MORGAN STANLEY INSTITUTIONAL FUND INC
N-30B-2, 1996-06-07
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<PAGE>
- --------------------------------------------------
OFFICERS AND DIRECTORS
 
Barton M. Biggs             James W. Grisham
  CHAIRMAN OF THE BOARD     VICE PRESIDENT
Frederick B. Whittemore     Michael F. Klein
  VICE-CHAIRMAN OF THE      VICE PRESIDENT
BOARD                       Harold J. Schaaff, Jr.
Warren J. Olsen             VICE PRESIDENT
  PRESIDENT AND DIRECTOR    Joseph P. Stadler
John D. Barrett II          VICE PRESIDENT
  DIRECTOR                  Valerie Y. Lewis
Gerard E. Jones             SECRETARY
  DIRECTOR                  Karl O. Hartmann
Andrew McNally, IV          ASSISTANT SECRETARY
  DIRECTOR                  James R. Rooney
Samuel T. Reeves            TREASURER
  DIRECTOR                  Joanna M. Haigney
Fergus Reid                 ASSISTANT TREASURER
  DIRECTOR
Frederick O. Robertshaw
  DIRECTOR
 
- --------------------------------------------------
INVESTMENT ADVISER AND ADMINISTRATOR
Morgan Stanley Asset Management Inc.
1221 Avenue of the Americas
New York, New York 10020
- --------------------------------------------------
DISTRIBUTOR
Morgan Stanley & Co. Incorporated
1251 Avenue of the Americas
New York, New York 10020
- --------------------------------------------------
CUSTODIANS
The Chase Manhattan Bank, N.A.
770 Broadway
New York, New York 10003
 
Morgan Stanley Trust Company
One Pierrepont Plaza
Brooklyn, New York 11210
- --------------------------------------------------
LEGAL COUNSEL
Morgan, Lewis & Bockius LLP
2000 One Logan Square
Philadelphia, Pennsylvania 19103
- --------------------------------------------------
INDEPENDENT ACCOUNTANTS
Price Waterhouse LLP
1177 Avenue of the Americas
New York, New York 10036
 
- --------------------------------------------------
For current performance, current net asset value, or for assistance with your
account, please contact the Fund at (800) 548-7786. This report is authorized
for distribution only when preceded or accompanied by prospectuses of the Morgan
Stanley Institutional Fund, Inc.
 
[LOGO] MORGAN STANLEY
       INSTITUTIONAL FUND, INC.
       P.O. Box 2798
       Boston, MA 02208-2798
 
[LOGO] MORGAN STANLEY
       INSTITUTIONAL FUND, INC.
 
                          AGGRESSIVE EQUITY PORTFOLIO
                              FIRST QUARTER REPORT
                                 MARCH 31, 1996
<PAGE>
LETTER TO SHAREHOLDERS
- -------
 
The  Aggressive Equity Portfolio seeks  long-term capital appreciation through a
concentrated, non-diversified portfolio of  U.S. equity securities. Short  sales
and  options can be used to enhance  performance, although this strategy was not
being utilized  at March  31. It  is anticipated  that the  Portfolio will  hold
thirty  names or less, although it may hold more from time to time. At March 31,
1996, there were 33 positions in the Portfolio and three small call positions to
augment our exposure to two portfolio names.
 
For the three  month period  ended March  31, 1996,  the Portfolio  had a  total
return  of 11.75% for the Class  A shares and 10.94% for  the Class B shares, as
compared to a total  return of 5.53% for  the Lipper Capital Appreciation  Index
and  5.36% for the S&P  500 Index for the same  period. The average annual total
return for  the twelve  months ended  March 31,  1996 and  for the  period  from
inception  on  March  8, 1995  through  March  31, 1996  was  51.92%  and 53.45%
respectively  for  the  Class  A  shares,  as  compared  to  29.00%  and  30.44%
respectively  for the Lipper  Capital Appreciation Index  and 32.07% and 34.50%,
respectively for the S&P 500 Index.
 
PERFORMANCE COMPARED TO THE  LIPPER CAPITAL APPRECIATION INDEX  AND THE S&P  500
INDEX(1)
- ----------------------------------------------------
 
<TABLE>
<CAPTION>
                                               TOTAL RETURNS(2)
                                    ---------------------------------------
                                                  ONE      AVERAGE ANNUAL
                                       YTD       YEAR      SINCE INCEPTION
                                    ---------  ---------  -----------------
<S>                                 <C>        <C>        <C>
PORTFOLIO--CLASS A................      11.75%     51.92%         53.45%
PORTFOLIO--CLASS B(3).............      10.94        N/A            N/A
LIPPER CAPITAL APPRECIATION
 INDEX............................       5.53      29.00          30.44
S&P 500 INDEX.....................       5.36      32.07          34.50
</TABLE>
 
1.  The Lipper Capital Appreciation Index is a composite of mutual funds managed
    for maximum capital gains. The S&P 500 Index is an unmanaged index of common
    stocks.
 
