed  on the date  of receipt as long  as the Transfer  Agent
  receives  payment by check or  in Federal Funds prior  to the regular close of
  the NYSE on such day.
 
  Federal Funds purchase orders will be accepted only on a day on which the Fund
  and Chase (the "Custodian Bank") are open for business. Your bank may charge a
  service fee for wiring Federal Funds.
 
3) BY BANK WIRE.   The  same procedure outlined  under "By  Federal Funds  Wire"
   above  must be  followed in  purchasing shares  by bank  wire. However, money
   transferred by bank wire may or may  not be converted into Federal Funds  the
   same  day, depending on the time the  money is received and the bank handling
   the wire. Prior to such conversion, an investor's money will not be  invested
   and, therefore, will not be earning dividends. Your bank may charge a service
   fee for wiring funds.
 
ADDITIONAL INVESTMENTS
 
    You  may  add to  your account  at any  time (minimum  additional investment
$1,000 for each portfolio,  except for automatic  reinvestment of dividends  and
capital  gains  distributions for  which there  are  no minimums)  by purchasing
shares at net asset  value by mailing  a check to the  Fund (payable to  "Morgan
Stanley  Institutional Fund  -- [portfolio  name]") at  the above  address or by
wiring monies to the Custodian Bank as outlined above. It is very important that
your account name, the portfolio name and the class selected be specified in the
letter or wire to assure  proper crediting to your  account. In order to  ensure
that your wire orders are invested promptly,
 
                                       42
<PAGE>
you  are  requested  to  notify one  of  the  Fund's  representatives (toll-free
1-800-548-7786) prior to the wire  date. Additional investments will be  applied
to  purchase additional  shares in  the same  class held  by a  shareholder in a
Portfolio account.
 
OTHER PURCHASE INFORMATION
 
    The purchase price of the  Class A and Class B  shares of each Portfolio  is
the  net asset value next determined after the order is received. See "Valuation
of Shares." An order received prior to  the regular close of the New York  Stock
Exchange  ("NYSE"), which is currently 4:00  p.m. Eastern Time, will be executed
at the  price computed  on the  date of  receipt; an  order received  after  the
regular close of the NYSE will be executed at the price computed on the next day
the  NYSE is open as long as the  Transfer Agent receives payment by check or in
Federal Funds prior to the regular close of the NYSE on such day.
 
    Although the legal rights of Class A  and Class B shares will be  identical,
the  different expenses borne by  each class will result  in different net asset
values and dividends. The net  asset value of Class  B shares will generally  be
lower than the net asset value of Class A shares as a result of the distribution
expense  charged to Class B shares. It  is expected, however, that the net asset
value per share of the two classes  will tend to converge immediately after  the
recording  of dividends  which will  differ by  approximately the  amount of the
distribution expense accrual differential between the classes.
 
    In the interest  of economy and  convenience, and because  of the  operating
procedures  of the  Fund, certificates  representing shares  of the Portfolio(s)
will not be issued. All  shares purchased are confirmed  to you and credited  to
your  account on the Fund's  books maintained by the  Adviser or its agents. You
will have  the same  rights and  ownership with  respect to  such shares  as  if
certificates had been issued.
 
    To  ensure that checks are collected by the Fund, withdrawals of investments
made by check  are not presently  permitted until payment  for the purchase  has
been  received  which may  take  up to  eight business  days  after the  date of
purchase. As a condition  of this offering,  if a purchase  is cancelled due  to
nonpayment or because your check does not clear, you will be responsible for any
loss  the Fund or its  agents incur. If you are  already a shareholder, the Fund
may redeem shares from your account(s) to  reimburse the Fund or its agents  for
any  loss. In addition, you  may be prohibited or  restricted from making future
investments in the Fund.
 
    Investors may  also invest  in the  Fund by  purchasing shares  through  the
Distributor.
 
EXCESSIVE TRADING
 
    Frequent   trades  involving  either  substantial   portfolio  assets  or  a
substantial portion of your  account or accounts controlled  by you can  disrupt
management  of a portfolio and raise its expenses. Consequently, in the interest
of all the stockholders of the  Portfolios and the Portfolios' performance,  the
Fund  may in its discretion bar a  stockholder that engages in excessive trading
of shares of any class  of a portfolio from further  purchases of shares of  the
Fund  for an indefinite period. The Fund  considers excessive trading to be more
than one purchase and sale involving shares of the same class of a portfolio  of
the  Fund  within  any  120-day  period. As  an  example,  exchanging  shares of
portfolios of the Fund as follows amounts to excessive trading: exchanging Class
A shares of Portfolio A for Class A shares of Portfolio B, then exchanging Class
A shares of Portfolio B for Class  A shares of Portfolio C and again  exchanging
Class A shares of Portfolio C for Class A shares of Portfolio B within a 120-day
 
                                       43
<PAGE>
period.  Two  types  of transactions  are  exempt from  these  excessive trading
restrictions: (1) trades  exclusively between money  market portfolios; and  (2)
trades  done  in  connection  with  an asset  allocation  service,  such  as TFM
Accounts, managed or advised by MSAM and/or any of its affiliates.
 
                              REDEMPTION OF SHARES
 
    You may  withdraw all  or  any portion  of the  amount  in your  account  by
redeeming  shares at any time. Please note  that purchases made by check are not
permitted to be redeemed until payment of the purchase has been collected, which
may take up to eight business days after purchase. The Fund will redeem Class  A
shares  of each Portfolio or Class B  shares of each Multiclass Portfolio at the
next determined net asset value of shares of the applicable class. On days  that
both the NYSE and the Custodian Bank are open for business, the net asset values
per  share of  each of  the Portfolios  are determined  at the  regular close of
trading of the NYSE (currently 4:00 p.m. Eastern Time). Shares of each Portfolio
may be redeemed by mail or telephone. No charge is made for redemptions,  except
for  the imposition  of the 1%  transaction fee described  under "Fund Expenses"
above, which may  be assessed in  connection with redemptions  of shares of  the
International  Small Cap Portfolio. Any redemption  proceeds may be more or less
than the purchase price  of your shares depending  on, among other factors,  the
market value of the investment securities held by a Portfolio.
 
BY MAIL
 
    Each  Portfolio will redeem its  Class A or Class B  shares at the net asset
value determined on the date the request is received, if the request is received
in "good order" before  the regular close  of the NYSE.  Your request should  be
addressed  to Morgan  Stanley Institutional Fund,  Inc., P.O.  Box 2798, Boston,
Massachusetts 02208-2798, except that deliveries by overnight courier should  be
addressed  to Morgan  Stanley Institutional Fund,  Inc., c/o  Chase Global Funds
Services Company, 73 Tremont Street, Boston, Massachusetts 02108-3913.
 
    "Good order"  means that  the  request to  redeem  shares must  include  the
following documentation:
 
        (a)   A letter of instruction or a stock assignment specifying the class
    and number  of  shares  or dollar  amount  to  be redeemed,  signed  by  all
    registered  owners  of the  shares  in the  exact  names in  which  they are
    registered;
 
        (b)  Any  required   signature  guarantees   (see  "Further   Redemption
    Information" below); and
 
        (c)    Other supporting  legal documents,  if required,  in the  case of
    estates, trusts,  guardianships, custodianships,  corporations, pension  and
    profit sharing plans and other organizations.
 
    Shareholders who are uncertain of requirements for redemption should consult
with a Morgan Stanley Institutional Fund representative.
 
BY TELEPHONE
 
    Provided  you have previously elected the Telephone Redemption Option on the
Account Registration  Form, you  can  request a  redemption  of your  shares  by
calling  the Fund  and requesting  the redemption proceeds  be mailed  to you or
wired to your bank.  Please contact one of  Morgan Stanley Institutional  Fund's
representatives  for further details. In times of drastic market conditions, the
telephone redemption option  may be  difficult to implement.  If you  experience
difficulty in making a telephone redemption, your request may be made by regular
mail  or express  mail and it  will be implemented  at the net  asset value next
determined after it is received.
 
                                       44
<PAGE>
Redemption requests sent to the Fund through express mail must be mailed to  the
address  of the  Dividend Disbursing  and Transfer  Agent listed  under "General
Information". The Fund and the Fund's transfer agent (the "Transfer Agent") will
employ reasonable procedures  to confirm that  the instructions communicated  by
telephone are genuine. Redemption requests sent to the Fund through express mail
must  be mailed  to the  address of the  Dividend Disbursing  and Transfer Agent
listed under  "General  Information".  These procedures  include  requiring  the
investor  to provide certain personal identification  information at the time an
account  is  opened  and  prior  to  effecting  each  transaction  requested  by
telephone.  In addition, all telephone transaction requests will be recorded and
investors may be required to provide additional telecopied written  instructions
regarding  transaction requests. Neither the Fund nor the Transfer Agent will be
responsible for any loss, liability, cost or expense for following  instructions
received by telephone that either of them reasonably believes to be genuine.
 
    To  change the commercial  bank or account  designated to receive redemption
proceeds, a written  request must  be sent  to the  Fund at  the address  above.
Requests  to change the bank  or account must be  signed by each shareholder and
each signature must be guaranteed.
 
FURTHER REDEMPTION INFORMATION
 
    Normally the  Fund will  make payment  for all  shares redeemed  within  one
business  day of receipt  of the request, but  in no event  will payment be made
more than  seven days  after receipt  of  a redemption  request in  good  order.
However,  payments to investors  redeeming shares which  were purchased by check
will not be made until  payment for the purchase  has been collected, which  may
take up to eight days after the date of purchase. The Fund may suspend the right
of  redemption or postpone the date upon which redemptions are effected at times
when the NYSE is closed, or  under any emergency circumstances as determined  by
the Securities and Exchange Commission (the "Commission").
 
    If  the Board of  Directors determines that  it would be  detrimental to the
best interests of  the remaining  shareholders of  a Portfolio  to make  payment
wholly  or partly in cash, the Fund may  pay the redemption proceeds in whole or
in part by a distribution in-kind of  securities held by a Portfolio in lieu  of
cash    in    conformity   with    applicable    rules   of    the   Commission.
Distributions-in-kind will be made  in readily marketable securities.  Investors
may  incur brokerage charges on the sale  of portfolio securities so received in
payment of redemptions.
 
    To protect  your account,  the Fund  and its  agents from  fraud,  signature
guarantees  are required for  certain redemptions to verify  the identity of the
person who has  authorized a redemption  from your account.  Please contact  the
Fund  for further  information. See "Redemption  of Shares" in  the Statement of
Additional Information.
 
                              SHAREHOLDER SERVICES
 
EXCHANGE FEATURES
 
    You may exchange  shares that you  own in  any Portfolio for  shares of  any
other  available portfolio(s) of  the Fund (other  than the International Equity
Portfolio, which is  closed to  new investors). In  exchanging for  shares of  a
portfolio  with more  than one  class, the  class of  shares you  receive in the
exchange will be determined in the same  manner as any other purchase of  shares
and  will not  be based  on the  class of  shares surrendered  for the exchange.
Consequently, the same minimum initial  investment and minimum account size  for
determining  the  class  of shares  received  in  the exchange  will  apply. See
"Purchase of  Shares." Shares  of the  portfolios may  be exchanged  by mail  or
telephone.  The privilege to exchange shares  by telephone is automatic and made
available
 
                                       45
<PAGE>
without shareholder election. Before you make  an exchange, you should read  the
prospectus  of the portfolio(s) in which you seek to invest. Because an exchange
transaction is treated as a redemption followed by a purchase, an exchange would
be considered a  taxable event  for shareholders  subject to  tax. The  exchange
privilege  is only available with respect  to portfolios that are registered for
sale in  a shareholder's  state  of residence.  The  exchange privilege  may  be
modified  or  terminated  by  the  Fund at  any  time  upon  60-days'  notice to
shareholders.
 
BY MAIL
 
    In order to  exchange shares  by mail, you  should include  in the  exchange
request  the name, class of shares and account number of your current Portfolio,
the name(s) of the portfolio(s) and class(es) of shares into which you intend to
exchange shares, and the signatures of all registered account holders. Send  the
exchange  request to  Morgan Stanley  Institutional Fund,  Inc., P.O.  Box 2798,
Boston, Massachusetts 02208-2798.
 
BY TELEPHONE
 
    When exchanging shares by  telephone, have ready the  name, class of  shares
and  account number of your current Portfolio, the name(s) of the portfolio into
which you intend  to exchange shares,  your Social Security  number or Tax  I.D.
number,  and  your account  address. Requests  for telephone  exchanges received
prior to 4:00 p.m. (Eastern  Time) are processed at  the close of business  that
same  day  based on  the  net asset  value of  the  class(es) of  the portfolios
involved in the exchange of shares  at the close of business. Requests  received
after  4:00 p.m. (Eastern Time) are processed the next business day based on the
net asset value determined at the close of business on such day. For  additional
information   regarding  responsibility  for   the  authenticity  of  telephoned
instructions, see "Redemption of Shares -- By Telephone" above.
 
TRANSFER OF REGISTRATION
 
    You may transfer  the registration  of any of  your Fund  shares to  another
person  by writing  to Morgan Stanley  Institutional Fund, Inc.,  P.O. Box 2798,
Boston, Massachusetts 02208-2798.  As in  the case of  redemptions, the  written
request  must  be  received in  good  order  before any  transfer  can  be made.
Transferring the  registration of  shares  may affect  the eligibility  of  your
account  for a given class  of the Portfolio's shares  may result in involuntary
conversion or redemption of your shares. See "Purchase of Shares" above.
 
                              VALUATION OF SHARES
 
    The net asset value per share of a class of shares of each of the Portfolios
is determined by dividing the total market value of the Portfolio's  investments
and  other assets attributable to such  class, less any liabilities attributable
to such class, by the  total number of outstanding shares  of each class of  the
Portfolio.  Net  asset value  is  calculated separately  for  each class  of the
Portfolios. Net asset value per share is  determined as of the regular close  of
the  NYSE on each day  that the NYSE is open  for business. Price information on
listed securities is  taken from the  exchange where the  security is  primarily
traded.  Securities  listed  on  a U.S.  securities  exchange  for  which market
quotations are available are valued at the last quoted sale price on the day the
valuation is made. Securities listed on  a foreign exchange are valued at  their
closing  price.  Unlisted securities  and listed  securities  not traded  on the
valuation date for which market quotations are not readily available are  valued
at  a price within a  range not exceeding the current  asked price nor less than
the current bid price. The current bid and asked prices are determined based  on
the  average bid  and asked  prices quoted on  such valuation  date by reputable
brokers.
 
                                       46
<PAGE>
    Bonds and other fixed income securities are valued according to the broadest
and most representative  market, which will  ordinarily be the  over-the-counter
market.  Net asset value includes interest  on fixed income securities, which is
accrued daily.  In addition,  bonds and  other fixed  income securities  may  be
valued on the basis of prices provided by a pricing service when such prices are
believed  to  reflect  the fair  market  value  of such  securities.  The prices
provided by a pricing service are determined without regard to bid or last  sale
prices  but take  into account institutional  size trading in  similar groups of
securities and any developments related  to the specific securities.  Securities
not  priced in this manner are valued at the most recently quoted bid price, or,
when securities exchange valuations are used, at the latest quoted sale price on
the day of valuation. If there is  no such reported sale, the latest quoted  bid
price will be used. Securities purchased with remaining maturities of 60 days or
less are valued at amortized cost, if it approximates market value. In the event
that  amortized  cost  does  not  approximate  market  value,  market  prices as
determined above will be used.
 
    The value of other assets and securities for which no quotations are readily
available (including  restricted  and  unlisted foreign  securities)  and  those
securities  for which it is inappropriate  to determine the prices in accordance
with the above-stated  procedures are  determined in  good faith  at fair  value
using  methods determined by the Board of Directors. For purposes of calculating
net asset value  per share, all  assets and liabilities  initially expressed  in
foreign  currencies will be translated into U.S.  dollars at the mean of the bid
price and asked price for such currencies against the U.S. dollar last quoted by
any major bank.
 
    Although the legal rights of Class A  and Class B shares will be  identical,
the  different expenses borne by  each class will result  in different net asset
values and dividends for the class.  Dividends will differ by approximately  the
amount  of the distribution expense accrual  differential among the classes. The
net asset value of  Class B shares  will generally be lower  than the net  asset
value  of the Class A shares as a result of the distribution expenses charged to
Class B shares.
 
                            PERFORMANCE INFORMATION
 
    The Fund may from time to time  advertise the "total return" for each  class
of  a Portfolio.  THESE FIGURES  ARE BASED  ON HISTORICAL  EARNINGS AND  ARE NOT
INTENDED TO INDICATE FUTURE PERFORMANCE.
 
    Each of the  Portfolios may  advertise "total  return" which  shows what  an
investment  in a class of a Portfolio  would have earned over a specified period
of time (such as  one, five or  ten years) assuming  that all distributions  and
dividends by the Portfolio were reinvested in the same class on the reinvestment
dates  during the period. Total return does not take into account any federal or
state income taxes  that may  be payable on  dividends and  distributions or  on
redemption.  The Fund  may also  include comparative  performance information in
advertising or  marketing the  Portfolios' shares,  including data  from  Lipper
Analytical  Services, Inc.,  other industry  publications, business periodicals,
rating services and market indices.
 
    The performance figures  for Class  B shares  will generally  be lower  than
those  for Class  A shares because  of the  distribution fee charged  to Class B
shares.
 
                                       47
<PAGE>
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
 
    All income dividends and capital gains  distributions for a class of  shares
will automatically be reinvested in additional shares at net asset value, except
that,  upon written notice to the Fund or by checking off the appropriate box in
the Distribution Option Section on the Account Registration Form, a  shareholder
may elect to receive income dividends and capital gains distributions in cash.
 
    Each Portfolio expects to distribute substantially all of its net investment
income  in  the form  of annual  dividends.  Net realized  gains, if  any, after
reduction for  any available  tax loss  carryforwards will  also be  distributed
annually.  Confirmations of the purchase of  shares of the Portfolio through the
automatic reinvestment of income dividends and capital gains distributions  will
be  provided, pursuant  to Rule 10b-10(b)  under the Securities  Exchange Act of
1934, as amended, on the next  monthly client statement following such  purchase
of  shares. Consequently, confirmation of such purchases will not be provided at
the time of completion of such purchases as might otherwise be required by  Rule
10b-10. Net capital gains, if any, will be distributed annually.
 
    Undistributed  net investment income is included in a Portfolio's net assets
for the purpose  of calculating  net asset value  per share.  Therefore, on  the
"ex-dividend"  date, the net asset value  per share excludes the dividend (i.e.,
is reduced by  the per  share amount of  the dividend).  Dividends paid  shortly
after  the purchase  of shares by  an investor,  although in effect  a return of
capital, are taxable to shareholders subject to income tax.
 
    Because of  the  distribution  fee  and  any  other  expenses  that  may  be
attributable  to the  Class B  shares, the  net income  attributable to  and the
dividends payable  on  Class  B  shares  will  be  lower  than  the  net  income
attributable  to and the dividends  payable on Class A  shares. As a result, the
net asset value per share of the classes of the Portfolios will differ at times.
Expenses of the  Portfolios allocated to  a particular class  of shares  thereof
will be borne on a pro rata basis by each outstanding share of that class.
 
                                     TAXES
 
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
 
    No  attempt has been made to present  a detailed explanation of the federal,
state, or local income  tax treatment of the  Portfolios or their  shareholders.
Accordingly,  shareholders  are urged  to consult  their tax  advisers regarding
specific questions as to federal, state and local income taxes.
 
    Each Portfolio  is treated  as  a separate  entity  for federal  income  tax
purposes  and is not  combined with the Fund's  other Portfolios. Each Portfolio
intends to qualify for the  special tax treatment afforded regulated  investment
companies  under Subchapter M of  the Internal Revenue Code  of 1986, as amended
(the "Code"), so that the  Portfolio will be relieved  of federal income tax  on
that  part of its net investment income and net capital gain that is distributed
to shareholders.
 
   
    Each Portfolio distributes  substantially all of  its net investment  income
(including,  for  this purpose,  net short-term  capital gain)  to shareholders.
Dividends from a Portfolio's net  investment income are taxable to  shareholders
as  ordinary  income, whether  received in  cash or  in additional  shares. Such
dividends  paid   by  a   Portfolio   will  generally   qualify  for   the   70%
dividends-received  deduction for corporate  shareholders only to  the extent of
the aggregate qualifying  dividend income  received by the  Portfolio from  U.S.
corporations. Each Portfolio will report annually to its shareholders the amount
of dividend income qualifying for such treatment.
    
 
                                       48
<PAGE>
   
    Distributions  of net capital gain (the excess of net long-term capital gain
over net  short-term capital  loss)  are taxable  to shareholders  as  long-term
capital  gain, regardless of how long  shareholders have held their shares. Each
Portfolio sends reports annually to its  shareholders of the federal income  tax
status of all distributions made during the preceding year.
    
 
   
    Each   Portfolio  intends   to  make  sufficient   distributions  or  deemed
distributions of its ordinary income and capital gain net income (the excess  of
short-term  and long-term  capital gains  over short-term  and long-term capital
losses), including any available capital loss carryforwards, prior to the end of
each calendar year to avoid liability for federal excise tax.
    
 
   
    Dividends and  other  distributions  declared by  a  Portfolio  in  October,
November or December of any year and payable to shareholders of record on a date
in  such month will be deemed to have been paid by the Portfolio and received by
the shareholders in that year if the distributions are paid by the Portfolio  at
any time during the following January.
    
 
   
    The  sale, exchange or  redemption of shares  may result in  taxable gain or
loss to the selling, exchanging or redeeming shareholder, depending upon whether
the fair market value of the sale, exchange or redemption proceeds exceeds or is
less than the Shareholder's  adjusted basis in the  sold, exchanged or  redeemed
shares. If capital gain distributions have been made with respect to shares that
are  sold at a loss  after being held for  six months or less,  then the loss is
treated as  a  long-term  capital  loss  to  the  extent  of  the  capital  gain
distributions.
    
   
    The  conversion of Class A shares to Class  B shares should not be a taxable
event to the shareholder.
    
 
   
    Shareholders are urged  to consult  with their tax  advisors concerning  the
application of state and local income taxes to investments in a Portfolio, which
may differ from the federal income tax consequences described above.
    
 
   
    Investment  income  received  by  a Portfolio  from  sources  within foreign
countries may be subject to foreign income taxes withheld at the source. To  the
extent  that a Portfolio  is liable for  foreign income taxes  so withheld, each
Portfolio intends to operate so as to meet the requirements of the Code to  pass
through  to the shareholders credit for foreign income taxes paid. Although each
Portfolio intends to  meet Code  requirements to  pass through  credit for  such
taxes, there can be no assurance that each Portfolio will be able to do so.
    
 
   
    THE   TAX  DISCUSSION  SET  FORTH  ABOVE  IS  INCLUDED  HEREIN  FOR  GENERAL
INFORMATION ONLY. PROSPECTIVE  INVESTORS SHOULD CONSULT  THEIR OWN TAX  ADVISERS
WITH RESPECT TO THE TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN A PORTFOLIO.
    
 
                             PORTFOLIO TRANSACTIONS
 
    The  Investment  Advisory Agreement  authorizes  the Adviser  to  select the
brokers or  dealers that  will execute  the purchases  and sales  of  investment
securities  for each of the Fund's Portfolios and directs the Adviser to use its
best efforts to  obtain the best  available price and  most favorable  execution
with respect to all transactions for the Portfolios. The Fund has authorized the
Adviser to pay higher commissions in recognition of brokerage services which, in
the  opinion  of  the  Adviser,  are necessary  for  the  achievement  of better
execution, provided the Adviser believes this to be in the best interest of  the
Fund.
 
                                       49
<PAGE>
    Since shares of the Portfolios are not marketed through intermediary brokers
or  dealers, it is  not the Fund's  practice to allocate  brokerage or principal
business on the basis of sales of  shares which may be made through such  firms.
However,  the Adviser may  place portfolio orders  with qualified broker-dealers
who recommend the Portfolios or who act  as agents in the purchase of shares  of
the Portfolios for their clients.
 
    In  purchasing  and selling  securities for  a Portfolio,  it is  the Fund's
policy to seek to obtain quality execution at the most favorable prices, through
responsible  broker-dealers.  In   selecting  broker-dealers   to  execute   the
securities  transactions for the Portfolios, consideration will be given to such
factors as the price of the security,  the rate of the commission, the size  and
difficulty  of  the  order,  the  reliability,  integrity,  financial condition,
general execution and operational capabilities of competing broker-dealers,  and
the  brokerage  and  research services  which  they  provide to  the  Fund. Some
securities considered for investment by a Portfolio may also be appropriate  for
other  clients  served  by  the  Adviser.  If  purchase  or  sale  of securities
consistent with the investment policies of a Portfolio and one or more of  these
other  clients served by  the Adviser is  considered at or  about the same time,
transactions in such securities will be  allocated among the Portfolio and  such
other  clients in a manner  deemed fair and reasonable  by the Adviser. Although
there is  no specified  formula for  allocating such  transactions, the  various
allocation methods used by the Adviser, and the results of such allocations, are
subject to periodic review by the Fund's Board of Directors.
 
    Subject to the overriding objective of obtaining the best possible execution
of  orders, the Adviser may allocate a portion of the Fund's portfolio brokerage
transactions to Morgan Stanley or broker affiliates of Morgan Stanley. In  order
for  Morgan Stanley or  its affiliates to effect  any portfolio transactions for
the Portfolios, the commissions, fees  or other remuneration received by  Morgan
Stanley  or  such  affiliates  must  be  reasonable  and  fair  compared  to the
commissions, fees or other remuneration paid to other brokers in connection with
comparable transactions involving similar securities being purchased or sold  on
a securities exchange during a comparable period of time. Furthermore, the Board
of  Directors of the Fund,  including a majority of  those Directors who are not
"interested persons," as defined in the 1940 Act, have adopted procedures  which
are  reasonably  designed  to  provide  that  any  commissions,  fees  or  other
remuneration paid to Morgan Stanley or  such affiliates are consistent with  the
foregoing standard.
 
    Portfolio  securities will not be  purchased from or through,  or sold to or
through, the Adviser or Morgan Stanley  or any "affiliated persons," as  defined
in  the 1940 Act, of Morgan Stanley when such entities are acting as principals,
except to the extent permitted by law.
 
                              GENERAL INFORMATION
 
DESCRIPTION OF COMMON STOCK
 
    The Fund  was organized  as a  Maryland corporation  on June  16, 1988.  The
Articles  of Incorporation, as amended and restated, permit the Fund to issue up
to 34 billion shares of common stock,  with $.001 par value per share.  Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number  of shares the  Fund is authorized  to issue without  the approval of the
shareholders of the  Fund. Subject  to the  notice period  to shareholders  with
respect  to shares held by shareholders, the Board of Directors has the power to
designate one or  more classes of  shares of  common stock and  to classify  and
reclassify any unissued shares with
 
                                       50
<PAGE>
respect  to  such classes.  The shares  of  common stock  of each  Portfolio are
currently classified  into two  classes, the  Class  A shares  and the  Class  B
shares, except for the International Small Cap, Money Market and Municipal Money
Market Portfolios, which only offer Class A shares.
 
   
    The   shares  of   each  Portfolio,  when   issued,  will   be  fully  paid,
nonassessable, fully transferable and  redeemable at the  option of the  holder.
The  shares have no preference as to conversion, exchange, dividends, retirement
or other features and have no  pre-emptive rights. The shares of each  Portfolio
have non-cumulative rights, which means that the holders of more than 50% of the
shares  voting for the election of Directors  can elect 100% of the Directors if
they choose  to do  so.  Persons or  organizations owning  25%  or more  of  the
outstanding  shares of a Portfolio  may be presumed to  "control" (as defined in
the 1940 Act) such Portfolio.  Under Maryland law, the  Fund is not required  to
hold  an annual meeting of  its shareholders unless required  to do so under the
1940 Act.
    
 
REPORTS TO SHAREHOLDERS
 
    The Fund will send to its  shareholders annual and semi-annual reports;  the
financial  statements  appearing in  annual reports  are audited  by independent
accountants. Monthly unaudited portfolio  data is also  available from the  Fund
upon request.
 
    In  addition, the Adviser or its agent, as Transfer Agent, will send to each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
 
CUSTODIAN
 
    As of September  1, 1995,  domestic securities and  cash are  held by  Chase
which  replaced U.S.  Trust as  the Fund's domestic  custodian. Chase  is not an
affiliate of  the Adviser  or  the Distributor.  Morgan Stanley  Trust  Company,
Brooklyn,  New York ("MSTC"),  an affiliate of the  Adviser and the Distributor,
acts as the Fund's custodian for  foreign assets held outside the United  States
and  employs subcustodians  approved by  the Board of  Directors of  the Fund in
accordance with regulations of  the Securities and  Exchange Commission for  the
purpose  of providing  custodial services  for such  assets. MSTC  may also hold
certain domestic assets for  the Fund. For more  information on the  custodians,
see "General Information -- Custody Arrangements" in the Statement of Additional
Information.
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
    Chase   Global   Funds  Services   Company,   73  Tremont   Street,  Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
 
INDEPENDENT ACCOUNTANTS
 
    Price Waterhouse  LLP serves  as independent  accountants for  the Fund  and
audits its annual financial statements.
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       51
<PAGE>
<TABLE>
<CAPTION>
   MORGAN STANLEY INSTITUTIONAL FUND, INC.
           GLOBAL EQUITY, INTERNATIONAL EQUITY, INTERNATIONAL SMALL CAP, 
           ASIAN EQUITY, EUROPEAN EQUITY, JAPANESE EQUITY 
           AND LATIN AMERICAN PORTFOLIOS
           P.O. BOX 2798, BOSTON, MA 02208-2798


- ---------------------------------------------------------------------------------------------------------------

                           ACCOUNT REGISTRATION FORM
- ---------------------------------------------------------------------------------------------------------------
<S>                        <C>
ACCOUNT INFORMATION        If you need assistance in filling out this form     
Fill in where applicable   for the Morgan Stanley Institutional Fund, please   
                           contact your Morgan Stanley representative or call  
                           us toll free 1-(800)-548-7786. Please print all     
                           items except signature, and mail to the Fund at the
                           address above.

- ---------------------------------------------------------------------------------------------------------------
A)  REGISTRATION
    1. INDIVIDUAL            1. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
                                 First Name           Initial              Last Name
    2. JOINT TENANTS         2. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       (RIGHTS OF                First Name           Initial              Last Name
       SURVIVORSHIP            / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       PRESUMED UNLESS           First Name           Initial              Last Name
       TENANCY IN COMMON 
       IS INDICATED)      
- ---------------------------------------------------------------------------------------------------------------
    3. CORPORATIONS,        3.  / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       TRUSTS AND OTHERS       
       Please call the          / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       Fund for additional
       documents that may       / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       be required to set 
       up account and to 
       authorize transactions.
                                Type of / / INCORPORATED / / UNINCORPORATED / / PARTNERSHIP / / UNIFORM GIFT/TRANSFER TO MINOR 
                                Registration:                 ASSOCIATION                   (ONLY ONE CUSTODIAN AND MINOR PERMITTED)


                                / / TRUST __________________________________     / / OTHER (Specify) ______________________________
- ---------------------------------------------------------------------------------------------------------------
B)  MAILING ADDRESS         Street or P.O. Box / / / / / / / / / / / / / / / / / / / / / / / / / / / /

    Please fill in 
    completely, including   City / / / / / / / / / / / / / State / / / Zip / / / / / /-/ / / / / / / / 
    telephone number(s).
                            Home                                   Business
                            Telephone No./ / / /-/ / / /-/ / / / / Telephone No./ / / /-/ / / /-/ / / /
                            / / United States  / / Resident  / /Non-Resident Alien:
                                Citizen            Alien        Indicate Country of Residence _________
- ---------------------------------------------------------------------------------------------------------------
C)  TAXPAYER                PART 1. Enter your Taxpayer         C) IMPORTANT TAX INFORMATION 
    IDENTIFICATION          Identification Number. For most          You (as a payee) are required by
    NUMBER                  individual taxpayers, this is your     law to provide us (as payer) with
    If the account is in    Social Security Number.                your correct Taxpayer Identification
    more than one name,     TAXPAYER IDENTIFICATION NUMBER         Number. Accounts that have a missing
    CIRCLE THE NAME OF THE    / / / /-/ / / / / / / / /            or incorrect Taxpayer Identification
    PERSON WHOSE TAXPAYER               OR                         Number will be subject to backup
    IDENTIFICATION NUMBER       SOCIAL SECURITY NUMBER             withholding at a 31% rate on dividends,
    IS PROVIDED IN SECTION    / / / /-/ / /-/ / / / /              distributions and other payments.
    A) ABOVE. If no name      PART 2. BACKUP WITHHOLDING           If you have not provided us with
    is circled, the number    / / Check this box if you are        your correct taxpayer identification
    will be considered to be  NOT subject to Backup                number, you may be subject to 
    that of the last name     Withholding under the                a $50 penalty imposed by the Internal
    listed. For Custodian     provisions of Section                Revenue Service.
    account of a minor        3406(a)(1)(C) of the Internal          Backup withholding is not an
    (Uniform Gifts/Transfers  Revenue Code.                        additional tax; the tax liability of
    to Minor Acts), give the                                       persons subject to backup withholding
    Social Security Number                                         will be reduced by the amount of tax
    of the minor.                                                  withheld. If withholding results in
                                                                   an overpayment of taxes, a refund 
                                                                   may be obtained.
                                                                     You may be notified
                                                                   that you are subject to backup 
                                                                   withholding under Section 3406(a)(1)(C)
                                                                   of the Internal Revenue Code because you
                                                                   have underreported interest or dividends
                                                                   or you were required to but failed to
                                                                   file a return which would have included a
                                                                   reportable interest or dividend payment. IF
                                                                   YOU HAVE NOT BEEN SO NOTIFIED, CHECK THE
                                                                   BOX IN PART 2 AT LEFT.

- ---------------------------------------------------------------------------------------------------------------

D)  PORTFOLIO AND          For Purchase of the following Portfolio(s):     
    CLASS SECTION          GLOBAL EQUITY PORTFOLIO                     / / Class A Shares $____ / / Class B Shares $____
    (Class A shares        INTERNATIONAL SMALL CAP PORTFOLIO           / / Class A Shares $____ / / Class B Shares $____
    minimum $500,000       EUROPEAN EQUITY PORTFOLIO                   / / Class A Shares $____ / / Class B Shares $____
    for each Portfolio     LATIN AMERICAN PORTFOLIO                    / / Class A Shares $____ / / Class B Shares $____
    and Class B shares     INTERNATIONAL EQUITY PORTFOLIO              / / Class A Shares $____ / / Class B Shares $____
    minimum $100,000 for   ASIAN EQUITY PORTFOLIO                      / / Class A Shares $____ / / Class B Shares $____
    the Global Equity,     JAPANESE EQUITY PORTFOLIO                   / / Class A Shares $____ / / Class B Shares $____
    International Equity,                                              Total Initial Investment $_____________
    Asian Equity,
    European Equity,
    Japenese Equity and
    Latin American Equity
    Portfolios). Please
    indicate Portfolio,
    class and amount.

- ---------------------------------------------------------------------------------------------------------------

E)  METHOD OF   Payment by:
    INVESTMENT  / / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND, INC.--PORTFOLIO NAME)
     Please
    indicate
    portfolio
    manner of   / / Exchange $____________ From________________ / / / / / / / / / / /-/ /
    payment.                                Name of Portfolio          Account No.

               / / Account previously established by: / / Phone exchange / / Wire on_____/ / / / / / / / / / / /-/ /
                                                                                    Date         Account No.   (Check
                                                                              (Previously assigned by the Fund) Digit)


 
<PAGE>

- ---------------------------------------------------------------------------------------------------------------

F)  DISTRIBUTION                                       Income dividends and capital gains distributions (if any)  to
    OPTION                                             be reinvested in additional shares unless either box below is
                                                       checked.

                                                       / / Income dividends to be paid in cash, capital
                                                           gains distributions (if any) in shares.

                                                      / /  Income dividends and capital gains distributions
                                                           (if any) to be paid in cash.

- ---------------------------------------------------------------------------------------------------------------


G)  TELEPHONE REDEMPTION         / / I/we hereby authorize the Fund and its      ______________________    ________________
    AND EXCHANGE OPTION              agents to honor any telephone requests      Name of COMMERCIAL Bank   Bank Account No.
    Please select at time of         to wire redemption proceeds to the            (Not Savings Bank)
    initial application if you       commercial bank indicated at right and/or                             ________________
    wish to redeem shares or         mail redemption proceeds to the name and                                Bank ABA No.
    exchange shares by telephone.    address in which my/our fund account is
    A SIGNATURE GUARANTEE IS         registered if such requests are believed
    REQUIRED IF BANK ACCOUNT IS      to be authentic.                           _________________________________________________
    NOT REGISTERED IDENTICALLY
    TO YOUR FUND ACCOUNT.        THE FUND AND THE FUND'S TRANSFER AGENT WILL    Name(s) in which your BANK Account is Established
                                 EMPLOY REASONABLE PROCEDURES TO CONFIRM THAT
                                 INSTRUCTIONS COMMUNICATED BY TELEPHONE ARE     _________________________________________________
    TELEPHONE REQUESTS FOR       GENUINE. THESE PROCEDURES INCLUDE REQUIRING                 Bank's Street Address
    REDEMPTIONS OR EXCHANGE      THE INVESTOR TO PROVIDE CERTAIN PERSONAL
    WILL NOT BE HONORED UNLESS   IDENTIFICATION INFORMATION AT THE TIME AN      _________________________________________________
    THE BOX IS CHECKED.          ACCOUNT IS OPENED AND PRIOR TO EFFECTING EACH  City                    State                Zip
                                 TRANSACTION REQUESTED BY TELEPHONE. IN ADDITION,
                                 ALL TELEPHONE TRANSACTION REQUESTS WILL BE RECORDED
                                 AND INVESTORS MAY BE REQUIRED TO PROVIDE ADDITIONAL
                                 TELECOPIED WRITTEN INSTRUCTIONS OF TRANSACTION
                                 REQUESTS. NEITHER THE FUND NOR THE TRANSFER AGENT WILL
                                 BE RESPONSIBLE FOR ANY LOSS, LIABILITY, COST OR EXPENSE
                                 FOR FOLLOWING INSTRUCTIONS RECEIVED BY TELEPHONE THAT
                                 IT REASONABLY BELIEVES TO BE GENUINE.


- ---------------------------------------------------------------------------------------------------------------

H)  INTERESTED PARTY
    OPTION
    In addition to the account   _________________________________________________________________
    statement sent to my/our                                 Name
    registered address, I/we     _________________________________________________________________
    hereby authorize the fund    
    to mail duplicate            _________________________________________________________________
    statements to the name and                              Address
    address provided at right.
                                 _________________________________________________________________
                                  City                      State                     Zip Code

- ---------------------------------------------------------------------------------------------------------------

I)  DEALER 
    INFORMATION                  _______________________  _______________________________  ___________
                                 Representative Name          Representative No.             Branch No.

- ---------------------------------------------------------------------------------------------------------------

J)  SIGNATURE OF        The undersigned certify  that I/we  have full  authority and  legal
    ALL HOLDERS         capacity  to purchase and redeem shares of the Fund and affirm that I/we
    AND TAXPAYER        have received a current Prospectus  of the Morgan Stanley  Institutional
    CERTIFICATION       Fund,  Inc. and agree to  be bound by its  terms. UNDER THE PENALTIES OF
    Sign Here >         PERJURY, I/WE CERTIFY THAT THE INFORMATION PROVIDED IN SECTION C)
                        ABOVE IS TRUE, CORRECT AND COMPLETE.

                        (X)                                 (X)
                        __________________________________  ______________________________________
                        Signature                Date       Signature                  Date

                        (X)                                 (X)
                        __________________________________  ______________________________________
                        Signature                Date       Signature                  Date


- ---------------------------------------------------------------------------------------------------------------

</TABLE>

<PAGE>






                 (This page has been left blank intentionally.)

<PAGE>
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
 
  NO  DEALER, SALES  REPRESENTATIVE OR ANY  OTHER PERSON HAS  BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE  CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS  HAVING BEEN AUTHORIZED BY THE FUND  OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF  THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION  TO
ANY  PERSON TO WHOM  IT IS UNLAWFUL TO  MAKE SUCH OFFER  OR SOLICITATION IN SUCH
JURISDICTION.
 
                           --------------------------
 
                               TABLE OF CONTENTS
 
   
<TABLE>
<S>                                                 <C>
                                                    PAGE
                                                    ----
Fund Expenses.....................................    2
Financial Highlights..............................    6
Prospectus Summary................................   14
Investment Objectives and Policies................   18
Additional Investment Information.................   26
Investment Limitations............................   35
Management of the Fund............................   35
Purchase of Shares................................   40
Redemption of Shares..............................   44
Shareholder Services..............................   46
Valuation of Shares...............................   46
Performance Information...........................   47
Dividends and Capital Gains Distributions.........   48
Taxes.............................................   48
Portfolio Transactions............................   50
General Information...............................   51
Account Registration Form
</TABLE>
    
 
                            GLOBAL EQUITY PORTFOLIO
                         INTERNATIONAL EQUITY PORTFOLIO
                       INTERNATIONAL SMALL CAP PORTFOLIO
                             ASIAN EQUITY PORTFOLIO
                           EUROPEAN EQUITY PORTFOLIO
                           JAPANESE EQUITY PORTFOLIO
                            LATIN AMERICAN PORTFOLIO
 
                               PORTFOLIOS OF THE
 
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
 
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
 
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                      P.O. BOX 2798, BOSTON, MA 02208-2798
 
- ---------------------------------------
- ---------------------------------------
- ---------------------------------------
- ---------------------------------------
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
     ----------------------------------------------------------------------
 
                           EMERGING MARKETS PORTFOLIO
                        EMERGING MARKETS DEBT PORTFOLIO
 
                               PORTFOLIOS OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
 
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
                                ----------------
 
   
    Morgan  Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company, or mutual fund, which offers redeemable shares in
a   series   of   diversified   and   non-diversified   investment    portfolios
("portfolios").   The  Fund   currently  consists   of  twenty-eight  portfolios
representing a  broad range  of  investment choices.  The  Fund is  designed  to
provide clients with attractive alternatives for meeting their investment needs.
This  prospectus (the  "Prospectus") pertains  to the  Class A  and the  Class B
shares of the Emerging Markets Portfolio and the Emerging Markets Debt Portfolio
(the "Portfolios").  On  January 2,  1996,  the Portfolios  began  offering  two
classes  of shares, the  Class A shares and  the Class B  shares, except for the
Money Market,  Municipal Money  Market and  International Small  Cap  Portfolios
which  only offer Class  A shares. All  shares of the  Portfolios owned prior to
January 2, 1996 were redesignated Class A shares on January 2, 1996. The Class A
and Class B shares  currently offered by the  Portfolios have different  minimum
investment  requirements and fund expenses. Shares of the portfolios are offered
with no sales charge or  exchange or redemption fee  (with the exception of  the
International Small Cap Portfolio).
    
 
   
    The  EMERGING  MARKETS  PORTFOLIO seeks  long-term  capital  appreciation by
investing primarily in equity securities of emerging country issuers.
    
 
   
    The EMERGING MARKETS  DEBT PORTFOLIO  seeks high total  return by  investing
primarily  in debt  securities of  government, government-related  and corporate
issuers located in emerging countries.
    
 
   
    Emerging markets  securities  are subject  to  special risks.  See  "Foreign
Investment Risk Factors."
    
 
   
    INVESTORS  SHOULD NOTE THAT EACH PORTFOLIO MAY INVEST UP TO 10% OF ITS TOTAL
ASSETS IN RESTRICTED SECURITIES AND  UP TO 25% OF  ITS NET ASSETS IN  RESTRICTED
SECURITIES THAT ARE RULE 144A SECURITIES. SEE "ADDITIONAL INVESTMENT INFORMATION
- --   NON-PUBLICLY   TRADED   SECURITIES,  PRIVATE   PLACEMENTS   AND  RESTRICTED
SECURITIES."  INVESTMENTS  IN  RESTRICTED  SECURITIES  IN  EXCESS  OF  5%  OF  A
PORTFOLIO'S  TOTAL ASSETS MAY BE CONSIDERED  A SPECULATIVE ACTIVITY, MAY INVOLVE
GREATER RISK AND MAY INCREASE THE PORTFOLIO'S EXPENSES.
    
 
   
    THE EMERGING MARKETS PORTFOLIO  MAY INVEST IN  EQUITY SECURITIES OF  RUSSIAN
COMPANIES.  RUSSIA'S SYSTEM OF  SHARE REGISTRATION AND  CUSTODY INVOLVES CERTAIN
RISKS OF  LOSS  THAT ARE  NOT  NORMALLY  ASSOCIATED WITH  INVESTMENTS  IN  OTHER
SECURITIES MARKETS. SEE "ADDITIONAL INVESTMENT INFORMATION -- RUSSIAN SECURITIES
TRANSACTIONS."
    
 
   
    The  Fund is designed  to meet the investment  needs of discerning investors
who place a premium on quality  and personal service. With Morgan Stanley  Asset
Management   Inc.  as   Adviser  and   Administrator  (the   "Adviser"  and  the
"Administrator") and with Morgan Stanley  & Co. Incorporated ("Morgan  Stanley")
as Distributor, the Fund makes available to institutional investors and high net
worth  individual  investors  a  series of  portfolios  which  benefit  from the
investment expertise and commitment to excellence associated with Morgan Stanley
and its affiliates.
    
 
   
    This Prospectus is designed to set forth concisely the information about the
Fund that a prospective investor should  know before investing and it should  be
retained  for future reference. The Fund  offers additional Portfolios which are
described in other prospectuses and under the Prospectus Summary section herein.
The Fund currently offers the following portfolios: (i) GLOBAL AND INTERNATIONAL
EQUITY -- Active  Country Allocation, Asian  Equity, Emerging Markets,  European
Equity,  Global  Equity, Gold,  International  Equity, International  Small Cap,
Japanese Equity and Latin  American Portfolios; (ii)  U.S. EQUITY --  Aggressive
Equity,  Emerging Growth, Equity Growth, MicroCap,  Small Cap Value Equity, U.S.
Real Estate and Value Equity  Portfolios; (iii) BALANCED -- Balanced  Portfolio;
(iv)  FIXED INCOME -- Emerging Markets  Debt, Fixed Income, Global Fixed Income,
High Yield, Mortgage-Backed  Securities and Municipal  Bond Portfolios; and  (v)
MONEY  MARKET -- Money Market and  Municipal Money Market Portfolios. Additional
information  about  the  Fund  is  contained  in  a  "Statement  of   Additional
Information,"  dated May 1, 1996, which is incorporated herein by reference. The
Statement of Additional Information and the prospectuses pertaining to the other
portfolios of the Fund are available upon request and without charge by  writing
or calling the Fund at the address and telephone number set forth above.
    
 
   
 THESE  SECURITIES HAVE NOT BEEN APPROVED  OR DISAPPROVED BY THE SECURITIES AND
 EXCHANGE COMMISSION  OR  ANY  STATE SECURITIES  COMMISSION,  NOR  HAS  THE
     SECURITIES   AND  EXCHANGE  COMMISSION   OR  ANY  STATE  SECURITIES
        COMMISSION PASSED  UPON  THE  ACCURACY OR  ADEQUACY  OF  THIS
           PROSPECTUS.  ANY REPRESENTATION TO                  THE
                        CONTRARY IS A CRIMINAL OFFENSE.
    
 
   
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1996.
    
<PAGE>
                                 FUND EXPENSES
 
    The  following table illustrates the expenses and fees that a shareholder of
the Portfolios indicated below will incur:
   
<TABLE>
<CAPTION>
                                                                                              EMERGING
                                                                                 EMERGING      MARKETS
                                                                                  MARKETS       DEBT
SHAREHOLDER TRANSACTION EXPENSES                                                 PORTFOLIO    PORTFOLIO
- ------------------------------------------------------------------------------  -----------  -----------
<S>                                                                             <C>          <C>
Maximum Sales Load Imposed on Purchases
  Class A.....................................................................        None         None
  Class B.....................................................................        None         None
Maximum Sales Load Imposed on Reinvested Dividends
  Class A.....................................................................        None         None
  Class B.....................................................................        None         None
Deferred Sales Load
  Class A.....................................................................        None         None
  Class B.....................................................................        None         None
Redemption Fees
  Class A.....................................................................        None         None
  Class B.....................................................................        None         None
Exchange Fees
  Class A.....................................................................        None         None
  Class B.....................................................................        None         None
 
<CAPTION>
 
ANNUAL FUND OPERATING EXPENSES
- ------------------------------------------------------------------------------
 (AS A PERCENTAGE OF AVERAGE NET ASSETS)
<S>                                                                             <C>          <C>
Management Fee*
  Class A.....................................................................       1.25%        1.00%
  Class B.....................................................................       1.25%        1.00%
12b-1 Fees
  Class A.....................................................................        None         None
  Class B.....................................................................       0.25%        0.25%
Other Expenses
  Class A.....................................................................       0.47%        0.75%
  Class B.....................................................................       0.47%        0.75%
                                                                                -----------  -----------
Total Operating Expenses*
  Class A.....................................................................       1.72%        1.75%
  Class B.....................................................................       1.97%        2.00%
                                                                                -----------  -----------
                                                                                -----------  -----------
</TABLE>
    
 
- ------------------------------
   
*The Adviser has  agreed to waive  its management fees  and/or to reimburse  the
 Portfolios, if necessary, if such fees would cause the Portfolios' total annual
 operating  expenses, as  a percentage  of average  daily net  assets, to exceed
 1.75% for the Class A shares and  2.00% for the Class B shares. The  management
 fees  are 1.25% for the  Emerging Markets Portfolio and  1.00% for the Emerging
 Markets Debt Portfolio. The Adviser reserves the right to terminate any of  its
 fee  waivers and/or expense reimbursements at  any time in its sole discretion.
 For further information on Fund expenses, see "Management of the Fund."
    
 
                                       2
<PAGE>
   
    The purpose of the  table above is to  assist the investor in  understanding
the  various expenses that an  investor in the Portfolios  will bear directly or
indirectly. The Class A expenses and fees for the Portfolios are based on actual
figures for the fiscal year  ended December 31, 1995.  The Class B expenses  and
fees  for each Portfolio are based on estimates, assuming that the average daily
net assets of the Class B shares  of each Portfolio will be $50,000,000.  "Other
Expenses"  include  Board  of  Directors'  fees  and  expenses,  amortization of
organizational costs, filing fees, professional  fees and costs for  shareholder
reports.  Due to  the continuous nature  of Rule  12b-1 fees, long  term Class B
shareholders may pay  more than the  equivalent of the  maximum front-end  sales
charges  otherwise  permitted by  the  Rules of  Fair  Practice of  the National
Association of Securities Dealers, Inc. ("NASD").
    
 
    The following  example illustrates  the expenses  that you  would pay  on  a
$1,000  investment assuming (1) a 5% annual rate of return and (2) redemption at
the end of each time period. As noted in the table above, the Portfolios  charge
no  redemption  fees  of any  kind.  The  following example  is  based  on total
operating expenses of the Portfolios after fee waivers.
 
   
<TABLE>
<CAPTION>
                                                                       1 YEAR       3 YEARS      5 YEARS     10 YEARS
                                                                     -----------  -----------  -----------  -----------
<S>                                                                  <C>          <C>          <C>          <C>
Emerging Markets Portfolio
  Class A..........................................................   $      17    $      54    $      93    $     203
  Class B..........................................................          20           62          106          230
Emerging Markets Debt Portfolio
  Class A..........................................................          18           55           95          206
  Class B..........................................................          20           63          108          233
</TABLE>
    
 
    THIS EXAMPLE SHOULD  NOT BE CONSIDERED  A REPRESENTATION OF  PAST OR  FUTURE
EXPENSES  OR  PERFORMANCE. ACTUAL  EXPENSES MAY  BE GREATER  OR LESS  THAN THOSE
SHOWN.
 
    The Fund intends  to continue to  comply with all  state laws that  restrict
investment  company expenses. Currently, the most restrictive state law requires
that the aggregate annual expenses of an investment company shall not exceed two
and one-half percent (2 1/2%)  of the first $30  million of average net  assets,
two  percent (2%)  of the next  $70 million of  average net assets,  and one and
one-half percent  (1  1/2%) of  the  remaining  net assets  of  such  investment
company.
 
    The  Adviser has agreed to a reduction in  the amounts payable to it, and to
reimburse the Portfolios, if  necessary, if in  any fiscal year  the sum of  the
Portfolio's expenses exceeds the limit set by applicable state laws.
 
                                       3
<PAGE>
                              FINANCIAL HIGHLIGHTS
 
   
    The following table provides financial highlights for the Class A shares for
the  Emerging  Markets and  Emerging  Markets Debt  Portfolios  for each  of the
periods presented. The audited financial highlights  for the Class A shares  for
the  fiscal  year ended  December  31, 1995  are  part of  the  Fund's financial
statements which  appear  in the  Fund's  December  31, 1995  Annual  Report  to
Shareholders  and  which  are included  in  the Fund's  Statement  of Additional
Information. The  Portfolios'  financial  highlights for  each  of  the  periods
presented  have been audited  by Price Waterhouse  LLP, whose unqualified report
thereon is also included in the Statement of Additional Information.  Additional
performance  information for the Class A shares of the Portfolios is included in
the Annual Report. The Annual Report and the financial statements therein, along
with the Statement of Additional Information, are available at no cost from  the
Fund  at  the address  and  telephone number  noted on  the  cover page  of this
Prospectus. Financial highlights are  not available for the  new Class B  shares
since  they were not offered as of  December 31, 1995. Subsequent to October 31,
1992 (the Fund's prior fiscal year end), the Fund changed its fiscal year end to
December 31. The following  information should be read  in conjunction with  the
financial statements and notes thereto.
    
 
                                       4
<PAGE>
                           EMERGING MARKETS PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                      TWO
                                                       SEPTEMBER    MONTHS       YEAR        YEAR
                                                          25,        ENDED       ENDED       ENDED       YEAR
                                                       1992* TO    DECEMBER    DECEMBER    DECEMBER      ENDED
                                                        OCTOBER       31,         31,         31,      DECEMBER
                                                       31, 1992      1992        1993        1994      31, 1995
                                                       ---------   ---------   ---------   ---------   ---------
<S>                                                    <C>         <C>         <C>         <C>         <C>
NET ASSET VALUE, BEGINNING OF PERIOD.................  $ 10.00     $ 10.11     $ 10.22     $ 19.00     $ 16.30
                                                       ---------   ---------   ---------   ---------   ---------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income/(Loss) (1)...................       --          --       (0.01)      (0.04)       0.08
  Net Realized and Unrealized Gain/ (Loss) on
   Investments.......................................     0.11        0.11        8.79       (1.69)      (2.05)
                                                       ---------   ---------   ---------   ---------   ---------
  Total from Investment Operations...................     0.11        0.11        8.78       (1.73)      (1.97)
                                                       ---------   ---------   ---------   ---------   ---------
DISTRIBUTIONS
  Net Investment Income..............................       --          --          --          --       (0.06)
  Net Realized Gain..................................       --          --          --       (0.97)      (1.13)
                                                       ---------   ---------   ---------   ---------   ---------
  Total Distributions................................       --          --          --       (0.97)      (1.19)
                                                       ---------   ---------   ---------   ---------   ---------
NET ASSET VALUE, END OF PERIOD.......................  $ 10.11     $ 10.22     $ 19.00     $ 16.30     $ 13.14
                                                       ---------   ---------   ---------   ---------   ---------
TOTAL RETURN.........................................     1.10%       1.09%      85.91%      (9.63)%    (12.77)%
                                                       ---------   ---------   ---------   ---------   ---------
                                                       ---------   ---------   ---------   ---------   ---------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)................  $28,806     $74,219     $735,352    $929,638    $876,591
Ratio of Expenses to Average Net
 Assets (1)(2).......................................     1.75%**     1.75%**     1.75%       1.75%       1.72%
Ratio of Net Investment Gain/(Loss) to Average Net
 Assets (1)(2).......................................    (0.53)%**   (0.33)%**   (0.06)%     (0.26)%      0.60%
Portfolio Turnover Rate..............................        0%          2%         52%         32%         54%
- ------------------------
</TABLE>
    
 
   
<TABLE>
<S> <C>                                                 <C>         <C>         <C>         <C>         <C>
(1) Effect of voluntary expense limitation during the period:
    Per share benefit to net investment income........  $  0.02     $  0.00     $  0.01         N/A         N/A
    Ratios before expense limitation:
    Expenses to Average Net Assets....................     4.82%**     2.48%**     1.79%        N/A         N/A
    Net Investment Gain/(Loss) to Average
       Net Assets.....................................    (3.60)%**   (1.06)%**   (0.10)%       N/A         N/A
</TABLE>
    
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to  receive a management  fee calculated at  an annual rate  of 1.25% of the
    average daily net assets of the Emerging Markets Portfolio. The Adviser  has
    agreed  to waive  a portion  of this  fee and/or  reimburse expenses  of the
    Portfolio to the extent that the  total operating expenses of the  Portfolio
    exceed 1.75% of the average daily net assets of the Class A shares and 2.00%
    of  the average net assets of the Class  B shares. The Adviser did not waive
    fees or reimburse expenses for the  years ended December 31, 1994 and  1995.
    In  the period ended October  31, 1992, the two  month period ended December
    31, 1992 and the year ended  December 31, 1993, the Adviser waived  advisory
    fees  and/or reimbursed  expenses totalling  $58,000, $50,000  and $122,000,
    respectively, for the Emerging Markets Portfolio.
    
 
   
 * Commencement of Operations.
    
 
   
** Annualized.
    
 
                                       5
<PAGE>
                        EMERGING MARKETS DEBT PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                                     PERIOD FROM
                                                                                  FEBRUARY 1, 1994*   YEAR ENDED
                                                                                   TO DECEMBER 31,   DECEMBER 31,
                                                                                        1994             1995
                                                                                  -----------------  -------------
<S>                                                                               <C>                <C>
NET ASSET VALUE, BEGINNING OF PERIOD............................................     $     10.00      $      8.59
                                                                                        --------     -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income.........................................................            0.50             1.36
  Net Realized and Unrealized Gain/(Loss) on Investments........................           (1.91)            0.91
                                                                                        --------     -------------
  Total from Investment Operations..............................................           (1.41)            2.27
                                                                                        --------     -------------
DISTRIBUTIONS
  Net Investment Income.........................................................              --            (1.86)
  Net Realized Gain.............................................................                            (0.41)
                                                                                        --------     -------------
    Total Distributions.........................................................              --            (2.27)
                                                                                        --------     -------------
NET ASSET VALUE, END OF PERIOD..................................................     $      8.59      $      8.59
                                                                                        --------     -------------
                                                                                        --------     -------------
TOTAL RETURN....................................................................          (14.10)%          28.23%
                                                                                        --------     -------------
                                                                                        --------     -------------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)...........................................     $   144,949      $   181,878
Ratio of Expenses to Average Net Assets.........................................            1.49%**          1.75%
Ratio of Net Investment Income to Average Net Assets............................            9.97%**         14.70%
Portfolio Turnover Rate.........................................................             273%             406%
- ------------------------
</TABLE>
    
 
 * Commencement of Operations.
** Annualized.
 
                                       6
<PAGE>
                               PROSPECTUS SUMMARY
 
   
THE FUND
    
 
   
    The  Fund  consists  of  twenty-eight  portfolios,  offering   institutional
investors  and high net  worth individual investors a  broad range of investment
choices coupled with the advantages of a no-load mutual fund with Morgan Stanley
and its affiliates providing customized  services as Adviser, Administrator  and
Distributor.   Each  portfolio  offers  Class  A  shares  and,  except  for  the
International Small Cap,  Money Market  and Municipal  Money Market  Portfolios,
also  offers Class B shares. Each portfolio has its own investment objective and
policies designed to meet its specific  goals. The investment objective of  each
Portfolio described in this Prospectus is as follows:
    
 
   
    -The  EMERGING  MARKETS PORTFOLIO  seeks  long-term capital  appreciation by
     investing primarily in equity securities of emerging country issuers.
    
 
   
    -The EMERGING MARKETS DEBT  PORTFOLIO seeks high  total return by  investing
     primarily   in  debt  securities   of  government,  government-related  and
     corporate issuers located  in emerging countries.  The other portfolios  of
     the Fund are described in other prospectuses which may be obtained from the
     Fund  at the address and  telephone number noted on  the cover page of this
     Prospectus. The objectives of these other portfolios are listed below:
    
 
   
    GLOBAL AND INTERNATIONAL EQUITY:
    
 
   
    -The  ACTIVE   COUNTRY   ALLOCATION  PORTFOLIO   seeks   long-term   capital
     appreciation  by investing in accordance with country weightings determined
     by the  Adviser in  equity securities  of non-U.S.  issuers which,  in  the
     aggregate, replicate broad country indices.
    
 
   
    -The   ASIAN  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing primarily in equity securities of Asian issuers.
    
 
   
    -The CHINA GROWTH PORTFOLIO seeks to provide long-term capital  appreciation
     by  investing primarily in the equity securities of issuers in The People's
     Republic of China, Hong Kong and Taiwan.
    
 
   
    -The EUROPEAN  EQUITY  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing primarily in equity securities of European issuers.
    
 
   
    -The  GLOBAL  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing primarily in equity securities  of issuers throughout the  world,
     including U.S. issuers.
    
 
   
    -The  GOLD  PORTFOLIO  seeks  long-term  capital  appreciation  by investing
     primarily in equity securities of  foreign and domestic issuers engaged  in
     gold-related activities.
    
 
   
    -The  INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation by
     investing primarily in equity securities of non-U.S. issuers.
    
 
   
    -The INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation  by
     investing  primarily in equity securities of non-U.S. issuers in accordance
     with EAFE  country  (as defined  in  "Investment Objectives  and  Policies"
     below) weightings determined by the Adviser.
    
 
   
    -The  INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital appreciation
     by investing primarily in equity securities of non-U.S. issuers with equity
     market capitalizations of under $1 billion.
    
 
                                       7
<PAGE>
    -The JAPANESE  EQUITY  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing primarily in equity securities of Japanese issuers.
 
    -The  LATIN  AMERICAN  PORTFOLIO  seeks  long-term  capital  appreciation by
     investing primarily in equity securities of Latin American issuers and debt
     securities  issued  or   guaranteed  by  Latin   American  governments   or
     governmental entities.
 
    U.S. EQUITY:
 
   
    -The  AGGRESSIVE EQUITY  PORTFOLIO seeks  capital appreciation  by investing
     primarily in corporate equity and equity-linked securities.
    
 
   
    -The EMERGING  GROWTH  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing  primarily  in  growth-oriented equity  securities  of  small- to
     medium-sized corporations.
    
 
   
    -The  EQUITY  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing   in  growth-oriented  equity  securities  of  medium  and  large
     capitalization companies.
    
 
   
    -The MICROCAP PORTFOLIO  seeks long-term capital  appreciation by  investing
     primarily in growth-oriented equity securities of small corporations.
    
 
   
    -The  SMALL  CAP  VALUE EQUITY  PORTFOLIO  seeks long-term  total  return by
     investing in  undervalued  equity  securities  of  small-  to  medium-sized
     companies.
    
 
   
    -The  U.S.  REAL ESTATE  PORTFOLIO seeks  to  provide above  average current
     income and long-term capital appreciation by investing primarily in  equity
     securities  of companies in  the U.S. real  estate industry, including real
     estate investment trusts.
    
 
   
    -The VALUE EQUITY PORTFOLIO seeks high  total return by investing in  equity
     securities  which the  Adviser believes to  be undervalued  relative to the
     stock market in general at the time of purchase.
    
 
   
    BALANCED:
    
 
   
    -The BALANCED PORTFOLIO seeks high total return while preserving capital  by
     investing  in  a combination  of  undervalued equity  securities  and fixed
     income securities.
    
 
   
    FIXED INCOME:
    
 
   
    -The FIXED INCOME PORTFOLIO seeks to produce a high total return  consistent
     with the preservation of capital by investing in a diversified portfolio of
     fixed income securities.
    
 
   
    -The  GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real rate
     of return while preserving capital by investing in fixed income  securities
     of issuers throughout the world, including U.S. issuers.
    
 
   
    -The  HIGH YIELD PORTFOLIO seeks to maximize  total return by investing in a
     diversified portfolio of high  yield fixed income  securities that offer  a
     yield  above  that  generally available  on  debt securities  in  the three
     highest rating categories of the recognized rating services.
    
 
   
    -The MORTGAGE-BACKED SECURITIES PORTFOLIO seeks  to produce as high a  level
     of  current income  as is  consistent with  the preservation  of capital by
     investing  primarily  in  a  variety  of  investment-grade  mortgage-backed
     securities.
    
 
                                       8
<PAGE>
   
    -The  MUNICIPAL  BOND PORTFOLIO  seeks to  produce a  high level  of current
     income  consistent  with  preservation  of  principal  through   investment
     primarily  in municipal obligations,  the interest on  which is exempt from
     federal income tax.
    
 
   
    MONEY MARKET:
    
 
   
    -The MONEY MARKET PORTFOLIO  seeks to maximize  current income and  preserve
     capital  while maintaining  high levels  of liquidity  through investing in
     high quality money market instruments with remaining maturities of one year
     or less.
    
 
   
    -The MUNICIPAL MONEY MARKET PORTFOLIO  seeks to maximize current  tax-exempt
     income  and  preserve capital  while maintaining  high levels  of liquidity
     through investing in high quality  money market instruments with  remaining
     maturities of one year or less which are exempt from federal income tax.
    
 
INVESTMENT MANAGEMENT
 
   
    Morgan  Stanley Asset Management  Inc., a wholly  owned subsidiary of Morgan
Stanley Group  Inc.,  which,  together  with  its  affiliated  asset  management
companies,  at December 31, 1995 had approximately $57.4 billion in assets under
management as  an  investment  manager  or  as  a  fiduciary  adviser,  acts  as
investment  adviser to the Fund  and each of its  portfolios. See "Management of
the Fund -- Investment Adviser" and "Management of the Fund -- Administrator."
    
 
HOW TO INVEST
 
   
    Class A shares of  each Portfolio are offered  directly to investors at  net
asset  value with no sales  commission or 12b-1 charges.  Class B shares of each
Portfolio are offered at net  asset value with no  sales commission, but with  a
12b-1  fee, which  is accrued daily  and paid  quarterly, equal to  0.25% of the
Class B shares' average daily net assets on an annualized basis. Share purchases
may be  made  by  sending  investments  directly to  the  Fund  or  through  the
Distributor.  Shares  in a  Portfolio account  opened prior  to January  2, 1996
(each, a "Pre-1996 Account") were designated Class A shares on January 2,  1996.
For  a Portfolio account opened  on or after January  2, 1996 (a "New Account"),
the minimum initial investment is $500,000  for Class A shares and $100,000  for
Class B shares. Certain exceptions to the foregoing minimums apply to (1) shares
in  a Pre-1996  Account with a  value of  $100,000 or more  on March  1, 1996 (a
"Grandfathered Class A Account"); (2) Portfolio accounts held by officers of the
Adviser and  its  affiliates;  and  (3) certain  advisory  or  asset  allocation
accounts,  such as Total Funds Management accounts, managed by Morgan Stanley or
its affiliates, including the Adviser ("Managed Accounts"). The Adviser reserves
the right in its sole  discretion to determine which  of such advisory or  asset
allocation accounts shall be Managed Accounts. For information regarding Managed
Accounts  please contact your Morgan Stanley  account representative or the Fund
at the telephone number provided  on the cover of  this Prospectus. Shares in  a
Pre-1996  Account  with  a value  of  less than  $100,000  on March  1,  1996 (a
"Grandfathered Class B Account") converted to  Class B shares on March 1,  1996.
The minimum investment levels may be waived at the discretion of the Adviser for
(i)  certain employees  and customers  of Morgan  Stanley or  its affiliates and
certain  trust  departments,  brokers,   dealers,  agents,  financial   planers,
financial  services  firms  or investment  advisers  that have  entered  into an
agreement with  Morgan  Stanley  or  its affiliates;  and  (ii)  retirement  and
deferred  compensation plans and trusts, used to fund such plans, including, but
not limited to, those defined in Section  401(a), 403(b) or 457 of the  Internal
Revenue Code of 1986, as amended, and "rabbi trusts". See "Purchase of Shares --
Minimum  Investment  and  Account Sizes;  Conversion  from  Class A  to  Class B
Shares."
    
 
                                       9
<PAGE>
   
    The minimum  subsequent  investment for  each  Portfolio account  is  $1,000
(except  for automatic reinvestment of dividends and capital gains distributions
for which there is no minimum).  Such subsequent investments will be applied  to
purchase  additional  shares  in the  same  class  held by  a  shareholder  in a
Portfolio account. See "Purchase of Shares -- Additional Investments."
    
 
HOW TO REDEEM
 
   
    Class A shares or Class  B shares of each Portfolio  may be redeemed at  any
time, without cost, at the net asset value per share of shares of the applicable
class  next determined after  receipt of the  redemption request. The redemption
price may be more or less than the purchase price. Certain redemptions may cause
involuntary redemption or  conversion. Class  A or Class  B shares  held in  New
Accounts  are subject to involuntary  redemption if shareholder redemption(s) of
such shares  reduces the  value of  such account  to less  than $100,000  for  a
continuous  60-day  period. Involuntary  redemption  does not  apply  to Managed
Accounts, Grandfathered Class  A Accounts  and Grandfathered  Class B  Accounts,
regardless  of the value of such accounts. Class  A shares in a New Account will
convert to Class B  shares if shareholder redemption(s)  of such shares  reduces
the  value of such account to less than $500,000 for a continuous 60-day period.
Class B shares in a  New Account will convert to  Class A shares if  shareholder
purchases of additional Class B shares or market activity cause the value of the
Class B shares in the New Account to increase to $500,000 or more. See "Purchase
of  Shares --  Minimum Account Sizes  and Involuntary Redemption  of Shares" and
"Redemption of Shares."
    
 
RISK FACTORS
 
    Investing in emerging country securities involves certain considerations not
typically associated with investing in  securities of U.S. companies,  including
(1)  restrictions on foreign investment and  on repatriation of capital invested
in emerging countries,  (2) currency  fluctuations, (3) the  cost of  converting
foreign  currency into U.S.  dollars, (4) potential  price volatility and lesser
liquidity of shares traded on emerging  country securities markets or lack of  a
secondary  trading market  for such  securities and  (5) political  and economic
risks, including the risk of nationalization or expropriation of assets and  the
risk  of war. In  addition, accounting, auditing,  financial and other reporting
standards in  emerging  countries  are  not equivalent  to  U.S.  standards  and
therefore,  disclosure of certain material information  may not be made and less
information may be available to  investors investing in emerging countries  than
in  the  U.S.  There  is  also generally  less  governmental  regulation  of the
securities industry in emerging countries  than in the United States.  Moreover,
it  may be more difficult to  obtain a judgment in a  court outside the U.S. See
"Investment Objectives and Policies" and "Additional Investment Information." In
addition, each Portfolio may invest in repurchase agreements, lend its portfolio
securities and purchase securities  on a when-issued  basis. Each Portfolio  may
invest  in foreign currency futures contracts and options to hedge currency risk
associated with investment  in non-U.S. dollar  denominated securities. Each  of
these  investment strategies involves  specific risks which  are described under
"Investment Objectives  and Policies"  and "Additional  Investment  Information"
herein  and  under  "Investment Objectives  and  Policies" in  the  Statement of
Additional Information.
 
   
    The Emerging Markets Portfolio  may invest in  equity securities of  Russian
companies.  The registration, clearing and settlement of securities transactions
in Russia  are  subject  to  significant  risks  not  normally  associated  with
securities  transactions in the United States  and other more developed markets.
See "Additional Investment Information -- Russian Securities Transactions."
    
 
                                       10
<PAGE>
                       INVESTMENT OBJECTIVES AND POLICIES
 
    The investment objective of each Portfolio is described below, together with
the policies the Fund employs in its efforts to achieve these objectives.  There
is  no assurance that each Portfolio will attain its objective. Each Portfolio's
investment objective is a  fundamental policy which may  not be changed  without
the approval of a majority of the Portfolio's outstanding voting securities. The
investment  policies described  below are  not fundamental  policies and  may be
changed without shareholder approval.
 
THE EMERGING MARKETS PORTFOLIO
 
    The investment objective of  the Portfolio is  to provide long-term  capital
appreciation  by investing  primarily in  equity securities  of emerging country
issuers. With respect  to the  Portfolio, equity securities  include common  and
preferred stocks, convertible securities, rights and warrants to purchase common
stocks.  Under normal conditions,  at least 65% of  the Portfolio's total assets
will be  invested  in  emerging  country equity  securities.  As  used  in  this
Prospectus,  the term  "emerging country" applies  to any country  which, in the
opinion of the Adviser, is generally considered to be an emerging or  developing
country   by  the   international  financial   community,  which   includes  the
International Bank for  Reconstruction and Development  (more commonly known  as
the  World Bank) and the International  Finance Corporation. There are currently
over 130  countries  which,  in  the  opinion  of  the  Adviser,  are  generally
considered to be emerging or developing countries by the international financial
community,  approximately  40  of  which  currently  have  stock  markets. These
countries generally include every nation in the world except the United  States,
Canada,  Japan,  Australia,  New Zealand  and  most nations  located  in Western
Europe. Currently, investing in many emerging  countries is not feasible or  may
involve  unacceptable political risks. The  Portfolio will focus its investments
on those  emerging market  countries  in which  it  believes the  economies  are
developing  strongly and in  which the markets  are becoming more sophisticated.
The Portfolio  intends to  invest primarily  in  some or  all of  the  following
countries:
 
<TABLE>
<S>                     <C>                     <C>                     <C>
Argentina               Botswana                Brazil                  Chile
China                   Colombia                Greece                  Hong Kong
Hungary                 India                   Indonesia               Jamaica
Jordan                  Kenya                   Malaysia                Mexico
Nigeria                 Pakistan                Peru                    Philippines
Poland                  Portugal                Russia                  South Africa
South Korea             Sri Lanka               Taiwan                  Thailand
Turkey                  Venezuela               Zimbabwe
</TABLE>
 
As  markets  in other  countries develop,  the Portfolio  expects to  expand and
further diversify the emerging countries in which it invests. The Portfolio does
not intend to  invest in any  security in a  country where the  currency is  not
freely  convertible  to  U.S. dollars,  unless  the Portfolio  has  obtained the
necessary governmental licensing to convert such currency or other appropriately
licensed or sanctioned contractual guarantees to protect such investment against
loss of  that currency's  external  value, or  the  Portfolio has  a  reasonable
expectation  at the time the investment is made that such governmental licensing
or other appropriately licensed  or sanctioned guarantees  would be obtained  or
that the currency in which the security is quoted would be freely convertible at
the time of any proposed sale of the security by the Portfolio.
 
    An emerging country security is one issued by a company that, in the opinion
of  the  Adviser, has  one or  more  of the  following characteristics:  (i) its
principal   securities   trading   market    is   in   an   emerging    country,
 
                                       11
<PAGE>
(ii)  alone, or on a consolidated basis, the  company derives 50% or more of its
annual revenue from either goods produced,  sales made or services performed  in
emerging countries; or (iii) the company is organized under the laws of, and has
a principal office in, an emerging country. The Adviser will base determinations
as  to eligibility on  publicly available information and  inquiries made to the
companies. (See "Foreign Investment Risk Factors" for a discussion of the nature
of information publicly available for non-U.S. companies.)
 
   
    To the  extent that  the Portfolio's  assets are  not invested  in  emerging
country  equity securities, the remainder  of the assets may  be invested in (i)
debt securities denominated in the currency of an emerging country or issued  or
guaranteed  by  an emerging  country company  or the  government of  an emerging
country, (ii) equity  or debt  securities of corporate  or governmental  issuers
located  in industrialized countries, and  (iii) short-term and medium-term debt
securities of  the  type  described below  under  "Temporary  Instruments."  The
Portfolio's  assets  may  be  invested in  debt  securities  when  the Portfolio
believes that, based  upon factors  such as  relative interest  rate levels  and
foreign  exchange rates, such debt  securities offer opportunities for long-term
capital appreciation. It is likely that many of the debt securities in which the
Portfolio will invest will be unrated, and whether or not rated, such securities
may have speculative  characteristics. When deemed  appropriate by the  Adviser,
the  Portfolio may invest up to 10% of its total assets (measured at the time of
the investment) in lower quality debt securities. Lower quality debt securities,
also known as "junk bonds," are  often considered to be speculative and  involve
greater  risk  of  default or  price  changes  due to  changes  in  the issuer's
creditworthiness. As  of  the date  of  this prospectus,  less  than 5%  of  the
Portfolio's total assets were invested in junk bonds. The market prices of these
securities  may fluctuate more  than those of higher  quality securities and may
decline significantly  in  periods of  general  economic difficulty,  which  may
follow  periods  of  rising interest  rates.  Securities in  the  lowest quality
category may present the risk  of default, or may  be in default. For  temporary
defensive  purposes, the Portfolio may invest less  than 65% of its total assets
in emerging country equity securities, in which case the Portfolio may invest in
other equity securities or may invest  in debt securities of the kind  described
under "Temporary Investments" below.
    
 
   
    The  Portfolio  may  invest  indirectly in  securities  of  emerging country
issuers through sponsored or unsponsored American Depositary Receipts  ("ADRs").
ADRs  may not necessarily be denominated in  the same currency as the underlying
securities into which  they may be  converted. In addition,  the issuers of  the
stock  of unsponsored ADRs are not obligated to disclose material information in
the U.S. and, therefore, there may not be a correlation between such information
and the market value of the ADR.
    
 
THE EMERGING MARKETS DEBT PORTFOLIO
 
    The investment objective of the Portfolio  is to seek high total return.  In
seeking  to achieve this objective,  the Portfolio will seek  to invest at least
65% of its total assets in debt securities of government and  government-related
issuers located in emerging countries (including participations in loans between
governments   and  financial   institutions),  and  of   entities  organized  to
restructure outstanding debt  of such  issuers. In addition,  the Portfolio  may
invest  up to 35%  of its total  assets in debt  securities of corporate issuers
located in or organized under the laws of emerging countries. See "The  Emerging
Markets Portfolio" above for a definition of emerging countries.
 
    The  Adviser intends  to invest the  Portfolio's assets  in emerging country
debt securities that provide a high level  of current income, while at the  same
time   holding  the  potential   for  capital  appreciation   if  the  perceived
 
                                       12
<PAGE>
creditworthiness of the  issuer improves due  to improving economic,  financial,
political,  social or  other conditions  in the country  in which  the issuer is
located. Currently,  investing  in  many  emerging  country  securities  is  not
feasible  or may involve unacceptable  political risks. Initially, the Portfolio
expects that its investments  in emerging country debt  securities will be  made
primarily in some or all of the following emerging countries:
 
<TABLE>
<S>                     <C>                     <C>
Algeria                 India                   Philippines
Argentina               Indonesia               Poland
Brazil                  Ivory Coast             Portugal
Bulgaria                Jamaica                 Russia
Chile                   Jordan                  Slovakia
China                   Malaysia                South Africa
Colombia                Mexico                  Thailand
Costa Rica              Morocco                 Trinidad & Tobago
Czech Republic          Nicaragua               Tunisia
Dominican Republic      Nigeria                 Turkey
Ecuador                 Pakistan                Uruguay
Egypt                   Panama                  Venezuela
Greece                  Paraguay                Zaire
Hungary                 Peru
</TABLE>
 
In  selecting emerging country debt securities  for investment by the Investment
Fund, the Adviser will apply a market risk analysis contemplating assessment  of
factors   such  as  liquidity,  volatility,   tax  implications,  interest  rate
sensitivity, counterparty risks and technical market considerations.  Currently,
investing  in many  emerging country securities  is not feasible  or may involve
unacceptable political risks. As opportunities  to invest in debt securities  in
other  countries develop, the Portfolio expects  to expand and further diversify
the emerging countries in which it invests. While the Portfolio generally is not
restricted in  the portion  of its  assets which  may be  invested in  a  single
country  or  region,  it  is  anticipated  that,  under  normal  conditions, the
Portfolio's assets will be invested in issuers in at least three countries.
 
    The  Portfolio's   investments   in   government,   government-related   and
restructured  debt securities will consist of (i) debt securities or obligations
issued or guaranteed by governments, governmental agencies or  instrumentalities
and   political   subdivisions   located   in   emerging   countries  (including
participations in loans  between governments and  financial institutions),  (ii)
debt  securities  or  obligations  issued  by  government  owned,  controlled or
sponsored entities located in emerging countries, and (iii) interests in issuers
organized  and  operated  for  the  purpose  of  restructuring  the   investment
characteristics  of instruments issued  by any of  the entities described above.
Such type of restructuring involves the deposit with or purchase by an entity of
specific instruments and the issuance by that  entity of one or more classes  of
securities  backed by, or representing interests in, the underlying instruments.
Certain issuers of such  structured securities may be  deemed to be  "investment
companies" as defined in the Investment Company Act of 1940 (the "1940 Act"). As
a  result,  the Portfolio's  investment  in such  securities  may be  limited by
certain investment  restrictions  contained in  the  1940 Act.  See  "Additional
Investment Information -- Structured Securities."
 
    The  Portfolio's  investments in  debt  securities of  corporate  issuers in
emerging countries  may include  debt securities  or obligations  issued (i)  by
banks  located in  emerging countries or  by branches of  emerging country banks
located outside the country or (ii) by companies organized under the laws of  an
emerging country.
 
                                       13
<PAGE>
Determinations  as to eligibility will be made  by the Adviser based on publicly
available information and inquiries made to the issuer. (See "Foreign Investment
Risk Factors" for a discussion of  the nature of information publicly  available
for non-U.S. issuers.) The Portfolio may also invest in certain debt obligations
customarily referred to as "Brady Bonds," which are created through the exchange
of  existing commercial  bank loans to  foreign entities for  new obligations in
connection with  debt restructurings  under  a plan  introduced by  former  U.S.
Secretary  of the  Treasury Nicholas  F. Brady.  See "Investment  Objectives and
Policies -- Emerging  Country Equity and  Debt Securities" in  the Statement  of
Additional Information for further information about Brady Bonds.
 
    Emerging country debt securities held by the Portfolio will take the form of
bonds,  notes, bills,  debentures, convertible  securities, warrants,  bank debt
obligations, short-term paper, mortgage and other asset-backed securities,  loan
participations,  loan assignments and interests issued by entities organized and
operated for  the purpose  of restructuring  the investment  characteristics  of
instruments issued by emerging country issuers. U.S. dollar-denominated emerging
country  debt securities held by the Portfolio  will generally be listed but not
traded on a securities exchange, and non-U.S. dollar-denominated securities held
by the Portfolio may or  may not be listed or  traded on a securities  exchange.
Investments in emerging country debt securities entail special investment risks.
See  "Additional Investment Information -- Foreign Investment Risk Factors." The
Portfolio will be subject to no  restrictions on the maturities of the  emerging
country  debt securities it holds; those  maturities may range from overnight to
30 years.
 
    The Portfolio is not restricted  in the portion of  its assets which may  be
invested  in securities denominated  in a particular  currency and a substantial
portion of the Portfolio's assets may be invested in non-U.S. dollar-denominated
securities. The  portion  of  the  Portfolio's  assets  invested  in  securities
denominated  in currencies  other than  the U.S.  dollar will  vary depending on
market conditions.  Although the  Portfolio is  permitted to  engage in  a  wide
variety of investment practices designed to hedge against currency exchange rate
risks   with  respect  to  its  holdings  of  non-U.S.  dollar-denominated  debt
securities, the Portfolio may be limited  in its ability to hedge against  these
risks.  See  "Additional  Investment  Information  --  Forward  Foreign Currency
Exchange Contracts" and "Foreign Currency Futures Contracts and Options" in  the
Statement of Additional Information.
 
    In  selecting particular emerging country  debt securities for investment by
the Portfolio,  the Adviser  will  apply a  market risk  analysis  contemplating
assessment  of factors such as liquidity, volatility, tax implications, interest
rate  sensitivity,  counterparty  risks  and  technical  market  considerations.
Emerging  country  debt securities  in which  the Portfolio  may invest  will be
subject to high risk and will not be required to meet a minimum rating  standard
and  may not  be rated  for creditworthiness  by any  internationally recognized
credit rating organization. The Portfolio's investments are expected to be rated
in the lower and lowest  rating categories of internationally recognized  credit
rating  organizations or  are expected  to be  unrated securities  of comparable
quality. These  types of  debt obligations  are predominantly  speculative  with
respect  to the capacity to pay interest  and repay principal in accordance with
their terms and generally involve a greater risk of default and of volatility in
price than securities in  higher rating categories. Ratings  of a non-U.S.  debt
instrument,  to the  extent that  those ratings  are undertaken,  are related to
evaluations of the  country in which  the issuer of  the instrument is  located.
Ratings  generally  take into  account  the currency  in  which a  non-U.S. debt
instrument is denominated. Instruments issued  by a foreign government in  other
than  the local currency, for example, typically  have a lower rating than local
currency instruments  due  to the  existence  of  an additional  risk  that  the
government will be unable to obtain the required foreign currency to service its
foreign currency-denominated debt. In general, the
 
                                       14
<PAGE>
ratings of debt securities or obligations issued by a non-U.S. public or private
entity  will  not be  higher  than the  rating of  the  currency or  the foreign
currency debt of the central  government of the country  in which the issuer  is
located, regardless of the intrinsic creditworthiness of the issuer.
 
    The  Portfolio is  authorized to borrow  up to  33 1/3% of  its total assets
(including the amount  borrowed), less  all liabilities  and indebtedness  other
than  the borrowing,  for investment  purposes to  increase the  opportunity for
greater return and for  payment of dividends.  Such borrowings would  constitute
leverage,  which  is  a  speculative  characteristic.  Leveraging  will  magnify
declines as well as increases in the  net asset value of the Portfolio's  shares
and  increases  in the  yield on  the  Portfolio's investments.  See "Additional
Investment Information -- Borrowing and Other Forms of Leverage."
 
    The Portfolio  may  also invest  in  zero coupon,  pay-in-kind  or  deferred
payment  securities and in securities that  may be collateralized by zero coupon
securities (such as Brady Bonds). Zero coupon securities are securities that are
sold at a  discount to par  value and on  which interest payments  are not  made
during  the  life of  the security.  Upon  maturity, the  holder is  entitled to
receive the par value of the security.  While interest payments are not made  on
such securities, holders of such securities are deemed to have received annually
"phantom  income." Because the Portfolio will distribute its "phantom income" to
shareholders, to the extent that shareholders elect to receive dividends in cash
rather than reinvesting such dividends in additional shares, the Portfolio  will
have  fewer  assets  with which  to  purchase income  producing  securities. The
Portfolio accrues income with respect to  these securities prior to the  receipt
of  cash  payments. Pay-in-kind  securities  are securities  that  have interest
payable by  delivery of  additional  securities. Upon  maturity, the  holder  is
entitled  to receive the aggregate par value of the securities. Deferred payment
securities  are  securities   that  remain  zero   coupon  securities  until   a
predetermined  date, at which time the  stated coupon rate becomes effective and
interest becomes  payable at  regular intervals.  Zero coupon,  pay-in-kind  and
deferred  payment securities may be subject  to greater fluctuation in value and
lesser liquidity in the event of adverse market conditions than comparably rated
securities paying cash interest at regular interest payment periods.
 
    The  Portfolio  may  also   invest  up  to  5%   of  its  total  assets   in
mortgage-backed  securities  and  in  other  asset-backed  securities  issued by
non-governmental entities,  such  as  banks and  other  financial  institutions.
Mortgage-backed   securities  include   mortgage  pass-through   securities  and
collateralized mortgage obligations. Asset-backed securities are  collateralized
by  such assets  as automobile  or credit  card receivables  and are securitized
either in a pass-through  structure or in a  pay-through structure similar to  a
CMO.
 
    The   Portfolio's   investments   in   government,   government-related  and
restructured debt  instruments  are  subject to  special  risks,  including  the
inability  or  unwillingness  to  repay  principal  and  interest,  requests  to
reschedule or restructure  outstanding debt  and requests  to extend  additional
loan amounts. The Portfolio may have limited recourse in the event of default on
such  debt instruments. The Portfolio may  invest in loans, assignments of loans
and participations in loans. See "Additional Investment Information."
 
                       ADDITIONAL INVESTMENT INFORMATION
 
    AMERICAN DEPOSITARY  RECEIPTS.   The Portfolios  may on  occasion invest  in
American  Depositary Receipts ("ADRs"). ADRs are securities, typically issued by
a U.S. financial institution (a "depositary"), that evidence ownership interests
in a  security  or  a  pool  of securities  issued  by  a  foreign  issuer  (the
"underlying  issuer") and deposited  with the depositary.  ADRs include American
Depositary Shares and New York Shares and may be
 
                                       15
<PAGE>
"sponsored" or  "unsponsored."  Sponsored  ADRs are  established  jointly  by  a
depositary   and  the  underlying  issuer,   whereas  unsponsored  ADRs  may  be
established by  a depositary  without participation  by the  underlying  issuer.
Holders  of  an unsponsored  ADR generally  bear all  the costs  associated with
establishing the unsponsored ADR. The depositary of an unsponsored ADR is  under
no  obligation  to  distribute  shareholder  communications  received  from  the
underlying issuer  or to  pass through  to the  holders of  the unsponsored  ADR
voting  rights with respect  to the deposited securities  or pool of securities.
The Portfolios may invest in sponsored and unsponsored ADRs.
 
    BORROWING AND OTHER FORMS OF LEVERAGE.  The Emerging Markets Debt  Portfolio
is  authorized to borrow money from banks  and other entities in an amount equal
to up to 33 1/3% of the Portfolio's total assets (including the amount borrowed)
less all liabilities and indebtedness other than the borrowing, and may use  the
proceeds  of  the  borrowing  for  investment  purposes  or  to  pay  dividends.
Borrowings create leverage, which is a speculative characteristic. Although  the
Portfolio  is authorized to borrow, it will do so only when the Adviser believes
that  borrowing  will   benefit  the   Portfolio  after   taking  into   account
considerations  such as  the costs  of the  borrowing and  the likely investment
returns on  the securities  purchased  with borrowed  monies. Borrowing  by  the
Portfolio  will create the opportunity for increased net income but, at the same
time, will  involve  special  risk  considerations.  Leveraging  resulting  from
borrowing  will magnify  declines as  well as  increases in  the Portfolio's net
asset value per  share and  net yield.  The Portfolio  expects that  all of  its
borrowing will be made on a secured basis. The Portfolio's Custodian will either
segregate  the assets securing the  borrowing for the benefit  of the lenders or
arrangements will  be made  with a  suitable sub-custodian.  If assets  used  to
secure  the borrowing decrease in value, the Portfolio may be required to pledge
additional collateral to the lender in the  form of cash or securities to  avoid
liquidation of those assets.
 
    FOREIGN  INVESTMENT.   Investment in obligations  of foreign  issuers and in
foreign branches of domestic banks involves somewhat different investment  risks
than  those affecting obligations of U.S. issuers. There may be limited publicly
available information with respect to  foreign issuers, and foreign issuers  are
not  generally subject to  uniform accounting, auditing  and financial standards
and requirements comparable  to those  applicable to U.S.  companies. There  may
also  be  less  government  supervision  and  regulation  of  foreign securities
exchanges, brokers and listed companies than in the U.S. Many foreign securities
markets have substantially less volume than U.S. national securities  exchanges,
and  securities of some foreign  issuers are less liquid  and more volatile than
securities of  comparable  domestic  issuers. Brokerage  commissions  and  other
transaction  costs on foreign securities exchanges  are generally higher than in
the U.S.  Dividends and  interest paid  by  foreign issuers  may be  subject  to
withholding  and  other foreign  taxes,  which may  decrease  the net  return on
foreign  investments  as  compared  to  dividends  and  interest  paid  by  U.S.
companies.  Additional risks include future political and economic developments,
the possibility that a foreign  jurisdiction might impose or change  withholding
taxes  on income  payable with respect  to foreign securities,  and the possible
adoption of foreign governmental restrictions such as exchange controls.
 
    Prior governmental approval  for foreign investments  may be required  under
certain  circumstances in  some emerging  countries, and  the extent  of foreign
investment in certain debt securities and  domestic companies may be subject  to
limitation  in other emerging countries.  Foreign ownership limitations also may
be imposed by  the charters  of individual  companies in  emerging countries  to
prevent, among other concerns, violation of foreign investment limitations.
 
                                       16
<PAGE>
    Repatriation  of investment  income, capital  and the  proceeds of  sales by
foreign investors may require governmental registration and/or approval in  some
emerging  countries. The Portfolios could be adversely affected by delays in, or
a refusal to grant, any required governmental registration or approval for  such
repatriation.  Any  investment subject  to  such repatriation  controls  will be
considered illiquid if it appears reasonably likely that this process will  take
more than seven days.
 
    The  economies  of individual  emerging  countries may  differ  favorably or
unfavorably from the U.S. economy in  such respects as growth of gross  domestic
product,   rate  of  inflation,  currency  depreciation,  capital  reinvestment,
resource  self-sufficiency  and  balance  of  payments  position.  Further,  the
economies   of  developing  countries  generally   are  heavily  dependent  upon
international trade  and,  accordingly,  have  been, and  may  continue  to  be,
adversely  affected by trade barriers, exchange controls, managed adjustments in
relative currency values and other protectionist measures imposed or  negotiated
by  the countries with which they trade. These economies also have been, and may
continue to be, adversely affected by economic conditions in the countries  with
which they trade.
 
    With   respect  to  any  emerging  country,  there  is  the  possibility  of
nationalization, expropriation  or  confiscatory  taxation,  political  changes,
government  regulation, social instability or diplomatic developments (including
war) which could affect adversely the  economies of such countries or the  value
of  each  Portfolio's investments  in those  countries. In  addition, it  may be
difficult to obtain and enforce a judgment in a court outside of the U.S.
 
    Investments in securities of foreign  issuers are frequently denominated  in
foreign  currencies, and because each  Portfolio may temporarily hold uninvested
reserves in bank deposits in foreign  currencies, the value of each  Portfolio's
assets, as measured in U.S. dollars, may be affected favorably or unfavorably by
changes in currency rates and in exchange control regulations and the Portfolios
may incur costs in connection with conversions between various currencies.
 
    FORWARD  FOREIGN CURRENCY EXCHANGE CONTRACTS.  The Portfolios may enter into
forward foreign currency  exchange contracts  that provide for  the purchase  or
sale of an amount of a specified foreign currency at a future date. Purposes for
which  such contracts  may be  used include  protecting against  a decline  in a
foreign currency against the U.S. dollar  between the trade date and  settlement
date  when  the Portfolio  purchases or  sells securities,  locking in  the U.S.
dollar value  of  dividends declared  on  securities  held by  a  Portfolio  and
generally  protecting the U.S. dollar value  of securities held by the Portfolio
against exchange  rate  fluctuation.  Such  contracts may  also  be  used  as  a
protective measure against the effects of fluctuating rates of currency exchange
and  exchange control regulations. While such forward contracts may limit losses
to the Portfolio as a result of exchange rate fluctuation, they will also  limit
any  gains that may otherwise have been realized. See "Investment Objectives and
Policies -- Forward  Foreign Currency  Exchange Contracts" in  the Statement  of
Additional Information.
 
    As  another  means  of  reducing  the  risks  associated  with  investing in
securities denominated  in foreign  currencies, the  Portfolios may  enter  into
contracts  for the future acquisition or  delivery of foreign currencies and may
purchase foreign  currency options.  These  investment techniques  are  designed
primarily  to hedge against anticipated future  changes in currency prices, that
otherwise  might  adversely  affect  the  value  of  the  Portfolio's  portfolio
securities.  A Portfolio  will incur brokerage  fees when it  purchases or sells
futures contracts  or  options, and  it  will  be required  to  maintain  margin
deposits.  As set forth  below, futures contracts and  options entail risks, but
the Adviser believes  that use  of such contracts  and options  may benefit  the
Portfolio by diminishing currency
 
                                       17
<PAGE>
risks.  A  Portfolio will  not  enter into  any  futures contract  or  option if
immediately thereafter the value  of all the  foreign currencies underlying  its
futures  contracts and foreign currency options would exceed 10% of the value of
its total assets.  In addition, a  Portfolio may enter  into a futures  contract
only if immediately thereafter not more than 5% of its total assets are required
as deposit to secure obligations under such contracts.
 
    The  primary risks associated  with the use  of futures and  options are (i)
failure to  predict accurately  the  direction of  currency movements  and  (ii)
market  risks (e.g., lack of liquidity or lack of correlation between the change
in value  of underlying  currencies and  that of  the value  of the  Portfolio's
futures or options contracts). The risk that a Portfolio will be unable to close
out  a futures position or  options contract will be  minimized by the Portfolio
only entering into  futures contracts  or options transactions  for which  there
appears  to be  a liquid secondary  market. For more  detailed information about
futures transactions, see "Investment Objectives and Policies" in the  Statement
of Additional Information.
 
    The  Emerging Markets  Debt Portfolio  may attempt  to accomplish objectives
similar to those described above with  respect to forward and futures  contracts
for currency by means of purchasing put or call options on foreign currencies on
exchanges.  A put option gives the Portfolio the right to sell a currency at the
exercise price  until the  expiration of  the option.  A call  option gives  the
Portfolio  the right  to purchase  a currency  at the  exercise price  until the
expiration of the option.
 
    The Portfolio's Custodian  will place  cash, U.S.  government securities  or
high-grade debt securities into a segregated account of a Portfolio in an amount
equal   to  the  value  of  such  Portfolio's  total  assets  committed  to  the
consummation of forward foreign currency exchange contracts. If the value of the
securities placed  in  the  segregated  account  declines,  additional  cash  or
securities  will be placed in the account on  a daily basis so that the value of
the account will be at least equal to the amount of such Portfolio's commitments
with respect  to such  contracts.  See "Investment  Objectives and  Policies  --
Forward Currency Exchange Contracts" in the Statement of Additional Information.
 
    INVESTMENT  FUNDS.  Some  emerging countries have  laws and regulations that
currently  preclude  direct  foreign  investment  in  the  securities  of  their
companies.  However, indirect foreign investment  in the securities of companies
listed and traded  on the  stock exchanges in  these countries  is permitted  by
certain emerging countries through investment funds which have been specifically
authorized.  The Portfolios may invest in  these investment funds subject to the
provisions of the 1940 Act, and  other applicable laws as discussed below  under
"Investment  Restrictions." If a Portfolio invests in such investment funds, the
Portfolio's shareholders will  bear not  only their proportionate  share of  the
expenses  of the  Portfolio (including  operating expenses  and the  fees of the
Adviser), but  also will  indirectly  bear similar  expenses of  the  underlying
investment funds.
 
    Certain  of the investment funds referred  to in the preceding paragraph are
advised by the Adviser. These Portfolios may, to the extent permitted under  the
1940  Act  and other  applicable law,  invest  in these  investment funds.  If a
Portfolio does elect to make an investment  in such an investment fund, it  will
only purchase the securities of such investment fund in the secondary market.
 
    LOAN  PARTICIPATIONS  AND ASSIGNMENTS.   The  Emerging Markets  and Emerging
Markets Debt  Portfolios  may invest  in  fixed  rate and  floating  rate  loans
("Loans")  arranged through private negotiations  between an issuer of sovereign
debt obligations  and  one  or  more  financial  institutions  ("Lenders").  The
Portfolio's  investments in Loans  are expected in  most instances to  be in the
form of participation in  Loans ("Participations") and assignments  of all or  a
portion of Loans ("Assignments") from third parties. The Portfolio will have the
right to
 
                                       18
<PAGE>
receive  payments of principal,  interest and any  fees to which  it is entitled
only from the  Lender selling  the Participation and  only upon  receipt by  the
Lender  of the payments from the borrower. In the event of the insolvency of the
Lender selling  a Participation,  the  Portfolio may  be  treated as  a  general
creditor  of the Lender and may not  benefit from any set-off between the Lender
and the borrower. Certain Participations may be structured in a manner  designed
to  avoid purchasers of Participations  being subject to the  credit risk of the
Lender with respect to  the Participation. Even under  such a structure, in  the
event  of the Lender's  insolvency, the Lender's  servicing of the Participation
may be delayed and the assignability  of the Participation may be impaired.  The
Portfolio will acquire Participations only if the Lender interpositioned between
the Portfolio and the borrower is determined by the Adviser to be creditworthy.
 
    When the Portfolio purchases Assignments from Lenders it will acquire direct
rights  against  the  borrower on  the  Loan. However,  because  Assignments are
arranged through private negotiations between potential assignees and  potential
assignors, the rights and obligations acquired by the Portfolio as the purchaser
of  an Assignment may differ  from, and be more limited  than, those held by the
assigning Lender. Because  there is no  liquid market for  such securities,  the
Portfolio  anticipates  that such  securities could  be sold  only to  a limited
number of institutional  investors. The lack  of a liquid  secondary market  may
have  an adverse  impact on  the value  of such  securities and  the Portfolio's
ability to dispose of particular Assignments or Participations when necessary to
meet the Portfolio's liquidity needs or in response to a specific economic event
such as a deterioration in the creditworthiness  of the borrower. The lack of  a
liquid secondary market for Assignments and Participations also may make it more
difficult  for the Portfolio to assign a  value to these securities for purposes
of valuing the Portfolio's portfolio and calculating its net asset value.
 
    LOANS OF  PORTFOLIO  SECURITIES.   The  Portfolios may  lend  securities  to
brokers, dealers, domestic and foreign banks or other financial institutions for
the  purpose  of increasing  their net  investment income.  These loans  must be
secured continuously by cash or equivalent collateral, or by a letter of  credit
at  least  equal to  the  market value  of  the securities  loaned  plus accrued
interest or income. There may be a  risk of delay in recovery of the  securities
or  even loss of rights in the  collateral should the borrower of the securities
fail  financially.  Each   Portfolio  will  not   enter  into  securities   loan
transactions  exceeding in  the aggregate,  33 1/3% of  the market  value of its
total assets.  For  more  detailed  information  about  securities  lending  see
"Investment Objectives and Policies" in the Statement of Additional Information.
 
   
    MONEY  MARKET INSTRUMENTS.   Each Portfolio is permitted  to invest in money
market  instruments,  although  each  Portfolio  intends  to  stay  invested  in
securities  satisfying its primary investment objective to the extent practical.
The Portfolios may  make money  market investments pending  other investment  or
settlement  for liquidity,  or in  adverse market  conditions. The  money market
investments permitted  for the  Portfolios include:  obligations of  the  United
States government and its agencies and instrumentalities; obligations of foreign
sovereignties;   other   debt  securities;   commercial  paper   including  bank
obligations; certificates  of  deposit  (including  Eurodollar  certificates  of
deposit);  and repurchase agreements. For  more detailed information about these
money market investments,  see "Description  of Securities and  Ratings" in  the
Statement of Additional Information.
    
 
    NON-PUBLICLY   TRADED   SECURITIES,   PRIVATE   PLACEMENTS   AND  RESTRICTED
SECURITIES.  The Portfolios may invest in securities that are neither listed  on
a  stock  exchange  nor  traded  over-the-counter,  including  privately  placed
securities. Investing  in  such  unlisted emerging  country  equity  securities,
including  investments  in new  and early  stage companies,  may involve  a high
degree  of  business  and  financial   risk  that  can  result  in   substantial
 
                                       19
<PAGE>
losses.  As  a  result of  the  absence of  a  public trading  market  for these
securities, they may be  less liquid than  publicly traded securities.  Although
these  securities may be resold in privately negotiated transactions, the prices
realized from  these sales  could be  less  than those  originally paid  by  the
Portfolio,  or  less  than  what  may  be  considered  the  fair  value  of such
securities. Further, companies whose securities are not publicly traded may  not
be  subject to the  disclosure and other  investor protection requirements which
might be applicable if their securities were publicly traded. If such securities
are required  to  be  registered  under  the securities  laws  of  one  or  more
jurisdictions  before being  resold, the Portfolio  may be required  to bear the
expenses of registration.
 
    As a general matter, each Portfolio may not invest more than 15% of its  net
assets  in  illiquid  securities, including  securities  for which  there  is no
readily available secondary  market nor  more than 10%  of its  total assets  in
securities  that are  restricted from  sale to  the public  without registration
("Restricted Securities") under  the Securities  Act of 1933  (the "1933  Act").
Nevertheless,  subject  to  the  foregoing  limit  on  illiquid  securities, the
Portfolio may invest up to 25% of its total assets in Restricted Securities that
can be offered and sold to qualified institutional buyers under Rule 144A  under
that  Act ("144A Securities"). The Board of Directors has adopted guidelines and
delegated to the Adviser, subject to the supervision of the Board of  Directors,
the  daily  function  of  determining  and  monitoring  the  liquidity  of  144A
Securities. Rule 144A securities may become illiquid if qualified  institutional
buyers are not interested in acquiring the securities.
 
    REPURCHASE  AGREEMENTS.  Each Portfolio may enter into repurchase agreements
with brokers, dealers or  banks that meet the  credit guidelines established  by
the  Fund's Board of Directors. In a  repurchase agreement, the Portfolio buys a
security from a seller  that has agreed  to repurchase it  at a mutually  agreed
upon  date and price, reflecting the interest rate effective for the term of the
agreement. The term of these agreements  is usually from overnight to one  week,
and  never exceeds  one year.  Repurchase agreements  may be  viewed as  a fully
collateralized loan  of money  by the  Portfolio to  the seller.  The  Portfolio
always  receives securities with a  market value at least  equal to the purchase
price (including accrued interest) as  collateral, and this value is  maintained
during  the term  of the  agreement. If the  seller defaults  and the collateral
value declines, the Portfolio might incur a loss. If bankruptcy proceedings  are
commenced  with  respect to  the seller,  the  Portfolio's realization  upon the
collateral may  be  delayed or  limited.  The aggregate  of  certain  repurchase
agreements  and  certain  other  investments  is  limited  as  set  forth  under
"Investment Limitations."
 
    REVERSE REPURCHASE  AGREEMENTS.   The Emerging  Markets Debt  Portfolio  may
enter  into reverse  repurchase agreements  with brokers,  dealers, domestic and
foreign  banks  or  other  financial  institutions.  In  a  reverse   repurchase
agreement,  the Portfolio  sells a  security and  agrees to  repurchase it  at a
mutually agreed upon date and price, reflecting the interest rate effective  for
the  term of the agreement. It  may also be viewed as  the borrowing of money by
the  Portfolio.  The  Portfolio's  investment  of  the  proceeds  of  a  reverse
repurchase  agreement is the speculative factor known as leverage. The Portfolio
may enter into a reverse repurchase  agreement only if the interest income  from
investment  of  the  proceeds  is  greater  than  the  interest  expense  of the
transaction and the proceeds are invested for  a period no longer than the  term
of  the agreement.  The Portfolio  will maintain  with the  Custodian a separate
account with a segregated portfolio of cash, U.S. Government securities or other
liquid high grade debt obligations in an  amount at least equal to its  purchase
obligations  under these  agreements. If  interest rates  rise during  a reverse
repurchase agreement,  it  may  adversely  affect  the  Portfolio's  ability  to
maintain  a stable net asset value. The aggregate of these agreements is limited
as set forth under "Investment  Limitations." Reverse repurchase agreements  are
considered  to be  borrowings and are  subject to the  percentage limitations on
borrowings set forth in "Investment Limitations."
 
                                       20
<PAGE>
   
    RUSSIAN SECURITIES TRANSACTIONS.  The Emerging Markets Portfolio may  invest
in  equity  securities  of  Russian companies.  The  registration,  clearing and
settlement of securities transactions in Russia are subject to significant risks
not normally associated with  securities transactions in  the United States  and
other  more  developed  markets. Ownership  of  shares in  Russian  companies is
evidenced by entries in a company's share register (except where shares are held
through depositories  that  meet the  requirements  of  the 1940  Act)  and  the
issuance  of extracts from the register or,  in certain limited cases, by formal
share certificates. However, Russian  share registers are frequently  unreliable
and  the  Portfolio  could  possibly lose  its  registration  through oversight,
negligence or fraud.  Moreover, Russia  lacks a centralized  registry to  record
securities   transactions  and  registrars  located  throughout  Russia  or  the
companies  themselves  maintain  share   registers.  Registrars  are  under   no
obligation  to provide extracts to potential purchasers in a timely manner or at
all and are not necessarily subject to effective state supervision. In addition,
while registrars are liable under law for losses resulting from their errors, it
may be difficult for the Portfolio to enforce any rights it may have against the
registrar  or  issuer  of  the  securities  in  the  event  of  loss  of   share
registration.  Although Russian companies with  more than 1,000 shareholders are
required by law to employ an independent company to maintain share registers, in
practice, such companies have not always followed this law. Because of this lack
of independence of registrars,  management of a Russian  company may be able  to
exert considerable influence over who can purchase and sell the company's shares
by  illegally instructing the registrar to  refuse to record transactions on the
share register.  Furthermore, these  practices may  prevent the  Portfolio  from
investing  in the securities of certain Russian companies deemed suitable by the
Adviser and  could cause  a  delay in  the sale  of  Russian securities  by  the
Portfolio  if the  company deems  a purchaser  unsuitable, which  may expose the
Portfolio to potential loss on its investment.
    
   
    In light  of  the risks  described  above, the  Board  of Directors  of  the
Portfolio has approved certain procedures concerning the Portfolio's investments
in  Russian  securities.  Among  these  procedures  is  a  requirement  that the
Portfolio will not  invest in the  securities of a  Russian company unless  that
issuer's   registrar  has   entered  into   a  contract   with  the  Portfolio's
sub-custodian containing certain  protective conditions  including, among  other
things,  the  sub-custodian's right  to conduct  regular share  confirmations on
behalf of  the  Portfolio. This  requirement  will  likely have  the  effect  of
precluding  investments in  certain Russian  companies that  the Portfolio would
otherwise make.
    
 
   
    SHORT SALES.  The Emerging Markets Debt Portfolio may from time to time sell
securities short without limitation. A short sale is a transaction in which  the
Investment  Fund would  sell securities  it does not  own (but  has borrowed) in
anticipation of  a decline  in the  market  price of  the securities.  When  the
Portfolio  makes a short  sale, the proceeds  it receives from  the sale will be
held on behalf of a broker until the Portfolio replaces the borrowed securities.
To deliver  the securities  to the  buyer, the  Portfolio will  need to  arrange
through  a broker to borrow the securities and, in so doing, the Investment Fund
will become obligated to replace the  securities borrowed at their market  price
at  the time of replacement, whatever that  price may be. The Portfolio may have
to pay a premium to borrow the securities and must pay any dividends or interest
payable on the securities until they are replaced.
    
 
    The Portfolio's obligation to replace the securities borrowed in  connection
with  a short sale will be secured  by collateral deposited with the broker that
consists of cash, U.S.  government securities or other  liquid, high grade  debt
obligations.  In addition, the Portfolio will place in a segregated account with
its Custodian an amount of cash, U.S. government securities or other liquid high
grade debt obligations equal to the  difference, if any, between (1) the  market
value  of the securities sold at the time they were sold short and (2) any cash,
U.S.
 
                                       21
<PAGE>
government securities or other liquid  high grade debt obligations deposited  as
collateral  with the broker in connection with the short sale (not including the
proceeds of the short sale). Short sales by the Investment Fund involve  certain
risks  and special considerations. Possible losses  from short sales differ from
losses that could be incurred from a purchase of a security, because losses from
short sales may be unlimited, whereas  losses from purchases can equal only  the
total amount invested.
 
    STOCK  OPTION  AND INDEX  FUTURES  CONTRACTS.   Each  Portfolio may  seek to
increase its return or may hedge all  or a portion of its portfolio  investments
through  stock  options  and  stock  index  futures  contracts  with  respect to
securities in  which  the Portfolio  may  invest. There  currently  are  limited
options  and stock index futures markets in emerging countries and the nature of
the strategies adopted by the Adviser  and the extent to which those  strategies
are  used will depend on the development of stock option and stock index futures
contracts by emerging country stock  exchanges. Each Portfolio will only  engage
in  transactions in  stock options and  stock index futures  contracts which are
traded on a recognized securities or futures exchange.
 
    The Emerging  Markets Debt  Portfolio may  write (i.e.,  sell) covered  call
options  on  securities  and loan  participations  and assignments  held  in its
portfolio, which options  give the  purchaser the  right to  buy the  underlying
security,  loan  participation  or assignment  covered  by the  option  from the
Portfolio at the stated  exercise price. A "covered"  call option means that  so
long  as the Portfolio is obligated as the writer of the option, it will own (i)
the underlying security, loan participation or assignment subject to the option,
or (ii)  securities  convertible or  exchangeable  without the  payment  of  any
consideration into the security, loan participation or assignment subject to the
option.  As a matter of operating policy,  the aggregate value of the underlying
securities, loan participations and assignments on which options will be written
at any one  time will not  exceed 5% of  the total assets  of the Portfolio.  In
addition,  as a matter of  operating policy, the Portfolio  may purchase put and
call options on securities, loan participations or assignments.
 
    The Portfolio  will  receive a  premium  from writing  call  options,  which
increases  the Portfolio's return on the underlying security, loan participation
or assignment in the event the option expires unexercised or is closed out at  a
profit.  By writing a call,  the Portfolio will limit  its opportunity to profit
from  an  increase  in  the  market  value  of  the  underlying  security,  loan
participation  or assignment above the exercise price  of the option for as long
as the Portfolio's obligation as writer  of the option continues. Thus, in  some
periods  the  Portfolio will  receive  less total  return  and in  other periods
greater total  return from  writing  covered call  options  than it  would  have
received from its underlying securities, loan participations and assignments had
it  not written call options. The Portfolio pays a premium to purchase an option
and the risk assumed by the Portfolio when it purchases an option is the loss of
this premium. Because  the price of  an option tends  to move with  that of  its
underlying  security, if  the Portfolio is  to make  a profit, the  price of the
underlying security, loan participation or assignment must change and the change
must be sufficient to cover the premiums and commissions paid. A price change in
the security, loan participation  or assignment underlying  the option does  not
assure  a profit because  prices in the  options markets may  not always reflect
such change.
 
    The Emerging Markets Debt Portfolio may purchase and sell indexed  financial
futures  contracts. An indexed futures contract is  an agreement to take or make
delivery of an amount of cash equal  to the difference between the value of  the
index  at the beginning and at the end of the contract period. Successful use of
indexed futures will be  subject to the Adviser's  ability to predict  correctly
movements  in the  direction of  the relevant debt  market. No  assurance can be
given that the Adviser's judgment in this respect will be correct.
 
                                       22
<PAGE>
    The Portfolio may sell indexed  financial futures contracts in  anticipation
of  or during a market decline to attempt to offset the decrease in market value
of securities in its portfolio that  might otherwise result. When the  Portfolio
is  not fully  invested in  emerging country  debt securities  and anticipates a
significant market advance,  it may purchase  indexed futures in  order to  gain
rapid  market exposure that may in part or entirely offset increases in the cost
of securities that it  intends to purchase. In  a substantial majority of  these
transactions,  the Portfolio will  purchase such securities  upon termination of
the futures position but,  under unusual market  conditions, a futures  position
may be terminated without the corresponding purchase of debt securities.
 
    STRUCTURED  SECURITIES.   The Emerging Markets  Debt Portfolio  may invest a
portion of its assets in entities organized and operated solely for the  purpose
of  restructuring the investment characteristics  of sovereign debt obligations.
This type of restructuring involves the deposit with, or purchase by, an entity,
such as a  corporation or trust,  of specified instruments  (such as  commercial
bank  loans or  Brady Bonds)  and the  issuance by  that entity  of one  or more
classes of  securities  ("Structured  Securities") backed  by,  or  representing
interests  in,  the  underlying instruments.  The  cash flow  on  the underlying
instruments may be apportioned among  the newly issued Structured Securities  to
create  securities with  different investment  characteristics, such  as varying
maturities, payment priorities and interest  rate provisions, and the extent  of
the  payments made  with respect  to Structured  Securities is  dependent on the
extent of  the  cash flow  on  the underlying  instruments.  Because  Structured
Securities  of  the  type in  which  the  Portfolio anticipates  it  will invest
typically involve no  credit enhancement,  their credit risk  generally will  be
equivalent  to that of the underlying instruments. The Portfolio is permitted to
invest in  a class  of  Structured Securities  that  is either  subordinated  or
unsubordinated to the right of payment of another class. Subordinated Structured
Securities   typically  have  higher  yields  and  present  greater  risks  than
unsubordinated Structured Securities. Structured  Securities are typically  sold
in  private placement  transactions, and  there currently  is no  active trading
market for Structured Securities.
 
    TEMPORARY INVESTMENTS.  During periods in which the Adviser believes changes
in economic, financial or political  conditions make it advisable, the  Emerging
Markets  Portfolio may reduce  its holdings in equity  and other securities, and
the Emerging Markets Debt Portfolio may reduce its holdings in emerging  country
debt securities, for temporary defensive purposes, and the Portfolios may invest
in certain short-term (less than twelve months to maturity) and medium-term (not
greater  than five  years to  maturity) debt  securities or  may hold  cash. The
short-term and medium-term  debt securities  in which the  Portfolio may  invest
consist  of (a) obligations  of the U.S. or  emerging country governments, their
respective agencies or instrumentalities; (b) bank deposits and bank obligations
(including certificates of deposit, time  deposits and bankers' acceptances)  of
U.S.  or emerging country  banks denominated in any  currency; (c) floating rate
securities  and  other  instruments  denominated  in  any  currency  issued   by
international development agencies; (d) finance company and corporate commercial
paper  and  other short-term  corporate debt  obligations  of United  States and
emerging country corporations meeting the Portfolio's credit quality  standards;
and (e) repurchase agreements with banks and broker-dealers with respect to such
securities.  For temporary defensive  purposes, the Portfolios  intend to invest
only in short-term and medium-term debt securities that the Adviser believes  to
be  of high quality, i.e., subject to relatively low risk of loss of interest or
principal (there  is currently  no rating  system for  debt securities  in  most
emerging countries).
 
    WHEN-ISSUED  AND DELAYED DELIVERY  SECURITIES.  Each  Portfolio may purchase
securities on a  when-issued or  delayed delivery basis.  In such  transactions,
instruments  are bought with payment and delivery  taking place in the future in
order to secure what is considered to  be an advantageous yield or price at  the
time of the
 
                                       23
<PAGE>
transaction.  Each Portfolio will maintain with the Custodian a separate account
with a segregated portfolio of high  grade debt securities or equity  securities
or cash in an amount at least equal to these commitments. The payment obligation
and  the interest  rates that will  be received are  each fixed at  the time the
Portfolio enters into the  commitment and no interest  accrues to the  Portfolio
until  settlement. Thus,  it is possible  that the  market value at  the time of
settlement could be  higher or  lower than the  purchase price  if, among  other
factors, the general level of interest rates has changed. It is a current policy
of  each Portfolio not to enter into when-issued commitments or delayed delivery
securities exceeding,  in  the  aggregate,  15%  of  the  market  value  of  the
Portfolio's total assets less liabilities, other than the obligations created by
these commitments.
 
                             INVESTMENT LIMITATIONS
 
    Each  Portfolio is  a non-diversified  portfolio under  the 1940  Act, which
means that the Portfolio is not limited by the 1940 Act in the proportion of its
assets that may be invested  in the obligations of  a single issuer. Thus,  each
Portfolio  may invest a greater proportion of  its assets in the securities of a
smaller number of issuers and, as a result, will be subject to greater risk with
respect to its portfolio securities.  However, each Portfolio intends to  comply
with  the diversification requirements  imposed by the  Internal Revenue Code of
1986, as  amended, for  qualification  as a  regulated investment  company.  See
"Taxes"  below  and  "Investment  Limitations" in  the  Statement  of Additional
Information.
 
   
    Each Portfolio  operates  under  certain investment  restrictions  that  are
deemed  fundamental limitations and may be changed only with the approval of the
holders of a  majority of  the Portfolio's outstanding  shares. See  "Investment
Limitations"  in  the Statement  of  Additional Information.  In  addition, each
Portfolio operates  under  certain  non-fundamental  investment  limitations  as
described  below and in the Statement  of Additional Information. Each Portfolio
may not  (i) enter  into repurchase  agreements  with more  than seven  days  to
maturity  if, as a result, more than 15%  of the market value of the Portfolio's
net assets would be invested in such repurchase agreements and other investments
for which market  quotations are not  readily available or  which are  otherwise
illiquid;  (ii) borrow money,  except from banks  for extraordinary or emergency
purposes, and then only  in amounts up  to 10% of the  value of the  Portfolio's
total  assets taken  at cost  at the time  of borrowing;  or purchase securities
while borrowings exceed 5% of its total assets, except the Emerging Markets Debt
Portfolio is not subject to such limits  on borrowing and may borrow from  banks
and  other entities  in amounts  not in excess  of 33  1/3% of  its total assets
(including the  amount borrowed)  less liabilities;  (iii) mortgage,  pledge  or
hypothecate  any assets except in connection  with any such borrowing in amounts
up to 10% of the value of the  Portfolio's net assets at the time of  borrowing;
(iv)  invest in fixed time deposits with a duration of over seven calendar days;
or (v) invest in fixed time deposits  with a duration of from two business  days
to seven calendar days if more than 10% of the Portfolio's total assets would be
invested in these deposits.
    
 
   
LOCAL ADMINISTRATOR FOR THE EMERGING MARKETS PORTFOLIO
    
 
   
    The  Emerging Markets  Portfolio is required  under Brazilian law  to have a
local administrator in Brazil. Unibanco-Uniao (the "Brazilian Administrator"), a
Brazilian corporation, acts as the Portfolio's Brazilian administrator  pursuant
to  an agreement with  the Portfolio (the  "Brazilian Administration Agreement).
Under  the  Brazilian  Administration  Agreement,  the  Brazilian  Administrator
performs   various  services   for  the   Portfolio,  including   effecting  the
registration of the Portfolio's foreign capital with the Central Bank of  Brazil
effecting   all  foreign  exchange  transactions   related  to  the  Portfolio's
investments in Brazil and obtaining all approvals required for the Portfolio  to
make  remittances of income  and capital gains  and for the  repatriation of the
    
 
                                       24
<PAGE>
   
Portfolio's investments  pursuant  to  Brazilian  law.  For  its  services,  the
Brazilian Administrator is paid an annual fee equal to 0.125% of the Portfolio's
average weekly net assets invested in Brazil, paid monthly. The principal office
of  the Brazilian Administrator  is located at Avenida  Eusebio Matoso, 891, Sao
Paulo, S.P, Brazil.  The Brazilian Administration  Agreement is terminable  upon
six  months' notice by either party. The Brazilian Administrator may be replaced
only by an entity authorized to act as a joint manager of a managed portfolio of
bonds and securities under Brazilian law.
    
 
   
    The Emerging Markets  Portfolio is required  under Colombian law  to have  a
local administrator in Colombia. CitiTrust S.A. (the "Colombian Administrator"),
a  Colombian  Trust Company,  acts  as the  Portfolio's  Colombian administrator
pursuant to an agreement with  the Portfolio (the "Colombian Agreement").  Under
the  Colombian Agreement, the Colombian  Administrator performs various services
for the  Portfolio,  including effecting  the  registration of  the  Portfolio's
foreign  capital  with  the  Central Bank  of  Colombia,  effecting  all foreign
exchange transactions related  to the  Portfolio's investments  in Colombia  and
obtaining all approvals required for the Portfolio to make remittances of income
and  capital  gains  and for  the  repatriation of  the  Portfolio's investments
pursuant to Colombian law. For its services, the Colombian Administrator is paid
an annual fee of $1000  plus .20% per transaction.  The principal office of  the
Colombian  Administrator is  located at Sociedad  Fiduciaria International S.A.,
8-89, Piso  2,  Santa  Fe  de  Bogota,  Colombia.  The  Colombian  Agreement  is
terminable upon 30 days' notice by either party. The Colombian Administrator may
be  replaced only by an entity authorized to act as a joint manager of a managed
portfolio of bonds and securities under Colombian law.
    
 
                             MANAGEMENT OF THE FUND
 
   
    INVESTMENT ADVISER.  Morgan Stanley Asset Management Inc. is the  Investment
Adviser  and Administrator of the  Fund and each of  the Portfolios. The Adviser
provides investment advice  and portfolio  management services,  pursuant to  an
Investment  Advisory Agreement  and, subject  to the  supervision of  the Fund's
Board  of  Directors,  makes  each  of  the  Portfolio's  day-to-day  investment
decisions,  arranges for the  execution of portfolio  transactions and generally
manages each of the Portfolio's investments. The Adviser is entitled to  receive
from  each Portfolio an  annual management fee, payable  quarterly, equal to the
percentage of average daily  net assets set forth  in the table below.  However,
the Adviser has agreed to a reduction in the fees payable to it and to reimburse
the Portfolio, if necessary, if such fees would cause the total annual operating
expenses  of either  Portfolio to exceed  the respective  percentages of average
daily net assets set forth in the table below.
    
 
   
<TABLE>
<CAPTION>
                                                  MAXIMUM TOTAL ANNUAL
                                                        OPERATING
                                                   EXPENSES AFTER FEE
                                                         WAIVERS
                                  MANAGEMENT    -------------------------
          PORTFOLIO                   FEE        CLASS A         CLASS B
- ------------------------------    -----------   ---------       ---------
<S>                               <C>           <C>             <C>
Emerging Markets Portfolio             1.25%       1.75%           2.00%
Emerging Markets Debt
 Portfolio                             1.00%       1.75%           2.00%
</TABLE>
    
 
   
    The Adviser, with  principal offices  at 1221  Avenue of  the Americas,  New
York,  New  York  10020,  conducts a  worldwide  portfolio  management business,
providing a broad  range of portfolio  management services to  customers in  the
United  States and abroad. At December 31,  1995, the Adviser, together with its
affiliated   asset   management   companies,   managed   investments    totaling
approximately  $57.4 billion, including approximately $41.9 billion under active
management and  $15.5  billion as  Named  Fiduciary or  Fiduciary  Adviser.  See
"Management of the Fund" in the Statement of Additional Information.
    
 
                                       25
<PAGE>
    PORTFOLIO  MANAGERS.  The following  individuals have primary responsibility
for the Portfolio indicated below.
 
    EMERGING MARKETS  PORTFOLIO --  MADHAV  DHAR.   Madhav  Dhar is  a  Managing
Director  of Morgan Stanley.  He joined the  Adviser in 1984  to focus on global
asset allocation and investment  strategy and now  heads the Adviser's  emerging
markets  group and serves  as the group's principal  Portfolio Manager. Mr. Dhar
also coordinates  the Adviser's  developing country  funds effort  and has  been
involved  in the launching of  the Adviser's country funds.  He is a Director of
the  Morgan  Stanley  Emerging  Markets  Fund,  Inc.  (a  closed-end  investment
company).  He holds a B.S. (honors)  from St. Stephens College, Delhi University
(India), and an M.B.A. from Carnegie-Mellon University. Mr. Dhar has had primary
responsibility for managing the Portfolio's assets since inception.
 
    EMERGING MARKETS  DEBT PORTFOLIO  --  PAUL GHAFFARI.    Paul Ghaffari  is  a
Principal  of  Morgan Stanley.  He joined  the Adviser  in June  1993 as  a Vice
President and Portfolio  Manager for  the Morgan Stanley  Emerging Markets  Debt
Fund  (a  closed-end  investment company).  Prior  to joining  the  Adviser, Mr.
Ghaffari was  a Vice  President in  the Fixed  Income Division  of the  Emerging
Markets  Sales and Trading Department  at Morgan Stanley. From  1983 to 1992, he
worked in LDC Sales  and Trading Department  and the Mortgage-Backed  Securities
Department  at J.P. Morgan &  Co. Inc. and worked  in the Treasury Department at
the Morgan Guaranty Trust  Co. He holds a  B.A. in International Relations  from
Pamona  College and an  M.S. in Foreign Service  from Georgetown University. Mr.
Ghaffari has  had primary  responsibility for  managing the  Portfolio's  assets
since inception.
 
    ADMINISTRATOR.    The Adviser  also  provides the  Fund  with administrative
services pursuant to  an Administration Agreement.  The services provided  under
the  Administration Agreement are subject to the supervision of the Officers and
the Board of  Directors of  the Fund  and include  day-to-day administration  of
matters  related  to the  corporate existence  of the  Fund, maintenance  of its
records, preparation of reports, supervision of the Fund's arrangements with its
custodian,  and  assistance  in  the  preparation  of  the  Fund's  registration
statements  under  federal and  state  laws. The  Administration  Agreement also
provides that  the Administrator,  through  its agents,  will provide  the  Fund
dividend  disbursing and  transfer agent  services. For  its services  under the
Administration Agreement, the Fund  pays the Adviser a  monthly fee which on  an
annual basis equals 0.15% of the average daily net assets of each Portfolio.
 
   
    Under  an agreement between  the Adviser and The  Chase Manhattan Bank, N.A.
("Chase"), Chase  provides certain  administrative services  to the  Fund. In  a
merger  completed on September 1, 1995, Chase succeeded to all of the rights and
obligations under the  U.S. Trust Administration  Agreement between the  Adviser
and  United States Trust Company  of New York ("U.S.  Trust"), pursuant to which
U.S. Trust had agreed  to provide certain administrative  services to the  Fund.
Pursuant to a delegation clause in the U.S. Trust Administration Agreement, U.S.
Trust  delegated  its  administration  responsibilities  to  Chase  Global Funds
Services Company  ("CGFSC"), formerly  known as  Mutual Funds  Service  Company,
which  after the merger with Chase is a subsidiary of Chase and will continue to
provide certain administrative services to the Fund. The Adviser supervises  and
monitors  administrative services provided by CGFSC. The services provided under
the Administration Agreement  and the  U.S. Trust  Administration Agreement  are
also subject to the supervision of the Board of Directors of the Fund. The Board
of  Directors of the Fund has approved the provision of services described above
pursuant to  the  Administration Agreement  and  the U.S.  Trust  Administration
Agreement as being in the best interest of the
    
 
                                       26
<PAGE>
Fund.  CGFSC's  business address  is  73 Tremont  Street,  Boston, Massachusetts
02108-3913. For additional information regarding the Administration Agreement or
the U.S. Trust  Administration Agreement, see  "Management of the  Fund" in  the
Statement of Additional Information.
 
    DIRECTORS  AND OFFICERS.  Pursuant to  the Fund's Articles of Incorporation,
the Board of Directors  decides upon matters of  general policy and reviews  the
actions  of the Fund's  Adviser, Administrator and  Distributor. The Officers of
the Fund conduct and supervise its daily business operations.
 
   
    DISTRIBUTOR.   Morgan Stanley  serves as  the exclusive  Distributor of  the
shares  of  the Fund.  Under its  Distribution Agreement  with the  Fund, Morgan
Stanley sells  shares  of each  Portfolio  upon the  terms  and at  the  current
offering  price described in this Prospectus. Morgan Stanley is not obligated to
sell any certain number of shares of any Portfolio.
    
 
   
    The Portfolios currently offer  only the classes of  shares offered by  this
Prospectus.  The Portfolio may in the future offer one or more classes of shares
with features, distribution expenses or  other expenses that are different  from
those of the classes currently offered.
    
 
   
    The  Fund has  adopted a Plan  of Distribution  with respect to  the Class B
shares for each  Portfolio pursuant to  Rule 12b-1  under the 1940  Act (each  a
"Plan").  Under  each Plan,  the  Distributor is  entitled  to receive  from the
Portfolios a distribution  fee, which is  accrued daily and  paid quarterly,  of
0.25%  of the Class B  shares' average daily net  assets on an annualized basis.
The Distributor  expects  to  reallocate  most of  its  fee  to  its  investment
representatives.  The Distributor may, in its discretion, voluntarily waive from
time to  time all  or  any portion  of  its distribution  fee  and each  of  the
Distributor  and the Adviser is free to  make additional payments out of its own
assets to promote the  sale of Fund shares,  including payments that  compensate
financial institutions for distribution services or shareholder services.
    
 
   
    Each Plan is designed to compensate the Distributor for its services, not to
reimburse  the Distributor for its expenses,  and the Distributor may retain any
portion of the fee that it does not expend in fulfillment of its obligations  to
the Fund.
    
 
   
    PAYMENTS  TO  FINANCIAL INSTITUTIONS.   The  Adviser  or its  affiliates may
compensate certain financial institutions for the continued investment of  their
customers'  assets in the  Emerging Markets Portfolio pursuant  to the advice of
such financial institutions. These payments will be made directly by the Adviser
or its affiliates from their assets, and will not be made from the assets of the
Fund or  by  the  assessment  of  a  sales  charge  on  shares.  Such  financial
institutions may also perform certain shareholder or recordkeeping services that
would  otherwise be performed  by CGFSC. The  Adviser may elect  to enter into a
contract to pay the financial institutions for such services.
    
 
    EXPENSES.  Each Portfolio is responsible  for payment of certain other  fees
and  expenses (including  organizational costs,  legal fees,  accountant's fees,
custodial fees, and printing and mailing costs) specified in the  Administration
and Distribution Agreements.
 
                               PURCHASE OF SHARES
 
   
    Class A and Class B shares of each Portfolio may be purchased, without sales
commission,  at the net asset  value per share next  determined after receipt of
the purchase order by the Portfolio. See "Valuation of Shares."
    
 
                                       27
<PAGE>
   
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
    
 
   
    For an account for either  Portfolio opened on or  after January 2, 1996  (a
"New  Account"), the  minimum initial  investment and  minimum account  size are
$500,000 for Class A  shares and $100,000 for  Class B shares. Managed  Accounts
may  purchase  Class  A shares  without  being  subject to  any  minimum initial
investment or  minimum  account  size  requirements  for  a  Portfolio  account.
Officers  of the Adviser  and its affiliates  are subject to  the minimums for a
Portfolio account, except they may purchase Class B shares subject to a  minimum
initial investment and minimum account size of $5,000 for a Portfolio account.
    
 
   
    If the value of a New Account containing Class A shares falls below $500,000
(but  remains at  or above $100,000)  because of  shareholder redemption(s), the
Fund will  notify  the shareholder,  and  if  the account  value  remains  below
$500,000  (but remains at or above $100,000) for a continuous 60-day period, the
Class A  shares in  such account  will convert  to Class  B shares  and will  be
subject  to the distribution  fee and other  features applicable to  the Class B
shares. The Fund, however,  will not convert  Class A shares  to Class B  shares
based  solely upon  changes in  the market  that reduce  the net  asset value of
shares. Under  current tax  law, conversions  between share  classes are  not  a
taxable event to the shareholder.
    
 
   
    Shares  in a Portfolio account opened prior  to January 2, 1996 (a "Pre-1996
Account") were  designated  Class A  shares  on January  2,  1996. Shares  in  a
Pre-1996  Account  with  a  value  of  $100,000 or  more  on  March  1,  1996 (a
"Grandfathered Class A Account") remained  Class A shares regardless of  account
size  thereafter. Except for shares  in a Managed Account,  shares in a Pre-1996
Account with a value of  less than $100,000 on  March 1, 1996 (a  "Grandfathered
Class  B Account") converted to  Class B shares on  March 1, 1996. Grandfathered
Class A Accounts and Managed Accounts are not subject to conversion from Class A
shares to Class B shares.
    
 
   
    Investors may also invest in the  Fund by purchasing shares through a  trust
department, broker, dealer, agent, financial planner, financial services firm or
investment  adviser.  An  investor  may  be  charged  an  additional  service or
transaction fee by that institution. The minimum investment levels may be waived
at the discretion  of the  Adviser for (i)  certain employees  and customers  of
Morgan  Stanley  or  its  affiliates  and  certain  trust  departments, brokers,
dealers, agents,  financial  planers,  financial services  firms  or  investment
advisers  that  have  entered  into  an agreement  with  Morgan  Stanley  or its
affiliates; and (ii) retirement and deferred compensation plans and trusts, used
to fund such  plans, including,  but not limited  to, those  defined in  Section
401(a),  403(b) or  457 of the  Internal Revenue  Code of 1986,  as amended, and
"rabbi trusts".  The  Fund  reserves  the  right  to  modify  or  terminate  the
conversion  features of  the shares  as stated above  at any  time upon 60-days'
notice to shareholders.
    
 
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
 
   
    If the value of  a New Account falls  below $100,000 because of  shareholder
redemption(s),  the Fund will  notify the shareholder, and  if the account value
remains below  $100,000 for  a  continuous 60-day  period,  the shares  in  such
account  are subject to redemption  by the Fund and,  if redeemed, the net asset
value of  such  shares will  be  promptly paid  to  the shareholder.  The  Fund,
however,  will not redeem  shares based solely  upon changes in  the market that
reduce the net asset value of shares.
    
 
   
    For purposes of redemptions by the Fund, the foregoing minimum account  size
requirements  do not  apply to  New Accounts containing  Class B  shares held by
officers of the Adviser or its affiliates. However, if the value of such account
held by an officer of the Adviser  or its affiliates falls below $5,000  because
of shareholder
    
 
                                       28
<PAGE>
redemptions(s),  the Fund will notify the  shareholder, and if the account value
remains $5,000 for a  continuous 60-day period, the  shares in such account  are
subject  to redemption by the Fund and, if redeemed, the net asset value of such
shares will be promptly paid to the shareholder.
 
   
    Grandfathered Class A Accounts, Grandfathered  Class B Accounts and  Managed
Accounts are not subject to involuntary redemption.
    
 
   
    The  Fund  reserves  the  right  to  modify  or  terminate  the  involuntary
redemption features of  the shares  as stated above  at any  time upon  60-days'
notice to shareholders.
    
 
CONVERSION FROM CLASS B TO CLASS A SHARES
 
   
    If the value of Class B shares in a Portfolio account increases, whether due
to  shareholder share  purchases or  market activity,  to $500,000  or more, the
Class B shares  will convert  to Class  A shares.  Under current  tax law,  such
conversion  is not a taxable event to  the shareholder. Class A shares converted
from Class B shares  are subject to the  same minimum account size  requirements
that  are applicable to New Accounts containing Class A shares, as stated above.
The Fund reserves the  right to modify or  terminate this conversion feature  at
any time upon 60-days' notice to shareholders.
    
 
   
INITIAL PURCHASES DIRECTLY FROM THE FUND
    
 
   
    The  Fund's determination of an investor's eligibility to purchase shares of
a given class  will take precedence  over the investor's  selection of a  class.
Assuming  the investor is eligible for the  class, the Fund will select the most
favorable class for the investor, if the investor has not done so.
    
 
   
1) BY CHECK.   An account may  be opened  by completing and  signing an  Account
   Registration  Form, and mailing  it, together with  a check ($500,000 minimum
   for Class A shares of each Portfolio and $100,000 for Class B shares of  each
   Portfolio,  with certain exceptions  for Morgan Stanley  employees and select
   customers) payable to "Morgan Stanley Institutional Fund, Inc. --  [portfolio
   name]", to:
    
 
   
      Morgan Stanley Institutional Fund, Inc.
      P.O. Box 2798
      Boston, Massachusetts 02208-2798
    
 
   
     Payment will  be accepted only  in U.S. dollars,  unless prior approval for
  payment by  other currencies  is given  by the  Fund. The  Portfolio(s) to  be
  purchased should be designated on the Account Registration Form. For purchases
  by  check,  the Fund  is  ordinarily credited  with  Federal Funds  within one
  business day. Thus your purchase of shares by check is ordinarily credited  to
  your  account  at the  net asset  value per  share of  each of  the Portfolios
  determined on the next business day after receipt.
    
 
   
2) BY FEDERAL  FUNDS WIRE.   Purchases  may be  made by  having your  bank  wire
   Federal  Funds to the Fund's bank account.  In order to ensure prompt receipt
   of your Federal Funds Wire, it is important that you follow these steps:
    
 
   
A.  Telephone  the Fund  (toll free: 1-800-548-7786)  and provide  us with  your
    name,  address,  telephone  number, Social  Security  or  Tax Identification
    Number, the  portfolio(s) selected,  the class  selected, the  amount  being
    wired,  and by  which bank.  We will  then provide  you with  a Fund account
    number. (Investors with existing accounts should also notify the Fund  prior
    to wiring funds.)
    
 
                                       29
<PAGE>
   
B.    Instruct  your  bank to  wire  the  specified amount  to  the  Fund's Wire
    Concentration Bank Account (be  sure to have your  bank include the name  of
    the  portfolio(s)  selected,  the  class  selected  and  the  account number
    assigned to you) as follows:
    
 
   
    Chase Manhattan Bank, N.A.
    One Manhattan Plaza
    New York, NY 10081-1000
    ABA#021000021
    DDA# 910-2-733293
    Attn: Morgan Stanley Institutional Fund, Inc.
    Ref: (Portfolio name, your account number, your account name)
    
 
   
    Please call the Fund at 1-800-548-7786 prior to wiring funds.
    
 
   
C.  Complete and sign the Account  Registration Form and mail it to the  address
    shown thereon.
    
 
   
  Purchase  orders for shares of each Portfolio  which are received prior to the
  regular close of the NYSE (currently 4:00 p.m. Eastern Time) will be  executed
  at  the price computed  on the date of  receipt as long  as the Transfer Agent
  receives payment by check or  in Federal Funds prior  to the regular close  of
  the NYSE on such day.
    
 
   
  Federal Funds purchase orders will be accepted only on a day on which the Fund
  and Chase (the "Custodian Bank") are open for business. Your bank may charge a
  service fee for wiring Federal funds.
    
 
   
3) BY  BANK WIRE.   The  same procedure outlined  under "By  Federal Funds Wire"
   above must be  followed in  purchasing shares  by bank  wire. However,  money
   transferred  by bank wire may or may  not be converted into Federal Funds the
   same day, depending on the time the  money is received and the bank  handling
   the wire. Prior to such conversion, an investor's money will not be invested.
   Your bank may charge a service fee for wiring funds.
    
 
ADDITIONAL INVESTMENTS
 
   
    You  may  add to  your account  at any  time (minimum  additional investment
$1,000, except  for  automatic  reinvestment  of  dividends  and  capital  gains
distributions for which there are no minimums) by purchasing shares at net asset
value  by mailing a check to the  Fund (payable to "Morgan Stanley Institutional
Fund Inc. -- [portfolio name]") at the above address or by wiring monies to  the
Custodian  Bank as outlined above.  It is very important  that your account name
and portfolio be specified in the letter  or wire to ensure proper crediting  to
your  account. In order to  ensure that your wire  orders are invested promptly,
you are  requested to  notify  one of  the  Fund's representatives  (toll  free:
1-800-548-7786)  prior to the wire date.  Additional investments will be applied
to purchase additional  shares in  the same  class held  by a  shareholder in  a
Portfolio account.
    
 
OTHER PURCHASE INFORMATION
 
    The  purchase price of the  Class A and Class B  shares of the Portfolios is
the net asset value next determined after the order is received. See  "Valuation
of  Shares." An order received prior to the  regular close of the New York Stock
Exchange ("NYSE"), which is currently 4:00  p.m. Eastern Time, will be  executed
at the price
 
                                       30
<PAGE>
computed  on the date of  receipt; an order received  after the regular close of
the NYSE will be executed at the price computed on the next day the NYSE is open
as long as  the Transfer Agent  receives payment  by check or  in Federal  Funds
prior to the regular close of the NYSE on such day.
 
    Although  the legal rights of Class A  and Class B shares will be identical,
the different expenses borne  by each class will  result in different net  asset
values  and dividends. The net  asset value of Class  B shares will generally be
lower than the net asset value of Class A shares as a result of the distribution
expense charged to Class B shares. It  is expected, however, that the net  asset
value  per share of the two classes  will tend to converge immediately after the
recording of dividends  which will  differ by  approximately the  amount of  the
distribution expense accrual differential between the classes.
 
    In  the interest  of economy and  convenience, and because  of the operating
procedures of the Fund, certificates representing shares of the Portfolios  will
not  be issued. All shares  purchased are confirmed to  you and credited to your
account on the Fund's books  maintained by the Adviser  or its agents. You  will
have  the  same  rights  and  ownership  with  respect  to  such  shares  as  if
certificates had been issued.
 
    To ensure that checks are collected by the Fund, withdrawals of  investments
made  by check are  not presently permitted  until payment for  the purchase has
been received,  which may  take up  to eight  business days  after the  date  of
purchase.  As a  condition of this  offering, if  a purchase is  canceled due to
nonpayment or because your check does not clear, you will be responsible for any
loss the Fund or its  agents incur. If you are  already a shareholder, the  Fund
may  redeem shares from your account(s) to  reimburse the Fund or its agents for
any loss. In addition,  you may be prohibited  or restricted from making  future
purchases in the Fund.
 
    Investors  may  also invest  in the  Fund by  purchasing shares  through the
Distributor.
 
   
EXCESSIVE TRADING
    
 
   
    Frequent  trades  involving  either   substantial  portfolio  assets  or   a
substantial  portion of your  account or accounts controlled  by you can disrupt
management of a portfolio and raise its expenses. Consequently, in the  interest
of  all the stockholders of each  Portfolio and the Portfolio's performance, the
Fund may in its discretion bar  a stockholder that engages in excessive  trading
of  shares of any class  of a portfolio from further  purchases of shares of the
Fund for an indefinite period. The  Fund considers excessive trading to be  more
than  one purchase and sale involving shares of the same class of a portfolio of
the Fund  within  any  120-day  period. As  an  example,  exchanging  shares  of
portfolios of the Fund as follows amounts to excessive trading: exchanging Class
A shares of Portfolio A for Class A shares of Portfolio B, then exchanging Class
A  shares of Portfolio B for Class A  shares of Portfolio C and again exchanging
Class A shares of Portfolio C for Class A shares of Portfolio B within a 120-day
period. Two  types  of transactions  are  exempt from  these  excessive  trading
restrictions:  (1) trades exclusively  between money market  portfolios; and (2)
trades done  in  connection  with  an asset  allocation  service,  such  as  TFM
Accounts, managed or advised by MSAM and/or any of its affiliates.
    
 
                              REDEMPTION OF SHARES
 
   
    You  may  withdraw all  or  any portion  of the  amount  in your  account by
redeeming shares at any time. Please note  that purchases made by check are  not
permitted to be redeemed until payment of the purchase has been collected, which
may  take up to eight business days after purchase. The Fund will redeem Class A
shares or Class  B shares of  each Portfolio  at the next  determined net  asset
value of shares of the applicable class. On days
    
 
                                       31
<PAGE>
   
that  both the NYSE and the Custodian Bank  are open for business, the net asset
value per share of each of the Portfolios is determined at the regular close  of
trading of the NYSE (currently 4:00 p.m. Eastern Time). Shares of the Portfolios
may  be redeemed  by mail or  telephone. No  charge is made  for redemption. Any
redemption proceeds may be more or less  than the purchase price of your  shares
depending on, among other factors, the market value of the investment securities
held by the Portfolio.
    
 
   
BY MAIL
    
 
   
    Each  Portfolio will redeem its  Class A or Class B  shares at the net asset
value determined on the date the request is received, if the request is received
in "good order" before  the regular close  of the NYSE.  Your request should  be
addressed  to Morgan  Stanley Institutional Fund,  Inc., P.O.  Box 2798, Boston,
Massachusetts 02208-2798, except that deliveries by overnight courier should  be
addressed  to Morgan  Stanley Institutional Fund,  Inc., c/o  Chase Global Funds
Services Company, 73 Tremont Street, Boston, Massachusetts 02108-3913.
    
 
   
    "Good order"  means that  the  request to  redeem  shares must  include  the
following documentation:
    
 
   
         (a)  A letter of instruction or a stock assignment specifying the class
    and number  of  shares  or dollar  amount  to  be redeemed,  signed  by  all
    registered  owners  of the  shares  in the  exact  names in  which  they are
    registered;
    
 
   
        (b)  Any  required   signature  guarantees   (see  "Further   Redemption
    Information" below); and
    
 
   
         (c)  Other  supporting legal  documents, if  required,  in the  case of
    estates, trusts,  guardianships, custodianships,  corporations, pension  and
    profit sharing plans and other organizations.
    
 
   
    Shareholders who are uncertain of requirements for redemption should consult
with a Morgan Stanley Institutional Fund representative.
    
 
   
BY TELEPHONE
    
 
   
    Provided  you have previously elected the Telephone Redemption Option on the
Account Registration  Form, you  can  request a  redemption  of your  shares  by
calling  the Fund  and requesting  the redemption proceeds  be mailed  to you or
wired to your bank.  Please contact one of  Morgan Stanley Institutional  Fund's
representatives  for further details. In times of drastic market conditions, the
telephone redemption option  may be  difficult to implement.  If you  experience
difficulty in making a telephone redemption, your request may be made by mail or
overnight courier and will be implemented at the net asset value next determined
after  it is received. Redemption requests sent to the Fund through express mail
must be sent to Morgan Stanley Institutional Fund, Inc., c/o Chase Global  Funds
Services  Company, 73 Tremont Street, Boston,  Massachusetts 02108. The Fund and
the  Fund's  transfer  agent  (the  "Transfer  Agent")  will  employ  reasonable
procedures  to  confirm  that  the instructions  communicated  by  telephone are
genuine. These  procedures include  requiring the  investor to  provide  certain
personal  identification information at the time  an account is opened and prior
to effecting each transaction requested by telephone. In addition, all telephone
transaction requests will be recorded and  investors may be required to  provide
additional  telecopied  written  instructions  regarding  transaction  requests.
Neither the  Fund nor  the Transfer  Agent  will be  responsible for  any  loss,
liability, cost or expense for following instructions received by telephone that
either of them reasonably believes to be genuine.
    
 
                                       32
<PAGE>
    To  change the commercial  bank or account  designated to receive redemption
proceeds, a written  request must  be sent  to the  Fund at  the address  above.
Requests  to change the bank  or account must be  signed by each shareholder and
each signature must be guaranteed.
 
FURTHER REDEMPTION INFORMATION
 
    Normally the  Fund will  make payment  for all  shares redeemed  within  one
business  day of receipt  of the request, but  in no event  will payment be made
more than  seven days  after receipt  of  a redemption  request in  good  order.
However,  payments to investors  redeeming shares which  were purchased by check
will not be made until  payment for the purchase  has been collected, which  may
take up to eight days after the date of purchase. The Fund may suspend the right
of  redemption or postpone the date upon which redemptions are effected at times
when the NYSE is closed, or  under any emergency circumstances as determined  by
the Securities and Exchange Commission (the "Commission").
 
    If  the Board of  Directors determines that  it would be  detrimental to the
best interests of  the remaining  shareholders of  a Portfolio  to make  payment
wholly  or partly in cash, the Fund may  pay the redemption proceeds in whole or
in part by a distribution in-kind of securities held by the Portfolio in lieu of
cash   in    conformity   with    applicable    rules   of    the    Commission.
Distributions-in-kind  will be made in  readily marketable securities. Investors
may incur brokerage charges on the  sale of portfolio securities so received  in
payment of redemptions.
 
    To  protect  your account,  the Fund  and its  agents from  fraud, signature
guarantees are required for  certain redemptions to verify  the identity of  the
person  who has  authorized a redemption  from your account.  Please contact the
Fund for further  information. See "Redemption  of Shares" in  the Statement  of
Additional Information.
 
                              SHAREHOLDER SERVICES
 
   
EXCHANGE FEATURES
    
 
   
    You  may exchange shares that you own  in either Portfolio for shares of any
other available  portfolio of  the  Fund (other  than the  International  Equity
Portfolio,  which is  closed to  new investors). In  exchanging for  shares of a
portfolio with more  than one  class, the  class of  shares you  receive in  the
exchange  will be determined in the same  manner as any other purchase of shares
and will not  be based  on the  class of  shares surrendered  for the  exchange.
Consequently,  the same minimum initial investment  and minimum account size for
determining the  class  of shares  received  in  the exchange  will  apply.  See
"Purchase  of Shares."  Shares of  the portfolios  may be  exchanged by  mail or
telephone. The privilege to exchange shares  by telephone is automatic and  made
available  without shareholder election. Before you make an exchange, you should
read the prospectus of the portfolio(s) in which you seek to invest. Because  an
exchange  transaction  is treated  as a  redemption followed  by a  purchase, an
exchange would be considered  a taxable event for  shareholders subject to  tax.
The  exchange privilege  is only available  with respect to  portfolios that are
registered for  sale  in  a  shareholder's  state  of  residence.  The  exchange
privilege  may be modified or  terminated by the Fund  at any time upon 60-days'
notice to shareholders.
    
 
BY MAIL
 
   
    In order to  exchange shares  by mail, you  should include  in the  exchange
request  the name, class of shares and account number of your current portfolio,
the names of the portfolio(s) and class(es)  of shares into which you intend  to
exchange  shares, and the signatures of all registered account holders. Send the
exchange request  to Morgan  Stanley Institutional  Fund, Inc.,  P.O. Box  2798,
Boston, Massachusetts 02208-2798.
    
 
                                       33
<PAGE>
   
BY TELEPHONE
    
 
   
    When  exchanging shares by  telephone, have ready the  name, class of shares
and account number of  your current portfolio, the  name(s) of the  portfolio(s)
and  class(es) of shares into  which you intend to  exchange shares, your Social
Security number  or Tax  I.D. number,  and your  account address.  Requests  for
telephone  exchanges received prior to 4:00 p.m. (Eastern Time) are processed at
the close of business that same day based on the net asset value of the class of
each of  the portfolios  involved in  the exchange  of shares  at the  close  of
business.  Requests received  after 4:00 p.m.  (Eastern Time)  are processed the
next business  day based  on the  net asset  value determined  at the  close  of
business  on such day.  For additional information  regarding responsibility for
the authenticity of  telephoned instructions,  see "Redemption of  Shares --  By
Telephone" above.
    
 
   
TRANSFER OF REGISTRATION
    
 
   
    You  may transfer  the registration  of any of  your Fund  shares to another
person by writing  to Morgan  Stanley Institutional  Fund Inc.,  P.O. Box  2798,
Boston,  Massachusetts 02208-2798.  As in the  case of  redemptions, the written
request must  be  received  in good  order  before  any transfer  can  be  made.
Transferring  the  registration of  shares may  affect  the eligibility  of your
account for  a  given  class  of  each Portfolio's  shares  and  may  result  in
involuntary  conversion or redemption  of your shares.  See "Purchase of Shares"
above.
    
 
                              VALUATION OF SHARES
 
   
    The net asset  value per share  of a class  of shares of  the Portfolios  is
determined by dividing the total market value of the Portfolio's investments and
other  assets attributable to  such class, less  any liabilities attributable to
such class, by  the total  number of  outstanding shares  of such  class of  the
Portfolio.  Net  asset value  is  calculated separately  for  each class  of the
Portfolio. Net asset value per  share is determined as  of the regular close  of
the  NYSE on each day  that the NYSE is open  for business. Price information on
listed securities is  taken from the  exchange where the  security is  primarily
traded.  Securities  listed  on  a U.S.  securities  exchange  for  which market
quotations are available are valued at the last quoted sale price on the day the
valuation is made. Securities listed on  a foreign exchange are valued at  their
closing  price.  Unlisted securities  and listed  securities  not traded  on the
valuation date for which market quotations are not readily available are  valued
at  a price within a  range not exceeding the current  asked price nor less than
the current bid price. The current bid and asked prices are determined based  on
the bid and asked prices quoted on such valuation date by reputable brokers.
    
