MORGAN STANLEY INSTITUTIONAL FUND INC
N-30B-2, 1997-06-04
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<PAGE>
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<TABLE>
<S>                                         <C>
DIRECTORS                                   OFFICERS
Barton M. Biggs                             James W. Grisham
CHAIRMAN OF THE BOARD                       VICE PRESIDENT
  Chairman and Director, Morgan Stanley     Michael F. Klein
  Asset Management Inc. and Morgan Stanley  VICE PRESIDENT
  Asset Management Limited; Managing        Harold J. Schaaff,
  Director, Morgan Stanley & Co.            Jr.
  Incorporated; Director, Morgan Stanley    VICE PRESIDENT
  Group Inc.                                Joseph P. Stadler
Warren J. Olsen                             VICE PRESIDENT
DIRECTOR AND PRESIDENT                      Valerie Y. Lewis
  Principal, Morgan Stanley Asset           SECRETARY
  Management Inc. and Morgan Stanley & Co.  Karl O. Hartmann
  Incorporated                              ASSISTANT SECRETARY
John D. Barrett II                          James R. Rooney
Chairman and Director,                      TREASURER
Barrett Associates, Inc.                    Joanna M. Haigney
Gerard E. Jones                             ASSISTANT TREASURER
Partner, Richards & O'Neil LLP
Andrew McNally IV
Chairman and Chief Executive Officer,
Rand McNally
Samuel T. Reeves
Chairman of the Board and CEO,
Pinacle L.L.C.
Fergus Reid
Chairman and Chief Executive Officer,
LumeLite Corporation
Frederick O. Robertshaw
Of Counsel, Bryan, Cave LLP
</TABLE>
 
- ------------------------------------------------------------------
INVESTMENT ADVISER AND ADMINISTRATOR
Morgan Stanley Asset Management Inc.
1221 Avenue of the Americas
New York, New York 10020
- ---------------------------------------------------------
DISTRIBUTOR
Morgan Stanley & Co. Incorporated
1251 Avenue of the Americas
New York, New York 10020
- ---------------------------------------------------------
CUSTODIANS
The Chase Manhattan Bank
770 Broadway
New York, New York 10003
 
Morgan Stanley Trust Company
One Pierrepont Plaza
Brooklyn, New York 11210
- ---------------------------------------------------------
LEGAL COUNSEL
Morgan, Lewis & Bockius LLP
2000 One Logan Square
Philadelphia, Pennsylvania 19103
- ---------------------------------------------------------
INDEPENDENT ACCOUNTANTS
Price Waterhouse LLP
1177 Avenue of the Americas
New York, New York 10036
 
- ---------------------------------------------------------
For  current performance, current  net asset value, or  for assistance with your
account, please contact the  Fund at (800) 548-7786.  This report is  authorized
for distribution only when preceded or accompanied by prospectuses of the Morgan
Stanley Institutional Fund, Inc.
 
[LOGO] MORGAN STANLEY
       INSTITUTIONAL FUND, INC.
       P.O. Box 2798
       Boston, MA 02208-2798
 
[LOGO] MORGAN STANLEY
       INSTITUTIONAL FUND, INC.
 
                        EMERGING MARKETS DEBT PORTFOLIO
                              FIRST QUARTER REPORT
                                 MARCH 31, 1997
<PAGE>
LETTER TO SHAREHOLDERS
- -------
 
The  investment objective of  the Emerging Markets Debt  Portfolio is high total
return  through  investment   primarily  in  debt   securities  of   government,
government-related and corporate issuers located in emerging countries.
 
For  the three months ended March 31, 1997,  the Portfolio had a total return of
4.51% for the Class A shares and 4.52%  for the Class B shares as compared to  a
total  return of 0.79% for the J.P. Morgan Emerging Markets Bond Plus Index. The
average annual total return for  the one year ended March  31, 1997 and for  the
period  from inception on February 1, 1994 through March 31, 1997 was 49.81% and
18.99%, respectively, for the Class A  shares as compared to 35.03% and  12.34%,
respectively,  for the Index. As  of March 31, 1997,  the Portfolio had a 30-day
yield of 8.78% for the Class A shares and 8.50% for the Class B shares.
 
