MORGAN STANLEY INSTITUTIONAL FUND INC
485BPOS, 1997-05-01
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<PAGE>

   
    
                                                               File No. 33-23166
                                                                        811-5624
- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------


                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                                 --------------
                                    FORM N-1A
                      REGISTRATION STATEMENT (NO. 33-23166)
                                      UNDER

   
                           THE SECURITIES ACT OF 1933
                         Post-Effective Amendment No. 34
                                       and
                        REGISTRATION STATEMENT UNDER THE
                         INVESTMENT COMPANY ACT OF 1940
                                Amendment No. 35
    

                                 --------------

                     MORGAN STANLEY INSTITUTIONAL FUND, INC.
               (Exact Name of Registrant as Specified in Charter)
             1221 Avenue of the Americas, New York, New York  10020
                     (Address of Principal Executive Office)
                  Registrant's Telephone Number (800) 548-7786

                         Harold J. Schaaff, Jr., Esquire
                      Morgan Stanley Asset Management Inc.
             1221 Avenue of the Americas, New York, New York  10020
                     (Name and Address of Agent for Service)

                                 --------------

                                   COPIES TO:
             Warren J. Olsen                        Richard W. Grant, Esquire
Morgan Stanley Asset Management Inc.            Morgan, Lewis & Bockius LLP
       1221 Avenue of the Americas                  2000 One Logan Square
          New York, NY 10020                          Philadelphia, PA 19103

                                 --------------


          IT IS PROPOSED THAT THIS FILING WILL BECOME EFFECTIVE
              (CHECK APPROPRIATE BOX)
   
          / /  IMMEDIATELY UPON FILING PURSUANT TO PARAGRAPH (b) OF RULE 485
          /X/  ON MAY 1, 1997 PURSUANT TO PARAGRAPH (b) OF RULE 485
          / /  60 DAYS AFTER FILING PURSUANT TO PARAGRAPH (a) OF RULE 485
          / /  75 DAYS AFTER FILING PURSUANT TO PARAGRAPH (a) OF RULE 485
          / /  ON _______________ PURSUANT TO PARAGRAPH (a) OF RULE 485
    
                               ------------------

   
     Registrant has elected to register an indefinite number of shares pursuant
to Rule 24f-2 under the Investment Company Act of 1940, as amended.  Registrant
filed its Rule 24f-2 notice for the period ended December 31, 1996 on February
21, 1997.
    
- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------

<PAGE>


                     MORGAN STANLEY INSTITUTIONAL FUND, INC.
                              CROSS REFERENCE SHEET

PART A -INFORMATION REQUIRED IN A PROSPECTUS
   
 Form N-1A
Item Number  Location in Prospectus for the Fixed Income, Municipal Bond, 
- -----------  Mortgage-Backed  Securities, Money Market and Municipal Money 
             Market Portfolios
             -------------------------------------------------------------------
    
Item 1.   Cover Page -- Cover Page

Item 2.   Synopsis-- Fund Expenses (Estimated for Mortgage-Backed Securities
          Portfolio)

Item 3.   Condensed Financial Information -- Financial Highlights (for the Fixed
          Income, Global Fixed Income, Municipal Bond, High Yield, Money Market
          and Municipal Money Market Portfolios only); Performance Information

Item 4.   General Description of Registrant -- Prospectus Summary; Investment
          Objective and Policies; Additional Investment Information; Investment
          Limitations; General Information

Item 5.   Management of the Fund -- Prospectus Summary; Management of the Fund;
          Portfolio Transactions

Item 5A.  Management's Discussion of Fund Performance**

Item 6.   Capital Stock and Other Securities -- Purchase of Shares; Redemption
          of Shares; Shareholder Services; Valuation of Shares; Dividends and
          Capital Gains Distributions; Taxes; General Information

Item 7.   Purchase of Securities Being Offered -- Prospectus Summary; Cover
          Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.   Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
          Shareholder Services

Item 9.   Pending Legal Proceedings -- *
   
 Form N-1A
Item Number  Location in Prospectus for the Small Cap Value Equity, Value
- -----------  Equity, Balanced, Global Fixed Income and High Yield Portfolios
             -------------------------------------------------------------------
    
Item 1.   Cover Page -- Cover Page

Item 2.   Synopsis -- Fund Expenses

Item 3.   Condensed Financial Information -- Financial Highlights; Performance
          Information

Item 4.   General Description of Registrant -- Prospectus Summary; Investment
          Objective and Policies; Additional Investment Information; Investment
          Limitations; General Information

Item 5.   Management of the Fund -- Prospectus Summary; Management of the Fund;
          Portfolio Transactions




Item 5A.  Management's Discussion of Fund Performance**

Item 6.   Capital Stock and Other Securities -- Purchase of Shares; Redemption
          of Shares; Shareholder Services; Valuation of Shares; Dividends and
          Capital Gains Distributions; Taxes; General Information

Item 7.   Purchase of Securities Being Offered -- Prospectus Summary; Cover
          Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.   Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
          Shareholder Services

Item 9.   Pending Legal Proceedings -- *
_______________________
*      Omitted since the answer is negative or the Item is not applicable. 
   
**     Information required by Item 5A is contained in the 1996 Annual Report
       to Shareholders, except for the following portfolios which were not in
       operation at December 31, 1996:  Mortgage-Backed Securities, China
       Growth and MicroCap Portfolios. Information required by Item 5A for the 
       aforementioned portfolios will be contained in the next
       Report to Shareholders following commencement of operations.
    
<PAGE>

 Form N-1A
Item Number    Location in Prospectus for the Active Country Allocation
- -----------    Portfolio
               ---------------------------------------------------------

Item 1.   Cover Page -- Cover Page

Item 2.   Synopsis -- Fund Expenses 

Item 3.   Condensed Financial Information -- Financial Highlights; Performance
          Information

Item 4.   General Description of Registrant -- Prospectus Summary; Investment
          Objective and Policies; Additional Investment Information; Investment
          Limitations; General Information

Item 5.   Management of the Fund -- Prospectus Summary; Management of the Fund;
          Portfolio Transactions

Item 5A.  Management's Discussion of Fund Performance**

Item 6.   Capital Stock and Other Securities -- Purchase of Shares; Redemption
          of Shares; Shareholder Services; Valuation of Shares; Dividends and
          Capital Gains Distributions; Taxes; General Information

Item 7.   Purchase of Securities Being Offered -- Prospectus Summary; Cover
          Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.   Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
          Shareholder Services

Item 9.   Pending Legal Proceedings -- *

 Form N-1A
Item Number         Location in Prospectus for Gold Portfolio
- -----------         -----------------------------------------

Item 1.   Cover Page -- Cover Page

Item 2.   Synopsis -- Fund Expenses

Item 3.   Condensed Financial Information -- Financial Highlights; Performance
          Information

Item 4.   General Description of Registrant -- Prospectus Summary; Investment
          Objective and Policies; Additional Investment Information; Investment
          Limitations; General Information

Item 5.   Management of the Fund -- Prospectus Summary; Management of the Fund;
          Portfolio Transactions

Item 5A.  Management's Discussion of Fund Performance**

Item 6.   Capital Stock and Other Securities -- Purchase of Shares; Redemption
          of Shares; Shareholder Services; Valuation of Shares; Dividends and
          Capital Gains Distributions; Taxes; General Information

Item 7.   Purchase of Securities Being Offered -- Prospectus Summary; Cover
          Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.   Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
          Shareholder Services

Item 9.   Pending Legal Proceedings -- *


_______________________
*      Omitted since the answer is negative or the Item is not applicable. 
   
**     Information required by Item 5A is contained in the  1996 Annual Report
       to Shareholders, except for the following portfolios which were not in
       operation at December 31, 1996:  Mortgage-Backed Securities, China
       Growth and MicroCap Portfolios. Information required by Item 5A for the 
       aforementioned portfolios will be contained in the next Report to 
       Shareholders  following commencement of operations.
    
<PAGE>

Form N-1A    Location in Prospectus for the Global Equity, International Equity,
Item Number  International Small Cap, Asian Equity, European Equity, Japanese
- -----------  Equity and Latin American Portfolios                
             -------------------------------------------------------------------

Item 1.   Cover Page -- Cover Page

Item 2.   Synopsis -- Fund Expenses 

Item 3.   Condensed Financial Information -- Financial Highlights; Performance
          Information



Item 4.   General Description of Registrant -- Prospectus Summary; Investment
          Objective and Policies; Additional Investment Information; Investment
          Limitations; General Information

Item 5.   Management of the Fund -- Prospectus Summary; Management of the Fund;
          Portfolio Transactions

Item 5A.  Management's Discussion of Fund Performance**

Item 6.   Capital Stock and Other Securities -- Purchase of Shares; Redemption
          of Shares; Shareholder Services; Valuation of Shares; Dividends and
          Capital Gains Distributions; Taxes; General Information

Item 7.   Purchase of Securities Being Offered -- Prospectus Summary; Cover
          Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.   Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
          Shareholder Services

Item 9.   Pending Legal Proceedings -- *

Form N-1A
Item Number    Location in Prospectus for the Emerging Markets and Emerging
- ----------     Markets Debt Portfolios
               ------------------------------------------------------------

Item 1.   Cover Page -- Cover Page

Item 2.   Synopsis -- Fund Expenses 

Item 3.   Condensed Financial Information -- Financial Highlights; Performance
          Information

Item 4.   General Description of Registrant -- Prospectus Summary; Investment
          Objective and Policies; Additional Investment Information; Investment
          Limitations; General Information

Item 5.   Management of the Fund -- Prospectus Summary; Management of the Fund;
          Portfolio Transactions

Item 5A.  Management's Discussion of Fund Performance**

Item 6.   Capital Stock and Other Securities -- Purchase of Shares; Redemption
          of Shares; Shareholder Services; Valuation of Shares; Dividends and
          Capital Gains Distributions; Taxes; General Information

Item 7.   Purchase of Securities Being Offered -- Prospectus Summary; Cover
          Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.   Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
          Shareholder Services

Item 9.   Pending Legal Proceedings -- *

_______________________
*      Omitted since the answer is negative or the Item is not applicable. 
   
**     Information required by Item 5A is contained in the  1996 Annual Report
       to Shareholders, except for the following portfolios which were not in
       operation at December 31, 1996:  Mortgage-Backed Securities, China
       Growth and MicroCap Portfolios. Information required by Item 5A for the 
       aforementioned portfolios will be contained in the next Report to 
       Shareholders following commencement of operations.
    
<PAGE>

 Form N-1A
Item Number   Location in Prospectus for the China Growth Portfolio
- -----------   -----------------------------------------------------

Item 1.   Cover Page -- Cover Page

Item 2.   Synopsis -- Fund Expenses (Estimated)

Item 3.   Condensed Financial Information -- Financial Highlights; Performance
          Information

Item 4.   General Description of Registrant -- Prospectus Summary; Investment
          Objective and Policies; Additional Investment Information; Investment
          Limitations; General Information

Item 5.   Management of the Fund -- Prospectus Summary; Management of the Fund;
          Portfolio Transactions

Item 5A.  Management's Discussion of Fund Performance**

Item 6.   Capital Stock and Other Securities -- Purchase of Shares; Redemption
          of Shares; Shareholder Services; Valuation of Shares; Dividends and
          Capital Gains Distributions; Taxes; General Information

Item 7.   Purchase of Securities Being Offered -- Prospectus Summary; Cover
          Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.   Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
          Shareholder Services

Item 9.   Pending Legal Proceedings -- *

 Form N-1A
Item Number    Location in Prospectus for the Equity Growth, Emerging Growth,
- -----------    Microcap and Aggressive Equity Portfolios
               --------------------------------------------------------------

Item 1.   Cover Page -- Cover Page
     
Item 2.   Synopsis -- Fund Expenses (Estimated for the MicroCap Portfolio)

Item 3.   Condensed Financial Information -- Financial Highlights (for the
          Equity Growth, Emerging Growth and Aggressive Equity Portfolios only);
          Performance Information

Item 4.   General Description of Registrant -- Prospectus Summary; Investment
          Objective and Policies; Additional Investment Information; Investment
          Limitations; General Information

Item 5.   Management of the Fund -- Prospectus Summary; Management of the Fund;
          Portfolio Transactions

Item 5A.  Management's Discussion of Fund Performance**

Item 6.   Capital Stock and Other Securities -- Purchase of Shares; Redemption
          of Shares; Shareholder Services; Valuation of Shares; Dividends and
          Capital Gains Distributions; Taxes; General Information

Item 7.   Purchase of Securities Being Offered -- Prospectus Summary; Cover
          Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.   Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
          Shareholder Services

Item 9.   Pending Legal Proceedings -- *

_______________________
*      Omitted since the answer is negative or the Item is not applicable. 
   
**     Information required by Item 5A is contained in the  1996 Annual Report
       to Shareholders, except for the following portfolios which were not in
       operation at December 31, 1996:  Mortgage-Backed Securities, China
       Growth and MicroCap Portfolios. Information required by Item 5A for the 
       aforementioned portfolios will be contained in the next Report to
       Shareholders following commencement of operations.
    
<PAGE>


Form N-1A
Item number Location in Prospectus for the U.S. Real Estate Portfolio
- ----------- ---------------------------------------------------------

Item 1.   Cover Page -- Cover Page

Item 2.   Synopsis -- Fund Expenses 

Item 3.   Condensed Financial Information -- Financial Highlights; Performance
          Information

Item 4.   General Description of Registrant -- Prospectus Summary; Investment
          Objective and Policies; Additional Investment Information; Investment
          Limitations; General Information

Item 5.   Management of the Fund -- Prospectus Summary; Management of the Fund;
          Portfolio Transactions

Item 5A.  Management's Discussion of Fund Performance**

Item 6.   Capital Stock and Other Securities -- Purchase of Shares; Redemption
          of Shares; Shareholder Services; Valuation of Shares; Dividends and
          Capital Gains Distributions; Taxes; General Information

Item 7.   Purchase of Securities Being Offered -- Prospectus Summary; Cover
          Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.   Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
          Shareholder Services

Item 9.   Pending Legal Proceedings -- *

 Form N-1A
Item Number    Location in Prospectus for the International Magnum Portfolio
- -----------    -------------------------------------------------------------


Item 1.   Cover Page -- Cover Page

Item 2.   Synopsis -- Fund Expenses (Estimated)

Item 3.   Condensed Financial Information -- Financial Highlights; Performance
          Information

Item 4.   General Description of Registrant -- Prospectus Summary; Investment
          Objective and Policies; Additional Investment Information; Investment
          Limitations; General Information

Item 5.   Management of the Fund -- Prospectus Summary; Management of the Fund;
          Portfolio Transactions

Item 5A.  Management's Discussion of Fund Performance**

Item 6.   Capital Stock and Other Securities -- Purchase of Shares; Redemption
          of Shares; Shareholder Services; Valuation of Shares; Dividends and
          Capital Gains Distributions; Taxes; General Information

Item 7.   Purchase of Securities Being Offered -- Prospectus Summary; Cover
          Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.   Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
          Shareholder Services

Item 9.   Pending Legal Proceedings -- *


_______________________
*      Omitted since the answer is negative or the Item is not applicable. 
   
**     Information required by Item 5A is contained in the  1996 Annual Report
       to Shareholders, except for the following portfolios which were not in
       operation at December 31, 1996:  Mortgage-Backed Securities, China
       Growth and MicroCap Portfolios. Information required by Item 5A for the 
       aforementioned portfolios will be contained in the next Report to
       Shareholders following commencement of operations.
    
<PAGE>

 Form N-1A
Item Number    Location in Prospectus for the Technology Portfolio
- -----------    ---------------------------------------------------

Item 1.   Cover Page -- Cover Page

Item 2.   Synopsis -- Fund Expenses (Estimated)

Item 3.   Condensed Financial Information -- *

Item 4.   General Description of Registrant -- Prospectus Summary; Investment
          Objective and Policies; Additional Investment Information; Investment
          Limitations; General Information

Item 5.   Management of the Fund -- Prospectus Summary; Management of the Fund;
          Portfolio Transactions

Item 5A.  Management's Discussion of Fund Performance**

Item 6.   Capital Stock and Other Securities -- Purchase of Shares; Redemption
          of Shares; Shareholder Services; Valuation of Shares; Dividends and
          Capital Gains Distributions; Taxes; General Information

Item 7.   Purchase of Securities Being Offered -- Prospectus Summary; Cover
          Page; Purchase of Shares; Shareholder Services; Valuation of Shares

Item 8.   Redemption or Repurchase -- Prospectus Summary; Redemption of Shares;
          Shareholder Services

Item 9.   Pending Legal Proceedings -- *


_______________________
*      Omitted since the answer is negative or the Item is not applicable. 
   
**     Information required by Item 5A is contained in the  1996 Annual Report
       to Shareholders, except for the following portfolios which were not in
       operation at December 31, 1996:  Mortgage-Backed Securities, China
       Growth and MicroCap Portfolios. Information required by Item 5A for the 
       aforementioned portfolios will be contained in the next Report to
       Shareholders following commencement of operations.
    
<PAGE>

PART B -       INFORMATION REQUIRED IN A STATEMENT OF ADDITIONAL INFORMATION


 Form N-1A
Item Number    Location in Statement of Additional Information for the Fixed
- -----------    Income, Global Fixed Income, Municipal Bond, Mortgage-Backed
               Securities, High Yield, Money Market, Municipal Money Market,
               Small Cap Value Equity, Value Equity, Balanced, Active Country
               Allocation, Gold, Global Equity, International Equity,
               International Magnum, International Small Cap, Asian Equity,
               European Equity, Japanese Equity, Latin American, Emerging
               Markets, Emerging Markets Debt, China Growth, Equity Growth,
               Emerging Growth, MicroCap, Aggressive Equity and U.S. Real Estate
               Portfolios
               -----------------------------------------------------------------

Item 10.  Cover Page -- Cover Page

Item 11.  Table of Contents -- Cover Page

Item 12.  General Information and History -- * 

Item 13.  Investment Objective and Policies -- Investment Objectives and
          Policies; Investment Limitations

Item 14.  Management of the Fund -- Management of the Fund

Item 15.  Control Persons and Principal Holders of Securities -- Management of
          the Fund; General Information

Item 16.  Investment Advisory and Other Services -- Management of the Fund


Item 17.  Brokerage Allocation -- * 

Item 18.  Capital Stock and Other Securities -- General Information

Item 19.  Purchase, Redemption and Pricing of Securities Being Offered --
          Purchase of Shares; Redemption of Shares; Net Asset Value; General
          Information

Item 20.  Tax Status -- Federal Tax Treatment of Forward Currency and Futures
          Contracts

Item 21.  Underwriters -- *

Item 22.  Calculation of Performance Data -- Performance Information

Item 23.  Financial Statements -- Financial Statements

_______________________
*    Omitted since the answer is negative or the Item is not applicable.


                                        
<PAGE>


 Form N-1A
Item Number    Location in Statement of Additional Information for the
- -----------    Technology Portfolio
               ----------------------------------------------------------------

Item 10.  Cover Page -- Cover Page

Item 11.  Table of Contents -- Cover Page

Item 12.  General Information and History -- *

Item 13.  Investment Objective and Policies -- Investment Objective and
          Policies; Investment Limitations

Item 14.  Management of the Fund-- Management of the Fund

Item 15.  Control Persons and Principal Holders of Securities -- Management of
          the Fund; General Information

Item 16.  Investment Advisory and Other Services-- Management of the Fund

Item 17.  Brokerage Allocation -- *

Item 18.  Capital Stock and Other Securities -- General Information

Item 19.  Purchase, Redemption and Pricing of Securities Being Offered --
          Purchase of Shares; Redemption of Shares; Net Asset Value; General
          Information

Item 20.  Tax Status -- Federal Tax Treatment of Forward Currency and Futures
          Contracts

Item 21.  Underwriters -- *

Item 22.  Calculation of Performance Data -- Performance Information

Item 23.  Financial Statements


Part C    Other Information
- ------    -----------------


          Part C contains the information required by the terms contained
          therein under the items set forth in the form.


_______________________
*    Omitted since the answer is negative or the Item is not applicable.
   
    
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
 -----------------------------------------------------------------------------
 
                             FIXED INCOME PORTFOLIO
                            MUNICIPAL BOND PORTFOLIO
                      MORTGAGE-BACKED SECURITIES PORTFOLIO
                             MONEY MARKET PORTFOLIO
                        MUNICIPAL MONEY MARKET PORTFOLIO
 
                               PORTFOLIOS OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
 
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
                                ----------------
 
   
    Morgan Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company or mutual fund, which offers redeemable shares in
a series of diversified and non-diversified investment portfolios
("portfolios"). The Fund is designed to provide clients with attractive
alternatives for meeting their investment needs. The Fund currently consists of
twenty-nine portfolios representing a broad range of investment choices. This
prospectus (the "Prospectus") pertains to the Class A and the Class B shares of
the Fixed Income, Municipal Bond and Mortgage-Backed Securities Portfolios (the
"Non-Money Portfolios") and to the Class A shares of the Money Market and
Municipal Money Market Portfolios (the "Money Portfolios") (each, a "Portfolio"
and collectively, the "Portfolios"). The Class A and Class B shares currently
offered by the Non-Money Portfolios have different minimum investment
requirements and fund expenses. Shares of the portfolios are offered with no
sales charge, exchange fee or redemption fee, (except that the International
Small Cap Portfolio may impose a transaction fee). The Mortgage-Backed
Securities Portfolio currently is not being offered.
    
 
    INVESTMENTS IN THE MONEY MARKET AND MUNICIPAL MONEY MARKET PORTFOLIOS ARE
NEITHER INSURED NOR GUARANTEED BY THE U.S. GOVERNMENT. THERE IS NO ASSURANCE
THAT THE MONEY MARKET AND MUNICIPAL MONEY MARKET PORTFOLIOS WILL BE ABLE TO
MAINTAIN A STABLE NET ASSET VALUE OF $1.00 PER SHARE.
 
    The Fund is designed to meet the investment needs of discerning investors
who place a premium on quality and personal service. With Morgan Stanley Asset
Management Inc. as Adviser and Administrator (the "Adviser" and the
"Administrator") and with Morgan Stanley & Co. Incorporated ("Morgan Stanley")
as Distributor, the Fund makes available to institutional and high net worth
individual investors a series of portfolios which benefit from the investment
expertise and commitment to excellence associated with Morgan Stanley and its
affiliates.
 
    This Prospectus is designed to set forth concisely the information about the
Fund that a prospective investor should know before investing and it should be
retained for future reference. The Fund offers additional portfolios which are
described in other prospectuses and under "Prospectus Summary" below. The Fund
currently offers the following portfolios: (i) GLOBAL AND INTERNATIONAL EQUITY
- -- Active Country Allocation, Asian Equity, Emerging Markets, European Equity,
Global Equity, Gold, International Equity, International Magnum, International
Small Cap, Japanese Equity and Latin American Portfolios; (ii) U.S. EQUITY --
Aggressive Equity, Emerging Growth, Equity Growth, Small Cap Value Equity,
Technology, U.S. Real Estate and Value Equity Portfolios; (iii) EQUITY AND FIXED
INCOME -- Balanced Portfolio; (iv) FIXED INCOME -- Emerging Markets Debt, Fixed
Income, Global Fixed Income, High Yield and Municipal Bond Portfolios; and (v)
MONEY MARKET -- Money Market and Municipal Money Market Portfolios. Additional
information about the Fund is contained in a "Statement of Additional
Information" dated May 1, 1997, which is incorporated herein by reference. The
Statement of Additional Information and the prospectuses pertaining to the other
portfolios of the Fund are available upon request and without charge by writing
or calling the Fund at the address and telephone number set forth above.
THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES AND
EXCHANGE COMMISSION, NOR HAS THE SECURITIES AND EXCHANGE COMMISSION
       PASSED UPON THE ACCURACY OR ADEQUACY OF THIS PROSPECTUS.
               ANY REPRESENTATION TO THE CONTRARY IS A
                               CRIMINAL OFFENSE.
 
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1997.
<PAGE>
                                 FUND EXPENSES
 
    The following table illustrates the expenses and fees that a shareholder of
the Portfolios indicated below will incur:
 
<TABLE>
<CAPTION>
                                                                                            MORTGAGE-             MUNICIPAL
                                                                        FIXED    MUNICIPAL   BACKED      MONEY      MONEY
                                                                       INCOME      BOND     SECURITIES  MARKET     MARKET
SHAREHOLDER TRANSACTION EXPENSES                                      PORTFOLIO  PORTFOLIO  PORTFOLIO  PORTFOLIO  PORTFOLIO
- --------------------------------------------------------------------  ---------  ---------  ---------  ---------  ---------
<S>                                                                   <C>        <C>        <C>        <C>        <C>
Maximum Sales Load Imposed on Purchases
  Class A...........................................................    None       None       None       None       None
  Class B...........................................................    None       None       None        N/A        N/A
Maximum Sales Load Imposed on Reinvested Dividends
  Class A...........................................................    None       None       None       None       None
  Class B...........................................................    None       None       None        N/A        N/A
Deferred Sales Load
  Class A...........................................................    None       None       None       None       None
  Class B...........................................................    None       None       None        N/A        N/A
Redemption Fees
  Class A...........................................................    None       None       None       None       None
  Class B...........................................................    None       None       None        N/A        N/A
Exchange Fees
  Class A...........................................................    None       None       None       None       None
  Class B...........................................................    None       None       None        N/A        N/A
</TABLE>
 
   
<TABLE>
<CAPTION>
                                                                          MORTGAGE-             MUNICIPAL
                                                     FIXED     MUNICIPAL   BACKED     MONEY      MONEY
                                                     INCOME      BOND     SECURITIES  MARKET     MARKET
ANNUAL FUND OPERATING EXPENSES                      PORTFOLIO  PORTFOLIO  PORTFOLIO+ PORTFOLIO  PORTFOLIO
- --------------------------------------------------  --------   --------   --------   --------   --------
(AS A PERCENTAGE OF AVERAGE NET ASSETS)
<S>                                                 <C>        <C>        <C>        <C>        <C>
Management Fee (Net of Fee Waivers)*
  Class A.........................................    0.20%      0.07%      0.20%+     0.30%**    0.30%**
  Class B.........................................    0.20%      0.07%      0.20%+     N/A        N/A
12b-1 Fees
  Class A.........................................    None       None        None+     None       None
  Class B.........................................    0.15%***   0.25%      0.25%+     N/A        N/A
Other Expenses
  Class A.........................................    0.25%      0.38%      0.25%+     0.22%      0.23%
  Class B.........................................    0.25%      0.38%      0.25%+     N/A        N/A
                                                    --------   --------   --------   --------   --------
Total Operating Expenses (Net of Fee Waivers)*
  Class A.........................................    0.45%      0.45%      0.45%+     0.52%**    0.53%**
  Class B.........................................    0.60%      0.70%      0.70%+     N/A        N/A
                                                    --------   --------   --------   --------   --------
                                                    --------   --------   --------   --------   --------
</TABLE>
    
 
- ------------------------------
   
+Estimated.
    
   
*The Adviser has agreed to waive its management fees and/or reimburse each
 Portfolio, if necessary, if such fees would cause the total annual operating
 expenses of the Portfolios to exceed a specified percentage of their respective
 average daily net assets. As a result of these reductions, the Management Fees
 stated above are lower than the contractual fees stated under "Management of
 the Fund." The Adviser reserves the right to terminate any of its fee waivers
 and/or expense reimbursements at any time in its sole discretion. For further
 information on Fund expenses see "Management of the Fund." Set forth below, for
 each Portfolio as applicable, are the management fees and total operating
 expenses absent such fee waivers and/or expense reimbursements as a percent of
 average daily net assets of the Class A shares of the Portfolios and Class B
 shares of the Non-Money Portfolios, respectively.
    
 
                                       2
<PAGE>
 
   
<TABLE>
<CAPTION>
                                                                                   TOTAL OPERATING EXPENSES
                                                                                      ABSENT FEE WAIVERS
                                                            MANAGEMENT FEES      ----------------------------
PORTFOLIO                                                 ABSENT FEE WAIVERS        CLASS A        CLASS B
- ------------------------------------------------------  -----------------------  -------------  -------------
<S>                                                     <C>                      <C>            <C>
Fixed Income..........................................             0.35%              0.60%           0.74%
Municipal Bond........................................             0.35%              0.73%           0.98%
Mortgage-Backed Securities............................             0.35%              0.60%           0.85%
Money Market..........................................             0.30%              0.52%          N/A
Municipal Money Market................................             0.30%              0.53%          N/A
</TABLE>
    
 
- ------------------------
   
 **No fee waiver or expense reimbursement is in effect for this Portfolio.
    
***The Distributor has agreed to waive 0.10% of the 0.25% distribution fee it is
   entitled to receive from this Portfolio.
 
    The purpose of the table above is to assist the investor in understanding
the various expenses that an investor in the Portfolios will bear directly or
indirectly. Expenses and fees are based on actual figures for the fiscal year
ended December 31, 1996. Expenses for the Mortgage-Backed Securities Portfolio
are based on estimates and assume that the average daily net assets of the
Mortgage-Backed Securities Portfolio will be $50,000,000. Due to the continuous
nature of Rule 12b-1 fees, long term Class B shareholders may pay more than the
equivalent of the maximum front-end sales charges otherwise permitted by the
National Association of Securities Dealers, Inc. ("NASD") Conduct Rules.
 