 
    Bonds and other fixed income securities are valued according to the broadest
and  most representative market,  which will ordinarily  be the over-the-counter
market. Net asset value includes interest  on fixed income securities, which  is
accrued  daily.  In addition,  bonds and  other fixed  income securities  may be
valued on the basis of prices provided by a pricing service when such prices are
believed to  reflect  the fair  market  value  of such  securities.  The  prices
provided  by a pricing service are determined without regard to bid or last sale
prices, but take into  account institutional size trading  in similar groups  of
securities  and any developments related  to the specific securities. Securities
not priced in this manner are valued  at the most recently quoted bid price,  or
when securities exchange valuations are used, at the latest quoted sale price on
the  day of valuation. If there is no  such reported sale, the latest quoted bid
price will be used. Securities purchased with remaining maturities of 60 days or
less are valued at amortized cost, if it approximates market value. In the event
that amortized  cost  does  not  approximate  market  value,  market  prices  as
determined above will be used.
 
                                       34
<PAGE>
    The value of other assets and securities for which no quotations are readily
available  (including  restricted  and unlisted  foreign  securities)  and those
securities for which it is inappropriate to determined prices in accordance with
the above-stated procedures, are  determined in good faith  at fair value  using
methods  determined by the  Board of Directors. For  purposes of calculating net
asset value per share, all assets and liabilities initially expressed in foreign
currencies will be translated into U.S. dollars at the mean of the bid price and
asked price of such currencies against the U.S. dollar last quoted by any  major
bank.
 
   
    Although  the legal rights of Class A  and Class B shares will be identical,
the different expenses borne  by each class will  result in different net  asset
values  and dividends for the class.  Dividends will differ by approximately the
amount of the distributions expense accrual differential among the classes.  The
net  asset value of  Class B shares will  generally be lower  than the net asset
value of the Class A shares as  a result of the distribution expense charged  to
Class B shares.
    
 
                            PERFORMANCE INFORMATION
 
   
    The  Fund may from time to time advertise the total return for each class of
the Portfolios.  THESE FIGURES  ARE BASED  ON HISTORICAL  EARNINGS AND  ARE  NOT
INTENDED  TO  INDICATE  FUTURE PERFORMANCE.  The  "total return"  shows  what an
investment in a class of the Portfolio would have earned over a specified period
of time (such as one,  five or ten years),  assuming that all distributions  and
dividends by the Portfolio were reinvested in the same class on the reinvestment
dates  during the period. Total return does not take into account any federal or
state income taxes that  may be payable on  dividends and distributions or  upon
redemption.  The Fund  may also  include comparative  performance information in
advertising or  marketing the  Portfolio's shares,  including data  from  Lipper
Analytical  Services, Inc.,  other industry  publications, business periodicals,
rating services and market indices.
    
 
   
    The performance figures  for Class  B shares  will generally  be lower  than
those  for Class  A shares because  of the  distribution fee charged  to Class B
shares.
    
 
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
 
   
    All income dividends and capital gains  distributions for a class of  shares
will automatically be reinvested in additional shares of such class at net asset
value,  except that,  upon written  notice to  the Fund  or by  checking off the
appropriate box in the Distribution  Option Section on the Account  Registration
Form,  a shareholder  may elect  to receive  income dividends  and capital gains
distributions in cash.
    
 
   
    Each Portfolio expects to distribute substantially all of its net investment
income in the form of annual dividends. Net realized gains of each Portfolio, if
any, after reduction  for any tax  loss carryforwards will  also be  distributed
annually.  Confirmations of the purchase of shares of each Portfolio through the
automatic reinvestment of income dividends and capital gains distributions  will
be  provided, pursuant  to Rule 10b-10(b)  under The Securities  Exchange Act of
1934, as amended, on the next  monthly client statement following such  purchase
of shares. Consequently, confirmations of such purchases will not be provided at
the  time of completion of such purchases as might otherwise be required by Rule
10b-10.
    
 
   
    Undistributed net  investment income  is included  in each  Portfolio's  net
assets  for the purpose of calculating net  asset value per share. Therefore, on
the "ex-dividend" date,  the net  asset value  per share  excludes the  dividend
(I.E.,  is reduced  by the  per share  amount of  the dividend).  Dividends paid
shortly after the purchase of shares by an investor, although in effect a return
of capital, are taxable to shareholders subject to income tax.
    
 
                                       35
<PAGE>
   
    Because of  the  distribution  fee  and  any  other  expenses  that  may  be
attributable  to the  Class B  shares, the  net income  attributable to  and the
dividends payable  on  Class  B  shares  will  be  lower  than  the  net  income
attributable  to and the dividends  payable on Class A  shares. As a result, the
net asset value per share of the classes of each Portfolio will differ at times.
Expenses of each  Portfolio allocated to  a particular class  of shares  thereof
will be borne on a pro rata basis by each outstanding share of that class.
    
 
                                     TAXES
 
   
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
    
 
   
    No  attempt has been made to present  a detailed explanation of the federal,
state, or  local  income tax  treatment  of  a Portfolio  or  its  shareholders.
Accordingly,  shareholders  are urged  to consult  their tax  advisors regarding
specific questions as to federal, state and local income taxes.
    
 
   
    Each Portfolio  is treated  as  a separate  entity  for federal  income  tax
purposes  and is not  combined with the Fund's  other portfolios. Each Portfolio
intends to qualify for the  special tax treatment afforded regulated  investment
companies  under Subchapter M of  the Internal Revenue Code  of 1986, as amended
(the "Code"), so that the  Portfolio will be relieved  of federal income tax  on
that  part of its net investment income and net capital gain that is distributed
to shareholders.
    
 
   
    Each Portfolio distributes  substantially all of  its net investment  income
(including,  for  this purpose,  net short-term  capital gain)  to shareholders.
Dividends from a Portfolio's net  investment income are taxable to  shareholders
as  ordinary  income, whether  received in  cash or  in additional  shares. Such
dividends  paid   by  a   Portfolio   generally  will   qualify  for   the   70%
dividends-received  deduction  for corporate  shareholders. Each  Portfolio will
report annually to its shareholders the amount of dividend income qualifying for
such treatment.
    
 
   
    Distributions of net capital gain (the excess of net long-term capital  gain
over  net  short-term capital  loss) are  taxable  to shareholders  as long-term
capital gain, regardless of how long  shareholders have held their shares.  Each
Portfolio  sends  reports annually  to shareholders  of  the federal  income tax
status of all distributions made during the preceding year.
    
 
   
    Each  Portfolio  intends   to  make  sufficient   distributions  or   deemed
distributions  of its ordinary income and capital gain net income (the excess of
short-term and long-term  capital gains  over short-term  and long-term  capital
losses), including any available capital loss carryforwards, prior to the end of
each calendar year to avoid liability for federal excise tax.
    
 
   
    Dividends  and  other  distributions  declared by  a  Portfolio  in October,
November or December of any year and payable to shareholders of record on a date
in such month will be deemed to have been paid by the Portfolio and received  by
the  shareholders on December 31  of that year if  the distributions are paid by
the Portfolio at any time during the following January.
    
 
   
    The sale, exchange  or redemption of  shares may result  in taxable gain  or
loss to the selling, exchanging or redeeming shareholder, depending upon whether
the  fair market value  of the redemption  proceeds exceeds or  is less than the
Shareholder's adjusted  basis in  the  sold, exchanged  or redeemed  shares.  If
capital  gain distributions have been made with  respect to shares that are sold
at a loss after being held for six months or less, then the loss is treated as a
long-term capital loss to the extent of the capital gain distributions.
    
 
                                       36
<PAGE>
    The conversion of Class A shares to  Class B shares should not be a  taxable
event to the shareholder.
 
    Shareholders  are urged  to consult with  their tax  advisors concerning the
application of state and local income taxes to investments in a Portfolio, which
may differ from the federal income tax consequences described above.
 
    Investment income  received  by  a Portfolio  from  sources  within  foreign
countries  may be subject to foreign income taxes withheld at the source. To the
extent that a  Portfolio is liable  for foreign income  taxes so withheld,  each
Portfolio  intends to operate so as to meet the requirements of the Code to pass
through to the shareholders credit for foreign income taxes paid. Although  each
Portfolio  intends to  meet Code  requirements to  pass through  credit for such
taxes, there can be no assurance that each Portfolio will be able to do so.
 
    THE  TAX  DISCUSSION  SET  FORTH  ABOVE  IS  INCLUDED  HEREIN  FOR   GENERAL
INFORMATION  ONLY. PROSPECTIVE INVESTORS  SHOULD CONSULT THEIR  OWN TAX ADVISERS
WITH RESPECT TO THE TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN THE PORTFOLIO.
 
                             PORTFOLIO TRANSACTIONS
 
    The Investment  Advisory  Agreement authorizes  the  Adviser to  select  the
brokers  or  dealers that  will execute  the purchases  and sales  of investment
securities for the Portfolios and directs the Adviser to use its best efforts to
obtain the best available price and most favorable execution with respect to all
transactions for the  Portfolios. The  Fund has  authorized the  Adviser to  pay
higher commissions in recognition of brokerage services which, in the opinion of
the Adviser, are necessary for the achievement of better execution, provided the
Adviser believes this to be in the best interest of the Fund.
 
    Since shares of the Portfolios are not marketed through intermediary brokers
or  dealers, it is  not the Fund's  practice to allocate  brokerage or principal
business on the basis of sales of  shares which may be made through such  firms.
However,  the Adviser may  place portfolio orders  with qualified broker-dealers
who recommend the  Fund's portfolios or  who act  as agents in  the purchase  of
shares of the Fund's portfolios for their clients.
 
    In  purchasing and selling  securities for the Portfolios,  it is the Fund's
policy to seek to obtain quality execution at the most favorable prices, through
responsible  broker-dealers.  In   selecting  broker-dealers   to  execute   the
securities  transactions for the Portfolios, consideration will be given to such
factors as the price of the security,  the rate of the commission, the size  and
difficulty  of  the  order,  the  reliability,  integrity,  financial condition,
general execution and operational capabilities of competing broker-dealers,  and
the  brokerage  and  research services  which  they  provide to  the  Fund. Some
securities considered for investment by  the Portfolios may also be  appropriate
for  other clients  served by  the Adviser.  If purchase  or sale  of securities
consistent with the  investment policies  of the Portfolio  and one  or more  of
these  other clients served  by the Adviser  is considered at  or about the same
time, transactions in such securities will be allocated among the Portfolios and
such other  clients in  a manner  deemed  fair and  reasonable by  the  Adviser.
Although  there is  no specified formula  for allocating  such transactions, the
various allocation  methods  used  by  the Adviser,  and  the  results  of  such
allocations, are subject to periodic review by the Fund's Board of Directors.
 
    Subject to the overriding objective of obtaining the best possible execution
of  orders,  the  Adviser may  allocate  a  portion of  the  Portfolio brokerage
transactions   to   Morgan    Stanley   or   broker    affiliates   of    Morgan
 
                                       37
<PAGE>
Stanley.  In order for Morgan Stanley or  its affiliates to effect any portfolio
transactions for the Fund, the commissions, fees or other remuneration  received
by Morgan Stanley or such affiliates must be reasonable and fair compared to the
commissions, fees or other remuneration paid to other brokers in connection with
comparable  transactions involving similar securities being purchased or sold on
a securities exchange during a comparable period of time. Furthermore, the Board
of Directors of the Fund,  including a majority of  those Directors who are  not
"interested  persons," as  defined in  the Investment  Company Act  of 1940 (the
"1940 Act") have  adopted procedures  which are reasonably  designed to  provide
that  any commissions, fees or other remuneration paid to Morgan Stanley or such
affiliates are consistent with the foregoing standard.
 
    Portfolio securities will not  be purchased from or  through, or sold to  or
through,  the Adviser or Morgan Stanley  or any "affiliated persons," as defined
in the 1940 Act, of Morgan Stanley when such entities are acting as  principals,
except to the extent permitted by law.
 
   
    Although  neither  Portfolio will  invest  for short-term  trading purposes,
investment securities may be sold from time to time without regard to the length
of time they have  been held. The Emerging  Markets Portfolio anticipates  that,
under  normal circumstances, its annual portfolio  turnover rate will not exceed
50%.  The  Emerging  Markets  Debt  Portfolio  anticipates  that,  under  normal
circumstances,  its annual  portfolio turnover rate  will not  exceed 100%. High
portfolio turnover involves correspondingly greater transaction costs which will
be borne  directly by  the  respective Portfolio.  In addition,  high  portfolio
turnover  may  result  in more  capital  gains  which would  be  taxable  to the
shareholders of the  respective Portfolio.  The tables set  forth in  "Financial
Highlights" present the Portfolio's historical turnover rates.
    
 
                              GENERAL INFORMATION
 
DESCRIPTION OF COMMON STOCK
 
   
    The  Fund was  organized as  a Maryland  corporation on  June 16,  1988. The
Articles of Incorporation, as amended and restated, permit the Fund to issue  up
to  34 billion shares of common stock,  with $.001 par value per share. Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number of shares the  Fund is authorized  to issue without  the approval of  the
shareholders  of the  Fund. Subject  to the  notice period  to shareholders with
respect to shares held by the shareholders, the Board of Directors has the power
to designate one or more classes of  shares of common stock and to classify  and
reclassify  any  unissued shares  with respect  to such  classes. The  shares of
common stock of each  portfolio are currently classified  into two classes,  the
Class  A shares and the Class B  shares, except for the International Small Cap,
Money Market and  Municipal Money Market  Portfolios, which only  offer Class  A
shares.
    
 
   
    The   shares  of   the  Portfolios,  when   issued,  will   be  fully  paid,
nonassessable, fully transferable and  redeemable at the  option of the  holder.
The  shares have no preference as to conversion, exchange, dividends, retirement
or other features and have no  pre-emptive rights. The shares of each  Portfolio
have non-cumulative voting rights, which means that the holders of more than 50%
of  the  shares voting  for  the election  of Directors  can  elect 100%  of the
Directors if they choose to do so.  Persons or organizations owning 25% or  more
of  the outstanding shares of a Portfolio  may be presumed to "control" (as that
term is defined in the 1940 Act) that Portfolio. Under Maryland law, the Fund is
not required to hold an annual meeting of its shareholders unless required to do
so under the 1940 Act.
    
 
                                       38
<PAGE>
REPORTS TO SHAREHOLDERS
 
    The Fund will send to its  shareholders annual and semi-annual reports;  the
financial  statements  appearing in  annual reports  are audited  by independent
accountants. Monthly unaudited portfolio  data is also  available from the  Fund
upon request.
 
    In addition, the Adviser, or its agent, as Transfer Agent, will send to each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
 
CUSTODIAN
 
    As  of September 1,  1995, domestic securities  and cash are  held by Chase,
which replaced U.S.  Trust as  the Fund's domestic  custodian. Chase  is not  an
affiliate  of  the Adviser  or the  Distributor.  Morgan Stanley  Trust Company,
Brooklyn, New York ("MSTC"),  an affiliate of the  Adviser and the  Distributor,
acts  as the Fund's custodian for foreign  assets held outside the United States
and employs subcustodians  approved by  the Board of  Directors of  the Fund  in
accordance  with regulations of  the Securities and  Exchange Commission for the
purpose of providing  custodial services  for such  assets. MSTC  may also  hold
certain  domestic assets for  the Fund. For more  information on the custodians,
see "General Information -- Custody Arrangements" in the Statement of Additional
Information.
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
    Chase  Global   Funds  Services   Company,   73  Tremont   Street,   Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
 
INDEPENDENT ACCOUNTANTS
 
    Price  Waterhouse LLP  serves as  independent accountants  for the  Fund and
audits its annual financial statements.
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       39
<PAGE>
<TABLE>
<CAPTION>

   MORGAN STANLEY INSTITUTIONAL FUND, INC.
          EMERGING MARKETS AND EMERGING MARKETS DEBT PORTFOLIOS
          P.O. BOX 2798, BOSTON, MA 02208-2798


- ---------------------------------------------------------------------------------------------------------------

                           ACCOUNT REGISTRATION FORM
- ---------------------------------------------------------------------------------------------------------------
<S>                        <C>
ACCOUNT INFORMATION        If you need assistance in filling out this form     
Fill in where applicable   for the Morgan Stanley Institutional Fund, please   
                           contact your Morgan Stanley representative or call  
                           us toll free 1-(800)-548-7786. Please print all     
                           items except signature, and mail to the Fund at the
                           address above.

- ---------------------------------------------------------------------------------------------------------------
A)  REGISTRATION
    1. INDIVIDUAL            1. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
                                 First Name           Initial              Last Name
    2. JOINT TENANTS         2. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       (RIGHTS OF                First Name           Initial              Last Name
       SURVIVORSHIP            / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       PRESUMED UNLESS           First Name           Initial              Last Name
       TENANCY IN COMMON 
       IS INDICATED)      
- ---------------------------------------------------------------------------------------------------------------
    3. CORPORATIONS,        3.  / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       TRUSTS AND OTHERS       
       Please call the          / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       Fund for additional
       documents that may       / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       be required to set 
       up account and to 
       authorize transactions.
                                Type of / / INCORPORATED / / UNINCORPORATED / / PARTNERSHIP / / UNIFORM GIFT/TRANSFER TO MINOR 
                                Registration:                 ASSOCIATION                   (ONLY ONE CUSTODIAN AND MINOR PERMITTED)


                                / / TRUST __________________________________     / / OTHER (Specify) ______________________________
- ---------------------------------------------------------------------------------------------------------------
B)  MAILING ADDRESS         Street or P.O. Box / / / / / / / / / / / / / / / / / / / / / / / / / / / /

    Please fill in 
    completely, including   City / / / / / / / / / / / / / State / / / Zip / / / / / /-/ / / / / / / / 
    telephone number(s).
                            Home                                   Business
                            Telephone No./ / / /-/ / / /-/ / / / / Telephone No./ / / /-/ / / /-/ / / /
                            / / United States  / / Resident  / /Non-Resident Alien:
                                Citizen            Alien        Indicate Country of Residence _________
- ---------------------------------------------------------------------------------------------------------------
C)  TAXPAYER                PART 1. Enter your Taxpayer         C) IMPORTANT TAX INFORMATION 
    IDENTIFICATION          Identification Number. For most          You (as a payee) are required by
    NUMBER                  individual taxpayers, this is your     law to provide us (as payer) with
    If the account is in    Social Security Number.                your correct Taxpayer Identification
    more than one name,     TAXPAYER IDENTIFICATION NUMBER         Number. Accounts that have a missing
    CIRCLE THE NAME OF THE    / / / /-/ / / / / / / / /            or incorrect Taxpayer Identification
    PERSON WHOSE TAXPAYER               OR                         Number will be subject to backup
    IDENTIFICATION NUMBER       SOCIAL SECURITY NUMBER             withholding at a 31% rate on dividends,
    IS PROVIDED IN SECTION    / / / /-/ / /-/ / / / /              distributions and other payments.
    A) ABOVE. If no name      PART 2. BACKUP WITHHOLDING           If you have not provided us with
    is circled, the number    / / Check this box if you are        your correct taxpayer identification
    will be considered to be  NOT subject to Backup                number, you may be subject to 
    that of the last name     Withholding under the                a $50 penalty imposed by the Internal
    listed. For Custodian     provisions of Section                Revenue Service.
    account of a minor        3406(a)(1)(C) of the Internal          Backup withholding is not an
    (Uniform Gift/Transfer    Revenue Code.                        additional tax; the tax liability of
    to Minor Act), give the                                        persons subject to backup withholding
    Social Security Number                                         will be reduced by the amount of tax
    of the minor.                                                  withheld. If withholding results in
                                                                   an overpayment of taxes, a refund 
                                                                   may be obtained. You may be notified
                                                                   that you are subject to backup 
                                                                   withholding under Section 3406(a)(1)(C)
                                                                   of the Internal Revenue Code because you
                                                                   have underreported interest or dividends
                                                                   or you were required to but failed to
                                                                   file a return which would have included a
                                                                   reportable interest or dividend payment. IF
                                                                   YOU HAVE NOT BEEN SO NOTIFIED, CHECK THE
                                                                   BOX IN PART 2 AT LEFT.

- ---------------------------------------------------------------------------------------------------------------

D)  PORTFOLIO AND          For Purchase of the following Portfolio(s):     
    CLASS SELECTION        Emerging Markets Portfolio                  / / Class A Shares $____ / / Class B Shares $____
    (Class A shares        Emerging Markets Debt Portfolio             / / Class A Shares $____ / / Class B Shares $____
    minimum $500,000 
    for each Portfolio                                                      Total Initial Investment $_____________
    and Class B shares
    minimum $100,000 for
    each Portfolio).
    Please indicate
    Portfolio, class and
    amount.

- ---------------------------------------------------------------------------------------------------------------

E)  METHOD OF   Payment by:
    INVESTMENT  / / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND, INC.--SMALL CAP VALUE EQUITY, VALUE EQUITY
    Please          AND BALANCED PORTFOLIOS)
    indicate
    manner of   / / Exchange $____________ From________________ / / / / / / / / / / /-/ /
    payment.                                Name of Portfolio          Account No.

               / / Account previously established by: / / Phone exchange / / Wire on_____/ / / / / / / / / / / /-/ /
                                                                                    Date         Account No.   (Check
                                                                              (Previously assigned by the Fund) Digit)


 
<PAGE>

- ---------------------------------------------------------------------------------------------------------------

F)  DISTRIBUTION                                       Income dividends and capital gains distributions (if any) will
    OPTION                                             be reinvested in additional shares unless either box below is
                                                       checked.

                                                       / / Income dividends to be paid in cash, capital
                                                           gains distributions (if any) in shares.

                                                      / /  Income dividends and capital gains distributions
                                                           (if any) to be paid in cash.

- ---------------------------------------------------------------------------------------------------------------


G)  TELEPHONE                    / / I/we hereby authorize the Fund and its      ______________________   ________________
    REDEMPTION                       agents to honor any telephone requests      Name of COMMERCIAL Bank  Bank Account No.
    Please select at time of         to wire redemption proceeds to the            (Not Savings Bank)
    initial application if you       commercial bank indicated at rightand/or 
    wish to redeem shares by         mail redemption proceeds to the name and                             ________________
    telephone. A SIGNATURE           address in which my/our fund account is                                 Bank ABA No.
    GUARANTEE IS REQUIRED IF         registered if such requests are believed 
    BANK ACCOUNT IS NOT              to be authentic.                           _________________________________________________
    REGISTERED IDENTICALLY TO    The Fund and the Fund's Transfer Agent will    Name(s) in which your BANK Account is Established
    YOUR FUND ACCOUNT.           employ reasonable procedures to confirm that
                                 instructions communicated by telephone are     _________________________________________________
    TELEPHONE REQUESTS FOR       genuine. These procedures include requiring                 Bank's Street Address
    REDEMPTIONS WILL NOT BE      the investor to provide certain personal
    HONORED UNLESS THE BOX IS    identification information at the time an      _________________________________________________
    CHECKED.                     account is opened and prior to effecting each  City                    State                Zip
                                 transaction requested by telephone. In addition,
                                 all telephone transaction requests will be recorded
                                 and investors may be required to provide additional
                                 telecopied written instructions of transaction
                                 requests. Neither the Fund nor the Transfer Agent will
                                 be responsible for any loss, liability, cost or expense
                                 for following instructions received by telephone that
                                 it reasonably believes to be genuine.


- ---------------------------------------------------------------------------------------------------------------

H)  INTERESTED PARTY
    OPTION
    In addition to the account   _________________________________________________________________
    statement sent to my/our                                 Name
    registered address, I/we     _________________________________________________________________
    hereby authorize the fund    
    to mail duplicate            _________________________________________________________________
    statements to the name and                              Address
    address provided at right.
                                 _________________________________________________________________
                                  City                      State                     Zip Code

- ---------------------------------------------------------------------------------------------------------------

I)  DEALER 
    INFORMATION                  _______________________  _______________________________  ___________
                                 Representative Name          Representative No.             Branch No.

- ---------------------------------------------------------------------------------------------------------------

J)  SIGNATURE OF        The undersigned certify(ies)  that I/we  have full  authority and  legal
    ALL HOLDERS         capacity  to purchase and redeem shares of the Fund and affirm that I/we
    AND TAXPAYER        have received a current Prospectus  of the Morgan Stanley  Institutional
    CERTIFICATION       Fund,  Inc. and agree to  be bound by its  terms. UNDER THE PENALTIES OF
    Sign Here >         PERJURY, I/WE CERTIFY THAT THE INFORMATION PROVIDED IN SECTION C)
                        ABOVE IS TRUE, CORRECT AND COMPLETE.

                        (X)                                 (X)
                        __________________________________  ______________________________________
                        Signature                Date       Signature                  Date


- ---------------------------------------------------------------------------------------------------------------


</TABLE>


<PAGE>
                 (This page has been left blank intentionally.)
<PAGE>
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
 
  NO  DEALER, SALES  REPRESENTATIVE OR ANY  OTHER PERSON HAS  BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE  CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS  HAVING BEEN AUTHORIZED BY THE FUND  OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF  THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION  TO
ANY  PERSON TO WHOM  IT IS UNLAWFUL TO  MAKE SUCH OFFER  OR SOLICITATION IN SUCH
JURISDICTION.
 
                           --------------------------
 
                               TABLE OF CONTENTS
 
   
<TABLE>
<S>                                                 <C>
                                                    PAGE
                                                    ----
Fund Expenses.....................................    2
Financial Highlights..............................    4
Prospectus Summary................................    7
Investment Objectives and Policies................   11
Additional Investment Information.................   15
Investment Limitations............................   24
Management of the Fund............................   25
Purchase of Shares................................   27
Redemption of Shares..............................   31
Shareholder Services..............................   33
Valuation of Shares...............................   34
Performance Information...........................   35
Dividends and Capital Gains Distributions.........   35
Taxes.............................................   36
Portfolio Transactions............................   37
General Information...............................   38
Account Registration Form
</TABLE>
    
 
                           EMERGING MARKETS PORTFOLIO
                        EMERGING MARKETS DEBT PORTFOLIO
 
                               PORTFOLIOS OF THE
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
 
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
 
- ---------------------------------
- ---------------------------------
- ---------------------------------
- ---------------------------------
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
   -------------------------------------------------------------------------
 
                            EQUITY GROWTH PORTFOLIO
                           EMERGING GROWTH PORTFOLIO
                               MICROCAP PORTFOLIO
                          AGGRESSIVE EQUITY PORTFOLIO
 
                               PORTFOLIOS OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
 
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
                                ----------------
 
   
    Morgan  Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company, or mutual fund, which offers redeemable shares in
a   series   of   diversified   and   non-diversified   investment    portfolios
("portfolios").   The  Fund   currently  consists   of  twenty-eight  portfolios
representing a  broad range  of  investment choices.  The  Fund is  designed  to
provide clients with attractive alternatives for meeting their investment needs.
This  prospectus (the  "Prospectus") pertains  to the  Class A  and the  Class B
shares of the  Equity Growth,  Emerging Growth, MicroCap  and Aggressive  Equity
Portfolios (the "Portfolios"). On January 2, 1996, the Portfolios began offering
two classes of shares, the Class A shares and the Class B shares, except for the
Money  Market,  Municipal Money  Market and  International Small  Cap Portfolios
which only offer Class  A Shares. All  shares of the  Portfolios owned prior  to
January 2, 1996 were redesignated Class A shares on January 2, 1996. The Class A
and  Class B shares  currently offered by the  Portfolios have different minimum
investment requirements and fund expenses. Shares of the portfolios are  offered
with  no sales charge or  exchange or redemption fee  (with the exception of the
International Small Cap Portfolio).
    
 
    The  EQUITY  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation   by
investing  primarily in  growth-oriented equity  securities of  medium and large
capitalization corporations.
 
    The EMERGING  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation  by
investing  primarily  in  growth-oriented equity  securities  of small-to-medium
sized corporations.
 
    The MICROCAP  PORTFOLIO seeks  long-term capital  appreciation by  investing
primarily in growth-oriented equity securities of small corporations.
 
    The  AGGRESSIVE EQUITY PORTFOLIO  is a non-diversified  portfolio that seeks
long-term capital appreciation  by investing primarily  in corporate equity  and
equity-linked securities.
 
    INVESTORS  SHOULD NOTE THAT EACH OF  THE EQUITY GROWTH AND AGGRESSIVE EQUITY
PORTFOLIOS MAY INVEST UP  TO 10% OF ITS  TOTAL ASSETS IN RESTRICTED  SECURITIES.
INVESTMENTS  IN RESTRICTED  SECURITIES IN  EXCESS OF  5% OF  A PORTFOLIO'S TOTAL
ASSETS MAY BE CONSIDERED  A SPECULATIVE ACTIVITY, MAY  INVOLVE GREATER RISK  AND
MAY INCREASE THE PORTFOLIO'S EXPENSES.
 
    The  Fund is designed  to meet the investment  needs of discerning investors
who place a premium on quality  and personal service. With Morgan Stanley  Asset
Management   Inc.  as   Adviser  and   Administrator  (the   "Adviser"  and  the
"Administrator"), and with Morgan Stanley & Co. Incorporated ("Morgan  Stanley")
as Distributor, the Fund makes available to institutional investors and high net
worth  individual  investors  a  series of  portfolios  which  benefit  from the
investment expertise and commitment to excellence associated with Morgan Stanley
and its affiliates.
 
   
    This Prospectus is designed to set forth concisely the information about the
Fund that a prospective investor should  know before investing and it should  be
retained  for future reference. The Fund  offers additional portfolios which are
described in other prospectuses and  under "Prospectus Summary" below. The  Fund
currently  offers the following portfolios:  (i) GLOBAL AND INTERNATIONAL EQUITY
- -- Active Country Allocation, Asian  Equity, Emerging Markets, European  Equity,
Global  Equity, Gold, International  Equity, International Magnum, International
Small Cap, Japanese Equity  and Latin American Portfolios;  (ii) U.S. EQUITY  --
Aggressive  Equity, Emerging  Growth, Equity  Growth, MicroCap,  Small Cap Value
Equity, Value Equity  and U.S. Real  Estate Portfolios; (iii)  EQUITY AND  FIXED
INCOME  -- Balanced Portfolio; (iv) FIXED INCOME -- Emerging Markets Debt, Fixed
Income,  Global  Fixed  Income,  High  Yield,  Mortgage-Backed  Securities   and
Municipal  Bond Portfolios; and  (v) MONEY MARKET --  Money Market and Municipal
Money Market Portfolios. Additional information about the Fund is contained in a
"Statement of Additional Information" dated  May 1, 1996, which is  incorporated
herein   by  reference.  The   Statement  of  Additional   Information  and  the
prospectuses pertaining to the other portfolios  of the Fund are available  upon
request  and without charge  by writing or  calling the Fund  at the address and
telephone number set forth above.
    
 
  THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES AND
     EXCHANGE COMMISSION OR  ANY STATE SECURITIES  COMMISSION, NOR HAS  THE
     SECURITIES   AND  EXCHANGE   COMMISSION  OR   ANY  STATE  SECURITIES
       COMMISSION  PASSED  UPON  THE   ACCURACY  OR  ADEQUACY  OF   THIS
        PROSPECTUS. ANY REPRESENTATION TO THE
                                   CONTRARY IS A CRIMINAL OFFENSE.
 
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1996.
<PAGE>
                                 FUND EXPENSES
 
    The  following table illustrates the expenses and fees that a shareholder of
the Portfolios indicated below will incur:
 
<TABLE>
<CAPTION>
                                                           EQUITY      EMERGING                 AGGRESSIVE
                                                           GROWTH       GROWTH      MICROCAP      EQUITY
SHAREHOLDER TRANSACTION EXPENSES                          PORTFOLIO    PORTFOLIO    PORTFOLIO    PORTFOLIO
- -------------------------------------------------------  -----------  -----------  -----------  -----------
<S>                                                      <C>          <C>          <C>          <C>
Maximum Sales Load Imposed on Purchases
  Class A..............................................        None         None         None         None
  Class B..............................................        None         None         None         None
Maximum Sales Load Imposed on Reinvested Dividends
  Class A..............................................        None         None         None         None
  Class B..............................................        None         None         None         None
Deferred Sales Load
  Class A..............................................        None         None         None         None
  Class B..............................................        None         None         None         None
Redemption Fees
  Class A..............................................        None         None         None         None
  Class B..............................................        None         None         None         None
Exchange Fees
  Class A..............................................        None         None         None         None
  Class B..............................................        None         None         None         None
</TABLE>
 
   
<TABLE>
<CAPTION>
                                                           EQUITY      EMERGING                 AGGRESSIVE
                                                           GROWTH       GROWTH      MICROCAP      EQUITY
ANNUAL FUND OPERATING EXPENSES                            PORTFOLIO    PORTFOLIO    PORTFOLIO    PORTFOLIO
- -------------------------------------------------------  -----------  -----------  -----------  -----------
<S>                                                      <C>          <C>          <C>          <C>
 (AS A PERCENTAGE OF AVERAGE NET ASSETS)
Management Fee (Net of Fee Waivers)*
  Class A..............................................       0.52%        0.99%        1.05%+       0.21%
  Class B..............................................       0.52%        0.99%        1.05%+       0.21%
12b-1 Fees
  Class A..............................................        None         None         None         None
  Class B..............................................       0.25%        0.25%        0.25%+       0.25%
Other Expenses
  Class A..............................................       0.28%        0.26%        0.45%+       0.79%
  Class B..............................................       0.28%        0.26%        0.45%+       0.79%
                                                         -----------  -----------  -----------  -----------
Total Operating Expenses (Net of Fee Waivers)*
  Class A..............................................       0.80%        1.25%        1.50%+       1.00%
  Class B..............................................       1.05%        1.50%        1.75%+       1.25%
                                                         -----------  -----------  -----------  -----------
                                                         -----------  -----------  -----------  -----------
</TABLE>
    
 
- ------------------------
   
*The Adviser  has agreed  to waive  its management  fees and/or  reimburse  each
 Portfolio,  if necessary,  if such  fees would  cause any  of the  total annual
 operating expenses of the Portfolios to exceed a specified percentage of  their
 respective  average daily net assets. Set  forth below, for each Portfolio, are
 the management fees and total operating expenses absent such fee waivers and/or
 expense reimbursements as a percent of average daily net assets of the Class  A
 shares and Class B shares, respectively, of each Portfolio.
    
 
                                       2
<PAGE>
 
   
<TABLE>
<CAPTION>
                                                                                           TOTAL OPERATING
                                                                                         EXPENSES ABSENT FEE
                                                                                               WAIVERS
                                                              MANAGEMENT FEES ABSENT    ----------------------
PORTFOLIO                                                           FEE WAIVERS          CLASS A    CLASS B+
- -----------------------------------------------------------  -------------------------  ---------  -----------
<S>                                                          <C>                        <C>        <C>
Equity Growth..............................................              0.60%              0.88%       1.13%
Emerging Growth............................................              1.00%              1.26%       1.51%
MicroCap...................................................              1.25%              1.50%+      1.75%
Aggressive Equity..........................................              0.80%              1.59%       1.84%
</TABLE>
    
 
- ------------------------------
+  Estimated.
 
These  reductions became or  will become effective  as of the  inception of each
Portfolio. As a result of these reductions, the Management Fees stated above are
lower than  the contractual  fees stated  under "Management  of the  Fund."  For
further information on Fund expenses, see "Management of the Fund."
 
   
    The  purpose of the table  above is to assist  the investor in understanding
the various expenses that  an investor in the  Portfolios will bear directly  or
indirectly.  The Class A  expenses and fees  for the Equity  Growth and Emerging
Growth Portfolios are based on actual figures for the fiscal year ended December
31, 1995. The Class A expenses and fees for the MicroCap Portfolio are based  on
estimates,  assuming that the average daily net  assets of the Class A shares of
the MicroCap Portfolio will  be $50,000,000. The Class  B expenses and fees  for
each  Portfolio  are based  on estimates,  assuming that  the average  daily net
assets of  the Class  B shares  of each  Portfolio will  be $50,000,000.  "Other
Expenses"  include  Board  of  Directors'  fees  and  expenses,  amortization of
organizational costs, filing fees, professional  fees and costs for  shareholder
reports.  Due to  the continuous nature  of Rule  12b-1 fees, long  term Class B
shareholders may pay more than the  equivalent of the maximum front-end  charges
otherwise permitted by the Rules of Fair Practice of the National Association of
Securities Dealers, Inc. ("NASD").
    
 
                                       3
<PAGE>
    The  following  example illustrates  the expenses  that you  would pay  on a
$1,000 investment assuming (1) a 5% annual rate of return and (2) redemption  at
the  end of each time period. As noted in the table above, the Portfolios charge
no redemption fees of any kind. The example is based on total operating expenses
of the Portfolios after fee waivers.
 
   
<TABLE>
<CAPTION>
                                                                       1 YEAR       3 YEARS      5 YEARS     10 YEARS
                                                                     -----------  -----------  -----------  -----------
<S>                                                                  <C>          <C>          <C>          <C>
Equity Growth Portfolio
  Class A..........................................................   $       8    $      26    $      44    $      99
  Class B..........................................................          11           33           58          128
Emerging Growth Portfolio
  Class A..........................................................          13           40           69          151
  Class B..........................................................          15           47           82          179
MicroCap Portfolio
  Class A..........................................................          15           47        *            *
  Class B..........................................................          18           55        *            *
Aggressive Equity Portfolio
  Class A..........................................................          10           32           55          122
  Class B..........................................................          13           40           69          151
</TABLE>
    
 
- ------------------------------
   
*  Because the MicroCap Portfolio has not yet commenced operations the Fund  has
   not projected expenses beyond the 3-year period shown for the Portfolio.
    
 
    THIS  EXAMPLE SHOULD  NOT BE CONSIDERED  A REPRESENTATION OF  PAST OR FUTURE
EXPENSES OR  PERFORMANCE. ACTUAL  EXPENSES MAY  BE GREATER  OR LESS  THAN  THOSE
SHOWN.
 
    The  Fund intends  to comply  with all  state laws  that restrict investment
company expenses. Currently, the  most restrictive state  law requires that  the
aggregate  annual expenses  of an  investment company  shall not  exceed two and
one-half percent (2 1/2%) of  the first $30 million  of average net assets,  two
percent (2%) of the next $70 million of average net assets, and one and one-half
percent (1 1/2%) of the remaining net assets of such investment company.
 
    The  Adviser has agreed to a reduction in  the amounts payable to it, and to
reimburse the Portfolios, if  necessary, if in  any fiscal year  the sum of  the
Portfolios' expenses exceeds the limit set by applicable state law.
 
                                       4
<PAGE>
                              FINANCIAL HIGHLIGHTS
 
   
    The  following table provides financial highlights for the Class A shares of
the Equity Growth, Emerging Growth and Aggressive Equity Portfolios for each  of
the  periods presented. The audited financial  highlights for the Class A shares
for the fiscal year  ended December 31,  1995 are part  of the Fund's  financial
statements  which  appear  in the  Fund's  December  31, 1995  Annual  Report to
Shareholders and  which  are included  in  the Fund's  Statement  of  Additional
Information. The Portfolios' financial highlights for each of the periods in the
five  years ended December 31,  1995 have been audited  by Price Waterhouse LLP,
whose unqualified report thereon is also included in the Statement of Additional
Information. Additional  performance  information  for the  Class  A  shares  is
included  in the Annual  Report. The Annual Report  and the financial statements
therein, along with the Statement of Additional Information, are available at no
cost from the Fund at the address  and telephone number noted on the cover  page
of  this Prospectus.  Financial highlights  are not  available for  the MicroCap
Portfolio nor for  the new  Class B  shares since they  were not  offered as  of
December  31, 1995. Subsequent to October 31, 1992 (the Fund's prior fiscal year
end), the  Fund  changed its  fiscal  year end  to  December 31.  The  following
information  should be  read in  conjunction with  the financial  statements and
notes thereto.
    
 
                                       5
<PAGE>
                            EQUITY GROWTH PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                       APRIL 2,                  TWO MONTHS
                                       1991* TO    YEAR ENDED       ENDED       YEAR ENDED     YEAR ENDED     YEAR ENDED
                                      OCTOBER 31,  OCTOBER 31,  DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,
                                         1991         1992          1992           1993           1994           1995
                                      -----------  -----------  -------------  -------------  -------------  -------------
<S>                                   <C>          <C>          <C>            <C>            <C>            <C>
NET ASSET VALUE, BEGINNING OF
 PERIOD.............................   $   10.00    $   10.66     $   11.44      $   11.88      $   12.14      $   12.02
                                      -----------  -----------  -------------  -------------  -------------  -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1).........        0.05         0.16          0.03           0.22           0.17           0.22
  Net Realized and Unrealized Gain
   on Investments...................        0.61         0.82          0.41           0.28           0.21           4.93
                                      -----------  -----------  -------------  -------------  -------------  -------------
  Total from Investment
   Operations.......................        0.66         0.98          0.44           0.50           0.38           5.15
                                      -----------  -----------  -------------  -------------  -------------  -------------
DISTRIBUTIONS
  Net Investment Income.............          --        (0.20)           --          (0.23)         (0.13)         (0.28)
  In Excess of Net Investment
   Income...........................          --           --            --          (0.01)            --             --
  Net Realized Gain.................          --           --            --             --          (0.37)         (2.75)
                                      -----------  -----------  -------------  -------------  -------------  -------------
  Total Distributions...............          --        (0.20)           --          (0.24)         (0.50)         (3.03)
                                      -----------  -----------  -------------  -------------  -------------  -------------
NET ASSET VALUE, END OF PERIOD......   $   10.66    $   11.44     $   11.88      $   12.14      $   12.02      $   14.14
                                      -----------  -----------  -------------  -------------  -------------  -------------
                                      -----------  -----------  -------------  -------------  -------------  -------------
TOTAL RETURN........................        6.60%        9.26%         3.85%          4.33%          3.26%         45.02%
                                      -----------  -----------  -------------  -------------  -------------  -------------
                                      -----------  -----------  -------------  -------------  -------------  -------------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period
 (Thousands)........................   $  18,139    $  36,558     $  45,985      $  73,789      $  97,259      $ 158,112
Ratio of Expenses to Average Net
 Assets (1)(2)......................        0.80%**       0.80%        0.80%**        0.80%          0.80%          0.80%
Ratio of Net Investment Income to
 Average Net Assets (1)(2)..........        2.34%**       1.73%        1.93%**        1.59%          1.44%          1.57%
Portfolio Turnover Rate.............           3%          38%            1%           172%           146%           186%
- ------------------------------
(1) Effect of voluntary expense
    limitation during the period:
     Per share benefit to net
      investment income.............   $    0.03    $    0.02     $    0.01      $    0.02      $    0.01      $    0.01
   Ratios before expense limitation:
     Expenses to Average Net
      Assets........................        1.37%**       1.01%        1.11%**        0.93%          0.89%          0.88%
     Net Investment Income to
      Average Net Assets............        1.77%**       1.52%        1.62%**        1.46%          1.35%          1.49%
</TABLE>
    
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to receive a management  fee calculated at  an annual rate  of 0.60% of  the
    average  daily net  assets of the  Equity Growth Portfolio.  The Adviser has
    agreed to  waive a  portion of  this fee  and/or reimburse  expenses of  the
    Equity  Growth Portfolio to the extent  that the total operating expenses of
    the Equity Growth Portfolio exceed 0.80% of the average daily net assets  of
    the  Class A shares and 1.05% of the average daily net assets of the Class B
    shares. In the  period ended October  31, 1991, the  year ended October  31,
    1992,  the two months ended December 31,  1992, the years ended December 31,
    1993, 1994 and 1995,  the Adviser waived  management fees and/or  reimbursed
    expenses totalling $23,000, $51,000, $22,000, $68,000, $83,000 and $105,000,
    respectively, for the Equity Growth Portfolio.
    
 
 * Commencement of Operations.
** Annualized.
 
                                       6
<PAGE>
                           EMERGING GROWTH PORTFOLIO
   
<TABLE>
<CAPTION>
                                 NOVEMBER 1,                                     TWO MONTHS
                                  1989* TO       YEAR ENDED      YEAR ENDED         ENDED        YEAR ENDED      YEAR ENDED
                                 OCTOBER 31,     OCTOBER 31,     OCTOBER 31,    DECEMBER 31,    DECEMBER 31,    DECEMBER 31,
                                    1990           1991++           1992            1992            1993            1994
                                -------------   -------------   -------------   -------------   -------------   -------------
<S>                             <C>             <C>             <C>             <C>             <C>             <C>
NET ASSET VALUE, BEGINNING OF
 PERIOD.......................  $     10.00     $      9.03     $     16.18     $     14.97     $     16.22     $     16.22
                                -------------   -------------   -------------   -------------   -------------   -------------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment Income/
   (Loss) (1).................         0.08              --           (0.09)          (0.01)          (0.11)          (0.09)
  Net Realized and Unrealized
   Gain/(Loss) on
   Investments................        (1.00)           7.19           (1.12)           1.26            0.11           (0.01)
                                -------------   -------------   -------------   -------------   -------------   -------------
  Total from Investment
   Operations.................        (0.92)           7.19           (1.21)           1.25            0.00           (0.10)
                                -------------   -------------   -------------   -------------   -------------   -------------
DISTRIBUTIONS
  Net Investment Income.......        (0.05)          (0.04)             --              --              --              --
                                -------------   -------------   -------------   -------------   -------------   -------------
NET ASSET VALUE, END OF
 PERIOD.......................  $      9.03     $     16.18     $     14.97     $     16.22     $     16.22     $     16.12
                                -------------   -------------   -------------   -------------   -------------   -------------
                                -------------   -------------   -------------   -------------   -------------   -------------
TOTAL RETURN..................        (9.27)%         79.84%          (7.48)%          8.35%           0.00%          (0.62)%
                                -------------   -------------   -------------   -------------   -------------   -------------
                                -------------   -------------   -------------   -------------   -------------   -------------
RATIO AND SUPPLEMENTAL DATA:
Net Assets, End of Period
 (Thousands)..................  $    11,261     $    54,364     $    80,156     $    94,161     $   103,621     $   117,669
Ratio of Expenses to Average
 Net Assets (1)(2)............         1.26%**         1.25%           1.25%           1.25%**         1.25%           1.25%
Ratio of Net Investment
 Income/ (Loss) to Average Net
 Assets (1)(2)................         0.64%**         0.00%          (0.66)%         (0.68)%**       (0.77)%         (0.61)%
Portfolio Turnover Rate.......           19%              2%             17%              1%             25%             24%
- ------------------------------
(1) Effect of voluntary expense limitation during the period:
     Per share benefit to net
      investment income.......  $      0.01     $      0.02     $      0.01     $      0.00     $      0.01     $     0.002
   Ratios before expense
    limitation:
     Expenses to Average Net
      Assets..................         1.64%           1.39%           1.29%           1.36%**         1.31%           1.26%
     Net Investment Income
      (Loss) to Average Net
      Assets..................         0.24%          (0.14)%         (0.71)%         (0.79)%**       (0.83)%         (0.62)%
 
<CAPTION>
 
                                 YEAR ENDED
                                DECEMBER 31,
                                    1995
                                -------------
<S>                             <C>
NET ASSET VALUE, BEGINNING OF
 PERIOD.......................  $     16.12
                                -------------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment Income/
   (Loss) (1).................        (0.18)
  Net Realized and Unrealized
   Gain/(Loss) on
   Investments................         5.55
                                -------------
  Total from Investment
   Operations.................         5.37
                                -------------
DISTRIBUTIONS
  Net Investment Income.......           --
                                -------------
NET ASSET VALUE, END OF
 PERIOD.......................  $     21.49
                                -------------
                                -------------
TOTAL RETURN..................        33.31%
                                -------------
                                -------------
RATIO AND SUPPLEMENTAL DATA:
Net Assets, End of Period
 (Thousands)..................  $   119,378
Ratio of Expenses to Average
 Net Assets (1)(2)............         1.25%
Ratio of Net Investment
 Income/ (Loss) to Average Net
 Assets (1)(2)................        (0.76)%
Portfolio Turnover Rate.......           25%
- ------------------------------
(1) Effect of voluntary expens
     Per share benefit to net
      investment income.......  $     0.003
   Ratios before expense
    limitation:
     Expenses to Average Net
      Assets..................         1.26%
     Net Investment Income
      (Loss) to Average Net
      Assets..................        (0.77)%
</TABLE>
    
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to  receive a management  fee calculated at  an annual rate  of 1.00% of the
    average daily net assets of the  Emerging Growth Portfolio. The Adviser  has
    agreed  to waive  a portion  of this  fee and/or  reimburse expenses  of the
    Emerging Growth Portfolio to the extent that the total operating expenses of
    the Emerging Growth Portfolio exceed 1.25%  of the average daily net  assets
    of the Class A shares and 1.50% of the average daily net assets of the Class
    B  shares. In the period ended October 31, 1990, the years ended October 31,
    1991 and  1992, the  two months  ended December  31, 1992,  the years  ended
    December  31, 1993, 1994, and 1995 the Adviser waived management fees and/or
    reimbursed expenses totalling $28,000,  $41,000, $31,000, $18,000,  $51,000,
    $16,000 and $18,000, respectively, for the Emerging Growth Portfolio.
    
 
 * Commencement of Operations.
 
   
++ Per  share amounts for the  year ended October 31,  1991 are based on average
   outstanding shares.
    
 
** Annualized.
 
                                       7
<PAGE>
                          AGGRESSIVE EQUITY PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                                                   PERIOD FROM
                                                                                                MARCH 8, 1995* TO
                                                                                                DECEMBER 31, 1995
                                                                                                ------------------
<S>                                                                                             <C>
NET ASSET VALUE, BEGINNING OF PERIOD..........................................................      $    10.00
                                                                                                       -------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)...................................................................            0.15
  Net Realized and Unrealized Gain on Investments.............................................            3.95
                                                                                                       -------
    Total from Investment Operations..........................................................            4.10
                                                                                                       -------
DISTRIBUTIONS
  Net Investment Income.......................................................................           (0.15)
  Net Realized Gain...........................................................................           (1.78)
                                                                                                       -------
  Total Distributions.........................................................................           (1.93)
                                                                                                       -------
NET ASSET VALUE, END OF PERIOD................................................................      $    12.17
                                                                                                       -------
                                                                                                       -------
TOTAL RETURN..................................................................................           41.25%
                                                                                                       -------
                                                                                                       -------
RATIO AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands).........................................................      $   28,548
Ratio of Expenses to Average Net Assets (1)(2)................................................            1.00%**
Ratio of Net Investment Income to Average Net Assets (1)(2)...................................            1.64%**
Portfolio Turnover Rate.......................................................................             309%
- ------------------------
(1) Effect of voluntary expense limitation during the period:
     Per share benefit to net investment income...............................................      $     0.06
   Ratios before expense limitation:
     Expenses to Average Net Assets...........................................................            1.59%**
     Net Investment Income to Average Net Assets..............................................            1.05%**
</TABLE>
    
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to receive a management  fee calculated at  an annual rate  of 0.80% of  the
    average daily net assets of the Aggressive Equity Portfolio. The Adviser has
    agreed  to waive  a portion  of this  fee and/or  reimburse expenses  of the
    Aggressive Equity Portfolio to the extent that the total operating  expenses
    of  the Aggressive  Equity Portfolio exceed  1.00% of the  average daily net
    assets of the Class A  Shares and 1.25% of the  average daily net assets  of
    the  Class B  Shares. In  the period  ended December  31, 1995,  the Adviser
    waived management fees and/or reimbursed expenses totalling $96,000 for  the
    Aggressive Equity Portfolio.
    
 
 * Commencement of Operations
 
** Annualized
 
                                       8
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
 
   
    The   Fund  consists  of  twenty-eight  portfolios,  offering  institutional
investors and high net  worth individual investors a  broad range of  investment
choices coupled with the advantages of a no-load mutual fund with Morgan Stanley
and  its affiliates providing customized  services as Adviser, Administrator and
Distributor. Each portfolio offers Class  A shares and except the  International
Small  Cap, Money Market  and Municipal Money Market  Portfolios, offers Class B
shares. Each portfolio has its own investment objective and policies designed to
meet its specific goals. The investment objective of each Portfolio described in
this Prospectus is as follows:
    
 
   
    - The EQUITY  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation  by
      investing  primarily in  growth-oriented equity  securities of  medium and
      large capitalization companies.
    
 
   
    - The EMERGING  GROWTH PORTFOLIO  seeks  long-term capital  appreciation  by
      investing  primarily  in growth-oriented  equity  securities of  small- to
      medium-sized corporations.
    
 
   
    - The MICROCAP PORTFOLIO seeks  long-term capital appreciation by  investing
      primarily in growth-oriented equity securities of small corporations.
    
 
   
    - The  AGGRESSIVE EQUITY PORTFOLIO is a non-diversified portfolio that seeks
      capital appreciation  by  investing  primarily  in  corporate  equity  and
      equity-linked securities.
    
 
   
    The  other portfolios of the Fund  are described in other Prospectuses which
may be obtained from the Fund at the address and phone number noted on the cover
page of this  Prospectus. The objectives  of these other  portfolios are  listed
below:
    
 
    GLOBAL AND INTERNATIONAL EQUITY:
 
   
    - The   ACTIVE   COUNTRY  ALLOCATION   PORTFOLIO  seeks   long-term  capital
      appreciation by investing in accordance with country weightings determined
      by the Adviser  in equity  securities of  non-U.S. issuers  which, in  the
      aggregate, replicate broad country indices.
    
 
   
    - The  ASIAN  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
      investing primarily in equity securities of Asian issuers.
    
 
   
    - The CHINA GROWTH PORTFOLIO seeks to provide long-term capital appreciation
      by investing primarily  in equity  securities of issuers  in The  People's
      Republic of China, Hong Kong and Taiwan.
    
 
   
    - The  EMERGING MARKETS  PORTFOLIO seeks  long-term capital  appreciation by
      investing primarily in equity securities of emerging country issuers.
    
 
   
    - The EUROPEAN  EQUITY PORTFOLIO  seeks  long-term capital  appreciation  by
      investing primarily in equity securities of European issuers.
    
 
   
    - The  GLOBAL  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation by
      investing primarily in equity securities of issuers throughout the  world,
      including U.S. issuers.
    
 
   
    - The  GOLD  PORTFOLIO  seeks long-term  capital  appreciation  by investing
      primarily in equity securities of foreign and domestic issuers engaged  in
      gold-related activities.
    
 
   
    - The INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of non-U.S. issuers.
    
 
                                       9
<PAGE>
   
    - The INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital appreciation
      by  investing  primarily in  equity  securities of  non-U.S.  issuers with
      equity market capitalizations of less than $1 billion.
    
 
   
    - The JAPANESE  EQUITY PORTFOLIO  seeks  long-term capital  appreciation  by
      investing primarily in equity securities of Japanese issuers.
    
 
   
    - The  LATIN  AMERICAN  PORTFOLIO seeks  long-term  capital  appreciation by
      investing primarily in  equity securities  of Latin  American issuers  and
      debt  securities  issued or  guaranteed by  Latin American  governments or
      governmental entities.
    
 
   
    - The INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of non-U.S. issuers in accordance
      with EAFE  country  (as defined  in  "Investment Objective  and  Policies"
      below) weightings determined by the Adviser.
    
 
    U.S. EQUITY:
 
   
    - The  SMALL CAP VALUE EQUITY PORTFOLIO seeks high long-term total return by
      investing in  undervalued  equity  securities of  small-  to  medium-sized
      companies.
    
 
   
    - The  U. S.  REAL ESTATE PORTFOLIO  seeks to provide  above average current
      income and long-term capital appreciation by investing primarily in equity
      securities of companies in the  U.S. real estate industry, including  real
      estate investment trusts.
    
 
   
    - The  VALUE EQUITY PORTFOLIO seeks high total return by investing in equity
      securities which the Adviser  believes to be  undervalued relative to  the
      stock market in general at the time of purchase.
    
 
    EQUITY AND FIXED INCOME:
    - The BALANCED PORTFOLIO seeks high total return while preserving capital by
      investing  in  a combination  of undervalued  equity securities  and fixed
      income securities.
 
    FIXED INCOME:
 
   
    - The EMERGING MARKETS DEBT PORTFOLIO  seeks high total return by  investing
      primarily   in  debt  securities  of  government,  government-related  and
      corporate issuers located in emerging countries.
    
 
   
    - The FIXED INCOME PORTFOLIO seeks to produce a high total return consistent
      with the preservation of capital  by investing in a diversified  portfolio
      of fixed income securities.
    
 
   
    - The GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real rate
      of return while preserving capital by investing in fixed income securities
      of issuers throughout the world, including U.S. issuers.
    
 
   
    - The  HIGH YIELD PORTFOLIO seeks to maximize total return by investing in a
      diversified portfolio of high yield  fixed income securities that offer  a
      yield  above  that generally  available on  debt  securities in  the three
      highest rating categories of the recognized rating services.
    
 
   
    - The MORTGAGE-BACKED SECURITIES Portfolio seeks to produce as high a  level
      of  current income  as is consistent  with the preservation  of capital by
      investing primarily  in  a  variety  of  investment-grade  mortgage-backed
      securities.
    
 
   
    - The  MUNICIPAL BOND  PORTFOLIO seeks  to produce  a high  level of current
      income  consistent  with  preservation  of  principal  through  investment
      primarily  in municipal obligations, the interest  on which is exempt from
      federal income tax.
    
 
                                       10
<PAGE>
    MONEY MARKET:
 
   
    - The MONEY MARKET PORTFOLIO seeks  to maximize current income and  preserve
      capital  while maintaining high  levels of liquidity  through investing in
      high quality money  market instruments  with remaining  maturities of  one
      year or less.
    
 
   
    - The  MUNICIPAL MONEY MARKET PORTFOLIO seeks to maximize current tax-exempt
      income and preserve  capital while  maintaining high  levels of  liquidity
      through  investing in high quality money market instruments with remaining
      maturities of one year or less which are exempt from federal income tax.
    
 
INVESTMENT MANAGEMENT
 
   
    Morgan Stanley Asset Management  Inc., a wholly  owned subsidiary of  Morgan
Stanley  Group  Inc.,  which,  together  with  its  affiliated  asset management
companies, at December 31, 1995 had approximately $57.4 billion in assets  under
management  as  an  investment  manager  or  as  a  fiduciary  adviser,  acts as
investment adviser to the  Fund and each of  its portfolios. See "Management  of
the Fund -- Investment Adviser" and "Management of the Fund -- Administrator."
    
 
HOW TO INVEST
 
   
    Class  A shares of each  Portfolio are offered directly  to investors at net
asset value with no sales  commission or 12b-1 charges.  Class B shares of  each
Portfolio  are offered at net  asset value with no  sales commission, but with a
12b-1 fee, which  is accrued daily  and paid  quarterly, equal to  0.25% of  the
Class B shares' average daily net assets on an annualized basis. Share purchases
may  be  made  by  sending  investments directly  to  the  Fund  or  through the
Distributor. Shares  in a  Portfolio account  opened prior  to January  2,  1996
(each,  a "Pre-1996 Account") were designated Class A shares on January 2, 1996.
For a Portfolio account opened  on or after January  2, 1996 (a "New  Account"),
the  minimum initial investment is $500,000 for  Class A shares and $100,000 for
Class B shares. Certain exceptions to the foregoing minimums apply to (1) shares
in a Pre-1996  Account with  a value of  $100,000 or  more on March  1, 1996  (a
"Grandfathered Class A Account"); (2) Portfolio accounts held by officers of the
Adviser  and  its  affiliates;  and (3)  certain  advisory  or  asset allocation
accounts, such as Total Funds Management accounts, managed by Morgan Stanley  or
its affiliates, including the Adviser ("Managed Accounts"). The Adviser reserves
the  right in its sole  discretion to determine which  of such advisory or asset
allocation accounts shall be Managed Accounts. For information regarding Managed
Accounts, please contact your Morgan Stanley account representative or the  Fund
at  the telephone number provided  on the cover of  this Prospectus. Shares in a
Pre-1996 Account  with  a value  of  less than  $100,000  on March  1,  1996  (a
"Grandfathered  Class B Account") converted to Class  B shares on March 1, 1996.
The minimum investment levels may be waived at the discretion of the Adviser for
(i) certain employees  and customers  of Morgan  Stanley or  its affiliates  and
certain   trust  departments,  brokers,  dealers,  agents,  financial  planners,
financial services  firms, or  investment  advisers that  have entered  into  an
agreement  with  Morgan  Stanley  or its  affiliates;  and  (ii)  retirement and
deferred compensation plans and trusts used  to fund such plans, including,  but
not  limited to, those defined in Section  401(a), 403(b) or 457 of the Internal
Revenue Code of 1986, as amended, and "rabbi trusts". See "Purchase of Shares --
Minimum Investment  and  Account Sizes;  Conversion  from  Class A  to  Class  B
Shares."
    
 
                                       11
<PAGE>
   
    The  minimum  subsequent investment  for  each Portfolio  account  is $1,000
(except for automatic reinvestment of dividends and capital gains  distributions
for  which there is no minimum). Such  subsequent investments will be applied to
purchase additional  shares  in  the same  class  held  by a  shareholder  in  a
Portfolio account. See "Purchase of Shares -- Additional Investments."
    
 
HOW TO REDEEM
 
   
    Class  A shares or Class  B shares of each Portfolio  may be redeemed at any
time, without cost, at the net asset value per share of shares of the applicable
class next determined after  receipt of the  redemption request. The  redemption
price may be more or less than the purchase price. Certain redemptions may cause
involuntary  redemption or automatic conversion. Class  A or Class B shares held
in  New  Accounts   are  subject  to   involuntary  redemption  if   shareholder
redemption(s)  of such  shares reduces  the value of  such account  to less than
$100,000 for a continuous 60-day  period. Involuntary redemption does not  apply
to  Managed Accounts, Grandfathered  Class A Accounts  and Grandfathered Class B
Accounts, regardless of  the value of  such accounts.  Class A shares  in a  New
Account  will convert  to Class  B shares  if shareholder  redemption(s) of such
shares reduces the value of such account to less than $500,000 for a  continuous
60-day period. Class B shares in a New Account will convert to Class A shares if
shareholder  purchases of additional Class B shares or market activity cause the
value of Class B shares in the New Account to increase to $500,000 or more.  See
"Purchase  of  Shares --  Minimum Account  Sizes  and Involuntary  Redemption of
Shares" and "Redemption of Shares."
    
 
RISK FACTORS
 
    The  investment  policies  of  the  Portfolios  entail  certain  risks   and
considerations of which an investor should be aware. Because the Emerging Growth
and  MicroCap  Portfolios  seek  long-term  capital  appreciation  by  investing
primarily in small- to medium-sized companies and small companies, respectively,
both of which  types of  companies are more  vulnerable to  financial and  other
risks  than larger, more established  companies, investments in these Portfolios
may involve a higher degree of risk and price volatility than the general equity
markets. The Aggressive  Equity Portfolio  may invest  in small-to  medium-sized
companies  to a lesser extent. The  Equity Growth, Emerging Growth, MicroCap and
Aggressive Equity Portfolios may invest in securities of foreign issuers,  which
are  subject to certain risks not typically associated with domestic securities.
See  "Investment   Objectives   and   Policies"   and   "Additional   Investment
Information."  In addition, the Portfolios  may invest in repurchase agreements,
lend their portfolio  securities and  may purchase securities  on a  when-issued
basis.  The Equity Growth and Aggressive Equity Portfolios may invest in covered
call options and may also invest  in stock options, stock futures contracts  and
options  on stock futures contracts, and  may invest in forward foreign currency
exchange contracts to hedge currency risk associated with investment in non-U.S.
dollar-denominated securities.  The Aggressive  Equity Portfolio  may invest  in
convertible  debentures and  specialty equity-linked securities,  such as PERCS,
ELKS or LYONs,  of U.S., and  to a  limited extent, foreign  issuers, which  may
involve  risks  in  addition to  those  associated with  equity  securities. The
Aggressive Equity Portfolio is a non-diversified portfolio under the  Investment
Company  Act of  1940, as amended  (the "1940  Act") and therefore  may invest a
greater proportion  of its  assets in  the  securities of  a smaller  number  of
issuers  and may, as  a result, be subject  to greater risk  with respect to its
portfolio securities. See "Investment  Limitations." See "Additional  Investment
Information."  Each of these investment strategies involves specific risks which
are  described  under  "Investment  Objectives  and  Policies"  and  "Additional
Investment Information" herein and under "Investment Objectives and Policies" in
the Statement of Additional Information.
 
                                       12
<PAGE>
                       INVESTMENT OBJECTIVES AND POLICIES
 
    The investment objective of each Portfolio is described below, together with
the  policies the Fund employs in its  efforts to achieve these objectives. Each
Portfolio's investment  objective  is a  fundamental  policy which  may  not  be
changed without the approval of a majority of the Portfolio's outstanding voting
securities.  There  is  no  assurance  that  the  Portfolios  will  attain their
objectives. The investment policies described below are not fundamental policies
and may be changed without shareholder approval.
 
THE EQUITY GROWTH PORTFOLIO
 
    The  Portfolio's  investment  objective  is  to  provide  long-term  capital
appreciation  by  investing primarily  in  growth-oriented equity  securities of
medium and large capitalization U.S. corporations  and, to a limited extent,  as
described  below, foreign  corporations. With  respect to  the Portfolio, equity
securities include  common and  preferred  stocks, convertible  securities,  and
rights  and warrants to purchase common  stocks. Under normal circumstances, the
Portfolio will invest at least  65% of the value of  its total assets in  equity
securities.
 
    The Adviser employs a flexible and eclectic investment process in pursuit of
the  Portfolio's investment objectives.  In selecting stocks  for the Portfolio,
the Adviser  concentrates  on  a  universe  of  rapidly  growing,  high  quality
companies and lower, but accelerating, earnings growth situations. The Adviser's
universe  of  potential investments  generally  comprises companies  with market
capitalizations of $750  million or  more. The  Portfolio is  not restricted  to
investments   in  specific  market  sectors.   The  Adviser  uses  its  research
capabilities, analytical resources and judgment to assess economic, industry and
market trends, as well as  individual company developments, to select  promising
growth investments for the Portfolio. The Adviser concentrates on companies with
strong,  communicative managements and clearly defined strategies for growth. In
addition,  the  Adviser  rigorously  assesses  company  developments,  including
changes  in strategic direction, management focus  and current and likely future
earnings results. Valuation  is important to  the Adviser but  is viewed in  the
context  of  prospects for  sustainable earnings  growth  and the  potential for
positive earnings surprises vis-a-vis  consensus expectations. The Portfolio  is
free  to invest in any equity security that, in the Adviser's judgment, provides
above average potential for capital appreciation.
 
    In  selecting  investments  for   the  Portfolio,  the  Adviser   emphasizes
individual  security selection.  The Portfolio's  investments will  generally be
diversified by number  of issues  but concentrated sector  positions may  result
from   the  investment  process.  The   Portfolio  has  a  long-term  investment
perspective; however, the Adviser may take advantage of short-term opportunities
that are consistent with the Portfolio's objective by selling recently purchased
securities which have increased in value.
 
    The Portfolio  may invest  up to  25% of  its total  assets at  the time  of
purchase  in  securities  of  foreign companies.  The  Portfolio  may  invest in
securities of foreign issuers  directly or in the  form of Depositary  Receipts.
Investors  should recognize that investing in foreign companies involves certain
special considerations which are not typically associated with investing in U.S.
companies.  See  "Additional  Investment  Information"  herein  and  "Investment
Objectives  and Policies -- Forward Foreign  Currency Exchange Contracts" in the
Statement of Additional Information.
 
    The Portfolio may invest in convertible securities of domestic and,  subject
to  the above  restrictions, foreign  issuers on  occasions when,  due to market
conditions, it  is  more  advantageous  to  purchase  such  securities  than  to
 
                                       13
<PAGE>
purchase  common stock.  Since the Portfolio  invests in both  common stocks and
convertible securities, the risks of investing in the general equity markets may
be tempered to a degree by the Portfolio's investments in convertible securities
which are often not as volatile as common stock.
 
    Any remaining assets may be  invested in certain securities or  obligations,
including   derivative  securities,  as  set  forth  in  "Additional  Investment
Information" below.
 
THE EMERGING GROWTH PORTFOLIO
 
    The  Portfolio's  investment  objective  is  to  provide  long-term  capital
appreciation  by  investing primarily  in  growth-oriented equity  securities of
small- to  medium-sized  domestic  corporations  and, to  a  limited  extent  as
described  below, foreign corporations. The production  of any current income is
incidental to  this  objective.  Such  companies  generally  have  annual  gross
revenues  ranging  from  $10  million  to  $750  million.  With  respect  to the
Portfolio, equity securities  include common and  preferred stocks,  convertible
securities,  and rights and warrants to  purchase common stocks, and any similar
equity interest, such as trust or partnership interests. Such equity  securities
may not pay dividends or distributions and may or may not carry voting rights.
 
    The  Adviser  employs  a  flexible  investment  program  in  pursuit  of the
Portfolio's investment objective. The Portfolio is not restricted to investments
in specific market sectors. The Portfolio will invest in small- to  medium-sized
companies  that are early in their life  cycle, but which have the potential, in
the Adviser's  judgment,  to become  major  enterprises. The  Adviser  uses  its
judgment  and  research capabilities  to assess  economic, industry,  market and
company  developments  to  select  investments  in  promising  emerging   growth
companies  that are expected to  benefit from new technology  or new products or
services. In  addition, the  Adviser  looks for  special developments,  such  as
research  discoveries,  changes in  customer  demand, rejuvenated  management or
basic  changes  in   the  economic  environment.   These  situations  are   only
illustrative  of the types of investments  the Portfolio may make. The Portfolio
is free to invest in any common  stock which in the Adviser's judgment  provides
above-average potential for capital appreciation.
 
    The  Portfolio intends to manage its  investments actively to accomplish its
investment  objective.   Since  the   Portfolio  has   a  long-term   investment
perspective,  the  Adviser  does  not intend  to  respond  to  short-term market
fluctuations or to  acquire securities  for the purpose  of short-term  trading;
however,  the Adviser  may take advantage  of short-term  opportunities that are
consistent with its objective.
 
    The Portfolio  may invest  up to  25% of  its total  assets at  the time  of
purchase  in  securities  of  foreign companies.  The  Portfolio  may  invest in
securities of foreign issuers  directly or in the  form of Depositary  Receipts.
See  "Additional  Investment Information"  below. The  Portfolio may  enter into
forward foreign currency exchange  contracts which provide  for the purchase  or
sale  of  foreign  currencies  in  connection  with  the  settlement  of foreign
securities transactions or to hedge the underlying currency exposure related  to
foreign  investments. The  Portfolio will not  enter into  these commitments for
speculative purposes.  Investors  should  recognize that  investing  in  foreign
companies  involves  certain  special  considerations  which  are  not typically
associated  with  investing  in  U.S.  companies.  See  "Additional   Investment
Information"  herein and "Investment Objectives and Policies -- Forward Currency
Exchange Contracts" in the Statement of Additional Information.
 
   
    The Portfolio may  also invest  in convertible securities  of domestic  and,
subject  to the  above restrictions, foreign  issuers on occasions  when, due to
market conditions, it is more advantageous  to purchase such securities than  to
purchase common stock. The Portfolio will not invest in debt securities that are
not rated at least
    
 
                                       14
<PAGE>
   
investment  grade by either Standard & Poor's Ratings Group or Moody's Investors
Service, Inc. Since the Portfolio invests in both common stocks and  convertible
securities, the risks of investing in the general equity markets may be tempered
to  a degree by the Portfolio's investments in convertible securities, which are
often not as volatile as equity securities.
    
 
    Any remaining assets may be  invested in certain securities or  obligations,
including  derivative securities, that  are set forth  in "Additional Investment
Information" below.
 
THE MICROCAP PORTFOLIO
 
    The  Portfolio's  investment  objective  is  to  provide  long-term  capital
appreciation  by  investing primarily  in  growth-oriented equity  securities of
small domestic corporations and, to a limited extent as described below, foreign
corporations. The  production  of  any  current income  is  incidental  to  this
objective.  Such companies  generally have,  at time  of purchase,  annual gross
revenues of $150 million  or less or market  capitalizations of $250 million  or
less.  With  respect  to the  Portfolio,  equity securities  include  common and
preferred stocks, convertible securities, rights and warrants to purchase common
stocks, and any similar equity interest, such as trust or partnership interests.
Such equity securities may or may not pay dividends or distributions and may  or
may not carry voting rights.
 
    The  Adviser  employs  a  flexible  investment  program  in  pursuit  of the
Portfolio's investment objective. The Portfolio is not restricted to investments
in specific  market sectors.  The Portfolio  will invest  in equity  securities,
including  securities purchased in initial  public offerings, of small companies
that are  early in  their  life cycle,  but which  have  the potential,  in  the
Adviser's judgement, to achieve long-term capital appreciation. The Adviser uses
its  judgment and research capabilities to assess economic, industry, market and
company developments  to  select investments  in  promising companies  that  are
expected  to  benefit  from  new  technology or  new  products  or  services. In
addition,  the  Adviser  looks  for  special  developments,  such  as   research
discoveries, changes in customer demand, rejuvenated management or basic changes
in the economic environment. These situations are only illustrative of the types
of  investments the Portfolio may  make. The Portfolio is  free to invest in any
equity security which in the Adviser's judgment provides above-average potential
for capital appreciation.
 
    The Portfolio intends to manage  its investments actively to accomplish  its
investment   objective.  Since   the  Portfolio   has  a   long-term  investment
perspective, the  Adviser  does  not  intend to  respond  to  short-term  market
fluctuations  or to  acquire securities for  the purpose  of short-term trading;
however, the Adviser  may take  advantage of short-term  opportunities that  are
consistent with its objective.
 
    The  Portfolio may  invest up  to 25%  of its  total assets  at the  time of
purchase in securities of  foreign companies. The Portfolio  may invest in  such
securities  of foreign issuers  directly or in the  form of Depositary Receipts.
See "Additional  Investment Information"  below. The  Portfolio may  enter  into
forward  foreign currency exchange  contracts which provide  for the purchase or
sale of  foreign  currencies  in  connection  with  the  settlement  of  foreign
securities  transactions or to hedge the underlying currency exposure related to
foreign investments. The  Portfolio will  not enter into  these commitments  for
speculative  purposes.  Investors  should recognize  that  investing  in foreign
companies involves  certain  special  considerations  which  are  not  typically
associated   with  investing  in  U.S.  companies.  See  "Additional  Investment
Information" herein and "Investment Objectives and Policies -- Forward  Currency
Exchange Contracts" in the Statement of Additional Information.
 
                                       15
<PAGE>
   
    The  Portfolio may invest in convertible securities of domestic and, subject
to the above  restrictions, foreign  issuers on  occasions when,  due to  market
conditions, it is more advantageous to purchase such securities than to purchase
common  stock. The  Portfolio will  not invest in  debt securities  that are not
rated at least  investment grade by  either Standard &  Poor's Ratings Group  or
Moody's  Investors  Service, Inc.  Since the  Portfolio  invests in  both common
stocks and convertible securities, the risks of investing in the general  equity
markets  may  be  tempered  to  a  degree  by  the  Portfolio's  investments  in
convertible securities, which are  often not as  volatile as equity  securities.
See "Additional Investment Information".
    
 
    Any  remaining assets may be invested  in certain securities or obligations,
including  derivative  securities,  as  set  forth  in  "Additional   Investment
Information" below.
 
THE AGGRESSIVE EQUITY PORTFOLIO
 
    The  Portfolio's investment objective is  to provide capital appreciation by
investing primarily  in  a non-diversified  portfolio  of corporate  equity  and
equity-linked   securities.   With  respect   to   the  Portfolio,   equity  and
equity-linked  securities  include  common  and  preferred  stocks,  convertible
securities, rights and warrants to purchase common stocks, options, futures, and
specialty  securities, such  as ELKS,  LYONs, PERCS  of U.S.,  and to  a limited
extent, as described  below, foreign issuers.  The Aggressive Equity  Fund is  a
non-diversified  portfolio and thus can be more heavily weighted in fewer stocks
than the  Equity  Growth  Portfolio,  which  is  a  diversified  portfolio.  See
"Investment  Limitations." Under normal circumstances, the Portfolio will invest
at least  65% of  the value  of its  total assets  in equity  and  equity-linked
securities.
 
    The Adviser employs a flexible and eclectic investment process in pursuit of
the Portfolio's investment objective. In selecting securities for the Portfolio,
the  Adviser  concentrates  on  a  universe  of  rapidly  growing,  high quality
companies and lower, but accelerating, earnings growth situations. The Adviser's
universe of  potential investments  generally  comprises companies  with  market
capitalizations  of  $500  million  or more  but  smaller  market capitalization
securities may be purchased from time  to time. The Portfolio is not  restricted
to  investments  in  specific  market sectors.  The  Adviser  uses  its research
capabilities, analytical resources and judgment to assess economic, industry and
market trends, as well as  individual company developments, to select  promising
investments  for  the  Portfolio.  The Adviser  concentrates  on  companies with
strong, communicative managements and clearly defined strategies for growth.  In
addition,  the Adviser rigorously  assesses earnings results.  The Adviser seeks
companies which will deliver surprisingly  strong earnings growth. Valuation  is
of secondary importance to the Adviser and is viewed in the context of prospects
for  sustainable  earnings  growth  and  the  potential  for  positive  earnings
surprises in relation to consensus expectations. The Portfolio is free to invest
in any  equity  or  equity-linked  security that,  in  the  Adviser's  judgment,
provides above average potential for capital appreciation.
 
    The  Portfolio may  from time to  time and consistent  with applicable legal
requirements sell securities  short that it  owns (i.e., "against  the box")  or
borrows. See "Additional Investment Information".
 
    In   selecting  investments  for  the   Portfolio,  the  Adviser  emphasizes
individual  security  selection.  Overweighted   sector  positions  and   issuer
positions  may result from the investment process. See "Investment Limitations."
The Portfolio has a long-term  investment perspective; however, the Adviser  may
take  advantage  of  short-term  opportunities  that  are  consistent  with  the
Portfolio's objective  by  selling  recently  purchased  securities  which  have
increased in value.
 
                                       16
<PAGE>
    The  Portfolio may invest in equity and equity-linked securities of domestic
and foreign corporations. However, the Portfolio does not expect to invest  more
than  25% of its total  assets at the time of  purchase in securities of foreign
companies. The Portfolio may invest in securities of foreign issuers directly or
in the form of American Depositary Receipts ("ADRs"). Investors should recognize
that investing  in foreign  companies  involves certain  special  considerations
which  are  not  typically  associated with  investing  in  U.S.  companies. See
"Additional  Investment  Information"  herein  and  "Investment  Objectives  and
Policies  -- Forward  Foreign Currency Exchange  Contracts" in  the Statement of
Additional Information.
 
    Any remaining assets may be  invested in certain securities or  obligations,
including   derivative  securities,  as  set  forth  in  "Additional  Investment
Information" below.
 
                       ADDITIONAL INVESTMENT INFORMATION
 
CONVERTIBLE SECURITIES, WARRANTS AND EQUITY-LINKED SECURITIES
 
    The Portfolios  may invest  in securities  such as  convertible  securities,
preferred  stock,  warrants  or  other  securities  exchangeable  under  certain
circumstances for  shares  of  common stock.  Warrants  are  instruments  giving
holders the right, but not the obligation, to buy shares of a company at a given
price during a specified period.
 
    The  Aggressive  Equity Portfolio  may  invest in  equity-linked securities,
including, among others,  PERCS, ELKS or  LYONs, which are  securities that  are
convertible  into  or the  value of  which is  based upon  the value  of, equity
securities upon certain terms and conditions. The amount received by an investor
at maturity of such  securities is not fixed  but is based on  the price of  the
underlying  common stock. It is  impossible to predict whether  the price of the
underlying common stock  will rise  or fall.  Trading prices  of the  underlying
common stock will be influenced by the issuer's operational results, by complex,
interrelated  political,  economic, financial,  or  other factors  affecting the
capital markets, the  stock exchanges on  which the underlying  common stock  is
traded  and the market segment of which the issuer is a part. In addition, it is
not possible to predict how equity-linked securities will trade in the secondary
market, which is fairly developed and liquid. The market for such securities may
be  shallow,  however,  and  high  volume  trades  may  be  possible  only  with
discounting.  In addition to the foregoing  risks, the return on such securities
depends on the creditworthiness  of the issuer of  the securities, which may  be
the  issuer of the underlying  securities or a third  party investment banker or
other lender. The creditworthiness of  such third party issuer of  equity-linked
securities may, and often does, exceed the creditworthiness of the issuer of the
underlying  securities.  The advantage  of  using equity-linked  securities over
traditional equity and debt securities is  that the former are income  producing
vehicles  that  may provide  a higher  income  than the  dividend income  on the
underlying equity securities  while allowing some  participation in the  capital
appreciation  of the  underlying equity  securities. Another  advantage of using
equity-linked securities is that they may be used for hedging to reduce the risk
of investing in the generally more volatile underlying equity securities.
 
    The following are three examples of equity-linked securities. The  Portfolio
may  invest in  the securities  described below  or other  similar equity-linked
securities.
 
    PERCS.  Preferred Equity  Redemption Cumulative Stock ("PERCS")  technically
are  preferred  stock  with  some characteristics  of  common  stock.  PERCS are
mandatorily convertible into common stock after a period of time, usually  three
years,  during which  the investors' capital  gains are capped,  usually at 30%.
 
                                       17
<PAGE>
Commonly, PERCS may be  redeemed by the  issuer at any time  or if the  issuer's
common  stock is trading  at a specified  price level or  better. The redemption
price starts at the beginning  of the PERCS duration period  at a price that  is
above  the cap by the amount of the extra dividends the PERCS holder is entitled
to receive relative  to the  common stock  over the  duration of  the PERCS  and
declines  to the cap price shortly before maturity of the PERCS. In exchange for
having the cap on capital gains and  giving the issuer the option to redeem  the
PERCS  at any time or  at the specified common  stock price level, the Portfolio
may be compensated with a substantially  higher dividend yield than that on  the
underlying  common stock.  Investors, such as  the Portfolio,  that seek current
income, find PERCS attractive because a PERCS provides a higher dividend  income
than that paid with respect to a company's common stock.
 
    ELKS.     Equity-Linked  Securities  ("ELKS")   differ  from  ordinary  debt
securities, in that the principal amount  received at maturity is not fixed  but
is  based on the  price of the  issuer's common stock.  ELKS are debt securities
commonly issued in  fully registered form  for a  term of three  years under  an
indenture  trust. At maturity, the holder of  ELKS will be entitled to receive a
principal amount equal to the lesser of  a cap amount, commonly in the range  of
30%  to 55% greater than the current price  of the issuer's common stock, or the
average closing  price  per share  of  the  issuer's common  stock,  subject  to
adjustment  as a  result of  certain dilution  events, for  the 10  trading days
immediately prior to maturity.  Unlike PERCS, ELKS are  commonly not subject  to
redemption  prior to maturity. ELKS usually  bear interest during the three-year
term at a substantially  higher rate than the  dividend yield on the  underlying
common  stock. In exchange for having the cap on the return that might have been
received as capital gains on the  underlying common stock, the Portfolio may  be
compensated  with the higher yield, contingent on how well the underlying common
stock does. Investors,  such as the  Portfolio, that seek  current income,  find
ELKS  attractive because  ELKS provide a  higher dividend income  than that paid
with respect to a company's common stock.
 
    LYONS.   Liquid  Yield Option  Notes  ("LYONs") differ  from  ordinary  debt
securities,  in that the amount  received prior to maturity  is not fixed but is
based on the  price of the  issuer's common stock.  LYONs are zero-coupon  notes
that  sell at a large discount from face  value. For an investment in LYONs, the
Portfolio will  not  receive  any  interest payments  until  the  notes  mature,
typically in 15 to 20 years, when the notes are redeemed at face, or par, value.
The  yield on LYONs, typically, is lower-than-market rate for debt securities of
the same maturity, due in part to  the fact that the LYONs are convertible  into
common stock of the issuer at any time at the option of the holder of the LYONs.
Commonly,  the LYONs are redeemable  by the issuer at  any time after an initial
period or if the issuer's common stock is trading at a specified price level  or
better,  or,  at  the  option  of the  holder,  upon  certain  fixed  dates. The
redemption price  typically is  the purchase  price of  the LYONs  plus  accrued
original  issue  discount  to  the  date of  redemption,  which  amounts  to the
lower-than-market yield. The Portfolio  will receive only the  lower-than-market
yield  unless the  underlying common stock  increases in value  at a substantial
rate. LYONs are  attractive to investors,  like the Portfolio,  when it  appears
that  they will  increase in value  due to the  rise in value  of the underlying
common stock.
 
    DEPOSITARY RECEIPTS.  The Portfolios may invest indirectly in securities  of
foreign  companies through sponsored or unsponsored American Depositary Receipts
("ADRs"), Global  Depositary Receipts  ("GDRs") and  other types  of  Depositary
Receipts  (which,  together with  ADRs  and GDRs,  are  hereinafter collectively
referred to as "Depositary  Receipts"), to the  extent such Depositary  Receipts
are  or become available. Depositary Receipts are not necessarily denominated in
the same currency as the underlying securities. In addition, the issuers of  the
securities  underlying  unsponsored  Depositary Receipts  are  not  obligated to
disclose material
 
                                       18
<PAGE>
information in the U.S. and, therefore, there may be less information  available
regarding  such  issuers  and  there  may  not  be  a  correlation  between such
information and the market value of the Depositary Receipts. ADRs are Depositary
Receipts typically  issued  by  a  U.S.  financial  institution  which  evidence
ownership  interests in  a security  or pool of  securities issued  by a foreign
issuer. GDRs and  other types  of Depositary  Receipts are  typically issued  by
foreign  banks or  trust companies,  although they  also may  be issued  by U.S.
financial institutions, and evidence ownership  interests in a security or  pool
of  securities  issued by  either a  foreign or  a U.S.  corporation. Generally,
Depositary Receipts  in  registered  form  are designed  for  use  in  the  U.S.
securities market and Depositary Receipts in bearer form are designed for use in
securities  markets outside  the U.S. For  purposes of  a Portfolio's investment
policies, the Portfolio's investments in  Depositary Receipts will be deemed  to
be investments in the underlying securities.
 
    FOREIGN  INVESTMENT.  The  Portfolios may invest  in U.S. dollar-denominated
securities of foreign issuers  trading in U.S. markets  and the Emerging  Growth
and  Aggressive  Equity  Portfolios may  invest  in  non-U.S. dollar-denominated
securities of foreign issuers. Investment  in securities of foreign issuers  and
in  foreign branches  of domestic  banks involves  somewhat different investment
risks than those  affecting securities of  U.S. domestic issuers.  There may  be
limited  publicly  available information  with respect  to foreign  issuers, and
foreign issuers are not  generally subject to  uniform accounting, auditing  and
financial  standards  and requirements  comparable to  those applicable  to U.S.
companies. There  may also  be  less government  supervision and  regulation  of
foreign securities exchanges, brokers and listed companies than in the U.S. Many
foreign  securities markets  have substantially  less volume  than U.S. national
securities exchanges, and securities of some foreign issuers are less liquid and
more  volatile  than  securities  of  comparable  domestic  issuers.   Brokerage
commissions  and  other transaction  costs on  foreign securities  exchanges are
generally higher than in the U.S. Dividends and interest paid by foreign issuers
may be subject to  withholding and other foreign  taxes, which may decrease  the
net  return on foreign investments as compared to dividends and interest paid to
the Portfolio by domestic companies. It is not expected that a Portfolio or  its
shareholders  would be able to claim a credit for U.S. tax purposes with respect
to any  such  foreign  taxes.  See  "Taxes."  Additional  risks  include  future
political and economic developments, the possibility that a foreign jurisdiction
might  impose  or change  withholding taxes  on income  payable with  respect to
foreign securities, possible  seizure, nationalization or  expropriation of  the
foreign  issuer  or  foreign  deposits  and  the  possible  adoption  of foreign
governmental restrictions such as exchange controls.
 
   
    Investments in securities of foreign  issuers are frequently denominated  in
foreign  currencies  and,  since  the  Emerging  Growth  and  Aggressive  Equity
Portfolios may also  temporarily hold  uninvested reserves in  bank deposits  in
foreign currencies, the value of the Portfolios' assets measured in U.S. dollars
may  be affected favorably or unfavorably  by changes in currency exchange rates
and in  exchange control  regulations, and  the Portfolios  may incur  costs  in
connection with conversions between various currencies.
    
 
    FORWARD  FOREIGN  CURRENCY  EXCHANGE  CONTRACTS.   The  Emerging  Growth and
Aggressive Equity Portfolios  may enter into  forward foreign currency  exchange
contracts  ("forward contracts"),  that provide for  the purchase or  sale of an
amount of a specified foreign currency at a future date. Purposes for which such
contracts may be used include protecting against a decline in a foreign currency
against the U.S.  dollar between  the trade date  and settlement  date when  the
Portfolio  purchases or sells non-U.S. dollar denominated securities, locking in
 
                                       19
<PAGE>
the  U.S. dollar value of dividends declared on securities held by the Portfolio
and generally  protecting  the U.S.  dollar  value  of securities  held  by  the
Portfolio  against exchange rate fluctuation. Such contracts may also be used as
a protective  measure  against the  effects  of fluctuating  rates  of  currency
exchange  and  exchange control  regulations. While  such forward  contracts may
limit losses to the Portfolio against exchange rate fluctuations, they will also
limit any gains that  may otherwise have been  realized. Such forward  contracts
are  derivative  securities,  in  which the  Portfolio  may  invest  for hedging
purposes. See "Investment Objectives and  Policies -- Forward Currency  Exchange
Contracts" in the Statement of Additional Information.
 
    LOANS  OF PORTFOLIO SECURITIES.  The Portfolios may lend their securities to
brokers, dealers, domestic and foreign banks or other financial institutions for
the purpose of increasing its net investment income. These loans must be secured
continuously by cash or equivalent collateral, or by a letter of credit at least
equal to the  market value  of the securities  loaned plus  accrued interest  or
income.  There may be a risk of delay in recovery of the securities or even loss
of rights  in  the  collateral  should  the  borrower  of  the  securities  fail
financially.  A  Portfolio  will  not enter  into  securities  loan transactions
exceeding, in the aggregate, 33  1/3% of the market  value of its total  assets.
For   more  detailed  information  about  securities  lending,  see  "Investment
Objectives and Policies" in the Statement of Additional Information.
 
    MONEY MARKET INSTRUMENTS.   Each Portfolio is permitted  to invest in  money
market   instruments,  although  the  Portfolios  intend  to  stay  invested  in
securities  satisfying  their  primary   investment  objective  to  the   extent
practical.  Each  Portfolio  may  make money  market  investments  pending other
investment or settlement  for liquidity,  or in adverse  market conditions.  The
money market investments permitted for the Portfolios include obligations of the
United  States  Government and  its agencies  and instrumentalities;  other debt
securities; commercial paper including bank obligations; certificates of deposit
(including Eurodollar certificates of  deposit); and repurchase agreements.  For
more detailed information about these money market investments, see "Description
of Securities and Ratings" in the Statement of Additional Information.
 
    NON-PUBLICLY   TRADED   SECURITIES,   PRIVATE   PLACEMENTS   AND  RESTRICTED
SECURITIES.  The Equity  Growth and Aggressive Equity  Portfolios may invest  in
securities  that are  neither listed  on a  stock exchange  nor traded  over the
counter. Such unlisted equity securities may involve a higher degree of business
and financial risk that  can result in  substantial losses. As  a result of  the
absence of a public trading market for these securities, they may be less liquid
than  publicly traded  securities. Although  these securities  may be  resold in
privately negotiated transactions, the prices realized from these sales could be
less than those  originally paid by  such Portfolios  or less than  what may  be
considered   the  fair  value  of  such  securities.  Further,  companies  whose
securities are not  publicly traded  may not be  subject to  the disclosure  and
other  investor  protection  requirements  which might  be  applicable  if their
securities  were  publicly  traded.  If  such  securities  are  required  to  be
registered  under the securities laws of  one or more jurisdictions before being
resold, the Portfolio may be required to bear the expenses of registration. As a
general matter, the Portfolio may not invest more than 15% of its net assets  in
illiquid  securities,  including  securities  for  which  there  is  no  readily
available secondary  market.  Securities  that  are  not  registered  under  the
Securities  Act  of  1933, as  amended,  but that  can  be offered  and  sold to
qualified institutional  buyers under  Rule  144A under  that  Act will  not  be
included  within the foregoing 15% restriction  if the securities are determined
to be liquid. The Board of Directors has adopted guidelines and delegated to the
Adviser, subject  to  the supervision  of  the  Board of  Directors,  the  daily
function  of determining and  monitoring the liquidity  of Rule 144A securities.
Rule 144A securities may become  illiquid if qualified institutional buyers  are
not interested in acquiring the securities.
 
                                       20
<PAGE>
    REPURCHASE  AGREEMENTS.  The Portfolios may enter into repurchase agreements
with brokers, dealers or  banks that meet the  credit guidelines established  by
the  Fund's Board of Directors. In a  repurchase agreement, the Portfolio buys a
security from a seller  that has agreed  to repurchase it  at a mutually  agreed
upon  date and price, reflecting the interest rate effective for the term of the
agreement. The term of these agreements  is usually from overnight to one  week,
and  never exceeds  one year.  Repurchase agreements  may be  viewed as  a fully
collateralized loan  of money  by the  Portfolio to  the seller.  The  Portfolio
always  receives securities, with a market value  at least equal to the purchase
price (including accrued interest)  as collateral and  this value is  maintained
during  the term  of the  agreement. If the  seller defaults  and the collateral
value declines, the Portfolio might incur a loss. If bankruptcy proceedings  are
commenced  with  respect to  the seller,  the  Portfolio's realization  upon the
collateral may  be  delayed or  limited.  The aggregate  of  certain  repurchase
agreements  and  certain  other  investments  is  limited  as  set  forth  under
"Investment Limitations."
 
   
    SHORT SALES.   The Aggressive Equity  Portfolio may from  time to time  sell
securities  short consistent with applicable legal requirements. A short sale is
a transaction in which the Portfolio would sell securities it either owns or has
the right to acquire at no added cost (i.e., "against the box") or does not  own
(but  has borrowed)  in anticipation  of a  decline in  the market  price of the
securities. When the Portfolio  makes a short sale  of borrowed securities,  the
proceeds  it receives from the sale will be held on behalf of a broker until the
Portfolio replaces the  borrowed securities.  To deliver the  securities to  the
buyer,  the  Portfolio will  need  to arrange  through  a broker  to  borrow the
securities and, in so doing, the Portfolio will become obligated to replace  the
securities  borrowed  at their  market  price at  the  time of  the replacement,
whatever that price may be.  The Portfolio may have to  pay a premium to  borrow
the  securities and must pay any dividends or interest payable on the securities
until they are replaced.
    
 
    The Portfolio's obligation to replace the securities borrowed in  connection
with  a short sale will be secured  by collateral deposited with the broker that
consists of cash, U.S.  Government securities or other  liquid, high grade  debt
obligations.  In  addition, if  the short  sale  is not  "against the  box", the
Portfolio will place  in a segregated  account with the  Custodian an amount  of
cash,  U.S. Government securities  or other liquid,  high grade debt obligations
equal to the difference, if any, between (1) the market value of the  securities
sold  at  the  time they  were  sold short  and  (2) any  cash,  U.S. Government
securities or other liquid, high grade debt obligations deposited as  collateral
with the broker in connection with the short sale (not including the proceeds of
the  short sale). Short sales by the Portfolio involve certain risks and special
considerations. Possible losses from short  sales differ from losses that  could
be  incurred from a purchase of a  security, because losses from short sales may
be unlimited, whereas  losses from  purchases can  equal only  the total  amount
invested.
 
    SMALL  AND MEDIUM-SIZED COMPANIES.  Because the Emerging Growth and MicroCap
Portfolios seek long-term capital appreciation by investing primarily in  small-
to medium-sized companies and small companies, respectively, both of which types
of  companies are more vulnerable to financial and other risks than larger, more
established companies,  investments in  these Portfolios  may involve  a  higher
degree  of  risk  and price  volatility  than  the general  equity  markets. The
Aggressive Equity Portfolio may invest in small- to medium-sized companies to  a
lesser extent.
 
    STOCK  OPTIONS, FUTURES  CONTRACTS AND  OPTIONS IN  FUTURES CONTRACTS.   The
Equity Growth and Aggressive  Equity Portfolios may  write (i.e., sell)  covered
call  options on portfolio  securities. The Equity  Growth and Aggressive Equity
Portfolios may write covered put options  on portfolio securities. By selling  a
covered call option, the Portfolio would become obligated during the term of the
option to deliver the securities underlying
 
                                       21
<PAGE>
the  option should the  option holder choose  to exercise the  option before the
option's termination date. In return for the call it has written, the  Portfolio
will  receive from the purchaser (or option holder) a premium which is the price
of the option, less a  commission charged by a  broker. The Portfolio will  keep
the  premium regardless of whether the option is exercised. By selling a covered
put option, the Portfolio  incurs an obligation to  buy the security  underlying
the  option from the purchaser of the put  at the option's exercise price at any
time during  the option  period, at  the purchaser's  election (certain  options
written by the Portfolio will be exercisable by the purchaser only on a specific
date).  A call option is "covered" if the Portfolio owns the security underlying
the option it has written or has  an absolute or immediate right to acquire  the
security  by holding a call  option on such security,  or maintains a sufficient
amount of cash, cash equivalents or liquid securities to purchase the underlying
security.
 
    Generally, a  put option  is  "covered" if  the  Fund maintains  cash,  U.S.
Government securities or other high grade debt obligations equal to the exercise
price  of the option, or if  the Fund holds a put  option on the same underlying
security with a similar or higher exercise price.
 
    When the Portfolio writes  covered call options, it  augments its income  by
the premiums received and is thereby hedged to the extent of that amount against
a  decline in the price of the underlying securities. The premiums received will
offset a  portion  of  the potential  loss  incurred  by the  Portfolio  if  the
securities  underlying the  options are  ultimately sold  by the  Portfolio at a
loss. However, during the  option period, the Portfolio  has, in return for  the
premium  on the option, given up  the opportunity for capital appreciation above
the exercise price should the market price of the underlying security  increase,
but  has retained the risk  of loss should the  price of the underlying security
decline.
 
    The Equity Growth and the Aggressive Equity Portfolios may write put options
to receive the premiums paid by purchasers (when the Adviser wishes to  purchase
the  security underlying  the option  at a price  lower than  its current market
price, in which case  the Portfolio will  write the covered  put at an  exercise
price  reflecting the lower purchase  price sought) and to  close out a long put
option position.
 
    The Equity Growth and the Aggressive Equity Portfolios may also purchase put
options on  their  portfolio securities  or  call options.  When  the  Portfolio
purchases  a call option it acquires the right to buy a designated security at a
designated price (the "exercise price"), and when the Portfolio purchases a  put
option  it acquires  the right  to sell  a designated  security at  the exercise
price, in each  case on  or before a  specified date  (the "termination  date"),
which  is usually not more than nine months  from the date the option is issued.
The Portfolio may purchase call options to close out a covered call position  or
to  protect  against an  increase  in the  price  of a  security  it anticipates
purchasing. The Portfolio may purchase put options on securities which it  holds
in its portfolio to protect itself against decline in the value of the security.
If the value of the underlying security were to fall below the exercise price of
the put purchased in an amount greater than the premium paid for the option, the
Portfolio  would incur no  additional loss. The Portfolio  may also purchase put
options to close out written  put positions in a  manner similar to call  option
closing  purchase transactions.  There are  no other  limits on  the Portfolio's
ability to purchase call and put options.
 
    The Equity  Growth  and the  Aggressive  Equity Portfolios  may  enter  into
futures  contracts and options on futures contracts to remain fully invested and
to  reduce  transaction  costs.  The  Portfolio  may  also  enter  into  futures
transactions as a hedge against fluctuations in the price of a security it holds
or  intends to acquire, but  not for speculation or  for achieving leverage. The
Portfolio  may   enter   into  futures   contracts   and  options   on   futures
 
                                       22
<PAGE>
contracts  provided that not more than 5% of the Portfolio's total assets at the
time of entering into the  contract or option is  required as deposit to  secure
obligations  under such contracts  and options, and provided  that not more than
20% of the  Portfolio's total  assets in the  aggregate is  invested in  futures
contracts  and options on futures  contracts (and in options  in the case of the
Equity Growth and the Aggressive Equity Portfolios).
 
    The Equity  Growth and  the Aggressive  Equity Portfolios  may purchase  and
write  call  and  put  options  on futures  contracts  that  are  traded  on any
international exchange, traded over-the-counter  or which are synthetic  options
or futures or equity swaps, and may enter into closing transactions with respect
to  such  options to  terminate an  existing  position. An  option on  a futures
contract gives  the purchaser  the right  (in return  for the  premium paid)  to
assume a position in a futures contract (a long position if the option is a call
and  a short position if the  option is a put) at  a specified exercise price at
any time during the term  of the option. The  Portfolio will purchase and  write
options on futures contracts for identical purposes to those set forth above for
the  purchase of a futures contract (purchase of  a call option or sale of a put
option) and the sale of a futures contract (purchase of a put option or sale  of
a call option), or to close out a long or short position in future contracts.
 
    Options,  futures and options on futures are derivative securities, in which
the Portfolio  may invest  for hedging  purposes,  as well  as to  remain  fully
invested  and to reduce transaction costs. Investing for the latter two purposes
may be considered  speculative. The  primary risks  associated with  the use  of
options,  futures and options  on futures are  (i) imperfect correlation between
the change in market value of the stocks held by the Portfolio and the prices of
futures and options relating to the  stocks purchased or sold by the  Portfolio;
and  (ii) possible lack of a liquid secondary  market for an option or a futures
contract and the  resulting inability to  close a futures  position which  could
have  an adverse impact on  the Portfolio's ability to  hedge. In the opinion of
the Board of Directors, the risk that the Portfolio will be unable to close  out
a  futures position or options contract will  be minimized by only entering into
futures contracts or options transactions for which there appears to be a liquid
secondary market.
 
    TEMPORARY INVESTMENTS.  During periods in which the Adviser believes changes
in economic, financial or political conditions make it advisable, the Portfolios
may reduce their holdings in equity and other securities for temporary defensive
purposes and the Portfolios may invest  in certain short-term (less than  twelve
months  to maturity) and  medium-term (not greater than  five years to maturity)
debt securities or may hold cash. The short-term and medium-term debt securities
in which  the Portfolio  may invest  consist of  (a) obligations  of the  United
States   or   foreign  country   governments,   their  respective   agencies  or
instrumentalities;  (b)   bank   deposits  and   bank   obligations   (including
certificates  of  deposit, time  deposits  and bankers'  acceptances)  of United
States or foreign country banks denominated  in any currency; (c) floating  rate
securities   and  other  instruments  denominated  in  any  currency  issued  by
international development agencies; (d) finance company and corporate commercial
paper and  other short-term  corporate  debt obligations  of United  States  and
foreign  country corporations meeting the  Portfolio's credit quality standards;
and (e) repurchase agreements with banks and broker-dealers with respect to such
securities. For temporary  defensive purposes, the  Portfolios intend to  invest
only  in short-term and medium-term debt securities that the Adviser believes to
be of high quality, i.e., subject to relatively low risk of loss of interest  or
principal  (there  is currently  no rating  system for  debt securities  to most
foreign countries).
 
    WHEN-ISSUED AND DELAYED  DELIVERY SECURITIES.   The Portfolios may  purchase
securities  on a  when-issued or delayed  delivery basis.  In such transactions,
instruments are bought with payment and  delivery taking place in the future  in
order  to secure what is considered to be  an advantageous yield or price at the
time of the
 
                                       23
<PAGE>
transaction. Delivery of and payment for these securities may take as long as  a
month  or more after the date of the purchase commitment, but will take place no
more than 120 days after  the trade date. The  Portfolio will maintain with  the
Custodian  a separate  account with  a segregated  portfolio of  high-grade debt
securities or cash in an amount at least equal to these commitments. The payment
obligation and the interest rates  that will be received  are each fixed at  the
time  a Portfolio  enters into  the commitment  and no  interest accrues  to the
Portfolio until settlement. Thus,  it is possible that  the market value at  the
time  of settlement  could be  higher or  lower than  the purchase  price if the
general level of  interest rates  has changed.  It is  a current  policy of  the
Portfolios   not  to  enter  into  when-issued  commitments  exceeding,  in  the
aggregate, 15% of the Portfolio's net assets other than the obligations  created
by these commitments.
 
                             INVESTMENT LIMITATIONS
 
    Except  for the MicroCap and Aggressive Equity Portfolios, each Portfolio is
a diversified  investment company  and  is therefore  subject to  the  following
fundamental  limitations: (a) as to 75% of its total assets, a Portfolio may not
invest more than 5%  of its total  assets in the securities  of any one  issuer,
except   obligations   of   the   U.S.   Government   and   its   agencies   and
instrumentalities, and  (b)  a  Portfolio may  not  own  more than  10%  of  the
outstanding voting securities of any one issuer.
 
    The MicroCap and Aggressive Equity Portfolios are non-diversified portfolios
under  the 1940 Act, which means that the Portfolios are not limited by the 1940
Act in the proportion of their assets that may be invested in the obligations of
a single issuer. Thus, the Portfolios  may invest a greater proportion of  their
assets  in the securities of a  small number of issuers and  as a result will be
subject to greater risk with respect to their portfolio securities. However, the
Portfolios intend to  comply with  diversification requirements  imposed by  the
Internal  Revenue Code  of 1986, as  amended (the "Code"),  for qualification as
regulated investment companies. See "Investment Limitations" in the Statement of
Additional Information.
 
   
    Each Portfolio also operates under certain investment restrictions that  are
deemed  fundamental limitations and may be changed only with the approval of the
holders of a majority  of such Portfolio's  outstanding shares. See  "Investment
Limitations"  in  the Statement  of  Additional Information.  In  addition, each
Portfolio operates  under  certain  non-fundamental  investment  limitations  as
described  below and in the Statement  of Additional Information. Each Portfolio
may not:  (i) enter  into repurchase  agreements with  more than  seven days  to
maturity  if, as a result, more than 15%  of the market value of the Portfolio's
net assets would be invested in such repurchase agreements and other investments
for which market  quotations are not  readily available or  which are  otherwise
illiquid;  (ii) borrow money,  except from banks  for extraordinary or emergency
purposes, and then only  in amounts up  to 10% of the  value of the  Portfolio's
total  assets, taken at  cost at the  time of borrowing;  or purchase securities
while borrowings  exceed 5%  of  its total  assets;  (iii) mortgage,  pledge  or
hypothecate  any assets except in connection  with any such borrowing in amounts
up to 10% of the value of the  Portfolio's net assets at the time of  borrowing;
(iv)  invest in fixed time deposits with a duration of over seven calendar days;
or (v) invest in fixed time deposits  with a duration of from two business  days
to seven calendar days if more than 10% of the Portfolio's total assets would be
invested in these deposits.
    
 
                             MANAGEMENT OF THE FUND
 
    INVESTMENT  ADVISER.  Morgan Stanley Asset Management Inc. is the Investment
Adviser and Administrator of  the Fund and each  of its portfolios. The  Adviser
provides investment advice and portfolio management
 
                                       24
<PAGE>
services  pursuant  to  an Investment  Advisory  Agreement and,  subject  to the
supervision of the  Fund's Board  of Directors,  makes each  of the  Portfolio's
day-to-day  investment  decisions,  arranges  for  the  execution  of  portfolio
transactions and  generally manages  each of  the Portfolio's  investments.  The
Adviser  is entitled  to receive from  each Portfolio an  annual management fee,
payable quarterly, equal to the percentage of average daily net assets set forth
in the table below. However, the Adviser  has agreed to a reduction in the  fees
payable  to it and to reimburse the Portfolios, if necessary, if such fees would
cause the total  annual operating  expenses of  either Portfolio  to exceed  the
respective percentage of average daily net assets set forth below.
 
<TABLE>
<CAPTION>
                                                                  MAXIMUM TOTAL OPERATING
                                                                     EXPENSES AFTER FEE
                                                                           WAIVER
                                                                  ------------------------
                  PORTFOLIO                     MANAGEMENT FEE      CLASS A      CLASS B
- ---------------------------------------------  -----------------  -----------  -----------
<S>                                            <C>                <C>          <C>
Equity Growth Portfolio                                0.60%           0.80%        1.05%
Emerging Growth Portfolio                              1.00%           1.25%        1.50%
MicroCap Portfolio                                     1.25%           1.50%        1.75%
Aggressive Equity Portfolio                            0.80%           1.00%        1.25%
</TABLE>
 
    The  fees payable  by the  Emerging Growth,  MicroCap and  Aggressive Equity
Portfolios  are  higher  than  the  management  fees  paid  by  most  investment
companies,  but  the  Adviser  believes  the fees  are  comparable  to  those of
investment companies with similar investment objectives.
 
   
    The Adviser, with  principal offices  at 1221  Avenue of  the Americas,  New
York,  New  York  10020,  conducts a  worldwide  portfolio  management business,
providing a broad  range of portfolio  management services to  customers in  the
United  States and abroad. At December 31,  1995, the Adviser, together with its
affiliated   asset   management   companies,   managed   investments    totaling
approximately  $57.4 billion, including approximately $41.9 billion under active
management and  $15.5  billion as  Named  Fiduciary or  Fiduciary  Adviser.  See
"Management of the Fund" in the Statement of Additional Information.
    
 
    PORTFOLIO  MANAGERS.  The following  persons have primary responsibility for
managing the Portfolios indicated.
 
   
    EQUITY GROWTH PORTFOLIO  -- KURT  FEUERMAN AND  MARGARET K.  JOHNSON.   Kurt
Feuerman  joined  Morgan Stanley  Asset Management  in July  1993 as  a Managing
Director in  the  Institutional Equity  Group.  Previously Mr.  Feuerman  was  a
Managing  Director of Morgan Stanley  & Co., Incorporated's Research Department,
where he was  responsible for  emerging growth stocks,  gaming and  restaurants.
Before  joining Morgan Stanley,  Mr. Feuerman was a  Managing Director of Drexel
Burnham Lambert, where he had been an equity analyst since 1984. Over the years,
he has been highly  ranked in the Institutional  Investor All American  Research
Poll  in four separate  categories: packaged food,  tobacco, emerging growth and
gaming. Mr. Feuerman earned an M.B.A. from Columbia University in 1982, an  M.A.
from  Syracuse University in  1980, and a  B.A. from McGill  University in 1977.
Margaret Johnson is a Principal  of the Adviser and  a Portfolio Manager in  the
Institutional  Equity Group.  She joined  the Adviser in  1984 and  worked as an
Analyst in the  Marketing and  Fiduciary Advisor  areas. Ms.  Johnson became  an
Equity  Analyst in 1986 and a Portfolio Manager in 1989. Prior to joining Morgan
Stanley, she worked for the New York  City PBS affiliate, WNET, Channel 13.  She
holds  a B.A. degree from Yale College and is a Chartered Financial Analyst. Mr.
Feuerman and  Ms.  Johnson have  had  primary responsibility  for  managing  the
Portfolio's assets since July 1993 and April 1991, respectively.
    
 
                                       25
<PAGE>
    EMERGING  GROWTH PORTFOLIO -- DENNIS G. SHERVA.  Dennis Sherva is a Managing
Director of Morgan Stanley & Co., Incorporated and head of emerging growth stock
investments at the Adviser. He has  had primary responsibility for managing  the
Portfolio's  assets since November  1989. Prior to joining  the Adviser in 1988,
Mr. Sherva was Morgan  Stanley's Director of  Worldwide Research activities  for
five  years  and  maintained  direct responsibility  for  emerging  growth stock
strategy and analysis. As  an analyst following emerging  growth stocks for  the
past  decade, he was rated  number one in the  small growth company category six
times by  Institutional  Investor  magazine's All-America  Research  Team  poll.
Before joining Morgan Stanley in 1977, Mr. Sherva had twelve years of industrial
and investment experience. He serves on the Board of Directors of Morgan Stanley
Venture  Capital Inc. and Morgan Stanley R&D Ventures, Inc. Mr. Sherva graduated
from the  University  of  Minnesota  and  received  an  M.A.  from  Wayne  State
University. He is also a Chartered Financial Analyst.
 
   
    MICROCAP  PORTFOLIO --  DENNIS G. SHERVA.   Information about  Mr. Sherva is
included under the Emerging Growth Portfolio above.
    
 
    AGGRESSIVE EQUITY  PORTFOLIO  --  KURT  FEUERMAN.    Information  about  Mr.
Feuerman is included under the Equity Growth Portfolio above.
 
    ADMINISTRATOR.    The Adviser  also  provides the  Fund  with administrative
services pursuant to  an Administration Agreement.  The services provided  under
the  Administration Agreement are subject to the supervision of the Officers and
the Board of  Directors of  the Fund  and include  day-to-day administration  of
matters  related  to the  corporate existence  of the  Fund, maintenance  of its
records, preparation of reports, supervision of the Fund's arrangements with its
custodian,  and  assistance  in  the  preparation  of  the  Fund's  registration
statements  under  Federal and  State  laws. The  Administration  Agreement also
provides that the Administrator,  through its agents, will  provide to the  Fund
dividend  disbursing and  transfer agent  services. For  its services  under the
Administration Agreement, the Fund  pays the Adviser a  monthly fee which on  an
annual basis equals 0.15% of the average daily net assets of the Portfolio.
 
   
    Under  an agreement between  the Adviser and The  Chase Manhattan Bank, N.A.
("Chase"), Chase  provides certain  administrative services  to the  Fund. In  a
merger  completed on September 1, 1995, Chase succeeded to all of the rights and
obligations under the  U.S. Trust Administration  Agreement between the  Adviser
and  the United  States Trust  Company of New  York ("U.S.  Trust"), pursuant to
which U.S. Trust had  agreed to provide certain  administrative services to  the
Fund.  Pursuant  to  a  delegation  clause  in  the  U.S.  Trust  Administration
Agreement, U.S.  Trust delegated  its administration  responsibilities to  Chase
Global  Funds Services Company ("CGFSC"), formerly known as Mutual Funds Service
Company, which after the  merger with Chase  is a subsidiary  of Chase and  will
continue  to provide  certain administrative services  to the  Fund. The Adviser
supervises and  monitors such  administrative services  provided by  CGFSC.  The
services  provided  under  the  Administration  Agreement  and  the  U.S.  Trust
Administration Agreement are  also subject to  the supervision of  the Board  of
Directors  of the  Fund. The  Board of  Directors of  the Fund  has approved the
provision of services described above  pursuant to the Administration  Agreement
and  the U.S. Trust Administration  Agreement as being in  the best interests of
the Fund. CGFSC's business address  is 73 Tremont Street, Boston,  Massachusetts
02108-3913. For additional information regarding the Administration Agreement or
the  U.S. Trust  Administration Agreement, see  "Management of the  Fund" in the
Statement of Additional Information.
    
 
                                       26
<PAGE>
    DIRECTORS AND OFFICERS.  Pursuant  to the Fund's Articles of  Incorporation,
the  Board of Directors decides  upon matters of general  policy and reviews the
actions of the Fund's  Adviser, Administrator and  Distributor. The Officers  of
the Fund conduct and supervise its daily business operations.
 
    DISTRIBUTOR.   Morgan  Stanley serves  as the  exclusive Distributor  of the
shares of  the Fund.  Under its  Distribution Agreement  with the  Fund,  Morgan
Stanley  sells  shares of  each  Portfolio upon  the  terms and  at  the current
offering price described in this Prospectus. Morgan Stanley is not obligated  to
sell any certain number of shares of any Portfolio.
 
   
    The  Portfolios currently offer  only the classes of  shares offered by this
Prospectus. The Portfolios may in the future offer one or more classes of shares
with features, distribution expenses or  other expenses that are different  from
those  of  the  classes  currently  offered. The  Fund  has  adopted  a  Plan of
Distribution with respect to the Class B shares pursuant to Rule 12b-1 under the
1940 Act (the "Plan").  Under the Plan, the  Distributor is entitled to  receive
from  the  Portfolios  a  distribution  fee, which  is  accrued  daily  and paid
quarterly, of  0.25% of  the Class  B shares'  average daily  net assets  on  an
annualized  basis. The Distributor expects to reallocate  most of its fee to its
investment representatives. The Distributor may, in its discretion,  voluntarily
waive  from time to time all or any  portion of its distribution fee and each of
the Distributor and the Adviser if free  to make additional payments out of  its
own  assets  to  promote  the  sale  of  Fund  shares,  including  payments that
compensate financial  institutions  for  distribution  services  or  shareholder
services.
    
 
    The  Plan is designed to compensate the Distributor for its services, not to
reimburse the Distributor for its expenses,  and the Distributor may retain  any
portion  of the fee that it does not expend in fulfillment of its obligations to
the Fund.
 
    EXPENSES.  Each Portfolio is responsible  for payment of certain other  fees
and  expenses  (including legal  fees,  accountants' fees,  custodial  fees, and
printing and mailing  costs) specified  in the  Administration and  Distribution
Agreements.
 
                               PURCHASE OF SHARES
 
   
    Class A and Class B shares of each Portfolio may be purchased, without sales
commission,  at the net asset  value per share next  determined after receipt of
the purchase order by the Portfolio. See "Valuation of Shares."
    
 
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
 
   
    For a  Portfolio  account  opened  on  or after  January  2,  1996  (a  "New
Account"),  the minimum initial investment and minimum account size are $500,000
for Class  A  shares and  $100,000  for Class  B  shares. Managed  Accounts  may
purchase Class A shares without being subject to such minimum initial investment
or  minimum account size  requirements for a Portfolio  account. Officers of the
Adviser and its affiliates are subject to the minimums for a Portfolio  account,
except  they may purchase Class B shares subject to a minimum initial investment
and minimum account size of $5,000 for a Portfolio account.
    
 
   
    If the value of a New Account containing Class A shares falls below $500,000
(but remains at  or above  $100,000) because of  shareholder redemption(s),  the
Fund  will  notify  the shareholder,  and  if  the account  value  remains below
$500,000 (but remains at or above $100,000) for a continuous 60-day period,  the
Class  A shares  in such  account will  convert to  Class B  shares and  will be
subject to the distribution fee and other features
    
 
                                       27
<PAGE>
applicable to the Class B  shares. The Fund, however,  will not convert Class  A
shares to Class B shares based solely upon changes in the market that reduce the
net  asset value  of shares.  Under current  tax law,  conversions between share
classes are not a taxable event to the shareholder.
 
    Shares in a Portfolio account opened  prior to January 2, 1996 (a  "Pre-1996
Account")  were  designated Class  A  shares on  January  2, 1996.  Shares  in a
Pre-1996 Account  with  a  value  of  $100,000 or  more  on  March  1,  1996  (a
"Grandfathered  Class A Account") remained Class  A shares regardless of account
size thereafter. Except for  shares in a Managed  Account, shares in a  Pre-1996
Account  with a value of  less than $100,000 on  March 1, 1996 (a "Grandfathered
Class B Account") converted  to Class B shares  on March 1, 1996.  Grandfathered
Class A Accounts and Managed Accounts are not subject to conversion from Class A
shares to Class B shares.
 
   
    Investors  may also invest in the Fund  by purchasing shares through a trust
department, broker, dealer, agent, financial planner, financial services firm or
investment adviser.  An  investor  may  be  charged  an  additional  service  or
transaction fee by that institution. The minimum investment levels may be waived
at  the discretion  of the  Adviser for (i)  certain employees  and customers of
Morgan Stanley  or  its  affiliates  and  certain  trust  departments,  brokers,
dealers,  agents, financial  planners, financial  services firms,  or investment
advisers that  have  entered  into  an agreement  with  Morgan  Stanley  or  its
affiliates;  and (ii) retirement and deferred compensation plans and trusts used
to fund such  plans, including,  but not limited  to, those  defined in  Section
401(a),  403(b) or  457 of the  Internal Revenue  Code of 1986,  as amended, and
"rabbi trusts".  The  Fund  reserves  the  right  to  modify  or  terminate  the
conversion  features of  the shares  as stated above  at any  time upon 60-days'
notice to shareholders.
    
 
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
 
   
    If the value of  a New Account falls  below $100,000 because of  shareholder
redemption(s),  the Fund will  notify the shareholder, and  if the account value
remains below  $100,000 for  a  continuous 60-day  period,  the shares  in  such
account  are subject to redemption  by the Fund and,  if redeemed, the net asset
value of  such  shares will  be  promptly paid  to  the shareholder.  The  Fund,
however,  will not redeem  shares based solely  upon changes in  the market that
reduce the net asset value of shares.
    
 
   
    For purposes of redemptions by the Fund, the foregoing minimum account  size
requirements  do not  apply to  New Accounts containing  Class B  shares held by
officers of the Adviser or its affiliates. However, if the value of such account
held by an officer of the Adviser  or its affiliates falls below $5,000  because
of  shareholder redemption(s), the Fund will  notify the shareholder, and if the
account value remains $5,000 for a continuous 60-day period, the shares in  such
account  are subject to redemption  by the Fund and,  if redeemed, the net asset
value of such shares will be promptly paid to the shareholder.
    
 
   
    Grandfathered Class A Accounts, Grandfathered  Class B Accounts and  Managed
Accounts are not subject to involuntary redemption.
    
 
   
    The  Fund  reserves  the  right  to  modify  or  terminate  the  involuntary
redemption features of  the shares  as stated above  at any  time upon  60-days'
notice to shareholders.
    
 
CONVERSION FROM CLASS B TO CLASS A SHARES
 
   
    If the value of Class B shares in a Portfolio account increases, whether due
to  shareholder share  purchases or  market activity,  to $500,000  or more, the
Class B shares  will convert  to Class  A shares.  Under current  tax law,  such
conversion  is not a taxable event to  the shareholder. Class A shares converted
from Class B shares are
    
 
                                       28
<PAGE>
subject to the same minimum account size requirements that are applicable to New
Accounts containing Class A shares, as stated above. The Fund reserves the right
to modify or terminate this conversion feature at any time upon 60-days'  notice
to shareholders.
 
INITIAL PURCHASES DIRECTLY FROM THE FUND
 
   
    The  Fund's determination of an investor's eligibility to purchase shares of
a given class  will take precedence  over the investor's  selection of a  class.
Assuming  the investor is eligible for the  class, the Fund will select the most
favorable class for the investor, if the investor has not done so.
    
 
1) BY CHECK.   An account may  be opened  by completing and  signing an  Account
   Registration Form and mailing it, together with a check ($500,000 minimum for
   Class  A shares  of the  Portfolios and  $100,000 for  Class B  shares of the
   Portfolios, with certain exceptions for  Morgan Stanley employees and  select
   customers)  payable to "Morgan Stanley Institutional Fund, Inc. -- [portfolio
   name]", to:
 
      Morgan Stanley Institutional Fund, Inc.
     P.O. Box 2798
     Boston, Massachusetts 02208-2798
 
   
    Payment will  be accepted only  in U.S. dollars,  unless prior approval  for
  payment by other currencies is given by the Fund. The Classes of shares of the
  Portfolio(s)  to be purchased should be designated on the Account Registration
  Form. For purchases  by check, the  Fund is ordinarily  credited with  Federal
  Funds  within one  business day.  Thus, your  purchase of  shares by  check is
  ordinarily credited to your account at the  net asset value per share of  each
  of the relevant Portfolios determined on the next business day after receipt.
    
 
2) BY  FEDERAL  FUNDS WIRE.   Purchases  may be  made by  having your  bank wire
   Federal Funds to the Fund's bank  account. In order to ensure prompt  receipt
   of your Federal Funds Wire, it is important that you follow these steps:
 
   
A.   Telephone  the Fund  (toll free: 1-800-548-7786)  and provide  us with your
    name, address,  telephone  number,  Social Security  or  Tax  Identification
    Number,  the  portfolio(s) selected,  the class  selected, the  amount being
    wired, and by  which bank.  We will  then provide  you with  a Fund  account
    number.  (Investors with existing accounts should also notify the Fund prior
    to wiring funds.)
    
 
   
B.   Instruct  your  bank to  wire  the  specified amount  to  the  Fund's  Wire
    Concentration  Bank Account (be sure  to have your bank  include the name of
    the portfolio(s)  selected,  the  class  selected  and  the  account  number
    assigned to you) as follows:
    
 
   
    Chase Manhattan Bank, N.A.
    One Manhattan Plaza
    New York, NY 10081-1000
    ABA #021000021
    DDA #91-02-733293
    Attn: Morgan Stanley Institutional Fund, Inc.
    Ref: (Portfolio name, your account number, your account name)
    
 
    Please call the Fund at 1-800-548-7786 prior to wiring funds.
 
                                       29
<PAGE>
C.   Complete  the Account Registration  Form and  mail it to  the address shown
    thereon.
 
  Purchase orders for shares of the  Portfolios which are received prior to  the
  regular  close of the NYSE (currently 4:00 p.m. Eastern Time) will be executed
  at the price computed  on the date  of receipt as long  as the Transfer  Agent
  receives  payment by check or  in Federal Funds prior  to the regular close of
  the NYSE on such day.
 
  Federal Funds purchase orders will be accepted only on a day on which the Fund
  and Chase (the "Custodian Bank") are open for business. Your bank may charge a
  service fee for wiring Federal Funds.
 
3) BY BANK WIRE.   The  same procedure outlined  under "By  Federal Funds  Wire"
   above  must be  followed in  purchasing shares  by bank  wire. However, money
   transferred by bank wire may or may  not be converted into Federal Funds  the
   same  day, depending on the time the  money is received and the bank handling
   the wire. Prior to such conversion, an investor's money will not be invested.
   Your bank may charge a service fee for wiring funds.
 
ADDITIONAL INVESTMENTS
 
   
    You may  add to  your account  at any  time (minimum  additional  investment
$1,000  except  for  automatic  reinvestment  of  dividends  and  capital  gains
distributions for which there are no minimums) by purchasing shares at net asset
value by mailing a check to  the Fund (payable to "Morgan Stanley  Institutional
Fund, Inc. -- [portfolio name]") at the above address or by wiring monies to the
Custodian  Bank as outlined above. It is  very important that your account name,
the portfolio name and the class selected be specified in the letter or wire  to
assure  proper crediting  to your  account. In  order to  insure that  your wire
orders are invested  promptly, you  are requested to  notify one  of the  Fund's
representatives  (toll free: 1-800-548-7786) prior  to the wire date. Additional
investments will be applied to purchase additional shares in the same class held
by a shareholder in a Portfolio account.
    
 
OTHER PURCHASE INFORMATION
 
    The purchase price of the  Class A and Class B  shares of each Portfolio  is
the  net asset value next determined after the order is received. See "Valuation
of Shares." An order received prior to the close of the New York Stock  Exchange
("NYSE"),  which is currently  4:00 p.m. Eastern  Time, will be  executed at the
price computed on the date of receipt; an order received after the close of  the
NYSE  will be executed at the price computed on the next day the NYSE is open as
long as the Transfer Agent receives payment  by check or in Federal Funds  prior
to the regular close of the NYSE on such day.
 
    Although  the legal rights of Class A  and Class B shares will be identical,
the different expenses borne  by each class will  result in different net  asset
values  and dividends. The net  asset value of Class  B shares will generally be
lower than the net asset value of Class A shares as a result of the distribution
expense charged to Class B shares. It  is expected, however, that the net  asset
value  per share of the two classes  will tend to converge immediately after the
recording of dividends  which will  differ by  approximately the  amount of  the
distribution expense accrual differential between the classes.
 
    In  the interest  of economy and  convenience, and because  of the operating
procedures of the Fund, certificates representing shares of the Portfolios  will
not  be issued. All shares  purchased are confirmed to  you and credited to your
account on the Fund's books  maintained by the Adviser  or its agents. You  will
have  the  same  rights  and  ownership  with  respect  to  such  shares  as  if
certificates had been issued.
 
                                       30
<PAGE>
    To ensure that checks are collected by the Fund, withdrawals of  investments
made  by check are  not presently permitted  until payment for  the purchase has
been received,  which may  take up  to eight  business days  after the  date  of
purchase.  As a condition  of this offering,  if a purchase  is cancelled due to
nonpayment or because your check does not clear, you will be responsible for any
loss the Fund or its  agents incur. If you are  already a shareholder, the  Fund
may  redeem shares from your account(s) to  reimburse the Fund or its agents for
any loss. In addition,  you may be prohibited  or restricted from making  future
investments in the Fund.
 
   
    Investors  may  also invest  in the  Fund by  purchasing shares  through the
Distributor.
    
 
EXCESSIVE TRADING
 
   
    Frequent  trades  involving  either   substantial  portfolio  assets  or   a
substantial  portion of your  account or accounts controlled  by you can disrupt
management of a Portfolio and raise its expenses. Consequently, in the  interest
of  all the stockholders  of the Portfolio and  the Portfolio's performance, the
Fund may in its discretion bar  a stockholder that engages in excessive  trading
of  shares of a  Portfolio from further purchases  of shares of  the Fund for an
indefinite period. The  Fund considers  excessive trading  to be  more than  one
purchase  and sale  involving shares  of the  same Portfolio  within any 120-day
period. For example, exchanging shares of Portfolio A for shares of Portfolio B,
then exchanging shares of Portfolio B for shares of Portfolio C of the Fund  and
again  exchanging the shares of  Portfolio C for shares  of Portfolio B within a
120-day period  amounts to  excessive  trading. Two  types of  transactions  are
exempt from these excessive trading restrictions: (1) trades exclusively between
money  market  portfolios,  and (2)  trades  done  in connection  with  an asset
allocation service managed or advised by MSAM and/or any of its affiliates.
    
 
                              REDEMPTION OF SHARES
 
   
    You may  withdraw all  or  any portion  of the  amount  in your  account  by
redeeming  shares at any time. Please note  that purchases made by check are not
permitted to be redeemed until payment of the purchase price has been collected,
which may take up to  eight business days after  purchase. The Fund will  redeem
Class A shares or Class B shares of a Portfolio at the next determined net asset
value  of shares  of the applicable  class. On days  that both the  NYSE and the
Custodian Bank are open for business, the  net asset value per share of each  of
the Portfolios is determined at the close of trading of the NYSE (currently 4:00
p.m.  Eastern  Time).  Shares of  the  Portfolios  may be  redeemed  by  mail or
telephone. No charge is made for redemption. Any redemption may be more or  less
than  the purchase price of  your shares depending on,  among other factors, the
market value of the investment securities held by the Portfolios.
    
 
BY MAIL
 
   
    Each Portfolio will redeem its Class A  shares or Class B shares at the  net
asset  value determined on the  date the request is  received, if the request is
received in "good  order" before  the regular close  of the  NYSE. Your  request
should  be addressed to Morgan Stanley  Institutional Fund, Inc., P.O. Box 2798,
Boston, Massachusetts 02208-2798,  except that deliveries  by overnight  courier
should be addressed to Morgan Stanley Institutional Fund, Inc., c/o Chase Global
Funds Services Company, 73 Tremont Street, Boston, Massachusetts 02108-3913.
    
 
                                       31
<PAGE>
    "Good  order"  means that  the  request to  redeem  shares must  include the
following documentation:
 
   
        (a)  A letter of instruction or a stock assignment specifying the  class
    and  number  of  shares or  dollar  amount  to be  redeemed,  signed  by all
    registered owners  of  the shares  in  the exact  names  in which  they  are
    registered;
    
 
   
        (b)   Any  required   signature  guarantees   (see  "Further  Redemption
    Information" below); and
    
 
   
        (c)   Other supporting  legal documents,  if required,  in the  case  of
    estates,  trusts, guardianships,  custodianships, corporations,  pension and
    profit sharing plans and other organizations.
    
 
    Shareholders who are uncertain of requirements for redemption should consult
with a Morgan Stanley Institutional Fund representative.
 
BY TELEPHONE
 
   
    Provided you have previously elected the Telephone Redemption Option on  the
Account  Registration  Form, you  can  request a  redemption  of your  shares by
calling the Fund  and requesting  the redemption proceeds  be mailed  to you  or
wired  to your bank.  Please contact one of  Morgan Stanley Institutional Fund's
representatives for further details. In times of drastic market conditions,  the
telephone  redemption option  may be difficult  to implement.  If you experience
difficulty in making a telephone redemption, your request may be made by mail or
overnight courier and will be implemented at the net asset value next determined
after it is received. Redemption requests sent to the Fund through express  mail
must  be mailed  to the  address of the  Dividend Disbursing  and Transfer Agent
listed under "General Information". The Fund and the Fund's transfer agent  (the
"Transfer  Agent")  will  employ  reasonable  procedures  to  confirm  that  the
instructions communicated  by telephone  are genuine.  These procedures  include
requiring the investor to provide certain personal identification information at
the  time an account is opened and prior to effecting each transaction requested
by telephone. In addition, all  telephone transaction requests will be  recorded
and   investors  may  be  required  to  provide  additional  telecopied  written
instructions regarding transaction requests. Neither  the Fund nor the  Transfer
Agent will be responsible for any loss, liability, cost or expense for following
instructions received by telephone that either of them reasonably believes to be
genuine.
    
 
    To  change the commercial  bank or account  designated to receive redemption
proceeds, a written  request must  be sent  to the  Fund at  the address  above.
Requests  to change the bank  or account must be  signed by each shareholder and
each signature must be guaranteed.
 
FURTHER REDEMPTION INFORMATION
 
    Normally the  Fund will  make payment  for all  shares redeemed  within  one
business  day of receipt  of the request, but  in no event  will payment be made
more than  seven days  after receipt  of  a redemption  request in  good  order.
However,  payments to investors  redeeming shares which  were purchased by check
will not be made until  payment for the purchase  has been collected, which  may
take up to eight days after the date of purchase. The Fund may suspend the right
of  redemption or postpone the date upon which redemptions are effected at times
when the NYSE is closed, or  under any emergency circumstances as determined  by
the Securities and Exchange Commission (the "Commission").
 
    If  the Board of  Directors determines that  it would be  detrimental to the
best interests of  the remaining  shareholders of  a Portfolio  to make  payment
wholly   or  partly  in   cash,  the  Fund  may   pay  the  redemption  proceeds
 
                                       32
<PAGE>
in whole  or  in part  by  a distribution  in-kind  of securities  held  by  the
Portfolio in lieu of cash in conformity with applicable rules of the Commission.
Distributions-in-kind  will be made in  readily marketable securities. Investors
may incur brokerage charges on the  sale of portfolio securities so received  in
payment of redemptions.
 
    To  protect  your account,  the Fund  and its  agents from  fraud, signature
guarantees are required for  certain redemptions to verify  the identity of  the
person  who has  authorized a redemption  from your account.  Please contact the
Fund for further  information. See "Redemption  of Shares" in  the Statement  of
Additional Information.
 
                              SHAREHOLDER SERVICES
 
   
EXCHANGE FEATURES
    
 
   
    You  may exchange shares  that you own  in the Portfolios  for shares of any
other available  portfolio of  the  Fund (other  than the  International  Equity
Portfolio,  which is  closed to  new investors). In  exchanging for  shares of a
portfolio with more  than one  class, the  class of  shares you  receive in  the
exchange  will be determined in the same  manner as any other purchase of shares
and will not  be based  on the  class of  shares surrendered  for the  exchange.
Consequently,  the same minimum initial investment  and minimum account size for
determining the  class  of shares  received  in  the exchange  will  apply.  See
"Purchase  of Shares."  Shares of  the portfolios  may be  exchanged by  mail or
telephone. The privilege to exchange shares  by telephone is automatic and  made
available  without shareholder election. Before you make an exchange, you should
read the prospectus of the portfolio(s) in which you seek to invest. Because  an
exchange  transaction  is treated  as a  redemption followed  by a  purchase, an
exchange would be considered  a taxable event for  shareholders subject to  tax.
The  exchange privilege  is only available  with respect to  portfolios that are
registered for  sale  in  a  shareholder's  state  of  residence.  The  exchange
privilege  may be modified or  terminated by the Fund  at any time upon 60-days'
notice to shareholders.
    
 
BY MAIL
 
   
    In order to  exchange shares  by mail, you  should include  in the  exchange
request  the name, class of shares and account number of your current portfolio,
the name of  the portfolio(s) and  the class(es) of  shares of the  portfolio(s)
into  which you intend to exchange shares,  and the signatures of all registered
account holders. Send the exchange request to Morgan Stanley Institutional Fund,
P.O. Box 2798, Boston, Massachusetts 02208-2798.
    
 
BY TELEPHONE
 
   
    When exchanging shares by  telephone, have ready the  name, class of  shares
and account number of the current Portfolio, the name(s) of the portfolio(s) and
class(es)  of  shares into  which  you intend  to  exchange shares,  your Social
Security number  or Tax  I.D. number,  and your  account address.  Requests  for
telephone  exchanges received prior to 4:00 p.m. (Eastern Time) are processed at
the close  of business  that  same day  based  on the  net  asset value  of  the
class(es)  of the portfolios  at the close of  business. Requests received after
4:00 p.m. (Eastern Time) are  processed the next business  day based on the  net
asset  value determined  at the  close of business  on such  day. For additional
information  regarding  responsibility  for   the  authenticity  of   telephoned
instructions, see "Redemption of Shares -- By Telephone" above.
    
 
TRANSFER OF REGISTRATION
 
   
    You  may transfer  the registration  of any of  your Fund  shares to another
person by writing  to Morgan Stanley  Institutional Fund, Inc.,  P.O. Box  2798,
Boston,   Massachusetts  02208-2798.  As   in  the  case   of  redemptions,  the
    
 
                                       33
<PAGE>
written request must be received in good order before any transfer can be  made.
Transferring  the  registration of  shares may  affect  the eligibility  of your
account for a given class of a Portfolio's shares and may result in  involuntary
conversion or redemption of your shares. See "Purchase of Shares" above.
 
                              VALUATION OF SHARES
 
   
    The net asset value per share of a class of shares of each of the Portfolios
is  determined by dividing the total market value of the Portfolio's investments
and other assets attributable to  such class, less any liabilities  attributable
to  such class, by the  total number of outstanding shares  of such class of the
Portfolio. Net  asset  value  is  calculated separately  for  each  class  of  a
Portfolio.  Net asset value per share is determined  as of the close of the NYSE
on each day  that the NYSE  is open  for business. Price  information on  listed
securities  is taken from  the exchange where the  security is primarily traded.
Securities listed on a U.S. securities exchange for which market quotations  are
available  are valued at the last quoted sale  price on the day the valuation is
made. Securities listed on a foreign exchange are valued at their closing price.
Unlisted securities and listed securities not  traded on the valuation date  for
which  market quotations are not readily available are valued at a price that is
considered to best  represent fair value  within a  range not in  excess of  the
current  asked price nor  less than the  current bid price.  The current bid and
asked prices are determined  based on the  bid and asked  prices quoted on  such
valuation date by reputable brokers.
    
 
   
    Bonds and other fixed income securities are valued according to the broadest
and  most representative market,  which will ordinarily  be the over-the-counter
market. Net asset value includes interest  on fixed income securities, which  is
accrued  daily.  In addition,  bonds and  other fixed  income securities  may be
valued on the basis of prices provided by a pricing service when such prices are
believed to  reflect  the fair  market  value  of such  securities.  The  prices
provided  by a pricing service are determined without regard to bid or last sale
prices, but take into  account institutional-size trading  in similar groups  of
securities  and any developments related  to the specific securities. Securities
not priced in this manner are valued at the most recently quoted sale price,  or
when  securities exchange valuations are used, at the latest quoted bid price on
the day of valuation. If there is  no such reported sale, the latest quoted  bid
price will be used. Securities purchased with remaining maturities of 60 days or
less are valued at amortized cost, if it approximates market value. In the event
that  amortized  cost  does  not  approximate  market  value,  market  prices as
determined above will be used.
    
 
   
    The value of other assets and securities for which no quotations are readily
available (including  restricted  and  unlisted foreign  securities)  and  those
securities  for which it is inappropriate to determine prices in accordance with
the above-stated procedures  are determined in  good faith at  fair value  using
methods  determined by the  Board of Directors. For  purposes of calculating net
asset value per share, all assets and liabilities initially expressed in foreign
currencies will be translated into U.S. dollars at the mean of the bid price and
asked price of  such currencies against  the U.S.  dollar as quoted  by a  major
bank.
    
 
   
    Although  the legal rights of Class A  and Class B shares will be identical,
the different expenses borne  by each class will  result in different net  asset
values  and dividends for the class.  Dividends will differ by approximately the
amount of the distribution expense  accrual differential among the classes.  The
net  asset value of  Class B shares will  generally be lower  than the net asset
value of the Class A shares as  a result of the distribution expense charged  to
Class B shares.
    
 
                                       34
<PAGE>
                            PERFORMANCE INFORMATION
 
   
    The  Fund may from time to time advertise total return for each class of the
Portfolios. THESE FIGURES ARE BASED ON HISTORICAL EARNINGS AND ARE NOT  INTENDED
TO INDICATE FUTURE PERFORMANCE. The "total return" shows what an investment in a
class  of a Portfolio would have earned over a specified period of time (such as
one, five or ten  years), assuming that all  distributions and dividends by  the
Portfolio were reinvested in the same class on the reinvestment dates during the
period.  Total return  does not  take into account  any federal  or state income
taxes that may be payable on dividends and distributions or upon redemption. The
Fund may  also include  comparative performance  information in  advertising  or
marketing   the  Portfolio's  shares,  including  data  from  Lipper  Analytical
Services,  Inc.,  other  industry  publications,  business  periodicals,  rating
services and market indices.
    
 
   
    The  performance figures  for Class  B shares  will generally  be lower than
those for Class  A shares because  of the  distribution fee charged  to Class  B
shares.
    
 
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
 
   
    All  income dividends and capital gains  distributions for a class of shares
will be automatically reinvested in additional shares of such class at net asset
value, except that,  upon written  notice to  the Fund  or by  checking off  the
appropriate  box in the Distribution Option  Section on the Account Registration
Form, a shareholder  may elect  to receive  income dividends  and capital  gains
distributions in cash.
    
 
   
    The  Emerging  Growth  and  the  MicroCap  Portfolios  expect  to distribute
substantially all of their net investment income in the form of annual dividends
and the Equity Growth and the Aggressive Equity Portfolios expect to  distribute
substantially  all  of their  net  investment income  in  the form  of quarterly
dividends. Net realized gains  for each Portfolio, if  any, after reduction  for
any  available  tax  loss  carryforwards  will  also  be  distributed  annually.
Confirmations of the purchase of shares of each Portfolio through the  automatic
reinvestment  of  income  dividends  and  capital  gains  distributions  will be
provided, pursuant to Rule 10b-10(b) under the Securities Exchange Act of  1934,
as  amended, on  the next  monthly client  statement following  such purchase of
shares. Consequently, confirmations of  such purchases will  not be provided  at
the time of completion of such purchases, as might otherwise be required by Rule
10b-10.
    
 
   
    Undistributed  net  investment income  is included  in each  Portfolio's net
assets for the purpose of calculating  net asset value per share. Therefore,  on
the  "ex-dividend" date,  the net  asset value  per share  excludes the dividend
(i.e., is  reduced by  the per  share amount  of the  dividend). Dividends  paid
shortly after the purchase of shares by an investor, although in effect a return
of capital, are taxable to shareholders subject to income tax.
    
 
   
    Because  of  the  distribution  fee  and  any  other  expenses  that  may be
attributable to  the Class  B shares,  the net  income attributable  to and  the
dividends  payable  on  Class  B  shares  will  be  lower  than  the  net income
attributable to and the dividends  payable on Class A  shares. As a result,  the
net asset value per share of the classes of the Portfolios will differ at times.
Expenses of the Portfolio allocated to a particular class of shares thereof will
be borne on a pro rata basis by each outstanding share of that class.
    
 
                                     TAXES
 
   
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
    
 
                                       35
<PAGE>
   
    No  attempt has been made to present  a detailed explanation of the federal,
state, or  local  income tax  treatment  of  a Portfolio  or  its  shareholders.
Accordingly,  shareholders  are urged  to consult  their tax  advisors regarding
specific questions as to federal, state and local income taxes.
    
 
   
    Each Portfolio  is treated  as  a separate  entity  for federal  income  tax
purposes  and  is not  combined with  the  Fund's other  portfolios. It  is each
Portfolio's intent to continue to qualify for the special tax treatment afforded
regulated investment  companies  under the  Code,  so that  the  Portfolio  will
continue to be relieved of federal income tax on that part of its net investment
income and net capital gain that is distributed to shareholders.
    
 
   
    Each  Portfolio distributes substantially  all of its  net investment income
(including, for this purpose, the excess of net short-term capital gain over net
long-term capital  loss)  to  shareholders. Dividends  from  a  Portfolio's  net
investment  income  are  taxable  to shareholders  as  ordinary  income, whether
received in cash  or in additional  shares. Such dividends  paid by a  Portfolio
will  generally qualify for  the 70% dividends-received  deduction for corporate
shareholders to  the  extent  of  qualifying dividend  income  received  by  the
Portfolio  from U.S.  corporations. Each Portfolio  will report  annually to its
shareholders the amount of dividend income qualifying for such treatment.
    
 
   
    Distributions of net capital gain (the excess of net long-term capital  gain
over  net  short-term capital  loss) are  taxable  to shareholders  as long-term
capital gain, regardless of how long  shareholders have held their shares.  Each
Portfolio  sends reports annually to its  shareholders of the federal income tax
status of all distributions made during the preceding year.
    
 
   
    Each  Portfolio  intends   to  make  sufficient   distributions  or   deemed
distributions  of its ordinary income and capital gain net income (the excess of
short-term and long-term  capital gains  over short-term  and long-term  capital
losses),  prior to the end of each  calendar year to avoid liability for federal
excise tax.
    
 
   
    Dividends and  other  distributions  declared by  a  Portfolio  in  October,
November or December of any year and payable to shareholders of record on a date
in  such month will be deemed to have been paid by the Portfolio and received by
the shareholders on December 31  of that year if  the distributions are paid  by
the Portfolio at any time during the following January.
    
 
   
    The  sale, redemption, or exchange  of shares may result  in taxable gain or
loss to the selling, exchanging or redeeming shareholder, depending upon whether
the fair market value of the sale, exchange or redemption proceeds exceeds or is
less than the shareholder's  adjusted basis in the  sold, exchanged or  redeemed
shares.  Any such taxable  gain or loss  generally will be  treated as long-term
capital gain or loss  if the shares have  been held for more  than one year  and
otherwise  generally  will be  treated as  short-term capital  gain or  loss. If
capital gain distributions have been made  with respect to shares that are  sold
at  a loss after  being held for six  months or less, however,  then the loss is
treated as  a  long-term  capital  loss  to  the  extent  of  the  capital  gain
distributions.
    
 
   
    Investment  income  received  by  a Portfolio  from  sources  within foreign
countries may be subject to foreign income taxes withheld at the source. To  the
extent  that a Portfolio is  liable for foreign income  taxes so withheld, it is
not expected that  a Portfolio  or its  shareholders would  be able  to claim  a
credit for U.S. tax purposes with respect to any such foreign taxes.
    
 
   
    The  conversion of Class A shares to Class  B shares should not be a taxable
event to the shareholder.
    
 
                                       36
<PAGE>
   
    Shareholders are urged  to consult  with their tax  advisors concerning  the
application of state and local income taxes to investments in a Portfolio, which
may differ from the federal income tax consequences described above.
    
 
   
    THE   TAX  DISCUSSION  SET  FORTH  ABOVE  IS  INCLUDED  HEREIN  FOR  GENERAL
INFORMATION ONLY. PROSPECTIVE  INVESTORS SHOULD CONSULT  THEIR OWN TAX  ADVISERS
WITH RESPECT TO THE TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN A PORTFOLIO.
    
 
                             PORTFOLIO TRANSACTIONS
 
    The  Investment  Advisory Agreement  authorizes  the Adviser  to  select the
brokers or  dealers that  will execute  the purchases  and sales  of  investment
securities for the Portfolios and directs the Adviser to use its best efforts to
obtain the best available price and most favorable execution with respect to all
transactions  for the  Portfolios. The  Fund has  authorized the  Adviser to pay
higher commissions in recognition of brokerage services which, in the opinion of
the Adviser, are necessary for the achievement of better execution, provided the
Adviser believes this to be in the best interest of the Fund.
 
    Since shares of the Portfolios are not marketed through intermediary brokers
or dealers, it  is not the  Fund's practice to  allocate brokerage or  principal
business  on the basis of sales of shares  which may be made through such firms.
However, the Adviser  may place portfolio  orders with qualified  broker-dealers
who  recommend the  Fund's portfolios or  who act  as agents in  the purchase of
shares of the Fund's portfolios for their clients.
 
    In purchasing and selling  securities for the Portfolios,  it is the  Fund's
policy  to seek to obtain quality execution at the most favorable prices through
responsible  broker-dealers.  In   selecting  broker-dealers   to  execute   the
securities  transactions for the Portfolios, consideration will be given to such
factors as the price of the security,  the rate of the commission, the size  and
difficulty  of  the  order,  the  reliability,  integrity,  financial condition,
general execution and operational capabilities of competing broker-dealers,  and
the  brokerage  and  research services  which  they  provide to  the  Fund. Some
securities considered for investment by  the Portfolios may also be  appropriate
for  other clients served by the Adviser.  If the purchase or sale of securities
consistent with the  investment policies of  the Portfolios and  one or more  of
these  other clients served  by the Adviser  is considered at  or about the same
time, transactions in such securities will be allocated among the Portfolios and
such other  clients in  a manner  deemed  fair and  reasonable by  the  Adviser.
Although  there is  no specified formula  for allocating  such transactions, the
various allocation  methods  used  by  the Adviser,  and  the  results  of  such
allocations, are subject to periodic review by the Fund's Board of Directors.
 
    Subject to the overriding objective of obtaining the best possible execution
of  orders,  the Adviser  may allocate  a portion  of the  Portfolio's brokerage
transactions to Morgan Stanley or broker affiliates of Morgan Stanley. In  order
for  Morgan Stanley or  its affiliates to effect  any portfolio transactions for
the Fund, the commissions, fees or other remuneration received by Morgan Stanley
or such affiliates must be reasonable and fair compared to the commissions, fees
or other  remuneration  paid to  other  brokers in  connection  with  comparable
transactions   involving  similar  securities  being  purchased  or  sold  on  a
securities exchange during a comparable  period of time. Furthermore, the  Board
of    Directors    of    the    Fund,   including    a    majority    of   those
 
                                       37
<PAGE>
Directors who are  not "interested persons,"  as defined in  the 1940 Act,  have
adopted   procedures  which  are   reasonably  designed  to   provide  that  any
commissions,  fees  or  other  remuneration  paid  to  Morgan  Stanley  or  such
affiliates are consistent with the foregoing standard.
 
    Portfolio  securities will not be  purchased from or through,  or sold to or
through, the Adviser or Morgan Stanley  or any "affiliated persons," as  defined
in  the 1940 Act of Morgan Stanley  when such entities are acting as principals,
except to the extent permitted by law.
 
   
    Although none of the Portfolios will invest for short-term trading purposes,
investment securities may be sold from time to time without regard to the length
of time they have been held. For the Equity Growth, Emerging Growth and MicroCap
Portfolios, it  is  anticipated that,  under  normal circumstances,  the  annual
portfolio  turnover rate  will not  exceed 100%.  However, the  annual portfolio
turnover rate of the Equity Growth Portfolio for the fiscal year ended  December
31,  1994 was  146%. For the  Aggressive Equity Portfolio,  the annual portfolio
turnover rate  is expected  to  exceed 100%.  High portfolio  turnover  involves
correspondingly  greater transaction costs  which will be  borne directly by the
respective Portfolio. In addition,  high portfolio turnover  may result in  more
capital  gains  which would  be taxable  to the  shareholders of  the respective
Portfolio.  The  tables  set  forth   in  "Financial  Highlights"  present   the
Portfolios' historical turnover rates.
    
 
                              GENERAL INFORMATION
 
DESCRIPTION OF COMMON STOCK
 
   
    The  Fund was  organized as  a Maryland  corporation on  June 16,  1988. The
Articles of Incorporation, as amended and restated, permit the Fund to issue  up
to  34 billion shares of common stock,  with $.001 par value per share. Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number of shares the  Fund is authorized  to issue without  the approval of  the
shareholders  of the  Fund. Subject  to the  notice period  to shareholders with
respect to shares held by the shareholders, the Board of Directors has the power
to designate one or more classes of  shares of common stock and to classify  and
reclassify  any  unissued shares  with respect  to such  classes. The  shares of
common stock of each  portfolio are currently classified  into two classes,  the
Class  A shares and the Class B  shares, except for the International Small Cap,
Money Market and  Municipal Money Market  Portfolios, which only  offer Class  A
shares.
    
 
   
    The   shares  of   the  Portfolios,  when   issued,  will   be  fully  paid,
nonassessable, fully transferable and  redeemable at the  option of the  holder.
The  shares have no preference as to conversion, exchange, dividends, retirement
or other features and have no  pre-emptive rights. The shares of each  portfolio
have non-cumulative voting rights, which means that the holders of more than 50%
of  the  shares voting  for  the election  of Directors  can  elect 100%  of the
Directors if they choose to do so.  Persons or organizations owning 25% or  more
of  the  outstanding shares  of a  Portfolio  may be  presumed to  "control" (as
defined in the 1940  Act) such Portfolio.  Under Maryland law,  the Fund is  not
required  to hold an annual meeting of its shareholders unless required to do so
under the 1940 Act.
    
 
REPORTS TO SHAREHOLDERS
 
   
    The Fund will send to its  shareholders annual and semi-annual reports;  the
financial  statements  appearing in  annual reports  are audited  by independent
accountants. Monthly unaudited portfolio  data is also  available from the  Fund
upon request.
    