PERFORMANCE COMPARED TO THE J.P. MORGAN EMERGING MARKETS BOND PLUS INDEX(1)
- ----------------------------------------------------
 
<TABLE>
<CAPTION>
                                          TOTAL RETURNS(2)
                              -----------------------------------------
                                             ONE       AVERAGE ANNUAL
                                 YTD        YEAR       SINCE INCEPTION
                              ---------  -----------  -----------------
<S>                           <C>        <C>          <C>
PORTFOLIO - CLASS A.........       4.51%      49.81%          18.99%
PORTFOLIO - CLASS B(3)......       4.52       49.37           42.40
INDEX.......................       0.79       35.03           12.34
</TABLE>
 
1.  The J.P. Morgan Emerging Markets Bond Plus Index is a market weighted  index
    composed  of Brady bonds, loans and Eurobonds,  as well as U.S. Dollar local
    market instruments of Argentina, Brazil, Bulgaria, Mexico, Morocco, Nigeria,
    the Philippines, Poland, Russia and South Africa.
 
2.  Total returns for the Portfolio  reflect expenses waived and reimbursed,  if
    applicable  by  the Adviser.  Without such  waiver and  reimbursement, total
    returns would be lower.
 
3.  The Portfolio began offering Class B shares on January 2, 1996.
 
PAST PERFORMANCE IS NOT PREDICTIVE OF FUTURE PERFORMANCE.
- ------------------------------
THE PERFORMANCE RESULTS PROVIDED ARE FOR INFORMATIONAL PURPOSES ONLY AND  SHOULD
NOT  BE CONSTRUED  AS A  GUARANTEE OF  THE PORTFOLIO'S  FUTURE PERFORMANCE. PAST
PERFORMANCE SHOWN IS NOT PREDICTIVE OF FUTURE PERFORMANCE. INVESTMENT RETURN AND
PRINCIPAL VALUE WILL FLUCTUATE SO THAT AN INVESTOR'S SHARES, WHEN REDEEMED,  MAY
BE  WORTH MORE OR LESS THAN THEIR ORIGINAL COST. PLEASE SEE THE PROSPECTUS FOR A
DESCRIPTION  OF  CERTAIN  RISK  CONSIDERATIONS  ASSOCIATED  WITH   INTERNATIONAL
INVESTING. YIELDS WILL FLUCTUATE AS MARKET CONDITIONS CHANGE.
 
For  the first few weeks of the year the trend of an across the board tightening
of credit  spreads  continued  unabated.  Attractive  relative  valuations,  the
stretch  for  incremental yield,  improving  sovereign credits  and  easy global
monetary conditions  prompted continued  increases  in allocations  to  emerging
market  assets. Chairman  Greenspan's comments on  the state  of credit markets,
extended valuations  and  mispricing of  risks  stopped the  music  suddenly.  A
correction  in fixed  income markets  started in the  last week  of February and
lasted for practically all of the month of March.
 
It is  always easier  with hindsight  to  point out  the excesses  in  financial
markets,  but the only common theme this time around was the fact that it was no
different than the  last time  we encountered clear-air  turbulence in  emerging
markets.  Valuations  always  look  stretched  but  somehow  always justifiable,
late-comers  to  the  party  are  the  first  to  get  "excessively  exuberant",
self-fulfilling  circular loops  of logic are  in fashion,  hot investment ideas
proliferate as  bull market  geniuses  are spawned  every day  and  unsuspecting
investment  professionals dance to the "its  different this time around" chorus.
Before anyone knows it, a  bear market/serious correction suddenly appears  from
out  of  the  blue.  The  specific catalyst  or  trigger  can  somehow  never be
anticipated, as corrections seldom arrive accompanied by the sound of drums  and
music.  Two things  remain true  no matter  what: that  bulls are  mortal and it
always appears  pitch black  before the  dawn of  a rally.  So when  the Fed  is
expected to move another 100 basis points in 1997, political cycles are expected
to  wreck the improving economic stories, oil  prices are headed to $10 a barrel
and some emerging country is close to a default, it will be time to buy emerging
market bonds again. Or will it?
 
