MORGAN STANLEY INSTITUTIONAL FUND INC
N-30B-2, 1997-06-04
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<PAGE>
- ---------------------------------------------------
 
<TABLE>
<S>                                          <C>
DIRECTORS                                    OFFICERS
Barton M. Biggs                              James W. Grisham
CHAIRMAN OF THE BOARD                        VICE PRESIDENT
  Chairman and Director, Morgan Stanley      Michael F. Klein
Asset Management Inc. and Morgan Stanley     VICE PRESIDENT
Asset Management Limited; Managing           Harold J. Schaaff,
Director, Morgan Stanley & Co.               Jr.
Incorporated; Director, Morgan Stanley       VICE PRESIDENT
Group Inc.                                   Joseph P. Stadler
Warren J. Olsen                              VICE PRESIDENT
DIRECTOR AND PRESIDENT                       Valerie Y. Lewis
  Principal, Morgan Stanley Asset            SECRETARY
  Management Inc. and Morgan Stanley & Co.   Karl O. Hartmann
  Incorporated                               ASSISTANT SECRETARY
John D. Barrett II                           James R. Rooney
Chairman and Director,                       TREASURER
Barrett Associates, Inc.                     Joanna M. Haigney
Gerard E. Jones                              ASSISTANT TREASURER
Partner, Richards & O'Neil LLP
Andrew McNally IV
Chairman and Chief Executive Officer, Rand
McNally
Samuel T. Reeves
Chairman of the Board and CEO, Pinacle
L.L.C.
Fergus Reid
Chairman and Chief Executive Officer,
LumeLite Corporation
Frederick O. Robertshaw
Of Counsel, Bryan, Cave LLP
</TABLE>
 
- ------------------------------------------------------------------
INVESTMENT ADVISER AND ADMINISTRATOR
Morgan Stanley Asset Management Inc.
1221 Avenue of the Americas
New York, New York 10020
- ------------------------------------------------------------------
DISTRIBUTOR
Morgan Stanley & Co. Incorporated
1251 Avenue of the Americas
New York, New York 10020
- ---------------------------------------------------------
CUSTODIANS
The Chase Manhattan Bank
770 Broadway
New York, New York 10003
 
Morgan Stanley Trust Company
One Pierrepont Plaza
Brooklyn, New York 11210
- ------------------------------------------------------------------
LEGAL COUNSEL
Morgan, Lewis & Bockius LLP
2000 One Logan Square
Philadelphia, Pennsylvania 19103
- ------------------------------------------------------------------
INDEPENDENT ACCOUNTANTS
Price Waterhouse LLP
1177 Avenue of the Americas
New York, New York 10036
 
- ------------------------------------------------------------------
For  current performance, current  net asset value, or  for assistance with your
account, please contact the  Fund at (800) 548-7786.  This report is  authorized
for distribution only when preceded or accompanied by prospectuses of the Morgan
Stanley Institutional Fund, Inc.
 
[LOGO] MORGAN STANLEY
       INSTITUTIONAL FUND, INC.
       P.O. Box 2798
       Boston, MA 02208-2798
 
[LOGO] MORGAN STANLEY
       INSTITUTIONAL FUND, INC.
 
                         GLOBAL FIXED INCOME PORTFOLIO
                              FIRST QUARTER REPORT
                                 MARCH 31, 1997
<PAGE>
LETTER TO SHAREHOLDERS
- -------
 
The  Global Fixed Income  Portfolio aims to  produce an attractive  real rate of
return by  investing in  fixed  income securities  issued  by U.S.  and  foreign
issuers including governments, agencies, supranational entities and corporations
with varying maturities in various currencies.
 