 
                                       38
<PAGE>
   
    In  addition, the Adviser or its agent, as Transfer Agent, will send to each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
    
 
CUSTODIAN
 
    As of September  1, 1995, domestic  securities and cash  are held by  Chase,
which  replaced U.S.  Trust as  the Fund's domestic  custodian. Chase  is not an
affiliate of  the Adviser  or  the Distributor.  Morgan Stanley  Trust  Company,
Brooklyn,  New York ("MSTC"),  an affiliate of the  Adviser and the Distributor,
acts as the Fund's custodian for  foreign assets held outside the United  States
and  employs subcustodians  approved by  the Board of  Directors of  the Fund in
accordance with regulations of  the Securities and  Exchange Commission for  the
purpose  of providing  custodial services  for such  assets. MSTC  may also hold
certain domestic assets for  the Fund. For more  information on the  custodians,
see "General Information -- Custody Arrangements" in the Statement of Additional
Information.
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
    Chase   Global   Funds  Services   Company,   73  Tremont   Street,  Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
 
INDEPENDENT ACCOUNTANTS
 
    Price Waterhouse  LLP serves  as independent  accountants for  the Fund  and
audits the annual financial statements of each Portfolio.
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       39
<PAGE>
<TABLE>
<CAPTION>

   MORGAN STANLEY INSTITUTIONAL FUND, INC.
          EQUITY GROWTH, EMERGING GROWTH, MICROCAP AND 
          AGGRESSIVE EQUITY PORTFOLIOS
          P.O. BOX 2798, BOSTON, MA 02208-2798

- ---------------------------------------------------------------------------------------------------------------

                           ACCOUNT REGISTRATION FORM
- ---------------------------------------------------------------------------------------------------------------
<S>                        <C>
ACCOUNT INFORMATION        If you need assistance in filling out this form     
Fill in where applicable   for the Morgan Stanley Institutional Fund, please   
                           contact your Morgan Stanley representative or call  
                           us toll free 1-(800)-548-7786. Please print all     
                           items except signature, and mail to the Fund at the
                           address above.

- ---------------------------------------------------------------------------------------------------------------
A)  REGISTRATION
    1. INDIVIDUAL            1. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
                                 First Name           Initial              Last Name
    2. JOINT TENANTS         2. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       (RIGHTS OF                First Name           Initial              Last Name
       SURVIVORSHIP            / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       PRESUMED UNLESS           First Name           Initial              Last Name
       TENANCY IN COMMON 
       IS INDICATED)      
- ---------------------------------------------------------------------------------------------------------------
    3. CORPORATIONS,        3.  / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       TRUSTS AND OTHERS       
       Please call the          / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       Fund for additional
       documents that may       / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       be required to set 
       up account and to 
       authorize transactions.
                                Type of / / INCORPORATED / / UNINCORPORATED / / PARTNERSHIP / / UNIFORM GIFT/TRANSFER TO MINOR 
                                Registration:                 ASSOCIATION                   (ONLY ONE CUSTODIAN AND MINOR PERMITTED)


                                / / TRUST __________________________________     / / OTHER (Specify) ______________________________
- ---------------------------------------------------------------------------------------------------------------
B)  MAILING ADDRESS         Street or P.O. Box / / / / / / / / / / / / / / / / / / / / / / / / / / / /

    Please fill in 
    completely, including   City / / / / / / / / / / / / / State / / / Zip / / / / / /-/ / / / / / / / 
    telephone number(s).
                            Home                                   Business
                            Telephone No./ / / /-/ / / /-/ / / / / Telephone No./ / / /-/ / / /-/ / / /
                            / / United States  / / Resident  / /Non-Resident Alien:
                                Citizen            Alien        Indicate Country of Residence _________
- ---------------------------------------------------------------------------------------------------------------
C)  TAXPAYER                PART 1. Enter your Taxpayer         C) IMPORTANT TAX INFORMATION 
    IDENTIFICATION          Identification Number. For most          You (as a payee) are required by
    NUMBER                  individual taxpayers, this is your     law to provide us (as payer) with
    If the account is in    Social Security Number.                your correct Taxpayer Identification
    more than one name,     TAXPAYER IDENTIFICATION NUMBER         Number. Accounts that have a missing
    CIRCLE THE NAME OF THE    / / / /-/ / / / / / / / /            or incorrect Taxpayer Identification
    PERSON WHOSE TAXPAYER               OR                         Number will be subject to backup
    IDENTIFICATION NUMBER       SOCIAL SECURITY NUMBER             withholding at a 31% rate on the dividends,
    IS PROVIDED IN SECTION    / / / /-/ / /-/ / / / /              distributions and other payments.
    A) ABOVE. If no name      PART 2. BACKUP WITHHOLDING           If you have not provided us with
    is circled, the number    / / Check this box if you are        your correct taxpayer identification
    will be considered to be  NOT subject to Backup                number, you may be subject to 
    that of the last name     Withholding under the                a $50 penalty imposed by the Internal
    listed. For Custodian     provisions of Section                Revenue Service.
    account of a minor        3406(a)(1)(C) of the Internal          Backup withholding is not an
    (Uniform Gifts/Transfers  Revenue Code.                        additional tax; the tax liability of
    to Minor Acts), give the                                       persons subject to backup withholding
    Social Security Number                                         will be reduced by the amount of tax
    of the minor.                                                  withheld. If withholding results in
                                                                   an overpayment of taxes, a refund 
                                                                   may be obtained.
                                                                     You may be notified
                                                                   that you are subject to backup 
                                                                   withholding under Section 3406(a)(1)(C)
                                                                   of the Internal Revenue Code because you
                                                                   have underreported interest or dividends
                                                                   or you were required to but failed to
                                                                   file a return which would have included a
                                                                   reportable interest or dividend payment. IF
                                                                   YOU HAVE NOT BEEN SO NOTIFIED, CHECK THE
                                                                   BOX IN PART 2 AT LEFT.

- ---------------------------------------------------------------------------------------------------------------

D)  PORTFOLIO AND          For Purchase of the following Portfolio(s):     
    CLASS SELECTION        Equity Growth Portfolio                      / / Class A Shares $____ / / Class B Shares $____
    (Class A shares        Emerging Growth Portfolio                    / / Class A Shares $____ / / Class B Shares $____
    minimum $500,000       MicroCap Portfolio                           / / Class A Shares $____ / / Class B Shares $____
    for each Portfolio     Aggressive Equity Portfolio                  / / Class A Shares $____ / / Class B Shares $____
    and Class B shares
    minimum $100,000 for                                                Total Initial Investment $_____________
    each Portfolio).
    Please indicate
    Portfolio class and
    amount.

- ---------------------------------------------------------------------------------------------------------------
   
E)  METHOD OF   Payment by:
    INVESTMENT  / / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND, INC.--PORTFOLIO NAME)
    Please
    indicate
    manner of   / / Exchange $____________ From________________       / / / / / / / / / / /-/ /
    payment.                                Name of Portfolio              Account No.

               / / Account previously established by: 

               / / Phone exchange / / Wire on___________________       / / / / / / / / / / / /-/ /
                                                          Date             Account No.            (Check
                                                                 (Previously assigned by the Fund) Digit)
    


 
<PAGE>

- ---------------------------------------------------------------------------------------------------------------

F)  DISTRIBUTION                                       Income dividends and capital gains distributions (if any) will
    OPTION                                             be reinvested in additional shares unless either box below is
                                                       checked.

                                                       / / Income dividends to be paid in cash, capital
                                                           gains distributions (if any) in shares.

                                                      / /  Income dividends and capital gains distributions
                                                           (if any) to be paid in cash.

- ---------------------------------------------------------------------------------------------------------------


G)  TELEPHONE                    / / I/we hereby authorize the Fund and its      ______________________   ________________
    REDEMPTION                       agents to honor any telephone requests      Name of COMMERCIAL Bank  Bank Account No.
    Please select at time of         to wire redemption proceeds to the            (Not Savings Bank)
    initial application if you       commercial bank indicated at right and/or 
    wish to redeem shares by         mail redemption proceeds to the name and                             ________________
    telephone. A SIGNATURE           address in which my/our fund account is                                 Bank ABA No.
    GUARANTEE IS REQUIRED IF         registered if such requests are believed 
    BANK ACCOUNT IS NOT              to be authentic.                           _________________________________________________
    REGISTERED IDENTICALLY TO    The Fund and the Fund's Transfer Agent will    Name(s) in which your BANK Account is Established
    YOUR FUND ACCOUNT.           employ reasonable procedures to confirm that
                                 instructions communicated by telephone are     _________________________________________________
    TELEPHONE REQUESTS FOR       genuine. These procedures include requiring                 Bank's Street Address
    REDEMPTIONS WILL NOT BE      the investor to provide certain personal
    HONORED UNLESS THE BOX IS    identification information at the time an      _________________________________________________
    CHECKED.                     account is opened and prior to effecting each  City                    State                Zip
                                 transaction requested by telephone. In addition,
                                 all telephone transaction requests will be recorded
                                 and investors may be required to provide additional
                                 telecopied written instructions of transaction
                                 requests. Neither the Fund nor the Transfer Agent will
                                 be responsible for any loss, liability, cost or expense
                                 for following instructions received by telephone that
                                 it reasonably believes to be genuine.


- ---------------------------------------------------------------------------------------------------------------

H)  INTERESTED PARTY
    OPTION
    In addition to the account   _________________________________________________________________
    statement sent to my/our                                 Name
    registered address, I/we     _________________________________________________________________
    hereby authorize the fund    
    to mail duplicate            _________________________________________________________________
    statements to the name and                              Address
    address provided at right.
                                 _________________________________________________________________
                                  City                      State                     Zip Code

- ---------------------------------------------------------------------------------------------------------------

I)  DEALER 
    INFORMATION                  _______________________  _______________________________  ___________
                                 Representative Name          Representative No.             Branch No.

- ---------------------------------------------------------------------------------------------------------------

J)  SIGNATURE OF        The  undersigned  certify  that  I/we  have  full  authority  and  legal
    ALL HOLDERS         capacity  to purchase and redeem shares of the Fund and affirm that I/we
    AND TAXPAYER        have received a current Prospectus  of the Morgan Stanley  Institutional
    CERTIFICATION       Fund,  Inc. and agree to  be bound by its  terms. UNDER THE PENALTIES OF
    Sign Here >         PERJURY, I/WE CERTIFY THAT THE INFORMATION PROVIDED IN SECTION C)
                        ABOVE IS TRUE, CORRECT AND COMPLETE.

                        (X)                                 (X)
                        __________________________________  ______________________________________
                        Signature                Date       Signature                  Date

- ---------------------------------------------------------------------------------------------------------------


</TABLE>


<PAGE>
                 (This page has been left blank intentionally.)
<PAGE>
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
 
  NO  DEALER, SALES  REPRESENTATIVE OR ANY  OTHER PERSON HAS  BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE  CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS  HAVING BEEN AUTHORIZED BY THE FUND  OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF  THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION  TO
ANY  PERSON TO WHOM  IT IS UNLAWFUL TO  MAKE SUCH OFFER  OR SOLICITATION IN SUCH
JURISDICTION.
 
                           --------------------------
 
                               TABLE OF CONTENTS
 
   
<TABLE>
<S>                                                 <C>
                                                    PAGE
                                                    ----
Fund Expenses.....................................    2
Financial Highlights..............................    5
Prospectus Summary................................    9
Investment Objectives and Policies................   13
Additional Investment Information.................   17
Investment Limitations............................   24
Management of the Fund............................   25
Purchase of Shares................................   27
Redemption of Shares..............................   31
Shareholder Services..............................   33
Valuation of Shares...............................   34
Performance Information...........................   35
Dividends and Capital Gains Distributions.........   35
Taxes.............................................   36
Portfolio Transactions............................   37
General Information...............................   38
Account Registration Form
</TABLE>
    
 
                            EQUITY GROWTH PORTFOLIO
                           EMERGING GROWTH PORTFOLIO
                               MICROCAP PORTFOLIO
                          AGGRESSIVE EQUITY PORTFOLIO
                               PORTFOLIOS OF THE
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
 
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
 
- ---------------------------------
- ---------------------------------
- ---------------------------------
- ---------------------------------
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
     ----------------------------------------------------------------------
 
                           U.S. REAL ESTATE PORTFOLIO
 
                                PORTFOLIO OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
 
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
                                ----------------
   
    Morgan  Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company, or mutual fund, which offers redeemable shares in
a   series   of   diversified   and   non-diversified   investment    portfolios
("portfolios").   The  Fund   currently  consists   of  twenty-eight  portfolios
representing a  broad range  of  investment choices.  The  Fund is  designed  to
provide clients with attractive alternatives for meeting their investment needs.
This  prospectus (the  "Prospectus") pertains  to the  Class A  and the  Class B
shares of the U.S. Real Estate Portfolio (the "Portfolio"). On January 2,  1996,
the  Portfolio began offering two classes of  shares: the Class A shares and the
Class B  shares,  except  for  the Money  Market,  Municipal  Money  Market  and
International  Small Cap Portfolios which only  offer Class A shares. All shares
of the Portfolio owned prior to January 2, 1996 were redesignated Class A shares
on January 2,  1996. The Class  A and Class  B shares currently  offered by  the
Portfolio  have  different minimum  investment  requirements and  fund expenses.
Shares of  the  portfolios are  offered  with no  sales  charge or  exchange  or
redemption fee (with the exception of the International Small Cap Portfolio).
    
 
    INVESTORS  SHOULD NOTE THAT THE PORTFOLIO MAY  INVEST UP TO 10% OF ITS TOTAL
ASSETS IN RESTRICTED SECURITIES OTHER THAN RULE 144A SECURITIES AND NO MORE THAN
15% OF ITS TOTAL ASSETS IN RESTRICTED SECURITIES THAT ARE RULE 144A  SECURITIES.
SEE  "ADDITIONAL  INVESTMENT  INFORMATION  --  NON-PUBLICLY  TRADED  SECURITIES,
PRIVATE  PLACEMENTS  AND  RESTRICTED  SECURITIES."  INVESTMENTS  IN   RESTRICTED
SECURITIES  IN EXCESS OF  5% OF A  PORTFOLIO'S TOTAL ASSETS  MAY BE CONSIDERED A
SPECULATIVE ACTIVITY, MAY INVOLVE GREATER RISK AND MAY INCREASE THE  PORTFOLIO'S
EXPENSES.
 
    The  Fund is designed  to meet the investment  needs of discerning investors
who place a premium on quality  and personal service. With Morgan Stanley  Asset
Management   Inc.  as   Adviser  and   Administrator  (the   "Adviser"  and  the
"Administrator"), and with Morgan Stanley & Co. Incorporated ("Morgan  Stanley")
as Distributor, the Fund makes available to institutional investors and high net
worth  individual  investors  a  series of  portfolios  which  benefit  from the
investment expertise and commitment to excellence associated with Morgan Stanley
and its affiliates.
   
    This Prospectus is designed to set forth concisely the information about the
Fund that a prospective investor should  know before investing and it should  be
retained  for future reference. The Fund  offers additional portfolios which are
described in other prospectuses and  under "Prospectus Summary" below. The  Fund
currently  offers the following portfolios:  (i) GLOBAL AND INTERNATIONAL EQUITY
- -- Active Country Allocation, Asian  Equity, Emerging Markets, European  Equity,
Global  Equity, Gold, International  Equity, International Magnum, International
Small Cap, Japanese Equity  and Latin American Portfolios;  (ii) U.S. EQUITY  --
Emerging  Growth, Equity  Growth, Aggressive  Equity, MicroCap,  Small Cap Value
Equity, Value Equity  and U.S. Real  Estate Portfolios; (iii)  EQUITY AND  FIXED
INCOME  -- Balanced Portfolio; (iv) FIXED INCOME -- Emerging Markets Debt, Fixed
Income,  Global  Fixed  Income,  High  Yield,  Mortgage-Backed  Securities   and
Municipal  Bond Portfolios; and  (v) MONEY MARKET --  Money Market and Municipal
Money Market Portfolios. Additional information about the Fund is contained in a
"Statement of Additional Information" dated  May 1, 1996, which is  incorporated
herein   by  reference.  The   Statement  of  Additional   Information  and  the
prospectuses pertaining to the other portfolios  of the Fund are available  upon
request  and without charge  by writing or  calling the Fund  at the address and
telephone number set forth above.
    
 
 THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES AND
   EXCHANGE COMMISSION  OR  ANY STATE  SECURITIES  COMMISSION, NOR  HAS  THE
    SECURITIES  AND EXCHANGE COMMISSION OR  ANY STATE SECURITIES COMMISSION
     PASSED  UPON  THE  ACCURACY  OR  ADEQUACY  OF  THIS  PROSPECTUS.   ANY
     REPRESENTATION    TO   THE    CONTRARY   IS    A   CRIMINAL   OFFENSE.
   
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1996.
    
<PAGE>
                                 FUND EXPENSES
 
    The  following table illustrates the expenses and fees that a shareholder of
the Portfolio will incur:
 
<TABLE>
<CAPTION>
SHAREHOLDER TRANSACTION EXPENSES
- --------------------------------------------------
<S>                                                 <C>
Maximum Sales Load Imposed on Purchases
  Class A.........................................     None
  Class B.........................................     None
Maximum Sales Load Imposed on Reinvested Dividends
  Class A.........................................     None
  Class B.........................................     None
Deferred Sales Load
  Class A.........................................     None
  Class B.........................................     None
Redemption Fees
  Class A.........................................     None
  Class B.........................................     None
Exchange Fees
  Class A.........................................     None
  Class B.........................................     None
</TABLE>
 
   
<TABLE>
<CAPTION>
ANNUAL FUND OPERATING EXPENSES
- --------------------------------------------------
 (AS A PERCENTAGE OF AVERAGE NET ASSETS)
<S>                                                 <C>
Management Fee (Net of Fee Waiver)*
  Class A.........................................    0.47%
  Class B.........................................    0.47%
12b-1 Fees
  Class A.........................................     None
  Class B.........................................    0.25%
Other Expenses
  Class A.........................................    0.53%
  Class B.........................................    0.53%
                                                    ---------
Total Operating Expenses (Net of Fee Waivers)*
  Class A.........................................    1.00%
  Class B.........................................    1.25%
                                                    ---------
                                                    ---------
</TABLE>
    
 
- ------------------------
   
*The Adviser has  agreed to waive  its management fees  and/or to reimburse  the
 Portfolio,  if necessary, if such fees would cause the Portfolio's total annual
 operating expenses, as a percentage of average daily net assets, to exceed  the
 percentages set forth in the table above. Absent the fee waiver, the management
 fee  would be  0.80%. Absent the  fee waiver and/or  expense reimbursement, the
 Portfolio's total operating expenses  would be 1.33% of  the average daily  net
 assets  of the Class A shares and 1.58%  of the average daily net assets of the
 Class B shares. As a result of this reduction, the Management Fee stated  above
 is  lower than the contractual  fee stated under "Management  of the Fund." The
 Adviser reserves the right to terminate  any of its fee waivers and/or  expense
 reimbursements  at any time in its  sole discretion. For further information on
 Fund expenses, see "Management of the Fund."
    
 
                                       2
<PAGE>
   
    The purpose of the  table above is to  assist the investor in  understanding
the  various expenses that  an investor in  the Portfolio will  bear directly or
indirectly. The Class  A expenses  and fees for  the Portfolio  based on  actual
figures  for the period ended  December 31, 1995. The  Class B expenses and fees
for the Portfolio are  based on estimates, assuming  that the average daily  net
assets  of  the Class  B shares  of  the Portfolio  will be  $50,000,000. "Other
Expenses" include  Board  of  Directors'  fees  and  expenses,  amortization  of
organizational  costs, filing fees, professional  fees and costs for shareholder
reports. Due to  the continuous nature  of Rule  12b-1 fees, long  term Class  B
shareholders  may pay  more than the  equivalent of the  maximum front-end sales
charges otherwise  permitted by  the  Rules of  Fair  Practice of  the  National
Association of Securities Dealers, Inc. ("NASD").
    
 
    The  following  example illustrates  the expenses  that you  would pay  on a
$1,000 investment assuming (1) a 5% annual rate of return and (2) redemption  at
the  end of each time period. As noted in the table above, the Portfolio charges
no redemption fees of any kind. The example is based on total operating expenses
of the Portfolio after fee waivers.
 
   
<TABLE>
<CAPTION>
                                                                       1 YEAR       3 YEARS      5 YEARS     10 YEARS
                                                                     -----------  -----------  -----------  -----------
<S>                                                                  <C>          <C>          <C>          <C>
U.S. Real Estate Portfolio
  Class A..........................................................   $      10    $      32    $      55    $     122
  Class B..........................................................   $      13    $      40    $      69    $     151
</TABLE>
    
 
    THIS EXAMPLE SHOULD  NOT BE CONSIDERED  A REPRESENTATION OF  PAST OR  FUTURE
EXPENSES  OR  PERFORMANCE. ACTUAL  EXPENSES MAY  BE GREATER  OR LESS  THAN THOSE
SHOWN.
 
    The Fund intends  to comply  with all  state laws  that restrict  investment
company  expenses. Currently, the  most restrictive state  law requires that the
aggregate annual expenses  of an  investment company  shall not  exceed two  and
one-half  percent (2 1/2%) of  the first $30 million  of average net assets, two
percent (2%) of the next $70 million of average net assets, and one and one-half
percent (1 1/2%) of the remaining net assets of such investment company.
 
    The Adviser has agreed to a reduction  in the amounts payable to it, and  to
reimburse  the Portfolio,  if necessary, if  in any  fiscal year the  sum of the
Portfolio's expenses exceeds the limit set by applicable state law.
 
                                       3
<PAGE>
                              FINANCIAL HIGHLIGHTS
 
   
    The following table provides financial highlights for the Class A shares  of
the Portfolio for the period presented. The audited financial highlights for the
Class  A shares for  the period ended December  31, 1995 are  part of the Fund's
financial statements which appear in the Fund's December 31, 1995 Annual  Report
to  Shareholders and  which is  included in  the Fund's  Statement of Additional
Information. The  Portfolio's  financial  highlights for  each  of  the  periods
presented  have been audited by Price  Waterhouse, LLP, whose unqualified report
thereon is also included in the Statement of Additional Information.  Additional
performance information for the Class A shares is included in the Annual Report.
The Annual Report and the financial statements therein, along with the Statement
of Additional Information, are available at no cost from the Fund at the address
and  telephone  number noted  on the  cover page  of this  Prospectus. Financial
highlights are not  available for the  new Class  B shares since  they were  not
offered  as of December  31, 1995. The  following information should  be read in
conjunction with the financial statements and notes thereto.
    
 
                                       4
<PAGE>
                           U.S. REAL ESTATE PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                      PERIOD FROM
                                     FEBRUARY 24,
                                       1995* TO
                                     DECEMBER 31,
                                         1995
                                     -------------
<S>                                  <C>
NET ASSET VALUE, BEGINNING OF
 PERIOD............................  $   10.00
                                     -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)........       0.26
  Net Realized and Unrealized Gain
   on Investments..................       1.84
                                     -------------
  Total from Investment
   Operations......................       2.10
                                     -------------
DISTRIBUTIONS
  Net Investment Income............      (0.24)
  Net Realized Gain................      (0.44)
                                     -------------
    Total Distribution.............      (0.68)
                                     -------------
NET ASSET VALUE, END OF PERIOD.....  $   11.42
                                     -------------
                                     -------------
TOTAL RETURN.......................      21.07%
                                     -------------
                                     -------------
RATIOS AND SUPPLEMENTAL DATA:
  Net Assets, End of Period
   (Thousands).....................  $  69,509
  Ratio of Expenses to Average Net
   Assets (1)(2)...................       1.00%**
  Ratio of Net Investment Income to
   Average Net Assets (1)(2).......       4.04%**
  Portfolio Turnover Rate..........        158%
</TABLE>
    
 
- ------------------------------
 
   
<TABLE>
<S> <C>                                                 <C>
(1) Effect of voluntary expense limitation during the period:
    Per share benefit to net investment income........  $  0.02
    Ratios before expense limitation:
    Expenses to Average Net Assets....................     1.33%**
    Net Investment Income to Average Net Assets.......     3.71%**
</TABLE>
    
 
   
(2) Under the terms of an Investment Advisory Agreement, the Adviser is entitled
    to receive a management  fee calculated at  an annual rate  of 0.80% of  the
    average daily net assets of the Portfolio. The Adviser has agreed to waive a
    portion of this fee and/or reimburse expenses of the Portfolio to the extent
    that  the  total operating  expenses of  the Portfolio  exceed 1.00%  of the
    average daily net  assets of the  Class A  shares and 1.25%  of the  average
    daily  net assets of  the Class B  shares. In the  period ended December 31,
    1995,  the  Adviser  waived  management  fees  and/or  reimbursed   expenses
    totalling $129,000, for the Portfolio.
    
 
 * Commencement of Operations.
 
** Annualized.
 
                                       5
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
   
    The   Fund  consists  of  twenty-eight  portfolios,  offering  institutional
investors and high net  worth individual investors a  broad range of  investment
choices coupled with the advantages of a no-load mutual fund with Morgan Stanley
and  its affiliates providing customized  services as Adviser, Administrator and
Distributor. Each portfolio offers Class A shares and, except the  International
Small Cap, Money Market and Municipal Money Market Portfolios, also offers Class
B  shares. Each portfolio has its own investment objective and policies designed
to meet  specific  goals. The  investment  objective  of the  U.S.  Real  Estate
Portfolio is as follows:
    
 
    -The  U.S.  REAL ESTATE  PORTFOLIO  seeks to  provide  above-average current
     income and long-term capital appreciation by investing primarily in  equity
     securities  of companies in  the U.S. real  estate industry, including real
     estate investment trusts.
 
    The other portfolios of the Fund  are described in other prospectuses  which
may be obtained from the Fund at the address and phone number noted on the cover
page  of this  Prospectus. The objectives  of these other  portfolios are listed
below:
 
    GLOBAL AND INTERNATIONAL EQUITY:
 
   
    -The  ACTIVE   COUNTRY   ALLOCATION  PORTFOLIO   seeks   long-term   capital
     appreciation  by investing in accordance with country weightings determined
     by the  Adviser in  equity securities  of non-U.S.  issuers which,  in  the
     aggregate, replicate broad country indices.
    
 
   
    -The   ASIAN  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing primarily in equity securities of Asian issuers.
    
 
   
    -The CHINA GROWTH PORTFOLIO seeks to provide long-term capital  appreciation
     by  investing primarily in the equity securities of issuers in The People's
     Republic of China, Hong Kong and Taiwan.
    
 
   
    -The EMERGING  MARKETS PORTFOLIO  seeks  long-term capital  appreciation  by
     investing primarily in equity securities of emerging country issuers.
    
 
   
    -The  EUROPEAN  EQUITY  PORTFOLIO seeks  long-term  capital  appreciation by
     investing primarily in equity securities of European issuers.
    
 
   
    -The  GLOBAL  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing  primarily in equity securities  of issuers throughout the world,
     including U.S. issuers.
    
 
   
    -The GOLD  PORTFOLIO  seeks  long-term  capital  appreciation  by  investing
     primarily  in equity securities of foreign  and domestic issuers engaged in
     gold-related activities.
    
 
   
    -The INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation  by
     investing primarily in equity securities of non-U.S. issuers.
    
 
   
    -The  INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation by
     investing primarily in equity securities of non-U.S. issuers in  accordance
     with EAFE country (as defined in "Investment Objective and Policies" below)
     weightings determined by the Adviser.
    
 
   
    -The  INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital appreciation
     by investing primarily in equity securities of non-U.S. issuers with equity
     market capitalizations of less than $1 billion.
    
 
   
    -The JAPANESE  EQUITY  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing primarily in equity securities of Japanese issuers.
    
 
                                       6
<PAGE>
    -The  LATIN  AMERICAN  PORTFOLIO  seeks  long-term  capital  appreciation by
     investing primarily in equity securities of Latin American issuers and debt
     securities  issued  or   guaranteed  by  Latin   American  governments   or
     governmental entities.
 
    U.S. EQUITY:
 
   
    -The  AGGRESSIVE EQUITY  PORTFOLIO seeks  capital appreciation  by investing
     primarily in corporate equity and equity-linked securities.
    
 
   
    -The  EQUITY  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing  primarily  in growth-oriented  equity  securities of  medium and
     large capitalization companies.
    
 
   
    -The EMERGING  GROWTH  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing  primarily  in  growth-oriented equity  securities  of  small- to
     medium-sized corporations.
    
 
   
    -The MICROCAP PORTFOLIO  seeks long-term capital  appreciation by  investing
     primarily in growth-oriented equity securities of small corporations.
    
 
   
    -The  SMALL CAP VALUE EQUITY PORTFOLIO  seeks high long-term total return by
     investing in  undervalued  equity  securities  of  small-  to  medium-sized
     companies.
    
 
   
    -The  VALUE EQUITY PORTFOLIO seeks high  total return by investing in equity
     securities which the  Adviser believes  to be undervalued  relative to  the
     stock market in general at the time of purchase.
    
 
    EQUITY AND FIXED INCOME:
 
    -The  BALANCED PORTFOLIO seeks high total return while preserving capital by
     investing in  a  combination of  undervalued  equity securities  and  fixed
     income securities.
 
    FIXED INCOME:
 
   
    -The  EMERGING MARKETS DEBT  PORTFOLIO seeks high  total return by investing
     primarily  in  debt  securities   of  government,  government-related   and
     corporate issuers located in emerging countries.
    
 
   
    -The  FIXED INCOME PORTFOLIO seeks to produce a high total return consistent
     with the preservation of capital by investing in a diversified portfolio of
     fixed income securities.
    
 
   
    -The GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real  rate
     of  return while preserving capital by investing in fixed income securities
     of issuers throughout the world, including United States issuers.
    
 
   
    -The HIGH YIELD PORTFOLIO seeks to  maximize total return by investing in  a
     diversified  portfolio of high  yield fixed income  securities that offer a
     yield above  that  generally available  on  debt securities  in  the  three
     highest rating categories of the recognized rating services.
    
 
   
    -The  MORTGAGE-BACKED SECURITIES PORTFOLIO seeks to  produce as high a level
     of current income  as is  consistent with  the preservation  of capital  by
     investing  primarily  in  a  variety  of  investment-grade  mortgage-backed
     securities.
    
 
   
    -The MUNICIPAL  BOND PORTFOLIO  seeks to  produce a  high level  of  current
     income   consistent  with  preservation  of  principal  through  investment
     primarily in municipal obligations,  the interest on  which is exempt  from
     federal income tax.
    
 
                                       7
<PAGE>
   
    MONEY MARKET:
    
 
   
    -The  MONEY MARKET PORTFOLIO  seeks to maximize  current income and preserve
     capital while maintaining  high levels  of liquidity  through investing  in
     high quality money market instruments with remaining maturities of one year
     or less.
    
 
   
    -The  MUNICIPAL MONEY MARKET PORTFOLIO  seeks to maximize current tax-exempt
     income and  preserve capital  while maintaining  high levels  of  liquidity
     through  investing in high quality  money market instruments with remaining
     maturities of one year or less which are exempt from federal income tax.
    
   
INVESTMENT MANAGEMENT
    
   
    Morgan Stanley Asset Management  Inc., a wholly  owned subsidiary of  Morgan
Stanley  Group Inc.,  which at December  31, 1995, together  with its affiliated
asset management  companies, had  approximately $57.4  billion in  assets  under
management  as  an  investment  manager  or  as  a  fiduciary  adviser,  acts as
investment adviser to the  Fund and each of  its portfolios. See "Management  of
the Fund -- Investment Adviser" and "Management of the Fund -- Administrator."
    
HOW TO INVEST
   
    Class  A shares of  the Portfolio are  offered directly to  investors at net
asset value with no  sales commission or  12b-1 charges. Class  B shares of  the
Portfolio  are offered at net  asset value with no  sales commission, but with a
12b-1 fee, which  is accrued daily  and paid  quarterly, equal to  0.25% of  the
Class B shares' average daily net assets on an annualized basis. Share purchases
may  be  made  by  sending  investments directly  to  the  Fund  or  through the
Distributor. Shares  in a  Portfolio account  opened prior  to January  2,  1996
(each,  a "Pre-1996 Account") were designated Class A shares on January 2, 1996.
For a Portfolio account opened  on or after January  2, 1996 (a "New  Account"),
the  minimum initial investment is $500,000 for  Class A shares and $100,000 for
Class B shares. Certain exceptions to the foregoing minimums apply to (1) shares
in a Pre-1996  Account with  a value of  $100,000 or  more on March  1, 1996  (a
"Grandfathered Class A Account"); (2) Portfolio accounts held by officers of the
Adviser  and  its  affiliates;  and (3)  certain  advisory  or  asset allocation
accounts, such as Total Funds Management accounts, managed by Morgan Stanley  or
its affiliates, including the Adviser ("Managed Accounts"). The Adviser reserves
the  right in its sole  discretion to determine which  of such advisory or asset
allocation accounts shall be Managed Accounts. For information regarding Managed
Accounts please contact your Morgan  Stanley account representative or the  Fund
at  the telephone number provided  on the cover of  this Prospectus. Shares in a
Pre-1996 Account  with  a value  of  less than  $100,000  on March  1,  1996  (a
"Grandfathered  Class B Account") converted to Class  B shares on March 1, 1996.
The minimum investment levels may be waived at the discretion of the Adviser for
(i) certain employees  and customers  of Morgan  Stanley or  its affiliates  and
certain   trust  departments,  brokers,  dealers,  agents,  financial  planners,
financial services  firms, or  investment  advisers that  have entered  into  an
agreement  with  Morgan  Stanley  or its  affiliates;  and  (ii)  retirement and
deferred compensation plans and trusts used  to fund such plans, including,  but
not  limited to, those defined in Section  401(a), 403(b) or 457 of the Internal
Revenue Code of 1986, as amended, and "rabbi trusts". See "Purchase of Shares --
Minimum Investment  and  Account Sizes;  Conversion  from  Class A  to  Class  B
Shares."
    
 
    The  minimum subsequent investment for a Portfolio account is $1,000 (except
for automatic  reinvestment of  dividends and  capital gains  distributions  for
which  there  is no  minimum). Such  subsequent investments  will be  applied to
purchase additional  shares  in  the same  class  held  by a  shareholder  in  a
Portfolio account. See "Purchase of Shares -- Additional Investments."
 
                                       8
<PAGE>
HOW TO REDEEM
 
    Class  A shares or  Class B shares of  the Portfolio may  be redeemed at any
time, without cost, at the net asset value per share of shares of the applicable
class next determined after  receipt of the  redemption request. The  redemption
price may be more or less than the purchase price. Certain redemptions may cause
involuntary  redemption or automatic conversion. Class  A or Class B shares held
in  New  Accounts   are  subject  to   involuntary  redemption  if   shareholder
redemption(s)  of such  shares reduces  the value of  such account  to less than
$100,000 for any continuous 60-day period. Involuntary redemption does not apply
to Managed Accounts, Grandfathered  Class A Accounts  and Grandfathered Class  B
Accounts,  regardless of  the value of  such accounts.  Class A shares  in a New
Account will convert  to Class  B shares  if shareholder  redemption(s) of  such
shares  reduces  the  value  of  such account  to  less  than  $500,000  for any
continuous 60-day period. Class B shares in a New Account will convert to  Class
A  shares  if  shareholder purchases  of  additional  Class B  shares  or market
activity cause the value of the Class B shares in the New Account to increase to
$500,000 or  more.  See  "Purchase  of  Shares  --  Minimum  Account  Sizes  and
Involuntary Redemption of Shares" and "Redemption of Shares."
 
RISK FACTORS
 
   
    The   investment  policies  of  the   Portfolio  entail  certain  risks  and
considerations of  which an  investor  should be  aware. Because  the  Portfolio
invests primarily in the securities of companies principally engaged in the real
estate industry, its investments may be subject to the risks associated with the
direct  ownership of  real estate.  The Portfolio's  share price  and investment
return fluctuate, and a shareholder's investment when redeemed may be worth more
or less than his original cost. Because  it is expected that the Portfolio  will
invest  a substantial  portion of  its assets  in real  estate investment trusts
("REITs"), the Portfolio may  also be subject to  certain risks associated  with
the  direct investments  of REITs.  Because the  Portfolio is  a non-diversified
portfolio, the Portfolio will invest a  greater proportion of its assets in  the
securities of a smaller number of issuers and, as a result, will be subject to a
greater risk with respect to its portfolio securities. See "Investment Objective
and Policies -- Risk Factors."
    
 
                                       9
<PAGE>
                       INVESTMENT OBJECTIVE AND POLICIES
 
    The  investment objective of the Portfolio is described below, together with
the policies the  Fund employs  in its efforts  to achieve  this objective.  The
Portfolio's  investment  objective  is a  fundamental  policy which  may  not be
changed without the approval of a majority of the Portfolio's outstanding voting
securities. There is no assurance that the Portfolio will attain its objectives.
The investment policies described below are not fundamental policies and may  be
changed without shareholder approval.
 
    The  investment  objective  of the  Portfolio  is to  provide  above average
current income  and long-term  capital appreciation  by investing  primarily  in
equity  securities of companies in the U.S. real estate industry, including real
estate investment  trusts ("REITs").  Equity securities  include common  stocks,
shares  or units of beneficial interest  of REITs, limited partnership interests
in master limited partnerships,  rights or warrants  to purchase common  stocks,
securities convertible into common stocks, and preferred stock.
 
    Under  normal circumstances,  at least 65%  of the  Portfolio's total assets
will be invested in income producing equity securities of companies  principally
engaged  in  the U.S.  real  estate industry.  For  purposes of  the Portfolio's
investment policies,  a company  is  "principally engaged"  in the  real  estate
industry  if (i)  it derives at  least 50% of  its revenues or  profits from the
ownership,  construction,  management,   financing  or   sale  of   residential,
commercial  or industrial real  estate or (ii) it  has at least  50% of the fair
market value of  its assets  invested in residential,  commercial or  industrial
real  estate. Companies  in the real  estate industry may  include among others:
REITs, master limited partnerships that invest in interests in real estate, real
estate operating companies, and companies with substantial real estate holdings,
such as  hotel  companies, residential  builders  and land-rich  companies.  The
Portfolio  seeks  to invest  in equity  securities of  companies that  provide a
dividend  yield  that  exceeds  the  composite  dividend  yield  of   securities
comprising the Standard & Poor's Stock Price Index ("S&P 500").
 
    A  substantial portion of  the Portfolio's total assets  will be invested in
securities of REITs.  REITs pool  investors' funds for  investment primarily  in
income  producing real estate or real estate  related loans or interests. A REIT
is not taxed  on income  distributed to its  shareholders or  unitholders if  it
complies  with regulatory requirements relating  to its organization, ownership,
assets and income, and with a  regulatory requirement that it distribute to  its
shareholders  or unitholders at least 95% of its taxable income for each taxable
year. Generally, REITs  can be  classified as  Equity REITs,  Mortgage REITs  or
Hybrid  REITs. Equity REITs invest the majority of their assets directly in real
property and derive  their income primarily  from rents and  capital gains  from
appreciation   realized  through  property  sales.   Equity  REITs  are  further
categorized according to  the types of  real estate securities  they own,  e.g.,
apartment properties, retail shopping centers, office and industrial properties,
hotels,  health-care facilities, manufactured  housing and mixed-property types.
Mortgage REITs invest the majority of their assets in real estate mortgages  and
derive  their income primarily from interest  payments. Hybrid REITs combine the
characteristics of both  Equity and  Mortgage REITs. The  Portfolio will  invest
primarily in Equity REITs. A shareholder in the Portfolio should realize that by
investing  in REITs indirectly through the Portfolio,  he will bear not only his
proportionate share of the expenses of  the Portfolio, but also indirectly,  the
management expenses of underlying REITs.
 
    Under  normal circumstances, the Portfolio may invest up to 35% of its total
assets in  debt securities  issued or  guaranteed by  real estate  companies  or
secured by real estate assets and rated, at time of purchase, in one of the four
highest   rating  categories  by  a  nationally  recognized  statistical  rating
organization ("NRSRO") or
 
                                       10
<PAGE>
determined by the Adviser to be of  comparable quality at the time of  purchase,
high quality money market instruments, such as notes, certificates of deposit or
bankers'  acceptances issued by domestic or  foreign insures, or high-grade debt
securities, consisting of corporate debt securities and United States Government
securities.  Securities  rated  in  the  lowest  category  of  investment  grade
securities  have  speculative characteristics.  Investment grade  securities are
securities that are rated  in one of  the four highest  rating categories by  an
NRSRO.
 
    Any  remaining assets  not invested  as described  above may  be invested in
certain securities or obligations, including derivative securities, as set forth
in "Additional Investment Information" below.  The Portfolio may concentrate  in
the  U.S. real estate  industry, but may not  invest more than  25% of its total
assets in securities of companies in any one other industry (for these  purposes
the U.S. Government and its agencies and instrumentalities are not considered an
industry).
 
RISK FACTORS
 
    The   investment  policies  of  the   Portfolio  entail  certain  risks  and
considerations of  which an  investor  should be  aware. Because  the  Portfolio
invests primarily in the securities of companies principally engaged in the real
estate industry, its investments may be subject to the risks associated with the
direct  ownership of  real estate. These  risks include: the  cyclical nature of
real estate  values, risks  related to  general and  local economic  conditions,
overbuilding   and  increased  competition,  increases  in  property  taxes  and
operating expenses, demographic trends and variations in rental income,  changes
in zoning laws, casualty or condemnation losses, environmental risks, regulatory
limitations  on  rents, changes  in  neighborhood values,  related  party risks,
changes in the appeal of properties to tenants, increases in interest rates  and
other  real estate capital  market influences. Generally,  increases in interest
rates will increase the costs of  obtaining financing, which could directly  and
indirectly  decrease the value  of the Portfolio's  investments. The Portfolio's
share price and investment return fluctuate, and a shareholder's investment when
redeemed may be worth more or less than his original cost.
 
   
    Because it is expected that the Portfolio will invest a substantial  portion
of  its assets  in REITs, the  Portfolio will  also be subject  to certain risks
associated with  the direct  investments  of REITs.  REITs  may be  affected  by
changes in the value of their underlying properties and by defaults by borrowers
or  tenants.  Mortgage  REITs may  be  affected  by the  quality  of  the credit
extended. Furthermore,  REITs are  dependent on  specialized management  skills.
Some REITs may have limited diversification and may be subject to risks inherent
in  investments in a limited number of  properties, in a narrow geographic area,
or in  a  single property  type.  REITs depend  generally  on their  ability  to
generate cash flow to make distributions to shareholders or unitholders, and may
be  subject to defaults by borrowers  and to self-liquidations. In addition, the
performance of a REIT  may be affected  by its failure  to qualify for  tax-free
pass-through  of income under the Internal Revenue Code of 1986, as amended (the
"Code"), or  its  failure to  maintain  exemption from  registration  under  the
Investment  Company  Act  of  1940,  as amended  (the  "1940  Act").  Changes in
prevailing interest rates may inversely affect the value of the debt  securities
in which the Portfolio will invest. Changes in the value of portfolio securities
will  not necessarily affect cash income  derived from these securities but will
affect a Portfolio's net asset value.
    
 
    Because the Portfolio is a  non-diversified portfolio, the Portfolio is  not
limited  by the 1940 Act in the proportion of its assets that may be invested in
the obligations of  a single issuer.  Thus, the Portfolio  may invest a  greater
proportion  of its assets in the securities  of a smaller number of issuers and,
as a result, will  be subject to  a greater risk with  respect to its  portfolio
securities.  Any  economic,  political,  or  regulatory  developments  affecting
 
                                       11
<PAGE>
the value of the securities the Portfolio  holds could have a greater impact  on
the  total  value of  the Portfolio's  holdings than  would be  the case  if the
Portfolio's securities  were  diversified  among more  issuers.  The  Portfolio,
however,  intends to comply with the diversification requirements imposed by the
Code for  qualification  as a  regulated  investment company.  See  "Taxes"  and
"Investment Limitations."
 
                       ADDITIONAL INVESTMENT INFORMATION
 
    LOANS  OF PORTFOLIO SECURITIES.  The  Portfolio may lend their securities to
brokers, dealers, domestic and foreign banks or other financial institutions for
the purpose of increasing its net investment income. These loans must be secured
continuously by cash or equivalent collateral, or by a letter of credit at least
equal to the  market value  of the securities  loaned plus  accrued interest  or
income.  There may be a risk of delay in recovery of the securities or even loss
of rights  in  the  collateral  should  the  borrower  of  the  securities  fail
financially.  A  Portfolio  will  not enter  into  securities  loan transactions
exceeding, in the aggregate, 33  1/3% of the market  value of its total  assets.
For   more  detailed  information  about  securities  lending,  see  "Investment
Objectives and Policies" in the Statement of Additional Information.
 
    MONEY MARKET INSTRUMENTS.   The Portfolio  is permitted to  invest in  money
market   instruments,  although  the  Portfolio  intends  to  stay  invested  in
securities satisfying its primary investment objective to the extent  practical.
The  Portfolio may  make money  market investments  pending other  investment or
settlement for  liquidity, or  in adverse  market conditions.  The money  market
investments permitted for the Portfolio include obligations of the United States
Government  and  its  agencies  and  instrumentalities,  other  debt securities,
commercial paper  including  bank  obligations,  certificates  of  deposit,  and
repurchase  agreements. For more  detailed information about  these money market
investments, see "Description  of Securities  and Ratings" in  the Statement  of
Additional Information.
 
    NON-PUBLICLY   TRADED   SECURITIES,   PRIVATE   PLACEMENTS   AND  RESTRICTED
SECURITIES.  The Portfolio may invest in securities that are neither listed on a
stock  exchange  nor   traded  over-the-counter,   including  privately   placed
securities.  Such  unlisted equity  securities may  involve  a higher  degree of
business and financial risk that can  result in substantial losses. As a  result
of the absence of a public trading market for these securities, they may be less
liquid  than publicly traded securities. Although these securities may be resold
in privately negotiated transactions, the prices realized from these sales could
be less than those  originally paid by  the Portfolio or less  than what may  be
considered  the  fair value  of  such securities.  Furthermore,  companies whose
securities are not  publicly traded  may not be  subject to  the disclosure  and
other  investor  protection  requirements  which might  be  applicable  if their
securities  were  publicly  traded.  If  such  securities  are  required  to  be
registered  under the securities laws of  one or more jurisdictions before being
resold, the Portfolio may be required to bear the expenses of registration.  The
Portfolio may not invest more than 15% of its net assets in illiquid securities,
including  securities for which there is  not readily available secondary market
nor more than 10%  of its total  assets in securities  that are restricted  from
sale  to  the public  without registration  ("Restricted Securities")  under the
Securities Act of 1933,  as amended (the "1933  Act"). Nevertheless, subject  to
the  foregoing limit on illiquid securities, the  Portfolio may invest up to 15%
of its total assets  in Restricted Securities  that can be  offered and sold  to
qualified   institutional  buyers  under   Rule  144A  under   that  Act  ("144A
Securities"). The Board of Directors has adopted guidelines and delegated to the
Adviser, subject  to  the supervision  of  the  Board of  Directors,  the  daily
function  of determining and  monitoring the liquidity  of 144A Securities. 144A
Securities may  become  illiquid  if  qualified  institutional  buyers  are  not
interested in acquiring the securities.
 
                                       12
<PAGE>
    REPURCHASE  AGREEMENTS.  The Portfolio  may enter into repurchase agreements
with brokers, dealers or  banks that meet the  credit guidelines established  by
the  Fund's Board of Directors. In a  repurchase agreement, the Portfolio buys a
security from a seller  that has agreed  to repurchase it  at a mutually  agreed
upon  date and price, reflecting the interest rate effective for the term of the
agreement. The term of these agreements  is usually from overnight to one  week,
and  never exceeds  one year.  Repurchase agreements  may be  viewed as  a fully
collateralized loan  of money  by the  Portfolio to  the seller.  The  Portfolio
always  receives securities, with a market value  at least equal to the purchase
price (including accrued interest)  as collateral and  this value is  maintained
during  the term  of the  agreement. If the  seller defaults  and the collateral
value declines, the Portfolio might incur a loss. If bankruptcy proceedings  are
commenced  with  respect to  the seller,  the  Portfolio's realization  upon the
collateral may  be  delayed or  limited.  The aggregate  of  certain  repurchase
agreements  and  certain  other  investments  is  limited  as  set  forth  under
"Investment Limitations."
 
    STOCK OPTIONS,  FUTURES CONTRACTS  AND OPTIONS  IN FUTURES  CONTRACTS.   The
Portfolio  may write (i.e., sell) covered  call options on portfolio securities.
The Portfolio may write covered put options on portfolio securities. By  selling
a  covered call option, the Portfolio would  become obligated during the term of
the option to  deliver the securities  underlying the option  should the  option
holder  choose to exercise  the option before the  option's termination date. In
return for  the  call  it has  written,  the  Portfolio will  receive  from  the
purchaser  (or option holder) a premium which is the price of the option, less a
commission charged by a broker. The  Portfolio will keep the premium  regardless
of  whether  the option  is  exercised. By  selling  a covered  put  option, the
Portfolio incurs an obligation  to buy the security  underlying the option  from
the  purchaser of the put at the option's  exercise price at any time during the
option period,  at the  purchaser's  election (certain  options written  by  the
Portfolio  will be exercisable by the purchaser only on a specific date). A call
option is "covered" if the Portfolio owns the security underlying the option  it
has  written or has  an absolute or  immediate right to  acquire the security by
holding a call  option on  such security, or  maintains a  sufficient amount  of
cash, cash equivalents or liquid securities to purchase the underlying security.
Generally, a put option is "covered" if the Fund maintains cash, U.S. Government
securities  or other high grade debt obligations  equal to the exercise price of
the option, or if the  Fund holds a put option  on the same underlying  security
with a similar or higher exercise price.
 
    When  the Portfolio writes  covered call options, it  augments its income by
the premiums received and is thereby hedged to the extent of that amount against
a decline in the price of the underlying securities. The premiums received  will
offset  a  portion  of the  potential  loss  incurred by  the  Portfolio  if the
securities underlying the  options are  ultimately sold  by the  Portfolio at  a
loss.  However, during the option  period, the Portfolio has,  in return for the
premium on the option, given up  the opportunity for capital appreciation  above
the  exercise price should the market price of the underlying security increase,
but has retained the risk  of loss should the  price of the underlying  security
decline.
 
    The  Portfolio  will  write put  options  to  receive the  premiums  paid by
purchasers (when  the Adviser  wishes to  purchase the  security underlying  the
option  at  a price  lower  than its  current market  price,  in which  case the
Portfolio will write the covered put  at an exercise price reflecting the  lower
purchase price sought) and to close out a long put option position.
 
    The  Portfolio may also purchase put  options on its portfolio securities or
call options. When the Portfolio purchases  a call option it acquires the  right
to  buy a designated security at a  designated price (the "exercise price"), and
when the  Portfolio purchases  a put  option it  acquires the  right to  sell  a
designated security at the exercise price, in each case on or before a specified
date    (the   "termination   date"),   which   is   usually   not   more   than
 
                                       13
<PAGE>
nine months from the date the option is issued. The Portfolio may purchase  call
options  to close out a covered call  position or to protect against an increase
in the price of a security it anticipates purchasing. The Portfolio may purchase
put options on  securities which  it holds in  its portfolio  to protect  itself
against  decline in the  value of the  security. If the  value of the underlying
security were to fall below the exercise price of the put purchased in an amount
greater than  the premium  paid for  the option,  the Portfolio  would incur  no
additional  loss.  The Portfolio  may  also purchase  put  options to  close out
written put  positions in  a  manner similar  to  call option  closing  purchase
transactions.  There are no other limits  on the Portfolio's ability to purchase
call and put options.
 
    The Portfolio  may  enter into  futures  contracts and  options  on  futures
contracts  to  remain  fully  invested  and  to  reduce  transaction  costs. The
Portfolio  may  also  enter  into  futures  transactions  as  a  hedge   against
fluctuations  in the price of a security it holds or intends to acquire, but not
for speculation or for achieving leverage. The Portfolio may enter into  futures
contracts and options on futures contracts provided that not more than 5% of the
Portfolio's  total assets at the time of entering into the contract or option is
required as deposit to secure obligations under such contracts and options,  and
provided that not more than 20% of the Portfolio's total assets in the aggregate
is invested in futures contracts and options on futures contracts.
 
    The  Portfolio  may  purchase and  write  call  and put  options  on futures
contracts that are traded on any international exchange, traded over-the-counter
or which are synthetic options  or futures or equity  swaps, and may enter  into
closing  transactions  with respect  to such  options  to terminate  an existing
position. An option  on a  futures contract gives  the purchaser  the right  (in
return  for the premium paid) to assume a position in a futures contract (a long
position if the option is a call and a short position if the option is a put) at
a specified  exercise price  at any  time during  the term  of the  option.  The
Portfolio  will purchase  and write options  on futures  contracts for identical
purposes to  those  set forth  above  for the  purchase  of a  futures  contract
(purchase  of a call option or  sale of a put option)  and the sale of a futures
contract (purchase of a put option or sale of a call option), or to close out  a
long or short position in future contracts.
 
    Options,  futures and options on futures are derivative securities, in which
the Portfolio  may invest  for hedging  purposes,  as well  as to  remain  fully
invested  and to reduce transaction costs. Investing for the latter two purposes
may be considered  speculative. The  primary risks  associated with  the use  of
options,  futures and options  on futures are  (i) imperfect correlation between
the change in market value of the stocks held by the Portfolio and the prices of
futures and options relating to the  stocks purchased or sold by the  Portfolio;
and  (ii) possible lack of a liquid secondary  market for an option or a futures
contract and the  resulting inability to  close a futures  position which  could
have  an adverse impact on  the Portfolio's ability to  hedge. In the opinion of
the Board of Directors, the risk that the Portfolio will be unable to close  out
a  futures position or options contract will  be minimized by only entering into
futures contracts or options transactions for which there appears to be a liquid
secondary market.
 
    TEMPORARY INVESTMENTS.  For temporary  defensive purposes, when the  Adviser
determines  that market conditions warrant, the  Portfolio may invest up to 100%
of its assets  in money market  instruments consisting of  securities issued  or
guaranteed  by the United States  Government, its agencies or instrumentalities,
repurchase agreements, certificates of  deposit and bankers' acceptances  issued
by  banks or savings  and loan associations  having net assets  of at least $500
million as of the  end of their most  recent fiscal year, high-grade  commercial
paper rated, at time of purchase, in the top two categories by a national rating
agency or determined to be of
 
                                       14
<PAGE>
comparable  quality by the Adviser  at the time of  purchase and other long- and
short-term debt instruments  which are rated  A or higher  by Standard &  Poor's
Corporation  ("S&P") or Moody's Investors Service,  Inc. ("Moody's") at the time
of purchase, and may hold a portion of its assets in cash.
 
    WHEN-ISSUED AND DELAYED  DELIVERY SECURITIES.   The  Portfolio may  purchase
securities  on a  when-issued or delayed  delivery basis.  In such transactions,
instruments are bought with payment and  delivery taking place in the future  in
order  to secure what is considered to be  an advantageous yield or price at the
time of the transaction. Delivery of  and payment for these securities may  take
as  long as a month or more after  the date of the purchase commitment, but will
take place  no more  than 120  days after  the trade  date. The  Portfolio  will
maintain  with the Custodian  a separate account with  a segregated portfolio of
high-grade debt  securities  or  cash in  an  amount  at least  equal  to  these
commitments. The payment obligation and the interest rates that will be received
are  each fixed  at the  time the  Portfolio enters  into the  commitment and no
interest accrues to the  Portfolio until settlement. Thus,  it is possible  that
the  market value at  the time of settlement  could be higher  or lower than the
purchase price if  the general  level of  interest rates  has changed.  It is  a
current  policy  of  the Portfolio  not  to enter  into  when-issued commitments
exceeding, in the aggregate,  15% of the market  value of the Portfolio's  total
assets less liabilities other than the obligations created by these commitments.
 
                             INVESTMENT LIMITATIONS
 
    As a non-diversified investment company, the Portfolio is not limited by the
1940  Act in  the proportion  of its total  assets that  may be  invested in the
obligations of  a  single issuer.  Thus,  the  Portfolio may  invest  a  greater
proportion  of its total assets in the securities of a smaller number of issuers
and, as a result, will be subject to greater risk with respect to its  portfolio
securities.  However, the Portfolio  intends to comply  with the diversification
requirements imposed  by the  Internal Revenue  Code of  1986, as  amended,  for
qualification  a regulated  investment company. See  "Investment Limitations" in
the Statement of Additional Information.
 
   
    The Portfolio operates under certain investment restrictions that are deemed
fundamental limitations and may be changed only with the approval of the holders
of  a  majority   of  the  Portfolio's   outstanding  shares.  See   "Investment
Limitations"  in  the  Statement  of Additional  Information.  In  addition, the
Portfolio operates  under  certain non-fundamental  investment  limitations,  as
described  below and in  the Statement of  Additional Information. The Portfolio
may not:  (i) enter  into repurchase  agreements with  more than  seven days  to
maturity  if, as a result, more than 15%  of the market value of the Portfolio's
net assets would be invested in such repurchase agreements and other investments
for which market  quotations are not  readily available or  which are  otherwise
illiquid;  (ii)  invest  more  than  10%  of  its  total  assets  in  Restricted
Securities, except that the Portfolio may invest  up to 15% of its total  assets
in  Restricted Securities that are 144A Securities, subject to the limitation on
illiquid securities described above; (iii)  borrow money, except from banks  for
extraordinary  or emergency purposes, and then only  in amounts up to 10% of the
value of the Portfolio's total assets, taken  at cost at the time of  borrowing;
or  purchase securities  while borrowings  exceed 5%  of its  total assets; (iv)
mortgage, pledge or hypothecate  any assets except in  connection with any  such
borrowing  in amounts up to 10% of the  value of the Portfolio's total assets at
the time of borrowing; (v) invest in fixed time deposits with a duration of over
seven calendar days; or (vi) invest in  fixed timed deposits with a duration  of
from  two  business  days  to  seven  calendar days  if  more  than  10%  of the
Portfolio's total assets would be invested in these deposits.
    
 
                                       15
<PAGE>
                             MANAGEMENT OF THE FUND
 
    INVESTMENT ADVISER.  Morgan Stanley Asset Management Inc. is the  Investment
Adviser  and Administrator of the  Fund and each of  its portfolios. The Adviser
provides investment  advice and  portfolio management  services pursuant  to  an
Investment  Advisory Agreement  and, subject  to the  supervision of  the Fund's
Board of  Directors,  makes  the Portfolio's  day-to-day  investment  decisions,
arranges  for the execution of portfolio  transactions and generally manages the
Portfolio's investments. The Adviser is  entitled to receive from the  Portfolio
an  annual management fee, payable quarterly, equal to the percentage of average
daily net assets set forth in the  table below. However, the Adviser has  agreed
to  a reduction  in the fees  payable to it  and to reimburse  the Portfolio, if
necessary, if such fees would cause  the total annual operating expenses of  the
Portfolio  to exceed the  respective percentage of average  daily net assets set
forth below.
 
<TABLE>
<CAPTION>
                                                  MAXIMUM TOTAL ANNUAL
                                                        OPERATING
                                  MANAGEMENT       EXPENSES AFTER FEE
                                      FEE                WAIVERS
                                  -----------   -------------------------
          PORTFOLIO                              CLASS A         CLASS B
- ------------------------------                  ---------       ---------
<S>                               <C>           <C>             <C>
U.S. Real Estate Portfolio             0.80%       1.00%           1.25%
</TABLE>
 
    The fee payable by the Portfolio is  higher than the management fee paid  by
most  investment companies,  but the Adviser  believes the fee  is comparable to
those of investment companies with similar investment objectives.
   
    The Adviser, with  principal offices  at 1221  Avenue of  the Americas,  New
York,  New  York  10020,  conducts a  worldwide  portfolio  management business,
providing a broad  range of portfolio  management services to  customers in  the
United  States and abroad. At December 31,  1995, the Adviser, together with its
affiliated   asset   management   companies,   managed   investments    totaling
approximately  $57.4 billion, including approximately $41.9 billion under active
management and  $15.5  billion as  Named  Fiduciary or  Fiduciary  Adviser.  See
"Management of the Fund" in the Statement of Additional Information.
    
 
   
    PORTFOLIO  MANAGER. -- RUSSELL C. PLATT.  Mr. Platt joined Morgan Stanley in
1982 and  currently  is a  Principal  of the  Firm.  Russell Platt  has  primary
responsibility  for managing the real  estate securities investment business for
Morgan Stanley  Asset  Management  ("MSAM")  and  serves  as  a  member  of  the
Investment   Committee  of  The  Morgan  Stanley  Real  Estate  Fund  ("MSREF").
Previously, Mr. Platt served as  a Director of MSREF,  where he was involved  in
capital  raising, acquisitions, oversight of investments and investor relations.
MSREF is a privately held limited partnership engaged in the acquisition of real
estate assets, portfolios and real estate operating companies with gross  assets
of  approximately $3.5 billion as of December 1994. From 1991 to 1993, Mr. Platt
was  head  of  Morgan  Stanley's   Transaction  Development  Group,  which   was
responsible for identifying and structuring real estate investment opportunities
for  the Firm and its clients worldwide.  As part of these responsibilities, Mr.
Platt directed Morgan Stanley Realty's activities in Latin America and served as
U.S. liaison for Morgan Stanley Realty's Japanese real estate clients. From 1990
to 1991, Mr. Platt was based in Morgan Stanley Realty's London Office, where  he
was  responsible for  European transaction  development. Prior  to this,  he had
extensive transaction  responsibilities  involving  portfolio,  retail,  office,
hotel  and apartment  sales and  financings. Mr.  Platt graduated  from Williams
College in 1982 with a  B.A. in Economics and  received his M.B.A. from  Harvard
Business  School in 1986. Mr. Platt is a  member of the Board of Trustees of The
National Multi
    
 
                                       16
<PAGE>
   
Housing Council and The Wharton  Real Estate Center, and  a member of The  Urban
Land  Institute (International Council), the National Association of Real Estate
Investment Trusts and the Pension Real Estate Association.
    
 
   
    THEODORE R. BIGMAN.   Mr. Bigman joined Morgan  Stanley Asset Management  in
1995  as a Vice  President. Together with  Russell Platt, he  is responsible for
MSAM's real estate securities research. Prior to joining MSAM, he was a Director
at CS First Boston, where  he worked for eight years  in the Real Estate  Group.
Since  1992, Mr.  Bigman established  and managed  the REIT  effort at  CS First
Boston, including  primary responsibility  for $2.5  billion of  initial  public
offering  by real estate investment trusts. Previously, Mr. Bigman had extensive
real estate experience in a wide variety of transactions involving the financing
and sale of both individual assets and portfolios of real estate assets as  well
as  the  acquisition  and sale  of  several  real estate  companies.  Mr. Bigman
graduated from Brandeis University in 1983 with a B.A. in Economics and received
his M.B.A. from  Harvard University  in 1987.  He is  a member  of the  National
Association  of  Real  Estate  Investment Trusts  and  International  Council of
Shopping Centers.
    
 
    ADMINISTRATOR.   The  Adviser also  provides  the Fund  with  administrative
services  pursuant to an  Administration Agreement. The  services provided under
the Administration Agreement are subject to the supervision of the Officers  and
the  Board of  Directors of  the Fund  and include  day-to-day administration of
matters related  to the  corporate existence  of the  Fund, maintenance  of  its
records, preparation of reports, supervision of the Fund's arrangements with its
custodian,  and  assistance  in  the  preparation  of  the  Fund's  registration
statements under  Federal  and State  laws.  The Administration  Agreement  also
provides  that the Administrator,  through its agents, will  provide to the Fund
dividend disbursing  and transfer  agent services.  For its  services under  the
Administration  Agreement, the Fund pays  the Adviser a monthly  fee which on an
annual basis equals 0.15% of the average daily net assets of the Portfolio.
 
   
    Under an agreement between  the Adviser and The  Chase Manhattan Bank,  N.A.
("Chase"),  Chase provides  certain administrative  services to  the Fund.  In a
merger completed on September 1, 1995, Chase succeeded to all of the rights  and
obligations  under the U.S.  Trust Administration Agreement  between the Adviser
and the United  States Trust  Company of New  York ("U.S.  Trust"), pursuant  to
which  U.S. Trust had  agreed to provide certain  administrative services to the
Fund.  Pursuant  to  a  delegation  clause  in  the  U.S.  Trust  Administration
Agreement,  U.S. Trust  delegated its  administrative responsibilities  to Chase
Global Funds Services Company ("CGFSC"), formerly known as Mutual Funds  Service
Company,  which after the  merger with Chase  is a subsidiary  of Chase and will
continue to provide  certain administrative  services to the  Fund. The  Adviser
supervises  and  monitors such  administrative services  provided by  CGFSC. The
services  provided  under  the  Administration  Agreement  and  the  U.S.  Trust
Administration  Agreement are  also subject to  the supervision of  the Board of
Directors of the  Fund. The  Board of  Directors of  the Fund  has approved  the
provision  of services described above  pursuant to the Administration Agreement
and the U.S. Trust Administration Agreement,  as being in the best interests  of
the  Fund. CGFSC's business address is  73 Tremont Street, Boston, Massachusetts
02108-3913. For additional information regarding the Administration Agreement or
the U.S. Trust  Administration Agreement, see  "Management of the  Fund" in  the
Statement of Additional Information.
    
 
    DIRECTORS  AND OFFICERS.  Pursuant to  the Fund's Articles of Incorporation,
the Board of Directors  decides upon matters of  general policy and reviews  the
actions  of the Fund's  Adviser, Administrator and  Distributor. The Officers of
the Fund conduct and supervise its daily business operations.
 
                                       17
<PAGE>
    DISTRIBUTOR.   Morgan  Stanley serves  as the  exclusive Distributor  of the
shares of  the Fund.  Under its  Distribution Agreement  with the  Fund,  Morgan
Stanley sells shares of the Portfolio upon the terms and at the current offering
price  described in this Prospectus. Morgan Stanley is not obligated to sell any
certain number of shares of the Portfolio.
 
    The Portfolio currently offers  only the classes of  shares offered by  this
Prospectus.  The Portfolio may in the future offer one or more classes of shares
with features, distribution expenses or  other expenses that are different  from
those of the classes currently offered.
 
    The  Fund has  adopted a Plan  of Distribution  with respect to  the Class B
shares pursuant to Rule 12b-1 under the  1940 Act (the "Plan"). Under the  Plan,
the  Distributor is entitled  to receive from the  Portfolio a distribution fee,
which is accrued  daily and  paid quarterly,  of 0.25%  of the  Class B  shares'
average  daily net  assets on  an annualized  basis. The  Distributor expects to
reallocate most of its  fee to its  investment representatives. The  Distributor
may,  in its discretion, voluntarily waive from  time to time all or any portion
of its distribution fee and each of  the Distributor and the Adviser is free  to
make  additional payments  out of  its own  assets to  promote the  sale of Fund
shares,  including   payments  that   compensate  financial   institutions   for
distribution services or shareholder services.
 
    The  Plan is designed to compensate the Distributor for its services, not to
reimburse the Distributor for its expenses,  and the Distributor may retain  any
portion  of the fee that it does not expend in fulfillment of its obligations to
the Fund.
 
    EXPENSES.  The Portfolio  is responsible for payment  of certain other  fees
and  expenses  (including legal  fees,  accountants' fees,  custodial  fees, and
printing and mailing  costs) specified  in the  Administration and  Distribution
Agreements.
 
                               PURCHASE OF SHARES
 
    Class  A and Class B shares of the Portfolio may be purchased, without sales
commission, at the net  asset value per share  next determined after receipt  of
the purchase order by the Portfolio. See "Valuation of Shares."
 
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
 
    For  an account for the Portfolio opened on or after January 2, 1996 (a "New
Account"), the minimum initial investment and minimum account size are  $500,000
for  Class  A shares  and  $100,000 for  Class  B shares.  Managed  Accounts may
purchase Class A shares without being subject to any minimum initial  investment
or  minimum account size  requirements for a Portfolio  account. Officers of the
Adviser and its affiliates are subject to the minimums for a Portfolio  account,
except  they may purchase Class B shares subject to a minimum initial investment
and minimum account size of $5,000 for a Portfolio account.
 
    If the value of a New Account containing Class A shares falls below $500,000
(but remains at  or above  $100,000) because of  shareholder redemption(s),  the
Fund  will  notify  the shareholder,  and  if  the account  value  remains below
$500,000 (but remains at or above $100,000) for a continuous 60-day period,  the
Class  A shares  in such  account will  convert to  Class B  shares and  will be
subject to the  distribution fee and  other features applicable  to the Class  B
shares.  The Fund, however,  will not convert  Class A shares  to Class B shares
based solely upon  changes in  the market  that reduce  the net  asset value  of
shares.  Under  current tax  law, conversions  between share  classes are  not a
taxable event to the shareholder.
 
                                       18
<PAGE>
    Shares in a Portfolio account opened  prior to January 2, 1996 (a  "Pre-1996
Account")  were  designated Class  A  shares on  January  2, 1996.  Shares  in a
Pre-1996 Account  with  a  value  of  $100,000 or  more  on  March  1,  1996  (a
"Grandfathered  Class A  Account") remain Class  A shares  regardless of account
size thereafter. Except for  shares in a Managed  Account, shares in a  Pre-1996
Account  with a value of  less than $100,000 on  March 1, 1996 (a "Grandfathered
Class B account")  convert to  Class B shares  on March  1, 1996.  Grandfathered
Class A Accounts and Managed Accounts are not subject to conversion from Class A
shares to Class B shares.
   
    Investors  may also invest in the Fund  by purchasing shares through a trust
department, broker, dealer, agent, financial planner, financial services firm or
investment adviser.  An  investor  may  be  charged  an  additional  service  or
transaction fee by that institution. The minimum investment levels may be waived
at  the discretion  of the  Adviser for (i)  certain employees  and customers of
Morgan Stanley  or  its  affiliates  and  certain  trust  departments,  brokers,
dealers,  agents, financial  planners, financial  services firms,  or investment
advisers that  have  entered  into  an agreement  with  Morgan  Stanley  or  its
affiliates;  and (ii) retirement and deferred compensation plans and trusts used
to fund such  plans, including,  but not limited  to, those  defined in  Section
401(a),  403(b) or  457 of the  Internal Revenue  Code of 1986,  as amended, and
"rabbi trusts".  The  Fund  reserves  the  right  to  modify  or  terminate  the
conversion  features of  the shares  as stated above  at any  time upon 60-days'
notice to shareholders.
    
 
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
 
    If the value of  a New Account falls  below $100,000 because of  shareholder
redemption(s),  the Fund will  notify the shareholder, and  if the account value
remains below  $100,000 for  a  continuous 60-day  period,  the shares  in  such
account  are subject to redemption  by the Fund and,  if redeemed, the net asset
value of  such  shares will  be  promptly paid  to  the shareholder.  The  Fund,
however,  will not redeem  shares based solely  upon changes in  the market that
reduce the net asset value of shares.
 
    For purposes of redemptions by the Fund, the foregoing minimum account  size
requirements  do not  apply to  New Accounts containing  Class B  shares held by
officers of the Adviser or its affiliates. However, if the value of such account
held by an officer of the Adviser  or its affiliates falls below $5,000  because
of  shareholder redemption(s), the Fund will  notify the shareholder, and if the
account value remains below $5,000 for a continuous 60-day period, the shares in
such account are subject  to redemption by  the Fund and,  if redeemed, the  net
asset value of such shares will be promptly paid to the shareholder.
 
    Grandfathered  Class A Accounts, Grandfathered  Class B Accounts and Managed
Accounts are not subject to involuntary redemption.
 
    The  Fund  reserves  the  right  to  modify  or  terminate  the  involuntary
redemption  features of  the shares  as stated above  at any  time upon 60-days'
notice to shareholders.
 
CONVERSION FROM CLASS B TO CLASS A SHARES
 
    If the value of Class B shares in a Portfolio account increases, whether due
to shareholder share  purchases or  market activity,  to $500,000  or more,  the
Class  B shares  will convert  to Class  A shares.  Under current  tax law, such
conversion is not a taxable event  to the shareholder. Class A shares  converted
from  Class B shares are  subject to the same  minimum account size requirements
that are applicable to New Accounts containing Class A shares, as stated  above.
The  Fund reserves the right  to modify or terminate  this conversion feature at
any time upon 60-days' notice to shareholders.
 
                                       19
<PAGE>
INITIAL PURCHASES DIRECTLY FROM THE FUND
 
    The Fund's determination of an investor's eligibility to purchase shares  of
a  given class will  take precedence over  the investor's selection  of a class.
Assuming the investor is eligible for the  class, the Fund will select the  most
favorable class for the investor, if the investor has not done so.
 
1) BY  CHECK.   An account may  be opened  by completing and  signing an Account
   Registration Form and mailing it, together with a check ($500,000 minimum for
   Class A  shares of  the Portfolio  and $100,000  for Class  B shares  of  the
   Portfolio,  with certain exceptions  for Morgan Stanley  employees and select
   customers) payable to "Morgan Stanley  Institutional Fund, Inc. -- U.S.  Real
   Estate Portfolio", to:
 
      Morgan Stanley Institutional Fund, Inc.
      P.O. Box 2798
      Boston, Massachusetts 02208-2798
 
     Payment will  be accepted only  in U.S. dollars,  unless prior approval for
  payment by other currencies is given by  the Fund. The class(es) of shares  of
  the Portfolio to be purchased should be designated on the Account Registration
  Form.  For purchases  by check, the  Fund is ordinarily  credited with Federal
  Funds within  one business  day. Thus,  your purchase  of shares  by check  is
  ordinarily  credited to your account  at the net asset  value per share of the
  Portfolio determined on the next business day after receipt.
 
2) BY FEDERAL  FUNDS WIRE.   Purchases  may be  made by  having your  bank  wire
   Federal  Funds to the Fund's bank account.  In order to ensure prompt receipt
   of your Federal Funds Wire, it is important that you follow these steps:
 
A.  Telephone  the Fund  (toll free: 1-800-548-7786)  and provide  us with  your
    name,  address,  telephone  number, Social  Security  or  Tax Identification
    Number, the  portfolio(s) selected,  the class  selected, the  amount  being
    wired,  and by  which bank.  We will  then provide  you with  a Fund account
    number. (Investors with existing accounts should also notify the Fund  prior
    to wiring funds.)
 
B.    Instruct  your  bank to  wire  the  specified amount  to  the  Fund's Wire
    Concentration Bank Account (be  sure to have your  bank include the name  of
    the  portfolio(s)  selected,  the  class selected,  and  the  account number
    assigned to you) as follows:
 
   
    Chase Manhattan Bank, N.A.
    One Manhattan Plaza
    New York, NY 10081-1000
    ABA #021000021
    DDA #910-2-733293
    Attn: Morgan Stanley Institutional Fund, Inc.
    Ref: (Portfolio name, your account number, your account name)
    
 
    Please call the Fund at 1-800-548-7786 prior to wiring funds.
 
C.  Complete and sign the Account  Registration Form and mail it to the  address
    shown thereon.
 
                                       20
<PAGE>
  Purchase  orders for shares of  the Portfolio which are  received prior to the
  regular close of the NYSE (currently 4:00 p.m. Eastern Time) will be  executed
  at  the price computed  on the date of  receipt as long  as the Transfer Agent
  receives payment by check or  in Federal Funds prior  to the regular close  of
  the NYSE on such day.
 
  Federal Funds purchase orders will be accepted only on a day on which the Fund
  and Chase (the "Custodian Bank") are open for business. Your bank may charge a
  service fee for wiring Federal Funds.
 
3) BY  BANK WIRE.   The  same procedure outlined  under "By  Federal Funds Wire"
   above must be  followed in  purchasing shares  by bank  wire. However,  money
   transferred  by bank wire may or may  not be converted into Federal Funds the
   same day, depending on the time the  money is received and the bank  handling
   the wire. Prior to such conversion, an investor's money will not be invested.
   Your bank may charge a service fee for wiring funds.
 
ADDITIONAL INVESTMENTS
 
    You  may  add to  your account  at any  time (minimum  additional investment
$1,000  except  for  automatic  reinvestment  of  dividends  and  capital  gains
distributions for which there are no minimums) by purchasing shares at net asset
value  by mailing a check to the  Fund (payable to "Morgan Stanley Institutional
Fund, Inc. --  U.S. Real Estate  Portfolio" at  the above address  or by  wiring
monies  to the Custodian Bank as outlined  above. It is very important that your
account name, the  portfolio name  and the class  selected be  specified in  the
letter  or wire to assure  proper crediting to your  account. In order to insure
that your wire orders are invested promptly, you are requested to notify one  of
the  Fund's representatives (toll free: 1-800-548-7786)  prior to the wire date.
Additional investments will be applied to purchase additional shares in the same
class held by a shareholder in a Portfolio account.
 
OTHER PURCHASE INFORMATION
 
    The purchase price of the Class A and Class B shares of the Portfolio is the
net asset value next determined after  the order is received. See "Valuation  of
Shares."  An order received  prior to the  close of the  New York Stock Exchange
("NYSE"), which is  currently 4:00 p.m.  Eastern Time, will  be executed at  the
price  computed on the date of receipt; an order received after the close of the
NYSE will be executed at the price computed on the next day the NYSE is open  as
long  as the Transfer Agent receives payment  by check or in Federal Funds prior
to the regular close of the NYSE on such day.
 
    Although the legal rights of Class A  and Class B shares will be  identical,
the  different expenses borne by  each class will result  in different net asset
values and dividends. The net  asset value of Class  B shares will generally  be
lower than the net asset value of Class A shares as a result of the distribution
expense  charged to Class B shares. It  is expected, however, that the net asset
value per share of the two classes  will tend to converge immediately after  the
recording  of dividends  which will  differ by  approximately the  amount of the
distribution expense accrual differential between the classes.
 
    In the interest  of economy and  convenience, and because  of the  operating
procedures  of the Fund, certificates representing  shares of the Portfolio will
not be issued. All shares  purchased are confirmed to  you and credited to  your
account  on the Fund's books  maintained by the Adviser  or its agents. You will
have  the  same  rights  and  ownership  with  respect  to  such  shares  as  if
certificates had been issued.
 
                                       21
<PAGE>
    To  ensure that checks are collected by the Fund, withdrawals of investments
made by check  are not presently  permitted until payment  for the purchase  has
been  received,  which may  take up  to eight  business days  after the  date of
purchase. As a condition  of this offering,  if a purchase  is cancelled due  to
nonpayment or because your check does not clear, you will be responsible for any
loss  the Fund or its  agents incur. If you are  already a shareholder, the Fund
may redeem shares from your account(s) to  reimburse the Fund or its agents  for
any  loss. In addition, you  may be prohibited or  restricted from making future
investments in the Fund.
 
    Investors may  also invest  in the  Fund by  purchasing shares  through  the
Distributor.   See  "Purchase  of   Shares"  in  the   Statement  of  Additional
Information.
 
EXCESSIVE TRADING
 
    Frequent  trades  involving  either   substantial  portfolio  assets  or   a
substantial  portion of your  account or accounts controlled  by you can disrupt
management of a portfolio and raise its expenses. Consequently, in the  interest
of  all the stockholders  of the Portfolio and  the Portfolio's performance, the
Fund may in its discretion bar  a stockholder that engages in excessive  trading
of  shares of any class  of a portfolio from further  purchases of shares of the
Fund for an indefinite period. The  Fund considers excessive trading to be  more
than  one purchase and sale involving shares of the same class of a portfolio of
the Fund  within  any  120-day  period. As  an  example,  exchanging  shares  of
portfolios of the Fund as follows amounts to excessive trading: exchanging Class
A shares of Portfolio A for Class A shares of Portfolio B, then exchanging Class
A  shares of Portfolio B for Class A  shares of Portfolio C and again exchanging
Class A shares of Portfolio C for Class A shares of Portfolio B within a 120-day
period. Two  types  of transactions  are  exempt from  these  excessive  trading
restrictions:  (1) trades exclusively  between money market  portfolios; and (2)
trades done  in  connection  with  an asset  allocation  service,  such  as  TFM
Accounts, managed or advised by MSAM and/or any of its affiliates.
 
                              REDEMPTION OF SHARES
 
    You  may  withdraw all  or  any portion  of the  amount  in your  account by
redeeming shares at any time. Please note  that purchases made by check are  not
permitted to be redeemed until payment of the purchase price has been collected,
which  may take up to  eight business days after  purchase. The Fund will redeem
Class A shares or  Class B shares  of the Portfolio at  the next determined  net
asset  value of shares of  the applicable class. On days  that both the NYSE and
the Custodian Bank are open for business,  the net asset value per share of  the
Portfolio is determined at the close of trading of the NYSE (currently 4:00 p.m.
Eastern  time). Shares of the Portfolio may be redeemed by mail or telephone. No
charge is made  for redemption.  Any redemption  may be  more or  less than  the
purchase  price of  your shares  depending on,  among other  factors, the market
value of the investment securities held by the Portfolio.
 
BY MAIL
 
    The Portfolio will redeem its  Class A shares or Class  B shares at the  net
asset  value determined on the  date the request is  received, if the request is
received in "good  order" before  the regular close  of the  NYSE. Your  request
should  be addressed to Morgan Stanley  Institutional Fund, Inc., P.O. Box 2798,
Boston, Massachusetts 02208-2798,  except that deliveries  by overnight  courier
should be addressed to Morgan Stanley Institutional Fund, Inc., c/o Chase Global
Funds Services Company, 73 Tremont Street, Boston, Massachusetts 02108-3913.
 
                                       22
<PAGE>
    "Good  order"  means that  the  request to  redeem  shares must  include the
following documentation:
 
        (a)  A letter of instruction or a stock assignment specifying the number
    of shares or dollar amount to  be redeemed, signed by all registered  owners
    of the shares in the exact names in which they are registered;
 
        (b)   Any  required   signature  guarantees   (see  "Further  Redemption
    Information" below); and
 
        (c)   Other supporting  legal documents,  if required,  in the  case  of
    estates,  trusts, guardianships,  custodianships, corporations,  pension and
    profit sharing plans and other organizations.
 
    Shareholders who are uncertain of requirements for redemption should consult
with a Morgan Stanley Institutional Fund representative.
 
BY TELEPHONE
 
    Provided you have previously elected the Telephone Redemption Option on  the
Account  Registration  Form, you  can  request a  redemption  of your  shares by
calling the Fund  and requesting  the redemption proceeds  be mailed  to you  or
wired  to your bank.  Please contact one of  Morgan Stanley Institutional Fund's
representatives for further details. In times of drastic market conditions,  the
telephone  redemption option  may be difficult  to implement.  If you experience
difficulty in making a telephone redemption, your request may be made by mail or
overnight courier and will be implemented at the net asset value next determined
after it is received. Redemption requests sent to the Fund through express  mail
must  be mailed  to the  address of the  Dividend Disbursing  and Transfer Agent
listed under "General Information". The Fund and the Fund's transfer agent  (the
"Transfer  Agent")  will  employ  reasonable  procedures  to  confirm  that  the
instructions communicated  by telephone  are genuine.  These procedures  include
requiring the investor to provide certain personal identification information at
the  time an account is opened and prior to effecting each transaction requested
by telephone. In addition, all  telephone transaction requests will be  recorded
and   investors  may  be  required  to  provide  additional  telecopied  written
instructions regarding transaction requests. Neither  the Fund nor the  Transfer
Agent will be responsible for any loss, liability, cost or expense for following
instructions received by telephone that either of them reasonably believes to be
genuine.
 
    To  change the commercial  bank or account  designated to receive redemption
proceeds, a written  request must  be sent  to the  Fund at  the address  above.
Requests  to change the bank  or account must be  signed by each shareholder and
each signature must be guaranteed.
 
FURTHER REDEMPTION INFORMATION
 
    Normally the  Fund will  make payment  for all  shares redeemed  within  one
business  day of receipt  of the request, but  in no event  will payment be made
more than  seven days  after receipt  of  a redemption  request in  good  order.
However,  payments to investors  redeeming shares which  were purchased by check
will not be made until  payment for the purchase  has been collected, which  may
take up to eight days after the date of purchase. The Fund may suspend the right
of  redemption or postpone the date upon which redemptions are effected at times
when the NYSE is closed, or  under any emergency circumstances as determined  by
the Securities and Exchange Commission (the "Commission").
 
    If  the Board of  Directors determines that  it would be  detrimental to the
best interests of the  remaining shareholders of the  Portfolio to make  payment
wholly  or partly in cash, the Fund may  pay the redemption proceeds in whole or
in part by a distribution in-kind of securities held by the Portfolio in lieu of
cash in
 
                                       23
<PAGE>
conformity with applicable rules  of the Commission. Distributions-in-kind  will
be  made in readily marketable securities. Investors may incur brokerage charges
on the sale of portfolio securities so received in payment of redemptions.
 
    To protect  your account,  the Fund  and its  agents from  fraud,  signature
guarantees  are required for  certain redemptions to verify  the identity of the
person who has  authorized a redemption  from your account.  Please contact  the
Fund  for further  information. See "Redemption  of Shares" in  the Statement of
Additional Information.
 
                              SHAREHOLDER SERVICES
 
EXCHANGE FEATURES
 
    You may exchange  shares that you  own in  the Portfolio for  shares of  any
other  available  portfolio of  the Fund  (other  than the  International Equity
Portfolio, which is  closed to  new investors). In  exchanging for  shares of  a
portfolio  with more  than one  class, the  class of  shares you  receive in the
exchange will be determined in the same  manner as any other purchase of  shares
and  will not  be based  on the  class of  shares surrendered  for the exchange.
Consequently, the same minimum initial  investment and minimum account size  for
determining  the  class  of shares  received  in  the exchange  will  apply. See
"Purchase of  Shares." Shares  of the  portfolios may  be exchanged  by mail  or
telephone.  The privilege to exchange shares  by telephone is automatic and made
available without shareholder election. Before you make an exchange, you  should
read  the prospectus of the portfolio(s) in which you seek to invest. Because an
exchange transaction  is treated  as a  redemption followed  by a  purchase,  an
exchange  would be considered  a taxable event for  shareholders subject to tax.
The exchange privilege  is only available  with respect to  portfolios that  are
registered  for  sale  in  a  shareholder's  state  of  residence.  The exchange
privilege may be modified or  terminated by the Fund  at any time upon  60-days'
notice to shareholders.
 
BY MAIL
 
    In  order to  exchange shares  by mail, you  should include  in the exchange
request the name, class of shares and account number of your current  portfolio,
the  names of the portfolio(s) and class(es)  of shares into which you intend to
exchange shares, and the signatures of all registered account holders. Send  the
exchange  request to Morgan  Stanley Institutional Fund,  P.O. Box 2798, Boston,
Massachusetts 02208-2798.
 
BY TELEPHONE
 
    When exchanging shares by  telephone, have ready the  name, class of  shares
and  account number of the current Portfolio,  the names of the portfolio(s) and
class(es) of  shares into  which  you intend  to  exchange shares,  your  Social
Security  number  or Tax  I.D. number,  and your  account address.  Requests for
telephone exchanges received prior to 4:00 p.m. (Eastern time) are processed  at
the close of business that same day based on the net asset value of the class of
the  Portfolios involved in the exchange of the shares at the close of business.
Requests received after 4:00 p.m. (Eastern time) are processed the next business
day based on the  net asset value  determined at the close  of business on  such
day. For additional information regarding responsibility for the authenticity of
telephoned instructions, see "Redemption of Shares -- By Telephone" above.
 
TRANSFER OF REGISTRATION
 
    You  may transfer  the registration  of any of  your Fund  shares to another
person by writing  to Morgan Stanley  Institutional Fund, Inc.,  P.O. Box  2798,
Boston,   Massachusetts  02208-2798.  As   in  the  case   of  redemptions,  the
 
                                       24
<PAGE>
written request must be received in good order before any transfer can be  made.
Transferring  the  registration of  shares may  affect  the eligibility  of your
account for  a  given  class  of  the  Portfolio's  shares  and  may  result  in
involuntary  conversion or redemption  of your shares.  See "Purchase of Shares"
above.
 
                              VALUATION OF SHARES
 
    The net asset  value per  share of  a class of  shares of  the Portfolio  is
determined by dividing the total market value of the Portfolio's investments and
other  assets attributable to  such class, less  any liabilities attributable to
such class, by  the total  number of  outstanding shares  of such  class of  the
Portfolio.  Net  asset value  is  calculated separately  for  each class  of the
Portfolio. Net asset value per share is  determined as of the close of the  NYSE
on  each day  that the NYSE  is open  for business. Price  information on listed
securities is taken from  the exchange where the  security is primarily  traded.
Securities  listed on a U.S. securities exchange for which market quotations are
available are valued at the last quoted  sale price on the day the valuation  is
made. Securities listed on a foreign exchange are valued at their closing price.
Unlisted  securities and listed securities not  traded on the valuation date for
which market quotations are not readily available are valued at a price that  is
considered  to best  represent fair value  within a  range not in  excess of the
current asked price nor  less than the  current bid price.  The current bid  and
asked  prices are determined  based on the  bid and asked  prices quoted on such
valuation date by reputable brokers.
 
    Bonds and other fixed income securities are valued according to the broadest
and most representative  market, which will  ordinarily be the  over-the-counter
market.  Net asset value includes interest  on fixed income securities, which is
accrued daily.  In addition,  bonds and  other fixed  income securities  may  be
valued on the basis of prices provided by a pricing service when such prices are
believed  to  reflect  the fair  market  value  of such  securities.  The prices
provided by a pricing service are determined without regard to bid or last  sale
prices,  but take into  account institutional-size trading  in similar groups of
securities and any developments related  to the specific securities.  Securities
not  priced in this manner are valued at the most recently quoted sale price, or
when securities exchange valuations are used, at the latest quoted bid price  on
the  day of valuation. If there is no  such reported sale, the latest quoted bid
price will be used. Securities purchased with remaining maturities of 60 days or
less are valued at amortized cost, if it approximates market value. In the event
that amortized  cost  does  not  approximate  market  value,  market  prices  as
determined above will be used.
 
    The value of other assets and securities for which no quotations are readily
available  (including  restricted  and unlisted  foreign  securities)  and those
securities for which it is inappropriate to determine prices in accordance  with
the  above-stated procedures  are determined in  good faith at  fair value using
methods determined by the  Board of Directors. For  purposes of calculating  net
asset value per share, all assets and liabilities initially expressed in foreign
currencies  will  be translated  into  U.S. dollars  at  the bid  price  of such
currencies against the U.S. dollar last quoted by any major bank.
 
    Although the legal rights of Class A  and Class B shares will be  identical,
the  different expenses borne by  each class will result  in different net asset
values and dividends for the class.  Dividends will differ by approximately  the
amount  of the distribution expense accrual  differential among the classes. The
net asset value of  Class B shares  will generally be lower  than the net  asset
value  of the Class A shares as a  result of the distribution expense charged to
Class B shares.
 
                                       25
<PAGE>
                            PERFORMANCE INFORMATION
 
    The Fund may from time to time advertise total return for each class of  the
Portfolio.  THESE FIGURES ARE BASED ON  HISTORICAL EARNINGS AND ARE NOT INTENDED
TO INDICATE FUTURE PERFORMANCE. The "total return" shows what an investment in a
class of the Portfolio would have earned  over a specified period of time  (such
as one, five or ten years), assuming that all distributions and dividends by the
Portfolio were reinvested in the same class on the reinvestment dates during the
period.  Total return  does not  take into account  any federal  or state income
taxes that may be payable on dividends and distributions or upon redemption. The
Fund may  also include  comparative performance  information in  advertising  or
marketing   the  Portfolio's  shares,  including  data  from  Lipper  Analytical
Services,  Inc.,  other  industry  publications,  business  periodicals,  rating
services and market indices.
 
    The  performance figures  for Class  B shares  will generally  be lower than
those for Class  A shares because  of the  distribution fee charged  to Class  B
shares.
 
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
 
    All  income dividends and capital gains  distributions for a class of shares
will be automatically reinvested in additional shares of such class at net asset
value, except that,  upon written  notice to  the Fund  or by  checking off  the
appropriate  box in the Distribution Option  Section on the Account Registration
Form, a shareholder  may elect  to receive  income dividends  and capital  gains
distributions in cash.
 
    The  Portfolio expects to distribute substantially all of its net investment
income in the form of quarterly  dividends beginning with a distribution at  the
end of the first calendar quarter of 1996. Net realized gains for the Portfolio,
if  any, after reduction for any tax loss carryforwards will also be distributed
annually. Confirmations of the purchase of  shares of the Portfolio through  the
automatic  reinvestment of income dividends and capital gains distributions will
be provided, pursuant  to Rule 10b-10(b)  under the Securities  Exchange Act  of
1934,  as amended, on the next  monthly client statement following such purchase
of shares. Consequently, confirmations of such purchases will not be provided at
the time of completion of such purchases, as might otherwise be required by Rule
10b-10.
 
    Undistributed net  investment  income is  included  in the  Portfolio's  net
assets  for the purpose of calculating net  asset value per share. Therefore, on
the "ex-dividend" date,  the net  asset value  per share  excludes the  dividend
(i.e.,  is reduced  by the  per share  amount of  the dividend).  Dividends paid
shortly after the purchase of shares by an investor, although in effect a return
of capital, are taxable to shareholders subject to income tax.
 
    Because of  the  distribution  fee  and  any  other  expenses  that  may  be
attributable  to the  Class B  shares, the  net income  attributable to  and the
dividends payable  on  Class  B  shares  will  be  lower  than  the  net  income
attributable  to and the dividends  payable on Class A  shares. As a result, the
net asset value per share of the classes of the Portfolio will differ at  times.
Expenses of the Portfolio allocated to a particular class of shares thereof will
be borne on a pro rata basis by each outstanding share of that class.
 
                                     TAXES
 
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
 
                                       26
<PAGE>
    No  attempt has been made to present  a detailed explanation of the federal,
state, or  local income  tax treatment  of the  Portfolio or  its  shareholders.
Accordingly,  shareholders  are urged  to consult  their tax  advisers regarding
specific questions as to federal, state and local income taxes.
 
    The Portfolio  is  treated as  a  separate  entity for  federal  income  tax
purposes  and  is not  combined  with the  Fund's  other portfolios.  It  is the
Portfolio's intent to continue to qualify for the special tax treatment afforded
regulated investment  companies under  Subchapter M  of the  Code, so  that  the
Portfolio will continue to be relieved of federal income tax on that part of its
net investment income and net capital gain that is distributed to shareholders.
 
   
    The  Portfolio distributes  substantially all  of its  net investment income
(including, for this purpose, the excess of net short-term capital gain over net
long-term capital  loss) to  shareholders. Dividends  from the  Portfolio's  net
investment  income  are  taxable  to shareholders  as  ordinary  income, whether
received in cash or in additional shares. The Portfolio will report annually  to
its  shareholders the  amount of  dividend income  qualifying for  the corporate
dividend received deduction.
    
 
    Distributions of net capital gain (the excess of net long-term capital  gain
over  net  short-term capital  loss) are  taxable  to shareholders  as long-term
capital gain, regardless of  how long shareholders have  held their shares.  The
Portfolio  sends reports annually to its  shareholders of the federal income tax
status of all distributions made during the preceding year.
 
    The  Portfolio   intends  to   make  sufficient   distributions  or   deemed
distributions  of its ordinary income and capital gain net income (the excess of
short-term and long-term  capital gains  over short-term  and long-term  capital
losses)  prior to the end  of each calendar year  to avoid liability for federal
excise tax.
 
    Dividends and  other distributions  declared by  the Portfolio  in  October,
November or December of any year and payable to shareholders of record on a date
in  such month will be deemed to have been paid by the Portfolio and received by
the shareholders on December 31  of that year if  the distributions are paid  by
the Portfolio at any time during the following January.
 
   
    The  sale, redemption or  exchange of shares  may result in  taxable gain or
loss to the selling, exchanging or redeeming shareholder, depending upon whether
the fair market value of the sale, exchange or redemption proceeds exceeds or is
less than the shareholder's  adjusted basis in the  redeemed, exchanged or  sold
shares.  Any such taxable  gain or loss  generally will be  treated as long-term
capital gain or loss  if the shares have  been held for more  than one year  and
otherwise  generally  will be  treated as  short-term capital  gain or  loss. If
capital gain distributions have been made  with respect to shares that are  sold
at  a loss after  being held for six  months or less, however,  then the loss is
treated as  a  long-term  capital  loss  to  the  extent  of  the  capital  gain
distributions.
    
 
    The  conversion of Class A shares to Class  B shares should not be a taxable
event to the shareholder.
 
    Investment income  received by  the Portfolio  from sources  within  foreign
countries  may be subject to foreign income taxes withheld at the source. To the
extent that the Portfolio  is liable for foreign  income taxes so withheld,  the
Portfolio  intends to operate so as to meet the requirements of the Code to pass
through to the shareholders credit for  foreign income taxes paid. Although  the
Portfolio  intends to  meet Code  requirements to  pass through  credit for such
taxes, there can be no assurance that the Portfolio will be able to do so.
 
                                       27
<PAGE>
    Shareholders are urged  to consult  with their tax  advisers concerning  the
application  of state  and local income  taxes to investments  in the Portfolio,
which may differ from the federal income tax consequences described above.
 
    THE  TAX  DISCUSSION  SET  FORTH  ABOVE  IS  INCLUDED  HEREIN  FOR   GENERAL
INFORMATION  ONLY. PROSPECTIVE INVESTORS  SHOULD CONSULT THEIR  OWN TAX ADVISERS
WITH RESPECT TO THE TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN A PORTFOLIO.
 
                             PORTFOLIO TRANSACTIONS
 
    The Investment  Advisory  Agreement authorizes  the  Adviser to  select  the
brokers  or  dealers that  will execute  the purchases  and sales  of investment
securities for the Portfolio and directs the Adviser to use its best efforts  to
obtain the best available price and most favorable execution with respect to all
transactions  for  the Portfolio.  The Fund  has authorized  the Adviser  to pay
higher commissions in recognition of brokerage services which, in the opinion of
the Adviser, are necessary for the achievement of better execution, provided the
Adviser believes this to be in the best interest of the Fund.
 
    Since shares of the Portfolio are not marketed through intermediary  brokers
or  dealers, it is  not the Fund's  practice to allocate  brokerage or principal
business on the basis of sales of  shares which may be made through such  firms.
However,  the Adviser may  place portfolio orders  with qualified broker-dealers
who recommend the Portfolio or  who act as agents in  the purchase of shares  of
the Fund's portfolios for their clients.
 
    In  purchasing and  selling securities for  the Portfolio, it  is the Fund's
policy to seek to obtain quality execution at the most favorable prices  through
responsible   broker-dealers.  In   selecting  broker-dealers   to  execute  the
securities transactions for the Portfolio,  consideration will be given to  such
factors  as the price of the security, the  rate of the commission, the size and
difficulty of  the  order,  the  reliability,  integrity,  financial  condition,
general  execution and operational capabilities of competing broker-dealers, and
the brokerage  and  research services  which  they  provide to  the  Fund.  Some
securities  considered for investment  by the Portfolio  may also be appropriate
for other clients served by the Adviser.  If the purchase or sale of  securities
consistent  with the  investment policies  of the Portfolio  and one  or more of
these other clients served  by the Adviser  is considered at  or about the  same
time,  transactions in such securities will be allocated among the Portfolio and
such other  clients in  a manner  deemed  fair and  reasonable by  the  Adviser.
Although  there is  no specified formula  for allocating  such transactions, the
various allocation  methods  used  by  the Adviser,  and  the  results  of  such
allocations, are subject to periodic review by the Fund's Board of Directors.
 
    Subject to the overriding objective of obtaining the best possible execution
of  orders,  the Adviser  may allocate  a portion  of the  Portfolio's brokerage
transactions to Morgan Stanley or broker affiliates of Morgan Stanley. In  order
for  Morgan Stanley or  its affiliates to effect  any portfolio transactions for
the Fund, the commissions, fees or other remuneration received by Morgan Stanley
or such affiliates must be reasonable and fair compared to the commissions, fees
or other  remuneration  paid to  other  brokers in  connection  with  comparable
transactions   involving  similar  securities  being  purchased  or  sold  on  a
securities exchange during a comparable  period of time. Furthermore, the  Board
of    Directors    of    the    Fund,   including    a    majority    of   those
 
                                       28
<PAGE>
Directors who are  not "interested persons,"  as defined in  the 1940 Act,  have
adopted   procedures  which  are   reasonably  designed  to   provide  that  any
commissions,  fees  or  other  remuneration  paid  to  Morgan  Stanley  or  such
affiliates are consistent with the foregoing standard.
 
    Portfolio  securities will not be  purchased from or through,  or sold to or
through, the Adviser or Morgan Stanley  or any "affiliated persons," as  defined
in  the 1940 Act of Morgan Stanley  when such entities are acting as principals,
except to the extent permitted by law.
 
    Although the  Portfolio will  not invest  for short-term  trading  purposes,
investment securities may be sold from time to time without regard to the length
of  time they have been held. It is anticipated that under normal circumstances,
the annual portfolio turnover rate will not exceed 100%. High portfolio turnover
involves correspondingly greater transaction costs which will be borne  directly
by  the respective Portfolio. In addition, high portfolio turnover may result in
more capital gains which would be taxable to the shareholders of the Portfolio.
 
                              GENERAL INFORMATION
 
DESCRIPTION OF COMMON STOCK
 
    The Fund  was organized  as a  Maryland corporation  on June  16, 1988.  The
Articles  of Incorporation, as amended and restated, permit the Fund to issue up
to 34 billion shares of common stock,  with $.001 par value per share.  Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number  of shares the  Fund is authorized  to issue without  the approval of the
shareholders of the  Fund. Subject  to the  notice period  to shareholders  with
respect to shares held by the shareholders, the Board of Directors has the power
to  designate one or more classes of shares  of common stock and to classify and
reclassify any  unissued shares  with respect  to such  classes. The  shares  of
common  stock of each  portfolio are currently classified  into two classes, the
Class A shares and the Class B  shares, except for the International Small  Cap,
Money  Market and  Municipal Money Market  Portfolios, which only  offer Class A
shares.
 
    The shares of the Portfolio, when issued, will be fully paid, nonassessable,
fully transferable and redeemable at the  option of the holder. The shares  have
no  preference  as  to  conversion,  exchange,  dividends,  retirement  or other
features and  have no  pre-emptive  rights. The  shares  of the  Portfolio  have
non-cumulative  voting rights, which means that the  holders of more than 50% of
the shares voting for the election of Directors can elect 100% of the  Directors
if  they choose  to do so.  Persons or organizations  owning 25% or  more of the
outstanding shares of the Portfolio may be presumed to "control" (as defined  in
the  1940 Act) the  Portfolio. Under Maryland  law, the Fund  is not required to
hold an annual meeting of  its shareholders unless required  to do so under  the
1940 Act.
 
REPORTS TO SHAREHOLDERS
 
    The  Fund will send to its  shareholders annual and semi-annual reports; the
financial statements  appearing in  annual reports  are audited  by  independent
accountants.  Monthly unaudited portfolio  data is also  available from the Fund
upon request.
 
    In addition, the Adviser, or its agent, as Transfer Agent, will send to each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
 
                                       29
<PAGE>
CUSTODIAN
 
    As of September  1, 1995, domestic  securities and cash  are held by  Chase,
which  replaced U.S.  Trust as  the Fund's domestic  custodian. Chase  is not an
affiliate of  the Adviser  or  the Distributor.  Morgan Stanley  Trust  Company,
Brooklyn,  New York ("MSTC"),  an affiliate of the  Adviser and the Distributor,
acts as the Fund's custodian for  foreign assets held outside the United  States
and  employs subcustodians  approved by  the Board of  Directors of  the Fund in
accordance with regulations of  the Securities and  Exchange Commission for  the
purpose  of providing  custodial services  for such  assets. MSTC  may also hold
certain domestic assets for  the Fund. For more  information on the  custodians,
see "General Information -- Custody Arrangements" in the Statement of Additional
Information.
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
    Chase   Global   Funds  Services   Company,   73  Tremont   Street,  Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
 
INDEPENDENT ACCOUNTANTS
 
    Price Waterhouse  LLP serves  as independent  accountants for  the Fund  and
audits the annual financial statements of each portfolio.
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       30
<PAGE>
<TABLE>
<CAPTION>

   MORGAN STANLEY INSTITUTIONAL FUND, INC.
          U.S. REAL ESTATE PORTFOLIO
          P.O. BOX 2798, BOSTON, MA 02208-2798

- ---------------------------------------------------------------------------------------------------------------

                           ACCOUNT REGISTRATION FORM
- ---------------------------------------------------------------------------------------------------------------
<S>                        <C>
ACCOUNT INFORMATION        If you need assistance in filling out this form     
Fill in where applicable   for the Morgan Stanley Institutional Fund, please   
                           contact your Morgan Stanley representative or call  
                           us toll free 1-(800)-548-7786. Please print all     
                           items except signature, and mail to the Fund at the
                           address above.

- ---------------------------------------------------------------------------------------------------------------
A)  REGISTRATION
    1. INDIVIDUAL            1. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
                                 First Name           Initial              Last Name
    2. JOINT TENANTS         2. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       (RIGHTS OF                First Name           Initial              Last Name
       SURVIVORSHIP            / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       PRESUMED UNLESS           First Name           Initial              Last Name
       TENANCY IN COMMON 
       IS INDICATED)      
- ---------------------------------------------------------------------------------------------------------------
    3. CORPORATIONS,        3.  / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       TRUSTS AND OTHERS       
       Please call the          / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       Fund for additional
       documents that may       / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       be required to set 
       up account and to 
       authorize transactions.
                                Type of / / INCORPORATED / / UNINCORPORATED / / PARTNERSHIP / / UNIFORM GIFT/TRANSFER TO MINOR 
                                Registration:                 ASSOCIATION                   (ONLY ONE CUSTODIAN AND MINOR PERMITTED)


                                / / TRUST __________________________________     / / OTHER (Specify) ______________________________
- ---------------------------------------------------------------------------------------------------------------
B)  MAILING ADDRESS         Street or P.O. Box / / / / / / / / / / / / / / / / / / / / / / / / / / / /

    Please fill in 
    completely, including   City / / / / / / / / / / / / / State / / / Zip / / / / / /-/ / / / / / / / 
    telephone number(s).
                            Home                                   Business
                            Telephone No./ / / /-/ / / /-/ / / / / Telephone No./ / / /-/ / / /-/ / / /
                            / / United States  / / Resident  / /Non-Resident Alien:
                                Citizen            Alien        Indicate Country of Residence _________
- ---------------------------------------------------------------------------------------------------------------
C)  TAXPAYER                PART 1. Enter your Taxpayer         C) IMPORTANT TAX INFORMATION 
    IDENTIFICATION          Identification Number. For most          You (as a payee) are required by
    NUMBER                  individual taxpayers, this is your     law to provide us (as payer) with
    If the account is in    Social Security Number.                your correct Taxpayer Identification
    more than one name,     TAXPAYER IDENTIFICATION NUMBER         Number. Accounts that have a missing
    CIRCLE THE NAME OF THE    / / / /-/ / / / / / / / /            or incorrect Taxpayer Identification
    PERSON WHOSE TAXPAYER               OR                         Number will be subject to backup
    IDENTIFICATION NUMBER       SOCIAL SECURITY NUMBER             withholding at a 31% rate on dividends,
    IS PROVIDED IN SECTION    / / / /-/ / /-/ / / / /              distributions and other payments.
    A) ABOVE. If no name      PART 2. BACKUP WITHHOLDING           If you have not provided us with
    is circled, the number    / / Check this box if you are        your correct taxpayer identification
    will be considered to be  NOT subject to Backup                number, you may be subject to 
    that of the last name     Withholding under the                a $50 penalty imposed by the Internal
    listed. For Custodian     provisions of Section                Revenue Service.
    account of a minor        3406(a)(1)(C) of the Internal          Backup withholding is not an
    (Uniform Gift/Transfer    Revenue Code.                        additional tax; the tax liability of
    to Minor Act), give the                                        persons subject to backup withholding
    Social Security Number                                         will be reduced by the amount of tax
    of the minor.                                                  withheld. If withholding results in
                                                                   an overpayment of taxes, a refund 
                                                                   may be obtained. You may be notified
                                                                   that you are subject to backup 
                                                                   withholding under Section 3406(a)(1)(C)
                                                                   of the Internal Revenue Code because you
                                                                   have underreported interest or dividends
                                                                   or you were required to but failed to
                                                                   file a return which would have included a
                                                                   reportable interest or dividend payment. IF
                                                                   YOU HAVE NOT BEEN SO NOTIFIED, CHECK THE
                                                                   BOX IN PART 2 AT LEFT.

- ---------------------------------------------------------------------------------------------------------------

D)  PORTFOLIO AND          For Purchase of the following Portfolio:     
    CLASS SELECTION        U.S. Real Estate Portfolio                 / / Class A Shares $____ / / Class B Shares $____
    (Class A shares
    minimum $500,000
    for each Portfolio                                                      Total Initial Investment $_____________
    and Class B shares
    minimum $100,000 for
    each Portfolio).
    Please indicate
    class and amount.
    

- ---------------------------------------------------------------------------------------------------------------
   
E)  METHOD OF   Payment by:
    INVESTMENT  / / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND, INC.--PORTFOLIO NAME)
    Please
    indicate
    manner of   / / Exchange $____________ From________________       / / / / / / / / / / /-/ /
    payment.                                Name of Portfolio              Account No.

               / / Account previously established by: 

               / / Phone exchange / / Wire on___________________       / / / / / / / / / / / /-/ /
                                                          Date             Account No.            (Check
                                                                 (Previously assigned by the Fund) Digit)
    
 
<PAGE>

- ---------------------------------------------------------------------------------------------------------------

F)  DISTRIBUTION                                       Income dividends and capital gains distributions (if any) will
    OPTION                                             be reinvested in additional shares unless either box below is
                                                       checked.

                                                       / / Income dividends to be paid in cash, capital
                                                           gains distributions (if any) in shares.

                                                      / /  Income dividends and capital gains distributions
                                                           (if any) to be paid in cash.

- ---------------------------------------------------------------------------------------------------------------


G)  TELEPHONE                    / / I/we hereby authorize the Fund and its      ______________________   ________________
    REDEMPTION                       agents to honor any telephone requests      Name of COMMERCIAL Bank  Bank Account No.
    Please select at time of         to wire redemption proceeds to the            (Not Savings Bank)
    initial application if you       commercial bank indicated at rightand/or 
    wish to redeem shares by         mail redemption proceeds to the name and                             ________________
    telephone. A SIGNATURE           address in which my/our fund account is                                 Bank ABA No.
    GUARANTEE IS REQUIRED IF         registered if such requests are believed 
    BANK ACCOUNT IS NOT              to be authentic.                           _________________________________________________
    REGISTERED IDENTICALLY TO    The Fund and the Fund's Transfer Agent will    Name(s) in which your BANK Account is Established
    YOUR FUND ACCOUNT.           employ reasonable procedures to confirm that
                                 instructions communicated by telephone are     _________________________________________________
    TELEPHONE REQUESTS FOR       genuine. These procedures include requiring                 Bank's Street Address
    REDEMPTIONS WILL NOT BE      the investor to provide certain personal
    HONORED UNLESS THE BOX IS    identification information at the time an      _________________________________________________
    CHECKED.                     account is opened and prior to effecting each  City                    State                Zip
                                 transaction requested by telephone. In addition,
                                 all telephone transaction requests will be recorded
                                 and investors may be required to provide additional
                                 telecopied written instructions of transaction
                                 requests. Neither the Fund nor the Transfer Agent will
                                 be responsible for any loss, liability, cost or expense
                                 for following instructions received by telephone that
                                 it reasonably believes to be genuine.


- ---------------------------------------------------------------------------------------------------------------

H)  INTERESTED PARTY
    OPTION
    In addition to the account   _________________________________________________________________
    statement sent to my/our                                 Name
    registered address, I/we     _________________________________________________________________
    hereby authorize the fund    
    to mail duplicate            _________________________________________________________________
    statements to the name and                              Address
    address provided at right.
                                 _________________________________________________________________
                                  City                      State                     Zip Code

- ---------------------------------------------------------------------------------------------------------------

I)  DEALER 
    INFORMATION                  _______________________  _______________________________  ___________
                                 Representative Name          Representative No.             Branch No.

- ---------------------------------------------------------------------------------------------------------------

J)  SIGNATURE OF        The undersigned certify(ies)  that I/we  have full  authority and  legal
    ALL HOLDERS         capacity  to purchase and redeem shares of the Fund and affirm that I/we
    AND TAXPAYER        have received a current Prospectus  of the Morgan Stanley  Institutional
    CERTIFICATION       Fund,  Inc. and agree to  be bound by its  terms. UNDER THE PENALTIES OF
    Sign Here >         PERJURY, I/WE CERTIFY THAT THE INFORMATION PROVIDED IN SECTION C)
                        ABOVE IS TRUE, CORRECT AND COMPLETE.

                        (X)                                 (X)
                        __________________________________  ______________________________________
                        Signature                Date       Signature                  Date


                        (X)                                 (X)
                        __________________________________  ______________________________________
                        Signature                Date       Signature                  Date

- ---------------------------------------------------------------------------------------------------------------


</TABLE>


<PAGE>
                 (This page has been left blank intentionally.)
<PAGE>
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
 
  NO  DEALER, SALES  REPRESENTATIVE OR ANY  OTHER PERSON HAS  BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE  CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS  HAVING BEEN AUTHORIZED BY THE FUND  OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF  THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION  TO
ANY  PERSON TO WHOM  IT IS UNLAWFUL TO  MAKE SUCH OFFER  OR SOLICITATION IN SUCH
JURISDICTION.
 
                           --------------------------
 
                               TABLE OF CONTENTS
 
   
<TABLE>
<S>                                                 <C>
                                                    PAGE
                                                    ----
Fund Expenses.....................................    2
Financial Highlights..............................    4
Prospectus Summary................................    6
Investment Objective and Policies.................   10
Additional Investment Information.................   12
Investment Limitations............................   15
Management of the Fund............................   16
Purchase of Shares................................   18
Redemption of Shares..............................   22
Shareholder Services..............................   24
Valuation of Shares...............................   25
Performance Information...........................   26
Dividends and Capital Gains Distributions.........   26
Taxes.............................................   26
Portfolio Transactions............................   28
General Information...............................   29
Account Registration Form
</TABLE>
    
 
                           U.S. REAL ESTATE PORTFOLIO
 
                                PORTFOLIO OF THE
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
 
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
 
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                      P.O. BOX 2798, BOSTON, MA 02208-2798
 
- ---------------------------------------
- ---------------------------------------
- ---------------------------------------
- ---------------------------------------
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
     ----------------------------------------------------------------------
 
                         INTERNATIONAL MAGNUM PORTFOLIO
 
                               A PORTFOLIO OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
 
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
 
                                ----------------
   
    Morgan  Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company, or mutual fund, which offers redeemable shares in
a   series   of   diversified   and   non-diversified   investment    portfolios
("portfolios").   The  Fund   currently  consists   of  twenty-eight  portfolios
representing a  broad range  of  investment choices.  The  Fund is  designed  to
provide clients with attractive alternatives for meeting their investment needs.
This prospectus (the "Prospectus") pertains to the Class A and Class B shares of
the  International Magnum Portfolio  (the "Portfolio"). The Class  A and Class B
shares currently  offered by  the Portfolio  have different  minimum  investment
requirements  and fund  expenses. Shares of  the portfolios are  offered with no
sales  charge  or  exchange  or  redemption  fee  (with  the  exception  of  the
International Small Cap Portfolio).
    
   
    The  INTERNATIONAL MAGNUM PORTFOLIO seeks  long-term capital appreciation by
investing primarily in equity securities of non-U.S. issuers in accordance  with
EAFE   country  (as  defined  in  "Investment  Objective  and  Policies"  below)
weightings determined by the Portfolio's investment adviser.
    
   
    INVESTORS SHOULD NOTE THAT THE PORTFOLIO MAY  INVEST UP TO 10% OF ITS  TOTAL
ASSETS IN RESTRICTED SECURITIES, AND UP TO 25% OF ITS TOTAL ASSETS IN RESTRICTED
SECURITIES THAT ARE RULE 144A SECURITIES. SEE "ADDITIONAL INVESTMENT INFORMATION
- --   NON-PUBLICLY   TRADED   SECURITIES,  PRIVATE   PLACEMENTS   AND  RESTRICTED
SECURITIES." INVESTMENTS  IN  RESTRICTED  SECURITIES  IN EXCESS  OF  5%  OF  THE
PORTFOLIO'S  TOTAL ASSETS MAY BE CONSIDERED  A SPECULATIVE ACTIVITY, MAY INVOLVE
GREATER RISK AND MAY INCREASE THE PORTFOLIO'S EXPENSES.
    
 
    The Fund is designed  to meet the investment  needs of discerning  investors
who  place a premium on quality and  personal service. With Morgan Stanley Asset
Management  Inc.  as   Adviser  and   Administrator  (the   "Adviser"  and   the
"Administrator"),  and with Morgan Stanley & Co. Incorporated ("Morgan Stanley")
as Distributor, the  Fund makes available  to institutional and  high net  worth
individual  investors a series  of portfolios which  benefit from the investment
expertise and commitment to  excellence associated with  Morgan Stanley and  its
affiliates.
   
    This Prospectus is designed to set forth concisely the information about the
Fund  that a prospective investor should know  before investing and it should be
retained for future reference. The  Fund offers additional portfolios which  are
described  in other prospectuses and under  "Prospectus Summary" below. The Fund
currently offers the following portfolios:  (i) GLOBAL AND INTERNATIONAL  EQUITY
- --  Active Country Allocation, Asian  Equity, Emerging-Markets, European Equity,
Global Equity, Gold, International  Equity, International Magnum,  International
Small  Cap, Japanese Equity  and Latin American Portfolios;  (ii) U.S. EQUITY --
Aggressive Equity, Emerging  Growth, Equity  Growth, MicroCap,  Small Cap  Value
Equity,  U.S. Real  Estate and Value  Equity Portfolios; (iii)  EQUITY AND FIXED
INCOME -- Balanced Portfolio; (iv) FIXED INCOME -- Emerging Markets Debt,  Fixed
Income,   Global  Fixed  Income,  High  Yield,  Mortgage-Backed  Securities  and
Municipal Bond Portfolios; and  (v) MONEY MARKET --  Money Market and  Municipal
Money Market Portfolios. Additional information about the Fund is contained in a
"Statement  of Additional Information," dated May 1, 1996, which is incorporated
herein  by  reference.   The  Statement  of   Additional  Information  and   the
prospectuses  pertaining to the other portfolios  of the Fund are available upon
request and without charge  by writing or  calling the Fund  at the address  and
telephone number set forth above.
    
   
  THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES AND
   EXCHANGE  COMMISSION  OR ANY  STATE SECURITIES  COMMISSION, NOR  HAS THE
     SECURITIES AND EXCHANGE COMMISSION OR ANY STATE SECURITIES  COMMISSION
     ASSED  UPON  THE  ACCURACY  OR  ADEQUACY  OF  THIS  PROSPECTUS.  ANY
                 REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.
    
   
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1996.
    
<PAGE>
                                 FUND EXPENSES
 
    The  following table illustrates all expenses and fees that a shareholder of
the International Magnum Portfolio will incur:
   
<TABLE>
<CAPTION>
SHAREHOLDER TRANSACTION EXPENSES
- ------------------------------------------------------------------------------------------
<S>                                                                                         <C>
Maximum Sales Load Imposed on Purchases
  Class A.................................................................................        None
  Class B.................................................................................        None
Maximum Sales Load Imposed on Reinvested Dividends
  Class A.................................................................................        None
  Class B.................................................................................        None
Deferred Sales Load
  Class A.................................................................................        None
  Class B.................................................................................        None
Redemption Fees
  Class A.................................................................................        None
  Class B.................................................................................        None
Exchange Fees
  Class A.................................................................................        None
  Class B.................................................................................        None
 
<CAPTION>
ANNUAL FUND OPERATING EXPENSES
- ------------------------------------------------------------------------------------------
<S>                                                                                         <C>
 (AS A PERCENTAGE OF AVERAGE NET ASSETS)
Management Fee (Net of Fee Waiver)*
  Class A.................................................................................       0.48%
  Class B.................................................................................       0.48%
12b-1 Fees
  Class A.................................................................................        None
  Class B.................................................................................       0.25%
Other Expenses
  Class A.................................................................................       0.52%
  Class B.................................................................................       0.52%
                                                                                            -----------
Total Operating Expenses (Net of Fee Waivers)*
  Class A.................................................................................       1.00%
  Class B.................................................................................       1.25%
                                                                                            -----------
                                                                                            -----------
</TABLE>
    
 
- ------------------------
   
* The Adviser has  agreed to  waive its advisory  fees and/or  to reimburse  the
  Portfolio, if necessary, if such fees would cause the Portfolio's total annual
  operating expenses, as a percentage of average daily net assets, to exceed the
  percentages  set  forth  in  the  table  above.  Absent  the  fee  waiver, the
  investment advisory  would be  0.80%.  Absent the  fee waiver  and/or  expense
  reimbursement,  the Portfolio's  total operating  expenses are  expected to be
  1.32% of the average daily net assets of  the Class A shares and 1.57% of  the
  average daily net assets of the Class B shares. As a result of this reduction,
  the Management Fee stated above is lower than the contractual fee stated under
  "Management  of the Fund." The Adviser reserves  the right to terminate any of
  its fee  waivers  and/or  expense  reimbursements at  any  time  in  its  sole
  discretion.  For further information on Fund  expenses, see "Management of the
  Fund."
    
 
                                       2
<PAGE>
   
    The purpose of the  table above is to  assist the investor in  understanding
the  various expenses that  an investor in  the Portfolio will  bear directly or
indirectly. The Class  A and Class  B expenses  and fees for  the Portfolio  are
based  on estimates, assuming that  the average daily net  assets of the Class A
shares and Class  B shares will  each be $50,000,000.  "Other Expenses"  include
Board  of Directors'  fees and  expenses, amortization  of organizational costs,
filing fees, professional  fees and costs  for shareholder reports.  Due to  the
continuous  nature of Rule  12b-1 fees, long  term Class B  shareholders may pay
more than  the  equivalent of  the  maximum front-end  sales  charges  otherwise
permitted  by  the  Rules  of  Fair  Practice  of  the  National  Association of
Securities Dealers, Inc. ("NASD").
    
 
    The following  example illustrates  the expenses  that you  would pay  on  a
$1,000  investment assuming (1) a 5% annual rate of return and (2) redemption at
the end of each time  period. As noted in the  table above, the Fund charges  no
redemption  fees  of any  kind.  The following  example  is based  on  the total
operating expenses of the Portfolio after fee waivers.
 
   
<TABLE>
<CAPTION>
                                                                       1 YEAR       3 YEARS     5 YEARS    10 YEARS
                                                                     -----------  -----------  ---------  -----------
<S>                                                                  <C>          <C>          <C>        <C>
International Magnum Portfolio
  Class A..........................................................   $      10    $      32   $   *       $   *
  Class B..........................................................   $      13    $      40   $   *       $   *
</TABLE>
    
 
- ------------------------
   
* Because the  Portfolio has  recently commenced  operations, the  Fund has  not
  projected expenses for the Portfolio beyond the 3-year period shown.
    
 
    THIS  EXAMPLE SHOULD  NOT BE CONSIDERED  A REPRESENTATION OF  PAST OR FUTURE
EXPENSES OR  PERFORMANCE. ACTUAL  EXPENSES MAY  BE GREATER  OR LESS  THAN  THOSE
SHOWN.
 
    The  Fund intends  to comply  with all  state laws  that restrict investment
company expenses. Currently, the  most restrictive state  law requires that  the
aggregate  annual expenses  of an  investment company  shall not  exceed two and
one-half percent (2 1/2%) of  the first $30 million  of average net assets,  two
percent (2%) of the next $70 million of average net assets, and one and one-half
percent (1 1/2%) of the remaining net assets of such investment company.
 
    The  Adviser has agreed to a reduction in  the amounts payable to it, and to
reimburse the Portfolio,  if necessary, if  in any  fiscal year the  sum of  the
Portfolio's expenses exceeds the limit set by applicable state law.
 
                                       3
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
   
    The   Fund  consists  of  twenty-eight  portfolios,  offering  institutional
investors and high net  worth individual investors a  broad range of  investment
choices coupled with the advantages of a no-load mutual fund with Morgan Stanley
and  its affiliates providing customized  services as Adviser, Administrator and
Distributor. Each portfolio offers Class A shares and, except the  International
Small Cap, Money Market and Municipal Money Market Portfolios, also offers Class
B  shares. Each portfolio has its own investment objective and policies designed
to meet its specific goals. This Prospectus pertains to the Class A and Class  B
shares of the International Magnum Portfolio.
    
 
   
    -The  INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation by
     investing primarily in equity securities of non-U.S. issuers in  accordance
     with EAFE country (as defined in "Investment Objective and Policies" below)
     weightings determined by the Adviser.
    
 
    The  other portfolios of the Fund  are described in other prospectuses which
may be obtained from the Fund at the address and phone number noted on the cover
of this Prospectus. The objectives of these other portfolios are listed below.
 
    GLOBAL AND INTERNATIONAL EQUITY:
 
    -The  ACTIVE   COUNTRY   ALLOCATION  PORTFOLIO   seeks   long-term   capital
     appreciation  by investing in accordance with country weightings determined
     by the  Adviser in  equity securities  of non-U.S.  issuers which,  in  the
     aggregate, replicate broad country indices.
 
    -The   ASIAN  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing primarily in equity securities of Asian issuers.
 
    -The CHINA GROWTH PORTFOLIO seeks to provide long-term capital  appreciation
     by  investing primarily  in equity  securities of  issuers in  The People's
     Republic of China, Hong Kong and Taiwan.
 
    -The EMERGING  MARKETS PORTFOLIO  seeks  long-term capital  appreciation  by
     investing primarily in equity securities of emerging country issuers.
 
    -The  EUROPEAN  EQUITY  PORTFOLIO seeks  long-term  capital  appreciation by
     investing primarily in equity securities of European issuers.
 
    -The  GLOBAL  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing  primarily in equity securities  of issuers throughout the world,
     including U.S. issuers.
 
    -The GOLD  PORTFOLIO  seeks  long-term  capital  appreciation  by  investing
     primarily  in equity securities of foreign  and domestic issuers engaged in
     gold-related activities.
 
    -The INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation  by
     investing primarily in equity securities of non-U.S. issuers.
 
   
    -The  INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital appreciation
     by investing primarily in equity securities of non-U.S. issuers with equity
     market capitalizations of less than $1 billion.
    
 
    -The JAPANESE  EQUITY  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing primarily in equity securities of Japanese issuers.
 
                                       4
<PAGE>
    -The  LATIN  AMERICAN  PORTFOLIO  seeks  long-term  capital  appreciation by
     investing primarily in equity securities of Latin American issuers and debt
     securities  issued  or   guaranteed  by  Latin   American  governments   or
     governmental entities.
 
    U.S. EQUITY:
 
    -The  AGGRESSIVE EQUITY  PORTFOLIO seeks  capital appreciation  by investing
     primarily in corporate equity and equity-linked securities.
 
    -The EMERGING  GROWTH  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing  primarily  in  growth-oriented equity  securities  of  small- to
     medium-sized corporations.
 
    -The  EQUITY  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing   in  growth-oriented  equity  securities  of  medium  and  large
     capitalization companies.
 
    -The MICROCAP PORTFOLIO  seeks long-term capital  appreciation by  investing
     primarily in growth-oriented equity securities of small corporations.
 
    -The  SMALL CAP VALUE EQUITY PORTFOLIO  seeks high long-term total return by
     investing in  undervalued  equity  securities  of  small-  to  medium-sized
     companies.
 
    -The  U.S.  REAL ESTATE  PORTFOLIO seeks  to  provide above  average current
     income and long-term capital appreciation by investing primarily in  equity
     securities  of companies in  the U.S. real  estate industry, including real
     estate investment trusts.
 
    -The VALUE EQUITY PORTFOLIO seeks high  total return by investing in  equity
     securities  which the  Adviser believes to  be undervalued  relative to the
     stock market in general at the time of purchase.
 
    EQUITY AND FIXED INCOME:
 
   
    -The BALANCED PORTFOLIO seeks high total return while preserving capital  by
     investing  in  a combination  of  undervalued equity  securities  and fixed
     income securities.
    
 
    FIXED INCOME:
 
    -The EMERGING MARKETS DEBT  PORTFOLIO seeks high  total return by  investing
     primarily   in  debt  securities   of  government,  government-related  and
     corporate issuers located in emerging countries.
 
    -The FIXED INCOME PORTFOLIO seeks to produce a high total return  consistent
     with the preservation of capital by investing in a diversified portfolio of
     fixed income securities.
 
    -The  GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real rate
     of return while preserving capital by investing in fixed income  securities
     of issuers throughout the world, including U.S. issuers.
 
    -The  HIGH YIELD PORTFOLIO seeks to maximize  total return by investing in a
     diversified portfolio of high  yield fixed income  securities that offer  a
     yield  above  that  generally available  on  debt securities  in  the three
     highest rating categories of the recognized rating services.
 
    -The MORTGAGE-BACKED SECURITIES PORTFOLIO seeks  to produce as high a  level
     of  current income  as is  consistent with  the preservation  of capital by
     investing  primarily  in  a  variety  of  investment-grade  mortgage-backed
     securities.
 
    -The  MUNICIPAL  BOND PORTFOLIO  seeks to  produce a  high level  of current
     income consistent  with the  preservation of  principal through  investment
     primarily  in municipal obligations,  the interest on  which is exempt from
     federal income tax.
 
                                       5
<PAGE>
    MONEY MARKET:
 
    -The MONEY MARKET PORTFOLIO  seeks to maximize  current income and  preserve
     capital  while maintaining  high levels  of liquidity  through investing in
     high quality money market instruments with remaining maturities of one year
     or less.
 
    -The MUNICIPAL MONEY MARKET PORTFOLIO  seeks to maximize current  tax-exempt
     income  and  preserve capital  while maintaining  high levels  of liquidity
     through investing in high-quality  money market instruments with  remaining
     maturities of one year or less which are exempt from federal income tax.
 
INVESTMENT MANAGEMENT
   
    Morgan  Stanley Asset Management  Inc., a wholly-owned  subsidiary of Morgan
Stanley Group  Inc.,  which,  together  with  its  affiliated  asset  management
companies,  at December 31, 1995 had approximately $57.4 billion in assets under
management as  an  investment  manager  or  as  a  fiduciary  adviser,  acts  as
investment  adviser to the Fund  and each of its  portfolios. See "Management of
the Fund -- Investment Adviser" and "Management of the Fund -- Administrator."
    
   
HOW TO INVEST
    
 
   
    Class A shares  of the Portfolio  are offered directly  to investors at  net
asset  value with no  sales commission or  12b-1 charges. Class  B shares of the
Portfolio are offered at net  asset value with no  sales commission, but with  a
12b-1  fee, which  is accrued daily  and paid  quarterly, equal to  0.25%, on an
annualized basis,  of  the Class  B  shares'  average daily  net  assets.  Share
purchases may be made by sending investments directly to the Fund or through the
Distributor. The minimum initial investment for shares in a Portfolio account is
$500,000  for Class A shares and $100,000 for Class B shares. Certain exceptions
to the foregoing minimums  apply to (1) Portfolio  accounts held by officers  of
the  Adviser and  its affiliates  and (2)  certain advisory  or asset allocation
accounts, such as Total Funds Management accounts, managed by Morgan Stanley  or
its affiliates, including the Adviser ("Managed Accounts"). The Adviser reserves
the  right in its sole  discretion to determine which  of such advisory or asset
allocation accounts shall be Managed Accounts. For information regarding Managed
Accounts, please contact your Morgan Stanley account representative or the  Fund
at  the telephone number provided  on the cover of  this Prospectus. The minimum
investment levels may be waived at the discretion of the Adviser for (i) certain
employees and customers of  Morgan Stanley or its  affiliates and certain  trust
departments,  brokers, dealers,  agents, financial  planners, financial services
firms, or investment advisers  that have entered into  an agreement with  Morgan
Stanley  or its affiliates; and (ii)  retirement and deferred compensation plans
and trusts used to fund such plans, including, but not limited to, those defined
in Section  401(a), 403(b)  or 457  of the  Internal Revenue  Code of  1986,  as
amended,  and "rabbi trusts". See "Purchase  of Shares -- Minimum Investment and
Account Sizes; Conversion from Class A to Class B Shares."
    
 
   
    The minimum subsequent investment for a Portfolio account is $1,000  (except
for  automatic  reinvestment of  dividends and  capital gains  distributions for
which there  is no  minimum). Such  subsequent investments  will be  applied  to
purchase  additional  shares  in the  same  class  held by  a  shareholder  in a
Portfolio account. See "Purchase of Shares -- Additional Investments."
    
 
                                       6
<PAGE>
   
HOW TO REDEEM
    
 
   
    Class A shares or  Class B shares  of the Portfolio may  be redeemed at  any
time, without cost, at the net asset value per share of shares of the applicable
class  next determined after  receipt of the  redemption request. The redemption
price may be more or less than the purchase price. Certain redemptions may cause
involuntary redemption or automatic conversion. Class  A or Class B shares  held
in  a Portfolio  account are  subject to  involuntary redemption  if shareholder
redemption(s) of such  shares reduces  the value of  such account  to less  than
$100,000  for a continuous 60-day period.  Involuntary redemption does not apply
to Managed Accounts, regardless of the value of such accounts. Class A shares in
a Portfolio account will convert to Class B shares if shareholder  redemption(s)
of  such shares reduces  the value of such  account to less  than $500,000 for a
continuous 60-day period. Class B shares in a Portfolio account will convert  to
Class  A shares if shareholder purchases of  additional Class B shares or market
activity cause the  value of  the Class  B shares  in the  Portfolio account  to
increase  to $500,000 or more. See "Purchase  of Shares -- Minimum Account Sizes
and Involuntary Redemption of Shares" and "Redemption of Shares."
    
 
   
RISK FACTORS
    
 
   
    The  investment  policies  of  the   Portfolio  entail  certain  risks   and
considerations  of which an investor should  be aware. The Portfolio will invest
in securities of foreign issuers, including issuers in emerging countries, which
are subject to certain risks not typically associated with domestic  securities,
including  (1) restrictions on foreign investment and on repatriation of capital
invested in  foreign  countries, (2)  currency  fluctuations, (3)  the  cost  of
converting  foreign currency into  U.S. dollars, (4)  potential price volatility
and lesser liquidity of shares traded  on foreign country securities markets  or
lack  of a secondary  trading market for  such securities and  (5) political and
economic risks, including the risk of nationalization or expropriation of assets
and the risk  of war.  In addition,  accounting, auditing,  financial and  other
reporting  standards in foreign  countries are not  equivalent to U.S. standards
and therefore, disclosure of  certain material information may  not be made  and
less  information may be  available to investors  investing in foreign countries
than in the United States. There is also generally less governmental  regulation
of  the  securities  industry  in  foreign  countries  than  the  United States.
Moreover, it may be more difficult to  obtain a judgment in a court outside  the
United   States.  See  "Investment  Objective   and  Policies"  and  "Additional
Investment Information." In  addition, the  Portfolio may  invest in  repurchase
agreements,  lend its portfolio securities, purchase securities on a when-issued
basis and  invest  in  forward  foreign currency  exchange  contracts  to  hedge
currency   risk  associated  with  investment  in  non-U.S.  dollar  denominated
securities. Each of  these investment strategies  involves specific risks  which
are   described  under  "Investment  Objective  and  Policies"  and  "Additional
Investment Information" herein and under "Investment Objectives and Policies" in
the Statement of Additional Information.
    
 
                                       7
<PAGE>
                       INVESTMENT OBJECTIVE AND POLICIES
 
    The investment objective of the International Magnum Portfolio is  described
below,  together with the  policies the Fund  employs in its  efforts to achieve
this objective. The  Portfolio's investment  objective is  a fundamental  policy
which  may not be changed without the  approval of a majority of the Portfolio's
outstanding voting securities.  There is  no assurance that  the Portfolio  will
attain   its  objective.  The  investment   policies  described  below  are  not
fundamental policies and may be changed without shareholder approval.
 
   
    The investment objective of  the Portfolio is  to provide long-term  capital
appreciation.  The  production  of  any current  income  is  incidental  to this
objective. The Portfolio seeks to  achieve its objective by investing  primarily
in  equity securities  of non-U.S. issuers  in accordance with  the EAFE country
(defined below)  weightings  determined by  the  Adviser. With  respect  to  the
Portfolio,  equity securities  include common and  preferred stocks, convertible
securities, and  rights  and warrants  to  purchase common  stocks.  The  equity
securities in which the Portfolio may invest may be denominated in any currency.
    
 
   
    The  countries in which  the Portfolio will invest  are those comprising the
Morgan Stanley Capital  International EAFE Index  (the "Index"), which  includes
Australia,  Japan,  New  Zealand, most  nations  located in  Western  Europe and
certain developed countries in  Asia, such as Hong  Kong and Singapore (each  an
"EAFE  country," and  collectively the  "EAFE countries").  At least  65% of the
total assets of the Portfolio will  be invested in equity securities of  issuers
in at least three different EAFE countries under normal circumstances.
    
 
   
    By  analyzing a variety of macroeconomic  and political factors, the Adviser
develops fundamental  projections  on comparative  interest  rates,  currencies,
corporate  profits and economic growth among  the various regions represented in
the Index.  These projections  will  be used  to establish  regional  allocation
strategies.  Within these regional allocations,  the Adviser then selects equity
securities among issuers of a region.
    
 
   
    The Adviser's approach in selecting among equity securities within a  region
comprised  of EAFE  countries is oriented  to individual stock  selection and is
value driven. The Adviser identifies  those equity securities which it  believes
to  be undervalued in relation  to the issuer's assets,  cash flow, earnings and
revenues. In  selecting investments,  the  Adviser utilizes  the research  of  a
number  of sources, including Morgan Stanley Capital International, an affiliate
of the Adviser located in Geneva, Switzerland. Portfolio holdings are  regularly
reviewed  and  subjected  to  fundamental  analysis  to  determine  whether they
continue to  conform to  the Adviser's  investment criteria.  Equity  securities
which no longer conform to such investment criteria will be sold.
    
 
   
    Although  the  Portfolio intends  to invest  primarily in  equity securities
listed on a  stock exchange  in an  EAFE country,  the Portfolio  may invest  in
equity  securities that are traded over the  counter or that are not admitted to
listing on a stock exchange or dealt in  a regulated market. As a result of  the
absence  of a public  trading market, such securities  may pose liquidity risks.
The Portfolio may also invest in private placements or initial public  offerings
in  the form of oversubscriptions.  Such investments generally entail short-term
liquidity risks. See "Additional  Investment Information -- Non-Publicly  Traded
Securities, Private Placements and Restricted Securities."
    
 
    The  Portfolio may invest  up to 10%  of its total  assets in (i) investment
funds with investment objectives similar to  that of the Portfolio and (ii)  for
temporary    purposes,    money    market    funds    and    pooled   investment
 
                                       8
<PAGE>
vehicles. If the Portfolio invests in other investment funds, stockholders  will
bear  not  only  their proportionate  share  of  the expenses  of  the Portfolio
(including operating expenses and fees of the Investment Adviser), but also will
indirectly bear similar expenses of the underlying investment fund.
 
   
    Although the Portfolio anticipates being fully invested in equity securities
of EAFE countries, the Portfolio may invest, under normal circumstances for cash
management purposes, up to 35% of  its total assets in certain short-term  (less
than  twelve months to maturity) and medium-term (not greater than five years to
maturity) debt securities  or hold  cash. In addition,  for temporary  defensive
purposes  during  periods in  which the  Adviser  believes changes  in economic,
financial or political conditions make it advisable, the Portfolio may invest up
to 100% of its total assets  in such short-term and medium-term debt  securities
or  hold cash.  The Portfolio will  not invest  in debt securities  that are not
rated at  least  investment grade  by  either Moody's  Investors  Service,  Inc.
("Moody's") or Standard & Poor's Corporation ("S&P"). See "Additional Investment
Information -- Debt Securities and Temporary Investments."
    
 
    Although  the  Portfolio will  not invest  for short-term  trading purposes,
investment securities may be sold from time to time without regard to the length
of time they have been held. It is anticipated that the annual turnover rate  of
the Portfolio will not exceed 100% under normal circumstances.
 
   
    Any  remaining assets of the Portfolio may be invested in certain securities
and obligations, including  derivative securities, as  set forth in  "Additional
Investment Information" below.
    
 
   
                       ADDITIONAL INVESTMENT INFORMATION
    
 
   
    DEBT  SECURITIES AND TEMPORARY INVESTMENTS.   The short-term and medium-term
debt securities in which the Portfolio may invest consist of (a) obligations  of
governments,   agencies  or  instrumentalities  of   any  member  state  of  the
Organization for Economic  Cooperation and Development  ("OECD"), including  the
United States; (b) bank deposits and bank obligations (including certificates of
deposit,  time deposits and  bankers' acceptances) of  banks organized under the
laws of any member state of  the OECD, including the United States,  denominated
in  any currency; (c)  finance company and corporate  commercial paper and other
short-term corporate debt obligations of  corporations organized under the  laws
of  any  member state  of the  OECD,  including the  United States,  meeting the
Portfolio's credit quality  standards, provided  that no  more than  20% of  the
Portfolio's  assets is invested in  any one of such  issuers. The short-term and
medium-term debt securities  in which  the Portfolio  may invest  will be  rated
investment  grade by recognized rating  services such as Moody's  or S&P (in the
case of Moody's and S&P,  meaning rated A or higher  by either), or if  unrated,
will be determined to be of comparable quality by the Adviser. During periods in
which   the  Adviser  believes  changes  in  economic,  financial  or  political
conditions make it advisable, for temporary defensive purposes the Portfolio may
reduce its holdings  in equity and  other securities and  may invest in  certain
short-term  (less than twelve  months to maturity)  and medium-term (not greater
than five years to maturity) debt securities or may hold cash.
    
 
   
    DERIVATIVES.  The  Portfolio may  invest in certain  derivatives, which  are
financial  products or instruments that derive their  value from the value of an
underlying asset,  reference rate  or index.  The following  are derivatives  in
which  the  Portfolio  may  invest:  convertible  securities,  warrants, forward
foreign currency exchange contracts,  foreign currency futures contracts,  stock
options, stock index futures contracts and when-
    
 
                                       9
<PAGE>
   
issued  and  delayed  delivery  securities. See  elsewhere  in  this "Additional
Investment Information" section for  descriptions of these various  instruments,
and  see "Investment Objectives and Policies" for more information regarding any
investment policies or limitations applicable to their use.
    
 
   
    FOREIGN CURRENCY HEDGING TRANSACTIONS.   In order  to hedge against  foreign
currency  exchange  rate risks,  the Portfolio  may  enter into  forward foreign
currency exchange  contracts  ("forward contracts"),  foreign  currency  futures
contracts  and options on  such contracts, and  purchase put or  call options on
foreign currencies. A  forward contract  involves an obligation  to purchase  or
sell  an amount of a specified currency at a future date, which may be any fixed
number of days from the  date of the contract agreed  upon by the parties, at  a
price  set at  the time  of the  contract. Forward  contracts are  traded in the
interbank market  conducted directly  between  currency traders  (usually  large
commercial  banks). Except when used for hedging, the Portfolio's custodian will
place cash, U.S.  government securities,  or high-grade debt  securities into  a
segregated  account of  the Portfolio  in an  amount equal  to the  value of the
Portfolio's total assets committed to the consummation of forward contracts.  If
the  value  of  the  securities  placed  in  the  segregated  account  declines,
additional cash or securities will be placed in the account on a daily basis  so
that  the value  of the  account will  be at  least equal  to the  amount of the
Portfolio's  commitments  with  respect  to  such  contracts.  See   "Investment
Objective  and Policies --  Forward Foreign Currency  Exchange Contracts" in the
Statement of Additional Information.
    
 
   
    A foreign  currency futures  contract  is a  standardized contract  for  the
future  delivery of a specified amount of a foreign currency at a future date at
a price set  at the  time of the  contract. Foreign  currency futures  contracts
traded  in the  U.S. are  traded on  regulated exchanges.  Parties to  a futures
contract must  make  initial "margin"  deposits  to secure  performance  of  the
contract,  which generally range from 2% to 5% of the contract price. There also
are requirements to make "variation" margin deposits as the value of the futures
contract fluctuates. The Portfolio may  not enter into foreign currency  futures
contracts  if the aggregate amount of initial margin deposits on the Portfolio's
futures positions, including stock index futures contracts (which are  discussed
below),  would  exceed 5%  of the  value  of the  Portfolio's total  assets. The
Portfolio also  will  be required  to  segregate  assets to  cover  its  futures
contracts obligations.
    
 
   
    At  the maturity of a forward or  futures contract, the Portfolio may either
accept or make delivery of the currency  specified in the contract or, prior  to
maturity,  enter into a  closing purchase transaction  involving the purchase or
sale of an offsetting  contract. Closing purchase  transactions with respect  to
forward  contracts are usually effected with the  currency trader who is a party
to the original forward contract. Closing purchase transactions with respect  to
futures  contracts are  effected on an  exchange. The Portfolio  will only enter
into such a forward or futures contract if  it is expected that there will be  a
liquid  market in which  to close out  such contract. There  can, however, be no
assurance that such a liquid  market will exist in which  to close a forward  or
futures contract, in which case the Portfolio may suffer a loss.
    
 
   
    Purposes  for which such contracts may  be used include protecting against a
decline in a foreign currency against the U.S. dollar between the trade date and
settlement date when the Portfolio purchases or sells securities, locking in the
U.S. dollar value of dividends declared on securities held by the Portfolio  and
generally  protecting the U.S. dollar value  of securities held by the Portfolio
against exchange  rate fluctuations.  Such  contracts will  be  used only  as  a
protective measure against the effects of fluctuating rates of currency exchange
and  exchange control regulations. While such  contracts may limit losses to the
Portfolio as a  result of exchange  rate fluctuation, they  will also limit  any
gains that may otherwise have been realized.
    
 
                                       10
<PAGE>
   
    The  Portfolio  may  attempt  to  accomplish  objectives  similar  to  those
described above with respect  to forward and futures  contracts for currency  by
means  of purchasing put or  call options on foreign  currencies on exchanges. A
put option gives  the Portfolio the  right to  sell a currency  at the  exercise
price  until the expiration of the option. A call option gives the Portfolio the
right to purchase a currency at the  exercise price until the expiration of  the
option.
    
 
   
    FOREIGN  INVESTMENT.   The Portfolio  may invest  in U.S. dollar-denominated
securities  of  foreign  issuers  trading  in  U.S.  markets  and  in   non-U.S.
dollar-denominated  securities of  foreign issuers. Investment  in securities of
foreign issuers  and in  foreign branches  of domestic  banks involves  somewhat
different  investment  risks than  those affecting  securities of  U.S. domestic
issuers. There may  be limited  publicly available information  with respect  to
foreign  issuers,  and  foreign issuers  are  not generally  subject  to uniform
accounting,  auditing   and  financial   and  other   reporting  standards   and
requirements comparable to those applicable to U.S. companies. There may also be
less  government  supervision and  regulation  of foreign  securities exchanges,
brokers and listed companies  than in the U.S.  Many foreign securities  markets
have  substantially  less volume  than U.S.  national securities  exchanges, and
securities of  some foreign  issuers  are less  liquid  and more  volatile  than
securities  of  comparable  domestic issuers.  Brokerage  commissions  and other
transaction costs on foreign securities  exchanges are generally higher than  in
the  U.S.  Dividends and  interest paid  by  foreign issuers  may be  subject to
withholding and  other foreign  taxes,  which may  decrease  the net  return  on
foreign  investments as compared to dividends and interest paid to the Portfolio
by U.S. companies.  It is not  expected that the  Portfolio or its  shareholders
would  be able to claim a credit for  U.S. tax purposes with respect to any such
foreign taxes.  See  "Taxes."  Additional risks  include  future  political  and
economic  developments, the possibility that a foreign jurisdiction might impose
or  change  withholding  taxes  on  income  payable  with  respect  to   foreign
securities,  possible seizure,  nationalization or expropriation  of the foreign
issuer or foreign  deposits and  the possible adoption  of foreign  governmental
restrictions  such  as exchange  controls. Many  of  the emerging  or developing
countries may  have  less  stable political  environments  than  more  developed
countries.  Also,  it may  be more  difficult to  obtain a  judgment in  a court
outside the  United States.  Investments in  securities of  foreign issuers  are
frequently  denominated in foreign currencies, and the Portfolio may temporarily
hold uninvested reserves in bank deposits in foreign currencies. Therefore,  the
value  of the  Portfolio's assets  as measured in  U.S. dollars  may be affected
favorably or unfavorably by  changes in currency rates  and in exchange  control
regulations,  and the Portfolio  may incur costs  in connection with conversions
between various currencies.
    
 
    INVESTMENT COMPANIES.  Some foreign countries have laws and regulations that
currently  preclude  direct  foreign  investment  in  the  securities  of  their
companies.  However, indirect foreign investment  in the securities of companies
listed and traded  on the  stock exchanges in  these countries  is permitted  by
certain   foreign  countries  through  investment   companies  which  have  been
specifically authorized. The Portfolio may invest in these investment  companies
subject to the provisions of the Investment Company Act of 1940, as amended (the
"1940  Act"), and  other applicable  laws as  discussed below  under "Investment
Restrictions." If  the  Portfolio  invests in  such  investment  companies,  the
Portfolio's  shareholders will  bear not only  their proportionate  share of the
expenses of the  Portfolio (including  operating expenses  and the  fees of  the
Adviser),  but  also will  indirectly bear  similar  expenses of  the underlying
investment companies. Certain  of the  investment companies referred  to in  the
preceding paragraph are advised by the Adviser. The Portfolio may, to the extent
permitted  under  the  1940  Act  and  other  applicable  law,  invest  in these
investment companies. If the Portfolio does elect to make an investment in  such
an  investment company, it will only  purchase the securities of such investment
company in the secondary market.
 
                                       11
<PAGE>
    LOANS OF PORTFOLIO  SECURITIES.  The  Portfolio may lend  its securities  to
brokers, dealers, domestic and foreign banks or other financial institutions for
the purpose of increasing its net investment income. These loans must be secured
continuously  by cash or equivalent collateral or by a letter of credit at least
equal to the  market value  of the securities  loaned plus  accrued interest  or
income.  There may be risks of delay in  recovery of the securities or even loss
of rights  in  the  collateral  should  the  borrower  of  the  securities  fail
financially.  The  Portfolio will  not enter  into securities  loan transactions
exceeding, in the  aggregate, 33  1/3% of the  market value  of the  Portfolio's
total  assets.  For  more  detailed information  about  securities  lending, see
"Investment Objective and Policies" in the Statement of Additional Information.
 
    MONEY MARKET INSTRUMENTS.   The Portfolio  is permitted to  invest in  money
market   instruments,  although  the  Portfolio  intends  to  stay  invested  in
securities satisfying its primary investment objective to the extent  practical.
The  Portfolio may  make money  market investments  pending other  investment or
settlement for  liquidity, or  in adverse  market conditions.  The money  market
investments  permitted  for  the  Portfolio  include  obligations  of  the  U.S.
Government and  its  agencies  and  instrumentalities,  obligations  of  foreign
sovereignties,   other   debt  securities,   commercial  paper   including  bank
obligations, certificates  of  deposit  (including  Eurodollar  certificates  of
deposit)  and repurchase agreements.  For more detailed  information about these
money market investments,  see "Description  of Securities and  Ratings" in  the
Statement of Additional Information.
 
    NON-PUBLICLY   TRADED   SECURITIES,   PRIVATE   PLACEMENTS   AND  RESTRICTED
SECURITIES.  The Portfolio may invest in securities that are neither listed on a
stock  exchange  nor   traded  over-the-counter,   including  privately   placed
securities.  Such  unlisted equity  securities may  involve  a higher  degree of
business and financial risk that can  result in substantial losses. As a  result
of the absence of a public trading market for these securities, they may be less
liquid  than publicly traded securities. Although these securities may be resold
in privately negotiated transactions, the prices realized from these sales could
be less than those  originally paid by  the Portfolio or less  than what may  be
considered  the fair  value of  such securities.  Further, more  companies whose
securities are not  publicly traded  may not be  subject to  the disclosure  and
other  investor  protection  requirements  which might  be  applicable  if their
securities  were  publicly  traded.  If  such  securities  are  required  to  be
registered  under the securities laws of  one or more jurisdictions before being
resold, the Portfolio may be required to bear the expenses of registration. As a
general matter, the Portfolio may not invest more than 15% of its net assets  in
illiquid  securities,  including  securities  for  which  there  is  no  readily
available secondary market, nor more than 10% of its total assets in  securities
that  are restricted from  sale to the  public without registration ("Restricted
Securities") under the  Securities Act  of 1933,  as amended  (the "1933  Act").
Nevertheless,  subject  to  the  foregoing  limit  on  illiquid  securities, the
Portfolio may invest up to 25% of its total assets in Restricted Securities that
can be offered and sold to qualified institutional buyers under Rule 144A  under
that  Act ("144A Securities"). The Board of Directors has adopted guidelines and
delegated to the Adviser, subject to the supervision of the Board of  Directors,
the  daily  function  of  determining  and  monitoring  the  liquidity  of  144A
securities. Rule 144A securities may become illiquid if qualified  institutional
buyers  are not  interested in acquiring  the securities.  Investors should note
that investments of 5% of the Portfolio's total assets in restricted  securities
may  be  considered a  speculative  activity and  may  involve greater  risk and
expense to the Portfolio.
 
    REPURCHASE AGREEMENTS.  The Portfolio  may enter into repurchase  agreements
with  brokers, dealers or  banks that meet the  credit guidelines established by
the Fund's Board of Directors. In  a repurchase agreement, the Portfolio buys  a
security  from a seller  that has agreed  to repurchase it  at a mutually agreed
upon date and price, reflecting the interest rate effective for the term of  the
agreement. The term of these agreements is usually
 
                                       12
<PAGE>
from overnight to one week and never exceeds one year. Repurchase agreements may
be  viewed  as a  fully collateralized  loan of  money by  the Portfolio  to the
seller. The Portfolio always  receives securities with a  market value at  least
equal to the purchase price (including accrued interest) as collateral, and this
value is maintained during the term of the agreement. If the seller defaults and
the  collateral value declines, the Portfolio  might incur a loss. If bankruptcy
proceedings  are  commenced  with  respect   to  the  seller,  the   Portfolio's
realization  upon the  collateral may  be delayed  or limited.  The aggregate of
certain repurchase agreements and  certain other investments  is limited as  set
forth under "Investment Limitations."
   
    STOCK  OPTIONS AND INDEX FUTURES CONTRACTS.  The Portfolio may utilize stock
options and stock index  futures contracts with respect  to securities in  which
the Portfolio may invest in order to implement regional allocation strategies or
to  hedge a  portion of the  Portfolio's investments. The  Portfolio will engage
only in transactions in  stock options and stock  index futures contracts  which
are traded on a recognized securities or futures exchange.
    