The markets  didn't  surprise  by  behaving differently  this  time  around.  An
increase  in risk premiums  affected all countries and  all bonds. A correction,
precipitated by possible Fed action and deepened by redemptions and a  reduction
in  committed capital, tends to affect the broad market. Hot investments tend to
get hit  the hardest  as positions  need to  be reduced  and the  demand  supply
 
                                       2
<PAGE>
imbalance  grows exponentially. The weight of money heading for the exits drowns
the  fundamentals  for  a  while.  The  overbought  and  the  overowned   assets
underperformed  as expected.  The only safe  havens proved  to be short-duration
floating rate bonds  of Argentina,  Brazil and  Morocco. The  resilience of  the
Mexican  peso surprised everyone and assets with low correlations with the broad
market performed reasonably.
 
Over the  course  of  the  quarter though,  the  improving  credit  stories  did
outperform.  Argentina, Brazil, Bulgaria, Mexico and  Morocco did manage to hold
on  to   positive   returns.   The   countries   with   deteriorating   outlooks
underperformed.   Ecuador,  Venezuela  and  Russia  took  up  the  rear  of  the
performance pack. The performance of Panama, Peru, Philippines and Poland proved
to be nothing to write home about.
 
The Portfolio outperformed by sticking to our convictions. Buying cheap  credits
with  an improving economic outlook proved successful in Bulgaria as we retained
our overweight  in the  best performing  country for  the quarter  based on  the
premise  that a political  consensus existed to  undertake serious macroeconomic
stabilization for the  first time in  many years. A  transition government  that
replaced  the ex-socialists negotiated for  help from the International Monetary
Fund, the World Bank  and the European Union  for external financing that  would
improve  the country's ability to implement a currency board after the elections
scheduled for mid-April. The reformers are expected to win and implement the IMF
prescribed stabilization and de-regulation program.
 
Our focus on values and improvement steered us away from the pitfalls in Ecuador
as an ambitious President was ousted by the population on charges of corruption,
nepotism and conservatism. Economic policies, however well crafted, need careful
execution. Ecuador  reminded  us that  drastic  reform can  run  the risk  of  a
backlash.  We  managed to  side-step the  problems by  reducing our  exposure as
valuations became stretched and the first sign of trouble emerged.
 
Mexico proved to be a difficult country  in 1997. The strong tail-winds of  firm
oil prices, low global interest rates and a weak peso turned into head winds for
the  first time since the  crisis of 1995. Expensive  assets and risk of further
political upheaval before  the elections in  July did not  warrant an  excessive
allocation.  The country performed well in  January as excessive liquidity drove
spreads lower but has underperformed the market since.
 
Argentina, on the  other hand,  was an  easier credit  to invest  in. A  buoyant
economy,  bouncing of cyclical troughs, improved domestic sentiment. Intelligent
pre-financing of the government borrowing needs during easy money conditions and
refocus on structural  reform of the  labor markets reduced  perceived risks.  A
manageable  fiscal  position and  ample domestic  liquidity helped  Argentina to
remain as one of the top performers in 1997.
 
The Portfolio invested  in rand  denominated South  African gilts  as high  real
interest rates and a cheap currency proved to be attractive. Interest rates were
maintained  at high  levels as  the Central  Bank sought  to cool  the growth in
private sector credit. The  prospect of declining inflation  over the course  of
the  year and a tight  fiscal policy made the  local bond market attractive. The
currency should find support from a much smaller trade balance and privatization
related inflows during 1997.
 
We reduced positions in  Morocco as the economic  recovery after the drought  in
1995  was  fully priced  into current  prices  and implementation  of structural
reforms seemed to be losing steam during 1997. The prospect of favorable ratings
also buoyed prices. We used  the rally in prices  during February to reduce  our
allocations  to Morocco. We will consider  increasing them again once valuations
reach attractive levels  and are consistent  with an expected  rating in the  BB
category.
 