2.  Total  returns for the Portfolio reflect  expenses waived and reimbursed, if
    applicable, by the  Adviser. Without  such waiver  and reimbursement,  total
    returns would be lower.
 
3.  The Portfolio began offering Class B shares on January 2, 1996.
 
PAST PERFORMANCE IS NOT PREDICTIVE OF FUTURE PERFORMANCE.
- ------------------------------
THE  PERFORMANCE RESULTS PROVIDED ARE FOR INFORMATIONAL PURPOSES ONLY AND SHOULD
NOT BE CONSTRUED  AS A  GUARANTEE OF  THE PORTFOLIO'S  FUTURE PERFORMANCE.  PAST
PERFORMANCE SHOWN IS NOT PREDICTIVE OF FUTURE PERFORMANCE. INVESTMENT RETURN AND
PRINCIPAL  VALUE WILL FLUCTUATE SO THAT AN INVESTOR'S SHARES, WHEN REDEEMED, MAY
BE WORTH MORE OR LESS THAN THEIR ORIGINAL COST.
 
We made two strategic shifts during the quarter, one a reduction of exposure  in
finance and the other, an increase in exposure to tobacco. In December and early
January we had built up our exposure to the financial names, largely through our
position  in Wells Fargo. Financials, in general,  had been weak from October of
1995 through about year-end as fears of rising consumer debt delinquency spooked
investors. We  added to  our position  in Wells  Fargo in  the belief  that  the
company's growth initiatives--restructuring the business to focus on fee income,
reducing  costs, buying back shares, not to mention the potential acquisition of
First Interstate-- would produce excellent  shareholder returns. The stock  rose
about 21% in the first quarter and we have subsequently trimmed it and our other
financial  holdings to reflect  the powerful upward  move in the  stocks and the
spike up in interest rates.
 
During the month of March tobacco stocks came under renewed attack in the market
in the wake of new litigation fears.  Like the financials in the fourth  quarter
of  1995, however, earnings estimates for the tobacco stocks held steady or rose
during this  rocky  period. Our  largest  tobacco-related holding  (and  biggest
single  position) is Philip Morris, which we  raised to about an 18% position at
the end of March.  We added to  the stock because  the fundamentals remain  very
strong--earnings  are growing at  about a 17%  rate, the yield  is a substantial
4.6%, and the company is retiring 4% of its shares per year. Valuation (which is
of secondary importance to  us) is also compelling  at 9.9 times 1997  estimates
versus  15.6 times for the S&P 500. Finally, we expect the dividend to be raised
to $4.80 this August and $5.60 in  August, 1997, which suggests the stock  could
move from its current price of approximately $90 to $120 in 12-18 months.
 
Other  important holdings include Loews Corporation, HFS, Boston Chicken, United
Technologies and Ralston Purina. We ended the quarter with approximately 10%  in
cash.  This  was  less a  "market  call"  than the  residual  of  our day-to-day
investment process and we expect to put the cash to work shortly.
 
Kurt Feuerman
PORTFOLIO MANAGER
April 1996
 
                                       2
<PAGE>
INVESTMENTS (UNAUDITED)
- ----------
MARCH 31, 1996
<TABLE>
<CAPTION>
                                                          VALUE
         SHARES                                           (000)
- ---------------                                         ---------
<C>               <S>                                   <C>
COMMON STOCKS (86.5%)
  CAPITAL GOODS/CONSTRUCTION (7.2%)
    AEROSPACE & DEFENSE (4.7%)
         11,400    McDonnell Douglas Corp.              $   1,045
          8,100    United Technologies Corp.                  909
                                                        ---------
                                                            1,954
                                                        ---------
    BUILDING & CONSTRUCTION (1.5%)
         32,500    AMRE, Inc.                                 605
                                                        ---------
    MACHINERY (1.0%)
         10,600    Sundstrand Corp.                           432
                                                        ---------
  TOTAL CAPITAL GOODS/CONSTRUCTION                          2,991
                                                        ---------
  CONSUMER-CYCLICAL (17.2%)
    FOOD SERVICE & LODGING (13.7%)
         51,100    Boston Chicken, Inc.                     1,741
         45,800    HFS, Inc.                                2,227
          3,700    Hilton Hotels Corp.                        348
         10,200    ITT Corp. (New)                            612
         24,500    La Quinta Inns, Inc.                       720
                                                        ---------
                                                            5,648
                                                        ---------
    PUBLISHING (1.4%)
         49,100    K-III Communications Corp.                 571
                                                        ---------
    RETAIL-GENERAL (2.1%)
         11,200    AutoZone, Inc.                             379
         13,500    PetSmart, Inc.                             489
                                                        ---------
                                                              868
                                                        ---------
  TOTAL CONSUMER-CYCLICAL                                   7,087
                                                        ---------
  CONSUMER-STAPLES (30.6%)
    BEVERAGES (2.1%)
         28,100    Coca Cola Enterprises, Inc.                868
                                                        ---------
    DRUGS (2.2%)
         15,800    Schering-Plough Corp.                      918
                                                        ---------
    FOOD (2.8%)
         17,400    Ralston Purina Group                     1,164
                                                        ---------
    HEALTH CARE SUPPLIES & SERVICES (1.3%)
          3,200    Aetna Life & Casualty Co.                  242
          6,000    US Healthcare, Inc.                        275
                                                        ---------
                                                              517
                                                        ---------
    PERSONAL CARE PRODUCTS (0.9%)
          7,600    Tambrands, Inc.                            355
                                                        ---------
    TOBACCO (21.3%)
         84,800    Philip Morris Cos., Inc.                 7,441
         11,600    UST, Inc.                                  370
 