 
    The  Portfolio  may write  (i.e., sell)  covered  call options  on portfolio
securities which give  the purchaser the  right to buy  the underlying  security
covered  by  the option  from  the Portfolio  at  the stated  exercise  price. A
"covered" call option means that  so long as the  Portfolio is obligated as  the
writer  of the option, it will own  (i) the underlying securities subject to the
option, or (ii) securities  convertible or exchangeable  without the payment  of
any  consideration  into the  securities  subject to  the  option. By  selling a
covered call option, the Portfolio would become obligated during the term of the
option to deliver the securities underlying the option should the option  holder
choose  to exercise the  option before the option's  termination date. In return
for the call it has written, the  Portfolio will receive from the purchaser  (or
option  holder) a premium  which is the  price of the  option, less a commission
charged by a broker. The Portfolio  will keep the premium regardless of  whether
the  option is  exercised. When  the Portfolio  writes covered  call options, it
augments its income by the premiums received and is thereby hedged to the extent
of that amount against a decline in the price of the underlying securities.  The
premiums  received will offset a  portion of the potential  loss incurred by the
Portfolio if the securities  underlying the options are  ultimately sold by  the
Portfolio  at a loss. However,  during the option period,  the Portfolio has, in
return for  the premium  on the  option, given  up the  opportunity for  capital
appreciation  above the exercise price should the market price of the underlying
security increase, but has  retained the risk  of loss should  the price of  the
underlying  security decline. As a matter of  operating policy, the value of the
underlying securities on  which stock options  will be written  at any one  time
will not exceed 5% of the Portfolio's total assets.
 
    The  Portfolio may also write (i.e., sell) covered put options. Generally, a
put option  is  "covered"  if  the Portfolio  maintains  cash,  U.S.  Government
securities  or other high grade debt obligations  equal to the exercise price of
the option  or if  the  Portfolio holds  a put  option  on the  same  underlying
security  with a  similar or  higher exercise  price. By  selling a  covered put
option, the Portfolio incurs  an obligation to buy  the security underlying  the
option  from the purchaser of the put at the option's exercise price at any time
during the option period, at  the purchaser's election (certain options  written
by  the Portfolio will be exercisable by the purchaser only on a specific date).
The Portfolio may sell  put options to receive  the premiums paid by  purchasers
and  to close  out a  long put  option position.  In addition,  when the Adviser
wishes to purchase a security  at a price lower  than its current market  price,
the Portfolio may write a covered put option at an exercise price reflecting the
lower purchase price sought.
 
    The Portfolio may also purchase put or call options on individual securities
or baskets of securities. When the Portfolio purchases a call option it acquires
the   right  to   buy  a  designated   security  at  a   designated  price  (the
 
                                       13
<PAGE>
   
"exercise price"), and when the Portfolio purchases a put option it acquires the
right to sell a designated  security at the exercise price,  in each case on  or
before  a specified  date (the "termination  date"), usually not  more than nine
months from  the date  the option  is issued.  The Portfolio  may purchase  call
options  to close out a covered call  position or to protect against an increase
in the price of a security it anticipates purchasing. The Portfolio may purchase
put options on  securities which  it holds in  its portfolio  to protect  itself
against  a decline in the value of the  security. If the value of the underlying
security were to fall below the exercise price of the put purchased in an amount
greater than  the premium  paid for  the option,  the Portfolio  would incur  no
additional  loss.  The Portfolio  may  also purchase  put  options to  close out
written put  positions in  a  manner similar  to  call option  closing  purchase
transactions.
    
 
   
    The  primary  risks associated  with the  use of  options are  (i) imperfect
correlation between the  change in market  value of the  securities held by  the
Portfolio and the prices of options relating to the securities purchased or sold
by  the Portfolio; and  (ii) possible lack  of a liquid  secondary market for an
option. In the  opinion of  the Adviser,  the risk  that the  Portfolio will  be
unable  to close out an options contract will be minimized by only entering into
options transactions for which there appears to be a liquid secondary market.
    
 
   
    The Portfolio may purchase and sell  stock index futures contracts. A  stock
index  futures contract is an agreement to take or make delivery of an amount of
cash equal to the difference between the value of the index at the beginning and
at the end of the contract period. The Portfolio may utilize stock index futures
contracts in order to hedge against fluctuations  in the price of a security  it
holds  or intends to acquire, to remain fully invested and to reduce transaction
costs, but not  for speculation  or for  achieving leverage.  The Portfolio  may
enter  into stock index futures contracts provided  that not more than 5% of the
Portfolio's total assets at the time of entering into the contract or option  is
required  as deposit to secure obligations under such contracts and options, and
provided that not more than 20% of the Portfolio's total assets in the aggregate
is invested in stock index futures contracts.
    
 
   
    WHEN-ISSUED AND DELAYED  DELIVERY SECURITIES.   The  Portfolio may  purchase
securities  on a  when-issued or delayed  delivery basis.  In such transactions,
instruments are bought with payment and  delivery taking place in the future  in
order  to secure what is considered to be  an advantageous yield or price at the
time of the transaction. Delivery of  and payment for these securities may  take
as  long as a month or  more after the date of  the purchase commitment but will
take place  no more  than 120  days after  the trade  date. The  Portfolio  will
maintain  with the custodian  a separate account with  a segregated portfolio of
high-grade debt securities or  equity securities or cash  in an amount at  least
equal  to these commitments. The payment  obligation and the interest rates that
will be  received are  each fixed  at the  time the  Portfolio enters  into  the
commitment  and no interest accrues to  the Portfolio until settlement. Thus, it
is possible that the market value at  the time of settlement could be higher  or
lower  than the  purchase price  if, among other  factors, the  general level of
interest rates has changed. It is a current policy of the Portfolio not to enter
into when-issued commitments exceeding in the aggregate 15% of the market  value
of  the Portfolio's  total assets less  liabilities, other  than the obligations
created by these commitments.
    
 
                                       14
<PAGE>
                             INVESTMENT LIMITATIONS
 
    The International Magnum Portfolio  is a non-diversified investment  company
under  the 1940 Act, which  means that the Portfolio is  not limited by the 1940
Act in  the  proportion  of  its  total assets  that  may  be  invested  in  the
obligations  of  a  single issuer.  Thus,  the  Portfolio may  invest  a greater
proportion of its total assets in the securities of a smaller number of  issuers
and, as a result, will be subject to greater risk with respect to its respective
portfolio  securities.  The  Portfolio,  however,  intends  to  comply  with the
diversification requirements imposed by  the Internal Revenue  Code of 1986,  as
amended, for qualification as regulated investment companies. See "Taxes."
 
   
    The  Portfolio also operates under  certain investment restrictions that are
deemed fundamental limitations and may be changed only with the approval of  the
holders  of a  majority of the  Portfolio's outstanding  shares. See "Investment
Limitations" in  the  Statement  of Additional  Information.  In  addition,  the
Portfolio  operates  under  certain  non-fundamental  investment  limitations as
described below and in  the Statement of  Additional Information. The  Portfolio
may  not  (i) enter  into repurchase  agreements  with more  than seven  days to
maturity if, as a result, more than  15% of the market value of the  Portfolio's
net assets would be invested in such repurchase agreements and other investments
for  which market  quotations are not  readily available or  which are otherwise
illiquid; (ii) borrow money,  except from banks  for extraordinary or  emergency
purposes,  and then only  in amounts up to  10% of the  value of the Portfolio's
total assets, taken  at cost at  the time of  borrowing; or purchase  securities
while  borrowings  exceed 5%  of  its total  assets;  (iii) mortgage,  pledge or
hypothecate any assets except in connection  with any such borrowing in  amounts
up  to 10% of the value of the  Portfolio's net assets at the time of borrowing;
(iv) invest in fixed time deposits with a duration of over seven calendar  days;
or  (v) invest in fixed time deposits with  a duration of from two business days
to seven calendar days if more than 10% of the Portfolio's total assets would be
invested in these deposits.
    
 
   
                             MANAGEMENT OF THE FUND
    
 
   
    INVESTMENT ADVISER.  Morgan Stanley Asset Management Inc. is the  Investment
Adviser  and Administrator of the  Fund and each of  its portfolios. The Adviser
provides investment  advice and  portfolio management  services pursuant  to  an
Investment  Advisory Agreement  and, subject  to the  supervision of  the Fund's
Board  of  Directors,  makes  each  of  the  Portfolio's  day-to-day  investment
decisions,  arranges for the  execution of portfolio  transactions and generally
manages each of the Portfolio's investments. The Adviser is entitled to  receive
from  the  International  Magnum  Portfolio an  annual  management  fee, payable
quarterly, equal to 0.80% of the average daily net assets of the Portfolio.
    
 
    The fees of  the Portfolio,  which involves  international investments,  are
higher  than  those of  most  investment companies  but  comparable to  those of
investment companies  with  similar objectives.  The  Adviser has  agreed  to  a
reduction  in  the  fees  payable  to it  and  to  reimburse  the  Portfolio, if
necessary, if  such fees  would cause  total annual  operating expenses  of  the
Portfolio  to exceed 1.00% of the average daily net assets of the Class A shares
of the Portfolio and 1.25% of the average daily net assets of the Class B shares
of the Portfolio.
   
    The Adviser, with  principal offices  at 1221  Avenue of  the Americas,  New
York,  New  York  10020,  conducts a  worldwide  portfolio  management business,
providing a broad  range of portfolio  management services to  customers in  the
United  States  and abroad,  including investment  advisory services  to several
open-end investment  companies  and  many closed-end  investment  companies.  At
December 31, 1995, the Adviser, together with
    
 
                                       15
<PAGE>
its   affiliated  asset  management   companies,  managed  investments  totaling
approximately $57.4 billion, including approximately $41.9 billion under  active
management  and  $15.5  billion as  Named  Fiduciary or  Fiduciary  Adviser. See
"Management of the Fund" in the Statement of Additional Information.
 
    PORTFOLIO MANAGER.  FRANCINE J.  BOVICH. Francine Bovich joined the  Adviser
as  a  Principal  in  1993.  She is  responsible  for  portfolio  management and
communication of  the  Adviser's  asset  allocation  strategy  to  institutional
investor  clients. Previously,  Ms. Bovich  was a  Principal and  Executive Vice
President of  Westwood Management  Corp. ("Westwood"),  a registered  investment
adviser.  Before  joining  Westwood, she  was  a Managing  Director  of Citicorp
Investment Management, Inc. (now Chancellor  Capital Management), where she  was
responsible  for the Institutional Investment Management group. Ms. Bovich began
her investment career with Banker's Trust Company. She holds a B.A. in Economics
from Connecticut College and an M.B.A. in Finance from New York University.
 
    ADMINISTRATOR.   The  Adviser also  provides  the Fund  with  administrative
services  pursuant to an  Administration Agreement. The  services provided under
the Administration Agreement are subject to the supervision of the Officers  and
the  Board of  Directors of  the Fund  and include  day-to-day administration of
matters related  to the  corporate existence  of the  Fund, maintenance  of  its
records, preparation of reports, supervision of the Fund's arrangements with its
custodian   and  assistance  in  the  preparation  of  the  Fund's  registration
statements under  federal  and state  laws.  The Administration  Agreement  also
provides  that  the Administrator,  through its  agents,  will provide  the Fund
dividend disbursing  and transfer  agent services.  For its  services under  the
Administration  Agreement, the Fund pays  the Adviser a monthly  fee which on an
annual basis equals 0.15% of the average daily net assets of the Portfolio.
 
   
    Under an agreement between  the Adviser and The  Chase Manhattan Bank,  N.A.
("Chase"),  Chase provides  certain administrative  services to  the Fund.  In a
merger completed on September 1, 1995, Chase succeeded to all of the rights  and
obligations  under the U.S.  Trust Administration Agreement  between the Adviser
and the United  States Trust  Company of New  York ("U.S.  Trust"), pursuant  to
which  U.S. Trust had  agreed to provide certain  administrative services to the
Fund.  Pursuant  to  a  delegation  clause  in  the  U.S.  Trust  Administration
Agreement,  U.S. Trust  delegated its  administration responsibilities  to Chase
Global Funds Services Company ("CGFSC"), formerly known as Mutual Funds  Service
Company,  which after the  merger with Chase  is a subsidiary  of Chase and will
continue to provide  certain administrative  services to the  Fund. The  Adviser
supervises  and  monitors such  administrative services  provided by  CGFSC. The
services  provided  under  the  Administration  Agreement  and  the  U.S.  Trust
Administration  Agreement are  also subject to  the supervision of  the Board of
Directors of the  Fund. The  Board of  Directors of  the Fund  has approved  the
provision  of services described above  pursuant to the Administration Agreement
and the U.S. Trust  Administration Agreement as being  in the best interests  of
the  Fund. CGFSC's business address is  73 Tremont Street, Boston, Massachusetts
02108-3913. For additional information regarding the Administration Agreement or
the U.S. Trust  Administration Agreement, see  "Management of the  Fund" in  the
Statement of Additional Information.
    
 
    DIRECTORS  AND OFFICERS.  Pursuant to  the Fund's Articles of Incorporation,
the Board of Directors  decides upon matters of  general policy and reviews  the
actions  of the Fund's  Adviser, Administrator and  Distributor. The Officers of
the Fund conduct and supervise its daily business operations.
 
                                       16
<PAGE>
   
    DISTRIBUTOR.   Morgan Stanley  serves as  the exclusive  Distributor of  the
shares  of  the Fund.  Under its  Distribution Agreement  with the  Fund, Morgan
Stanley sells shares of the Portfolio upon the terms and at the current offering
price described in this Prospectus. Morgan Stanley is not obligated to sell  any
certain number of shares of the Fund.
    
 
   
    The  Portfolio currently offers  only the classes of  shares offered by this
Prospectus. The Portfolio may in the future offer one or more classes of  shares
with  features, distribution expenses or other  expenses that are different from
those of the classes currently offered.
    
 
    The Fund has  adopted a Plan  of Distribution  with respect to  the Class  B
shares  pursuant to Rule 12b-1 under the  1940 Act (the "Plan"). Under the Plan,
the Distributor is entitled  to receive from the  Portfolio a distribution  fee,
which  is accrued  daily and  paid quarterly,  of 0.25%  of the  Class B shares'
average daily net  assets on  an annualized  basis. The  Distributor expects  to
reallocate  most of its  fee to its  investment representatives. The Distributor
may, in its discretion, voluntarily waive from  time to time all or any  portion
of  its distribution fee and each of the  Distributor and the Adviser is free to
make additional payments  out of  its own  assets to  promote the  sale of  Fund
shares,   including   payments  that   compensate  financial   institutions  for
distribution services or shareholder services.
 
   
    The Plan is designed to compensate the Distributor for its services, not  to
reimburse  the Distributor for its expenses,  and the Distributor may retain any
portion of the fee that it does not expend in fulfillment of its obligations  to
the Fund.
    
 
   
    EXPENSES.   The Portfolio  is responsible for payment  of certain other fees
and expenses  (including  legal  fees, accountants'  fees,  custodial  fees  and
printing  and mailing  costs) specified  in the  Administration and Distribution
Agreements.
    
 
   
                               PURCHASE OF SHARES
    
 
   
    Class A and Class B shares of the Portfolio may be purchased, without  sales
commission,  at the net asset  value per share next  determined after receipt of
the purchase order by the Portfolio. See "Valuation of Shares."
    
 
   
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
    
 
   
    For a Portfolio account, the minimum initial investment and minimum  account
size  are $500,000 for Class  A shares and $100,000  for Class B shares. Managed
Accounts may  purchase Class  A shares  without being  subject to  such  minimum
initial investment or minimum account size requirements for a Portfolio account.
Officers  of the Adviser  and its affiliates  are subject to  the minimums for a
Portfolio account, except they may purchase Class B shares subject to a  minimum
initial investment and minimum account size of $5,000 for a Portfolio account.
    
 
   
    If  the value of a  Portfolio account containing Class  A shares falls below
$500,000  (but   remains  at   or  above   $100,000)  because   of   shareholder
redemption(s),  the Fund will  notify the shareholder, and  if the account value
remains below  $500,000 (but  remains at  or above  $100,000) for  a  continuous
60-day period, the Class A shares in such account will convert to Class B shares
and will be subject to the distribution fee and other features applicable to the
Class  B shares. The Fund,  however, will not convert Class  A shares to Class B
shares based
    
 
                                       17
<PAGE>
   
solely upon changes in  the market that  reduce the net  asset value of  shares.
Under current tax law, conversions between share classes are not a taxable event
to  the shareholder. Managed Accounts are not subject to conversion from Class A
shares to Class B shares.
    
 
   
    Investors may also invest in the  Fund by purchasing shares through a  trust
department, broker, dealer, agent, financial planner, financial services firm or
investment  adviser.  An  investor  may  be  charged  an  additional  service or
transaction fee by that institution. The minimum investment levels may be waived
at the discretion  of the  Adviser for (i)  certain employees  and customers  of
Morgan  Stanley  or  its  affiliates  and  certain  trust  departments, brokers,
dealers, agents,  financial planners,  financial services  firms, or  investment
advisers  that  have  entered  into  an agreement  with  Morgan  Stanley  or its
affiliates; and (ii) retirement and deferred compensation plans and trusts  used
to  fund such  plans, including,  but not limited  to, those  defined in Section
401(a), 403(b) or  457 of the  Internal Revenue  Code of 1986,  as amended,  and
"rabbi trusts".
    
 
   
    The  Fund reserves the right to  modify or terminate the conversion features
of the shares as stated above at any time upon 60 days' notice to shareholders.
    
 
   
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
    
 
   
    If the  value  of  a  Portfolio account  falls  below  $100,000  because  of
shareholder  redemption(s), the  Fund will  notify the  shareholder, and  if the
account value remains below $100,000 for a continuous 60-day period, the  shares
in  such account are subject to redemption by the Fund and, if redeemed, the net
asset value of such shares will be  promptly paid to the shareholder. The  Fund,
however,  will not redeem  shares based solely  upon changes in  the market that
reduce the net asset value of shares.
    
 
   
    For purposes of redemptions by the Fund, the foregoing minimum account  size
requirements  do not apply to Portfolio  accounts containing Class B shares held
by officers of  the Adviser or  its affiliates.  However, if the  value of  such
account  held by an officer of the  Adviser or its affiliates falls below $5,000
because of shareholder redemption(s), the Fund will notify the shareholder,  and
if  the account value remains $5,000 for  a continuous 60-day period, the shares
in such account are subject to redemption by the Fund and, if redeemed, the  net
asset  value of such  shares will be  promptly paid to  the shareholder. Managed
Accounts are not subject to involuntary redemption.
    
 
   
    The  Fund  reserves  the  right  to  modify  or  terminate  the  involuntary
redemption  features of  the shares as  stated above  at any time  upon 60 days'
notice to shareholders.
    
 
   
CONVERSION FROM CLASS B TO CLASS A SHARES
    
 
   
    If the value of Class B shares in a Portfolio account increases, whether due
to shareholder share  purchases or  market activity,  to $500,000  or more,  the
Class  B shares  will convert  to Class  A shares.  Under current  tax law, such
conversion is not a taxable event  to the shareholder. Class A shares  converted
from  Class B shares are  subject to the same  minimum account size requirements
that are applicable to Portfolio accounts  containing Class A shares, as  stated
above.  The  Fund reserves  the  right to  modify  or terminate  this conversion
feature at any time upon 60 days' notice to shareholders.
    
 
   
INITIAL PURCHASES DIRECTLY FROM THE FUND
    
 
   
    The Fund's determination of an investor's eligibility to purchase shares  of
a  given class will  take precedence over  the investor's selection  of a class.
Assuming the investor is eligible for the  class, the Fund will select the  most
favorable class for the investor, if the investor has not done so.
    
 
                                       18
<PAGE>
INITIAL INVESTMENTS
 
1) BY  CHECK.   An account may  be opened  by completing and  signing an Account
   Registration Form and mailing it, together with a check ($500,000 minimum for
   Class A  shares of  the Portfolio  and $100,000  for Class  B shares  of  the
   Portfolio,  with certain exceptions  for Morgan Stanley  employees and select
   customers)  payable   to  "Morgan   Stanley  Institutional   Fund,  Inc.   --
   International Magnum Portfolio", to:
 
      Morgan Stanley Institutional Fund, Inc.
      P.O. Box 2798
      Boston, Massachusetts 02208-2798
   
  Payment  will  be accepted  only in  U.S. dollars,  unless prior  approval for
  payment by other currencies is given by  the Fund. The Class(es) of shares  of
  the Portfolio to be purchased should be designated on the Account Registration
  Form.  For purchases  by check, the  Fund is ordinarily  credited with Federal
  Funds within  one business  day. Thus  your  purchase of  shares by  check  is
  ordinarily  credited to your account  at the net asset  value per share of the
  Portfolio determined on the next business day after receipt.
    
 
2) BY FEDERAL  FUNDS WIRE.   Purchases  may be  made by  having your  bank  wire
   Federal  Funds to the Fund's bank account.  In order to ensure prompt receipt
   of your Federal Funds Wire, it is important that you follow these steps:
 
   
A.  Telephone the  Fund (toll  free: 1-800-548-7786)  and provide  us with  your
    name,  address,  telephone  number, Social  Security  or  Tax Identification
    Number, the  portfolio(s) selected,  the class  selected, the  amount  being
    wired,  and by  which bank.  We will  then provide  you with  a Fund account
    number. (Investors with existing accounts should also notify the Fund  prior
    to wiring funds.)
    
 
   
B.  Instruct  your  bank  to  wire  the  specified  amount  to  the  Fund's Wire
    Concentration Bank Account (be  sure to have your  bank include the name  of
    the  portfolio(s)  selected,  the  class  selected  and  the  account number
    assigned to you) as follows:
    
 
   
    Chase Manhattan Bank, N.A.
    One Manhattan Plaza
    New York, NY 10081-1000
    ABA #021000021
    DDA #910-2-733293
    Attn: Morgan Stanley Institutional Fund, Inc.
    Ref: (Portfolio name, your account number, your account name)
    
 
Please call the Fund at 1-800-548-7786 prior to wiring funds.
 
C.  Complete and sign the Account Registration  Form and mail it to the  address
    shown thereon.
 
   
  Purchase  orders for shares of  the Portfolio which are  received prior to the
  regular close of the NYSE (currently 4:00 p.m. Eastern Time) will be  executed
  at  the price computed  on the date of  receipt as long  as the Transfer Agent
  receives payment by check or  in Federal Funds prior  to the regular close  of
  the NYSE on such day.
    
 
                                       19
<PAGE>
   
  Federal Funds purchase orders will be accepted only on a day on which the Fund
  and Chase (the "Custodian Bank") are open for business. Your bank may charge a
  service fee for wiring Federal Funds.
    
 
3) BY  BANK WIRE.   The  same procedure outlined  under "By  Federal Funds Wire"
   above must be  followed in  purchasing shares  by bank  wire. However,  money
   transferred  by bank wire may or may  not be converted into Federal Funds the
   same day, depending on the time the  money is received and the bank  handling
   the  wire. Prior to such conversion, an investor's money will not be invested
   and, therefore, will not be earning dividends. Your bank may charge a service
   fee for wiring funds.
 
ADDITIONAL INVESTMENTS
 
   
    You may  add to  your account  at any  time (minimum  additional  investment
$1,000,  except  for  automatic  reinvestment  of  dividends  and  capital gains
distributions for which there are no minimums) by purchasing shares at net asset
value by mailing a check to  the Fund (payable to "Morgan Stanley  Institutional
Fund, Inc. -- International Magnum Portfolio") at the above address or by wiring
monies  to the Custodian Bank as outlined  above. It is very important that your
account name, the  portfolio name  and the class  selected be  specified in  the
letter  or wire to assure  proper crediting to your  account. In order to ensure
that your wire orders are invested promptly, you are requested to notify one  of
the  Fund's representatives (toll-free  1-800-548-7786) prior to  the wire date.
Additional investments will be applied to purchase additional shares in the same
class held by a shareholder in a Portfolio account.
    
 
   
OTHER PURCHASE INFORMATION
    
 
   
    The purchase price of the Class A and Class B shares of the Portfolio is the
net asset value next determined after  the order is received. See "Valuation  of
Shares."  An order received  prior to the  close of the  New York Stock Exchange
("NYSE"), which is  currently 4:00 p.m.  Eastern Time, will  be executed at  the
price  computed on the date of receipt; an order received after the close of the
NYSE will be executed at the price computed on the next day the NYSE is open  as
long  as the Transfer Agent receives payment  by check or in Federal Funds prior
to the regular close of the NYSE on such day.
    
 
   
    Although the legal rights of Class A  and Class B shares will be  identical,
the  different expenses borne by  each class will result  in different net asset
values and dividends. The net  asset value of Class  B shares will generally  be
lower than the net asset value of Class A shares as a result of the distribution
expense  charged to Class B shares. It  is expected, however, that the net asset
value per share of the two classes  will tend to converge immediately after  the
recording  of dividends  which will  differ by  approximately the  amount of the
distribution expense accrual differential between the classes.
    
 
    In the interest  of economy and  convenience, and because  of the  operating
procedures  of the Fund, certificates representing  shares of the Portfolio will
not be issued. All shares  purchased are confirmed to  you and credited to  your
account  on the Fund's books  maintained by the Adviser  or its agents. You will
have  the  same  rights  and  ownership  with  respect  to  such  shares  as  if
certificates had been issued.
 
    To  ensure that checks are collected by the Fund, withdrawals of investments
made by check  are not presently  permitted until payment  for the purchase  has
been  received,  which may  take up  to eight  business days  after the  date of
purchase. As a condition  of this offering,  if a purchase  is cancelled due  to
nonpayment or
 
                                       20
<PAGE>
because your check does not clear, you will be responsible for any loss the Fund
or  its agents  incur. If  you are  already a  shareholder, the  Fund may redeem
shares from your account(s) to reimburse the Fund or its agents for any loss. In
addition, you may be prohibited or restricted from making future investments  in
the Fund.
 
   
    Investors  may  also invest  in the  Fund by  purchasing shares  through the
Distributor.
    
 
   
EXCESSIVE TRADING
    
 
   
    Frequent  trades  involving  either   substantial  portfolio  assets  or   a
substantial  portion of your  account or accounts controlled  by you can disrupt
management of a portfolio and raise its expenses. Consequently, in the  interest
of  all the stockholders  of the Portfolio and  the Portfolio's performance, the
Fund may in its discretion bar  a stockholder that engages in excessive  trading
of  shares of any class  of a portfolio from further  purchases of shares of the
Fund for an indefinite period. The  Fund considers excessive trading to be  more
than  one purchase and sale involving shares of the same class of a portfolio of
the Fund  within  any  120-day  period. As  an  example,  exchanging  shares  of
portfolios of the Fund as follows amounts to excessive trading: exchanging Class
A shares of Portfolio A for Class A shares of Portfolio B, then exchanging Class
A  shares of Portfolio B for Class A  shares of Portfolio C and again exchanging
Class A shares of Portfolio C for Class A shares of Portfolio B within a 120-day
period. Two  types  of transactions  are  exempt from  these  excessive  trading
restrictions:  (1) trades exclusively  between money market  portfolios; and (2)
trades done  in  connection  with  an asset  allocation  service,  such  as  TFM
Accounts, managed or advised by MSAM and/or any of its affiliates.
    
 
   
                              REDEMPTION OF SHARES
    
 
   
    You  may  withdraw all  or  any portion  of the  amount  in your  account by
redeeming shares at any time. Please note  that purchases made by check are  not
permitted to be redeemed until payment of the purchase has been collected, which
may  take up to eight business days after purchase. The Fund will redeem Class A
shares or Class B shares of the Portfolio at the next determined net asset value
of shares of the applicable class. On days that both the NYSE and the  Custodian
Bank  are open for business,  the net asset value per  share of the Portfolio is
determined at the  close of  trading of the  NYSE (currently  4:00 p.m.  Eastern
Time).  Shares of the Portfolio may be  redeemed by mail or telephone. No charge
is made for redemption.  Any redemption proceeds  may be more  or less than  the
purchase  price of  your shares  depending on,  among other  factors, the market
value of the investment securities held by the Portfolio.
    
 
   
BY MAIL
    
 
   
    The Portfolio will redeem its  Class A shares or Class  B shares at the  net
asset  value determined on the  date the request is  received, if the request is
received in "good  order" before  the regular close  of the  NYSE. Your  request
should  be addressed to Morgan Stanley  Institutional Fund, Inc., P.O. Box 2798,
Boston, MA 02208-2798,  except that  deliveries by overnight  courier should  be
addressed  to Morgan  Stanley Institutional Fund,  Inc., c/o  Chase Global Funds
Services Company, 73 Tremont Street, Boston, MA 02108-3913.
    
 
   
    "Good order"  means that  the  request to  redeem  shares must  include  the
following documentation:
    
 
   
             (a)  A letter of  instruction or a  stock assignment specifying the
class and  number of  shares or  dollar amount  to be  redeemed, signed  by  all
registered owners of the shares in the exact names in which they are registered;
    
 
            (b)  Any  required  signature  guarantees  (see  "Further Redemption
Information" below); and
 
                                       21
<PAGE>
             (c) Other supporting legal documents,  if required, in the case  of
estates,   trusts,  guardianships,  custodianships,  corporations,  pension  and
profit-sharing plans and other organizations.
 
    Shareholders who are uncertain of requirements for redemption should consult
with a Morgan Stanley Institutional Fund representative.
 
BY TELEPHONE
 
   
    Provided you have previously elected the Telephone Redemption Option on  the
Account  Registration  Form, you  can  request a  redemption  of your  shares by
calling the Fund  and requesting  the redemption proceeds  be mailed  to you  or
wired  to your bank.  Please contact one of  Morgan Stanley Institutional Fund's
representatives for further details. In times of drastic market conditions,  the
telephone  redemption option  may be difficult  to implement.  If you experience
difficulty in making a telephone redemption, your request may be made by mail or
overnight courier and will be implemented at the net asset value next determined
after it is received. Redemption requests sent to the Fund through express  mail
must  be mailed  to the  address of the  Dividend Disbursing  and Transfer Agent
listed under "General Information." The Fund and the Fund's transfer agent  (the
"Transfer  Agent")  will  employ  reasonable  procedures  to  confirm  that  the
instructions communicated  by telephone  are genuine.  These procedures  include
requiring the investor to provide certain personal identification information at
the  time an account is opened and prior to effecting each transaction requested
by telephone. In addition, all  telephone transaction requests will be  recorded
and   investors  may  be  required  to  provide  additional  telecopied  written
instructions regarding transaction requests. Neither  the Fund nor the  Transfer
Agent will be responsible for any loss, liability, cost or expense for following
instructions received by telephone that either of them reasonably believes to be
genuine.
    
 
    To  change the commercial  bank or account  designated to receive redemption
proceeds, a written  request must  be sent  to the  Fund at  the address  above.
Requests  to change the bank  or account must be  signed by each shareholder and
each signature must be guaranteed.
 
FURTHER REDEMPTION INFORMATION
 
    Normally the  Fund will  make payment  for all  shares redeemed  within  one
business  day of receipt  of the request, but  in no event  will payment be made
more than  seven days  after receipt  of  a redemption  request in  good  order.
However,  payments to investors  redeeming shares which  were purchased by check
will not be made until  payment for the purchase  has been collected, which  may
take up to eight days after the date of purchase. The Fund may suspend the right
of  redemption or postpone the date upon which redemptions are effected at times
when the NYSE is closed, or  under any emergency circumstances as determined  by
the Securities and Exchange Commission (the "Commission").
 
    If  the Board of  Directors determines that  it would be  detrimental to the
best interests of the  remaining shareholders of the  Portfolio to make  payment
wholly  or partly in cash, the Fund may  pay the redemption proceeds in whole or
in part by a distribution in-kind of securities held by the Portfolio in lieu of
cash   in    conformity   with    applicable    rules   of    the    Commission.
Distributions-in-kind  will be made in  readily marketable securities. Investors
may incur brokerage charges on the  sale of portfolio securities so received  in
payment of redemptions.
 
                                       22
<PAGE>
    To  protect  your account,  the Fund  and its  agents from  fraud, signature
guarantees are required for  certain redemptions to verify  the identity of  the
person  who has  authorized a redemption  from your account.  Please contact the
Fund for further  information. See "Redemption  of Shares" in  the Statement  of
Additional Information.
 
                              SHAREHOLDER SERVICES
   
EXCHANGE FEATURES
    
 
   
    You  may exchange  shares that you  own in  the Portfolio for  shares of any
other available  portfolio of  the  Fund (other  than the  International  Equity
Portfolio,  which is  closed to  new investors). In  exchanging for  shares of a
portfolio with more  than one  class, the  class of  shares you  receive in  the
exchange  will be determined in the same  manner as any other purchase of shares
and will not  be based  on the  class of  shares surrendered  for the  exchange.
Consequently,  the same minimum initial investment  and minimum account size for
determining the  class  of shares  received  in  the exchange  will  apply.  See
"Purchase  of Shares."  Shares of  the portfolios  may be  exchanged by  mail or
telephone. The privilege to exchange shares  by telephone is automatic and  made
available  without shareholder election. Before you make an exchange, you should
read the prospectus of the portfolio(s) in which you seek to invest. Because  an
exchange  transaction  is treated  as a  redemption followed  by a  purchase, an
exchange would be considered  a taxable event for  shareholders subject to  tax.
The  exchange privilege  is only available  with respect to  portfolios that are
registered for  sale  in  a  shareholder's  state  of  residence.  The  exchange
privilege  may be modified or  terminated by the Fund at  any time upon 60 days'
notice to shareholders.
    
   
BY MAIL
    
   
    In order to  exchange shares  by mail, you  should include  in the  exchange
request  the name,  class of  shares and  account number  of the  Portfolio, the
name(s) of the  portfolio(s) and class(es)  of shares into  which you intend  to
exchange  shares, and the signatures of all registered account holders. Send the
exchange request  to Morgan  Stanley Institutional  Fund, Inc.,  P.O. Box  2798,
Boston, Massachusetts 02208-2798.
    
   
BY TELEPHONE
    
   
    When  exchanging shares by  telephone, have ready the  name, class of shares
and account number of the Portfolio, the names of the portfolio(s) and class(es)
of shares into which you intend to exchange shares, your Social Security  number
or  Tax I.D. number, and your  account address. Requests for telephone exchanges
received prior  to  4:00 p.m.  (Eastern  Time) are  processed  at the  close  of
business  that  same day  based  on the  net  asset value  of  the class  of the
portfolios involved in the exchange of shares at the close of business. Requests
received after 4:00 p.m. are  processed the next business  day based on the  net
asset  value determined  at the  close of business  on such  day. For additional
information  regarding  responsibility  for   the  authenticity  of   telephoned
instructions, see "Redemption of Shares -- By Telephone" above.
    
   
TRANSFER OF REGISTRATION
    
   
    You  may transfer  the registration  of any of  your Fund  shares to another
person by writing  to Morgan Stanley  Institutional Fund, Inc.,  P.O. Box  2798,
Boston,  MA 02208-2798. As in the case  of redemptions, the written request must
be received in  good order  before any transfer  can be  made. Transferring  the
registration  of shares may affect  the eligibility of your  account for a given
class of the  Portfolio's shares  and may  result in  involuntary conversion  or
redemption of your shares. See "Purchase of Shares" above.
    
 
                                       23
<PAGE>
   
                              VALUATION OF SHARES
    
 
   
    The  net asset  value per  share of a  class of  shares of  the Portfolio is
determined by dividing the total market value of the Portfolio's investments and
other assets attributable to  such class, less  any liabilities attributable  to
such  class, by  the total  number of  outstanding shares  of such  class of the
Portfolio. Net  asset value  is  calculated separately  for  each class  of  the
Portfolio.  Net asset value per share is determined  as of the close of the NYSE
on each day  that the NYSE  is open  for business. Price  information on  listed
securities  is taken from  the exchange where the  security is primarily traded.
Securities listed on a U.S. securities exchange for which market quotations  are
available  are valued at the last quoted sale  price on the day the valuation is
made. Securities listed on a foreign exchange are valued at their closing price.
Unlisted securities and listed securities not  traded on the valuation date  for
which market quotations are not readily available are valued at a price within a
range not exceeding the current asked price nor less than the current bid price.
The  current bid  and asked  prices are  determined based  on the  bid and asked
prices quoted on such valuation date by reputable brokers.
    
 
    Bonds and other fixed income securities are valued according to the broadest
and most representative  market, which will  ordinarily be the  over-the-counter
market.  Net asset value includes interest  on fixed income securities, which is
accrued daily.  In addition,  bonds and  other fixed  income securities  may  be
valued on the basis of prices provided by a pricing service when such prices are
believed  to  reflect  the fair  market  value  of such  securities.  The prices
provided by a pricing service are determined without regard to bid or last  sale
prices,  but take into  account institutional size trading  in similar groups of
securities and any developments related  to the specific securities.  Securities
not  priced in this manner are valued at  the most recently quoted bid price, or
when securities exchange valuations are used, at the latest quoted sale price on
the day of valuation. If there is  no such reported sale, the latest quoted  bid
price will be used. Securities purchased with remaining maturities of 60 days or
less are valued at amortized cost, if it approximates market value. In the event
that  amortized  cost  does  not  approximate  market  value,  market  prices as
determined above will be used.
 
   
    The value of other assets and securities for which no quotations are readily
available (including  restricted  and  unlisted foreign  securities)  and  those
securities  for which it is inappropriate to determine prices in accordance with
the above-stated procedure  are determined  in good  faith at  fair value  using
methods  determined by the  Board of Directors. For  purposes of calculating net
asset value per share, all assets and liabilities initially expressed in foreign
currencies will be translated into U.S. dollars at the mean of the bid price and
asked price of such currencies against the U.S. dollar last quoted by any  major
bank.
    
 
   
    Although  the legal rights of Class A  and Class B shares will be identical,
the different expenses borne  by each class will  result in different net  asset
values  and dividends for the class.  Dividends will differ by approximately the
amount of the distribution expense  accrual differential among the classes.  The
net  asset value of  Class B shares will  generally be lower  than the net asset
value of the Class A shares as  a result of the distribution expense charged  to
Class B shares.
    
 
   
                            PERFORMANCE INFORMATION
    
 
   
    The  Fund may from time to time advertise total return for each class of the
Portfolio. THESE FIGURES ARE BASED ON  HISTORICAL EARNINGS AND ARE NOT  INTENDED
TO INDICATE FUTURE PERFORMANCE. The "total return" shows what an investment in a
class  of the Portfolio would have earned  over a specified period of time (such
as one, five or ten years), assuming that all distributions and dividends by the
Portfolio were reinvested in the same class on the
    
 
                                       24
<PAGE>
   
reinvestment dates during the  period. Total return does  not take into  account
any  federal  or  state  income  taxes that  may  be  payable  on  dividends and
distributions  or  on  redemption.  The   Fund  may  also  include   comparative
performance information in advertising or marketing the Portfolio's shares. Such
performance  information may include data from Lipper Analytical Services, Inc.,
other industry publications,  business periodicals, rating  services and  market
indices.
    
 
   
    The  performance figures  for Class  B shares  will generally  be lower than
those for Class  A shares because  of the  distribution fee charged  to Class  B
shares.
    
 
   
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
    
 
   
    All  income dividends and capital gains  distributions for a class of shares
will automatically be reinvested in additional shares of such class at net asset
value, except that,  upon written  notice to  the Fund  or by  checking off  the
appropriate  box in the Distribution Option  Section on the Account Registration
Form, a shareholder  may elect  to receive  income dividends  and capital  gains
distributions  in cash. The Portfolio expects to distribute substantially all of
its net investment income in the  form of annual dividends. Net realized  gains,
if  any, after reduction for  any available tax loss  carryforwards will also be
distributed annually. Confirmations of the  purchase of shares of the  Portfolio
through  the  automatic  reinvestment  of  income  dividends  and  capital gains
distributions will be  provided, pursuant  to Rule 10b-10  under the  Securities
Exchange Act of 1934, as amended, on the next monthly client statement following
such  purchase of shares. Consequently, confirmations of such purchases will not
be provided at the time  of completion of such  purchases as might otherwise  be
required by Rule 10b-10.
    
 
   
    Undistributed  net  investment income  is  included in  the  Portfolio's net
assets for the purpose of calculating  net asset value per share. Therefore,  on
the  "ex-dividend" date,  the net  asset value  per share  excludes the dividend
(i.e., is  reduced by  the per  share amount  of the  dividend). Dividends  paid
shortly after the purchase of shares by an investor, although in effect a return
of capital, are taxable to shareholders subject to income tax.
    
 
   
    Because  of  the  distribution  fee  and  any  other  expenses  that  may be
attributable to  the Class  B shares,  the net  income attributable  to and  the
dividends  payable  on  Class  B  shares  will  be  lower  than  the  net income
attributable to and the dividends  payable on Class A  shares. As a result,  the
net  asset value per share of the classes of the Portfolio will differ at times.
Expenses of the Portfolio allocated to a particular class of shares thereof will
be borne on a pro rata basis by each outstanding share of that class.
    
 
   
                                     TAXES
    
 
   
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
    
 
   
    No attempt has been made to  present a detailed explanation of the  federal,
state,  or  local income  tax treatment  of the  Portfolio or  its shareholders.
Accordingly, shareholders  are urged  to consult  their tax  advisers  regarding
specific questions as to federal, state and local income taxes.
    
 
    The  Portfolio  is  treated as  a  separate  entity for  federal  income tax
purposes and is  not combined with  the Fund's other  portfolios. The  Portfolio
intends   to  qualify   for  the   special  tax   treatment  afforded  regulated
 
                                       25
<PAGE>
investment companies under Subchapter M of the Internal Revenue Code of 1986, as
amended (the "Code"), so that the  Portfolio will be relieved of federal  income
tax  on that  part of  its net investment  income and  net capital  gain that is
distributed to shareholders.
 
   
    The Portfolio distributes  substantially all  of its  net investment  income
(including,  for  this purpose,  net short-term  capital gain)  to shareholders.
Dividends from the Portfolio's net investment income are taxable to shareholders
as ordinary income, whether received in cash or reinvested in additional shares.
Such dividends paid  by the  Portfolio will generally  not qualify  for the  70%
dividends-received  deduction  for  corporate shareholders.  The  Portfolio will
report annually to its shareholders the amount of dividend income qualifying for
such treatment.
    
 
   
    Distributions of net  capital gains  (i.e., net long-term  capital gains  in
excess  of  net  short-term  capital  losses)  are  taxable  to  shareholders as
long-term capital gains,  regardless of how  long the shareholder  has held  the
Portfolio's  shares. The Portfolio sends reports annually to shareholders of the
federal income tax status of all distributions made during the preceding year.
    
   
    The  Portfolio   intends  to   make  sufficient   distributions  or   deemed
distributions  of its ordinary income and capital gain net income (the excess of
short-term and long-term  capital gains  over short-term  and long-term  capital
losses), including any available capital loss carryforwards, prior to the end of
each calendar year to avoid liability for federal excise tax.
    
 
   
    Dividends  and  other distributions  declared by  the Portfolio  in October,
November or December of any year and payable to shareholders of record on a date
in such month will be deemed to have been paid by the Portfolio and received  by
the  shareholders on December 31  of that year if  the distributions are paid by
the Portfolio at any time during the following January.
    
 
   
    The sale, exchange  or redemption of  shares may result  in taxable gain  or
loss to the selling, exchanging or redeeming shareholder, depending upon whether
the fair market value of the sale, exchange or redemption proceeds exceeds or is
less  than the shareholder's  adjusted basis in the  redeemed, exchanged or sold
shares. If capital gain distributions have been made with respect to shares that
are sold at a  loss after being held  for six months or  less, then the loss  is
treated  as  a  long-term  capital  loss  to  the  extent  of  the  capital gain
distributions.
    
 
    The conversion of Class A shares to  Class B shares should not be a  taxable
event to the shareholder.
 
    Shareholders  are urged  to consult with  their tax  advisers concerning the
application of state  and local income  taxes to investments  in the  Portfolio,
which may differ from the federal income tax consequences described above.
 
    Investment  income  received by  the Portfolio  from sources  within foreign
countries may be subject to foreign income taxes withheld at the source. To  the
extent  that the Portfolio is  liable for foreign income  taxes so withheld, the
Portfolio intends to operate so as to meet the requirements of the Code to  pass
through  to the shareholders credit for  foreign income taxes paid. Although the
Portfolio intends to  meet Code  requirements to  pass through  credit for  such
taxes, there can be no assurance that the Portfolio will be able to do so.
 
                                       26
<PAGE>
    THE   TAX  DISCUSSION  SET  FORTH  ABOVE  IS  INCLUDED  HEREIN  FOR  GENERAL
INFORMATION ONLY. PROSPECTIVE  INVESTORS SHOULD CONSULT  THEIR OWN TAX  ADVISERS
WITH RESPECT TO THE TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN THE PORTFOLIO.
 
                             PORTFOLIO TRANSACTIONS
 
    The  Investment  Advisory Agreement  authorizes  the Adviser  to  select the
brokers or  dealers that  will execute  the purchases  and sales  of  investment
securities  for the Portfolio and directs the Adviser to use its best efforts to
obtain the best available price and most favorable execution with respect to all
transactions for  the Portfolio.  The Fund  has authorized  the Adviser  to  pay
higher commissions in recognition of brokerage services which, in the opinion of
the Adviser, are necessary for the achievement of better execution, provided the
Adviser believes this to be in the best interest of the Fund.
 
   
    Since  shares of the Portfolio are not marketed through intermediary brokers
or dealers, it  is not the  Fund's practice to  allocate brokerage or  principal
business  on the basis of sales of shares  which may be made through such firms.
However, the Adviser  may place portfolio  orders with qualified  broker-dealers
who  recommend the  Fund's portfolios or  who act  as agents in  the purchase of
shares of the Fund's portfolios for their clients.
    
 
   
    In purchasing and  selling securities for  the Portfolio, it  is the  Fund's
policy to seek to obtain quality execution at the most favorable prices, through
responsible   broker-dealers.  In   selecting  broker-dealers   to  execute  the
securities transactions for the Portfolio,  consideration will be given to  such
factors  as the price of the security, the  rate of the commission, the size and
difficulty of  the  order,  the  reliability,  integrity,  financial  condition,
general  execution and operational capabilities of competing broker-dealers, and
the brokerage  and  research services  which  they  provide to  the  Fund.  Some
securities  considered for investment  by the Portfolio  may also be appropriate
for other  clients served  by the  Adviser. If  purchase or  sale of  securities
consistent  with the  investment policies  of the Portfolio  and one  or more of
these other clients served  by the Adviser  is considered at  or about the  same
time,  transactions in such securities will be allocated among the Portfolio and
clients in a manner deemed fair and reasonable by the Adviser. Although there is
no specified formula  for allocating such  transactions, the various  allocation
methods used by the Adviser, and the results of such allocations, are subject to
periodic review by the Fund's Board of Directors.
    
 
   
    Subject to the overriding objective of obtaining the best possible execution
of  orders, the  Adviser may  allocate a  portion of  each portfolio's brokerage
transactions to Morgan Stanley or broker affiliates of Morgan Stanley. In  order
for  Morgan Stanley or  its affiliates to effect  any portfolio transactions for
the Fund, the commissions, fees or other remuneration received by Morgan Stanley
or such affiliates must be reasonable and fair compared to the commissions, fees
or other  remuneration  paid to  other  brokers in  connection  with  comparable
transactions   involving  similar  securities  being  purchased  or  sold  on  a
securities exchange during a comparable  period of time. Furthermore, the  Board
of  Directors of  the Fund, including  a majority  of the Directors  who are not
"interested persons," as defined in the 1940 Act, have adopted procedures  which
are  reasonably  designed  to  provide  that  any  commissions,  fees  or  other
remuneration paid to Morgan Stanley or  such affiliates are consistent with  the
foregoing standard.
    
 
                                       27
<PAGE>
    Portfolio  securities will not be purchased from,  or through, or sold to or
through, the Adviser or Morgan Stanley  or any "affiliated persons," as  defined
in  the 1940 Act, of Morgan Stanley when such entities are acting as principals,
except to the extent permitted by law.
 
   
    Although the  Portfolio will  not invest  for short-term  trading  purposes,
investment securities may be sold from time to time without regard to the length
of  time they have been held. It is anticipated that the annual turnover rate of
the Portfolio will not exceed 100% in normal circumstances.
    
 
   
                              GENERAL INFORMATION
    
 
   
DESCRIPTION OF COMMON STOCK
    
 
   
    The Fund  was organized  as a  Maryland corporation  on June  16, 1988.  The
Articles  of Incorporation, as amended and restated, permit the Fund to issue up
to 34 billion shares of common stock,  with $.001 par value per share.  Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number  of shares the  Fund is authorized  to issue without  the approval of the
shareholders of the  Fund. Subject  to the  notice period  to shareholders  with
respect  to shares held by shareholders, the Board of Directors has the power to
designate one or  more classes of  shares of  common stock and  to classify  and
reclassify  any  unissued shares  with respect  to such  classes. The  shares of
common stock of each  portfolio are currently classified  into two classes,  the
Class  A shares and the Class B  shares, except for the International Small Cap,
Money Market and  Municipal Money Market  Portfolios, which only  offer Class  A
shares.
    
 
   
    The shares of the Portfolio, when issued, will be fully paid, nonassessable,
fully  transferable and redeemable at the option  of the holder. The shares have
no preference  as  to  conversion,  exchange,  dividends,  retirement  or  other
features  and  have  no preemptive  rights.  The  shares of  the  Portfolio have
non-cumulative voting rights, which means that  the holders of more than 50%  of
the  shares voting for the election of Directors can elect 100% of the Directors
if they choose  to do so.  Persons or organizations  owning 25% or  more of  the
outstanding  shares of the Portfolio may be  presumed to "control" (as that term
is defined in the 1940 Act) the  Portfolio. Under Maryland law, the Fund is  not
required  to hold an annual meeting of its shareholders unless required to do so
under the 1940 Act.
    
 
REPORTS TO SHAREHOLDERS
 
    The Fund will send to its  shareholders annual and semi-annual reports;  the
financial  statements  appearing in  annual reports  are audited  by independent
accountants. Monthly unaudited portfolio  data is also  available from the  Fund
upon request.
 
   
    In  addition, the Adviser or its agent, as Transfer Agent, will send to each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
    
 
   
CUSTODIAN
    
 
   
    As of September  1, 1995, domestic  securities and cash  are held by  Chase,
which  replaced U.S.  Trust as  the Fund's domestic  custodian. Chase  is not an
affiliate of  the Adviser  or  the Distributor.  Morgan Stanley  Trust  Company,
Brooklyn,  New York ("MSTC"),  an affiliate of the  Adviser and the Distributor,
acts as the Fund's custodian for  foreign assets held outside the United  States
and  employs subcustodians  approved by  the Board of  Directors of  the Fund in
accordance with regulations of  the Securities and  Exchange Commission for  the
    
 
                                       28
<PAGE>
   
purpose  of providing  custodial services  for such  assets. MSTC  may also hold
certain domestic assets for  the Fund. For more  information on the  custodians,
see "General Information -- Custody Arrangements" in the Statement of Additional
Information.
    
 
   
DIVIDEND DISBURSING AND TRANSFER AGENT
    
 
   
    Chase   Global   Funds  Services   Company,   73  Tremont   Street,  Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
    
 
   
INDEPENDENT ACCOUNTANTS
    
 
   
    Price Waterhouse  LLP serves  as independent  accountants for  the Fund  and
audits its annual financial statements.
    
 
   
LITIGATION
    
 
   
    The Fund is not involved in any litigation.
    
 
                                       29
<PAGE>
<TABLE>
<CAPTION>
   
   MORGAN STANLEY INSTITUTIONAL FUND, INC.
          INTERNATIONAL MAGNUM PORTFOLIO
          P.O. BOX 2798, BOSTON, MA 02208-2798
    
   



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                           ACCOUNT REGISTRATION FORM
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<S>                        <C>
ACCOUNT INFORMATION        If you need assistance in filling out this form     
Fill in where applicable   for the Morgan Stanley Institutional Fund, please   
                           contact your Morgan Stanley representative or call  
                           us toll free 1 (800) 548-7786. Please print all     
                           items except signature, and mail to the Fund at the
                           address above.

- ---------------------------------------------------------------------------------------------------------------
A)  REGISTRATION
    1. INDIVIDUAL            1. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
                                 First Name           Initial              Last Name
    2. JOINT TENANTS         2. / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       (RIGHTS OF                First Name           Initial              Last Name
       SURVIVORSHIP            / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       PRESUMED UNLESS           First Name           Initial              Last Name
       TENANCY IN COMMON 
       IS INDICATED)      
- ---------------------------------------------------------------------------------------------------------------

    3. CORPORATIONS,        3.  / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       TRUSTS AND OTHERS       
       Please call the          / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       Fund for additional
       documents that may       / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / /
       be required to set 
       up account and to 
       authorize transactions
                                Type of / / INCORPORATED / / UNINCORPORATED / / PARTNERSHIP / / UNIFORM GIFT/TRANSFER TO MINOR 
                                Registration:                 ASSOCIATION                   (ONLY ONE CUSTODIAN AND MINOR PERMITTED)


                                / / TRUST __________________________________     / / OTHER (Specify) ______________________________
    
- ---------------------------------------------------------------------------------------------------------------
B)  MAILING ADDRESS         Street or P.O. Box / / / / / / / / / / / / / / / / / / / / / / / / / / / /

    Please fill in 
    completely, including   City / / / / / / / / / / / / / State / / / Zip / / / / / /-/ / / / / / / / 
    telephone number(s).
                            Home                                   Business
                            Telephone No./ / / /-/ / / /-/ / / / / Telephone No./ / / /-/ / / /-/ / / /
                            / / United States  / / Resident  / /Non-Resident Alien:
                                Citizen            Alien        Indicate Country of Residence _________
- ---------------------------------------------------------------------------------------------------------------
C)  TAXPAYER                PART 1. Enter your Taxpayer            IMPORTANT TAX INFORMATION 
    IDENTIFICATION          Identification Number. For most          You (as a payee) are required by
    NUMBER                  individual taxpayers, this is your     law to provide us (as payer) with
    If the account is in    Social Security Number.                your correct Taxpayer Identification
    more than one name,     TAXPAYER IDENTIFICATION NUMBER         Number. Accounts that have a missing
    CIRCLE THE NAME OF THE    / / / /-/ / / / / / / / /            or incorrect Taxpayer Identification
    PERSON WHOSE TAXPAYER               OR                         Number will be subject to backup
    IDENTIFICATION NUMBER       SOCIAL SECURITY NUMBER             withholding at a 31% rate on dividends,
    IS PROVIDED IN SECTION    / / / /-/ / /-/ / / / /              distributions and other payments.
    A) ABOVE. If no name      PART 2. BACKUP WITHHOLDING           If you have not provided us with
    is circled, the number    / / Check this box if you are        your correct taxpayer identification
    will be considered to be  NOT subject to Backup                number, you may be subject to 
    that of the last name     Withholding under the                a $50 penalty imposed by the Internal
    listed. For Custodian     provisions of Section                Revenue Service.
    account of a minor        3406(a)(1)(C) of the Internal          Backup withholding is not an
    (Uniform Gift/Transfer    Revenue Code.                        additional tax; the tax liability of
    to Minor Act), give the                                        persons subject to backup withholding
    Social Security Number                                         will be reduced by the amount of tax
    of the minor.                                                  withheld. If withholding results in
                                                                   an overpayment of taxes, a refund 
                                                                   may be obtained. You may be notified
                                                                   that you are subject to backup 
                                                                   withholding under Section 3406(a)(1)(C)
                                                                   of the Internal Revenue Code because you
                                                                   have underreported interest or dividends
                                                                   or you were required to but failed to
                                                                   file a return which would have included a
                                                                   reportable interest or dividend payment. IF
                                                                   YOU HAVE NOT BEEN SO NOTIFIED, CHECK THE
                                                                   BOX IN PART 2 AT LEFT.

- ---------------------------------------------------------------------------------------------------------------
D)  PORTFOLIO AND          For Purchase of the following Portfolio:     
    CLASS SELECTION        International Magnum Portfolio              / / Class A Share ____ / / Class B Shares ____
    (Class A shares 
    minimum $500,000
    and Class B shares                                    Total Initial Investment $_____________
    minimum $100,000).
    Please indicate
    class and amount.
    

- ---------------------------------------------------------------------------------------------------------------
   
E)  METHOD OF   Payment by:
    INVESTMENT  / / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL 
                           FUND, INC.--INTERNATIONAL MAGNUM PORTFOLIO)
    Please          
    indicate
    manner of   / / Exchange $____________ From________________       / / / / / / / / / / /-/ /
    payment.                                Name of Portfolio              Account No.

               / / Account previously established by: 

               / / Phone exchange / / Wire on___________________       / / / / / / / / / / / /-/ /
                                                          Date             Account No.            (Check
                                                                 (Previously assigned by the Fund) Digit)
    

<PAGE>

   
- ---------------------------------------------------------------------------------------------------------------

F)  DISTRIBUTION                                       Income dividends and capital gains distributions (if any) will
    OPTION                                             be reinvested in additional shares unless either box below is
                                                       checked.
                                                       / / Income dividends to be paid in cash, capital
                                                           gains distributions (if any) in shares.

                                                      / /  Income dividends and capital gains distributions
                                                           (if any) to be paid in cash.

- ---------------------------------------------------------------------------------------------------------------

G)  TELEPHONE                    / / I/we hereby authorize the Fund and its      ______________________   ________________
    REDEMPTION                       agents to honor any telephone requests      Name of COMMERCIAL Bank  Bank Account No.
    OPTION                           to wire redemption proceeds to the            (Not Savings Bank)
    Please select at time of         commercial bank indicated at right and/or 
    initial application if you       mail redemption proceeds to the name and                             ________________
    wish to redeem shares by         address in which my/our fund account is                                 Bank ABA No.
    telephone. A SIGNATURE           registered if such requests are believed 
    GUARANTEE IS REQUIRED IF         to be authentic.                           _________________________________________________
    BANK ACCOUNT IS NOT          The Fund and the Fund's D.S. Transfer Agent     Name(s) in which your BANK Account is Established
    REGISTERED IDENTICALLY TO    will employ reasonable procedures to confirm
    YOUR FUND ACCOUNT.           that instructions communicated by telephone are _________________________________________________
                                 genuine. These procedures include requiring                 Bank's Street Address
    TELEPHONE REQUESTS FOR       the investor to provide certain personal
    REDEMPTIONS OR EXCHANGES     identification information at the time an      _________________________________________________
    WILL NOT BE HONORED UNLESS   account is opened and prior to effecting each  City                    State                Zip
    THE BOX IS CHECKED.          transaction requested by telephone. In addition,
                                 all telephone transaction requests will be recorded
                                 and investors may be required to provide additional
                                 telecopied written instructions of transaction
                                 requests. Neither the Fund nor the Transfer Agent will
                                 be responsible for any loss, liability, cost or expense
                                 for following instructions received by telephone that
                                 it reasonably believes to be genuine.


- ---------------------------------------------------------------------------------------------------------------
H)  INTERESTED PARTY
    OPTION
    In addition to the account   _________________________________________________________________
    statement sent to my/our                                 Name
    registered address, I/we     _________________________________________________________________
    hereby authorize the fund    
    to mail duplicate            _________________________________________________________________
    statements to the name and                              Address
    address provided at right.
                                 _________________________________________________________________
                                  City                      State                     Zip Code

- ---------------------------------------------------------------------------------------------------------------
I)  DEALER 
    INFORMATION                  _______________________  _______________________________  ___________
                                 Representative Name          Representative No.             Branch No.

- ---------------------------------------------------------------------------------------------------------------

J)  SIGNATURE OF        The undersigned certify  that I/we  have full  authority and  legal
    ALL HOLDERS         capacity  to purchase and redeem shares of the Fund and affirm that I/we
    AND TAXPAYER        have received a current Prospectus  of the Morgan Stanley  Institutional
    CERTIFICATION       Fund,  Inc. and agree to  be bound by its  terms.
    Sign Here > 

                        (X)                                 (X)
                        __________________________________  ______________________________________
                        Signature                Date       Signature                  Date

- ---------------------------------------------------------------------------------------------------------------


    
</TABLE>

<PAGE>
                 (This page has been left blank intentionally.)
<PAGE>
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
 
  NO  DEALER, SALES  REPRESENTATIVE OR ANY  OTHER PERSON HAS  BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE  CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS  HAVING BEEN AUTHORIZED BY THE FUND  OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF  THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION  TO
ANY  PERSON TO WHOM  IT IS UNLAWFUL TO  MAKE SUCH OFFER  OR SOLICITATION IN SUCH
JURISDICTION.
 
                           --------------------------
 
                               TABLE OF CONTENTS
 
   
<TABLE>
<S>                                                 <C>
                                                    PAGE
                                                    ----
Fund Expenses.....................................    2
Prospectus Summary................................    4
Investment Objective and Policies.................    8
Additional Investment Information.................    9
Investment Limitations............................   15
Management of the Fund............................   15
Purchase of Shares................................   17
Redemption of Shares..............................   21
Shareholder Services..............................   23
Valuation of Shares...............................   24
Performance Information...........................   24
Dividends and Capital Gains Distributions.........   25
Taxes.............................................   25
Portfolio Transactions............................   27
General Information...............................   28
Account Registration Form
</TABLE>
    
 
                         INTERNATIONAL MAGNUM PORTFOLIO
 
                               A PORTFOLIO OF THE
 
                                 MORGAN STANLEY
 
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
 
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
 
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
                      P.O. BOX 2798, BOSTON, MA 02208-2798
 
- ---------------------------------------
- ---------------------------------------
- ---------------------------------------
- ---------------------------------------
<PAGE>

                     MORGAN STANLEY INSTITUTIONAL FUND, INC.
                       STATEMENT OF ADDITIONAL INFORMATION

   
     Morgan Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company with diversified and non-diversified series
("Portfolios").  The Fund currently consists of twenty-eight Portfolios offering
a broad range of investment choices.  The Fund is designed to provide clients
with attractive alternatives for meeting their investment needs.  Each
Portfolio, except the Money Market, Municipal Money Market, International Small
Cap and China Growth Portfolios, offers two classes of shares, the Class A
shares and the Class B shares (each, a "Multiclass Portfolio").  Each Multiclass
Portfolio, except the International Magnum Portfolio, offered one class of
shares until January 2, 1996, when all shares of such Portfolios owned prior to
January 2, 1996 were redesignated Class A shares.  The Class A shares and the
Class B shares currently offered by each Multiclass Portfolio have different
minimum investment requirements and fund expenses.  Shares of each Portfolio are
offered with no sales charge or exchange or redemption fee (with the exception
of the International Small Cap Portfolio).  This Statement of Additional
Information addresses information of the Fund applicable to each of the twenty-
eight Portfolios.

     This Statement is not a prospectus but should be read in conjunction with
the several prospectuses of the Fund's Portfolios (the "Prospectuses").  To
obtain any of the Prospectuses, please call the Morgan Stanley Institutional
Fund, Inc. Services Group at 1-800-548-7786.

                                TABLE OF CONTENTS

                                                                            PAGE
                                                                            ----
Investment Objectives and Policies . . . . . . . . . . . . . . . . . . . .     2
Taxes  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .    12
Special Tax Considerations Relating to Municipal Bond and
  Municipal Money Market Portfolios  . . . . . . . . . . . . . . . . . . .    14
Special Tax Considerations Relating to Foreign Investments . . . . . . . .    15
Taxes and Foreign Shareholders . . . . . . . . . . . . . . . . . . . . . .    16
Purchase of Shares . . . . . . . . . . . . . . . . . . . . . . . . . . . .    16
Redemption of Shares . . . . . . . . . . . . . . . . . . . . . . . . . . .    16
Shareholder Services . . . . . . . . . . . . . . . . . . . . . . . . . . .    17
Investment Limitations . . . . . . . . . . . . . . . . . . . . . . . . . .    18
Determining Maturities of Certain Instruments. . . . . . . . . . . . . . .    19
Management of the Fund . . . . . . . . . . . . . . . . . . . . . . . . . .    20
Net Asset Value for Money Market Portfolios. . . . . . . . . . . . . . . .    29
Performance Information. . . . . . . . . . . . . . . . . . . . . . . . . .    30
General Information. . . . . . . . . . . . . . . . . . . . . . . . . . . .    37
Description of Securities and Ratings. . . . . . . . . . . . . . . . . . .    37
Financial Statements . . . . . . . . . . . . . . . . . . . . . . . . . . .    43

STATEMENT OF ADDITIONAL INFORMATION DATED MAY 1, 1996, RELATING TO:

     Prospectus for the International Magnum Portfolio, dated May 1, 1996

     Prospectus for the U.S. Real Estate Portfolio, dated May 1, 1996

     Prospectus for the Fixed Income Portfolio, Global Fixed Income Portfolio,
     Municipal Bond Portfolio, Mortgage-Backed Securities Portfolio, High Yield
     Portfolio, Money Market Portfolio and Municipal Money Market Portfolio,
     dated May 1, 1996

     Prospectus for the Equity Growth Portfolio, Emerging Growth Portfolio,
     MicroCap Portfolio and Aggressive Equity Portfolio, dated May 1, 1996

     Prospectus for the Small Cap Value Equity Portfolio, Value Equity Portfolio
     and Balanced Portfolio, dated May 1, 1996

     Prospectus for the Global Equity Portfolio, International Equity Portfolio,
     International Small Cap Portfolio, Asian Equity Portfolio, European Equity
     Portfolio, Japanese Equity Portfolio and Latin American Portfolio, dated
     May 1, 1996

     Prospectus for the Emerging Markets Portfolio and Emerging Markets Debt
     Portfolio, dated May 1, 1996

     Prospectus for the Active Country Allocation Portfolio, dated May 1, 1996

     Prospectus for the Gold Portfolio, dated May 1, 1996

     Prospectus for the China Growth Portfolio, dated April 13, 1994
    


<PAGE>

                       INVESTMENT OBJECTIVES AND POLICIES

     The following policies supplement the investment objectives and policies
set forth in the Fund's Prospectuses:

CURRENCY SWAPS

   
     The China Growth Portfolio may enter into currency swaps for hedging
purposes and non-hedging purposes.  Inasmuch as swaps are entered into for good
faith hedging purposes and are offset by a segregated account as described
below, the Portfolio believes that swaps do not constitute senior securities as
defined in the 1940 Act and, accordingly, will not treat them as being subject
to the Portfolio's borrowing restrictions.  An amount of cash or liquid high
grade debt securities (i.e., securities rated in one of the top three ratings
categories by Moody's Investors Service, Inc. ("Moody's") or Standard & Poor's
Ratings Group ("S&P"), or, if unrated, deemed by the Adviser to be of comparable
credit quality) having an aggregate net asset value at least equal to the gross
payments which the Portfolio is obligated to make under the currency swap will
be maintained in a segregated account by the Fund's Custodian.  The Portfolio
will not enter into any currency swap unless the credit quality of the unsecured
senior debt or the claims-paying ability of the other party thereto is
considered to be investment grade by the Adviser.  If there is a default by the
other party to such a transaction, the Portfolio will have contractual remedies
pursuant to the agreements related to the transaction.  The swap market has
grown substantially in recent years with a large number of banks and investment
banking firms acting both as principals and as agents utilizing standardized
swap documentation.  As a result, the swap market has become relatively liquid
in comparison with the markets for other similar instruments which are traded in
the interbank market.
    

EMERGING COUNTRY EQUITY AND DEBT SECURITIES

GENERAL.  Each of the Emerging Markets and Emerging Markets Debt Portfolio's
definition of emerging country equity or debt securities includes securities of
companies that may have characteristics and business relationships common to
companies in a country or countries other than an emerging country. As a result,
the value of the securities of such companies may reflect economic and market
forces applicable to other countries, as well as to an emerging country.  Morgan
Stanley Asset Management Inc. (the "Adviser") believes, however, that investment
in such companies will be appropriate because the Portfolio will invest only in
those companies which, in its view, have sufficiently strong exposure to
economic and market forces in an emerging country such that their value will
tend to reflect developments in such emerging country to a greater extent than
developments in another country or countries.  For example, the Portfolio may
invest in companies organized and located in countries other than an emerging
country, including companies having their entire production facilities outside
of an emerging country, when securities of such companies meet one or more
elements of the Portfolio's definition of an emerging country equity or debt
security and so long as the Adviser believes at the time of investment that the
value of the company's securities will reflect principally conditions in such
emerging country.

     The Emerging Markets Debt Portfolio is subject to no restrictions on the
maturities of the emerging country debt securities it holds; those maturities
may range from overnight to 30 years.  The value of debt securities held by the
Portfolio generally will vary inversely to changes in prevailing interest rates.
The Portfolio's investments in fixed-rated debt securities with longer terms to
maturity are subject to greater volatility than the Portfolio's investments in
shorter-term obligations.  Debt obligations acquired at a discount are subject
to greater fluctuations of market value in response to changing interest rates
than debt obligations of comparable maturities which are not subject to such
discount.

     Investments in emerging country government debt securities involve special
risks.  Certain emerging countries have historically experienced, and may
continue to experience, high rates of inflation, high interest rates, exchange
rate fluctuations, large amounts of external debt, balance of payments and trade
difficulties and extreme poverty and unemployment. The issuer or governmental
authority that controls the repayment of an emerging country's debt may not be
able or willing to repay the principal and/or interest when due in accordance
with the terms of such debt.  As a result of the foregoing, a government obligor
may default on its obligations.  If such an event occurs, the Portfolio may have
limited legal recourse against the issuer and/or guarantor.  Remedies must, in
some cases, be pursued in the courts of the defaulting party itself, and the
ability of the holder of foreign government debt securities to obtain recourse
may be subject to the political climate in the relevant country.   In addition,
no assurance can be given that the holders of commercial bank debt will not
contest payments to the holders of other foreign government debt obligations in
the event of default under their commercial bank loan agreements.

BRADY BONDS.  The Emerging Markets Debt Portfolio may invest in certain debt
obligations customarily referred to as "Brady Bonds," which are created through
the exchange of existing commercial bank loans to foreign entities for new
obligations in connection with debt restructuring under a plan introduced by
former U.S. Secretary of the Treasury Nicholas F. Brady (the "Brady Plan").
Brady Bonds have been issued only recently, and, accordingly, do not have a long
payment history.  They may be collateralized or uncollateralized and issued in
various currencies (although most are U.S. dollar-denominated) and they are
actively traded in the over-


                                        2
<PAGE>

the-counter secondary market.  The Portfolio may purchase Brady Bonds either in
the primary or secondary markets.  The price and yield of Brady Bonds purchased
in the secondary market will reflect the market conditions at the time of
purchase, regardless of the stated face amount and the stated interest rate.
With respect to Brady Bonds with no or limited collateralization, the Portfolio
will rely for payment of interest and principal primarily on the willingness and
ability of the issuing government to make payment in accordance with the terms
of the bonds.

     U.S. dollar-denominated, collateralized Brady Bonds, which may be fixed
rate par bonds or floating rate discount bonds, are generally collateralized in
full as to principal due at maturity by U.S. Treasury zero coupon obligations
which have the same maturity as the Brady Bonds.  Interest payments on these
Brady Bonds generally are collateralized by cash or securities in an amount
that, in the case of fixed rate bonds, is equal to at least one year of rolling
interest payments or, in the case of floating rate bonds, initially is equal to
at least one year's rolling interest payments based on the applicable interest
rate at that time and is adjusted at regular intervals thereafter.  Certain
Brady Bonds are entitled to "value recovery payments" in certain circumstances,
which in effect constitute supplemental interest payments but generally are not
collateralized.  Brady Bonds are often viewed as having three or four valuation
components: (i) the collateralized repayment of principal at final maturity;
(ii) the collateralized interest payments; (iii) the uncollateralized interest
payments; and (iv) any uncollateralized repayment of principal at maturity
(these uncollateralized amounts constitute the "residual risk").  In the event
of a default with respect to collateralized Brady Bonds as a result of which the
payment obligations of the issuer are accelerated, the U.S. Treasury zero coupon
obligations held as collateral for the payment of principal will not be
distributed to investors, nor will such obligations be sold and the proceeds
distributed.  The collateral will be held to the scheduled maturity of the
defaulted Brady Bonds by the collateral agent, at which time the face amount of
the collateral will equal the principal payments which would have then been due
on the Brady Bonds in the normal course.  In addition, in light of the residual
risk of the Brady Bonds and, among other factors, the history of defaults with
respect to commercial bank loans by public and private entities of countries
issuing Brady Bonds, investments in Brady Bonds should be viewed as speculative.

     Brady Plan debt restructuring totalling approximately $73 billion have been
implemented to date in Argentina, Bulgaria, Costa Rica, Ecuador, Mexico,
Nigeria, the Philippines, Uruguay and Venezuela, with the largest proportion of
Brady Bonds having been issued to date by Mexico and Venezuela.  Brazil and
Poland have announced plans to issue Brady Bonds aggregating approximately $52
billion, based on current estimates.  There can be no assurance that the
circumstances regarding the issuance of Brady Bonds by these countries will not
change.

STRUCTURED SECURITIES.  The Emerging Markets Debt Portfolio may also invest a
portion of its assets in interests in entities organized and operated solely for
the purpose of restructuring the investment characteristics of sovereign debt
obligations.  This type of restructuring involves the deposit with or purchase
by an entity, such as a corporation or trust, of specified instruments (such as
commercial bank loans or Brady Bonds) and the issuance by that entity of one or
more classes of securities ("Structured Securities") backed by, or representing
interests in, the underlying instruments.  The cash flow on the underlying
instruments may be apportioned among the newly issued Structured Securities to
create securities with different investment characteristics such as varying
maturities, payment priorities and interest rate provisions, and the extent of
the payments made with respect to Structured Securities is dependent on the
extent of the cash flow on the underlying instruments.  Because Structured
Securities of the type in which the Portfolio anticipates it will invest
typically involve no credit enhancement, their credit risk generally will be
equivalent to that of the underlying instruments.  The Portfolio is permitted to
invest in a class of Structured Securities that is either subordinated or
unsubordinated to the right of payment of another class.  Subordinated
Structured Securities typically have higher yields and present greater risks
than unsubordinated Structured Securities.  Certain issuers of Structured
Securities may be deemed to be "investment companies" as defined in the 1940
Act.   As a result, the Portfolio's investment in these Structured Securities
may be limited by restrictions contained in the 1940 Act.  Structured Securities
are typically sold in private placement transactions, and there currently is no
active trading market for Structured Securities.

LOAN PARTICIPATIONS AND ASSIGNMENTS.  The Emerging Markets Debt Portfolio may
also invest in fixed and floating rate loans ("Loans") arranged through private
negotiations between an issuer of sovereign debt obligations and one or more
financial institutions ("Lenders").  The Portfolio's investments in Loans are
expected in most instances to be in the form of participations in Loans
("Participations") and assignments of all or a portion of Loans ("Assignments")
from third parties.  The Portfolio's investment in Participations typically will
result in the Portfolio having a contractual relationship only with the Lender
and not with the borrower.  The Portfolio will have the right to receive
payments of principal, interest and any fees to which it is entitled only from
the Lender selling the Participation and only upon receipt by the Lender of the
payments from the borrower.  In connection with purchasing Participations, the
Portfolio generally will have no right to enforce compliance by the borrower
with the terms of the loan agreement relating to the Loan, nor any rights of
set-off against the borrower, and the Portfolio may not directly benefit from
any collateral supporting the Loan in which it has purchased the Participation.
As a result, the Portfolio may be subject to the credit risk of both the
borrower and the Lender that is selling the Participation.  In the event of the
insolvency of the Lender selling a Participation, the Portfolio may be treated
as a general creditor of the Lender and may not benefit from any set-off between
the Lender and the


                                        3
<PAGE>

borrower. Certain Participations may be structured in a manner designed to avoid
purchasers of Participations being subject to the credit risk of the Lender with
respect to the Participation, but even under such a structure, in the event of
the Lender's insolvency, the Lender's servicing of the Participation may be
delayed and the assignability of the Participation impaired.  The Portfolio will
acquire Participations only if the Lender interpositioned between the Portfolio
and the borrower is determined by the Adviser to be creditworthy.

     When the Portfolio purchases Assignments from Lenders it will acquire
direct rights against the borrower on the Loan. Because Assignments are arranged
through private negotiations between potential assignees and potential
assignors, however, the rights and obligations acquired by the Portfolio as the
purchaser of an Assignment may differ from, and be more limited than, those held
by the assigning Lender.  The assignability of certain sovereign debt
obligations is restricted by the governing documentation as to the nature of the
assignee such that the only way in which the Portfolio may acquire an interest
in a loan is through a Participation and not an Assignment.  The Portfolio may
have difficulty disposing of Assignments and Participations because to do so it
will have to assign such securities to a third party.  Because there is no
liquid market for such securities, the Portfolio anticipates that such
securities could be sold only to a limited number of institutional investors.
The lack of a liquid secondary market may have an adverse impact on the value of
such securities and the Portfolio's ability to dispose of particular Assignments
or Participations when necessary to meet the Portfolio's liquidity needs or in
response to a specific economic event such as a deterioration in the
creditworthiness of the borrower.  The lack of a liquid secondary market for
Assignments and Participations also may make it more difficult for the Portfolio
to assign a value to these securities for purposes of valuing the Portfolio's
securities and calculating its net asset value.

FORWARD FOREIGN CURRENCY EXCHANGE CONTRACTS

     The U.S. dollar value of the assets of the Global Equity, International
Equity, International Small Cap, Asian Equity, European Equity, Japanese Equity,
Latin American, International Magnum, Global Fixed Income, Active Country
Allocation, China Growth, Emerging Markets, Emerging Markets Debt and Gold
Portfolios and, to the extent they invest in securities denominated in foreign
currencies, the assets of the Emerging Growth, MicroCap, Aggressive Equity,
Small Cap Value Equity, Value Equity, Balanced, Fixed Income and High Yield
Portfolios may be affected favorably or unfavorably by changes in foreign
currency exchange rates and exchange control regulations, and the Portfolios may
incur costs in connection with conversions between various currencies.  The
Portfolios will conduct their foreign currency exchange transactions either on a
spot (i.e., cash) basis at the spot rate prevailing in the foreign currency
exchange market, or through entering into forward contracts to purchase or sell
foreign currencies.  A forward currency exchange contract involves an obligation
to purchase or sell a specific currency at a future date, which may be any fixed
number of days from the date of the contract agreed upon by the parties, at a
price set at the time of the contract.  These contracts are traded in the
interbank market conducted directly between currency traders (usually large
commercial banks) and their customers.  A forward contract generally has no
deposit requirement, and no commissions are charged at any stage for such
trades.  The Gold Portfolio may also enter into precious metals forward
contracts.  See "Precious Metals Forward and Futures Contracts and Options"
below.

     The Portfolios may enter into forward foreign currency exchange contracts
in several circumstances.  When a Portfolio enters into a contract for the
purchase or sale of a security denominated in a foreign currency, or when a
Portfolio anticipates the receipt in a foreign currency of dividends or interest
payments on a security which it holds, the Portfolio may desire to "lock-in" the
U.S. dollar price of the security or the U.S. dollar equivalent of such dividend
or interest payment, as the case may be.  By entering into a forward contract
for a fixed amount of dollars, for the purchase or sale of the amount of foreign
currency involved in the underlying transactions, the Portfolio will be able to
protect itself against a possible loss resulting from an adverse change in the
relationship between the U.S. dollar and the subject foreign currency during the
period between the date on which the security is purchased or sold, or on which
the dividend or interest payment is declared, and the date on which such
payments are made or received.

   
     Additionally, when any of these Portfolios anticipates that the currency of
a particular foreign country may suffer a substantial decline against the U.S.
dollar, it may enter into a forward contract for a fixed amount of dollars, to
sell the amount of foreign currency approximating the value of some or all of
such Portfolio's securities denominated in such foreign currency.  The precise
matching of the forward contract amounts and the value of the securities
involved will not generally be possible since the future value of securities in
foreign currencies will change as a consequence of market movements in the value
of these securities between the date on which the forward contract is entered
into and the date it matures.  The projection of short-term currency market
movement is extremely difficult, and the successful execution of a short-term
hedging strategy is highly uncertain. None of the Portfolios intend to enter
into such forward contracts to protect the value of portfolio securities on a
continuous basis.  The Portfolios will not enter into such forward contracts or
maintain a net exposure to such contracts where the consummation of the
contracts would obligate such Portfolio to deliver an amount of foreign
currency in excess of the value of such Portfolio's securities or other assets
denominated in that currency.
    

     Under normal circumstances, consideration of the prospect for currency
parities will be incorporated into the long-term investment decisions made with
regard to overall diversification strategies.  However, the management of the
Fund believes that it


                                        4
<PAGE>

is important to have the flexibility to enter into such forward contracts when
it determines that the best interests of the performance of each Portfolio will
thereby be served.  Except under circumstances where a segregated account is not
required under the 1940 Act or the rules adopted thereunder, the Fund's
Custodian will place cash, U.S. government securities, or high-grade debt
securities into a segregated account of a Portfolio in an amount equal to the
value of such Portfolio's total assets committed to the consummation of forward
currency exchange contracts.  If the value of the securities placed in the
segregated account declines, additional cash or securities will be placed in the
account on a daily basis so that the value of the account will be equal to the
amount of such Portfolio's commitments with respect to such contracts.

     The Portfolios generally will not enter into a forward contract with a term
of greater than one year.  At the maturity of a forward contract, a Portfolio
may either sell the portfolio security and make delivery of the foreign
currency, or it may retain the security and terminate its contractual obligation
to deliver the foreign currency by purchasing an "offsetting" contract with the
same currency trader obligating it to purchase, on the same maturity date, the
same amount of the foreign currency.

     It is impossible to forecast with absolute precision the market value of a
particular portfolio security at the expiration of the contract.  Accordingly,
it may be necessary for a Portfolio to purchase additional foreign currency on
the spot market (and bear the expense of such purchase) if the market value of
the security is less than the amount of foreign currency that such Portfolio is
obligated to deliver and if a decision is made to sell the security and make
delivery of the foreign currency.

     If a Portfolio retains the portfolio security and engages in an offsetting
transaction, such Portfolio will incur a gain or a loss (as described below) to
the extent that there has been movement in forward contract prices.  Should
forward prices decline during the period between a Portfolio entering into a
forward contract for the sale of a foreign currency and the date it enters into
an offsetting contract for the purchase of the foreign currency, such Portfolio
will realize a gain to the extent that the price of the currency it has agreed
to sell exceeds the price of the currency it has agreed to purchase.  Should
forward prices increase, such Portfolio would suffer a loss to the extent that
the price of the currency it has agreed to purchase exceeds the price of the
currency it has agreed to sell.

     The Portfolios are not required to enter into such transactions with regard
to their foreign currency-denominated securities.  It also should be realized
that this method of protecting the value of portfolio securities against a
decline in the value of a currency does not eliminate fluctuations in the
underlying prices of the securities.  It simply establishes a rate of exchange
which one can achieve at some future point in time.  Additionally, although such
contracts tend to minimize the risk of loss due to a decline in the value of the
hedged currency, at the same time, they tend to limit any potential gain which
might result should the value of such currency increase.

FUTURES CONTRACTS

   
     The Equity Growth, Aggressive Equity, Value Equity, Balanced, Small Cap
Value Equity, Active Country Allocation, Gold, Latin American, U.S. Real Estate,
Emerging Markets, Emerging Markets Debt, International Magnum and China Growth
Portfolios may enter into futures contracts and options on futures contracts for
the purpose of remaining fully invested and reducing transactions costs.  The
Fixed Income, Municipal Bond, Mortgage-Backed Securities, High Yield, Money
Market, Municipal Money Market, Active Country Allocation, Equity Growth,
Aggressive Equity, Gold, Latin American, U.S. Real Estate, Emerging Markets,
Emerging Markets Debt, International Magnum and China Growth Portfolios may also
enter into futures contracts for hedging purposes.  No Portfolio will enter into
futures contracts or options thereon for speculative purposes.  The Gold
Portfolio may also enter into futures contracts and options thereon on precious
metals.  See "Precious Metals Forward and Futures Contracts and Options" below.
The China Growth and Latin American Portfolios may also enter into futures and
options thereon on stock and other securities indices and currencies.  Futures
contracts provide for the future sale by one party and purchase by another party
of a specified amount of a specific security at a specified future time and at a
specified price.  Futures contracts, which are standardized as to maturity date
and underlying financial instrument, are traded on national futures exchanges.
Futures exchanges and trading are regulated under the Commodity Exchange Act by
the Commodity Futures Trading Commission ("CFTC"), a U.S. government agency.
    

     Although futures contracts by their terms call for actual delivery or
acceptance of the underlying securities or currencies, in most cases the
contracts are closed out before the settlement date without the making or taking
of delivery.  Closing out an open futures position is done by taking an opposite
position ("buying" a contract which has previously been "sold" or "selling" a
contract previously "purchased") in an identical contract to terminate the
position.  Brokerage commissions are incurred when a futures contract is bought
or sold.

     Futures contracts on securities indices or other indices do not require the
physical delivery of securities, but merely provide for profits and losses
resulting from changes in the market value of a contract to be credited or
debited at the close of each trading


                                        5
<PAGE>

day to the respective accounts of the parties to the contract.  On the
contract's expiration date a final cash settlement occurs and the futures
position is simply closed out.  Changes in the market value of a particular
futures contract reflect changes in the level of the index on which the futures
contract is based.

     Futures traders are required to make a good faith margin deposit in cash or
government securities with a broker or custodian to initiate and maintain open
positions in futures contracts.  A margin deposit is intended to assure
completion of the contract (delivery or acceptance of the underlying security)
if it is not terminated prior to the specified delivery date.  Minimal initial
margin requirements are established by the futures exchange and may be changed.
Brokers may establish deposit requirements which are higher than the exchange
minimums.  Futures contracts are customarily purchased and sold for prices that
may range upward from less than 5% of the value of the contract being traded.

     After a futures contract position is opened, the value of the contract is
marked to market daily.  If the futures contract price changes to the extent
that the margin on deposit does not satisfy margin requirements, payment of an
additional "variation" margin will be required.  Conversely, a change in the
contract value may reduce the required margin, resulting in a repayment of
excess margin to the contract holder.  Variation margin payments are made to and
from the futures broker for as long as the contract remains open.  The
Portfolios expect to earn interest income on their margin deposits.  With
respect to each long position in a futures contract or option thereon, the
underlying commodity value of such contract will always be covered by cash and
cash equivalents set aside plus accrued profits held at the futures commission
merchant.

     The Portfolios may purchase and write call and put options on futures
contracts which are traded on a U.S. Exchange (and in the case of the China
Growth and Latin American Portfolios, on any recognized securities or futures
exchange to the extent permitted by the CFTC) and enter into closing
transactions with respect to such options to terminate an existing position.  An
option on a futures contract gives the purchaser the right (in return for the
premium paid) to assume a position in a futures contract (a long position if the
option is a call and a short position if the option is a put) at a specified
exercise price at any time during the term of the option.  Upon exercise of the
option, the delivery of the accumulated balance in the writer's futures margin
account, which represents the amount by which the market price of the futures
contract at the time of exercise exceeds, in the case of a call, or is less
than, in the case of a put, the exercise price of the option on the futures
contract.

     The Portfolios will purchase and write options on futures contracts for
identical purposes to those set forth above for the purchase of a futures
contract (purchase of a call option or sale of a put option) and the sale of a
futures contract (purchase of a put option or sale of a call option), or to
close out a long or short position in futures contracts.

     Traders in futures contracts may be broadly classified as either "hedgers"
or "speculators."  Hedgers use the futures markets primarily to offset
unfavorable changes in the value of securities otherwise held for investment
purposes or expected to be acquired by them.  Speculators are less inclined to
own the underlying securities with futures contracts which they trade, and use
futures contracts with the expectation of realizing profits from market
fluctuations.  The Portfolios intend to use futures contracts only for hedging
purposes.

     Regulations of the CFTC applicable to the Portfolios require that all
futures transactions constitute bona fide hedging transactions except that a
Portfolio may engage in futures transactions that do not constitute bona fide
hedging to the extent that not more than 5% of the liquidation value of a
Portfolio's total assets are required as margin deposits or premiums for such
transactions.  The Portfolios will only sell futures contracts to protect
securities owned against declines in price or purchase contracts to protect
against an increase in the price of securities intended for purchase.  As
evidence of this hedging interest, the Portfolios expect that approximately 75%
of their futures contracts will be "completed"; that is, equivalent amounts of
related securities will have been purchased or are being purchased by the
Portfolios upon sale of open futures contracts.

     Although techniques other than the sale and purchase of futures contracts
could be used to control the Portfolios' exposure to market fluctuations, the
use of futures contracts may be a more effective means of hedging this exposure.
While the Portfolios will incur commission expenses in both opening and closing
out futures positions, these costs are lower than transaction costs incurred in
the purchase and sale of the underlying securities.

   
RESTRICTIONS ON THE USE OF FUTURES CONTRACTS.  None of the Portfolios will enter
into futures contract transactions to the extent that, immediately thereafter,
the sum of its initial margin deposits on open contracts exceeds 5% of the
market value of its total assets.  In addition, none of the Portfolios will
enter into futures contracts to the extent that its outstanding obligations to
purchase securities under futures contracts and options on futures contracts
(and in the case of the Active Country Allocation, Equity Growth, Gold, Latin
American and China Growth Portfolios, under options, futures contracts and
options on futures contracts) would exceed 20% of its respective total assets.
    


                                        6
<PAGE>

RISK FACTORS IN FUTURES TRANSACTIONS.  Positions in futures contracts may be
closed out only on an exchange which provides a secondary market for such
futures.  However, there can be no assurance that a liquid secondary market will
exist for any particular futures contracts at any specific time.  Thus, it may
not be possible to close a futures position.  In the event of adverse price
movements, the Portfolios would continue to be required to make daily cash
payments to maintain their required margin.  In such situations, if a Portfolio
has insufficient cash, it may have to sell portfolio securities to meet its
daily margin requirement at a time when it may be disadvantageous to do so.  In
addition, a Portfolio may be required to make delivery of the instruments
underlying futures contracts it holds.  The inability to close options and
futures positions also could have an adverse impact on the Portfolio's ability
to effectively hedge.

     The Portfolios will minimize the risk that they will be unable to close out
a futures contract by only entering into futures which are traded on national
futures exchanges and for which there appears to be a liquid secondary market.

     The risk of loss in trading futures contracts in some strategies can be
substantial, due both to the low margin deposits required, and the extremely
high degree of leverage involved in futures pricing.  As a result, a relatively
small price movement in a futures contract may result in immediate and
substantial loss (as well as gain) to the investor.  For example, if, at the
time of purchase, 10% of the value of the futures contract is deposited as
margin, a subsequent 10% decrease in the value of the futures contract would
result in a total loss of the margin deposit, before any deduction for the
transaction costs, if the account were then closed out.  A 15% decrease would
result in a loss equal to 150% of the original margin deposit if the contract
were closed out.  Thus, a purchase or sale of a futures contract may result in
losses in excess of the amount invested in the contract. However, because the
Portfolios engage in futures strategies only for hedging purposes, the Adviser
does not believe that the Portfolios are subject to the risks of loss frequently
associated with futures transactions.  A Portfolio would presumably have
sustained comparable losses if, instead of the futures contract, it had invested
in the underlying security or currency and sold it after the decline.

     Utilization of futures transactions by the Portfolios does involve the risk
of imperfect or no correlation where the securities underlying futures contracts
have different maturities than the portfolio securities or currencies being
hedged.  It is also possible that a Portfolio could both lose money on futures
contracts and also experience a decline in value of its portfolio securities.
There is also the risk of loss by a Portfolio of margin deposits in the event of
bankruptcy of a broker with whom the Portfolio has an open position in a futures
contract or related option.

     Most futures exchanges limit the amount of fluctuation permitted in futures
contract prices during a single trading day.  The daily limit establishes the
maximum amount that the price of a futures contract may vary either up or down
from the previous day's settlement price at the end of a trading session.  Once
the daily limit has been reached in a particular type of contract, no trades may
be made on that day at a price beyond that limit.  The daily limit governs only
price movement during a particular trading day and therefore does not limit
potential losses, because the limit may prevent the liquidation of unfavorable
positions.  Futures contract prices have occasionally moved to the daily limit
for several consecutive trading days with little or no trading, thereby
preventing prompt liquidation of futures positions and subjecting some futures
traders to substantial losses.

MORGAN STANLEY CAPITAL INTERNATIONAL EAFE INDEX

   
     The investment objective of the Active Country Allocation Portfolio and the
International Magnum Portfolio is to provide long-term capital appreciation.
The Active Country Allocation Portfolio seeks to achieve its objective by
investing in equity securities of non-U.S. issuers which, in the aggregate,
replicate broad country indices, in accordance with country weightings
determined by the Adviser.  The Adviser utilizes a top-down approach in
selecting investments for the Active Country Allocation Portfolio that
emphasizes country selection and weighting rather than individual stock
selection.  The Active Country Allocation Portfolio invests, INTER ALIA, in
industrialized countries throughout the world that comprise the Morgan Stanley
Capital International EAFE (Europe, Australia and the Far East) Index (the "EAFE
Index").  The International Magnum Portfolio seeks to achieve its objective by
investing primarily in equity securities of non-U.S. issuers in accordance with
the EAFE country (defined below) weightings determined by the Adviser.  After
establishing regional allocation strategies, the Adviser then selects equity
securities among issuers of a region.  The International Magnum Portfolio 
invests in countries comprising the EAFE Index (each an "EAFE country").
    

     The EAFE Index is one of seven International Indices, twenty National
Indices and thirty-eight International Industry Indices making up the Morgan
Stanley Capital International Indices.   The Morgan Stanley Capital
International EAFE Index is based on the share prices of 1,066 companies listed
on the stock exchanges of Europe, Australia, New Zealand and the Far East.
"Europe" includes Austria, Belgium, Denmark, Finland, France, Germany, Italy,
The Netherlands, Norway, Spain, Sweden, Switzerland and the United Kingdom.
"Far East" includes Japan, Hong Kong and Singapore/Malaysia.


                                        7
<PAGE>

OPTIONS TRANSACTIONS

   
GENERAL INFORMATION.  As stated in the applicable Prospectus, the Active Country
Allocation, Emerging Markets, Emerging Markets Debt, Equity Growth, Aggressive
Equity, Gold, Small Cap Value Equity, Value Equity, Balanced, Latin American,
U.S. Real Estate, International Magnum and China Growth Portfolios may purchase
and sell options on portfolio securities and the China Growth and Latin American
Portfolios also may purchase and sell options on securities indices.  Additional
information with respect to option transactions is set forth below.  Call and
put options on equity securities are listed on various U.S. and foreign
securities exchanges ("listed options") and are written in over-the-counter
transactions ("OTC Options").
    

   
     Listed options are issued or guaranteed by the exchange on which they trade
or by a clearing corporation, such as Options Clearing Corporation ("OCC") in
the United States.  Ownership of a listed call option gives the fund the right
to buy from the clearing corporation or exchange, the underlying security
covered by the option at the state exercise price (the price per unit of the
underlying security or currency) by filing an exercise notice prior to the
expiration date of the option.  The writer (seller) of the option would then
have the obligation to sell to the clearing corporation or exchange, the
underlying security or currency at that exercise price prior to the expiration
date of the option, regardless of the current market price.  Ownership of
listed put option would give the Portfolio the right to sell the underlying
security or currency to the clearing corporation or exchange at the state
exercise price.  Upon notice of exercise of the put option, the writer of the
option would have the obligation to purchase the underlying security from the
clearing corporation or exchange at the exercise price.
    

   
     OTC options are purchased from or sold (written) to dealers of financial
institutions which have entered into direct agreements with the Portfolio.  With
OTC options, such variables as expiration date, exercise price and premium will
be agreed upon between the Portfolio and the transactions dealer, without the
intermediation of a third party such as a clearing corporation or exchange.  If
the transacting dealer fails to make or take delivery of the securities
underlying an option it has written, in accordance with the terms of that
option, the Portfolio would lose the premium paid for the option as well as any
anticipated benefit of the transaction.
    

   
COVERED CALL WRITING.  Each of the Portfolios may write (i.e., sell) covered
call options on portfolio securities.  By doing so, the Portfolio would become
obligated during the terms of the option to deliver the securities underlying
the option should the option holder choose to exercise the option before the
option's termination date.  In return for the call it has written, the Portfolio
will receive from the purchaser (or option holder) a premium which is the price
of the option, less a commission charged by a broker.  The Portfolio will keep
the premium regardless of whether the option is exercised.  A call option is
"covered" if the Portfolio owns the security underlying the option it has
written or has an absolute or immediate right to acquire the security by holding
a call option on such security, or maintains a sufficient amount of cash, cash
equivalents or liquid securities to purchase the underlying security.  When the
Portfolio writes covered call options, it augments its income by the premiums
received and is thereby hedged to the extent of that amount against a decline in
the price of the underlying securities and the premiums received will offset a
portion of the potential loss incurred by the Portfolio if the securities
underlying the options are ultimately sold by the Portfolio at a loss.  However,
during the option period, the Portfolio has, in return for the premium on the
option, given up the opportunity for capital appreciation above the exercise
price should the market price of the underlying security increase, but has
retained the risk of loss should the price of the underlying security decline.
The size of premiums will fluctuate with varying market conditions.
    

COVERED PUT WRITING.  Each of the Portfolios may write covered put options on
portfolio securities.  By doing so, the Portfolio incurs an obligation to buy
the security underlying the option from the purchaser of the put at the option's
exercise price at any time during the option period, at the purchaser's election
(certain listed and OTC options written by the Portfolio will be exercisable by
the purchaser only on a specific date).  Generally, a put option is "covered" if
the Portfolio maintains cash, U.S. Government securities or other high grade
debt obligations equal to the exercise price of the option or if the Portfolio
holds a put option on the same underlying security with a similar or higher
exercise price.

   
     Each of the Portfolios will write put options to receive the premiums paid
by purchasers; when the Adviser (and also the Sub-Adviser with respect to the
Gold Portfolio) wishes to purchase the security underlying the option at a price
lower than its current market price, in which case it will write the covered put
at an exercise price reflecting the lower purchase price sought; and to close
out long put option positions.
    

PURCHASE OF PUT AND CALL OPTIONS.  Each of the Portfolios may purchase listed or
OTC put or call options on its portfolio securities in amounts exceeding no more
than 5% of its total assets.  When the Portfolio purchases a call option it
acquires the right to purchase a designated security at a designated price (the
"exercise price"), and when the Portfolio purchases a put option it acquires the
right to sell a designated security at the exercise price, in each case on
or before a specified date (the "termination date"), usually not more than nine
months from the date the option is issued.


                                        8
<PAGE>

     The Portfolio may purchase call options to close out a covered call
position or to protect against an increase in the price of a security it
anticipates purchasing.  The Portfolio may purchase put options on securities
which it holds in its portfolio only to protect itself against a decline in the
value of the security.  If the value of the underlying security were to fall
below the exercise price of the put purchased in an amount greater than the
premium paid for the option, the Portfolio would incur no additional loss.  The
Portfolio may also purchase put options to close out written put positions in a
manner similar to call option closing purchase transactions.

     The amount the Portfolio pays to purchase an option is called a "premium",
and the risk assumed by the Portfolio when it purchases an option is the loss of
this premium.  Because the price of an option tends to move with that of its
underlying security, if the Portfolio is to make a profit, the price of the
underlying security must change and the change must be sufficient to cover the
premium and commissions paid.  A price change in the security underlying the
option does not assure a profit since prices in the options market may not
always reflect such a change.

   
OPTIONS ON SECURITIES INDICES.   The China Growth and Latin American Portfolios
may purchase and write put and call options on securities indices and enter into
related closing transactions in order to hedge against the risk of market
price fluctuations or to increase income to the Portfolio.
    

     Call and put options on indices are similar to options on securities except
that, rather than the right to purchase or sell particular securities at a
specified price, options on an index give the holder the right to receive, upon
exercise of the option, an amount of cash if the closing level of the underlying
index is greater than (or less than, in the case of puts) the exercise price of
the option.  This amount of cash is equal to the difference between the closing
price of the index and the exercise price of the option, expressed in dollars
multiplied by a specified number.  Thus, unlike options on individual
securities, all settlements are in cash, and gain or loss depends on price
movements in the particular market represented by the index generally (or in a
particular industry or segment of the market) rather than the price movements in
individual securities.

     All options written on indices must be covered.  When the Portfolio writes
an option on an index, it will establish a segregated account containing cash,
U.S. government securities or other high quality liquid debt securities with its
custodian in an amount at least equal to the market value of the option and will
maintain the account while the option is open or will otherwise cover the
transaction.

     The Portfolio may choose to terminate an option position by entering into a
closing transaction.  The ability of the Portfolio to enter into closing
transactions depends upon the existence of a liquid secondary market for such
transactions.

OPTIONS ON CURRENCIES.  The China Growth and Latin American Portfolios may
purchase and write put and call options on foreign currencies (traded on U.S.
and foreign exchanges or over-the-counter markets) to manage the Portfolio's
exposure to changes in dollar exchange rates.  Call options on foreign currency
written by the Portfolio will be "covered," which means that the Portfolio will
own an equal amount of the underlying foreign currency.  With respect to put
options on foreign currency written by the Portfolio, the Portfolio will
establish a segregated account with the Fund's Custodian consisting of cash,
U.S. government securities or other high quality liquid debt securities in an
amount equal to the amount the Portfolio would be required to pay upon exercise
of the put.

PORTFOLIO TURNOVER

     The portfolio turnover rate for a year is the lesser of the value of the
purchases or sales for the year divided by the average monthly market value of
the Portfolio for the year, excluding U.S. Government securities and securities
with maturities of one year or less.  The portfolio turnover rate for a year is
calculated by dividing the lesser of sales or the average monthly value of the
Portfolio's portfolio purchases of portfolio securities during that year by
securities, excluding money market instruments.  The rate of portfolio turnover
will not be a limiting factor when the Portfolio deems it appropriate to
purchase or sell securities for the Portfolio.  However, the U.S. federal tax
requirement that the Portfolio derive less than 30% of its gross income from the
sale or disposition of securities held less than three months may limit the
Portfolio's ability to dispose of its securities.  See "Taxes."

PRECIOUS METALS FORWARD AND FUTURES CONTRACTS AND OPTIONS ON FUTURES CONTRACTS

     The Gold Portfolio may enter into futures contacts on precious ("precious
metals futures") metals as a hedge against changes in the prices of precious
metals held or intended to be acquired by the Portfolio, but not for speculation
or for achieving leverage.  The Portfolio's hedging activities may include
purchases of futures contracts as an offset against the effect of anticipated
increases in the price of a precious metal which the Portfolio intends to
acquire ("anticipatory hedge") or sales of futures contracts as an offset
against the effect of anticipated declines in the price of precious metal which
the Portfolio owns ("hedge against an existing position").


                                        9
<PAGE>

     The Portfolio will enter into precious metals forward contracts which are
similar to precious metals futures contracts, in that they provide for the
purchase or sale of precious metals at an agreed price with delivery to take
place at an agreed future time.  However, unlike futures contracts, forward
contracts are negotiated contracts which are primarily used in the dealer
market.  Unlike the futures contract market, which is regulated by the CFTC and
by the regulations of the commodity exchanges, the forward contract market is
unregulated.  The Portfolio will use forward contracts for the same hedging
purposes as those applicable to futures contracts, as described above.  When the
Portfolio enters into a forward contract it will establish with the custodian a
segregated account consisting of cash, cash equivalents or bullion equal to the
market value of the forward contract purchased.

     Precious metals futures and forward contract prices can be volatile and are
influenced principally by changes in spot market prices, which in turn are
affected by a variety of political and economic factors.  In addition,
expectations of changing market conditions may at times influence the prices of
such futures and forward contracts, and changes in the cost of holding physical
precious metals, including storage, insurance and interest expense, will also
affect the relationship between spot and futures or forward prices.  While the
correlation between changes in prices of futures and forward contracts and
prices of the precious metals being hedged by such contracts has historically
been very strong, the correlation may at times be imperfect and even a well
conceived hedge may be unsuccessful to some degree because of market behavior or
unexpected precious metals price trends.  To the extent that interest rates move
in a direction opposite to that anticipated, the Portfolio may realize a loss on
a futures transaction not offset by an increase in the value of portfolio
securities.  Moreover there is a possibility of a lack of a liquid secondary
market for closing out a futures position or futures option.  The success of any
hedging technique depends upon the Adviser's and Sub-Adviser's accuracy in
predicting the direction of a market.  If these predictions are incorrect, the
Portfolio may realize a loss.

   
     The Portfolio may also purchase (buy) and write (sell) covered call or put
options on precious metals futures contracts.  Such options would be purchased
solely for hedging purposes similar to those applicable to the purchase and sale
of futures contracts.  Call options might be purchased to hedge against an
increase in the price of precious metals the Portfolio intends to acquire, and
put options may be purchased to hedge against a decline in the price of precious
metals owned by the Portfolio.  As is the case with futures contracts, options
on precious metals futures may facilitate the Portfolio's acquisition of
precious metals or permit the Portfolio to defer disposition of precious metals
for tax or other purposes.  The Portfolio may not purchase options on precious
metals and precious metals futures contracts if the premiums paid for all such
options, together with margin deposits on precious metals future contracts,
would exceed 5% of the Portfolio's total assets at the time the option is
purchased.
    

   
     One of the risks which may arise in employing futures contracts to protect
against the price volatility of the Portfolio's assets is that the price of
precious metals subject to futures contracts (and thereby the futures contracts
prices) may correlate imperfectly with the prices of such assets.  A correlation
may also be distorted by the fact that the futures market is dominated by short-
term traders seeking to profit from the difference between a contract or
security price objective and their cost of borrowed funds.  Such distortions are
generally minor and would diminish as the contract approached maturity.
    

SECURITIES LENDING

   
     Each Portfolio may lend its investment securities to qualified
institutional investors who need to borrow securities in order to complete
certain transactions, such as covering short sales, avoiding failures to deliver
securities or completing arbitrage operations.  By lending its investment
securities, a Portfolio attempts to increase its net investment income through
the receipt of interest on the loan.  Any gain or loss in the market price of
the securities loaned that might occur during the term of the loan would be for
the account of the Portfolio.  Each Portfolio may lend its investment securities
to qualified brokers, dealers, domestic and foreign banks or other financial
institutions, so long as the terms, structure and the aggregate amount of such
loans are not inconsistent with the Investment Company Act of 1940, as amended
(the "1940 Act"), or the Rules and Regulations or interpretations of the
Securities and Exchange Commission (the "Commission") thereunder, which
currently require that (a) the borrower pledge and maintain with the portfolio
collateral consisting of cash, an irrevocable letter of credit issued by a
domestic U.S. bank, or securities issued or guaranteed by the United States
Government having a value at all times not less than 100% of the value of the
securities loaned, (b) the borrower add to such collateral whenever the price of
the securities loaned rises (i.e., the borrower "marks to the market" on a daily
basis), (c) the loan be made subject to termination by the Portfolio at any
time, and (d) the Portfolio receive reasonable interest on the loan (which may
include the Portfolio investing any cash collateral in interest bearing
short-term investments), any distributions on the loaned securities and any
increase in their market value.  There may be risks of delay in recovery of the
securities or even loss of rights in the collateral should the borrower of the
securities fail financially.  However, loans will only be made to borrowers
deemed by the Advisor to be of good standing and when, in the judgment of the
Advisor, the consideration which can be earned currently from such securities
loans justifies the attendant risk. All relevant facts and circumstances,
including the creditworthiness of the broker, dealer or institution, will be
considered in making decisions with respect to the lending of securities,
subject to review by the Board of Directors of the Fund.
    


                                       10
<PAGE>

     At the present time, the staff of the Commission does not object if an
investment company pays reasonable negotiated fees in connection with loaned
securities, so long as such fees are set forth in a written contract and
approved by the investment company's Board of Directors.  In addition, voting
rights may pass with the loaned securities, but if a material event will occur
affecting an investment on loan, the loan must be called and the securities
voted.

SHORT SALES

     The Emerging Markets Debt, Latin American and Aggressive Equity Portfolios
may from time to time sell securities short without limitation but consistent
with applicable legal requirements, although initially the Portfolio does not
intend to sell securities short.  A short sale is a transaction in which the
Portfolio would sell securities it owns or has the right to acquire at no added
cost (i.e., "against the box") or does not own (but has borrowed) in
anticipation of a decline in the market price of the securities.  When the
Portfolio makes a short sale of borrowed securities, the proceeds it receives
from the sale will be held on behalf of a broker until the Portfolio replaces
the borrowed securities.  To deliver the securities to the buyer, the Portfolio
will need to arrange through a broker to borrow the securities and, in so doing,
the Portfolio will become obligated to replace the securities borrowed at their
market price at the time of replacement, whatever that price may be.  The
Portfolio may have to pay a premium to borrow the securities and must pay any
dividends or interest payable on the securities until they are replaced.

     The Portfolio's obligation to replace the securities borrowed in connection
with a short sale will be secured by collateral deposited with the broker that
consists of cash, U.S. Government Securities or other liquid, high grade debt
obligations.  In addition, if the short sale is not "against the box," the
Portfolio will place in a segregated account with its custodian, or designated
sub-custodian, an amount of cash, U.S. Government Securities or other liquid
high grade debt obligations equal to the difference, if any, between (1) the
market value of the securities sold at the time they were sold short and (2) any
cash, U.S. Government Securities or other liquid high grade debt obligations
deposited as collateral with the broker in connection with the short sale (not
including the proceeds of the short sale).  Until it replaces the borrowed
securities, the Portfolio will maintain the segregated account daily at a level
so that (1) the amount deposited in the account plus the amount deposited with
the broker (not including the proceeds from the short sale) will equal the
current market value of the securities sold short and (2) the amount deposited
in the account plus the amount deposited with the broker (not including the
proceeds from the short sale) will not be less than the market value of the
securities at the time they were sold short.

     Short sales by the Portfolio involve certain risks and special
considerations.  Possible losses from short sales differ from losses that could
be incurred from a purchase of a security, because losses from short sales may
be unlimited, whereas losses from purchases can equal only the total amount
invested.

   
SPECIAL RISKS ASSOCIATED WITH FORWARD CONTRACTS, FOREIGN CURRENCY FUTURES
CONTRACTS AND OPTIONS THEREON AND OPTIONS ON FOREIGN CURRENCIES
    

     Transactions in forward contracts, as well as futures and options on
foreign currencies, are subject to the risk of governmental actions affecting
trading in or the prices of currencies underlying such contracts, which could
restrict or eliminate trading and could have a substantial adverse effect on the
value of positions held by the Portfolios permitted to engage in such hedging
transactions.  In addition, the value of such positions could be adversely
affected by a number of other complex political and economic factors applicable
to the countries issuing the underlying currencies.

     Furthermore, unlike trading in most other types of instruments, there is no
systematic reporting of last sale information with respect to the foreign
currencies underlying forward contracts, futures contracts and options.  As a
result, the available information on which a Portfolio's trading systems will be
based may not be as complete as the comparable data on which such Portfolio
makes investment and trading decisions in connection with securities and other
transactions.  Moreover, because the foreign currency market is a global,
twenty-four hour market, events could occur on that market which will not be
reflected in the forward, futures or options markets until the following day,
thereby preventing a Portfolio from responding to such events in a timely
manner.

     Settlements of over-the-counter forward contracts or of the exercise of
foreign currency options generally must occur within the country issuing the
underlying currency, which in turn requires parties to such contracts to accept
or make delivery of such currencies in conformity with any United States or
foreign restrictions and regulations regarding the maintenance of foreign
banking relationships, fees, taxes or other charges.

     Unlike currency futures contracts and exchange-traded options, options on
foreign currencies and forward contracts are not traded on contract markets
regulated by the CFTC or (with the exception of certain foreign currency
options) the Commission.  In an over-the-counter trading environment, many of
the protections associated with transactions on exchanges will not be available.


                                       11
<PAGE>

For example, there are no daily price fluctuation limits, and adverse market
movements could therefore continue to an unlimited extent over a period of time.
Although the purchaser of an option cannot lose more than the amount of the
premium plus related transaction costs, this entire amount could be lost.
Moreover, an option writer could lose amounts substantially in excess of its
initial investment due to the margin and collateral requirements associated with
such option positions.  Similarly, there is no limit on the amount of potential
losses on forward contracts to which a Portfolio is a party.

     In addition, over-the-counter transactions can only be entered into with a
financial institution willing to take the opposite side, as principal, of a
Portfolio's position unless the institution acts as broker and is able to find
another counterparty willing to enter into the transaction with such Portfolio.
Where no such counterparty is available, it will not be possible to enter into a
desired transaction.  There also may be no liquid secondary market in the
trading of over-the-counter contracts, and a Portfolio may be unable to close
out options purchased or written, or forward contracts entered into, until their
exercise, expiration or maturity.  This in turn could limit a Portfolio's
ability to realize profits or to reduce losses on open positions and could
result in greater losses.

     Furthermore, over-the-counter transactions are not backed by the guarantee
of an exchange's clearing corporation.  A Portfolio will therefore be subject to
the risk of default by, or the bankruptcy of, the financial institution serving
as its counterparty.  One or more of such institutions also may decide to
discontinue its role as market-maker in a particular currency, thereby
restricting a Portfolio's ability to enter into desired hedging transactions.  A
Portfolio will enter into over-the-counter transactions only with parties whose
creditworthiness has been reviewed and found satisfactory by the Adviser.

     Over-the-counter options on foreign currencies, like exchange-traded
commodity futures contracts and commodity option contracts, are within the
exclusive regulatory jurisdiction of the CFTC.  The CFTC currently permits the
trading of such options, but only subject to a number of conditions regarding
the commercial purpose of the purchaser of such options.  The China Growth and
Latin American Portfolios are not able to determine at this time whether or to
what extent the CFTC may impose additional restrictions on the trading of over-
the-counter options on foreign currencies at some point in the future, or the
effect that any restrictions may have on the hedging strategies to be
implemented by the Portfolio.  Forward contracts and currency swaps are not
presently subject to regulation by the CFTC, although the CFTC may in the future
assert or be granted authority to regulate such instruments.  In such event, a
Portfolio's ability to utilize forward contracts and currency swaps in the
manner set forth above and in the applicable Prospectus could be restricted.

     Options on foreign currencies traded on a national securities exchange are
within the jurisdiction of the Commission, as are other securities traded on
such exchanges.  As a result, many of the protections provided to traders on
organized exchanges will be available with respect to such transactions.  In
particular, all foreign currency options positions entered into on a national
securities exchange are cleared and guaranteed by the Options Clearing
Corporation ("OCC"), thereby reducing the risk of counterparty default.
Further, a liquid secondary market in options traded on a national securities
exchange may be more readily available than in the over-the-counter market,
potentially permitting a Portfolio to liquidate open positions at a profit prior
to exercise or expiration, or to limit losses in the event of adverse market
movements.

     The purchase and sale of exchange-traded foreign currency options, however,
is subject to the risks of the availability of a liquid secondary market
described above, as well as the risks regarding adverse market movements,
margining of options written, the nature of the foreign currency market,
possible intervention by governmental authorities and the effect of other
political and economic events.  In addition, exchange-traded options on foreign
currencies involve certain risks not presented by the over-the-counter market.
For example, exercise and settlement of such options must be made exclusively
through the OCC, which has established banking relationships in applicable
foreign countries for this purpose.  As a result, the OCC may, if it determines
that foreign governmental restrictions or taxes would prevent the orderly
settlement of foreign currency option exercises, or would result in undue
burdens on the OCC or its clearing member, impose special procedures for
exercise and settlement, such as technical changes in the mechanics of delivery
of currency, the fixing of dollar settlement prices or prohibitions on exercise.


                                      TAXES

   
     The following is only a summary of certain additional federal tax
considerations generally affecting the Fund and its shareholders that are not
described in the Prospectuses.  No attempt is made to present a detailed
explanation of the federal, state or local tax treatment of the Fund or its
shareholders, and the discussion here and in the Fund's Prospectuses is not
intended as a substitute for careful tax planning.
    

     The following discussion of federal income tax consequences is based on the
Internal Revenue Code of 1986, as amended (the "Code") and the regulations
issued thereunder as in effect on the date of this Statement of Additional
Information.  New


                                       12
<PAGE>

   
legislation, as well as administrative changes or court decisions, may
significantly change the conclusions expressed herein, and may have a
retroactive effect with respect to the transactions contemplated herein.

     Each Portfolio within the Fund is generally treated as a separate
corporation for federal income tax purposes, and thus the provisions of the Code
generally will be applied to each Portfolio separately, rather than to the Fund
as a whole.

     Each Portfolio intends to qualify and elect to be treated for each taxable
year as a regulated investment company ("RIC") under Subchapter M of the Code.
Accordingly, each Portfolio must, among other things, (a) derive at least 90% of
its gross income each taxable year from dividends, interest, payments with
respect to securities loans, gains from the sale or other disposition of stock,
securities or foreign currencies, and certain other related income, including,
generally, certain gains from options, futures and forward contracts; (b) derive
less than 30% of its gross income each taxable year from the sale or other
disposition of the following items if held less than three months (A) stock or
securities, (B) options, futures or forward contracts (other than options,
futures or forward contracts on foreign currencies), and (C) foreign currencies
(or options, futures, or forward contracts on foreign currencies) that are not
directly related to the Portfolio's principal business of investing in stocks or
securities (or options or futures with respect to stock or securities) (the
"short-short test") and (c) diversify its holdings so that, at the end of each
fiscal quarter of the Portfolio's taxable year, (i) at least 50% of the market
value of the Portfolio's total assets is represented by cash and cash items,
United States Government securities, securities of other RICs, and other
securities, with such other securities limited, in respect to any one issuer, to
an amount not greater than 5% of the value of the Portfolio's total assets or
10% of the outstanding voting securities of such issuer, and (ii) not more than
25% of the value of its total assets is invested in the securities (other than
United States Government securities or securities of other RICs) of any one
issuer or two or more issuers which the Portfolio controls and which are engaged
in the same, similar, or related trades or business.  For purposes of the 90% of
gross income requirement described above, foreign currency gains which are not
directly related to a Portfolio's principal business of investing in stock or
securities (or options or futures with respect to stock or securities) may be
excluded from income that qualifies under the 90% requirement.

     In addition to the requirements described above, in order to qualify as a
RIC, a Portfolio must distribute at least 90% of its net investment income
(which generally includes dividends, taxable interest, and the excess of net
short-term capital gains over net long-term capital losses less operating
expenses) and at least 90% of its net tax-exempt interest income, if any, to
shareholders.  If a Portfolio meets all of the RIC requirements, it will not be
subject to federal income tax on any of its net investment income or capital
gains that it distributes to shareholders.

     If a Portfolio fails to qualify as a RIC for any year, all of its income
will be subject to tax at corporate rates, and its distributions (including
capital gains distributions) will be taxable as ordinary income dividends to its
shareholders to the extent of the Portfolio's current and accumulated earnings
and profits, and will be eligible for the corporate dividends received deduction
for corporate shareholders.

     Each Portfolio will decide whether to distribute or to retain all or part
of any net capital gains (the excess of net long-term capital gains over net
short-term capital losses) in any year for reinvestment.  If any such gains are
retained, the Portfolio will pay federal income tax thereon, and, if the
Portfolio makes an election, the shareholders will include such undistributed
gains in their income, will increase their basis in Portfolio shares by 65% of
the amount included in their income and will be able to claim their share of the
tax paid by the Portfolio as a refundable credit against their federal income
tax liability.

     A gain or loss realized by a shareholder on the sale, exchange or 
redemption of shares of a Portfolio held as a capital asset will be capital 
gain or loss, and such gain or loss will be long-term if the holding period 
for the shares exceeds one year, and otherwise will be short-term.  Any loss 
realized on a sale, exchange or redemption of shares of a Portfolio will be 
disallowed to the extent the shares disposed of are replaced within the 
61-day period beginning 30 days before and ending 30 days after the shares 
are disposed of.  Any loss realized by a shareholder on the disposition of 
shares held 6 months or less is treated as a long-term capital loss to the 
extent of any distributions of net long-term capital gains received by the 
shareholder with respect to such shares or any inclusion of undistributed 
capital gain with respect to such shares.

     The conversion of Class A shares to Class B shares should not be a taxable
event to the shareholder.

     Each Portfolio will generally be subject to a nondeductible 4% federal
excise tax to the extent it fails to distribute by the end of any calendar year
at least 98% of its ordinary income for that year and 98% of its capital gain
net income (the excess of short- and long-term capital gains over short- and
long-term capital losses) for the one-year period ending on October 31 of that
year, plus certain other amounts.
    


                                       13
<PAGE>

     Each Portfolio is required by federal law to withhold 31% of reportable
payments (which may include dividends, capital gains distributions, and
redemptions) paid to shareholders who have not certified on the Account
Registration Form or on a separate form supplied by the Portfolio, that the
Social Security or Taxpayer Identification Number provided is correct and that
the shareholder is exempt from backup withholding or is not currently subject to
backup withholding.

     For certain transactions, each Portfolio is required for federal income tax
purposes to recognize as gain or loss its net unrealized gains and losses on
forward currency and futures contracts as of the end of each taxable year, as
well as those actually realized during the year.  In most cases, any such gain
or loss recognized with respect to a regulated futures contract is considered to
be 60% long-term capital gain or loss and 40% short-term capital gain or loss,
without regard to the holding period of the contract.  Realized gain or loss
attributable to a foreign currency forward contract is treated as 100% ordinary
income.  Furthermore, foreign currency futures contracts which are intended to
hedge against a change in the value of securities held by a Portfolio may affect
the holding period of such securities and, consequently, the nature of the gain
or loss on such securities upon disposition.

     As discussed above, in order for each Portfolio to continue to qualify for
federal income tax treatment as a RIC, at least 90% of its gross income for a
taxable year must be derived from certain qualifying income, including
dividends, interest, income derived from loans of securities, and gains from the
sale or other disposition of stock, securities or foreign currencies, or other
related income, including gains from options, futures and forward contracts,
derived with respect to its business of investing in stock, securities or
currencies.  Any net gain realized from the closing out of futures contracts
will therefore generally be qualifying income for purposes of the 90%
requirement.  Qualification as a RIC also requires that less than 30% of a
Portfolio's gross income be derived from the sale or other disposition of stock,
securities, options, futures or forward contracts (including certain foreign
currencies not directly related to the Fund's business of investing in stock or
securities) held less than three months.  In order to avoid realizing excessive
gains on futures contracts held less than three months, the Portfolio may be
required to defer the closing out of futures contracts beyond the time when it
would otherwise be advantageous to do so.

     Short sales engaged in by a Portfolio may reduce the holding property held
by a Portfolio which is substantially identical to the property sold short.
This rule may make it more difficult for the Portfolio to satisfy the short-
short test.  This rule may also have the effect of converting capital gains
recognized by the Portfolio from long-term to short-term as well as converting
capital losses recognized by the Portfolio from short-term to long-term.

   
     SPECIAL RULES FOR CERTAIN FOREIGN CURRENCY TRANSACTIONS.  In general, 
gains from foreign currencies and from foreign currency options, foreign 
currency futures and forward foreign exchange contracts relating to 
investments in stock, securities or foreign currencies are currently 
considered to be qualifying income for purposes of determining whether the 
Fund qualifies as a regulated investment company. It is currently unclear, 
however, who will be treated as the issuer of certain foreign currency 
instruments or how foreign currency options, futures, or forward foreign 
currency contracts will be valued for purposes of the regulated investment 
company diversification requirements applicable to the Fund. The Fund may 
request a private letter ruling from the Internal Revenue Service on some or 
all of these issues.
    
   
     Under Code Section 988, special rules are provided for certain 
transactions in a foreign currency other than the taxpayer's functional 
currency (i.e., unless certain special rules apply, currencies other than the 
U.S. dollar). In general, foreign currency gains or losses from forward 
contracts, from futures contracts that are not "regulated futures contracts", 
and from unlisted options will be treated as ordinary income or loss under 
Code Section 988. Also, certain foreign exchange gains or losses derived with 
respect to foreign fixed-income securities are also subject to Section 988 
treatment. In general, therefore, Code Section 988 gains or losses will 
increase or decrease the amount of the Fund's investment company taxable 
income available to be distributed to shareholders as ordinary income, rather 
than increasing or decreasing the amount of the Fund's net capital gain.
    
   
     If the Fund invests in an entity which is classified as a "passive 
foreign investment company" ("PFIC") for U.S. tax purposes, the application 
of certain technical tax provisions applying to such companies could result 
in the imposition of federal income tax with respect to such investments at 
the Fund level which could not be eliminated by distributions to 
shareholders. The U.S. Treasury issued proposed regulation section 1.1291-8
which establishes a mark-to-market regime which allows investment companies 
investing in PFIC's to avoid most, if not all, of the difficulties posed by 
the PFIC rules. In any event, it is not anticipated that any taxes on the 
Fund with respect to investments in PFIC's would be significant.
    
   
     A Fund's investment in options, swaps and related transactions, futures 
contracts and forward contracts, options on futures contracts and stock 
indices and certain other securities, including transactions involving actual 
or deemed short sales or foreign exchange gains or losses are subject to many 
complex and special tax rules. For example, over-the-counter options on debt 
securities and equity options, including options on stock and on narrow-based 
stock indexes, will be subject to tax under Section 1234 of the Code, 
generally producing a long-term or short-term capital gain or loss upon 
exercise, lapse or closing out of the option or sale of the underlying stock 
or security. By contrast, a Fund's treatment of certain other options, 
futures and forward contracts entered into by a Fund is generally governed by 
Section 1256 of the Code. These "Section 1256" positions generally include 
listed options on debt securities, options on broad-based stock indexes, 
options on securities indexes, options on futures contracts, regulated 
futures contracts and certain foreign currency contracts and options thereon.
    
   
     A Section 1256 position held by a Fund will generally be marked-to-market 
(i.e. treated as if it were sold for fair market value) on the last business 
day of a Fund's fiscal year, and all gain or loss associated with fiscal year 
transactions and mark-to-market positions at fiscal year end (except certain 
currency gain or loss covered by Section 988 of the Code) will generally be 
treated as 60% long-term capital gain or loss and 40% short-term capital gain 
or loss. The effect of Section 1256 mark-to-market rules may be to accelerate 
income or to convert what otherwise would have been long-term capital gains 
into short-term capital gains or short-term capital losses into long-term 
capital losses within a Fund. The acceleration of income on Section 1256 
positions may require a Fund to accrue taxable income without the 
corresponding receipt of cash. In order to generate cash to satisfy the 
distribution requirements of the Code, a Fund may be required to dispose of 
portfolio securities that they otherwise would have continued to hold or to 
use cash flows from other sources such as the sale of Fund shares. In these 
ways, any or all of these rules may affect the amount, character and timing 
of income earned and in turn distributed to shareholders by a Fund.
    
   
     When a Fund holds options or contracts which substantially diminish 
their risk of loss with respect to other positions (as might occur in some 
hedging transactions), this combination of positions could be treated as a 
"straddle" for tax purposes, resulting in possible deferral of losses, 
adjustments in the holding periods of Fund securities and conversion of 
short-term capital losses into long-term capital losses. Certain tax 
elections exist for mixed straddles i.e., straddles comprised of at least one 
Section 1256 position and at least one non-Section 1256 position which may 
reduce or eliminate the operation of these straddle rules.
    

                     SPECIAL TAX CONSIDERATIONS RELATING TO
                               MUNICIPAL BOND AND
                        MUNICIPAL MONEY MARKET PORTFOLIOS

     Each of the Municipal Bond Portfolio and the Municipal Money Market
Portfolio will qualify to pay "exempt interest dividends" to its shareholders
provided that, at the close of each quarter of its taxable year at least 50% of
the value of its total assets consists of obligations the interest on which is
exempt from federal income tax.  Current federal tax law limits the types and
volume of bonds qualifying for federal income tax exemption of interest, which
may have an effect on the ability of these Portfolios to purchase sufficient
amounts of tax-exempt securities to satisfy this requirement.  Any loss on the
sale or exchange of shares of the Municipal Bond Portfolio or the Municipal
Money Market Portfolio held for six months or less will be disallowed to the
extent of any exempt-interest dividends received by the selling shareholder with
respect to such shares.

     As noted in the Prospectus for the Municipal Bond Portfolio and the
Municipal Money Market Portfolio, exempt-interest dividends are excludable from
a shareholder's gross income for regular Federal income tax purposes.  Exempt-
interest dividends may nevertheless be subject to the alternative minimum tax
(the "Alternative Minimum Tax") imposed by Section 55 of the Code or the
environmental tax (the "Environmental Tax") imposed by Section 59A of the Code.
The Alternative Minimum Tax is imposed at the rate of up to 28% in the case of
non-corporate taxpayers and at the rate of 20% in the case of corporate
taxpayers, to the extent it exceeds the taxpayer's regular tax liability.  The
Environmental Tax is imposed at the rate of 0.12% and applies only to corporate
taxpayers.  The Alternative Minimum Tax and the Environmental Tax may be
affected by the receipt of exempt-interest dividends in two circumstances.
First, exempt-interest dividends derived from certain "private activity bonds"
issued after August 7, 1986, will generally be an item of tax preference and
therefore potentially subject to the Alternative Minimum Tax and the
Environmental Tax.  The Portfolios intend, when possible, to avoid investing in
private activity bonds.  Second, in the case of exempt-interest dividends
received by corporate shareholders, all exempt-interest dividends, regardless of
when the bonds from which they are derived were issued or whether they are
derived from private activity bonds, will be included in the corporation's
"adjusted current earnings," as defined in Section 56(g) of the Code, in
calculating the corporation's alternative minimum taxable income for purposes of
determining the Alternative Minimum Tax and the Environmental Tax.


                                       14
<PAGE>

     The percentage of income that constitutes "exempt-interest dividends" will
be determined for each year for the Municipal Bond Portfolio and the Municipal
Money Market Portfolio and will be applied uniformly to all dividends declared
with respect to the Portfolios during that year.  This percentage may differ
from the actual percentage for any particular day.

     Interest on indebtedness incurred or continued by shareholders to purchase
or carry shares of the Municipal Bond Portfolio or the Municipal Money Market
Portfolio will not be deductible for federal income tax purposes.  The deduction
otherwise allowable to property and casualty insurance companies for "losses
incurred" will be reduced by an amount equal to a portion of exempt-interest
dividends received or accrued during any taxable year.  Foreign corporations
engaged in a trade or business in the United States will be subject to a "branch
profits tax" on their "dividend equivalent amount" for the taxable year, which
will include exempt-interest dividends.  Certain Subchapter S corporations may
also be subject to taxes on their "passive investment income," which could
include exempt-interest dividends.  Up to 85% of the Social Security benefits or
railroad retirement benefits received by an individual during any taxable year
will be included in the gross income of such individual if the individual's
"modified adjusted gross income" (which includes exempt-interest dividends) plus
one-half of the Social Security benefits or railroad retirement benefits
received by such individual during that taxable year exceeds the base amount
described in Section 86 of the Code.

     Entities or persons who are "substantial users" (or persons related to
"substantial users") of facilities financed by industrial development bonds or
private activity bonds should consult their tax advisors before purchasing
shares of the Municipal Bond Portfolio or the Municipal Money Market Portfolio.
"Substantial user" is defined generally for these purposes as including a "non-
exempt person" who regularly uses in trade or business a part of a facility
financed from the proceeds of such bonds.

     Issuers of bonds purchased by the Municipal Bond Portfolio (or the
beneficiary of such bonds) may have made certain representations or covenants in
connection with the issuance of such bonds to satisfy certain requirements of
the Code that must be satisfied subsequent to the issuance of such bonds.
Investors should be aware that exempt-interest dividends derived from such bonds
may become subject to federal income taxation retroactively to the date thereof
if such representations are determined to have been inaccurate or if the issuer
of such bonds (or the beneficiary of such bonds) fails to comply with such
covenants.


           SPECIAL TAX CONSIDERATIONS RELATING TO FOREIGN INVESTMENTS

     Gains or losses attributable to foreign currency contracts, or to
fluctuations in exchange rates that occur between  the time a Portfolio accrues
interest or other receivables or accrues expenses or other liabilities
denominated in a foreign currency and the time the Portfolio actually collects
such receivables or pays such liabilities are treated as ordinary income or
ordinary loss to the Portfolio.  Similarly, gains or losses on disposition of
debt securities denominated in a foreign currency attributable to fluctuations
in the value of the foreign currency between the date of acquisition of the
security and the date of disposition also are treated as ordinary gain or loss
to the Portfolio.  These gains or losses increase or decrease the amount of a
Portfolio's net investment income available to be distributed to its
shareholders as ordinary income.

     It is expected that each Portfolio will be subject to foreign withholding
taxes with respect to its dividend and interest income from foreign countries,
and a Portfolio may be subject to foreign income taxes with respect to other
income.  So long as more than 50% in value of a Portfolio's total assets at the
close of the taxable year consists of stock or securities of foreign
corporations, the Portfolio may elect to treat certain foreign income taxes
imposed on it for United States federal income tax purposes as paid directly by
its shareholders.  A Portfolio will make such an election only if it deems it to
be in the best interest of its shareholders and will notify shareholders in
writing each year if it makes an election and of the amount of foreign income
taxes, if any, to be treated as paid by the shareholders.  If a Portfolio makes
the election, shareholders will be required to include in income their
proportionate shares of the amount of foreign income taxes treated as imposed on
the Portfolio and will be entitled to claim either a credit (subject to the
limitations discussed below) or, if they itemize deductions, a deduction, for
their shares of the foreign income taxes in computing their federal income tax
liability.

     Shareholders who choose to utilize a credit (rather than a deduction) for
foreign taxes will be subject to a number of complex limitations regarding the
availability and utilization of the credit.  Because of these limitations,
shareholders may be unable to claim a credit for the full amount of their
proportionate shares of the foreign income taxes paid by a Portfolio.
Shareholders are urged to consult their tax advisors regarding the application
of these rules to their particular circumstances.


                                       15
<PAGE>

                         TAXES AND FOREIGN SHAREHOLDERS

   
     Taxation of a shareholder who, as to the United States, is a nonresident
alien individual, a foreign trust or estate, a foreign corporation, or a foreign
partnership ("Foreign Shareholder") depends on whether the income from the
Portfolio is "effectively connected" with a U.S. trade or business carried on by
such shareholder.

     If the income from the Portfolio is not effectively connected with a U.S.
trade or business carried on by a Foreign Shareholder, distributions of net
investment income plus the excess of net  short-term capital gains over net
long-term capital losses will be subject to U.S. withholding tax at the rate of
30% (or such lower treaty rate as may be applicable) upon the gross amount of
the dividend.  Furthermore, Foreign Shareholders will generally be exempt from
U.S. federal income tax on gains realized on the sale of shares of the
Portfolio, distributions of net long-term capital gains, and amounts retained by
the Fund which are designated as undistributed capital gains.

     If the income from the Portfolio is effectively connected with a U.S. trade
or business carried on by a Foreign Shareholder, then distributions from the
Portfolio and any gains realized upon the sale of shares of the Portfolio, will
be subject to U.S. federal income tax at the rates applicable to U.S. citizens
and residents or domestic corporations.

     The Portfolio may be required to withhold U.S. federal income tax on
distributions that are otherwise exempt from withholding tax (or taxable at a
reduced treaty rate) unless the Foreign Shareholder complies with Internal
Revenue Service certification requirements.

     The tax consequences to a Foreign Shareholder entitled to claim the
benefits of an applicable tax treaty may differ from those described here.
Furthermore, Foreign Shareholders are strongly urged to consult their own tax
advisors with respect to the particular tax consequences to them of an
investment in a Portfolio, including the potential application of the provisions
of the Foreign Investment in Real Estate Property Tax Act of 1980, as amended.
    


                               PURCHASE OF SHARES

   
     The purchase price of the Class A shares of each Portfolio of the Fund,
except the Money Market and Municipal Money Market Portfolios, and the Class B
shares of each Multiclass Portfolio of the Fund is the net asset value next
determined after the order is received.  For each Portfolio of the Fund other
then the Money Market or Municipal Market Portfolios, an order received prior to
the regular close of the New York Stock Exchange (the "NYSE") will be executed
at the price computed on the date of receipt; and an order received after the
regular close of the NYSE will be executed at the price computed on the next day
the NYSE is open as long as the Fund's transfer agent receives payment by check
or in Federal Funds prior to the regular close of the NYSE on such day.  Shares
of the Money Market and Municipal Money Market Portfolios may be purchased at
the net asset value per share at the price next determined after Federal Funds
are available to such Portfolios.  Shares of the Fund may be purchased on any
day the NYSE is open.  The NYSE will be closed on the following days:  New
Year's Day, Presidents' Day, Good Friday, Memorial Day, Independence Day, Labor
Day, Thanksgiving Day and Christmas Day.
    

     Each Portfolio reserves the right in its sole discretion (i) to suspend the
offering of its shares, (ii) to reject purchase orders when in the judgment of
management such rejection is in the best interest of the Fund, and (iii) to
reduce or waive the minimum for initial and subsequent investments for certain
fiduciary accounts such as employee benefit plans or under circumstances where
certain economies can be achieved in sales of a Portfolio's shares.  The
International Equity Portfolio is currently limiting investments in the
Portfolio to: (i) reinvested dividends and distributions by existing
shareholders of the Portfolio; (ii) additional investments by existing
shareholders of the Portfolio; (iii) investments by employees of Morgan Stanley;
and (iv) investors who were in the process of becoming shareholders of the
Portfolio at the time the Portfolio limited further investments.


                              REDEMPTION OF SHARES

     Each Portfolio may suspend redemption privileges or postpone the date of
payment (i) during any period that the NYSE is closed, or trading on the NYSE is
restricted as determined by the Commission, (ii) during any period when an
emergency exists as defined by the rules of the Commission as a result of which
it is not reasonably practicable for a Portfolio to dispose of securities owned
by it, or fairly to determine the value of its assets, and (iii) for such other
periods as the Commission may permit.



                                       16
<PAGE>

     No charge is made by any Portfolio for redemptions except for the 1%
transaction fee assessed upon redemption of the International Small Cap
Portfolio.  Any redemption may be more or less than the shareholder's cost
depending on the market value of the securities held by the Portfolio.

     To protect your account and the Fund from fraud, signature guarantees are
required for certain redemptions.  Signature guarantees enable the Fund to
verify the identity of the person who has authorized a redemption from your
account.  Signature guarantees are required in connection with:  (1) all
redemptions, regardless of the amount involved, when the proceeds are to be paid
to someone other than the registered owner(s) and/or registered address; and
(2) share transfer requests.

     A guarantor must be a bank, a trust company, a member firm of a domestic
stock exchange, or a foreign branch of any of the foregoing.  Notaries public
are not acceptable guarantors.

     The signature guarantees must appear either:  (1) on the written request
for redemption; (2) on a separate instrument for assignment ("stock power")
which should specify the total number of shares to be redeemed; or (3) on all
stock certificates tendered for redemption and, if shares held by the Fund are
also being redeemed, on the letter or stock power.


                              SHAREHOLDER SERVICES

   
EXCHANGE FEATURES

     Shares of each Portfolio of the Fund may be exchanged for shares of any
other available Portfolio (other than the International Equity Portfolio, which
is closed to new investors).  In exchanging for shares of a Portfolio with more
than one class, the class of shares a shareholder receives in exchange will be
determined in the same manner as any other purchase of shares and will not be
based on the class of shares surrendered for the exchange.  Consequently, the
same minimum initial investment and minimum account size for determining the
class of shares received in the exchange will apply.

     Any such exchange will be based on the respective net asset values of the
shares involved.  There is no sales commission or charge of any kind.  Before
making an exchange, a shareholder should consider the investment objectives of
the Portfolio to be purchased.

     Exchange requests may be made either by mail or telephone.  Exchange
requests by mail should be sent to Morgan Stanley Institutional Fund, Inc., P.O.
Box 2798, Boston, Massachusetts 02208-2798. Telephone exchanges will be accepted
only if the certificates for the shares to be exchanged are held by the Fund for
the account of the shareholder and the registration of the two accounts will be
identical.  Requests for exchanges received prior to 10:00 a.m. (Eastern Time)
for the Municipal Money Market Portfolio, 11:00 a.m. (Eastern Time) for the
Money Market Portfolio, and 4:00 p.m. (Eastern Time) for the remaining
Portfolios will be processed as of the close of business on the same day.
Requests received after these times will be processed on the next business day.
Exchanges may be subject to limitations as to amounts or frequency, and to other
restrictions established by the Board of Directors to assure that such exchanges
do not disadvantage the Fund and its shareholders.

     For federal income tax purposes an exchange between Portfolios is a taxable
event for shareholders subject to tax, and, accordingly, a gain or loss may be
realized.  The exchange privilege may be modified or terminated by the Fund at
any time upon 60-days' notice to shareholders.

TRANSFER OF SHARES

     Shareholders may transfer shares of the Fund's Portfolios to another person
by making a written request to the Fund.  The request should clearly identify
the account and number of shares to be transferred, and include the signature of
all registered owners and all stock certificates, if any, which are subject to
the transfer.  The signature on the letter of request, the stock certificate or
any stock power must be guaranteed in the same manner as described under
"Redemption of Shares."  As in the case of redemptions, the written request must
be received in good order before any transfer can be made.  Transferring shares
may affect the eligibility of an account for a given class of the Portfolio's
shares and may result in involuntary conversion or redemption of such shares.
    


                                       17
<PAGE>

                             INVESTMENT LIMITATIONS

     Each current Portfolio has adopted the following restrictions which are
fundamental policies and may not be changed without the approval of the lesser
of:  (1) at least 67% of the voting securities of the Portfolio present at a
meeting if the holders of more than 50% of the outstanding voting securities of
the Portfolio are present or represented by proxy, or (2) more than 50% of the
outstanding voting securities of the Portfolio.  Each Portfolio of the Fund will
not:

     (1)  purchase or sell physical commodities unless acquired as a result of
ownership of securities or other instruments (except this shall not prevent the
Portfolio from purchasing or selling options or futures contracts or from
investing in securities or other instruments backed by physical commodities),
and except that the Gold Portfolio may invest in gold bullion in accordance with
its investment objectives and policies;

     (2)  purchase or sell real estate, although it may purchase and sell
securities of companies that deal in real estate and may purchase and sell
securities that are secured by interests in real estate;

     (3)  lend any security or make any other loan if, as a result, more than 
33 1/3% of its total assets would be lent to other parties, but this limitation
does not apply to purchases of debt securities or repurchase agreements;

   
     (4)  except with respect to the Global Fixed Income, Emerging Markets,
Emerging Markets Debt, China Growth, Latin American, MicroCap, Aggressive
Equity, U.S. Real Estate Portfolios (i) purchase more than 10% of any class of
the outstanding voting securities of any issuer and (ii) purchase securities of
an issuer (except obligations of the U.S. Government and its agencies and
instrumentalities) if as a result, with respect to 75% of its total assets, more
than 5% of the Portfolio's total assets, at market value, would be invested in
the securities of such issuer;

     (5)  issue senior securities and will not borrow, except from banks and as
a temporary measure for extraordinary or emergency purposes and then, in no
event, in excess of 33 1/3% of its total assets (including the amount borrowed)
less liabilities (other than borrowings), except that each of the Emerging
Markets Debt and Latin American Portfolios may borrow from banks and other
entities in amount not in excess of 33 1/3% of its total assets (including the
amount borrowed) less liabilities in accordance with its investment objectives
and policies;
    

     (6)  underwrite securities issued by others, except to the extent that the
Portfolio may be considered an underwriter within the meaning of the 1933 Act in
the disposition of restricted securities;

     (7)  acquire any securities of companies within one industry if, as a
result of such acquisition, more than 25% of the value of the Portfolio's total
assets would be invested in securities of companies within such industry;
provided, however, that there shall be no limitation on the purchase of
obligations issued or guaranteed by the U.S. Government, its agencies or
instrumentalities, or (in the case of the Money Market Portfolio or the
Municipal Money Market Portfolio) instruments issued by U.S. Banks, except that
the Latin American Portfolio may invest more than 25% of its total assets in
companies involved in the telecommunications industry or financial services
industry, and except that the U.S. Real Estate Portfolio may invest more than
25% of its total assets in the U.S. real estate industry, respectively, as
provided in their respective Prospectuses;  and

     (8)  write or acquire options or interests in oil, gas or other mineral
exploration or development programs.

     In addition, each current Portfolio of the Fund has adopted non-fundamental
investment limitations as stated below and in their respective Prospectuses.
Such limitations may be changed without shareholder approval.  Each current
Portfolio of the Fund will not:

     (1)  purchase on margin or sell short, except (i) that the Emerging Markets
Debt, Latin American and Aggressive Equity Portfolios may from time to time sell
securities short without limitation but consistent with applicable legal
requirements as stated in its Prospectus, (ii) that each of the Active Country
Allocation, Equity Growth, Gold, China Growth and Aggressive Equity Portfolios
may enter into option transactions to the extent that not more than 5% of the
Portfolio's total assets are required as deposits to secure obligations under
options and not more than 20% of its total assets are invested in options,
futures contracts and options on futures contracts at any time, and (iii) as
specified above in Fundamental Restriction No. (1);

     (2)  purchase or retain securities of an issuer if those Officers and
Directors of the Fund or its investment adviser owning more than 1/2 of 1% of
such securities together own more than 5% of such securities;


                                       18
<PAGE>

     (3)  pledge, mortgage, or hypothecate any of its assets to an extent
greater than 10% of its total assets at fair market value;

     (4)  invest for the purpose of exercising control over management of any
company;

     (5)  invest its assets in securities of any investment company, except by
purchase in the open market involving only customary brokers' commissions or in
connection with mergers, acquisitions of assets or consolidations and except as
may otherwise be permitted by the 1940 Act;

     (6)  invest more than 5% of its total assets in securities of companies
which have (with predecessors) a record of less than three years' continuous
operation;

     (7)  purchase warrants if, by reason of such purchase, more than 5% of the
value of the Portfolio's net assets (taken at market value) would be invested in
warrants, valued at the lower of cost or market.  Included within this amount,
but not to exceed 2% of the value of the Portfolio's net assets, may be warrants
that are not listed on a recognized stock exchange;

     (8)  except for the U.S. Real Estate Portfolio, invest in real estate
limited partnership interests, and the U.S. Real Estate Portfolio may not invest
in such interests that are not publicly traded;

     (9)  make loans except (i) by purchasing bonds, debentures or similar
obligations (including repurchase agreements, subject to the limitations as
described in the respective Prospectuses) that are publicly distributed, and
(ii) by lending its portfolio securities to banks, brokers, dealers and other
financial institutions so long as such loans are not inconsistent with the 1940
Act or the Rules and Regulations or interpretations of the Commission
thereunder;

     (10) invest in oil, gas or other mineral leases; and

     (11) purchase puts, calls, straddles, spreads and any combination thereof
if for any reason thereof the value of its aggregate investment in such classes
of securities will exceed 5% of their respective total assets, except that each
of the Active Country Allocation, Equity Growth, Gold, China Growth and
Aggressive Equity Portfolios may enter into option transactions to the extent
that not more than 5% of the Portfolio's total assets are required as deposits
to secure obligations under options and not more than 20% of its total assets
are invested in options, futures contracts and options on futures contracts at
any time.

     The Balanced, Fixed Income and Value Equity Portfolios will only issue
shares for securities or assets other than cash in a bona fide reorganization,
statutory merger, or in other acquisitions of portfolio securities (except for
municipal debt securities issued by state political subdivisions or their
agencies or instrumentalities) which (i) meet their respective investment
objectives;  (ii) are acquired for investment and not for resale.

     Each of the Global Fixed Income, Emerging Markets, Emerging Markets Debt,
China Growth, Latin American, Aggressive Equity and U.S. Real Estate Portfolios
will diversify its holdings so that, at the close of each quarter of its taxable
year, (i) at least 50% of the market value of the Portfolio's total assets is
represented by cash (including cash items and receivables), U.S. Government
securities, and other securities, with such other securities limited, in respect
of any one issuer, for purposes of this calculation to an amount not greater
than 5% of the value of the Portfolio's  total assets and 10% of the outstanding
voting securities of such issuer, and (ii) not more than 25% of the value of its
total assets is invested in the securities of any one issuer (other than U.S.
Government securities).

     The percentage limitations contained in these restrictions apply at the
time of purchase of securities.  Future Portfolios of the Fund may adopt
different limitations.


                  DETERMINING MATURITIES OF CERTAIN INSTRUMENTS

     Generally, the maturity of a portfolio instrument shall be deemed to be the
period remaining until the date noted on the face of the instrument as the date
on which the principal amount must be paid, or in the case of an instrument
called for redemption, the date on which the redemption payment must be made.
However, instruments having variable or floating interest rates or demand
features may be deemed to have remaining maturities as follows:  (1) a
Government Obligation with a variable rate of interest readjusted no less
frequently than annually may be deemed to have a maturity equal to the period
remaining until the next readjustment of the interest rate; (b) an instrument
with a variable rate of interest, the principal amount of which is scheduled on
the face of the


                                       19
<PAGE>

instrument to be paid in one year or less, may be deemed to have a maturity
equal to the period remaining until the next readjustment of the interest rate;
(c) an instrument with a variable rate of interest that is subject to a demand
feature may be deemed to have a maturity equal to the longer of the period
remaining until the next readjustment of the interest rate or the period
remaining until the principal amount can be recovered through demand; (d) an
instrument with a floating rate of interest that is subject to a demand feature
may be deemed to have a maturity equal to the period remaining until the
principal amount can be recovered through demand; and (e) a repurchase agreement
may be deemed to have a maturity equal to the period remaining until the date on
which the repurchase of the underlying securities is scheduled to occur, or
where no date is specified, but the agreement is subject to demand, the notice
period applicable to a demand for the repurchase of the securities.


                             MANAGEMENT OF THE FUND

OFFICERS AND DIRECTORS

     The Fund's officers, under the supervision of the Board of Directors,
manage the day-to-day operations of the Fund.  The Directors set broad policies
for the Fund and choose its officers.  Three Directors and all of the officers
of the Fund are directors, officers or employees of the Fund's adviser,
distributor or administrative services provider.  Directors and officers of the
Fund are also directors and officers of some or all of the other investment
companies managed, administered, advised or distributed by Morgan Stanley Asset
Management Inc. or its affiliates.  The other Directors have no affiliation with
the Fund's adviser, distributor or administrative services provider.  A list of
the Directors and officers of the Fund and a brief statement of their present
positions and principal occupations during the past five years is set forth
below:


   
Name, Address              Position        Principal Occupation During
and Age                    with Fund              Past Five Years
- -------------------        ---------       ---------------------------

Barton M. Biggs*          Chairman and     Chairman and Director of Morgan
1221 Avenue of the        Director         Stanley Asset Management Inc. and
Americas                                   Morgan Stanley Asset Management
New York, NY 10020                         Limited; Managing Director of Morgan
(63)                                       Stanley & Co., Inc.; Director of
                                           Morgan Stanley Group Inc.; Member of
                                           International Advisory Counsel of
                                           the Thailand Fund; Chairman and
                                           Director of The Brazilian Investment
                                           Fund, Inc., The Latin American
                                           Discovery Fund, Inc., The Malaysia
                                           Fund, Inc., Morgan Stanley Africa
                                           Investment Fund, Inc., Morgan Stanley
                                           Asia-Pacific Fund, Inc., Morgan
                                           Stanley Emerging Markets Debt Fund,
                                           Inc., Morgan Stanley Emerging Markets
                                           Fund, Inc., Morgan Stanley Fund Inc.,
                                           Morgan Stanley Global Opportunity
                                           Bond Fund, Inc., Morgan Stanley High
                                           Yield Fund, Inc., Morgan Stanley
                                           India Investment Fund, Inc., Morgan
                                           Stanley Institutional Fund, Inc., The
                                           Pakistan Investment Fund, Inc., PCS
                                           Cash Fund, Inc., The Thai Fund, Inc.
                                           and The Turkish Investment Fund, Inc.
    


                                       20
<PAGE>

   
Name, Address              Position        Principal Occupation During
and Age                    with Fund              Past Five Years
- -------------------        ---------       ---------------------------

Warren J. Olsen*           Director and    Principal of Morgan Stanley & Co.,
1221 Avenue of the         President       Inc.; Principal of Morgan Stanley
Americas                                   Asset Management Inc.; President and
New York, NY 10020                         Director of The Brazilian Investment
(39)                                       Fund, Inc., The Latin American
                                           Discovery Fund, Inc., The Malaysia
                                           Fund, Inc., Morgan Stanley Africa
                                           Investment Fund, Inc., Morgan Stanley
                                           Asia-Pacific Fund, Inc., Morgan
                                           Stanley Emerging Markets Debt Fund,
                                           Inc., Morgan Stanley Emerging Markets
                                           Fund, Inc., Morgan Stanley Fund,
                                           Inc., Morgan Stanley Global
                                           Opportunity Bond Fund, Inc., Morgan
                                           Stanley High Yield Fund, Inc., Morgan
                                           Stanley India Investment Fund, Inc.,
                                           Morgan Stanley Institutional Fund,
                                           Inc., The Pakistan Investment Fund,
                                           Inc., PCS Cash Fund, Inc., The Thai
                                           Fund, Inc., and The Turkish
                                           Investment Fund, Inc.

John D. Barrett, II        Director        Chairman and Director of Barrett
521 Fifth Avenue                           Associates, Inc. (investment
New York, NY 10135                         counseling); Director of the Ashforth
(60)                                       Company (real estate); Director of
                                           the Morgan Stanley Fund, Inc., Morgan
                                           Stanley Institutional Fund, Inc. and
                                           PCS Cash Fund, Inc.

Gerard E. Jones            Director        Partner in Richards & O'Neil LLP (law
43 Arch Street                             firm); Director of the Morgan Stanley
Greenwich, CT 06830                        Fund, Inc., Morgan Stanley
(59)                                       Institutional Fund, Inc. and PCS Cash
                                           Fund, Inc.

Andrew McNally IV          Director        Chairman and Chief Executive Officer
8255 North Central                         of Rand McNally (publication);
Park Avenue                                Director of Allendale Insurance Co.,
Skokie, IL 60076                           Mercury Finance (consumer finance);
(56)                                       Zenith Electronics, Hubbell, Inc.
                                           (industrial electronics); Director of
                                           the Morgan Stanley Fund, Inc., Morgan
                                           Stanley Institutional Fund, Inc. and
                                           PCS Cash Fund, Inc.

Samuel T. Reeves           Director        Chairman of the Board and CEO,
8211 North                                 Pinacle L.L.C. (investment firm);
Fresno Street                              Director, Pacific Gas and Electric
Fresno, CA 93720                           and PG&E Enterprises (utilities);
(61)                                       Director of the Morgan Stanley Fund,
                                           Inc., Morgan Stanley Institutional
                                           Fund, Inc. and PCS Cash Fund, Inc.
    


                                       21

<PAGE>

   
Name, Address              Position        Principal Occupation During
and Age                    with Fund              Past Five Years
- -------------------        ---------       ---------------------------

Fergus Reid                Director        Chairman and Chief Executive Officer
85 Charles Colman Blvd                     of LumeLite Corporation (injection
Pawling, NY 12564                          molding firm); Trustee and Director
(63)                                       of Vista Mutual Fund Group; Director
                                           of the Morgan Stanley Fund, Inc.,
                                           Morgan Stanley Institutional Fund,
                                           Inc. and PCS Cash Fund, Inc.