For  the three months ended March 31, 1997,  the Portfolio had a total return of
- -3.72% for the Class A shares and -3.81% for the Class B shares as compared to a
total return  of  -3.90% for  the  J.P. Morgan  Traded  Global Bond  Index  (the
"Index"). The average annual total return for the one year and five-year periods
ended March 31, 1997
 
PERFORMANCE COMPARED TO THE J.P. MORGAN TRADED GLOBAL BOND INDEX(1)
- ----------------------------------------------------
 
<TABLE>
<CAPTION>
                                              TOTAL RETURNS(2)
                              ------------------------------------------------
                                                                     AVERAGE
                                                        AVERAGE      ANNUAL
                                             ONE        ANNUAL        SINCE
                                 YTD        YEAR      FIVE YEARS    INCEPTION
                              ---------  -----------  -----------  -----------
<S>                           <C>        <C>          <C>          <C>
PORTFOLIO--CLASS A..........      -3.72%       3.87%        6.97%        7.44%
PORTFOLIO--CLASS B(3).......      -3.81        3.74           NA         1.66
INDEX.......................      -3.90        2.16         8.01         8.69
</TABLE>
 
1.  The J.P. Morgan Traded Global Bond Index is an unmanaged Index of securities
    and  includes Australia,  Belgium, Canada, Denmark,  France, Germany, Italy,
    Japan, The Netherlands,  Spain, Sweden,  the United Kingdom  and the  United
    States.
 
2.  Total  returns for the Portfolio reflect  expenses waived and reimbursed, if
    applicable, by the  Adviser. Without  such waiver  and reimbursement,  total
    returns would be lower.
 
3.  The Portfolio began offering Class B shares on January 2, 1996.
 
PAST PERFORMANCE IS NOT PREDICTIVE OF FUTURE PERFORMANCE.
 
- ------------------------------
 
THE COUNTRY SPECIFIC PERFORMANCE RESULTS PROVIDED ARE FOR INFORMATIONAL PURPOSES
ONLY  AND  SHOULD NOT  BE CONSTRUED  AS  A GUARANTEE  OF THE  PORTFOLIO'S FUTURE
PERFORMANCE. PAST PERFORMANCE  SHOWN IS  NOT PREDICTIVE  OF FUTURE  PERFORMANCE.
INVESTMENT  RETURN  AND PRINCIPAL  VALUE WILL  FLUCTUATE  SO THAT  AN INVESTOR'S
SHARES, WHEN  REDEEMED, MAY  BE WORTH  MORE OR  LESS THAN  THEIR ORIGINAL  COST.
PLEASE  SEE  THE PROSPECTUS  FOR A  DESCRIPTION  OF CERTAIN  RISK CONSIDERATIONS
ASSOCIATED  WITH  INTERNATIONAL  INVESTING.  YIELDS  WILL  FLUCTUATE  AS  MARKET
CONDITIONS CHANGE.
 
and  for the  period from inception  on May 1,  1991 through March  31, 1997 was
3.87%, 6.97% and  7.44%, respectively,  for the Class  A shares  as compared  to
2.16%,  8.01% and 8.69%, respectively, for the  Index. As of March 31, 1997, the
Portfolio had an SEC 30-day yield of 5.10% for the Class A shares and 4.97%  for
the Class B shares.
 
Global  bond markets generated  poor returns during the  first quarter. Low bond
market returns in local currency terms  were compounded by a sharp  appreciation
of  the U.S. dollar. Fixed income returns  ranged from 2.2% in Japan to negative
1.5% in Italy  while currency  returns ranged  from -0.94%  against the  Swedish
krona to -0.8% against the Canadian dollar. It was a good quarter to be invested
in  bond  markets outside  the U.S.  but it  was not  profitable to  own foreign
currencies. Overall the global bond market returned -3.9% in U.S. dollar terms.
 
Following a  directionless  start  to  the  year,  U.S.  Treasuries  rallied  as
investors appeared to dismiss Greenspan's December warning of over-exuberance in
the equity market. However, the Fed Chairman's hawkish speech to Congress at his
Humphrey-Hawkins testimony in mid-February left little doubt about the direction
of  U.S. monetary policy. He emphasized the need for pre-emptive action to quell
incipient inflationary  pressures. Yields  rose  steadily, facilitating  a  calm
market  reaction to  the announcement of  a 25  basis point rise  in the Federal
funds rate in late March. The general view was that this was probably the  first
in  a  series of  tightenings  but that  much  less aggressive  action  would be
necessary than in 1994/95. Over the quarter 10-year yields rose 48 basis  points
and   U.S.  bonds  returned  -0.7%.   Canadian  bonds  outperformed  their  U.S.
counterparts  marginally,  returning  -0.4%   in  local  currency  terms   while
Australian  bonds  performed worse  than U.S.  bonds,  returning -0.75%  for the
quarter.
 