    The following example illustrates the expenses that you would pay on a
$1,000 investment assuming (1) a 5% annual rate of return and (2) redemption at
the end of each time period. As noted in the table above, the Portfolios charge
no redemption fees of any kind. The following example is based on total
operating expenses of the Portfolios after fee waivers.
 
   
<TABLE>
<CAPTION>
                                           1       3       5      10
                                         YEAR    YEARS   YEARS   YEARS
                                         -----   -----   -----   -----
<S>                                      <C>     <C>     <C>     <C>
Fixed Income Portfolio
  Class A.............................   $  5    $ 14    $ 25    $ 57
  Class B.............................      6      19      33      75
Municipal Bond Portfolio
  Class A.............................      5      14      25      57
  Class B.............................      7      22      39      87
Mortgage-Backed Securities Portfolio
  Class A.............................      5      14     *       *
  Class B.............................      7      22     *       *
Money Market Portfolio
  Class A.............................      5      17      29      65
Municipal Money Market Portfolio
  Class A.............................      5      17      30      66
</TABLE>
    
 
- ------------------------
 
* Because the Mortgage-Backed Securities Portfolio was not operational as of the
  Fund's fiscal year end, the Fund has not projected expenses beyond the
  three-year period shown.
 
    THIS EXAMPLE SHOULD NOT BE CONSIDERED A REPRESENTATION OF PAST OR FUTURE
EXPENSES OR PERFORMANCE. ACTUAL EXPENSES MAY BE GREATER OR LESS THAN THOSE
SHOWN.
 
                                       3
<PAGE>
                              FINANCIAL HIGHLIGHTS
 
   
    The following tables provide financial highlights for the Class A and Class
B shares of the Fixed Income and Municipal Bond Portfolios and the Class A
shares of the Money Market and Municipal Money Market Portfolios for each of the
periods presented. The audited financial highlights for the Portfolios' shares
for each of the periods presented are part of the Fund's financial statements
which appear in the Fund's December 31, 1996 Annual Report to Shareholders and
which are incorporated by reference in the Fund's Statement of Additional
Information. The Portfolios' financial highlights for each of the periods
presented have been audited by Price Waterhouse LLP, whose unqualified report
thereon is also incorporated by reference in the Statement of Additional
Information. Additional performance information is included in the Annual
Report. The Annual Report and the financial statements therein, along with the
Statement of Additional Information, are available at no cost from the Fund at
the address and telephone number noted on the cover page of this Prospectus. The
Mortgage-Backed Securities Portfolio was not operational as of December 31,
1996. After October 31, 1992, the Fund changed its fiscal year end to December
31. The following information should be read in conjunction with the financial
statements and notes thereto.
    
 
                                       4
<PAGE>
                             FIXED INCOME PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                                                    CLASS B
                                                                                                   ---------
                                                                                                    PERIOD
                                                                                                     FROM
                                                          CLASS A                                   JANUARY
                           ---------------------------------------------------------------------      2,
                                                                              TWO                   1996***
                             YEAR        YEAR        YEAR        YEAR       MONTHS       YEAR         TO
                             ENDED       ENDED       ENDED       ENDED       ENDED       ENDED     DECEMBER
                           DECEMBER    DECEMBER    DECEMBER    DECEMBER    DECEMBER     OCTOBER       31,
                           31, 1996    31, 1995    31, 1994    31, 1993    31, 1992    31, 1992      1996
                           ---------   ---------   ---------   ---------   ---------   ---------   ---------
<S>                        <C>         <C>         <C>         <C>         <C>         <C>         <C>
NET ASSET VALUE,
 BEGINNING OF PERIOD.....  $ 10.81     $  9.82     $ 11.05     $ 10.93     $ 10.92     $ 10.55     $ 10.81
                           ---------   ---------   ---------   ---------   ---------   ---------   ---------
                           ---------   ---------   ---------   ---------   ---------   ---------   ---------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment
   Income (1)............     0.67        0.72        0.59        0.54        0.10        0.69        0.64
  Net Realized and
   Unrealized Gain (Loss)
   on Investments........    (0.20)       1.06       (0.92)       0.41        0.01        0.39      (0.19)
                           ---------   ---------   ---------   ---------   ---------   ---------   ---------
    Total from Investment
     Operations..........     0.47        1.78       (0.33)       0.95        0.11        1.08        0.45
                           ---------   ---------   ---------   ---------   ---------   ---------   ---------
DISTRIBUTIONS
  Net Investment
   Income................    (0.70)      (0.79)      (0.53)      (0.56)      (0.10)      (0.69)      (0.68)
  In Excess of Net
   Investment Income.....    (0.00)+        --          --       (0.01)         --          --          --
  Net Realized Gain......       --          --       (0.37)      (0.26)         --       (0.02)         --
  In Excess of Net
   Realized Gain.........       --          --       (0.00)+        --          --          --          --
                           ---------   ---------   ---------   ---------   ---------   ---------   ---------
    Total
     Distributions.......    (0.70)      (0.79)      (0.90)      (0.83)      (0.10)      (0.71)      (0.68)
                           ---------   ---------   ---------   ---------   ---------   ---------   ---------
NET ASSET VALUE, END OF
 PERIOD..................  $ 10.58     $ 10.81     $  9.82     $ 11.05     $ 10.93     $ 10.92     $ 10.58
                           ---------   ---------   ---------   ---------   ---------   ---------   ---------
                           ---------   ---------   ---------   ---------   ---------   ---------   ---------
TOTAL RETURN.............     4.61%      18.76%      (3.10)%      9.07%       1.02%      10.61%       4.35%
                           ---------   ---------   ---------   ---------   ---------   ---------   ---------
                           ---------   ---------   ---------   ---------   ---------   ---------   ---------
RATIOS AND SUPPLEMENTAL
 DATA:
  Net Assets, End of
   Period (Thousands)....  $130,733    $165,527    $209,331    $240,668    $154,210    $146,546    $ 1,462
  Ratio of Expenses to
   Average Net
   Assets (1)............     0.45%       0.45%       0.45%       0.45%       0.45%**     0.45%       0.60%**
  Ratio of Net Investment
   Income to Average Net
   Assets (1)............     6.30%       6.85%       5.73%       4.97%       5.56%**     6.59%       6.15%**
  Portfolio Turnover
   Rate..................      183%        172%        388%        240%         15%        105%        183%
- ------------------------------
(1) Effect of voluntary
    expense limitation
    during the period:
     Per share benefit to
      net investment
      income.............    $0.02       $0.01       $0.01       $0.02       $0.01       $0.02       $0.01
   Ratios before expense
    limitation:
     Expenses to Average
      Net Assets.........     0.60%       0.59%       0.58%       0.60%       0.75%**     0.59%       0.74%**
     Net Investment
      Income to Average
      Net Assets.........     6.15%       6.71%       5.60%       4.82%       5.26%**     6.45%       6.01%**
</TABLE>
    
 
   
 ** Annualized.
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
  + Amount is less than $0.01 per share.
 
                                       5
<PAGE>
                            MUNICIPAL BOND PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                              CLASS A                 CLASS B
                                                                    ----------------------------    ------------
                                                                                    PERIOD FROM     PERIOD FROM
                                                                                    JANUARY 18,      JANUARY 2,
                                                                     YEAR ENDED       1995* TO       1996*** TO
                                                                    DECEMBER 31,    DECEMBER 31,    DECEMBER 31,
                                                                        1996            1995            1996
                                                                    ------------    ------------    ------------
<S>                                                                 <C>             <C>             <C>
NET ASSET VALUE, BEGINNING OF PERIOD.............................   $    10.37      $    10.00      $    10.37
                                                                    ------------    ------------    ------------
                                                                    ------------    ------------    ------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)......................................         0.49            0.44            0.44
  Net Realized and Unrealized Gain (Loss) on Investments.........        (0.12)           0.42           (0.08)
                                                                    ------------    ------------    ------------
    Total from Investment Operations.............................         0.37            0.86            0.36
                                                                    ------------    ------------    ------------
DISTRIBUTIONS
  Net Investment Income..........................................        (0.49)          (0.45)          (0.49)
  In Excess of Net Investment Income.............................       --               (0.00)+        --
  Net Realized Gain..............................................       --               (0.04)         --
                                                                    ------------    ------------    ------------
    Total Distributions..........................................        (0.49)          (0.49)          (0.49)
                                                                    ------------    ------------    ------------
NET ASSET VALUE, END OF PERIOD...................................   $    10.25      $    10.37      $    10.24
                                                                    ------------    ------------    ------------
                                                                    ------------    ------------    ------------
TOTAL RETURN.....................................................         3.67%           8.80%           3.55%
                                                                    ------------    ------------    ------------
                                                                    ------------    ------------    ------------
RATIOS AND SUPPLEMENTAL DATA:
  Net Assets, End of Period (Thousands)..........................   $   40,227      $   45,869      $       69
  Ratio of Expenses to Average Net Assets (1)....................         0.45%           0.45%**         0.70%**
  Ratio of Net Investment Income to Average Net Assets (1).......         4.77%           4.61%**         4.56%**
  Portfolio Turnover Rate........................................           45%            180%             45%
</TABLE>
    
 
- ------------------------------
 
   
<TABLE>
<C>  <S>                                                            <C>             <C>             <C>
(1)  Effect of voluntary expense limitation during the period:
       Per share benefit to net investment income................        $0.03           $0.03           $0.03
     Ratios before expense limitation:
       Expenses to Average Net Assets............................         0.73%           0.73%**         0.98%**
       Net Investment Income to Average Net Assets...............         4.50%           4.33%**         4.28%**
</TABLE>
    
 
   
  * Commencement of Operations.
    
 ** Annualized.
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
  + Amount is less than $0.01 per share.
 
                                       6
<PAGE>
                             MONEY MARKET PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                           TWO      YEAR
                                                               YEAR      MONTHS    ENDED
                      YEAR ENDED   YEAR ENDED   YEAR ENDED     ENDED      ENDED    OCTOBER
                       DECEMBER     DECEMBER     DECEMBER    DECEMBER   DECEMBER    31,
                       31, 1996     31, 1995     31, 1994    31, 1993   31, 1992    1992
                      -----------  -----------  -----------  ---------  ---------  ------
<S>                   <C>          <C>          <C>          <C>        <C>        <C>
NET ASSET VALUE,
 BEGINNING OF
 PERIOD.............  $  1.000     $  1.000     $  1.000     $  1.000   $  1.000   $1.000
                      -----------  -----------  -----------  ---------  ---------  ------
                      -----------  -----------  -----------  ---------  ---------  ------
INCOME FROM
 INVESTMENT
 OPERATIONS
  Net Investment
   Income (1).......     0.049        0.054        0.040        0.027      0.005   0.039
                      -----------  -----------  -----------  ---------  ---------  ------
DISTRIBUTIONS
  Net Investment
   Income...........    (0.049)      (0.054)      (0.040)      (0.027)    (0.005)  (0.039)
  In Excess of Net
   Investment
   Income...........        --           --           --        0.000+        --      --
                      -----------  -----------  -----------  ---------  ---------  ------
    Total
    Distributions...    (0.049)      (0.054)      (0.040)      (0.027)    (0.005)  (0.039)
                      -----------  -----------  -----------  ---------  ---------  ------
NET ASSET VALUE, END
 OF PERIOD..........  $  1.000     $  1.000     $  1.000     $  1.000   $  1.000   $1.000
                      -----------  -----------  -----------  ---------  ---------  ------
                      -----------  -----------  -----------  ---------  ---------  ------
TOTAL RETURN........      5.03%        5.51%        3.84%        2.76%      0.50%   3.77%
                      -----------  -----------  -----------  ---------  ---------  ------
                      -----------  -----------  -----------  ---------  ---------  ------
RATIOS AND
 SUPPLEMENTAL DATA:
  Net Assets, End of
   Period
   (Thousands)......  $1,284,633   $836,693     $690,503     $657,163   $599,172   $612,968
  Ratio of Expenses
   to Average Net
   Assets (1).......      0.52%        0.51%        0.49%        0.53%      0.55%**  0.52%
  Ratio of Net
   Investment Income
   to Average Net
   Assets (1).......      4.92%        5.37%        3.77%        2.71%      3.11%**  3.74%
- ------------------------------
(1) Effect of
    voluntary
    expense
    limitation
    during the
    period:
     Per share
      benefit to net
      investment
      income........       N/A          N/A          N/A       $0.000+    $0.000+    N/A
   Ratios before
    expense
    limitation:
     Expenses to
      Average Net
      Assets........       N/A          N/A          N/A         0.54%      0.59%**   N/A
     Net Investment
      Income to
      Average Net
      Assets........       N/A          N/A          N/A         2.70%      3.07%**   N/A
</TABLE>
    
 
   
** Annualized.
    
 
 + Amount if less than $0.001 per share.
 
                                       7
<PAGE>
                        MUNICIPAL MONEY MARKET PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                           TWO
                                                                         MONTHS     YEAR
                                                               YEAR       YEAR     ENDED
                      YEAR ENDED   YEAR ENDED   YEAR ENDED     ENDED      ENDED    OCTOBER
                       DECEMBER     DECEMBER     DECEMBER    DECEMBER   DECEMBER    31,
                       31, 1996     31, 1995     31, 1994    31, 1993   31, 1992    1992
                      -----------  -----------  -----------  ---------  ---------  ------
<S>                   <C>          <C>          <C>          <C>        <C>        <C>
NET ASSET VALUE,
 BEGINNING OF
 PERIOD.............  $  1.000     $  1.000     $  1.000     $  1.000   $  1.000   $1.000
                      -----------  -----------  -----------  ---------  ---------  ------
                      -----------  -----------  -----------  ---------  ---------  ------
INCOME FROM
 INVESTMENT
 OPERATIONS
  Net Investment
   Income (1).......     0.030        0.034        0.020        0.019      0.004   0.026
                      -----------  -----------  -----------  ---------  ---------  ------
DISTRIBUTIONS
  Net Investment
   Income...........    (0.030)      (0.034)      (0.020)      (0.019)    (0.004)  (0.026)
  In Excess of Net
   Investment
   Income...........        --           --           --       (0.000)+       --      --
                      -----------  -----------  -----------  ---------  ---------  ------
    Total
    Distributions...    (0.030)      (0.034)      (0.020)      (0.019)    (0.004)  (0.026)
                      -----------  -----------  -----------  ---------  ---------  ------
NET ASSET VALUE, END
 OF PERIOD..........  $  1.000     $  1.000     $  1.000     $  1.000   $  1.000   $1.000
                      -----------  -----------  -----------  ---------  ---------  ------
                      -----------  -----------  -----------  ---------  ---------  ------
TOTAL RETURN........      3.02%        3.44%        2.44%        1.91%      0.37%   2.74%
                      -----------  -----------  -----------  ---------  ---------  ------
                      -----------  -----------  -----------  ---------  ---------  ------
RATIOS AND
 SUPPLEMENTAL DATA:
  Net Assets, End of
   Period
   (Thousands)......  $721,410     $451,519     $359,444     $266,524   $208,866   $206,691
  Ratio of Expenses
   to Average Net
   Assets (1).......      0.53%        0.52%        0.51%        0.54%      0.57%**  0.55%
  Ratio of Net
   Investment Income
   to Average Net
   Assets (1).......      2.98%        3.38%        2.42%        1.89%      2.31%**  2.66%
- ------------------------------
(1) Effect of
    voluntary
    expense
    limitation dur-
    ing the period:
     Per share
      benefit to net
      investment
      income........       N/A          N/A          N/A       $0.000+    $0.000+    N/A
   Ratios before
    expense
    limitation:
     Expenses to
      Average Net
      Assets........       N/A          N/A          N/A         0.56%      0.67%**   N/A
     Net Investment
      Income to
      Average Net
      Assets........       N/A          N/A          N/A         1.87%      2.21%**   N/A
</TABLE>
    
 
   
** Annualized.
    
 
   
 + Amount is less than $0.001 per share.
    
 
                                       8
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
 
    The Fund consists of twenty-nine portfolios, offering institutional and high
net worth individual investors a broad range of investment choices coupled with
the advantages of a no-load mutual fund with Morgan Stanley and its affiliates
providing customized services as Adviser, Administrator and Distributor. Each
portfolio offers Class A shares and, except the International Small Cap, Money
Market and Municipal Money Market Portfolios, also offers Class B shares. Each
portfolio has its own investment objective and policies designed to meet its
specific goals. The investment objective of each Portfolio described in this
Prospectus is as follows:
 
    - The FIXED INCOME PORTFOLIO seeks to produce a high total return consistent
      with the preservation of capital by investing in a diversified portfolio
      of fixed income securities.
 
    - The MUNICIPAL BOND PORTFOLIO seeks to produce a high level of current
      income consistent with preservation of principal by investing primarily in
      municipal obligations, the interest on which is exempt from federal income
      tax.
 
    - The MORTGAGE-BACKED SECURITIES PORTFOLIO seeks to produce as high a level
      of current income as is consistent with the preservation of capital by
      investing primarily in a variety of investment-grade mortgage-backed
      securities.
 
    - The MONEY MARKET PORTFOLIO seeks to maximize current income and preserve
      capital while maintaining high levels of liquidity through investing in
      high quality money market instruments with remaining maturities of one
      year or less.
 
    - The MUNICIPAL MONEY MARKET PORTFOLIO seeks to maximize current tax-exempt
      income and preserve capital while maintaining high levels of liquidity
      through investing in high quality money market instruments with remaining
      maturities of one year or less which are exempt from federal income tax.
 
    The other portfolios of the Fund are described in other prospectuses which
may be obtained from the Fund at the address and telephone number noted on the
cover page of this Prospectus. The investment objectives of these other
portfolios are listed below:
 
    GLOBAL AND INTERNATIONAL EQUITY:
 
    - The ACTIVE COUNTRY ALLOCATION PORTFOLIO seeks long-term capital
      appreciation by investing in accordance with country weightings determined
      by the Adviser in equity securities of non-U.S. issuers which, in the
      aggregate, replicate broad country indices.
 
    - The ASIAN EQUITY PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of Asian issuers.
 
    - The CHINA GROWTH PORTFOLIO seeks to provide long-term capital appreciation
      by investing primarily in equity securities of issuers in The People's
      Republic of China, Hong Kong and Taiwan.
 
    - The EMERGING MARKETS PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of emerging country issuers.
 
    - The EUROPEAN EQUITY PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of European issuers.
 
                                       9
<PAGE>
    - The GLOBAL EQUITY PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of issuers throughout the world,
      including U.S. issuers.
 
    - The GOLD PORTFOLIO seeks long-term capital appreciation by investing
      primarily in equity securities of foreign and domestic issuers engaged in
      gold-related activities.
 
    - The INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of non-U.S. issuers.
 
    - The INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of non-U.S. issuers domiciled in
      EAFE countries.
 
    - The INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital appreciation
      by investing primarily in equity securities of non-U.S. issuers with
      equity market capitalizations of less than $1 billion.
 
    - The JAPANESE EQUITY PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of Japanese issuers.
 
   
    - The LATIN AMERICAN PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of Latin American issuers and,
      from time to time, debt securities issued or guaranteed by Latin American
      governments or governmental entities.
    
 
    U.S. EQUITY:
 
    - The AGGRESSIVE EQUITY PORTFOLIO seeks capital appreciation by investing
      primarily in corporate equity and equity-linked securities.
 
    - The EMERGING GROWTH PORTFOLIO seeks long-term capital appreciation by
      investing primarily in growth-oriented equity securities of small- to
      medium-sized corporations.
 
    - The EQUITY GROWTH PORTFOLIO seeks long-term capital appreciation by
      investing in growth-oriented equity securities of medium and large
      capitalization companies.
 
    - The MICROCAP PORTFOLIO seeks long-term capital appreciation by investing
      primarily in growth-oriented equity securities of small corporations.
 
    - The SMALL CAP VALUE EQUITY PORTFOLIO seeks high long-term total return by
      investing in undervalued equity securities of small- to medium-sized
      companies.
 
    - The TECHNOLOGY PORTFOLIO seeks long-term capital appreciation by investing
      primarily in equity securities of companies that, in the opinion of the
      Portfolio's investment adviser, are expected to be benefit from their
      involvement in technology and technology-related industries.
 
    - The U.S. REAL ESTATE PORTFOLIO seeks to provide above average current
      income and long-term capital appreciation by investing primarily in equity
      securities of companies in the U.S. real estate industry, including real
      estate investment trusts.
 
    - The VALUE EQUITY PORTFOLIO seeks high total return by investing in equity
      securities which the Adviser believes to be undervalued relative to the
      stock market in general at the time of purchase.
 
    EQUITY AND FIXED INCOME:
 
    - The BALANCED PORTFOLIO seeks high total return while preserving capital by
      investing in a combination of undervalued equity securities and fixed
      income securities.
 
                                       10
<PAGE>
    FIXED INCOME:
 
    - The EMERGING MARKETS DEBT PORTFOLIO seeks high total return by investing
      primarily in debt securities of government, government-related and
      corporate issuers located in emerging countries.
 
    - The GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real rate
      of return while preserving capital by investing in fixed income securities
      of issuers throughout the world, including U.S. issuers.
 
    - The HIGH YIELD PORTFOLIO seeks to maximize total return by investing in a
      diversified portfolio of high yield fixed income securities that offer a
      yield above that generally available on debt securities in the three
      highest rating categories of the recognized rating services.
 
   THE CHINA GROWTH, MICROCAP AND MORTGAGE-BACKED SECURITIES PORTFOLIOS ARE
   CURRENTLY NOT BEING OFFERED.
 
INVESTMENT MANAGEMENT
 
   
    Morgan Stanley Asset Management Inc., a wholly owned subsidiary of Morgan
Stanley Group Inc., which, together with its affiliated asset management
companies, at March 31, 1997 had in excess of $118 billion in assets under
management as an investment manager or as a fiduciary adviser, acts as
investment adviser to the Fund and each of its portfolios. See "Management of
the Fund -- Investment Adviser" and "Management of the Fund -- Administrator."
    
 
HOW TO INVEST
 
   
    Class A shares of each Portfolio are offered directly to investors at net
asset value with no sales commission or 12b-1 charges. Class B shares of each
Non-Money Portfolio are offered at net asset value with no sales commission, but
with a 12b-1 fee, which is accrued daily and paid quarterly, equal to 0.25% of
the Class B shares average daily net assets on an annualized basis. The
Distributor has agreed to waive 0.10% of the 0.25% 12b-1 fee with respect to the
Fixed Income Portfolio. Share purchases may be made by sending investments
directly to the Fund or through the Distributor. The minimum initial investment,
generally, is $500,000 for Class A shares of each Portfolio and $100,000 for
Class B shares of each Non-Money Portfolio. The minimum initial investment
amount is reduced for certain categories of investors. For additional
information on how to purchase shares and minimum initial investments, see
"Purchase of Shares."
    
 
HOW TO REDEEM
 
    Shares of each Portfolio may be redeemed at any time, without cost, at the
net asset value per share of shares of the applicable class next determined
after receipt of the redemption request. The redemption price may be more or
less than the purchase price. Certain redemptions that cause the value of an
account to remain for a continuous 60-day period below the minimum investment
amount for Class A shares or Class B shares may result in involuntary redemption
or automatic conversion. For additional information on how to redeem shares and
involuntary redemption or conversion, see "Purchase of Shares -- Minimum Account
Sizes and Involuntary Redemption of Shares" and "Redemption of Shares."
 
                                       11
<PAGE>
RISK FACTORS
 
   
    The investment policies of each of the Portfolios entail certain risks and
considerations of which an investor should be aware. The Fixed Income and Money
Market Portfolios may invest in securities of foreign issuers, which are subject
to certain risks not typically associated with U.S. securities. In addition,
each Portfolio may invest in repurchase agreements, lend its portfolio
securities and purchase securities on a when-issued or delayed delivery basis.
The Money Market Portfolio may invest in reverse repurchase agreements. Each
Non-Money Portfolio may invest in certain derivatives, including futures
contracts and options on futures contracts and, in the case of the Fixed Income
Portfolio, options. These investments entail certain costs and risks, including
imperfect correlation between the value of securities held by a Portfolio and
the value of the particular derivative instrument, and the risk that a Portfolio
could not close out a derivatives position when it would be most advantageous to
do so. The Fixed Income Portfolio may invest in foreign currency forward
contracts to hedge currency risks associated with investment in non-U.S. dollar
denominated securities. The Municipal Money Market Portfolio may invest in
"puts" on municipal bonds or notes and the Municipal Bond and Municipal Money
Market Portfolios may invest up to 20% of such Portfolios' total assets in
taxable securities. Each of these investment strategies involves specific risks
which are described under "Investment Objectives and Policies" and "Additional
Investment Information."
    
 
                                       12
<PAGE>
                       INVESTMENT OBJECTIVES AND POLICIES
 
    The investment objective of each Portfolio is described below, together with
the policies the Portfolios employ in their efforts to achieve these objectives.
Each Portfolio's investment objective is a fundamental policy which may not be
changed without the approval of a majority of the Portfolio's outstanding voting
securities. There is no assurance that the Portfolios will attain their
objectives. In addition to the investments and strategies described below, the
Portfolios may invest in certain securities and obligations as set forth in
"Additional Investment Information" below and as described under "Investment
Objectives and Policies" in the Statement of Additional Information. The
investment policies described below are not fundamental policies unless
otherwise noted and may be changed without shareholder approval.
 
THE FIXED INCOME PORTFOLIO
 
    The Fixed Income Portfolio seeks to produce a high total return consistent
with the preservation of capital by investing primarily in a diversified
portfolio of U.S. Government securities, corporate bonds (including
competitively priced Eurodollar bonds), mortgage-backed securities and other
fixed income securities, such as certificates of deposit and short-term money
market instruments. Short- and intermediate-term bonds form the core of the
Portfolio, and long-term bonds (i.e., those with maturities over ten years) are
purchased on a short-term opportunistic basis when the Adviser believes they
will enhance return without significantly increasing risk. The Adviser sets an
annual target rate of return for the Portfolio based on current and projected
market and economic conditions and manages the Portfolio conservatively --
primarily through gradual shifts in maturities in attempting to achieve this
target rate.
 
    The Portfolio emphasizes investments in U.S. Government and mortgage-backed
securities. Typically, between 50% and 75% of the Portfolio's total assets will
be invested in these securities. When corporate bonds are purchased, they will
generally be rated in the two highest rating categories by Moody's Investors
Service, Inc. ("Moody's") (Aaa or Aa) or Standard & Poor's Ratings Group ("S&P")
(AAA or AA). The Portfolio will not invest in a corporate bond if it is not
rated at least investment grade by either rating agency at the time of
investment. The Portfolio may invest up to 15% of its assets in fixed income
instruments denominated in foreign currencies and issued by corporate or
governmental issuers when the Adviser feels that the currency component and
underlying market characteristics of such obligations will add value to the
Portfolio.
 
THE MUNICIPAL BOND PORTFOLIO
 
    The Municipal Bond Portfolio seeks to produce a high level of current income
consistent with preservation of principal by investing in a portfolio consisting
primarily of intermediate- and long-term investment-grade Municipal Obligations,
the interest on which is exempt from federal income tax. "Municipal Obligations"
include notes, bonds and other securities issued by or on behalf of states,
territories and possessions of the U.S. and the District of Columbia, and their
political subdivisions, agencies and instrumentalities, on which the interest on
such Obligations is, in the opinion of counsel for the issuer or the Portfolio,
exempt from federal income tax.
 
    The Portfolio will invest only in Municipal Obligations if they are
investment grade securities. Investment grade securities are (i) bonds rated
within one of the four highest rating categories of Moody's (Aaa, Aa, A or Baa)
or S&P (AAA, AA, A or BBB); (ii) notes rated within one of the two highest
rating categories of Moody's (MIG1 or MIG2) or one of the two highest rating
categories of S&P (SP-1 or SP-2); (iii) commercial paper rated P-1 or
 
                                       13
<PAGE>
P-2 by Moody's or A-1 or A-2 by S&P; (iv) variable rate securities rated VMIG1
or VMIG2 by Moody's; and (v) unrated Municipal Obligations that the Adviser
believes are of comparable quality to securities in the foregoing rating
categories. Bonds rated Baa by Moody's or BBB by S&P have speculative
characteristics.
 
    Under normal market conditions, the Portfolio will invest at least 80% of
its net assets in Municipal Obligations (or futures contracts or options on
futures relating thereto), which at the time of investment are "investment grade
securities." This policy is fundamental and may not be changed without the
approval of a majority of the Portfolio's outstanding voting securities.
 
   
    Although there are no maturity restrictions on the Municipal Obligations in
which the Portfolio invests, it is currently anticipated that the average
maturity of the Portfolio will range between 7 and 20 years. Under normal market
conditions, at least 65% of the Portfolio's net assets will be invested in
Municipal Obligations having an initial maturity of more than one year. The
Adviser will actively manage the Portfolio, and adjust its average maturity
(including by the use of futures contracts and options on futures), depending on
its assessment of the relative yields available on securities of different
maturities and its expectations of future changes in interest rates. During
periods of rising interest rates and declining prices, the average maturity of
the Portfolio may be shorter, while during periods of declining interest rates
and rising prices, the Portfolio may have a longer average maturity.
    