Brazil  weathered its  first concern over  the currency fairly  well, but doubts
over the sustainability of  the current regime remain.  The appearance of  large
trade  deficits cast doubts on the  governments balance of policies. Clearly, in
the absence of  a reduction in  the growth of  domestic demand, higher  interest
rates  or a tighter fiscal policy  are inevitable. Privatizations and amendments
to the  constitution may  provide  short-term relief.  The government  needs  to
deliver  on key reform initiatives this year to safeguard the long-run viability
of the Real plan.
 
                                       3
<PAGE>
We reduced  our  allocations to  Brazil  as  relative valuations  proved  to  be
unattractive compared to the possible downside risks in the absence of reform.
 
A  decline in oil prices burst  Venezuela's bubble. Venezuela has benefited from
the rally in oil prices as higher oil prices have increased foreign reserves  of
the  Central Bank as well  as improved the fiscal  position of the government. A
slight delay in enacting other reform  measures such as the labor and  severance
pay  reform bill and the  granting of high adjustments  to salaried workers gave
investors the  excuse  to  take  profits. Price  declines  were  severe  as  the
Venezuelan  story  had been  bought by  all.  We did  not materially  change our
exposure to Venezuela during the quarter.
 
The outlook for the market is dependent on the course of U.S. interest rates. At
this time it appears that another 50 basis points increase in Fed funds will  be
necessary  to slow demand. Higher  wages and a resultant  increase in unit labor
costs threatens the period of  price stability that we  have had since the  late
1980's.  Once this has been priced into the  bond market and a certain amount of
stability returns to the U.S. bond market, emerging market bonds should recover.
The correction  in prices  has  restored valuations  to attractive  levels.  Any
further declines in the absence of any major increase in U.S. rates should prove
to  be buying opportunities. A buoyant U.S. dollar, a competitive environment in
goods and labor markets  in the U.S.,  a general lack of  pricing power and  the
absence  of a  synchronized expansion  in Europe and  some parts  of Asia should
limit the dangers of inflation in the near term.
 
Paul Ghaffari
PORTFOLIO MANAGER
 
April 1997
 
                                       4
<PAGE>
INVESTMENTS (UNAUDITED)
- ----------
MARCH 31, 1997
<TABLE>
<CAPTION>
     FACE
    AMOUNT                                                VALUE
     (000)                                                (000)
- ---------------                                         ---------
<C>               <S>                                   <C>
DEBT INSTRUMENTS (104.0%)
  ARGENTINA (22.0%)
    BONDS (22.0%)
$         2,200    Republic of Argentina BOCON,
                    Series D-1, 4/01/07                 $   2,539
          3,300    Republic of Argentina Par Bonds,
                    Series L, (Step Bond), 5.00%,
                    3/31/23                                 2,065
      ARP 4,700    Republic of Argentina, Series
                    144A, 11.75%, 2/12/07                   4,727
$        27,257    Republic of Argentina, Series L,
                    "Euro", (Floating Rate) 6.75%,
                    3/31/05                                24,395
            625    Republic of Argentina Global Bond,
                    11.375%, 1/30/17                          644
                                                        ---------
                                                           34,370
                                                        ---------
  BRAZIL (13.5%)
    BONDS (13.5%)
$           900    Federated Republic of Brazil
                    Discount Bond, Series Z-L,
                    (Floating Rate), 6.875%, 4/15/24          723
          7,500    Brazil Credit Linked Enhanced Note
                    9.00%, 1/05/99                          7,715
          8,750    Federative Republic of Brazil Debt
                    Conversion Bond, Series Z-L,
                    (Floating Rate) 6.563%, 4/15/12         6,904
          7,820    Federative Republic of Brazil, C
                    Bond, PIK, 8.00%, 4/15/04               5,823
                                                        ---------
                                                           21,165
                                                        ---------
  BULGARIA (9.4%)
    BONDS (9.4%)
$         2,600    Bulgaria Discount Bond, Series A,
                    "Euro", (Floating Rate) 6.563%,
                    7/28/24                                 1,544
         21,450    Bulgaria Front Loaded Interest
                    Reduction Bond, Series A, 2.25%,
                    7/28/12                                 9,036
          7,100    Bulgaria Interest Arrears PDI
                    Bond, (Floating Rate) 6.563%,
                    7/28/11                                 4,060
                                                        ---------
                                                           14,640
                                                        ---------
  ECUADOR (4.7%)
    BONDS (4.7%)
$         3,300    Ecuador Discount Bond, (Floating
                    Rate) 6.438%, 2/28/25                   2,141
          8,261    Republic of Ecuador PDI Bond,
                    (Floating Rate), 6.438%, 2/27/15        4,703
 