Japanese bonds continued to defy their  critics (their yields are the lowest  in
the  world  by far)  and surprise  investors with  their good  performance. They
returned
 
                                       2
<PAGE>
2.2% for the quarter,  a truly outstanding result  considering their yields  are
sub  2.5%. Mediocre economic performance, very low short term interest rates and
confidence that  the  central  bank  was  not  going  to  raise  rates  for  the
foreseeable  future propelled the market higher.  Concerns about the weakness of
the stock market  and possible  bank failures  further endorsed  the safe  haven
status of the bond market.
 
Core  European bond markets nicely outperformed U.S. Treasuries although returns
were not  high in  absolute terms.  For  example, Germany  returned 1%  for  the
quarter  which was better than Deutsche mark cash but underperformed U.S. dollar
cash. In  Germany,  increasing evidence  of  an economic  upturn  saw  investors
discard  any lingering expectations  of a final  Bundesbank easing. Despite this
stronger growth, there was increasing skepticism about Germany's ability to meet
the deficit criteria for monetary union. This brought the whole viability of the
monetary union timetable  into question and  divergence rather than  convergence
became the theme within the high yielding markets (Italy, Spain, Sweden returned
- -1.5%,  -0.1%,  and -0.6%,  respectively).  Domestic developments  in  Italy and
Sweden were  also  unfavorable. Italy's  long  awaited mini  budget  was  poorly
received  while in Sweden, there  was concern that policy  would shift to a less
restrictive stance. U.K. gilts performed in  line with core Europe, providing  a
safe  haven for investors from the uncertainties swirling around monetary union.
They were unfazed by the  announcement of a general  election for May where  the
long serving Conservative party is expected to be bounced from office.
 
The  dominant theme  in the  foreign exchange  market was  the sudden  and swift
appreciation of the U.S. dollar.  It appreciated against all currencies,  rising
by  7.6%  against the  Deutsche  mark and  6.3%  against the  Japanese  yen. The
principal reason behind the dollar's  ascent was the asymmetric monetary  policy
stances of central banks. While the Fed's tightening was justified by the strong
economic  data coming from the U.S. economy, the  same set of data in Europe and
Japan did not justify a commensurate reaction by their central banks. As long as
the data remains strong in the U.S. and the Fed continues to tighten, the dollar
is likely to remain strong.
 
J. David Germany
PORTFOLIO MANAGER
 
Michael B. Kushma
PORTFOLIO MANAGER
 
Paul F. O'Brien
PORTFOLIO MANAGER
 
Robert M. Smith
PORTFOLIO MANAGER
 
April 1997
 
                                       3
<PAGE>
INVESTMENTS (UNAUDITED)
- ----------
MARCH 31, 1997
<TABLE>
<CAPTION>
     FACE
    AMOUNT                                                                    VALUE
     (000)                                                                    (000)
- ---------------                                                             ---------
<C>               <S>                                                       <C>
 