 
    The Portfolio may also invest up to 20% of its net assets in cash, cash
equivalents, U.S. Government Securities and taxable corporate "investment grade
securities." U.S. Government Securities consist of direct obligations of the
U.S. Treasury and securities issued or guaranteed by agencies or
instrumentalities of the U.S. Government. Securities issued or guaranteed by
agencies or instrumentalities may be backed by the full faith and credit of the
United States (such as securities issued by the Government National Mortgage
Association ("GNMA")), or supported by the issuing agency's right to borrow from
the U.S. Treasury (such as securities issued by the Federal Home Loan Banks), or
backed only by the credit of the issuing instrumentality such as securities
issued by the Federal National Mortgage Association ("FNMA")). The Portfolio
will not invest more than 20% of its net assets in Municipal Obligations the
interest on which is subject to alternative minimum tax.
 
THE MORTGAGE-BACKED SECURITIES PORTFOLIO
 
    The Mortgage-Backed Securities Portfolio seeks to produce as high a level of
current income as is consistent with the preservation of capital by investing
primarily in mortgage-backed securities either (i) issued or guaranteed by the
U.S. Government or (ii) rated A or higher by Moody's or S&P or, if unrated,
determined by the Adviser to be of comparable quality.
 
    Mortgage-backed securities are securities that, directly or indirectly,
represent a participation in, or are secured by and payable from, mortgage loans
on real property, including governmental pass-through securities such as those
issued or guaranteed by GNMA, FNMA and the Federal Home Loan Mortgage
Corporation ("FHLMC"). Unlike GNMA certificates, FNMA and FHLMC obligations are
not backed by the full faith and credit of the U.S. government; they are
supported by the issuing instrumentality's right to borrow from the U.S.
Treasury. Each of GNMA, FNMA and FHLMC guarantees timely distributions of
interest to certificate holders and GNMA and FNMA also guarantee timely
distributions of scheduled principal. Mortgage-backed securities also include
collateralized mortgage obligations ("CMOs") and pass-through securities issued
or guaranteed by private sector entities. CMOs are debt obligations or
pass-through certificates issued by agencies or instrumentalities of the U.S.
government or by private originators or investors in mortgage loans. CMOs are
backed by
 
                                       14
<PAGE>
mortgage pass-through securities or whole loans and are evidenced by a series of
bonds or certificates issued in multiple classes or tranches. Private
pass-through securities are issued by private originators of or investors in
mortgage loans and are structured similarly to governmental pass-through
securities. Because private pass-throughs typically lack a guarantee by an
entity having the credit status of a governmental agency or instrumentality,
they are generally structured with one or more types of credit enhancement.
 
    The Portfolio will invest in mortgage-backed securities that are either (i)
issued or guaranteed by the U.S. Government or one of its agencies or
instrumentalities or (ii) at the time of investment rated within one of the
three highest rating categories of Moody's (Aaa, Aa or A) or S&P (AAA, AA or A),
or if unrated, determined by the Adviser to be of comparable quality. Under
normal market conditions, the Adviser expects that at least 75% of the
Portfolio's net assets will be invested in mortgage-backed securities issued or
guaranteed by the U.S. Government, its agencies or instrumentalities or rated
Aaa by Moody's or AAA by S&P. Up to 15% of the Portfolio's net assets may be
invested in mortgage-backed securities rated A by Moody's or S&P.
 
    The Adviser expects that short- and intermediate-term mortgage-backed
securities will form the core of the Portfolio, with long-term securities (i.e.,
with maturities over ten years) being purchased when the Adviser believes that
they will enhance return without significantly increasing risk. The Adviser sets
an annual target rate of return for the Portfolio based on current and projected
market and economic conditions and manages the Portfolio conservatively --
primarily through gradual shifts in maturities -- in attempting to achieve this
target rate.
 
    Due to the possibility that prepayments on home mortgages will alter cash
flow on mortgage-backed securities, it is not possible to determine in advance
the actual final maturity date or average life. Like bonds in general,
mortgage-backed securities will generally decline in price when interest rates
rise. Rising interest rates also tend to discourage refinancings of home
mortgages, with the result that the average life of mortgage-backed securities
held by a portfolio may be lengthened. This extension of average life causes the
market price of the securities to decrease further than if their average lives
were fixed. However, when interest rates fall, mortgage-backed securities may
not enjoy as large a gain in market value due to prepayment risk because
additional mortgage prepayments must be reinvested at lower interest rates.
Faster prepayment will shorten the average life and slower prepayments will
lengthen it. However, it is possible to determine what the range of that
movement could be and to calculate the effect that it will have on the price of
the security. In selecting these securities, the Adviser will look for those
securities that offer a higher yield to compensate for any variation in average
maturity.
 
THE MONEY MARKET PORTFOLIO
 
    The Money Market Portfolio seeks to maximize current income and preserve
capital while maintaining high levels of liquidity through investing in the
following high quality money market instruments which have remaining maturities
of one year or less. The Portfolio's average maturity (on a dollar-weighted
basis) will not exceed 90 days. The Portfolio is expected to maintain a net
asset value of $1.00 per share. There can be no assurance, however, that the
Portfolio will be successful in maintaining a net asset value of $1.00 per
share.
 
    U.S. GOVERNMENT OBLIGATIONS.  The Portfolio may invest in obligations issued
or guaranteed by the U.S. Government, such as U.S. Treasury securities and those
backed by the full faith and credit of the United States, such as obligations of
GNMA, the Farmers Home Administration and the Export-Import Bank. The Portfolio
may also invest in obligations issued or guaranteed by U.S. Government agencies
or instrumentalities where the
 
                                       15
<PAGE>
Portfolio must look principally to the issuing or guaranteeing agency for
ultimate repayment; some examples of agencies or instrumentalities issuing these
obligations are the Federal Farm Credit System and the Federal Home Loan Banks.
 
    MORTGAGE-BACKED SECURITIES.  Mortgage-backed securities in which the
Portfolio may invest, such as GNMA securities, differ from other fixed income
securities in that the principal is paid back by the borrower over the life of
the loan rather than returned in a lump sum at maturity. When prevailing
interest rates rise, the value of a GNMA security may decrease as with other
debt securities. When prevailing interest rates decline, however, the value of
GNMA securities may not rise as much as other debt securities because of the
prepayment feature of GNMA securities. Additionally, if a GNMA certificate is
purchased at a premium above its principal value because its fixed rate of
interest exceeds the prevailing level of yields, the decline in price to par may
result in a loss of the premium in the event of prepayment. Funds received from
prepayments may be reinvested at the prevailing interest rates which may be
lower than the rate of interest that had previously been earned.
 
   
    BANK OBLIGATIONS.  The Portfolio may invest in high quality U.S.
dollar-denominated negotiable certificates of deposit, time deposits, deposit
notes and bankers' acceptances of (i) banks, savings and loan associations and
savings banks which have more than $2 billion in total assets and are organized
under federal or state law, (ii) foreign branches of these banks ("Euros") and
(iii) U.S. branches of foreign banks of equivalent size ("Yankees"). The
Portfolio may also invest in U.S. dollar-denominated obligations of the
International Bank for Reconstruction and Development ("World Bank"). These
obligations are supported by appropriated but unpaid commitments of the World
Bank's member countries, and there is no assurance these commitments will be
undertaken or met in the future.
    
 
    COMMERCIAL PAPER; CORPORATE BONDS.  The Portfolio may invest in high quality
commercial paper and corporate bonds issued by U.S. corporations. The Portfolio
may also invest in commercial paper issued by foreign corporations if the issuer
is a direct subsidiary of a U.S. corporation, the obligation is U.S. dollar-
denominated and is not subject to foreign withholding tax, and the aggregate of
these foreign investments does not exceed 10% of the Portfolio's net assets.
 
    QUALITY INFORMATION.  The Portfolio uses the amortized cost method of
valuation in accordance with regulations issued by the Securities and Exchange
Commission (the "Commission"). Accordingly, the Portfolio will limit its
portfolio investments to those instruments that present minimal credit risks and
are of "eligible quality" as determined by the Adviser under the supervision of
the Board of Directors in accordance with regulations of the Commission, as they
may from time to time be amended. For this purpose, "eligible quality" means a
security rated (i) in one of the two highest rating categories by at least two
nationally recognized statistical rating organizations assigning a rating to the
security or issuer or, (ii) if only one rating organization assigned a rating,
by that rating organization or (iii) if unrated, of comparable quality as
determined by the Board of Directors. The Money Market Portfolio will not
purchase any bank or corporate obligation unless it is rated at least Aa or
Prime-1 by Moody's or AA or A-1 by S&P, or is deemed to be of comparable
quality.
 
    These standards must be satisfied at the time an investment is made. In the
event that an investment held by the Portfolio is assigned a lower rating or
ceases to be rated, the Adviser under the supervision of the Board of Directors,
will promptly reassess whether such security presents minimal credit risk and
whether the Portfolio
 
                                       16
<PAGE>
should continue to hold the security. If a portfolio security no longer presents
minimal credit risk or is in default, the Portfolio will dispose of the security
as soon as reasonably practicable unless the Board of Directors determines that
it is not in the best interests of the Portfolio to do so.
 
THE MUNICIPAL MONEY MARKET PORTFOLIO
 
    The Municipal Money Market Portfolio seeks to maximize current tax-exempt
income and preserve capital while maintaining high levels of liquidity through
investing in the following high quality municipal money market instruments
which, in the opinion of bond counsel for the issuer, earn interest exempt from
federal income tax. The Portfolio will purchase only securities having a
remaining maturity of one year or less. Under normal circumstances, the
Portfolio will invest at least 80% of its assets in tax-exempt municipal
securities. Additionally, the Portfolio will not purchase private activity
bonds, the interest from which is subject to the alternative minimum tax.
Interest on tax-exempt municipal securities may be subject to state and local
taxes. The Portfolio's average maturity (on a dollar-weighted basis) will not
exceed 90 days. The Portfolio is expected to maintain a net asset value of $1.00
per share. There can be no assurance, however, that the Portfolio will be
successful in maintaining a net asset value of $1.00 per share.
 
    MUNICIPAL BONDS.  The Portfolio may invest in bonds issued by or on behalf
of states, territories and possessions of the United States and its political
subdivisions, agencies, authorities and instrumentalities. These obligations may
be general obligation bonds secured by the issuer's pledge of its full faith,
credit and taxing power for the payment of principal and interest, or they may
be revenue bonds payable from specific revenue sources, but not generally backed
by the issuer's taxing power. These obligations include private activity bonds
where payment is the responsibility of the private industrial user of the
facility financed by the bonds. The Portfolio may invest more than 25% of its
total assets in private activity bonds (provided that the interest on such bonds
is not subject to the alternative minimum tax), but may not invest more than 25%
of its total assets in these bonds in projects of similar type or in the same
state.
 
    MUNICIPAL NOTES.  The Portfolio may also invest in municipal notes of
various types, including notes issued in anticipation of receipt of taxes, the
proceeds of the sale of bonds, other revenues or grant proceeds and project
notes, as well as municipal commercial paper and municipal demand obligations.
There may be no secondary market for project notes, and the Portfolio intends to
hold such notes until maturity. There is no specific percentage limitation on
these investments.
 
    QUALITY INFORMATION.  The Portfolio uses the amortized cost method of
valuation in accordance with regulations issued by the Commission. Accordingly,
the Portfolio will limit its portfolio investments to those instruments which
present minimal credit risk and which are of "eligible quality" as determined by
the Adviser under the supervision of the Board of Directors in accordance with
regulations of the Commission, as they may from time to time be amended. For
this purpose, "eligible quality" means a security rated (i) in one of the two
highest rating categories by at least two nationally recognized statistical
rating organizations assigning a rating to the security or issuer or, (ii) if
only one rating organization assigned a rating, by that rating organization or
(iii) if unrated, of comparable quality as determined by the Board of Directors.
The Municipal Money Market Portfolio will not purchase any municipal obligation
unless it is rated at least Aa, MIG-1 (or MIG-2 in the case of New York State
municipal notes), or Prime-1 by Moody's, or AA, SP-1 or A-1 by S&P, or is deemed
to be of comparable quality.
 
                                       17
<PAGE>
    These standards must be satisfied at the time an investment is made. In the
event that an investment held by the Portfolio is assigned a lower rating or
ceases to be rated, the Adviser under the supervision of the Board of Directors
will promptly reassess whether such security presents minimal credit risk and
whether the Portfolio should continue to hold the security. If a portfolio
security no longer presents minimal credit risk or is in default, the Portfolio
will dispose of the security as soon as reasonably practicable unless the Board
of Directors determines that it is not in the best interests of the Portfolio to
do so. The credit quality of municipal obligations is frequently enhanced by
various arrangements with domestic or foreign financial institutions, such as
letters of credit, guarantees and insurance, and these arrangements are
considered when investment quality is evaluated.
 
    PUTS FOR THE MUNICIPAL MONEY MARKET PORTFOLIO.  The Portfolio may to the
extent consistent with the Portfolio's investment policies, purchase without
limit municipal bonds or notes together with the right to resell them at an
agreed price or yield within a specified period prior to maturity. This right to
resell is known as a "put." The aggregate price paid for securities with puts
may be higher than the price which otherwise would be paid. The purpose of this
practice is to permit the Portfolio to be fully invested in tax-exempt
securities while maintaining the necessary liquidity to purchase securities on a
when-issued basis, to meet unusually large redemptions, to purchase at a later
date securities other than those subject to the put and to facilitate the
Adviser's ability to manage the Portfolio actively. The principal risk of puts
is that the put writer may default on its obligation to repurchase. The Adviser
will monitor each put writer's ability to meet its obligations. No value is
assigned to any puts. The cost of any such put is carried as an unrealized loss
from the time of purchase until it is exercised or expires.
 
                       ADDITIONAL INVESTMENT INFORMATION
 
    FOREIGN INVESTMENT.  The Fixed Income Portfolio may invest in U.S.
dollar-denominated securities of foreign issuers trading in U.S. markets and in
non-U.S. dollar-denominated obligations of foreign issuers. The Money Market
Portfolio may invest in U.S. dollar-denominated commercial paper issued by a
foreign corporation that is a direct parent or subsidiary of a U.S. corporation.
Investment in obligations of foreign issuers and in foreign branches of domestic
banks involves somewhat different investment risks than those affecting
obligations of U.S. issuers. There may be limited publicly available information
with respect to foreign issuers, and foreign issuers are not generally subject
to uniform accounting, auditing and financial standards and requirements
comparable to those applicable to domestic companies. Brokerage commissions and
other transaction costs on foreign securities exchanges are generally higher
than in the United States. Dividends and interest paid by foreign issuers may be
subject to withholding and other foreign taxes, which may decrease the net
return on foreign investments as compared to dividends and interest paid to the
Portfolio by domestic companies. It is not expected that a Portfolio or its
shareholders would be able to claim a credit for U.S. tax purposes with respect
to any such foreign taxes. Additional risks include future political and
economic developments, the possibility that a foreign jurisdiction might impose
or change withholding taxes on income payable with respect to foreign
securities, possible seizure, nationalization or expropriation of the foreign
issuer or foreign deposits, and the possible adoption of foreign governmental
restrictions such as exchange controls. Many of the foreign countries described
above may have less stable political environments than more developed countries.
Also, it may be more difficult to obtain a judgment in a court outside the
United States.
 
                                       18
<PAGE>
    Investments in securities of foreign issuers are frequently denominated in
foreign currencies and the Fixed Income Portfolio may temporarily hold
uninvested reserves in bank deposits in foreign currencies. Therefore, the value
of the Portfolio's assets as measured in U.S. dollars may be affected favorably
or unfavorably by changes in currency rates and in exchange control regulations,
and the Portfolio may incur costs in connection with conversions between various
currencies.
 
   
    FOREIGN CURRENCY FORWARD CONTRACTS.  The Fixed Income Portfolio may enter
into foreign currency forward contracts ("forward contracts") that provide for
the purchase or sale of an amount of a specified currency at a future date. The
Portfolio may use such contracts to protect against a decline in a foreign
currency against the U.S. dollar between the trade date and settlement date when
the Portfolio purchases or sells securities, lock in the U.S. dollar value of
dividends and interest on securities held by the Portfolio, and generally to
protect the U.S. dollar value of securities held by the Portfolio against
exchange rate fluctuation. While forward contracts may limit losses as a result
of exchange rate fluctuations, they will also limit any gains that might
otherwise have been realized. The Portfolio's Custodian may be required to place
cash or liquid securities in a segregated account in an amount equal to the
value of the Portfolio's total assets committed to the consummation of forward
contracts. If the value of the securities placed in the segregated account
declines, additional cash or securities will be placed in the account on a daily
basis so that the value of the account will be at least equal to the amount of
the Portfolio's commitments with respect to such contracts.
    
 
   
    FUTURES CONTRACTS AND OPTIONS ON FUTURES CONTRACTS.  Each Portfolio, except
the Money Market and Municipal Money Market Portfolios, may purchase and sell
futures contracts and options on futures contracts, including but not limited to
financial futures, securities index futures, foreign currency exchange futures,
and interest rate futures contracts. Futures contracts provide for the sale by
one party and purchase by another party of a specified amount of a specific
security, instrument or basket thereof, at a specific future date and at a
specified price. An option on a futures contract is a legal contract that gives
the holder the right to buy or sell a specified amount of futures contracts at a
fixed or determinable price upon the exercise of the option.
    
 
   
    The Portfolios may sell securities index futures contracts and/or options
thereon in anticipation of or during a market decline to attempt to offset the
decrease in market value of investments in its portfolio, or purchase securities
index futures in order to gain market exposure. Subject to applicable laws, the
Portfolios may engage in transactions in securities index futures contracts (and
options thereon) which are traded on a recognized securities or futures
exchange, or may purchase or sell such instruments in the over-the-counter
market. There currently are limited securities index futures and options on such
futures in many countries, particularly emerging countries. The nature of the
strategies adopted by the Adviser, and the extent to which those strategies are
used, may depend on the development of such markets.
    
 
   
    The Portfolios may engage in transactions involving foreign currency
exchange futures contracts. Such contracts involve an obligation to purchase or
sell a specific currency at a specified date and at a specified price. The
Portfolios may engage in such transactions to hedge their respective holdings
and commitments against changes in the level of future currency rates or to gain
exposure to a particular currency.
    
 
   
    The Portfolios may engage in transactions in interest rate futures
transactions. Interest rate futures contracts involve an obligation to purchase
or sell a specific debt security, instrument or basket thereof at a
    
 
                                       19
<PAGE>
   
specified future date at a specified price. The value of the contract rises and
falls inversely with changes in interest rates. The Portfolios may engage in
such transactions to hedge their holdings of debt instruments against future
changes in interest rates.
    
 
   
    Financial futures are futures contracts relating to financial instruments,
such as U.S. Government securities, foreign currencies, and certificates of
deposit. Such contracts involve an obligation to purchase or sell a specific
security, instrument or basket thereof at a specified future date at a specified
price. Like interest rate futures contracts, the value of financial futures
contracts rises and falls inversely with changes in interest rates. The
Portfolios may engage in financial futures contracts for hedging and non-hedging
purposes.
    
 
   
    Under rules adopted by the Commodity Futures Trading Commission, each
Portfolio may enter into futures contracts and options thereon for both hedging
and non-hedging purposes, provided that not more than 5% of such Portfolios'
total assets at the time of entering the transaction are required as margin and
option premiums to secure obligations under such contracts relating to
activities that do not constitute "bona-fide" hedging. No Portfolio, except the
Fixed Income Portfolio, will enter into futures contracts to the extent that its
outstanding obligations to purchase securities under such contracts, in
combination with its outstanding obligations with respect to options
transactions (including options to purchase securities or instruments) would
exceed 20% of its total assets.
    
 
   
    Gains and losses on futures contracts and options thereon depend on the
Adviser's ability to predict correctly the direction of securities prices,
interest rates and other economic factors. Other risks associated with the use
of futures and options are (i) imperfect correlation between the change in
market value of investments held by a Portfolio and the prices of futures and
options relating to investments purchased or sold by the Portfolio, and (ii)
possible lack of a liquid secondary market for a futures contract and the
resulting inability to close a futures position. The risk that a Portfolio will
be unable to close out a futures position or options contract will be minimized
by only entering into futures contracts or options transactions for which there
appears to be a liquid exchange or secondary market. The risk of loss in trading
on futures contracts in some strategies can be substantial, due both to the low
margin deposits required and the extremely high degree of leverage involved in
futures pricing.
    
 
    LOANS OF PORTFOLIO SECURITIES.  Each Portfolio may lend its securities to
brokers, dealers, domestic and foreign banks or other financial institutions for
the purpose of increasing its net investment income. These loans must be secured
continuously by cash or equivalent collateral or by a letter of credit at least
equal to the market value of the securities loaned plus accrued interest or
income. There may be risks of delay in recovery of the securities or even loss
of rights in the collateral should the borrower of the securities fail
financially. A Portfolio will not enter into securities loan transactions
exceeding, in the aggregate, 33 1/3% of the market value of the Portfolio's
total assets.
 
   
    MONEY MARKET INSTRUMENTS.  The Portfolios are permitted to invest in money
market instruments, although each Portfolio intends to stay invested in
securities satisfying its primary investment objective to the extent practical.
Each Portfolio may make money market investments pending other investment or
settlement for liquidity, or in adverse market conditions. See "Temporary
Investments." The money market investments permitted for the Portfolios include
obligations of the U.S. Government and its agencies and instrumentalities;
obligations of foreign sovereignties; other debt securities; commercial paper;
bank obligations; certificates of deposit (including Eurodollar certificates of
deposit); and repurchase agreements.
    
 
                                       20
<PAGE>
   
    OPTIONS TRANSACTIONS.  The Fixed Income Portfolio may seek to increase its
return or may hedge its portfolio investments through options transactions with
respect to securities, instruments, indices or baskets thereof in which the
Portfolio may invest, as well as with respect to foreign currency. Purchasing a
put option gives the Portfolio the right to sell a specified security, currency
or basket of securities or currencies at the exercise price until the expiration
of the option. Purchasing a call option gives the Portfolio the right to
purchase a specified security, currency or basket of securities or currencies at
the exercise price until the expiration of the option. The Portfolio may not
purchase call and put options to the extent that the value of its aggregate
investment in options exceeds 5% of its total assets.
    
 
   
    The Portfolio also may write (i.e., sell) put and call options on
investments held in its portfolio, as well as with respect to foreign currency.
A Portfolio that has written an option receives a premium, which increases the
Portfolio's return on the underlying security or instrument in the event the
option expires unexercised or is closed out at a profit. However, by writing a
call option, the Portfolio will limit its opportunity to profit from an increase
in the market value of the underlying security or instrument above the exercise
price of the option for as long as the Portfolio's obligation as writer of the
option continues. The Portfolio may only write options that are "covered." A
covered call option means that so long as the Portfolio is obligated as the
writer of the option, it will own (i) the underlying security or instrument
subject to the option or (ii) securities or instruments convertible or
exchangeable without the payment of any consideration into the security or
instrument subject to the option.
    
 
   
    By writing (or selling) a put option, the Portfolio incurs an obligation to
buy the security or instrument underlying the option from the purchaser of the
put at the option's exercise price at any time during the option period, at the
purchaser's election. Options written by the Portfolio may be exercisable by the
purchaser only on a specific date. A Portfolio that has written a put option
will earmark or segregate sufficient liquid assets to cover its obligations
under the option.
    
 
   
    The Portfolio may engage in transactions in options which are traded on
recognized exchanges or over-the-counter. There currently are limited options
markets in many countries, particularly emerging countries such as Latin
American countries, and the nature of the strategies adopted by the Adviser and
the extent to which those strategies are used will depend on the development of
such option markets. The primary risks associated with the use of options are
(i) imperfect correlation between the change in market value of investments
held, purchased or sold by the Portfolio and the prices of options relating to
such investments; and (ii) possible lack of a liquid secondary market for an
option.
    
 
    REPURCHASE AGREEMENTS.  Each Portfolio may enter into repurchase agreements
with brokers, dealers or banks that meet the credit guidelines of the Fund's
Board of Directors. In a repurchase agreement, a Portfolio buys a security from
a seller that has agreed to repurchase it at a mutually agreed upon date and
price, reflecting the interest rate effective for the term of the agreement. The
term of these agreements is usually from overnight to one week and never exceeds
one year. Repurchase agreements may be viewed as a fully collateralized loan of
money by the Portfolio to the seller. The Portfolio always receives securities
with a market value at least equal to the purchase price (including accrued
interest) as collateral, and this value is maintained during the term of the
agreement. If the seller defaults and the collateral value declines, the
Portfolio might incur a loss. If bankruptcy proceedings are commenced with
respect to the seller, the Portfolio's realization upon the collateral may be
delayed or limited. The Portfolio may not enter into repurchase agreements with
more than seven days to
 
                                       21
<PAGE>
maturity if, as a result, more than 15% of the market value of the Portfolio's
net assets are invested in these agreements and other investments for which
market quotations are not readily available or which are otherwise illiquid.
 
    REVERSE REPURCHASE AGREEMENTS.  The Money Market Portfolio may enter into
reverse repurchase agreements with brokers, dealers, domestic and foreign banks
or other financial institutions. In a reverse repurchase agreement, the
Portfolio sells a security and agrees to repurchase it at a mutually agreed upon
date and price, reflecting the interest rate effective for the term of the
agreement. Reverse Repurchase Agreements may also be viewed as the borrowing of
money by the Portfolio and are, therefore, subject to the Portfolio's overall
borrowing limitations. The Portfolio's investment of the proceeds of a reverse
repurchase agreement is the speculative factor known as leverage. The Portfolio
may enter into a reverse repurchase agreement only if the interest income from
investment of the proceeds is greater than the interest expense of the
transaction and the proceeds are invested for a period no longer than the term
of the agreement. The Portfolio will maintain with the Custodian a separate
account with a segregated portfolio of securities at least equal to its purchase
obligations under these agreements. If interest rates rise during a reverse
repurchase agreement, it may adversely affect the Portfolio's ability to
maintain a stable net asset value.
 
    TAXABLE INVESTMENTS.  The Municipal Bond and Municipal Money Market
Portfolios attempt to invest 80% and 100%, respectively, of their assets in
tax-exempt municipal securities. However, the Portfolios are permitted to invest
up to 20% of the value of their total assets in securities, the interest income
of which is subject to federal income tax. Either Portfolio may make taxable
investments pending investment of proceeds from sales of its shares or portfolio
securities or pending settlement of purchases of portfolio securities in order
to maintain liquidity to meet redemptions or when it is advisable in the
Adviser's opinion because of adverse market conditions. The taxable investments
permitted for either Portfolio include obligations of the U.S. Government and
its agencies and instrumentalities, bank obligations, commercial paper and
repurchase agreements. Fees from loans of tax-exempt securities will also be
taxable income of the Portfolio.
 
   
    TEMPORARY INVESTMENTS.  For temporary defensive purposes, when the Adviser
determines that market conditions warrant, each Portfolio may invest up to 100%
of its assets in dollar and non-dollar denominated money market instruments and
short- and medium-term debt securities that the Adviser believes to be of high
quality, or hold cash. The short- and medium-term debt securities in which a
Portfolio may invest consist of (a) obligations of the U.S. or foreign country
governments, their respective agencies or instrumentalities; (b) bank deposits
and bank obligations (including certificates of deposit, time deposits and
bankers' acceptances) of U.S. or foreign country banks denominated in any
currency; (c) floating rate securities and other instruments denominated in any
currency issued by international development agencies; (d) finance company and
corporate commercial paper and other short-term corporate debt obligations of
U.S. and foreign country corporations meeting the Portfolio's credit quality
standards; and (e) repurchase agreements with banks and broker-dealers with
respect to such securities.
    
 
    WHEN-ISSUED AND DELAYED DELIVERY SECURITIES.  Each Portfolio may purchase
securities on a when-issued or delayed delivery basis. In such transactions,
instruments are bought with payment and delivery taking place in the future in
order to secure what is considered to be an advantageous yield or price at the
time of the transaction. Delivery of and payment for these securities may take
as long as a month or more after the date of the purchase commitment but will
take place no more than 120 days after the trade date. Each Portfolio will
maintain with the Custodian a separate account with a segregated portfolio of
cash or liquid securities in an
 
                                       22
<PAGE>
amount at least equal to these commitments. The payment obligation and the
interest rates that will be received are each fixed at the time a Portfolio
enters into the commitment and no interest accrues to the Portfolio until
settlement. Thus, it is possible that the market value at the time of settlement
could be higher or lower than the purchase price if the general level of
interest rates has changed. It is a fundamental policy of the Money Market
Portfolio and a current policy of the Municipal Money Market Portfolio not to
enter into when-issued commitments exceeding, in the aggregate, 15% of the
market value of the Portfolio's total assets less liabilities other than the
obligations created by these commitments.
 