Frederick O. Robertshaw    Director        Of Counsel, Bryan, Cave (law firm);
2800 North Central Avenue                  Previously associated with Copple,
Phoenix, AZ 85004                          Chamberlin & Boehm, P.C. and Rake,
(62)                                       Copple, Downey & Black, P.C. (law
                                           firms); Director of the Morgan
                                           Stanley Fund, Inc., Morgan Stanley
                                           Institutional Fund, Inc. and PCS Cash
                                           Fund, Inc.

Frederick B. Whittemore*   Director        Advisory Director of Morgan Stanley &
1251 Avenue of the                         Co., Inc.; Vice-Chairman and Director
Americas, 30th Flr.                        of The Brazilian Investment Fund,
New York, NY 10020                         Inc., The Latin American Discovery
(65)                                       Fund, Inc., The Malaysia Fund, Inc.,
                                           Morgan Stanley Africa Investment
                                           Fund, Inc., Morgan Stanley
                                           Asia-Pacific Fund, Inc., Morgan
                                           Stanley Emerging Markets Debt Fund,
                                           Inc., Morgan Stanley Emerging Markets
                                           Fund, Inc., Morgan Stanley Fund,
                                           Inc., Morgan Stanley Global
                                           Opportunity Bond Fund, Inc., Morgan
                                           Stanley High Yield Fund,Inc., Morgan
                                           Stanley India Investment Fund, Inc.,
                                           Morgan Stanley Institutional Fund,
                                           Inc., The Pakistan Investment Fund,
                                           Inc., PCS Cash Fund, Inc., The Thai
                                           Fund, Inc. and The Turkish Investment
                                           Fund, Inc.

James W. Grisham*          Vice President  Principal of Morgan Stanley & Co.,
1221 Avenue of the                         Inc.; Principal of Morgan Stanley
Americas                                   Asset Management Inc.; Vice President
New York, NY 10020                         of The Brazilian Investment Fund,
(54)                                       Inc., The Latin American Discovery
                                           Fund, Inc., The Malaysia Fund, Inc.,
                                           Morgan Stanley Africa Investment
                                           Fund, Inc., Morgan Stanley
                                           Asia-Pacific Fund, Inc., Morgan
                                           Stanley Emerging Markets Debt Fund,
                                           Inc., Morgan Stanley Emerging Markets
                                           Fund, Inc., Morgan Stanley Fund,
                                           Inc., Morgan Stanley Global
                                           Opportunity Bond Fund, Inc., Morgan
                                           Stanley High Yield Fund, Inc., Morgan
                                           Stanley India Investment Fund, Inc.,
                                           Morgan Stanley Institutional Fund,
                                           Inc., The Pakistan Investment Fund,
                                           Inc., PCS Cash Fund, Inc., The Thai
                                           Fund, Inc. and The Turkish Investment
                                           Fund, Inc.
    


                                       22
<PAGE>

   
Name, Address              Position        Principal Occupation During
and Age                    with Fund              Past Five Years
- -------------------        ---------       ---------------------------

Harold J. Schaaff, Jr.*    Vice President  Principal of Morgan Stanley & Co.;
1221 Avenue of the                         General Counsel and Secretary of
Americas                                   Morgan Stanley Asset Management Inc.;
New York, NY 10020                         Vice President of The Brazilian
(35)                                       Investment Fund, Inc., The Latin
                                           American Discovery Fund, Inc., The
                                           Malaysia Fund, Inc., Morgan Stanley
                                           Africa Investment Fund, Inc., Morgan
                                           Stanley Asia-Pacific Fund, Inc.,
                                           Morgan Stanley Emerging Markets Debt
                                           Fund, Inc., Morgan Stanley Emerging
                                           Markets Fund, Inc., Morgan Stanley
                                           Fund, Inc., Morgan Stanley Global
                                           Opportunity Bond Fund, Inc., Morgan
                                           Stanley High Yield Fund, Inc., Morgan
                                           Stanley India Investment Fund, Inc.,
                                           Morgan Stanley Institutional Fund,
                                           Inc., The Pakistan Investment Fund,
                                           Inc., PCS Cash Fund, Inc., The Thai
                                           Fund, Inc. and The Turkish Investment
                                           Fund, Inc.


Joseph P. Stadler*         Vice President  Vice President of Morgan Stanley 
1221 Avenue of the                         Asset  Management Inc.; Previously
Americas                                   with Price Waterhouse LLP 
New York, NY 10020                         (accounting); Vice President of The
(41)                                       Brazilian Investment Fund, Inc., The
                                           Latin American Discovery Fund, Inc.,
                                           The Malaysia Fund, Inc., Morgan 
                                           Stanley Africa Investment Fund, Inc.,
                                           Morgan Stanley Asia-Pacific Fund, 
                                           Inc., Morgan Stanley Emerging Markets
                                           Debt Fund, Inc., Morgan Stanley 
                                           Emerging Markets Fund, Inc., Morgan 
                                           Stanley Fund, Inc., Morgan Stanley 
                                           Global Opportunity Bond Fund, Inc., 
                                           Morgan Stanley High Yield Fund, Inc.,
                                           Morgan Stanley India Investment Fund,
                                           Inc., Morgan Stanley Institutional 
                                           Fund, Inc., The Pakistan Investment 
                                           Fund, Inc., PCS Cash Fund, Inc., The
                                           Thai Fund, Inc. and The Turkish 
                                           Investment Fund, Inc.
    


                                       23
<PAGE>

   
Name, Address              Position        Principal Occupation During
and Age                    with Fund              Past Five Years
- -------------------        ---------       ---------------------------

Valerie Y. Lewis*          Secretary       Vice President of Morgan Stanley 
1221 Avenue of the                         Asset Management Inc.; Previously 
Americas                                   with Citicorp (banking); Secretary of
New York, NY 10020                         The Brazilian Investment Fund, Inc.,
(40)                                       The Latin American Discovery Fund,
                                           Inc., The Malaysia Fund, Inc., Morgan
                                           Stanley Africa Investment Fund, Inc.,
                                           Morgan Stanley Asia-Pacific Fund,
                                           Inc., Morgan Stanley Emerging Markets
                                           Debt Fund, Inc., Morgan Stanley
                                           Emerging Markets Fund, Inc., Morgan
                                           Stanley Fund, Inc., Morgan Stanley
                                           Global Opportunity Bond Fund, Inc.,
                                           Morgan Stanley High Yield Fund, Inc.,
                                           Morgan Stanley India Investment Fund,
                                           Inc., Morgan Stanley Institutional
                                           Fund, Inc., The Pakistan Investment
                                           Fund, Inc., PCS Cash Fund, Inc., The
                                           Thai Fund, Inc. and The Turkish
                                           Investment Fund, Inc.

Karl O. Hartmann           Assistant       Senior Vice President, Secretary and
73 Tremont Street          Secretary       General Counsel of Chase Global Funds
Boston, MA 02108-3913                      Services Company; Previously, Leland,
(41)                                       O'Brien, Rubinstein Associates, Inc.
                                           (investments).

James R. Rooney            Treasurer       Vice President, Chase Global Funds
73 Tremont Street                          Services Company; Director of Fund
Boston, MA 02108-3913                      Administration; Officer of various
(37)                                       investment companies managed by 
                                           Morgan Stanley Asset Management Inc.;
                                           Previously with Scudder, Stevens &
                                           Clark, Inc. (investments) and Ernst &
                                           Young LLP (accounting); Treasurer of
                                           The Brazilian Investment Fund, Inc.,
                                           The Latin American Discovery Fund,
                                           Inc., The Malaysia Fund, Inc., Morgan
                                           Stanley Africa Investment Fund, Inc.,
                                           Morgan Stanley Asia-Pacific Fund,
                                           Inc., Morgan Stanley Emerging Markets
                                           Debt Fund, Inc., Morgan Stanley
                                           Emerging Markets Fund, Inc., Morgan
                                           Stanley Fund, Inc., Morgan Stanley
                                           Global Opportunity Bond Fund, Inc.,
                                           Morgan Stanley High Yield Fund, Inc.,
                                           Morgan Stanley India Investment Fund,
                                           Inc., Morgan Stanley Institutional
                                           Fund, Inc., The Pakistan Investment
                                           Fund, Inc., The Thai Fund, Inc. and
                                           The Turkish Investment Fund, Inc.
    


                                       24
<PAGE>

   
Name, Address              Position        Principal Occupation During
and Age                    with Fund              Past Five Years
- -------------------        ---------       ---------------------------

Joanna Haigney             Assistant       Supervisor of Fund Administration and
73 Tremont Street          Treasurer       Compliance, Chase Global Funds
Boston, MA 02108-3913                      Services Company; Previously with
(29)                                       Coopers & Lybrand LLP; Assistant
                                           Treasurer of The Brazilian Investment
                                           Fund, Inc., The Latin American
                                           Discovery Fund, Inc., The Malaysia
                                           Fund, Inc., Morgan Stanley Africa
                                           Investment Fund, Inc., Morgan Stanley
                                           Asia-Pacific Fund, Inc., Morgan
                                           Stanley Emerging Markets Debt Fund,
                                           Inc., Morgan Stanley Emerging Markets
                                           Fund, Inc., Morgan Stanley Fund, 
                                           Inc., Morgan Stanley Global 
                                           Opportunity Bond Fund, Inc., Morgan
                                           Stanley High Yield Fund, Inc., Morgan
                                           Stanley India Investment Fund, Inc., 
                                           Morgan Stanley Institutional Fund, 
                                           Inc., The Pakistan Investment Fund, 
                                           Inc., The Thai Fund, Inc. and The 
                                           Turkish Investment Fund, Inc.


- --------------

*    "Interested Person" within the meaning of the 1940 Act.
    

REMUNERATION OF DIRECTORS AND OFFICERS

   

     Effective June 28, 1995, the Open-end Fund Complex will pay each of the 
nine Directors who is not an "interested person" an annual aggregate fee of 
$55,000, plus out-of-pocket expenses.  The Open-end Fund Complex will pay 
each of the members of the Fund's Audit Committee, which consists of the 
Fund's Directors who are not "interested persons," an additional annual 
aggregate fee of $10,000 for serving on such a committee.  The allocation of 
such fees will be among the three funds in the Open-end Fund Complex in 
direct proportion to their respective average net assets.  For the fiscal 
year December 31, 1995, the Fund paid approximately $244,000 in Directors' 
fees and expenses.  Directors who are also officers or affiliated persons 
receive no remuneration for their services as Directors.  The Fund's officers 
and employees are paid by the Adviser or its agents.  As of March 31, 1996, 
to Fund management's knowledge, the Directors and officers of the Fund, as a 
group, owned more than 1% of the outstanding common stock of the following 
Portfolios of the Fund:  2.4% Active Country Allocation Portfolio - Class B 
shares; 1.7% Aggressive Equity Portfolio - Class B shares; 1.7% Asian Equity 
Portfolio - Class A shares; 1.8% Emerging Growth Portfolio -Class B shares; 
1.0% Emerging Markets Portfolio - Class B shares; 2.0% Equity Growth 
Portfolio - Class B shares; 3.3% Gold Portfolio - Class B shares; 1.3% 
International Equity Portfolio - Class B shares and 4.8% Latin American 
Portfolio - Class A shares.  The following table shows aggregate compensation 
paid to each  of the Fund's Directors by the Fund and the Fund Complex, 
respectively, in the fiscal year ended December 31, 1995.

    

                                       25

<PAGE>

                               COMPENSATION TABLE
   

<TABLE>
<CAPTION>

- ----------------------------------------------------------------------------------------------------------------------------------
- ----------------------------------------------------------------------------------------------------------------------------------

     (1)                           (2)                        (3)                       (4)                      (5)
     NAME OF                       AGGREGATE                  PENSION OR                ESTIMATED                TOTAL
     PERSON,                       COMPENSATION               RETIREMENT                ANNUAL                   COMPENSATION
     POSITION                      FROM                       BENEFITS ACCRUED          BENEFITS                 FROM REGISTRANT
                                   REGISTRANT                 AS PART OF FUND           UPON                     AND FUND COMPLEX
                                                              EXPENSES                  RETIREMENT               PAID TO DIRECTORS

- ----------------------------------------------------------------------------------------------------------------------------------
- ----------------------------------------------------------------------------------------------------------------------------------
<S>                                <C>                        <C>                       <C>                      <C>
Barton M. Biggs,                         N/A                                                                                  N/A
Director and Chairman
of the Board

Warren J. Olsen,                         N/A                                                                                  N/A
Director and President

John D. Barrett, II                   14,085                                                                               26,405
Director

Gerard E. Jones,                      25,335                                                                               79,655
Director

Andrew McNally, IV                    11,916                                                                               32,834
Director

Samuel T. Reeves,                     11,916                                                                               14,303
Director

Fergus Reid,                          14,085                                                                               48,517
Director

Frederick O. Robertshaw,              11,916                                                                               36,055
Director

Frederick B. Whittemore,              12,150                                                                               41,429
Director

John P. Britton*,                     11,250                                                                               11,250
Director

George R. Bunn*,                      12,900                                                                               12,900
Director

Peter E. deSvastich*,                 11,250                                                                               25,225
Director
</TABLE>

- --------------

* As of June 30, 1995, Mssrs. Britton, Bunn and deSvastich resigned from the
  Board of Directors.

    

                                       26
<PAGE>


INVESTMENT ADVISORY AND ADMINISTRATIVE AGREEMENTS

   

       Morgan Stanley Asset Management Inc. ("MSAM" or the "Adviser") is a
wholly-owned subsidiary of Morgan Stanley Group Inc.  The principal offices of
Morgan Stanley Group Inc. are located at 1221 Avenue of the Americas, New York,
NY 10020.  As compensation for advisory services for the fiscal years ended
December 31, 1993, December 31, 1994 and December 31, 1995, the Adviser earned
fees of approximately $17,539,000, $34,338,000 and $40,534,000, respectively,
and from such fees voluntarily waived fees of $3,037,000, $2,640,000 and
$3,526,000, respectively.  For the fiscal years ended December 31, 1993,
December 31, 1994 and December 31, 1995, the Fund paid brokerage commissions of
approximately $5,827,000, $7,287,293 and $10,317,515, respectively.  For the
fiscal years ended December 31, 1993, December 31, 1994 and December 31, 1995,
the Fund paid in the aggregate $797,000, $796,000 and $377,000, respectively, as
brokerage commissions to Morgan Stanley & Co. Incorporated, an affiliated
broker-dealer, which represented 13%, 11% and 4% of the total amount of
brokerage commissions paid in each respective period.  For the fiscal years
ended December 31, 1993 , December 31, 1994 and December 31, 1995, the Fund paid
administrative fees to MSAM of approximately $4,662,000, $4,458,000 and
$5,238,000, respectively.

       The Sub-Adviser, Sun Valley Gold Company, with principal offices at 620
Sun Valley Road, Sun Valley, Idaho, serves as the investment sub-adviser of the
Gold Portfolio, pursuant to a sub-advisory agreement among the Fund, the Adviser
and the Sub-Adviser (the "Sub-Advisory Agreement").  The Adviser and the Sub-
Adviser have entered into an indemnification agreement under which, generally,
the Sub-Adviser has agreed to indemnify the Adviser and the Fund for claims or
losses in connection with any failure by the Sub-Adviser to comply with its
obligations under the Sub-Advisory Agreement or related agreements or any act or
omission that amounts to negligence, misfeasance or bad faith, and the Adviser
has agreed to indemnify the Sub-Adviser for claims or losses in connection with
any failure by the Adviser to comply with its obligations under the Sub-Advisory
Agreement or related agreements.  As compensation for sub-advisory services for
the fiscal years ended December 31, 1994 and December 31, 1995, the Sub-Adviser
earned fees of approximately $76,000 and $73,000, respectively, and from such
fees voluntarily waived fees of $36,000 and $37,000, respectively.  For the
fiscal years ended December 31, 1994 and December 31, 1995, the Fund paid $8,000
and $450, respectively, as brokerage commissions to Sun Valley.

       Pursuant to the MSAM Administration Agreement between the Adviser and
the Fund, the Adviser provides Administrative Services.  For its services under
the Administration Agreement, the Fund pays the Adviser a monthly fee which on
an annual basis equals 0.15 of 1% of the average daily net assets of each
Portfolio.

       Under the Agreement between the Adviser and The Chase Manhattan Bank,
N.A. ("Chase," successor in interest to United States Trust Company of New
York), Chase Global Funds Services Company ("CGFSC," formerly Mutual Funds
Service Company and now a Chase subsidiary) provides certain administrative
services to the Fund.  CGFSC provides operational and administrative services to
investment companies with approximately $62 billion in assets and having
approximately 187,286 shareholder accounts as of March 31, 1996.  CGFSC's
business address is 73 Tremont Street, Boston, Massachusetts 02108-3913.

    

DISTRIBUTION OF FUND SHARES

   

       Morgan Stanley & Co. Incorporated (the "Distributor"), a wholly-owned
subsidiary of Morgan Stanley Group Inc., serves as the Distributor of the Fund's
shares pursuant to a Distribution Agreement for the Fund and a Plan of
Distribution for the Class B shares of the Portfolios (except the International
Small Cap Portfolio which does not have Class B shares) pursuant to Rule 12b-1
under the 1940 Act (each, a "Plan" and collectively, the "Plans").  Under each
Plan the Distributor is entitled to receive from these Portfolios a distribution
fee, which is accrued daily and paid quarterly, at an annual rate of up to 0.25%
of the average daily net assets of the Class B shares of these Portfolios.  The
Distributor expects to allocate most of its fee to its investment representative
and investment dealers, banks or financial service firms that provide
distribution services ("Participating Dealer").  The actual amount of such
compensation is agreed upon by the Fund's Board of Directors and by the
Distributor.  The Distributor may, in its discretion, voluntarily waive from
time to time all or any portion of its distribution fee and the Distributor is
free to make additional payments out of its own assets to promote the sale of
Fund shares.

       The Plans obligate the Portfolios to accrue and pay to the Distributor
the fee agreed to under its Distribution Agreement. The Plans do not obligate
the Portfolios to reimburse the Distributor for the actual expenses the
Distributor may incur in fulfilling its obligations under the Plans.  Thus,
under each Plan, even if the Distributor's actual expenses exceed the fee
payable to it thereunder at any given time, the Portfolios will not be obligated
to pay more than that fee. If the Distributor's actual expenses are less than
the fee it receives, the Distributor will retain the full amount of the fee. The
Plans for the Class B shares were most recently approved by the Fund's Board of
Directors, including those directors who are not "interested persons" of the
Fund as that term is defined in the 1940 Act and who have no direct or indirect
financial interest in the operation of a Plan or in any agreements related
thereto, on September 20, 1995.

    

                                          27

<PAGE>

   
       The Class B shares commenced operations on January 2, 1996. Therefore,
no Rule 12b-1 fees were paid to the Distributor for the fiscal year ended
December 31, 1995.  The Mortgage-Backed Securities, China Growth, MicroCap and
International Magnum Portfolios were not in operation in the fiscal year ended
December 31, 1995.
    

CODE OF ETHICS

       The Board of Directors of the Fund has adopted a Code of Ethics under
Rule 17j-1 of the 1940 Act which incorporates the Code of Ethics of the Adviser
(together, the "Codes").  The Codes significantly restrict the personal
investing activities of all employees of the Adviser and, as described below,
impose additional, more onerous, restrictions on the Fund's investment
personnel.

       The Codes require that all employees of the Adviser preclear any
personal securities investment (with limited exceptions, such as government
securities).   The preclearance requirement and associated procedures are
designed to identify any substantive prohibition or limitation applicable to the
proposed investment.  The substantive restrictions applicable to all employees
of the Adviser include a ban on acquiring any securities in a "hot" initial
public offering and a prohibition from profiting on short-term trading in
securities.  In addition, no employee may purchase or sell any security that at
the time is being purchased or sold (as the case may be), or to the knowledge of
the employee is being considered for purchase or sale, by any fund advised by
the Adviser.  Furthermore, the Codes provide for trading "blackout periods" that
prohibit trading by investment personnel of the Fund within periods of trading
by the Fund in the same (or equivalent) security.

CONTROL PERSONS AND PRINCIPAL HOLDERS OF SECURITIES

   
       The names and addresses of the holders of 5% or more of the outstanding
shares of any class of the Fund as of March 31, 1996 and the percentage of
outstanding shares of such classes owned beneficially or of record by such
shareholders as of such date are, to Fund management's knowledge, as follows:
    

   
ACTIVE COUNTRY ALLOCATION PORTFOLIO:  The Trustees of Columbia University in the
City of New York, 475 Riverside Drive, Suite 401, New York, NY 10115, owned 15%
of such Portfolio's total outstanding Class A shares.
    

   
City of New York Deferred Compensation Plan, 40 Rector Street, 3rd Floor, New
York, NY 10006, owned 16% of such Portfolio's total outstanding Class A shares.
    

   
Oglebay Norton Company, 1100 Superior Avenue, Cleveland, OH 44114-2598, owned
11% of such Portfolio's total outstanding Class A shares.
    

   
The Finn Foundation, Northern Trust Co., Master Trust Dept., P.O. Box 92984,
Chicago, IL 60675, owned 7% of such Portfolio's total outstanding Class A
shares.
    

   
Strafe & Co., F/A/O/ in Thompson Consumer Electronics, 235 West Schrock Road,
Westerville, OH 43081, owned 7% of such Portfolio's total outstanding Class A
shares.
    

   
Sahara Enterprises, Inc., 3 First National Plaza, Suite 2000, Chicago,
IL 60602-4260, owned 6% of such Portfolio's total outstanding Class A shares.
    

   
Jeffrey R. Holzschuh, 66 Sawmill Lane, Greenwich, CT 06830-4046, owned 14% of
such Portfolio's total outstanding Class B shares.
    

   
Benefit Administrators of America Inc., Attn:  John Stephens, 626 Grand Avenue,
Des Moines, IA  50309, owned 14% of such Portfolio's total outstanding Class B
shares.
    

   
David Johnson and Audrey E. Johnson, 405 East Winchester, Libertyville, IL
60048-1677, owned 10% of such Portfolio's total outstanding Class B shares.
    

   
Mercury & Co., C/O Investors Bank & Trust Company, P.O. Box 1537 Top 57, Boston,
MA  02205-1537, owned 8% of such Portfolio's total outstanding Class B shares.
    

   
John P. and Janet K. Hanlon, 7 Stafford Place, Towaco, NJ 07082, owned 7% of
such Portfolio's total outstanding Class B shares.
    


                                          28

<PAGE>

   

Michael and Maureen Cassedy, 1221 Jones Street, Apt. D1, San Francisco, CA
94109-4228, owned 7% of such Portfolio's total outstanding Class B shares.

Guarantee & Trust Company, IRA R/O, 101 S. Spring Street, La Grange, IL  60525,
owned 6% of such Portfolio's total outstanding Class B shares.

AGGRESSIVE EQUITY PORTFOLIO:  Valassis Enterprises - Equity C/O Franklin
Enterprises, 520 Lake Cook Road, Suite 380, Deerfield, IL 60015, owned 15% of
such Portfolio's total outstanding Class A shares.

Kinghugh S.A., C/O Office of Directors, Chin Lan Building, 306 Tun Hwa Road,
South Taipei, owned 10% of such Portfolio's total outstanding Class A shares.

Hullbridge Investement Limited, The Tropic Isle Building, Wickahams Cay Tortola,
British Virgin Islands, owned 8% of such Portfolio's total outstanding Class A
shares.

Guy L. Chazal, Morgan Stanley & Company, 1221 Avenue of the Americas - 33rd
floor, New York, NY  10020, owned 8% of such Portfolio's total outstanding Class
B shares.

John S. Richardson, 100 Peachtree Way, Atlanta, GA  30305-3738, owned 7% of such
Portfolio's total outstanding Class B shares.

Caroline B. Case, 54 Tanglewylde Avenue, Bronxville, NY  10708, owned 7% of such
Portfolio's total outstanding Class B shares.

Peter Boer, 47 Country Road, Village of Golf, FL  33436-5604, owned 7% of such
Portfolio's total outstanding Class B shares.

Mr. James Fuld, Jr., 114 East 72nd Street, New York, NY  10021, owned 6% of such
Portfolio's total outstanding Class B shares.

Walter Kaye, 475 Park Avenue, new York, NY  10022-1902, owned 5% of such
Portfolio's total outstanding Class B shares.

ASIAN EQUITY PORTFOLIO:  Association De Bienfaisance Et De Retraite Des
Policiers De La Communaute Urbaine De Montreal, 480 Gilford Street, Montreal,
Quebec H2J1N3, owned 8% of such Portfolio's total outstanding Class A shares.

Northern Trust Company Trustee, FBO Morgan Stanley Profit Sharing Plan, P.O.Box
92956, Chicago, IL 60675-2956, owned 5% of such Portfolio's total outstanding
Class A shares.

BALANCED PORTFOLIO:  The American Roentgen Ray Society, 1891 Preston White
Drive, Reston, VA 22091-5431, owned 27% of such Portfolio's total outstanding
Class A shares.

William Guthrie, IRA Rollover, 435 Sheridan Road, Winnetka, IL  60093-2626,
owned 16% of such Portfolio's total outstanding Class B shares.

EMERGING GROWTH PORTFOLIO:  Northern Trust Company Trustee, FBO Morgan Stanley
Profit Sharing Plan, P.O. Box 92956, Chicago, IL 60675-2956, owned 26% of such
Portfolio's total outstanding Class A shares.

Allendale Mutual Insurance Co., P.O. Box 7500, Johnston, RI 02919-0750, owned
10% of such Portfolio's total outstanding Class A shares.

Mac & Co. A/C Benf 0741602, P.O. Box 3198, Pittsburgh, PA 15230, owned 8% of
such Portfolio's total outstanding Class A shares.

EMERGING MARKETS DEBT PORTFOLIO:  Northwestern University, 633 Clark Street,
Evanston, IL 60208-1122, owned 13% of such Portfolio's total outstanding Class A
shares.

Swarthmore College, 500 College Avenue, Swarthmore, PA 19081-1110, owned 7% of
such Portfolio's total outstanding Class A shares.

Eleanor S. Herkert, Trustee of the Eleanor S. Herkert Trust, 2000 Diana Drive
Apt. 101, Lakeview West, Hallandale, FL  33009-4709, owned 6% of such
Portfolio's total outstanding Class B shares.

    

                                          29

<PAGE>

   

Donald A. Moore, Jr., 160 E. 42 Street, New York, NY  10021, owned 5% of such
Portfolio's total outstanding Class B shares.

Delaware Charter Guarantee & Trust Company, IRA Rollover, 15 Garden Place,
Brooklyn, NY  11204-4581, owned 5% of such Portfolio's total outstanding Class B
shares.

Paul and Lauren Ghaffari, 49 Grosset Road, Riverside, CT  06878, owned 5% of
such Portfolio's total outstanding Class B shares.

David Brooks Gendron, c/o CS First Boston - London, 55 East 52nd Street, New
York, NY  10055, owned 5% of such Portfolio's total outstanding Class B shares.


EMERGING MARKETS PORTFOLIO:  Ministers & Missionaries Benefit Board of the
American Baptist Churches, 475 Riverside Drive, New York, NY 10115, owned 10% of
such Portfolio's total outstanding Class A shares.

Ewing Marion Kauffman Foundation, 4900 Oak Street, Kansas City, MO 64112, owned
8% of such Portfolio's total outstanding Class A shares.

EQUITY GROWTH PORTFOLIO:  Northern Trust Company Trustee, FBO Morgan Stanley
Profit Sharing Plan, P.O. Box 92956, Chicago, IL 60675, owned 35% of such
Portfolio's total outstanding Class A shares.

Donald A. Moore Jr., 160 E. 42 Street, New York, NY  10021, owned 8% of such
Portfolio's total outstanding Class B shares.

EUROPEAN EQUITY PORTFOLIO:  James P. Smith Jr., 552 Ponte Vedra Boulevard, Ponte
Vedra, FL  32082-2316, owned 10% of such Portfolio's total outstanding Class B
shares.

Beatrice Synder, Trustee FBO Jay Synder 21484, 300 Winston Drive Apt. 1711,
Cliff Side Park, NJ  07010-3222, owned 10% of such Portfolio's total outstanding
Class B shares.

Deborah Meredith, 1386 Pritchett Court, Los Altos, CA  94024-5713, owned 10% of
such Portfolio's total outstanding Class B shares.

Steven J. Wong, 20021 Marribrook Drive, Saratoga, CA  95070-5445, owned 10% of
such Portfolio's total outstanding Class B shares.

Benedikt Von Schroder & Kristin Von Schroder, Burnitz str. 67, 6000 Frankfurt 
70, Germany, owned 9% of such Portfolio's total outstanding Class B shares.

FIXED INCOME PORTFOLIO:  Northern Trust Company Trustee, FBO Morgan Stanley
Profit Sharing Plan, P.O. Box 92956, Chicago, IL 60675-2956, owned 22% of such
Portfolio's total outstanding Class A shares.

Brooks School, c/o Mr. Frank Marino, North Andover, MA 01845, owned 6% of such
Portfolio's total outstanding Class A shares.

Morgan Stanley Foundation, 1221 Avenue of the Americas, New York, NY 10020,
owned 5% of such Portfolio's total outstanding Class A shares.

John B. & Judy D. Morel, 28 Twelve Pines, The Woodlands, TX  77381, owned 9% of
such Portfolio's total outstanding Class B shares.

William M. Manger, Jr., 8 E. 81 Street, New York, NY  10028-0201, owned 5% of
such Portfolio's total outstanding Class B shares.

Harold J. Schaaff, IRA, 49 Old Orchard Lane, Ocean TWP, NJ  07712, owned 5% of
such Portfolio's total outstanding Class B shares.

Delaware Charter & Guarantee & Trust, IRA Rollover, 5813 East North Avenue,
Kalamazoo, MI  49009, owned 5% of such Portfolio's total outstanding Class B
shares.

Michael J. and Patricia L. Berchtold, Morgan Stanley, 1251 Avenue of the
Americas, Hong Kong Pouch, New York, NY  10020-1104, owned 5% of such
Portfolio's total outstanding Class B shares.

    

                                          30

<PAGE>

   

GLOBAL EQUITY PORTFOLIO:  Robert College of Istanbul Turkey C/O Morgan Stanley
Asset Management, 25 Cabot Square, London, England E144QA, owned 49% of such
Portfolio's total outstanding Class A shares.

Gaz Metropolitan and Company Limited Partnership, 1717 Du Havre, Montreal,
Canada H2K-2X3, owned 15% of such Portfolio's total outstanding Class A shares.

JM Kaplan Fund, Inc., 880 Third Avenue 3rd floor, New York, NY 10022, owned 13%
of such Portfolio's total outstanding Class A shares.

Divtex and Company FBO, Pritchard Hubble and Herr C/O Texas Commerce Bank, P.O.
Box 951405, Dallas, TX 75395, owned 9% of such Portfolio's total outstanding
Class A shares.

North American Trust Company, FBO Heller/Robert S. Venning, P.O. Box 84419, San
Diego, CA  92138, owned 13% of such Portfolio's total outstanding Class B
shares.

Douglas E. Ebert Trust, Douglas E. Ebert, Trustee and Successor in Trust, 3470
Twin Oaks Court, W. Bloomfield, MI  48324-3249, owned 7% of such Portfolio's
total outstanding Class B shares.

John F. Raynolds III, 386 Park Avenue, South 18th Floor, New York, NY  10016,
owned 6% of such Portfolio's total outstanding Class B shares.

GLOBAL FIXED INCOME PORTFOLIO:  Farm Credit Bank Retirement Plan, Columbia
District American Industries Trust Company Trustee, 5700 NW Central Drive, 4th
Floor, Houston, TX 77092, owned 15% of such Portfolio's total outstanding Class
A shares.

Northern Trust Company as Custodian FBO The Lund Foundation, P.O. Box 92956,
Chicago, IL 60675, owned 11% of such Portfolio's total outstanding Class A
shares.

The Northern Trust Customer FBO Resort Condominiums International, P.O. Box
92956, Chicago, IL 60675-2956, owned 7% of such Portfolio's total outstanding
Class A shares.

Divtex and Co., FBO Pritchard Hubble and Herr, c/o Texas Commerce Bank, P.O. Box
951405, Dallas, TX 75395-1405, owned 6% of such Portfolio's total outstanding
Class A shares.

David Brooks Gendron, C/O CS First Boston - London, 55 East 52nd Street, New
York, NY  10055, owned 11% of such Portfolio's total outstanding Class B shares.

Marjorie S. Burggraf, FBO The Robert V. Burgraff Family Trust UTA DTD 11-5-86,
2378 E. Oakmont Drive, Idaho Falls, ID  83404-7720, owned 8% of such Portfolio's
total outstanding Class B shares.

Harold L. Tailisman, 837 New Hampshire Avenue, Washington, DC  20037-2305, owned
6% of such Portfolio's total outstanding Class B shares.

Steven J. Wong, 20021 Marribrook Drive, Saratoga, CA  95070-5445, owned 5% of
such Portfolio's total outstanding Class B shares.

Alexander P. Hixon Jr., Anthony Hixon & Andrew R. Hixon Trustees FBO Hixon
Family Char. Remainder, 70 S. Lake Avenue STE 1075, Pasadena, CA  91101-2206,
owned 5% of such Portfolio's total outstanding Class B shares.

Thomas E. Congden, 1776 Lincoln Street, Suite 1100, Denver, CO  80203-1080,
owned 5% of such Portfolio's total outstanding Class B shares.

GOLD PORTFOLIO:  Stockton Trust Partnership, 7373 North Scottsdale Road,
Scottsdale, AZ 85253, owned 49% of such Portfolio's total outstanding Class A
shares.

Judith L. Biggs, 390 Riversville Road, Greenwich, CT 06831-3200, owned 12% of
such Portfolio's total outstanding Class A shares.


Charlotte Beers, Ogilvy & Mather, 309 West 49th Street, New York, NY 10019-7316,
owned 7% of such Portfolio's total outstanding Class A shares.

    

                                          31

<PAGE>

   

Trust U/A Sixth Will of Howard Ross, C/O James H. Ross, Rossrock Company, Inc.,
150 East 52nd Street, New York, NY 10020, owned 5% of such Portfolio's total
outstanding Class A shares.

Kinghugh S.A., c/o Office of Directors, Chin Lan Building, 306 Tun Hwa Road,
South Taipei, owned 5% of such Portfolio's total outstanding Class A shares.

Sunil T. Wadhwani, 930 Osage Road, Pittsburgh, PA  15243, owned 47% of such
Portfolio's total outstanding Class B shares.

Gregory W. Neumann, 5 Mt. Austin Road, House B, The Peak, Hong Kong, owned 20%
of such Portfolio's total outstanding Class B shares.

Michael J. and Patricia L. Berchtold, Morgan Stanley, 1251 Avenue of the
Americas, Hong Kong Pouch, New York, NY  10020-1104, owned 10% of such
Portfolio's total outstanding Class B shares.

Matthew and Deborah Carrara, 443 W. Eugnie Street, Apt. 3E, Chicago, IL  60614,
owned 8% of such Portfolio's total outstanding Class B shares.

Christian B. Malone, 750 Columbus Avenue, Apt. 8N, New York, NY  10025-6479,
owned 7% of such Portfolio's total outstanding Class B shares.

HIGH YIELD PORTFOLIO:  Northern Trust Company Trustee, FBO Morgan Stanley Profit
Sharing Plan, P.O. Box 92956, Chicago, IL 60675-2956, owned 28% of such
Portfolio's total outstanding Class A shares.

Valassis Enterprises - Equity, c/o Franklin Enterprises, 520 Lake Cook Road,
Suite 380, Deerfield, IL 60015, owned 19% of such Portfolio's total outstanding
Class A shares.

Morgan Stanley & Co. Pension Fund, c/o Northern Trust Company, 770 Broadway, New
York, NY 10003, owned 6% of such Portfolio's total outstanding Class A shares.

Austin Koenen, 360 Sunset Road, Pompton Plains, NJ  07444-1513, owned 15% of
such Portfolio's total outstanding Class B shares.

Arthur H. and Julia E. Maurer, 5349 Cedar Lake Road Apt. 12-33, Boynton Beach,
FL  33437-3046, owned 7% of such Portfolio's total outstanding Class B shares.

Eleanor S. Herkert, Trustee of the Eleanor S. Herkert Trust, 2000 Diana Drive,
Apt. 101, Hallandale, FL  33009-4709, owned 7% of such Portfolio's total
outstanding Class B shares.

David J. Barrett, 320 E. 46th Street, Apt. 18-H, New York, NY  10017, owned 5%
of such Portfolio's total outstanding Class B shares.

INTERNATIONAL MAGNUM PORTFOLIO:  Ameritas Life Insurance Corporation, P.O. Box
81889, Lincoln, NE  68501, owned 57% of such Portfolio's total outstanding Class
A shares.

Luanne C. Wells and Paul C. Heeschen Trustees, FBO Palm Trust, 450 Newport
Center Drive, Newport Beach, CA  92660-7614, owned 43% of such Portfolio's total
outstanding Class A shares.

The Chase Manhattan Bank, NA, Custodian for the IRA of Toni Villasenor Brown,
335 Emerty Drive East, Stamford, CT  06902, owned 50% of such Portfolio's total
outstanding Class B shares.

The Chase Manhattan Bank, NA, Custodian for the IRA of Jeffrey Paul Brown, 335
Emery Drive East, Stamford, CT  06902, owned 50% of such Portfolio's total
outstanding Class B shares.

INTERNATIONAL SMALL CAP PORTFOLIO:  The Short Brothers Pension Fund, P.O. Box
241, Airport Road, Belfast, N. Ireland, owned 11% of such Portfolio's total
outstanding Class A shares.

The Casey Family Program, 1300 Dexter Avenue, Suite 400, Seattle, WA 98109-3547,
owned 8% of such Portfolio's total outstanding Class A shares.

    

                                          32

<PAGE>

   

Trustees of Boston College Attn:  Paul Haran Associates Treasurer, St. Thomas
More Hall 310, Chestnut Hill, MA 02167, owned 7% of such Portfolio's total
outstanding Class A shares.

General Mills, Inc. Master Trust:  Pooled International Fund, One General Mills
Blvd., Minneapolis, MN 55426, owned 7% of such Portfolio's total outstanding
Class A shares.

JAPANESE EQUITY PORTFOLIO:  Sunil T. Wadhwani, 930 Osage Road, Pittsburgh, PA
15243, owned 7% of such Portfolio's total outstanding Class B shares.

William H. Davidow, 85 Robles Drive, Woodside, CA  94062-2204, owned 6% of such
Portfolio's total outstanding Class B shares.

Eric Dunn, Investment Account, 1470 Arcadia Place, Palo Alto, CA  94303, owned 
6% of such Portfolio's total outstanding Class B shares.

LATIN AMERICAN PORTFOLIO:  Chicago Methodist Episcopal Church Aid Society, C/O
Gordon Worley, 4401 Gulf Shore Boulevard, Naples, FL  33940, owned 29% of such
Portfolio's total outstanding Class B shares.

Henri Dyner, 232 Truman Drive, Cresskill, NJ  07626, owned 29% of such
Portfolio's total outstanding Class B shares.

John P. Hanlon and Janet K. Hanlon, 7 Stafford Place, Towaco, NJ  07082, owned
10% of such Portfolio's total outstanding Class B shares.

Lawrence B. Sorrel, 58 Taunton Road, Scarsdale, NY  10583, owned 8% of such
Portfolio's total outstanding Class B shares.

MUNICIPAL BOND PORTFOLIO:  Daniel F. McDonald and Maria J. McDonald, 8550 Old
Dominion Drive, McLean, VA 22102, owned 11% of such Portfolio's total
outstanding Class A shares.

Cushman Trust, C/O Cambrian Services, 1114 Avenue of the Americas, Suite 2702,
New York, NY  10036, owned 5% of such Portfolio's total outstanding Class A
shares.

Arnold E. Bellowe and Jill I. Bellowe Trustees, 915 Park Lane, Montecito, CA
93108-1421, owned 5% of such Portfolio's total outstanding Class A shares.

James A. Rutherford, C/O Wingset Inc., 15 South High Street, P.O. Box 166, New
Albany, OH 43054-0166, owned 5% of such Portfolio's total outstanding Class A
shares.

James W. Grisham and Diana E. Grisham, 454 South Pleasant Avenue, Ridgewood, NJ
07450-5446, owned 100% of such Portfolio's total outstanding Class B shares.

SMALL CAP VALUE EQUITY PORTFOLIO:  Morgan Stanley & Co. Pension Fund, c/o
Northern Trust Company, 770 Broadway Street, New York, NY 10003, owned 12% of
such Portfolio's total outstanding Class A shares.

Kinney Printing Co-Employees, Attn:  Dolores M. Miklos, 4801 South Lawndale,
Chicago, IL 60632-3018, owned 92% of such Portfolio's total outstanding Class B
shares.

George W. Gardner, Self Declaration of Trust, 70 E. Cedar, Chicago, IL  60611,
owned 7% of such Portfolio's total outstanding Class B shares.

Frank E. Hunt Trust, 8627 Madison Drive, Niles, IL  60648-2321, owned 6% of such
Portfolio's total outstanding Class B shares.

Michael E. Dee, C/O Morgan Stanley Mailroom, 1585 Broadway, New York, NY
10036-8293, owned 6% of such Portfolio's total outstanding Class B shares.

U.S. REAL ESTATE PORTFOLIO:  European Patent Organization Pension Reserve Fund,
Erhardtstrasse 27, Munich, Germany 80331, owned 7% of such Portfolio's total
outstanding Class A shares.

    

                                          33

<PAGE>

   

Morgan, Stanley & Co. Pension Fund, C/O Northern Trust Company, 770 Broadway,
New York, NY  10003, owned 10% of such Portfolio's total outstanding Class A
shares.

Eleanor S. Herkert, Trustee of The Eleanor S. Herkert Trust, 2000 Diana Drive,
Lakeview West, Hallandale, FL  33009-4709, owned 10% of such Portfolio's total
outstanding Class B shares.

Kansas Children's Service League, P.O. Box 517, Wichita, KS  67201, owned 8% of
such Portfolio's total outstanding Class B shares.

Donald A. Moore, Jr., 160 E. 72 Street, New York, NY  10021, owned 8%  of such
Portfolio's total outstanding Class B shares.

VALUE EQUITY PORTFOLIO:  Northern Trust Company Trustee, FBO Morgan Stanley
Profit Sharing Plan, P.O. Box 92956, Chicago, IL 60675, owned 17% of such
Portfolio's total outstanding Class A shares.

Victoria B. McLaughlin, Upper Dogwood Lane, Rye, NY  10580, owned 8% of such
Portfolio's total outstanding Class B shares.

Delaware Charter Guarantee & Trust Company, C/F Nelaura O. Lewis, IRA Rollover,
78 Cedar Cliff Road, Riverside, CT  06878, owned 5% of such Portfolio's total
outstanding Class B shares.

    

                     NET ASSET VALUE FOR MONEY MARKET PORTFOLIOS

       The Money Market Portfolio and the Municipal Money Market Portfolio seek
to maintain a stable net asset value per share of $1.00.  These Portfolios use
the amortized cost method of valuing their securities, which does not take into
account unrealized gains or losses.  The use of amortized cost and the
maintenance of each Portfolio's per share net asset value at $1.00 is based on
the Portfolio's election to operate under the provisions of Rule 2a-7 under the
1940 Act.  As a condition of operating under that Rule, each of the Money Market
Portfolios must maintain a dollar-weighted average portfolio maturity of 90 days
or less, purchase only instruments having remaining maturities of 397 days or
less, and invest only in securities which are of "eligible quality" as
determined in accordance with regulations of the Commission.

       The Rule also requires that the Directors, as a particular
responsibility within the overall duty of care owed to shareholders, establish
procedures reasonably designed, taking into account current market conditions
and each Portfolio's investment objectives, to stabilize the net asset value per
share as computed for the purposes of sales and redemptions at $1.00. These
procedures include periodic review, as the Directors deem appropriate and at
such intervals as are reasonable in light of current market conditions, of the
relationship between the amortized cost value per share and a net asset value
per share based upon available indications of market value.  In such review,
investments for which market quotations are readily available are valued at the
most recent bid price or quoted yield available for such securities or for
securities of comparable maturity, quality and type as obtained from one or more
of the major market makers for the securities to be valued.  Other investments
and assets are valued at fair value, as determined in good faith by the
Directors.

       In the event of a deviation of over 1/2 of 1% between a Portfolio's net
asset value based upon available market quotations or market equivalents and
$1.00 per share based on amortized cost, the Directors will promptly consider
what action, if any, should be taken.  The Directors will also take such action
as they deem appropriate to eliminate or to reduce to the extent reasonably
practicable any material dilution or other unfair results which might arise from
differences between the two.  Such action may include redemption in kind,
selling instruments prior to maturity to realize capital gains or losses or to
shorten the average maturity, withholding dividends, paying distributions from
capital or capital gains or utilizing a net asset value per share as determined
by using available market quotations.

       There are various methods of valuing the assets and of paying dividends
and distributions from a money market fund.  Each of the Money Market and
Municipal Money Market Portfolios values its assets at amortized cost while also
monitoring the available market bid price, or yield equivalents.  Since
dividends from net investment income will be declared daily and paid monthly,
the net asset value per share of each Portfolio will ordinarily remain at $1.00,
but each Portfolio's daily dividends will vary in amount.  Net realized gains,
if any, will normally be declared and paid monthly.


                                          34

<PAGE>

                               PERFORMANCE INFORMATION

       The Fund may from time to time quote various performance figures to
illustrate the Portfolios' past performance.

       Performance quotations by investment companies are subject to rules
adopted by the Commission, which require the use of standardized performance
quotations.  In the case of total return, non-standardized performance
quotations may be furnished by the Fund but must be accompanied by certain
standardized performance information computed as required by the Commission.
Current yield and average annual compounded total return quotations used by the
Fund are based on the standardized methods of computing performance mandated by
the Commission.  An explanation of those and other methods used by the Fund to
compute or express performance follows.

TOTAL RETURN

   
       From time to time each Portfolio, except the Money Market and Municipal
Money Market Portfolios, may advertise total return for each class of shares of
the Portfolio.  Total return figures are based on historical earnings and are
not intended to indicate future performance.  The average annual total return is
determined by finding the average annual compounded rates of return over 1-, 5-,
and 10-year periods (or over the life of the Portfolio) that would equate an
initial hypothetical $1,000 investment to its ending redeemable value.  The
calculation assumes that all dividends and distributions are reinvested when
paid.  The quotation assumes the amount was completely redeemed at the end of
each 1-, 5-, and 10-year period (or over the life of the Portfolio) and the
deduction of all applicable Fund expenses on an annual basis.

       The average annual compounded rates of return (unless otherwise noted)
for the Fund's Portfolios for the one year and five year periods ended December
31, 1995 and for the period from inception through December 31, 1995 are as
follows:

<TABLE>
<CAPTION>

          Name of Portfolio                                        Since Date
         and Date of Inception           One Year     Five Year   of Inception
         ---------------------           --------     ---------   ------------
         <S>                             <C>          <C>         <C>
         International Equity
         August 4, 1989. . . . . . . .     11.77%        14.24%         10.82%

         Emerging Growth
         November 1, 1989. . . . . . .     33.31         14.48          13.36

         Value Equity
         January 31, 1990. . . . . . .     33.69         15.65          11.86

         Balanced
         February 28, 1990 . . . . . .     23.63         11.45          10.31

         Equity Growth
         April 2, 1991 . . . . . . . .     45.02           N/A          14.33

<CAPTION>

          Name of Portfolio                                        Since Date
         and Date of Inception           One Year     Five Year   of Inception
         ---------------------           --------     ---------   ------------
         <S>                             <C>          <C>         <C>
         Global Fixed Income
         May 1, 1991 . . . . . . . . .     19.32           N/A           8.95

         Fixed Income
         May 15, 1991. . . . . . . . .     18.76           N/A           9.18

         Asian Equity
         July 1, 1991. . . . . . . . .      6.87           N/A          21.85



                                          35

<PAGE>


Active Country Allocation

<CAPTION>
         <S>                               <C>             <C>           <C>
         January 17, 1992. . . . . . .     10.57           N/A           8.46

         Global Equity
         July 15, 1992 . . . . . . . .     18.66           N/A          18.21

         Emerging Markets
         September 25, 1992. . . . . .    (12.77)          N/A          13.16

         High Yield
         September 28, 1992. . . . . .     23.35           N/A          12.28

         International Small Cap
         December 15, 1992 . . . . . .      2.60           N/A          16.30

         Small Cap Value Equity
         December 17, 1992 . . . . . .     20.63           N/A          11.61

         European Equity
         April 2, 1993 . . . . . . . .     11.85           N/A          18.68

         Emerging Markets Debt
         February 1, 1994. . . . . . .     28.23           N/A           5.18

         Gold
         February 1, 1994. . . . . . .     13.21           N/A           1.87

         Japanese Equity
         April 25, 1994. . . . . . . .     (3.64)          N/A          (3.17)

         Latin American
         January 18, 1995. . . . . . .    N/A              N/A          (8.68)

         Municipal Bond
         January 18, 1995. . . . . . .    N/A              N/A           8.80

         U.S. Real Estate
         February 24, 1995 . . . . . .    N/A              N/A          21.07

         Aggressive Equity
         March 8, 1995 . . . . . . . .    N/A              N/A          41.25

         International Magnum
         March 15, 1996. . . . . . . .    N/A              N/A        N/A
</TABLE>

    

These figures were calculated according to the following formula: 
             P(1 + T)to the nth power = ERV

where:

P      =      a hypothetical initial payment of $1,000

T      =      average annual total return

n      =      number of years


                                          36

<PAGE>

ERV     =     ending redeemable value of hypothetical $1,000 payment made at
              the beginning of the 1-, 5-, or 10-year periods at the end of
              the 1-, 5-, or 10-year periods (or fractional portion thereof).

CALCULATION OF YIELD FOR NON-MONEY MARKET PORTFOLIOS

       From time to time certain of the Fund's Portfolios may advertise yield.

       Current yield reflects the income per share earned by a Portfolio's
investments.

       Current yield is determined by dividing the net investment income per
share earned during a 30-day base period by the maximum offering price per share
on the last day of the period and annualizing the result.  Expenses accrued for
the period include any fees charged to all shareholders during the base period.

   
       The respective yields for certain of the Fund's Portfolios for the
30-day period ended December 31, 1995 were as follows:

<TABLE>
<CAPTION>

                   PORTFOLIO NAME                       30-DAY YIELD
                   --------------                       ------------
                   <S>                                  <C>

                   Emerging Markets Debt . . . . . . .    15.67%

                   Fixed Income. . . . . . . . . . . .     6.39%

                   Global Fixed Income . . . . . . . .     5.91%

                   High Yield. . . . . . . . . . . . .    10.65%

                   Municipal Bond. . . . . . . . . . .     4.17%
</TABLE>
    

       These figures were obtained using the following formula:

                   Yield = 2[( a -  b + 1 )to the 6th power  - 1]
                               ------
                                 cd

       where:

       a      =    dividends and interest earned during the period
       b      =    expenses accrued for the period (net of reimbursements)
       c      =    the average daily number of shares outstanding during the
                   period that were entitled to receive income distributions
       d      =    the maximum offering price per share on the last day of the
                   period.


CALCULATION OF YIELD FOR MONEY MARKET PORTFOLIOS

   

       The current yield of the Money Market and Municipal Money Market
Portfolios is calculated daily on a base period return for a hypothetical
account having a beginning balance of one share for a particular period of time
(generally 7 days).  The return is determined by dividing the net change
(exclusive of any capital changes in such account) by its average net asset
value for the period, and then multiplying it by 365/7 to determine the
annualized current yield.  The calculation of net change reflects the value of
additional shares purchased with the dividends by the Portfolio, including
dividends on both the original share and on such additional shares.  The yields
of the Money Market and Municipal Money Market Portfolios for the 7-day period
ended Decmber 31, 1995 were 5.21% and 3.91%, respectively.  An effective yield,
which reflects the effects of compounding and represents an annualization of the
current yield with all dividends reinvested, may also be calculated for each
Portfolio by dividing the base period return by 7, adding 1 to the quotient,
raising the sum to the 365th power, and subtracting 1 from the result.  The
effective yields of the Money Market and Municipal Money Market Portfolios for
the 7-day period ended December 31, 1995 were 5.34% and 3.99%, respectively.

    

                                          37

<PAGE>


       The yield of a Portfolio will fluctuate.  The annualization of a week's
dividend is not a representation by the Portfolio as to what an investment in
the Portfolio will actually yield in the future.  Actual yields will depend on
such variables as investment quality, average maturity, the type of instruments
the Portfolio invests in, changes in interest rates on instruments, changes in
the expenses of the Fund and other factors.  Yields are one basis investors may
use to analyze the Portfolios of the Fund, and other investment vehicles;
however, yields of other investment vehicles may not be comparable because of
the factors set forth in the preceding sentence, differences in the time periods
compared, and differences in the methods used in valuing portfolio instruments,
computing net asset value and calculating yield.

TAXABLE EQUIVALENT YIELD FOR THE MUNICIPAL BOND AND MUNICIPAL MONEY MARKET
PORTFOLIO

       It is easy to calculate your own taxable equivalent yield if you know
your tax bracket.  The formula is:

                Tax Free Yield
              --------------------
              1 - Your Tax Bracket    =    Your Taxable Equivalent Yield

       For example, if you are in the 28% tax bracket and can earn a tax-free
yield of 7.5%, the taxable equivalent yield would be 10.42%.

   
        The table below indicates the advantages of investments in Municipal
Bonds for certain investors.  Tax-exempt rates of interest payable on a
Municipal Bond (shown at the top of each column) are equivalent to the taxable
yields set forth opposite the respective income tax levels, based on income tax
rates effective for the tax year 1995 under the Internal Revenue Code.  There
can, of course, be no guarantee that the Municipal Bond Portfolio or Municipal
Money Market Portfolio will achieve a specific yield.  Also, it is possible that
some portion of the Portfolio's dividends may be subject to Federal income
taxes. A substantial portion, if not all, of such dividends may be subject to
state and local taxes.
    

TAXABLE EQUIVALENT YIELD TABLE

<TABLE>
<CAPTION>

        Sample Level of                                                             Taxable Equivalent Rates
        Taxable Income                                                            Based on Tax-Exempt Yield of:
        --------------                                                            -----------------------------
                                   Federal
                                   Income
Joint            Single            Tax
Return           Return            Bracket  3%       4%        5%        6%        7%        8%        9%        10%        11%
- ------           ------            -------  --       --        --        --        --        --        --        ---        ---
 
<S>              <C>               <C>      <C>      <C>       <C>       <C>       <C>       <C>       <C>       <C>        <C>
$0-39,000        $0-23,350         15.0%    3.5%     4.7%      5.9%      7.1%       8.2%      9.4%     10.6%     11.8%      12.9%
39,000-94,250    23,350-56,550     28.0     4.2      5.6       6.9       8.3        9.7      11.1      12.5      13.9       15.3
94,250-143,600   56,550-117,950    31.0     4.3      5.8       7.2       8.7       10.1      11.6      13.0      14.5       15.9
143,600-256,500  117,950-256,500   36.0     4.7      6.3       7.8       9.4       10.9      12.5      14.1      15.6       17.2
over 256,500     over 256,500      39.6     5.0      6.6       8.3       9.9       11.6      13.2      14.9      16.6       18.2
</TABLE>

- -------

   
*      Net amount subject to 1995 Federal Income Tax after deductions and
       exemptions, not indexed for 1995 income tax rates.

The taxable equivalent yields for the Municipal Money Market and Municipal Bond
Portfolios for the seven days ended December 31, 1995 assuming a Federal income
tax rate of 39.6% (maximum rate), were 6.47% and 7.86%, respectively.  The
taxable equivalent effective yields for the Municipal Money Market and Municipal
Bond Portfolios for the seven days ended December 31, 1995, assuming the same
tax rate, were 6.61% and 8.05%, respectively.
    

COMPARISONS

       To help investors better evaluate how an investment in a Portfolio of
Morgan Stanley Institutional Fund, Inc. might satisfy their investment
objective, advertisements regarding the Fund may discuss various measures of
Fund performance as reported by various financial publications.  Advertisements
may also compare performance (as calculated above) to performance as reported by
other investments, indices and averages.  The following publications may be
used:

         (a)  CDA Mutual Fund Report, published by CDA Investment Technologies,
              Inc. -- analyzes price, current yield, risk, total return and
              average rate of return (average annual compounded growth rate)
              over specified time periods for the mutual fund industry.

                                          38

<PAGE>

         (b)  Financial publications:  Business Week, Changing Times, Financial
              World, Forbes, Fortune, Money, Barron's, Consumer's Digest,
              Financial Times, Global Investor, Investor's Daily, Lipper
              Analytical Services, Inc., Morningstar, Inc., New York Times,
              Personal Investor, Wall Street Journal and Weisenberger
              Investment Companies Service -- publications that rate fund
              performance over specified time periods.

         (c)  Historical data supplied by the research departments of First
              Boston Corporation, the J.P. Morgan companies, Salomon Brothers,
              Merrill Lynch, Pierce, Fenner & Smith, Lehman Brothers and
              Bloomberg L.P.

         (d)  Lipper -- Mutual Fund Performance Analysis and Lipper -- Fixed
              Income Fund Performance Analysis -- measures total return and
              average current yield for the mutual fund industry.  Ranks
              individual mutual fund performance over specified time periods,
              assuming reinvestment of all distributions, exclusive of any
              applicable sales charges.

         (e)  Mutual Fund Source Book, published by Morningstar, Inc. --
              analyzes price, yield, risk and total return for equity funds.

   

         (f)  Savings and Loan Historical Interest Rates -- as published in the
              U.S. Savings & Loan League Fact Book.

         (g)  Stocks, Bonds, Bills and Inflation, published by Hobson
              Associates -- historical measure of yield, price and total return
              for common and small company stock, long-term government bonds,
              U.S. Treasury bills and inflation.

The following indices and averages may also be used:

         (a)  Composite Indices -- 70% Standard & Poor's 500 Stock Index and
              30% NASDAQ Industrial Index; 35% Standard & Poor's 500 Stock
              Index and 65% Salomon Brothers High Grade Bond Index; and 65%
              Standard & Poor's 500 Stock Index and 35% Salomon Brothers High
              Grade Bond Index.

         (b)  Consumer Price Index (or cost of Living Index), published by the
              U.S. Bureau of Labor Statistics -- a statistical measure of
              change, over time, in the price of goods and services in major
              expenditure groups.

         (c)  Donoghue's Money Fund Average -- an average of all major money
              market fund yields, published weekly for 7 and 30-day yields.

         (d)  Dow Jones Composite Average or its component averages -- an
              unmanaged index composed of 30 blue-chip industrial corporation
              stocks (Dow Jones Industrial Average), 15 utilities company
              stocks and 20 transportation stocks.  Comparisons of performance
              assume reinvestment of dividends.

         (e)  EMBI+ -- Expanding on the EMBI, which includes only Bradys, the
              EMBI+ includes a broader group of Brady Bonds, loans, Eurobonds
              and the U.S. Dollar local markets instruments.  A more
              comprehensive benchmark than the EMBI, the EMBI+ covers 49
              instruments from 14 countries.  At $96 billion, its market cap is
              nearly 50% higher than the EMBI's.  The EMBI+ is not, however,
              intended to replace the EMBI but rather to complement it.  The
              EMBI continues to represent the most liquid, most easily traded
              segment of the market, including more of the assets that
              investors typically hold in their portfolios.  Both of these
              indices are published daily.

         (f)  First Boston High Yield Index -- generally includes over 180
              issues with an average maturity range of seven to ten years with
              a minimum capitalization of $100 million.  All issues are
              individually trader-priced monthly.

         (g)  First Boston Upper/Middle Tier High Yield Index -- an unmanaged
              index of bonds rated B to BBB.

         (h)  Goldman Sachs 100 Convertible Bond Index -- currently includes 67
              bonds and 33 preferred.  The original list of names was generated
              by screening for convertible issues of 100 million or greater in
              market capitalization.  The index is priced monthly.

         (i)  IFC Global Total Return Composite Index -- an unmanaged index of
              common stocks and includes 18 developing countries in Latin
              America, East and South Asia, Europe, the Middle East and Africa
              (net of dividends reinvested).

    

                                          39

<PAGE>

   

         (j)  Indata Balanced-Median Index -- an unmanaged index and includes
              an asset allocation of 7% cash, 39% bonds and 54% equity based on
              $37.8 billion in assets among 538 portfolios for the year ended
              December 31, 1995 (assumes dividends reinvested).

         (k)  Indata Equity-Median Stock Index -- an unmanaged index which
              includes an average asset allocation of 5% cash and 95% equity
              based on $30.6 billion in assets among 562 portfolios for the
              year ended December 31, 1995.

         (l)  J.P. Morgan Emerging Markets Bond Index -- a market-weighted
              index composed of all Brady bonds outstanding and includes
              Argentina, Brazil, Bulgaria, Mexico, Nigeria, the Philippines,
              Poland and Venezuela.

         (m)  J.P. Morgan Traded Global Bond Index -- an unmanaged index of
              securities and includes Australia, Belgium, Canada, Denmark,
              France, Germany, Italy, Japan, The Netherlands, Spain, Sweden,
              United Kingdom and the United States.

         (n)  Lehman Brothers Aggregate Bond Index -- an unmanaged index made
              up of the Government/Corporate Index, the Mortgage Backed
              Securities Index and the Asset-Backed Securities Index.

         (o)  Lehman Brothers LONG-TERM Treasury Bond -- composed of all bonds
              covered by the Lehman Brothers Treasury Bond Index with
              maturities of 10 years or greater.

         (p)  The Lehman 7 Year Municipal Bond Index -- an unmanaged index
              which consists of investment grade bonds with maturities between
              6-8 years rated BAA or better.  All bonds have been taken from
              deals done within the last 5 years, with assets of $50 million or
              larger.

         (q)  Lipper Capital Appreciation Index -- a composite of mutual funds
              managed for maximum capital gains.

         (r)  Morgan Stanley Capital International Combined Far East Free
              ex-Japan Index -- a market-capitalization weighted index
              comprising stocks in Hong Kong, Indonesia, Korea, Malaysia,
              Philippines, Singapore, Taiwan and Thailand.  Korea is included
              in the MSCI Combined Far East Free ex-Japan Index at 20% of its
              market capitalization.

         (s)  Morgan Stanley Capital International EAFE Index -- an arithmetic,
              market value-weighted average of the performance of over 900
              securities on the stock exchanges of countries in Europe,
              Australia and the Far East.

         (t)  Morgan Stanley Capital International Emerging Markets Global
              Latin American Index -- an unmanaged, arithmetic market value
              weighted average of the performance of over 196 securities on the
              stock exchanges of Argentina, Brazil, Chile, Colombia, Mexico,
              Peru and Venezuela (Assumes reinvestment of dividends).

         (u)  Morgan Stanley Capital International Europe Index -- an unmanaged
              index of common stocks and includes 14 countries throughout
              Europe.

         (v)  Morgan Stanley Capital International Japan Index -- an unmanaged
              index of common stocks.

         (w)  Morgan Stanley Capital International Latin America Index -- a
              broad-based market capitalization-weighted composite index
              covering at least 60% of markets in Mexico, Argentina, Brazil,
              Chile, Colombia, Peru and Venezuela (assumes dividends
              reinvested).

         (x)  Morgan Stanley Capital International World Index -- an
              arithmetic, market value-weighted average of the performance of
              over 1,470 securities listed on the stock exchanges of countries
              in Europe, Australia, the Far East, Canada and the United States.

         (y)  NASDAQ Composite Index -- an unmanaged index of common stocks.

         (z)  NASDAQ Industrial Index -- a capitalization-weighted index
              composed of more than 3,000 domestic stocks taken from the
              following industry sectors: agriculture, mining, construction,
              manufacturing, electronic components, services and public
              administration enterprises.  It is a value-weighted index
              calculated on price change only and does not include income.

    

                                          40

<PAGE>

   

         (aa) National Association of Real Estate Investment Trusts ("NAREIT")
              Index -- an unmanaged market weighted index of tax qualified
              REITs (excluding healthcare REITs) listed on the New York Stock
              Exchange, American Stock Exchange and the NASDAQ National Market
              System including dividends.

         (bb) The New York Stock Exchange composite or component indices --
              unmanaged indices of all industrial, utilities, transportation
              and finance company stocks listed on the New York Stock Exchange.

         (cc) Philadelphia Gold and Silver Index -- an unmanaged index
              comprised of seven leading companies involved in the  mining of
              gold and silver.

         (dd) Russell 2500 Index -- comprised of the bottom 500 stocks in the
              Russell 1000 Index which represents the universe of stocks from
              which most active money managers typically select; and all the
              stocks in the Russell 2000 Index. The largest security in the
              index has a market capitalization of approximately 1.3 billion.

         (ee) Salomon Brothers GNMA Index -- includes pools of mortgages
              originated by private lenders and guaranteed by the mortgage
              pools of the Government National Association.

         (ff) Salomon Brothers High Grade Corporate Bond Index -- consists of
              publicly issued, non-convertible corporate bonds rated AA or AAA.
              It a is value-weighted, total return index, including
              approximately 800 issues with maturities of 12 years or greater.

         (gg) Salomon Brothers Broad Investment Grade Bond -- a market-weighted
              index that contains approximately 4700 individually priced
              investment grade corporate bonds rated BBB or better, U.S.
              Treasury/agency issues and mortgage pass-through securities.

         (hh) Standard & Poor's 500 Stock Index or its component indices --
              unmanaged index composed of 400 industrial stocks, 40 financial
              stocks, 40 utilities company stocks and 20 transportation stocks.
              Comparisons of performance assume reinvestment of dividends.

         (ii) Standard & Poor's Small Cap 600 Index -- a capitalization-
              weighted index of 600 domestic stocks having market
              capitalizations which reside within the 50th and the 83rd
              percentiles of the market capitalization of the entire stock
              market, chosen for certain liquidity characteristics and for
              industry representation.

         (jj) Wilshire 5000 Equity Index or its component indices -- represents
              the return on the market value of all common equity securities
              for which daily pricing is available.  Comparisons of performance
              assume reinvestment of dividends.

    

       In assessing such comparisons of performance an investor should keep in
mind that the composition of the investments in the reported indices and
averages is not identical to the composition of investments in the Fund's
Portfolios, that the averages are generally unmanaged, and that the items
included in the calculations of such averages may not be identical to the
formula used by the Fund to calculate its futures.  In addition, there can be no
assurance that the Fund will continue this performance as compared to such other
averages.


                                 GENERAL INFORMATION

DESCRIPTION OF SHARES AND VOTING RIGHTS

   

       The Fund's Articles of Incorporation, as amended and restated, permit
the Directors to issue shares 34 billion of common stock, par value $.001 per
share, from an unlimited number of classes ("Portfolios") of shares.  Currently
the Fund consists of shares of twenty-eight Portfolios (China Growth, Mortgage-
Backed Securities, MicroCap and International Magnum Portfolios are not
currently offering shares).

    

       The shares of each Portfolio of the Fund are fully paid and
nonassessable, and have no preference as to conversion, exchange, dividends,
retirement or other features.  The shares of each Portfolio of the Fund have no
pre-emptive rights.  The shares of the Fund have non-cumulative voting rights,
which means that the holders of more than 50% of the shares voting for the
election

                                          41

<PAGE>

of Directors can elect 100% of the Directors if they choose to do so.  A
shareholder is entitled to one vote for each full share held (and a fractional
vote for each fractional share held), then standing in his name on the books of
the Fund.

DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS

       The Fund's policy is to distribute substantially all of each Portfolio's
net investment income, if any.  The Fund may also distribute any net realized
capital gains in the amount and at the times that will avoid both income
(including taxable gains) taxes on it and the imposition of the federal excise
tax on income and capital gains (see discussion under "Taxes" in this Statement
of Additional Information).  However, the Fund may also choose to retain net
realized capital gains and pay taxes on such gains.  The amounts of any income
dividends or capital gains distributions cannot be predicted.

       Any dividend or distribution paid shortly after the purchase of shares
of a Portfolio by an investor may have the effect of reducing the per share net
asset value of that Portfolio by the per share amount of the dividend or
distribution.  Furthermore, such dividends or distributions, although in effect
a return of capital, are subject to income taxes for shareholders subject to tax
as set forth herein and in the applicable Prospectus.

   

       As set forth in the Prospectuses, unless the shareholder elects
otherwise in writing, all dividends and capital gains distributions for a class
of shares are automatically received in additional shares of such class of that
Portfolio of the Fund at net asset value (as of the business day following the
record date).  This automatic reinvestment of dividends and distributions will
remain in effect until the Fund is notified by the shareholder in writing at
least three days prior to the record date that either the Income Option (income
dividends in cash and capital gains distributions in additional shares at net
asset value) or the Cash Option (both income dividends and capital gains
distributions in cash) has been elected.

CUSTODY ARRANGEMENTS

       Chase serves as the Fund's domestic custodian.  Chase is not affiliated
with Morgan Stanley & Co. Incorporated.  Morgan Stanley Trust Company, Brooklyn,
NY, acts as the Fund's custodian for foreign assets held outside the United
States and employs subcustodians who were approved by the Directors of the Fund
in accordance with Rule 17f-5 adopted by the Commission under the 1940 Act.
Morgan Stanley Trust Company is an affiliate of Morgan Stanley & Co.
Incorporated.  In the selection of foreign subcustodians, the Directors consider
a number of factors, including, but not limited to, the reliability and
financial stability of the institution, the ability of the institution to
provide efficiently the custodial services required for the Fund, and the
reputation of the institution in the particular country or region.

    

                        DESCRIPTION OF SECURITIES AND RATINGS

I.  DESCRIPTION OF COMMERCIAL PAPER AND BOND RATINGS

       EXCERPTS FROM MOODY'S INVESTORS SERVICE, INC. ("MOODY'S") DESCRIPTION OF
BOND RATINGS:  Aaa - Bonds which are rated Aaa are judged to be the best
quality. They carry the smallest degree of investment risk and are generally
referred to as "gilt-edge." Interest payments are protected by a large or by an
exceptionally stable margin, and principal is secure.  While the various
protective elements are likely to change, such changes as can be visualized are
most unlikely to impair the fundamentally strong position of such issues.  Aa -
Bonds which are rated Aa are judged to be of high quality by all standards.
Together with the Aaa group they comprise what are generally known as high grade
bonds.  They are rated lower than the best bonds because margins of protection
may not be as large as in Aaa securities or fluctuation of protective elements
may be of greater amplitude or there may be other elements present which make
the long-term risks appear somewhat larger than in Aaa securities.  Moody's
applies numerical modifiers 1, 2 and 3 in the Aa and A rating categories.  The
modifier 1 indicates that the security ranks at a higher end of the rating
category, modifier 2 indicates a mid-range rating and the modifier 3 indicates
that the issue ranks at the lower end of the rating category.  A - Bonds which
are rated A possess many favorable investment attributes and are to be
considered as upper medium grade obligations.  Factors giving security to
principal and interest are considered adequate but elements may be present which
suggest a susceptibility to impairment sometime in the future.  Baa - Bonds
which are rated Baa are considered as medium grade obligations, i.e., they are
neither highly protected nor poorly secured. Interest payments and principal
security appear adequate for the present but certain protective elements may be
lacking or may be characteristically unreliable over any great length of time.
Such bonds lack outstanding investment characteristics and in fact have
speculative characteristics as well.  Ba - Bonds which are rated Ba are judged
to have speculative elements; their future cannot be considered as well assured.
Often the protection of interest and principal payments may be very moderate,
and thereby not well safeguarded during both good and bad times over the future.
Uncertainty of position characterizes bonds in this class.  B - Bonds which are
rated B generally lack characteristics of the desirable investment.  Assurance
of interest

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<PAGE>

and principal payments or of maintenance of other terms of the contract over any
long period of time may be small.  Caa - Bonds which are rated Caa are of poor
standing.  Such issues may be in default or there may be present elements of
danger with respect to principal or interest.  Ca - Bonds which are rated Ca
represent obligations which are speculative in a high degree.  Such issues are
often in default or have other marked shortcomings.
C - Bonds which are rated C are the lowest rated class of bonds, and issues so
rated can be regarded as having extremely poor prospects of ever attaining any
real investment standing.

       EXCERPTS FROM STANDARD & POOR'S RATINGS GROUP ("S&P") DESCRIPTION OF BOND
RATINGS: AAA - Bonds rated AAA have the highest rating assigned by Standard &
Poor's to a debt obligation and indicate an extremely strong capacity to pay
principal and interest.  AA - Bonds rated AA have a very strong capacity to pay
interest and repay principal and differ from the highest rated issues only to a
small degree.  A - Bonds rated A have a strong capacity to pay interest and
repay principal although they are somewhat more susceptible to the adverse
effects of changes in circumstances and economic conditions than bonds in higher
rated categories.  BBB - Debt rated BBB is regarded as having an adequate
capacity to pay interest and repay principal.  Whereas it normally exhibits
adequate protection parameters, adverse economic conditions or changing
circumstances are more likely to lead to a weakened capacity to pay interest and
repay principal for debt in this category than for debt in higher rated
categories.  BB, B, CCC, CC - Debt rated BB, B, CCC and CC is regarded, on
balance, as predominantly speculative with respect to capacity to pay interest
and repay principal in accordance with the terms of the obligation.  BB
indicates the lowest degree of speculation and CC the highest degree of
speculation.  While such debt will likely have some quality and protective
characteristics, these are outweighed by large uncertainties or major risk
exposures to adverse conditions.  C - The rating C is reserved for income bonds
on which no interest is being paid.  D - Debt rated D is in default, and payment
of interest and/or repayment of principal is in arrears.

       DESCRIPTION OF MOODY'S RATINGS OF STATE AND MUNICIPAL NOTES:  Moody's
ratings for state and municipal notes and other short-term obligations are
designated Moody's Investment Grade ("MIG").  Symbols used are as follows:
MIG-1 -- best quality, enjoying strong protection from established cash flows of
funds for their servicing or from established broad-based access to the market
for refinancing, or both; MIG-2 -- high quality with margins of protection ample
although not so large as in the preceding group; MIG-3 - favorable quality, with
all security elements accounted for but lacking the undeniable strength of the
preceding grades.

       DESCRIPTION OF MOODY'S HIGHEST COMMERCIAL PAPER RATING:  Prime-1 ("P1")
- -- Judged to be of the best quality.  Their short-term debt obligations carry
the smallest degree of investment risk.

       EXCERPT FROM S&P'S RATING OF MUNICIPAL NOTE ISSUES:  S-1+ -- very strong
capacity to pay principal and interest; SP-2 -- strong capacity to pay principal
and interest.

       DESCRIPTION OF S&P'S HIGHEST COMMERCIAL PAPER RATINGS:  A-1+ -- this
designation indicates the degree of safety regarding timely payment is
overwhelming.  A-1 -- this designation indicates the degree of safety regarding
timely payment is very strong.

II.  DESCRIPTION OF U.S. GOVERNMENT SECURITIES

       The term "U.S. Government securities" refers to a variety of securities
which are issued or guaranteed by the U.S. Government, and by various
instrumentalities which have been established or sponsored by the U.S.
Government.

       U.S. Treasury securities are backed by the "full faith and credit" of
the United States. Securities issued or guaranteed by Federal agencies and U.S.
Government sponsored instrumentalities may or may not be backed by the full
faith and credit of the United States.  In the case of securities not backed by
the full faith and credit of the United States, the investor must look
principally to the agency or instrumentality issuing or guaranteeing the
obligation for ultimate repayment, and may not be able to assert a claim against
the United States itself in the event the agency or instrumentality does not
meet its commitment. Agencies which are backed by the full faith and credit of
the United States include the Export-Import Bank, Farmers Home Administration,
Federal Financing Bank, and others.  Certain agencies and instrumentalities,
such as the Government National Mortgage Associates, are, in effect, backed by
the full faith and credit of the United States through provisions in their
charters that they may make "indefinite and unlimited" drawings on the Treasury,
if needed to service debt.  Debt from certain other agencies and
instrumentalities, including the Federal Home Loan Bank and Federal National
Mortgage Association, are not guaranteed by the United States, but those
institutions are protected by the discretionary authority for the U.S. Treasury
to purchase certain amounts of their securities to assist the institution in
meeting its debt obligations.  However, the U.S. Treasury has no lawful
obligation to assume the financial liabilities of these agencies or others.
Finally, other agencies and instrumentalities, such as the Farm Credit System
and the Federal Home Loan Mortgage Corporation, are federally chartered
institutions under Government supervision, but their debt securities are backed
only by the creditworthiness of those institutions, not the U.S. Government.

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<PAGE>

       Some of the U.S. Government agencies that issue or guarantee securities
include the Export-Import Bank of the United States, Farmers Home
Administration, Federal Housing Administration, Maritime Administration, Small
Business Administration, and the Tennessee Valley Authority.

       An instrumentality of the U.S. Government is a Government agency
organized under Federal charter with Government supervision.  Instrumentalities
issuing or guaranteeing securities include, among others, Federal Home Loan
Banks, the Federal Land Banks, Central Bank for Cooperatives, Federal Immediate
Credit Banks, and the Federal National Mortgage Association.

III.  DESCRIPTION OF MUNICIPAL BONDS

       Municipal Bonds generally include debt obligations issued by states and
their political subdivisions, and duly constituted authorities and corporations,
to obtain funds to construct, repair or improve various public facilities such
as airports, bridges, highways, hospitals, housing, schools, streets and water
and sewer works.  Municipal Bonds may also be issued to refinance outstanding
obligations as well as to obtain funds for general operating expenses and for
loans to other public institutions and facilities.

       The two principal classifications of Municipal Bonds are "general
obligation" and "revenue" or "special tax" bonds.  General obligation bonds are
secured by the issuer's pledge of its full faith, credit and taxing power for
the payment of principal and interest.  Revenue or special tax bonds are payable
only from the revenues derived from a particular facility or class of facilities
or, in some cases, from the proceeds of a special excise or other tax, but not
from general tax revenues.  The Municipal Bond Portfolio and the Municipal Money
Market Portfolio may also invest in tax-exempt industrial development bonds,
short-term municipal obligations, project notes, demand notes and tax-exempt
commercial paper in accordance with the Portfolio's investment objectives and
policies.

       Industrial revenue bonds (i.e., private activity bonds) in most cases
are revenue bonds and generally do not have the pledge of the credit of the
issuer.  The payment of the principal and interest on such industrial revenue
bonds is dependent solely on the ability of the user of the facilities financed
by the bonds to meet its financial obligations and the pledge, if any, of real
and personal property so financed as security for such payment.  Short-term
municipal obligations issued by states, cities, municipalities or municipal
agencies include Tax Anticipation Notes, Revenue Anticipation Notes, Bond
Anticipation Notes, Construction Loan Notes and Short-Term Discount Notes.
Project Notes are instruments guaranteed by the Department of Housing and Urban
Development but issued by a state or local housing agency.  While the issuing
agency has the primary obligation on such Project notes, they are also secured
by the full faith and credit of the United States.

       Note obligations with demand or put options may have a stated maturity
in excess of one year, but allow any holder to demand payment of principal plus
accrued interest upon a specified number of days' notice.  Frequently, such
obligations are secured by letters of credit or other credit support
arrangements provided by banks.  The issuer of such notes normally has a
corresponding right, after a given period, to repay in its discretion the
outstanding principal of the notes plus accrued interest upon a specific number
of days' notice to the bondholders.  The interest rate on a demand note may be
based upon a known lending rate, such as a bank's prime rate, and be adjusted
when such rate changes, or the interest rate on a demand note may be a market
rate that is adjusted at specified intervals.  The demand notes in which the
Municipal Money Market Portfolio will invest are payable on not more than one
year's notice.

       The yields of Municipal Bonds depend on, among other things, general
money market conditions, conditions in the Municipal Bond market, the size of a
particular offering, the maturity of the obligation, and the rating of the
issue.  The ratings of Moody's and S&P represent their opinions of the quality
of the Municipal Bonds.  It should be emphasized that such ratings are general
and are not absolute standards of quality.  Consequently, Municipal Bonds with
the same maturity, coupon and rating may have different yields, while Municipal
Bonds of the same maturity and coupon, but with different ratings, may have the
same yield.  It will be the responsibility of the Adviser to appraise
independently the fundamental quality of the bonds held by the Municipal Bond
Portfolio and the Municipal Money Market Portfolio.

       Municipal Bonds are sometimes purchased on a "when issued" basis meaning
the buyer has committed to purchasing certain specified securities at an
agreed-upon price when they are issued.  The period between commitment date and
issuance date can be a month or more.  It is possible that the securities will
never be issued and the commitment canceled.

       From time to time proposals have been introduced before Congress to
restrict or eliminate the Federal income tax exemption for interest on Municipal
Bonds.  Similar proposals may be introduced in the future.  If any such proposal
were enacted, it might restrict or eliminate the ability of either the Municipal
Bond Portfolio or the Municipal Money Market Portfolio to achieve its investment
objective.  In that event, the Fund's Directors and officers would reevaluate
its investment objective and policies and consider recommending to its
shareholders changes in such objective and policies.

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<PAGE>

       Similarly, from time to time proposals have been introduced before State
and local legislatures to restrict or eliminate the State and local income tax
exemption (to the extent such an exemption applies, which may not apply in all
cases) for interest on Municipal Bonds.  Similar proposals may be introduced in
the future.  If any such proposal were enacted, it might restrict or eliminate
the ability of either of the Municipal Bond Portfolio or the Municipal Money
Market Portfolio to achieve its investment objective.  In that event, the Fund's
Directors and officers would reevaluate the Portfolio's investment objective and
policies and consider recommending to its shareholders changes in such objective
and policies.

IV.  DESCRIPTION OF MORTGAGE-BACKED SECURITIES

       "Mortgage-Backed Securities" are securities that, directly or
indirectly, represent a participation in, or are secured by and payable from,
mortgage loans on real property.  Mortgage-backed securities include
collateralized mortgage obligations ("CMOs"), pass-through securities issued or
guaranteed by agencies or instrumentalities of the U.S. government or by private
sector entities.

       COLLATERALIZED MORTGAGE OBLIGATIONS.  Collateralized mortgage
obligations ("CMOs") are debt obligations or multiclass pass-through
certificates issued by agencies or instrumentalities of the U.S. government or
by private originators or investors in mortgage loans.  They are backed by
Mortgage Pass-Through Securities (discussed below) or whole loans (all such
assets, the "Mortgage Assets") and are evidenced by a series of bonds or
certificates issued in multiple classes or "tranches."  The principal and
interest on the underlying Mortgage Assets may be allocated among the several
classes of a series of CMOs in many ways.

       CMOs may be issued by agencies or instrumentalities of the U.S.
government, or by private originators of, or investors in, mortgage loans,
including savings and loan associations, mortgage bankers, commercial banks,
investment banks and special purpose subsidiaries of the foregoing.  CMOs that
are issued by private sector entities and are backed by assets lacking a
guarantee of an entity having the credit status of a governmental agency or
instrumentality are generally structured with one or more types of credit
enhancement as described below.  An issuer of CMOs may elect to be treated, for
federal income tax purposes, as a Real Estate Mortgage Investment Conduit (a
"REMIC").  An issuer of CMOs issued after 1991 must elect to be treated as a
REMIC or it will be taxable as a corporation under rules regarding taxable
mortgage pools.

       In a CMO, a series of bonds or certificates are issued in multiple
classes.  Each class of CMOs, often referred to as a "tranche," may be issued
with a specific fixed or floating coupon rate and has a stated maturity or final
scheduled distribution date.  Principal prepayments on the underlying Mortgage
Assets may cause the CMOs to be retired substantially earlier than their stated
maturities or final scheduled distribution dates.  Interest is paid or accrues
on CMOs on a monthly, quarterly or semi-annual basis.  The principal of and
interest on the Mortgage Assets may be allocated among the several classes of a
CMO in many ways.  The general goal in allocating cash flows on Mortgage Assets
to the various classes of a CMO is to create certain tranches on which the
expected cash flows have a higher degree of predictability than the underlying
Mortgage Assets.  As a general matter, the more predictable the cash flow is on
a particular CMO tranche, the lower the anticipated yield will be on that
tranche at the time of issuance relative to prevailing market yields on Assets.
As part of the process of creating more predictable cash flows on certain
tranches of a CMO, one or more tranches generally must be created that absorb
most of the changes in the cash flows on the underlying Mortgage Assets.  The
yields on these tranches are generally higher than prevailing market yields on
Mortgage-Backed Securities with similar average lives.  Because of the
uncertainty of the cash flows on these tranches, the market prices of and yields
on these tranches are more volatile.

       Included within the category of CMOs are PAC Bonds.  PAC Bonds are a
type of CMO tranche or series designed to provide relatively predictable
payments of principal provided that, among other things, the actual prepayment
experience on the underlying mortgage loans falls within a predefined range.  If
the actual prepayment experience on the underlying mortgage loans is at a rate
faster or slower than the predefined range or if deviations from other
assumptions occur, principal payments on the PAC Bond may be earlier or later
than predicted.  The magnitude of the predefined range varies from one PAC Bond
to another; a narrower range increases the risk that prepayments on the PAC Bond
will be greater or smaller than predicted.  Because of these features, PAC Bonds
generally are less subject to the risks of prepayment than are other types of
mortgage-backed securities.

        MORTGAGE PASS-THROUGH SECURITIES.  Mortgage pass-through securities in
which the Mortgage-Backed Securities Portfolio may invest include pass-through
securities issued or guaranteed by agencies or instrumentalities of the U.S.
government or by private sector entities.  Mortgage pass-through securities
issued or guaranteed by private sector originators of or investors in mortgage
loans and are structured similarly to governmental pass-through securities.
Because private pass-throughs typically lack a guarantee by an entity having the
credit status of a governmental agency or instrumentality, they are generally
structured with one or more types of credit enhancement described below.  FNMA
and FHLMC obligations are not backed by the full faith and credit of the U.S.
government as GNMA certificates are, but FNMA and FHLMC securities are supported
by the instrumentalities' right to borrow from the United States Treasury.  Each
of GNMA, FNMA and FHLMC guarantees timely distributions of interest to
certificate holders.

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<PAGE>

Each of GNMA and FNMA also guarantees timely distributions of scheduled
principal.  FHLMC has in the past guaranteed only the ultimate collection of
principal of the underlying mortgage loan; however, FHLMC now issued Mortgage-
Backed Securities (FHLMC Gold Pcs) which also guarantee timely payment of
monthly principal reductions.  REFCORP obligations are backed, as to principal
payments, by zero coupon U.S. Treasury bonds, and as to interest payment,
ultimately by the U.S. Treasury.  Obligations issued by such U.S. governmental
agencies and instrumentalities are described more fully below.

       GINNIE MAE CERTIFICATES.  Ginnie Mae is a wholly-owned corporate
instrumentality of the United States within the Department of Housing and Urban
Development.  The National Housing Act of 1934, as amended (the "Housing Act"),
authorizes Ginnie Mae to guarantee the timely payment of the principal of and
interest on certificates that are based on and backed by a pool of mortgage
loans insured by the Federal Housing Administration under the Housing Act, or
Title V of the Housing Act of 1949 ("FHA Loans"), or guaranteed by the
Department of Veterans Affairs under the Servicemen's Readjustment Act of 1944,
as amended ("VA Loans"), or by pools of other eligible mortgage loans.  The
Housing Act provides that the full faith and credit of the United States
government is pledged to the payment of all amounts that may be required to be
paid under any guaranty.  In order to meet its obligations under such guaranty,
Ginnie Mae is authorized to borrow from the United States Treasury with no
limitations as to amount.

       Each Ginnie Mae Certificate will represent a pro rata interest in one or
more of the following types of mortgage loans: (i) fixed rate level payment
mortgage loans; (ii) fixed rate graduated payment mortgage loans; (iii) fixed
rate growing equity mortgage loans; (iv) fixed rate mortgage loans secured by
manufactured (mobile) homes; (v) mortgage loans on multi-family residential
properties under construction; (vi) mortgage loans on completed multi-family
projects; (vii) fixed rate mortgage loans as to which escrowed funds are used to
reduce the borrower's monthly payments during the early years of the mortgage
loans ("buydown" mortgage loans); (viii) mortgage loans that provide for
adjustments in payments based on periodical changes in interest rates or in
other payment terms of the mortgage loans; and (ix) mortgage-backed serial
notes.  All of these mortgage loans will be FHA Loans or VA Loans and, except as
otherwise specified above, will be fully-amortizing loans secured by first liens
on one- to four-family housing units.

       FANNIE MAE CERTIFICATES.  Fannie Mae is a federally chartered and
privately owned corporation organized and existing under the Federal National
Mortgage Association Charter Act of 1938.  The obligations of Fannie Mae are not
backed by the full faith and credit of the United States government.

       Each Fannie Mae Certificate will represent a pro rata interest in one or
more pools of FHA Loans, VA Loans or conventional mortgage loans (i.e., mortgage
loans that are not insured or guaranteed by any governmental agency) of the
following types: (i) fixed rate level payment mortgage loans; (ii) fixed rate
growing equity mortgage loans; (iii) fixed rate graduated payment mortgage
loans; (iv) variable rate California mortgage loans; (v) other adjustable rate
mortgage loans; and (vi) fixed rate and adjustable mortgage loans secured by
multi-family projects.

       FREDDIE MAC CERTIFICATES.  Freddie Mac is a corporate instrumentality of
the United States created pursuant to the Emergency Home Finance Act of 1970, as
amended (the "FHLMC Act").  The obligations of Freddie Mac are obligations
solely of Freddie Mac and are not backed by the full faith and credit of the
U.S. government.

       Freddie Mac Certificates represent a pro rata interest in a group of
mortgage loans (a "Freddie Mac Certificate group") purchased by Freddie Mac.
The mortgage loans underlying the Freddie Mac Certificates will consist of fixed
rate or adjustable rate mortgage loans with original terms to maturity of
between ten and thirty years, substantially all of which are secured by first
liens on one- to four-family residential properties or multi-family projects.
Each mortgage loan must meet the applicable standards set forth in the FHLMC
Act.  A Freddie Mac Certificate group may include whole loans, participation
interests in whole loans and undivided interests in whole loans and
participations comprising another Freddie Mac Certificate group.

       CREDIT ENHANCEMENT.  Mortgage-backed securities are often backed by a
pool of assets representing the obligations of a number of different parties.
To lessen the effect of failure by obligors on underlying assets to make
payments, such securities may contain elements of credit support.  Such credit
support falls into two categories: (i) liquidity protection and (ii) protection
against losses resulting from ultimate default by an obligor on the underlying
assets.  Liquidity protection generally refers to the provision of advances,
typically by the entity administering the pool of assets, to ensure that the
pass-through of payments due on the underlying pool occurs in a timely fashion.
Protection against losses resulting from ultimate default enhances the
likelihood of ultimate payment of the obligations on at least a portion of the
assets in the pool.  Such protection may be provided through guarantees,
insurance policies or letters of credit obtained by the issuer or sponsor from
third parties (referred to herein as "third party credit support"), through
various means of structuring the transaction or through a combination of such
approaches.  The Mortgage-Backed Securities Portfolio will not pay any
additional fees for such credit support, although the existence of credit
support may increase the price the Portfolio pays for a security.

                                          46

<PAGE>

       The ratings of mortgage-backed securities for which third-party credit
enhancement provides liquidity protection or protection against losses from
default are generally dependent upon the continued creditworthiness of the
provider of the credit enhancement.  The ratings of such securities could be
subject to reduction in the event of deterioration in the creditworthiness of
the credit enhancement provider even in cases where the delinquency and loss
experience on the underlying pool of assets is better than expected.

       Examples of credit support arising out of the structure of the
transaction include "senior-subordinated securities" (multiple class securities
with one or more classes subordinate to other classes as to the payment of
principal thereof and interest thereon, with defaults on the underlying assets
being borne first by the holders of the most subordinated class), creation of
"reserve funds" (where cash or investments, sometimes funded from a portion of
the payments on the underlying assets, are held in reserve against future
losses) and "over-collateralization" (where the scheduled payments on, or the
principal amount of, the underlying assets exceed those required to make payment
of the securities and pay any servicing or other fees).  The degree of credit
support provided for each security is generally based on historical information
with respect to the level of credit risk associated with the underlying assets.
Delinquency or loss in excess of that which is anticipated could adversely
affect the return on an investment in such a security.

V.  FOREIGN INVESTMENTS

   

       The Active Country Allocation, International Equity, International Fixed
Income, Global Equity, Global Fixed Income, Asian Equity, European Equity,
Japanese Equity, International Small Cap, Latin American and China Growth
Portfolios will invest, and the Emerging Growth, Emerging Markets, Emerging
Markets Debt, Value Equity, Equity Growth, MicroCap, Balanced, Small Cap Value
Equity, International Magnum, Fixed Income, High Yield and Gold Portfolios may
invest, in securities of foreign issuers.  Investors should recognize that
investing in such foreign securities involves certain special considerations
which are not typically associated with investing in U.S. issuers. For a
description of the effect on the Portfolios of currency exchange rate
fluctuation, see "Investment Objectives and Policies -- Forward Foreign Currency
Exchange Contracts" above.  As foreign issuers are not generally subject to
uniform accounting, auditing and financial reporting standards and may have
policies that are not comparable to those of domestic issuers, there may be less
information available about certain foreign companies than about domestic
issuers.  Securities of some foreign issuers are generally less liquid and more
volatile than securities of comparable domestic issuers.  There is generally
less government supervision and regulation of stock exchanges, brokers and
listed issuers than in the U.S.  In addition, with respect to certain foreign
countries, there is the possibility of expropriation or confiscatory taxation,
political or social instability, or diplomatic developments which could affect
U.S. investments in those countries.  Foreign securities not listed on a
recognized domestic or foreign exchange are regarded as not readily marketable
and therefore such investments will be limited to 15% of a Portfolio's net asset
value at the time of purchase.

       Although the Portfolios will endeavor to achieve the most favorable
execution costs in their portfolio transactions, fixed commissions on many
foreign stock exchanges are generally higher than negotiated commissions on U.S.
exchanges.

       Certain foreign governments levy withholding or other taxes on dividend
and interest income.  Although in some countries a portion of these taxes are
recoverable, the non-recovered portion of foreign withholding taxes will reduce
the income received from investments in such countries.  Except in the case of
the International Equity, Global Equity, European Equity, Japanese Equity, Asian
Equity, Global Fixed Income, International Fixed Income, International Magnum,
International Small Cap, Latin American and China Growth Portfolios, it is not
expected that a Portfolio or its shareholders would be able to claim a credit
for U.S. tax purposes with respect to any such foreign taxes.  However, these
foreign withholding taxes may not have a significant impact on such Portfolios,
because each Portfolio's investment objective is to seek long-term capital
appreciation and any dividend or interest income should be considered
incidental.


                                 FINANCIAL STATEMENTS

The following are (i) the audited Financial Statements for the fiscal year ended
December 31, 1995 and the Report of Price Waterhouse LLP, independent
accountants, dated February 9, 1996 relating to the financial statements and
financial highlights of each of the Portfolios except for the Mortgage-Backed
Securities, China Growth, MicroCap and International Magnum Portfolios, which
had not commenced operation as of December 31, 1995.

    

                                          47

<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE ACTIVE COUNTRY ALLOCATION PORTFOLIO
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
COMMON STOCKS (89.5%)
  AUSTRALIA (1.8%)
    15,500  Amcor Ltd.........................................  $      109
     8,800  Ampolex Ltd.......................................          19
    14,600  Australian National Industries Ltd................          11
    24,900  Boral Ltd. (Bonus Shares Plan)....................          63
     6,200  Brambles Industries Ltd...........................          69
    46,670  Broken Hill Proprietary Co., Ltd..................         659
    16,100  Burns, Philip & Co., Ltd..........................          36
     7,981  Coca-Cola Amatil Ltd..............................          64
    32,918  Coles Myer Ltd....................................         103
    16,000  CRA Ltd...........................................         235
  **+1,200  CRA Ltd. (Bonus Shares)...........................          17
    25,100  CSR Ltd...........................................          82
    47,400  Fosters Brewing Corp..............................          78
    +4,278  Goldfields Ltd....................................          11
    33,300  Goodman Fielder Ltd...............................          33
     8,800  ICI Australia Ltd.................................          67
     6,833  Lend Lease Corp., Ltd.............................          99
    41,019  MIM Holdings Ltd..................................          57
    35,518  National Australia Bank Ltd.......................         319
     8,200  Newcrest Mining Ltd...............................          34
    47,600  News Corp., Ltd...................................         254
    22,073  North Broken Hill Peko Ltd........................          62
    28,900  Pacific Dunlop Ltd................................          68
    24,200  Pioneer International Ltd.........................          62
     7,700  Renison Goldfields Consolidated Ltd...............          38
    15,400  Santos Ltd........................................          45
    18,400  Southcorp Holdings Ltd............................          43
   +11,900  TNT Ltd...........................................          16
    26,000  Western Mining Corp. Holdings Ltd.................         167
    43,900  Westpac Banking Corp..............................         194
                                                                ----------
                                                                     3,114
                                                                ----------
  BELGIUM (1.8%)
       120  Bekaert S.A.......................................          99
       200  Cimenteries CBR...................................          81
     2,800  Delhaize Freres et Cie, 'Le Lion' S.A.............         116
     2,400  Electrabel S.A....................................         571
       500  Electrabel S.A. (New).............................         119
     1,700  Fortis AG.........................................         207
       108  Fortis AG VVPR (New)..............................          13
       785  Generale de Banque S.A............................         278
     1,375  Gevaert Photo-Producten S.A.......................          85
       299  Glaverbel S.A.....................................          32
        50  Glaverbel S.A. VVPR (New).........................          --
     1,250  Groupe Bruxelles Lambert S.A......................         173
       700  Kredietbank S.A...................................         191
     1,240  Petrofina S.A.....................................         380
       675  Reunies Electrobel & Tractebel S.A................         279
       700  Royale Belge......................................         140
       450  Solvay et Cie S.A.................................         243
    +1,350  Union Miniere S.A.................................          90
                                                                ----------
                                                                     3,097
                                                                ----------
  BRAZIL (0.5%)
   935,000  Cia Paulista de Forca E Luz.......................          45
 2,211,000  Cia Siderurgica Nacional..........................          46
 
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
 2,721,000  Eletrobras........................................  $      736
   425,000  Light Servicos de Eletricidade....................         136
                                                                ----------
                                                                       963
                                                                ----------
  FRANCE (3.5%)
       600  Accor S.A.........................................          78
     2,800  Alcatel Alsthom...................................         241
     3,100  AXA S.A...........................................         209
     3,800  Banque Nationale de Paris.........................         171
       400  BIC Corp..........................................          41
       600  Bouygues..........................................          60
       450  Canal Plus........................................          84
       500  Carrefour Supermarch S.A..........................         303
     1,700  Casino............................................          49
       150  Chargeurs S.A.....................................          30
       550  Cie Bancaire S.A..................................          62
     1,750  Cie de Saint Gobain...............................         194
     3,400  Cie de Suez S.A...................................         140
     2,500  Cie Financiere de Paribas S.A., Class A...........         137
     2,300  Cie Generale des Eaux.............................         230
  ***5,100  Elf Aquitaine.....................................         376
       700  Eridania Beghin-Say S.A...........................         120
     1,450  Groupe Danone.....................................         239
     1,150  Havas S.A.........................................          91
     2,265  Lafarge Coppee S.A................................         146
     1,300  L'Air Liquide.....................................         215
       550  Legrand...........................................          85
     1,300  L'Oreal...........................................         348
     1,750  LVMH Moet Hennessy Louis Vuitton..................         365
     1,400  Lyonnaise des Eaux................................         135
     2,500  Michelin CGDE, Class B............................         100
     1,200  Pernod-Ricard.....................................          68
     1,100  Peugeot S.A.......................................         145
       400  Pinault-Printemps S.A.............................          80
       350  Promodes..........................................          82
     6,000  Rhone-Poulenc S.A., Class A.......................         129
        90  SAGEM.............................................          51
       250  Saint Louis.......................................          66
  ***2,090  Sanofi............................................         134
     2,700  Schneider S.A.....................................          92
       588  Simco S.A.........................................          56
        62  Simco S.A. RFD....................................           5
       100  Societe Eurafrance S.A............................          34
     1,700  Societe Generale..................................         210
     2,900  Thomson CSF.......................................          65
     4,200  Total S.A., Class B...............................         284
     5,800  Union des Assurances de Paris.....................         151
    +5,300  Usinor Sacilor....................................          69
                                                                ----------
                                                                     5,970
                                                                ----------
  GERMANY (5.1%)
     1,350  AGIV AG...........................................          29
       550  Allianz AG........................................       1,080
       100  AMB Aachener & Muenchener Beteiligungs AG.........          72
       100  Asko Deutsche Kaufhaus AG.........................          52
     1,650  BASF AG...........................................         372
     1,850  Bayer AG..........................................         491
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                             Active Country Allocation Portfolio
 
                                       5
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE ACTIVE COUNTRY ALLOCATION PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
  GERMANY (CONT.)
     6,100  Bayerische Hypotheken und Wechsel Bank AG.........  $      154
     6,250  Bayerische Vereinsbank AG.........................         187
       100  Beiersdorf AG.....................................          69
       100  Bilfinger & Berger AG.............................          38
       150  Brau Und Brunnen AG...............................          23
      +450  Bremer Vulkan Verbund AG..........................          13
        50  CKAG Colonia Konzern AG...........................          42
     2,750  Continental AG....................................          39
     1,250  Daimler-Benz AG...................................         631
       250  Degussa AG........................................          84
    12,300  Deutsche Bank AG..................................         584
    10,600  Dresdner Bank AG..................................         284
       150  Heidelberger Zement AG............................          94
       200  Hochtief AG.......................................          86
       300  Karstadt AG.......................................         123
       200  Kaufhof Holding AG................................          61
    +1,300  Kloeckner-Humboldt-Deutz AG.......................           8
       250  Linde AG..........................................         148
       900  Lufthansa AG......................................         125
       250  MAN AG............................................          69
     1,000  Mannesmann AG.....................................         318
    +4,300  Merck KGAA........................................         175
      +200  Muenchener Rueckver AG (Registered)...............         431
        +9  Muenchener Rueckver AG RFD (New)..................          19
       450  Preussag AG.......................................         127
       850  RWE AG............................................         309
     1,550  SAP AG............................................         240
     1,800  Schering AG.......................................         120
     1,450  Siemens AG........................................         797
      +850  Thyssen AG........................................         155
    12,450  Veba AG...........................................         533
       550  Viag AG...........................................         227
       700  Volkswagen AG.....................................         235
                                                                ----------
                                                                     8,644
                                                                ----------
  HONG KONG (7.1%)
   +48,000  Applied International Holdings....................           4
    60,438  Bank of East Asia Ltd.............................         217
   227,000  Cathay Pacific Airways Ltd........................         346
   170,000  Cheung Kong Holdings Ltd..........................       1,036
   153,000  China Light & Power Co., Ltd......................         704
   124,000  Chinese Estates Holdings..........................          81
    60,000  Dickson Concepts International Ltd................          56
    48,000  Giordano Holdings Ltd.............................          41
  **96,000  Hang Lung Development Co..........................         153
   148,200  Hang Seng Bank Ltd................................       1,327
    14,800  Hong Kong Aircraft Engineering Co., Ltd...........          38
   150,000  Hong Kong & China Gas Co., Ltd....................         242
    99,000  Hong Kong & Shanghai Hotel Ltd....................         143
   855,487  Hong Kong Telecommunications Ltd..................       1,527
   341,198  Hopewell Holdings Ltd.............................         196
   278,000  Hutchison Whampoa Ltd.............................       1,693
    80,000  Hysan Development Co., Ltd........................         212
    30,000  Johnson Electric Holdings Ltd.....................          54
    45,000  Miramar Hotel & Investment Ltd....................          95
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
 
   114,656  New World Development Co., Ltd....................  $      500
   110,000  Oriental Press Group Ltd..........................          33
    30,500  Peregrine Investment Holdings Ltd.................          39
    84,340  Shangri-La Asia Ltd...............................         103
   126,000  Shun Tak Holdings Ltd.............................          89
   144,000  South China Morning Post Holdings.................          88
    80,000  Stelux Holdings Ltd...............................          20
   177,000  Sun Hung Kai Properties Ltd.......................       1,448
   124,000  Swire Pacific Ltd., Class A.......................         962
    33,000  Television Broadcasts Ltd.........................         118
   168,000  Wharf Holdings Ltd................................         560
    11,800  Wing Lung Bank Ltd................................          66
    27,000  Winsor Industrial Corp............................          23
                                                                ----------
                                                                    12,214
                                                                ----------
  INDONESIA (2.2%)
 **212,000  Bank Dagang Nasional (Foreign)....................         174
 **761,000  Barito Pacific Timber (Foreign)...................         557
 **372,000  Gadjah Tunggal (Foreign)..........................         207
 **212,000  Hanajaya Mandala Sampoerna (Foreign)..............       2,207
 **248,000  Jakarta International Hotel & Development
              (Foreign).......................................         304
  **27,000  Matahari Putra Prima (Foreign)....................          48
 +**17,000  Pan Brothers Tex (Foreign)........................           4
 **104,000  Sinar Mas Agro (Foreign)..........................          58
  **95,000  United Tractors (Foreign).........................         179
                                                                ----------
                                                                     3,738
                                                                ----------
  ITALY (1.8%)
    22,770  Assicurazioni Generali S.p.A......................         551
    45,000  Banca Commerciale Italiana........................          96
    14,000  Banco Ambrosiano Ven..............................          38
     5,000  Benetton Group S.p.A..............................          60
     3,000  Cartiere Burgo....................................          15
    65,500  Credito Italiano..................................          76
    18,000  Edison S.p.A......................................          78
    +2,000  Falck.............................................           5
    89,000  Fiat S.p.A........................................         289
    22,000  Fiat S.p.A. Di Risp (NCS).........................          39
    12,500  Fidis.............................................          24
    +6,000  Impregilo S.p.A...................................           5
    17,400  Instituto Mobiliare Italiano......................         110
    22,000  Istituto Bancario San Paolo.......................         130
   113,700  Istituto Nazionale delle Assicurazioni............         151
     3,250  Italcementi.......................................           8
     7,250  Italcementi Di Risp...............................          43
    19,000  Italgas...........................................          58
    10,900  Magneti Marelli S.p.A.............................          13
    14,500  Mediobanca S.p.A..................................         100
  +150,000  Montedison S.p.A..................................         101
   +20,000  Montedison S.p.A. Di Risp (NCS)...................          12
  +106,250  Olivetti S.p.A....................................          85
    35,600  Parmalat Finanziaria S.p.A........................          31
   +45,000  Pirelli S.p.A.....................................          58
     7,150  R.A.S. S.p.A......................................          81
     3,100  R.A.S. S.p.A Di Risp (NCS)........................          19
     6,000  Rinascente........................................          36
    +2,000  Saffa S.p.A.......................................           5
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Active Country Allocation Portfolio
 
                                       6
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE ACTIVE COUNTRY ALLOCATION PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
  ITALY (CONT.)
     3,500  SAI...............................................  $       36
    12,500  Saipem............................................          29
     3,000  Sasib.............................................          13
     7,000  Sirti S.p.A.......................................          39
   +20,000  SNIA BPD S.p.A....................................          17
  +183,700  Telecom Italia Mobile S.p.A.......................         323
   180,000  Telecom Italia S.p.A..............................         280
    45,000  Telecom Italia S.p.A. Di Risp (NCS)...............          55
                                                                ----------
                                                                     3,109
                                                                ----------
  JAPAN (41.9%)
     4,000  Advantest Corp....................................         205
    44,000  Ajinomoto Co......................................         490
    22,000  Aoki Corp.........................................          92
     3,000  Aoyama Trading Co.................................          96
    89,000  Asahi Bank Ltd....................................       1,121
    22,000  Asahi Breweries Ltd...............................         260
    66,000  Asahi Chemical Industry Co., Ltd..................         505
    66,000  Asahi Glass Co., Ltd..............................         735
    66,000  Bank of Tokyo.....................................       1,157
    22,000  Bridgestone Co....................................         350
    62,000  Canon, Inc........................................       1,123
    34,000  Casio Computer Co.................................         333
    36,000  Chiba Bank........................................         324
     9,000  Chiyoda Corp......................................          89
    22,000  Chugai Pharmaceuticals Co.........................         211
    34,000  Citizen Watch Co., Ltd............................         260
    31,000  Daiei Inc.........................................         375
   102,000  Dai-Ichi Kangyo Bank..............................       2,006
    22,000  Daikin Industries Ltd.............................         215
    44,000  Dai Nippon Printing Co., Ltd......................         746
   +10,000  Daishowa Paper Manufacturing Co., Ltd.............          78
    22,000  Daiwa House Industry..............................         362
    44,000  Daiwa Securities Co., Ltd.........................         673
    15,000  Ebara Corp........................................         220
    10,300  Fanuc.............................................         446
   100,000  Fuji Bank.........................................       2,208
    32,000  Fuji Photo Film Ltd...............................         924
   123,000  Fujitsu Ltd.......................................       1,370
    36,000  Furukawa Electric Co..............................         176
    44,000  Hankyu Corp.......................................         241
    22,000  Hazama Corp.......................................          94
   175,000  Hitachi Ltd.......................................       1,763
    57,000  Honda Motor Co....................................       1,176
    71,000  Industrial Bank of Japan..........................       2,152
    11,000  Ito-Yokado Co., Ltd...............................         678
   +89,000  Japan Airlines Co.................................         591
    56,000  Japan Energy Corp.................................         188
    24,000  Joyo Bank.........................................         193
    18,000  Jusco Co., Ltd....................................         469
    44,000  Kajima Corp.......................................         435
    31,928  Kansai Electric Power Co..........................         773
    44,000  Kao Corp..........................................         546
   114,000  Kawasaki Steel Corp...............................         398
    66,000  Kinki Nippon Railway..............................         499
    44,000  Kirin Brewery Co., Ltd............................         520
  +133,000  Kobe Steel Ltd....................................         411
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
    94,000  Komatsu Ltd.......................................  $      774
    66,000  Kubota Corp.......................................         425
    44,000  Kumagai Gumi Co...................................         177
     7,000  Kyocera Ltd.......................................         520
    22,000  Kyowa Hakko Kogyo.................................         208
    12,000  Kyushu Matsushita Electric........................         207
    17,000  Makita Corp.......................................         272
    66,000  Marubeni Corp.....................................         357
    20,000  Marui Co., Ltd....................................         416
    90,000  Matsushita Electric Industries Ltd................       1,464
    66,000  Mitsubishi Chemical Corp..........................         321
    62,000  Mitsubishi Corp...................................         763
    78,000  Mitsubishi Electric Corp..........................         561
    48,000  Mitsubishi Estate Co., Ltd........................         600
   121,000  Mitsubishi Heavy Industries Ltd...................         964
    45,000  Mitsubishi Materials Corp.........................         233
    43,000  Mitsubishi Trust & Banking Co.....................         716
    66,000  Mitsui & Co.......................................         579
   +44,000  Mitsui Engineering & Shipbuilding.................         122
    37,000  Mitsui Fudosan Co.................................         455
    25,000  Mitsukoshi Ltd....................................         235
     5,000  Mochida Pharmaceutical............................          69
    23,000  Murata Manufacturing Co., Ltd.....................         846
    91,000  NEC Corp..........................................       1,111
    44,000  New Oji Paper Co., Ltd............................         398
    22,000  NGK Insulators....................................         219
    22,000  Nippon Denso Co., Ltd.............................         411
    44,000  Nippon Express Co., Ltd...........................         424
    22,000  Nippon Fire & Marine Insurance Co.................         149
    22,000  Nippon Light Metal................................         126
    22,000  Nippon Meat Packers, Inc..........................         320
    66,000  Nippon Oil Co.....................................         414
   167,000  Nippon Steel Co...................................         573
    66,000  Nippon Yusen......................................         383
    84,000  Nissan Motor Co...................................         645
  +129,000  NKK Corp..........................................         347
    66,000  Nomura Securities Co..............................       1,438
    44,000  Odakyu Electric Railway...........................         300
    30,000  Olympus Optical Co., Ltd..........................         291
   133,000  Osaka Gas Co......................................         460
    22,000  Penta-Ocean Construction..........................         170
    18,000  Pioneer Electric Corp.............................         329
   111,000  Sakura Bank.......................................       1,408
    22,000  Sankyo Co., Ltd...................................         494
    66,000  Sanyo Electric Co., Ltd...........................         380
     5,000  Secom Co..........................................         348
     5,300  Sega Enterprises..................................         293
    22,000  Sekisui House Co., Ltd............................         281
    12,000  Seven-Eleven Japan................................         846
    73,000  Sharp Corp........................................       1,167
     6,000  Shimano, Inc......................................         106
    32,000  Shimizu Corp......................................         325
    10,000  Shin-Etsu Chemical Co.............................         207
    10,000  Shiseido Co., Ltd.................................         119
    27,000  Shizuoka Bank.....................................         340
   +44,000  Showa Denko.......................................         138
    17,000  Sony Corp.........................................       1,019
   111,000  Sumitomo Bank.....................................       2,354
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                             Active Country Allocation Portfolio
 
                                       7
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE ACTIVE COUNTRY ALLOCATION PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
  JAPAN (CONT.)
    23,000  Sumitomo Cement...................................  $      107
    89,000  Sumitomo Chemical Co..............................         444
    44,000  Sumitomo Corp.....................................         447
    30,000  Sumitomo Electric.................................         360
     9,000  Sumitomo Forestry Co., Ltd........................         138
   155,000  Sumitomo Metal Ind................................         470
    21,000  Sumitomo Metal & Mining...........................         189
    44,000  Taisei Corp., Ltd.................................         294
    44,000  Takeda Chemical...................................         724
     7,000  TDK Corp..........................................         357
    44,000  Teijin Ltd........................................         225
    44,000  Tobu Railway Co...................................         275
    21,925  Tohoku Electric Power.............................         529
    69,000  Tokai Bank........................................         962
    66,000  Tokio Marine & Fire Insurance Co..................         863
    10,000  Tokyo Dome Corp...................................         171
    43,952  Tokyo Electric Power Co...........................       1,175
     8,000  Tokyo Electron Ltd................................         310
   117,000  Tokyo Gas Co......................................         412
    44,000  Tokyu Corp........................................         311
    31,000  Toppan Printing Co., Ltd..........................         408
    66,000  Toray Industries, Inc.............................         435
    73,000  Toshiba Corp......................................         572
    22,000  Toto Ltd..........................................         307
    44,000  Toyoba Co.........................................         158
   103,000  Toyota Motor Corp.................................       2,185
   +44,000  Ube Industries Ltd................................         166
    44,000  Yamaichi Securities Co............................         342
    44,000  Yasuda Trust & Banking Co.........................         260
                                                                ----------
                                                                    71,490
                                                                ----------
  MALAYSIA (1.6%)
     5,000  AMMB Holdings Bhd.................................          57
    41,000  Amsteel Corp. Bhd.................................          30
     5,000  Aokam Perdana Bhd.................................           8
     6,000  Commerce Asset Holding Bhd........................          30
    20,000  DCB Holdings Bhd..................................          58
     6,000  Edaran Otomobil Nasional Bhd......................          45
    28,000  Golden Hope Plantations Bhd.......................          47
     5,000  Golden Plus Holdings Bhd..........................           9
    10,000  Guinness Anchor Bhd...............................          19
    19,000  Highlands & Lowlands Bhd..........................          31
     4,000  Hong Leong Industries Bhd.........................          21
    24,000  Hong Leong Properties Bhd.........................          25
     7,000  Hume Industries (Malaysia) Bhd....................          34
   +21,000  Idris Hydraulic (Malaysia) Bhd....................          25
    22,000  IGB Corp. Bhd.....................................          20
    28,000  IOI Corp. Bhd.....................................          27
    15,000  Kedah Cement Bhd..................................          26
     5,000  Kian Joo Can Factory Bhd..........................          21
    12,000  Land & General Bhd................................          26
    12,000  Leader Universal Holdings Bhd.....................          27
    28,000  Magnum Corp. Bhd..................................          53
    28,000  Malayan Banking Bhd...............................         236
    40,000  Malayan United Industries Bhd.....................          32
    18,000  Malaysian Airline System Bhd......................          58
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
    25,000  Malaysian International Shipping Bhd (Foreign)....  $       65
    15,000  Malaysian Mining Corp. Bhd........................          22
     3,000  Malaysian Oxygen Bhd..............................          11
    19,000  Malaysian Resources Corp. Bhd.....................          31
    26,000  Metroplex Bhd.....................................          21
    19,900  Mulpha International Bhd..........................          20
    20,000  Multi-Purpose Holdings Bhd........................          29
     4,000  Nestle (Malaysia) Bhd.............................          29
     5,000  Oriental Holdings Bhd.............................          25
     8,000  Perlis Plantations Bhd............................          25
     9,000  Petaling Garden Bhd...............................          10
    15,000  Proton............................................          53
    25,000  Public Bank Bhd...................................          48
    10,000  Rashid Hussain Bhd................................          30
    28,000  Resorts World Bhd.................................         150
     9,000  R.J. Reynolds Bhd.................................          21
     8,000  Rothmans of Pall Mall (Malaysia) Bhd..............          66
    11,000  Selangor Properties Bhd...........................          11
     8,000  Shell Refining Co. (Malaysia) Bhd.................          23
    53,000  Sime Darby Bhd....................................         141
    19,000  TA Enterprise Bhd.................................          23
    22,000  Tan Chong Motor Holdings Bhd......................          22
   +18,000  Technology Resources Industries Bhd...............          53
    51,000  Telekom Malaysia Bhd..............................         398
    79,700  Tenaga Nasional Bhd...............................         314
     9,000  UMW Holdings Bhd..................................          24
    16,000  United Engineers Ltd. (Malaysia)..................         102
    11,000  YTL Corp., Bhd....................................          69
                                                                ----------
                                                                     2,801
                                                                ----------
  NETHERLANDS (3.1%)
     7,469  ABN Amro Holdings N.V.............................         340
     1,850  Akzo Nobel N.V....................................         214
    15,600  Elsevier N.V......................................         208
       950  Heineken N.V......................................         169
     6,638  Internationale Nederlanden Groep N.V..............         444
     2,082  KLM Royal Dutch Airlines N.V......................          73
       750  Koninklijke Hoogovens N.V.........................          25
     3,074  Koninklijke Ahold N.V.............................         126
     2,500  Koninklijke KNP BT N.V............................          64
    21,194  Koninklijke PTT Nederland N.V.....................         770
       550  Nedlloyd Groep N.V................................          12
     7,900  Philips Electronics N.V...........................         286
    12,700  Royal Dutch Petroleum Co..........................       1,774
       700  Stork N.V.........................................          17
     3,800  Unilever N.V......................................         534
     1,650  Wolters Kluwer N.V................................         156
                                                                ----------
                                                                     5,212
                                                                ----------
  SINGAPORE (2.8%)
    23,000  Amcol Holdings Ltd................................          63
    62,000  City Developments Ltd.............................         451
    18,000  Cycle & Carriage Ltd..............................         179
    65,000  DBS Land Ltd......................................         220
    32,000  Development Bank of Singapore Ltd. (Foreign)......         398
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Active Country Allocation Portfolio
 
                                       8
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE ACTIVE COUNTRY ALLOCATION PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
  SINGAPORE (CONT.)
    16,000  First Capital Corp. Ltd...........................  $       44
    19,000  Fraser & Neave Ltd................................         242
    25,000  Hai Sun Hup Group Ltd.............................          17
    33,000  Hotel Properties Ltd..............................          51
    15,000  Inchcape Bhd......................................          48
     9,000  Jurong Shipyard Ltd...............................          69
    40,000  Keppel Corp., Ltd.................................         356
    22,000  Natsteel Ltd......................................          45
    63,000  Neptune Orient Lines Ltd..........................          71
    47,000  Oversea-Chinese Banking Corp. (Foreign)...........         588
    12,000  Overseas Union Enterprise Ltd.....................          61
    25,000  Parkway Holdings Ltd..............................          68
     4,000  Robinson & Co. Ltd................................          17
    13,000  Shangri-La Hotel Ltd..............................          51
    59,000  Singapore Airlines Ltd. (Foreign).................         551
    16,800  Singapore Press Holdings (Foreign)................         297
    47,000  Straits Steamship Land Ltd........................         159
    31,000  Straits Trading Co., Ltd..........................          73
   125,000  United Industrial Corp. Ltd.......................         123
    49,000  United Overseas Bank Ltd. (Foreign)...............         471
                                                                ----------
                                                                     4,713
                                                                ----------
  SPAIN (2.5%)
       610  Acerinox S.A......................................          62
     5,800  Argentaria S.A....................................         239
    10,233  Autopistas (ACESA)................................         116
    10,900  Banco Bilbao Vizcaya S.A..........................         393
     7,300  Banco Central Hispano Americano S.A...............         148
     5,500  Banco de Santander S.A............................         276
     1,000  Corporacion Financiera Alba.......................          62
     1,300  Corporacion Mapfre................................          73
     3,300  Dragados y Construccion S.A.......................          43
     2,700  Ebro Agricolas S.A................................          28
     1,000  ENCE S.A..........................................          16
    12,200  Endesa S.A........................................         691
    +4,900  Ercros S.A........................................           3
     1,100  FASA Renault S.A..................................          18
       700  Fomento Construction y Contractas S.A.............          54
     1,750  Gas Natural SDG S.A...............................         273
    42,100  Iberdrola S.A.....................................         385
       200  MetroVacesa.......................................           7
       500  Portland Valderrivas S.A..........................          32
    14,100  Repsol S.A........................................         462
     1,800  Tabacalera S.A., Class A..........................          68
    44,200  Telefonica de Espana S.A..........................         612
    14,700  Union Electrica Fenosa S.A........................          88
     1,950  Uralita S.A.......................................          18
     2,100  Vallehermoso S.A..................................          39
     1,200  Viscofan Envolturas Celulosicas S.A...............          14
       390  Zardoya Otis S.A..................................          43
                                                                ----------
                                                                     4,263
                                                                ----------
  SWITZERLAND (3.3%)
       +75  Adia S.A.(Bearer).................................          12
        50  Alusuisse-Lonza Holdings Ltd. (Bearer)............          40
       100  Alusuisse-Lonza Holdings Ltd. (Registered)........          79
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
       165  BBC Brown Boveri AG (Bearer)......................  $      192
        90  Ciba-Geigy AG (Bearer)............................          79
       450  Ciba-Geigy AG (Registered)........................         396
     2,275  CS Holding AG (Registered)........................         233
        10  Georg Fischer AG (Bearer).........................          13
       135  Holderbank AG (Bearer)............................         104
       100  Merkur Holding AG (Registered)....................          22
       710  Nestle S.A. (Registered)..........................         785
        30  Roche Holding AG (Bearer).........................         420
       130  Roche Holding AG (Registered).....................       1,028
       630  Sandoz AG (Registered)............................         577
        35  SGS Surveillance (Bearer).........................          69
        70  SMH AG (Bearer)...................................          42
       300  SMH AG (Registered)...............................          39
        70  Sulzer AG (Registered)............................          40
       +50  SwissAir (Registered).............................          36
       450  Swiss Bank Corp. (Bearer).........................         184
       700  Swiss Bank Corp. (Registered).....................         143
       300  Swiss Reinsurance (Registered)....................         349
       390  Union Bank of Switzerland (Bearer)................         423
       430  Union Bank of Switzerland (Registered)............          98
       500  Zuerich Versicherung (Registered).................         149
                                                                ----------
                                                                     5,552
                                                                ----------
  THAILAND (2.6%)
    21,500  Advanced Information Services Co., Ltd.
              (Foreign).......................................         381
   +32,400  Bangchak Petroleum Co., Ltd. (Foreign)............          68
  +107,300  Bangkok Metropolitan Bank Ltd.....................         102
    11,900  Bank of Ayudhya Ltd. (Foreign)....................          67
    11,800  CMIC Finance & Securities Co., Ltd................          39
     3,600  CP Feedmill Co., Ltd. (Foreign)...................          18
    23,200  Dhana Siam Finance & Securities Co., Ltd..........         133
    27,400  General Finance & Securities Co., Ltd.
              (Foreign).......................................         126
    22,900  Italian Thai Development Co., Ltd. (Foreign)......         260
    20,700  Jasmine International Co., Ltd. (Foreign).........         127
   127,500  Krung Thai Bank Ltd. (Foreign)....................         526
    19,600  National Finance & Securities Co. Ltd.
              (Foreign).......................................         105
    19,200  National Petrochemical............................          49
    +9,900  One Holding Co., Ltd. (Foreign)...................          25
    16,900  Phatra Thanakit Co., Ltd. (Foreign)...............         145
   +28,400  PTT Exploration & Production Co., Ltd (Foreign)...         298
   +23,000  Quality House Public..............................         100
   +46,900  Sahaviriya Steel Industry (Foreign)...............          62
    12,700  Shinawatra Computer Co., Ltd (Foreign)............         313
   +21,700  Shinawatra Satellite Co., Ltd. (Foreign)..........          35
     3,600  Siam Cement Co., Ltd. (Foreign)...................         200
    74,600  Siam City Bank Ltd. (Foreign).....................          86
     3,500  Siam City Cement Co., Ltd. (Foreign)..............          55
  +204,100  TelecomAsia Corp., Ltd. (Foreign).................         624
    41,600  Thai Airways International Co., Ltd. (Foreign)....          78
    26,500  Thai Military Bank Ltd. (Foreign).................         107
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                             Active Country Allocation Portfolio
 
                                       9
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE ACTIVE COUNTRY ALLOCATION PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
  THAILAND (CONT.)
    21,500  United Communications Industry (Foreign)..........  $      275
                                                                ----------
                                                                     4,404
                                                                ----------
  UNITED KINGDOM (7.9%)
    30,600  Abbey National plc................................         302
    22,900  Argyll Group plc..................................         121
    22,200  Arjo Wiggins Appleton plc.........................          57
    15,600  Associated British Foods plc......................          89
    26,300  Barclays plc......................................         302
    16,600  Bass plc..........................................         185
    55,823  BAT Industries plc................................         492
    10,500  BICC plc..........................................          45
    19,400  Blue Circle Industries plc........................         103
     9,500  BOC Group plc.....................................         133
    19,400  Boots Co. plc.....................................         176
    13,100  BPB Industries plc................................          61
     7,800  British Aerospace plc.............................          97
    18,100  British Airways plc...............................         131
    81,900  British Gas plc...................................         323
    93,400  British Petroleum Co. plc.........................         782
    32,100  British Sky Broadcasting plc......................         203
    33,900  British Steel plc.................................          86
    84,900  British Telecommunications plc....................         467
    65,700  BTR plc...........................................         336
     4,484  Burmah Castrol plc................................          65
    39,403  Cable & Wireless plc..............................         281
    18,700  Cadbury Schweppes plc.............................         154
    12,200  Caradon plc.......................................          37
    13,300  Coats Viyella plc.................................          36
     8,000  Commercial Union plc..............................          78
     7,800  Courtaulds plc....................................          49
     5,578  De La Rue Co. plc.................................          56
    26,200  Forte plc.........................................         134
     7,800  General Accident plc..............................          79
    59,400  General Electric plc..............................         327
     8,300  GKN plc...........................................         100
    54,500  Glaxo Wellcome plc................................         774
    43,772  Grand Metropolitan plc............................         315
    18,900  Great Universal Stores plc........................         201
    25,869  Guardian Royal Exchange plc.......................         111
    32,200  Guinness plc......................................         237
    93,700  Hanson plc........................................         280
    18,900  Harrisons & Crosfields plc........................          47
    36,600  HSBC Holdings plc.................................         558
    13,300  Imperial Chemical Industries plc..................         157
    26,100  Ladbroke Group plc................................          59
    11,600  Land Securities plc...............................         111
    16,600  Lasmo plc.........................................          45
    58,947  Lloyds TSB Group plc..............................         303
    13,862  Lonrho plc........................................          38
    53,800  Marks and Spencer plc.............................         376
     8,900  MEPC plc..........................................          55
    22,100  National Power plc................................         154
    10,000  North West Water Group plc........................          96
    16,100  Peninsular & Oriental Steam Navigation Co.........         119
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
    22,200  Pilkington plc....................................  $       70
    39,100  Prudential Corp. plc..............................         252
     8,300  Rank Organization plc.............................          60
    12,200  Redland plc.......................................          74
    10,500  Reed International plc............................         160
    29,200  Reuters Holdings plc..............................         267
     8,900  Rexam plc.........................................          49
     7,100  RMC Group plc.....................................         109
    14,400  Royal Bank of Scotland Group plc..................         131
    13,100  Royal Insurance Holdings plc......................          78
    22,700  RTZ Corp. plc.....................................         330
    22,560  Sainsbury (J) plc.................................         138
     4,500  Schroders plc.....................................          96
    14,000  Scottish Power plc................................          80
    28,800  Sears plc.........................................          47
     9,000  Sedgwick Group plc................................          17
     6,700  Slough Estates plc................................          23
    22,600  SmithKline Beecham plc, Class A...................         249
     5,600  Southern Electric plc.............................          79
    20,600  Tarmac plc........................................          33
    11,100  Taylor Woodrow plc................................          20
    29,300  Tesco plc.........................................         135
    10,500  Thames Water plc..................................          92
     9,400  THORN EMI plc.....................................         221
     7,800  TI Group plc......................................          56
   +20,000  Trafalgar House plc...............................           9
    11,900  Unilever plc......................................         244
    55,700  Vodafone Group plc................................         199
    13,500  Zeneca Group plc..................................         261
                                                                ----------
                                                                    13,502
                                                                ----------
TOTAL COMMON STOCKS (Cost $142,163)...........................     152,786
                                                                ----------
PREFERRED STOCKS (2.0%)
  AUSTRALIA (0.1%)
    24,000  News Corp., Ltd...................................         112
                                                                ----------
  BRAZIL (NON-VOTING STOCKS) (1.7%)
    31,666  Aracruz Celelose S.A., Class B....................          49
19,080,443  Banco Bradesco....................................         167
+4,252,000  Banco do Brasil...................................          48
+1,871,000  Banco do Estado Sao Paulo.........................          10
   249,663  Brahma............................................         103
 1,191,000  Ceval Alimentos S.A...............................          14
 1,786,000  Cia Brasileira de Petroleo Ipiranga...............          15
 4,035,500  Cia Energetica de Minas Gerais....................          89
  +102,000  Cia Energetica de Sao Paulo.......................           3
 3,570,000  Cia Siderurgica de Tubarao........................          58
 2,636,000  Eletrobras, Class B...............................         713
    32,500  Industrias Klabin de Papel e Celulose S.A.........          29
   111,000  Investimentos Itau S.A............................          61
   357,000  Itaubanco.........................................         100
 3,742,000  Petrobras.........................................         320
    27,000  Sadia Concordia...................................          20
12,416,000  Telebras..........................................         598
   638,000  Telecomunicacoes de Sao Paulo.....................          94
56,980,000  Usiminas..........................................          46
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Active Country Allocation Portfolio
 
                                       10
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE ACTIVE COUNTRY ALLOCATION PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
  BRAZIL (CONT.)
 1,956,000  Vale Do Rio Doce..................................  $      322
                                                                ----------
                                                                     2,859
                                                                ----------
  GERMANY (0.2%)
       500  RWE AG............................................         139
     1,050  SAP AG............................................         159
                                                                ----------
                                                                       298
                                                                ----------
  ITALY (0.0%)
    27,000  Fiat S.p.A........................................          49
                                                                ----------
TOTAL PREFERRED STOCKS (Cost $3,082)..........................       3,318
                                                                ----------
  NO. OF
  RIGHTS
- ----------
RIGHTS (0.0%)
  BRAZIL (0.0%)
+**446,139  Banco Bradesco, expiring 2/96.....................           1
                                                                ----------
  SPAIN (0.0%)
  +**4,900  Ercros, expiring 1/5/96...........................          --
                                                                ----------
  UNITED KINGDOM (0.0%)
    +7,425  Pilkington plc, expiring 1/8/96...................          23
                                                                ----------
TOTAL RIGHTS (Cost $18).......................................          24
                                                                ----------
  NO. OF
 WARRANTS
- ----------
WARRANTS (0.0%)
  BELGIUM (0.0%)
      +347  Petrofina S.A., expiring 6/03/97..................           5
                                                                ----------
  HONG KONG (0.0%)
  +**4,400  Applied International Holdings, expiring
              12/30/99........................................          --
                                                                ----------
  ITALY (0.0%)
    +2,950  R.A.S. S.p.A, expiring 12/31/97...................          12
    +1,550  R.A.S. S.p.A., Saving Shares, expiring 12/31/97...           3
                                                                ----------
                                                                        15
                                                                ----------
  MALAYSIA (0.0%)
  **+2,400  Hong Leong Properties, expiring 10/00.............          --
 +***7,000  IOI Corp..........................................           1
                                                                ----------
  THAILAND (0.0%)
  +**3,050  CMIC Finance & Securities Co., Ltd., expiring
              1999............................................           1
  +**6,400  National Finance & Securities Co. Ltd. expiring
              11/15/99........................................          --
                                                                ----------
                                                                         1
                                                                ----------
  UNITED KINGDOM (0.0%)
      +534  British Aerospace, expiring 11/15/00..............           3
                                                                ----------
TOTAL WARRANTS (Cost $1)......................................          25
                                                                ----------
 
  NO. OF                                                          VALUE
  UNITS                                                           (000)
- ------------------------------------------------------------
UNITS (0.2%)
  AUSTRALIA (0.0%)
    20,821  General Property Trust............................  $       37
    22,888  Westfield Trust...................................          41
     1,762  Westfield Trust (New).............................           3
                                                                ----------
                                                                        81
                                                                ----------
  UNITED KINGDOM (0.2%)
    21,700  SmithKline Beecham plc............................         237
                                                                ----------
TOTAL UNITS (Cost $270).......................................         318
                                                                ----------
   FACE
  AMOUNT
  (000)
- ----------
CONVERTIBLE DEBENTURES (0.0%)
  FRANCE (0.0%)
 FRF    60  Sanofi 4.00%, 1/1/00..............................          45
                                                                ----------
  ITALY (0.0%)
ITL  3,150  Saffa S.p.A. 9.25%, 1/1/01........................           2
                                                                ----------
TOTAL CONVERTIBLE DEBENTURES (Cost $40).......................          47
                                                                ----------
TOTAL FOREIGN SECURITIES (91.7%)
(Cost $145,574)...............................................     156,518
                                                                ----------
SHORT-TERM INVESTMENT (2.2%)
  UNITED STATES (2.2%)
  REPURCHASE AGREEMENT (2.2%)
$    3,746  The Chase Manhattan Bank, N.A., 5.35%, dated
              12/29/95, due 1/02/96, to be repurchased at
              $3,748, collateralized by $3,045 United States
              Treasury Bonds, 7.875%, due 2/15/21, valued at
              $3,821 (Cost $3,746)............................       3,746
                                                                ----------
FOREIGN CURRENCY (0.2%)
  AUD   14  Australian Dollar.................................          10
 BEF   623  Belgian Franc.....................................          21
 GBP    17  British Pound.....................................          26
  DEM   17  Deutsche Mark.....................................          12
 FRF    61  French Franc......................................          12
  HKD  383  Hong Kong Dollar..................................          50
IDR  2,251  Indonesian Rupiah.................................           1
JPY  4,508  Japanese Yen......................................          44
  MYR   16  Malaysian Ringgit.................................           6
 NLG    68  Netherlands Guilder...............................          43
PTE 20,102  Portuguese Escudo.................................         134
 SGD    31  Singapore Dollar..................................          22
 ESP   195  Spanish Peseta....................................           2
 CHF     3  Swiss Franc.......................................           3
 THB   162  Thai Baht.........................................           6
                                                                ----------
TOTAL FOREIGN CURRENCY (Cost $391)............................         392
                                                                ----------
TOTAL INVESTMENTS (94.1%) (Cost $149,711).....................     160,656
                                                                ----------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                             Active Country Allocation Portfolio
 
                                       11
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE ACTIVE COUNTRY ALLOCATION PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
 
                                             AMOUNT
                                             (000)
- ----------------------------------------------------
OTHER ASSETS (6.0%)
  Net Unrealized Gain on
   Forward Foreign Currency
   Exchange Contracts.........  $    9,417
  Receivable for Portfolio
   Shares Sold................         524
  Foreign Withholding Tax
   Reclaim Receivable.........         167
  Dividends Receivable........         164
  Interest Receivable.........           2
  Other.......................          14  $ 10,288
                                ----------
LIABILITIES (-0.1%)
  Investment Advisory Fees
   Payable....................         (77)
  Custodian Fees Payable......         (71)
  Payable for Portfolio Shares
   Redeemed...................         (43)
  Administrative Fees
   Payable....................         (26)
  Payable for Investments
   Purchased..................         (23)
  Other Liabilties............         (41)     (281)
                                ----------  --------
NET ASSETS (100%).........................  $170,663
                                            --------
                                            --------
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 14,672,976 outstanding
  $.001 par value shares (authorized
  500,000,000 shares).....................    $11.63
                                            --------
                                            --------
 
 FORWARD FOREIGN CURRENCY EXCHANGE CONTRACT
 INFORMATION:
  Under the terms of forward foreign currency
  exchange contracts open at December 31, 1995, the
  Portfolio is obligated to deliver or is to receive
  foreign currency in exchange for U.S. dollars as
  indicated below:
 
<TABLE>
<CAPTION>
                                                                NET
                                                              UNREALIZED
 CURRENCY TO                          IN EXCHANGE               GAIN
   DELIVER      VALUE    SETTLEMENT       FOR        VALUE     (LOSS)
    (000)       (000)       DATE         (000)       (000)     (000)
- -------------  --------  ----------  -------------  --------  --------
<S>            <C>       <C>         <C>            <C>       <C>
   DEM  5,930  $  4,136    1/04/96   U.S.$   4,155  $  4,155  $    19
  FRF  28,174     5,753    1/04/96   U.S.$   5,670     5,670      (83)
   CHF  6,170     5,382    2/28/96   U.S.$   5,100     5,100     (282)
  BEF 225,256     7,669    4/30/96   U.S.$   8,000     8,000      331
   DEM  6,458     4,525    4/30/96   U.S.$   4,500     4,500      (25)
 JPY4,591,639    45,210    4/30/96   U.S.$  54,440    54,440    9,230
 U.S.$  4,790     4,790    4/30/96     BEF 141,479     4,817       27
 U.S.$  7,378     7,378    4/30/96     JPY 606,988     5,977   (1,401)
   NLG 12,205     7,686    7/31/96   U.S.$   8,000     8,000      314
 U.S.$  2,850     2,850    7/31/96       NLG 4,661     2,935       85
  JPY 886,827     8,849    8/14/96   U.S.$   9,630     9,630      781
  JPY 310,447     3,104    8/30/96   U.S.$   3,525     3,525      421
               --------                             --------  --------
               $107,332                             $116,749  $ 9,417
               --------                             --------  --------
               --------                             --------  --------
</TABLE>
 
- ------------------------------------------------------------
 
+        --   Non-income producing security
**       --   Security is valued at fair
              value -- See Note A-1
***      --   Security is valued at cost --
              See Note A-1
NCS      --   Non Convertible Shares
RFD      --   Ranked for Dividends
ITL      --   Italian Lira
 
- ------------------------------------------------
 
            SUMMARY OF FOREIGN SECURITIES BY INDUSTRY CLASSIFICATION
                                  (UNAUDITED)
 
                                  VALUE      PERCENT OF
INDUSTRY                          (000)      NET ASSETS
- --------------------------------------------------------
Capital Equipment.............  $   21,419         12.6%
Consumer Goods................      27,288         16.0
Energy........................      16,779          9.8
Finance.......................      43,246         25.3
Gold Mines....................          72           --
Materials.....................      18,501         10.8
Multi-Industry................       7,106          4.2
Services......................      22,107         13.0
                                ----------          ---
                                $  156,518         91.7%
                                ----------          ---
                                ----------          ---
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Active Country Allocation Portfolio
 
                                       12
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE ASIAN EQUITY PORTFOLIO
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                    VALUE
   SHARES                                                           (000)
- ------------------------------------------------------------
<C>           <S>                                                 <C>
COMMON STOCKS (91.0%)
  CHINA (1.2%)
     979,440  China Merchants Shekou Port Services, Class B.....  $      355
     +28,200  Jilin Chemical Co. Ltd. ADR.......................         606
   5,505,000  Maanshan Iron & Steel Co., Class H................         769
      51,000  Shandong Huaneng Power Co., Ltd. ADR..............         344
   1,601,600  Shanghai Jinqiao, Class B.........................         599
    +555,400  Shanghai Refrigerator Compressor, Class B.........         198
     276,000  Shanghai Tyre & Rubber Co., Class B...............          57
   4,265,000  Yizheng Chemical Fibre Co., Class H...............         960
                                                                  ----------
                                                                       3,888
                                                                  ----------
  HONG KONG (26.7%)
   2,316,000  Cheung Kong Holdings Ltd..........................      14,107
     358,000  China Light & Power Co., Ltd......................       1,648
   1,209,500  Citic Pacific Ltd.................................       4,137
   6,294,000  C.P. Pokphand Co., Ltd............................       2,523
  11,712,000  Guangdong Investments Ltd.........................       7,043
   1,056,000  Harbin Power Equipment Co.........................         155
     765,500  Hong Kong Electric Holdings Ltd...................       2,510
     673,320  Hong Kong & Shanghai Bank Holdings plc............      10,188
   5,088,600  Hong Kong Telecommunications Ltd..................       9,081
   3,812,000  Hopewell Holdings Ltd.............................       2,194
   1,827,000  Hutchison Whampoa Ltd.............................      11,129
  +1,605,000  New World Development Co., Ltd....................       6,995
       3,008  New World Infrastructure Ltd......................           6
  +1,835,100  Shenzen North Jainshe Motorcycle Co., Ltd., Class
                B...............................................         759
     612,100  Sun Hung Kai Properties Ltd.......................       5,007
     621,560  Swire Pacific Ltd., Class A.......................       4,823
     906,000  Varitronix International Ltd......................       1,681
                                                                  ----------
                                                                      83,986
                                                                  ----------
  INDIA (0.8%)
      38,000  Grasim Industries Ltd. GDR........................         779
     #51,000  Hindalco Industries Ltd. GDR......................       1,734
                                                                  ----------
                                                                       2,513
                                                                  ----------
  INDONESIA (5.3%)
   **583,000  Asiana Imi Industries (Foreign)...................         306
   **294,000  Bank Bali (Foreign)...............................         579
   **859,000  Barito Pacific Timber (Foreign)...................         629
  +**691,000  Bimantara Citra (Foreign).........................         574
   **621,826  Charoen Pokphand (Foreign)........................       1,265
   **141,100  Hanajaya Mandala Sampoerna (Foreign)..............       1,469
   **302,000  Indocement Tunggal (Foreign)......................       1,013
   **730,000  Indosat (Foreign).................................       2,650
   **351,600  Kalbe Farma (Foreign).............................       1,192
   **210,000  Keramika Indonesia Assosiasi (Foreign)............         101
 **1,400,000  Ometraco (Foreign)................................         689
  +**177,000  Polysindo Eka Perkasa (Foreign)...................         101
   **315,000  Semen Gresik (Foreign)............................         882
 **2,750,400  Sona Topas Tourism (Foreign)......................         782
 
<CAPTION>
                                                                    VALUE
   SHARES                                                           (000)
- ------------------------------------------------------------
<C>           <S>                                                 <C>
   **277,333  Sorini Corp. (Foreign)............................  $    1,345
   **210,500  Suba Indah (Foreign)..............................         140
+**1,170,500  Telekomunikasi Indonesia (Foreign)................       1,536
   **590,000  Ultra Jaya Milk (Foreign).........................         284
   **644,800  United Tractors (Foreign).........................       1,213
                                                                  ----------
                                                                      16,750
                                                                  ----------
  KOREA (3.3%)
    **53,900  Korea Electric Power (Foreign)....................       2,311
     **1,500  Korea Mobile Telecom (Foreign)....................       1,657
      61,600  Pohang Iron & Steel Co., Ltd. ADR.................       1,348
     +21,953  Samsung Electronics (Foreign).....................       3,990
        +185  Samsung Electronics (Foreign) (New)...............          34
         +44  Samsung Electronics GDR...........................           3
       +#152  Samsung Electronics GDS...........................          15
       +#771  Samsung Electronics GDS (Voting Shares)...........          74
        +811  Samsung Electronics RFD (New).....................         145
    **44,460  Shinhan Bank (Foreign)............................         976
                                                                  ----------
                                                                      10,553
                                                                  ----------
  MALAYSIA (19.3%)
     149,000  AMMB Holdings Bhd.................................       1,701
     604,000  Bandar Raya Developments Bhd......................         861
     954,500  Genting Bhd.......................................       7,968
     861,000  Land & General Holdings Bhd.......................       1,865
     714,000  Magnum Corp. Bhd..................................       1,349
   1,191,500  Malayan Banking Bhd...............................      10,040
   1,125,316  Malaysian International Shipping Bhd (Foreign)....       2,947
       1,000  Malaysian Resources Corp. Bhd.....................           2
     518,000  Petronas Gas Bhd..................................       1,764
   2,528,000  Renong Bhd........................................       3,743
   1,388,000  Resorts World Bhd.................................       7,433
     650,000  Sime Darby Bhd....................................       1,727
   1,243,000  Tan & Tan Development Bhd.........................       1,062
    +569,000  Technology Resources Industries Bhd...............       1,680
     785,000  Telekom Malaysia Bhd..............................       6,120
   1,314,000  Tenaga Nasional Bhd...............................       5,173
     264,000  Time Engineering Bhd..............................         613
     718,757  United Engineers Ltd. (Malaysia)..................       4,585
                                                                  ----------
                                                                      60,633
                                                                  ----------
  PHILIPPINES (5.6%)
   1,379,300  Ayala Corp., Class B..............................       1,683
   1,175,625  Ayala Land, Inc., Class B.........................       1,434
  +2,062,100  C&P Homes, Inc....................................       1,513
  +1,791,000  DMCI Holdings, Inc................................         642
    +597,700  Fil-Estate Land Inc...............................         450
   6,958,000  JG Summit Holding, Class B........................       1,910
     362,050  Manila Electric Co., Class B......................       2,954
   5,149,900  Petron Corp.......................................       2,651
      18,125  Phillipine Long Distance Telephone Co., ADR.......         981
      15,430  Philippine Long Distance Telephone Co., Class B...         838
     +29,440  Philippine National Bank, Class B.................         326
     317,200  San Miguel Corp., Class B.........................       1,082
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
- --------------------------------------------------------------------------------
                                                          Asian Equity Portfolio
 
                                       15
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE ASIAN EQUITY PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                    VALUE
   SHARES                                                           (000)
- ------------------------------------------------------------
<C>           <S>                                                 <C>
  PHILIPPINES (CONT.)
  +4,508,000  SM Prime Holdings, Inc., Class B..................  $    1,289
                                                                  ----------
                                                                      17,753
                                                                  ----------
  SINGAPORE (13.1%)
     206,000  British-American Tobacco Co.......................         794
     628,080  City Developments Ltd.............................       4,574
     912,000  DBS Land Ltd......................................       3,082
     362,500  Development Bank of Singapore Ltd. (Foreign)......       4,510
     148,800  Fraser & Neave Ltd................................       1,894
     690,000  Keppel Corp., Ltd.................................       6,146
     538,166  Oversea-Chinese Banking Corp. (Foreign)...........       6,734
     263,000  Sembawang Corp....................................       1,460
     111,000  Singapore Airlines Ltd. (Foreign).................       1,035
      89,400  Singapore Press Holdings (Foreign)................       1,580
   1,472,000  Singapore Technologies Industrial Corp............       3,330
     507,000  Straits Steamship Land Ltd........................       1,713
     500,000  Straits Trading Co., Ltd..........................       1,174
     332,200  United Overseas Bank Ltd. (Foreign)...............       3,194
                                                                  ----------
                                                                      41,220
                                                                  ----------
  TAIWAN (2.5%)
     806,000  Acer, Inc.........................................       1,861
     412,000  Advanced Semiconductor Engineering, Inc...........         997
     904,000  Taiwan Semiconductor Manufacturing Co.............       2,832
     905,000  United Micro Electronics Corp., Ltd...............       2,272
                                                                  ----------
                                                                       7,962
                                                                  ----------
  THAILAND (13.2%)
      84,000  Advanced Information Services Co., Ltd.
                (Foreign).......................................       1,487
     583,200  Bangkok Bank Ltd. (Foreign).......................       7,085
     679,900  Finance One Co., Ltd. (Foreign)...................       4,723
      36,000  Land & House Co., Ltd. (Foreign)..................         592
    +202,800  National Finance & Securities Co., Ltd.
                (Foreign).......................................       1,087
     266,600  Phatra Thanakit Co., Ltd. (Foreign)...............       2,286
      84,100  Shinawatra Computer Co., Ltd (Foreign)............       2,070
      38,900  Siam Cement Co., Ltd. (Foreign)...................       2,157
     344,100  Siam Commercial Bank (Foreign)....................       4,535
  +1,450,500  TelecomAsia Corp. (Foreign).......................       4,434
     702,170  Thai Farmers Bank Ltd. (Foreign)..................       7,080
    +320,000  Thai Telephone & Telecom (Foreign)................       2,298
     101,000  United Communications Industry (Foreign)..........       1,291
     375,000  Wongpaitoon Footware Co., Ltd. (Foreign)..........         406
                                                                  ----------
                                                                      41,531
                                                                  ----------
TOTAL COMMON STOCKS (Cost $243,859).............................     286,789
                                                                  ----------
<CAPTION>
 
   NO. OF                                                           VALUE
  WARRANTS                                                          (000)
</TABLE>
 
- ------------------------------------------------------------
<TABLE>
<C>           <S>                                                 <C>
WARRANTS (0.0%)
  INDONESIA (0.0%)
  **+150,000  Ometraco, expiring 7/12/00 (Cost $0)..............  $       --
                                                                  ----------
TOTAL FOREIGN SECURITIES (91.0%) (Cost $243,859)................     286,789
                                                                  ----------
 
<CAPTION>
FACE AMOUNT
   (000)
- ------------
SHORT-TERM INVESTMENT (8.3%)
  UNITED STATES
  REPURCHASE AGREEMENT (8.3%)
$     26,154  The Chase Manhattan Bank, N.A. 5.35%, dated
                12/29/95 due 1/02/96, to be repurchased at
                $26,170, collateralized by $16,885 United States
                Treasury Bonds, 12.00%, due 8/15/13, valued at
                $26,678 (Cost $26,154)..........................      26,154
                                                                  ----------
FOREIGN CURRENCY (0.3%)
   HKD 2,770  Hong Kong Dollar..................................         358
 IDR 810,970  Indonesian Rupiah.................................         355
   MYR     1  Malaysian Ringgit.................................          --
   TWD 3,102  Taiwan Dollar.....................................         114
                                                                  ----------
TOTAL FOREIGN CURRENCY (Cost $827)..............................         827
                                                                  ----------
TOTAL INVESTMENTS (99.6%) (Cost $270,840).......................     313,770
                                                                  ----------
</TABLE>
 
<TABLE>
<S>                                                 <C>         <C>
OTHER ASSETS (1.2%)
  Receivable for Investments Sold.................  $    2,182
  Receivable for Portfolio Shares Sold............       1,007
  Dividends Receivable............................         472
  Foreign Withholding Tax Reclaim Receivable......          23
  Interest Receivable.............................          12
  Other...........................................          23       3,719
                                                    ----------
LIABILITIES (-0.8%)
  Payable for Portfolio Shares Redeemed...........      (1,025)
  Bank Overdraft..................................        (541)
  Payable for Investments Purchased...............        (427)
  Investment Advisory Fees Payable................        (411)
  Custodian Fees Payable..........................        (112)
  Administrative Fees Payable.....................         (41)
  Other Liabilities...............................         (48)     (2,605)
                                                    ----------  ----------
NET ASSETS (100%).............................................  $  314,884
                                                                ----------
                                                                ----------
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 16,166,258 outstanding $.001 par value shares
  (authorized 500,000,000 shares).............................      $19.48
                                                                ----------
                                                                ----------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
- --------------------------------------------------------------------------------
Asian Equity Portfolio
 
                                       16
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE ASIAN EQUITY PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
 
- ------------------------------------------------------------
 
<TABLE>
<S>        <C>        <C>
+             --      Non-income producing security
**            --      Securities (totaling $21,694 or 6.9% of net assets
                      at December 31, 1995) valued at fair value -- See
                      Note A-1
#             --      144A Security -- Certain conditions for public sale
                      may exist.
ADR           --      American Depositary Receipt
GDR           --      Global Depositary Receipt
GDS           --      Global Depositary Shares
RFD           --      Ranked for Dividends
</TABLE>
 
- ------------------------------------------------------------
 
            SUMMARY OF FOREIGN SECURITIES BY INDUSTRY CLASSIFICATION
                                  (UNAUDITED)
 
<TABLE>
<CAPTION>
                                         VALUE     PERCENT OF
INDUSTRY                                 (000)     NET ASSETS
<S>                                    <C>        <C>
- ---------------------------------------------------------------
Capital Equipment....................  $  27,807         8.8%
Consumer Goods.......................     18,705         5.9
Energy...............................     19,356         6.2
Finance..............................    118,063        37.5
Materials............................     12,063         3.8
Multi-Industry.......................     25,827         8.2
Services.............................     64,968        20.6
                                       ---------     -----
                                       $ 286,789        91.0%
                                       ---------     -----
                                       ---------     -----
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
- --------------------------------------------------------------------------------
                                                          Asian Equity Portfolio