<CAPTION>
                                                          VALUE
         SHARES                                           (000)
- ---------------                                         ---------
<C>               <S>                                   <C>
         33,300    RJR Nabisco Holdings Corp.           $   1,007
                                                        ---------
                                                            8,818
                                                        ---------
  TOTAL CONSUMER-STAPLES                                   12,640
                                                        ---------
  DIVERSIFIED (6.2%)
         12,800    AlliedSignal, Inc.                         757
         24,100    Loews Corp.                              1,823
                                                        ---------
  TOTAL DIVERSIFIED                                         2,580
                                                        ---------
  FINANCE (24.3%)
    BANKING (15.7%)
          8,700    Chase Manhattan Corp.                      639
          6,600    First Interstate Bancorp                 1,145
         18,000    Wells Fargo & Co.                        4,698
                                                        ---------
                                                            6,482
                                                        ---------
    FINANCIAL SERVICES (4.0%)
          9,700    American Express Co.                       479
         10,400    CIGNA Corp.                              1,188
                                                        ---------
                                                            1,667
                                                        ---------
    INSURANCE (4.6%)
          8,800    Ace Ltd.                                   393
          8,200    CMAC Investment Corp.                      463
          7,000    Partnerre Holdings Ltd.                    208
         19,000    The PMI Group, Inc.                        829
                                                        ---------
                                                            1,893
                                                        ---------
  TOTAL FINANCE                                            10,042
                                                        ---------
  TECHNOLOGY (1.0%)
    COMPUTERS (1.0%)
          4,000    Microsoft Corp.                            413
                                                        ---------
TOTAL COMMON STOCKS (Cost $34,006)                         35,753
                                                        ---------
<CAPTION>
    NO. OF
   CONTRACTS
- ---------------
<C>               <S>                                   <C>
PURCHASED CALL OPTIONS (2.2%)
  CONSUMER-STAPLES (1.6%)
    TOBACCO (1.6%)
         13,700    Philip Morris Cos., Inc., expires
                    1/97, strike price $70                    267
         25,800    Philip Morris Cos., Inc., expires
                    1/98, strike price $80                    393
                                                        ---------
                                                              660
                                                        ---------
  FINANCE (0.6%)
    BANKING (0.6%)
          3,500    Wells Fargo & Co., expires 1/98,
                    strike price $200                         258
                                                        ---------
TOTAL PURCHASED CALL OPTIONS (Cost $860)                      918
                                                        ---------
</TABLE>
 
                                       3
<PAGE>
<TABLE>
<CAPTION>
     FACE
    AMOUNT                                                VALUE
     (000)                                                (000)
- ---------------                                         ---------
<C>               <S>                                   <C>
SHORT-TERM INVESTMENT (9.2%)
  REPURCHASE AGREEMENT (9.2%)
$         3,780    The Chase Manhattan Bank, N.A.,
                    5.15%, dated 3/29/96, due
                    4/01/96, to be repurchased at
                    $3,782, collateralized by $3,835
                    United States Treasury Notes,
                    6.00%, due 8/31/97, valued at
                    $3,859 (Cost $3,780)                $   3,780
                                                        ---------
TOTAL INVESTMENTS (97.9%) (Cost $38,646)                   40,451
                                                        ---------
OTHER ASSETS AND LIABILITIES (2.1%)
 Other Assets                                               2,012
 Liabilities                                               (1,153)
                                                        ---------
                                                              859
                                                        ---------
NET ASSETS (100%)                                       $  41,310
                                                        ---------
                                                        ---------
CLASS A SHARES:
 Net Assets                                               $37,482
 Shares Issued and Outstanding ($0.001 par value)
  (Authorized 500,000,000 shares)                           2,757
 Net Asset Value, Offering and Redemption Price
  Per Share                                                $13.60
                                                        ---------
                                                        ---------
CLASS B SHARES
 Net Assets                                                $3,828
 Shares Issued and Outstanding ($0.001 par value)
  (Authorized 500,000,000 shares)                             282
 Net Asset Value, Offering and Redemption Price
  Per Share                                                $13.59
                                                        ---------
                                                        ---------
 
</TABLE>
 
                                       4


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