                             INVESTMENT LIMITATIONS
 
    Each Portfolio is a diversified investment company under the Investment
Company Act of 1940, as amended (the "1940 Act") and is subject to the following
limitations: (a) as to 75% of its total assets, a Portfolio may not invest more
than 5% of its total assets in the securities of any one issuer, except
obligations of the U.S. Government and its agencies and instrumentalities, and
(b) a Portfolio may not own more than 10% of the outstanding voting securities
of any one issuer.
 
    Each Portfolio also operates under certain investment restrictions that are
deemed fundamental limitations and may be changed only with the approval of the
holders of a majority of such Portfolio's outstanding shares and under certain
non-fundamental investment limitations that may be changed without shareholder
approval. For additional information on fundamental and non-fundamental
investment limitations, see "Investment Limitations" in the Statement of
Additional Information.
 
                             MANAGEMENT OF THE FUND
 
   
    INVESTMENT ADVISER.  Morgan Stanley Asset Management Inc. is the Adviser and
Administrator of the Fund and each portfolio. The Adviser provides investment
advice and portfolio management services pursuant to an Investment Advisory
Agreement and, subject to the supervision of the Fund's Board of Directors,
makes the portfolio's day-to-day investment decisions, arranges for the
execution of portfolio transactions and generally manages the portfolio's
investments. Set forth below as an annual percentage of daily net assets are the
management fees payable to the Adviser quarterly by each Portfolio pursuant to
the terms of the Investment Advisory Agreement. The Adviser has agreed to a
reduction in the fees payable to it and to reimburse the Non-Money Portfolios,
if necessary, if such fees would cause the total annual operating expenses of
any Portfolio to exceed the maximum set forth in the table below.
    
 
   
<TABLE>
<CAPTION>
                                                                       MAXIMUM TOTAL OPERATING EXPENSES
                                                                              AFTER FEE WAIVERS
                                                MANAGEMENT FEE     ----------------------------------------
PORTFOLIO                                     ABSENT FEE WAIVERS         CLASS A              CLASS B
- --------------------------------------------  -------------------  -------------------  -------------------
<S>                                           <C>                  <C>                  <C>
Fixed Income                                           0.35%                0.45%                0.60%
Municipal Bond                                         0.35%                0.45%                0.70%
Mortgage-Backed Securities                             0.35%                0.45%                0.70%
Money Market                                           0.30%                0.55%               N/A
Municipal Money Market                                 0.30%                0.57%               N/A
</TABLE>
    
 
   
    The Adviser, with principal offices at 1221 Avenue of the Americas, New
York, New York 10020, conducts a worldwide portfolio management business,
providing a broad range of portfolio management services to customers in the
U.S. and abroad. On February 5, 1997, Morgan Stanley Group Inc. and Dean Witter,
    
 
                                       23
<PAGE>
   
Non-Money Discover & Co. announced that they had entered into an Agreement and
Plan of Merger to form Morgan Stanley, Dean Witter, Discover & Co. Morgan
Stanley Group Inc. is the direct parent of the Adviser and Morgan Stanley.
Subject to certain conditions being met, it is currently anticipated that the
transaction will close in mid-1997. Thereafter, the Adviser and Morgan Stanley
will be subsidiaries of Morgan Stanley, Dean Witter, Discover & Co. At March 31,
1997, the Adviser, together with its affiliated asset management companies,
managed investments totaling in excess of $118 billion, including approximately
$100 billion under active management and $18 billion as Named Fiduciary or
Fiduciary Adviser. See "Management of the Fund" in the Statement of Additional
Information.
    
 
    PORTFOLIO MANAGERS.  The following individuals have primary portfolio
management responsibility for the Portfolios noted below:
 
    FIXED INCOME PORTFOLIO  --  WARREN ACKERMAN, III. Warren Ackerman is a
Principal of the Advisor and a Senior Fixed Income Portfolio Manager. Mr.
Ackerman joined the Advisor in December 1993. Prior to joining the Advisor, Mr.
Ackerman spent over 14 years with Bankers Trust Company as a Managing Director
responsible for institutional active fixed income management. Prior to Bankers,
he spent almost seven years as a Vice President with Irving Trust Company in the
Trust Investment Division. Mr. Ackerman is a graduate of Monmouth College with a
B.S. in Economics. Mr. Ackerman has had primary responsibility for managing the
Portfolio's assets since March 1994.
 
    MUNICIPAL BOND PORTFOLIO  --  LORI A. COHANE. Lori A. Cohane joined the
Adviser in 1994 as a Vice President and Municipal Bond Portfolio Manager. Prior
to joining the Adviser, Ms. Cohane spent eight years with Salomon Brothers Asset
Management as a Vice President, Portfolio Manager and Senior Credit Analyst of
municipal bond accounts managing portfolios for high net worth individuals,
open- and closed-end bond funds and institutional accounts. Ms. Cohane is a
magna cum laude graduate of the State University of New York at Albany with a
B.S. degree in Finance and Economics. Ms. Cohane has had primary responsibility
for managing the Portfolio's assets since its inception.
 
    MORTGAGE-BACKED SECURITIES PORTFOLIO  --  WARREN ACKERMAN, III. Information
about Mr. Ackerman is included under Fixed Income Portfolio above. Mr. Ackerman
has had primary responsibility for managing the Portfolio's assets since its
inception.
 
    MONEY MARKET PORTFOLIO  --  ABIGAIL JONES FEDER, KENNETH R. HOLLEY, ELLEN D.
HARVEY, CHRISTIAN G. ROTH AND SCOTT F. RICHARD. Abigail Feder is a Principal of
Morgan Stanley and shares responsibility for managing short-term taxable and
tax-exempt portfolios. Ms. Feder joined Morgan Stanley's Corporate Finance
Department in 1985. In 1987 she joined the Adviser as a Marketing Analyst and
was promoted to a Marketing Director in 1988. She joined the Fixed Income Group
as a Portfolio Manager in 1989 and she became a Vice President in 1992. Ms.
Feder holds a B.A. from Vassar College. Kenneth R. Holley joined the Adviser as
a short-term fixed income portfolio manager in July, 1993. Prior thereto, he
worked for 2 1/2 years as a Finance Officer for the African Development Bank
implementing trading strategies for the bank's $1 billion short to intermediate
U.S. dollar portfolio. Prior to joining the ADB, Mr. Holley spent 1 1/2 years
with Ward and Associates Asset Management as a Vice President responsible for
fixed income strategy. Before Ward and Associates he worked in the fixed income
department of Salomon Brothers, Inc. Mr. Holley holds a B.S. degree in
Engineering from University of Pennsylvania and an M.B.A. from the Wharton
School. Mr. Barth and Ms. Feder have had primary responsibility for managing the
Portfolio's assets since inception. Mr. Holley has shared primary responsibility
for managing
 
                                       24
<PAGE>
   
the Portfolio's assets since August, 1993. Ellen D. Harvey shares primary
responsibility for managing the Portfolio's assets. She joined the Adviser in
1996 and has been a portfolio manager with Miller Anderson & Sherrerd, LLP
("MAS"), an affiliate of the Adviser, since 1984. She assumed responsibility for
the MAS-advised Cash Reserves Portfolio in 1990, the Limited Duration Portfolio
in 1992 and the Intermediate Duration Portfolio in 1994. Ms. Harvey holds an
A.B. in economics from Princeton University and an M.A. in economics from George
Washington University. Christian G. Roth shares primary responsibility for
managing the Portfolio's assets. He joined the Adviser in 1996 and has been a
portfolio manager with MAS since 1991. He served as Senior Associate, Dean
Witter Capital Corporation from 1987 to 1991. He assumed responsibility for the
MAS-advised Limited Duration and Intermediate Duration Portfolios in 1994. Mr.
Roth holds a B.S. from The Wharton School of the University of Pennsylvania.
Scott F. Richard shares primary responsibility for managing the Portfolio's
assets. He joined the Adviser in 1996 and has been a portfolio manager with MAS
since 1992. He served as Vice President, Head of Fixed Income Research & Model
Development for Goldman, Sachs & Co. from 1987 to 1991 and as Head of Mortgage
Research in 1992. He assumed responsibility for the MAS-advised Mortgage-Backed
Securities Portfolio in 1992 and the Limited Duration, Intermediate Duration,
Municipal and PA Municipal Portfolios in 1994. Mr. Richard holds a B.S. from
Massachusetts Institute of Technology and a D.B.A. from Harvard Graduate School
of Business Administration.
    
 
    MUNICIPAL MONEY MARKET PORTFOLIO  --  GERALD P. BARTH AND ABIGAIL JONES
FEDER. Information about Mr. Barth and Ms. Feder is included under Money Market
Bond Portfolio above. Mr. Barth and Ms. Feder have shared primary responsibility
for managing the Portfolio's assets since inception.
 
    ADMINISTRATOR.  The Adviser also provides administrative services to the
Fund pursuant to an Administration Agreement. The services provided under the
Administration Agreement are subject to the supervision of the Officers and the
Board of Directors of the Fund, and include day-to-day administration of matters
related to the corporate existence of the Fund, maintenance of its records,
preparation of reports, supervision of the Fund's arrangements with its
custodian and assistance in the preparation of the Fund's registration
statements under federal laws. The Administration Agreement also provides that
the Administrator through its agents will provide dividend disbursing and
transfer agent services to the Fund. For its services under the Administration
Agreement, the Fund pays the Adviser a monthly fee which on an annual basis
equals .15% of the average daily net assets of each Portfolio.
 
   
    Under an agreement between the Adviser and The Chase Manhattan Bank
("Chase"), Chase provides certain administrative services to the Fund through
its corporate affiliate, Chase Global Funds Services Company ("CGFSC"). The
Adviser supervises and monitors such administrative services provided by CGFSC.
Their services are also subject to the supervision of the Board of Directors of
the Fund. CGFSC's business address is 73 Tremont Street, Boston, Massachusetts
02108-3913.
    
 
    DIRECTORS AND OFFICERS.  Pursuant to the Fund's Articles of Incorporation,
the Board of Directors decides upon matters of general policy and reviews the
actions of the Fund's Adviser, Administrator, Distributor and other service
providers. The Officers of the Fund conduct and supervise its daily business
operations.
 
    DISTRIBUTOR.  Morgan Stanley serves as the exclusive Distributor of the
shares of the Fund. Under its Distribution Agreement with the Fund, Morgan
Stanley sells shares of each Portfolio upon the terms and at the current
offering price described in this Prospectus. Morgan Stanley is not obligated to
sell any certain number of shares of any Portfolio.
 
                                       25
<PAGE>
    The Portfolios currently offer only the classes of shares offered by this
Prospectus. The Portfolios may in the future offer one or more classes of shares
with features, distribution expenses or other expenses that are different from
those of the classes currently offered.
 
   
    The Fund has adopted a Plan of Distribution with respect to the Class B
shares of each of the Non-Money Portfolios pursuant to Rule 12b-1 under the 1940
Act (each, a "Plan"). Under each Plan, the Distributor is entitled to receive
from each of the Non-Money Portfolios a distribution fee, which is accrued daily
and paid quarterly, of 0.25% of the Class B shares' average daily net assets on
an annualized basis. The Distributor expects to reallocate most of its fee to
its investment representatives. The Distributor may, in its discretion,
voluntarily waive from time to time all or any portion of its distribution fee
and each of the Distributor and the Adviser is free to make additional payments
out of its own assets to promote the sale of Fund shares, including payments
that compensate financial institutions for distribution services or shareholder
services. The Distributor has agreed to waive 0.10% of the 0.25% distribution
fee it is entitled to receive from the Fixed Income Portfolio.
    
 
    Each Plan is designed to compensate the Distributor for its services, not to
reimburse the Distributor for its expenses, and the Distributor may retain any
portion of the fee that it does not expend in fulfillment of its obligations to
the Fund.
 
    EXPENSES.  Each Portfolio is responsible for payment of certain other fees
and expenses (including legal fees, accountant's fees, custodial fees and
printing and mailing costs) specified in the Administration and Distribution
Agreements.
 
                               PURCHASE OF SHARES
 
    Class A and Class B shares of the Non-Money Portfolios and Class A shares of
the Money Portfolios may be purchased, without sales commission, at the net
asset value per share next determined after receipt of the purchase order by the
Non-Money Portfolio and, in the case of the Money Portfolios, at the price next
determined after Federal Funds are available to the Money Portfolio. See
"Valuation of Shares."
 
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
 
    For a Non-Money Portfolio account opened on or after January 2, 1996 (a "New
Non-Money Account"), the minimum initial investment and minimum account size are
$500,000 for Class A shares and $100,000 for Class B shares. The minimum initial
investment for each Money Portfolio is $50,000. Certain advisory or asset
allocation accounts, such as Total Funds Management accounts, managed by Morgan
Stanley or its affiliates, including the Adviser ("Managed Accounts") may
purchase Class A shares without being subject to any minimum initial investment
or minimum account size requirements for a Portfolio account. Employees of the
Adviser and certain of its affiliates may purchase Class A shares subject to
conditions, including a lower minimum initial investment, established by
Officers of the Fund.
 
    If the value of a New Non-Money Account containing Class A shares falls
below $500,000 (but remains at or above $100,000) because of shareholder
redemption(s), the Fund will notify the shareholder, and if the account value
remains below $500,000 (but remains at or above $100,000) for a continuous
60-day period, the Class A shares in such account will convert to Class B shares
and will be subject to the distribution fee and other features
 
                                       26
<PAGE>
applicable to the Class B shares. The Fund, however, will not convert Class A
shares to Class B shares based solely upon changes in the market that reduce the
net asset value of shares. Under current tax law, conversions between share
classes are not a taxable event to the shareholder.
 
    Shares in a Portfolio account opened prior to January 2, 1996 were
designated Class A shares on January 2, 1996. Shares in a Non-Money Portfolio
account opened prior to January 2, 1996 (each, a "Pre 1996 Non-Money Account")
with a value of $100,000 or more on March 1, 1996 (a "Grandfathered Class A
Account") remained Class A shares regardless of account size thereafter. Except
for shares in a Managed Account, shares in a Pre-1996 Non-Money Account with a
value of less than $100,000 on March 1, 1996 (a "Grandfathered Class B Account")
convert to Class B shares on March 1, 1996. Grandfathered Class A Accounts and
Managed Accounts are not subject to conversion from Class A shares to Class B
shares.
 
    Investors may also invest in the Fund by purchasing shares through a trust
department, broker, dealer, agent, financial planner, financial services firm or
investment adviser. An investor may be charged an additional service or
transaction fee by that institution.
 
   
    The minimum investment levels may be waived at the discretion of the Adviser
for (i) certain employees and customers of Morgan Stanley or its affiliates and
certain trust departments, brokers, dealers, agents, financial planners,
financial services firms, or investment advisers that have entered into an
agreement with Morgan Stanley or its affiliates; and (ii) retirement and
deferred compensation plans and trusts used to fund such plans, including, but
not limited to, those defined in Section 401(a), 403(b) or 457 of the Internal
Revenue Code of 1986, as amended (the "Code") and "rabbi trusts". The Fund
reserves the right to modify or terminate the conversion features of the shares
as stated above at any time upon 60-days notice to shareholders.
    
 
    The Adviser reserves the right in its sole discretion to determine which of
such advisory or asset allocation accounts shall be Managed Accounts. For
information regarding Managed Accounts, please contact your Morgan Stanley
account representative or the Fund at the telephone number provided on the cover
of this Prospectus.
 
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
 
   
    If the value of a New Non-Money Account falls below $100,000 because of
shareholder redemption(s), the Fund will notify the shareholder, and if the
account value remains below $100,000 for a continuous 60-day period, the shares
in such accounts are subject to redemption by the Fund and, if redeemed, the net
asset value of such shares will be promptly paid to the shareholder. The Fund,
however, will not redeem shares based solely upon changes in the market that
reduce the net asset value of shares.
    
 
   
    Grandfathered Class A Accounts, Grandfathered Class B Accounts and Managed
Accounts are not subject to involuntary redemption. If a shareholder reduces its
total investment in Class A shares of a Money Portfolio to less than $10,000,
the investment may be subject to redemption. The Fund reserves the right to
modify or terminate the involuntary redemption features of the shares as stated
above at any time upon 60-days notice to shareholders.
    
 
CONVERSION FROM CLASS B TO CLASS A SHARES
 
    If the value of Class B shares in a Non-Money Portfolio account increases,
whether due to shareholder share purchases or market activity, to $500,000 or
more, the Class B shares will convert to Class A shares. Under current tax law,
such conversion is not a taxable event to the shareholder. Class A shares
converted from Class B
 
                                       27
<PAGE>
   
shares are subject to the same minimum account size requirements that are
applicable to New Non-Money Accounts containing Class A shares, as stated above.
The Fund reserves the right to modify or terminate this conversion feature at
any time upon 60-days notice to shareholders.
    
 
INITIAL PURCHASES DIRECTLY FROM THE FUND
 
    The Fund's determination of an investor's eligibility to purchase shares of
a given class will take precedence over the investor's selection of a class.
Assuming the investor is eligible for the class, the Fund will select the most
favorable class for the investor, if the investor has not done so.
 
1) BY CHECK.  An account may be opened by completing and signing an Account
   Registration Form and mailing it, together with a check ($500,000 minimum for
   Class A shares of each Non-Money Portfolio, $100,000 minimum for Class B
   shares of each Non-Money Portfolio, and $50,000 minimum for each Money
   Portfolio, with certain exceptions for Morgan Stanley employees and select
   customers, including those who participate in the Automatic Purchase of
   Portfolio Shares program described below) payable to "Morgan Stanley
   Institutional Fund, Inc. -- [portfolio name]", to:
 
      Morgan Stanley Institutional Fund, Inc.
      P.O. Box 2798
      Boston, Massachusetts 02208-2798
 
    Payment will be accepted only in U.S. dollars, unless prior approval for
  payment by other currencies is given by the Fund. The classes of shares of the
  Portfolio(s) to be purchased should be designated on the Account Registration
  Form. For purchases by check, the Fund is ordinarily credited with Federal
  Funds within one business day. Thus, your purchase of shares by check is
  ordinarily credited to your account at the net asset value per share of the
  relevant Portfolio determined on the next business day after receipt.
 
2) BY FEDERAL FUNDS WIRE.  Purchases may be made by having your bank wire
   Federal Funds to the Fund's bank account. In order to ensure prompt receipt
   of your Federal Funds Wire, it is important that you follow these steps:
 
A.  Telephone the Fund (toll free: 1-800-548-7786) and provide us with your
    name, address, telephone number, Social Security or Tax Identification
    Number, the portfolio(s) selected, the class selected, the amount being
    wired, and by which bank. We will then provide you with a Fund account
    number. (Investors with existing accounts should also notify the Fund prior
    to wiring funds.)
 
B.  Instruct your bank to wire the specified amount to the Fund's Wire
    Concentration Bank Account (be sure to have your bank include the name of
    the portfolio(s) selected, the class selected and the account number
    assigned to you) as follows:
 
   
    The Chase Manhattan Bank
    One Manhattan Plaza
    New York, NY 10081-1000
    ABA#021000021
    DDA#910-2-733293
    Attn: Morgan Stanley Institutional Fund, Inc.
    Ref: (Portfolio name, your account number, your account name)
    
 
                                       28
<PAGE>
    Please call the Fund at 1-800-548-7786 prior to wiring funds.
 
C.  Complete and sign the Account Registration Form and mail it to the address
    shown thereon.
 
  The purchase price of the Class A and Class B shares of each Non-Money
  Portfolio is the net asset value next determined after the order is received.
  See "Valuation of Shares." An order received prior to the regular close of the
  New York Stock Exchange ("NYSE"), which is currently 4:00 p.m. Eastern Time,
  will be executed at the price computed on the date of receipt; an order
  received after the regular close of the NYSE will be executed at the price
  computed the next day the NYSE is open as long as the Transfer Agent receives
  payment by check or in Federal Funds prior to the regular close of the NYSE on
  such day. Orders for the purchase of shares of the Money Market Portfolio or
  Municipal Money Market Portfolio become effective on the business day Federal
  Funds are received, and the purchase will be effected at the net asset value
  next computed after receipt.
 
  Federal Funds purchase orders will be accepted only on a day on which the Fund
  and Chase (the "Custodian Bank") are open for business. Share purchases of the
  Money Market Portfolio in Federal Funds received by 12:00 noon (Eastern Time),
  and share purchases of the Municipal Money Market Portfolio in Federal Funds
  received by 11:00 a.m. (Eastern Time) will begin to earn income on the day of
  receipt. Your bank may charge a service fee for wiring Federal Funds.
 
3) BY BANK WIRE.  The same procedure outlined under "By Federal Funds Wire"
   above must be followed in purchasing shares by bank wire. However, money
   transferred by bank wire may or may not be converted into Federal Funds the
   same day, depending on the time the money is received and the bank handling
   the wire. Prior to such conversion, an investor's money will not be invested.
   For the Money Market and Municipal Money Market Portfolios, if money is not
   converted the same day, it will be converted the next business day and shares
   will be purchased at the net asset value next determined after such
   conversion. Your bank may charge a service fee for wiring funds.
 
4) AUTOMATIC PURCHASE OF PORTFOLIO SHARES.  Free cash balances (i.e., any cash
   that is available on demand at the close of the previous business day) which
   are held in certain eligible accounts at Morgan Stanley Asset Management
   Inc., Morgan Stanley or any other affiliated investment adviser or broker,
   and which are selected at the discretion of the Adviser, will be
   automatically invested on the next business day at net asset value in shares
   of the Money Market Portfolio or the Municipal Money Market Portfolio. A
   shareholder may elect in writing from time to time in which portfolio to
   invest. This automatic purchase facility permits certain eligible investment
   management and brokerage customers of Morgan Stanley to have their free cash
   balances invested in portfolio shares on a daily basis pending other
   investments.
 
ADDITIONAL INVESTMENTS
 
   
    You may add to your account at any time (minimum additional investment
$1,000 for each portfolio, except for automatic reinvestment of dividends and
capital gains distributions for which there are no minimums) by purchasing
shares at net asset value by mailing a check to the Fund (payable to "Morgan
Stanley Institutional Fund, Inc. -- [portfolio name]") at the above address or
by wiring monies to the Custodian Bank as outlined above. It is very important
that your account name, the Portfolio name and the class selected be specified
in the letter or wire to assure proper crediting to your account. In order to
ensure that your wire orders are invested
    
 
                                       29
<PAGE>
promptly, you are requested to notify one of the Fund's representatives
(toll-free 1-800-548-7786) prior to the wire date. Additional investments will
be applied to purchase additional shares in the same class held by a shareholder
in a Portfolio account.
 
OTHER PURCHASE INFORMATION
 
    Although the legal rights of Class A and Class B shares will be identical,
the different expenses borne by each class will result in different net asset
values and dividends. The net asset value of Class B shares will generally be
lower than the net asset value of Class A shares as a result of the distribution
expense charged to Class B shares. It is expected, however, that the net asset
value per share of the two classes will tend to converge immediately after the
recording of dividends which will differ by approximately the amount of the
distribution expense accrual differential between the classes.
 
   
    In the interest of economy and convenience, and because of the operating
procedures of the Fund, certificates representing shares of the Portfolios will
not be issued. All shares purchased are confirmed to you and credited to your
account on the Fund's books maintained by the Adviser or its agents. You will
have the same rights and ownership with respect to such shares as if
certificates had been issued.
    
 
    To ensure that checks are collected by the Fund, withdrawals of investments
made by check are not presently permitted until payment for the purchase has
been received, which may take up to eight business days after the date of
purchase. As a condition of this offering, if a purchase is cancelled due to
nonpayment or because your check does not clear, you will be responsible for any
loss the Fund or its agents incur. If you are already a shareholder, the Fund
may redeem shares from your account(s) to reimburse the Fund or its agents for
any loss. In addition, you may be prohibited or restricted from making future
investments in the Fund.
 
    Investors may also invest in the Fund by purchasing shares through the
Distributor.
 
EXCESSIVE TRADING
 
   
    Frequent trades involving either substantial portfolio assets or a
substantial portion of your account or accounts controlled by you can disrupt
management of a Portfolio and raise its expenses. Consequently, in the interest
of all the stockholders of the Portfolios and each Portfolio's performance, the
Fund may in its discretion bar a stockholder that engages in excessive trading
of shares of any class of a portfolio from further purchases of shares of the
Fund for an indefinite period. The Fund considers excessive trading to be more
than one purchase and sale involving shares of the same class of a portfolio of
the Fund within any 120-day period. As an example, exchanging shares of
portfolios of the Fund as follows amounts to excessive trading: exchanging
shares of Portfolio A for shares of Portfolio B, then exchanging shares of
Portfolio B for shares of Portfolio C and again exchanging shares of Portfolio C
for shares of Portfolio B within a 120-day period. Two types of transactions are
exempt from these excessive trading restrictions: (1) trades exclusively between
money market portfolios; and (2) trades done in connection with an asset
allocation service, such as TFM Accounts or accounts, managed or advised by the
Adviser and/or any of its affiliates.
    
 
INVESTMENT IN FUNDS THROUGH A TOTAL FUNDS MANAGEMENT ("TFM") ACCOUNT
 
   
    In addition to the considerable diversification among individual securities
you receive by investing in a particular Portfolio, you can further reduce risk
by spreading your assets among several different Portfolios that each have
different risk and return characteristics. TFM is an active investment
management service managed by Morgan Stanley or its affiliates, including Morgan
Stanley Asset Management Inc. (each, a "TFM Adviser"),
    
 
                                       30
<PAGE>
   
that allocates your investments across a combination of either Class A or Class
B shares of certain of the Portfolios selected to meet your long-term investment
objectives as well as, in certain circumstances, your current income objectives.
    
 
   
    The TFM Adviser has developed investment strategies for TFM Accounts to meet
the diverse financial needs of different investors. You can open a TFM Account
by meeting with one of the investment professionals of a Participating Dealer
who will review your situation and help you identify your long-term investment
and/or current income objectives. After using TFM criteria to determine your
long-term investment and/or current income objectives, you can choose one of
several TFM investment strategies. Based on your chosen strategy, your initial
investment will be allocated among a number of the Class A or Class B shares of
the Portfolios. Depending on market conditions, the TFM Adviser periodically
reallocates the combination of Portfolios or the percentage amounts invested in
the shares of each Portfolio to implement your TFM investment strategy. In
addition, your TFM Account will be periodically rebalanced to maintain your TFM
strategy's current asset allocation mix, if and when the performance of one or
more of the Portfolios unbalances the strategy's mix. You will pay the TFM
Adviser a fee for the TFM Account service that is in addition to and separate
from the fees and expenses you will pay directly or indirectly as an investor in
the Portfolios. See "Fund Expenses."
    
 
   
    From time to time, one or more of the Portfolios used for investment by the
TFM Accounts may experience relatively large investments or redemptions due to
the TFM Account allocations or rebalancings recommended by the TFM Adviser.
These transactions will affect the Portfolios, since Portfolios that experience
redemptions as a result of reallocations or rebalancings may have to sell
portfolio securities and Portfolios that receive additional cash will have to
invest it in additional portfolio securities. While it is impossible to predict
the overall impact of these transactions over time, there could be adverse
effects on portfolio management to the extent that Portfolios may be required to
sell securities or invest cash at times when they would not otherwise do so.
These transactions could also have tax consequences if sales of securities
resulted in gains and could also increase transaction costs. The Adviser,
representing the interests of the Portfolios, is committed to minimizing the
impact of TFM Account transactions on the Portfolios. The Adviser, however, will
have a conflict in fulfilling this responsibility in that it also serves as a
TFM Adviser. In that capacity, the Adviser, representing the interests of the
TFM Accounts, also is committed to minimizing the impact of TFM Account
transactions on the Portfolios to the extent consistent with pursuing the
investment objectives of the TFM Accounts. In addition, an affiliate of the TFM
Adviser, the Distributor is compensated on the sale, and may be compensated for
distribution or shareholder services on the sale of shares of the Portfolios.
See "Purchase of Shares" and "Shareholder Services -- Exchange Features." The
Adviser will monitor the impact of TFM Account transactions on the Portfolios.
    
 
                              REDEMPTION OF SHARES
 
    You may withdraw all or any portion of the amount in your account by
redeeming shares at any time. Please note that purchases made by check are not
permitted to be redeemed until payment of the purchase price has been collected,
which may take up to eight business days after purchase. The Fund will redeem
Class A and Class B shares of each Non-Money Portfolio and Class A shares of
each Money Portfolio at the next determined net asset value of shares of the
applicable class. On days that both the NYSE and the Custodian Bank are open for
business, the net asset value per share of the Fixed Income, Municipal Bond and
Mortgage-Backed Securities Portfolios is determined at the regular close of
trading of the NYSE (currently 4:00 p.m. Eastern
 
                                       31
<PAGE>
Time), and the net asset value per share of the Municipal Money Market Portfolio
is determined at 11:00 a.m. (Eastern Time) and the net asset value per share of
the Money Market Portfolio is determined at 12:00 p.m. (Eastern Time). Shares of
a Portfolio may be redeemed by mail or telephone. No charge is made for
redemption. Any redemption proceeds may be more or less than the purchase price
of your shares depending on, among other factors, the market value of the
investment securities held by the Portfolio.
 