                                       17
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE EMERGING MARKETS PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                    VALUE
    SHARES                                                          (000)
- ------------------------------------------------------------
<C>              <S>                                               <C>
COMMON STOCKS (84.1%)
  ARGENTINA (1.0%)
             +6  Acindar Industrial S.A., Class B................  $     --
       #120,670  Capex S.A. ADR..................................     1,765
         67,858  Capex S.A., Class A.............................       495
        431,533  Quilmes Industrial S.A..........................     6,732
                                                                   --------
                                                                      8,992
                                                                   --------
  BRAZIL (5.6%)
    302,170,000  Cia Acos Especiais Itabira......................     1,430
       +124,935  Cia Brasileira ADR..............................     1,249
           #696  Cia Energetica de Minas Gerais ADR..............        15
         84,361  Cia Energetica de Minas Gerais GDR..............     1,867
  #+116,352,140  Cia Energetica de Sao Paulo.....................     2,634
     49,544,000  Cia Paulista de Forca E Luz.....................     2,401
     17,175,000  Eletrobras......................................     4,648
       #180,024  Rhodia-Ster ADS.................................     1,620
      7,175,000  Servicos de Eletricidade........................     2,296
    139,692,000  Telebras........................................     5,404
       #512,169  Telebras ADR....................................    24,264
      5,175,000  Telecomunicacoes de Sao Paulo...................       748
            #50  Usiminas ADR....................................         1
                                                                   --------
                                                                     48,577
                                                                   --------
  CHINA (1.6%)
        750,000  Beiren Printing Machine, Class H................       136
      3,340,040  China Merchants Shekou Port Services, Class B...     1,209
      3,720,000  Harbin Power Equipment Co. Ltd., Class H........       548
        +91,500  Jilin Chemical Co. Ltd. ADR.....................     1,967
      2,658,500  Shanghai Diesel Engine Co., Ltd., Class B.......       984
       +883,300  Shanghai Erfanji Co., Ltd., Class B.............       125
        949,975  Shanghai Jin Jiang Tower Ltd., Class B..........       268
      3,673,680  Shanghai Jinqiao, Class B.......................     1,374
      1,062,750  Shanghai Outer Gaoqiao Free Zone, Class B.......       389
        903,800  Shanghai Phoenix Bicycle Ltd., Class B..........       150
     +1,114,130  Shanghai Refrigerator Compressor, Class B.......       397
        986,000  Shanghai Tyre & Rubber Co., Class B.............       203
        354,000  Shanghai Yaohua Pilkington Glass, Class B.......       312
      3,126,400  Shenzhen Chiwan Wharf Holdings, Class B.........     1,177
     +4,171,000  Shenzhen North Jianshe Motorcycle Co., Ltd.,
                   Class B.......................................     1,726
     13,658,000  Yizheng Chemical Fibre Co., Class H.............     3,073
         68,000  Zhuhai Lizhu Pharmaceutical Group, Inc., Class
                   B.............................................        22
                                                                   --------
                                                                     14,060
                                                                   --------
 
<CAPTION>
                                                                    VALUE
    SHARES                                                          (000)
- ------------------------------------------------------------
<C>              <S>                                               <C>
 
  COLOMBIA (0.7%)
     17,130,000  Banco de Colombia...............................  $  6,207
                                                                   --------
  GREECE (2.8%)
        413,369  Aegek...........................................     3,558
         76,550  Alpha Credit Bank of Athens.....................     4,425
        278,475  Delta Dairy.....................................     5,229
        165,870  Ergo Bank.......................................     6,611
        142,000  Hellenic Bottling Co............................     4,644
                                                                   --------
                                                                     24,467
                                                                   --------
  HONG KONG (9.9%)
      1,597,000  Cheung Kong Holdings Ltd........................     9,728
      2,628,000  Citic Pacific Ltd...............................     8,989
     14,327,000  C.P. Pokphand Co., Ltd..........................     5,744
       4,500,00  Florens Group Ltd...............................     2,939
         65,800  Great Wall Electric Ltd. ADR....................       242
     11,431,000  Guangdong Investments Ltd.......................     6,874
      2,686,200  Hong Kong Telecommunications Ltd................     4,794
      5,397,000  Hopewell Holdings Ltd...........................     3,106
      2,049,000  Hutchison Whampoa Ltd...........................    12,481
      3,478,000  New World Development Co., Ltd..................    15,158
       +162,400  Shandong Huaneng Power Co., Ltd., ADR...........     1,096
        617,000  Sun Hung Kai Properties Ltd.....................     5,047
        618,000  Swire Pacific Ltd., Class A.....................     4,795
      2,819,000  Varitronix International Ltd....................     5,232
      1,554,000  Wai Kee Holdings Ltd............................       195
      2,646,000  Zhenhai Refining & Chemical Co., Ltd., Class
                   H.............................................       496
                                                                   --------
                                                                     86,916
                                                                   --------
  INDIA (8.7%)
        230,000  American Dry Fruits.............................       235
            550  Andhra Valley Power Supply, Class B.............         2
        100,000  AP Rayon, Class B...............................       215
         10,000  Apollo Tyres Ltd................................        39
         77,650  Aruna Sugars & Enterprises, Class B.............        59
          9,815  Associated Cement Companies Ltd.................       800
         86,400  BPL Ltd.........................................       182
       +891,500  Balaji Foods & Feeds............................       298
          8,500  Ballapur Industries Ltd., Class B...............        45
          9,065  Baroda Rayon Corp...............................        80
         92,284  Bharat Forge Co., Ltd., Class A.................       358
      3,300,000  Bharat Heavy Electricals........................     8,258
        374,600  Bharat Pipes & Fittings Ltd., Class B...........       128
       +125,000  Bharat Pipes & Fittings Ltd. (New)..............        34
        191,642  Carrier Aircon Ltd., Class B....................       937
         90,000  Cosmo Films Ltd.................................       266
        305,000  Crompton Greaves................................     1,735
         25,900  DCL Polyesters Ltd..............................        15
         77,000  DCM Shriram Industries Ltd......................       149
         38,800  Delta Industries Ltd............................        80
        185,000  Essab India Ltd.................................       300
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Emerging Markets Portfolio
 
                                       20
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE EMERGING MARKETS PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                    VALUE
    SHARES                                                          (000)
- ------------------------------------------------------------
<C>              <S>                                               <C>
  INDIA (CONT.)
         50,000  Essel Packaging.................................  $    264
         12,000  Federal Bank Ltd................................        60
          2,370  Flex Industries Ltd., Class B...................        11
        +16,566  Flex Industries Ltd. (New)......................        67
         10,000  Fuller..........................................        48
       +557,338  Garware Plastics & Polyester, Class A...........     2,995
       +712,500  Godrej Soaps Ltd................................     1,378
      1,013,500  Great Eastern Shipping Co.......................     1,391
        203,100  Gujarat Ambuja Cements, Ltd.....................     1,568
        101,950  Hero Honda, Class B.............................       664
        104,277  Housing Development Finance Corp................     8,021
      *@+78,000  India Magnum Fund, (The) Class A (acquired
                   11/25/92-3/01/94, Cost $3,782)................     3,510
       @+55,194  India Magnum Fund, (The) Class B................     2,484
        644,625  India Organic Chemical Ltd......................       633
       +396,200  Indian Petrochemicals Corp. Ltd.................     1,392
        +40,000  Indian Seamless Steel & Alloys..................         9
       +571,197  Indo Rama Synthetic, Class B....................       570
        100,000  Infosys Technology Ltd..........................     1,160
        155,100  ITC Agrotech, Class B...........................       280
       +113,500  ITC Ltd.........................................       808
            225  ITW Signode Ltd. (New)..........................         1
        608,700  Jai Parabolic Springs Ltd.......................       476
          5,292  JCT Ltd. GDR....................................        35
       +353,231  JK Synthetics Ltd...............................       246
         78,500  Kiloskar Oil Engine, Class B....................       279
            550  Lakme Ltd., Class B.............................         4
        150,000  Lakshmi Precision...............................       252
       +145,000  Laser Lamp......................................        73
        748,800  Mahanagar Telephone Nigam.......................     3,130
         96,484  Mahavir Spinning Mills Ltd......................       307
       +425,700  Maikaal Fibres..................................       127
        159,700  Mardia Chemicals Ltd............................       238
         10,000  Modi Xerox Ltd..................................        50
    @+8,275,200  Morgan Stanley Growth Fund......................     1,412
       @+19,389  Morgan Stanley India Investment Fund, Inc.......       177
         73,631  MRF Ltd., Class B...............................     3,767
            350  Mukand Iron & Steel Works, Class A..............         2
              6  Nahar Spinning Mills Ltd., Class B..............        --
         25,000  OM Sindoori Hotels Ltd..........................        36
        250,000  Patheja Forgings & Auto Parts, Class B..........       540
       +318,935  PCS Data Products Ltd., Class B.................       127
        240,700  Philips India Ltd...............................     1,054
       +135,500  Polar Latex.....................................        42
       +232,700  Priyadarshini Cement Ltd., Class B..............       142
          8,200  Pudumjee........................................        34
        350,000  PVD Plastic Mouldings Inds. Ltd., Class B.......       181
            850  Ranbaxy Laboratories Ltd., Class B..............        16
        152,250  Raymond Ltd.....................................     1,161
           +200  Raymond Synthetics Ltd., Class B................        --
         +3,770  Reliance Industries Ltd. GDS....................        54
<CAPTION>
                                                                    VALUE
    SHARES                                                          (000)
- ------------------------------------------------------------
<C>              <S>                                               <C>
        #73,581  Reliance Industries Ltd. GDS (New)..............  $  1,030
        +25,350  Rossel Tea Ltd..................................       144
       +100,000  Saurashtra Cement & Chemicals, Class B..........       176
         29,500  SCICI Ltd.......................................        31
        +50,000  Secals Ltd......................................        84
       +104,700  Sharp Industries Ltd............................        41
        397,500  Shipping Corp. of India.........................       350
         25,000  Shree Vindhya Paper Mills.......................        57
        125,636  Shree Vindhya Paper Mills (New).................       288
            125  S.K.F. Bearings Ltd.............................         9
        +45,000  Sri Venkatesa Mills Ltd.........................       141
      1,648,550  State Bank of India.............................     9,296
           +400  Sundaram Finance, Class B.......................         2
        725,950  Super Forgings & Steels.........................       537
        272,280  Tata Engineering & Locomotive, Class A..........     2,937
         28,350  Tata Hydro Electric Power.......................        73
         +2,180  Tata Power Co. Ltd..............................         7
       +320,000  Titagarh Steels Ltd.............................       312
            600  T.P.I. India Ltd................................         1
            838  United Phosphorus Ltd. GDR......................        17
        165,500  Uniworth International Ltd., Class B............        89
     +1,566,000  Uttam Steels Ltd., Class A......................       802
            404  Videocon International Ltd., Class A............         1
       +149,100  Videsh Sanchar Nigam Ltd........................     3,519
        710,040  VXL Ltd.........................................       655
         11,000  Vysya Bank......................................       138
         +5,000  Wartsila Diesel Ltd.............................        28
                                                                   --------
                                                                     76,256
                                                                   --------
 
  INDONESIA (6.3%)
    **2,553,550  Bank Bali (Foreign).............................     5,026
    **1,703,500  Barito Pacific Timber (Foreign).................     1,248
   **+2,244,000  Bimantara Citra (Foreign).......................     1,865
    **3,359,598  Charoen Pokphand (Foreign)......................     6,832
      **168,000  Duta Pertiwi (Foreign)..........................       171
      **425,500  Hanajaya Mandala Sampoerna (Foreign)............     4,429
    **1,147,000  Indocement Tunggal (Foreign)....................     3,850
    **1,274,500  Indosat (Foreign)...............................     4,626
      **808,100  Jembo Cable Co. (Foreign).......................       521
    **1,358,200  Kalbe Farma (Foreign)...........................     4,604
      **481,000  Keramika Indonesia Assosiasi (Foreign)..........       231
    **2,096,500  Polysindo Eka Perkasa (Foreign).................     1,192
    **1,058,500  Semen Gresik (Foreign)..........................     2,963
    **4,336,200  Sona Topas Tourism (Foreign)....................     1,233
    **1,220,000  Sorini Corp. (Foreign)..........................     5,923
      **150,000  Suba Indah (Foreign)............................       100
   **+1,607,000  Telekomunikasi Indonesia (Foreign)..............     2,108
    **1,467,600  Tempo Scan Pacific (Foreign)....................     3,979
    **2,145,500  United Tractors (Foreign).......................     4,035
                                                                   --------
                                                                     54,936
                                                                   --------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                      Emerging Markets Portfolio
 
                                       21
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE EMERGING MARKETS PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                    VALUE
    SHARES                                                          (000)
- ------------------------------------------------------------
<C>              <S>                                               <C>
  ISRAEL (3.9%)
         72,200  ELBIT...........................................  $  3,851
          2,860  First International Bank of Israel, Class 1.....       335
         25,122  First International Bank of Israel, Class 5.....     3,032
        524,467  Israel Land Development.........................     1,517
         80,819  Koor Industries.................................     8,023
        543,520  Osem Investment.................................     3,250
       +137,336  PEC Israel Economic Corp........................     3,313
         54,397  Scitex Ltd......................................       741
        164,365  Super Sol Ltd., Class B.........................     3,455
        145,000  Teva Pharmaceutical Industries Ltd. ADR.........     6,724
                                                                   --------
                                                                     34,241
                                                                   --------
  KOREA (2.2%)
        **7,890  Pohang Iron & Steel (Foreign)...................       557
         71,480  Samsung Electronics (Foreign)...................    12,992
           +814  Samsung Electronics (Foreign)(New)..............       148
         +5,099  Samsung Electronics (New).......................       920
       **78,000  Shinhan Bank (Foreign)..........................     1,712
       **30,436  Shinhan Bank RFD (Foreign)......................       668
         63,000  Yukong Ltd. (Foreign)...........................     2,176
                                                                   --------
                                                                     19,173
                                                                   --------
  MALAYSIA (0.1%)
        735,000  Bandar Raya Developments Bhd....................     1,048
                                                                   --------
  MEXICO (8.7%)
        155,060  Alfa S.A. de C.V., Class A......................     1,993
        513,912  Apasco S.A., Class A............................     2,111
      4,877,920  Banacci, Class B................................     8,190
        763,554  Banacci, Class L................................     1,137
       +864,977  Cemex S.A. de C.V. CPO ADR......................     5,703
     #2,582,660  Cemex S.A., Class A.............................     8,525
     +1,752,000  Cifra S.A. de C.V., Class C.....................     1,776
         91,810  Coca-Cola Femsa S.A. ADR........................     1,699
        326,469  Empresas ICA S.A. ADR...........................     3,346
      4,533,550  FEMSA, Class B..................................    10,216
      #+152,640  Grupo Carso S.A. ADR............................     1,628
     #1,476,655  Grupo Financiero Bancomer ADR...................     8,583
     +7,541,700  Grupo Financiero Bancomer, Class B..............     2,107
       +257,551  Grupo Financiero Bancomer, Class L..............        67
        181,955  Grupo Televisa S.A. ADR.........................     4,094
      #+107,663  Hylsamex S.A. ADR...............................     2,315
        177,488  Panamerican Beverages, Inc., Class A............     5,680
        225,390  Telefonos de Mexico S.A. ADR, Class L...........     7,184
                                                                   --------
                                                                     76,354
                                                                   --------
  MOROCCO (1.7%)
         20,000  BMCE............................................       921
         55,123  Groupe Ona......................................     2,109
       +188,100  SNI Maroc, series `V'...........................     9,218
         58,221  Wafabank........................................     2,509
                                                                   --------
                                                                     14,757
                                                                   --------
<CAPTION>
                                                                    VALUE
    SHARES                                                          (000)
- ------------------------------------------------------------
<C>              <S>                                               <C>
  PAKISTAN (2.6%)
         33,480  Adamjee Insurance Co., Ltd......................  $    101
       +142,649  Cherat Cement Ltd...............................       184
         +1,814  Crescent Investment Bank........................         1
         +6,459  Crescent Textile Mills Ltd......................         4
     +1,049,500  Dewan Salman Fibre..............................     2,531
      2,288,000  D.G. Khan Cement Ltd............................     2,006
      3,017,900  Fauji Fertilizer................................     4,520
      1,880,600  Karachi Electric Supply Corp....................     1,457
        +94,273  Muslim Commercial Bank..........................       101
     +1,256,519  Nishat Mills Ltd................................     1,074
        358,020  Pakistan State Oil Co...........................     2,773
        +42,200  Pakistan Telecommunications.....................     3,793
        +27,900  Pakistan Telecommunications GDS.................     2,427
     +1,800,960  Sui Northern Gas................................     1,566
       +298,000  Zahur Textile Mills.............................        24
                                                                   --------
                                                                     22,562
                                                                   --------
  PERU (0.0%)
             35  Cementos Lima S.A...............................        --
                                                                   --------
  PHILIPPINES (5.5%)
      4,235,962  Ayala Land, Inc., Class B.......................     5,168
     +8,112,000  C&P Homes, Inc..................................     5,953
     +5,977,000  DMI Holdings, Inc...............................     2,142
     16,698,330  JG Summit Holding, Class B......................     4,584
        818,588  Manila Electric Co., Class B....................     6,679
     12,893,816  Petron Corp.....................................     6,636
        104,055  Philippine Long Distance Telephone Co., Class
                   B.............................................     5,653
      2,031,420  San Miguel Corp., Class B.......................     6,931
    +15,618,168  SM Prime Holdings, Inc., Class B................     4,466
                                                                   --------
                                                                     48,212
                                                                   --------
  POLAND (0.8%)
         20,000  Bre Bank........................................       304
         45,000  Debica..........................................       679
     ***+33,400  Eastbridge......................................     2,245
        137,620  Elektrim........................................       466
     +2,085,038  International UNP Holdings......................       703
       +373,740  Mostostal Exports, S.A..........................       735
         11,125  Wedel S.A.......................................       368
         15,735  Zywiec..........................................     1,085
                                                                   --------
                                                                      6,585
                                                                   --------
  PORTUGAL (0.2%)
        120,000  Filmes Lusomundo................................     1,283
        @+9,945  Portuguese Investment Fund Ltd. (The)...........       621
                                                                   --------
                                                                      1,904
                                                                   --------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Emerging Markets Portfolio
 
                                       22
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE EMERGING MARKETS PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                    VALUE
    SHARES                                                          (000)
- ------------------------------------------------------------
<C>              <S>                                               <C>
  RUSSIA (4.0%)
    ***+462,150  Alliance Cellulose Ltd..........................  $  9,295
     ***+54,035  Alliance Cellulose Ltd., Class B................     1,500
       +130,000  Edinaya Enegertics..............................         4
       +503,500  Irkutskenergo...................................     2,492
       +252,000  LUKoil Holding..................................     1,153
     +7,850,000  Moscow Energy...................................     2,080
       +605,000  Rostelecom......................................     2,829
    ***+317,851  Russian Telecom Development Corp................     3,179
    ***+400,000  SFMT, Inc.......................................     4,000
        ***+990  Storyfirst Communications, Inc., Class C........       660
      ***+2,640  Storyfirst Communications, Inc., Class D........     1,980
      ***+3,250  Storyfirst Communications, Inc., Class E........     3,250
    +88,909,000  Unified Energy System...........................     2,703
                                                                   --------
                                                                     35,125
                                                                   --------
  SOUTH AFRICA (2.3%)
         44,830  Anglo American Industrial Corp., Ltd............     2,038
        700,000  Bidvest.........................................     4,705
        860,000  Gencor..........................................     2,996
       @224,490  Morgan Stanley Africa Investment Fund, Inc......     2,890
        972,084  Sasol Ltd.......................................     7,960
                                                                   --------
                                                                     20,589
                                                                   --------
  TAIWAN (4.5%)
     +1,873,000  Acer, Inc.......................................     4,324
       +909,000  Advanced Semiconductor Engineering, Inc.,.......     2,199
      3,492,000  China Steel Corp................................     2,790
        100,000  Far East Textiles...............................        95
     +1,117,986  Mosel Vitelic Ltd...............................     3,319
     +2,027,999  Shinkong Synthetic Fiber........................     1,754
     +3,812,800  Taiwan Semiconductor Manufacturing Co...........    11,947
      3,905,836  United Micro Electronics Corp., Ltd.............     9,805
       +336,000  Walsin Lihwa Corp. GDR..........................     3,368
                                                                   --------
                                                                     39,601
                                                                   --------
  THAILAND (5.0%)
        298,550  Advanced Information Services Co., Ltd.
                   (Foreign).....................................     5,286
        785,400  Bangkok Bank Ltd. (Foreign).....................     9,541
      2,398,300  Finance One Co., Ltd. (Foreign).................    16,661
        144,600  Shinawatra Computer Co., Ltd. (Foreign).........     3,559
        257,400  Thai Farmers Bank Ltd...........................     1,757
        727,100  Thai Farmers Bank Ltd. (Foreign)................     7,332
                                                                   --------
                                                                     44,136
                                                                   --------
<CAPTION>
                                                                    VALUE
    SHARES                                                          (000)
- ------------------------------------------------------------
<C>              <S>                                               <C>
  TURKEY (5.4%)
      6,065,172  Aksa............................................  $  1,867
      2,868,000  Bagfas..........................................       883
     11,278,000  Borusan.........................................     2,269
    +13,272,000  Bossa...........................................       948
     +4,000,000  Demirbank TAS...................................       243
     30,329,180  Ege Biracilik...................................    10,458
      4,600,000  Ege Seramik.....................................     1,095
      4,226,000  Erciyas Biracilik...............................     1,978
     38,125,000  Eregli Demir....................................     3,130
      3,479,000  Guney Biracilik Ve Malt Sanayii.................       509
      2,998,800  Migros..........................................     2,290
     85,761,000  Sabah...........................................     1,690
     14,346,000  Sarkuysan.......................................     2,120
      8,687,000  Tat Konserve Sanayli............................     5,492
     40,206,000  Tofas Turk Otomobil Fabrikasi...................     3,895
        498,288  Tofas Turk Otomobil Fabrikasi GDR, Class E......       249
     28,340,000  Trakya Cam Sanayii..............................     2,885
      1,354,075  Turkas Petroculuk A.S...........................       239
    #11,439,000  Turkiye Garanti Bankasi A.S.....................       958
        220,482  Turkiye Garanti Bankasi ADR.....................     1,846
     46,537,600  Yapi Ve Kredi Bankasi A.S.......................     1,911
                                                                   --------
                                                                     46,955
                                                                   --------
  UNITED KINGDOM (0.3%)
        915,713  Lonrho plc......................................     2,502
                                                                   --------
  ZIMBABWE (0.3%)
    #+1,980,000  Trans Zambezi Industries Ltd....................     2,871
        +35,281  Trans Zambezi Industries Ltd., Class S..........        51
                                                                   --------
                                                                      2,922
                                                                   --------
TOTAL COMMON STOCKS (Cost $790,607)..............................   737,077
                                                                   --------
PREFERRED STOCKS (10.8%)
  BRAZIL (NON-VOTING STOCKS) (10.7%)
**1,754,000,000  Banco Bradesco S.A..............................    15,339
   +467,646,000  Banco do Brasil.................................     5,293
  **295,998,880  Banco Nacional S.A..............................       609
     40,268,030  Brahma..........................................    16,574
        620,000  Brasmotor S.A...................................       123
     73,517,103  Cia Energetica de Minas Gerais..................     1,626
     16,959,000  Cia Paulista de Forca E Luz.....................       454
     84,212,850  Eletrobras, Class B.............................    22,788
     32,803,800  Itaubanco.......................................     9,147
     37,930,101  Lojas Americanas S.A............................       890
        105,758  Lojas Americanas S.A. (Bonus Shares Plan).......        15
     44,869,333  Petrobras.......................................     3,831
         12,500  Sadia Concordia.................................         9
    175,858,000  Telebras........................................     8,468
     32,080,815  Telecomunicacoes de Sao Paulo...................     4,720
    526,000,000  Usiminas........................................       428
     21,118,000  Vale Do Rio Doce................................     3,477
                                                                   --------
                                                                     93,791
                                                                   --------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                      Emerging Markets Portfolio
 
                                       23
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE EMERGING MARKETS PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                    VALUE
    SHARES                                                          (000)
- ------------------------------------------------------------
<C>              <S>                                               <C>
  GREECE (0.1%)
        121,458  Aegek...........................................  $    666
                                                                   --------
  INDIA (0.0%)
          2,700  Fabworth (India) Ltd............................         2
                                                                   --------
  PORTUGAL (0.0%)
         35,340  Filmes Lusomundo................................       330
                                                                   --------
TOTAL PREFERRED STOCKS (Cost $88,639)............................    94,789
                                                                   --------
<CAPTION>
    NO. OF
    RIGHTS
- ---------------
<C>              <S>                                               <C>
RIGHTS (0.1%)
  BRAZIL (0.0%)
       **43,545  Banco Bradesco..................................       113
                                                                   --------
  INDIA (0.1%)
       **+9,610  Baroda Rayon Corp...............................        --
         +6,000  Federal Bank Ltd................................         5
           +674  Flex Industries Ltd.............................        --
     **+155,100  ITC Agrotech....................................        --
           **+2  Nahar Spinning..................................        --
       +133,300  SCICI Ltd. (Bonus)..............................       139
        +55,000  Vysya Bank......................................       618
                                                                   --------
                                                                        762
                                                                   --------
  PAKISTAN (0.0%)
       +686,400  D.G. Khan Cement................................       241
        +20,625  Dewan Salman....................................        --
                                                                   --------
                                                                        241
                                                                   --------
TOTAL RIGHTS (Cost $579).........................................     1,116
                                                                   --------
<CAPTION>
 
    NO. OF
   WARRANTS
- ---------------
<C>              <S>                                               <C>
WARRANTS (1.0%)
  INDIA (0.1%)
      **+33,571  Bharat Forge Co., Ltd. (New)....................       130
      **+27,383  Flex Industries Ltd., expiring 11/23/97.........       103
      **+44,702  Garware Plastics & Polyesters, expiring
                   4/04/98.......................................       346
                                                                   --------
                                                                        579
                                                                   --------
  INDONESIA (0.0%)
       +274,600  Bank Bali, expiring 8/29/00.....................       120
                                                                   --------
  POLAND (0.0%)
   **+1,014,000  International UNP Holdings......................        --
                                                                   --------
  RUSSIA (0.9%)
         +9,640  LUKoil Holding..................................     7,712
                                                                   --------
  THAILAND (0.0%)
          **+10  Finance One Co., Ltd., expiring 3/15/99.........        --
                                                                   --------
TOTAL WARRANTS (Cost $10,050)....................................     8,411
                                                                   --------
<CAPTION>
 
     FACE
    AMOUNT                                                          VALUE
     (000)                                                          (000)
- ------------------------------------------------------------
<C>              <S>                                               <C>
CONVERTIBLE DEBENTURES (0.6%)
  COLOMBIA (0.5%)
  U.S.$  #5,615  Banco de Colombia 5.20%, 2/01/99................  $  4,267
                                                                   --------
  INDIA (0.1%)
  INR  **33,574  DCM Shriram Industries Ltd. 15.00%, 3/02/02.....       448
          1,650  Indian Seamless Steel & Alloys 10.00%,
                   7/13/96.......................................        27
            130  Tata Iron & Steel, 2.25%, 4/01/99...............       116
                                                                   --------
                                                                        591
                                                                   --------
TOTAL CONVERTIBLE DEBENTURES (Cost $6,122).......................     4,858
                                                                   --------
NON-CONVERTIBLE DEBENTURES (0.5%)
  INDIA (0.5%)
          3,357  Bharat Forge Co., Ltd., 14.50%, 4/18/02.........        43
         34,055  DCM Shriram Industries Ltd., 16.50%, 3/02/02....       599
          4,470  Garware Plastics & Polyester, 16.00%, 4/04/98...       127
          1,467  Mahavir Spinning Mills Ltd., Series A, 15.40%,
                   3/22/00.......................................        40
         50,000  Raymond Ltd., 16.00%, 1/05/02...................     1,422
         70,000  Saurashtra Cement & Chemicals Ltd., 18.00%,
                   11/27/98......................................     2,239
                                                                   --------
TOTAL NON-CONVERTIBLE DEBENTURES (Cost $5,071)...................     4,470
                                                                   --------
LOAN AGREEMENTS (1.2%)
  POLAND (0.0%)
  U.S.$     #54  Republic of Poland Interest Arrears PDI Bonds,
                   3.75%, 10/27/14...............................        35
                                                                   --------
  RUSSIA (1.2%)
   CHF ++11,910  Bank for Foreign Economic Affairs (Floating
                   Rate).........................................     3,485
 U.S.$ ++21,003  Bank for Foreign Economic Affairs (Floating
                   Rate).........................................     7,167
                                                                   --------
                                                                     10,652
                                                                   --------
TOTAL LOAN AGREEMENTS (Cost $9,781)..............................    10,687
                                                                   --------
TOTAL FOREIGN SECURITIES (98.3%) (Cost $910,849).................   861,408
                                                                   --------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Emerging Markets Portfolio
 
                                       24
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE EMERGING MARKETS PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
    AMOUNT                                                          VALUE
     (000)                                                          (000)
- ------------------------------------------------------------
<C>              <S>                                               <C>
FOREIGN CURRENCY (1.1%)
ARP       213  Argentine Peso....................................  $    213
BRC     1,000  Brazilian Real....................................     1,029
COP   512,134  Colombian Peso....................................       517
HKD     2,753  Hong Kong Dollar..................................       356
HUF    59,707  Hungarian Forint..................................       437
INR   186,311  Indian Rupee......................................     5,298
MXP       452  Mexican Peso......................................        59
MAD     1,419  Morrocan Dirham...................................       168
PKR    12,099  Pakistani Rupee...................................       354
PSS     2,126  Peruvian New Sol..................................       920
PLZ       224  Polish Zloty......................................        91
LKR     8,042  Sri Lankan Rupee..................................       150
TWD     5,118  Taiwan Dollar.....................................       187
THB     3,262  Thai Baht.........................................       129
                                                                   --------
TOTAL FOREIGN CURRENCY (Cost $10,194)............................     9,908
                                                                   --------
TOTAL INVESTMENTS (99.4%) (Cost $921,043)........................   871,316
                                                                   --------
</TABLE>
 
<TABLE>
<CAPTION>
OTHER ASSETS (2.9%)
<S>                                                 <C>            <C>
  Receivable for Investments Sold.................  $      21,080
  Dividends Receivable............................          1,908
  Receivable for Portfolio Shares Sold............          1,139
  Interest Receivable.............................            403
  Foreign Withholding Tax Reclaim Receivable......            112
  Other...........................................            367    25,009
                                                    -------------
LIABILITIES (-2.3%)
  Payable for Investments Purchased...............        (12,102)
  Investment Advisory Fees Payable................         (3,005)
  Payable for Portfolio Shares Redeemed...........         (2,038)
  Bank Overdraft..................................         (1,487)
  Custodian Fees Payable..........................           (400)
  Deferred India Taxes............................           (308)
  Administrative Fees Payable.....................           (119)
  Payable for India Stamp Duty Tax................           (101)
  Sub-Administrative Fees Payable.................            (34)
  Net Unrealized Loss on Forward Foreign Currency
    Exchange Contracts............................            (10)
  Payable for India Taxes.........................             (1)
  Other Liabilities...............................           (129)  (19,734)
                                                    -------------  --------
NET ASSETS (100%)................................................  $876,591
                                                                   --------
                                                                   --------
NET ASSET VALUE, OFFERING AND REDEMPTION PRICE PER
  SHARE
  Applicable to 66,716,021 outstanding $.001 par value shares
  (authorized 500,000,000 shares)................................    $13.14
                                                                   --------
                                                                   --------
</TABLE>
 
FORWARD FOREIGN CURRENCY EXCHANGE CONTRACT INFORMATION:
   Under the terms of forward foreign currency exchange contracts open at
   December 31, 1995, the Portfolio is obligated to deliver foreign currency in
   exchange for U.S. dollars as indicated below:
 
<TABLE>
<CAPTION>
                                        IN                       NET
 CURRENCY                            EXCHANGE                UNREALIZED
TO DELIVER    VALUE    SETTLEMENT       FOR        VALUE        LOSS
  (000)       (000)       DATE         (000)       (000)        (000)
- ----------  ---------  -----------  -----------  ---------  -------------
<S>         <C>        <C>          <C>          <C>        <C>
HKD  2,722  $     352     1/02/96     U.S.$352   $     352    $      --
PSS  2,000        866     1/02/96     U.S.$856         856          (10)
            ---------                            ---------          ---
            $   1,218                            $   1,208    $     (10)
            ---------                            ---------          ---
            ---------                            ---------          ---
</TABLE>
<TABLE>
<S>        <C>        <C>
- ------------------------------------------------
+          --         Non-income producing security
++         --         Non-income producing security -- in
                      default
*          --         Restricted as to public resale. Total
                      value of restricted securities at
                      December 31, 1995, was $3,510 or 0.4% of
                      net assets. (Total cost $3,782).
**         --         Securities (totaling U.S.$74,961 or 8.6%
                      of net assets at December 31, 1995)
                      valued at fair value -- See Note A-1
***        --         Security is valued at cost -- See Note
                      A-1
#          --         144A Securities -- Certain conditions for
                      public sale may exist
@          --         The fund is advised by an affiliate
ADR        --         American Depositary Receipt
ADS        --         American Depositary Shares
CPO        --         Certificate of Participation
GDR        --         Global Depositary Receipt
GDS        --         Global Depositary Shares
RFD        --         Ranked For Dividend
CHF        --         Swiss Franc
 
<CAPTION>
- ---------------------------------------------------------------
</TABLE>
 
            SUMMARY OF FOREIGN SECURITIES BY INDUSTRY CLASSIFICATION
                                  (UNAUDITED)
 
<TABLE>
<CAPTION>
                                          VALUE     PERCENT OF
INDUSTRY                                  (000)     NET ASSETS
<S>                                     <C>        <C>
- ----------------------------------------------------------------
Capital Equipment.....................  $  86,196         9.8%
Consumer Goods........................    125,580        14.3
Energy................................    116,660        13.3
Finance...............................    207,434        23.7
Loan Agreements.......................     10,687         1.2
Materials.............................    138,556        15.9
Multi-Industry........................     76,846         8.8
Services..............................     99,449        11.3
                                        ---------       -----
                                        $ 861,408        98.3%
                                        ---------       -----
                                        ---------       -----
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                      Emerging Markets Portfolio

                                       25
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE EUROPEAN EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                 VALUE
  SHARES                                                         (000)
      ------------------------------------------------------------
<C>         <S>                                                 <C>
COMMON STOCKS (94.8%)
  BELGIUM (2.9%)
    +9,000  Arbed S.A.........................................  $  1,019
    11,000  Delhaize Freres et Cie, 'Le Lion' S.A.............       456
    12,000  G.I.B. Holdings Ltd...............................       527
        55  G.I.B. Holdings Ltd. VVPR (New)...................         2
                                                                --------
                                                                   2,004
                                                                --------
  DENMARK (1.5%)
    21,300  Unidanmark A/S, Class A (Registered)..............     1,054
                                                                --------
  FINLAND (3.1%)
    55,500  Amer-Yhtymae Oy, Class A..........................       866
    25,000  Huhtamaki Oy, Series 1............................       604
   +13,533  Merita, Ltd., Class A.............................        34
   +10,500  Nokia AB Oy, Class A..............................       413
    20,000  Pohjola Insurance Co., Ltd., Class B..............       257
                                                                --------
                                                                   2,174
                                                                --------
  FRANCE (13.9%)
    23,500  Banque Nationale de Paris.........................     1,060
     1,700  Bongrain S.A......................................       958
     7,000  Cie de Saint Gobain...............................       775
   +10,000  Credit Lyonnaise CDI..............................       480
    15,000  Elf Aquitaine.....................................     1,105
     8,000  Eridania Beghin-Say S.A...........................     1,372
   +21,405  Legris Industries S.A.............................       697
     4,100  Labinal S.A.......................................       455
     7,000  Peugeot S.A.......................................       923
    45,452  Thomson CSF.......................................     1,013
    12,000  Total S.A., Class B...............................       810
                                                                --------
                                                                   9,648
                                                                --------
  GERMANY (11.9%)
     6,000  BASF AG...........................................     1,352
     5,000  Bayer AG..........................................     1,328
   +16,000  Bremer Vulkan Verbund AG..........................       446
     3,500  Commerzbank AG....................................       831
     2,200  Karstadt AG.......................................       902
     2,500  Mannesmann AG.....................................       796
    +3,700  Varta AG..........................................       710
    22,000  Veba AG...........................................       942
     3,000  Volkswagen AG.....................................     1,006
                                                                --------
                                                                   8,313
                                                                --------
  ITALY (6.7%)
  +518,000  Editoriale L'Expresso S.p.A.......................       897
  +520,000  Impregilo S.p.A...................................       439
   540,000  Olivetti S.p.A....................................       433
   200,700  Sogefi S.p.A......................................       425
   500,000  Stet Di Risp (NCS)................................     1,020
   205,500  Telecom Italia S.p.A..............................       320
   410,000  Telecom Italia S.p.A. Di Risp (NCS)...............       501
  +242,200  Unicem Di Risp (NCS)..............................       614
                                                                --------
                                                                   4,649
                                                                --------
  NETHERLANDS (11.7%)
    29,674  ABN Amro Holdings N.V.............................     1,352
 
<CAPTION>
                                                                 VALUE
  SHARES                                                         (000)
      ------------------------------------------------------------
<C>         <S>                                                 <C>
     9,500  Akzo Nobel N.V....................................  $  1,099
       950  DSM N.V...........................................        78
     7,599  Hollandsche Beton Groep N.V.......................     1,160
    13,084  Internationale Nederlanden Groep N.V..............       874
    13,000  Koninklijke Bijenkorf Beheer N.V..................       859
    30,468  Koninklijke PTT Nederland N.V.....................     1,107
    25,000  Koninklijke Van Ommeren N.V.......................       779
    23,500  Philips Electronics N.V...........................       849
                                                                --------
                                                                   8,157
                                                                --------
  NORWAY (1.9%)
   200,000  Den Norske Bank A/S, Class A Free.................       524
     5,113  Hafslund Nycomed, Class B.........................       130
    53,000  Saga Petroleum A/S, Class B.......................       662
                                                                --------
                                                                   1,316
                                                                --------
  PORTUGAL (0.2%)
   +@1,905  Portuguese Investment Fund........................       119
                                                                --------
  SPAIN (8.4%)
  +100,000  Asturiana del Zinc S.A............................       793
    17,000  Banco de Santander S.A............................       854
    11,518  Bodegas y Bebidas S.A.............................       294
  +107,870  Grupo Duro Felguera S.A...........................       381
   110,000  Iberdrola S.A.....................................     1,007
   106,000  Sevillana de Electricidad S.A.....................       823
   125,000  Telefonica Nacional de Espana S.A.................     1,731
                                                                --------
                                                                   5,883
                                                                --------
  SWEDEN (3.0%)
     1,700  Electrolux AB, Series B...........................        70
   +50,000  Nordbanken AS.....................................       866
    59,000  S.K.F. AB, Class B................................     1,128
                                                                --------
                                                                   2,064
                                                                --------
  SWITZERLAND (15.1%)
      +800  Ascom Holdings AG (Bearer)........................       815
       460  Bobst AG (Bearer).................................       718
       700  Ciba Geigy AG (Bearer)............................       613
       800  Ciba-Geigy AG (Registered)........................       704
     2,200  Forbo Holding AG (Registered).....................       940
     1,030  Hero Lenzburg AG (Bearer).........................       509
     1,400  Magazine Globus (Participating Certificates)......       801
     1,100  Nestle S.A. (Registered)..........................     1,217
   +16,100  Oerlikon-Buehrle Holding AG (Registered)..........     1,312
     1,000  Schweizerische Industrie-Gesellschaft Holdings
              (Registered)....................................     1,014
     1,800  Sulzer AG (Participating Certificates)............       960
    +1,200  SwissAir (Registered).............................       874
                                                                --------
                                                                  10,477
                                                                --------
  UNITED KINGDOM (14.5%)
  +145,500  Asprey plc........................................       565
   140,000  Associated British Foods plc......................       802
    20,000  Bass plc..........................................       223
   200,000  BET plc...........................................       394
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
European Equity Portfolio
 
                                       28
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE EUROPEAN EQUITY PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                 VALUE
  SHARES                                                         (000)
      ------------------------------------------------------------
<C>         <S>                                                 <C>
  UNITED KINGDOM (CONT.)
    70,000  BSM Group plc.....................................  $    168
    32,800  Calor Group plc...................................       130
   350,000  Christian Salvesen plc............................     1,437
    38,900  Courtaulds Textiles plc...........................       215
   188,491  John Mowlem & Co. plc.............................       174
   114,000  Kwik Save Group plc...............................       892
    24,895  McAlpine (Alfred) plc.............................        57
   101,075  Reckitt & Colman plc..............................     1,119
   298,566  Rolls-Royce plc...................................       876
   202,527  Royal Insurance Holdings plc......................     1,201
    46,000  Sketchley plc.....................................        90
    50,000  Tate & Lyle plc...................................       366
    30,000  Unilever plc......................................       616
   300,000  WPP Group plc.....................................       764
                                                                --------
                                                                  10,089
                                                                --------
TOTAL COMMON STOCKS (Cost $63,242)............................    65,947
                                                                --------
PREFERRED STOCKS (3.0%)
  GERMANY (3.0%)
     2,500  RWE AG............................................       698
     3,000  Spar Handels AG...................................       644
     3,200  Volkswagen AG.....................................       776
                                                                --------
TOTAL PREFERRED STOCKS (Cost $2,010)..........................     2,118
                                                                --------
TOTAL FOREIGN SECURITIES (97.8%) (Cost $65,252)...............    68,065
                                                                --------
<CAPTION>
 
   FACE
  AMOUNT
  (000)
- ----------
<C>         <S>                                                 <C>
SHORT-TERM INVESTMENT (0.5%)
  REPURCHASE AGREEMENT (0.5%)
$      336  The Chase Manhattan Bank N.A., 5.35%, dated
              12/29/95, due 1/02/96, to be repurchased at
              $336, collateralized by $250 United States
              Treasury Bonds 8.875%, due 8/15/17, valued at
              $342 (Cost $336)................................       336
                                                                --------
FOREIGN CURRENCY (3.2%)
 GBP   227  British Pound.....................................       352
 DEM 1,788  Deutsche Mark.....................................     1,248
 FIM   949  Finnish Markka....................................       218
 ITL   751  Italian Lira......................................        --
 NLG   121  Netherlands Guilder...............................        76
 ESP     2  Spanish Peseta....................................        --
 SEK 2,077  Swedish Krona.....................................       313
                                                                --------
TOTAL FOREIGN CURRENCY (Cost $2,199)..........................     2,207
                                                                --------
TOTAL INVESTMENTS (101.5%) (Cost $67,787).....................    70,608
                                                                --------
</TABLE>
<TABLE>
<CAPTION>
                                                        AMOUNT
                                                        (000)
  <S>                                                 <C>         <C>
                                                          -----
  OTHER ASSETS (0.4%)
    Receivable for Investments Sold.................  $     140
    Dividends Receivable............................         79
 
<CAPTION>
                                                        AMOUNT
                                                        (000)
        ------------------------------------------------------------
  <S>                                                 <C>         <C>
    Foreign Withholding Tax Reclaim Receivable......  $      62
    Net Unrealized Gain on Forward Foreign Currency
     Exchange Contracts.............................         20
    Receivable for Portfolio Shares Sold............         10
    Other...........................................          2   $   313
                                                          -----
  LIABILITIES (-1.9%)
    Payable for Investments Purchased...............       (710)
    Payable for Portfolio Shares Redeemed...........       (457)
    Investment Advisory Fees Payable................       (112)
    Custodian Fees Payable..........................        (12)
    Administrative Fees Payable.....................        (11)
    Other Liabilities...............................        (36)    (1,338)
                                                          -----   --------
  NET ASSETS (100%).............................................   $69,583
                                                                  --------
                                                                  --------
  NET ASSET VALUE, OFFERING AND
    REDEMPTION PRICE PER SHARE
    Applicable to 4,999,857 outstanding $.001 par value shares
    (authorized 500,000,000 shares).............................    $13.92
                                                                  --------
                                                                  --------
  ------------------------------------------------------------------------
  FORWARD FOREIGN CURRENCY EXCHANGE CONTRACT INFORMATION:
    Under the terms of forward foreign currency exchange contracts open at
    December 31, 1995, the Portfolio is obligated to deliver foreign
    currency in exchange for U.S. dollars or foreign currency as indicated
    below:
</TABLE>
 
<TABLE>
<CAPTION>
                                        IN                      NET
 CURRENCY                            EXCHANGE               UNREALIZED
TO DELIVER    VALUE    SETTLEMENT      FOR        VALUE     GAIN (LOSS)
  (000)       (000)       DATE        (000)       (000)        (000)
- ----------  ---------  -----------  ----------  ---------  -------------
<S>         <C>        <C>          <C>         <C>        <C>
NLG  121    $      75     1/02/96   U.S.$   75  $      75    $      --
ESP 9,556          79     1/03/96   DEM    113         79           --
CHF 2,750       2,422     6/10/96   U.S.$2,420      2,420           (2)
DEM 3,000       2,107     6/10/96   U.S.$2,152      2,152           45
FRF 7,100       1,451     6/10/96   U.S.$1,422      1,422          (29)
DEM 400           282     8/09/96   U.S.$  288        288            6
            ---------                           ---------          ---
            $   6,416                           $   6,436    $      20
            ---------                           ---------          ---
            ---------                           ---------          ---
</TABLE>
 
- ------------------------------------------------------------
 
<TABLE>
<S>        <C>        <C>
+             --      Non-income producing security
@             --      The fund is advised by an affiliate.
CDI           --      Certificate of Investment
NCS           --      Non Convertible Shares
CHF           --      Swiss Franc
FRF           --      French Franc
</TABLE>
 
- ------------------------------------------------------------
 
            SUMMARY OF FOREIGN SECURITIES BY INDUSTRY CLASSIFICATION
<TABLE>
<CAPTION>
                           (UNAUDITED)
<S>                                   <C>        <C>
                                        VALUE        PERCENT
INDUSTRY                                (000)     OF NET ASSETS
 
<CAPTION>
- -----------------------------------------------------------------
<S>                                   <C>        <C>
Capital Equipment...................  $  11,080          15.9%
Consumer Goods......................     14,873          21.4
Energy..............................      5,170           7.4
Finance.............................      9,945          14.3
Materials...........................     11,835          17.0
Multi-Industry......................      2,559           3.7
Services............................     12,603          18.1
                                      ---------           ---
                                      $  68,065          97.8%
                                      ---------           ---
                                      ---------           ---
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                       European Equity Portfolio
 
                                       29
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE GLOBAL EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>          <S>                                                 <C>
COMMON STOCKS (81.7%)
  AUSTRALIA (1.2%)
     50,000  Brambles Industries Ltd...........................  $    557
    120,000  Westpac Banking Corp..............................       532
                                                                 --------
                                                                    1,089
                                                                 --------
  CANADA (0.4%)
     22,900  Hudson's Bay Co...................................       329
                                                                 --------
  FRANCE (5.0%)
     10,300  Banque Nationale de Paris.........................       465
      1,870  Bongrain S.A......................................     1,054
    +12,000  Credit Lyonnaise CDI..............................       576
     19,266  Elf Aquitaine.....................................     1,419
      4,900  Labinal S.A.......................................       543
     11,965  Valeo S.A.........................................       554
                                                                 --------
                                                                    4,611
                                                                 --------
  GERMANY (6.6%)
      5,200  BASF AG...........................................     1,171
      3,822  Bayer AG..........................................     1,015
      3,600  Karstadt AG.......................................     1,476
      3,000  Mannesmann AG.....................................       955
      2,764  Sinn AG...........................................       520
     +2,225  Varta AG..........................................       427
     10,100  Veba AG...........................................       433
        260  Volkswagen AG.....................................        87
                                                                 --------
                                                                    6,084
                                                                 --------
  IRELAND (2.9%)
    757,742  Anglo Irish Bank Corp. plc........................       728
     73,900  Arnotts plc.......................................       385
    470,000  Avonmore Foods plc, Class A.......................       956
    229,312  Green Property plc................................       617
                                                                 --------
                                                                    2,686
                                                                 --------
  ITALY (2.0%)
    500,000  Stet Di Risp (NCS)................................     1,020
    700,000  Telecom Italia S.p.A. Di Risp (NCS)...............       856
                                                                 --------
                                                                    1,876
                                                                 --------
  JAPAN (9.7%)
        160  East Japan Railway Co.............................       778
     65,000  Fuji Photo Film Ltd...............................     1,876
     24,000  Hitachi Ltd.......................................       242
    110,000  Kao Corp..........................................     1,364
    155,000  Nichido Fire & Marine Insurance Co................     1,246
     18,000  Sony Corp.........................................     1,079
    100,000  Sumitomo Rubber Industries........................       835
      5,000  TDK Corp..........................................       255
     40,000  Toyo Seikan Kaisha Ltd............................     1,197
                                                                 --------
                                                                    8,872
                                                                 --------
  NETHERLANDS (6.5%)
     39,606  ABN Amro Holdings N.V.............................     1,804
      2,101  Hollandsche Beton Groep N.V.......................       321
     23,159  Internationale Nederlanden Groep N.V..............     1,547
     40,000  Koninklijke Van Ommeren N.V.......................     1,246
 
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>          <S>                                                 <C>
     15,160  Nedlloyd Groep N.V................................  $    344
     20,000  Philips Electronics N.V...........................       723
                                                                 --------
                                                                    5,985
                                                                 --------
  SINGAPORE (0.7%)
    220,000  Jardine Strategic Holdings, Inc...................       673
                                                                 --------
  SPAIN (2.6%)
     89,500  Iberdrola S.A.....................................       819
    112,300  Telefonica de Espana S.A..........................     1,555
                                                                 --------
                                                                    2,374
                                                                 --------
  SWITZERLAND (6.2%)
       +500  Ascom Holding AG (Bearer).........................       509
        800  Bobst AG (Bearer).................................     1,248
      1,800  Ciba-Geigy AG (Registered)........................     1,584
      1,400  Forbo Holding AG (Registered).....................       599
      1,400  Magazine Globus (Participating Certificates)......       801
        900  Schweizerische Industrie-Gesellschaft Holdings
               (Registered)....................................       913
                                                                 --------
                                                                    5,654
                                                                 --------
  UNITED KINGDOM (5.8%)
     28,500  Calor Group plc...................................       113
    298,700  Christian Salvesen plc............................     1,227
     40,300  Forte plc.........................................       207
    100,000  John Mowlem & Co. plc.............................        92
    150,000  Kwik Save Group plc...............................     1,174
    180,000  Matthews (Bernard) plc............................       265
 +**653,333  Pentos plc........................................        --
    102,115  Pilkington plc....................................       320
     73,902  Rolls-Royce plc...................................       218
     46,400  Unilever plc......................................       953
    279,000  WPP Group plc.....................................       710
                                                                 --------
                                                                    5,279
                                                                 --------
  UNITED STATES (32.1%)
    +89,000  Addington Resources, Inc..........................     1,302
     18,000  Aluminum Company of America.......................       952
    +15,400  AMR Corp..........................................     1,143
     32,100  Bank of New York Co., Inc.........................     1,565
    +50,500  Beazer Homes USA, Inc.............................     1,042
   +128,000  Cadiz Land Co., Inc...............................       736
   +*22,000  Cadiz Land Co., Inc. (acquired 4/17/94, Cost
               $88)............................................       127
    108,000  Comsat Corp.......................................     2,012
    +40,000  Cray Research, Inc................................       990
    +80,000  Data General Corp.................................     1,100
    +99,500  Egghead, Inc......................................       640
     50,000  Enhance Financial Services Group, Inc.............     1,331
     45,000  Finova Group, Inc.................................     2,170
     16,000  Gap, Inc..........................................       671
      2,000  General Motors Corp...............................       106
   +134,200  GenRad, Inc.......................................     1,292
     16,000  Georgia Pacific Corp..............................     1,098
      2,600  Houghton Mifflin Co...............................       112
    +31,000  Kaiser Ventures, Inc..............................       403
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Global Equity Portfolio
 
                                       32
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE GLOBAL EQUITY PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>          <S>                                                 <C>
  UNITED STATES (CONT.)
     24,300  Lukens, Inc.......................................  $    699
     13,000  MBIA, Inc.........................................       975
     61,400  MCI Communications Corp...........................     1,604
     23,300  Mellon Bank Corp..................................     1,252
    +31,300  Nexthealth Inc....................................        98
     18,600  Philip Morris Cos., Inc...........................     1,683
     12,000  Prime Retail, Inc.................................       143
     25,000  Sun Co., Inc......................................       684
     13,100  Tecumseh Products Co., Class A....................       678
     27,000  UST Corp..........................................       392
    +70,000  Waban, Inc........................................     1,313
   +107,000  WorldCorp, Inc....................................     1,070
                                                                 --------
                                                                   29,383
                                                                 --------
  TOTAL COMMON STOCKS (Cost $66,115)...........................    74,895
                                                                 --------
PREFERRED STOCKS (0.8%)
  GERMANY (0.8%)
      3,000  Volkswagen AG (Cost $647).........................       728
                                                                 --------
CONVERTIBLE PREFERRED SECURITY (0.0%)
  SINGAPORE (0.0%)
    +21,000  Jardine Strategic Holdings, Inc., IDR, 7.50%,
               5/07/97, (Cost $ 21)............................        23
                                                                 --------
</TABLE>
 
<TABLE>
<CAPTION>
  NO. OF
  RIGHTS
- -----------
<C>          <S>                                                 <C>
RIGHTS (0.1%)
  UNITED KINGDOM (0.1%)
    +25,528  Pilkington plc (Cost $61).........................        79
                                                                 --------
TOTAL FOREIGN & U.S. SECURITIES (82.6%) (Cost $66,844).........    75,725
                                                                 --------
</TABLE>
 
<TABLE>
<CAPTION>
   FACE
  AMOUNT
   (000)
- -----------
<C>          <S>                                                 <C>
SHORT-TERM INVESTMENT (2.3%)
  REPURCHASE AGREEMENT (2.3%)
 $    2,145  The Chase Manhattan Bank, N.A., 5.35%, dated
               12/29/95 due 1/02/96, to be repurchased at
               $2,147, collateralized by $1,975 United States
               Treasury Bonds, 7.50%, due 11/15/01, valued at
               $2,190 (Cost $2,145)............................     2,145
                                                                 --------
FOREIGN CURRENCY (0.6%)
   GBP    4  British Pound.....................................         6
  JPY 1,014  Japanese Yen......................................        10
   NLG  812  Netherlands Guilder...............................       506
  ESP     2  Spanish Peseta....................................        --
  SEK     1  Swedish Krona.....................................        --
                                                                 --------
TOTAL FOREIGN CURRENCY (Cost $519).............................       522
                                                                 --------
TOTAL INVESTMENTS (85.5%) (Cost $69,508).......................    78,392
                                                                 --------
</TABLE>
 
<TABLE>
<CAPTION>
                                                                  AMOUNT
                                                                  (000)
<S>                                                 <C>          <C>
- ------------------------------------------------------------
OTHER ASSETS (14.9%)
  Receivable for Portfolio Shares Sold............      $10,259
  Receivable for Investments Sold.................        3,158
  Dividends Receivable............................          135
  Foreign Withholding Tax Reclaim Receivable......           55
  Interest Receivable.............................            1
  Other...........................................            6  $13,614
                                                    -----------
LIABILITIES (-0.4%)
  Investment Advisory Fees Payable................         (141)
  Unrealized Loss on Forward Foreign Currency
    Exchange Contracts............................         (131)
  Custodian Fees Payable..........................          (12)
  Administrative Fees Payable.....................          (12)
  Payable for Investments Purchased...............           (2)
  Other Liabilities...............................          (33)    (331 )
                                                    -----------  --------
NET ASSETS (100%)..............................................  $91,675
                                                                 --------
                                                                 --------
</TABLE>
 
<TABLE>
<C>          <S>                                                 <C>
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 6,408,275 outstanding $.001 par value
  shares (authorized 500,000,000 shares).......................    $14.31
                                                                 --------
                                                                 --------
</TABLE>
 
- ------------------------------------------------
 
<TABLE>
<C>          <S>                                                 <C>
FORWARD FOREIGN CURRENCY EXCHANGE CONTRACT INFORMATION:
  Under the terms of forward foreign currency exchange contracts open at
  December 31, 1995, the Portfolio is obligated to deliver foreign
  currency in exchange for U.S. dollars as indicated below:
</TABLE>
 
<TABLE>
<CAPTION>
                                         IN
CURRENCY TO                           EXCHANGE                 UNREALIZED
  DELIVER      VALUE    SETTLEMENT      FOR        VALUE          LOSS
   (000)       (000)       DATE        (000)       (000)          (000)
- -----------  ---------  -----------  ----------  ---------  -----------------
<S>          <C>        <C>          <C>         <C>        <C>
JPY  9,167   $      89     1/04/96   U.S.$   89  $      89      $      --
NLG 10,090       6,305     2/23/96   U.S.$6,174      6,174           (131)
             ---------                           ---------          -----
             $   6,394                           $   6,263      $    (131)
             ---------                           ---------          -----
             ---------                           ---------          -----
</TABLE>
 
- ------------------------------------------------------------
 
<TABLE>
<S>        <C>        <C>
+             --      Non-income producing security
*             --      Restricted as to public resale. Total value of
                      restricted securities at December 31, 1995 was $127
                      or 0.1% of net assets. (Total cost $88)
**            --      Security is valued at fair value -- See Note A-1
CDI           --      Certificate of Investment
IDR           --      International Depositary Receipt
NCS           --      Non Convertible Shares
</TABLE>
 
- ------------------------------------------------------------
 
        SUMMARY OF FOREIGN & U.S. SECURITIES BY INDUSTRY CLASSIFICATION
 
<TABLE>
<CAPTION>
                           (UNAUDITED)
                                           VALUE     PERCENT OF
INDUSTRY                                   (000)     NET ASSETS
- -----------------------------------------------------------------
<S>                                      <C>        <C>
Capital Equipment......................  $  16,075        17.5%
Consumer Goods.........................     11,364        12.4
Energy.................................      5,725         6.2
Finance................................     16,017        17.5
Materials..............................      7,645         8.3
Multi-Industry.........................      4,867         5.4
Services...............................     14,032        15.3
                                         ---------       ---
                                         $  75,725        82.6%
                                         ---------       ---
                                         ---------       ---
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                         Global Equity Portfolio
 
                                       33
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE GOLD PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
<C>          <S>                                                 <C>
- ------------------------------------------------------------
COMMON STOCKS (92.1%)
  AUSTRALIA (35.8%)
    +55,000  Acacia Resources Ltd. ............................  $     99
    +50,000  Delta Gold N.L. ..................................       121
    260,000  Gold Mines of Kalgoorlie Ltd. ....................       242
   +200,000  Great Central Mines N.L. .........................       386
     90,000  Newcrest Mining Ltd. .............................       379
    135,000  Plutonic Resources, Ltd. .........................       642
    275,000  Poseidon Gold Ltd. ...............................       548
   +225,000  Wiluna Mines Ltd. ................................       232
                                                                 --------
                                                                    2,649
                                                                 --------
  CANADA (24.5%)
   +169,600  Bema Gold Corp. ..................................       339
    +91,100  Bolivar Goldfields Ltd. ..........................        50
     +9,000  Bre-X Minerals, Ltd. .............................       349
    +97,000  Dakota Mining Corp. ..............................       146
     20,000  Glamis Gold Ltd. .................................       125
     11,400  Placer Dome, Inc. ................................       275
   +100,000  Royal Oak Mines, Inc. ............................       356
    +25,000  TVX Gold, Inc. ...................................       176
                                                                 --------
                                                                    1,816
                                                                 --------
  SOUTH AFRICA (4.4%)
      6,000  Driefontein Consolidated Ltd., ADR................        74
     14,000  Free State Consolidated Gold Mines Ltd. ADR.......       101
      4,200  Kloof Gold Mining Co., Ltd. ADR...................        40
     17,500  Vaal Reefs Exploration & Mining Co., Ltd. ADR.....       112
                                                                 --------
                                                                      327
                                                                 --------
  UNITED STATES (27.4%)
      7,000  Freeport McMoRan Copper & Gold, Inc., Class B.....       197
    +30,000  Gold Reserve Corp. ...............................       169
     23,000  Homestake Mining Co. .............................       359
      6,000  Newmont Mining Corp. .............................       272
    +25,000  Pegasus Gold, Inc. ...............................       347
     20,000  Santa Fe Pacific Gold Corp. ......................       243
    +23,000  Stillwater Mining Co. ............................       442
                                                                 --------
                                                                    2,029
                                                                 --------
TOTAL COMMON STOCKS (Cost $7,147)..............................     6,821
                                                                 --------
</TABLE>
<TABLE>
<CAPTION>
  NO. OF
 WARRANTS
- -----------
<C>          <S>                                                 <C>
WARRANTS (0.0%)
  UNITED STATES (0.0%)
   +25,000   Gold Reserve Corp., expiring 3/96 (Cost $0).......         4
                                                                 --------
 
<CAPTION>
 
   FACE
  AMOUNT                                                          VALUE
   (000)                                                          (000)
<C>          <S>                                                 <C>
- ------------------------------------------------------------
CONVERTIBLE BONDS (2.9%)
  UNITED STATES (2.9%)
$     #250   Canyon Resources 6.00%, 6/01/98 (Cost $276).......  $    212
                                                                 --------
TOTAL FOREIGN & U.S. SECURITIES (95.0%) (Cost $7,423)..........     7,037
                                                                 --------
SHORT-TERM INVESTMENT (3.9%)
  REPURCHASE AGREEMENT (3.9%)
       287   The Chase Manhattan Bank, N.A., 5.35%, dated
               12/29/95, due 1/2/96, to be repurchased at $287,
               collateralized by $265 United States Treasury
               Bonds, 7.50%, due 11/15/01, valued at $294 (Cost
               $287)...........................................       287
                                                                 --------
TOTAL INVESTMENTS (98.9%) (Cost $7,710)........................     7,324
                                                                 --------
</TABLE>
 
<TABLE>
<S>                                                 <C>          <C>
OTHER ASSETS (1.7%)
  Cash............................................  $         1
  Receivable for Investments Sold.................          106
  Receivable from Investment Adviser..............           16
  Dividends Receivable............................            2
  Interest Receivable.............................            1       126
                                                          -----
LIABILITIES (-0.6%)
  Investment Sub-Advisory Fees Payable............           (7)
  Custodian Fees Payable..........................           (5)
  Administrative Fees Payable.....................           (2)
  Other Liabilities...............................          (27)      (41)
                                                          -----  --------
NET ASSETS (100%)..............................................  $  7,409
                                                                 --------
                                                                 --------
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 866,575 outstanding $.001 par value shares
  (authorized 500,000,000 shares)..............................     $8.55
                                                                 --------
                                                                 --------
</TABLE>
 
- ------------------------------------------------------------
 
<TABLE>
<S>                                                 <C>          <C>
FORWARD FOREIGN CURRENCY EXCHANGE CONTRACT INFORMATION:
  Under the terms of forward foreign currency exchange contracts open at
  December 31, 1995, the Portfolio is obligated to deliver foreign
  currency in exchange for U.S. dollars as indicated below:
</TABLE>
 
<TABLE>
<CAPTION>
  CURRENCY TO                                            IN EXCHANGE                      UNREALIZED
    DELIVER                                                  FOR                          GAIN (LOSS)
     (000)          VALUE (000)     SETTLEMENT DATE         (000)        VALUE (000)         (000)
- ---------------        -----        ----------------     -----------        -----        -------------
<S>                 <C>             <C>                  <C>             <C>             <C>
    AUD 56          $       42              1/02/96         U.S.$42      $       42      $         --
</TABLE>
 
- ------------------------------------------------
 
<TABLE>
<S>        <C>        <C>
+             --      Non-income producing security
#             --      144A Security -- Certain conditions for public sale
                      may exist.
ADR           --      American Depositary Receipt
</TABLE>
 
- ------------------------------------------------
 
        SUMMARY OF FOREIGN & U.S. SECURITIES BY INDUSTRY CLASSIFICATION
                                  (UNAUDITED)
 
<TABLE>
<CAPTION>
                                           VALUE     PERCENT OF
INDUSTRY                                   (000)     NET ASSETS
<S>                                      <C>        <C>
- -----------------------------------------------------------------
Gold Mines.............................  $   7,037        95.0%
                                         ---------       -----
                                         ---------       -----
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Gold Portfolio
 
                                       36
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE INTERNATIONAL EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                   VALUE
  SHARES                                                           (000)
       ------------------------------------------------------------
<C>          <S>                                                 <C>
COMMON STOCKS (88.4%)
  AUSTRALIA (4.6%)
  3,535,000  Brambles Industries Ltd...........................  $   39,411
  5,069,000  CSR Ltd...........................................      16,502
   +402,000  McPherson's Ltd...................................          57
  3,934,882  Westpac Banking Corp..............................      17,430
                                                                 ----------
                                                                     73,400
                                                                 ----------
  BELGIUM (1.1%)
    +52,500  Arbed S.A.........................................       5,940
    254,000  G.I.B. Holdings Ltd...............................      11,151
      2,156  G.I.B. Holdings Ltd. (New)........................          92
                                                                 ----------
                                                                     17,183
                                                                 ----------
  DENMARK (1.8%)
     88,000  Novo-Nordisk A/S, Class B.........................      12,036
    350,000  Unidanmark A/S, Class A (Registered)..............      17,321
                                                                 ----------
                                                                     29,357
                                                                 ----------
  FINLAND (1.2%)
    350,000  Huhtamaki Oy, Series 1............................       8,449
   +168,467  Merita, Ltd., Class A.............................         426
    215,000  Nokia AB Oy, Series A.............................       8,453
    125,200  Pohjola Insurance Co., Ltd., Class B..............       1,612
                                                                 ----------
                                                                     18,940
                                                                 ----------
  FRANCE (7.2%)
    249,500  Banque Nationale de Paris.........................      11,255
     13,495  Bongrain S.A......................................       7,606
    133,000  Cie de Saint Gobain...............................      14,720
     17,300  Cie Financiere de Paribas S.A., Class A...........         949
   +153,050  Credit Lyonnaise CDI..............................       7,345
    246,975  Elf Aquitaine.....................................      18,197
    119,100  Peugeot S.A.......................................      15,711
    420,300  Thomson CSF S.A...................................       9,364
    230,644  Total S.A., Class B...............................      15,565
    324,045  Valeo S.A.........................................      15,008
                                                                 ----------
                                                                    115,720
                                                                 ----------
  GERMANY (10.8%)
    110,000  BASF AG...........................................      24,779
    105,000  Bayer AG..........................................      27,885
     50,000  Commerzbank AG....................................      11,873
     28,750  Hoechst AG........................................       7,820
     85,500  Karstadt AG.......................................      35,061
     73,125  Mannesmann AG.....................................      23,280
    +24,900  Varta AG..........................................       4,775
   +580,000  Veba AG...........................................      24,836
     37,500  Volkswagen AG.....................................      12,579
                                                                 ----------
                                                                    172,888
                                                                 ----------
  HONG KONG (0.6%)
   **90,600  China Light & Power Co., Ltd......................         410
  5,375,500  Hong Kong Land Holdings Ltd.......................       9,945
                                                                 ----------
                                                                     10,355
                                                                 ----------
 
<CAPTION>
                                                                   VALUE
  SHARES                                                           (000)
       ------------------------------------------------------------
<C>          <S>                                                 <C>
  ITALY (2.2%)
 +3,120,000  Olivetti Di Risp..................................  $    2,501
 +2,560,500  Olivetti Di Risp (NCS)............................       1,301
 +1,297,317  SME Meridonale....................................       2,651
  9,000,000  Stet Di Risp (NCS)................................      18,360
  4,720,000  Telecom Italia S.p.A..............................       7,340
  2,655,000  Telecom Italia S.p.A. Di Risp (NCS)...............       3,246
                                                                 ----------
                                                                     35,399
                                                                 ----------
  JAPAN (24.1%)
  1,050,000  Aisin Seiki Co., Ltd..............................      13,831
  1,000,000  Canon, Inc........................................      18,111
    115,000  Chudenko Corp.....................................       3,943
  1,345,000  Daibiru Corp......................................      15,241
  1,465,000  Daicel Chemical Industry Ltd......................       8,329
    660,000  Daikin Industries Ltd.............................       6,456
  1,037,000  Dainippon Ink & Chemical, Inc.....................       4,831
      3,600  East Japan Railway Co.............................      17,503
  2,150,000  Fuji Photo Film Ltd...............................      62,053
  2,700,000  Hitachi Ltd.......................................      27,196
  2,100,000  Kao Corp..........................................      26,034
    650,000  Kirin Brewery Co., Ltd............................       7,680
  1,700,000  Matsushita Electric Industries Ltd................      27,661
     81,000  Murata Manufacturing Co., Ltd.....................       2,981
  2,400,000  Nichido Fire & Marine Insurance Co., Ltd..........      19,293
      1,836  Nippon Telegraph & Telephone Corp.................      14,848
    221,000  Ryosan Co.........................................       6,079
    350,000  Sony Corp.........................................      20,983
  1,080,000  Stanley Electric Co...............................       6,485
  1,450,000  Sumitomo Marine & Fire Insurance Co...............      11,909
  3,000,000  Sumitomo Rubber Industries........................      25,046
    298,000  TDK Corp..........................................      15,210
    742,000  Toyo Seikan Kaisha Ltd............................      22,206
     37,150  Yurtec Corp.......................................         651
                                                                 ----------
                                                                    384,560
                                                                 ----------
  NETHERLANDS (9.3%)
    705,168  ABN Amro Holdings N.V.............................      32,123
    112,500  Akzo Nobel N.V....................................      13,012
     81,059  Hollandsche Beton Groep N.V.......................      12,376
    575,744  Internationale Nederlanden Groep N.V..............      38,462
    247,500  Koninklijke Bijenkorf Beheer N.V..................      16,349
    153,050  Nedlloyd Groep N.V................................       3,472
    773,000  Philips Electronics N.V...........................      27,938
     39,415  Unilever N.V. (Certificate).......................       5,539
                                                                 ----------
                                                                    149,271
                                                                 ----------
  NEW ZEALAND (0.4%)
  2,144,627  Fisher & Paykel Industries Ltd....................       6,520
 +**392,500  Smith City Group Ltd..............................          --
                                                                 ----------
                                                                      6,520
                                                                 ----------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                  International Equity Portfolio
 
                                       43
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE INTERNATIONAL EQUITY PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                   VALUE
  SHARES                                                           (000)
       ------------------------------------------------------------
<C>          <S>                                                 <C>
  NORWAY (1.4%)
  3,180,000  Den Norske Bank A/S,..............................  $    8,341
    573,800  Hafslund Nycomed, Class B.........................      14,551
                                                                 ----------
                                                                     22,892
                                                                 ----------
  SINGAPORE (2.1%)
  9,950,000  Jardine Strategic Holdings, Inc...................      30,447
  3,265,000  Neptune Orient Lines Ltd. (Foreign)...............       3,670
                                                                 ----------
                                                                     34,117
                                                                 ----------
  SPAIN (3.8%)
   +297,500  Grupo Duro Felguera S.A...........................       1,050
  2,345,000  Iberdrola S.A.....................................      21,459
  2,710,000  Telefonica Nacional de Espana S.A.................      37,533
                                                                 ----------
                                                                     60,042
                                                                 ----------
  SWEDEN (3.0%)
     28,600  Electrolux AB, Series B...........................       1,174
   +350,000  Nordbanken AB.....................................       6,062
  2,400,000  Skandinaviska Enskilda Banken, Class A............      19,881
    660,600  S.K.F. AB, Class B................................      12,636
    511,300  Svenska Cellulosa AB, Class B.....................       7,931
                                                                 ----------
                                                                     47,684
                                                                 ----------
  SWITZERLAND (5.9%)
     +2,605  Ascom Holdings AG (Bearer)........................       2,654
     25,008  Ciba-Geigy AG (Registered)........................      22,005
     16,000  Forbo Holding AG (Registered).....................       6,838
     33,000  Nestle S.A. (Registered)..........................      36,505
      2,410  Schindler Holding AG (Participating
               Certificates)...................................       2,496
     15,550  Sulzer AG (Participating Certificates)............       8,291
     12,500  Sulzer AG (Registered)............................       7,152
    +10,815  SwissAir (Registered).............................       7,876
                                                                 ----------
                                                                     93,817
                                                                 ----------
  UNITED KINGDOM (8.9%)
  1,260,000  Associated British Foods plc......................       7,218
  1,360,104  Automated Security Holdings plc...................         570
  4,905,000  Christian Salvesen plc............................      20,142
  1,487,721  Forte plc.........................................       7,634
  2,524,100  Grand Metropolitan plc............................      18,183
  4,841,985  John Mowlem & Co. plc.............................       4,473
  1,624,000  Kwik Save Group plc...............................      12,707
    843,000  McAlpine (Alfred) plc.............................       1,937
 +1,417,095  Pilkington plc....................................       4,444
  1,470,645  Reckitt & Colman plc..............................      16,279
  2,885,064  Rolls-Royce plc...................................       8,466
  1,429,956  Royal Insurance Holdings plc......................       8,480
    755,000  Unilever plc......................................      15,507
  6,145,000  WPP Group plc.....................................      15,646
                                                                 ----------
                                                                    141,686
                                                                 ----------
TOTAL COMMON STOCKS (Cost $1,152,875)..........................   1,413,831
                                                                 ----------
<CAPTION>
                                                                   VALUE
  SHARES                                                           (000)
       ------------------------------------------------------------
<C>          <S>                                                 <C>
 
PREFERRED STOCKS (3.7%)
  GERMANY (3.7%)
     +5,200  Fag Kugelficsher AG...............................  $      646
     77,700  RWE AG............................................      21,675
     29,525  Spar Handels AG...................................       6,342
    125,000  Volkswagen AG.....................................      30,319
                                                                 ----------
TOTAL PREFERRED STOCKS (Cost $46,959)..........................      58,982
                                                                 ----------
CONVERTIBLE PREFERRED SECURITIES (0.1%)
  HONG KONG (0.1%)
  1,863,000  Jardine Strategic Holdings, Inc. IDR, 7.50%,
               5/07/97.........................................       2,012
                                                                 ----------
  NETHERLANDS (0.0%)
      1,506  ABN Amro Holdings N.V.............................           6
      2,196  International Nederlanden Groep N.V...............          12
                                                                 ----------
                                                                         18
                                                                 ----------
TOTAL CONVERTIBLE PREFERRED SECURITIES (Cost $1,923)...........       2,030
                                                                 ----------
<CAPTION>
 
  NO. OF
  RIGHTS
- -----------
<C>          <S>                                                 <C>
RIGHTS (0.1%)
  UNITED KINGDOM (0.1%)
   +354,273  Pilkington plc (Cost $843)........................       1,100
                                                                 ----------
TOTAL FOREIGN SECURITIES (92.3%) (Cost $1,202,600).............   1,475,943
                                                                 ----------
<CAPTION>
 
   FACE
  AMOUNT
   (000)
- -----------
<C>          <S>                                                 <C>
SHORT-TERM INVESTMENT (3.9%)
  REPURCHASE AGREEMENT (3.9%)
$      62,548 The Chase Manhattan Bank, N.A., 5.35%, dated
               12/29/95, due 1/02/96, to be repurchased at
               $62,585, collateralized by $40,380 United States
               Treasury Bonds, 12.00%, due 8/15/13, valued at
               $63,800 (Cost $62,548)..........................      62,548
                                                                 ----------
FOREIGN CURRENCY (3.4%)
AUD          3  Australian Dollar..............................           3
GBP     14,074  British Pound..................................      21,850
DEM     14,857  Deutsche Mark..................................      10,361
FIM     22,998  Finnish Markka.................................       5,288
HKD          3  Hong Kong Dollar...............................          --
ITL        174  Italian Lira...................................          --
JPY  1,595,171  Japanese Yen...................................      15,450
NLG         44  Netherlands Guilder............................          27
ESP         19  Spanish Peseta.................................          --
SEK      2,753  Swedish Krona..................................         415
                                                                 ----------
TOTAL FOREIGN CURRENCY (Cost $53,560)..........................      53,394
                                                                 ----------
TOTAL INVESTMENTS (99.6%) (Cost $1,318,708)....................   1,591,885
                                                                 ----------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
International Equity Portfolio
 
                                       44
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE INTERNATIONAL EQUITY PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                   AMOUNT
                                                                   (000)
<S>                                                 <C>          <C>
       ------------------------------------------------------------
OTHER ASSETS (1.9%)
  Receivable for Portfolio Shares Sold............  $    21,040
  Net Unrealized Gain on Forward Foreign Currency
    Exchange Contracts............................        3,637
  Receivable for Investments Sold.................        2,910
  Dividends Receivable............................        1,499
  Foreign Withholding Tax Reclaim Receivable......        1,136
  Interest Receivable.............................           28
  Other...........................................          103  $   30,353
                                                    -----------
LIABILITIES (-1.5%)
  Payable for Portfolio Shares Redeemed...........      (10,574)
  Payable for Investments Purchased...............       (9,689)
  Investment Advisory Fees Payable................       (2,986)
  Administrative Fees Payable.....................         (203)
  Custodian Fees Payable..........................         (143)
  Other Liabilities...............................         (113)    (23,708)
                                                    -----------  ----------
NET ASSETS (100%)..............................................  $1,598,530
                                                                 ----------
                                                                 ----------
</TABLE>
 
<TABLE>
<C>          <S>                                                 <C>
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 105,547,323 outstanding $.001 par value shares
  (authorized 500,000,000 shares)..............................      $15.15
                                                                 ----------
                                                                 ----------
 
FORWARD FOREIGN CURRENCY EXCHANGE CONTRACT INFORMATION:
  Under the terms of forward foreign currency exchange contracts open at
  December 31, 1995, the Portfolio is obligated to deliver or is to receive
  foreign currency in exchange for U.S. dollars or foreign currency as
  indicated below:
</TABLE>
 
<TABLE>
<CAPTION>
                                                                      NET
                                                IN                 UNREALIZED
     CURRENCY                                EXCHANGE                 GAIN
    TO DELIVER       VALUE    SETTLEMENT        FOR        VALUE     (LOSS)
      (000)          (000)       DATE          (000)       (000)     (000)
- ------------------  --------  -----------  ------------  --------  ---------
<S>                 <C>       <C>          <C>           <C>       <C>
    FIM      1,602  $    368     1/02/96   DEM      526  $    366  $      (2)
    SGD        354       251     1/04/96   U.S.$    251       251         --
    U.S.$      251       251     1/04/96   SGD      354       251         --
    SGD        394       278     1/05/96   U.S.$    278       278         --
    DEM     95,500    66,730     3/01/96   U.S.$ 66,193    66,193       (537)
    DEM     40,000    28,160     8/09/96   U.S.$ 28,751    28,751        591
    FRF    153,000    31,289    10/11/96   U.S.$ 30,551    30,551       (738)
    JPY  5,801,100    58,287    10/11/96   U.S.$ 61,000    61,000      2,713
    NLG    118,000    74,654    11/14/96   U.S.$ 76,106    76,106      1,452
    ESP  5,400,000    43,036    12/02/96   U.S.$ 42,584    42,584       (452)
    JPY  3,100,000    31,341    12/24/96   U.S.$ 31,951    31,951        610
                    --------                             --------  ---------
                    $334,645                             $338,282  $   3,637
                    --------                             --------  ---------
                    --------                             --------  ---------
</TABLE>
 
- ------------------------------------------------------------
 
<TABLE>
<S>        <C>        <C>
+             --      Non-income producing security
**            --      Security is valued at fair value -- See Note A-1
CDI           --      Certificate of Investment
IDR           --      International Depositary Receipt
NCS           --      Non Convertible Shares
FRF           --      French Franc
SGD           --      Singapore Dollar
</TABLE>
 
- ------------------------------------------------------------
 
            SUMMARY OF FOREIGN SECURITIES BY INDUSTRY CLASSIFICATION
                                  (UNAUDITED)
 
<TABLE>
<CAPTION>
                                      VALUE        PERCENT
INDUSTRY                              (000)     OF NET ASSETS
<S>                                 <C>        <C>
- ---------------------------------------------------------------
Capital Equipment.................  $ 312,212          19.5%
Consumer Goods....................    385,335          24.1
Energy............................     80,467           5.0
Finance...........................    224,994          14.1
Materials.........................    195,044          12.2
Multi-Industry....................     61,125           3.8
Services..........................    216,766          13.6
                                    ---------           ---
                                    $1,475,943         92.3%
                                    ---------           ---
                                    ---------           ---
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                  International Equity Portfolio
 
                                       45
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE INTERNATIONAL SMALL CAP PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                    VALUE
   SHARES                                                           (000)
<C>           <S>                                                 <C>
                ------------------------------------------------------------
COMMON STOCKS (93.9%)
  AUSTRALIA (7.9%)
      92,344  Arnotts Ltd.......................................  $      618
     564,678  Auspine Ltd.......................................       1,645
    +990,079  Bains Harding Ltd.................................         316
   1,566,167  BRL Hardy Ltd.....................................       2,503
     140,833  BRL Hardy Ltd. (New)..............................         225
   1,100,000  Burswood Property Trust...........................       1,472
   2,351,732  Country Road Ltd..................................       3,059
   2,186,801  E.R.G. Ltd........................................       2,617
    +467,800  McPherson's Ltd...................................          66
   5,638,088  Parbury Ltd.......................................       2,179
   1,721,500  Solution 6 Holdings Ltd...........................       1,024
                                                                  ----------
                                                                      15,724
                                                                  ----------
  DENMARK (1.8%)
    +107,000  SYD-Sonderjylland Holdings........................       3,466
                                                                  ----------
  FINLAND (2.7%)
     125,000  Amer-Yhtymae Oy, Class A..........................       1,951
     180,000  Hartwall Oy, Class A..............................       3,352
                                                                  ----------
                                                                       5,303
                                                                  ----------
  FRANCE (8.2%)
      72,000  Dauphin O.T.A.....................................       2,941
      54,000  De Dietrich et Compagnie..........................       2,371
      31,150  Europeene de Propulsion S.A.......................       2,125
       8,100  Galeries Layfayette...............................       1,975
     +17,700  Legris Industries S.A.............................         576
      24,500  Precision Mecaniques Labinal S.A..................       2,717
      91,756  Sediver S.A.......................................       3,560
                                                                  ----------
                                                                      16,265
                                                                  ----------
  GERMANY (5.3%)
      13,000  Duerr Beteiligungs AG.............................       3,889
      10,688  Sinn AG...........................................       2,013
     +20,000  Varta AG..........................................       3,836
       2,210  Vossloh AG........................................         729
                                                                  ----------
                                                                      10,467
                                                                  ----------
  HONG KONG (1.9%)
     445,000  Jardine International Motor Holdings Ltd..........         506
  +5,200,000  Pico Far East Holdings Ltd........................         666
     780,000  Tungtex Holdings Co., Ltd.........................          80
   5,862,000  Vitasoy International Holdings Ltd................       2,502
                                                                  ----------
                                                                       3,754
                                                                  ----------
  IRELAND (2.0%)
   1,070,000  Avonmore Foods plc, Class A.......................       2,176
     692,472  Green Property plc................................       1,863
                                                                  ----------
                                                                       4,039
                                                                  ----------
  ITALY (2.4%)
  +1,172,800  Editoriale L'Expresso S.p.A.......................       2,031
    +754,000  Unicem Di Risp (NCS)..............................       1,913
      81,000  Vincenzo Zucchi S.p.A.............................         408
     212,500  Vincenzo Zucchi S.p.A. (NCS)......................         468
                                                                  ----------
                                                                       4,820
                                                                  ----------
 
<CAPTION>
                                                                    VALUE
   SHARES                                                           (000)
<C>           <S>                                                 <C>
                ------------------------------------------------------------
  JAPAN (12.7%)
      15,000  Exedy Corp........................................  $      238
     231,000  Foster Electric Co., Ltd..........................       1,425
    +175,000  Hankyu Realty.....................................       1,422
     707,000  Japan Oil Transportation..........................       4,451
     213,000  Japan Vilene Co., Ltd.............................       1,343
     134,000  Kansei Corp.......................................       1,085
     243,000  Kirin Beverage Corp...............................       3,272
     124,000  Nifco, Inc........................................       1,621
     335,000  Nissan Fire & Insurance Co........................       2,349
     549,000  Toc Co............................................       5,477
    +327,000  Tokai Senko K.K...................................       1,302
     170,000  Toyoda Gosei Co...................................       1,177
                                                                  ----------
                                                                      25,162
                                                                  ----------
  NETHERLANDS (6.9%)
     +62,600  Ahrend Groep N.V..................................       2,060
      26,800  Hollandsche Beton Groep N.V.......................       4,092
      28,885  Industriemij Welna N.V............................         837
     141,000  Koninklijke Van Ommeren N.V.......................       4,393
      36,000  Konin Nijverdal -- Ten Carte N.V..................       1,519
       8,802  Polynorm N.V......................................         751
                                                                  ----------
                                                                      13,652
                                                                  ----------
  NEW ZEALAND (2.0%)
     659,729  Fisher & Paykel Industries Ltd....................       2,005
   1,634,800  Whitcoulls Group Ltd..............................       2,031
                                                                  ----------
                                                                       4,036
                                                                  ----------
  NORWAY (0.8%)
      11,500  Adelsten, Class B.................................       1,136
    +228,020  Oceanor...........................................         522
                                                                  ----------
                                                                       1,658
                                                                  ----------
  SPAIN (5.2%)
    +346,000  Asturiana del Zinc S.A............................       2,744
      92,840  Bodegas y Bebidas S.A.............................       2,373
      92,770  Gas y Electricidad S.A............................       5,193
                                                                  ----------
                                                                      10,310
                                                                  ----------
  SWITZERLAND (16.9%)
       3,715  Bobst AG (Bearer).................................       5,797
       4,965  Bucher Holdings AG (Bearer).......................       2,841
       9,800  Edipresse S.A. (Bearer)...........................       2,634
       7,400  Elco Looser Holding AG (Registered)...............       3,015
       3,400  Hero AG (Bearer)..................................       1,680
         995  Kouni Reisen Holdings, Class B (Registered).......       1,596
       2,750  LEM Holdings AG...................................         970
       7,035  Magazine Globus (Participating Certificates)......       4,025
       5,850  Porst Holding AG (Bearer).........................       1,009
         590  Schweizerische Industrie-Gesellschaft Holdings
                (Bearer)........................................       1,233
       4,400  Schweizerische Industrie-Gesellschaft Holdings
                (Registered)....................................       4,463
      +4,250  Von Moos Holding AG (Bearer)......................         350
      +4,160  Zellweger Luwa AG (Bearer)........................       4,057
                                                                  ----------
                                                                      33,670
                                                                  ----------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
International Small Cap Portfolio
 
                                       48
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE INTERNATIONAL SMALL CAP PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                    VALUE
   SHARES                                                           (000)
                ------------------------------------------------------------
<C>           <S>                                                 <C>
  UNITED KINGDOM (17.2%)
   4,502,198  Anglo Irish Bank Corp. plc (British Pound
                Shares).........................................  $    4,438
    +559,500  Asprey plc........................................       2,172
      31,700  Bespak plc........................................         155
    +895,000  Blagden Industries plc............................       1,987
     584,000  Bluebird Toys plc.................................       2,919
   1,266,800  BSM Group plc.....................................       3,048
     214,300  Church & Co. plc..................................       1,211
+**2,540,850  Donelon Tyson plc.................................          --
   1,895,000  EFG plc...........................................         427
     952,000  GEI International plc.............................       1,774
     212,000  Hadleigh Industries Group plc.....................         599
   2,340,000  Hobson plc........................................       1,090
     390,000  Hornby Group plc..................................         951
     223,000  International Business Communications (Holdings)
                plc.............................................         990
     877,294  John Mowlem & Co. plc.............................         810
  35,365,100  Kendell plc.......................................         549
     206,335  Mallett plc.......................................         266
   2,662,000  Matthews (Bernard) plc............................       3,926
     157,500  Oriflame International S.A........................         995
+**2,659,393  Pentos plc........................................          --
     345,526  Perry Group plc...................................         783
   1,600,000  Shandwick plc.....................................         907
      72,000  Sketchley plc.....................................         141
     800,000  The 600 Group plc.................................       1,950
     275,000  Tibbett & Britten Group plc.......................       1,742
     541,700  Waterman Partnership Holdings plc.................         336
                                                                  ----------
                                                                      34,166
                                                                  ----------
TOTAL COMMON STOCKS (Cost $193,194).............................     186,492
                                                                  ----------
PREFERRED STOCKS (3.8%)
  GERMANY (3.8%)
      59,900  Berentzen-Gruppe AG...............................       1,901
       1,800  Jil Sander AG.....................................       1,324
       7,745  Shaerf AG.........................................       1,053
      10,550  Spar Handels AG...................................       2,266
       5,410  Wuerttembergische Metallwarenfabrik AG............       1,098
                                                                  ----------
TOTAL PREFERRED STOCKS (Cost $8,320)............................       7,642
                                                                  ----------
<CAPTION>
 
   NO. OF
  WARRANTS
- ------------
<C>           <S>                                                 <C>
WARRANTS (0.0%)
  HONG KONG (0.0%)
    +452,000  Pico Far East Holdings Ltd., expiring 4/30/96.....           2
                                                                  ----------
  SWITZERLAND (0.0%)
      +4,600  Zellweger Luwa AG, expiring 5/21/97...............          44
                                                                  ----------
TOTAL WARRANTS (Cost $68).......................................          46
                                                                  ----------
<CAPTION>
 
    FACE
   AMOUNT                                                           VALUE
   (000)                                                            (000)
<C>           <S>                                                 <C>
                ------------------------------------------------------------
CONVERTIBLE DEBENTURE (0.2%)
  ITALY (0.2%)
 ITL 518,000  Mediobanca S.p.A. 5.50%, 1/01/00
                (Cost $329).....................................  $      285
                                                                  ----------
TOTAL FOREIGN SECURITIES (97.9%) (Cost $201,911)................     194,465
                                                                  ----------
SHORT-TERM INVESTMENT (0.2%)
  REPURCHASE AGREEMENT (0.2%)
 $       337  The Chase Manhattan Bank, N.A., 5.35%, dated
                12/29/95, due 1/02/96, to be repurchased at
                $337, collateralized by $337 United States
                Treasury Bonds, 8.875%, due 8/15/17, valued at
                $348 (Cost $337)................................         337
                                                                  ----------
FOREIGN CURRENCY (3.1%)
AUD    145  Australian Dollar...................................         108
GBP  1,147  British Pound.......................................       1,781
DEM  6,156  Deutsche Mark.......................................       4,293
HKD    359  Hong Kong Dollar....................................          46
JPY      9  Japanese Yen........................................          --
NZD     63  New Zealand Dollar..................................          41
                                                                  ----------
TOTAL FOREIGN CURRENCY (Cost $6,246)............................       6,269
                                                                  ----------
TOTAL INVESTMENTS (101.2%) (Cost $208,494)......................     201,071
                                                                  ----------
</TABLE>
 
<TABLE>
<S>                                                 <C>           <C>
OTHER ASSETS (0.7%)
  Receivable for Investments Sold.................  $        820
  Receivable for Portfolio Shares Sold............           225
  Dividends Receivable............................           209
  Foreign Withholding Tax Reclaim Receivable......           199
  Interest Receivable.............................            16
  Other...........................................            12       1,481
                                                    ------------
LIABILITIES (-1.9%)
  Payable for Investments Purchased...............        (1,492)
  Net Unrealized Loss on Forward Foreign Currency
    Exchange Contracts............................          (933)
  Payable for Portfolio Shares Redeemed...........          (882)
  Investment Advisory Fees Payable................          (440)
  Custodian Fees Payable..........................           (31)
  Bank Overdraft..................................           (29)
  Administrative Fees Payable.....................           (27)
  Other Liabilities...............................           (49)     (3,883)
                                                    ------------  ----------
NET ASSETS (100%)...............................................  $  198,669
                                                                  ----------
                                                                  ----------
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 13,299,989 outstanding $.001 par
  value shares (authorized 1,000,000,000
  shares).........................................                    $14.94
                                                                  ----------
                                                                  ----------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                               International Small Cap Portfolio
 
                                       49
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE INTERNATIONAL SMALL CAP PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<S>                                                 <C>           <C>
FORWARD FOREIGN CURRENCY EXCHANGE CONTRACT INFORMATION:
  Under the terms of forward foreign currency exchange contracts open at
  December 31, 1995, the Portfolio is obligated to deliver or is to receive
  foreign currency in exchange for U.S. dollars or foreign currency as
  indicated below:
</TABLE>
 
<TABLE>
<CAPTION>
                                         IN                       NET
 CURRENCY                             EXCHANGE                UNREALIZED
TO DELIVER     VALUE    SETTLEMENT      FOR         VALUE     GAIN (LOSS)
   (000)       (000)       DATE        (000)        (000)        (000)
- -----------  ---------  ----------  ------------  ---------  -------------
<C>          <C>        <C>         <S>           <C>        <C>
AUD     388  $     289   1/03/96    U.S.$    289  $     289           --
DEM     587        410   1/04/96    JPY   42,205        409           (1)
CHF   8,750      7,636   3/04/96    U.S.$  7,204      7,204         (432)
DEM  10,300      7,198   3/04/96    U.S.$  7,099      7,099          (99)
ESP 675,000      5,521   3/04/96    U.S.$  5,107      5,107         (414)
JPY 798,840      8,026   10/11/96   U.S.$  8,400      8,400          374
U.S.$ 8,400      8,400   10/11/96   JPY  800,100      8,039         (361)
             ---------                            ---------        -----
             $  37,480                            $  36,547    $    (933)
             ---------                            ---------        -----
             ---------                            ---------        -----
</TABLE>
 
- ------------------------------------------------------------
 
<TABLE>
<S>        <C>        <C>
+             --      Non-income producing security
**            --      Security is valued at fair value -- See Note A-1
NCS           --      Non Convertible Shares
CHF           --      Swiss Franc
ESP           --      Spanish Peseta
ITL           --      Italian Lira
</TABLE>
 
- ------------------------------------------------------------
 
            SUMMARY OF FOREIGN SECURITIES BY INDUSTRY CLASSIFICATION
                                  (UNAUDITED)
 
<TABLE>
<CAPTION>
                                          VALUE     PERCENT OF
INDUSTRY                                  (000)     NET ASSETS
<S>                                     <C>        <C>
- ----------------------------------------------------------------
Capital Equipment.....................  $  47,307        23.8%
Consumer Goods........................     49,238        24.8
Energy................................      7,937         4.0
Finance...............................     20,583        10.4
Materials.............................     20,257        10.2
Multi-Industry........................      3,540         1.8
Services..............................     45,603        22.9
                                        ---------       -----
                                        $ 194,465        97.9%
                                        ---------       -----
                                        ---------       -----
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
International Small Cap Portfolio
 
                                       50
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE JAPANESE EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
<C>         <S>                                                 <C>
- ------------------------------------------------------------
COMMON STOCKS (89.9%)
  CAPITAL EQUIPMENT (31.1%)
   240,000  Amada Co., Ltd....................................  $    2,371
   132,000  Dai Nippon Printing Co., Ltd......................       2,237
   136,000  Daifuku...........................................       1,923
   146,000  Daikin Industries Ltd.............................       1,428
    77,000  Fuji Machine Manufacturing Co.....................       2,759
    80,000  Kurita Water Industries...........................       2,131
    39,000  Kyocera Ltd.......................................       2,897
    90,000  Kyudenko Co., Ltd.................................       1,185
    60,000  Matsui Construction...............................         467
    80,000  Matsushita Communication Industries...............       1,860
   360,000  Mitsubishi Heavy Industries Ltd...................       2,870
    67,000  Nifco, Inc........................................         876
    80,000  Nippon Pillar Packing.............................       1,023
   294,000  Obayashi Corp.....................................       2,335
   240,000  Ricoh Co., Ltd....................................       2,626
   300,000  Taisei Corp., Ltd.................................       2,001
   260,000  Teijin Seiki Co., Ltd.............................       1,334
    62,000  Tokyo Electron Ltd................................       2,402
    60,000  Toshiba Engineering & Construction................         494
   320,000  Tsubakimoto Chain.................................       1,925
                                                                ----------
                                                                    37,144
                                                                ----------
  CONSUMER GOODS (14.9%)
   113,000  Canon, Inc........................................       2,047
    79,000  Fuji Photo Film Ltd...............................       2,280
   131,000  Japan Vilene Co., Ltd.............................         826
    37,000  Nintendo Corp., Ltd...............................       2,813
   278,000  Nissan Motor Co...................................       2,135
    71,000  Sankyo Co., Ltd...................................       1,595
    37,000  Shimamura Co., Ltd................................       1,430
   230,000  Suzuki Motor Co., Ltd.............................       2,562
    95,000  Yamanouchi Pharmaceutical Co......................       2,042
                                                                ----------
                                                                    17,730
                                                                ----------
  ELECTRICAL & ELECTRONICS (18.4%)
    70,000  CMK...............................................         997
   344,000  Hitachi Ltd.......................................       3,465
   187,000  Matsushita Electric Industries Ltd................       3,043
    85,000  Mitsumi Electric Co., Ltd.........................       2,050
   294,000  NEC Corp..........................................       3,588
    28,000  Sony Corp.........................................       1,679
   235,000  Stanley Electric Co...............................       1,411
    40,000  TDK Corp..........................................       2,042
   464,000  Toshiba Corp......................................       3,636
                                                                ----------
                                                                    21,911
                                                                ----------
  FINANCE (6.4%)
   180,000  Daiwa Securities Co., Ltd.........................       2,754
    77,000  Hitachi Credit Corp...............................       1,395
    50,000  Nichido Fire & Marine Insurance Co., Ltd..........         402
   131,000  Nomura Securities Co..............................       2,855
    43,000  Sumitomo Corp. Leasing Ltd........................         221
                                                                ----------
                                                                     7,627
                                                                ----------
  MATERIALS (7.4%)
   171,000  Asahi Tec Corp....................................       1,136
   298,000  Daicel Chemical Industry Ltd......................       1,694
 
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
<C>         <S>                                                 <C>
- ------------------------------------------------------------
   226,000  Kaneka Corp.......................................  $    1,425
    60,000  Kansei Corp.......................................         486
   128,000  Okura Industrial Co., Ltd.........................         874
   155,000  Sanwa Shutter.....................................       1,124
   142,000  Sekisui Chemical Co...............................       2,091
                                                                ----------
                                                                     8,830
                                                                ----------
  MULTI-INDUSTRY (1.5%)
    40,100  FamilyMart........................................       1,810
                                                                ----------
  SERVICES (10.2%)
    82,000  Daibiru Corp......................................         930
   190,000  Inabata & Co......................................       1,343
   117,000  Keihanshin Real Estate............................         896
   146,000  Mitsubishi Estate Co., Ltd........................       1,824
   100,000  Nippon Konpo Unyu Soko............................         852
       269  Nippon Telegraph & Telephone Corp.................       2,175
    32,000  Nishio Rent All Co................................         738
    39,000  Sangetsu Co., Ltd.................................         982
    35,000  Secom Co., Ltd....................................       2,434
                                                                ----------
                                                                    12,174
                                                                ----------
TOTAL COMMON STOCKS (Cost $105,078)...........................     107,226
                                                                ----------
<CAPTION>
   FACE
  AMOUNT
  (000)
- ----------
<C>         <S>                                                 <C>
SHORT-TERM INVESTMENT (7.2%)
  REPURCHASE AGREEMENT (7.2%)
  $  8,601  The Chase Manhattan Bank, N.A., 5.35%, dated
              12/29/95, due 1/02/96, to be repurchased at
              $8,606, collateralized by $5,665 United States
              Treasury Bonds, 11.75%, due 11/15/14, valued at
              $8,774 (Cost $8,601)............................       8,601
                                                                ----------
FOREIGN CURRENCY (0.0%)
  JPY2,734  Japanese Yen (Cost $26)...........................          26
                                                                ----------
TOTAL INVESTMENTS (97.1%) (Cost $113,705).....................     115,853
                                                                ----------
</TABLE>
 
<TABLE>
<S>                                                 <C>         <C>
OTHER ASSETS (3.1%)
  Net Unrealized Gain on Forward Foreign Currency   $    3,571
   Exchange Contracts.............................
  Receivable for Portfolio Shares Sold............          67
  Dividends Receivable............................          20
  Interest Receivable.............................           4
  Other...........................................           4       3,666
                                                    ----------
LIABILITIES (-0.2%)
  Investment Advisory Fees Payable................        (165)
  Administrative Fees Payable.....................         (15)
  Custodian Fees Payable..........................         (12)
  Bank Overdraft..................................          (6)
  Other Liabilities...............................         (43)       (241)
                                                    ----------  ----------
NET ASSETS (100%).............................................  $  119,278
                                                                ----------
                                                                ----------
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 12,868,920 outstanding $.001 par value shares
  (authorized 500,000,000 shares).............................       $9.27
                                                                ----------
                                                                ----------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
- --------------------------------------------------------------------------------
                                                       Japanese Equity Portfolio
 
                                       53
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE JAPANESE EQUITY PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
 
FORWARD FOREIGN CURRENCY EXCHANGE CONTRACT INFORMATION:
    Under the terms of forward foreign currency exchange contracts open at
    December 31, 1995, the Portfolio is obligated to deliver foreign currency in
    exchange for U.S. dollars as indicated below:
 
<TABLE>
<CAPTION>
                                           IN                      NET
  CURRENCY                              EXCHANGE               UNREALIZED
 TO DELIVER      VALUE    SETTLEMENT       FOR        VALUE       GAIN
    (000)        (000)       DATE         (000)       (000)       (000)
- -------------  ---------  -----------  -----------  ---------  -----------
<S>            <C>        <C>          <C>          <C>        <C>
JPY 1,649,900  $  16,099     2/26/96   U.S.$17,500  $  17,500   $   1,401
JPY 2,064,876     20,162     2/29/96   U.S.$21,300     21,300       1,138
JPY 2,522,843     24,716     3/25/96   U.S.$25,500     25,500         784
JPY 1,350,000     13,332     5/22/96   U.S.$13,580     13,580         248
               ---------                            ---------  -----------
               $  74,309                            $  77,880   $   3,571
               ---------                            ---------  -----------
               ---------                            ---------  -----------
</TABLE>
 
- ------------------------------------------------------------
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
- --------------------------------------------------------------------------------
Japanese Equity Portfolio
 
                                       54
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE LATIN AMERICAN PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                            VALUE
     SHARES                                                                 (000)
<C>                <S>                                                 <C>
- ------------------------------------------------------------
COMMON STOCKS (62.9%)
  ARGENTINA (10.3%)
           4,030   Banco de Galicia Y Buenos Aires ADR...............  $             83
         144,371   Banco del Suquia, Class B.........................               195
           3,473   Banco Frances ADS.................................                93
         #19,575   Capex S.A. ADR....................................               286
           8,659   Quilmes Industrial S.A............................               135
           3,950   Telecom Argentina S.A. ADR........................               188
          22,215   Telefonica de Argentina S.A. ADR..................               606
                                                                                -------
                                                                                  1,586
                                                                                -------
  BRAZIL (20.2%)
      19,488,000   Cia Acos Especiais Itabira........................                92
        +#13,445   Cia Brasileira ADR................................               134
          #1,224   Cia Energetica de Minas Gerais ADR................                27
          #6,842   Cia Energetica de Minas Gerais GDR................               151
       2,295,000   Eletrobras........................................               621
         #27,650   Eletrobras ADR....................................               375
           1,400   Electrobras ADR, Class B..........................                19
         +#3,930   Lojas Americanas S.A. ADR.........................                33
       7,240,000   Refrigeracao Parana S.A...........................                13
          #6,845   Rhodia-Ster ADS...................................                62
         515,000   Servicos de Eletricidade..........................               165
       3,590,000   Telebras..........................................               139
         #25,320   Telebras ADR......................................             1,200
         538,500   Telecomunicacoes de Sao Paulo.....................                78
                                                                                -------
                                                                                  3,109
                                                                                -------
  COLOMBIA (0.5%)
         #15,330   Banco de Colombia GDR.............................                80
                                                                                -------
  MEXICO (31.9%)
          79,160   Apasco S.A., Class A..............................               325
         213,980   Banacci, Class B..................................               359
          52,329   Banacci, Class L..................................                78
         +23,950   Cemex CPO ADR.....................................               158
         149,248   Cemex S.A., Class A...............................               493
        +143,000   Cifra S.A. de C.V., Class B.......................               149
          24,160   Empresas ICA S.A. ADR.............................               248
         299,100   FEMSA, Class B....................................               674
         +#7,210   Grupo Carso S.A. ADR..............................                77
        #118,585   Grupo Financiero Bancomer ADR.....................               689
          13,270   Alfa S.A. de C.V., Class A........................               171
          15,070   Grupo Televisa S.A. ADR...........................               339
          11,870   Kimberly Clark de Mexico S.A. de C.V., Class A....               180
           8,185   Panamerican Beverages, Inc., Class A..............               262
          21,945   Telefonos de Mexico S.A. ADR, Class L.............               699
                                                                                -------
                                                                                  4,901
                                                                                -------
TOTAL COMMON STOCKS (Cost $9,082)....................................             9,676
                                                                                -------
 
<CAPTION>
                                                                            VALUE
     SHARES                                                                 (000)
<C>                <S>                                                 <C>
- ------------------------------------------------------------
PREFERRED (NON-VOTING STOCKS) (32.7%)
  BRAZIL (32.7%)
      65,136,249   Banco Bradesco S.A................................  $            570
     +19,913,000   Banco do Brasil...................................               225
    **11,847,000   Banco Nacional S.A................................                25
       1,892,173   Brahma............................................               779
        +148,500   Centrais Eletricas de Santa Catarina, Class B.....                72
      +4,811,000   Cia Energetica de Minas Gerais....................               107
       7,899,000   Cia Paulista de Forca E Luz.......................               211
       3,566,000   Continental 2001..................................                44
         479,000   Coteminas.........................................               160
        +189,211   Dixie Toga S.A....................................               165
       1,664,000   Eletrobras, Class B...............................               450
       1,126,400   Itaubanco.........................................               314
         151,000   Itausa Investimentos Itau S.A.....................                82
       8,180,000   Lojas Renner......................................               219
          63,000   Multibras S.A.....................................                47
       3,280,000   Petrobras.........................................               280
      38,295,000   Refrigeracao Parana S.A...........................                76
      15,109,000   Telebras..........................................               728
         551,000   Telecomunicacoes de Sao Paulo.....................                81
       1,518,000   Vale Do Rio Doce..................................               250
         329,000   WEG S.A...........................................               135
                                                                                -------
TOTAL PREFERRED (NON-VOTING STOCKS) (Cost $5,375)....................             5,020
                                                                                -------
<CAPTION>
 
      FACE
     AMOUNT
     (000)
- ----------------
<C>                <S>                                                 <C>
FIXED INCOME SECURITIES (4.8%)
  BONDS (2.1%)
    COLOMBIA (2.1%)
      $     #430   Banco de Colombia 5.20%, 2/01/99
                     (Cost $380).....................................               327
                                                                                -------
  CONVERTIBLE DEBENTURES (2.7%)
    VENEZUELA (2.7%)
             750   Republic of Venezuela Debt Conversion Bonds,
                     Series DL, (Floating Rate), 6.563%, 12/18/07
                     (Cost $394).....................................               413
                                                                                -------
TOTAL FIXED INCOME SECURITIES (Cost $774)............................               740
                                                                                -------
<CAPTION>
 
     NO. OF
     RIGHTS
- ----------------
<C>                <S>                                                 <C>
RIGHTS (0.0%)
  BRAZIL (0.0%)
    +**2,058,932   Banco Bradesco, expiring 1/31/96
                     (Cost $0).......................................                 3
                                                                                -------
TOTAL FOREIGN SECURITIES (100.4%) (Cost $15,231).....................            15,439
                                                                                -------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Latin American Portfolio
 
                                       58
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE LATIN AMERICAN PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
     AMOUNT                                                                 VALUE
     (000)                                                                  (000)
<C>                <S>                                                 <C>
- ------------------------------------------------------------
FOREIGN CURRENCY (0.2%)
ARP        7   Argentine Peso........................................  $              7
BRC        4   Brazilian Real........................................                 4
MXP      155   Mexican Peso..........................................                20
PSS        2   Peruvian New Sol......................................                 1
                                                                                -------
TOTAL FOREIGN CURRENCY (Cost $32)....................................                32
                                                                                -------
TOTAL INVESTMENTS (100.6%) (Cost $15,263)............................            15,471
                                                                                -------
</TABLE>
 
<TABLE>
<S>                                        <C>        <C>
OTHER ASSETS (4.1%)
  Receivable for Investments Sold........  $     581
  Dividends Receivable...................         42
  Interest Receivable....................         11
  Other..................................          1        635
                                           ---------
LIABILITIES (-4.7%)
  Bank Overdraft.........................       (415)
  Payable for Portfolio Shares
   Redeemed..............................       (237)
  Custodian Fees Payable.................        (29)
  Investment Advisory Fees Payable.......         (7)
  Sub-Administrative Fees Payable........         (5)
  Administrative Fees Payable............         (4)
  Other Liabilities......................        (33)      (730)
                                           ---------  ---------
NET ASSETS (100%)...................................  $  15,376
                                                      ---------
                                                      ---------
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 1,697,153 outstanding $.001 par
  value shares (authorized 500,000,000 shares)......      $9.06
                                                      ---------
                                                      ---------
</TABLE>
 
- ------------------------------------------------
+   -- Non-income producing security
**  -- Security is valued at fair value -- See Note A-1
#   -- 144A Security -- Certain conditions for public sale may exist.
ADR -- American Depositary Receipt
ADS -- American Depositary Shares
GDR -- Global Depositary Receipt
CPO -- Certificate of Participation
Floating Rate -- Interest rate changes on these instruments are based on changes
in a designated base rate. The rates shown are those in effect on December 31,
1995.
 
            SUMMARY OF FOREIGN SECURITIES BY INDUSTRY CLASSIFICATION
                                  (UNAUDITED)
 
<TABLE>
<CAPTION>
                                           VALUE     PERCENT OF
INDUSTRY                                   (000)     NET ASSETS
<S>                                      <C>        <C>
- -----------------------------------------------------------------
Capital Equipment......................  $     344          2.3%
Consumer Goods.........................      2,512         16.3
Energy.................................      2,881         18.7
Finance................................      3,124         20.3
Government.............................        413          2.7
Materials..............................      1,719         11.2
Multi-Industry.........................        389          2.5
Services...............................      4,057         26.4
                                         ---------      -------
                                         $  15,439        100.4%
                                         ---------      -------
                                         ---------      -------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                        Latin American Portfolio
 
                                       59
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE AGGRESSIVE EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
COMMON STOCKS (101.2%)
  CAPITAL GOODS/CONSTRUCTION (16.0%)
    AEROSPACE & DEFENSE (9.2%)
     8,900  General Dynamics Corp.............................  $      526
    10,200  McDonnell Douglas Corp............................         938
    12,300  United Technologies Corp..........................       1,167
                                                                ----------
                                                                     2,631
                                                                ----------
    BUILDING & CONSTRUCTION (2.8%)
    18,400  American Standard Co..............................         515
    19,900  AMRE, Inc.........................................         291
                                                                ----------
                                                                       806
                                                                ----------
    MACHINERY (4.0%)
    16,300  Sundstrand Corp...................................       1,147
                                                                ----------
  TOTAL CAPITAL GOODS/CONSTRUCTION............................       4,584
                                                                ----------
  CONSUMER CYCLICAL (14.4%)
    ENTERTAINMENT & LEISURE (2.4%)
     4,700  Eastman Kodak Co..................................         315
     6,400  Walt Disney Co....................................         378
                                                                ----------
                                                                       693
                                                                ----------
    FOOD SERVICE & LODGING (5.0%)
   +17,300  HFS, Inc..........................................       1,414
                                                                ----------
    PUBLISHING (1.8%)
    42,300  K-III Communications, Corp........................         513
                                                                ----------
    RETAIL-GENERAL (5.2%)
   +20,700  AutoZone, Inc.....................................         598
   +25,200  General Nutrition Cos., Inc.......................         580
     6,700  Home Depot, Inc...................................         321
                                                                ----------
                                                                     1,499
                                                                ----------
  TOTAL CONSUMER CYCLICAL.....................................       4,119
                                                                ----------
  CONSUMER STAPLES (30.8%)
    BEVERAGES & TOBACCO (2.9%)
    15,000  Coca Cola Enterprises, Inc........................         401
    13,800  RJR Nabisco Holdings Corp.........................         426
                                                                ----------
                                                                       827
                                                                ----------
    CIGARETTES (19.8%)
    59,400  Philip Morris Cos., Inc...........................       5,376
     8,400  UST, Inc..........................................         280
                                                                ----------
                                                                     5,656
                                                                ----------
    DRUGS (5.0%)
    16,200  Pharmacia & Upjohn, Inc...........................         628
    14,600  Schering-Plough Corp..............................         799
                                                                ----------
                                                                     1,427
                                                                ----------
 
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
    FOOD (3.1%)
    12,000  Ralston Purina Group..............................  $      749
     2,700  Wrigley (William) Jr. Co..........................         142
                                                                ----------
                                                                       891
                                                                ----------
  TOTAL CONSUMER STAPLES......................................       8,801
                                                                ----------
  DIVERSIFIED (4.1%)
    14,900  Loews Corp........................................       1,168
                                                                ----------
  FINANCE (26.0%)
    BANKING (15.0%)
     6,700  Chase Manhattan Corp..............................         406
     9,300  First Interstate Bancorp..........................       1,269
    12,100  Wells Fargo & Co..................................       2,614
                                                                ----------
                                                                     4,289
                                                                ----------
    FINANCIAL SERVICES (11.0%)
    31,800  American Express Co...............................       1,316
     6,000  Dean Witter Discover & Co.........................         282
     8,600  Federal National Mortgage Association.............       1,067
     7,000  Student Loan Marketing Association................         461
                                                                ----------
                                                                     3,126
                                                                ----------
  TOTAL FINANCE...............................................       7,415
                                                                ----------
  SERVICES (1.4%)
    TRANSPORTATION (1.4%)
   +26,600  Canadian National Railway.........................         399
                                                                ----------
  TECHNOLOGY (8.5%)
    COMPUTERS (0.8%)
    +3,000  Intuit, Inc.......................................         234
                                                                ----------
    ELECTRONICS (3.7%)
    +9,600  Applied Materials, Inc............................         378
     4,500  Intel Corp........................................         255
     9,300  Watkins-Johnson Co................................         407
                                                                ----------
                                                                     1,040
                                                                ----------
    OFFICE EQUIPMENT (4.0%)
    +5,500  Digital Equipment Corp............................         352
     8,500  International Business Machines Corp..............         780
                                                                ----------
                                                                     1,132
                                                                ----------
  TOTAL TECHNOLOGY............................................       2,406
                                                                ----------
TOTAL COMMON STOCKS (Cost $27,097)............................      28,892
                                                                ----------
</TABLE>
 
<TABLE>
<CAPTION>
   FACE
  AMOUNT
  (000)
- ----------
<C>         <S>                                                 <C>
SHORT-TERM INVESTMENT (5.6%)
  U.S. GOVERNMENT AGENCY OBLIGATION (5.6%)
  $ 1,600   Federal National Mortgage Association Discount
              Note 5.50%, 1/22/96
              (Cost $1,595)...................................       1,595
                                                                ----------
TOTAL INVESTMENTS (106.8%) (Cost $28,692).....................      30,487
                                                                ----------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Aggressive Equity Portfolio
 
                                       62
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE AGGRESSIVE EQUITY PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                  AMOUNT
                                                                  (000)
<S>                                                 <C>         <C>
- ------------------------------------------------------------
OTHER ASSETS (12.0%)
  Receivable for Securities Sold Short............  $    2,707
  Receivable for Investments Sold.................         448
  Receivable for Portfolio Shares Sold............         210
  Dividends Receivable............................          62
  Other...........................................           1  $   3,428
                                                    ----------
LIABILITIES (-18.8%)
  Securities Sold Short, at Value (Proceeds
   $2,707)........................................      (2,642)
  Bank Overdraft..................................      (1,797)
  Payable for Investments Purchased...............        (873)
  Investment Advisory Fees Payable................         (22)
  Administrative Fees Payable.....................          (4)
  Custodian Fees Payable..........................          (3)
  Other Liabilities...............................         (26)    (5,367 )
                                                    ----------  ----------
NET ASSETS (100%).............................................  $  28,548
                                                                ----------
                                                                ----------
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 2,345,287 outstanding $.001 par value shares
  (authorized 500,000,000 shares).............................      $12.17
                                                                ----------
                                                                ----------
</TABLE>
 
- ------------------------------------------------------------
 
<TABLE>
<S>        <C>        <C>
+             --      Non-income producing security
</TABLE>
 
Interest rate disclosed for U.S. Government Agency discount note
represents effective yields at December 31, 1995.
- ------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                          VALUE
 SHARES                                                   (000)
- ------------------------------------------------------------
SECURITIES SOLD SHORT (NOTE A-9)
<C>        <S>                                          <C>
   26,600  Canadian National Railway..................  $     399
    5,500  Digital Equipment Corp.....................        352
    3,000  Intuit, Inc................................        234
   16,200  Pharmacia & Upjohn, Inc....................        628
   12,000  Ralston Purina Group.......................        749
    8,400  UST, Inc...................................        280
                                                        ---------
           (Total Proceeds $2,707)....................  $   2,642
                                                        ---------
                                                        ---------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                     Aggressive Equity Portfolio
 
                                       63
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE EMERGING GROWTH PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
<C>         <S>                                                 <C>
              ------------------------------------------------------------
COMMON STOCKS (97.3%)
  CONSUMER-CYCLICAL (19.4%)
    FOOD SERVICE & LODGING (6.8%)
   +37,700  Cheesecake Factory, Inc...........................  $      801
   +45,000  HFS, Inc..........................................       3,679
    70,000  Promus Hotel Corp.................................       1,558
  +111,600  Sonic Corp........................................       2,064
                                                                ----------
                                                                     8,102
                                                                ----------
    PRINTING & PUBLISHING (3.3%)
    80,000  Lee Enterprises, Inc..............................       1,840
   +27,000  Scholastic Corp...................................       2,099
                                                                ----------
                                                                     3,939
                                                                ----------
    RETAIL-GENERAL (9.3%)
   +70,000  Bed, Bath & Beyond, Inc...........................       2,704
   +35,000  Central Tractor Farm & Country, Inc...............         359
  +120,000  General Nutrition Cos., Inc.......................       2,760
   +30,000  Kohl's Corp.......................................       1,575
   +75,000  OfficeMax, Inc....................................       1,678
   +88,000  Sunglass Hut International, Inc...................       2,068
                                                                ----------
                                                                    11,144
                                                                ----------
  TOTAL CONSUMER-CYCLICAL.....................................      23,185
                                                                ----------
  CONSUMER-STAPLES (29.5%)
    DRUGS (6.1%)
   +60,000  Forest Laboratories, Inc..........................       2,715
    28,000  Genzyme Corp. -- General Division.................       1,736
    +9,800  Immucor, Inc......................................          91
   +55,000  Scherer (R.P.) Corp...............................       2,702
                                                                ----------
                                                                     7,244
                                                                ----------
    HEALTH CARE SUPPLIES & SERVICES (19.5%)
    47,000  Arrow International, Inc..........................       1,868
    55,000  Ballard Medical Products..........................         983
  +120,000  Biomet, Inc.......................................       2,130
   +50,000  Haemonetics Corp..................................         887
   +85,000  Health Management Systems, Inc....................       3,273
  +115,000  Healthsource, Inc.................................       4,140
  +130,000  HEALTHSOUTH Rehabilitation Corp...................       3,786
    +6,400  Mariner Health Group, Inc.........................         107
   +75,000  Research Medical, Inc.............................       2,025
   +40,000  Vencor, Inc.......................................       1,300
  +112,500  Vivra, Inc........................................       2,827
                                                                ----------
                                                                    23,326
                                                                ----------
    HOSPITAL MANAGEMENT (1.5%)
    36,000  American Oncology Resources, Inc..................       1,750
                                                                ----------
    MISCELLANEOUS (2.4%)
   +60,000  IDEXX Laboratories, Inc...........................       2,820
                                                                ----------
  TOTAL CONSUMER-STAPLES......................................      35,140
                                                                ----------
  FINANCE (3.3%)
    INSURANCE (3.3%)
    50,000  Mutual Risk Management Ltd........................       2,288
 
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
<C>         <S>                                                 <C>
              ------------------------------------------------------------
    45,000  NAC Re Corp.......................................  $    1,620
                                                                ----------
  TOTAL FINANCE...............................................       3,908
                                                                ----------
  MATERIALS (2.9%)
    MISCELLANEOUS (2.9%)
   +75,000  Viking Office Products, Inc.......................       3,487
                                                                ----------
  SERVICES (14.7%)
    BUSINESS SERVICES (3.4%)
    60,000  First Data Corp...................................       4,012
     3,000  Sitel Corp........................................          92
                                                                ----------
                                                                     4,104
                                                                ----------
    PROFESSIONAL SERVICES (11.2%)
   +19,900  American Business Information, Inc................         386
   +44,900  American Medical Response, Inc....................       1,459
    75,000  Cintas Corp.......................................       3,338
    60,000  CRA Managed Care, Inc.............................       1,313
  +115,000  CUC International, Inc............................       3,924
   115,000  G & K Services, Inc., Class A.....................       2,932
                                                                ----------
                                                                    13,352
                                                                ----------
    TRANSPORTATION (0.1%)
     4,500  Midwest Express Holdings, Inc.....................         125
                                                                ----------
  TOTAL SERVICES..............................................      17,581
                                                                ----------
  TECHNOLOGY (27.5%)
    ELECTRONICS (13.7%)
   +60,000  Electroglas, Inc..................................       1,470
   +39,900  Fusion Systems Corp...............................       1,117
   +50,100  Level One Communications, Inc.....................         902
    90,000  Linear Technology, Inc............................       3,532
   +70,000  Maxim Integrated Products, Inc....................       2,678
   +35,000  Microchip Technology, Inc.........................       1,278
    70,000  Molex, Inc., Class A..............................       2,144
  +110,000  Xilinx, Inc.......................................       3,327
                                                                ----------
                                                                    16,448
                                                                ----------
    OFFICE EQUIPMENT (12.9%)
     8,600  Adobe Systems, Inc................................         533
   +75,000  BISYS Group, Inc..................................       2,306
   +75,000  Concord EFS Corp..................................       3,094
  +134,850  Informix Corp.....................................       4,045
   +52,600  Progress Software Corp............................       1,946
  +125,000  SunGard Data Systems, Inc.........................       3,469
                                                                ----------
                                                                    15,393
                                                                ----------
    TELECOMMUNICATIONS (0.9%)
   +50,000  Mobile Telecommunications Technologies Corp.......       1,063
                                                                ----------
  TOTAL TECHNOLOGY............................................      32,904
                                                                ----------
TOTAL COMMON STOCKS (Cost $63,267)............................     116,205
                                                                ----------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Emerging Growth Portfolio
 
                                       66
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE EMERGING GROWTH PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
   FACE
  AMOUNT                                                          VALUE
  (000)                                                           (000)
              ------------------------------------------------------------
<C>         <S>                                                 <C>
SHORT-TERM INVESTMENT (2.6%)
  REPURCHASE AGREEMENT (2.6%)
 $   3,053  The Chase Manhattan Bank, N.A., 5.35%, dated
              12/29/95, due 1/02/96, to be repurchased at
              $3,055, collateralized by $2,570 United States
              Treasury Bonds, 7.625%, due 11/15/22, valued at
              $3,113 (Cost $3,053)............................  $    3,053
                                                                ----------
TOTAL INVESTMENTS (99.9%) (Cost $66,320)......................     119,258
                                                                ----------
</TABLE>
 
<TABLE>
<S>                                                 <C>         <C>
OTHER ASSETS (0.5%)
  Cash............................................  $        1
  Receivable for Portfolio Shares Sold............         318
  Receivable for Investments Sold.................         190
  Dividends Receivable............................          27
  Interest Receivable.............................           1
  Other...........................................          10         547
                                                         -----
LIABILITIES (-0.4%)
  Investment Advisory Fees Payable................        (332)
  Payable for Portfolio Shares Redeemed...........         (47)
  Administrative Fees Payable.....................         (16)
  Custodian Fees Payable..........................          (4)
  Other Liabilities...............................         (28)       (427)
                                                         -----  ----------
NET ASSETS (100%).............................................  $  119,378
                                                                ----------
                                                                ----------
</TABLE>
 
<TABLE>
<C>         <S>                                                 <C>
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 5,554,674 outstanding $.001 par value shares
  (authorized 500,000,000 shares).............................      $21.49
                                                                ----------
                                                                ----------
</TABLE>
 
- ------------------------------------------------------------
 
<TABLE>
<S>        <C>        <C>
+             --      Non-income producing security
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                       Emerging Growth Portfolio
 
                                       67
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE EQUITY GROWTH PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
<C>         <S>                                                 <C>
- ------------------------------------------------------------
COMMON STOCKS (94.2%)
  CAPITAL GOODS/CONSTRUCTION (8.5%)
    AEROSPACE & DEFENSE (6.6%)
    17,500  Boeing Co.........................................  $    1,371
    15,100  General Dynamics Corp.............................         893
    +6,500  Litton Industries, Inc............................         289
    10,900  Lockheed Martin Corp..............................         861
    35,500  McDonnell Douglas Corp............................       3,266
    38,700  United Technologies Corp..........................       3,672
                                                                ----------
                                                                    10,352
                                                                ----------
    MACHINERY (1.9%)
    43,000  Sundstrand Corp...................................       3,026
                                                                ----------
  TOTAL CAPITAL GOODS/CONSTRUCTION............................      13,378
                                                                ----------
  CONSUMER-CYCLICAL (19.0%)
    AUTOMOTIVE (1.0%)
    34,300  Goodyear Tire & Rubber Co.........................       1,556
                                                                ----------
    BROADCAST-RADIO & TELEVISION (2.3%)
   +40,000  Infinity Broadcasting, Class A....................       1,490
   +52,400  New World Communications Group, Inc...............         917
   +26,797  Viacom, Inc., Class B.............................       1,269
                                                                ----------
                                                                     3,676
                                                                ----------
    ENTERTAINMENT & LEISURE (1.3%)
   +24,300  AMC Entertainment, Inc............................         568
    26,000  Walt Disney Co....................................       1,534
                                                                ----------
                                                                     2,102
                                                                ----------
    FOOD SERVICE & LODGING (3.0%)
   +28,000  Boston Chicken, Inc...............................         899
   +34,300  HFS, Inc..........................................       2,804
    39,200  La Quinta Inns, Inc...............................       1,073
                                                                ----------
                                                                     4,776
                                                                ----------
    GAMING & LODGING (0.1%)
   +10,100  Trump Hotels & Casino Resort......................         217
                                                                ----------
    HOUSEHOLD FURNISHINGS & APPLIANCES (2.0%)
   +78,700  American Standard Co..............................       2,203
    59,700  AMRE, Inc.........................................         873
                                                                ----------
                                                                     3,076
                                                                ----------
    LEISURE RELATED (1.3%)
    22,400  Eastman Kodak Co..................................       1,501
   +23,500  Toy Biz, Inc......................................         511
                                                                ----------
                                                                     2,012
                                                                ----------
    PUBLISHING (3.1%)
    29,800  Gannett Co., Inc..................................       1,829
  +175,900  K-III Communications, Corp........................       2,133
    31,300  New York Times Co., Class A.......................         927
                                                                ----------
                                                                     4,889
                                                                ----------
 
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
<C>         <S>                                                 <C>
- ------------------------------------------------------------
    RETAIL-GENERAL (4.9%)
   +60,700  AutoZone, Inc.....................................  $    1,753
   +84,200  General Nutrition Cos., Inc.......................       1,937
    32,000  Harcourt General, Inc.............................       1,340
    31,300  Home Depot, Inc...................................       1,498
   +17,600  PetSmart, Inc.....................................         546
    14,100  Tandy Corp........................................         585
                                                                ----------
                                                                     7,659
                                                                ----------
  TOTAL CONSUMER-CYCLICAL.....................................      29,963
                                                                ----------
  CONSUMER-STAPLES (20.9%)
    APPAREL & TEXTILES (0.5%)
     7,400  NIKE, Inc., Class B...............................         515
    11,200  Reebok International Ltd..........................         316
                                                                ----------
                                                                       831
                                                                ----------
    BEVERAGES & TOBACCO (11.7%)
    68,600  Coca Cola Enterprises, Inc........................       1,835
   161,500  Philip Morris Cos., Inc...........................      14,616
    66,600  RJR Nabisco Holdings Corp.........................       2,056
                                                                ----------
                                                                    18,507
                                                                ----------
    DRUGS (3.3%)
    15,500  American Home Products Corp.......................       1,504
    28,900  Pfizer, Inc.......................................       1,821
    35,700  Schering-Plough Corp..............................       1,955
                                                                ----------
                                                                     5,280
                                                                ----------
    FOOD (2.2%)
    23,800  Interstate Bakeries Corp..........................         532
    12,600  Kellogg Co........................................         973
     9,100  Ralston Purina Group..............................         568
    25,400  Wrigley (William) Jr. Co..........................       1,334
                                                                ----------
                                                                     3,407
                                                                ----------
    HEALTH CARE SUPPLIES & SERVICES (3.2%)
    17,800  Aetna Life & Casualty Co..........................       1,232
    33,000  Columbia/HCA Healthcare Corp......................       1,675
    13,600  United Healthcare Corp............................         891
    26,700  US Healthcare, Inc................................       1,242
                                                                ----------
                                                                     5,040
                                                                ----------
  TOTAL CONSUMER-STAPLES......................................      33,065
                                                                ----------
  DIVERSIFIED (3.4%)
    48,900  Loews Corp........................................       3,833
    23,400  Textron, Inc......................................       1,580
                                                                ----------
  TOTAL DIVERSIFIED...........................................       5,413
                                                                ----------
  FINANCE (23.1%)
    BANKING (10.1%)
    22,100  Chase Manhattan Corp..............................       1,340
    32,000  Citicorp..........................................       2,152
    28,300  First Interstate Bancorp..........................       3,863
    23,800  Morgan (J.P.) & Co., Inc..........................       1,910
    31,200  Wells Fargo & Co..................................       6,739
                                                                ----------
                                                                    16,004
                                                                ----------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Equity Growth Portfolio
 
                                       70
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE EQUITY GROWTH PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
    FINANCIAL SERVICES (10.6%)
   110,600  American Express Co...............................  $    4,576
    12,400  CIGNA Corp........................................       1,280
    40,000  Dean Witter Discover & Co.........................       1,880
    22,800  Federal Home Loan Mortgage Corp...................       1,904
    19,400  Federal National Mortgage Association.............       2,408
    26,000  Franklin Resources, Inc...........................       1,310
    29,900  Household International, Inc......................       1,768
    24,000  Student Loan Marketing Association................       1,581
                                                                ----------
                                                                    16,707
                                                                ----------
    INSURANCE (2.4%)
    31,300  Ace Ltd...........................................       1,244
    38,900  Exel Ltd..........................................       2,373
    +9,500  GCR Holdings, Ltd.................................         211
                                                                ----------
                                                                     3,828
                                                                ----------
  TOTAL FINANCE...............................................      36,539
                                                                ----------
  MATERIALS (2.9%)
    CHEMICALS (2.9%)
    26,400  Hercules, Inc.....................................       1,488
    18,800  IMC Global, Inc...................................         769
     9,100  Monsanto Co.......................................       1,115
    15,600  Olin Corp.........................................       1,158
                                                                ----------
  TOTAL MATERIALS.............................................       4,530
                                                                ----------
  SERVICES (3.0%)
    BUSINESS SERVICES (1.0%)
    22,600  First Data Corp...................................       1,511
                                                                ----------
    PROFESSIONAL SERVICES (1.1%)
   +15,200  Bell & Howell Holding Co..........................         426
   +38,750  CUC International, Inc............................       1,322
                                                                ----------
                                                                     1,748
                                                                ----------
    TRANSPORTATION (0.9%)
   +10,800  AMR Corp..........................................         802
   +51,300  USAir Group, Inc..................................         680
                                                                ----------
                                                                     1,482
                                                                ----------
  TOTAL SERVICES..............................................       4,741
                                                                ----------
  TECHNOLOGY (13.4%)
    COMPUTERS (3.8%)
   +12,800  Cisco Systems, Inc................................         955
    18,900  Hewlett Packard Co................................       1,583
    26,700  International Business Machines Corp..............       2,450
   +23,200  Seagate Technology, Inc...........................       1,102
                                                                ----------
                                                                     6,090
                                                                ----------
    ELECTRONICS (4.6%)
   +40,600  Applied Materials, Inc............................       1,599
    19,800  Intel Corp........................................       1,124
   +28,100  LSI Logic Corp....................................         920
    19,300  Motorola, Inc.....................................       1,100
    15,400  Texas Instruments, Inc............................         797
    40,900  Watkins-Johnson Co................................       1,789
                                                                ----------
                                                                     7,329
                                                                ----------
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
<C>         <S>                                                 <C>
- ------------------------------------------------------------
    OFFICE EQUIPMENT (0.6%)
    26,100  Reynolds & Reynolds, Class A......................  $    1,015
                                                                ----------
    SOFTWARE SERVICES (2.0%)
   +18,900  Microsoft Corp....................................       1,658
   +33,900  Oracle System Corp................................       1,437
                                                                ----------
                                                                     3,095
                                                                ----------
    TELECOMMUNICATIONS (2.4%)
   +26,400  AirTouch Communications, Inc......................         746
    23,700  American Telephone & Telegraph Corp...............       1,535
    56,400  MCI Communications Corp...........................       1,473
                                                                ----------
                                                                     3,754
                                                                ----------
  TOTAL TECHNOLOGY............................................      21,283
                                                                ----------
TOTAL COMMON STOCKS (Cost $132,472)...........................     148,912
                                                                ----------
<CAPTION>
   FACE
  AMOUNT
  (000)
- ----------
<C>         <S>                                                 <C>
SHORT-TERM INVESTMENT (6.2%)
  REPURCHASE AGREEMENT (6.2%)
$    9,800  Goldman Sachs & Co., 5.83%, dated 12/29/95, due
              1/02/96, to be repurchased at $9,806,
              collateralized by $6,105 United States Treasury
              Bonds, 13.875%, due 5/15/11, valued at $10,006
              (Cost $9,800)...................................       9,800
                                                                ----------
TOTAL INVESTMENTS (100.4%) (Cost $142,272)....................     158,712
                                                                ----------
</TABLE>
 
<TABLE>
<S>                                                 <C>         <C>
OTHER ASSETS (2.3%)
  Receivable for Investments Sold.................  $    3,215
  Dividends Receivable............................         353
  Receivable for Portfolio Shares Sold............          65
  Interest Receivable.............................           5
  Other...........................................           9       3,647
                                                    ----------
LIABILITIES (-2.7%)
  Payable for Investments Purchased...............      (2,782)
  Payable for Portfolio Shares Redeemed...........      (1,176)
  Investment Advisory Fees Payable................        (224)
  Administrative Fees Payable.....................         (22)
  Custodian Fees Payable..........................          (7)
  Other Liabilities...............................         (36)     (4,247)
                                                    ----------  ----------
NET ASSETS (100%).............................................  $  158,112
                                                                ----------
                                                                ----------
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 11,182,044 outstanding $.001 par value shares
  (authorized 500,000,000 shares).............................      $14.14
                                                                ----------
                                                                ----------
</TABLE>
 
- ------------------------------------------------------------
+ -- Non-income producing security
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                         Equity Growth Portfolio
 
                                       71
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE SMALL CAP VALUE EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
COMMON STOCKS (95.7%)
  AEROSPACE (2.2%)
    27,000  AAR Corp..........................................  $      594
    16,000  Thiokol Corp......................................         542
       300  United Industrial Corp............................           2
                                                                ----------
                                                                     1,138
                                                                ----------
  BANKING (9.5%)
    17,450  First Security Corp. (Delaware)...................         672
    24,000  Greenpoint Financial Corp.........................         642
    15,600  Onbancorp, Inc....................................         521
    25,000  Peoples Heritage Financial Group, Inc.............         569
    16,000  Standard Federal Bank.............................         630
    29,000  Trustmark Corp....................................         660
    20,000  Union Planters Corp...............................         638
    21,000  Washington Mutual, Inc............................         606
                                                                ----------
                                                                     4,938
                                                                ----------
  BUILDING (1.9%)
    13,300  Ameron, Inc. (Delaware)...........................         500
    38,800  Gilbert Associates, Inc., Class A.................         485
                                                                ----------
                                                                       985
                                                                ----------
  CAPITAL GOODS (4.2%)
    21,403  Binks Manufacturing Co............................         503
    33,200  Cascade Corp......................................         465
    21,600  Starrett (L.S.) Co., Class A......................         559
    12,200  Tecumseh Products Co., Class A....................         631
                                                                ----------
                                                                     2,158
                                                                ----------
  CHEMICALS (4.8%)
    33,792  Aceto Corp........................................         541
    23,400  Dexter Corp.......................................         553
    19,400  Learonal, Inc.....................................         446
    29,800  Quaker Chemical Corp..............................         402
    18,000  Witco Corp........................................         527
                                                                ----------
                                                                     2,469
                                                                ----------
  COMMUNICATIONS (1.1%)
    30,200  Comsat Corp.......................................         562
                                                                ----------
  CONSUMER-DURABLES (3.9%)
    26,200  Arvin Industries, Inc.............................         432
    30,298  Knape & Vogt Manufacturing Co.....................         526
    31,300  Oneida Ltd........................................         552
    25,100  Smith (A.O.) Corp., Class B.......................         521
                                                                ----------
                                                                     2,031
                                                                ----------
  CONSUMER-RETAIL (4.1%)
    31,800  CPI Corp..........................................         509
    25,500  Deb Shops, Inc....................................          88
    25,700  Guilford Mills, Inc...............................         523
    23,000  Ross Stores, Inc.                                          440
    14,100  Springs Industries, Inc., Class A.................         583
                                                                ----------
                                                                     2,143
                                                                ----------
 
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
  CONSUMER-STAPLES (4.3%)
    15,246  Block Drug Co., Inc., Class A.....................  $      530
    30,400  Coors (Adolph), Inc., Class B.....................         673
    27,900  International Multifoods Corp.....................         561
    26,400  Nash Finch Co.....................................         482
                                                                ----------
                                                                     2,246
                                                                ----------
  ENERGY (3.3%)
    24,600  Ashland Coal, Inc.................................         526
    21,000  Diamond Shamrock, Inc.............................         543
    25,500  Ultramar Corp.....................................         657
                                                                ----------
                                                                     1,726
                                                                ----------
  FINANCIAL-DIVERSIFIED (4.6%)
    11,900  Finova Group, Inc.................................         574
    10,100  GATX Corp.........................................         491
    35,000  Manufactured Home Communities, Inc. REIT..........         613
    28,000  South West Property Trust REIT....................         378
    14,000  Wellsford Residential Property Trust REIT.........         322
                                                                ----------
                                                                     2,378
                                                                ----------
  HEALTH CARE (6.7%)
    30,000  Analogic Corp.....................................         555
    14,500  Beckman Instruments, Inc..........................         513
    26,400  Bergen Brunswig Corp., Class A....................         657
    35,500  Bindley Western Industries........................         604
    49,700  Kinetic Concepts, Inc.............................         596
    26,000  United Wisconsin Services, Inc....................         572
                                                                ----------
                                                                     3,497
                                                                ----------
  INDUSTRIAL (5.8%)
    17,200  American Filtrona Corp............................         576
    13,400  Barnes Group, Inc.................................         482
    50,700  GenCorp, Inc......................................         621
    44,500  Kaman Corp., Class A..............................         495
    34,900  Zero Corp. (Delaware).............................         620
    10,300  Zurn Industries, Inc..............................         220
                                                                ----------
                                                                     3,014
                                                                ----------
  INSURANCE (5.8%)
    16,200  Argonaut Group, Inc...............................         526
    25,000  Enhance Financial Services Group, Inc.............         666
    19,500  Provident Companies, Inc..........................         661
    15,900  Selective Insurance Group, Inc....................         564
    19,950  USLife Corp.......................................         596
                                                                ----------
                                                                     3,013
                                                                ----------
  METALS (2.1%)
    35,700  Birmingham Steel Corp.............................         531
    14,100  Cleveland-Cliffs Iron Co..........................         578
                                                                ----------
                                                                     1,109
                                                                ----------
  PAPER & PACKAGING (2.8%)
    21,500  Ball Corp.........................................         591
    13,900  Potlatch Corp.....................................         556
    25,500  Sealright Co., Inc................................         284
                                                                ----------
                                                                     1,431
                                                                ----------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                Small Cap Value Equity Portfolio
 
                                       75
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE SMALL CAP VALUE EQUITY PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
  SERVICES (11.0%)
    23,200  ABM Industries, Inc...............................  $      644
    21,200  Angelica Corp.....................................         435
    27,000  Bowne & Co........................................         540
    30,700  Cross (A.T.) Co., Class A.........................         464
    38,000  Jackpot Enterprises, Inc..........................         442
    18,400  National Service Industries, Inc..................         596
    20,900  New England Business Services, Inc................         455
    24,400  Ogden Corp........................................         521
    55,400  Piccadilly Cafeterias, Inc........................         526
    41,500  Russ Berrie & Co., Inc............................         524
    25,000  Sbarro, Inc.......................................         537
                                                                ----------
                                                                     5,684
                                                                ----------
  TECHNOLOGY (7.7%)
    36,000  Augat, Inc........................................         616
    48,000  Core Industries, Inc..............................         618
    21,800  Cubic Corp........................................         621
    33,700  Gerber Scientific, Inc............................         548
    15,900  MTS Systems Corp..................................         525
    30,500  National Computer Systems, Inc....................         576
    36,000  Scitex Ltd........................................         490
                                                                ----------
                                                                     3,994
                                                                ----------
  TRANSPORTATION (2.5%)
    22,000  Airborne Freight Corp.............................         586
    19,800  Overseas Shipholding Group, Inc...................         376
    28,000  SkyWest, Inc......................................         360
                                                                ----------
                                                                     1,322
                                                                ----------
  UTILITIES (7.4%)
    19,700  Central Hudson Gas & Electric.....................         608
    13,300  Commonwealth Energy Systems Cos...................         595
    15,000  Eastern Enterprises...............................         529
    25,900  Oneok, Inc........................................         592
    13,700  Orange & Rockland Utilities, Inc..................         490
    13,700  SJW Corp..........................................         517
    28,500  Washington Water Power Co.........................         499
                                                                ----------
                                                                     3,830
                                                                ----------
TOTAL COMMON STOCKS (Cost $44,714)............................      49,668
                                                                ----------
</TABLE>
 
<TABLE>
<CAPTION>
   FACE
  AMOUNT                                                          VALUE
  (000)                                                           (000)
<C>         <S>                                                 <C>
- ------------------------------------------------------------
SHORT-TERM INVESTMENT (4.1%)
  REPURCHASE AGREEMENT (4.1%)
$   2,127   The Chase Manhattan Bank, N.A., 5.35%, dated
              12/29/95, due 1/02/96, to be repurchased at
              $2,128, collateralized by $1,800 United States
              Treasury Bonds, 7.50%, due 11/15/24, valued at
              $2,171 (Cost $2,127)............................  $    2,127
                                                                ----------
TOTAL INVESTMENTS (99.8%) (Cost $46,841)......................      51,795
                                                                ----------
</TABLE>
 
<TABLE>
<S>                                                 <C>         <C>
OTHER ASSETS (0.5%)
  Dividends Receivable............................  $      126
  Receivable for Investments Sold.................         121
  Interest Receivable.............................           1
  Other...........................................           4         252
                                                    ----------
LIABILITIES (-0.3%)
  Investment Advisory Fees Payable................         (91)
  Administrative Fees Payable.....................          (7)
  Custodian Fees Payable..........................          (3)
  Payable for Portfolio Shares Redeemed...........          (1)
  Other Liabilities...............................         (26)       (128)
                                                    ----------  ----------
NET ASSETS (100%).............................................  $   51,919
                                                                ----------
                                                                ----------
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 4,357,807 outstanding $.001 par value shares
  (authorized 500,000,000 shares).............................      $11.91
                                                                ----------
                                                                ----------
</TABLE>
 
- ------------------------------------------------------------
REIT -- Real Estate Investment Trust
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Small Cap Value Equity Portfolio
 
                                       76
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE U.S. REAL ESTATE PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
COMMON STOCKS (96.0%)
  APARTMENT (18.6%)
    47,300  Associated Estates Realty Corp. REIT..............  $    1,017
   123,800  Avalon Properties, Inc. REIT......................       2,662
    31,100  Camden Property Trust REIT........................         742
   125,900  Essex Property Trust, Inc. REIT...................       2,424
    61,100  Evans Withycombe Residential, Inc. REIT...........       1,314
    50,300  Paragon Group, Inc. REIT..........................         874
     9,700  South West Property Trust REIT....................         131
   135,000  Walden Residential Properties, Inc. REIT..........       2,818
    40,700  Wellsford Residential Property Trust REIT.........         936
                                                                ----------
                                                                    12,918
                                                                ----------
  LAND (2.5%)
  +196,200  Atlantic Gulf Communities Corp....................       1,324
   +69,800  Catellus Development Corp.........................         419
                                                                ----------
                                                                     1,743
                                                                ----------
  LODGING/LEISURE (17.8%)
    40,000  Felcor Suite Hotels, Inc. REIT....................       1,110
  +220,500  Host Marriot Corp.................................       2,922
  +207,500  John Q Hammons Hotels, Inc........................       1,919
  +246,600  Prime Hospitality Corp............................       2,466
    54,200  Red Lion Hotels, Inc..............................         949
  +117,600  Servico, Inc......................................       1,235
  +187,400  ShoLodge, Inc.....................................       1,780
                                                                ----------
                                                                    12,381
                                                                ----------
  MANUFACTURED HOME (6.1%)
    90,800  Manufactured Home Communities, Inc. REIT..........       1,589
   109,650  ROC Communities, Inc. REIT........................       2,632
                                                                ----------
                                                                     4,221
                                                                ----------
  OFFICE AND INDUSTRIAL (25.9%)
    INDUSTRIAL (1.7%)
    53,700  First Industrial Realty Trust, Inc. REIT..........       1,208
                                                                ----------
    OFFICE (7.4%)
   101,500  Beacon Properties Corp. REIT......................       2,335
    67,500  Carr Realty Corp. REIT............................       1,645
     6,900  Crescent Real Estate Equities, Inc. REIT..........         235
   106,100  Crocker Realty Trust, Inc. REIT...................         942
                                                                ----------
                                                                     5,157
                                                                ----------
    OFFICE AND INDUSTRIAL (16.8%)
   257,400  Bedford Property Investors, Inc. REIT.............       1,866
    54,600  Duke Realty Investments, Inc. REIT................       1,713
    49,100  Highwoods Properties, Inc. REIT...................       1,387
   160,700  Liberty Property Trust REIT.......................       3,335
    60,600  Reckson Associates Realty Corp. REIT..............       1,780
    64,000  Spieker Properties, Inc. REIT.....................       1,608
                                                                ----------
                                                                    11,689
                                                                ----------
  TOTAL OFFICE AND INDUSTRIAL.................................      18,054
                                                                ----------
  SELF STORAGE (4.7%)
   173,000  Public Storage, Inc. REIT.........................       3,287
                                                                ----------
 
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
 
  SHOPPING CENTER (20.4%)
    FACTORY OUTLET CENTER (1.9%)
    58,100  HGI Realty, Inc. REIT.............................  $    1,329
                                                                ----------
    REGIONAL MALL (14.3%)
   343,100  Crown American Realty Trust REIT..................       2,702
   235,000  DeBartolo Realty Corp. REIT.......................       3,055
   222,900  Glimcher Realty Trust REIT........................       3,845
    13,600  Rouse Co..........................................         277
     3,700  Taubman Centers, Inc. REIT........................          37
                                                                ----------
                                                                     9,916
                                                                ----------
  SHOPPING CENTER (4.2%)
   185,500  Alexander Haagen Properties, Inc. REIT............       2,272
    55,700  Burnham Pacific Property Trust REIT...............         536
     6,800  Kranzco Realty Trust REIT.........................         100
                                                                ----------
                                                                     2,908
                                                                ----------
  TOTAL SHOPPING CENTER.......................................      14,153
                                                                ----------
TOTAL COMMON STOCKS (Cost $62,861)............................      66,757
                                                                ----------
</TABLE>
 
<TABLE>
<CAPTION>
   FACE
  AMOUNT
  (000)
- ----------
<C>         <S>                                                 <C>
SHORT-TERM INVESTMENT (3.3%)
  REPURCHASE AGREEMENT (3.3%)
$   2,315   The Chase Manhattan Bank, N.A., 5.35%, dated
              12/29/95, due 1/02/96, to be repurchased at
              $2,316, collateralized by $1,510 United States
              Treasury Bonds, 10.625%, due 8/15/15, valued at
              $2,363 (Cost $2,315)............................       2,315
                                                                ----------
TOTAL INVESTMENTS (99.3%) (Cost $65,176)......................      69,072
                                                                ----------
</TABLE>
 
<TABLE>
<S>                                                 <C>         <C>
OTHER ASSETS (4.7%)
  Cash............................................  $        1
  Receivable for Investments Sold.................       2,649
  Dividends Receivable............................         588
  Receivable for Portfolio Shares Sold............          35
  Interest Receivable.............................           1
  Other...........................................           2       3,276
                                                    ----------
LIABILITIES (-4.0%)
  Payable for Investments Purchased...............      (2,706)
  Investment Advisory Fees Payable................         (78)
  Administrative Fees Payable.....................          (9)
  Custodian Fees Payable..........................          (6)
  Payable for Portfolio Shares Redeemed...........          (3)
  Other Liabilities...............................         (37)     (2,839)
                                                    ----------  ----------
NET ASSETS (100%).............................................  $   69,509
                                                                ----------
                                                                ----------
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 6,086,542 outstanding $.001 par value shares
  (authorized 500,000,000 shares).............................      $11.42
                                                                ----------
                                                                ----------
</TABLE>
 
- ------------------------------------------------------------
+    -- Non-income producing security
REIT -- Real Estate Investment Trust
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
U.S. Real Estate Portfolio
 
                                       80
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE VALUE EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
<C>         <S>                                                 <C>
- ------------------------------------------------------------
COMMON STOCKS (98.1%)
  AEROSPACE (2.1%)
    33,300  United Technologies Corp..........................  $    3,159
                                                                ----------
  BANKING (12.5%)
    43,750  BankAmerica Corp..................................       2,833
    44,000  Bankers Trust (New York) Corp.....................       2,926
    53,700  Chemical Banking Corp.............................       3,155
    74,000  First of America Bank Corp........................       3,283
    58,550  Mellon Bank Corp..................................       3,147
    95,000  PNC Bank Corp.....................................       3,064
                                                                ----------
                                                                    18,408
                                                                ----------
  CAPITAL GOODS (2.1%)
    86,700  Deere & Co........................................       3,056
                                                                ----------
  CHEMICALS (4.0%)
    41,275  Eastman Chemical Co...............................       2,585
    27,100  Monsanto Co.......................................       3,320
                                                                ----------
                                                                     5,905
                                                                ----------
  COMMUNICATIONS (6.6%)
    60,200  NYNEX Corp........................................       3,251
    54,800  SBC Communications, Inc...........................       3,151
    84,100  Sprint Corp.......................................       3,353
                                                                ----------
                                                                     9,755
                                                                ----------
  CONSUMER-DURABLES (4.9%)
    35,000  Chrysler Corp.....................................       1,938
    86,800  Ford Motor Co.....................................       2,517
    50,900  General Motors Corp...............................       2,692
                                                                ----------
                                                                     7,147
                                                                ----------
  CONSUMER-RETAIL (6.8%)
    61,800  J.C. Penney Co., Inc..............................       2,943
   194,700  Kmart Corp........................................       1,411
   167,800  TJX Companies, Inc................................       3,167
   189,500  Woolworth Corp....................................       2,464
                                                                ----------
                                                                     9,985
                                                                ----------
  CONSUMER-SERVICE & GROWTH (3.5%)
    32,600  Eastman Kodak Co..................................       2,184
   138,900  Ogden Corp........................................       2,969
                                                                ----------
                                                                     5,153
                                                                ----------
  CONSUMER-STAPLES (5.4%)
    68,100  American Brands, Inc..............................       3,039
   154,900  Fleming Cos., Inc.................................       3,195
    51,500  Heinz (H.J.) Co...................................       1,706
                                                                ----------
                                                                     7,940
                                                                ----------
  ENERGY (9.3%)
    86,500  Ashland, Inc......................................       3,038
    33,000  Atlantic Richfield, Co............................       3,655
    21,600  Exxon Corp........................................       1,731
    16,050  Royal Dutch Petroleum Co..........................       2,265
    38,350  Texaco, Inc.......................................       3,011
                                                                ----------
                                                                    13,700
                                                                ----------
 
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
<C>         <S>                                                 <C>
- ------------------------------------------------------------
  FINANCIAL-DIVERSIFIED (1.9%)
    43,250  Student Loan Marketing Association................  $    2,849
                                                                ----------
  HEALTH CARE (3.9%)
    81,900  Bausch & Lomb, Inc................................       3,245
    59,800  Baxter International, Inc.........................       2,504
                                                                ----------
                                                                     5,749
                                                                ----------
  INDUSTRIAL (3.6%)
   147,300  Hanson plc ADR....................................       2,246
    57,100  Rockwell International Corp.......................       3,019
                                                                ----------
                                                                     5,265
                                                                ----------
  INSURANCE (6.6%)
    90,900  American General Corp.............................       3,170
    70,000  Lincoln National Corp.............................       3,763
    51,000  St. Paul Cos., Inc................................       2,837
                                                                ----------
                                                                     9,770
                                                                ----------
  METALS (2.0%)
    48,400  Phelps Dodge Corp.................................       3,013
                                                                ----------
  PAPER & PACKAGING (5.9%)
   121,600  Louisiana-Pacific Corp............................       2,949
    66,000  Weyerhauser Co....................................       2,855
    50,400  Willamette Industries, Inc........................       2,835
                                                                ----------
                                                                     8,639
                                                                ----------
  TECHNOLOGY (3.4%)
    68,000  Apple Computer, Inc...............................       2,168
    51,200  Harris Corp.......................................       2,796
                                                                ----------
                                                                     4,964
                                                                ----------
  TRANSPORTATION (3.7%)
   +32,000  AMR Corp..........................................       2,376
   128,000  Ryder System, Inc.................................       3,168
                                                                ----------
                                                                     5,544
                                                                ----------
  UTILITIES (9.9%)
   106,700  General Public Utilities Corp.....................       3,628
    92,500  NIPSCO Industries, Inc............................       3,538
   137,400  Pinnacle West Capital Corp........................       3,950
    85,800  Texas Utilities Co................................       3,529
                                                                ----------
                                                                    14,645
                                                                ----------
TOTAL COMMON STOCKS (Cost $129,825)...........................     144,646
                                                                ----------
</TABLE>
 
<TABLE>
<CAPTION>
   FACE
  AMOUNT
  (000)
- ----------
<C>         <S>                                                 <C>
SHORT-TERM INVESTMENT (1.6%)
  REPURCHASE AGREEMENT (1.6%)
$   2,342   The Chase Manhattan Bank, N.A., 5.35%, dated
              12/29/95, due 1/02/96, to be repurchased at
              $2,343, collateralized by $1,905 United States
              Treasury Bonds, 7.875%, due 2/15/21, valued at
              $2,391 (Cost $2,342)............................       2,342
                                                                ----------
TOTAL INVESTMENTS (99.7%) (Cost $132,167).....................     146,988
                                                                ----------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                          Value Equity Portfolio
 