FIXED INCOME SECURITIES (81.2%)
  AUSTRALIAN DOLLAR (1.8%)
    GOVERNMENT BOND (1.8%)
    AUD   2,400    Government of Australia 7.50%, 7/15/05                   $   1,833
                                                                            ---------
  BRITISH POUND (9.2%)
    EUROBOND (0.7%)
   GBP      370    Conversion 9.00%, 7/12/11                                      673
                                                                            ---------
    GOVERNMENT BONDS (8.5%)
          1,400    United Kingdom Treasury Gilt 7.00%, 11/06/01                 2,271
          2,300    United Kingdom Treasury Gilt 8.50%, 12/07/05                 3,990
          1,300    United Kingdom Treasury Gilt 8.50%, 7/16/07                  2,263
                                                                            ---------
                                                                                8,524
                                                                            ---------
                                                                                9,197
                                                                            ---------
  CANADIAN DOLLAR (3.1%)
    GOVERNMENT BONDS (3.1%)
   CAD    2,900    Government of Canada 7.50%, 3/01/01                          2,218
            950    Government of Canada 9.75%, 6/01/21                            877
                                                                            ---------
                                                                                3,095
                                                                            ---------
  DANISH KRONE (1.8%)
    GOVERNMENT BONDS (1.8%)
    DKK   6,100    Kingdom of Denmark 8.00%, 5/15/03                            1,056
          4,600    Kingdom of Denmark 8.00%, 3/15/06                              787
                                                                            ---------
                                                                                1,843
                                                                            ---------
  DEUTSCHE MARK (13.2%)
    EUROBOND (4.9%)
    DEM   7,700    Landeskreditbank Baden-Wuerttemberg Financial 6.625%,
                    8/20/03                                                     4,902
                                                                            ---------
    GOVERNMENT BONDS (8.3%)
          1,900    Deutschland Republic 7.125%, 12/20/02                        1,250
          5,850    German Unity Bond 8.00%, 1/21/02                             3,966
          2,000    Government of Germany 6.25%, 1/04/24                         1,139
          2,900    Treuhandanstalt 7.50%, 9/09/04                               1,941
                                                                            ---------
                                                                                8,296
                                                                            ---------
                                                                               13,198
                                                                            ---------
 
<CAPTION>
 
     FACE
    AMOUNT                                                                    VALUE
     (000)                                                                    (000)
- ---------------                                                             ---------
<C>               <S>                                                       <C>
  IRISH PUNT (2.0%)
    GOVERNMENT BOND (2.0%)
  IEP     1,250    Irish Government 6.25%, 4/01/99                          $   1,989
                                                                            ---------
  ITALIAN LIRA (4.9%)
    GOVERNMENT BONDS (4.9%)
  ITL 4,140,000    BTPS 10.50%, 7/15/00                                         2,684
        700,000    BTPS 10.00%, 8/01/03                                           462
      1,500,000    BTPS 9.50%, 1/01/05                                            972
      1,200,000    BTPS 9.50%, 2/01/06                                            784
                                                                            ---------
                                                                                4,902
                                                                            ---------
  JAPANESE YEN (8.8%)
    EUROBONDS (8.8%)
  JPY   120,000    European Investment Bank 6.625%, 3/15/00                     1,126
         60,000    Export Import Bank of Japan 4.375%, 10/01/03                   554
        290,000    International Bank for Reconstruction & Development
                    4.50%, 6/20/00                                              2,593
        130,000    International Bank for Reconstruction & Development
                    4.75%, 12/20/04                                             1,239
        200,000    Japan Development Bank 5.00%, 10/01/99                       1,776
        145,000    Republic of Austria 6.25%, 10/16/03                          1,476
                                                                            ---------
                                                                                8,764
                                                                            ---------
  SWEDISH KRONA (8.2%)
    GOVERNMENT BONDS (8.2%)
   SEK   19,300    Swedish Government 13.00%, 6/15/01                           3,217
         13,000    Swedish Government 10.25%, 5/05/03                           2,037
         23,500    Swedish Government 6.00%, 2/09/05                            2,938
                                                                            ---------
                                                                                8,192
                                                                            ---------
UNITED STATES DOLLAR (28.2%)
  CORPORATE BONDS AND NOTES (6.7%)
U.S.$       750    Asset Securitization Corp., CMO, 7.21%, 10/13/26               748
            981    Asset Securitization Corp., CMO, 7.10%, 8/13/29                971
            500    BankAmerica 7.70%, 12/31/26                                    464
            150    First Chicago, 7.75%, 12/01/26                                 139
            500    First Chicago, 7.95%, 12/01/26                                 477
            385    Goldman Sachs Group 6.25%, 2/01/03                             366
            869    LB Commercial Conduit Mortgage Trust (Floating Rate),
                    CMO, 7.14%, 8/25/04                                           849
</TABLE>
 