BY MAIL
 
    Each Non-Money Portfolio will redeem its Class A and Class B shares and each
Money Portfolio will redeem its Class A shares at the net asset value next
determined after your request is received if the request is received in "good
order." Your request should be addressed to Morgan Stanley Institutional Fund,
Inc., P.O. Box 2798, Boston, Massachusetts 02208-2798, except that deliveries by
overnight courier should be addressed to Morgan Stanley Institutional Fund,
Inc., c/o Chase Global Funds Services Company, 73 Tremont Street, Boston,
Massachusetts 02108-3913.
 
    "Good order" means that the request to redeem shares must include the
following documentation:
 
        (a)  A letter of instruction or a stock assignment specifying the class
    and number of shares or dollar amount to be redeemed, signed by all
    registered owners of the shares in the exact names in which they are
    registered;
 
        (b) Any required signature guarantees (see "Further Redemption
    Information" below); and
 
        (c)  Other supporting legal documents, if required, in the case of
    estates, trusts, guardianships, custodianships, corporations, pension and
    profit-sharing plans and other organizations.
 
    Shareholders who are uncertain of requirements for redemption should consult
with a Fund representative.
 
BY TELEPHONE
 
    Provided you have previously elected the Telephone Redemption Option on the
Account Registration Form, you can request a redemption of your shares by
calling the Fund and requesting the redemption proceeds be mailed to you or
wired to your bank. Please contact one of Fund's representatives for further
details. In times of drastic market conditions, the telephone redemption option
may be difficult to implement. If you experience difficulty in making a
telephone redemption, your request may be made by mail or express mail and will
be implemented at the net asset value next determined after it is received.
Redemption requests sent to the Fund through express mail must be mailed to the
address of the Dividend Disbursing and Transfer Agent listed under "General
Information." The Fund and the Fund's transfer agent (the "Transfer Agent") will
employ reasonable procedures to confirm that the instructions communicated by
telephone are genuine. These procedures include requiring the investor to
provide certain personal identification information at the time an account is
opened and prior to effecting each transaction requested by telephone. In
addition, all telephone transaction requests will be recorded and investors may
be required to provide additional telecopied written instructions regarding
transaction requests. Neither the Fund nor the Transfer Agent will be
responsible for any loss, liability, cost or expense for following instructions
received by telephone that either of them reasonably believes to be genuine.
 
    To change the name of the commercial bank or account designated to receive
redemption proceeds, a written request must be sent to the Fund at the address
above. Requests to change the bank or account must be signed by each shareholder
and each signature must be guaranteed.
 
                                       32
<PAGE>
FURTHER REDEMPTION INFORMATION
 
    Normally the Fund will make payment for all shares redeemed within one
business day of receipt of the request, but in no event will payment be made
more than seven days after receipt of a redemption request in good order.
However, payments to investors redeeming shares which were purchased by check
will not be made until payment for the purchase has been collected, which may
take up to eight days after the date of purchase. The Fund may suspend the right
of redemption or postpone the date upon which redemptions are effected at times
when the NYSE is closed, or under any emergency circumstances as determined by
the Commission.
 
    If the Board of Directors determines that it would be detrimental to the
best interests of the remaining shareholders of a Portfolio to make payment
wholly or partly in cash, the Fund may pay the redemption proceeds in whole or
in part by a distribution-in-kind of securities held by a Portfolio in lieu of
cash in conformity with applicable rules of the Commission.
Distributions-in-kind will be made in readily marketable securities. Investors
may incur brokerage charges on the sale of Portfolio securities so received in
payment of redemptions.
 
    To protect your account, the Fund and its agents from fraud, signature
guarantees are required for certain redemptions to verify the identity of the
person who has authorized a redemption from your account. Please contact the
Fund for further information. See "Redemption of Shares" in the Statement of
Additional Information.
 
                              SHAREHOLDER SERVICES
 
EXCHANGE FEATURES
 
   
    You may exchange shares that you own in a Portfolio for shares of any other
available portfolio(s) of the Fund (other than the International Equity
Portfolio, which is closed to new investors). In exchanging for shares of a
portfolio with more than one class, the class of shares you receive in the
exchange will be determined in the same manner as any other purchase of shares
and will not be based on the class of shares surrendered for the exchange.
Consequently, the same minimum initial investment and minimum account size for
determining the class of shares received in the exchange will apply. See
"Purchase of Shares." Shares of the portfolios may be exchanged by mail or
telephone. The privilege to exchange shares by telephone is automatic and made
available without shareholder election. Before you make an exchange, you should
read the prospectus of the portfolio(s) in which you seek to invest. Because an
exchange transaction is treated as a redemption followed by a purchase, an
exchange would be considered a taxable event for shareholders subject to tax.
The exchange privilege may be modified or terminated by the Fund at any time
upon 60-days notice to shareholders.
    
 
BY MAIL
 
    In order to exchange shares by mail, you should include in the exchange
request the name, class of shares and account number of your current Portfolio,
the names of the portfolio(s) and class(es) of shares into which you intend to
exchange shares, and the signatures of all registered account holders. Send the
exchange request to Morgan Stanley Institutional Fund, Inc., P.O. Box 2798,
Boston, MA 02208-2798.
 
BY TELEPHONE
 
   
    When exchanging shares by telephone, have ready the name, class of shares
and account number of the current Portfolio, the name(s) of the portfolio(s) and
class(es) of shares into which you intend to exchange shares, your Social
Security number or Tax I.D. number, and your account address. Requests for
telephone exchanges
    
 
                                       33
<PAGE>
   
received prior to 4:00 p.m. (Eastern Time) are processed at the close of
business that same day based on the net asset value of the class of the
portfolios involved in the exchange of shares at the close of business. Requests
received after 4:00 p.m. are processed the next business day based on the net
asset value determined at the close of such day. For additional information
regarding responsibility for the authenticity of telephoned instructions, see
"Redemption of Shares -- By Telephone" above.
    
 
TRANSFER OF REGISTRATION
 
    You may transfer the registration of any of your Portfolio shares to another
person by writing to Morgan Stanley Institutional Fund, Inc., P.O. Box 2798,
Boston, Massachusetts 02208-2798. As in the case of redemptions, the written
request must be received in good order before any transfer can be made.
Transferring the registration of shares may affect the eligibility of your
account for a given class of the Portfolios' shares and may result in
involuntary conversion or redemption of your shares. See "Purchase of Shares"
above.
 
                              VALUATION OF SHARES
 
   
    The net asset value per share of a class of shares of each Non-Money
Portfolio is determined by dividing the total market value of the Non-Money
Portfolio's investments and other assets attributable to such class, less all
liabilities attributable to such class, by the number of total outstanding
shares of such a class of the Non-Money Portfolio. Net asset value is calculated
separately for each class of the Portfolio. Net asset value per share of the
Non-Money Portfolios is determined as of the regular close of the NYSE on each
day that the NYSE is open for business. Price information on listed securities
is taken from the exchange where the security is primarily traded. Securities
listed on a U.S. securities exchange for which market quotations are available
are valued at the last quoted sale price on the day the valuation is made.
Securities listed on a foreign exchange are valued at their closing price.
Unlisted securities and listed securities not traded on the valuation date for
which market quotations are readily available are valued at a price within a
range not exceeding the current asked price nor less than the current bid price.
The current bid and asked prices are determined based on the average of the bid
and asked prices quoted on such valuation date by two reputable brokers.
    
 
    Bonds and other fixed income securities are valued according to the broadest
and most representative market, which will ordinarily be the over-the-counter
market. Net asset value includes interest on fixed income securities, which is
accrued daily unless collection is in doubt. In addition, bonds and other fixed
income securities may be valued on the basis of prices provided by a pricing
service when such prices are believed to reflect the fair market value of such
securities. The prices provided by a pricing service are determined without
regard to bid or last sale prices, but take into account institutional size,
trading in similar groups of securities and any developments related to the
specific securities. Securities not priced in this manner are valued at the most
recently quoted bid price or, when securities exchange valuations are used, at
the latest quoted sale price on the day of valuation. If there is no such
reported sale, the latest quoted bid price will be used. Securities purchased
with remaining maturities of 60 days or less are valued at amortized cost, if it
approximates market value. In the event that amortized cost does not approximate
market value, market prices as determined above will be used.
 
   
    The value of other assets and securities for which quotations are not
readily available (including restricted and unlisted foreign securities) and
those securities for which it is inappropriate to determine prices in
    
 
                                       34
<PAGE>
   
accordance with the above-stated procedures are determined in good faith at fair
value using methods determined by the Board of Directors. For purposes of
calculating net asset value per share, all assets and liabilities initially
expressed in foreign currencies will be converted into U.S. dollars at the mean
of the bid and asked price for such currencies against the U.S. dollar last
quoted by any major bank.
    
 
    Although the legal rights of Class A and Class B shares will be identical,
the different expenses borne by each class will result in different net asset
values and dividends for the class. Dividends will differ by approximately the
amount of the distribution expense accrual differential among the classes. The
net asset value of Class B shares will generally be lower than the net asset
value of Class A shares as a result of the distribution expenses charged to
Class B shares.
 
   
    The net asset value per share of each of the Money Market and Municipal
Money Market Portfolios is determined by subtracting the Portfolio's liabilities
(including accrued expenses and dividends payable) from the total value of the
Portfolio's investments and other assets and dividing the result by the total
number of outstanding shares of the Portfolio. The net asset values per share of
the Municipal Money Market Portfolio and the Money Market Portfolio are
determined at 11:00 a.m. and 12:00 noon (Eastern Time), respectively, on the
days on which the NYSE is open. For the purpose of calculating each Money Market
Portfolio's net asset value per share, securities are valued by the "amortized
cost" method of valuation, which does not take into account unrealized gains or
losses. This involves valuing an instrument at its cost and thereafter assuming
a constant amortization to maturity of any discount or premium, regardless of
the impact of fluctuating interest rates on the market value of the instrument.
While this method provides certainty in valuation, it may result in periods
during which the value, as determined by amortized cost, is higher or lower than
the price the Portfolio would receive if it sold the instrument.
    
 
                            PERFORMANCE INFORMATION
 
    The Fund may from time to time advertise total return for each class of the
Fixed Income, Municipal Bond and Mortgage-Backed Securities Portfolios. In
addition, from time to time the Fund may advertise "yield" for the Municipal
Bond, Money Market and Municipal Money Market Portfolios and "effective yield"
for the Money Market and Municipal Money Market Portfolios. In addition to these
yield figures, the Municipal Bond and Municipal Money Market Portfolio may
advertise a tax equivalent yield. THESE FIGURES ARE BASED ON HISTORICAL
PERFORMANCE AND ARE NOT INTENDED TO INDICATE FUTURE PERFORMANCE.
 
    Each of the Non-money Portfolios may advertise "total return" which shows
what an investment in a class of the Portfolio would have earned over a
specified period of time (such as one, five or ten years) assuming that all
distributions and dividends by the Portfolio were reinvested in the same class
on the reinvestment dates during the period. Total return does not take into
account any federal or state income taxes that may be payable on dividends and
distributions or upon redemption. The "yield" of the Municipal Bond Portfolio
refers to the income generated by an investment in the Portfolio over a
one-month or 30-day period, while the "yield" of the Money Market and Municipal
Money Market Portfolios refers to the income generated by an investment in the
Portfolio over a seven-day period (which period will be stated in the
advertisement). This income is then "annualized." That is, the amount of income
generated by the investment during that 30- or seven-day period is assumed to be
generated each 30-day period for twelve periods or each week over a 52-week
period, and is shown as a percentage of the investment. The "effective yield" is
calculated similarly but, when annualized, the income earned on an investment in
the Portfolio is assumed to be reinvested. The "effective yield" will be
 
                                       35
<PAGE>
slightly higher than the "yield" because of the compounding effect of this
assumed reinvestment. A "tax equivalent yield" is the "yield" of the Portfolio
increased by an amount based on an assumed rate of tax for a shareholder. For
further information concerning these figures, see "Calculation of Yield and
Total Return" in the Statement of Additional Information. The Fund may also use
comparative performance information in marketing the Portfolios' shares,
including data from Lipper Analytical Services, Inc., Donoghue's Money Fund
Report, other industry publications, business periodicals, rating services and
market indices.
 
    The performance figures for Class B shares will generally be lower than
those for Class A shares because of the distribution fee charged to Class B
shares.
 
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
 
FIXED INCOME, MUNICIPAL BOND AND MORTGAGE-BACKED SECURITIES PORTFOLIOS
 
    All income dividends and capital gains distributions for a class of shares
of each Non-Money Portfolio will be automatically reinvested in additional
shares of such class at net asset value, except that, upon written notice to the
Fund or by checking off the appropriate box in the Distribution Option Section
on the Account Registration Form, a shareholder may elect to receive income
dividends and capital gains distributions in cash.
 
   
    Each Non-Money Portfolio expects to distribute substantially all of its
taxable net investment income in the form of monthly dividends. Net realized
capital gains of each Non-Money Portfolio, if any, after reduction for any tax
loss carryforwards will also be distributed annually.
    
 
    Undistributed net investment income is included in each Non-Money
Portfolio's net assets for the purpose of calculating net asset value per share.
Therefore, on the "ex-dividend" date, the net asset value per share excludes the
dividend (I.E., is reduced by the per share amount of the dividend). Dividends
paid shortly after the purchase of shares by an investor, although in effect a
return of capital, are taxable to shareholders subject to income tax.
 
    Because of the distribution fee and any other expenses that may be
attributable to the Class B shares, the net income attributable to and the
dividends payable on Class B shares will be lower than the net income
attributable to and the dividends payable on Class A shares. As a result, the
net asset value per share of the classes of each Non-Money Portfolio will differ
at times. Expenses of each Non-Money Portfolio allocated to a particular class
of shares will be borne on a pro rata basis by each outstanding share of that
class.
 
MONEY MARKET AND MUNICIPAL MONEY MARKET PORTFOLIOS
 
    Net investment income is computed and dividends declared as of 1:00 p.m.
(Eastern time), on each day. Such dividends are payable to Municipal Money
Market Portfolio shareholders of record as of 11:00 a.m. (Eastern time) on that
day and to Money Market Portfolio shareholders of record as of 12:00 noon
(Eastern time) on that day, if the Fund and Custodian Bank are open for
business. This means that shareholders whose purchase orders become effective as
of 12:00 noon (for the Money Market Portfolio) or 11:00 a.m. (for the Municipal
Money Market Portfolio) receive the dividend for that day. Dividends declared
for Saturdays, Sundays and holidays are payable to shareholders of record as of
4:00 p.m. on the last preceding day the Fund and its Custodian Bank were open
for business.
 
                                       36
<PAGE>
    For the purpose of calculating dividends, net income of each Money Portfolio
shall consist of interest earned, including any discount or premium ratably
amortized to the date of maturity, minus estimated expenses of the Money
Portfolio.
 
    Each Money Portfolio's daily dividends are accrued throughout the month and
are distributed on the fifteenth calendar day of each month (or next business
day if the fifteenth calendar day falls on a holiday or weekend). Dividends of
each Money Portfolio are payable in additional shares, except that, upon written
notice to the Fund or by checking off the appropriate box in the Distribution
Option Section on the Account Registration Form, a shareholder may elect to
receive income dividends and any capital gains distributions in cash.
 
    Each shareholder receives a monthly statement summarizing activity in the
account. If at any time a shareholder wishes to withdraw all of the funds in an
account, the proceeds will be sent to the shareholder by wire or check,
according to the shareholder's instructions. If the withdrawal is by wire, a
check in the amount of the income to the shareholder's account through the day
of withdrawal will be mailed to the shareholder on the next business day.
Withdrawals by check will include accrued income through the date of withdrawal.
 
    Net realized short-term capital gains, if any, of each Money Portfolio are
to be distributed whenever the Board of Directors determine that such
distributions would be in the best interest of shareholders, but in any event,
at least once a year. The Money Portfolios do not expect to realize any
long-term capital gains. Should any such gains be realized, they will be
distributed annually.
 
    It is an objective of management to maintain the price per share of each
Money Portfolio as computed for the purpose of sales and redemptions at exactly
$1.00. In the event the Board of Directors determine that a deviation from the
$1.00 per share price may exist which may result in a material dilution or other
unfair results to investors or existing shareholders, they will take corrective
action they regard as necessary and appropriate, including the sale of
instruments from a Money Portfolio prior to maturity to realize capital gains or
losses; shortening average portfolio maturity; withholding dividends; making a
special capital distribution; or redemptions of shares in kind.
 
                                     TAXES
 
GENERAL
 
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
 
    No attempt has been made to present a detailed explanation of the federal,
state, or local income tax treatment of a Portfolio or its shareholders.
Accordingly, shareholders are urged to consult their tax advisors regarding
specific questions as to federal, state and local income taxes.
 
    Each Portfolio is treated as a separate entity for federal income tax
purposes and is not combined with the Fund's other Portfolios. Each Portfolio
intends to qualify for the special tax treatment afforded regulated investment
companies under Subchapter M of the Code, so that the Portfolio will be relieved
of federal income tax on that part of its net investment income and net capital
gain that is distributed to shareholders.
 
                                       37
<PAGE>
   
    Each Portfolio intends to distribute substantially all of its taxable net
investment income (including, for this purpose, net short-term capital gain) to
shareholders. Dividends from a Portfolio's net investment income (other than
"exempt-interest dividends," described below) are taxable to shareholders as
ordinary income, whether received in cash or in additional shares. Distributions
of net capital gain (the excess of net long-term capital gain over net
short-term capital loss) are taxable to shareholders as long-term capital gain,
regardless of how long shareholders have held their shares. Distributions of net
investment income and net capital gain are not eligible for the corporate
dividends-received deduction. Each Portfolio will send reports annually to its
shareholders of the federal income tax status of all distributions made during
the preceding year.
    
 
    Each Portfolio intends to make sufficient distributions or deemed
distributions of its ordinary income and capital gain net income (the excess of
short-term and long-term capital gain over short-term and long-term capital
loss, including any available capital loss carryforwards) prior to the end of
each calendar year to avoid liability for federal excise tax.
 
    Dividends and other distributions declared by a Portfolio in October,
November or December of any year and payable to shareholders of record on a date
in such month will be deemed to have been paid by the Portfolio and received by
the shareholders on December 31 of that year if the distributions are paid by
the Portfolio at any time during the following January.
 
   
    The Fund may be required to withhold and remit to the U.S. Treasury 31% of
any dividends, capital gains distributions and redemption proceeds paid to any
individual or certain other non-corporate shareholder (1) who has failed to
provide a correct taxpayer identification number (generally an individual's
social security number or non-individual's employer identification number) on
the Application Form, (2) who is subject to backup withholding by the Internal
Revenue Service, or (3) who has not certified to the Fund that such shareholder
is not subject to backup withholding. This backup withholding is not an
additional tax, and any amounts withheld may be credited against the
shareholder's ultimate U.S. tax liability.
    
 
    The sale, exchange or redemption of shares will result in taxable gain or
loss to the selling, exchanging or redeeming shareholder, depending upon whether
the fair market value of the redemption proceeds exceed or are less than the
shareholder's adjusted basis in the sold, exchanged or redeemed shares. If
capital gain distributions have been made with respect to shares that are sold
at a loss after being held for six months or less, then the loss is treated as a
long-term capital loss to the extent of the capital gain distributions.
 
    Conversion of shares between classes are not taxable events to the
shareholder.
 
    Shareholders are urged to consult with their tax advisors concerning the
application of state and local income taxes to investments in a Portfolio, which
may differ from the federal income tax consequences described above.
 
THE MUNICIPAL BOND AND MUNICIPAL MONEY MARKET PORTFOLIOS
 
    The dividends payable by the Municipal Bond and the Municipal Money Market
Portfolios from net tax-exempt interest from municipal bonds and notes will
qualify as "exempt-interest dividends" if, at the close of each quarter of its
taxable year, at least 50% of the value of its total assets consists of
securities the interest on which is excludable from gross income. Each of the
Municipal Bond and Municipal Money Market Portfolios intends to invest a
sufficient portion of its assets in municipal bonds and notes to qualify to pay
"exempt-interest dividends."
 
                                       38
<PAGE>
    Exempt-interest dividends are excludable from a shareholder's gross income
for regular income tax purposes. However, the receipt of such dividends may have
collateral federal income tax consequences, including alternative minimum tax
consequences. In addition, the receipt of exempt-interest dividends may cause
persons receiving Social Security or Railroad Retirement benefits to be taxable
on a portion of such benefits. See the Statement of Additional Information.
Current federal tax law limits the types of volume of bonds qualifying for the
federal income tax exemption of interest, which may have an effect on the
ability of the Portfolios to purchase sufficient amounts of tax-exempt
securities to satisfy the Code's requirement for the payment of exempt-interest
dividends.
 
    All or a portion of the interest on indebtedness incurred or continued by an
investor to purchase or carry shares is not deductible for federal income tax
purposes. Furthermore, entities or persons who are "substantial users" (or
persons related to "substantial users") of facilities financed by "private
activity bonds" or "industrial development bonds" should consult their tax
advisors before purchasing shares of the Portfolios. See the Statement of
Additional Information.
 
    The Portfolios will report annually to their shareholders the portion of
dividends that is taxable and the portion that is tax-exempt based on income
received by the Portfolios during the year to which the dividends relate.
 
    The exemption of dividends paid by the Municipal Bond and Municipal Money
Market Portfolio for Federal income tax purposes may not result in similar
exemptions under the laws of a particular state or local taxing authority. Each
of the Municipal Bond and Municipal Money Market Portfolio will report annually
to its shareholders the percentage and source, on a state-by-state basis, of
interest income earned on municipal bonds and municipal notes held by the
Portfolio during the preceding year.
 
    THE TAX DISCUSSION SET FORTH ABOVE IS INCLUDED FOR GENERAL INFORMATION ONLY.
PROSPECTIVE INVESTORS SHOULD CONSULT THEIR OWN TAX ADVISERS WITH RESPECT TO THE
TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN A PORTFOLIO.
 
                             PORTFOLIO TRANSACTIONS
 
    The Adviser selects the brokers or dealers that will execute the purchases
and sales of investment securities for each of the Fund's portfolios. The
Adviser seeks the best execution of all portfolio transactions. A portfolio may
pay higher commission rates than the lowest available when the Adviser believes
it is reasonable to do so in light of the value of the research, statistical,
and pricing services provided by the broker effecting the transaction.
 
    It is not the Fund's practice to allocate brokerage or principal business on
the basis of sales of shares which may be made through intermediary brokers or
dealers. However, the Adviser may, consistent with NASD rules, place portfolio
orders with qualified broker-dealers who recommend the applicable portfolio to
their clients or who act as agents in the purchase of shares of the portfolio
for their clients.
 
    Subject to the overriding objective of obtaining the best execution of
orders, the Fund may use broker-dealer affiliates of the Adviser, including
Morgan Stanley, to effect portfolio brokerage transactions under procedures
adopted by the Fund's Board of Directors. For such transactions, the commission
rates and other
 
                                       39
<PAGE>
remuneration paid to Morgan Stanley or other affiliates must be fair and
reasonable in comparison to those of other broker-dealers for comparable
transactions involving similar securities being purchased or sold during a
comparable time period.
 
PORTFOLIO TURNOVER
 
   
    The Portfolios generally do not invest for short-term trading purposes,
however, when circumstances warrant, each Portfolio may sell investment
securities without regard to the length of time they have been held. Market
conditions in a given year could result in a higher or lower portfolio turnover
rate than expected and the Portfolios will not consider portfolio turnover rate
a limiting factor in making investment decisions consistent with their
respective objectives and policies. For the fiscal year ended December 31, 1996,
the Fixed Income Portfolio had a portfolio turnover rate of 183%. As portfolio
turnover increases, the Portfolios may expect to pay correspondingly increased
brokerage and trading costs. In addition to transaction costs, higher portfolio
turnover may result in the realization of capital gains. As discussed under
"Taxes," to the extent net short-term capital gains are realized, any
distributions resulting from such gains are considered ordinary income for
federal income tax purposes.
    
 
                              GENERAL INFORMATION
 
DESCRIPTION OF COMMON STOCK
 
   
    The Fund was organized as a Maryland corporation on June 16, 1988. The
Articles of Incorporation, as amended and restated, permit the Fund to issue up
to 35 billion shares of common stock, with $.001 par value per share. Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number of shares the Fund is authorized to issue without the approval of the
shareholders of the Fund. The Board of Directors has the power to designate one
or more classes of shares of common stock and to classify and reclassify any
unissued shares with respect to such classes. The shares of common stock of each
portfolio are currently classified into two classes, the Class A shares and
Class B shares, except for the International Small Cap, Money Market and
Municipal Money Market Portfolios, which offer only Class A shares.
    
 
    The shares of each Portfolio, when issued, will be fully paid,
nonassessable, fully transferable and redeemable at the option of the holder.
The shares have no preference as to conversion, exchange, dividends, retirement
or other features and have no pre-emptive rights. The shares of each Portfolio
have non-cumulative voting rights, which means that the holders of more than 50%
of the shares voting for the election of Directors can elect 100% of the
Directors if they choose to do so. Persons or organizations owning 25% or more
of the outstanding shares of a Portfolio may be presumed to "control" (as that
term is defined in the 1940 Act) that Portfolio. Under Maryland law, the Fund is
not required to hold an annual meeting of its shareholders unless required to do
so under the 1940 Act.
 
REPORTS TO SHAREHOLDERS
 
    The Fund will send to its shareholders annual and semi-annual reports; the
financial statements appearing in annual reports are audited by independent
accountants. Monthly unaudited portfolio data is also available from the Fund
upon request.
 
    In addition, the Adviser, or its agent, as Transfer Agent, will send to each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
 
                                       40
<PAGE>
CUSTODIAN
 
    Chase is the Fund's custodian for domestic and certain foreign assets. Chase
is not an affiliate of the Adviser or the Distributor. Morgan Stanley Trust
Company, Brooklyn, New York ("MSTC"), an affiliate of the Adviser and the
Distributor, acts as the Fund's custodian for assets held outside the United
States and employs subcustodians approved by the Board of Directors of the Fund
in accordance with regulations of the Securities and Exchange Commission for the
purpose of providing custodial services for such assets. MSTC may also hold
certain domestic assets for the Fund. For more information on the custodians,
see "General Information -- Custody Arrangements" in the Statement of Additional
Information.
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
    Chase Global Funds Services Company, 73 Tremont Street, Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
 
INDEPENDENT ACCOUNTANTS
 
   
    Price Waterhouse LLP serves as independent accountants for the Fund and
audits its annual financial statements.
    
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       41
<PAGE>
   MORGAN STANLEY INSTITUTIONAL FUND, INC.
  FIXED INCOME, MUNICIPAL BOND, MORTGAGE-BACKED SECURITIES,
   MONEY MARKET AND MUNICIPAL MONEY MARKET PORTFOLIOS
   P.O. BOX 2798, BOSTON, MA 02208-2798
 
                           ACCOUNT REGISTRATION FORM
 
<TABLE>
<C>   <S>                                            <C>
      ACCOUNT INFORMATION                            If you need assistance in filling out this form for the Morgan Stanley
      Fill in where applicable                       Institutional Fund, please contact your Morgan Stanley representative
                                                     or call us toll free 1-(800)-548-7786. Please print all items except
                                                     signature, and mail to the Fund at the address above.
  A)  REGISTRATION
      1. INDIVIDUAL
      2. JOINT TENANTS
         (RIGHTS OF SURVIVORSHIP PRESUMED UNLESS
         TENANCY IN COMMON
         IS INDICATED)
</TABLE>
 
1.
         First Name    Initial         Last Name
2.
         First Name    Initial         Last Name
         First Name    Initial         Last Name
 
<TABLE>
<C>   <S>                                            <C>
      3. CORPORATIONS,
         TRUSTS AND OTHERS
         Please call the Fund for additional
      documents that may be required to set up
      account and to authorize transactions.
</TABLE>
 
3.
 
<TABLE>
<S>                     <C>                 <C>                   <C>               <C>
Type of Registration:   / / INCORPORATED    / / UNINCORPORATED    / / PARTNERSHIP   / / UNIFORM GIFT/TRANSFER TO MINOR
                                            ASSOCIATION                               (ONLY ONE CUSTODIAN AND MINOR PERMITTED)
</TABLE>
 
/ / TRUST ________________________  / / OTHER (Specify) ________________________
<TABLE>
<C>        <S>                             <C>
       B)  MAILING ADDRESS
           Please fill in completely,
           including telephone number(s).
 
<CAPTION>
       B)
 
<CAPTION>
</TABLE>
 
/ / United States Citizen  / / Resident Alien
                   Street or P.O. Box
                   City
                   State                   Zip
Home Telephone No.                   Business Telephone No.
/ / Non-Resident Alien:
Permanent Address (Where you reside permanently for tax purposes)
                   Street Address
                   City
                   Country                   Postal Code
Home Telephone No.                    Business Telephone No.
 
Current Mailing Address (If different from Permanent Address)
                   Street Address
                   City
                   Country
Postal Code
Home Telephone No.                   Business Telephone No.
 