                                       83
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE VALUE EQUITY PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                  AMOUNT
                                                                  (000)
<S>                                                 <C>         <C>
- ------------------------------------------------------------
OTHER ASSETS (0.5%)
  Receivable for Investments Sold.................  $      326
  Dividends Receivable............................         324
  Interest Receivable.............................           1
  Other...........................................           8  $      659
                                                    ----------
LIABILITIES (-0.2%)
  Investment Advisory Fees Payable................        (168)
  Payable for Portfolio Shares Redeemed...........         (50)
  Administrative Fees Payable.....................         (20)
  Custodian Fees Payable..........................          (5)
  Other Liabilities...............................         (39)       (282)
                                                    ----------  ----------
NET ASSETS (100%).............................................  $  147,365
                                                                ----------
                                                                ----------
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 10,568,118 outstanding $.001 par value shares
  (authorized 500,000,000 shares).............................      $13.94
                                                                ----------
                                                                ----------
</TABLE>
 
- ------------------------------------------------------------
+   -- Non-income producing security
ADR -- American Depositary Receipt
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Value Equity Portfolio
 
                                       84
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE BALANCED PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
COMMON STOCKS (50.2%)
  AEROSPACE (1.0%)
     2,300  United Technologies Corp..........................  $      218
                                                                ----------
  BANKING (6.5%)
     3,700  BankAmerica Corp..................................         240
     3,400  Bankers Trust (New York) Corp.....................         226
     4,300  Chemical Banking Corp.............................         252
     6,100  First of America Bank Corp........................         271
     4,700  Mellon Bank Corp..................................         252
     7,400  PNC Bank Corp.....................................         239
                                                                ----------
                                                                     1,480
                                                                ----------
  CAPITAL GOODS (1.1%)
     6,900  Deere & Co........................................         243
                                                                ----------
  CHEMICALS (2.1%)
     3,425  Eastman Chemical Co...............................         214
     2,100  Monsanto Co.......................................         258
                                                                ----------
                                                                       472
                                                                ----------
  COMMUNICATIONS (3.8%)
     5,500  NYNEX Corp........................................         297
     5,000  SBC Communications, Inc...........................         288
     7,200  Sprint Corp.......................................         287
                                                                ----------
                                                                       872
                                                                ----------
  CONSUMER-DURABLES (2.4%)
     2,100  Chrysler Corp.....................................         116
     7,300  Ford Motor Co.....................................         212
     4,300  General Motors Corp...............................         227
                                                                ----------
                                                                       555
                                                                ----------
  CONSUMER-RETAIL (3.6%)
     4,800  J.C. Penney Co., Inc..............................         229
    17,100  Kmart Corp........................................         124
    14,100  TJX Companies, Inc................................         266
    15,300  Woolworth Corp....................................         199
                                                                ----------
                                                                       818
                                                                ----------
  CONSUMER-SERVICE & GROWTH (1.6%)
     2,400  Eastman Kodak Co..................................         161
     9,600  Ogden Corp........................................         205
                                                                ----------
                                                                       366
                                                                ----------
  CONSUMER-STAPLES (3.1%)
     5,500  American Brands, Inc..............................         245
    13,700  Fleming Cos., Inc.................................         283
     5,100  Heinz (H.J.) Co...................................         169
                                                                ----------
                                                                       697
                                                                ----------
 
<CAPTION>
                                                                  VALUE
  SHARES                                                          (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
  ENERGY (4.5%)
     6,600  Ashland, Inc......................................  $      232
     2,500  Atlantic Richfield Co.............................         277
     1,400  Exxon Corp........................................         112
     1,250  Royal Dutch Petroleum Co..........................         176
     3,000  Texaco, Inc.......................................         236
                                                                ----------
                                                                     1,033
                                                                ----------
  FINANCIAL-DIVERSIFIED (0.9%)
     3,000  Student Loan Marketing Association................         198
                                                                ----------
  HEALTH CARE (2.0%)
     6,500  Bausch & Lomb, Inc................................         258
     4,600  Baxter International, Inc.........................         192
                                                                ----------
                                                                       450
                                                                ----------
  INDUSTRIAL (1.9%)
    12,400  Hanson plc ADR....................................         189
     4,400  Rockwell International Corp.......................         233
                                                                ----------
                                                                       422
                                                                ----------
  INSURANCE (3.0%)
     5,900  American General Corp.............................         206
     4,700  Lincoln National Corp.............................         252
     3,800  St. Paul Cos., Inc................................         211
                                                                ----------
                                                                       669
                                                                ----------
  METALS (0.9%)
     3,100  Phelps Dodge Corp.................................         193
                                                                ----------
  PAPER & PACKAGING (3.0%)
     9,500  Louisiana-Pacific Corp............................         230
     5,000  Weyerhauser Co....................................         216
     4,100  Willamette Industries, Inc........................         231
                                                                ----------
                                                                       677
                                                                ----------
  TECHNOLOGY (1.8%)
     5,500  Apple Computer, Inc...............................         175
     4,200  Harris Corp.......................................         230
                                                                ----------
                                                                       405
                                                                ----------
  TRANSPORTATION (1.7%)
    +2,200  AMR Corp..........................................         163
     9,200  Ryder System, Inc.................................         228
                                                                ----------
                                                                       391
                                                                ----------
  UTILITIES (5.3%)
     9,100  General Public Utilities Corp.....................         309
     7,500  NIPSCO Industries, Inc............................         287
    11,100  Pinnacle West Capital Corp........................         319
     7,050  Texas Utilities Co................................         290
                                                                ----------
                                                                     1,205
                                                                ----------
TOTAL COMMON STOCKS (Cost $9,704).............................      11,364
                                                                ----------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                              Balanced Portfolio
 
                                       87
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE BALANCED PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
   FACE
  AMOUNT                                                          VALUE
  (000)                                                           (000)
<C>         <S>                                                 <C>
- ------------------------------------------------------------
FIXED INCOME SECURITIES (44.5%)
  U.S. TREASURY NOTES (44.5%)
$   4,875   8.25%, 7/15/98....................................  $    5,218
    4,803   5.50%, 4/15/00....................................       4,843
                                                                ----------
TOTAL FIXED INCOME SECURITIES (Cost $9,804)...................      10,061
                                                                ----------
SHORT-TERM INVESTMENT (4.4%)
  REPURCHASE AGREEMENT (4.4%)
    1,006   The Chase Manhattan Bank, N.A., 5.35%, dated
              12/29/95, due 1/02/96, to be repurchased at
              $1,007, collateralized by $765 United States
              Treasury Bonds, 10.75%, due 2/15/03, valued at
              $1,025 (Cost $1,006)............................       1,006
                                                                ----------
TOTAL INVESTMENTS (99.1%) (Cost $20,514)......................      22,431
                                                                ----------
</TABLE>
 
<TABLE>
<S>                                                 <C>         <C>
OTHER ASSETS (1.2%)
  Interest Receivable.............................  $      243
  Dividends Receivable............................          24
  Other...........................................           1         268
                                                         -----
LIABILITIES (-0.3%)
  Investment Advisory Fees Payable................         (15)
  Payable for Portfolio Shares Redeemed...........         (13)
  Administrative Fees Payable.....................          (4)
  Custodian Fees Payable..........................          (2)
  Other Liabilities...............................         (23)        (57)
                                                         -----  ----------
NET ASSETS (100%).............................................  $   22,642
                                                                ----------
                                                                ----------
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 2,268,132 outstanding $.001 par value shares
  (authorized 500,000,000 shares).............................       $9.98
                                                                ----------
                                                                ----------
</TABLE>
 
- ------------------------------------------------------------
+   -- Non-income producing security
ADR -- American Depositary Receipt
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Balanced Portfolio
 
                                       88
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE EMERGING MARKETS DEBT PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
     FACE
    AMOUNT                                                               VALUE
    (000)                                                                (000)
<C>              <S>                                                 <C>
- ------------------------------------------------------------
DEBT INSTRUMENTS (90.6%)
  ALGERIA (3.4%)
    LOAN AGREEMENTS (3.4%)
$    p###9,788   Algeria Refinanced Loan Agreements, Tranche A,
                   (Floating Rate), 6.875%, 12/31/00...............  $        5,090
    ~p###2,000   Algeria Refinanced Loan Agreements, Tranche A,
                   (Floating Rate), 12/31/00 (Participation:
                   Salomon Brothers)...............................           1,040
                                                                     --------------
                                                                              6,130
                                                                     --------------
  ARGENTINA (25.9%)
    BONDS (25.9%)
$        3,000   Banco de Galicia 9.00%, 11/01/03..................           2,629
         7,000   Republic of Argentina BOCON, Series 1 DL,
                   (Floating Rate), 3.188%, 4/01/01................           6,072
         5,200   Republic of Argentina Discount Bonds, (Floating
                   Rate), 6.563%, 3/31/23..........................           3,412
     / /26,450   Republic of Argentina Par Bonds, Series L, 5.00%,
                   3/31/23.........................................          15,110
      ++28,000   Republic of Argentina, Series L, "Euro", (Floating
                   Rate), 6.813%, 3/31/05..........................          19,950
                                                                     --------------
                                                                             47,173
                                                                     --------------
  BRAZIL (13.5%)
    BONDS (13.5%)
$    / /17,250   Federative Republic of Brazil Par Bond, Series
                   Z-L, 4.25%, 4/15/24.............................           9,186
      /\26,753   Federative Republic of Brazil, Series C, "Euro",
                   (Floating Rate), PIK, 8.00%, 4/15/14............          15,349
                                                                     --------------
                                                                             24,535
                                                                     --------------
  BULGARIA (0.8%)
    BONDS (0.8%)
$          250   Bulgaria Front Loaded Interest Reduction Bond,
                   Series A, (Floating Rate), 2.00%, 7/28/12.......              75
        #2,983   Bulgaria Interest Arrears Bonds, (Floating Rate),
                   6.75%, 7/28/11..................................           1,387
                                                                     --------------
                                                                              1,462
                                                                     --------------
  ECUADOR (3.3%)
    BONDS (3.3%)
$        5,000   Republic of Ecuador Discount Bonds, "Euro",
                   (Floating Rate), 6.813%, 2/28/25................           2,534
          #181   Republic of Ecuador Discount Bonds, (Floating
                   Rate), 6.813%, 2/28/25..........................              92
         1,900   Republic of Ecuador IE Bonds, (Floating Rate),
                   6.50%, 12/21/04.................................           1,159
      / /4,000   Republic of Ecuador Par Bond, "Euro", 3.00%,
                   3/01/25.........................................           1,460
         2,043   Republic of Ecuador PDI Bonds, "Euro", (Floating
                   Rate), PIK, 6.813%, 3/01/15.....................             684
                                                                     --------------
                                                                              5,929
                                                                     --------------
 
<CAPTION>
     FACE
    AMOUNT                                                               VALUE
    (000)                                                                (000)
<C>              <S>                                                 <C>
- ------------------------------------------------------------
  MEXICO (7.8%)
    BONDS (7.8%)
   MXP  19,092   Banamex Pagare Discount Bond 4/03/97..............  $        1,568
        32,143   Banamex Pagare Discount Bond 10/09/97.............           2,293
$        5,000   Mexican Discount Bond, Series A, (Floating Rate),
                   6.766%, 12/31/19, (Value Recovery Rights
                   Attached).......................................           3,613
         5,000   Mexican Discount Bond, Series B, (Floating Rate),
                   6.766%, 12/31/19, (Value Recovery Rights
                   Attached).......................................           3,613
        #4,200   Petroleos Mexicanos, 8.625%, 12/01/23.............           3,150
                                                                     --------------
                                                                             14,237
                                                                     --------------
  MOROCCO (7.8%)
    LOAN AGREEMENTS (7.8%)
$      ~21,000   Kingdom of Morocco Restructuring and Consolidating
                   Agreement, Tranche A, (Floating Rate), 1/01/09
                   (Participation: Goldman Sachs, Lehman Brothers,
                   Paribas, Salomon Brothers)......................          14,254
                                                                     --------------
  NIGERIA (1.5%)
    BONDS (1.5%)
$        5,500   Nigeria Par Bonds, 6.25%, 11/15/20 (Warrants
                   Attached).......................................           2,709
                                                                     --------------
  PANAMA (5.9%)
    LOAN AGREEMENTS (5.9%)
$   p###14,313   Republic of Panama Loans..........................          10,735
                                                                     --------------
  POLAND (1.8%)
    NOTE (1.8%)
$      ##3,121   Republic of Poland Note, Zero Coupon, 2/28/96.....           3,211
                                                                     --------------
  RUSSIA (15.4%)
    LOAN AGREEMENTS (15.4%)
$     ++15,000   Bank for Foreign Economic Affairs, (Floating
                   Rate)...........................................           5,119
   DEM++86,500   Bank for Foreign Economic Affairs, (Floating
                   Rate)...........................................          22,923
                                                                     --------------
                                                                             28,042
                                                                     --------------
  VENEZUELA (3.5%)
    BONDS (3.5%)
$       11,500   Republic of Venezuela Debt Conversion Bonds,
                   Series DL, (Floating Rate), 6.563%, 12/18/07....           6,339
                                                                     --------------
TOTAL DEBT INSTRUMENTS (Cost $152,483).............................         164,756
                                                                     --------------
SHORT TERM INVESTMENTS (8.7%)
  MEXICO (8.7%)
    BILLS (8.7%)
   MXP  20,000   Mexican Cetes, Zero Coupon, 1/18/96...............           2,535
        21,716   Mexican Cetes, Zero Coupon, 2/08/96...............           2,683
         7,298   Mexican Cetes, Zero Coupon, 2/22/96...............             887
        19,994   Mexican Cetes, Zero Coupon, 7/18/96...............           2,079
        41,820   Mexican Cetes, Zero Coupon, 8/08/96...............           4,260
        35,000   Mexican Cetes, Zero Coupon, 9/26/96...............           3,404
                                                                     --------------
TOTAL SHORT-TERM INVESTMENTS (Cost $20,430)........................          15,848
                                                                     --------------
TOTAL INVESTMENTS (99.3%) (Cost $172,913)..........................         180,604
                                                                     --------------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Emerging Markets Debt Portfolio
 
                                       92
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE EMERGING MARKETS DEBT PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                    AMOUNT
- ------------------------------------------------------------         (000)
OTHER ASSETS (35.7%)
<S>                                                 <C>           <C>
  Interest Receivable.............................  $     2,819
  Receivable for Investments Sold.................       37,950
  Collateral on Deposit with Broker...............       24,039
  Receivable due from Broker......................        5,000
  Receivable for Portfolio Shares Sold............           63
  Other...........................................           12   $    69,883
                                                    -----------
LIABILITIES (-35.0%)
  Securities Sold Short, at Value (Proceeds         $   (26,242)
   $24,470).......................................
  Payable for Investments Purchased...............      (26,106)
  Payable for Reverse Repurchase Agreement........      (12,225)
  Bank Overdraft..................................       (2,755)
  Interest Payable on Securities Sold Short.......         (692)
  Investment Advisory Fees Payable................         (443)
  Custodian Fees Payable..........................          (50)
  Administrative Fees Payable.....................          (25)
  Payable for Portfolio Shares Redeemed...........           (2)
  Other Liabilities...............................          (69)      (68,609)
                                                    -----------   -----------
NET ASSETS (100%)..............................................   $   181,878
                                                                  -----------
                                                                  -----------
NET ASSET VALUE, OFFERING AND REDEMPTION PRICE PER SHARE
  Applicable to 21,172,632 outstanding $.001 par value shares
  (authorized 500,000,000 shares)..............................         $8.59
                                                                  -----------
                                                                  -----------
</TABLE>
 
- ------------------------------------------------------------
 
<TABLE>
<S>        <C>        <C>
)             --      Security is expected to be received in connection
                      with the restructuring of the Panama loan owned by
                      the Portfolio.
++            --      Non-income producing security - in default
++            --      Denotes all or a portion of securities subject to
                      repurchase under Reverse Repurchase Agreements as of
                      December 31, 1995 -- See Note A-4 to Financial
                      Statements.
#             --      144A security -- certain conditions for public sale
                      may exist.
##            --      Securities redemption value is linked to the
                      Republic of Poland Treasury Bill maturing 2/28/96
                      and to the value of the Polish Zloty and Deutsche
                      Mark at maturity.
###           --      Under restructuring at December 31, 1995 -- see Note
                      A-8 to Financial Statements.
***           --      Security is valued at cost. See Note A-1.
/ /           --      Step Bond -- coupon rate increases in increments to
                      maturity. Rate disclosed is as of December 31, 1995.
                      Maturity date disclosed is the ultimate maturity.
~             --      Participation interests were acquired through the
                      financial institutions indicated parenthetically.
/\            --      4.00% of 8.00% represents amount paid in cash. The
                      remainder is payment-in-kind. Cash payment rate
                      increases in increments to maturity.
p             --      Issuer is making partial interest payments.
PDI           --      Past Due Interest
PIK           --      Payment-In-Kind. Income may be paid in additional
                      securities or cash at the discretion of the issuer.
DEM           --      Deutsche Mark
MXP           --      Mexican Peso
Floating Rate -- Interest rate changes on these instruments are based on
changes in a designated base rate. The rates shown are those in effect at
December 31, 1995.
</TABLE>
 
<TABLE>
<CAPTION>
   FACE
  AMOUNT                                                          VALUE
  (000)                                                           (000)
<C>         <S>                                                 <C>
- ------------------------------------------------------------
SECURITIES SOLD SHORT (NOTE A-9)
  MEXICO
    BONDS
$   20,000  United Mexican States Aztec Bonds (Floating Rate)
              7.609%, 3/31/08 (Proceeds $16,900)..............  $   18,000
     5,000  United Mexican States Discount Bond, Series D,
              (Floating Rate), 6.547%, 12/31/19 (Value
              Recovery Rights Attached) (Proceeds $3,500).....       3,613
                                                                ----------
                                                                    21,613
                                                                ----------
  PANAMA
    BONDS
  #) 2,000  Republic of Panama Interest Reduction Bond,
              12/29/49 (Proceeds $820)........................         905
                                                                ----------
  VENEZUELA
    BONDS
     6,500  Republic of Venezuela, Par Bond, Series A,
              (Floating Rate), 6.75%, 3/31/20 (Oil Warrants
              Attached) (Proceeds $3,250).....................       3,724
                                                                ----------
            (Total Proceeds $24,470)..........................  $   26,242
                                                                ----------
                                                                ----------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                 Emerging Markets Debt Portfolio
 
                                       93
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE FIXED INCOME PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
   FACE
  AMOUNT                                                          VALUE
  (000)                                                           (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
FIXED INCOME SECURITIES (83.3%)
  U.S. GOVERNMENT AND AGENCY OBLIGATIONS (37.8%)
    U.S. Treasury Notes (12.1%)
$    7,000  8.25%, 7/15/98....................................  $    7,492
    10,000  6.25%, 5/31/00....................................      10,336
     2,000  7.25%, 8/15/04....................................       2,224
                                                                ----------
                                                                    20,052
                                                                ----------
    Federal Home Loan Mortgage Corporation (4.4%)
        14  13.00%, 9/01/10...................................          16
     6,868  9.00%, 1/01/25....................................       7,227
                                                                ----------
                                                                     7,243
                                                                ----------
    Government National Mortgage Association (21.3%)
         9  11.00%, 12/15/15..................................          10
        16  10.00%, 5/15/19...................................          17
     7,976  6.00%, 2/15/24....................................       7,757
     7,159  8.00%, 3/15/24....................................       7,459
    19,745  7.00%, 5/15/24....................................      19,980
                                                                ----------
                                                                    35,223
                                                                ----------
  TOTAL U.S. GOVERNMENT AND AGENCY OBLIGATIONS................      62,518
                                                                ----------
  FOREIGN GOVERNMENT AND AGENCY OBLIGATIONS (14.9%)
     5,000  Republic of Italy 6.875%, 9/27/23.................       4,883
     5,000  Treuhandanstalt 6.50%, 4/23/03....................       3,635
    22,100  Treuhandanstalt 6.75%, 5/13/04....................      16,171
                                                                ----------
  TOTAL FOREIGN GOVERNMENT AND AGENCY OBLIGATIONS.............      24,689
                                                                ----------
  CORPORATE BONDS AND NOTES (24.9%)
    FINANCE (24.9%)
     7,500  CCP Insurance 10.50%, 12/15/04....................       8,171
    #7,500  Farmers Insurance 8.625%, 5/01/24.................       7,781
     5,000  Ford Motor Credit Co. 6.25%, 11/08/00.............       5,068
     5,000  General Motors Acceptance Corp. 7.375%, 6/22/00...       5,284
     5,000  Goldman Sachs Group 7.80%, 7/15/02................       5,343
     3,000  John Hancock 7.375%, 2/15/24......................       3,002
     3,000  Metropolitan Life Insurance 7.80%, 11/01/25.......       3,125
     3,000  USX Corp. 9.125%, 1/15/13.........................       3,449
                                                                ----------
  TOTAL CORPORATE BONDS AND NOTES.............................      41,223
                                                                ----------
 
<CAPTION>
   FACE
  AMOUNT                                                          VALUE
  (000)                                                           (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
  ASSET BACKED SECURITIES (5.7%)
$        4  Case Equipment Loan Trust, 92-A 5.40%, 6/15/98....  $        4
        26  Federal Home Loan Mortgage Corp., REMIC 16-B
              10.00%, 10/15/19................................          26
        19  Federal National Mortgage Association, REMIC
              92-59F, (Floating Rate), 6.243%, 8/25/06........          19
       100  Ford Credit Auto Loan Master Trust, 92-1A 6.875%,
              1/15/99.........................................         101
         7  General Motors Acceptance Corp. Trust, 92-DA
              5.55%, 5/15/97..................................           7
     4,001  Resolution Trust Corp., Series 1991-M5, Class A,
              9.00%, 3/25/17..................................       4,171
     5,000  Standard Credit Card Trust 6.75%, 6/07/00.........       5,136
                                                                ----------
  TOTAL ASSET BACKED SECURITIES...............................       9,464
                                                                ----------
TOTAL FIXED INCOME SECURITIES (Cost $129,833).................     137,894
                                                                ----------
SHORT-TERM INVESTMENT (15.2%)
  REPURCHASE AGREEMENT (15.2%)
    25,181  Goldman Sachs & Co., 5.83%, dated 12/29/95, due
              1/02/96, to be repurchased at $25,197,
              collateralized by $18,310 United States Treasury
              Bonds, 9.25%, due 2/15/16, valued at $25,707
              (Cost $25,181)..................................      25,181
                                                                ----------
TOTAL INVESTMENTS (98.5%) (Cost $155,014).....................     163,075
                                                                ----------
</TABLE>
 
<TABLE>
<S>                                                 <C>         <C>
OTHER ASSETS (1.6%)
  Cash............................................  $        1
  Interest Receivable.............................       2,314
  Net Unrealized Gain on Forward Foreign Currency          233
   Exchange Contracts.............................
  Receivable for Portfolio Shares Sold............          39
  Other...........................................          14       2,601
                                                    ----------
LIABILITIES (-0.1%)
  Investment Advisory Fees Payable................         (94)
  Administrative Fees Payable.....................         (23)
  Custodian Fees Payable..........................          (4)
  Payable for Portfolio Shares Redeemed...........          (1)
  Other Liabilities...............................         (27)       (149)
                                                    ----------  ----------
NET ASSETS (100%).............................................  $  165,527
                                                                ----------
                                                                ----------
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 15,306,696 outstanding $.001 par value shares
  (authorized 500,000,000 shares).............................      $10.81
                                                                ----------
                                                                ----------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                          Fixed Income Portfolio
 
                                       97
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE FIXED INCOME PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
 
FORWARD FOREIGN CURRENCY EXCHANGE CONTRACT INFORMATION:
  Under  the  terms  of  forward foreign  currency  exchange  contracts  open at
  December 31, 1995,  the Portfolio  is obligated to  deliver or  is to  receive
  foreign currency in exchange for U.S. dollars as indicated below:
 
<TABLE>
<CAPTION>
                                          IN                        NET
  CURRENCY                             EXCHANGE                 UNREALIZED
 TO DELIVER     VALUE    SETTLEMENT      FOR         VALUE      GAIN (LOSS)
   (000)        (000)       DATE        (000)        (000)         (000)
- ------------  ---------  ----------  ------------  ---------  ---------------
<S>           <C>        <C>         <C>           <C>        <C>
  DEM 23,100  $  16,110   1/19/96    U.S.$ 16,360  $  16,360     $     250
U.S.$ 16,131     16,131   1/19/96      DEM 23,100     16,110           (21)
  DEM 28,500     20,011   6/07/96    U.S.$ 20,015     20,015             4
              ---------                            ---------         -----
              $  52,252                            $  52,485     $     233
              ---------                            ---------         -----
              ---------                            ---------         -----
</TABLE>
 
- ------------------------------------------------------------
 
<TABLE>
<S>        <C>        <C>
#          --         144A Security. -- Certain conditions for public
                      sale may exist.
REMIC      --         Real Estate Mortgage Investment Conduit
DEM        --         Deutsche Mark
Floating Rate -- Interest rate changes on these instruments are based
 on changes in a designated base rate. The rates shown are those in
 effect on December 31, 1995.
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Fixed Income Portfolio
 
                                       98
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE GLOBAL FIXED INCOME PORTFOLIO
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
      FACE
     AMOUNT                                                                 VALUE
     (000)                                                                  (000)
- ------------------------------------------------------------
<C>                <S>                                                 <C>
FIXED INCOME SECURITIES (95.7%)
  AUSTRALIAN DOLLAR (1.0%)
    GOVERNMENT BONDS (1.0%)
    AUD    1,300   Government of Australia 9.50%, 8/15/03............  $          1,044
                                                                               --------
  BRITISH POUND (5.7%)
    GOVERNMENT BONDS (5.7%)
    GBP    3,800   United Kingdom Treasury 7.00%, 11/06/01...........             5,907
                                                                               --------
  CANADIAN DOLLAR (5.0%)
    EUROBONDS (2.6%)
    CAD    1,500   British Columbia Province 7.75%, 6/16/03..........             1,131
           2,100   Export-Import Bank of Japan 7.75%, 10/08/02.......             1,588
                                                                               --------
                                                                                  2,719
                                                                               --------
    GOVERNMENT BONDS (2.4%)
             500   Government of Canada 7.50%, 9/01/00...............               380
           2,700   Government of Canada 7.50%, 12/01/03..............             2,039
                                                                               --------
                                                                                  2,419
                                                                               --------
                                                                                  5,138
                                                                               --------
  DANISH KRONE (5.8%)
    GOVERNMENT BONDS (5.8%)
    DKK   15,000   Kingdom of Denmark 8.00%, 11/15/01................             2,890
           9,500   Kingdom of Denmark 7.00%, 12/15/04................             1,703
           7,000   Kingdom of Denmark 8.00%,
                     3/15/06.........................................             1,328
                                                                               --------
                                                                                  5,921
                                                                               --------
  DEUTSCHE MARK (15.6%)
    GOVERNMENT BONDS (15.6%)
     DEM   5,200   German Unity Bond 8.00%, 1/21/02..................             4,087
           7,750   Treuhandanstalt 6.875%, 6/11/03...................             5,746
           8,500   Treuhandanstalt 6.75%, 5/13/04....................             6,219
                                                                               --------
                                                                                 16,052
                                                                               --------
  FRENCH FRANC (6.8%)
    GOVERNMENT BONDS (6.8%)
    FRF   24,500   French Treasury Bill 7.75%, 4/12/00...............             5,363
           3,500   French Treasury Bill 7.00%, 10/12/00..............               748
           4,250   Republic of France 7.00%, 10/12/00................               908
                                                                               --------
                                                                                  7,019
                                                                               --------
  IRISH POUND (1.6%)
    GOVERNMENT BONDS (1.6%)
    IEP      950   Irish Government 9.25%, 7/11/03...................             1,696
                                                                               --------
  ITALIAN LIRA (4.0%)
    GOVERNMENT BONDS (4.0%)
   ITL 6,400,000   Republic of Italy Treasury Bond 10.50%,
                     11/01/00........................................             4,062
                                                                               --------
 
<CAPTION>
      FACE
     AMOUNT                                                                 VALUE
     (000)                                                                  (000)
- ------------------------------------------------------------
<C>                <S>                                                 <C>
  JAPANESE YEN (8.0%)
    EUROBONDS (4.6%)
   JPY   425,000   International Bank for Reconstruction &
                     Development 4.75%, 12/20/04.....................  $          4,703
                                                                               --------
    GOVERNMENT BONDS (3.4%)
         300,000   Japan Development Bank 6.50%, 9/20/01.............             3,546
                                                                               --------
                                                                                  8,249
                                                                               --------
  NETHERLANDS GUILDER (2.0%)
    GOVERNMENT BONDS (2.0%)
    NLG    3,000   Netherlands Government 7.75%, 1/15/00.............             2,061
                                                                               --------
  NEW ZEALAND DOLLAR (1.6%)
    GOVERNMENT BONDS (1.6%)
    NZD    1,800   New Zealand Government 8.00%, 7/15/98.............             1,184
             750   New Zealand Government 6.50%, 2/15/00.............               475
                                                                               --------
                                                                                  1,659
                                                                               --------
  SPANISH PESETA (5.1%)
    GOVERNMENT BONDS (5.1%)
   ESP   612,000   Spanish Government 10.30%, 6/15/02................             5,216
                                                                               --------
  SWEDISH KRONA (2.8%)
    GOVERNMENT BONDS (2.8%)
    SEK   17,500   Swedish Government 10.25%, 5/05/00................             2,829
                                                                               --------
  UNITED STATES DOLLAR (30.7%)
    CORPORATE BONDS AND NOTES (6.2%)
  U.S.$    ++998   Asset Securitization Corp. 7.10%, 8/13/29.........             1,044
             500   Goldman Sachs 6.20%, 2/15/01......................               498
             700   John Hancock 7.375%, 2/15/24......................               701
             898   LB Commercial Conduit Mortgage Trust 7.144%,
                     8/25/04.........................................               937
            #600   Metropolitan Life Insurance 7.45%, 11/01/23.......               588
             600   Prudential Insurance Co. 8.30%, 7/01/25...........               644
           2,000   UCFC CMO, Series 1995-C1, Class A3, 6.775%,
                     11/10/17........................................             2,018
                                                                               --------
                                                                                  6,430
                                                                               --------
    EUROBONDS (0.5%)
             500   Statens Bostads 8.50%, 5/30/97....................               519
                                                                               --------
    U.S. GOVERNMENT AND AGENCY OBLIGATIONS (24.0%)
      U.S. TREASURY BONDS
           ++545   10.75%, 8/15/05...................................               750
         ++1,280   8.125%, 8/15/19...................................             1,610
      U.S. TREASURY NOTES
           ++650   5.00%, 1/31/99....................................               645
         ++2,030   7.75%, 11/30/99...................................             2,199
           ++890   6.25%, 2/15/03....................................               929
           ++675   7.25%, 5/15/04....................................               751
         ++2,800   7.50%, 2/15/05....................................             3,178
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
- --------------------------------------------------------------------------------
Global Fixed Income Portfolio
 
                                      102
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE GLOBAL FIXED INCOME PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
      FACE
     AMOUNT                                                                 VALUE
     (000)                                                                  (000)
- ------------------------------------------------------------
<C>                <S>                                                 <C>
      U.S. TREASURY STRIPS
 U.S.$ ++/\1,600   2/15/98, Principal Only...........................  $          1,434
      GOVERNMENT NATIONAL MORTGAGE ASSOCIATION
           ++249   ARM Pool #179778 8.00%, 5/15/02...................               259
        +++2,500   7.00%, 1/15/26....................................             2,525
        +++8,250   8.50%, 1/15/26....................................             8,663
        +++1,700   6.00%, 1/20/26....................................             1,717
                                                                               --------
                                                                                 24,660
                                                                               --------
                                                                                 31,609
                                                                               --------
TOTAL FIXED INCOME SECURITIES (Cost $95,076).........................            98,462
                                                                               --------
SHORT-TERM INVESTMENT (13.7%)
  REPURCHASE AGREEMENT (13.7%)
          14,105   The Chase Manhattan Bank, N.A. 5.35%, dated
                     12/29/95, due 1/02/96, to be repurchased at
                     $14,113 collateralized by $10,890 United States
                     Treasury Bonds, 10.75%, due 5/15/03 valued at
                     $14,388 (Cost $14,105)..........................            14,105
                                                                               --------
  FOREIGN CURRENCY (0.1%)
   JPY    10,094   Japanese Yen (Cost $99)...........................                99
                                                                               --------
TOTAL INVESTMENTS (109.5%) (Cost $109,280)...........................           112,666
                                                                               --------
</TABLE>
 
<TABLE>
<S>                                                 <C>                <C>
OTHER ASSETS (3.5%)
  Cash............................................  $            531
  Interest Receivable.............................             2,496
  Receivable for Portfolio Shares Sold............               411
  Net Unrealized Gain on Forward Foreign Currency
   Exchange Contracts.............................               132
  Foreign Withholding Tax Reclaim Receivable......                 9
  Other...........................................                 9              3,588
                                                            --------
LIABILITIES (-13.0%)
  Payable for Investments Purchased...............           (12,882)
  Bank Overdraft..................................              (411)
  Investment Advisory Fees Payable................               (53)
  Administrative Fees Payable.....................               (14)
  Custodian Fees Payable..........................               (12)
  Other Liabilities...............................               (30)           (13,402)
                                                            --------           --------
NET ASSETS (100%)...................................................   $        102,852
                                                                               --------
                                                                               --------
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 9,164,317 outstanding $.001 par value shares
  (authorized 500,000,000 shares)....................................            $11.22
                                                                       ----------------
                                                                       ----------------
 
FORWARD FOREIGN CURRENCY EXCHANGE CONTRACT INFORMATION:
  Under the terms of forward foreign currency exchange contracts open at December 31,
  1995, the Portfolio is obligated to deliver or is to receive foreign currency in
  exchange for U.S. dollars as indicated below:
</TABLE>
 
<TABLE>
<CAPTION>
                                                                     NET
CURRENCY TO                           IN EXCHANGE                UNREALIZED
  DELIVER       VALUE    SETTLEMENT       FOR         VALUE      GAIN (LOSS)
   (000)        (000)       DATE         (000)        (000)         (000)
- ------------  ---------  -----------  ------------  ---------  ---------------
<S>           <C>        <C>          <C>           <C>        <C>
JPY 10,094    $      98     1/04/96     U.S.$   98  $      98     $      --
NLG 5,600         3,497     2/13/96    U.S.$ 3,530      3,530            33
U.S.$ 1,559       1,559     2/13/96      NLG 2,500      1,562             3
CAD 2,500         1,832     2/14/96    U.S.$ 1,845      1,845            13
JPY 160,000       1,559     2/14/96    U.S.$ 1,620      1,620            61
U.S.$  794          794     2/14/96     JPY 80,000        780           (14)
DEM 5,000         3,491     2/20/96    U.S.$ 3,571      3,571            80
DEM 5,000         3,494     3/06/96    U.S.$ 3,498      3,498             4
FRF 14,000        2,860     3/07/96    U.S.$ 2,812      2,812           (48)
              ---------                             ---------         -----
              $  19,184                             $  19,316     $     132
              ---------                             ---------         -----
              ---------                             ---------         -----
</TABLE>
 
- ------------------------------------------------------------
 
<TABLE>
<S>        <C>        <C>
+++           --      Security is subject to delayed delivery -- see Note
                      A-7.
#             --      144A Security -- Certain conditions for public sale
                      may exist.
/\            --      Stripped securities represent the splitting of cash
                      flows into several classes which vary by the
                      proportion of principal and interest paid. Holders
                      are entitled to the portion of the payments on the
                      certificate representing interest only or principal
                      only.
++            --      Security was pledged as collateral for delayed
                      delivery securities.
CMO           --      Collateralized Mortgage Obligation
</TABLE>
 
- ------------------------------------------------------------
         SUMMARY OF FIXED INCOME SECURITIES BY INDUSTRY CLASSIFICATION
                                  (UNAUDITED)
 
<TABLE>
<CAPTION>
                                              VALUE     PERCENT OF
INDUSTRY                                      (000)     NET ASSETS
- --------------------------------------------------------------------
<S>                                         <C>        <C>
Finance...................................  $  13,240        12.8%
Foreign Government and Agency
Obligations...............................     60,562        58.9
U.S. Government and Agency Obligations....     24,660        24.0
                                            ---------         ---
                                            $  98,462        95.7%
                                            ---------         ---
                                            ---------         ---
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
- --------------------------------------------------------------------------------
                                                   Global Fixed Income Portfolio
 
                                      103
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE HIGH YIELD PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
   FACE
  AMOUNT                                                         VALUE
  (000)                                                          (000)
      ------------------------------------------------------------
<C>         <S>                                                 <C>
CORPORATE BONDS AND NOTES (89.6%)
  BROADCAST-RADIO & TELEVISION (21.5%)
$    2,250  Ackerley Communications, Inc., Series A, 10.75%,
              10/01/03........................................  $  2,408
       750  ACT III Broadcasting, Inc., 10.25%, 12/15/05......       769
     1,000  Cablevision Systems Corp., 10.75%, 4/01/04........     1,058
     1,250  Continental Cablevision, Inc., 9.50%, 8/01/13.....     1,328
       250  Fundy Cable Ltd., 11.00%, 11/15/05................       261
  / /1,600  Helicon Group, Series B, 9.00%, 11/01/03..........     1,544
       400  Heritage Media, 11.00%, 10/01/02..................       421
       500  Katz Corp., 12.75%, 11/15/02......................       525
  / /2,400  Marcus Cable Co., 0.00%, 12/15/05.................     1,632
     1,350  New World Communications Group Holding Corp., Zero
              Coupon, Series B, 6/15/99.......................       935
       900  Rogers Cablesystems Ltd., 11.00%, 12/01/15........       968
     1,500  Viacom, Inc., 8.00%, 7/07/06......................     1,526
                                                                --------
                                                                  13,375
                                                                --------
  CHEMICALS (3.4%)
       750  Harris Chemical, 10.75%, 10/15/03.................       683
     1,000  Plastic Specialties & Technologies, Inc., 11.25%,
              12/01/03........................................       920
       500  Sherritt, Inc., 10.50%, 3/31/14...................       533
                                                                --------
                                                                   2,136
                                                                --------
  COAL, GAS & OIL (0.4%)
        33  Columbia Gas Systems, Inc., Series A, 6.39%,
              11/28/00........................................        33
        33  Columbia Gas Systems, Inc., Series B, 6.61%,
              11/28/02........................................        33
        33  Columbia Gas Systems, Inc., Series C, 6.80%,
              11/28/05........................................        33
        33  Columbia Gas Systems, Inc., Series D, 7.05%,
              11/28/07........................................        33
        33  Columbia Gas Systems, Inc., Series E, 7.32%,
              11/28/10........................................        33
        33  Columbia Gas Systems, Inc., Series F, 7.42%,
              11/28/15........................................        33
        33  Columbia Gas Systems, Inc., Series G, 7.62%,
              11/28/25........................................        33
                                                                --------
                                                                     231
                                                                --------
  ENTERTAINMENT & LEISURE (4.4%)
       886  Kloster Cruise Ltd., 13.00%, 5/01/03..............       673
 #/ /2,000  Six Flags Theme Park, Inc., 0.00%, 6/15/05........     1,560
       500  Stena AB, 10.50%, 12/15/05........................       510
                                                                --------
                                                                   2,743
                                                                --------
  ENVIRONMENTAL CONTROLS (1.9%)
    #1,200  Norcal Waste Systems, 12.50%, 11/15/05............     1,209
                                                                --------
 
<CAPTION>
   FACE
  AMOUNT                                                         VALUE
  (000)                                                          (000)
      ------------------------------------------------------------
<C>         <S>                                                 <C>
 
  FINANCIAL SERVICES (6.9%)
   #$1,191  GPA Equipment Trust, 9.125%, 12/02/96.............  $  1,179
       550  GPA Investments, 6.40%, 11/19/98..................       451
    / /500  PM Holdings Corp., 0.00%, 9/01/05.................       257
       500  Rapp International Finance, 13.25%, 12/15/05......       491
     1,000  Terra Nova Holdings, 10.75%, 7/01/05..............     1,091
     1,189  Tiphook Finance Corp., 8.00%, 3/15/00.............       826
                                                                --------
                                                                   4,295
                                                                --------
  FOOD (1.7%)
     1,150  Pilgrim's Pride Corp., 10.875%, 8/01/03...........     1,044
                                                                --------
  FOOD SERVICE & LODGING (2.8%)
     2,250  Family Restaurant Inc., 9.75%, 2/01/02............     1,238
       500  United Meridian Corp., 10.375%, 10/15/05..........       526
                                                                --------
                                                                   1,764
                                                                --------
  GAMING & LODGING (2.0%)
       500  Casino America, 11.50%, 11/15/01..................       462
       250  Grand Casinos Inc., 10.125%, 12/01/03.............       261
       575  Louisiana Casino Cruises, 11.50%, 12/01/98........       552
                                                                --------
                                                                   1,275
                                                                --------
  HEALTH CARE SUPPLIES & SERVICES (2.6%)
     1,000  Quorum Health Group, Inc., 8.75%, 11/01/05........     1,035
       500  Tenet Healthcare Corp., 10.125%, 3/01/05..........       554
                                                                --------
                                                                   1,589
                                                                --------
  MATERIALS (3.4%)
       500  IMC Fertilizer, 9.25%, 10/01/00...................       526
     1,500  IMC Fertilizer, 9.45%, 12/15/11...................     1,599
                                                                --------
                                                                   2,125
                                                                --------
  METALS (2.0%)
       750  Algoma Steel Inc., (Yankee Bond), 12.375%,
              7/15/05.........................................       675
       650  Sheffield Steel Corp., 12.00%, 11/01/01...........       566
                                                                --------
                                                                   1,241
                                                                --------
  MULTI-INDUSTRY (0.4%)
      #250  Howmet Corp., 10.00%, 12/01/03....................       260
                                                                --------
  PACKAGING & CONTAINER (5.1%)
       500  Owens-Illinois, Inc., 10.50%, 6/15/02.............       531
     1,500  Owens-Illinois, Inc., 9.95%, 10/15/04.............     1,594
     1,000  Stone Container Corp., 10.75%, 10/01/02...........     1,033
                                                                --------
                                                                   3,158
                                                                --------
  PUBLISHING (1.8%)
       750  Marvel III Holdings Inc., Series B, 9.125%,
              2/15/98.........................................       734
       500  Marvel Parent Holdings, Zero Coupon, 4/15/98......       360
                                                                --------
                                                                   1,094
                                                                --------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
High Yield Portfolio
 
                                      106
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE HIGH YIELD PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
   FACE
  AMOUNT                                                         VALUE
  (000)                                                          (000)
      ------------------------------------------------------------
<C>         <S>                                                 <C>
  REAL ESTATE (0.8%)
     $#500  HMC Acquisition Properties, 9.00%, 12/15/07.......  $    505
                                                                --------
  RETAIL-GENERAL (6.3%)
       750  Grand Union Co., 12.00%, 9/01/04..................       645
      #800  Host Marriot Travel Plaza, Series B, 9.50%,
              5/15/05.........................................       790
     3,000  Southland Corp., 5.00%, 12/15/03..................     2,498
                                                                --------
                                                                   3,933
                                                                --------
  TELECOMMUNICATIONS (9.3%)
  / /3,000  Dial Call Communications, 0.00%, 4/15/04..........     1,710
    / /450  Horizon Cellular Telephone, 0.00%, 10/01/00.......       374
  / /2,250  Nextel Communications, 0.00%, 8/15/04.............     1,221
       400  Paging Network, 10.125%, 8/01/07..................       434
       500  Rogers Communications, Inc., 10.875%, 4/15/04.....       522
     1,500  Telefonica de Argentina, (Yankee Bond), 11.875%,
              11/01/04........................................     1,571
                                                                --------
                                                                   5,832
                                                                --------
  TEXTILES & APPAREL (4.1%)
     1,000  Polysindo Eka Perkasa, (Yankee Bond), 13.00%,
              6/15/01.........................................     1,035
       500  Synthetic Industries, 12.75%, 12/01/02............       494
     1,000  Westpoint Stevens, Inc., 9.375%, 12/15/05.........       992
                                                                --------
                                                                   2,521
                                                                --------
  TRANSPORTATION (2.4%)
      *243  America West Airlines, 6.00%, 3/31/97 (acquired
              1/17/94 Cost $232)..............................       228
     1,500  Venture Holdings, 9.75%, 4/01/04..................     1,253
                                                                --------
                                                                   1,481
                                                                --------
  UTILITIES (6.4%)
     1,478  Beaver Valley Funding Corp., (Lease Obligation
              Bond), 9.00%, 6/01/17...........................     1,247
     1,250  California Energy Co., Inc., 9.875%, 6/30/03......     1,303
     1,400  First PV Funding Corp., (Lease Obligation Bond),
              Series 1986B, 10.15%, 1/15/16...................     1,428
                                                                --------
                                                                   3,978
                                                                --------
TOTAL CORPORATE BONDS AND NOTES (Cost $54,542)................    55,789
                                                                --------
FOREIGN GOVERNMENT BONDS (3.8%)
  BONDS (3.8%)
  / /2,500  Federative Republic of Brazil, Par Bond, Series
              Z-L, 4.25%, 4/15/24.............................     1,313
     1,500  Republic of Argentina, Series L, "Euro" (Floating
              Rate), 6.813%, 3/31/05..........................     1,068
                                                                --------
TOTAL FOREIGN GOVERNMENT BONDS (Cost $2,018)..................     2,381
                                                                --------
<CAPTION>
 
                                                                 VALUE
  SHARES                                                         (000)
      ------------------------------------------------------------
<C>         <S>                                                 <C>
COMMON STOCKS (0.8%)
  BUILDING MATERIALS & COMPONENTS (0.6%)
   +30,331  Walter Industries, Inc............................  $    398
                                                                --------
  FINANCIAL SERVICES (0.0%)
    +1,268  WestFed Holdings, Inc., Class B...................        --
                                                                --------
  FOOD SERVICE & LODGING (0.2%)
    +1,300  Motels of America, Inc............................        98
                                                                --------
  GAMING & LODGING (0.0%)
      +500  Trump Taj Mahal, Class A..........................        10
                                                                --------
TOTAL COMMON STOCKS (Cost $599)...............................       506
                                                                --------
PREFERRED STOCKS (0.1%)
  FINANCIAL SERVICES (0.0%)
     3,239  WestFed Holdings, Inc., Series A..................        --
                                                                --------
  COAL, GAS & OIL (0.1%)
      +925  Columbia Gas Systems, Inc., Series A, 7.89%.......        23
                                                                --------
TOTAL PREFERRED STOCKS (Cost $80).............................        23
                                                                --------
CONVERTIBLE PREFERRED STOCKS (0.0%)
  COAL, GAS & OIL (0.0%)
       566  Columbia Gas Systems, Inc., Series B, 5.22%,
              11/28/00 (Cost $23).............................        22
                                                                --------
<CAPTION>
 
  NO. OF
  RIGHTS
- ----------
<C>         <S>                                                 <C>
RIGHTS (0.0%)
  BROADCAST-RADIO & TELEVISION (0.0%)
  ++35,000  SpectraVision, Inc., expiring 10/08/97 (Cost
              $133)...........................................         2
                                                                --------
<CAPTION>
 
  NO. OF
 WARRANTS
- ----------
<C>         <S>                                                 <C>
WARRANTS (0.6%)
  AEROSPACE & DEFENSE (0.0%)
     +*500  Sabreliner Corp., expiring 4/15/03 (acquired
              6/21/93, cost $10)..............................         3
                                                                --------
  ELECTRICAL EQUIPMENT (0.4%)
  +#28,000  Protection One Alarm, Inc., expiring 4/03/03......       224
                                                                --------
  GAMING & LODGING (0.0%)
   +#2,700  Casino Magic Corp., expiring 10/14/96.............        --
    +1,725  Louisiana Casino Cruises, expiring 12/01/98.......        14
                                                                --------
                                                                      14
                                                                --------
  INSURANCE (0.0%)
      +500  Horace Mann Educators Corp., expiring 4/3/99......         7
                                                                --------
  METALS (0.1%)
    +8,250  Sheffield Steel Corp., expiring 11/01/01..........        41
                                                                --------
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                            High Yield Portfolio
 
                                      107
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE HIGH YIELD PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
  NO. OF                                                         VALUE
 WARRANTS                                                        (000)
      ------------------------------------------------------------
<C>         <S>                                                 <C>
  PACKAGING & CONTAINER (0.0%)
    +1,000  Crown Packaging Holdings, expiring 11/01/03.......  $      8
                                                                --------
  REAL ESTATE (0.1%)
    +1,000  Petro PSC Properties L.P., expiring 6/01/97.......        34
                                                                --------
  TELECOMMUNICATIONS (0.0%)
    +3,000  Dial Page, Inc., expiring 4/25/99.................        --
                                                                --------
TOTAL WARRANTS (Cost $228)....................................       331
                                                                --------
<CAPTION>
  NO. OF
  UNITS
- ----------
<C>         <S>                                                 <C>
UNITS (4.7%)
  BROADCAST-RADIO & TELEVISION (1.2%)
 #/ /1,250  American Telecasting, 14.50%, 8/15/05.............       756
                                                                --------
  GAMING & LODGING (2.0%)
  ++#2,208  Maritime Group Series A, 13.50%, 2/15/97..........       309
       964  Trump Taj Mahal Funding Inc., PIK, 9.375%,
              11/15/99........................................       928
                                                                --------
                                                                   1,237
                                                                --------
  METALS (1.5%)
     1,000  Sheffield Steel Corp. (1st Mortgage Bond + 5
              Common Stock Warrants), 12.00%, 11/01/01........       940
                                                                --------
TOTAL UNITS (Cost $5,131).....................................     2,933
                                                                --------
TOTAL INVESTMENTS (99.6%) (Cost $62,754)......................    61,987
                                                                --------
</TABLE>
 
<TABLE>
  <S>                                                 <C>          <C>
  OTHER ASSETS (1.9%)
    Interest Receivable.............................       $1,144
    Receivable for Portfolio Shares Sold............           32
    Other...........................................            7     1,183
                                                      -----------
  LIABILITIES (-1.5%)
    Bank Overdraft..................................         (598)
    Payable for Portfolio Shares Redeemed...........         (214)
    Investment Advisory Fees Payable................          (70)
    Administrative Fees Payable.....................           (9)
    Custodian Fees Payable..........................           (3)
    Other Liabilities...............................          (31)     (925)
                                                      -----------  --------
  NET ASSETS (100.0%)............................................   $62,245
                                                                   --------
                                                                   --------
  NET ASSET VALUE, OFFERING AND
    REDEMPTION PRICE PER SHARE
    Applicable to 5,951,111 outstanding $.001 par value shares
    (authorized 500,000,000 shares)..............................    $10.46
                                                                   --------
                                                                   --------
</TABLE>
 
<TABLE>
<CAPTION>
       ------------------------------------------------------------
<S>        <C>        <C>
+             --      Non-income producing security
++            --      Non-income producing security -- in default
*             --      Restricted as to public resale. Total value of
                      restricted securities held at December 31, 1995 was
                      $231 or 0.4% of net assets (Total Cost $242).
#             --      144A Security -- Certain conditions for public sale
                      may exist.
/ /           --      Step Bond -- Coupon rate increases in increments to
                      maturity. Rate disclosed is as of December 31, 1995.
                      Maturity date disclosed is the ultimate maturity.
PIK           --      Payment-In-Kind. Income may be paid in additional
                      securities or cash at the discretion of the issuer.
</TABLE>
 
Floating Rate -- Interest rate changes on these instruments are based on changes
in a designated base rate. The rates shown are those in effect on December 31,
1995.
 
At December 31, 1995, approximately 99% of the Portfolio's net assets consisted
of high yield securities rated below investment grade. Investments in high yield
securities are accompanied by a greater degree of credit risk and the risk tends
to be more sensitive to economic conditions than higher rated securities.
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
High Yield Portfolio
 
                                      108
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE MUNICIPAL BOND PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
FACE AMOUNT                                    VALUE
   (000)                                       (000)
- ------------------------------------------------------
<C>           <S>                             <C>
TAX-EXEMPT INSTRUMENTS (98.0%)
  DAILY VARIABLE RATE BONDS (1.5%)
$       400   Platte County, Wyoming,
                Pollution Control Revenue
                Bonds, Series A, 6.00%,
                7/01/14.....................  $    400
        300   Port of Saint Helens, Oregon,
                Pollution Control Revenue
                Bonds, Series A, Portland
                General Electric Co. 5.95%,
                4/01/10.....................       300
                                              --------
TOTAL DAILY VARIABLE RATE BONDS (Cost
$700).......................................       700
                                              --------
  FIXED RATE INSTRUMENTS (96.5%)
      1,000   Connecticut State Special
                Obligation, Tax Revenue
                Bonds, Transportation,
                6.50%, 7/01/09, Prerefunded
                7/01/99 at 102..............     1,096
      1,000   De Kalb County, Georgia,
                General Obligation Bonds,
                7.30%, 1/01/00, Prerefunded
                1/01/97 at 102..............     1,057
      1,000   De Kalb County, Georgia, Water
                & Sewer Revenue Bonds 7.00%,
                10/01/06....................     1,081
      1,000   Delaware Transportation
                Authority, Transportation
                System Revenue Bonds, 6.50%,
                7/01/11, Prerefunded 7/01/01
                at 102......................     1,122
      2,000   Florida State General
                Obligation Bonds, 5.88%,
                6/01/24.....................     2,059
      1,000   Georgia State, General
                Obligation Bonds, Series E,
                6.75%, 12/01/02.............     1,146
        500   Hawaii State, General
                Obligation Bonds, Series BS,
                6.70%, 9/01/97..............       523
      1,000   Hawaii State, General
                Obligation Bonds, Series CJ,
                6.20%, 1/01/12..............     1,079
      1,000   Howard County, Maryland,
                Consolidated Public
                Improvement General
                Obligation Bonds, Series A,
                7.20%, 8/01/03, Prerefunded
                8/01/96 at 102..............     1,041
      1,500   Intermountain Power Agency,
                Utah, Power Supply Revenue
                Bonds, Series D, 8.38%,
                7/01/12.....................     1,621
      1,000   Kentucky State Housing Corp.
                Revenue Bonds, Series A,
                6.00%, 7/01/10..............     1,039
      1,155   Maryland State Department of
                Transportation, Construction
                Revenue Bonds, Second Issue,
                6.80%, 11/01/05, Prerefunded
                11/01/99 at 102.............     1,285
      1,000   Massachusetts State
                Consolidated Loan, Series A,
                7.50%, 3/01/03, Prerefunded
                3/01/00 at 102..............     1,141
        500   Massachusetts State
                Consolidated Loan, Series A,
                7.63%, 6/01/08, Prerefunded
                6/01/01 at 102..............       588
      2,000   Massachusetts State Special
                Obligation Revenue Bonds,
                Series A 6.00%, 6/01/13.....     2,083
      1,625   Michigan State Housing
                Development Authority
                Revenue Bonds, Series A,
                6.75%, 12/01/14.............     1,719
      1,500   Minnesota State General
                Obligation Bonds, 7.00%,
                8/01/99, Prerefunded 8/01/96
                at 100......................     1,530
 
<CAPTION>
FACE AMOUNT                                    VALUE
   (000)                                       (000)
- ------------------------------------------------------
<C>           <S>                             <C>
$     1,590   Minnesota State Infrastructure
                Development, General
                Obligation Bonds, 6.80%,
                8/01/03, Prerefunded 8/01/00
                at 100......................  $  1,762
      1,400   Mississippi State General
                Obligation Bonds, 6.00%,
                2/01/09.....................     1,503
      1,475   Montana State General
                Obligation Bonds, Long Range
                Building Program, Series C,
                6.00%, 8/01/13..............     1,571
      1,000   New Castle County, Delaware,
                General Obligation Bonds,
                6.25%, 10/15/01.............     1,100
      1,000   New York State Local
                Government Assistance Corp.
                Revenue Bonds, Series B,
                7.50%, 4/01/20, Prerefunded
                4/01/01 at 102..............     1,170
        500   Ohio State General Obligation
                Bonds, 6.20%, 8/01/12.......       549
      1,000   Ohio State Housing Finance
                Agency, Residential Mortgage
                Revenue Bonds, Series A-1,
                6.20%, 9/01/14..............     1,038
        525   Pennsylvania State General
                Obligation Bonds, Series A,
                6.50%, 1/01/00..............       568
      1,000   Pennsylvania State Higher
                Educational Facilities
                Authority, Colleges &
                Universities Revenue Bonds,
                6.50%, 9/01/02..............     1,118
      1,000   Redmond, Washington, General
                Obligation Bonds, 5.75%,
                12/01/05....................     1,082
      1,000   Reedy Creek Improvement
                District, Florida, Utility
                Revenue Bonds, Series 91-1,
                6.50%, 10/01/16, Prerefunded
                10/01/01 at 101.............     1,124
      1,400   Rhode Island Depositors
                Economic Protection Corp.,
                Special Obligation Revenue
                Bonds, Series A, 7.25%,
                8/01/21, Prerefunded 8/01/96
                at 102......................     1,458
      1,350   San Antonio, Texas, General
                Obligation Bonds, 6.50%,
                8/01/14.....................     1,484
      1,000   Tulsa, Oklahoma, General
                Obligation Bonds, 6.38%,
                2/01/02.....................     1,106
      1,000   Virginia Beach, Virginia,
                General Obligation Bonds,
                6.00%, 9/01/10..............     1,075
        500   Virginia State Housing
                Development Authority,
                Commonwealth Mortgage
                Revenue Bonds, Series B,
                6.60%, 1/01/12..............       531
      1,000   Virginia State Housing
                Development Authority,
                Commonwealth Mortgage
                Revenue Bonds, Series B,
                6.65%, 1/01/13..............     1,066
      1,000   Washington State General
                Obligation Bonds, Series B,
                6.20%, 6/01/01..............     1,088
      1,500   Washington State General
                Obligation Bonds, Series
                86-D, 8.00%, 9/01/09,
                Prerefunded 9/01/96 at
                100.........................     1,544
        500   Washington Suburban Sanitary
                District, General Obligation
                Revenue Bonds, 6.50%,
                11/01/05, Prerefunded
                11/01/01 at 102.............       565
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
- --------------------------------------------------------------------------------
                                                        Municipal Bond Portfolio
 
                                      111
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE MUNICIPAL BOND PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
FACE AMOUNT                                    VALUE
   (000)                                       (000)
- ------------------------------------------------------
<C>           <S>                             <C>
$       500   Washington Suburban Sanitary
                District, General Obligation
                Revenue Bonds, 6.30%,
                1/01/07, Prerefunded 1/01/02
                at 102......................  $    557
                                              --------
TOTAL FIXED RATE INSTRUMENTS (Cost
$42,634)....................................    44,269
                                              --------
TOTAL TAX-EXEMPT INSTRUMENTS (98.0%) (Cost
$43,334)....................................    44,969
                                              --------
TOTAL INVESTMENTS (98.0%) (Cost $43,334)....    44,969
                                              --------
</TABLE>
 
<TABLE>
<S>                             <C>         <C>
OTHER ASSETS (2.1%)
  Cash........................  $       37
  Interest Receivable.........         922
  Other.......................           1       960
                                ----------
LIABILITIES (-0.1%)
  Investment Advisory Fees
   Payable....................         (11)
  Payable for Portfolio Shares
   Redeemed...................          (7)
  Administrative Fees
   Payable....................          (7)
  Custodian Fees Payable......          (2)
  Other Liabilities...........         (33)      (60)
                                ----------  --------
NET ASSETS (100%).........................  $ 45,869
                                            --------
                                            --------
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 4,422,080 outstanding
  $.001 par value shares (authorized
  500,000,000 shares).....................    $10.37
                                            --------
                                            --------
</TABLE>
 
- ------------------------------------------------
Variable/Floating Rate Instruments. The interest rate changes on these
instruments are based upon a designated base rate. These instruments are payable
on demand and are secured by a letter of credit or other support agreements.
Maturity dates disclosed for Variable/Floating Rate Instruments are the ultimate
maturity dates. The effective maturity dates for such securities are the next
interest reset dates which are seven days or less.
 
Prerefunded Bonds. Outstanding Bonds have been refunded to the first call date
(prerefunded date) by the issuance of new bonds. Principal and interest are paid
from monies escrowed in U.S. Treasury securities. Prerefunded bonds are
generally re-rated AAA due to the Treasury escrow.
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
- --------------------------------------------------------------------------------
Municipal Bond Portfolio
 
                                      112
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE MONEY MARKET PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
   FACE                                                         AMORTIZED
  AMOUNT                                                           COST
  (000)                                                           (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
MONEY MARKET INSTRUMENTS (93.5%)
  U.S. GOVERNMENT AND AGENCY OBLIGATIONS (70.5%)
    AGENCY DISCOUNT NOTES (44.4%)
            Federal Home Loan Bank
$   50,000  6.10%, 1/02/96....................................  $  49,991
    10,000  5.47%, 1/22/96....................................      9,968
    15,000  5.56%, 1/24/96....................................     14,947
    10,000  5.56%, 2/01/96....................................      9,952
    25,000  5.47%, 3/06/96....................................     24,753
            Federal Home Loan Mortgage Corp.
    25,000  5.59%, 1/16/96....................................     24,942
            Federal National Mortgage Corp.
    25,000  5.61%, 1/05/96....................................     24,984
    25,000  5.67%, 1/09/96....................................     24,969
    15,000  5.56%, 1/10/96....................................     14,979
    25,000  5.55%, 1/19/96....................................     24,931
    30,000  5.63%, 1/24/96....................................     29,892
    20,000  5.58%, 1/26/96....................................     19,923
    20,000  5.57%, 2/08/96....................................     19,882
    25,000  5.57%, 2/14/96....................................     24,830
    18,000  5.50%, 2/28/96....................................     17,841
    20,000  5.45%, 4/05/96....................................     19,712
    15,000  5.37%, 4/30/96....................................     14,731
                                                                ----------
                                                                  371,227
                                                                ----------
    AGENCY FLOATING RATE NOTES (23.8%)
            Federal National Mortgage Association
    25,000  5.53%, 11/20/96...................................     24,985
    65,000  5.85%, 9/02/97....................................     65,000
    25,000  5.26%, 6/02/99....................................     25,000
    13,000  5.26%, 7/26/99....................................     12,950
    25,000  5.26%, 9/22/99....................................     25,000
            Student Loan Marketing Association
    46,000  5.40%, 10/30/97...................................     46,053
                                                                ----------
                                                                  198,988
                                                                ----------
    U.S. TREASURY STRIPS (2.3%)
  /\20,000  5/15/96, Principal Only...........................     19,587
                                                                ----------
TOTAL U.S. GOVERNMENT AND AGENCY OBLIGATIONS
  (Cost $589,802).............................................    589,802
                                                                ----------
COMMERCIAL PAPER (11.9%)
  FINANCE (11.9%)
    15,000  Abbey National North America 5.62%, 1/16/96.......     14,965
    10,000  Commerzbank 5.58%, 1/31/96........................      9,954
    35,000  Koch Industries 5.65%, 1/19/96....................     34,901
    20,000  Pfizer, Inc., 5.70%, 1/17/96......................     19,949
    20,000  Pfizer, Inc., 5.70%, 1/19/96......................     19,943
                                                                ----------
TOTAL COMMERCIAL PAPER (Cost $99,712).........................     99,712
                                                                ----------
CORPORATE FLOATING RATE NOTES (3.0%)
  FINANCE (3.0%)
    15,000  General Electric Credit Corp. 5.85%, 2/09/96......     15,000
    10,000  General Electric Credit Corp. 5.85%,
              2/15/96.........................................     10,000
                                                                ----------
TOTAL CORPORATE FLOATING RATE NOTES (Cost $25,000)............     25,000
                                                                ----------
 
<CAPTION>
   FACE                                                         AMORTIZED
  AMOUNT                                                           COST
  (000)                                                           (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
CERTIFICATES OF DEPOSIT (8.1%)
$   30,000  Deutsche Bank (Yankee) 5.64%, 3/08/96.............  $  30,000
    30,000  Rabo Bank, New York (Yankee) 5.75%, 3/06/96.......     30,001
     8,000  Rabo Bank New York (Yankee) 5.93%, 5/16/96........      8,003
                                                                ----------
TOTAL CERTIFICATES OF DEPOSIT (Cost $68,004)..................     68,004
                                                                ----------
TOTAL MONEY MARKET INSTRUMENTS (Cost $782,518)................    782,518
                                                                ----------
<CAPTION>
 
                                                                  AMOUNT
                                                                  (000)
                                                                ----------
<C>         <S>                                                 <C>
SHORT TERM INVESTMENT (6.5%)
  REPURCHASE AGREEMENT (6.5%)
    53,913  Goldman Sachs 5.83%, dated 12/29/95, due 1/02/96,
              to be repurchased at $53,948, collateralized by
              $39,585, United States Treasury Bonds, 10.375%,
              due 11/15/11, valued at $55,023 (Cost
              $53,913)........................................     53,913
                                                                ----------
TOTAL INVESTMENTS (100.0%) (Cost $836,431)....................    836,431
                                                                ----------
</TABLE>
 
<TABLE>
<S>                                                 <C>         <C>
OTHER ASSETS (0.3%)
  Cash............................................  $        1
  Interest Receivable.............................       2,802
  Other...........................................          57       2,860
                                                    ----------
LIABILITIES (-0.3%)
  Dividends Payable...............................      (1,718)
  Investment Advisory Fees Payable................        (638)
  Administrative Fees Payable.....................        (116)
  Custodian Fees Payable..........................         (22)
  Other Liabilities...............................        (104)     (2,598)
                                                    ----------  ----------
NET ASSETS (100%).............................................  $  836,693
                                                                ----------
                                                                ----------
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 836,710,488 outstanding
  $.001 par value shares (authorized 4,000,000,000 shares)....
                                                                     $1.00
                                                                ----------
                                                                ----------
</TABLE>
 
- ------------------------------------------------------------
 
/\ -- Stripped securities represent the splitting of cash flows into several
     classes which vary by the proportion of principal and interest paid.
     Holders are entitled to the portion of the payments on the certificate
     representing interest only or principal only.
 
Floating Rate -- The interest rate changes on these instruments are based on
changes in a designated base rate. The rates shown are those in effect at
December 31, 1995.
 
Maturity dates disclosed for Floating Rate Instruments are the ultimate maturity
dates. The effective maturity dates for such securities are the next interest
reset dates.
 
Interest rates disclosed for Commercial Paper and Agency Discount Notes
represent effective yields at December 31, 1995.
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                          Money Market Portfolio
 
                                      115
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE MUNICIPAL MONEY MARKET PORTFOLIO
 
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
   FACE                                                         AMORTIZED
  AMOUNT                                                           COST
  (000)                                                           (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
TAX-EXEMPT INSTRUMENTS (96.4%)
  FIXED RATE INSTRUMENTS (43.9%)
      NOTES (2.0%)
$   3,400   Charleston, South Carolina, Water & Sewer System
              Revenue, 7.50%, 1/01/14
              Prerefunded 1/01/96 at 102......................  $   3,468
      500   Du Page Water Commission, Illinois, 7.10%,
              3/01/96.........................................        503
    5,000   New York State Urban Development Correctional
              Facilities, 8.00%, 1/01/15 Prerefunded 1/01/96
              at 102..........................................      5,100
                                                                ----------
                                                                    9,071
                                                                ----------
      PUT OPTION BONDS (0.4%)
    1,000   York County, South Carolina, Series B-4, 3.75%,
              9/15/14 (Putable 3/15/96).......................      1,000
    1,000   York County, South Carolina, Series E-2, 3.80%,
              8/15/14 (Putable 2/15/96).......................      1,000
                                                                ----------
                                                                    2,000
                                                                ----------
      TAX & REVENUE ANTICIPATION NOTES (1.6%)
    4,000   Colorado State, 4.50%, 6/27/96, TRANS.............      4,012
    3,000   Texas State, Series 95A, 4.75%, 8/30/96, TRANS....      3,013
                                                                ----------
                                                                    7,025
                                                                ----------
      COMMERCIAL PAPER (39.9%)
    3,000   Beaver County, Pennsylvania, Industrial
              Development Authority, Duquesne Light, Series
              90, 3.75%, 2/14/96..............................      3,000
    4,000   Burke County, Georgia, Development Authority,
              Oglethorpe, Series 92A, 3.80%, 2/15/96..........      4,000
    2,000   Burlington, Kansas, Kansas City Power & Light Co.,
              Series 87A, 3.70%, 2/20/96......................      2,000
    2,700   Burlington, Kansas, Kansas City Power & Light Co.,
              Series 87B, 3.70%, 2/20/96......................      2,700
    3,500   City of Austin, Texas, Series A, 3.55%, 3/28/96...      3,500
    4,530   City of Dallas, Texas, 3.80%, 2/05/96.............      4,530
    6,000   City of Honolulu, Hawaii, 3.75%, 2/12/96..........      6,000
    1,900   City of San Antonio, Texas, 3.70%, 2/12/96........      1,900
   10,000   Commonwealth of Massachusetts, Series A, 3.70%,
              1/09/96.........................................     10,000
    5,000   Commonwealth of Virginia, 3.83%, 1/10/96..........      5,000
    1,200   Connecticut State Health & Education Facilities
              Authority, Yale University, Series N, 3.70%,
              1/12/96.........................................      1,200
    2,525   Gainesville, Florida, Series C, 3.85%, 1/30/96....      2,525
    4,000   Georgia Municipal Gas Authority, 3.75%, 2/23/96...      4,000
    2,000   Illinois Development Finance Authority, Series
              93A, 3.65%, 2/16/96.............................      2,000
    1,000   Illinois Health & Education, Series 89A, 3.75%,
              2/22/96.........................................      1,000
    4,000   Independence, Missouri, Water Utility Revenue,
              3.75%, 2/12/96..................................      4,000
 
<CAPTION>
   FACE                                                         AMORTIZED
  AMOUNT                                                           COST
  (000)                                                           (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
$   3,100   Intermountain Power Agency, Utah, Series E 3.75%,
              2/07/96.........................................  $   3,100
    2,400   Intermountain Power Agency, Utah, Series E, 3.75%,
              2/23/96.........................................      2,400
      700   Intermountain Power Agency, Utah, Series F2,
              3.90%, 1/11/96..................................        700
    1,500   Intermountain Power Agency, Utah, Series 85F,
              3.90%, 1/11/96..................................      1,500
    3,100   Jacksonville, Florida, Electric Authority, Series
              C-1, 3.50%, 3/07/96.............................      3,100
    7,700   Jacksonville, Florida, Electric Authority, 3.65%,
              2/16/96.........................................      7,700
    3,600   Jasper County, Indiana, Series 88B, 3.75%,
              2/06/96.........................................      3,600
    2,000   Jasper County, Indiana, Series 88C, 3.75%,
              2/06/96.........................................      2,000
    1,100   Lehigh County, Pennsylvania, 3.85%, 1/30/96.......      1,100
    6,600   Massachusetts Health & Education Facilities
              Authority, Harvard University, Series L, 3.80%,
              2/09/96.........................................      6,600
    6,020   Montgomery, Alabama, Industrial Development Board,
              General Electric Series, 3.80%, 2/08/96.........      6,020
    4,000   Mount Vernon, Indiana, Pollution Control & Solid
              Waste Disposal Revenue Bonds, General Electric
              Project, Series 89A, 3.70%, 2/27/96.............      4,000
    4,000   Mount Vernon, Indiana, Pollution Control & Solid
              Waste Disposal Revenue Bonds, General Electric
              Project, Series 89A, 3.80%, 2/07/96.............      4,000
    4,025   North Carolina Eastern Municipal Power, 3.75%,
              2/26/96.........................................      4,025
      300   Northeastern Pennsylvania Hospital Authority,
              Series B, 3.85%, 2/07/96........................        300
    2,990   Omaha, Nebraska, Public Power District, 3.85%,
              2/07/96.........................................      2,990
    1,000   Peninsula Ports Authority, Virginia, Series 92,
              3.75%, 2/12/96..................................      1,000
    3,000   Petersburg, Indiana, Indiana Power & Light, Series
              91, 3.70%, 2/13/96..............................      3,000
    2,200   Platte River Authority, Colorado, 3.80%,
              1/22/96.........................................      2,200
    1,000   Rochester, Minnesota, Health Facilities, Mayo
              Clinic, Series B, 3.80%, 2/08/96................      1,000
    1,500   Rochester, Minnesota, Health Facilities, Mayo
              Clinic, Series C, 3.80%, 2/08/96................      1,500
    1,065   Rochester, Minnesota, Health Facilities, Mayo
              Clinic, Series E, 3.80%, 2/08/96................      1,065
    1,500   Rochester, Minnesota, Health Facilities, Mayo
              Clinic, Series F, 3.75%, 2/26/96................      1,500
    5,750   State of Louisiana, General Obligation Bond,
              3.80%, 2/21/96..................................      5,750
    8,950   Sunshine State, Florida, Government Finance
              Authority, Series 86, 3.50%, 3/08/96............      8,950
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Municipal Money Market Portfolio
 
                                      118
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE MUNICIPAL MONEY MARKET PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
   FACE                                                         AMORTIZED
  AMOUNT                                                           COST
  (000)                                                           (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
$   5,000   Sweetwater County, Wyoming, Series 88A, 3.50%,
              3/08/96.........................................  $   5,000
    6,000   Salt River, Arizona, 3.90%, 1/17/96...............      6,000
    2,000   Salt River, Arizona, 3.75%, 2/14/96...............      2,000
    3,000   State of New York, General Obligation Bond, BAN,
              Series Q, 3.75%, 2/05/96........................      3,000
    2,000   Sunshine State, Florida, Government Finance
              Authority, Series 86, 3.85%, 1/30/96............      2,000
    6,600   Texas Municipal Power Agency, 3.65%, 2/15/96......      6,600
    2,000   Texas Municipal Power Agency, 3.75%, 2/22/96......      2,000
    1,000   Trimble County, Kentucky, Louisville Gas &
              Electric Series, 3.70%, 2/13/96.................      1,000
    5,000   Trimble County, Kentucky, Louisville Gas &
              Electric Series, 3.80%, 3/07/96.................      5,000
    5,500   University of Minnesota, Series A, 3.80%,
              2/06/96.........................................      5,500
    3,000   University of Texas, Series A, 3.80%, 2/05/96.....      3,000
    2,500   Vanderbilt University, Tennessee, Series 89A,
              3.75%, 2/22/96..................................      2,500
                                                                ----------
                                                                  180,055
                                                                ----------
      TOTAL FIXED RATE INSTRUMENTS............................    198,151
                                                                ----------
        VARIABLE/FLOATING RATE INSTRUMENTS (52.5%)
          DAILY VARIABLE RATE BONDS (34.1%)
    1,500   Ascension Parish, Louisiana, Pollution Control
              Revenue Bonds, Shell Oil Project, 6.00%,
              9/01/23.........................................      1,500
    2,400   Birmingham, Alabama, Medical Clinic Board Revenue,
              University of Alabama Hospital Services Fund,
              6.10%, 12/01/26.................................      2,400
    5,500   Burke County, Georgia, Development Authority,
              Series 94, 5.50%, 7/01/24.......................      5,500
    6,300   Burke County, Georgia, Development Authority,
              6.00%, 4/01/25..................................      6,300
    6,000   California Pollution Control Financing Authority,
              Southern Edison, Series 86A, 5.40%, 2/28/08.....      6,000
    4,000   Chattanooga-Hamilton County, Tennessee, Hospital
              Authority Revenue, Erlanger Medical Center,
              6.10%, 10/01/17.................................      4,000
    4,200   Chicago, Illinois, O'Hare International Airport
              Special Facilities Revenue Bonds, American
              Airlines, Series A, 6.00%, 12/01/17.............      4,200
    4,200   Chicago, Illinois, O'Hare International Airport
              Special Facilities Revenue Bonds, American
              Airlines, Series B, 6.00%, 12/01/17.............      4,200
      700   Delaware County, Pennsylvania, Industrial
              Development Authority, Series 95, 6.00%,
              12/01/09........................................        700
<CAPTION>
   FACE                                                         AMORTIZED
  AMOUNT                                                           COST
  (000)                                                           (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
$   1,700   Delta County, Michigan, Pollution Control Revenue
              Bonds, Mead Corp., 5.90%, 12/01/23..............  $   1,700
      700   East Baton Rouge Parish, Louisiana, Pollution
              Control Revenue Bonds, Exxon Project, 5.90%,
              11/01/19........................................        700
    1,000   Hapeville, Georgia, Industrial Development
              Authority, Series 85, 6.00%, 11/01/15...........      1,000
    3,700   Harris County, Texas, Health Facilities
              Development Corp., St. Lukes Episcopal, Series
              6.00%, 2/15/16..................................      3,700
      200   Harris County, Texas, Pollution Control Revenue
              Bonds, Exxon Project, Series 84B, 6.00%,
              3/01/24.........................................        200
    5,700   Hurley, New Mexico, Pollution Control Revenue
              Bonds, 5.95%, 12/01/15..........................      5,700
    8,600   Jackson County, Mississippi, Port Facility,
              Chevron Project, Series 93, 5.95%, 6/01/23......      8,600
      900   Kansas City, Kansas, Industrial Development
              Authority, PQ Corp., 6.00%, 8/01/15.............        900
    1,900   Lake Charles, Louisiana, Harbor & Terminal
              District Port Facilities, Series 84, 5.95%,
              11/01/11........................................      1,900
    2,500   Lincoln County, Wyoming, Pollution Control Revenue
              Bonds, Exxon Project, Series 84A, 5.90%,
              11/01/14........................................      2,500
    4,400   Lincoln County, Wyoming, Pollution Control Revenue
              Bonds, Exxon Project, Series 84A, 5.95%,
              8/01/15.........................................      4,400
      900   Lincoln County, Wyoming, Pollution Control Revenue
              Bonds, Exxon Project, Series 84D, 5.90%,
              11/01/14........................................        900
    1,620   Louisiana Public Facilities Authority, Industrial
              Development, Kenner Hotel Series, 6.00%,
              12/01/15........................................      1,620
    4,500   Maricopa County, Arizona, Pollution Control
              Revenue Bonds, Series 94B, 5.95%, 5/01/29.......      4,500
    4,600   Maricopa County, Arizona, Public Services, Series
              94C, 6.00%, 5/01/29.............................      4,600
    1,000   Marshall County, West Virginia, Pollution Control
              Revenue Bonds, Mountaineer Carbon Co., 6.00%,
              12/01/20........................................      1,000
    6,700   Michigan State Strategic Fund, Consumers Power
              Series 88A, 5.95%, 4/15/18......................      6,700
    1,570   Missouri State Health & Educational Facilities
              Authority Revenue, Washington University, Series
              89A, 6.00%, 3/01/17.............................      1,570
    3,700   Monroe County, Georgia, Pollution Control Revenue
              Bonds, Georgia Power Co., Series 2, 5.50%,
              7/01/25.........................................      3,700
    3,900   New York City, New York, Cultural Resources,
              5.90%, 12/01/15.................................      3,900
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                Municipal Money Market Portfolio
 
                                      119
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE MUNICIPAL MONEY MARKET PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
   FACE                                                         AMORTIZED
  AMOUNT                                                           COST
  (000)                                                           (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
$   2,100   New York City, New York, Water Finance Authority,
              Water & Sewer System Revenue Bonds, Series 92C,
              5.90%, 6/15/22..................................  $   2,100
   18,400   New York City, New York, Water Finance Authority,
              Water & Sewer System Revenue Bonds, Series 94C,
              5.90%, 6/15/23..................................     18,400
    2,900   New York State, Energy Research and Development
              Authority, Pollution Control Revenue Bonds,
              5.95%, 12/01/25.................................      2,900
    1,000   Nueces River Authority, Texas, Pollution Control
              Revenue Bonds, Series 85, 6.10%, 12/01/99.......      1,000
    3,000   Ohio State Air Quality Development Authority
              Revenue Bonds, Series 85A, 5.50%, 12/01/15......      3,000
    1,400   Ohio State Air Quality Development Authority
              Revenue Bonds, Cincinnati Gas & Electric, Series
              B, 5.95%, 9/01/30...............................      1,400
      700   Peninsula Ports Authority, Virginia, Coal Revenue
              Bonds, 5.95%, 7/01/16...........................        700
    4,300   Pennsylvania Higher Education Authority Revenue
              Bonds, Carnegie Mellon University, Series 95B,
              6.00%, 11/01/27.................................      4,300
    3,300   Pennsylvania Higher Education Authority Revenue
              Bonds, Carnegie Mellon University, Series 95C,
              6.00%, 11/01/29.................................      3,300
    3,800   Platte County, Wyoming, Pollution Control Revenue
              Bonds, Series A, 6.00%, 7/01/14.................      3,800
    1,000   Platte County, Wyoming, Pollution Control Revenue
              Bonds, Series B, 6.00%, 7/01/14.................      1,000
    2,000   Port of Saint Helens, Oregon, Pollution Control
              Revenue Bonds, Portland General Electric Co.,
              Series A, 5.95%, 4/01/10........................      2,000
    1,600   Port of Saint Helens, Oregon, Pollution Control
              Revenue Bonds, Portland General Electric Co.,
              Series B, 5.95%, 6/01/10........................      1,600
    1,400   Saint Charles Parish, Louisiana, Pollution Control
              Revenue Bonds, Shell Oil Project, 5.95%,
              10/01/22........................................      1,400
    5,000   Salt Lake County, Utah, Pollution Control Revenue
              Bonds, British Petroleum Co., 5.95%, 2/01/08....      5,000
    2,700   Salt Lake County, Utah, Pollution Control Revenue
              Bonds, SVC Station Holdings, 6.00%, 8/01/07.....      2,700
    4,900   Southwest, Texas, Higher Education Authority
              Revenue Bonds, Southern Methodist University,
              Series 85, 5.95%, 7/01/15.......................      4,900
                                                                ----------
                                                                  154,090
                                                                ----------
          WEEKLY VARIABLE RATE BONDS (18.4%)
    1,000   Albuquerque, New Mexico, Revenue Bond, Series A,
              5.15%, 7/01/22..................................      1,000
<CAPTION>
   FACE                                                         AMORTIZED
  AMOUNT                                                           COST
  (000)                                                           (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
$   1,000   Beaver County, Pennsylvania, Industrial
              Development Authority, Duquesne Light Series,
              4.95%, 8/01/09..................................  $   1,000
    1,000   Beaver County, Pennsylvania, Industrial
              Development Authority, Duquesne Light Series,
              4.95%, 8/01/20..................................      1,000
    1,000   Brunswick & Glynn County, Georgia, Development
              Authority, Series 85, 5.25%, 12/01/15...........      1,000
    7,000   Burke County, Georgia, Development Authority,
              Oglethorpe, Series 93A, 5.15%, 1/01/16..........      7,000
    5,800   Charlotte, North Carolina, Airport, Series 93A,
              5.15%, 7/01/16..................................      5,800
    1,000   City of Baltimore, Maryland, Pollution Control
              Revenue Bonds, General Motors Corp., 5.10%,
              2/01/00.........................................      1,000
    2,500   City of Columbia, Missouri, Special Revenue Bonds,
              Series 88A, 5.15%, 6/01/08......................      2,500
    1,500   City of Columbia, Missouri, Water & Electric
              Revenue Bonds, Series 85B, 5.15%, 12/01/15......      1,500
      300   City of Forsyth, Montana, Pollution Control
              Revenue Bonds, Series B, 5.00%, 6/01/13.........        300
      700   City of Forsyth, Montana, Pollution Control
              Revenue Bonds, Series D, 4.90%, 6/01/13.........        700
    2,600   City of Midlothian, Texas, Industrial Development
              Corp., Pollution Control Revenue Bonds, Box-Crow
              Cement Co., 5.80%, 12/01/09.....................      2,600
    1,000   City of Minnetonka, Minnesota, Multifamily, Cliffs
              Ridgedale, 5.20%, 9/15/25.......................      1,000
    1,700   City of San Antonio, Texas, Higher Education
              Authority, Trinity University, 5.20%, 4/01/04...      1,700
    7,800   Clark County, Nevada, Airport Revenue Bonds,
              Series 93A, 5.15%, 7/01/12......................      7,800
    2,700   Clark County, Nevada, Airport Revenue Bonds,
              Series 95-A1, 5.05%, 7/01/25....................      2,700
    4,000   Clark County, Nevada, Industrial Development Corp,
              Nevada Power Co., Series C, 5.05%, 10/01/30.....      4,000
      280   Clear Creek County, Colorado, Revenue Bonds,
              Colorado Finance Pool Program, 5.15%, 6/01/98...        280
      600   Colorado Student Obligation Bond Authority,
              Student Loan Revenue, Series 91C1, 5.05%,
              8/01/00.........................................        600
    7,200   Dade County, Florida, Water & Sewer Revenue Bonds,
              4.90%, 10/05/22.................................      7,200
    1,200   Delaware County, Pennsylvania, Industrial
              Development Authority, Scott Paper Series D,
              5.00%, 12/01/18.................................      1,200
</TABLE>
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
Municipal Money Market Portfolio
 
                                      120
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
STATEMENT OF NET ASSETS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
THE MUNICIPAL MONEY MARKET PORTFOLIO (CONT.)
- --------------------------------------------------------------------------------
<TABLE>
<CAPTION>
   FACE                                                         AMORTIZED
  AMOUNT                                                           COST
  (000)                                                           (000)
- ------------------------------------------------------------
<C>         <S>                                                 <C>
$     500   Delaware County, Pennsylvania, Industrial
              Development Authority, Scott Paper Series E,
              5.00%, 12/01/18.................................  $     500
    3,000   Foothill/Eastern California Toll Road Revenue,
              Series 95C, 4.80%, 1/02/35......................      3,000
    5,000   Harris County, Texas, Series 94G, 5.10%,
              8/01/20.........................................      5,000
    5,000   Harris County, Texas, Series 94H, 5.10%,
              8/01/20.........................................      5,000
      300   Illinois Development Finance Authority, A.E.
              Staley Manufacturing Series 85, 5.05%,
              12/01/05........................................        300
    1,000   Lehigh County, Pennsylvania, Allegheny Electric
              Cooperative, 5.25%, 12/01/15....................      1,000
    1,500   Louisiana Public Facilities Authority, Hospital
              Revenue, Series 85, 6.40%, 12/01/00.............      1,500
    1,000   Massachusetts Health & Education Facilities
              Authority, Series G-1, 4.75%, 1/01/19...........      1,000
    3,900   Nueces County, Texas, Health Facilities, Driscoll
              Childrens' Foundation, 5.20%, 7/01/15...........      3,900
    1,500   Person County, North Carolina, Carolina Power &
              Light, 5.20%, 11/01/19..........................      1,500
      235   Pinellas County, Florida, Health Facilities,
              Bayfront Medical Center, Series 89, 4.90%,
              6/01/98.........................................        235
      450   Polk County, Iowa, Hospital Equipment &
              Improvement Authority, 5.15%, 12/01/05 .                450
      800   Port Development Corporation Marine Terminal,
              Texas, Series 89, 5.05%, 1/15/14................        800
    1,500   Port of Corpus Christi, Texas, Marine Terminal,
              R.J. Reynolds Metals Series, 5.25%, 9/01/14.....      1,500
      600   Putnam County, Florida, Development Authority,
              Seminole Electric Series 84 H1, 4.65%,
              3/15/14.........................................        600
    1,000   Rapides Parish, Louisiana, Central Louisiana
              Electric Series, 5.05%, 7/01/18 .                     1,000
      700   Sheboygan, Wisconsin, Wisconsin Power & Light
              Series, 5.25%, 8/01/14..........................        700
    1,100   University of North Carolina, Chapel Hill Fund
              Inc., Certificates of Participation, 5.10%,
              10/01/09........................................      1,100
    2,000   Washington Public Power, Series 93-1A3, 4.95%,
              7/01/17.........................................      2,000
                                                                ----------
                                                                   82,965
                                                                ----------
  TOTAL VARIABLE/FLOATING RATE INSTRUMENTS....................    237,055
                                                                ----------
TOTAL TAX-EXEMPT INSTRUMENTS (Cost $435,206)..................    435,206
                                                                ----------
TAXABLE INSTRUMENT (3.3%)
  U.S. GOVERNMENT & AGENCY OBLIGATION (3.3%)
   14,820   Federal Home Loan Bank Discount Note, 5.57%,
              1/05/96 (Cost $14,811)..........................     14,811
                                                                ----------
TOTAL INVESTMENTS (99.7%) (Cost $450,017).....................    450,017
                                                                ----------
</TABLE>
 
<TABLE>
<CAPTION>
                                                                  AMOUNT
                                                                  (000)
<S>                                                 <C>         <C>
- ------------------------------------------------------------
OTHER ASSETS (0.6%)
  Interest Receivable.............................  $    2,563
  Other...........................................          29  $    2,592
                                                    ----------
LIABILITIES (-0.3%)
  Dividends Payable...............................        (607)
  Investment Advisory Fees Payable................        (338)
  Administrative Fees Payable.....................         (63)
  Custodian Fees Payable..........................         (12)
  Payable to Custodian............................         (10)
  Director's Fees & Expenses......................          (2)
  Other Liabilities...............................         (58)     (1,090)
                                                    ----------  ----------
NET ASSETS (100%).............................................  $  451,519
                                                                ----------
                                                                ----------
NET ASSET VALUE, OFFERING AND
  REDEMPTION PRICE PER SHARE
  Applicable to 451,502,422 outstanding $.001 par value shares
  (authorized 4,000,000,000 shares)...........................       $1.00
                                                                ----------
                                                                ----------
</TABLE>
 
- ------------------------------------------------------------
 
<TABLE>
<S>        <C>
BAN        -- Bond Anticipation Note
TRANS      -- Tax & Revenue Anticipation Notes
</TABLE>
 
Variable/Floating Rate Instruments. The interest rate changes on these
instruments are based on changes in a designated base rate. These instruments
are payable on demand and are secured by a letter of credit or other support
agreements.
 
Maturity dates disclosed for Variable/Floating Rate Instruments are the ultimate
maturity dates. The effective maturity dates for such securities are the next
interest reset dates which are seven days or less.
 
Interest rates disclosed for U.S. Government & Agency Obligations represent
effective yields at December 31, 1995.
 
At December 31, 1995, approximately 12% of the net assets were invested in Texas
municipal securities. Economic changes affecting the state and certain of it's
public bodies and municipalities may affect the ability of issuers to pay the
required principal and interest payments of the municipal securities.
 
The accompanying notes are an integral part of the financial statements. (Pages
                                    150-156)
 
- --------------------------------------------------------------------------------
                                                Municipal Money Market Portfolio
 
                                      121
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
 
STATEMENT OF OPERATIONS
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                      ACTIVE                    EMERGING
                                                     COUNTRY          ASIAN      MARKETS        EUROPEAN
                                                  ALLOCATION         EQUITY    PORTFOLIO          EQUITY  GLOBAL EQUITY
                                                   PORTFOLIO      PORTFOLIO   YEAR ENDED  PORTFOLIO YEAR      PORTFOLIO
                                                  YEAR ENDED     YEAR ENDED     DECEMBER  ENDED DECEMBER     YEAR ENDED
                                                DECEMBER 31,   DECEMBER 31,          31,             31,   DECEMBER 31,
                                                        1995           1995         1995            1995           1995
                                                       (000)          (000)        (000)           (000)          (000)
- -----------------------------------------------------------------------------------------------------------------------
<S>                                            <C>            <C>            <C>          <C>             <C>
INVESTMENT INCOME:
  Dividends                                        $   3,730      $   5,477    $  19,196       $   1,146      $   1,896
  Interest                                               179            711        4,215             245             48
  Less: Foreign Taxes Withheld                          (519)          (487)      (1,993)           (158)          (168)
                                               -------------  -------------  -----------          ------  -------------
    Total Income                                       3,390          5,701       21,418           1,233          1,776
                                               -------------  -------------  -----------          ------  -------------
EXPENSES:
  Investment Advisory Fees:
    Basic Fees -- Adviser                              1,068          2,301       11,563             416            653
    Less: Fees Waived                                   (618)          (522)          --            (130)          (109)
                                               -------------  -------------  -----------          ------  -------------
  Investment Advisory Fees -- Net                        450          1,779       11,563             286            544
  Administrative Fees                                    322            458        1,458             100            141
  Sub-Administrative Fees                                  2             --          173              --             --
  Custodian Fees                                         403            474        2,073              51             44
  Filing and Registration Fees                            18             23           45              24             16
  Insurance                                               15             21           69               2              4
  Directors' Fees and Expenses                             7             10           47               3              4
  Legal Fees                                               8             13           39               3              5
  Audit Fees                                              42             46          113              38             42
  Shareholder Reports                                     37             25           81               9             11
  Foreign Tax Expense                                     --             28          202              --             --
  Other Expenses                                          12             28           42               3              5
                                               -------------  -------------  -----------          ------  -------------
    Total Expenses                                     1,316          2,905       15,905             519            816
                                               -------------  -------------  -----------          ------  -------------
NET INVESTMENT INCOME                                  2,074          2,796        5,513             714            960
                                               -------------  -------------  -----------          ------  -------------
NET REALIZED GAIN (LOSS):
  Investments sold                                     5,468         12,299      (33,253)*            604         5,893
  Foreign Currency Transactions                       (6,591)           160         (981)             39            (86)
                                               -------------  -------------  -----------          ------  -------------
    Total Net Realized Gain (Loss)                    (1,123)        12,459      (34,234)            643          5,807
                                               -------------  -------------  -----------          ------  -------------
CHANGE IN UNREALIZED APPRECIATION
  (DEPRECIATION):
  Investments                                          5,557          7,840     (101,142)          3,003          7,313
  Foreign Currency Translations                       10,118             12        4,125              39           (118)
                                               -------------  -------------  -----------          ------  -------------
    Total Net Change in Unrealized
     Appreciation (Depreciation)                      15,675          7,852      (97,017)          3,042          7,195
                                               -------------  -------------  -----------          ------  -------------
TOTAL NET REALIZED GAIN (LOSS) AND CHANGE IN
  UNREALIZED APPRECIATION (DEPRECIATION)              14,552         20,311     (131,251)          3,685         13,002
                                               -------------  -------------  -----------          ------  -------------
  Net Increase (Decrease) in Net Assets
    Resulting from Operations                      $  16,626      $  23,107    $(125,738)      $   4,399      $  13,962
                                               -------------  -------------  -----------          ------  -------------
                                               -------------  -------------  -----------          ------  -------------
</TABLE>
 
- ---------------
*Net of foreign tax of $650,000 on net realized gains.
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
 
                                      122
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
 
STATEMENT OF OPERATIONS
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                INTERNATIONAL                                    LATIN AMERICAN
                                                                       EQUITY   INTERNATIONAL        JAPANESE         PORTFOLIO
                                                GOLD PORTFOLIO      PORTFOLIO       SMALL CAP          EQUITY       JANUARY 18,
                                                    YEAR ENDED     YEAR ENDED  PORTFOLIO YEAR  PORTFOLIO YEAR          1995* TO
                                                  DECEMBER 31,   DECEMBER 31,  ENDED DECEMBER  ENDED DECEMBER      DECEMBER 31,
                                                          1995           1995        31, 1995        31, 1995              1995
                                                         (000)          (000)           (000)           (000)             (000)
- ------------------------------------------------------------------------------------------------------------------------------
<S>                                            <C>              <C>            <C>             <C>             <C>
INVESTMENT INCOME:
  Dividends                                          $      84      $  34,103       $   5,511       $     524         $     263
  Interest                                                  92          4,293             549             229               108
  Less: Foreign Taxes Withheld                              (6)        (4,270)           (630)            (78)              (19)
                                                        ------  -------------         -------         -------             -----
    Total Income                                           170         34,126           5,430             675               352
                                                        ------  -------------         -------         -------             -----
EXPENSES:
  Investment Advisory Fees:
    Basic Fees -- Adviser                                  109         11,452           1,796             469               146
    Basic Fees -- Sub Adviser                               73             --              --              --                --
    Less: Fees Waived -- Adviser                           (55)          (424)           (181)           (118)             (146)
         Fees Waived -- Sub Adviser                        (37)            --              --              --                --
                                                        ------  -------------         -------         -------             -----
  Investment Advisory Fees -- Net                           90         11,028           1,615             351                --
  Administrative Fees                                       35          2,252             309             101                27
  Sub-Administrative Fees                                   --             --              --              --                 9
  Custodian Fees                                            19            545             126              38               111
  Filing and Registration Fees                              18             47              24              35                17
  Insurance                                                  1            100              11               4                --
  Directors' Fees and Expenses                               3             43               7               3                 2
  Legal Fees                                                 2             57               9               3                 5
  Audit Fees                                                37             61              46              37                39
  Shareholder Reports                                       19             99              17               9                11
  Foreign Tax Expense                                       --             --              --              --                45
  Other Expenses                                             3             81              10               4                 4
                                                        ------  -------------         -------         -------             -----
    Total Expenses                                         227         14,313           2,174             585               270
                                                        ------  -------------         -------         -------             -----
NET INVESTMENT INCOME (LOSS)                               (57)        19,813           3,256              90                82
                                                        ------  -------------         -------         -------             -----
NET REALIZED GAIN (LOSS):
  Investments Sold                                         880        108,572           7,974          (2,999)             (530)
  Foreign Currency Transactions                             (4)       (20,102)           (297)             --               (13)
                                                        ------  -------------         -------         -------             -----
    Total Net Realized Gain (Loss)                         876         88,470           7,677          (2,999)             (543)
                                                        ------  -------------         -------         -------             -----
CHANGE IN UNREALIZED APPRECIATION
  (DEPRECIATION):
  Investments Sold                                       2,423         44,604          (6,040)          2,624               208
  Foreign Currency Translations                             --          6,374            (771)          3,310                --
                                                        ------  -------------         -------         -------             -----
    Total Net Change in Unrealized
     Appreciation (Depreciation)                         2,423         50,978          (6,811)          5,934               208
                                                        ------  -------------         -------         -------             -----
TOTAL NET REALIZED GAIN (LOSS) AND CHANGE IN
  UNREALIZED
  APPRECIATION (DEPRECIATION)                            3,299        139,448             866           2,935              (335)
                                                        ------  -------------         -------         -------             -----
  Net Increase (Decrease) in Net Assets
    Resulting from Operations                        $   3,242      $ 159,261       $   4,122       $   3,025         $    (253)
                                                        ------  -------------         -------         -------             -----
                                                        ------  -------------         -------         -------             -----
</TABLE>
 
- ---------------
*Commencement of operations.
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
 
                                      123
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
 
STATEMENT OF OPERATIONS
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                 AGGRESSIVE                                 SMALL CAP     U.S. REAL
                                     EQUITY      EMERGING        EQUITY         VALUE        ESTATE         VALUE
                                  PORTFOLIO        GROWTH        GROWTH        EQUITY     PORTFOLIO        EQUITY      BALANCED
                                   MARCH 8,     PORTFOLIO     PORTFOLIO     PORTFOLIO      FEBRUARY     PORTFOLIO     PORTFOLIO
                                   1995* TO    YEAR ENDED    YEAR ENDED    YEAR ENDED     24, 1995*    YEAR ENDED    YEAR ENDED
                                   DECEMBER      DECEMBER      DECEMBER      DECEMBER   TO DECEMBER      DECEMBER      DECEMBER
                                   31, 1995      31, 1995      31, 1995      31, 1995      31, 1995      31, 1995      31, 1995
                                      (000)         (000)         (000)         (000)         (000)         (000)         (000)
- ------------------------------------------------------------------------------------------------------------------------------
<S>                             <C>           <C>           <C>           <C>           <C>           <C>           <C>
INVESTMENT INCOME:
  Dividends                     $       338   $       203   $     2,580   $     1,575   $     1,796   $     3,986   $       374
  Interest                               88           445           694           118           103           245           642
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
    Total Income                        426           648         3,274         1,693         1,899         4,231         1,016
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
EXPENSES:
  Investment Advisory Fees:
    Basic Fees -- Adviser               128         1,325           830           400           299           570           106
    Less: Fees Waived                   (96)          (18)         (105)          (97)         (129)          (85)          (68)
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
  Investment Advisory
    Fees -- Net                          32         1,307           725           303           170           485            38
  Administrative Fees                    28           214           223            82            61           183            42
  Custodian Fees                         19            29            46            19            36            30            12
  Filing and Registration Fees           18            22            23            14            29            27            13
  Insurance                               1             9             8             3             1             7             2
  Directors' Fees and Expenses            2             6             6             4             2             5             3
  Legal Fees                             24             6             6             3            25             5             2
  Audit Fees                             22            27            32            25            22            27            25
  Shareholder Reports                    12            28            28            13            25            21             8
  Other Expenses                          2             9             8             4             2             7             3
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
    Total Expenses                      160         1,657         1,105           470           373           797           148
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
NET INVESTMENT INCOME (LOSS)            266        (1,009)        2,169         1,223         1,526         3,434           868
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
NET REALIZED GAIN (LOSS):
  Investments Sold                    4,082        11,225        32,477         1,546         3,495        10,276         1,158
  Written Options                       (22)           --            --            --            --            --            --
  Securities Sold Short                 (19)           --            --            --            --            --            --
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
    Total Net Realized Gain           4,041        11,225        32,477         1,546         3,495        10,276         1,158
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
CHANGE IN UNREALIZED
  APPRECIATION (DEPRECIATION)         1,860        27,942        15,685         5,880         3,896        17,116         2,413
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
TOTAL NET REALIZED GAIN AND
  CHANGE IN UNREALIZED
  APPRECIATION (DEPRECIATION)         5,901        39,167        48,162         7,426         7,391        27,392         3,571
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
  Net Increase in Net Assets
    Resulting from Operations   $     6,167   $    38,158   $    50,331   $     8,649   $     8,917   $    30,826   $     4,439
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
</TABLE>
 
- ---------------
*Commencement of operations.
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
 
                                      124
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
 
STATEMENT OF OPERATIONS
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                   EMERGING                      GLOBAL                   MUNICIPAL                   MUNICIPAL
                                    MARKETS         FIXED         FIXED                        BOND         MONEY         MONEY
                                       DEBT        INCOME        INCOME    HIGH YIELD     PORTFOLIO        MARKET        MARKET
                                  PORTFOLIO     PORTFOLIO     PORTFOLIO     PORTFOLIO   JANUARY 18,     PORTFOLIO     PORTFOLIO
                                 YEAR ENDED    YEAR ENDED    YEAR ENDED    YEAR ENDED      1995* TO    YEAR ENDED    YEAR ENDED
                                   DECEMBER      DECEMBER      DECEMBER      DECEMBER      DECEMBER      DECEMBER      DECEMBER
                                   31, 1995      31, 1995      31, 1995      31, 1995      31, 1995      31, 1995      31, 1995
                                      (000)         (000)         (000)         (000)         (000)         (000)         (000)
- ------------------------------------------------------------------------------------------------------------------------------
<S>                             <C>           <C>           <C>           <C>           <C>           <C>           <C>
INVESTMENT INCOME:
  Dividends                     $        --   $        --   $        --   $        53   $        --   $        --   $        --
  Interest                           28,018        13,011         6,987         7,927         2,154        48,910        15,686
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
    Total Income                     28,018        13,011         6,987         7,980         2,154        48,910        15,686
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
EXPENSES:
  Investment Advisory Fees:
    Basic Fees -- Adviser             1,702           624           383           335           149         2,500         1,210
    Less: Fees Waived                    --          (247)         (204)          (55)         (119)           --            --
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
  Investment Advisory
    Fees -- Net                       1,702           377           179           280            30         2,500         1,210
  Administrative Fees                   275           288           157           118            72         1,307           635
  Custodian Fees                        204            27            46            20             9           119            72
  Filing and Registration Fees           18            17            19            18            23            58            54
  Insurance                              10            14             9             7             1            67            31
  Interest Expense                      616            --            --            --            --            --            --
  Directors' Fees and Expenses           25             7             5             4             3            29            14
  Legal Fees                              9             8             5             4            14            25            13
  Audit Fees                             72            26            35            32            22            23            27
  Shareholder Reports                    23            18            15            13            14            57            26
  Other Expenses                         44            21             9             7             3            68            25
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
    Total Expenses                    2,998           803           479           503           191         4,253         2,107
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
NET INVESTMENT INCOME                25,020        12,208         6,508         7,477         1,963        44,657        13,579
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
NET REALIZED GAIN (LOSS):
  Investments Sold                    9,470         5,823         1,542        (3,145)          193            79            (1)
  Foreign Currency
    Transactions                     (2,072)           98        (1,527)           --            --            --            --
  Securities Sold Short               1,116            --            --            --            --            --            --
  Written Options                       673            --            --            --            --            --            --
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
    Total Net Realized Gain
      (Loss)                          9,187         5,921            15        (3,145)          193            79            (1)
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
CHANGE IN UNREALIZED
  APPRECIATION (DEPRECIATION):
  Investments Sold                   15,093        12,945         9,810         9,886         1,635            --            --
  Foreign Currency
    Translations                        197           180           381            --            --            --            --
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
    Total Net Change in
      Unrealized
      Appreciation
      (Depreciation)                 15,290        13,125        10,191         9,886         1,635            --            --
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
TOTAL NET REALIZED GAIN (LOSS)
  AND CHANGE IN UNREALIZED
  APPRECIATION (DEPRECIATION)        24,477        19,046        10,206         6,741         1,828            79            (1)
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
  Net Increase in Net Assets
    Resulting from Operations   $    49,497   $    31,254   $    16,714   $    14,218   $     3,791   $    44,736   $    13,578
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
</TABLE>
 
- ---------------
*Commencement of operations.
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
 
                                      125
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
 
STATEMENT OF CHANGES IN NET ASSETS
- --------------------------------------------------------------------------------
 
THE ACTIVE COUNTRY ALLOCATION PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                  YEAR ENDED      YEAR ENDED
                                                                DECEMBER 31,    DECEMBER 31,
                                                                        1994            1995
                                                                       (000)           (000)
- --------------------------------------------------------------------------------------------
<S>                                                           <C>             <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Income                                            $   2,652       $   2,074
  Net Realized Gain (Loss)                                             8,147          (1,123)
  Change in Unrealized Appreciation (Depreciation)                   (12,455)         15,675
                                                              --------------  --------------
  Net Increase (Decrease) in Net Assets Resulting from
   Operations                                                         (1,656)         16,626
                                                              --------------  --------------
DISTRIBUTIONS:
  Net Investment Income                                               (1,773)         (3,492)
  In Excess of Net Investment Income                                       -          (1,308)
  Net Realized Gain                                                   (4,419)        (12,502)
                                                              --------------  --------------
  Total Distributions                                                 (6,192)        (17,302)
                                                              --------------  --------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                         169,994          88,081
  Distributions Reinvested                                             5,395          15,283
  Redeemed                                                          (135,418)       (115,002)
                                                              --------------  --------------
  Net Increase (Decrease) from Capital Share Transactions             39,971         (11,638)
                                                              --------------  --------------
  Total Increase (Decrease) in Net Assets                             32,123         (12,314)
NET ASSETS:
  Beginning of Period                                                150,854         182,977
                                                              --------------  --------------
  End of Period (2)                                                $ 182,977       $ 170,663
                                                              --------------  --------------
                                                              --------------  --------------
<FN>
- --------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                   14,259           7,883
  Shares Issued on Distributions Reinvested                              458           1,346
  Shares Redeemed                                                    (11,357)        (10,268)
                                                              --------------  --------------
  Net Increase (Decrease) in Capital Shares Outstanding                3,360          (1,039)
                                                              --------------  --------------
                                                              --------------  --------------
(2) Net Assets were comprised of:
  Paid in Capital                                             $      168,882  $      157,244
  Undistributed (Distributions in Excess of) Net Investment
   Income                                                              1,418          (7,782)
  Accumulated Net Realized Gain                                        7,989             838
  Unrealized Appreciation (Net of accrual for foreign tax of
   $4 on unrealized appreciation on investments at December
   31, 1995)                                                           4,688          20,363
                                                              --------------  --------------
                                                              $      182,977  $      170,663
                                                              --------------  --------------
                                                              --------------  --------------
</TABLE>
 
- --------------------------------------------------------------------------------
THE ASIAN EQUITY PORTFOLIO
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                  YEAR ENDED      YEAR ENDED
                                                                DECEMBER 31,    DECEMBER 31,
                                                                        1994            1995
                                                                       (000)           (000)
- --------------------------------------------------------------------------------------------
<S>                                                           <C>             <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Income                                            $   1,397       $   2,796
  Net Realized Gain                                                   32,848          12,459
  Change in Unrealized Appreciation (Depreciation)                   (80,975)          7,852
                                                              --------------  --------------
  Net Increase (Decrease) in Net Assets Resulting from
   Operations                                                        (46,730)         23,107
                                                              --------------  --------------
DISTRIBUTIONS:
  Net Investment Income                                                 (972)         (4,866)
  In Excess of Net Investment Income                                      --              (3)
  Net Realized Gain                                                   (5,840)        (40,469)
                                                              --------------  --------------
  Total Distributions                                                 (6,812)        (45,338)
                                                              --------------  --------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                         213,200         472,587
  Distributions Reinvested                                             6,036          41,003
  Redeemed                                                          (175,924)       (453,381)
                                                              --------------  --------------
  Net Increase from Capital Share Transactions                        43,312          60,209
                                                              --------------  --------------
  Total Increase (Decrease) in Net Assets                            (10,230)         37,978
NET ASSETS:
  Beginning of Period                                                287,136         276,906
                                                              --------------  --------------
  End of Period (2)                                                $ 276,906       $ 314,884
                                                              --------------  --------------
                                                              --------------  --------------
<FN>
- --------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                    9,345          24,613
  Shares Issued on Distributions Reinvested                              233           2,138
  Shares Redeemed                                                     (7,685)        (23,439)
                                                              --------------  --------------
  Net Increase in Capital Shares Outstanding                           1,893           3,312
                                                              --------------  --------------
                                                              --------------  --------------
(2) Net Assets were Comprised of:
  Paid in Capital                                             $      207,594  $      268,221
  Undistributed (Distributions in Excess of) Net Investment
   Income                                                              1,886              (3)
  Accumulated Net Realized Gain                                       32,350           3,738
  Unrealized Appreciation                                             35,076          42,928
                                                              --------------  --------------
                                                              $      276,906  $      314,884
                                                              --------------  --------------
                                                              --------------  --------------
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
 
                                      126
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
 
STATEMENT OF CHANGES IN NET ASSETS
- --------------------------------------------------------------------------------
 
THE EMERGING MARKETS PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                  YEAR ENDED      YEAR ENDED
                                                                DECEMBER 31,    DECEMBER 31,
                                                                        1994            1995
                                                                       (000)           (000)
- --------------------------------------------------------------------------------------------
<S>                                                           <C>             <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Income (Loss)                                     $  (2,302)      $   5,513
  Net Realized Gain (Loss)                                            66,824         (34,234)
  Change in Unrealized Appreciation (Depreciation)                  (168,042)        (97,017)
                                                              --------------  --------------
  Net Decrease in Net Assets Resulting from Operations              (103,520)       (125,738)
                                                              --------------  --------------
DISTRIBUTIONS:
  Net Investment Income                                                   --          (3,978)
  Net Realized Gain                                                  (37,393)        (66,711)
                                                              --------------  --------------
  Total Distributions                                                (37,393)        (70,689)
                                                              --------------  --------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                         579,390         379,789
  Distributions Reinvested                                            35,730          67,401
  Redeemed                                                          (279,921)       (303,810)
                                                              --------------  --------------
  Net Increase from Capital Share Transactions                       335,199         143,380
                                                              --------------  --------------
  Total Increase (Decrease) in Net Assets                            194,286         (53,047)
NET ASSETS:
  Beginning of Period                                                735,352         929,638
                                                              --------------  --------------
  End of Period (2)                                                $ 929,638       $ 876,591
                                                              --------------  --------------
                                                              --------------  --------------
<FN>
- --------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                   32,685          27,709
  Shares Issued on Distributions Reinvested                            1,974           4,586
  Shares Redeemed                                                    (16,342)        (22,595)
                                                              --------------  --------------
  Net Increase in Capital Shares Outstanding                          18,317           9,700
                                                              --------------  --------------
                                                              --------------  --------------
(2) Net Assets were comprised of:
  Paid in Capital                                             $      818,267  $      962,160
  Accumulated Net Investment Loss/Undistributed Net
   Investment Income                                                    (785)            167
  Accumulated Net Realized Gain (Loss)                                65,253         (35,622)
  Unrealized Appreciation (Depreciation) (Net of accrual for
   India tax of $4,779 and $308, respectively on unrealized
   appreciation on investments.)                                      46,903         (50,114)
                                                              --------------  --------------
                                                              $      929,638  $      876,591
                                                              --------------  --------------
                                                              --------------  --------------
</TABLE>
 
- --------------------------------------------------------------------------------
THE EUROPEAN EQUITY PORTFOLIO
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                  YEAR ENDED      YEAR ENDED
                                                                DECEMBER 31,    DECEMBER 31,
                                                                        1994            1995
                                                                       (000)           (000)
- --------------------------------------------------------------------------------------------
<S>                                                           <C>             <C>
INCREASE (DECREASE) IN NET ASSSETS
OPERATIONS:
  Net Investment Income                                            $     159       $     714
  Net Realized Gain                                                    2,606             643
  Change in Unrealized Appreciation (Depreciation)                    (1,886)          3,042
                                                              --------------  --------------
  Net Increase in Net Assets Resulting from Operations                   879           4,399
                                                              --------------  --------------
DISTRIBUTIONS:
  Net Investment Income                                                  (87)           (738)
  Net Realized Gain                                                     (251)         (3,017)
                                                              --------------  --------------
  Total Distributions                                                   (338)         (3,755)
                                                              --------------  --------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                          39,425          56,209
  Distributions Reinvested                                               337           3,468
  Redeemed                                                           (25,350)        (18,372)
                                                              --------------  --------------
  Net Increase from Capital Share Transactions                        14,412          41,305
                                                              --------------  --------------
  Total Increase in Net Assets                                        14,953          41,949
NET ASSETS:
  Beginning of Period                                                 12,681          27,634
                                                              --------------  --------------
  End of Period (2)                                                $  27,634       $  69,583
                                                              --------------  --------------
                                                              --------------  --------------
<FN>
- --------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                    2,791           4,104
  Shares Issued on Distributions Reinvested                               27             264
  Shares Redeemed                                                     (1,818)         (1,350)
                                                              --------------  --------------
  Net Increase in Capital Shares Outstanding                           1,000           3,018
                                                              --------------  --------------
                                                              --------------  --------------
(2) Net Assets were comprised of:
  Paid in Capital                                             $       25,071  $       66,433
  Undistributed Net Investment Income                                     31              24
  Accumulated Net Realized Gain                                        2,731             283
  Unrealized Appreciation (Depreciation)                                (199)          2,843
                                                              --------------  --------------
                                                              $       27,634  $       69,583
                                                              --------------  --------------
                                                              --------------  --------------
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
 
                                      127
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
 
STATEMENT OF CHANGES IN NET ASSETS
- --------------------------------------------------------------------------------
 
THE GLOBAL EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                      YEAR ENDED      YEAR ENDED
                                                                    DECEMBER 31,    DECEMBER 31,
                                                                            1994            1995
                                                                           (000)           (000)
- ------------------------------------------------------------------------------------------------
<S>                                                               <C>             <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Income                                                $     450       $     960
  Net Realized Gain                                                        1,493           5,807
  Change in Unrealized Appreciation (Depreciation)                        (1,816)          7,195
                                                                  --------------  --------------
  Net Increase in Net Assets Resulting from Operations                       127          13,962
                                                                  --------------  --------------
DISTRIBUTIONS:
  Net Investment Income                                                     (170)         (1,202)
  Net Realized Gain                                                       (1,756)         (7,032)
                                                                  --------------  --------------
  Total Distributions                                                     (1,926)         (8,234)
                                                                  --------------  --------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                              72,166          30,429
  Distributions Reinvested                                                 1,926           8,198
  Redeemed                                                               (13,276)        (31,615)
                                                                  --------------  --------------
  Net Increase from Capital Share Transactions                            60,816           7,012
                                                                  --------------  --------------
  Total Increase in Net Assets                                            59,017          12,740
NET ASSETS:
  Beginning of Period                                                     19,918          78,935
                                                                  --------------  --------------
  End of Period (2)                                                    $  78,935       $  91,675
                                                                  --------------  --------------
                                                                  --------------  --------------
<FN>
- ------------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                        5,281           2,175
  Shares Issued on Distributions Reinvested                                  154             583
  Shares Redeemed                                                           (982)         (2,239)
                                                                  --------------  --------------
  Net Increase in Capital Shares Outstanding                               4,453             519
                                                                  --------------  --------------
                                                                  --------------  --------------
(2) Net Assets were comprised of:
  Paid in Capital                                                      $  75,435       $  82,447
  Undistributed Net Investment Income                                        373              --
  Accumulated Net Realized Gain                                            1,568             474
  Unrealized Appreciation                                                  1,559           8,754
                                                                  --------------  --------------
                                                                       $  78,935       $  91,675
                                                                  --------------  --------------
                                                                  --------------  --------------
</TABLE>
 
- --------------------------------------------------------------------------------
THE GOLD PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                       PERIOD FROM
                                                                 FEBRUARY 1, 1994*      YEAR ENDED
                                                                   TO DECEMBER 31,    DECEMBER 31,
                                                                              1994            1995
                                                                             (000)           (000)
- --------------------------------------------------------------------------------------------------
<S>                                                              <C>                <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Income (Loss)                                           $      77       $     (57)
  Net Realized Gain                                                            971             876
  Change in Unrealized Appreciation (Depreciation)                          (2,809)          2,423
                                                                           -------  --------------
  Net Increase (Decrease) in Net Assets Resulting from
   Operations                                                               (1,761)          3,242
                                                                           -------  --------------
DISTRIBUTIONS:
  Net Investment Income                                                        (38)            (37)
  Net Realized Gain                                                             --          (2,066)
                                                                           -------  --------------
  Total Distributions                                                          (38)         (2,103)
                                                                           -------  --------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                                40,892          21,820
  Distributions Reinvested                                                      32           1,913
  Redeemed                                                                  (8,882)        (47,706)
                                                                           -------  --------------
  Net Increase (Decrease) from Capital Share Transactions                   32,042         (23,973)
                                                                           -------  --------------
  Total Increase (Decrease) in Net Assets                                   30,243         (22,834)
NET ASSETS:
  Beginning of Period                                                           --          30,243
                                                                           -------  --------------
  End of Period (2)                                                      $  30,243       $   7,409
                                                                           -------  --------------
                                                                           -------  --------------
<FN>
- --------------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                          4,264           2,403
  Shares Issued on Distributions Reinvested                                      3             222
  Shares Redeemed                                                             (954)         (5,071)
                                                                           -------  --------------
  Net Increase (Decrease) in Capital Shares Outstanding                      3,313          (2,446)
                                                                           -------  --------------
                                                                           -------  --------------
(2) Net Assets were comprised of:
  Paid in Capital                                                        $  32,042       $   7,817
  Undistributed Net Investment Income                                           36              --
  Accumulated Net Realized Gain (Loss)                                         974             (22)
  Unrealized Depreciation                                                   (2,809)           (386)
                                                                           -------  --------------
                                                                         $  30,243       $   7,409
                                                                           -------  --------------
                                                                           -------  --------------
- -----------------
*Commencement of operations.
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
 
                                      128
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
 
STATEMENT OF CHANGES IN NET ASSETS
- --------------------------------------------------------------------------------
 
THE INTERNATIONAL EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                    YEAR ENDED    YEAR ENDED
                                                                  DECEMBER 31,  DECEMBER 31,
                                                                          1994          1995
                                                                         (000)         (000)
- --------------------------------------------------------------------------------------------
<S>                                                               <C>           <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Income                                           $     13,406  $     19,813
  Net Realized Gain                                                     64,532        88,470
  Change in Unrealized Appreciation (Depreciation)                      46,399        50,978
                                                                  ------------  ------------
  Net Increase in Net Assets Resulting from Operations                 124,337       159,261
                                                                  ------------  ------------
DISTRIBUTIONS:
  Net Investment Income                                                (11,956)       (5,969)
  Net Realized Gain                                                    (18,019)     (168,582)
                                                                  ------------  ------------
  Total Distributions                                                  (29,975)     (174,551)
                                                                  ------------  ------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                           330,843       276,622
  Distributions Reinvested                                              25,762       167,795
  Redeemed                                                             (93,242)     (135,367)
                                                                  ------------  ------------
  Net Increase from Capital Share Transactions                         263,363       309,050
                                                                  ------------  ------------
  Total Increase in Net Assets                                         357,725       293,760
NET ASSETS:
  Beginning of Period                                                  947,045     1,304,770
                                                                  ------------  ------------
  End of Period (2)                                               $  1,304,770  $  1,598,530
                                                                  ------------  ------------
                                                                  ------------  ------------
<FN>
- --------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                     22,148        18,165
  Shares issued on Distributions Reinvested                              1,872        11,272
  Shares Redeemed                                                       (6,156)       (8,961)
                                                                  ------------  ------------
  Net Increase in Capital Shares Outstanding                            17,864        20,476
                                                                  ------------  ------------
                                                                  ------------  ------------
(2) Net Assets were Comprised of:
  Paid in Capital                                                 $  1,001,514  $  1,310,630
  Undistributed Net Investment Income                                    7,083        13,219
  Accumulated Net Realized Gain (Loss)                                  70,335        (2,135)
  Unrealized Appreciation                                              225,838       276,816
                                                                  ------------  ------------
                                                                  $  1,304,770  $  1,598,530
                                                                  ------------  ------------
                                                                  ------------  ------------
</TABLE>
 
- --------------------------------------------------------------------------------
THE INTERNATIONAL SMALL CAP PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                      YEAR ENDED      YEAR ENDED
                                                                    DECEMBER 31,    DECEMBER 31,
                                                                            1994            1995
                                                                           (000)           (000)
- ------------------------------------------------------------------------------------------------
<S>                                                               <C>             <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Income                                                $   1,413       $   3,256
  Net Realized Gain (Loss)                                                (2,342)          7,677
  Change in Unrealized Appreciation (Depreciation)                        (5,180)         (6,811)
                                                                  --------------  --------------
  Net Increase (Decrease) in Net Assets Resulting from
   Operations                                                             (6,109)          4,122
                                                                  --------------  --------------
DISTRIBUTIONS:
  Net Investment Income                                                      (96)         (2,947)
  Net Realized Gain                                                         (794)         (4,763)
                                                                  --------------  --------------
  Total Distributions                                                       (890)         (7,710)
                                                                  --------------  --------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                             132,287          59,699
  Distributions Reinvested                                                   763           6,777
  Redeemed                                                               (18,784)        (24,320)
                                                                  --------------  --------------
  Net Increase from Capital Share Transactions                           114,266          42,156
                                                                  --------------  --------------
  Total Increase in Net Assets                                           107,267          38,568
NET ASSETS:
  Beginning of Period                                                     52,834         160,101
                                                                  --------------  --------------
  End of Period (2)                                                    $ 160,101       $ 198,669
                                                                  --------------  --------------
                                                                  --------------  --------------
<FN>
- ------------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                        8,068           3,865
  Shares Issued on Distributions Reinvested                                   52             453
  Shares Redeemed                                                         (1,164)         (1,584)
                                                                  --------------  --------------
  Net Increase in Capital Shares Outstanding                               6,956           2,734
                                                                  --------------  --------------
                                                                  --------------  --------------
(2) Net Assets were comprised of:
  Paid in Capital                                                      $ 162,928       $ 205,084
  Undistributed Net Investment Income                                        703             715
  Accumulated Net Realized Gain (Loss)                                    (1,989)          1,222
  Unrealized Depreciation                                                 (1,541)         (8,352)
                                                                  --------------  --------------
                                                                       $ 160,101       $ 198,669
                                                                  --------------  --------------
                                                                  --------------  --------------
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
 
                                      129
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
 
STATEMENT OF CHANGES IN NET ASSETS
- --------------------------------------------------------------------------------
 
THE JAPANESE EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                      PERIOD FROM
                                                                        APRIL 25,
                                                                         1994* TO      YEAR ENDED
                                                                     DECEMBER 31,    DECEMBER 31,
                                                                             1994            1995
                                                                            (000)           (000)
- -------------------------------------------------------------------------------------------------
<S>                                                                <C>             <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Income (Loss)                                          $     (31)      $      90
  Net Realized Loss                                                          (527)         (2,999)
  Change in Unrealized Appreciation (Depreciation)                           (215)          5,934
                                                                   --------------  --------------
  Net Increase (Decrease) in Net Assets Resulting from Operations            (773)          3,025
                                                                   --------------  --------------
DISTRIBUTIONS:
  In Excess of Net Investment Income                                           --          (2,539)
                                                                   --------------  --------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                               69,015         132,973
  Distributions Reinvested                                                     --           2,277
  Redeemed                                                                (17,910)        (66,790)
                                                                   --------------  --------------
  Net Increase from Capital Share Transactions                             51,105          68,460
                                                                   --------------  --------------
  Total Increase in Net Assets                                             50,332          68,946
NET ASSETS:
  Beginning of Period                                                          --          50,332
                                                                   --------------  --------------
  End of Period (2)                                                     $  50,332       $ 119,278
                                                                   --------------  --------------
                                                                   --------------  --------------
<FN>
- -------------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                         6,910          15,121
  Shares Issued on Distributions Reinvested                                    --             245
  Shares Redeemed                                                          (1,789)         (7,618)
                                                                   --------------  --------------
  Net Increase in Capital Shares Outstanding                                5,121           7,748
                                                                   --------------  --------------
                                                                   --------------  --------------
(2) Net Assets were comprised of:
  Paid in Capital                                                       $  50,808       $ 119,268
  Accumulated Net Investment Loss/Distributions in Excess of Net
 Investment Income                                                           (261)         (2,710)
  Accumulated Net Realized Loss                                                --          (2,999)
  Unrealized Appreciation (Depreciation)                                     (215)          5,719
                                                                   --------------  --------------
                                                                        $  50,332       $ 119,278
                                                                   --------------  --------------
                                                                   --------------  --------------
- -----------------
* Commencement of operations
</TABLE>
 
- --------------------------------------------------------------------------------
THE LATIN AMERICAN PORTFOLIO
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                                      PERIOD FROM
                                                                                      JANUARY 18,
                                                                                            1995*
                                                                                  TO DECEMBER 31,
                                                                                             1995
                                                                                            (000)
- -------------------------------------------------------------------------------------------------
<S>                                                                               <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Income                                                                 $      82
  Net Realized Loss                                                                          (543)
  Change in Unrealized Appreciation                                                           208
                                                                                          -------
  Net Decrease in Net Assets Resulting from Operations                                       (253)
                                                                                          -------
DISTRIBUTIONS:
  Net Investment Income                                                                       (74)
  Return of Capital                                                                           (49)
                                                                                          -------
  Total Distributions                                                                        (123)
                                                                                          -------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                                               21,860
  Distributions Reinvested                                                                    108
  Redeemed                                                                                 (6,216)
                                                                                          -------
  Net Increase from Capital Share Transactions                                             15,752
                                                                                          -------
  Total Increase in Net Assets                                                             15,376
NET ASSETS:
  Beginning of Period                                                                          --
                                                                                          -------
  End of Period (2)                                                                     $  15,376
                                                                                          -------
                                                                                          -------
<FN>
- -------------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                                         2,375
  Shares Issued on Distributions Reinvested                                                    12
  Shares Redeemed                                                                            (690)
                                                                                          -------
  Net Increase in Capital Shares Outstanding                                                1,697
                                                                                          -------
                                                                                          -------
(2) Net Assets were comprised of:
  Paid in Capital                                                                       $  15,698
  Accumulated Net Realized Loss                                                              (530)
  Unrealized Appreciation                                                                     208
                                                                                          -------
                                                                                        $  15,376
                                                                                          -------
                                                                                          -------
- -----------------
*Commencement of operations
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
 
                                      130
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
 
STATEMENT OF CHANGES IN NET ASSETS
- --------------------------------------------------------------------------------
 
THE AGGRESSIVE EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                                     PERIOD FROM
                                                                                  MARCH 8, 1995*
                                                                                 TO DECEMBER 31,
                                                                                            1995
                                                                                           (000)
- ------------------------------------------------------------------------------------------------
<S>                                                                             <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Income                                                                $     266
  Net Realized Gain                                                                        4,041
  Change in Unrealized Appreciation                                                        1,860
                                                                                         -------
  Net Increase in Net Assets Resulting from Operations                                     6,167
                                                                                         -------
DISTRIBUTIONS:
  Net Investment Income                                                                     (268)
  Net Realized Gain                                                                       (3,617)
                                                                                         -------
  Total Distributions                                                                     (3,885)
                                                                                         -------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                                              26,611
  Distributions Reinvested                                                                 3,556
  Redeemed                                                                                (3,901)
                                                                                         -------
  Net Increase from Capital Share Transactions                                            26,266
                                                                                         -------
  Total Increase in Net Assets                                                            28,548
NET ASSETS:
  Beginning of Period                                                                         --
                                                                                         -------
  End of Period (2)                                                                    $  28,548
                                                                                         -------
                                                                                         -------
<FN>
- ------------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                                        2,360
  Shares Issued on Distributions Reinvested                                                  293
  Shares Redeemed                                                                           (308)
                                                                                         -------
  Net Increase in Capital Shares Outstanding                                               2,345
                                                                                         -------
                                                                                         -------
(2) Net Assets were comprised of:
  Paid in Capital                                                                      $  26,266
  Accumulated Net Realized Gain                                                              422
  Unrealized Appreciation                                                                  1,860
                                                                                         -------
                                                                                       $  28,548
                                                                                         -------
                                                                                         -------
- -----------------
*Commencement of operations.
</TABLE>
 
- --------------------------------------------------------------------------------
THE EMERGING GROWTH PORTFOLIO
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                       YEAR ENDED      YEAR ENDED
                                                                     DECEMBER 31,    DECEMBER 31,
                                                                             1994            1995
                                                                            (000)           (000)
- -------------------------------------------------------------------------------------------------
<S>                                                                <C>             <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Loss                                                   $    (673)      $  (1,009)
  Net Realized Gain                                                         1,331          11,225
  Change in Unrealized Appreciation (Depreciation)                           (891)         27,942
                                                                   --------------  --------------
  Net Increase (Decrease) in Net Assets Resulting from Operations            (233)         38,158
                                                                   --------------  --------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                               85,970         100,167
  Redeemed                                                                (71,689)       (136,616)
                                                                   --------------  --------------
  Net Increase (Decrease) from Capital Share Transactions                  14,281         (36,449)
                                                                   --------------  --------------
  Total Increase in Net Assets                                             14,048           1,709
NET ASSETS:
  Beginning of Period                                                     103,621         117,669
                                                                   --------------  --------------
  End of Period (2)                                                     $ 117,669       $ 119,378
                                                                   --------------  --------------
                                                                   --------------  --------------
<FN>
- -------------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                         5,433           5,737
  Shares Redeemed                                                          (4,522)         (7,483)
                                                                   --------------  --------------
  Net Increase (Decrease) in Capital Shares Outstanding                       911          (1,746)
                                                                   --------------  --------------
                                                                   --------------  --------------
(2) Net Assets were comprised of:
  Paid in Capital                                                       $ 103,598       $  66,140
  Accumulated Net Realized Gain (Loss)                                    (10,925)            300
  Unrealized Appreciation                                                  24,996          52,938
                                                                   --------------  --------------
                                                                        $ 117,669       $ 119,378
                                                                   --------------  --------------
                                                                   --------------  --------------
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
 
                                      131
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
 
STATEMENT OF CHANGES IN NET ASSETS
- --------------------------------------------------------------------------------
 
THE EQUITY GROWTH PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                  YEAR ENDED      YEAR ENDED
                                                                DECEMBER 31,    DECEMBER 31,
                                                                        1994            1995
                                                                       (000)           (000)
- --------------------------------------------------------------------------------------------
<S>                                                           <C>             <C>
INCREASE (DECREASE) IN NET ASSSETS
OPERATIONS:
  Net Investment Income                                            $   1,293       $   2,169
  Net Realized Gain                                                    3,710          32,477
  Change in Unrealized Appreciation (Depreciation)                    (2,690)         15,685
                                                              --------------  --------------
  Net Increase in Net Assets Resulting from Operations                 2,313          50,331
                                                              --------------  --------------
DISTRIBUTIONS:
  Net Investment Income                                                 (952)         (2,636)
  Net Realized Gain                                                   (2,220)        (26,092)
                                                              --------------  --------------
  Total Distributions                                                 (3,172)        (28,728)
                                                              --------------  --------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                          47,456          78,470
  Distributions Reinvested                                             3,096          26,785
  Redeemed                                                           (26,223)        (66,005)
                                                              --------------  --------------
  Net Increase from Capital Share Transactions                        24,329          39,250
                                                              --------------  --------------
  Total Increase in Net Assets                                        23,470          60,853
NET ASSETS:
  Beginning of Period                                                 73,789          97,259
                                                              --------------  --------------
  End of Period (2)                                                $  97,259       $ 158,112
                                                              --------------  --------------
                                                              --------------  --------------
<FN>
- --------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                    3,964           5,794
  Shares Issued on Distributions Reinvested                              267           1,955
  Shares Redeemed                                                     (2,218)         (4,657)
                                                              --------------  --------------
  Net Increase in Capital Shares Outstanding                           2,013           3,092
                                                              --------------  --------------
                                                              --------------  --------------
(2) Net Assets were comprised of:
  Paid in Capital                                             $       92,584  $      131,834
  Undistributed Net Investment Income                                    461              --
  Accumulated Net Realized Gain                                        3,459           9,838
  Unrealized Appreciation                                                755          16,440
                                                              --------------  --------------
                                                              $       97,259  $      158,112
                                                              --------------  --------------
                                                              --------------  --------------
</TABLE>
 
- --------------------------------------------------------------------------------
THE SMALL CAP VALUE EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                       YEAR ENDED      YEAR ENDED
                                                                         DECEMBER    DECEMBER 31,
                                                                         31, 1994            1995
                                                                            (000)           (000)
- -------------------------------------------------------------------------------------------------
<S>                                                                   <C>          <C>
INCREASE (DECREASE) IN NET ASSSETS
OPERATIONS:
  Net Investment Income                                                 $     951       $   1,223
  Net Realized Gain                                                         1,484           1,546
  Change in Unrealized Appreciation (Depreciation)                         (1,598)          5,880
                                                                      -----------  --------------
  Net Increase in Net Assets Resulting from Operations                        837           8,649
                                                                      -----------  --------------
DISTRIBUTIONS:
  Net Investment Income                                                      (831)         (1,519)
  Net Realized Gain                                                          (720)         (2,511)
                                                                      -----------  --------------
  Total Distributions                                                      (1,551)         (4,030)
                                                                      -----------  --------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                               25,447          18,293
  Distributions Reinvested                                                  1,464           3,611
  Redeemed                                                                (12,939)        (14,637)
                                                                      -----------  --------------
  Net Increase from Capital Share Transactions                             13,972           7,267
                                                                      -----------  --------------
  Total Increase in Net Assets                                             13,258          11,886
NET ASSETS:
  Beginning of Period                                                      26,775          40,033
                                                                      -----------  --------------
  End of Period (2)                                                     $  40,033       $  51,919
                                                                      -----------  --------------
                                                                      -----------  --------------
<FN>
- -------------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
   Shares Subscribed                                                        2,358           1,631
   Shares Issued on Distributions Reinvested                                  137             324
   Shares Redeemed                                                         (1,200)         (1,304)
                                                                      -----------  --------------
   Net Increase in Capital Shares Outstanding                               1,295             651
                                                                      -----------  --------------
                                                                      -----------  --------------
(2) Net Assets were comprised of:
   Paid in Capital                                                      $  39,194       $  46,460
   Undistributed Net Investment Income                                        281              --
   Accumulated Net Realized Gain                                            1,484             505
   Unrealized Appreciation (Depreciation)                                    (926)          4,954
                                                                      -----------  --------------
                                                                        $  40,033       $  51,919
                                                                      -----------  --------------
                                                                      -----------  --------------
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
 
                                      132
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
 
STATEMENT OF CHANGES IN NET ASSETS
- --------------------------------------------------------------------------------
 
THE U.S. REAL ESTATE PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                                      PERIOD FROM
                                                                                     FEBRUARY 24,
                                                                                         1995* TO
                                                                                DECEMBER 31, 1995
                                                                                            (000)
- -------------------------------------------------------------------------------------------------
<S>                                                                             <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Income                                                                 $   1,526
  Net Realized Gain                                                                         3,495
  Change in Unrealized Appreciation                                                         3,896
                                                                                          -------
  Net Increase in Net Assets Resulting from Operations                                      8,917
                                                                                          -------
DISTRIBUTIONS:
  Net Investment Income                                                                    (1,405)
  Net Realized Gain                                                                        (2,504)
                                                                                          -------
  Total Distributions                                                                      (3,909)
                                                                                          -------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                                               67,651
  Distributions Reinvested                                                                  3,148
  Redeemed                                                                                 (6,298)
                                                                                          -------
  Net Increase from Capital Share Transactions                                             64,501
                                                                                          -------
  Total Increase in Net Assets                                                             69,509
NET ASSETS:
  Beginning of Period                                                                          --
                                                                                          -------
  End of Period (2)                                                                     $  69,509
                                                                                          -------
                                                                                          -------
<FN>
- -------------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                                         6,381
  Shares Issued on Distributions Reinvested                                                   279
  Shares Redeemed                                                                            (573)
                                                                                          -------
  Net Increase in Capital Shares Outstanding                                                6,087
                                                                                          -------
                                                                                          -------
(2) Net Assets were comprised of:
  Paid in Capital                                                                       $  64,501
  Undistributed Net Investment Income                                                         121
  Accumulated Net Realized Gain                                                               991
  Unrealized Appreciation                                                                   3,896
                                                                                          -------
                                                                                        $  69,509
                                                                                          -------
                                                                                          -------
- -----------------
*Commencement of operations
</TABLE>
 
- --------------------------------------------------------------------------------
THE VALUE EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                         YEAR ENDED      YEAR ENDED
                                                                       DECEMBER 31,    DECEMBER 31,
                                                                               1994            1995
                                                                              (000)           (000)
- ---------------------------------------------------------------------------------------------------
<S>                                                                  <C>             <C>
INCREASE (DECREASE) IN NET ASSSETS
OPERATIONS:
  Net Investment Income                                                   $   2,376       $   3,434
  Net Realized Gain                                                           2,378          10,276
  Change in Unrealized Appreciation (Depreciation)                           (6,089)         17,116
                                                                     --------------  --------------
  Net Increase (Decrease) in Net Assets Resulting from Operations            (1,335)         30,826
                                                                     --------------  --------------
DISTRIBUTIONS:
  Net Investment Income                                                      (2,189)         (4,042)
  Net Realized Gain                                                          (2,504)         (6,330)
                                                                     --------------  --------------
  Total Distributions                                                        (4,693)        (10,372)
                                                                     --------------  --------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                                 45,372          70,393
  Distributions Reinvested                                                    4,395           9,289
  Redeemed                                                                  (24,931)        (26,177)
                                                                     --------------  --------------
  Net Increase from Capital Share Transactions                               24,836          53,505
                                                                     --------------  --------------
  Total Increase in Net Assets                                               18,808          73,959
 
NET ASSETS:
  Beginning of Period                                                        54,598          73,406
                                                                     --------------  --------------
  End of Period (2)                                                       $  73,406       $ 147,365
                                                                     --------------  --------------
                                                                     --------------  --------------
<FN>
- ---------------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                           3,798           5,522
  Shares Issued on Distributions Reinvested                                     372             731
  Shares Redeemed                                                            (2,109)         (2,068)
                                                                     --------------  --------------
  Net Increase in Capital Shares Outstanding                                  2,061           4,185
                                                                     --------------  --------------
                                                                     --------------  --------------
(2) Net Assets were comprised of:
  Paid in Capital                                                         $  72,751       $ 126,256
  Undistributed Net Investment Income                                           643               8
  Accumulated Net Realized Gain                                               2,307           6,280
  Unrealized Appreciation (Depreciation)                                     (2,295)         14,821
                                                                     --------------  --------------
                                                                          $  73,406       $ 147,365
                                                                     --------------  --------------
                                                                     --------------  --------------
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
 
                                      133
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
 
STATEMENT OF CHANGES IN NET ASSETS
- --------------------------------------------------------------------------------
 
THE BALANCED PORTFOLIO
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                       YEAR ENDED       YEAR ENDED
                                                                     DECEMBER 31,     DECEMBER 31,
                                                                             1994             1995
                                                                            (000)            (000)
- --------------------------------------------------------------------------------------------------
<S>                                                                <C>             <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Income                                                 $     987        $     868
  Net Realized Gain                                                           496            1,158
  Change in Unrealized Appreciation (Depreciation)                         (1,998)           2,413
                                                                   --------------          -------
  Net Increase (Decrease) in Net Assets Resulting from Operations            (515)           4,439
                                                                   --------------          -------
DISTRIBUTIONS:
  Net Investment Income                                                    (1,257)          (1,080)
  Net Realized Gain                                                        (3,880)          (1,047)
                                                                   --------------          -------
  Total Distributions                                                      (5,137)          (2,127)
                                                                   --------------          -------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                                4,396            3,530
  Distributions Reinvested                                                  4,725            1,695
  Redeemed                                                                (14,661)          (3,387)
                                                                   --------------          -------
  Net Increase (Decrease) from Capital Share Transactions                  (5,540)           1,838
                                                                   --------------          -------
  Total Increase (Decrease) in Net Assets                                 (11,192)           4,150
NET ASSETS:
  Beginning of Period                                                      29,684           18,492
                                                                   --------------          -------
  End of Period (2)                                                     $  18,492        $  22,642
                                                                   --------------          -------
                                                                   --------------          -------
<FN>
- --------------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                           470              380
  Shares Issued on Distributions Reinvested                                   502              182
  Shares Redeemed                                                          (1,574)            (358)
                                                                   --------------          -------
  Net Increase (Decrease) in Capital Shares Outstanding                      (602)             204
                                                                   --------------          -------
                                                                   --------------          -------
(2) Net Assets were comprised of:
  Paid in Capital                                                       $  18,279        $  20,117
  Undistributed Net Investment Income                                         214                2
  Accumulated Net Realized Gain                                               495              606
  Unrealized Appreciation (Depreciation)                                     (496)           1,917
                                                                   --------------          -------
                                                                        $  18,492        $  22,642
                                                                   --------------          -------
                                                                   --------------          -------
</TABLE>
 
- --------------------------------------------------------------------------------
THE EMERGING MARKETS DEBT PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                      PERIOD FROM
                                                                      FEBRUARY 1,
                                                                            1994*      YEAR ENDED
                                                                  TO DECEMBER 31,    DECEMBER 31,
                                                                             1994            1995
                                                                            (000)           (000)
- -------------------------------------------------------------------------------------------------
<S>                                                              <C>               <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Income                                                 $   8,511       $  25,020
  Net Realized Gain (Loss)                                                 (2,516)          9,187
  Change in Unrealized Appreciation (Depreciation)                         (9,457)         15,290
                                                                         --------  --------------
  Net Increase (Decrease) in Net Assets Resulting from
   Operations                                                              (3,462)         49,497
                                                                         --------  --------------
DISTRIBUTIONS:
  Net Investment Income                                                        --         (33,418)
  Net Realized Gain                                                            --          (7,508)
                                                                         --------  --------------
  Total Distributions                                                          --         (40,926)
                                                                         --------  --------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                              190,661         147,278
  Distributions Reinvested                                                     --          29,155
  Redeemed                                                                (42,250)       (148,075)
                                                                         --------  --------------
  Net Increase from Capital Share Transactions                            148,411          28,358
                                                                         --------  --------------
  Total Increase in Net Assets                                            144,949          36,929
NET ASSETS:
  Beginning of Period                                                          --         144,949
                                                                         --------  --------------
  End of Period (2)                                                     $ 144,949       $ 181,878
                                                                         --------  --------------
                                                                         --------  --------------
<FN>
- -------------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                        21,753          18,475
  Shares issued on Distributions Reinvested                                    --           3,468
  Shares Redeemed                                                          (4,872)        (17,651)
                                                                         --------  --------------
  Net Increase in Capital Shares Outstanding                               16,881           4,292
                                                                         --------  --------------
                                                                         --------  --------------
(2) Net Assets were comprised of:
  Paid in Capital                                                       $ 148,411       $ 176,769
  Undistributed (Distributions in Excess of) Net Investment
 Income                                                                     8,322          (1,501)
  Accumulated Net Realized Gain (Loss)                                     (2,327)            777
  Unrealized Appreciation (Depreciation)                                   (9,457)          5,833
                                                                         --------  --------------
                                                                        $ 144,949       $ 181,878
                                                                         --------  --------------
                                                                         --------  --------------
- -----------------
* Commencement of operations.
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
 
                                      134
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
 
STATEMENT OF CHANGES IN NET ASSETS
- --------------------------------------------------------------------------------
 
THE FIXED INCOME PORTFOLIO
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                       YEAR ENDED      YEAR ENDED
                                                                     DECEMBER 31,    DECEMBER 31,
                                                                             1994            1995
                                                                            (000)           (000)
- -------------------------------------------------------------------------------------------------
<S>                                                                <C>             <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Income                                                 $  12,421       $  12,208
  Net Realized Gain (Loss)                                                (14,879)          5,921
  Change in Unrealized Appreciation (Depreciation)                         (5,219)         13,125
                                                                   --------------  --------------
  Net Increase (Decrease) in Net Assets Resulting from Operations          (7,677)         31,254
                                                                   --------------  --------------
DISTRIBUTIONS:
  Net Investment Income                                                   (11,181)        (13,570)
  Net Realized Gain                                                        (8,092)             --
  In Excess of Net Realized Gain                                              (22)             --
                                                                   --------------  --------------
  Total Distributions                                                     (19,295)        (13,570)
                                                                   --------------  --------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                               91,618          67,883
  Distributions Reinvested                                                 16,756          10,529
  Redeemed                                                               (112,739)       (139,900)
                                                                   --------------  --------------
  Net Decrease from Capital Share Transactions                             (4,365)        (61,488)
                                                                   --------------  --------------
  Total Decrease in Net Assets                                            (31,337)        (43,804)
NET ASSETS:
  Beginning of Period                                                     240,668         209,331
                                                                   --------------  --------------
  End of Period (2)                                                     $ 209,331       $ 165,527
                                                                   --------------  --------------
                                                                   --------------  --------------
<FN>
- -------------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscriptions                                                      9,049           6,668
  Shares Issued on Distributions Reinvested                                 1,625           1,022
  Shares Redeemed                                                         (11,150)        (13,696)
                                                                   --------------  --------------
  Net Decrease in Capital Shares Outstanding                                 (476)         (6,006)
                                                                   --------------  --------------
                                                                   --------------  --------------
(2) Net Assets were comprised of:
  Paid in Capital                                                       $ 227,051       $ 165,563
  Undistributed Net Investment Income                                       1,274              10
  Accumulated Net Realized Loss                                           (14,154)         (8,331)
  Unrealized Appreciation (Depreciation)                                   (4,840)          8,285
                                                                   --------------  --------------
                                                                        $ 209,331       $ 165,527
                                                                   --------------  --------------
                                                                   --------------  --------------
</TABLE>
 
- --------------------------------------------------------------------------------
THE GLOBAL FIXED INCOME PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                       YEAR ENDED      YEAR ENDED
                                                                     DECEMBER 31,    DECEMBER 31,
                                                                             1994            1995
                                                                            (000)           (000)
- -------------------------------------------------------------------------------------------------
<S>                                                                <C>             <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Income                                                 $   9,291       $   6,508
  Net Realized Gain (Loss)                                                 (9,075)             15
  Change in Unrealized Appreciation (Depreciation)                        (10,682)         10,191
                                                                   --------------  --------------
  Net Increase (Decrease) in Net Assets Resulting from Operations         (10,466)         16,714
                                                                   --------------  --------------
DISTRIBUTIONS:
  Net Investment Income                                                    (5,595)         (9,003)
  Net Realized Gain                                                        (4,564)             --
                                                                   --------------  --------------
  Total Distributions                                                     (10,159)         (9,003)
                                                                   --------------  --------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                               96,510          36,622
  Distributions Reinvested                                                  9,111           7,887
  Redeemed                                                               (126,789)        (80,043)
                                                                   --------------  --------------
  Net Decrease from Capital Share Transactions                            (21,168)        (35,534)
                                                                   --------------  --------------
  Total Decrease in Net Assets                                            (41,793)        (27,823)
NET ASSETS:
  Beginning of Period                                                     172,468         130,675
                                                                   --------------  --------------
  End of Period (2)                                                     $ 130,675       $ 102,852
                                                                   --------------  --------------
                                                                   --------------  --------------
<FN>
- -------------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                         8,912           3,346
  Shares Issued on Distributions Reinvested                                   833             737
  Shares Redeemed                                                         (11,801)         (7,623)
                                                                   --------------  --------------
  Net Decrease in Capital Shares Outstanding                               (2,056)         (3,540)
                                                                   --------------  --------------
                                                                   --------------  --------------
(2) Net Assets were comprised of:
  Paid in Capital                                                       $ 141,657       $ 106,123
  Undistributed Net Investment Income                                       1,613             309
  Accumulated Net Realized Loss                                            (5,933)         (7,109)
  Unrealized Appreciation (Depreciation)                                   (6,662)          3,529
                                                                   --------------  --------------
                                                                        $ 130,675       $ 102,852
                                                                   --------------  --------------
                                                                   --------------  --------------
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
 
                                      135
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
 
STATEMENT OF CHANGES IN NET ASSETS
- --------------------------------------------------------------------------------
 
THE HIGH YIELD PORTFOLIO
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                       YEAR ENDED      YEAR ENDED
                                                                     DECEMBER 31,    DECEMBER 31,
                                                                             1994            1995
                                                                            (000)           (000)
- -------------------------------------------------------------------------------------------------
<S>                                                                <C>             <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Income                                                 $   9,341       $   7,477
  Net Realized Loss                                                        (1,581)         (3,145)
  Change in Unrealized Appreciation (Depreciation)                        (12,785)          9,886
                                                                   --------------  --------------
  Net Increase (Decrease) in Net Assets Resulting from Operations          (5,025)         14,218
                                                                   --------------  --------------
DISTRIBUTIONS:
  Net Investment Income                                                    (9,097)         (8,122)
  Net Realized Gain                                                        (1,413)             --
                                                                   --------------  --------------
  Total Distributions                                                     (10,510)         (8,122)
                                                                   --------------  --------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                               72,764          59,247
  Distributions Reinvested                                                  8,869           6,088
  Redeemed                                                                (43,375)       (106,409)
                                                                   --------------  --------------
  Net Increase (Decrease) from Capital Share Transactions                  38,258         (41,074)
                                                                   --------------  --------------
  Total Increase (Decrease) in Net Assets                                  22,723         (34,978)
NET ASSETS:
  Beginning of Period                                                      74,500          97,223
                                                                   --------------  --------------
  End of Period (2)                                                     $  97,223       $  62,245
                                                                   --------------  --------------
                                                                   --------------  --------------
<FN>
- -------------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                         6,882           5,865
  Shares Issued on Distributions Reinvested                                   858             609
  Shares Redeemed                                                          (4,235)        (10,704)
                                                                   --------------  --------------
  Net Increase (Decrease) in Capital Shares Outstanding                     3,505          (4,230)
                                                                   --------------  --------------
                                                                   --------------  --------------
(2) Net Assets were comprised of:
  Paid in Capital                                                       $ 108,726       $  67,652
  Undistributed Net Investment Income                                         731              86
  Accumulated Net Realized Loss                                            (1,581)         (4,726)
  Unrealized Depreciation                                                 (10,653)           (767)
                                                                   --------------  --------------
                                                                        $  97,223       $  62,245
                                                                   --------------  --------------
                                                                   --------------  --------------
</TABLE>
 
- --------------------------------------------------------------------------------
THE MUNICIPAL BOND PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                                     PERIOD FROM
                                                                                     JANUARY 18,
                                                                                           1995*
                                                                                 TO DECEMBER 31,
                                                                                            1995
                                                                                           (000)
- ------------------------------------------------------------------------------------------------
<S>                                                                             <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Income                                                                $   1,963
  Net Realized Gain                                                                          193
  Change in Unrealized Appreciation                                                        1,635
                                                                                        --------
  Net Increase in Net Assets Resulting from Operations                                     3,791
                                                                                        --------
DISTRIBUTIONS:
  Net Investment Income                                                                   (1,963)
  In Excess of Net Investment Income                                                         (15)
  Net Realized Gain                                                                         (193)
                                                                                        --------
  Total Distributions                                                                     (2,171)
                                                                                        --------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                                              61,800
  Distributions Reinvested                                                                 2,060
  Redeemed                                                                               (19,611)
                                                                                        --------
  Net Increase from Capital Share Transactions                                            44,249
                                                                                        --------
  Total Increase in Net Assets                                                            45,869
NET ASSETS:
  Beginning of Period                                                                         --
                                                                                        --------
  End of Period (2)                                                                    $  45,869
                                                                                        --------
                                                                                        --------
<FN>
- ------------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                                        6,134
  Shares Issued on Distributions Reinvested                                                  200
  Shares Redeemed                                                                         (1,912)
                                                                                        --------
  Net Increase in Capital Shares Outstanding                                               4,422
                                                                                        --------
                                                                                        --------
(2) Net Assets were comprised of:
  Paid in Capital                                                                      $  44,249
  Distributions in Excess of Net Investment Income                                           (15)
  Unrealized Appreciation                                                                  1,635
                                                                                        --------
                                                                                       $  45,869
                                                                                        --------
                                                                                        --------
- -----------------
*Commencement of operations.
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
 
                                      136
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
 
STATEMENT OF CHANGES IN NET ASSETS
- --------------------------------------------------------------------------------
 
THE MONEY MARKET PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                      YEAR ENDED     YEAR ENDED
                                                                    DECEMBER 31,   DECEMBER 31,
                                                                            1994           1995
                                                                           (000)          (000)
- -----------------------------------------------------------------------------------------------
<S>                                                                <C>            <C>
INCREASE (DECREASE) IN NET ASSSETS
OPERATIONS:
  Net Investment Income                                                $  26,880      $  44,657
  Net Realized Gain (Loss)                                                   (26)            79
                                                                   -------------  -------------
  Net Increase in Net Assets Resulting from Operations                    26,854         44,736
                                                                   -------------  -------------
DISTRIBUTIONS:
  Net Investment Income                                                  (26,888)       (44,657)
                                                                   -------------  -------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                           4,547,025      8,093,985
  Distributions Reinvested                                                24,451         41,765
  Redeemed                                                            (4,538,102)    (7,989,639)
                                                                   -------------  -------------
  Net Increase from Capital Share Transactions                            33,374        146,111
                                                                   -------------  -------------
  Total Increase in Net Assets                                            33,340        146,190
NET ASSETS:
  Beginning of Period                                                    657,163        690,503
                                                                   -------------  -------------
  End of Period (2)                                                    $ 690,503      $ 836,693
                                                                   -------------  -------------
                                                                   -------------  -------------
<FN>
- -----------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                    4,547,025      8,093,987
  Shares Issued on Distributions Reinvested                               24,451         41,765
  Shares Redeemed                                                     (4,538,102)    (7,989,639)
                                                                   -------------  -------------
  Net Increase in Capital Shares Outstanding                              33,374        146,113
                                                                   -------------  -------------
                                                                   -------------  -------------
(2) Net Assets were comprised of:
  Paid in Capital                                                      $ 690,595      $ 836,706
  Accumulated Net Realized Loss                                              (92)           (13)
                                                                   -------------  -------------
                                                                       $ 690,503      $ 836,693
                                                                   -------------  -------------
                                                                   -------------  -------------
</TABLE>
 
- --------------------------------------------------------------------------------
THE MUNICIPAL MONEY MARKET PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                      YEAR ENDED     YEAR ENDED
                                                                    DECEMBER 31,   DECEMBER 31,
                                                                            1994           1995
                                                                           (000)          (000)
- -----------------------------------------------------------------------------------------------
<S>                                                                <C>            <C>
INCREASE (DECREASE) IN NET ASSETS
OPERATIONS:
  Net Investment Income                                                $   8,186      $  13,579
  Net Realized Loss                                                           (6)            (1)
                                                                   -------------  -------------
  Net Increase in Net Assets Resulting from Operations                     8,180         13,578
                                                                   -------------  -------------
DISTRIBUTIONS:
  Net Investment Income                                                   (8,186)       (13,579)
                                                                   -------------  -------------
CAPITAL SHARE TRANSACTIONS: (1)
  Subscribed                                                           2,267,352      3,169,110
  Distributions Reinvested                                                 7,587         13,182
  Redeemed                                                            (2,182,013)    (3,090,216)
                                                                   -------------  -------------
  Net Increase from Capital Share Transactions                            92,926         92,076
                                                                   -------------  -------------
  Total Increase in Net Assets                                            92,920         92,075
NET ASSETS:
  Beginning of Period                                                    266,524        359,444
                                                                   -------------  -------------
  End of Period (2)                                                    $ 359,444      $ 451,519
                                                                   -------------  -------------
                                                                   -------------  -------------
<FN>
- -----------------------------------------------------------------------------------------------
(1) Capital Share Transactions:
  Shares Subscribed                                                    2,267,352      3,169,110
  Shares Issued on Distributions Reinvested                                7,587         13,182
  Shares Redeemed                                                     (2,182,013)    (3,090,216)
                                                                   -------------  -------------
  Net Increase in Capital Shares Outstanding                              92,926         92,076
                                                                   -------------  -------------
                                                                   -------------  -------------
(2) Net Assets were comprised of:
  Paid in Capital                                                      $ 359,452      $ 451,528
  Accumulated Net Realized Loss                                               (8)            (9)
                                                                   -------------  -------------
                                                                       $ 359,444      $ 451,519
                                                                   -------------  -------------
                                                                   -------------  -------------
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
 
                                      137
<PAGE>
[LOGO]  Morgan Stanley
    Institutional Fund, Inc.
- --------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS
SELECTED PER SHARE DATA AND RATIOS:
- --------------------------------------------------------------------------------
 
THE ACTIVE COUNTRY ALLOCATION PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                              PERIOD FROM
                                        JANUARY 17, 1992*       TWO MONTHS
                                                       TO            ENDED       YEAR ENDED       YEAR ENDED       YEAR ENDED
                                              OCTOBER 31,     DECEMBER 31,     DECEMBER 31,     DECEMBER 31,     DECEMBER 31,
                                                     1992             1992             1993             1994             1995
- -----------------------------------------------------------------------------------------------------------------------------
<S>                                    <C>                    <C>              <C>              <C>              <C>
NET ASSET VALUE, BEGINNING OF PERIOD   $            10.00     $      9.37      $       9.59     $      12.21     $      11.65
                                                   ------           -----            ------           ------           ------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)                          0.11            0.02              0.13             0.19             0.17
  Net Realized and Unrealized Gain
   (Loss) on Investments                            (0.74)           0.20              2.75            (0.25)            1.00
                                                   ------           -----            ------           ------           ------
    Total from Investment Operations                (0.63)           0.22              2.88            (0.06)            1.17
                                                   ------           -----            ------           ------           ------
DISTRIBUTIONS
  Net Investment Income                                --              --             (0.09)           (0.14)           (0.25)
  In Excess of Net Investment Income                   --              --             (0.08)              --            (0.10)
  Net Realized Gain                                    --              --                --            (0.36)           (0.84)
  In Excess of Net Realized Gain                       --              --             (0.09)              --               --
                                                   ------           -----            ------           ------           ------
    Total Distributions                                --              --             (0.26)           (0.50)           (1.19)
                                                   ------           -----            ------           ------           ------
NET ASSET VALUE, END OF PERIOD         $             9.37     $      9.59      $      12.21     $      11.65     $      11.63
                                                   ------           -----            ------           ------           ------
                                                   ------           -----            ------           ------           ------
TOTAL RETURN                                        (6.30)%          2.35%            30.72%           (0.52)%          10.57%
                                                   ------           -----            ------           ------           ------
                                                   ------           -----            ------           ------           ------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)             $47,534         $50,234          $150,854         $182,977         $170,663
Ratio of Expenses to Average Net
   Assets                                            0.88%**         0.80%**           0.80%            0.80%            0.80%
Ratio of Net Investment Income to
   Average Net Assets                                2.32%**         1.22%**           1.29%            1.43%            1.26%
Portfolio Turnover Rate                                62%              2%               53%              51%              72%
<FN>
- -----------------
(1) Effect of voluntary expense
   limitation during the period:
    Per share benefit to net
     investment income                 $             0.03     $      0.01      $       0.05     $       0.03     $       0.05
  Ratios before expense limitation:
    Expenses to Average Net Assets                   1.58%**         1.70%**           1.33%            1.00%            1.18%
    Net Investment Income to Average
     Net Assets                                      1.62%**         0.32%**           0.76%            1.23%            0.88%
 *Commencement of operations.
**Annualized
</TABLE>
 
- --------------------------------------------------------------------------------
THE ASIAN EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                     PERIOD FROM
                                         JULY 1,                      TWO MONTHS
                                        1991* TO      YEAR ENDED           ENDED      YEAR ENDED      YEAR ENDED      YEAR ENDED
                                     OCTOBER 31,     OCTOBER 31,    DECEMBER 31,    DECEMBER 31,    DECEMBER 31,    DECEMBER 31,
                                            1991            1992            1992            1993            1994            1995
- --------------------------------------------------------------------------------------------------------------------------------
<S>                                  <C>            <C>             <C>             <C>             <C>             <C>
NET ASSET VALUE, BEGINNING OF
 PERIOD                                  $10.00     $       9.67    $      13.63    $      13.11    $      26.20    $      21.54
                                          -----           ------          ------          ------          ------          ------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)                0.03             0.14            0.01            0.10            0.11            0.18
  Net Realized and Unrealized Gain
   (Loss) on Investments                  (0.36)            3.86           (0.53)          13.38           (4.15)           1.11
                                          -----           ------          ------          ------          ------          ------
    Total from Investment
     Operations                           (0.33)            4.00           (0.52)          13.48           (4.04)           1.29
                                          -----           ------          ------          ------          ------          ------
DISTRIBUTIONS
  Net Investment Income                      --            (0.04)             --           (0.01)          (0.09)          (0.34)
  In Excess of Net Investment
   Income                                    --               --              --           (0.13)             --           (0.00)+
  Net Realized Gain                          --               --              --           (0.12)          (0.53)          (3.01)
  In Excess of Net Realized Gain             --               --              --           (0.13)             --              --
                                          -----           ------          ------          ------          ------          ------
    Total Distributions                      --            (0.04)             --           (0.39)          (0.62)          (3.35)
                                          -----           ------          ------          ------          ------          ------
NET ASSET VALUE, END OF PERIOD       $     9.67     $      13.63    $      13.11    $      26.20    $      21.54    $      19.48
                                          -----           ------          ------          ------          ------          ------
                                          -----           ------          ------          ------          ------          ------
TOTAL RETURN                              (3.30)%          41.50%          (3.82)%        105.71%         (15.81)%          6.87%
                                          -----           ------          ------          ------          ------          ------
                                          -----           ------          ------          ------          ------          ------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period
 (Thousands)                            $10,719          $41,017         $41,978        $287,136        $276,906        $314,884
Ratio of Expenses to Average Net
 Assets (1)                                1.00%**          1.00%           1.00%**         1.00%           1.00%           1.00%
Ratio of Net Investment Income to
 Average Net Assets (1)                    1.13%**          1.53%           0.61%**         0.83%           0.52%           0.97%
Portfolio Turnover Rate                       2%              33%             10%             18%             47%             42%
<FN>
- -----------------
(1) Effect of voluntary expense
limitation
    during the period:
    Per share benefit to net
     investment income               $     0.02     $       0.06    $       0.02    $       0.05    $       0.04    $       0.03
  Ratios before expense limitation:
    Expenses to Average Net Assets         2.52%**          1.63%           2.02%**         1.38%           1.20%           1.18%
    Net Investment Income (Loss) to
     Average
      Net Assets                          (0.39)%**         0.90%          (0.41)%**         0.45%          0.32%           0.79%
 *Commencement of operations.
**Annualized
 +Amount is less than $0.01 per
 share.
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
                                      138
<PAGE>
[LOGO]  Morgan Stanley
    Institutional Fund, Inc.
- --------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS
SELECTED PER SHARE DATA AND RATIOS:
- --------------------------------------------------------------------------------
 
THE EMERGING MARKETS PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                            PERIOD FROM
                                    SEPTEMBER 25, 1992*       TWO MONTHS
                                                     TO            ENDED       YEAR ENDED       YEAR ENDED       YEAR ENDED
                                            OCTOBER 31,     DECEMBER 31,     DECEMBER 31,     DECEMBER 31,     DECEMBER 31,
                                                   1992             1992             1993             1994             1995
- ---------------------------------------------------------------------------------------------------------------------------
<S>                                <C>                      <C>              <C>              <C>              <C>
NET ASSET VALUE, BEGINNING OF
   PERIOD                          $              10.00     $     10.11      $      10.22     $      19.00     $      16.30
                                                 ------          ------            ------           ------           ------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (Loss)
   (1)                                               --              --             (0.01)           (0.04)            0.08
  Net Realized and Unrealized
   Gain (Loss) on Investments                      0.11            0.11              8.79            (1.69)           (2.05)
                                                 ------          ------            ------           ------           ------
    Total from Investment
     Operations                                    0.11            0.11              8.78            (1.73)           (1.97)
                                                 ------          ------            ------           ------           ------
DISTRIBUTIONS
  Net Investment income                              --              --                --               --            (0.06)
  Net Realized Gain                                  --              --                --            (0.97)           (1.13)
                                                 ------          ------            ------           ------           ------
    Total Distributions                              --              --                --            (0.97)           (1.19)
                                                 ------          ------            ------           ------           ------
NET ASSET VALUE, END OF PERIOD     $              10.11     $     10.22      $      19.00     $      16.30     $      13.14
                                                 ------          ------            ------           ------           ------
                                                 ------          ------            ------           ------           ------
TOTAL RETURN                                       1.10%           1.09%            85.91%           (9.63)%         (12.77)%
                                                 ------          ------            ------           ------           ------
                                                 ------          ------            ------           ------           ------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period
   (Thousands)                                  $28,806         $74,219          $735,352         $929,638         $876,591
Ratio of Expenses to Average Net
   Assets (1)                                      1.75%**         1.75%**           1.75%            1.75%            1.72%
Ratio of Net Investment Income
   (Loss) to Average Net Assets
   (1)                                            (0.53)%**       (0.33)%**         (0.06)%          (0.26)%           0.60%
Portfolio Turnover Rate                               0%              2%               52%              32%              54%
<FN>
- -----------------
(1) Effect of voluntary expense
limitation
    during the period:
    Per share benefit to net
     investment income             $               0.02     $      0.00      $       0.01              N/A              N/A
  Ratios before expense
   limitation:
    Expenses to Average Net
     Assets                                        4.82%**         2.48%**           1.79%             N/A              N/A
    Net Investment Loss to
     Average Net Assets                           (3.60)%**       (1.06)%**         (0.10)%            N/A              N/A
 *Commencement of operations.
**Annualized
</TABLE>
 
- --------------------------------------------------------------------------------
THE EUROPEAN EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                               PERIOD FROM
                                                            APRIL 2, 1993*
                                                                        TO     YEAR ENDED            YEAR ENDED
                                                              DECEMBER 31,   DECEMBER 31,          DECEMBER 31,
                                                                      1993           1994                  1995
- ---------------------------------------------------------------------------------------------------------------
<S>                                                        <C>               <C>              <C>
NET ASSET VALUE, BEGINNING OF PERIOD                       $        10.00    $      12.91     $           13.94
                                                                   ------          ------                ------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)                                          0.08            0.08                  0.14
  Net Realized and Unrealized Gain on Investments                    2.83            1.29                  1.37
                                                                   ------          ------                ------
    Total from Investment Operations                                 2.91            1.37                  1.51
                                                                   ------          ------                ------
DISTRIBUTIONS
  Net Investment Income                                                --           (0.09)                (0.15)
  Net Realized Gain                                                    --           (0.25)                (1.38)
                                                                   ------          ------                ------
    Total Distributions                                                --           (0.34)                (1.53)
                                                                   ------          ------                ------
NET ASSET VALUE, END OF PERIOD                             $        12.91    $      13.94     $           13.92
                                                                   ------          ------                ------
                                                                   ------          ------                ------
TOTAL RETURN                                                        29.10%          10.88%                11.85%
                                                                   ------          ------                ------
                                                                   ------          ------                ------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)                             $12,681         $27,634               $69,583
Ratio of Expenses to Average Net Assets (1)                          1.00%**         1.00%                 1.00%
Ratio of Net Investment Income to Average Net Assets (1)             1.23%**         0.87%                 1.37%
Portfolio Turnover Rate                                                15%             79%                   13%
<FN>
- -----------------
(1) Effect of voluntary expense limitation during the
   period:
    Per share benefit to net investment income             $         0.09    $       0.06     $            0.03
  Ratios before expense limitation:
    Expenses to Average Net Assets                                   2.43%**         1.62%                 1.25%
    Net Investment Income (Loss) to Average Net Assets              (0.21)%**         0.25%                1.12%
 *Commencement of operations.
**Annualized
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
                                      139
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS
SELECTED PER SHARE DATA AND RATIOS:
- --------------------------------------------------------------------------------
 
THE GLOBAL EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                         PERIOD FROM       TWO MONTHS
                                      JULY 15, 1992*            ENDED       YEAR ENDED       YEAR ENDED       YEAR ENDED
                                      TO OCTOBER 31,     DECEMBER 31,     DECEMBER 31,     DECEMBER 31,     DECEMBER 31,
                                                1992             1992             1993             1994             1995
<S>                                  <C>                <C>              <C>              <C>              <C>
- ------------------------------------------------------------------------------------------------------------------------
NET ASSET VALUE, BEGINNING OF
 PERIOD                              $         10.00    $        9.35    $        9.75    $       13.87    $       13.40
                                             -------            -----    -------------    -------------    -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)                     0.02             0.01             0.08             0.08             0.18
  Net Realized and Unrealized Gain
   (Loss) on Investments                       (0.67)            0.39             4.18             0.79             2.26
                                             -------            -----    -------------    -------------    -------------
    Total from Investment
     Operations                                (0.65)            0.40             4.26             0.87             2.44
                                             -------            -----    -------------    -------------    -------------
DISTRIBUTIONS
  Net Investment Income                           --               --            (0.02)           (0.12)           (0.22)
  In Excess of Net Investment
   Income                                         --               --            (0.03)              --               --
  Net Realized Gain                               --               --            (0.09)           (1.22)           (1.31)
                                             -------            -----    -------------    -------------    -------------
    Total Distributions                           --               --            (0.14)           (1.34)           (1.53)
                                             -------            -----    -------------    -------------    -------------
NET ASSET VALUE, END OF PERIOD       $          9.35    $        9.75    $       13.87    $       13.40    $       14.31
                                             -------            -----    -------------    -------------    -------------
                                             -------            -----    -------------    -------------    -------------
TOTAL RETURN                                   (6.50)%           4.28%           44.24%            6.95%           18.66%
                                             -------            -----    -------------    -------------    -------------
                                             -------            -----    -------------    -------------    -------------
RATIO AND SUPPLEMENTAL DATA:
Net Assets, End of Period
 (Thousands)                                 $11,257          $11,739          $19,918          $78,935          $91,675
Ratio of Expenses to Average Net
 Assets (1)                                     1.00%**          1.00%**          1.00%            1.00%            1.00%
Ratio of Net Investment Income to
 Average Net Assets (1)                         1.00%**          0.69%**          0.84%            0.87%            1.17%
Portfolio Turnover Rate                           10%               5%              42%              12%              28%
<FN>
- -----------------
(1) Effect of voluntary expense
limitation
    during the period:
    Per share benefit to net
     investment income               $          0.08           $ 0.02    $        0.01    $        0.02    $        0.02
  Ratios before expense limitation:
    Expenses to Average Net Assets              5.22%**          2.49%**          1.66%            1.24%            1.13%
    Net Investment Income (Loss) to
     Average Net Assets                        (3.22)%**         (0.80)%**          0.18%          0.63%            1.04%
 *Commencement of operations.
**Annualized
</TABLE>
 
- --------------------------------------------------------------------------------
THE GOLD PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                     PERIOD FROM
                                               FEBRUARY 1, 1994*              YEAR ENDED
                                                 TO DECEMBER 31,            DECEMBER 31,
                                                            1994                    1995
<S>                                       <C>                      <C>
- ----------------------------------------------------------------------------------------
NET ASSET VALUE, BEGINNING OF PERIOD      $                10.00   $                9.13
                                                         -------                 -------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (Loss) (1)                          0.03                   (0.07)
  Net Realized and Unrealized Gain
   (Loss) on Investments                                   (0.88)                   1.22
                                                         -------                 -------
    Total from Investment Operations                       (0.85)                   1.15
                                                         -------                 -------
DISTRIBUTIONS
  Net Investment Income                                    (0.02)                  (0.01)
  Net Realized Gain                                           --                   (1.72)
                                                         -------                 -------
    Total Distributions                                    (0.02)                  (1.73)
                                                         -------                 -------
NET ASSET VALUE, END OF PERIOD                             $9.13                   $8.55
                                                         -------                 -------
                                                         -------                 -------
TOTAL RETURN                                               (8.49)%                 13.21%
                                                         -------                 -------
                                                         -------                 -------
RATIO AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)                    $30,243                  $7,409
Ratio of Expenses to Average Net Assets
 (1)                                                        1.25%**                  1.25%
Ratio of Net Investment Income (Loss) to
 Average Net Assets (1)                                     0.41%**                 (0.31)%
Portfolio Turnover Rate                                       56%                     47%
<FN>
- -----------------
(1) Effect of voluntary expense
 limitation during the period:
    Per share benefit to net investment
     income                               $                 0.04   $                0.11
  Ratios before expense limitation:
    Expenses to Average Net Assets                          1.72%**                  1.76%
    Net Investment Loss to Average Net
     Assets                                                (0.06)%**                 (0.82)%
 *Commencement of operations.
**Annualized
</TABLE>
 
   The accompanying notes are an integral part of these financial statements.
 