                                       4
<PAGE>
 
<TABLE>
<CAPTION>
     FACE
    AMOUNT                                                                    VALUE
     (000)                                                                    (000)
- ---------------                                                             ---------
<C>               <S>                                                       <C>
  CORPORATE BONDS AND NOTES (CONTINUED)
U.S.$       400    Liberty Mutual 7.875%, 10/15/26                          $     381
            300    Lumbermens Mutual Casualty Co., Series AI, 9.15%,
                    7/01/26                                                       318
          2,000    UCFC, CMO, Series 1995-C1, Class A3, 6.775%, 9/10/17         1,967
                                                                            ---------
                                                                                6,680
                                                                            ---------
  U.S. GOVERNMENT AND AGENCY OBLIGATIONS (20.2%)
    FEDERAL NATIONAL MORTGAGE ASSOCIATION (10.1%)
U.S.$       486    6.00%, 5/01/03                                                 465
          7,488    6.00%, 9/01/03                                               7,167
          2,649    6.50%, 1/01/26                                               2,461
                                                                            ---------
                                                                               10,093
                                                                            ---------
    U.S. TREASURY BOND (4.5%)
          4,165    8.125%, 8/15/19                                              4,567
                                                                            ---------
    U.S. TREASURY NOTES (5.6%)
          3,815    5.125%, 11/30/98                                             3,741
          1,800    7.25%, 5/15/04                                               1,835
                                                                            ---------
                                                                                5,576
                                                                            ---------
                                                                               20,236
                                                                            ---------
  YANKEE BONDS (1.3%)
U.S.$       765    Hydro-Quebec 7.50%, 4/01/16                                    740
            540    Industrial Finance Corp., 6.875%, 4/01/03                      520
                                                                            ---------
                                                                                1,260
                                                                            ---------
                                                                               28,176
                                                                            ---------
TOTAL FIXED INCOME SECURITIES (81.2%)
(Cost $84,433)                                                                 81,189
                                                                            ---------
 
     FACE
    AMOUNT                                                                    VALUE
     (000)                                                                    (000)
- ---------------                                                             ---------
SHORT-TERM INVESTMENTS (10.4%)
  JAPANESE YEN (3.3%)
    TIME DEPOSIT (3.3%)
  JPY   402,210    Japanese Time Deposit 0.36%, 4/01/97                     $   3,253
                                                                            ---------
  SPANISH PESETA (7.1%)
    TIME DEPOSIT (7.1%)
  ESP 1,007,768    Spanish Time Deposit 5.72%, 4/01/97                          7,133
                                                                            ---------
TOTAL SHORT-TERM INVESTMENTS (Cost $10,322)                                    10,386
                                                                            ---------
FOREIGN CURRENCY (0.0%)
   ESP    1,836    Spanish Peseta (Cost $13)                                       13
                                                                            ---------
TOTAL INVESTMENTS (91.6%) (Cost $94,768)                                       91,588
                                                                            ---------
OTHER ASSETS AND LIABILITIES (8.4%)
 Other Assets                                                                  53,820
 Liabilities                                                                  (45,423)
                                                                            ---------
                                                                                8,397
                                                                            ---------
NET ASSETS (100%)                                                           $  99,985
                                                                            ---------
                                                                            ---------
CLASS A:
NET ASSETS                                                                  $  99,332
NET ASSET VALUE, OFFERING AND REDEMPTION
  PRICE PER SHARE
  Applicable to 9,132,593 outstanding $0.001
  par value shares (authorized 500,000,000 shares)
                                                                               $10.88
                                                                            ---------
                                                                            ---------
CLASS B:
NET ASSETS                                                                       $653
NET ASSET VALUE, OFFERING AND REDEMPTION
  PRICE PER SHARE
  Applicable to 60,188 outstanding $0.001
  par value shares (authorized 500,000,000 shares)
                                                                               $10.86
                                                                            ---------
                                                                            ---------
</TABLE>
 
- ----------------------------------
CMO -- Collateralized Mortgage Obligation
 
                                       5


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