<TABLE>
<C>   <S>                                            <C>                                  <C>
  C)  TAXPAYER                                       Enter your Taxpayer Identification Number. For most individual
      IDENTIFICATION                                 taxpayers, this is your Social Security Number.
      NUMBER
      1. INDIVIDUAL
      2.   JOINT TENANTS
           (RIGHTS OF SURVIVORSHIP PRESUMED UNLESS
           TENANCY IN COMMON
           IS INDICATED)
      For Custodian account
      of a minor (Uniform
      Gifts/Transfers to Minor
      Acts), give the Social
      Security Number of
      the minor
                                                                                          OR
                                                     1.         TAXPAYER IDENTIFICATION                      SOCIAL SECURITY
                                                     NUMBER ("TIN")                                NUMBER ("SSN")
                                                                                              OR
                                                     2.                             TIN
                                                                                                                             SSN
                                                                                              OR
                                                     TIN
                                                                                                                             SSN
                                                     IMPORTANT TAX INFORMATION
                                                     You (as a payee) are required by law to provide us (as payer) with your
                                                     correct TIN(s) or SSN(s). Accounts that have a missing or incorrect
                                                     TIN(s) or SSN(s) will be subject to backup withholding at a 31% rate on
                                                     dividends, distributions and other payments. If you have not provided us
                                                     with your correct TIN(s) or SSN(s), you may be subject to a $50 penalty
                                                     imposed by the Internal Revenue Service.
                                                     Backup withholding is not an additional tax; the tax liability of
                                                     persons subject to backup withholding will be reduced by the amount of
                                                     tax withheld. If withholding results in an overpayment of taxes, a
                                                     refund may be obtained.
                                                     You may be notified that you are subject to backup withholding under
                                                     Section 3406(a)(1)(C) of the Internal Revenue Code because you have
                                                     underreported interest or dividends or you were required to, but failed
                                                     to, file a return which would have included a reportable interest or
                                                     dividend payment.
</TABLE>
 
<PAGE>
 
   
<TABLE>
<C>   <S>                                  <C>                             <C>                   <C>
  D)  PORTFOLIO AND                        For Purchase of the following   / / Class A Shares $  / / Class B Shares $
      CLASS SELECTION                      Portfolio(s):                   / / Class A Shares $  / / Class B Shares $
      (Class A shares minimum $500,000     Fixed Income Portfolio          / / Class A Shares $  / / Class B Shares $
      and Class B shares minimum $100,000  Municipal Bond Portfolio        / / Class A Shares $
      for each of the Fixed Income,        Mortgage-Backed Securities      / / Class A Shares $
      Municipal Bond and Mortgage-Backed   Portfolio
      Securities Portfolios. Minimum       Money Market Portfolio
      $50,000 for each of the Money        Municipal Money Market
      Market and Municipal Money Market    Portfolio
      Portfolios). Please indicate
      Portfolio, class and amount.
                                                                           Total Initial Investment $
</TABLE>
    
 
<TABLE>
<C>   <S>                        <C>
  E)  METHOD OF
      INVESTMENT
      Please indicate
      portfolio, manner of
      payment.
</TABLE>
 
Payment by:
 
/ / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND,
INC.--PORTFOLIO NAME)
 
<TABLE>
<S>                                                                          <C>
/ / Exchange $ From                                                                     -- - - - - - - - - - -- - -
                            Name of Portfolio                                                   Account No.
/ / Account previously established by:  / / Phone exchange  / / Wire on                 -- - - - - - - - - - -- - -
                                                                                      Account No.               (Check
                                                                                (Previously assigned by the Fund)     Digit)
                                                                                                                          Date
</TABLE>
 
<TABLE>
<C>   <S>                        <C>
  F)  DISTRIBUTION               Income dividends and capital gains distributions (if any) to
      OPTION                     be reinvested in additional shares unless either box below
                                 is checked.
                                 / / Income dividends to be paid in cash, capital gains
                                 distributions (if any) in shares.
                                 / / Income dividends and capital gains distributions (if
                                 any) to be paid in cash.
</TABLE>
 
<TABLE>
<C>   <S>                             <C>                                       <C>
  G)  TELEPHONE                       / / I/we hereby authorize the Fund and
      REDEMPTION                      its agents to honor any telephone         Name of COMMERCIAL Bank (Not Savings
      AND EXCHANGE                    requests to wire redemption proceeds to   Bank)
      OPTION                          the commercial bank indicated at right    Bank Account No.
      Please select at time of        and/or mail redemption proceeds to the
      initial application if you      name and address in which my/our fund
      wish to redeem or exchange      account is registered if such requests                                        Bank
      shares by telephone. A          are believed to be authentic.                                                  ABA
      SIGNATURE GUARANTEE IS          The Fund and the Fund's Transfer Agent                                         No.
      REQUIRED IF BANK ACCOUNT IS     will employ reasonable procedures to
      NOT REGISTERED IDENTICALLY TO   confirm that instructions communicated    Name(s) in which your BANK Account is
      YOUR FUND ACCOUNT.              by telephone are genuine. These           Established
      TELEPHONE REQUESTS FOR          procedures include requiring the
      REDEMPTIONS OR EXCHANGE WILL    investor to provide certain personal      Bank's Street
      NOT BE HONORED UNLESS THE BOX   identification information at the time    Address
      IS CHECKED.                     an account is opened and prior to
                                      effecting each transaction requested by   City  State  Zip
                                      telephone. In addition, all telephone
                                      transaction requests will be recorded
                                      and investors may be required to provide
                                      additional telecopied written
                                      instructions of transaction requests.
                                      Neither the Fund nor the Transfer Agent
                                      will be responsible for any loss,
                                      liability, cost or expense for following
                                      instructions received by telephone that
                                      it reasonably believes to be genuine.
</TABLE>
 
   
<TABLE>
<C>   <S>                                  <C>
  H)  INTERESTED PARTY
      OPTION                                                                                                Name
      In addition to the account
      statement sent to my/our registered
      address, I/we hereby authorize the                                                                   Address
      Fund to mail duplicate statements
      to the name and address provided at  City         State         Zip Code
      right.
</TABLE>
    
 
<TABLE>
<C>   <S>                                  <C>
  I)  DEALER
      INFORMATION
                                           Representative Name              Representative No.             Branch
                                           No.
</TABLE>
 
<TABLE>
<C>   <S>                                  <C>
  J)  SIGNATURE OF
      ALL HOLDERS
      AND TAXPAYER
      CERTIFICATION
      Sign Here ,
</TABLE>
 
<TABLE>
<S>                                  <C>
The undersigned certify that I/we have full authority and legal capacity
to purchase and redeem shares of the Fund and affirm that I/we have
received a current Prospectus of the Morgan Stanley Institutional Fund,
Inc. and agree to be bound by its terms.
  BY SIGNING THIS APPLICATION, I/WE HEREBY CERTIFY UNDER PENALTIES OF
PERJURY THAT THE INFORMATION ON THIS APPLICATION IS COMPLETE AND CORRECT
AND THAT AS REQUIRED BY FEDERAL LAW (PLEASE CHECK APPLICABLE BOXES
BELOW):
 
/ / U.S. CITIZEN(S)/TAXPAYER(S):
 
      / / I/WE CERTIFY THAT (1) THE NUMBER(S) SHOWN ABOVE ON THIS FORM
          IS/ARE THE CORRECT SSN(S) OR TIN(S) AND (2) I/WE ARE NOT
          SUBJECT TO ANY BACKUP WITHHOLDING EITHER BECAUSE (A) I/WE ARE
          EXEMPT FROM BACKUP WITHHOLDING; (B) I/WE HAVE NOT BEEN
          NOTIFIED BY THE INTERNAL REVENUE SERVICE ("IRS") THAT I/WE ARE
          SUBJECT TO BACKUP WITHHOLDING AS A RESULT OF A FAILURE TO
          REPORT ALL INTEREST OR DIVIDENDS; OR (C) THE IRS HAS NOTIFIED
          ME/US THAT I AM/WE ARE NO LONGER SUBJECT TO BACKUP
          WITHHOLDING.
 
      / / IF NO TIN(S) OR SSN(S) HAS/HAVE BEEN PROVIDED ABOVE, I/WE HAVE
          APPLIED, OR INTEND TO APPLY, TO THE IRS OR THE SOCIAL SECURITY
          ADMINISTRATION FOR A TIN OR A SSN AND I/WE UNDERSTAND THAT IF
          I/ WE DO NOT PROVIDE EITHER NUMBER TO CHASE GLOBAL FUNDS
          SERVICES COMPANY ("CGFSC") WITHIN 60 DAYS OF THE DATE OF THIS
          APPLICATION OR IF I/WE FAIL TO FURNISH MY/OUR CORRECT SSN(S)
          OR TIN(S), I/WE MAY BE SUBJECT TO A PENALTY AND A 31% BACKUP
          WITHHOLDING ON DISTRIBUTIONS AND REDEMPTION PROCEEDS. (PLEASE
          PROVIDE EITHER NUMBER ON IRS FORM W-9). YOU MAY REQUEST SUCH
          FORM BY CALLING CGFSC AT 800-282-4404.
 
/ / NON-U.S. CITIZEN(S)/TAXPAYER(S)
  UNDER PENALTIES OF PERJURY, I/WE CERTIFY THAT I/WE ARE NOT U.S.
CITIZENS OR RESIDENTS AND I/WE ARE EXEMPT FOREIGN PERSONS AS DEFINED BY
THE INTERNAL REVENUE SERVICE.
 
THE INTERNAL REVENUE SERVICE DOES NOT REQUIRE YOUR CONSENT TO ANY
PROVISION OF THIS DOCUMENT OTHER THAN THE CERTIFICATIONS REQUIRED TO
AVOID BACKUP WITHHOLDING.
 
                                     (X)
(X)                                  Signature (if joint account, both
Signature            Date            must sign)      Date
</TABLE>
 
<PAGE>
<PAGE>
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
 
  NO DEALER, SALES REPRESENTATIVE OR ANY OTHER PERSON HAS BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS HAVING BEEN AUTHORIZED BY THE FUND OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION TO
ANY PERSON TO WHOM IT IS UNLAWFUL TO MAKE SUCH OFFER OR SOLICITATION IN SUCH
JURISDICTION.
 
                           --------------------------
 
                               TABLE OF CONTENTS
 
   
<TABLE>
<S>                                                 <C>
                                                    PAGE
                                                    ----
Fund Expenses.....................................    2
Financial Highlights..............................    4
Prospectus Summary................................    9
Investment Objectives and Policies................   13
Additional Investment Information.................   18
Investment Limitations............................   23
Management of the Fund............................   23
Purchase of Shares................................   26
Redemption of Shares..............................   31
Shareholder Services..............................   33
Valuation of Shares...............................   34
Performance Information...........................   35
Dividends and Capital Gains Distributions.........   36
Taxes.............................................   37
Portfolio Transactions............................   39
General Information...............................   40
Account Registration Form
</TABLE>
    
 
                             FIXED INCOME PORTFOLIO
                            MUNICIPAL BOND PORTFOLIO
                      MORTGAGE-BACKED SECURITIES PORTFOLIO
                             MONEY MARKET PORTFOLIO
                        MUNICIPAL MONEY MARKET PORTFOLIO
 
                               PORTFOLIOS OF THE
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
 
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
                      P.O. Box 2798, Boston, MA 02208-2798
 
- ---------------------------------
- ---------------------------------
- ---------------------------------
- ---------------------------------
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
     ----------------------------------------------------------------------
                        SMALL CAP VALUE EQUITY PORTFOLIO
                             VALUE EQUITY PORTFOLIO
                               BALANCED PORTFOLIO
                         GLOBAL FIXED INCOME PORTFOLIO
                              HIGH YIELD PORTFOLIO
                               PORTFOLIOS OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
                                ----------------
   
    Morgan Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company, or mutual fund, which offers redeemable shares in
a series of diversified and non-diversified investment portfolios
("portfolios"). The Fund is designed to provide clients with attractive
alternatives for meeting their investment needs. The Fund currently consists of
twenty-nine portfolios representing a broad range of investment choices. This
prospectus (the "Prospectus") pertains to the Class A and the Class B shares of
the Small Cap Value Equity, Value Equity, Balanced, Global Fixed Income and High
Yield Portfolios (each, a "Portfolio," and collectively, the "Portfolios"). The
Class A and Class B shares currently offered by the Portfolios have different
minimum investment requirements and fund expenses. Shares of the portfolios are
offered with no sales charge, exchange fee or redemption fee, (except that the
International Small Cap Portfolio may impose a transaction fee).
    
    THE HIGH YIELD PORTFOLIO INVESTS PREDOMINANTLY IN LOWER RATED BONDS,
COMMONLY REFERRED TO AS "JUNK BONDS." BONDS OF THIS TYPE ARE CONSIDERED TO BE
SPECULATIVE WITH REGARD TO THE PAYMENT OF INTEREST AND RETURN OF PRINCIPAL.
INVESTORS SHOULD CAREFULLY ASSESS THE RISKS ASSOCIATED WITH AN INVESTMENT IN
THIS PORTFOLIO. SEE "RISK FACTORS RELATING TO INVESTING IN HIGH YIELD
SECURITIES."
    The Fund is designed to meet the investment needs of discerning investors
who place a premium on quality and personal service. With Morgan Stanley Asset
Management Inc. as Adviser and Administrator (the "Adviser" and the
"Administrator"), and with Morgan Stanley & Co. Incorporated ("Morgan Stanley")
as Distributor, the Fund makes available to institutional and high net worth
individual investors a series of portfolios which benefit from the investment
expertise and commitment to excellence associated with Morgan Stanley and its
affiliates.
    This Prospectus is designed to set forth concisely the information about the
Fund that a prospective investor should know before investing and it should be
retained for future reference. The Fund offers additional portfolios which are
described in other prospectuses and under "Prospectus Summary" below. The Fund
currently offers the following portfolios: (i) GLOBAL AND INTERNATIONAL EQUITY
- -- Active Country Allocation, Asian Equity, Emerging Markets, European Equity,
Global Equity, Gold, International Equity, International Magnum, International
Small Cap, Japanese Equity and Latin American Portfolios; (ii) U.S. EQUITY --
Aggressive Equity, Emerging Growth, Equity Growth, Small Cap Value Equity,
Technology, U.S. Real Estate and Value Equity Portfolios; (iii) EQUITY AND FIXED
INCOME -- Balanced Portfolio; (iv) FIXED INCOME -- Emerging Markets Debt, Fixed
Income, Global Fixed Income, High Yield and Municipal Bond Portfolios; and (v)
MONEY MARKET -- Money Market and Municipal Money Market Portfolios. Additional
information about the Fund is contained in a "Statement of Additional
Information", dated May 1, 1997, which is incorporated herein by reference. The
Statement of Additional Information and the prospectuses pertaining to the other
portfolios of the Fund are available upon request and without charge by writing
or calling the Fund at the address and telephone number set forth above.
  THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES AND
EXCHANGE COMMISSION, NOR HAS THE SECURITIES AND EXCHANGE COMMISSION PASSED UPON
        THE ACCURACY OR ADEQUACY OF THIS PROSPECTUS. ANY REPRESENTATION
                     TO THE CONTRARY IS A CRIMINAL OFFENSE.
 
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1997.
<PAGE>
                                 FUND EXPENSES
 
    The following table illustrates the expenses and fees that a shareholder of
each Portfolio will incur:
 
<TABLE>
<CAPTION>
                                                                                            GLOBAL
                                                                                             FIXED      HIGH
                                             SMALL CAP VALUE   VALUE EQUITY    BALANCED     INCOME      YIELD
SHAREHOLDER TRANSACTION EXPENSES            EQUITY PORTFOLIO     PORTFOLIO     PORTFOLIO   PORTFOLIO  PORTFOLIO
- ------------------------------------------  -----------------  -------------  -----------  ---------  ---------
<S>                                         <C>                <C>            <C>          <C>        <C>
Maximum Sales Load Imposed on Purchases
  Class A.................................           None             None          None     None       None
  Class B.................................           None             None          None     None       None
Maximum Sales Load Imposed on Reinvested
 Dividends
  Class A.................................           None             None          None     None       None
  Class B.................................           None             None          None     None       None
Deferred Sales Load
  Class A.................................           None             None          None     None       None
  Class B.................................           None             None          None     None       None
Redemption Fees
  Class A.................................           None             None          None     None       None
  Class B.................................           None             None          None     None       None
Exchange Fees
  Class A.................................           None             None          None     None       None
  Class B.................................           None             None          None     None       None
</TABLE>
   
<TABLE>
<CAPTION>
      ANNUAL FUND OPERATING EXPENSES
<S>                                         <C>                <C>            <C>          <C>        <C>
- ------------------------------------------
 
<CAPTION>
                                                                                            GLOBAL
                                                                                            FIXED       HIGH
                                             SMALL CAP VALUE   VALUE EQUITY    BALANCED     INCOME     YIELD
(AS A PERCENTAGE OF AVERAGE NET ASSETS)     EQUITY PORTFOLIO     PORTFOLIO     PORTFOLIO   PORTFOLIO  PORTFOLIO
                                            -----------------  -------------  -----------  --------   --------
<S>                                         <C>                <C>            <C>          <C>        <C>
Management Fee (Net of Fee Waivers)**
  Class A.................................          0.53%            0.42%         0.00%    0.18%     0.375%
  Class B.................................          0.53%            0.42%         0.00%    0.18%     0.375%
12b-1 Fees
  Class A.................................           None             None          None    None       None
  Class B.................................          0.25%            0.25%         0.25%    0.15%*     0.25%
Other Expenses
  Class A.................................          0.47%            0.28%         0.70%    0.32%      0.32%
  Class B.................................          0.47%            0.28%         0.70%    0.32%      0.32%
                                                   ------           ------    -----------  --------   --------
Total Operating Expenses (Net of Fee
 Waivers)**
  Class A.................................          1.00%            0.70%         0.70%    0.50%     0.695%
  Class B.................................          1.25%            0.95%         0.95%    0.65%     0.945%
                                                   ------           ------    -----------  --------   --------
                                                   ------           ------    -----------  --------   --------
</TABLE>
    
 
- --------------------------
 *The Distributor has agreed to waive 0.10% of the 0.25% distribution fee it is
  entitled to receive from this Portfolio.
   
**The Adviser has agreed to waive its management fee and/or reimburse each
  Portfolio, if necessary, if such fees would cause the total annual operating
  expenses of the Portfolios to exceed a specified percentage of their
  respective average daily net assets. As a result of these reductions, the
  Management Fees stated above are lower than the contractual fees stated under
  "Management of the Fund." The Adviser reserves the right to terminate any of
  its fee waivers and/or expense reimbursements at any time in its sole
  discretion. For further
    
 
                                       2
<PAGE>
   
  information on Fund expenses, see "Management of the Fund." Set forth below,
  for each Portfolio, are the management fees and total operating expenses
  absent such fee waivers and/or expense reimbursements as a percent of the
  average daily net assets of the Class A shares and Class B shares,
  respectively.
    
 
                                       3
<PAGE>
 
   
<TABLE>
<CAPTION>
                                                                                    TOTAL OPERATING EXPENSES
                                                                                       ABSENT FEE WAIVERS
                                                                 MANAGEMENT FEE     ------------------------
PORTFOLIO                                                      ABSENT FEE WAIVERS    CLASS A      CLASS B
- ------------------------------------------------------------  --------------------  ----------  ------------
<S>                                                           <C>                   <C>         <C>
Small Cap Value Equity......................................            0.85%            1.32%        1.69%
Value Equity................................................            0.50%            0.78%        1.03%
Balanced....................................................            0.50%            1.32%        1.68%
Global Fixed Income.........................................            0.40%            0.72%        0.86%
High Yield..................................................           0.375%           0.695%       0.945%
</TABLE>
    
 
   
    The purpose of the table above is to assist the investor in understanding
the various expenses that an investor in the Portfolios will bear directly or
indirectly. Expenses and fees are based on actual figures for the fiscal year
ended December 31, 1996. Due to the continuous nature of Rule 12b-1 fees, long
term Class B shareholders may pay more than the equivalent of the maximum
front-end sales charges otherwise permitted by the National Association of
Securities Dealers, Inc. ("NASD") Conduct Rules.
    
 
    The following example illustrates the expenses that you would pay on a
$1,000 investment assuming (1) a 5% annual rate of return and (2) redemption at
the end of each time period. As noted above, the Portfolios charge no redemption
fees of any kind. The following example is based on total operating expenses of
the Portfolios after fee waivers.
 
   
<TABLE>
<CAPTION>
                                                                       1 YEAR       3 YEARS      5 YEARS     10 YEARS
                                                                     -----------  -----------  -----------  -----------
<S>                                                                  <C>          <C>          <C>          <C>
Small Cap Value Equity Portfolio
  Class A..........................................................   $      10    $      32    $      55    $     122
  Class B..........................................................          13           40           69          151
Value Equity Portfolio
  Class A..........................................................           7           22           39           87
  Class B..........................................................          10           30           53          117
Balanced Portfolio
  Class A..........................................................           7           22           39           87
  Class B..........................................................          10           30           53          117
Global Fixed Income
  Class A..........................................................           5           16           28           63
  Class B..........................................................           7           21           36           81
High Yield Portfolio
  Class A..........................................................           8           24           42           93
  Class B..........................................................          10           32           55          122
</TABLE>
    
 
    THIS EXAMPLE SHOULD NOT BE CONSIDERED A REPRESENTATION OF PAST OR FUTURE
EXPENSES OR PERFORMANCE. ACTUAL EXPENSES MAY BE GREATER OR LESS THAN THOSE
SHOWN.
 
                                       4
<PAGE>
                              FINANCIAL HIGHLIGHTS
 
   
    The following tables provide financial highlights for the Class A and Class
B shares for each of the Portfolios for the periods presented. The audited
financial highlights for the Portfolios' shares for each of the periods
presented are part of the Fund's financial statements which appear in the Fund's
December 31, 1996 Annual Report to Shareholders which are incorporated by
reference in the Fund's Statement of Additional Information. The Portfolios'
financial highlights for each of the periods presented have been audited by
Price Waterhouse LLP, whose unqualified report thereon is also incorporated by
reference in the Statement of Additional Information. Additional performance
information is included in the Annual Report. The Annual Report and the
financial statements therein, along with the Statement of Additional
Information, are available at no cost from the Fund at the address and telephone
number noted on the cover page of this Prospectus. After October 31, 1992, the
Fund changed its fiscal year end to December 31. The following information
should be read in conjunction with the financial statements and notes thereto.
    
 
                                       5
<PAGE>
                        SMALL CAP VALUE EQUITY PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                          CLASS A                                      CLASS B
                                          ------------------------------------------------------------------------   ------------
                                                                                                      PERIOD FROM    PERIOD FROM
                                                                                                      DECEMBER 17,    JANUARY 2,
                                           YEAR ENDED     YEAR ENDED     YEAR ENDED     YEAR ENDED      1992* TO      1996*** TO
                                          DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   OCTOBER 31,    DECEMBER 31,
                                              1996           1995           1994           1993           1992           1996
                                          ------------   ------------   ------------   ------------   ------------   ------------
<S>                                       <C>            <C>            <C>            <C>            <C>            <C>
NET ASSET VALUE, BEGINNING OF PERIOD....  $ 11.91        $ 10.80        $ 11.10        $ 10.14        $ 10.00        $ 11.95
                                          ------------   ------------   ------------   ------------    ------        ------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1).............     0.32           0.30           0.28           0.24           0.01           0.23
  Net Realized and Unrealized Gain
   (Loss) on Investments................     2.36           1.82         (0.01)           0.90           0.13           2.38
    Total from Investment Operations         2.68           2.12           0.27           1.14           0.14           2.61
DISTRIBUTIONS
  Net Investment Income.................   (0.32)         (0.38)         (0.27)         (0.18)             --         (0.30)
  Net Realized Gain.....................   (3.38)         (0.63)         (0.30)             --             --         (3.38)
                                          ------------   ------------   ------------   ------------    ------        ------------
    Total Distributions.................   (3.70)         (1.01)         (0.57)         (0.18)             --         (3.68)
                                          ------------   ------------   ------------   ------------    ------        ------------
NET ASSET VALUE, END OF PERIOD..........  $ 10.89        $ 11.91        $ 10.80        $ 11.10        $ 10.14        $ 10.88
                                          ------------   ------------   ------------   ------------    ------        ------------
                                          ------------   ------------   ------------   ------------    ------        ------------
TOTAL RETURN............................    22.99%         20.63%          2.53%         11.33%          1.40%         22.33%
                                          ------------   ------------   ------------   ------------    ------        ------------
                                          ------------   ------------   ------------   ------------    ------        ------------
RATIOS AND SUPPLEMENTAL DATA:
  Net Assets, End of Period
   (Thousands)..........................  $23,970        $51,919        $40,033        $26,775        $ 5,974        $ 1,689
  Ratio of Expenses to Average Net
   Assets (1)...........................     1.00%          1.00%          1.00%          1.00%          1.00%**        1.24%**
  Ratio of Net Investment Income to
   Average Net Assets (1)...............     2.20%          2.60%          2.67%          2.56%          1.64%**        1.93%**
  Portfolio Turnover Rate...............       32%            36%            22%            29%             0%            32%
  Average Commission Rate#..............  $0.0402            N/A            N/A            N/A            N/A        $0.0402
</TABLE>
    
 
- ------------------------------
 
   
<TABLE>
<C><S>                             <C>            <C>            <C>            <C>            <C>            <C>
(1) Effect of voluntary expense
    limitation during the period:
     Per share benefit to net in-
      vestment income............       $0.04         $0.02           $0.03          $0.06         $0.13           $0.05
   Ratios before expense
    limitation:
     Expenses to Average Net As-
      sets.......................        1.32  %        1.21  %        1.26  %        1.68  %      23.14   %**       1.69  %**
     Net Investment Income (Loss)
      to Average Net Assets......        1.89  %        2.39  %        2.41  %        1.88  %     (20.50   )%**       1.50  %**
</TABLE>
    
 
   
  * Commencement of Operations.
    
 
   
 ** Annualized
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
   
 # Beginning with fiscal year 1996, the Portfolio is required to disclose the
   average commission rate per share it paid for portfolio trades, on which
   commissions were charged, during the period.
    
 
                                       6
<PAGE>
                             VALUE EQUITY PORTFOLIO
   
<TABLE>
<CAPTION>
                                                    CLASS A
                           ---------------------------------------------------------
                            YEAR ENDED     YEAR ENDED     YEAR ENDED     YEAR ENDED
                           DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,
                               1996           1995           1994           1993
                           ------------   ------------   ------------   ------------
<S>                        <C>            <C>            <C>            <C>
NET ASSET VALUE,
 BEGINNING OF PERIOD.....  $ 13.94        $ 11.50        $ 12.63        $ 11.31
                           ------------   ------------   ------------   ------------
INCOME FROM INVESTMENT
 OPERATIONS
Net Investment Income
 (1).....................     0.41           0.38           0.40           0.37
Net Realized and
 Unrealized Gain (Loss)
 on Investments..........     2.27           3.30         (0.55)           1.31
                           ------------   ------------   ------------   ------------
    Total from Investment
     Operations..........     2.68           3.68         (0.15)           1.68
                           ------------   ------------   ------------   ------------
DISTRIBUTIONS
  Net Investment
   Income................   (0.41)         (0.47)         (0.40)         (0.36)
  Net Realized Gain......   (2.32)         (0.77)         (0.58)             --
                           ------------   ------------   ------------   ------------
    Total
     Distributions.......   (2.73)         (1.24)         (0.98)         (0.36)
                           ------------   ------------   ------------   ------------
NET ASSET VALUE, END OF
 PERIOD..................  $ 13.89        $ 13.94        $ 11.50        $ 12.63
                           ------------   ------------   ------------   ------------
                           ------------   ------------   ------------   ------------
TOTAL RETURN.............    19.73%         33.69%         (1.29)%        15.14%
                           ------------   ------------   ------------   ------------
                           ------------   ------------   ------------   ------------
RATIOS AND SUPPLEMENTAL
 DATA:
  Net Assets, End of
   Period (Thousands)      $106,128       $147,365       $73,406        $54,598
  Ratio of Expenses to
   Average Net Assets
   (1)...................     0.70%          0.70%          0.70%          0.70%
  Ratio of Net Investment
   Income to Average Net
   Assets (1)............     2.62%          3.01%          3.37%          3.23%
  Portfolio Turnover
   Rate..................       42%            43%            33%            51%
  Average Commission
   Rate#.................  $0.0434            N/A            N/A            N/A
 
<CAPTION>
 
                            TWO MONTHS
                              ENDED        YEAR ENDED
                           DECEMBER 31,   OCTOBER 31,
                               1992           1992
                           ------------   ------------
<S>                        <C>
NET ASSET VALUE,
 BEGINNING OF PERIOD.....  $ 10.71        $ 10.24
                           ------------   ------------
INCOME FROM INVESTMENT
 OPERATIONS
Net Investment Income
 (1).....................     0.08           0.38
Net Realized and
 Unrealized Gain (Loss)
 on Investments..........     0.52           0.48
                           ------------   ------------
    Total from Investment
     Operations..........     0.60           0.86
                           ------------   ------------
DISTRIBUTIONS
  Net Investment
   Income................       --         (0.39)
  Net Realized Gain......       --             --
                           ------------   ------------
    Total
     Distributions.......       --         (0.39)
                           ------------   ------------
NET ASSET VALUE, END OF
 PERIOD..................  $ 11.31        $ 10.71
                           ------------   ------------
                           ------------   ------------
TOTAL RETURN.............     5.60%          8.51%
                           ------------   ------------
                           ------------   ------------
RATIOS AND SUPPLEMENTAL
 DATA:
  Net Assets, End of
   Period (Thousands)      $27,541        $25,013
  Ratio of Expenses to
   Average Net Assets
   (1)...................     0.70%**        0.70%
  Ratio of Net Investment
   Income to Average Net
   Assets (1)............     4.41%**        3.72%
  Portfolio Turnover
   Rate..................        9%            56%
  Average Commission
   Rate#.................      N/A            N/A
 
<CAPTION>
                             CLASS B
                           ------------
                           PERIOD FROM
                            JANUARY 2,
                            1996*** TO
                           DECEMBER 31,
                               1996
                           ------------
NET ASSET VALUE,
 BEGINNING OF PERIOD.....  $ 14.06
                            ------
INCOME FROM INVESTMENT
 OPERATIONS
Net Investment Income
 (1).....................     0.29
Net Realized and
 Unrealized Gain (Loss)
 on Investments..........     2.25
                            ------
    Total from Investment
     Operations..........     2.54
                            ------
DISTRIBUTIONS
  Net Investment
   Income................   (0.39)
  Net Realized Gain......   (2.32)
                            ------
    Total
     Distributions.......   (2.71)
                            ------
NET ASSET VALUE, END OF
 PERIOD..................  $ 13.89
                            ------
                            ------
TOTAL RETURN.............    18.57%
                            ------
                            ------
RATIOS AND SUPPLEMENTAL
 DATA:
  Net Assets, End of
   Period (Thousands)      $ 2,555
  Ratio of Expenses to
   Average Net Assets
   (1)...................     0.95%**
  Ratio of Net Investment
   Income to Average Net
   Assets (1)............     2.33%**
  Portfolio Turnover
   Rate..................       42%
  Average Commission
   Rate#.................  $0.0434
</TABLE>
    
 
- ----------------------------------
   
<TABLE>
<C> <S>                    <C>            <C>
(1) Effect of voluntary
     expense limitation
     during the period:
      Per share benefit
       to net investment
       income............       $0.01       $0.01
    Ratios before expense
     limitation:
      Expenses to Average
       Net Assets........        0.78  %        0.77 %
      Net Investment
       Income to
       Average Net
       Assets............        2.55  %        2.94 %
 
<CAPTION>
(1)
<C>                 <C>            <C>            <C>            <C>
 
         $0.01          $0.03          $0.01           $0.01         $0.01
 
          0.80   %       0.95   %       1.20   %**       0.84  %      1.03   %**
 
          3.27   %       2.98   %       3.91   %**       3.58  %      2.26   %**
 
<CAPTION>
 
</TABLE>
    
 
   
 ** Annualized
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
   
 # Beginning with fiscal year 1996, the Portfolio is required to disclose the
   average commission rate per share it paid for portfolio trades, on which
   commissions were paid, during the period.
    
