MORGAN STANLEY INSTITUTIONAL FUND INC
497, 1997-12-10
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                       SUPPLEMENT DATED DECEMBER 10, 1997
                        TO PROSPECTUS DATED MAY 1, 1997
                 AS PREVIOUSLY SUPPLEMENTED SEPTEMBER 26, 1997
 
                      ACTIVE COUNTRY ALLOCATION PORTFOLIO
 
                                 A PORTFOLIO OF
 
              MORGAN STANLEY INSTITUTIONAL FUND, INC. (THE "FUND")
                                 P.O. BOX 2798
                             BOSTON, MASSACHUSETTS
                                   02208-2798
                                 -------------
 
    The  Prospectus is  being amended  and supplemented  to reflect  a change in
Portfolio Managers. Francine  Bovich and  Madhav Dhar  will no  longer serve  as
Portfolio  Managers. Accordingly,  the paragraph  under "PORTFOLIO  MANAGERS" on
page 16, is hereby deleted and replaced with the following:
 
    ANN D. THIVIERGE AND BARTON  M. BIGGS.  Ann D.  Thivierge is a Principal  of
the  Adviser.  She is  a  member of  the  Adviser's asset  allocation committee,
primarily representing the  Total Fund  Management team since  its inception  in
1991.  Prior to  joining the Adviser  in 1986,  she spent two  years at Edgewood
Management Company, a privately held  investment management firm. Ms.  Thivierge
holds  a B.A.  in International Relations  from James  Madison College, Michigan
State University, and an M.B.A. in  Finance from New York University. Barton  M.
Biggs  has been Chairman and a director of the Adviser since 1980 and a Managing
Director of Morgan Stanley  since 1975. He  is also a  director and chairman  of
various  registered investment companies to which the Adviser and certain of its
affiliates provide investment  advisory services.  Mr. Biggs holds  a B.A.  from
Yale  University and an M.B.A.  from New York University.  Ms. Thivierge and Mr.
Biggs have shared primary responsibility for managing the Portfolio since  June,
1995.
 
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               PLEASE RETAIN THIS SUPPLEMENT FOR FUTURE REFERENCE


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