- --------------------------------------------------------------------------------
 
                                      140
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS
SELECTED PER SHARE DATA AND RATIOS:
- --------------------------------------------------------------------------------
 
THE INTERNATIONAL EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                  TWO MONTHS
                                                                       ENDED   YEAR ENDED   YEAR ENDED   YEAR ENDED
                                      YEAR ENDED    YEAR ENDED      DECEMBER     DECEMBER     DECEMBER     DECEMBER
                                     OCTOBER 31,   OCTOBER 31,           31,          31,          31,          31,
                                            1991          1992          1992         1993         1994         1995
<S>                                  <C>           <C>           <C>           <C>          <C>          <C>
- -------------------------------------------------------------------------------------------------------------------
NET ASSET VALUE, BEGINNING OF
 PERIOD                              $     10.05   $     10.52   $     9.83    $     9.98   $    14.09   $    15.34
                                     -----------   -----------   -----------   ----------   ----------   ----------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)                 0.12          0.12         0.01          0.15         0.16         0.16
  Net Realized and Unrealized Gain
   (Loss) on Investments                    0.58         (0.59)        0.14          4.36         1.54         1.55
                                     -----------   -----------   -----------   ----------   ----------   ----------
    Total from Investment
     Operations                             0.70         (0.47)        0.15          4.51         1.70         1.71
                                     -----------   -----------   -----------   ----------   ----------   ----------
DISTRIBUTIONS
  Net Investment Income                    (0.15)        (0.17)          --         (0.01)       (0.18)       (0.06)
  In Excess of Net Investment
   Income                                     --            --           --         (0.13)          --           --
  Net Realized Gain                        (0.08)        (0.05)          --         (0.26)       (0.27)       (1.84)
                                     -----------   -----------   -----------   ----------   ----------   ----------
    Total Distributions                    (0.23)        (0.22)          --         (0.40)       (0.45)       (1.90)
                                     -----------   -----------   -----------   ----------   ----------   ----------
NET ASSET VALUE, END OF PERIOD       $     10.52   $      9.83   $     9.98    $    14.09   $    15.34   $    15.15
                                     -----------   -----------   -----------   ----------   ----------   ----------
                                     -----------   -----------   -----------   ----------   ----------   ----------
TOTAL RETURN                                7.17%        (4.56)%       1.53%        46.50%       12.39%       11.77%
                                     -----------   -----------   -----------   ----------   ----------   ----------
                                     -----------   -----------   -----------   ----------   ----------   ----------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period
 (Thousands)                            $283,776      $486,836     $510,727      $947,045   $1,304,770   $1,598,530
Ratio of Expenses to Average Net
 Assets (1)                                 1.00%         1.00%        1.00%**       1.00%        1.00%        1.00%
Ratio of Net Investment Income to
 Average Net Assets (1)                     2.27%         1.46%        0.68%**       1.25%        1.12%        1.38%
Portfolio Turnover Rate                       22%           12%           5%           23%          16%          27%
<FN>
- -----------------
(1) Effect of voluntary expense
limitation
    during the period:
    Per share benefit to net
     investment income               $      0.01   $      0.00   $     0.00    $     0.01       $0.004       $0.003
  Ratios before expense limitation:
    Expenses to Average Net Assets          1.09%         1.02%        1.14%**       1.06%        1.03%        1.03%
    Net Investment Income to
     Average Net Assets                     2.18%         1.44%        0.54%**       1.19%        1.09%        1.35%
**Annualized
</TABLE>
 
- --------------------------------------------------------------------------------
THE INTERNATIONAL SMALL CAP PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                              PERIOD FROM
                                       DECEMBER 15, 1992*         YEAR ENDED         YEAR ENDED               YEAR ENDED
                                          TO DECEMBER 31,       DECEMBER 31,       DECEMBER 31,             DECEMBER 31,
                                                     1992             1993++               1994                     1995
- ------------------------------------------------------------------------------------------------------------------------
<S>                                  <C>                      <C>                <C>                <C>
NET ASSET VALUE, BEGINNING OF
 PERIOD                              $              10.00     $        10.09     $        14.64     $              15.15
                                                   ------             ------             ------                   ------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)                          0.01               0.09               0.14                     0.24
  Net Realized and Unrealized Gain
   on Investments (2)                                0.08               4.48               0.62                     0.15
                                                   ------             ------             ------                   ------
    Total from Investment
     Operations                                      0.09               4.57               0.76                     0.39
                                                   ------             ------             ------                   ------
DISTRIBUTIONS
  Net Investment Income                                --               0.00              (0.03)                   (0.23)
  In Excess of Net Investment
   Income                                              --              (0.02)                --                       --
  Net Realized Gain                                    --                 --              (0.22)                   (0.37)
                                                   ------             ------             ------                   ------
    Total Distributions                                --              (0.02)             (0.25)                   (0.60)
                                                   ------             ------             ------                   ------
NET ASSET VALUE, END OF PERIOD       $              10.09     $        14.64     $        15.15     $              14.94
                                                   ------             ------             ------                   ------
                                                   ------             ------             ------                   ------
TOTAL RETURN                                         0.90%             45.34%              5.25%                    2.60%
                                                   ------             ------             ------                   ------
                                                   ------             ------             ------                   ------
RATIO AND SUPPLEMENTAL DATA:
Net Assets, End of Period
 (Thousands)                                       $3,824            $52,834           $160,101                 $198,669
Ratio of Expenses to Average Net
 Assets (1)                                          1.15%**            1.15%              1.15%                    1.15%
Ratio of Net Investment Income to
 Average Net Assets (1)                              1.37%**            0.66%              1.18%                    1.72%
Portfolio Turnover Rate                                 0%                14%                 8%                      24%
<FN>
- -----------------
(1) Effect of voluntary expense
 limitation during the period:
    Per share benefit to net
     investment income               $               0.16     $         0.10     $         0.02     $               0.01
  Ratios before expense limitation:
    Expenses to Average Net Assets                  21.67%**            1.86%              1.29%                    1.24%
    Net Investment Income (Loss) to
     Average Net Assets                            (19.15)%**          (0.05)%             1.04%                    1.63%
(2) Includes a 1% transaction fee on purchases and redemptions of capital shares.
++Per share amounts for the year ended December 31, 1993 are based on average outstanding
  shares.
 *Commencement of operations.
**Annualized
</TABLE>
 
   The accompanying notes are an integral part of these financial statements.
 
- --------------------------------------------------------------------------------
 
                                      141
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS
SELECTED PER SHARE DATA AND RATIOS:
- --------------------------------------------------------------------------------
 
THE JAPANESE EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                                       PERIOD FROM
                                                                                   APRIL 25, 1994*         YEAR ENDED
                                                                                   TO DECEMBER 31,       DECEMBER 31,
                                                                                              1994               1995
<S>                                                                               <C>                <C>
- ---------------------------------------------------------------------------------------------------------------------
NET ASSET VALUE, BEGINNING OF PERIOD                                              $          10.00   $           9.83
                                                                                            ------             ------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (Loss) (1)                                                           (0.01)              0.04
  Net Realized and Unrealized Loss on Investments++                                          (0.16)             (0.40)
                                                                                            ------             ------
    Total from Investment Operations                                                         (0.17)             (0.36)
                                                                                            ------             ------
DISTRIBUTIONS
  In Excess of Net Investment Income                                                            --              (0.20)
                                                                                            ------             ------
NET ASSET VALUE, END OF PERIOD                                                    $           9.83   $           9.27
                                                                                            ------             ------
                                                                                            ------             ------
TOTAL RETURN                                                                                 (1.70)%            (3.64)%
                                                                                            ------             ------
                                                                                            ------             ------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)                                                      $50,332           $119,278
Ratio of Expenses to Average Net Assets (1)                                                   1.00%**             1.00%
Ratio of Net Investment Income (Loss) to Average Net Assets (1)                              (0.10)%**             0.15%
Portfolio Turnover Rate                                                                          1%                52%
<FN>
- ---------------
(1) Effect of voluntary expense limitation during the period:
    Per share benefit to net investment income                                    $           0.02   $           0.06
  Ratios before expense limitation:
    Expenses to Average Net Assets                                                            1.27%**             1.20%
    Net Investment Loss to Average Net Assets                                                (0.37)%**            (0.05)%
 *Commencement of operations.
**Annualized
++The amount shown for the year ended December 31, 1995 for a share outstanding
  throughout the year does not accord with aggregate net gains on investments
  for the year because of the timing of sales and repurchases of the Portfolio
  shares in relation to fluctuating market value of the investments in the
  Portfolio.
</TABLE>
 
- --------------------------------------------------------------------------------
THE LATIN AMERICAN PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                                                            PERIOD FROM
                                                                                                            JANUARY 18,
                                                                                                                  1995*
                                                                                                        TO DECEMBER 31,
                                                                                                                   1995
<S>                                                                                                    <C>
- -----------------------------------------------------------------------------------------------------------------------
NET ASSET VALUE, BEGINNING OF PERIOD                                                                   $          10.00
                                                                                                                 ------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)                                                                                        0.05
  Net Realized and Unrealized Loss on Investments                                                                 (0.92)
                                                                                                                 ------
    Total from Investment Operations                                                                              (0.87)
                                                                                                                 ------
DISTRIBUTIONS
  Net Investment Income                                                                                           (0.04)
  Return of Capital                                                                                               (0.03)
                                                                                                                 ------
    Total Distributions                                                                                           (0.07)
                                                                                                                 ------
NET ASSET VALUE, END OF PERIOD                                                                         $           9.06
                                                                                                                 ------
                                                                                                                 ------
TOTAL RETURN                                                                                                      (8.68)%
                                                                                                                 ------
                                                                                                                 ------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)                                                                           $15,376
Ratio of Expenses to Average Net Assets (1)                                                                        1.70%**
Ratio of Net Investment Income to Average Net Assets (1)                                                           0.62%**
Portfolio Turnover Rate                                                                                             137%
<FN>
- ---------------
(1) Effect of voluntary expense limitation during the period:
    Per share benefit to net investment income                                                         $           0.09
  Ratios before expense limitation:
    Expenses to Average Net Assets                                                                                 3.13%**
    Net Investment Loss to Average Net Assets                                                                     (0.48)%**
  *Commencement of operations.
 **Annualized
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
                                      142
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS
SELECTED PER SHARE DATA AND RATIOS:
- --------------------------------------------------------------------------------
 
THE AGGRESSIVE EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                         PERIOD FROM
                                                      MARCH 8, 1995*
                                                                  TO
                                                        DECEMBER 31,
                                                                1995
<S>                                                 <C>
- --------------------------------------------------------------------
NET ASSET VALUE, BEGINNING OF PERIOD                $          10.00
                                                              ------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)                                     0.15
  Net Realized and Unrealized Gain on Investments               3.95
                                                              ------
    Total from Investment Operations                            4.10
                                                              ------
DISTRIBUTIONS
  Net Investment Income                                        (0.15)
  Net Realized Gain                                            (1.78)
                                                              ------
    Total Distributions                                        (1.93)
                                                              ------
NET ASSET VALUE, END OF PERIOD                      $          12.17
                                                              ------
                                                              ------
TOTAL RETURN                                                   41.25%
                                                              ------
                                                              ------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)                        $28,548
Ratio of Expenses to Average Net Assets (1)                     1.00%**
Ratio of Net Investment Income to Average Net
 Assets (1)                                                     1.64%**
Portfolio Turnover Rate                                          309%
<FN>
- ---------------
(1) Effect of voluntary expense limitation during
   the period:
    Per share benefit to net investment income      $           0.06
  Ratios before expense limitation:
    Expenses to Average Net Assets                              1.59%**
    Net Investment Income to Average Net Assets                 1.05%**
 *Commencement of operations.
**Annualized
</TABLE>
 
- --------------------------------------------------------------------------------
THE EMERGING GROWTH PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                            TWO MONTHS
                             YEAR ENDED     YEAR ENDED           ENDED      YEAR ENDED     YEAR ENDED     YEAR ENDED
                            OCTOBER 31,    OCTOBER 31,    DECEMBER 31,    DECEMBER 31,   DECEMBER 31,   DECEMBER 31,
                                 1991++           1992            1992            1993           1994           1995
<S>                        <C>            <C>             <C>             <C>            <C>            <C>
- --------------------------------------------------------------------------------------------------------------------
NET ASSET VALUE,
 BEGINNING OF PERIOD       $       9.03   $      16.18    $      14.97    $      16.22   $      16.22   $      16.12
                                 ------         ------          ------          ------         ------         ------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment Loss (1)            --          (0.09)          (0.01)          (0.11)         (0.09)         (0.18)
  Net Realized and
   Unrealized Gain (Loss)
   on Investments                  7.19          (1.12)           1.26            0.11          (0.01)          5.55
                                 ------         ------          ------          ------         ------         ------
    Total from Investment
     Operations                    7.19          (1.21)           1.25            0.00          (0.10)          5.37
                                 ------         ------          ------          ------         ------         ------
DISTRIBUTIONS
  Net Investment Income           (0.04)            --              --              --             --             --
                                 ------         ------          ------          ------         ------         ------
NET ASSET VALUE, END OF
 PERIOD                    $      16.18   $      14.97    $      16.22    $      16.22   $      16.12   $      21.49
                                 ------         ------          ------          ------         ------         ------
                                 ------         ------          ------          ------         ------         ------
TOTAL RETURN                      79.84%         (7.48)%          8.35%           0.00%         (0.62)%        33.31%
                                 ------         ------          ------          ------         ------         ------
                                 ------         ------          ------          ------         ------         ------
RATIOS AND SUPPLEMENTAL
 DATA:
Net Assets, End of Period
 (Thousands)                    $54,364        $80,156         $94,161        $103,621       $117,669       $119,378
Ratio of Expenses to
 Average Net Assets (1)            1.25%          1.25%           1.25%**         1.25%          1.25%          1.25%
Ratio of Net Investment
 Loss to
 Average Net Assets (1)            0.00%         (0.66)%         (0.68)%**        (0.77)%        (0.61)%        (0.76)%
Portfolio Turnover Rate               2%            17%              1%             25%            24%            25%
<FN>
- ---------------
(1) Effect of voluntary
   expense limitation
   during the period:
    Per share benefit to
     net investment loss   $       0.02   $       0.01    $       0.00    $       0.01   $      0.002   $      0.003
  Ratios before expense
   limitation:
    Expenses to Average
     Net Assets                    1.39%          1.29%           1.36%**         1.31%          1.26%          1.26%
    Net Investment Loss
     to Average Net
     Assets                       (0.14)%        (0.71)%         (0.79)%**        (0.83)%        (0.62)%        (0.77)%
++Per share amounts for the year ended October 31, 1991 are based on average
  outstanding shares.
**Annualized
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
                                      143
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS
SELECTED PER SHARE DATA AND RATIOS:
- --------------------------------------------------------------------------------
 
THE EQUITY GROWTH PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                     PERIOD FROM
                                        APRIL 2,
                                           1991*                   TWO MONTHS                                  YEAR ENDED
                                      TO OCTOBER    YEAR ENDED          ENDED     YEAR ENDED     YEAR ENDED      DECEMBER
                                             31,   OCTOBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,           31,
                                            1991          1992           1992           1993           1994          1995
- -------------------------------------------------------------------------------------------------------------------------
<S>                                  <C>           <C>           <C>            <C>            <C>            <C>
NET ASSET VALUE, BEGINNING OF
 PERIOD                              $     10.00   $     10.66   $      11.44   $      11.88   $      12.14   $     12.02
                                     -----------   -----------         ------         ------         ------   -----------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)                 0.05          0.16           0.03           0.22           0.17          0.22
  Net Realized and Unrealized Gain
   on Investments                           0.61          0.82           0.41           0.28           0.21          4.93
                                     -----------   -----------         ------         ------         ------   -----------
    Total from Investment
     Operations                             0.66          0.98           0.44           0.50           0.38          5.15
                                     -----------   -----------         ------         ------         ------   -----------
DISTRIBUTIONS
  Net Investment Income                       --         (0.20)            --          (0.23)         (0.13)        (0.28)
  In Excess of Net Investment
   Income                                     --            --             --          (0.01)            --            --
  Net Realized Gain                           --            --             --             --          (0.37)        (2.75)
                                     -----------   -----------         ------         ------         ------   -----------
    Total Distributions                       --         (0.20)            --          (0.24)         (0.50)        (3.03)
                                     -----------   -----------         ------         ------         ------   -----------
NET ASSET VALUE, END OF PERIOD       $     10.66   $     11.44   $      11.88   $      12.14   $      12.02   $     14.14
                                     -----------   -----------         ------         ------         ------   -----------
                                     -----------   -----------         ------         ------         ------   -----------
TOTAL RETURN                                6.60%         9.26%          3.85%          4.33%          3.26%        45.02%
                                     -----------   -----------         ------         ------         ------   -----------
                                     -----------   -----------         ------         ------         ------   -----------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period
 (Thousands)                             $18,139       $36,558        $45,985        $73,789        $97,259      $158,112
Ratio of Expenses to Average Net
 Assets (1)                                 0.80%**        0.80%         0.80%**         0.80%         0.80%         0.80%
Ratio of Net Investment Income to
 Average Net Assets (1)                     2.34%**        1.73%         1.93%**         1.59%         1.44%         1.57%
Portfolio Turnover Rate                        3%           38%             1%           172%           146%          186%
<FN>
- ---------------
(1) Effect of voluntary expense
    limitation during the period:
    Per share benefit to net
  investment
      income                         $      0.03   $      0.02   $       0.01   $       0.02   $       0.01   $      0.01
  Ratios before expense limitation:
    Expenses to Average Net Assets          1.37%**        1.01%         1.11%**         0.93%         0.89%         0.88%
    Net Investment Income to
  Average
      Net Assets                            1.77%**        1.52%         1.62%**         1.46%         1.35%         1.49%
 *Commencement of operations.
 **Annualized
</TABLE>
 
- --------------------------------------------------------------------------------
THE SMALL CAP VALUE EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                    PERIOD FROM
                                                   DECEMBER 17,
                                                          1992*
                                                    TO DECEMBER     YEAR ENDED     YEAR ENDED     YEAR ENDED
                                                            31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,
                                                           1992           1993           1994           1995
- ------------------------------------------------------------------------------------------------------------
<S>                                                <C>            <C>            <C>            <C>
NET ASSET VALUE, BEGINNING OF PERIOD               $      10.00   $      10.14   $      11.10   $      10.80
                                                         ------         ------         ------         ------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)                                0.01           0.24           0.28           0.30
  Net Realized and Unrealized Gain (Loss) on
   Investments                                             0.13           0.90          (0.01)          1.82
                                                         ------         ------         ------         ------
    Total from Investment Operations                       0.14           1.14           0.27           2.12
                                                         ------         ------         ------         ------
DISTRIBUTIONS
  Net Investment Income                                      --          (0.18)         (0.27)         (0.38)
  Net Realized Gain                                          --             --          (0.30)         (0.63)
                                                         ------         ------         ------         ------
    Total Distributions                                      --          (0.18)         (0.57)         (1.01)
                                                         ------         ------         ------         ------
NET ASSET VALUE, END OF PERIOD                     $      10.14   $      11.10   $      10.80   $      11.91
                                                         ------         ------         ------         ------
                                                         ------         ------         ------         ------
TOTAL RETURN                                               1.40%         11.33%          2.53%         20.63%
                                                         ------         ------         ------         ------
                                                         ------         ------         ------         ------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)                    $5,974        $26,775        $40,033        $51,919
Ratio of Expenses to Average Net Assets (1)                1.00%**         1.00%         1.00%          1.00%
Ratio of Net Investment Income to Average Net
 Assets (1)                                                1.64%**         2.56%         2.67%          2.60%
Portfolio Turnover Rate                                       0%            29%            22%            36%
<FN>
- ---------------
(1) Effect of voluntary expense limitation during
 the period:
    Per share benefit to net investment income     $       0.13   $       0.06   $       0.03   $       0.02
  Ratios before expense limitation:
    Expenses to Average Net Assets                        23.14%**         1.68%         1.26%          1.21%
    Net Investment Income (Loss) to Average Net
   Assets                                                (20.50)%**         1.88%         2.41%         2.39%
 *Commencement of operations.
 **Annualized
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
                                      144
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS
SELECTED PER SHARE DATA AND RATIOS:
- --------------------------------------------------------------------------------
 
THE U.S. REAL ESTATE PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                             PERIOD FROM
                                                      FEBRUARY 24, 1995*
                                                    TO DECEMBER 31, 1995
- ------------------------------------------------------------------------
<S>                                                 <C>
NET ASSET VALUE, BEGINNING OF PERIOD                $              10.00
                                                                  ------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)                                         0.26
  Net Realized and Unrealized Gain on Investments                   1.84
                                                                  ------
    Total from Investment Operations                                2.10
                                                                  ------
DISTRIBUTIONS
  Net Investment Income                                            (0.24)
  Net Realized Gain                                                (0.44)
                                                                  ------
    Total Distributions                                            (0.68)
                                                                  ------
NET ASSETS, END OF PERIOD                                         $11.42
                                                                  ------
                                                                  ------
TOTAL RETURN                                                       21.07%
                                                                  ------
                                                                  ------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)                            $69,509
Ratio of Expenses to Average Net Assets (1)                         1.00%**
Ratio of Net Investment Income to Average Net
 Assets (1)                                                         4.04%**
Portfolio Turnover Rate                                              158%
<FN>
- ---------------
(1) Effect of voluntary expense limitation during
 the period:
    Per share benefit to net investment income      $               0.02
  Ratios before expense limitation:
    Expenses to Average Net Assets                                  1.33%**
    Net Investment Income to Average Net Assets                     3.71%**
 *Commencement of operations.
**Annualized
</TABLE>
 
- --------------------------------------------------------------------------------
THE VALUE EQUITY PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                          TWO MONTHS
                            YEAR ENDED     YEAR ENDED          ENDED     YEAR ENDED     YEAR ENDED     YEAR ENDED
                           OCTOBER 31,    OCTOBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,
                                  1991           1992           1992           1993           1994           1995
<S>                       <C>            <C>            <C>            <C>            <C>            <C>
- -----------------------------------------------------------------------------------------------------------------
NET ASSET VALUE,
 BEGINNING OF PERIOD      $      8.59    $      10.24   $      10.71   $      11.31   $      12.63   $      11.50
                               ------          ------         ------         ------         ------         ------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment Income
   (1)                           0.46            0.38           0.08           0.37           0.40           0.38
  Net Realized and
   Unrealized Gain (Loss)
   on Investments                1.67            0.48           0.52           1.31          (0.55)          3.30
                               ------          ------         ------         ------         ------         ------
    Total from Investment
     Operations                  2.13            0.86           0.60           1.68          (0.15)          3.68
                               ------          ------         ------         ------         ------         ------
DISTRIBUTIONS
  Net Investment Income         (0.48)          (0.39)            --          (0.36)         (0.40)         (0.47)
  Net Realized Gain                --              --             --             --          (0.58)         (0.77)
                               ------          ------         ------         ------         ------         ------
    Total Distributions         (0.48)          (0.39)            --          (0.36)         (0.98)         (1.24)
                               ------          ------         ------         ------         ------         ------
NET ASSET VALUE, END OF
 PERIOD                   $     10.24    $      10.71   $      11.31   $      12.63   $      11.50   $      13.94
                               ------          ------         ------         ------         ------         ------
                               ------          ------         ------         ------         ------         ------
TOTAL RETURN                    25.34%           8.51%          5.60%         15.14%         (1.29)%        33.69%
                               ------          ------         ------         ------         ------         ------
                               ------          ------         ------         ------         ------         ------
RATIOS AND SUPPLEMENTAL
 DATA:
Net Assets, End of Period
 (Thousands)                  $16,304         $25,013        $27,541        $54,598        $73,406       $147,365
Ratio of Expenses to
 Average Net Assets (1)          0.70%           0.70%          0.70%**         0.70%         0.70%          0.70%
Ratio of Net Investment
 Income to Average Net
 Assets (1)                      4.57%           3.72%          4.41%**         3.23%         3.37%          3.01%
Portfolio Turnover Rate            90%             56%             9%            51%            33%            43%
<FN>
- ---------------
(1) Effect of voluntary
expense
    limitation during the
period:
    Per share benefit to
    net investment income $      0.02    $       0.01   $       0.01   $       0.03   $       0.01   $       0.01
  Ratios before expense
 limitation:
    Expenses to Average
   Net Assets                    0.87%           0.84%          1.20%**         0.95%         0.80%          0.77%
    Net Investment Income
  to
      Average Net Assets         4.40%           3.58%          3.91%**         2.98%         3.27%          2.94%
 **Annualized
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
                                      145
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS
SELECTED PER SHARE DATA AND RATIOS:
- --------------------------------------------------------------------------------
 
THE BALANCED PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                         TWO MONTHS
                             YEAR ENDED    YEAR ENDED         ENDED     YEAR ENDED     YEAR ENDED     YEAR ENDED
                            OCTOBER 31,   OCTOBER 31,      DECEMBER   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,
                                   1991          1992      31, 1992           1993           1994           1995
<S>                        <C>            <C>           <C>           <C>            <C>            <C>
- ----------------------------------------------------------------------------------------------------------------
NET ASSET VALUE,
 BEGINNING OF PERIOD       $       9.62   $     10.61   $     11.00   $      11.31   $      11.13   $       8.96
                                 ------   -----------   -----------         ------         ------         ------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment Income
   (1)                             0.59          0.58          0.10           0.44           0.42           0.39
  Net Realized and
   Unrealized Gain (Loss)
   on Investments                  1.03          0.42          0.21           0.79          (0.64)          1.62
                                 ------   -----------   -----------         ------         ------         ------
    Total from Investment
     Operations                    1.62          1.00          0.31           1.23          (0.22)          2.01
                                 ------   -----------   -----------         ------         ------         ------
DISTRIBUTIONS
  Net Investment Income           (0.63)        (0.58)           --          (0.41)         (0.49)         (0.50)
  In Excess of Net
   Investment Income                 --            --            --          (0.08)            --             --
  Net Realized Gain                  --         (0.03)           --          (0.06)         (1.46)         (0.49)
  In Excess of Net
   Realized Gain                     --            --            --          (0.86)            --             --
                                 ------   -----------   -----------         ------         ------         ------
    Total Distributions           (0.63)        (0.61)           --          (1.41)         (1.95)         (0.99)
                                 ------   -----------   -----------         ------         ------         ------
NET ASSET VALUE, END OF
 PERIOD                    $      10.61   $     11.00   $     11.31   $      11.13   $       8.96   $       9.98
                                 ------   -----------   -----------         ------         ------         ------
                                 ------   -----------   -----------         ------         ------         ------
TOTAL RETURN                      17.31%         9.57%         2.82%         12.09%         (2.32)%        23.63%
                                 ------   -----------   -----------         ------         ------         ------
                                 ------   -----------   -----------         ------         ------         ------
RATIOS AND SUPPLEMENTAL
 DATA:
Net Assets, End of Period
 (Thousands)                    $51,334       $40,332       $39,984        $29,684        $18,492        $22,642
Ratio of Expenses to
 Average Net Assets (1)            0.70%         0.70%         0.70%**         0.70%         0.70%          0.70%
Ratio of Net Investment
 Income to Average
 Net Assets (1)                    5.99%         5.21%         5.29%**         3.88%         4.13%          4.10%
Portfolio Turnover Rate              67%           40%            4%           136%            44%            26%
<FN>
- ---------------
(1) Effect of voluntary
expense limitation
    during the period:
    Per share benefit to
     net investment
     income                $       0.01   $      0.01   $      0.01   $       0.04   $       0.03   $       0.03
  Ratios before expense
 limitation:
    Expenses to Average
     Net Assets                    0.78%         0.79%         1.00%**         1.02%         0.95%          1.02%
    Net Investment Income
     to Average Net
     Assets                        5.91%         5.12%         4.99%**         3.56%         3.88%          3.78%
 **Annualized
</TABLE>
 
- --------------------------------------------------------------------------------
THE EMERGING MARKETS DEBT PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                                                        PERIOD FROM
                                                                                        FEBRUARY 1,
                                                                                              1994*         YEAR ENDED
                                                                                    TO DECEMBER 31,       DECEMBER 31,
                                                                                               1994               1995
<S>                                                                                <C>                <C>
- ----------------------------------------------------------------------------------------------------------------------
NET ASSET VALUE, BEGINNING OF PERIOD                                               $          10.00   $           8.59
                                                                                             ------             ------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income                                                                        0.50               1.36
  Net Realized and Unrealized Gain (Loss) on Investments                                      (1.91)              0.91
                                                                                             ------             ------
    Total from Investment Operations                                                          (1.41)              2.27
                                                                                             ------             ------
DISTRIBUTIONS
  Net Investment Income                                                                          --              (1.86)
  Net Realized Gain                                                                              --              (0.41)
                                                                                             ------             ------
    Total Distributions                                                                          --              (2.27)
                                                                                             ------             ------
NET ASSET VALUE, END OF PERIOD                                                     $           8.59   $           8.59
                                                                                             ------             ------
                                                                                             ------             ------
TOTAL RETURN                                                                                 (14.10)%            28.23%
                                                                                             ------             ------
                                                                                             ------             ------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)                                                      $144,949           $181,878
Ratio of Expenses to Average Net Assets                                                        1.49%**             1.75%
Ratio of Net Investment Income to Average Net Assets                                           9.97%**            14.70%
Portfolio Turnover Rate                                                                         273%               406%
<FN>
- ---------------
 *Commencement of operations.
**Annualized
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
                                      146
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS
SELECTED PER SHARE DATA AND RATIOS:
- --------------------------------------------------------------------------------
 
THE FIXED INCOME PORTFOLIO
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                      PERIOD FROM
                                          MAY 15,                    TWO MONTHS
                                            1991*     YEAR ENDED          ENDED     YEAR ENDED     YEAR ENDED     YEAR ENDED
                                       TO OCTOBER    OCTOBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,
                                         31, 1991           1992           1992           1993           1994           1995
<S>                                  <C>            <C>            <C>            <C>            <C>            <C>
- ----------------------------------------------------------------------------------------------------------------------------
NET ASSET VALUE, BEGINNING OF
 PERIOD                              $     10.00    $      10.55   $      10.92   $      10.93   $      11.05   $       9.82
                                          ------          ------         ------         ------         ------         ------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)                 0.22            0.69           0.10           0.54           0.59           0.72
  Net Realized and Unrealized Gain
    (Loss) on Investments                   0.49            0.39           0.01           0.41          (0.92)          1.06
                                          ------          ------         ------         ------         ------         ------
    Total from Investment
     Operations                             0.71            1.08           0.11           0.95          (0.33)          1.78
                                          ------          ------         ------         ------         ------         ------
DISTRIBUTIONS
  Net Investment Income                    (0.16)          (0.69)         (0.10)         (0.56)         (0.53)         (0.79)
  In Excess of Net Investment
   Income                                     --              --             --          (0.01)            --             --
  Net Realized Gain                           --           (0.02)            --          (0.26)         (0.37)            --
  In Excess of Net Realized Gain              --              --             --             --          (0.00)+           --
                                          ------          ------         ------         ------         ------         ------
    Total Distributions                    (0.16)          (0.71)         (0.10)         (0.83)         (0.90)         (0.79)
                                          ------          ------         ------         ------         ------         ------
NET ASSET VALUE, END OF PERIOD       $     10.55    $      10.92   $      10.93   $      11.05   $       9.82   $      10.81
                                          ------          ------         ------         ------         ------         ------
                                          ------          ------         ------         ------         ------         ------
TOTAL RETURN                                7.12%          10.61%          1.02%          9.07%         (3.10)%        18.76%
                                          ------          ------         ------         ------         ------         ------
                                          ------          ------         ------         ------         ------         ------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period
 (Thousands)                             $72,326        $146,546       $154,210       $240,668       $209,331       $165,527
Ratio of Expenses to Average Net
 Assets (1)                                 0.45%**         0.45%          0.45%**         0.45%         0.45%          0.45%
Ratio of Net Investment Income to
 Average Net Assets (1)                     7.29%**         6.59%          5.56%**         4.97%         5.73%          6.85%
Portfolio Turnover Rate                       48%            105%            15%           240%           388%           172%
<FN>
- ---------------
(1) Effect of voluntary expense
limitation
    during the period:
    Per share benefit to net
     investment income               $      0.01    $       0.02   $       0.01   $       0.02   $       0.01   $       0.01
  Ratios before expense limitation:
    Expenses to Average Net Assets          0.81%**         0.59%          0.75%**         0.60%         0.58%          0.59%
    Net Investment Income to
     Average Net Assets                     6.93%**         6.45%          5.26%**         4.82%         5.60%          6.71%
 *Commencement of operations.
 **Annualized
 +Amount is less than $0.01 per
 share
</TABLE>
 
- --------------------------------------------------------------------------------
THE GLOBAL FIXED INCOME PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                      PERIOD FROM
                                     MAY 1, 1991*                    TWO MONTHS
                                       TO OCTOBER     YEAR ENDED          ENDED     YEAR ENDED     YEAR ENDED     YEAR ENDED
                                              31,    OCTOBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,
                                             1991           1992           1992           1993           1994           1995
<S>                                  <C>            <C>            <C>            <C>            <C>            <C>
- ----------------------------------------------------------------------------------------------------------------------------
NET ASSET VALUE, BEGINNING OF
 PERIOD                              $      10.00   $      10.61   $      11.41   $      11.26   $      11.68   $      10.29
                                           ------         ------         ------         ------         ------         ------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)                  0.16           0.53           0.14           0.69           0.70           0.76
  Net Realized and Unrealized Gain
   (Loss) on Investments                     0.45           0.55          (0.29)          0.90          (1.38)          1.15
                                           ------         ------         ------         ------         ------         ------
    Total from Investment
     Operations                              0.61           1.08          (0.15)          1.59          (0.68)          1.91
                                           ------         ------         ------         ------         ------         ------
DISTRIBUTIONS
  Net Investment Income                        --          (0.27)            --          (0.79)         (0.40)         (0.98)
  In Excess of Net Investment
   Income                                      --             --             --          (0.22)            --             --
  Net Realized Gain                            --          (0.01)            --          (0.16)         (0.31)            --
                                           ------         ------         ------         ------         ------         ------
    Total Distributions                        --          (0.28)            --          (1.17)         (0.71)         (0.98)
                                           ------         ------         ------         ------         ------         ------
NET ASSET VALUE, END OF PERIOD       $      10.61   $      11.41   $      11.26   $      11.68   $      10.29   $      11.22
                                           ------         ------         ------         ------         ------         ------
                                           ------         ------         ------         ------         ------         ------
TOTAL RETURN                                 6.10%         10.29%         (1.31)%        15.34%         (6.08)%        19.32%
                                           ------         ------         ------         ------         ------         ------
                                           ------         ------         ------         ------         ------         ------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period
 (Thousands)                              $28,236        $94,847        $92,897       $172,468       $130,675       $102,852
Ratio of Expenses to Average Net
 Assets (1)                                  0.50%**         0.50%         0.50%**         0.50%         0.50%          0.50%
Ratio of Net Investment Income to
 Average Net Assets (1)                      7.24%**         6.92%         6.99%**         5.99%         6.34%          6.79%
Portfolio Turnover Rate                        20%           144%             9%           108%           171%           207%
<FN>
- ---------------
(1) Effect of voluntary expense
limitation
    during the period:
    Per share benefit to net
     investment income               $       0.02   $       0.03   $       0.01   $       0.02   $       0.02   $       0.02
  Ratios before expense limitation:
    Expenses to Average Net Assets           1.62%**         0.86%         0.90%**         0.70%         0.66%          0.71%
    Net Investment Income to
     Average Net Assets                      6.12%**         6.56%         6.59%**         5.79%         6.18%          6.58%
 *Commencement of operations.
 **Annualized
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
                                      147
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS
SELECTED PER SHARE DATA AND RATIOS:
- --------------------------------------------------------------------------------
 
THE HIGH YIELD PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                         PERIOD FROM    TWO MONTHS ENDED      YEAR ENDED      YEAR ENDED          YEAR ENDED
                                 SEPTEMBER 28, 1992*        DECEMBER 31,    DECEMBER 31,    DECEMBER 31,        DECEMBER 31,
                                 TO OCTOBER 31, 1992                1992            1993            1994                1995
- ----------------------------------------------------------------------------------------------------------------------------
<S>                             <C>                     <C>                 <C>             <C>             <C>
NET ASSET VALUE, BEGINNING OF
 PERIOD                         $              10.00    $           9.77    $       9.95    $      11.16    $           9.55
                                             -------              ------    ------------    ------------             -------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment Income (1)                     0.08                0.14            0.90            0.97                1.14
  Net Realized and Unrealized
   Gain (Loss)
   on Investments                              (0.31)               0.19            1.21           (1.40)               0.97
                                             -------              ------    ------------    ------------             -------
    Total from Investment
     Operations                                (0.23)               0.33            2.11           (0.43)               2.11
                                             -------              ------    ------------    ------------             -------
DISTRIBUTIONS
  Net Investment Income                           --               (0.15)          (0.90)          (0.97)              (1.20)
  Net Realized Gain                               --                  --              --           (0.21)                 --
                                             -------              ------    ------------    ------------             -------
    Total Distributions                           --               (0.15)          (0.90)          (1.18)              (1.20)
                                             -------              ------    ------------    ------------             -------
NET ASSET VALUE, END OF PERIOD  $               9.77    $           9.95    $      11.16    $       9.55    $          10.46
                                             -------              ------    ------------    ------------             -------
                                             -------              ------    ------------    ------------             -------
TOTAL RETURN                                   (2.30)%              3.41%          22.11%          (4.18)%             23.35%
                                             -------              ------    ------------    ------------             -------
                                             -------              ------    ------------    ------------             -------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period
 (Thousands)                                 $16,950             $20,194         $74,500         $97,223             $62,245
Ratio of Expenses to Average
 Net Assets (1)                                 0.75%**             0.75%**         0.75%           0.75%               0.75%
Ratio of Net Investment Income
 to Average Net Assets (1)                      9.89%**             8.96%**         8.70%           9.42%              11.09%
Portfolio Turnover Rate                            9%                 24%            104%             74%                 90%
<FN>
- -----------------
(1) Effect of voluntary
expense limitation
    during the period:
    Per share benefit to net
     investment income          $               0.01    $           0.01    $       0.02          $0.001    $           0.01
  Ratios before expense
 limitation:
    Expenses to Average Net
     Assets                                     1.23%**             1.62%**         0.96%           0.76%               0.83%
    Net Investment Income to
     Average Net Assets                         9.41%**             8.09%**         8.49%           9.41%              11.01%
 *Commencement of operations.
**Annualized
</TABLE>
 
- --------------------------------------------------------------------------------
THE MUNICIPAL BOND PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                             PERIOD FROM
                                                       JANUARY 18, 1995*
                                                    TO DECEMBER 31, 1995
- ------------------------------------------------------------------------
<S>                                                 <C>
NET ASSET VALUE, BEGINNING OF PERIOD                $              10.00
                                                                 -------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)                                         0.44
  Net Realized and Unrealized Gain on Investments                   0.42
                                                                 -------
    Total from Investment Operations                                0.86
                                                                 -------
DISTRIBUTIONS
  Net Investment Income                                            (0.45)
  In Excess of Net Investment Income                               (0.00)+
  Net Realized Gain                                                (0.04)
                                                                 -------
    TOTAL DISTRIBUTIONS                                            (0.49)
                                                                 -------
Net Asset Value, End of Period                                    $10.37
                                                                 -------
                                                                 -------
TOTAL RETURN                                                        8.80%
                                                                 -------
                                                                 -------
RATIOS AND SUPPLEMENTAL DATA:
Net Assets, End of Period (Thousands)                            $45,869
Ratio of Expenses to Average Net Assets (1)                         0.45%**
Ratio of Net Investment Income to Average Net
 Assets (1)                                                         4.61%**
Portfolio Turnover Rate                                              180%
<FN>
- -----------------
(1) Effect of voluntary expense limitation during
    the period:
    Per share benefit to net investment income      $               0.03
  Ratios before expense limitation:
    Expenses to Average Net Assets                                  0.73%**
    Net Investment Income to Average Net Assets                     4.33%**
 *Commencement of operations.
**Annualized
 +Amount is less than $0.01 per share.
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
                                      148
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
FINANCIAL HIGHLIGHTS
SELECTED PER SHARE DATA AND RATIOS:
- --------------------------------------------------------------------------------
 
THE MONEY MARKET PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                        TWO MONTHS
                                                             ENDED    YEAR ENDED    YEAR ENDED    YEAR ENDED
                            YEAR ENDED    YEAR ENDED      DECEMBER      DECEMBER      DECEMBER      DECEMBER
                           OCTOBER 31,   OCTOBER 31,           31,           31,           31,           31,
                                  1991          1992          1992          1993          1994          1995
- ------------------------------------------------------------------------------------------------------------
<S>                        <C>           <C>           <C>           <C>           <C>           <C>
NET ASSET VALUE,
 BEGINNING OF PERIOD       $     1.000   $     1.000   $     1.000   $     1.000   $     1.000   $     1.000
                           -----------   -----------   -----------   -----------   -----------   -----------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment Income
   (1)                           0.062         0.039         0.005         0.027         0.040         0.054
                           -----------   -----------   -----------   -----------   -----------   -----------
DISTRIBUTIONS
  Net Investment Income         (0.062)       (0.039)       (0.005)       (0.027)       (0.040)       (0.054)
  In Excess of Net
   Investment Income                --            --            --         0.000+           --            --
                           -----------   -----------   -----------   -----------   -----------   -----------
    Total Distributions         (0.062)       (0.039)       (0.005)       (0.027)       (0.040)       (0.054)
                           -----------   -----------   -----------   -----------   -----------   -----------
NET ASSET VALUE, END OF
 PERIOD                    $     1.000   $     1.000   $     1.000   $     1.000   $     1.000   $     1.000
                           -----------   -----------   -----------   -----------   -----------   -----------
                           -----------   -----------   -----------   -----------   -----------   -----------
TOTAL RETURN                      6.37%         3.77%         0.50%         2.76%         3.84%         5.51%
                           -----------   -----------   -----------   -----------   -----------   -----------
                           -----------   -----------   -----------   -----------   -----------   -----------
RATIOS AND SUPPLEMENTAL
 DATA:
Net Assets, End of Period
 (Thousands)                  $607,087      $612,968      $599,172      $657,163      $690,503      $836,693
Ratio of Expenses to
 Average Net Assets (1)           0.53%         0.52%         0.55%**        0.53%        0.49%         0.51%
Ratio of Net Investment
 Income to Average Net
 Assets (1)                       6.11%         3.74%         3.11%**        2.71%        3.77%         5.37%
<FN>
- ---------------
(1) Effect of voluntary
expense limitation
    during the period:
    Per share benefit to
     net investment
     income                        N/A           N/A   $     0.000+  $     0.000+          N/A           N/A
  Ratios before expense
 limitation:
    Expenses to Average
     Net Assets                    N/A           N/A          0.59%**        0.54%         N/A           N/A
    Net Investment Income
     to Average Net
     Assets                        N/A           N/A          3.07%**        2.70%         N/A           N/A
**Annualized
 +Amount is less than
 $0.001 per share.
</TABLE>
 
- --------------------------------------------------------------------------------
THE MUNICIPAL MONEY MARKET PORTFOLIO
 
- --------------------------------------------------------------------------------
 
<TABLE>
<CAPTION>
                                                        TWO MONTHS
                                                             ENDED    YEAR ENDED    YEAR ENDED    YEAR ENDED
                            YEAR ENDED    YEAR ENDED      DECEMBER      DECEMBER      DECEMBER      DECEMBER
                           OCTOBER 31,   OCTOBER 31,           31,           31,           31,           31,
                                  1991          1992          1992          1993          1994          1995
- ------------------------------------------------------------------------------------------------------------
<S>                        <C>           <C>           <C>           <C>           <C>           <C>
NET ASSET VALUE,
 BEGINNING OF PERIOD       $     1.000   $     1.000   $     1.000   $     1.000   $     1.000   $     1.000
                           -----------   -----------   -----------   -----------   -----------   -----------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment Income
   (1)                           0.043         0.026         0.004         0.019         0.020         0.034
                           -----------   -----------   -----------   -----------   -----------   -----------
DISTRIBUTIONS
  Net Investment Income         (0.043)       (0.026)       (0.004)       (0.019)       (0.020)       (0.034)
  In Excess of Net
   Investment Income                --            --            --        (0.000)+          --            --
                           -----------   -----------   -----------   -----------   -----------   -----------
    Total Distributions         (0.043)       (0.026)       (0.004)       (0.019)       (0.020)       (0.034)
                           -----------   -----------   -----------   -----------   -----------   -----------
NET ASSET VALUE, END OF
 PERIOD                    $     1.000   $     1.000   $     1.000   $     1.000   $     1.000   $     1.000
                           -----------   -----------   -----------   -----------   -----------   -----------
                           -----------   -----------   -----------   -----------   -----------   -----------
TOTAL RETURN                      4.35%         2.74%         0.37%         1.91%         2.44%         3.44%
                           -----------   -----------   -----------   -----------   -----------   -----------
                           -----------   -----------   -----------   -----------   -----------   -----------
RATIOS AND SUPPLEMENTAL
 DATA:
Net Assets, End of Period
 (Thousands)                  $166,953      $206,691      $208,866      $266,524      $359,444      $451,519
Ratio of Expenses to
 Average Net Assets (1)           0.56%         0.55%         0.57%**        0.54%        0.51%         0.52%
Ratio of Net Investment
 Income to Average Net
 Assets (1)                       4.18%         2.66%         2.31%**        1.89%        2.42%         3.38%
<FN>
- ---------------
(1) Effect of voluntary
expense limitation
    during the period:
    Per share benefit to
     net investment
     income                        N/A           N/A   $     0.000+  $     0.000+          N/A           N/A
  Ratios before expense
 limitation:
    Expenses to Average
     Net Assets                    N/A           N/A          0.67%**        0.56%         N/A           N/A
    Net Investment Income
     to Average Net
     Assets                        N/A           N/A          2.21%**        1.87%         N/A           N/A
**Annualized
 +Amount is less than
 $0.001 per share.
</TABLE>
 
    The accompanying notes are an integral part of the financial statements.
 
- --------------------------------------------------------------------------------
                                      149
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
Morgan Stanley Institutional Fund, Inc. (the "Fund") is registered under the
Investment Company Act of 1940 as an open-end management investment company. As
of December 31, 1995, the Fund was comprised of 24 separate active, diversified
and non-diversified portfolios (each referred to as the "Portfolio"). During the
year ended December 31, 1995, the following Portfolios commenced operations:
Latin American Portfolio and Municipal Bond Portfolio on January 18, 1995, the
U.S. Real Estate Portfolio on February 24, 1995, and the Aggressive Equity
Portfolio on March 8, 1995. Please refer to the manager's reports included
elsewhere in this annual report for a description of each Portfolio's investment
objectives.
 
A. The following significant accounting policies are in conformity with
generally accepted accounting principles for investment companies. Such policies
are consistently followed by the Fund in the preparation of the financial
statements. Generally accepted accounting principles may require management to
make estimates and assumptions that affect the reported amounts and disclosures
in the financial statements. Actual results may differ from those estimates. The
U.S. Real Estate Portfolio owns shares of real estate investment trusts
("REITs") which report information on the source of their distributions
annually. A portion of distributions received from REITs during the year is
estimated to be a return of capital and is recorded as a reduction of their
cost.
 
1. SECURITY VALUATION: Equity securities listed on a U.S. exchange and equity
securities traded on NASDAQ are valued at the latest quoted sales price.
Securities listed on a foreign exchange are valued at their closing price.
Unlisted securities and listed securities not traded on the valuation date for
which market quotations are readily available are valued at the mean between the
current bid and asked prices obtained from reputable brokers. Bonds and other
fixed income securities may be valued according to the broadest and most
representative market. In addition, bonds and other fixed income securities may
be valued on the basis of prices provided by a pricing service which are based
primarily on institutional size trading in similar groups of securities. Debt
securities purchased with remaining maturities of 60 days or less are valued at
amortized cost, if it approximates market value. Securities owned by the Money
Market and Municipal Money Market Portfolios are stated at amortized cost, which
approximates market value. All other securities and assets for which market
values are not readily available, including restricted securities, are valued at
fair value as determined in good faith by the Board of Directors, although the
actual calculations may be done by others.
 
2. INCOME TAXES: It is each Portfolio's intention to qualify as a regulated
investment company and distribute all of its taxable and tax-exempt income.
Accordingly, no provision for Federal income taxes is required in the financial
statements.
 
A Portfolio may be subject to taxes imposed by countries in which it invests.
Such taxes are generally based on either income or gains earned or repatriated.
The Portfolio accrues such taxes when the related income is earned. For
investments in securities subject to a capital gains tax, such taxes are accrued
based on the relative amounts of net realized gains and net unrealized
appreciation of such securities. Prior to March 10, 1995, the Brazilian
government assessed a 1% tax on all settlements of foreign currency used to
purchase listed equity securities. The Brazilian government repealed this tax on
March 10, 1995.
 
Paid in capital, undistributed (distributions in excess of) net investment
income/accumulated net investment loss and accumulated gain (loss) have been
adjusted for permanent book-tax differences, if any, for the Portfolios. These
differences are primarily due to differing book-tax treatments for foreign
currency transactions, net operating losses, foreign taxes on net realized
gains, deductibility of interest expense on short sales and gains on certain
securities of corporations designated as "passive foreign investment companies".
 
3. REPURCHASE AGREEMENTS: In connection with transactions in repurchase
agreements, a bank as custodian for the Fund takes possession of the underlying
securities, with a market value at least equal to the amount of the repurchase
transaction, including principal and accrued interest. To the extent that any
repurchase transaction exceeds one business day, the value of the collateral is
marked-to-market on a daily basis to determine the adequacy of the collateral.
In the event of default on the obligation to repurchase, the Fund has the right
to liquidate the collateral and apply the proceeds in satisfaction of the
obligation. In the event of default or bankruptcy by the counter party to the
agreement, realization and/or retention of the collateral or proceeds may be
subject to legal proceedings.
 
4. REVERSE REPURCHASE AGREEMENTS: The Emerging Markets Debt Portfolio may enter
into reverse repurchase agreements with institutions that the Portfolio's
investment adviser has determined are creditworthy. Under a reverse repurchase
agreement, the Portfolio sells securities and agrees to repurchase them at a
mutually agreed upon date and price. Reverse repurchase agreements involve the
risk that the market value of the securities purchased with the proceeds from
the sale of securities received by the Portfolio may decline below the price of
the securities the Portfolio is
 
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                                      150
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        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS (CONT.)
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
obligated to repurchase. Securities subject to repurchase under reverse
repurchase agreements are designated as such in the Statement of Net Assets.
 
At December 31, 1995 the Emerging Markets Debt Portfolio had reverse repurchase
agreements outstanding as follows:
 
<TABLE>
<CAPTION>
                                                  MATURITY IN
                                                    30 TO 90
                                                      DAYS
                                                  ------------
<S>                                               <C>
Maturity Amount.................................   $12,225,000
                                                  ------------
Market Value of Assets Sold Under
 Agreements.....................................   14,250,000
Weighted Average Interest Rate..................       6.503%
                                                  ------------
</TABLE>
 
For the Emerging Markets Debt Portfolio, the average weekly balance of reverse
repurchase agreements outstanding during the year ended December 31, 1995 was
approximately $1,952,000, at a weighted average interest rate of 5.820%.
 
5. FOREIGN CURRENCY TRANSLATION AND FOREIGN INVESTMENTS: The books and records
of the Fund are maintained in United States dollars. Foreign currency amounts
are translated into U.S. dollars at the mean of the bid and asked prices of such
currencies against U.S. dollars last quoted by a major U.S. or foreign bank.
Although the net assets of the Fund are presented at the foreign exchange rates
and market values at the close of the period, the Fund does not isolate that
portion of the results of operations arising as a result of changes in the
foreign exchange rates from the fluctuations arising from changes in the market
prices of the securities held at period end. Similarly, the Fund does not
isolate the effect of changes in foreign exchange rates from the fluctuations
arising from changes in the market prices of securities sold during the period.
Accordingly, realized and unrealized foreign currency gains (losses) are
included in the reported net realized and unrealized gains (losses) on
investment transactions balances. However, pursuant to U.S. Federal income tax
regulations, gains and losses from certain foreign currency transactions are
treated as ordinary income for U.S. Federal income tax purposes.
 
Net realized gains (losses) on foreign currency transactions represent net
foreign exchange gains (losses) from forward foreign currency exchange
contracts, disposition of foreign currencies, currency gains or losses realized
between the trade and settlement dates on securities transactions, and the
difference between the amount of investment income and foreign withholding taxes
recorded on the Fund's books and the U.S. dollar equivalent amounts actually
received or paid. Net unrealized currency gains (losses) from valuing foreign
currency denominated assets and liabilities at period end exchange rates are
reflected as a component of unrealized appreciation (depreciation) on the
Statement of Changes in Net Assets. The change in net unrealized currency gains
(losses) for the period is reflected on the Statement of Operations.
 
Foreign security and currency transactions may involve certain considerations
and risks not typically associated with those of U.S. dollar denominated
transactions as a result of, among other factors, the possibility of lower
levels of governmental supervision and regulation of foreign securities markets
and the possibility of political or economic instability.
 
6. FORWARD FOREIGN CURRENCY EXCHANGE CONTRACTS: Each Portfolio, except the
Equity Growth, U.S. Real Estate, Municipal Bond, Money Market and Municipal
Money Market Portfolios, may enter into forward currency exchange contracts to
attempt to protect securities and related receivables and payables against
changes in future foreign currency exchange rates. A forward currency exchange
contract is an agreement between two parties to buy or sell currency at a set
price on a future date. The market value of the contract will fluctuate with
changes in currency exchange rates. The contract is marked-to-market daily using
the forward rate and the change in market value is recorded by the Fund as
unrealized gain or loss. The Fund records realized gains or losses when the
contract is closed equal to the difference between the value of the contract at
the time it was opened and the value at the time it was closed. Risk may arise
upon entering into these contracts from the potential inability of
counterparties to meet the terms of their contracts and is generally limited to
the amount of the unrealized gain on the contracts (if any) at the date of
default. Risks may also arise from unanticipated movements in the value of a
foreign currency relative to the U.S. dollar.
 
7. FORWARD COMMITMENTS AND WHEN-ISSUED/DELAYED DELIVERY SECURITIES: Each
Portfolio may make forward commitments to purchase or sell securities. Payment
and delivery for securities which have been purchased or sold on a forward
commitment basis can take place a month or more (not to exceed 120 days) after
the date of the transaction. Additionally, certain Portfolios may purchase
securities on a when-issued or delayed-delivery basis. Securities purchased on a
when-issued or delayed delivery basis are purchased for delivery beyond the
normal settlement date at a stated price and yield, and no income accrues to the
Portfolio on such securities prior to delivery. When the Portfolio enters into a
purchase transaction on a when-issued or delayed delivery basis, it establishes
a segregated account in which it maintains liquid assets in an amount at least
equal in value to the Portfolio's commitments to purchase such securities.
Purchasing
 
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                                      151
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        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS (CONT.)
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
securities on a forward commitment or when-issued or delayed-delivery basis may
involve a risk that the market price at the time of delivery may be lower than
the agreed-upon purchase price, in which case there could be an unrealized loss
at the time of delivery.
 
8. LOAN AGREEMENTS: The Emerging Markets, Emerging Markets Debt and High Yield
Portfolios may invest in fixed and floating rate loans ("Loans") arranged
through private negotiations between an issuer of sovereign debt obligations and
one or more financial institutions ("Lenders") deemed to be creditworthy by the
investment adviser. The Portfolio's investments in Loans may be in the form of
participations in Loans ("Participations") or assignments of all or a portion of
Loans ("Assignments") from third parties. The Portfolio's investment in
Participations typically results in the Portfolio having a contractual
relationship with only the Lender and not with the borrower. The Portfolio has
the right to receive payments of principal, interest and any fees to which it is
entitled only from the Lender selling the Participation and only upon receipt by
the Lender of the payments from the borrower. The Portfolio generally has no
right to enforce compliance by the borrower with the terms of the loan
agreement. As a result, the Portfolio may be subject to the credit risk of both
the borrower and the Lender that is selling the Participation. When the
Portfolio purchases Assignments from Lenders, it acquires direct rights against
the borrower on the Loan. Because Assignments are arranged through private
negotiations between potential assignees and potential assignors, the rights and
obligations acquired by the Portfolio as the purchaser of an Assignment may
differ from, and be more limited than, those held by the assigning Lender.
 
9. SHORT SALES: The Aggressive Equity and Emerging Markets Debt Portfolios may
sell securities short. A short sale is a transaction in which the Portfolio
sells securities it does not own, but has borrowed, in anticipation of a decline
in the market price of the securities. The Portfolio is obligated to replace the
borrowed securities at the market price at the time of replacement. The
Portfolio may have to pay a premium to borrow the securities as well as pay any
dividends or interest payable on the securities until they are replaced. The
Portfolio's obligation to replace the securities borrowed in connection with a
short sale will generally be secured by collateral deposited with the broker
that consists of cash, U.S. government securities or other liquid, high grade
debt obligations. In addition, the Portfolio will place in a segregated account
with its Custodian an amount of cash, U.S. government securities or other liquid
high grade debt obligations equal to the difference, if any, between (1) the
market value of the securities sold at the time they were sold short and (2) any
cash, U.S. government securities or other liquid high grade debt obligations
deposited as collateral with the broker in connection with the short sale (not
including the proceeds of the short sale). Short sales by the Portfolio involve
certain risks and special considerations. Possible losses from short sales
differ from losses that could be incurred from a purchase of a security, because
losses from short sales may be unlimited, whereas losses from purchases cannot
exceed the total amount invested.
 
10. PURCHASED AND WRITTEN OPTIONS: Certain Portfolios may write covered call and
put options on their securities. Premiums are received and are recorded as
liabilities, and subsequently adjusted to the current value of the options
written. Premiums received from writing options which expire are treated as
realized gains. Premiums received from writing options which are exercised or
are canceled in closing purchase transactions are offset against the proceeds or
amount paid on the transaction to determine the realized gain or loss. By
writing a covered call option, a Portfolio foregoes in exchange for the premium
the opportunity for capital appreciation above the exercise price should the
market price of the underlying security increase. By writing a covered put
option, a Portfolio, in exchange for the premium, accepts the risk of a decline
in the market value of the underlying security below the exercise price.
 
Certain Portfolios may purchase call and put options on their portfolio
securities. Each Portfolio may purchase call options to close out covered
written call positions or to protect against an increase in the price of the
security it anticipates purchasing. Each Portfolio may purchase put options on
their securities to protect against a decline in the value of the security or to
close out covered written put positions. Possible losses from purchased options
cannot exceed the total amount invested.
 
11. OTHER: Security transactions are accounted for on the date the securities
are purchased or sold. Costs used in determining realized gains and losses on
the sale of investment securities are those of specific securities sold.
Dividend income is recorded on the ex-dividend date. Interest income is
recognized on the accrual basis except where collection is in doubt. Discounts
and premiums on securities purchased (other than mortgage-backed securities) are
amortized according to the effective yield method over their respective lives.
Most expenses of the Fund can be directly attributed to a particular Portfolio.
Expenses which cannot be directly attributed are apportioned among
 
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                                      152
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        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS (CONT.)
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
the Portfolios based upon relative average net assets. Dividends to the
shareholders of the Money Market and the Municipal Money Market Portfolios are
accrued daily and are distributed on or about the 15th of each month.
Distributions from the remaining Portfolios are recorded on the ex-date.
 
Income distributions and capital gain distributions are determined in accordance
with U.S. Federal income tax regulations which may differ from generally
accepted accounting principles. These differences are primarily due to the
timing of the recognition of gains or losses on securities and forward currency
exchange contracts, the timing of the deductibility of certain foreign taxes,
dividends received from real estate investment trusts and permanent differences
as presented in Note A-2.
 
Current period permanent book-tax differences, if any, are not included in
ending undistributed (distributions in excess of) net investment
income/accumulated net investment loss for the purpose of calculating net
investment income (loss) per share in the Financial Highlights.
 
Prior governmental approval for foreign investments may be required under
certain circumstances in some emerging countries, and the extent of foreign
investment in domestic companies may be subject to limitation in other emerging
countries. Foreign ownership limitations also may be imposed by the charters of
individual companies in emerging countries to prevent, among other concerns,
violation of foreign investment limitations. As a result, an additional class of
shares (identified as "Foreign" in the Statement of Net Assets) may be created
and offered for investment. The "local" and "foreign" shares' market values may
differ.
 
A transaction fee of one percent is charged on subscriptions and redemptions of
capital shares of the International Small Cap Portfolio. Such fees are paid to
or retained by the Portfolio and included in paid in capital. During the year
ended December 31, 1995, such transaction fees totaled approximately $827,000.
 
B. Morgan Stanley Asset Management Inc. ("MSAM") (the "Adviser") provides the
Fund with investment advisory services at a fee calculated at the annual rates
of average daily net assets indicated below. MSAM has agreed to reduce fees
payable to it and to reimburse the Portfolios, if necessary, if the annual
operating expenses, as defined, expressed as a percentage of average daily net
assets, exceed the maximum ratios indicated as follows:
 
<TABLE>
<CAPTION>
                                          ADVISORY       MAXIMUM
PORTFOLIO                                   FEE       EXPENSE RATIO
                                        ------------  -------------
<S>                                     <C>           <C>
Active Country Allocation.............         .65%          .80%
Asian Equity..........................         .80          1.00
Emerging Markets......................        1.25          1.75
European Equity.......................         .80          1.00
Global Equity.........................         .80          1.00
Gold..................................        1.00          1.25
International Equity..................         .80          1.00
International Small Cap...............         .95          1.15
Japanese Equity.......................         .80          1.00
Latin American........................        1.10          1.70
Aggressive Equity.....................         .80          1.00
Emerging Growth.......................        1.00          1.25
Equity Growth.........................         .60           .80
Small Cap Value Equity................         .85          1.00
U.S. Real Estate......................         .80          1.00
Value Equity..........................         .50           .70
Balanced..............................         .50           .70
Emerging Markets Debt.................        1.00          1.75
Fixed Income..........................         .35           .45
Global Fixed Income...................         .40           .50
High Yield............................         .50           .75
Municipal Bond........................         .35           .45
Money Market..........................         .30           .55
Municipal Money Market................         .30           .57
</TABLE>
 
Sun Valley Gold Company is the sub-adviser ("Sub-Adviser") of the Gold
Portfolio. The Sub-Adviser is entitled to receive an annual sub-advisory fee in
an amount equal to .40% of the average daily net assets of the Portfolio. The
Sub-Adviser has agreed to a proportionate reduction in its fees if the Adviser
is required to waive its fees or to reimburse the Portfolio.
 
C. MSAM also provides the Fund with administrative services pursuant to an
administrative agreement, for a monthly fee which on an annual basis equals
0.15% of the average daily net assets of each Portfolio plus reimbursement of
out-of-pocket expenses. Under an agreement between MSAM and The Chase Manhattan
Bank, N.A. ("Chase"), effective September 1, 1995, Chase, through its affiliate
Chase Global Funds Services Company, formerly Mutual Funds Service Company
("MFSC"), provides certain administrative services to the Fund. For such
services, MSAM pays Chase a portion of the fee MSAM receives from the Fund.
Prior to September 1, 1995, MFSC was an affiliate of United States Trust Company
of New York ("UST") and provided certain administrative services to the Fund
under the same terms as stated above.
 
D. Morgan Stanley Trust Company ("MSTC") acts as custodian for the Fund's assets
held outside the United States in accordance with a custodian agreement.
Custodian fees are computed and payable monthly based on securities held,
investment purchases and sales activity, an account maintenance fee, plus
reimbursement for certain out-of-pocket expenses. MSTC and the Adviser are
wholly-owned subsidiaries of Morgan Stanley Group, Inc.
 
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                                      153
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[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS (CONT.)
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
Effective September 1, 1995, Chase replaced UST as custodian for the Fund's
assets held in the United States.
 
For the year ended December 31, 1995, the following Portfolios incurred custody
fees and had amounts due to MSTC at December 31, 1995 totaling:
 
<TABLE>
<CAPTION>
                                MSTC CUSTODY
                                    FEES        FEES PAYABLE TO
                                  INCURRED           MSTC
                                    (000)            (000)
                                -------------  -----------------
<S>                             <C>            <C>
Active Country Allocation.....    $     397        $      70
Asian Equity..................          466              111
Emerging Markets..............        2,062              399
European Equity...............           44               11
Global Equity.................           40               11
Gold..........................            9                1
International Equity..........          532              141
International Small Cap.......          117               29
Japanese Equity...............           33               11
Latin American................          104               27
Emerging Markets Debt.........          197               49
Global Fixed Income...........           36                9
</TABLE>
 
In addition, for the year ended December 31, 1995, the following Portfolios have
earned interest income and incurred interest expense on balances with MSTC as
follows:
 
<TABLE>
<CAPTION>
                              INTEREST INCOME    INTEREST EXPENSE
                                   (000)               (000)
                             -----------------  -------------------
<S>                          <C>                <C>
Active Country
 Allocation................      $      29           $      53
Asian Equity...............             58                  17
Emerging Markets...........             42                  69
European Equity............            156                   3
Global Equity..............              9                   1
International Equity.......          1,644                  39
International Small Cap....             84                   6
Japanese Equity............              2                  13
Latin American.............              1                   3
Emerging Markets Debt......             38                  94
Global Fixed Income........             87                   3
</TABLE>
 
At December 31, 1995, the Emerging Markets Portfolio owned shares of an
affiliated fund for which the Portfolio earned dividend income of $219,000.
 
E. During the year ended December 31, 1995, purchases and sales of investment
securities other than long-term U.S. Government securities and short-term
investments were:
 
<TABLE>
<CAPTION>
                                                  (000)
                                          ----------------------
PORTFOLIO                                  PURCHASES     SALES
- ----------------------------------------  -----------  ---------
<S>                                       <C>          <C>
Active Country Allocation...............   $ 115,608   $ 155,753
Asian Equity............................     116,591     114,296
Emerging Markets........................     536,860     475,065
European Equity.........................      42,814       6,125
Global Equity...........................      22,401      38,489
Gold....................................       8,137      32,525
International Equity....................     472,776     364,466
International Small Cap.................      79,415      43,618
Japanese Equity.........................      88,100      29,619
Latin American..........................      32,425      16,689
Aggressive Equity.......................      75,727      52,711
Emerging Growth.........................      31,159      66,673
Equity Growth...........................     246,443     231,522
Small Cap Value Equity..................      19,861      16,332
U.S. Real Estate........................     122,466      62,011
Value Equity............................      92,679      46,530
Balanced................................       4,611       5,122
Emerging Markets Debt...................     616,750     637,624
Fixed Income............................     173,429     182,202
Global Fixed Income.....................     159,473     175,658
High Yield..............................      58,042      95,389
Municipal Bond..........................     118,467      74,955
</TABLE>
 
Purchases and sales during the year ended December 31, 1995 of long-term U.S.
Government securities occurred only in the Balanced, Fixed Income and Global
Fixed Income Portfolios and amounted to:
 
<TABLE>
<CAPTION>
                                                  (000)
                                          ----------------------
PORTFOLIO                                  PURCHASES     SALES
- ----------------------------------------  -----------  ---------
<S>                                       <C>          <C>
Balanced................................   $   1,113   $      --
Fixed Income............................     112,464     151,037
Global Fixed Income.....................      24,602      32,115
</TABLE>
 
During the year ended December 31, 1995, the following Portfolios incurred
brokerage commissions related to Morgan Stanley & Co., Incorporated, an
affiliated broker/dealer, of approximately:
 
<TABLE>
<CAPTION>
                                                      (000)
                                                 ---------------
                                                    BROKERAGE
PORTFOLIO                                          COMMISSION
- -----------------------------------------------  ---------------
<S>                                              <C>
Asian Equity...................................     $      99
Emerging Markets...............................            69
European Equity................................             4
Global Equity..................................             3
Gold...........................................             1
International Equity...........................            69
International Small Cap........................             1
Japanese Equity................................           121
Latin American.................................             4
Equity Growth..................................             1
U.S. Real Estate...............................             6
</TABLE>
 
- --------------------------------------------------------------------------------
                                      154
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS (CONT.)
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
F. At December 31, 1995, cost and unrealized appreciation (depreciation) for
U.S. Federal income tax purposes of the investments of each Portfolio were:
 
<TABLE>
<CAPTION>
                                               (000)
                            --------------------------------------------
                                                                 NET
                                                               APPREC.
PORTFOLIO                     COST      APPREC.    DEPREC.    (DEPREC.)
- --------------------------  ---------  ---------  ---------  -----------
<S>                         <C>        <C>        <C>        <C>
Active Country
 Allocation...............  $ 150,104  $  14,780  $  (4,620)  $  10,160
Asian Equity..............    270,401     58,854    (16,312)     42,542
Emerging Markets..........    915,174     97,063   (150,829)    (53,766)
European Equity...........     65,638      5,746     (2,983)      2,763
Global Equity.............     68,989     11,625     (2,744)      8,881
Gold......................      7,729        246       (651)       (405)
International Equity......  1,265,148    305,267    (31,924)    273,343
International Small Cap...    202,263     16,894    (24,355)     (7,461)
Japanese Equity...........    114,012      4,851     (3,036)      1,815
Latin American............     15,535      1,098     (1,194)        (96)
Aggressive Equity.........     28,800      2,001       (314)      1,687
Emerging Growth...........     66,320     53,480       (542)     52,938
Equity Growth.............    142,804     17,849     (1,941)     15,908
Small Cap Value Equity....     46,841      6,840     (1,886)      4,954
U.S. Real Estate..........     65,257      5,625     (1,810)      3,815
Value Equity..............    132,222     20,118     (5,352)     14,766
Balanced..................     20,531      2,426       (526)      1,900
Emerging Markets Debt.....    173,477     12,534     (5,407)      7,127
Fixed Income..............    155,055      8,025         (5)      8,020
Global Fixed Income.......    109,218      3,611       (262)      3,349
High Yield................     62,766      2,929     (3,708)       (779)
Municipal Bond............     43,334      1,635         --       1,635
Money Market..............    836,431         --         --          --
Municipal Money Market....    450,017         --         --          --
</TABLE>
 
At December 31, 1995, the following Portfolios had available capital loss
carryforwards to offset future net capital gains, to the extent provided by
regulations, through the indicated expiration dates:
 
<TABLE>
<CAPTION>
                                         EXPIRATION DATE
                                          DECEMBER 31,
                                              (000)
                                 -------------------------------
PORTFOLIO                          2001       2002       2003       TOTAL
- -------------------------------     ---     ---------  ---------  ---------
<S>                              <C>        <C>        <C>        <C>
Emerging Markets...............  $      --  $      --  $  33,313  $  33,313
Japanese Equity................         --         --      2,666      2,666
Latin American.................         --         --        224        224
Fixed Income...................         --      8,291         --      8,291
Global Fixed Income............         --      5,293      1,780      7,073
High Yield.....................         --        497      4,145      4,642
Money Market...................         --         13         --         13
Municipal Money Market.........          1          7          1          9
</TABLE>
 
During the year ended December 31, 1995, the International Small Cap, Emerging
Growth, Fixed Income and Money Market Portfolios utilized capital loss
carryforwards for U.S. Federal income tax purposes of approximately $1,764,000,
$10,861,000, $5,579,000 and $79,000, respectively.
To the extent that capital loss carryovers are used to offset any future net
capital gains realized during the carryover period as provided by U.S. Federal
income tax regulations, no capital gains tax liability will be incurred by a
Portfolio for gains realized and not distributed. It is unlikely that the gains
so offset would be distributed to shareholders.
 
Net capital and net currency losses incurred after October 31 and within the
taxable year are deemed to arise on the first business day of the Portfolio's
next taxable year. For the period from November 1, 1995 to December 31, 1995
certain Portfolios incurred and elected to defer until January 1, 1996 for U.S.
Federal income tax purposes net capital and net currency losses of
approximately:
 
<TABLE>
<CAPTION>
                                               CAPITAL     CURRENCY
                                               LOSSES       LOSSES
PORTFOLIO                                       (000)        (000)
- -------------------------------------------  -----------  -----------
<S>                                          <C>          <C>
Emerging Markets...........................   $      --    $      64
Global Equity..............................          --            2
Latin American.............................           2            6
Emerging Markets Debt......................         245        1,501
High Yield.................................          73           --
Municipal Money Market.....................           1           --
</TABLE>
 
G. During the year ended December 31, 1995, the following Portfolios wrote
covered call and put options as follows:
 
COVERED CALL OPTIONS
 
<TABLE>
<CAPTION>
                                         NUMBER OF       PREMIUM
AGGRESSIVE EQUITY PORTFOLIO              CONTRACTS        (000)
- -------------------------------------  -------------  -------------
<S>                                    <C>            <C>
Options outstanding at December 31,
 1994................................           --      $      --
Options written during the period....          386             39
Options cancelled in closing
 transactions during the period......         (386)           (39)
                                             -----            ---
Options outstanding at December 31,
 1995................................           --      $      --
                                             -----            ---
                                             -----            ---
</TABLE>
 
<TABLE>
<CAPTION>
                                      FACE AMOUNT     PREMIUM
EMERGING MARKETS DEBT PORTFOLIO          (000)         (000)
- -----------------------------------  -------------  -----------
<S>                                  <C>            <C>
Options outstanding at December 31,
 1994..............................    $  15,000     $     105
Options written during the
 period............................       69,900         1,281
Options cancelled in closing
 transactions during the period....      (11,000)         (240)
Options expired during the
 period............................      (43,900)         (508)
Options exercised during the
 period............................      (30,000)         (638)
                                     -------------  -----------
Options outstanding at December 31,
 1995..............................    $      --     $      --
                                     -------------  -----------
                                     -------------  -----------
</TABLE>
 
COVERED PUT OPTIONS
 
<TABLE>
<CAPTION>
                                         NUMBER OF       PREMIUM
AGGRESSIVE EQUITY PORTFOLIO              CONTRACTS        (000)
- -------------------------------------  -------------  -------------
<S>                                    <C>            <C>
Options outstanding at December 31,
 1994................................           --      $      --
Options written during the period....           60             10
Options cancelled in closing
 transactions during the period......          (60)           (10)
                                               ---            ---
Options outstanding at December 31,
 1995................................           --      $      --
                                               ---            ---
                                               ---            ---
</TABLE>
 
H. OTHER. At December 31, 1995, the net assets of certain Portfolios were
substantially comprised of foreign denominated securities and currency. Changes
in currency exchange rates will affect the U.S. dollar value of and investment
income from such securities.
 
- --------------------------------------------------------------------------------
                                      155
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
NOTES TO FINANCIAL STATEMENTS (CONT.)
DECEMBER 31, 1995
- --------------------------------------------------------------------------------
 
During the year ended December 31, 1995, the Gold Portfolio realized losses from
in-kind redemptions of approximately $252,000.
 
Portfolio securities and foreign currency holdings were translated at the
following exchange rates as of December 31, 1995:
 
<TABLE>
<S>                                     <C>          <C>        <C>
Argentine Peso........................      1.00015      =      $    1.00
Australian Dollar.....................      1.34544      =      $    1.00
Belgian Franc.........................     29.43000      =      $    1.00
Brazilian Real........................      0.97190      =      $    1.00
British Pound.........................      0.64412      =      $    1.00
Canadian Dollar.......................      1.36505      =      $    1.00
Colombian Peso........................    990.75000      =      $    1.00
Danish Krone..........................      5.55680      =      $    1.00
Deutsche Mark.........................      1.43390      =      $    1.00
Finnish Markka........................      4.34955      =      $    1.00
French Franc..........................      4.89700      =      $    1.00
Greek Drachma.........................    236.99000      =      $    1.00
Hong Kong Dollar......................      7.73250      =      $    1.00
Hungarian Forint......................    136.63000      =      $    1.00
Indonesian Rupiah.....................  2,286.50000      =      $    1.00
Irish Pound...........................      0.62441      =      $    1.00
Italian Lira..........................  1,588.25000      =      $    1.00
Japanese Yen..........................    103.25000      =      $    1.00
Korean Won............................    775.75000      =      $    1.00
Malaysian Ringgit.....................      2.53970      =      $    1.00
Mexican Peso..........................      7.69500      =      $    1.00
Moroccan Dirham.......................      8.46890      =      $    1.00
Netherlands Guilder...................      1.60470      =      $    1.00
New Zealand Dollar....................      1.52964      =      $    1.00
Norwegian Krone.......................      6.32905      =      $    1.00
Pakistani Rupee.......................     34.21580      =      $    1.00
Peruvian New Sol......................      2.31000      =      $    1.00
Philippine Peso.......................     26.23000      =      $    1.00
Polish Zloty..........................      2.46550      =      $    1.00
Portuguese Escudo.....................    149.67500      =      $    1.00
Singapore Dollar......................      1.41450      =      $    1.00
Spanish Peseta........................    121.30000      =      $    1.00
Sri Lanka Rupee.......................     53.65000      =      $    1.00
Swedish Krona.........................      6.63965      =      $    1.00
Swiss Franc...........................      1.15350      =      $    1.00
Taiwan Dollar.........................     27.28700      =      $    1.00
Thai Baht.............................     25.19000      =      $    1.00
Turkish Lira..........................  60,900.00000     =      $    1.00
</TABLE>
 
From time to time, certain Portfolios of the Fund have shareholders that hold a
significant portion of a Portfolio's outstanding shares. Investment activities
of these shareholders could have a material impact on those Portfolios.
 
I. SUBSEQUENT EVENT. On January 2, 1996, each Portfolio (with the exception of
the International Small Cap, Money Market and Municipal Money Market Portfolios)
began offering two classes of shares -- Class A and Class B. All the shares of
these Portfolios outstanding prior to January 2, 1996, were redesignated Class A
shares on January 2, 1996.
 
- --------------------------------------------------------------------------------
                                      156
<PAGE>
[LOGO]  Morgan Stanley
        Institutional Fund, Inc.
- --------------------------------------------------------------------------------
 
REPORT OF INDEPENDENT ACCOUNTANTS
- --------------------------------------------------------------------------------
 
To the Shareholders and Board of Directors of
Morgan Stanley Institutional Fund, Inc.
 
In our opinion, the accompanying statements of net assets and the related
statements of operations and of changes in net assets and the financial
highlights present fairly, in all material respects, the financial position of
the Active Country Allocation Portfolio, Asian Equity Portfolio, Emerging
Markets Portfolio, European Equity Portfolio, Global Equity Portfolio, Gold
Portfolio, International Equity Portfolio, International Small Cap Portfolio,
Japanese Equity Portfolio, Latin American Portfolio, Aggressive Equity
Portfolio, Emerging Growth Portfolio, Equity Growth Portfolio, Small Cap Value
Equity Portfolio, U.S. Real Estate Portfolio, Value Equity Portfolio, Balanced
Portfolio, Emerging Markets Debt Portfolio, Fixed Income Portfolio, Global Fixed
Income Portfolio, High Yield Portfolio, Municipal Bond Portfolio, Money Market
Portfolio and Municipal Money Market Portfolio (constituting the Morgan Stanley
Institutional Fund, Inc., hereafter referred to as the "Fund") at December 31,
1995, the results of each of their operations, the changes in each of their net
assets and the financial highlights for the periods indicated, in conformity
with generally accepted accounting principles. These financial statements and
financial highlights (hereafter referred to as "financial statements") are the
responsibility of the Fund's management; our responsibility is to express an
opinion on these financial statements based on our audits. We conducted our
audits of these financial statements in accordance with generally accepted
auditing standards which require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements are free of material
misstatement. An audit includes examining, on a test basis, evidence supporting
the amounts and disclosures in the financial statements, assessing the
accounting principles used and significant estimates made by management, and
evaluating the overall financial statement presentation. We believe that our
audits, which included confirmation of securities at December 31, 1995 by
correspondence with the custodians and counterparties and the application of
alternative auditing procedures where confirmations from counterparties were not
received, provide a reasonable basis for the opinion expressed above.
 
PRICE WATERHOUSE LLP
1177 Avenue of the Americas
New York, New York 10036
 
February 9, 1996
 
- --------------------------------------------------------------------------------
 
- --------------------------------------------------------------------------------
 
                                      157
<PAGE>

                                        PART C

                       Morgan Stanley Institutional Fund, Inc.
                                  Other Information



ITEM 24. FINANCIAL STATEMENTS AND EXHIBITS

    (A)  FINANCIAL STATEMENTS

   
              The Registrant's audited financial statements for the Money
              Market, Municipal Money Market, Aggressive Equity, Emerging
              Growth, Equity Growth, Value Equity, Small Cap Value Equity, U.S.
              Real Estate, Balanced, Active Country Allocation, Global Equity,
              International Equity, International Small Cap, European Equity,
              Asian Equity, Emerging Markets, Gold, Japanese Equity, Latin
              American, Emerging Markets Debt, Fixed Income, Global Fixed
              Income, High Yield and Municipal Bond Portfolios, respectively,
              for the fiscal year ended December 31, 1995, and Price Waterhouse
              LLP's report thereon, are included in Part B (the Statement of
              Additional Information) from the Registrant's December 31, 1995
              Annual Report to Shareholders. Included in such financial
              statements are the following:

              1.   Report of Independent Accountants
              2.   Statement of Net Assets at December 31, 1995
              3.   Statement of Operations for the period ended December 31,
                   1995
              4.   Statement of Changes in Net Assets for the respective
                   periods presented in the two year period ended December 31,
                   1995
              5.   Financial Highlights for the respective periods presented in
                   the five year period ended December 31, 1995
              6.   Notes to Financial Statements
    

    (B)  EXHIBITS
   
    1    Articles of Amendment and Restatement are incorporated by reference to
         Post-Effective Amendment No. 26 to the Registrant's Registration
         Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as filed
         with the SEC via EDGAR on October 13, 1995.

    2    Amended and Restated By-laws are incorporated by reference to Post-
         Effective Amendment No. 25 to the Registrant's Registration Statement
         on Form N-1A (File Nos. 33-23166 and 811-5624), as filed with the SEC
         via EDGAR on August 1, 1995.

    3    Not Applicable.

    4    Registrant's Form of Specimen Security was previously filed and is
         incorporated herein by reference.

    5    (a)  Investment Advisory Agreement between Registrant and Morgan
              Stanley Asset Management Inc. is incorporated by reference to
              Post-Effective Amendment No. 25 to the Registrant's Registration
              Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
              filed with the SEC via EDGAR on August 1, 1995.

         (b)  Supplement to Investment Advisory Agreement between Registrant
              and Morgan Stanley Asset Management Inc.  (adding Registrant's
              Equity, Balanced and Fixed Income Portfolios) is incorporated by
              reference to Post-Effective Amendment No. 25 to the Registrant's
              Registration Statement on Form N-1A (File Nos. 33-23166 and 
              811-5624), as filed with the SEC via EDGAR on August 1, 1995.

         (c)  Supplement to Investment Advisory Agreement between Registrant
              and Morgan Stanley Asset Management Inc. (adding the Global
              Equity, Global Fixed Income, European Equity and Equity
    
<PAGE>
   
              Growth Portfolios) is incorporated by reference to Post-Effective
              Amendment No. 25 to the Registrant's Registration Statement on
              Form N-1A (File Nos. 33-23166 and 811-5624), as filed with the
              SEC via EDGAR on August 1, 1995.

         (d)  Supplement to Investment Advisory Agreement between Registrant
              and Morgan Stanley Asset Management Inc. (adding the Asian Equity
              Portfolio) is incorporated by reference to Post-Effective
              Amendment No. 25 to the Registrant's Registration Statement on
              Form N-1A (File Nos. 33-23166 and 811-5624), as filed with the
              SEC via EDGAR on August 1, 1995.

         (e)  Supplement to Investment Advisory Agreement between Registrant
              and Morgan Stanley Asset Management Inc. (adding the Active
              Country Allocation Portfolio) is incorporated by reference to
              Post-Effective Amendment No. 25 to the Registrant's Registration
              Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
              filed with the SEC via EDGAR on August 1, 1995.

         (f)  Supplement to Investment Advisory Agreement between Registrant
              and Morgan Stanley Asset Management Inc. (adding the Emerging
              Markets, High Yield and International Small Cap Portfolios) is
              incorporated by reference to Post-Effective Amendment No. 25 to
              the Registrant's Registration Statement on Form N-1A (File Nos.
              33-23166 and 811-5624), as filed with the SEC via EDGAR on August
              1, 1995.

         (g)  Supplement to Investment Advisory Agreement between Registrant
              and Morgan Stanley Asset Management Inc. (adding the Small Cap
              Value Equity Portfolio) is incorporated by reference to Post-
              Effective Amendment No. 25 to the Registrant's Registration
              Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
              filed with the SEC via EDGAR on August 1, 1995.

         (h)  Supplement to Investment Advisory Agreement between Registrant
              and Morgan Stanley Asset Management Inc. (adding the Emerging
              Markets Debt, Mortgage-Backed Securities, Municipal Bond and
              Japanese Equity Portfolios) is incorporated by reference to 
              Post-Effective Amendment No. 25 to the Registrant's Registration
              Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
              filed with the SEC via EDGAR on August 1, 1995.

         (i)  Sub-Advisory Agreement among Registrant, Morgan Stanley Asset
              Management Inc. and Sun Valley Gold Company (with respect to the
              Gold Portfolio) is incorporated by reference to Post-Effective
              Amendment No. 25 to the Registrant's Registration Statement on
              Form N-1A (File Nos. 33-23166 and 811-5624), as filed with the
              SEC via EDGAR on August 1, 1995.

         (j)  Supplement to Investment Advisory Agreement between Registrant
              and Morgan Stanley Asset Management Inc. (adding the China Growth
              Portfolio) is incorporated by reference to Post-Effective
              Amendment No. 25 to the Registrant's Registration Statement on
              Form N-1A (File Nos. 33-23166 and 811-5624), as filed with the
              SEC via EDGAR on August 1, 1995.

         (k)  Supplement to Investment Advisory Agreement between Registrant
              and Morgan Stanley Asset Management Inc. (adding the Latin
              American Portfolio) is incorporated by reference to Post-
              Effective Amendment No. 25 to the Registrant's Registration
              Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
              filed with the SEC via EDGAR on August 1, 1995.

         (l)  Supplement to Investment Advisory Agreement between Registrant
              and Morgan Stanley Asset Management Inc. (adding the Contrarian
              Portfolio) is incorporated by reference to Post-Effective
              Amendment No. 25 to the Registrant's Registration Statement on
              Form N-1A (File Nos. 33-23166 and 811-5624), as filed with the
              SEC via EDGAR on August 1, 1995.

         (m)  Supplement to Investment Advisory Agreement between Registrant
              and Morgan Stanley Asset Management Inc. (adding the Aggressive
              Equity and U.S. Real Estate Portfolios) is incorporated by
              reference to Post-Effective Amendment No. 25 to the Registrant's
              Registration Statement on Form N-1A (File Nos. 33-23166 and 
              811-5624), as filed with the SEC via EDGAR on August 1, 1995.

         (n)  Supplement to Investment Advisory Agreement between Registrant
              and Morgan Stanley Asset Management, Inc. (adding the MicroCap
              Portfolio) is incorporated by reference to Post-Effective

                                         C-2
    
<PAGE>
   
              Amendment No. 25 to the Registrant's Registration Statement on
              Form N-1A (File Nos. 33-23166 and 811-5624), as filed with the
              SEC via EDGAR on August 1, 1995.

         (o)  Supplement to Investment Advisory Agreement between Registrant
              and Morgan Stanley Asset Management, Inc. (adding the
              International Magnum Portfolio) is incorporated by reference to
              Post-Effective Amendment No. 28 to the Registrant's Registration
              Statement on Form N1-A (File Nos. 33-23166 and 811-5624), as
              filed with the SEC via EDGAR on November 3, 1995.

    6    (a)  Distribution Agreement between Registrant and Morgan Stanley &
              Co. Incorporated is incorporated by reference to Post-Effective
              Amendment No. 25 to the Registrant's Registration Statement on
              Form N-1A (File Nos. 33-23166 and 811-5624), as filed with the
              SEC via EDGAR on August 1, 1995.

         (b)  Supplement to Distribution Agreement between Registrant and
              Morgan Stanley & Co. Incorporated, filed herewith.

    8    (a)  Mutual Fund Custody Agreement (Domestic Custody Agreement)
              between Registrant and United States Trust Company of New York
              dated March 10, 1994 is incorporated by reference to Post-
              Effective Amendment No. 25 to the Registrant's Registration
              Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
              filed with the SEC via EDGAR on August 1, 1995.

         (b)  Registrant's Custody Agreement (International), dated July 31,
              1989, as amended on [____________, 1995] is incorporated by
              reference to Post-Effective Amendment No. 25 to the Registrant's
              Registration Statement on Form N-1A (File Nos. 33-23166 and 
              811-5624), as filed with the SEC via EDGAR on August 1, 1995.

    9    (a)  Administration Agreement between Registrant and Morgan Stanley
              Asset Management Inc. (the "MSAM Administration Agreement") is
              incorporated by reference to Post-Effective Amendment No. 25 to
              the Registrant's Registration Statement on Form N-1A (File Nos.
              33-23166 and 811-5624), as filed with the SEC via EDGAR on August
              1, 1995.

         (b)  U.S. Trust Administration Agreement is incorporated by reference
              to Post-Effective Amendment No. 25 to the Registrant's
              Registration Statement on Form N-1A (File Nos. 33-23166 and 
              811-5624), as filed with the SEC via EDGAR on August 1, 1995.

    10   Opinion of Counsel is incorporated by reference to Post-Effective
         Amendment No. 25 to the Registrant's Registration Statement on Form 
         N-1A (File Nos. 33-23166 and 811-5624), as filed with the SEC via 
         EDGAR on August 1, 1995.

    11   Consent of Independent Accountants, filed herewith.

    13   Purchase Agreement is incorporated by reference to Post-Effective
         Amendment No. 25 to the Registrant's Registration Statement on Form 
         N-1A (File Nos. 33-23166 and 811-5624), as filed with the SEC via 
         EDGAR on August 1, 1995.

    15   Form of Plan of Distribution Pursuant to Rule 12b-1 for Class B Shares
         (the "Class B Plan") of the Active Country Allocation Portfolio is
         incorporated by reference to Post-Effective Amendment No. 27 to the
         Registrant's Registration Statement on Form N-1A (File Nos. 33-23166
         and 811-5624), as filed with the SEC via EDGAR on November 1, 1995.
         The following Class B Plans have been omitted because they are
         substantially identical to the one filed herewith.  The omitted Class
         B Plans differ from the Class B Plan filed herewith only in references
         to the portfolio to which the Class B Plan relates:  Fixed Income,
         Global Fixed Income, Municipal Bond, Mortgage-Backed Securities, High
         Yield, Money Market, Municipal Money Market, Small Cap Value Equity,
         Value Equity, Balanced, Gold, Global Equity, International Equity,
         International Small Cap, Asian Equity, European Equity, Japanese
         Equity, Latin American, Emerging Markets, Emerging Markets Debt, China
         Growth, Equity Growth, Emerging Growth, MicroCap, Aggressive Equity,
         U.S. Real Estate and International Magnum Portfolios.

                                         C-3
    
<PAGE>
   
    16   Schedule of Computation of Performance Information is incorporated by
         reference to Post-Effective Amendment No. 25 to the Registrant's
         Registration Statement on Form N-1A (File Nos. 33-23166 and 811-5624),
         as filed with the SEC via EDGAR on August 1, 1995.

    19   Registrant's Rule 18F-3 Multiple Class Plan is incorporated by
         reference to Post-Effective Amendment No. 27 to the Registrant's
         Registration Statement on Form N-1A (File Nos. 33-23166 and 811-5624),
         as filed with the SEC via EDGAR on November 1, 1995.

    24   Powers of Attorney are incorporated by reference to Post-Effective
         Amendment No. 25 to the Registrant's Registration Statement on Form 
         N-1A (File Nos. 33-23166 and 811-5624), as filed with the SEC via 
         EDGAR on August 1, 1995.

    27   Financial Data Schedules for the fiscal year ended December 31, 1995
         for Registrant's portfolios in operation during such periods (See 
         Item 24(A)), filed herewith.

ITEM 25. PERSONS CONTROLLED BY OR UNDER COMMON CONTROL WITH REGISTRANT

         Registrant is not controlled by or under common control with any
         person.

ITEM 26. NUMBER OF HOLDERS OF SECURITIES (ON MARCH 29, 1996)

         Active Country Allocation Portfolio
              Class A........................................................63
              Class B........................................................28
         Aggressive Equity Portfolio
              Class A.......................................................114
              Class B........................................................67
         Asian Equity Portfolio
              Class A.......................................................928
              Class B.......................................................246
         Balanced Portfolio
              Class A........................................................53
              Class B........................................................63
         Emerging Growth Portfolio
              Class A.......................................................489
              Class B.......................................................158
         Emerging Markets Portfolio
              Class A......................................................1107
              Class B.......................................................236
         Equity Growth Portfolio
              Class A.......................................................498
              Class B.......................................................105
         Fixed Income Portfolio
              Class A.......................................................287
              Class B........................................................63
         Global Equity Portfolio
              Class A........................................................22
              Class B........................................................50
         Global Fixed Income Portfolio
              Class A........................................................88
              Class B........................................................52
         High Yield Portfolio
              Class A.......................................................381
              Class B........................................................68
         International Equity Portfolio
              Class A.......................................................308
              Class B.......................................................142

                                         C-4
    
<PAGE>
   
         International Small Cap Portfolio
              Class A.......................................................151
         Latin American Portfolio
              Class A.......................................................491
              Class B........................................................18
         Money Market Portfolio
              Class A.......................................................513
         Municipal Money Market Portfolio
              Class A.......................................................331
         Small Cap Value Equity Portfolio
              Class A.......................................................447
              Class B........................................................45
         U.S. Real Estate Portfolio
              Class A.......................................................479
              Class B........................................................55
         Value Equity Portfolio
              Class A.......................................................476
              Class B........................................................67
         European Equity Portfolio
              Class A.......................................................594
              Class B........................................................34
         Municipal Bond Portfolio
              Class A.......................................................109
              Class B.........................................................3
         Mortgage-Backed Securities Portfolio
              Class A.........................................................0
              Class B.........................................................0
         Japanese Equity Portfolio
              Class A.......................................................660
              Class B........................................................74
         Emerging Markets Debt Portfolio
              Class A.......................................................563
              Class B........................................................62
         Gold Portfolio
              Class A........................................................45
              Class B.........................................................9
         China Growth Portfolio
              Class A.........................................................0
              Class B.........................................................0
         MicroCap Portfolio
              Class A.........................................................0
              Class B.........................................................0
         International Magnum Portfolio
              Class A.........................................................3
              Class B.........................................................0
    
ITEM 27. INDEMNIFICATION

         Reference is made to Article TEN of the Registrant's Articles of
Incorporation.  Insofar as indemnification for liability arising under the
Securities Act of 1933 may be permitted to trustees, officers and controlling
persons of the registrant pursuant to the foregoing provisions, or otherwise,
the registrant has been advised that in the opinion of the Securities and
Exchange Commission such indemnification is against public policy as expressed
in the Act and is, therefore, unenforceable.  In the event that a claim for
indemnification against such liabilities (other than the payment by the
registrant of expenses incurred or paid by a trustee, officer or controlling
person of the registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the registrant will, unless in
the opinion of its counsel the matter has been settled by controlling precedent,
submit to a court of appropriate jurisdiction the question whether such
indemnification by it is against public policy as expressed in the Act and will
be governed by the final adjudication of such issue.

                                         C-5

<PAGE>

ITEM 28. BUSINESS AND OTHER CONNECTIONS WITH INVESTMENT ADVISER

         Reference is made to the caption "The Investment Adviser" in the
Prospectus constituting Part A of this Registration Statement and "Investment
Advisory Services" in Part B of Registration Statement.

         Listed below are the officers and Directors of Morgan Stanley Asset
Management Inc. ("MSAM").  The information as to any other business, profession,
vocation, or employment of substantial nature engaged in by the Chairman,
President and Directors during the past two fiscal years, is incorporated by
reference to Schedules A and D of Form ADV filed by MSAM pursuant to the
Advisers Act (SEC File No. 801-15757).
   

DIRECTORS:

James M. Allwin              Director
Barton M. Biggs              Director
Gordon S. Gray               Director
Peter A. Nadosy              Director
Dennis G. Sherva             Director

OFFICERS:

Barton M Biggs               Chairman
Peter A. Nadosy              Vice Chairman
James M. Allwin              President - Managing Director
Barton M. Biggs              Managing Director
P. Dominic Caldecott         Managing Director (MSAM) - UK
A. Macdonald Caputo          Managing Director
Ean Wah Chin                 Managing Director (MSAM) - Singapore
Garry B. Crowder             Managing Director
Michael A. Crowe             Managing Director
Madhav Dhar                  Managing Director
Kurt A. Feuerman             Managing Director
Gordon S. Gray               Managing Director
Gary D. Latainer             Managing Director
Peter A. Nadosy              Managing Director
Dennis G. Shorva             Managing Director
Richard G. Woolworth, Jr.    Managing Director
Warren Ackerman III          Principal
John R. Alkire               Principal (MSAM) - Tokyo
Robert E. Angevine           Principal
Gerald P. Barth-Wehrenalp    Principal
Francine J. Bovich           Principal
Stuart J. M. Breslow         Principal
Terence P. Carmichael        Principal
Arthur Certosimo             Principal
James K. K. Cheng            Principal (MSAM) - Singapore
Stephen C. Cordy             Principal
Jacqueline A. Day            Principal (MSAM) - UK
Paul B. Ghaffari             Principal
James Wayne Grisham          Principal
Perry E. Hall II             Principal
Marianne Laing Hay           Principal (MSAM) - UK
Margaret Kinsley Johnson     Principal
Kathryn Jonas Kasanoff       Principal
Debra A. F. Kushma           Principal
Marianne J. Lippamnn         Principal
Gary J. Mangino              Principal
M. Paul Martin               Principal
Walter Maynard, Jr.          Principal

                                         C-6
    
<PAGE>
   
Robert L. Meyer              Principal
Margaret P. Naylor           Principal (MSAM) - UK
Warren Olsen                 Principal
Christopher G. Petrow        Principal
Russell C. Platt             Principal
Gail Hunt Reeke              Principal
Christine I. Reilly          Principal
Bruce R. Sandberg            Principal
Robert A. Sargent            Principal (MSAM) - UK
Harold J. Schaaff, Jr.       Principal
Kiat Seng Scah               Principal (MSAM) - Singapore
Vinod R. Sethl               Principal
Stephen C. Sexauer           Principal
Robert M. Smith              Principal
Philip W. Winters            Principal
Alford E. Zick, Jr.          Principal
Marshall T. Bassett          Vice President
L. Kenneth Brooks            Vice President
Andrew C. Brown              Vice President (MSAM) - UK
Frances Campion              Vice President (MSAM) - UK
Carl Kuo-Wei Chien           Vice President (MSAM) - Hong Kong
Lori A. Cohane               Vice President
James Colmenares             Vice President
Kate Cornish-Bowden          Vice President (MSAM) - UK
Bertrand Le Pan De Ligny     Vice President (MSAM) - UK
Christine H. du Bois         Vice President
Raye L. Dube                 Vice President
Abigail Jones Feder          Vice President
Josephine M. Glass           Vice President
Maureen A. Grover            Vice President
Kenneth R. Holley            Vice President
Nan B. Levy                  Vice President
Valerie Y. Lewis             Vice President
Gordon W. Loory              Vice President
Yvonne Longley               Vice President (MSAM) - UK
Jeffrey Margolis             Vice President
Paula J. Morgan              Vice President (MSAM) - UK
Clare K. Mutone              Vice President
Martin O. Pearce             Vice President
Alexander A. Pena            Vice President
Anthony J. Pesce             Vice President
David J. Polansky            Vice President
Donald P. Ryan               Vice President
Michael James Smith          Vice President (MSAM) - UK
Kim I. Spellman              Vice President
Joseph P. Stadler            Vice President
Christian K. Stadlinger      Vice President
Catherine Steinhardt         Vice President
Kunihiko Sugio               Vice President (MSAM) - Tokyo
Joseph Y.S. Tern             Vice President (MSAM) - Singapore
Ann D. Thiviergo             Vice President
Richard Boon Hwee Toh        Vice President (MSAM) - Singapore
K.N. Vaidyanathan            Vice President (MSAM) - Bombay
Kevin V. Wasp                Vice President
Harold J. Schaaff, Jr.       General Counsel and Secretary
Madeline D. Barkhorn         Assistant Secretary
Charlene R. Herzer           Assistant Secretary
Charles R. Hintz             Treasurer

                                         C-7
    
<PAGE>
   
    In addition, MSAM acts as investment adviser to the following registered
investment companies:  American Advantage International Equity Fund; The
Brazilian Investment Fund, Inc.; certain portfolios of The Enterprise Group of
Funds, Inc.; Fountain Square International Equity Fund; General American Capital
Co.; The Latin American Discovery Fund, Inc., certain portfolios of The Legends
Fund, Inc.; The Malaysia Fund, Inc.; Morgan Stanley Africa Investment Fund,
Inc.; Morgan Stanley Asia-Pacific Fund, Inc.; Morgan Stanley Emerging Markets
Debt Fund, Inc.; Morgan Stanley Emerging Markets Fund, Inc.; all funds of the
Morgan Stanley Fund, Inc.; Morgan Stanley Global Opportunity Bond Fund, Inc.;
The Morgan Stanley High Yield Fund, Inc.; Morgan Stanley India Investment Fund,
Inc.; The Pakistan Investment Fund, Inc.;  PCS Cash Fund, Inc.; The Thai Fund,
Inc., The Turkish Investment Fund, Inc.; Principal Aggressive Growth Fund, Inc.;
Principal Asset Allocation Fund, Inc. and Sun America Series Trust.
    
ITEM 29.  PRINCIPAL UNDERWRITERS

    Morgan Stanley & Co. Incorporated ("MS&Co.") is distributor for Morgan
Stanley Institutional Fund, Inc., Morgan Stanley Fund, Inc. and PCS Cash Fund,
Inc.  The information required by this Item 29 with respect to each Director and
officer of MS&Co. is incorporated by reference to Schedule A of Form BD filed by
MS&Co. pursuant to the Securities and Exchange Act of 1934 (SEC File No. 
8-15869).

ITEM 30.  LOCATION OF ACCOUNTS AND RECORDS

    The books, accounts and other documents required by Section 31(a) under the
Investment Company Act of 1940 and the rules promulgated thereunder are
maintained in the physical possession of the Registrant; Registrant's Transfer
Agent, Chase Global Funds Services Company, P.O. Box 2798, Boston, Massachusetts
02208-2798; MSAM; MS&Co.; and the Registrant's custodian banks, including
sub-custodians.


ITEM 31.  MANAGEMENT SERVICES

    The Registrant has entered into a Service Agreement with The Chase
Manhattan Bank, N.A., successor in interest to United States Trust Company of
New York, which was filed as Exhibit No. 9(b) to Post-Effective Amendment No. 25
to the Fund's Registration Statement and is incorporated herein by reference.
   
ITEM 32.  UNDERTAKINGS

    1.  Registrant hereby undertakes to file a post-effective amendment
containing reasonably current financial statements, which need not be certified,
for the International Magnum and MicroCap Portfolios within four to six months
of their effective date or the commencement of operations, whichever is later.

    2.  Registrant hereby undertakes that whenever a Shareholder or
Shareholders who meet the requirements of Section 16(c) of the Investment
Company Act of 1940 inform the Board of Directors of his or their desire to
communicate with other Shareholders of the Fund, the Directors will inform such
Shareholder(s) as to the approximate number of Shareholders of record and the
approximate costs of mailing or afford said Shareholders access to a list of
Shareholders.
    
                                         C-8

<PAGE>

                                      SIGNATURES
   
         Pursuant to the requirements of the Securities Act of 1933 and the
Investment Company Act of 1940, the Registrant certifies that it meets all of
the requirements for effectiveness of this Amendment to its Registration
Statement pursuant to Rule 485(b) under the Securities Act of 1933 and has duly
caused this Amendment to its Registration Statement to be signed on its behalf
by the undersigned, thereunto duly authorized, in the City of New York and State
of New York, on April 25, 1996.
    
                   
                        MORGAN STANLEY INSTITUTIONAL FUND, INC.
   
                             By: /s/ WARREN J. OLSEN
                                ---------------------
    
                                  Warren J. Olsen
                                  President and Director

         Pursuant to the requirements of the Securities Act of 1933, this
amendment to the Registration Statement has been signed below by the following
persons in the capacities and on the dates indicated.

SIGNATURE                                     TITLE                    DATE
- ---------                                     -----                    ---- 
   
/S/ WARREN J. OLSEN                    Director, President       April 25, 1996
- -------------------                    (Principal Executive
Warren J. Olsen                        Officer)

*/S/ BARTON M. BIGGS                   Director (Chairman)       April 25, 1996
- -------------------
Barton M. Biggs

*/S/ FERGUS REID
- -------------------                    Director                  April 25, 1996
Fergus Reid

*/S/ FREDERICK O. ROBERTSHAW           Director                  April 25, 1996
- -------------------
Frederick O. Robertshaw

*/S/ ANDREW MCNALLY IV                 Director                  April 25, 1996
- -------------------
Andrew McNally IV

*/S/ JOHN D. BARRETT II                Director                  April 25, 1996
- -------------------
John D. Barrett II

*/S/ GERARD E. JONES                   Director                  April 25, 1996
- -------------------
Gerard E. Jones

*/S/ SAMUEL T. REEVES                  Director                  April 25, 1996
- -------------------
Samuel T. Reeves

*/S/ FREDERICK B. WHITTEMORE           Director                  April 25, 1996
- -------------------
Frederick B. Whittemore

*/S/ JAMES R. ROONEY                   Treasurer                 April 25, 1996
- ------------------                     (Principal
James R. Rooney                        Accounting
                                       Officer)

*By:/S/ WARREN J. OLSEN
    --------------------
     Warren J. Olsen
     Attorney-In-Fact
    
<PAGE>

                                    EXHIBIT INDEX
   
EDGAR
Exhibit
Number             Description

EX-99.B    1  Articles of Amendment and Restatement are incorporated by
              reference to Post-Effective Amendment No. 26 to the Registrant's
              Registration Statement on Form N-1A (File Nos. 33-23166 and 
              811-5624), as filed with the SEC via EDGAR on October 13, 1995.

EX-99.B    2  Amended and Restated By-laws are incorporated by reference to
              Post-Effective Amendment No. 25 to the Registrant's Registration
              Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
              filed with the SEC via EDGAR on August 1, 1995.

           4  Registrant's Form of Specimen Security was previously filed and is
              incorporated herein by reference.

EX-99.B    5  (a)  Investment Advisory Agreement between Registrant and Morgan
                   Stanley Asset Management Inc. is incorporated by reference
                   to Post-Effective Amendment No. 25 to the Registrant's
                   Registration Statement on Form N-1A (File Nos. 33-23166 and
                   811-5624), as filed with the SEC via EDGAR on August 1,
                   1995.

EX-99.B    5  (b)  Supplement to Investment Advisory Agreement between
                   Registrant and Morgan Stanley Asset Management Inc.  (adding
                   Registrant's Equity, Balanced and Fixed Income Portfolios)
                   is incorporated by reference to Post-Effective Amendment No.
                   25 to the Registrant's Registration Statement on Form N-1A
                   (File Nos. 33-23166 and 811-5624), as filed with the SEC via
                   EDGAR on August 1, 1995.

EX-99.B    5  (c)  Supplement to Investment Advisory Agreement between
                   Registrant and Morgan Stanley Asset Management Inc. (adding
                   the Global Equity, Global Fixed Income, European Equity and
                   Equity Growth Portfolios) is incorporated by reference to
                   Post-Effective Amendment No. 25 to the Registrant's
                   Registration Statement on Form N-1A (File Nos. 33-23166 and
                   811-5624), as filed with the SEC via EDGAR on August 1,
                   1995.

EX-99.B    5  (d)  Supplement to Investment Advisory Agreement between
                   Registrant and Morgan Stanley Asset Management Inc. (adding
                   the Asian Equity Portfolio) is incorporated by reference to
                   Post-Effective Amendment No. 25 to the Registrant's
                   Registration Statement on Form N-1A (File Nos. 33-23166 and
                   811-5624), as filed with the SEC via EDGAR on August 1,
                   1995.

EX-99.B    5  (e)  Supplement to Investment Advisory Agreement between
                   Registrant and Morgan Stanley Asset Management Inc. (adding
                   the Active Country Allocation Portfolio) is incorporated by
                   reference to Post-Effective Amendment No. 25 to the
                   Registrant's Registration Statement on Form N-1A (File Nos.
                   33-23166 and 811-5624), as filed with the SEC via EDGAR on
                   August 1, 1995.
    
<PAGE>
   
EX-99.B    5  (f)  Supplement to Investment Advisory Agreement between
                   Registrant and Morgan Stanley Asset Management Inc. (adding
                   the Emerging Markets, High Yield and International Small Cap
                   Portfolios) is incorporated by reference to Post-Effective
                   Amendment No. 25 to the Registrant's Registration Statement
                   on Form N-1A (File Nos. 33-23166 and 811-5624), as filed
                   with the SEC via EDGAR on August 1, 1995.

EX-99.B    5  (g)  Supplement to Investment Advisory Agreement between
                   Registrant and Morgan Stanley Asset Management Inc. (adding
                   the Small Cap Value Equity Portfolio) is incorporated by
                   reference to Post-Effective Amendment No. 25 to the
                   Registrant's Registration Statement on Form N-1A (File Nos.
                   33-23166 and 811-5624), as filed with the SEC via EDGAR on
                   August 1, 1995.

EX-99.B    5  (h)  Supplement to Investment Advisory Agreement between
                   Registrant and Morgan Stanley Asset Management Inc. (adding
                   the Emerging Markets Debt, Mortgage-Backed Securities,
                   Municipal Bond and Japanese Equity Portfolios) is
                   incorporated by reference to Post-Effective Amendment No. 25
                   to the Registrant's Registration Statement on Form N-1A
                   (File Nos. 33-23166 and 811-5624), as filed with the SEC via
                   EDGAR on August 1, 1995.

EX-99.B    5  (i)  Sub-Advisory Agreement among Registrant, Morgan Stanley
                   Asset Management Inc. and Sun Valley Gold Company (with
                   respect to the Gold Portfolio) is incorporated by reference
                   to Post-Effective Amendment No. 25 to the Registrant's
                   Registration Statement on Form N-1A (File Nos. 33-23166 and
                   811-5624), as filed with the SEC via EDGAR on August 1,
                   1995.

EX-99.B    5  (j)  Supplement to Investment Advisory Agreement between
                   Registrant and Morgan Stanley Asset Management Inc. (adding
                   the China Growth Portfolio) is incorporated by reference to
                   Post-Effective Amendment No. 25 to the Registrant's
                   Registration Statement on Form N-1A (File Nos. 33-23166 and
                   811-5624), as filed with the SEC via EDGAR on August 1,
                   1995.

EX-99.B    5  (k)  Supplement to Investment Advisory Agreement between
                   Registrant and Morgan Stanley Asset Management Inc. (adding
                   the Latin American Portfolio) is incorporated by reference
                   to Post-Effective Amendment No. 25 to the Registrant's
                   Registration Statement on Form N-1A (File Nos. 33-23166 and
                   811-5624), as filed with the SEC via EDGAR on August 1,
                   1995.

EX-99.B    5  (l)  Supplement to Investment Advisory Agreement between
                   Registrant and Morgan Stanley Asset Management Inc. (adding
                   the Contrarian Portfolio) is incorporated by reference to
                   Post-Effective Amendment No. 25 to the Registrant's
                   Registration Statement on Form N-1A (File Nos. 33-23166 and
                   811-5624), as filed with the SEC via EDGAR on August 1,
                   1995.

EX-99.B    5  (m)  Supplement to Investment Advisory Agreement between
                   Registrant and Morgan Stanley Asset Management Inc. (adding
                   the Aggressive Equity and U.S. Real Estate Portfolios) is
                   incorporated by reference to Post-Effective Amendment No. 25
                   to the Registrant's Registration Statement

                                          2
    
<PAGE>
   
                   on Form N-1A (File Nos. 33-23166 and 811-5624), as filed
                   with the SEC via EDGAR on August 1, 1995.

EX-99.B    5  (n)  Supplement to Investment Advisory Agreement between
                   Registrant and Morgan Stanley Asset Management, Inc. (adding
                   the MicroCap Portfolio) is incorporated by reference to
                   Post-Effective Amendment No. 25 to the Registrant's
                   Registration Statement on Form N-1A (File Nos. 33-23166 and
                   811-5624), as filed with the SEC via EDGAR on August 1,
                   1995.

EX-99.B    5  (o)  Supplement to Investment Advisory Agreement between
                   Registrant and Morgan Stanley Asset Management, Inc. (adding
                   the International Magnum Portfolio) is incorporated by
                   reference to Post-Effective Amendment No. 28 to the
                   Registrant's Registration Statement on Form N-1A (File Nos.
                   33-23166 and 811-5624), as filed with the SEC via EDGAR on
                   November 3, 1995.

EX-99.B    6  (a)  Distribution Agreement between Registrant and Morgan Stanley
                   & Co. Incorporated is incorporated by reference to Post-
                   Effective Amendment No. 25 to the Registrant's Registration
                   Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
                   filed with the SEC via EDGAR on August 1, 1995.

EX-99.B    6  (b)  Supplement to Distribution Agreement between Registrant and
                   Morgan Stanley & Co. Incorporated, filed herewith.

EX-99.B    8  (a)  Mutual Fund Custody Agreement (Domestic Custody Agreement)
                   between Registrant and United States Trust Company of New
                   York dated March 10, 1994 is incorporated by reference to
                   Post-Effective Amendment No. 25 to the Registrant's
                   Registration Statement on Form N-1A (File Nos. 33-23166 and
                   811-5624), as filed with the SEC via EDGAR on August 1,
                   1995.

EX-99.B    8  (b)  Registrant's Custody Agreement (International), dated July
                   31, 1989, as amended on [_____________, 1995] is
                   incorporated by reference to Post-Effective Amendment No. 25
                   to the Registrant's Registration Statement on Form N-1A
                   (File Nos. 33-23166 and 811-5624), as filed with the SEC via
                   EDGAR on August 1, 1995.

EX-99.B    9  (a)  Administration Agreement between Registrant and Morgan
                   Stanley Asset Management Inc. (the "MSAM Administration
                   Agreement") is incorporated by reference to Post-Effective
                   Amendment No. 25 to the Registrant's Registration Statement
                   on Form N-1A (File Nos. 33-23166 and 811-5624), as filed
                   with the SEC via EDGAR on August 1, 1995.

EX-99.B   9   (b)  U.S. Trust Administration Agreement is incorporated by
                   reference to Post-Effective Amendment No. 25 to the
                   Registrant's Registration Statement on Form N-1A (File Nos.
                   33-23166 and 811-5624), as filed with the SEC via EDGAR on
                   August 1, 1995.

EX-99.B   10       Opinion of Counsel is incorporated by reference to Post-
                   Effective Amendment No. 25 to the Registrant's Registration
                   Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
                   filed with the SEC via EDGAR on August 1, 1995.

                                          3
    
<PAGE>
   
EX-99.B   11       Consent of Independent Accountants, filed herewith.

EX-99.B   13       Purchase Agreement is incorporated by reference to Post-
                   Effective Amendment No. 25 to the Registrant's Registration
                   Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
                   filed with the SEC via EDGAR on August 1, 1995.

EX-99.B   15       Form of Plan of Distribution Pursuant to Rule 12b-1 for
                   Class B Shares (the "Class B Plan") of the Active Country
                   Allocation Portfolio is incorporated by reference to Post-
                   Effective Amendment No. 27 to the Registrant's Registration
                   Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
                   filed with the SEC via EDGAR on November 1, 1995.  The
                   following Class B Plans have been omitted because they are
                   substantially identical to the one filed herewith.  The
                   omitted Class B Plans differ from the Class B Plan filed
                   herewith only in references to the portfolio to which the
                   Class B Plan relates:  Fixed Income, Global Fixed Income,
                   Municipal Bond, Mortgage-Backed Securities, High Yield,
                   Money Market, Municipal Money Market, Small Cap Value
                   Equity, Value Equity, Balanced, Gold, Global Equity,
                   International Equity, International Small Cap, Asian Equity,
                   European Equity, Japanese Equity, Latin American, Emerging
                   Markets, Emerging Markets Debt, China Growth, Equity Growth,
                   Emerging Growth, MicroCap, Aggressive Equity, U.S. Real
                   Estate and International Magnum Portfolios.

EX-99.B   16       Schedule of Computation of Performance Information is
                   incorporated by reference to Post-Effective Amendment No. 25
                   to the Registrant's Registration Statement on Form N-1A
                   (File Nos. 33-23166 and 811-5624), as filed with the SEC via
                   EDGAR on August 1, 1995.

EX-99.B   19       Registrant's Rule 18F-3 Multiple Class Plan is incorporated
                   by reference to Post-Effective Amendment No. 27 to the
                   Registrant's Registration Statement on Form N-1A (File Nos.
                   33-23166 and 811-5624), as filed with the SEC via EDGAR on
                   November 1, 1995.

EX-99.B   24       Powers of Attorney are incorporated by reference to Post-
                   Effective Amendment No. 25 to the Registrant's Registration
                   Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
                   filed with the SEC via EDGAR on August 1, 1995.

EX-99.B   27       Financial Data Schedules for the fiscal year ended December
                   31, 1995 for Registrant's portfolios in operation during such
                   periods (See Item 24(A)), filed herewith.

                                          4
    

<PAGE>
                                                                   EXHIBIT 6(b)

                         SUPPLEMENT TO DISTRIBUTION AGREEMENT
                                          OF
                       MORGAN STANLEY INSTITUTIONAL FUND, INC.

                                   (CLASS B SHARES)

              Supplement dated as of December 18, 1995, (the "Supplement") to
Distribution Agreement dated as of October 1, 1988 (the "Agreement") among
Morgan Stanley Institutional Fund, Inc., a Maryland corporation (the "Fund"),
and Morgan Stanley & Co. Incorporated, a Delaware corporation (the
"Distributor").

                                       RECITALS

              The Fund has executed and delivered a Distribution Agreement,
dated as of October 1, 1988, between the Fund and the Distributor.  The
Agreement appoints the Distributor in connection with the offering and sale of
the shares of common stock, par value $0.001, of the Fund and sets forth the
rights and obligations of the parties with respect to the distribution of the
shares.

                                      AGREEMENTS

              NOW, therefore, the parties agree that the rights and obligations
set forth in the Distribution Agreement shall be applicable to the Class B
Shares of the Fund and that with respect to such shares, the Agreement is
amended and supplemented by the following:

              COMPENSATION

                   For the services to be rendered and the expenses assumed by
              the Distributor with respect to the Class B Shares, the Fund
              shall pay to the Distributor, compensation at the annual rate of
              .25% of the average daily net assets of the Class B Shares.
              Except as hereinafter set forth, continuing compensation under
              this Agreement shall be calculated and accrued daily and the
              amounts of the daily accruals shall be paid monthly in arrears
              within ten days after the end of the month.  If this Agreement
              becomes effective subsequent to the first day of a month or shall
              terminate before the last day of a month, compensation for that
              part of the month this Agreement is in effect shall be prorated
              in a manner consistent with the calculations of the fees as set
              forth above.  Payment of the Distributor's compensation for the
              preceding month shall be made as promptly as possible, but in no
              event later than ten days after the end of the month.

              This Supplement may be executed in any number of counterparts,
each of which so executed shall be deemed to be an original, but all such
counterparts shall together constitute but one and the same instrument.

              The parties listed below have executed this Supplement as of
December 18, 1995.

                                       MORGAN STANLEY & CO. INCORPORATED


                                       By: /s/ Warren J. Olsen
                                           ------------------------------------
                                       Name:
                                       Title: Principal

                                       MORGAN STANLEY INSTITUTIONAL FUND, INC.

                                       By: /s/ Warren J. Olsen
                                           ------------------------------------
                                       Name:
                                       Title: Director and President


<PAGE>

                      CONSENT OF INDEPENDENT ACCOUNTANTS

We hereby consent to the use in the Statement of Additional Information 
constituting part of this Post-Effective Amendment No. 29 to the registration 
on Form N-1A (the "Registration Statement") of our report dated February 9, 
1996, relating to the financial statements and financial highlights of Morgan 
Stanley Institutional Fund, Inc., which appears in such Statement of 
Additional Information, and the incorporation by reference of our report into 
the Prospectuses which constitute parts of this Registration Statement. We 
also consent to the references to us under the heading "Financial Statements" 
in such Statement of Additional Information and the references to us under 
the headings "Financial Highlights", where applicable, and "Independent 
Accountants" in such Prospectuses.


PRICE WATERHOUSE LLP
1177 Avenue of the Americas
New York, New York 10036
April 22, 1996

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 14
   <NAME> ACTIVE COUNTRY ALLOCATION PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
<FISCAL-YEAR-END>                          DEC-31-1995
<PERIOD-START>                             JAN-01-1995
<PERIOD-END>                               DEC-31-1995
<INVESTMENTS-AT-COST>                          149,711
<INVESTMENTS-AT-VALUE>                         160,656
<RECEIVABLES>                                      857
<ASSETS-OTHER>                                      14
<OTHER-ITEMS-ASSETS>                             9,417
<TOTAL-ASSETS>                                 170,944
<PAYABLE-FOR-SECURITIES>                          (23)
<SENIOR-LONG-TERM-DEBT>                              0
<OTHER-ITEMS-LIABILITIES>                        (258)
<TOTAL-LIABILITIES>                              (281)
<SENIOR-EQUITY>                                      0
<PAID-IN-CAPITAL-COMMON>                       157,244
<SHARES-COMMON-STOCK>                           14,673
<SHARES-COMMON-PRIOR>                           15,712
<ACCUMULATED-NII-CURRENT>                            0
<OVERDISTRIBUTION-NII>                         (7,782)
<ACCUMULATED-NET-GAINS>                            838
<OVERDISTRIBUTION-GAINS>                             0
<ACCUM-APPREC-OR-DEPREC>                        20,363
<NET-ASSETS>                                   170,663
<DIVIDEND-INCOME>                                3,211
<INTEREST-INCOME>                                  179
<OTHER-INCOME>                                       0
<EXPENSES-NET>                                 (1,316)
<NET-INVESTMENT-INCOME>                          2,074
<REALIZED-GAINS-CURRENT>                       (1,123)
<APPREC-INCREASE-CURRENT>                       15,675
<NET-CHANGE-FROM-OPS>                           16,626
<EQUALIZATION>                                       0
<DISTRIBUTIONS-OF-INCOME>                      (4,800)
<DISTRIBUTIONS-OF-GAINS>                      (12,502)
<DISTRIBUTIONS-OTHER>                                0
<NUMBER-OF-SHARES-SOLD>                          7,883
<NUMBER-OF-SHARES-REDEEMED>                   (10,268)
<SHARES-REINVESTED>                              1,346
<NET-CHANGE-IN-ASSETS>                        (12,314)
<ACCUMULATED-NII-PRIOR>                          1,418
<ACCUMULATED-GAINS-PRIOR>                        7,989
<OVERDISTRIB-NII-PRIOR>                              0
<OVERDIST-NET-GAINS-PRIOR>                           0
<GROSS-ADVISORY-FEES>                            1,068
<INTEREST-EXPENSE>                                   0
<GROSS-EXPENSE>                                  1,934
<AVERAGE-NET-ASSETS>                           164,600
<PER-SHARE-NAV-BEGIN>                            11.65
<PER-SHARE-NII>                                   0.17
<PER-SHARE-GAIN-APPREC>                           1.00
<PER-SHARE-DIVIDEND>                            (0.35)    
<PER-SHARE-DISTRIBUTIONS>                       (0.84) 
<RETURNS-OF-CAPITAL>                                 0      
<PER-SHARE-NAV-END>                              11.63
<EXPENSE-RATIO>                                   0.80
<AVG-DEBT-OUTSTANDING>                               0
<AVG-DEBT-PER-SHARE>                                 0
        


</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 12
   <NAME> ASIAN EQUITY PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
<FISCAL-YEAR-END>                          DEC-31-1995
<PERIOD-START>                             JAN-01-1995
<PERIOD-END>                               DEC-31-1995
<INVESTMENTS-AT-COST>                          270,840
<INVESTMENTS-AT-VALUE>                         313,770
<RECEIVABLES>                                    3,696
<ASSETS-OTHER>                                      23
<OTHER-ITEMS-ASSETS>                                 0
<TOTAL-ASSETS>                                 317,489
<PAYABLE-FOR-SECURITIES>                           427
<SENIOR-LONG-TERM-DEBT>                              0
<OTHER-ITEMS-LIABILITIES>                        2,178
<TOTAL-LIABILITIES>                              2,605
<SENIOR-EQUITY>                                      0
<PAID-IN-CAPITAL-COMMON>                       268,221
<SHARES-COMMON-STOCK>                           16,166
<SHARES-COMMON-PRIOR>                           12,854
<ACCUMULATED-NII-CURRENT>                            0
<OVERDISTRIBUTION-NII>                             (3)
<ACCUMULATED-NET-GAINS>                          3,738
<OVERDISTRIBUTION-GAINS>                             0
<ACCUM-APPREC-OR-DEPREC>                        42,928
<NET-ASSETS>                                   314,884
<DIVIDEND-INCOME>                                4,990
<INTEREST-INCOME>                                  711
<OTHER-INCOME>                                       0
<EXPENSES-NET>                                 (2,905)
<NET-INVESTMENT-INCOME>                          2,796
<REALIZED-GAINS-CURRENT>                        12,459
<APPREC-INCREASE-CURRENT>                        7,852
<NET-CHANGE-FROM-OPS>                           23,107
<EQUALIZATION>                                       0
<DISTRIBUTIONS-OF-INCOME>                      (4,869)
<DISTRIBUTIONS-OF-GAINS>                      (40,469)
<DISTRIBUTIONS-OTHER>                                0
<NUMBER-OF-SHARES-SOLD>                         24,613
<NUMBER-OF-SHARES-REDEEMED>                   (23,439)
<SHARES-REINVESTED>                              2,138
<NET-CHANGE-IN-ASSETS>                          37,978
<ACCUMULATED-NII-PRIOR>                          1,886
<ACCUMULATED-GAINS-PRIOR>                       32,350
<OVERDISTRIB-NII-PRIOR>                              0
<OVERDIST-NET-GAINS-PRIOR>                           0
<GROSS-ADVISORY-FEES>                            2,301
<INTEREST-EXPENSE>                                   0
<GROSS-EXPENSE>                                  3,427
<AVERAGE-NET-ASSETS>                           287,937
<PER-SHARE-NAV-BEGIN>                            21.54
<PER-SHARE-NII>                                   0.18
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 13
   <NAME> EMERGING MARKETS PORTFOLIO
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 9
   <NAME> EUROPEAN EQUITY PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 8
   <NAME> GLOBAL EQUITY PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
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<PERIOD-START>                             JAN-01-1995
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 19
   <NAME> GOLD PORTFOLIO
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 4
   <NAME> INTERNATIONAL EQUITY PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
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<PERIOD-START>                             JAN-01-1995
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<NUMBER-OF-SHARES-REDEEMED>                    (8,961)
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<PER-SHARE-DIVIDEND>                            (0.06)     
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 15
   <NAME> INTERNATIONAL SMALL CAP PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
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<PERIOD-END>                               DEC-31-1995
<INVESTMENTS-AT-COST>                          208,494
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 20
   <NAME> JAPANESE EQUITY PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 25
   <NAME> LATIN AMERICAN PORTFOLIO
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 27
   <NAME> AGGRESSIVE EQUITY PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 3
   <NAME> EMERGING GROWTH PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 11
   <NAME> EQUITY GROWTH PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
<FISCAL-YEAR-END>                          DEC-31-1995
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<PER-SHARE-NAV-BEGIN>                            12.02
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<EXPENSE-RATIO>                                   0.80
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<AVG-DEBT-PER-SHARE>                                 0
        


</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 17
   <NAME> SMALL CAP VALUE EQUITY PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
<FISCAL-YEAR-END>                          DEC-31-1995
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 26
   <NAME> U.S. REAL ESTATE PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   OTHER
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 5
   <NAME> VALUE EQUITY PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
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<PERIOD-START>                             JAN-01-1995
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 6
   <NAME> BALANCED PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
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<AVG-DEBT-PER-SHARE>                                 0
        


</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 21
   <NAME> EMERGING MARKETS DEBT PORTFOLIO
   <MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
<FISCAL-YEAR-END>                          DEC-31-1995
<PERIOD-START>                             JAN-01-1995
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<NUMBER-OF-SHARES-REDEEMED>                   (17,651)
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<PER-SHARE-NAV-BEGIN>                             8.59
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<RETURNS-OF-CAPITAL>                                 0
<PER-SHARE-NAV-END>                               8.59
<EXPENSE-RATIO>                                   1.75
<AVG-DEBT-OUTSTANDING>                               0
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 7
   <NAME> FIXED INCOME PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
<FISCAL-YEAR-END>                          DEC-31-1995
<PERIOD-START>                             JAN-01-1995
<PERIOD-END>                               DEC-31-1995
<INVESTMENTS-AT-COST>                          155,014
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<OVERDISTRIBUTION-NII>                               0
<ACCUMULATED-NET-GAINS>                        (8,331)
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<DIVIDEND-INCOME>                                    0
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<NUMBER-OF-SHARES-SOLD>                          6,668
<NUMBER-OF-SHARES-REDEEMED>                   (13,696)
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<NET-CHANGE-IN-ASSETS>                        (43,804)
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<PER-SHARE-NAV-END>                              10.81
<EXPENSE-RATIO>                                   0.45
<AVG-DEBT-OUTSTANDING>                               0
<AVG-DEBT-PER-SHARE>                                 0
        


</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 10
   <NAME> GLOBAL FIXED INCOME PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
<FISCAL-YEAR-END>                          DEC-31-1995
<PERIOD-START>                             JAN-01-1995
<PERIOD-END>                               DEC-31-1995
<INVESTMENTS-AT-COST>                          109,280
<INVESTMENTS-AT-VALUE>                         112,666
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<OVERDISTRIBUTION-NII>                               0
<ACCUMULATED-NET-GAINS>                        (7,109)                       
<OVERDISTRIBUTION-GAINS>                             0
<ACCUM-APPREC-OR-DEPREC>                         3,529
<NET-ASSETS>                                   102,852
<DIVIDEND-INCOME>                                    0
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<NUMBER-OF-SHARES-SOLD>                          3,346
<NUMBER-OF-SHARES-REDEEMED>                    (7,623)
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<EXPENSE-RATIO>                                   0.50
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<AVG-DEBT-PER-SHARE>                                 0
        


</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 16
   <NAME> HIGH YIELD PORTFOLIO
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<S>                             <C>
<PERIOD-TYPE>                   12-MOS
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<PERIOD-START>                             JAN-01-1995
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<OVERDISTRIBUTION-NII>                               0
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<OVERDISTRIBUTION-GAINS>                             0
<ACCUM-APPREC-OR-DEPREC>                         (767)
<NET-ASSETS>                                    62,245
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<INTEREST-INCOME>                                7,927
<OTHER-INCOME>                                       0
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<NET-CHANGE-FROM-OPS>                           14,218
<EQUALIZATION>                                       0
<DISTRIBUTIONS-OF-INCOME>                      (8,122)
<DISTRIBUTIONS-OF-GAINS>                             0   
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<NUMBER-OF-SHARES-SOLD>                          5,865
<NUMBER-OF-SHARES-REDEEMED>                   (10,704)
<SHARES-REINVESTED>                                609
<NET-CHANGE-IN-ASSETS>                        (34,978)
<ACCUMULATED-NII-PRIOR>                            731
<ACCUMULATED-GAINS-PRIOR>                      (1,581)
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<OVERDIST-NET-GAINS-PRIOR>                           0
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<INTEREST-EXPENSE>                                   0
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<AVERAGE-NET-ASSETS>                            67,393
<PER-SHARE-NAV-BEGIN>                             9.55
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<EXPENSE-RATIO>                                   0.75
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<AVG-DEBT-PER-SHARE>                                 0
        


</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 23
   <NAME> MUNICIPAL BOND PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   OTHER
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<NUMBER-OF-SHARES-REDEEMED>                    (1,912)
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<PER-SHARE-NAV-BEGIN>                            10.00
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 1
   <NAME> MONEY MARKET PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
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<PERIOD-END>                               DEC-31-1995
<INVESTMENTS-AT-COST>                          836,431
<INVESTMENTS-AT-VALUE>                         836,431
<RECEIVABLES>                                    2,802
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<TOTAL-LIABILITIES>                              2,598
<SENIOR-EQUITY>                                      0
<PAID-IN-CAPITAL-COMMON>                       836,706
<SHARES-COMMON-STOCK>                          836,710
<SHARES-COMMON-PRIOR>                          690,597
<ACCUMULATED-NII-CURRENT>                            0
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<OVERDISTRIBUTION-GAINS>                             0
<ACCUM-APPREC-OR-DEPREC>                             0
<NET-ASSETS>                                   836,693
<DIVIDEND-INCOME>                                    0
<INTEREST-INCOME>                               48,910
<OTHER-INCOME>                                       0
<EXPENSES-NET>                                 (4,253)
<NET-INVESTMENT-INCOME>                         44,657
<REALIZED-GAINS-CURRENT>                            79
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<EQUALIZATION>                                       0
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<NUMBER-OF-SHARES-SOLD>                      8,093,987
<NUMBER-OF-SHARES-REDEEMED>                (7,989,639)
<SHARES-REINVESTED>                             41,765
<NET-CHANGE-IN-ASSETS>                         146,190
<ACCUMULATED-NII-PRIOR>                              0
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<OVERDISTRIB-NII-PRIOR>                              0
<OVERDIST-NET-GAINS-PRIOR>                           0
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<AVERAGE-NET-ASSETS>                           831,489
<PER-SHARE-NAV-BEGIN>                            1.000
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<PER-SHARE-DIVIDEND>                           (0.054)
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<PER-SHARE-NAV-END>                              1.000
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 2
   <NAME> MUNICIPAL MONEY MARKET PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
<FISCAL-YEAR-END>                          DEC-31-1995
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<PERIOD-END>                               DEC-31-1995
<INVESTMENTS-AT-COST>                          450,017
<INVESTMENTS-AT-VALUE>                         450,017
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<SENIOR-EQUITY>                                      0
<PAID-IN-CAPITAL-COMMON>                       451,528
<SHARES-COMMON-STOCK>                          451,502
<SHARES-COMMON-PRIOR>                          359,426
<ACCUMULATED-NII-CURRENT>                            0
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<DIVIDEND-INCOME>                                    0
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<REALIZED-GAINS-CURRENT>                           (1)
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<EQUALIZATION>                                       0
<DISTRIBUTIONS-OF-INCOME>                     (13,579)
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<NUMBER-OF-SHARES-SOLD>                      3,169,110
<NUMBER-OF-SHARES-REDEEMED>                (3,090,216)
<SHARES-REINVESTED>                             13,182
<NET-CHANGE-IN-ASSETS>                          92,075
<ACCUMULATED-NII-PRIOR>                              0
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<PER-SHARE-NAV-BEGIN>                            1.000
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</TABLE>


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