<CAPTION>
 
     FACE
    AMOUNT                                                VALUE
     (000)                                                (000)
- ---------------                                         ---------
<C>               <S>                                   <C>
$         1,200    Republic of Ecuador Par Bond,
                    (Step Bond), 3.25%, 2/28/25         $     495
                                                        ---------
                                                            7,339
                                                        ---------
  IVORY COAST (3.5%)
    LOAN AGREEMENTS (3.5%)
      DEM 2,295    Ivory Coast Loan Agreement                 538
     FRF 59,100    Ivory Coast Loan Agreement               4,250
$         1,800    Ivory Coast Loan Agreement                 689
                                                        ---------
                                                            5,477
                                                        ---------
  JAMAICA (2.7%)
    BOND(2.7%)
          4,000    Mechala Group, Jamaica, 12.75%,
                    12/30/99                                4,140
                                                        ---------
  MEXICO (9.8%)
    BONDS (6.4%)
$         4,500    Empresas ICA Sociedad, Series
                    Regs, 11.875%, 5/30/01                  4,793
      ZAR 8,000    Nacional Financiera SNC, 17.00%,
                    2/26/99                                 1,783
$         3,250    United Mexican States Global Bond,
                    11.50%, 5/15/26                         3,364
                                                        ---------
                                                            9,940
                                                        ---------
    NOTE (3.4%)
          8,000    United Mexican States Stripped
                    Note, 6.375%, 9/09/97                   5,377
                                                        ---------
                                                           15,317
                                                        ---------
  PANAMA (1.3%)
    BONDS (1.3%)
            140    Republic of Panama Interest
                    Reduction Bond, "Euro", (Floating
                    Rate), 3.50%, 7/17/14                      98
          1,962    Republic of Panama Interest
                    Reduction Bond, (Floating Rate),
                    3.50%, 7/17/14                          1,368
            710    Republic of Panama PDI Bond,
                    (Floating Rate), 6.563%, 7/17/16          566
                                                        ---------
                                                            2,032
                                                        ---------
  PERU (4.3%)
    BONDS (4.3%)
          7,198    Republic of Peru Front Loaded
                    Interest Reduction Bond, Series
                    US, (Step Bond), 3.25%, 3/07/17         3,725
</TABLE>
 