 
                                       6
<PAGE>
                               BALANCED PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                                                         CLASS B
                                                            CLASS A                                    ------------
                         ----------------------------------------------------------------------------- PERIOD FROM
                                                                              TWO MONTHS                JANUARY 2,
                          YEAR ENDED   YEAR ENDED   YEAR ENDED   YEAR ENDED     ENDED      YEAR ENDED   1996*** TO
                         DECEMBER 31, DECEMBER 31, DECEMBER 31, DECEMBER 31, DECEMBER 31, OCTOBER 31,  DECEMBER 31,
                             1996         1995         1994         1993         1992         1992         1996
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
<S>                      <C>          <C>          <C>          <C>          <C>          <C>          <C>
NET ASSET VALUE,
 BEGINNING OF PERIOD..... $    9.98   $    8.96    $   11.13    $   11.31    $   11.00    $   10.61    $   10.02
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment Income
   (1)...................      0.52        0.39         0.42         0.44         0.10         0.58         0.34
  Net Realized and
   Unrealized Gain (Loss)
   on Investments........      0.54        1.62       (0.64)         0.79         0.21         0.42         0.65
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
    Total from Investment
     Operations..........      1.06        2.01       (0.22)         1.23         0.31         1.00         0.99
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
DISTRIBUTIONS
  Net Investment
   Income................    (0.48)      (0.50)       (0.49)       (0.41)           --       (0.58)       (0.46)
  In Excess of Net
   Investment Income.....      0.00+         --           --       (0.08)           --           --       (2.37)
  Net Realized Gain......    (2.37)      (0.49)       (1.46)       (0.06)           --       (0.03)       (2.83)
  In Excess of Net
   Realized Gain.........        --          --           --       (0.86)           --           --    $    8.18
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
    Total
     Distributions.......    (2.85)      (0.99)       (1.95)       (1.41)           --       (0.61)       10.24%
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
NET ASSET VALUE, END OF
 PERIOD.................. $    8.19   $    9.98    $    8.96    $   11.13    $   11.31    $   11.00
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
TOTAL RETURN.............     10.93%      23.63%       (2.32)%      12.09%        2.82%        9.57%       10.24%
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
                         ------------ ------------ ------------ ------------ ------------ ------------ ------------
RATIOS AND SUPPLEMENTAL DATA:
  Net Assets, End of
   Period (Thousands).... $   5,992   $  22,642    $  18,492    $  29,684    $  39,984    $  40,332    $   2,197
  Ratio of Expenses to
   Average Net Assets
   (1)...................      0.70%       0.70%        0.70%        0.70%        0.70%**      0.70%        0.95%**
  Ratio of Net Investment
   Income to Average Net
   Assets (1)............      3.93%       4.10%        4.13%        3.88%        5.29%**      5.21%        3.73%**
  Portfolio Turnover
   Rate..................        22%         26%          44%         136%           4%          40%          22%
  Average Commission
   Rate#.................   $0.0397         N/A          N/A          N/A          N/A          N/A      $0.0397
</TABLE>
    
 
- ------------------------------
 
   
<TABLE>
<C>  <S>                 <C>          <C>          <C>          <C>          <C>          <C>          <C>
 (1) Effect of voluntary
      expense limitation
      during the period:
       Per share benefit
        to net investment
        income...........      $0.08      $0.03         $0.03        $0.04        $0.01         $0.01       $0.07
     Ratios before
      expense limitation:
       Expenses to
        Average Net
        Assets...........       1.32  %       1.02  %       0.95  %       1.02  %       1.00   **        0.79 %      1.68%  **
       Net Investment
        Income to Average
        Net Assets.......       3.31  %       3.78  %       3.88  %       3.56  %       4.99   **        5.12 %      3.00%  **
</TABLE>
    
 
   
 ** Annualized
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
   
  + Amount is less than $0.01 per share.
    
 
   
 # Beginning with fiscal year 1996, the Portfolio is required to disclose the
   average commission rate per share it paid for portfolio trades, on which
   commissions were charged, during the period.
    
 
                                       7
<PAGE>
                         GLOBAL FIXED INCOME PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                                                         CLASS B
                                                                                                         -------
                                                                                                         PERIOD
                                                                                                          FROM
                                                             CLASS A                                     JANUARY
                           ---------------------------------------------------------------------------     2,
                                                                               TWO MONTHS                1996***
                           YEAR ENDED   YEAR ENDED   YEAR ENDED   YEAR ENDED     ENDED      YEAR ENDED     TO
                            DECEMBER     DECEMBER     DECEMBER     DECEMBER     DECEMBER     OCTOBER     DECEMBER
                              31,          31,          31,          31,          31,          31,         31,
                              1996         1995         1994         1993         1992         1992       1996
                           ----------   ----------   ----------   ----------   ----------   ----------   -------
<S>                        <C>          <C>          <C>          <C>          <C>          <C>          <C>
NET ASSET VALUE,
 BEGINNING OF PERIOD.....  $  11.22     $  10.29     $  11.68     $  11.26     $  11.41     $  10.61     $11.23
                           ----------   ----------   ----------   ----------   ----------   ----------   -------
INCOME FROM INVESTMENT
 OPERATIONS
Net Investment Income
 (1).....................      0.61         0.76         0.70         0.69         0.14         0.53      0.48
Net Realized and
 Unrealized Gain (Loss)
 on Investments                0.08         1.15       (1.38)         0.90       (0.29)         0.55      0.18
                           ----------   ----------   ----------   ----------   ----------   ----------   -------
    Total from Investment
     Operations..........      0.69         1.91       (0.68)         1.59       (0.15)         1.08      0.66
                           ----------   ----------   ----------   ----------   ----------   ----------   -------
DISTRIBUTIONS
  Net Investment
   Income................    (0.61)       (0.98)       (0.40)       (0.79)           --       (0.27)     (0.60)
  In Excess of Net
   Investment Income.....        --           --           --       (0.22)           --           --        --
  Net Realized Gain......        --           --       (0.31)       (0.16)           --       (0.01)        --
                           ----------   ----------   ----------   ----------   ----------   ----------   -------
    Total
     Distributions.......    (0.61)       (0.98)       (0.71)       (1.17)           --       (0.28)     (0.60)
                           ----------   ----------   ----------   ----------   ----------   ----------   -------
NET ASSET VALUE, END OF
 PERIOD..................  $  11.30     $  11.22     $  10.29     $  11.68     $  11.26     $  11.41     $11.29
                           ----------   ----------   ----------   ----------   ----------   ----------   -------
                           ----------   ----------   ----------   ----------   ----------   ----------   -------
TOTAL RETURN.............      6.44%       19.32%       (6.08)%      15.34%       (1.31)%      10.29%     6.12%
                           ----------   ----------   ----------   ----------   ----------   ----------   -------
                           ----------   ----------   ----------   ----------   ----------   ----------   -------
RATIOS AND SUPPLEMENTAL
 DATA:
  Net Assets, End of
   Period (Thousands)....  $112,888     $102,852     $130,675     $172,468     $ 92,897     $ 94,847     $1,559
  Ratio of Expenses to
   Average Net Assets
   (1)...................      0.50%        0.50%        0.50%        0.50%        0.50%**      0.50%     0.65%**
  Ratio of Net Investment
   Income to Average Net
   Assets (1)............      5.50%        6.79%        6.34%        5.99%        6.99%**      6.92%     5.28%**
  Portfolio Turnover
   Rate..................       258%         207%         171%         108%           9%         144%      258%
</TABLE>
    
 
- ----------------------------------
 
   
<TABLE>
<C><S>                        <C>          <C>          <C>          <C>          <C>          <C>          <C>
(1) Effect of voluntary
    expense limitation
    during the period:
     Per share benefit to
      net investment
      income................    $0.02         $0.02       $0.02        $0.02        $0.01         $0.03     $0.02
   Ratios before expense
    limitation:
     Expenses to Average Net
      Assets................     0.72   %     0.71   %     0.66   %     0.70   %     0.90   %**     0.86  % 0.86   %**
     Net Investment Income
      to Average Net
      Assets................     5.29   %     6.58   %     6.18   %     5.79   %     6.59   %**     6.56  % 5.08   %**
</TABLE>
    
 
   
 ** Annualized
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
                                       8
<PAGE>
                              HIGH YIELD PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                     CLASS A                                          CLASS B
                                ---------------------------------------------------------------------------------   -----------
                                                                                                      PERIOD FROM   PERIOD FROM
                                                                                        TWO MONTHS     SEPTEMBER    JANUARY 2,
                                YEAR ENDED    YEAR ENDED    YEAR ENDED    YEAR ENDED       ENDED       28, 1992*    1996*** TO
                                 DECEMBER      DECEMBER      DECEMBER      DECEMBER      DECEMBER         TO         DECEMBER
                                    31,           31,           31,           31,           31,       OCTOBER 31,       31,
                                   1996          1995          1994          1993          1992          1992          1996
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
<S>                             <C>           <C>           <C>           <C>           <C>           <C>           <C>
NET ASSET VALUE, BEGINNING OF
 PERIOD.......................  $  10.46      $   9.55      $  11.16      $   9.95      $   9.77      $  10.00      $  10.49
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
INCOME FROM INVESTMENT
 OPERATIONS
Net Investment Income (1).....      1.03          1.14          0.97          0.90          0.14          0.08          0.98
  Net Realized and Unrealized
   Gain (Loss) on
   Investments................      0.47          0.97        (1.40)          1.21          0.19        (0.31)          0.45
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
    Total from Investment
     Operations...............      1.50          2.11        (0.43)          2.11          0.33        (0.23)          1.43
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
DISTRIBUTIONS
  Net Investment Income.......    (1.05)        (1.20)        (0.97)        (0.90)        (0.15)            --        (1.02)
  In Excess of Net Investment
   Income.....................    (0.00)+           --            --            --            --            --            --
  Net Realized Gain...........        --            --        (0.21)            --            --            --            --
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
    Total Distributions.......    (1.05)        (1.20)        (1.18)        (0.90)        (0.15)            --        (1.02)
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
NET ASSET VALUE, END OF
 PERIOD.......................  $  10.91      $  10.46      $   9.55      $  11.16      $   9.95      $   9.77      $  10.90
TOTAL RETURN..................     15.01%        23.35%        (4.18)%       22.11%         3.41%        (2.30)%       14.37%
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
                                -----------   -----------   -----------   -----------   -----------   -----------   -----------
RATIOS AND SUPPLEMENTAL DATA:
  Net Assets, End of Period
   (Thousands)................  $ 95,663      $ 62,245      $ 97,223      $ 74,500      $ 20,194      $ 16,950      $  5,665
  Ratio of Expenses to Average
   Net Assets (1).............      0.75%         0.75%         0.75%         0.75%         0.75%**       0.75%**       1.00%**
  Ratio of Net Investment
   Income to Average Net
   Assets (1).................      9.78%        11.09%         9.42%         8.70%         8.96%**       9.89%**       9.49%**
  Portfolio Turnover Rate.....       117%           90%           74%          104%           24%            9%          117%
</TABLE>
    
 
- ----------------------------------
 
   
<TABLE>
<C><S>                             <C>           <C>           <C>           <C>           <C>           <C>           <C>
(1) Effect of voluntary expense
    limitation during the period:
     Per share benefit to net
      investment income..........  $   0.01      $   0.01      $  0.001      $   0.02      $   0.01      $   0.01      $   0.01
   Ratios before expense
    limitation:
     Expenses to Average Net
      Assets.....................      0.82%         0.83%         0.76%         0.96%         1.62%**       1.23%**       1.05%**
     Net Investment Income to
      Average Net Assets.........      9.71%        11.01%         9.41%         8.49%         8.09%**       9.41%**       9.44%**
</TABLE>
    
 
   
  * Commencement of Operations.
    
 
   
 ** Annualized
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
   
  + Amount is less than $0.01 per share.
    
 
                                       9
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
 
    The Fund consists of twenty-nine portfolios, offering institutional
investors and high net worth individual investors a broad range of investment
choices coupled with the advantages of a no-load mutual fund with Morgan Stanley
and its affiliates providing customized services as Adviser, Administrator and
Distributor. Each portfolio offers Class A shares and, except for the
International Small Cap, Money Market and Municipal Money Market Portfolios,
also offers Class B shares. Each portfolio has its own investment objective and
policies designed to meet its specific goals. The investment objective of each
Portfolio described in this Prospectus is as follows:
 
   
    - The SMALL CAP VALUE EQUITY PORTFOLIO seeks high long-term total return by
      investing in undervalued equity securities of small- to medium-sized
      companies.
    
 
   
    - The VALUE EQUITY PORTFOLIO seeks high total return by investing in equity
      securities which the Adviser believes to be undervalued relative to the
      stock market in general at the time of purchase.
    
 
   
    - The BALANCED PORTFOLIO seeks high total return while preserving capital by
      investing in a combination of undervalued equity securities and fixed
      income securities.
    
 
   
    - The GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real rate
      of return while preserving capital by investing in fixed income securities
      of issuers throughout the world, including U.S. issuers.
    
 
   
    - The HIGH YIELD PORTFOLIO seeks to maximize total return by investing in a
      diversified portfolio of high yield fixed income securities that offer a
      yield above that generally available on debt securities in the three
      highest rating categories of the recognized rating services.
    
 
    The other portfolios of the Fund are described in other Prospectuses which
may be obtained from the Fund at the address and phone number noted on the cover
page of this Prospectus. The investment objectives of these other portfolios are
listed below:
 
    GLOBAL AND INTERNATIONAL EQUITY:
 
    - The ACTIVE COUNTRY ALLOCATION PORTFOLIO seeks long-term capital
      appreciation by investing in accordance with country weightings determined
      by the Adviser in equity securities of non-U.S. issuers which, in the
      aggregate, replicate broad country indices.
 
    - The ASIAN EQUITY PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of Asian issuers.
 
    - The CHINA GROWTH PORTFOLIO seeks to provide long-term capital appreciation
      by investing primarily in equity securities of issuers in The People's
      Republic of China, Hong Kong and Taiwan.
 
    - The EMERGING MARKETS PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of emerging country issuers.
 
    - The EUROPEAN EQUITY PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of European issuers.
 
    - The GLOBAL EQUITY PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of issuers throughout the world,
      including U.S. issuers.
 
                                       10
<PAGE>
    - The GOLD PORTFOLIO seeks long-term capital appreciation by investing
      primarily in equity securities of foreign and domestic issuers engaged in
      gold-related activities.
 
    - The INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of non-U.S. issuers.
 
    - The INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of non-U.S. issuers domiciled in
      EAFE countries.
 
    - The INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital appreciation
      by investing primarily in equity securities of non-U.S. issuers with
      equity market capitalizations of less than $1 billion.
 
    - The JAPANESE EQUITY PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of Japanese issuers.
 
   
    - The LATIN AMERICAN PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of Latin American issuers and,
      from time to time, debt securities issued or guaranteed by Latin American
      governments or governmental entities.
    
 
    US EQUITY:
 
    - The AGGRESSIVE EQUITY PORTFOLIO seeks capital appreciation by investing
      primarily in corporate equity and equity-linked securities.
 
    - The EMERGING GROWTH PORTFOLIO seeks long-term capital appreciation by
      investing primarily in growth-oriented equity securities of small- to
      medium-sized corporations.
 
    - The EQUITY GROWTH PORTFOLIO seeks long-term capital appreciation by
      investing in growth-oriented equity securities of medium and large
      capitalization companies.
 
    - The MICROCAP PORTFOLIO seeks long-term capital appreciation by investing
      primarily in growth-oriented equity securities of small corporations.
 
    - The TECHNOLOGY PORTFOLIO seeks long-term capital appreciation by investing
      primarily in equity securities of companies that, in the opinion of the
      portfolio's investment adviser, are expected to benefit from their
      involvement in technology and technology-related industries.
 
    - The U.S. REAL ESTATE PORTFOLIO seeks to provide above average current
      income and long-term capital appreciation by investing primarily in equity
      securities of companies in the U.S. real estate industry, including real
      estate investment trusts.
 
    FIXED INCOME:
 
    - The EMERGING MARKETS DEBT PORTFOLIO seeks high total return by investing
      primarily in debt securities of government, government-related and
      corporate issuers located in emerging countries.
 
    - The FIXED INCOME PORTFOLIO seeks to produce a high total return consistent
      with the preservation of capital by investing in a diversified portfolio
      of fixed income securities.
 
    - The MORTGAGE-BACKED SECURITIES PORTFOLIO seeks to produce as high a level
      of current income as is consistent with the preservation of capital by
      investing primarily in a variety of investment-grade mortgage-backed
      securities.
 
                                       11
<PAGE>
    - The MUNICIPAL BOND PORTFOLIO seeks to produce a high level of current
      income consistent with preservation of principal by investing primarily in
      municipal obligations, the interest on which is exempt from federal income
      tax.
 
    MONEY MARKET:
 
    - The MONEY MARKET PORTFOLIO seeks to maximize current income and preserve
      capital while maintaining high levels of liquidity through investing in
      high quality money market instruments with remaining maturities of one
      year or less.
 
    - The MUNICIPAL MONEY MARKET PORTFOLIO seeks to maximize current tax-exempt
      income and preserve capital while maintaining high levels of liquidity
      through investing in high quality money market instruments with remaining
      maturities of one year or less which are exempt from federal income tax.
 
    THE CHINA GROWTH, MICROCAP AND MORTGAGE-BACKED SECURITIES PORTFOLIOS ARE
    CURRENTLY NOT BEING OFFERED.
 
INVESTMENT MANAGEMENT
 
   
    Morgan Stanley Asset Management Inc., a wholly owned subsidiary of Morgan
Stanley Group Inc., which, together with its affiliated asset management
companies, at March 31, 1997 had in excess of $118 billion in assets under
management as an investment manager or as a fiduciary adviser, acts as
investment adviser to the Fund and each of its Portfolios. See "Management of
the Fund -- Investment Adviser" and "Management of the Fund -- Administrator."
    
 
HOW TO INVEST
 
   
    Class A shares of each Portfolio are offered directly to investors at net
asset value with no sales commission or 12b-1 charges. Class B shares of each
Portfolio are offered at net asset value with no sales commission, but with a
12b-1 fee, which is accrued daily and paid quarterly, equal to 0.25% of the
Class B shares' average daily net assets on an annualized basis. The Distributor
has agreed to waive 0.10% of the 0.25% 12b-1 fee with respect to the Global
Fixed Income Portfolio. Share purchases may be made by sending investments
directly to the Fund or through the Distributor. The minimum initial investment,
generally, is $500,000 for Class A shares of each Portfolio and $100,000 for
Class B shares of each Portfolio. The minimum initial investment amount is
reduced for certain categories of investors. For additional information on how
to purchase shares and minimum initial investments, see "Purchase of Shares."
    
 
HOW TO REDEEM
 
    Class A shares or Class B shares of each Portfolio may be redeemed at any
time, without cost, at the net asset value per share of shares of the applicable
class next determined after receipt of the redemption request. The redemption
price may be more or less than the purchase price. Certain redemptions that
cause the value of an account to remain for a continuous 60-day period below the
minimum investment amount for Class A shares or for Class B shares may result in
involuntary redemption or automatic conversion. For additional information on
how to redeem shares and involuntary redemption or conversion, see "Purchase of
Shares -- Minimum Account Sizes and Involuntary Redemption of Shares" and
"Redemption of Shares."
 
                                       12
<PAGE>
RISK FACTORS
 
   
    The investment policies of each of the Portfolios entail certain risks and
considerations of which an investor should be aware. Each Portfolio may invest
in securities of foreign issuers and foreign currency forward contracts to hedge
currency risk associated with investments in non-U.S. dollar-denominated
securities, which are subject to certain risks not typically associated with
U.S. securities. The High Yield Portfolio may invest in non-publicly traded
securities, private placements and restricted securities and in lower rated and
unrated securities which are subject to additional risk factors. In particular:
(1) adverse economic and corporate changes and changes in interest rates may
have a greater impact on issuers of lower rated securities and may lead to
greater price volatility, and (2) such securities may be more difficult to value
accurately or sell in the secondary market. Because the Small Cap Value Equity
Portfolio seeks high long-term total return by investing primarily in small- to
medium-sized corporations which are more vulnerable to financial risks and other
risks than larger corporations, investments may involve a higher degree of risk
and price volatility than investments in the general equity markets. In
addition, each Portfolio may invest in repurchase agreements, lend its portfolio
securities and purchase securities on a when-issued or delayed delivery basis
and invest in money market instruments. The Portfolios may invest in certain
derivatives, including futures and options on futures and, except in the case of
the High Yield Portfolio, options. These investments entail certain costs and
risks, including imperfect correlation between the value of securities held by a
Portfolio and the value of the particular derivative instrument, and the risk
that a Portfolio could not close out a derivatives position when it would be
most advantageous to do so. Each Portfolio, except the Global Fixed Income and
High Yield Portfolios, may also invest indirectly in securities through
Depositary Receipts. Each Portfolio may invest in short-term or medium-term debt
securities or hold cash or cash equivalents for temporary defensive purposes.
Each of these investment strategies involves specific risks which are described
under "Investment Objectives and Policies" and "Additional Investment
Information" herein and under "Investment Objectives and Policies" in the
Statement of Additional Information.
    
 
                                       13
<PAGE>
                       INVESTMENT OBJECTIVES AND POLICIES
 
    The investment objective of each Portfolio is described below, together with
the policies the Portfolios employ in their efforts to achieve these objectives.
Each Portfolio's investment objective is a fundamental policy which may not be
changed without the approval of a majority of the Portfolio's outstanding voting
securities. There is no assurance that the Portfolios will attain their
objectives. In addition to the investments and strategies described below, the
Porfolios may invest in certain securities and obligations as set forth in
"Additional Investment Information" below and as described under "Investment
Objectives and Policies" in the Statement of Additional Information. The
investment policies described below are not fundamental policies and may be
changed without shareholder approval.
 
THE SMALL CAP VALUE EQUITY PORTFOLIO
 
   
    The investment objective of the Small Cap Value Equity Portfolio is to
provide high long-term total return by investing in equity securities of small-
to medium-sized corporations that the Adviser believes to be undervalued
relative to the stock market in general at the time of purchase. The Portfolio
invests primarily in corporations domiciled in the U.S. with market
capitalizations that range generally from $70 million up to $1 billion, but may
from time to time invest in similar size foreign corporations. Under normal
circumstances, the Portfolio will invest at least 65% of the value of its total
assets in equity securities of corporations whose equity market capitalization
is up to $1 billion. The Portfolio may invest up to 35% of the value of its
total assets in equity securities of corporations which are generally smaller
than the 500 largest corporations in the United States. With respect to the
Portfolio, equity securities include common and preferred stocks, convertible
securities, rights and warrants to purchase common stocks, and similar equity
interests, such as trusts or partnership interests. These investments may or may
not carry voting rights. The portfolio may, on occasion, invest in equity
securities of foreign issuers that trade on a U.S. exchange or over-the-counter
in the form of Depositary Receipts or common stocks.
    
 
    The Adviser invests with the philosophy that a diversified portfolio of
undervalued, small- to medium-sized companies will provide high total return in
the long run.
 
    Companies considered attractive will have the following characteristics:
 
        1.  The market prices of the stocks will be undervalued relative to the
    normal earning power of the companies;
 
        2.  Stock prices will be low relative to the intrinsic value of the
    companies' assets;
 
        3.  Stocks will most often have yields distinctly above the average of
    companies with similar capitalizations; and
 
        4.  Stocks will be of high quality, in the Adviser's judgment, as
    evaluated by the companies' balance sheets, income statements, franchises
    and product competitiveness.
 
    The thrust of this approach is to seek investments in stocks for which
investor enthusiasm is currently low, as reflected in their valuation, but which
have the financial and fundamental features, which, according to the Adviser's
assessment, will allow the stocks to achieve a higher valuation. Value is
achieved and exposure is reduced for the Portfolio when the investment
community's perceptions improve and the stocks approach what the Adviser
believes is fair valuation.
 
                                       14
<PAGE>
THE VALUE EQUITY PORTFOLIO
 
    The investment objective of the Value Equity Portfolio is to achieve high
total return (i.e., long-term growth of capital and high current income) by
investing in equity securities that the Adviser believes to be undervalued
relative to the stock market in general at the time of purchase. It seeks
superior market cycle total returns, with an emphasis on strong relative
performance in falling markets. The Portfolio invests primarily in equity
securities of large capitalization companies mainly domiciled in the United
States. With respect to the Portfolio, equity securities include common and
preferred stocks, convertible securities, and rights and warrants to purchase
common stocks. Under normal circumstances, the Portfolio will invest at least
65% of the value of its total assets in equity securities.
 
    The Adviser invests with the philosophy that a diversified portfolio of
undervalued equity securities will outperform the market over the long term, as
well as preserve principal in difficult market environments. Companies
considered attractive will have the following characteristics: 1) stocks most
often will have distinctly above average dividend yields, 2) the market prices
of the stocks will be undervalued relative to the normal earning power of the
company, 3) many stocks will sell at close to or below the replacement value of
their assets and 4) most stocks' market prices will have underperformed the
general market due to a lower level of investor expectations regarding the
company outlook. The thrust of this approach is to seek investments where
current investor enthusiasm is low, as reflected in their valuations. Exposure
is reduced when the investment community's perceptions improve and the company
approaches fair valuation.
 
    The Adviser takes a long-term investment approach by placing a strong
emphasis on its ability to determine attractive values and does not try to
determine short-term changes in the general market level. The Portfolio will
maintain diversity among industries by not investing more than 25% of its total
assets in equity securities of issuers in any one industry. The Portfolio may
invest up to 25% of its total assets in the equity securities of foreign
issuers, including Depositary Receipts.
 
THE BALANCED PORTFOLIO
 
    The investment objective of the Balanced Portfolio is to achieve high total
return while preserving capital by investing in a combination of undervalued
equity securities and fixed income securities. The Portfolio seeks strong total
returns in all market conditions, with a special emphasis on minimizing interim
declines during falling equity markets. It primarily invests in large
capitalization equity securities, intermediate-maturity bonds and cash
equivalents.
 