                                       5
<PAGE>
<TABLE>
<CAPTION>
     FACE
    AMOUNT                                                VALUE
     (000)                                                (000)
- ---------------                                         ---------
<C>               <S>                                   <C>
$         5,235    Republic of Peru, (Step Bond),
                    4.00%, 3/07/17                      $   3,010
                                                        ---------
                                                            6,735
                                                        ---------
  RUSSIA (21.7%)
    BONDS (12.1%)
         18,437    Ministry of Finance Tranche IV,
                    GDR, 3.00%, 5/14/03                    11,316
          4,500    Ministry of Finance Tranche IV,
                    "Euro", GDR, 3.00%, 5/14/03             2,762
         10,100    Ministry of Finance Series VI,
                    GDR, 3.00%, 5/14/06                     4,892
                                                        ---------
                                                           18,970
                                                        ---------
    LOAN AGREEMENT (3.6%)
          7,150    Bank for Foreign Economic Affairs,
                    (Floating Rate) 12/31/99
                    (Participation: J.P. Morgan,
                    Chase, and Salomon Brothers)            5,595
                                                        ---------
    NOTES (6.0%)
          2,800    Russian Interest Arrears Note,
                    12/31/99                                1,894
         13,300    Russia Principal Notes, 12/31/99         7,481
                                                        ---------
                                                            9,375
                                                        ---------
                                                           33,940
                                                        ---------
  SOUTH AFRICA (2.3%)
    BONDS (2.3%)
     ZAR 18,200    Republic of South Africa, Series
                    150, 12.00%, 2/28/05                    3,535
                                                        ---------
  VENEZUELA (8.8%)
    BONDS (8.8%)
$           238    Republic of Venezuela Front Loaded
                    Interest Reduction Bonds, Series
                    A, (Floating Rate) 6.75%, 3/31/07         208
          8,810    Republic of Venezuela Front Loaded
                    Interest Reduction Bonds, Series
                    B, (Floating Rate), 6.75%,
                    3/31/07                                 7,683
          5,200    Republic of Venezula Discount
                    Bonds, Series A, (Floating Rate),
                    6.438%, 3/31/20                         4,225
          2,100    Republic of Venezuela Discount
                    Bonds, Series B, (Floating Rate),
                    6.375%, 3/31/20                         1,706
                                                        ---------
                                                           13,822
                                                        ---------
TOTAL DEBT INSTRUMENTS (Cost $166,640)                    162,512
                                                        ---------
 
<CAPTION>
 
     FACE
    AMOUNT                                                VALUE
     (000)                                                (000)
- ---------------                                         ---------
<C>               <S>                                   <C>
SHORT-TERM INVESTMENT (4.9%)
  REPURCHASE AGREEMENT (4.9%)
U.S.$     7,691    Chase Securities, Inc. 6.00%,
                    dated 3/31/97, due 4/01/97, to be
                    repurchased at $7,692,
                    collateralized by U.S. Treasury
                    Bonds, 11.25%, due 2/15/15,
                    valued at $7,849 (Cost $7,691)      $   7,691
                                                        ---------
TOTAL INVESTMENTS (108.9%) (Cost $174,331)                170,203
                                                        ---------
OTHER ASSETS AND LIABILITIES (-8.9%)
 Other Assets                                              42,717
 Liabilities                                              (56,601)
                                                        ---------
                                                          (13,884)
                                                        ---------
NET ASSETS (100%)                                       $ 156,319
                                                        ---------
                                                        ---------
CLASS A:
NET ASSETS                                               $153,678
NET ASSET VALUE, OFFERING AND REDEMPTION
  PRICE PER SHARE
  Applicable to 19,507,045 outstanding $0.001 par
  value shares (authorized 500,000,000 shares)              $7.88
                                                        ---------
                                                        ---------
CLASS B:
NET ASSETS                                                 $2,641
NET ASSET VALUE, OFFERING AND REDEMPTION
  PRICE PER SHARE
  Applicable to 335,543 outstanding $0.001 par value
  shares (authorized 500,000,000 shares)                    $7.87
                                                        ---------
                                                        ---------
</TABLE>
 
- ------------------------------
GDR -- GLOBAL DEPOSITARY RECEIPT.
PDI -- PAST DUE INTEREST.
PIK -- PAYMENT-IN-KIND. INCOME MAY BE PAID IN ADDITIONAL SECURITIES OR CASH AT
       THE DISCRETION OF THE ISSUER.
FLOATING RATE -- INTEREST RATE CHANGES ON THESE INSTRUMENTS ARE BASED ON CHANGES
IN A DESIGNATED BASE RATE. THE RATES SHOWN ARE THOSE IN EFFECT AT MARCH 31,
1997.
STEP BOND -- COUPON RATE INCREASES IN INCREMENTS TO MATURITY. RATE DISCLOSED IS
AS OF MARCH 31, 1997. MATURITY DATE DISCLOSED IS THE ULTIMATE MATURITY.
 
                                       6


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