    The Adviser uses a valuation-driven balanced portfolio philosophy which
combines separate equity, fixed income and asset allocation strategies. The
equity investment approach is the same as that used for the Value Equity
Portfolio. This produces a portfolio of stocks with low price-to-earnings and
price-to-book ratios and high dividend yields. The fixed income strategy values
bonds using historical yield differentials. Short and intermediate government,
corporate and mortgage bonds are used exclusively to implement the Portfolio's
fixed income strategy. The asset allocation strategy shifts the stock/bond/cash
equivalent mix relative to calculated risk and return levels. All three
strategies use historical capital market behavior to reach conclusions.
 
    The Portfolio will typically maintain between 35% and 65% of its total
assets invested in equity securities, depending upon the Adviser's assessment of
market conditions. With respect to the Portfolio, equity securities include
common and preferred stocks, convertible securities, and rights and warrants to
purchase common
 
                                       15
<PAGE>
stocks. In overvalued equity markets, the common stock exposure will be at the
low end of this range. It is expected that equity exposure will average
approximately 55% over time. Up to 25% of the Portfolio's total assets may be
invested in the securities of foreign issuers.
 
    Fixed income securities in which the Portfolio may invest include U.S.
Government securities, mortgage-backed securities, corporate bonds, bank
obligations and other short-term money market instruments. The average maturity
of the fixed income securities in the Portfolio will, under normal
circumstances, be approximately five years, although this will vary with
changing market conditions.
 
THE GLOBAL FIXED INCOME PORTFOLIO
 
    The Global Fixed Income Portfolio seeks to produce an attractive real rate
of return while preserving capital by investing in fixed income securities of
U.S. and foreign issuers denominated in U.S. dollars and in other currencies.
The Portfolio seeks to achieve its objectives by investing in U.S. government
securities, foreign government securities, securities of supranational entities,
Eurobonds, and corporate bonds with varying maturities. In selecting portfolio
securities, the Adviser evaluates the currency, market, and individual features
of the securities being considered for investment. At least 65% of the total
assets of the Portfolio will be invested in fixed income securities under normal
circumstances.
 
    The Adviser seeks to minimize investment risk by investing only in high
quality debt securities. U.S. Government securities that the Portfolio may
invest in include obligations issued by the U.S. Government, such as U.S.
Treasury securities, as well as those guaranteed or backed by the full faith and
credit of the United States, such as obligations of the Government National
Mortgage Association and The Export-Import Bank. The Portfolio may also invest
in obligations issued or guaranteed by U.S. Government agencies or
instrumentalities where the Portfolio must look principally to the issuing or
guaranteeing agency for ultimate repayment. The Portfolio may invest in
obligations issued or guaranteed by foreign governments and their political
subdivisions, authorities, agencies or instrumentalities, and by supranational
entities (such as the World Bank, The European Economic Community, The Asian
Development Bank and the European Coal and Steel Community). Investment in
foreign government securities will be limited to those of developed nations
which the Adviser believes pose limited credit risk. These countries currently
include Australia, Austria, Belgium, Canada, Denmark, Finland, France, Ireland,
Italy, Japan, Luxembourg, Netherlands, New Zealand, Norway, Spain, Sweden,
Switzerland, The United Kingdom and Germany. Corporate and supranational
obligations which the Portfolio will invest in will be limited to those rated A
or better by Moody's Investors Services, Inc. ("Moody's"), Standard & Poor's
Ratings Group ("S&P") or IBCA Ltd., or if unrated, to those that are of
comparable quality in the determination of the Board of Directors and the
Adviser.
 
    The Adviser's approach to multicurrency fixed income management is strategic
and value-based and designed to produce an attractive real rate of return. The
Adviser's assessment of the bond markets and currencies is based on an analysis
of real interest rates. Current nominal yields of securities are adjusted for
inflation prevailing in each currency sector using an analysis of past and
projected inflation rates. The Portfolio's aim is to invest in bond markets
which offer the most attractive real returns relative to inflation.
 
    The Portfolio will have a neutral investment position in medium-term
securities (i.e., those with a remaining maturity of between three and seven
years) and will respond to changing interest rate levels by shortening or
lengthening portfolio maturity through investment in longer- or shorter-term
instruments. For example, the Portfolio will respond to high levels of real
interest rates through a lengthening in portfolio maturity. Current
 
                                       16
<PAGE>
and historical yield spreads among the three main market segments -- the
Government, Foreign and Euro markets -- guide the Adviser's selection of markets
and particular securities within those markets. The analysis of currencies is
made independent of the analysis of markets. Value in foreign exchange is
determined by relative purchasing power parity of a given currency. The
Portfolio seeks to invest in currencies currently undervalued based on
purchasing power parity. The Adviser analyzes current account and capital
account performance and real interest rates to adjust for shorter-term currency
flows.
 
THE HIGH YIELD PORTFOLIO
 
   
    The High Yield Portfolio seeks to maximize total return by investing in a
diversified portfolio of high yield fixed income securities that offer a yield
above that generally available on debt securities in the four highest rating
categories of the recognized rating services. The Portfolio normally invests
between 80% and 100% of its total assets in these higher yielding securities,
which generally entails increased credit and market risk. To mitigate these
risks the Portfolio will diversify its holdings by issuer, industry and credit
quality, but investors should carefully review the section below entitled "Risk
Factors Relating to Investing in High Yield Securities."
    
 
    Appendix A to this Prospectus sets forth a description of the corporate bond
rating categories of Moody's and S&P. Corporate bonds rated below Baa by Moody's
or BBB by S&P are considered speculative. Securities in the lowest rating
categories may have predominantly speculative characteristics or may be in
default. Ratings of S&P and Moody's represent their opinions of the quality of
bonds and other debt securities they undertake to rate at the time of issuance.
However, ratings are not absolute standards of quality and may not reflect
changes in an issuer's creditworthiness. Accordingly, although the Adviser will
consider ratings, it will perform its own analysis and will not rely principally
on ratings. The Adviser will consider, among other things, the price of the
security and the financial history and condition, the prospects and the
management of an issuer in selecting securities for the Portfolio. The Portfolio
may buy unrated securities that the Adviser believes are comparable to rated
securities and are consistent with the Portfolio's objective and policies. The
Adviser may vary the average maturity of the securities in the Portfolio without
limit and there is no restriction on the maturity of any individual security.
 
   
    The Portfolio may acquire fixed income securities of both U.S. and foreign
issuers, including debt obligations (e.g., bonds, debentures, notes, equipment
lease certificates, equipment trust certificates, conditional sales contracts,
commercial paper and obligations issued or guaranteed by the U.S. Government,
any foreign government with which the United States maintains relations or any
of their respective political subdivisions, agencies or instrumentalities) and
preferred stock. The Portfolio may not invest more than 5% of its total assets
at time of acquisition in either (1) equipment lease certificates, equipment
trust certificates and conditional sales contracts or (2) limited partnership
interests. The Portfolio may neither invest more than 10% of its total assets in
foreign securities nor invest more than 5% of its total assets in foreign
governmental issuers in any one country. The Portfolio's fixed income securities
may have equity features, such as conversion rights or warrants, and the
Portfolio may invest up to 10% of its total assets in equity securities other
than preferred stock (e.g., common stocks, warrants and rights and limited
partnership interests). The Portfolio may invest up to 20% of its total assets
in fixed income securities that are investment grade (i.e., rated in one of the
top four categories or comparable) and have maturities of one year or less. The
Portfolio may invest in or own securities of companies in various stages of
financial restructuring, bankruptcy or reorganization which are not currently
paying interest or dividends. The total value, at time of purchase, of the sum
of all such securities will not exceed 10% of the value of the Portfolio's total
assets.
    
 
                                       17
<PAGE>
    The Portfolio may also invest in zero coupon, pay-in-kind or deferred
payment securities. Zero coupon securities are securities that are sold at a
discount to par value and securities on which interest payments are not made
during the life of the security. Upon maturity, the holder is entitled to
receive the par value of the security. While interest payments are not made on
such securities, holders of such securities are deemed to have received "phantom
income" annually. Because the Portfolio will distribute its "phantom income" to
shareholders, to the extent that shareholders elect to receive dividends in cash
rather than reinvesting such dividends in additional shares of the Portfolio, it
will have fewer assets with which to purchase income producing securities. The
Portfolio accrues income with respect to these securities prior to the receipt
of cash payments. Pay-in-kind securities are securities that have interest
payable by delivery of additional securities. Upon maturity, the holder is
entitled to receive the aggregate par value of the securities. Deferred payment
securities are securities that remain zero coupon securities until a
predetermined date, at which time the stated coupon rate becomes effective and
interest becomes payable at regular intervals. Zero coupon, pay-in-kind and
deferred payment securities may be subject to greater fluctuation in value and
lesser liquidity in the event of adverse market conditions than comparably rated
securities paying cash interest at regular interest payment periods.
 
    RISK FACTORS RELATING TO INVESTING IN HIGH YIELD SECURITIES.  Fixed income
securities are subject to the risk of an issuer's inability to meet principal
and interest payments on the obligations (credit risk), and may also be subject
to price volatility due to such factors as interest rate sensitivity, market
perception of the creditworthiness of the issuer and general market liquidity
(market risk). Lower rated or unrated (i.e., high yield) securities are more
likely to react to developments affecting market and credit risk than are more
highly rated securities, which react to movements in the general level of
interest rates primarily. The market values of fixed-income securities tend to
vary inversely with the level of interest rates. Yields and market values of
high yield securities will fluctuate over time, reflecting not only changing
interest rates, but the market's perception of credit quality and the outlook
for economic growth. When economic conditions appear to be deteriorating, medium
to lower rated securities may decline in value due to heightened concern over
credit quality, regardless of prevailing interest rates. Fluctuations in the
value of the Portfolio's investments will be reflected in the Portfolio's net
asset value per share. The Adviser considers both credit risk and market risk in
making investment decisions for the Portfolio. Investors should carefully
consider the relative risks of investing in high yield securities and understand
that such securities are not generally meant for short-term investing.
 
    The high yield market is still relatively new and its recent growth
parallels a long period of economic expansion and an increase in merger,
acquisition and leveraged buyout activity. Adverse economic developments may
disrupt the market for high yield securities, and severely affect the ability of
issuers, especially highly leveraged issuers, to service their debt obligations
or to repay their obligations upon maturity. In addition, the secondary market
for high yield securities, which is concentrated in relatively few market
makers, may not be as liquid as the secondary market for more highly rated
securities. As a result, the Adviser could find it more difficult to sell these
securities or may be able to sell the securities only at prices lower than if
such securities were widely traded. Prices realized upon the sale of lower rated
or unrated securities, under these circumstances, may be less than the prices
used in calculating the Portfolio's net asset value.
 
    Prices for high yield securities may be affected by legislative and
regulatory developments. These developments could adversely affect the
Portfolio's net asset value and investment practices, the secondary market for
high yield securities, the financial condition of issuers of these securities
and the value of outstanding high yield
 
                                       18
<PAGE>
securities. For example, federal legislation requiring the divestiture by
federally insured savings and loan associations of their investments in high
yield bonds and limiting the deductibility of interest by certain corporate
issuers of high yield bonds adversely affected the market in recent years.
 
    Lower rated or unrated debt obligations also present risks based on payment
expectations. If an issuer calls the obligations for redemption, the Portfolio
may have to replace the security with a lower yielding security, resulting in a
decreased return for investors. If the Portfolio experiences unexpected net
redemptions, it may be forced to sell its higher rated securities, resulting in
a decline in the overall credit quality of the Portfolio's investment portfolio
and increasing the exposure of the Portfolio to the risks of high yield
securities.
 
    The table below provides a summary of ratings assigned by S&P to debt
obligations in the High Yield Portfolio. These figures are dollar-weighted
averages of month-end portfolio holdings during the fiscal year ended December
31, 1996, presented as a percentage of total investments. These percentages are
historical and are not necessarily indicative of the quality of current or
future portfolio holdings, which may vary.
 
   
<TABLE>
<CAPTION>
      S&P
- ----------------
         AVERAGE
         PERCENT
           OF
         PORTFOLIO
RATING   HOLDINGS
- -------  -------
<S>      <C>
AAA      0.00%
         -------
AA       0.00%
         -------
A        0.21%
         -------
BBB      1.53%
         -------
BB       39.73%
         -------
B        37.48%
         -------
CCC      2.14%
         -------
CC       0.00%
         -------
Unrated  18.91%
         -------
</TABLE>
    
 
                       ADDITIONAL INVESTMENT INFORMATION
 
   
    DEPOSITARY RECEIPTS.  Each Portfolio, except the Global Fixed Income and
High Yield Portfolios, is permitted to invest in Depositary Receipts, including
American Depositary Receipts ("ADRs"), Global Depositary Receipts ("GDRs"),
European Depositary Receipts ("EDRs") and other Depositary Receipts (which,
together with ADRs, GDRs and EDRs, are hereinafter collectively referred to as
"Depositary Receipts"), to the extent that such Depositary Receipts are or
become available. ADRs are securities, typically issued by a U.S. financial
institution (a "depositary"), that evidence ownership interests in a security or
a pool of securities issued by a foreign issuer (the "underlying issuer") and
deposited with the depositary. ADRs include American Depositary Shares and New
York Shares and may be "sponsored" or "unsponsored." Sponsored ADRs are
established jointly by a depositary and the underlying issuer, whereas
unsponsored ADRs may be established by a depositary without participation by the
underlying issuer. The issuers of the stock of unsponsored ADRs are not
obligated to disclose material information in the United States and therefore,
there may not be a correlation between such information and the market value of
the ADR. GDRs, EDRs and other types of Depositary
    
 
                                       19
<PAGE>
Receipts are typically issued by foreign depositaries, although they may also be
issued by U.S. depositaries, and evidence ownership interests in a security or
pool of securities issued by either a foreign or a U.S. corporation. Generally,
Depositary Receipts in registered form are designed for use in the U.S.
securities market and Depositary Receipts in bearer form are designed for use in
securities markets outside the United States. The Portfolios may invest in
sponsored and unsponsored Depositary Receipts. For purposes of the Portfolios'
investment policies, the Portfolios' investments in Depositary Receipts will be
deemed to be investments in the underlying securities.
 
   
    FOREIGN CURRENCY FORWARD CONTRACTS.  Each Portfolio may enter into foreign
currency forward contracts ("forward contracts") that provide for the purchase
or sale of an amount of a specified currency at a future date. The Portfolios
may use such contracts to protect against a decline in a foreign currency
against the U.S. dollar between the trade date and settlement date when the
Portfolio purchases or sells securities, lock in the U.S. dollar value of
dividends and interest on securities held by the Portfolio, and generally to
protect the U.S. dollar value of securities held by the Portfolio against
exchange rate fluctuation. Forward contracts may also be used as a protective
measure against the effects of fluctuating rates of currency exchange and
exchange control regulations. While forward contracts may limit losses as a
result of exchange rate fluctuations, they will also limit any gains that might
otherwise have been realized. The Portfolio's Custodian may be required to place
cash or liquid securities in a segregated account in an amount equal to the
value of the Portfolio's total assets committed to the consummation of forward
contracts. If the value of the securities placed in the segregated account
declines, additional cash or securities will be placed in the account on a daily
basis so that the value of the account will be at least equal to the amount of
the Portfolio's commitments with respect to such contracts.
    
 
    FOREIGN INVESTMENT.  Investment in obligations of foreign issuers involves
somewhat different investment risks than those affecting obligations of U.S.
issuers. There may be limited publicly available information with respect to
foreign issuers, and foreign issuers are not generally subject to uniform
accounting, auditing and financial standards and requirements comparable to
those applicable to U.S. companies. There may also be less government
supervision and regulation of foreign securities exchanges, brokers and listed
companies than in the United States. Many foreign securities markets have
substantially less volume than U.S. national securities exchanges, and
securities of some foreign issuers are less liquid and more volatile than
securities of comparable domestic issuers. Brokerage commissions and other
transaction costs on foreign securities exchanges are generally higher than in
the United States. Dividends and interest paid by foreign issuers may be subject
to withholding and other foreign taxes, which may decrease the net return on
foreign investments as compared to dividends and interest paid to the Portfolios
by domestic companies, and it is not expected that a Portfolio or its
shareholders would be able to claim a credit for U.S. tax purposes with respect
to any such foreign taxes. Additional risks include future political and
economic developments, the possibility that a foreign jurisdiction might impose
or change withholding taxes on income payable with respect to foreign
securities, possible seizure, nationalization or expropriation of the foreign
issuer or foreign deposits and the possible adoption of foreign governmental
restrictions such as exchange controls. Also, it may be more difficult to obtain
a judgment in a court outside the United States.
 
    Investments in securities of foreign issuers are frequently denominated in
foreign currencies and the Portfolios may temporarily hold uninvested reserves
in bank deposits in foreign currencies. Therefore, the value of each Portfolio's
assets as measured in U.S. dollars may be affected favorably or unfavorably by
changes in currency rates and in exchange control regulations, and the
Portfolios may incur costs in connection with conversions between various
currencies.
 
                                       20
<PAGE>
   
    FUTURES CONTRACTS AND OPTIONS ON FUTURES CONTRACTS.  The Portfolios may
purchase and sell futures contracts and options on futures contracts, including
but not limited to financial futures, securities index futures, foreign currency
exchange futures, and interest rate futures contracts. Futures contracts provide
for the sale by one party and purchase by another party of a specified amount of
a specific security, instrument or basket thereof, at a specific future date and
at a specified price. An option on a futures contract is a legal contract that
gives the holder the right to buy or sell a specified amount of futures
contracts at a fixed or determinable price upon the exercise of the option.
    
 
   
    The Portfolios may sell securities index futures contracts and/or options
thereon in anticipation of or during a market decline to attempt to offset the
decrease in market value of investments in its portfolio, or purchase securities
index futures in order to gain market exposure. Subject to applicable laws, the
Portfolios may engage in transactions in securities index futures contracts (and
options thereon) which are traded on a recognized securities or futures
exchange, or may purchase or sell such instruments in the over-the-counter
market. There currently are limited securities index futures and options on such
futures in many countries, particularly emerging countries. The nature of the
strategies adopted by the Adviser, and the extent to which those strategies are
used, may depend on the development of such markets.
    
 
   
    The Portfolios may engage in transactions involving foreign currency
exchange futures contracts. Such contracts involve an obligation to purchase or
sell a specific currency at a specified future date and at a specified price.
The Portfolios may engage in such transactions to hedge their respective
holdings and commitments against changes in the level of future currency rates
or to gain exposure to a particular currency.
    
 
   
    The Portfolios may engage in transactions in interest rate futures
transactions. Interest rate futures contracts involve an obligation to purchase
or sell a specific debt security, instrument or basket thereof at a specified
future date at a specified price. The value of the contract rises and falls
inversely with changes in interest rates. The Portfolios may engage in such
transactions to hedge their holdings of debt instruments against future changes
in interest rates.
    
 
   
    Financial futures are futures contracts relating to financial instruments,
such as U.S. Government securities, foreign currencies, and certificates of
deposit. Such contracts involve an obligation to purchase or sell a specific
security, instrument or basket thereof at a specified future date at a specified
price. Like interest rate futures contracts, the value of financial futures
contracts rises and falls inversely with changes in interest rates. The
Portfolios may engage in financial futures contracts for hedging and non-hedging
purposes.
    
 
   
    Under rules adopted by the Commodity Futures Trading Commission, each
Portfolio may enter into futures contracts and options thereon for both hedging
and non-hedging purposes, provided that not more than 5% of such Portfolios'
total assets at the time of entering the transaction are required as margin and
option premiums to secure obligations under such contracts relating to
activities that do not constitute "bona-fide" hedging. No Portfolio, except the
Global Fixed Income Portfolio, will enter into futures contracts to the extent
that its outstanding obligations to purchase securities under such contracts, in
combination with its outstanding obligations with respect to options
transactions (including options to purchase securities or instruments) would
exceed 20% of its total assets.
    
 
   
    Gains and losses on futures contracts and options thereon depend on the
Adviser's ability to predict correctly the direction of securities prices,
interest rates and other economic factors. Other risks associated with the use
of futures and options are (i) imperfect correlation between the change in
market value of investments
    
 
                                       21
<PAGE>
   
held by a Portfolio and the prices of futures and options relating to
investments purchased or sold by the Portfolio, and (ii) possible lack of a
liquid secondary market for a futures contract and the resulting inability to
close a futures position. The risk that a Portfolio will be unable to close out
a futures position or options contract will be minimized by only entering into
futures contracts or options transactions for which there appears to be a liquid
exchange or secondary market. The risk of loss in trading on futures contracts
in some strategies can be substantial, due both to the low margin deposits
required and the extremely high degree of leverage involved in futures pricing.
    
 
    LOANS OF PORTFOLIO SECURITIES.  Each Portfolio may lend its securities to
brokers, dealers, domestic and foreign banks or other financial institutions for
the purpose of increasing its net investment income. These loans must be secured
continuously by cash or equivalent collateral, or by a letter of credit at least
equal to the market value of the securities loaned plus accrued interest or
income. There may be a risk of delay in recovery of the securities or even loss
of rights in the collateral should the borrower of the securities fail
financially. Each Portfolio will not enter into securities loan transactions
exceeding, in the aggregate, 33 1/3% of the market value of the Portfolio's
total assets. Securities lending entails certain risks of delay in recovery or
loss of rights in collateral in the event of the insolvency of the borrower.
 
   
    MONEY MARKET INSTRUMENTS.  Each Portfolio is permitted to invest in money
market instruments, although the Portfolios intend to stay invested in
securities satisfying their primary investment objective to the extent
practical. Each Portfolio may make money market investments pending other
investment or settlement for liquidity, or in adverse market conditions. See
"Temporary Investments." The money market investments permitted for the
Portfolios include: obligations of the U.S. Government and its agencies and
instrumentalities; other debt securities; commercial paper; bank obligations;
certificates of deposit (including Eurodollar certificates of deposit); and
repurchase agreements.
    
 
    NON-PUBLICLY TRADED SECURITIES, PRIVATE PLACEMENTS AND RESTRICTED
SECURITIES.  The High Yield Portfolio may invest in securities that are neither
listed on a stock exchange nor traded over-the-counter, including privately
placed securities. Such unlisted equity securities may involve a higher degree
of business and financial risk that can result in substantial losses. As a
result of the absence of a public trading market for these securities, they may
be less liquid than publicly traded securities. Although these securities may be
resold in privately negotiated transactions, the prices realized from these
sales could be less than those originally paid by the Portfolio or less than
what may be considered the fair value of such securities. Further, companies
whose securities are not publicly traded may not be subject to the disclosure
and other investor protection requirements which might be applicable if their
securities were publicly traded. If such securities are required to be
registered under the securities laws of one or more jurisdictions before being
resold, the Portfolio may be required to bear the expenses of registration.
 
    As a general matter, the Portfolio may not invest more than 15% of its net
assets in illiquid securities, including securities for which there is no
readily available secondary market. Nor as a general matter, may the Portfolio
invest more than 10% of its total assets in securities that are restricted from
sale to the public without registration ("Restricted Securities") under the
Securities Act of 1933, as amended (the "1933 Act"). However, the Portfolio may
invest up to 20% of its total assets in liquid Restricted Securities that can be
offered and sold to qualified institutional buyers under Rule 144A under the
1933 Act ("Rule 144A Securities"). The Board of Directors has adopted guidelines
and delegated to the Adviser, subject to the supervision of the Board of
Directors, the daily function of determining and monitoring the liquidity of
Rule 144A Securities. Rule 144A Securities may become illiquid if qualified
institutional buyers are not interested in acquiring the securities.
 
                                       22
<PAGE>
   
    OPTIONS TRANSACTIONS.  Each Portfolio, except the High Yield Portfolio, may
seek to increase its returns or may hedge its portfolio investments through
options transactions with respect to securities, instruments, indices or baskets
thereof in which such Portfolios may invest, as well as with respect to foreign
currency. Purchasing a put option gives a Portfolio the right to sell a
specified security, currency or basket of securities or currencies at the
exercise price until the expiration of the option. Purchasing a call option
gives a Portfolio the right to purchase a specified security, currency or basket
of securities or currencies at the exercise price until the expiration of the
option. A Portfolio may not purchase call and put options to the extent that the
value of its aggregate investment in options, excluding options on futures
contracts, exceeds 5% of its total assets.
    
 
   
    The Portfolios also may write (i.e., sell) put and call options on
investments held in its portfolio, as well as with respect to foreign currency.
A Portfolio that has written an option receives a premium, which increases the
Portfolio's return on the underlying security or instrument in the event the
option expires unexercised or is closed out at a profit. However, by writing a
call option, a Portfolio will limit its opportunity to profit from an increase
in the market value of the underlying security or instrument above the exercise
price of the option for as long as the Portfolio's obligation as writer of the
option continues. The Portfolios may only write options that are "covered." A
covered call option means that so long as the Portfolio is obligated as the
writer of the option, it will own (i) the underlying security or instrument
subject to the option or (ii) securities or instruments convertible or
exchangeable without the payment of any consideration into the security or
instrument subject to the option.
    
 
   
    By writing (or selling) a put option, a Portfolio incurs an obligation to
buy the security or instrument underlying the option from the purchaser of the
put at the option's exercise price at any time during the option period, at the
purchaser's election. Options written by a Portfolio may be exercisable by the
purchaser only on a specific date. A Portfolio that has written a put option
will earmark or segregate sufficient liquid assets to cover its obligations
under the option.
    
 
   
    The Portfolios may engage in transactions in options which are traded on
recognized exchanges or over-the-counter. There currently are limited options
markets in many countries, particularly emerging countries such as Latin
American countries, and the nature of the strategies adopted by the Adviser and
the extent to which those strategies are used will depend on the development of
such option markets. The primary risks associated with the use of options are
(i) imperfect correlation between the change in market value of investments
held, purchased or sold by a Portfolio and the prices of options relating to
such investments, and (ii) possible lack of a liquid secondary market for an
option.
    
 
   
    REPURCHASE AGREEMENTS.  Each Portfolio may enter into repurchase agreements
with brokers, dealers or banks that meet the credit guidelines established by
the Fund's Board of Directors. In a repurchase agreement, the Portfolio buys a
security from a seller that has agreed to repurchase it at a mutually agreed
upon date and price, reflecting the interest rate effective for the term of the
agreement. The term of these agreements is usually from overnight to one week,
and never exceeds one year. Repurchase agreements may be viewed as a fully
collateralized loan of money by the Portfolio to the seller. Each Portfolio
always receives securities with a market value at least equal to the purchase
price (including accrued interest) as collateral, and this value is maintained
during the term of the agreement. If the seller defaults and the collateral
value declines, the Portfolio might incur a loss. If bankruptcy proceedings are
commenced with respect to the seller, the Portfolio's realization upon the
collateral may be delayed or limited. The Portfolios may not enter into
repurchase agreements with more
    
 
                                       23
<PAGE>
than seven days to maturity if, as a result, more than 15% of the market value
of the Portfolio's net assets are invested in these agreements and other
investments for which market quotations are not readily available or which are
otherwise illiquid.
 
   
    TEMPORARY INVESTMENTS.  For temporary defensive purposes, when the Adviser
determines that market conditions warrant, each Portfolio may invest up to 100%
of its assets in dollar and non-dollar denominated money market instruments and
short- and medium-term debt securities that the Adviser believes to be of high
quality, or hold cash. The short- and medium-term debt securities in which a
Portfolio may invest consist of (a) obligations of the U.S. or foreign country
governments, their respective agencies or instrumentalities; (b) bank deposits
and bank obligations (including certificates of deposit, time deposits and
bankers' acceptances) of U.S. or foreign country banks denominated in any
currency; (c) floating rate securities and other instruments denominated in any
currency issued by international development agencies; (d) finance company and
corporate commercial paper and other short-term corporate debt obligations of
U.S. and foreign country corporations meeting the Portfolio's credit quality
standards; and (e) repurchase agreements with banks and broker-dealers with
respect to such securities.
    
 
    WHEN-ISSUED AND DELAYED DELIVERY SECURITIES.  Each Portfolio may purchase
securities on a when-issued or delayed delivery basis. In such transactions,
instruments are bought with payment and delivery taking place in the future in
order to secure what is considered to be an advantageous yield or price at the
time of the transaction. Delivery of and payment for these securities may take
as long as a month or more after the date of the purchase commitment, but will
take place no more than 120 days after the trade date. Each Portfolio will
maintain with the Custodian a separate account with a segregated portfolio of or
cash or liquid securities in an amount at least equal to these commitments. The
payment obligation and the interest rates that will be received are each fixed
at the time a Portfolio enters into the commitment and no interest accrues to
the Portfolio until settlement. Thus, it is possible that the market value at
the time of settlement could be higher or lower than the purchase price if the
general level of interest rates has changed. It is a current policy of each
Portfolio not to enter into when-issued commitments and delayed delivery
commitments exceeding in the aggregate 15% of the market value of the
Portfolio's total assets less liabilities other than the obligations created by
these commitments.
 
                             INVESTMENT LIMITATIONS
 
    As a diversified investment company, each Portfolio, except the Global Fixed
Income Portfolio, is subject to the following limitations: (a) as to 75% of its
total assets, a Portfolio may not invest more than 5% of its total assets in the
securities of any one issuer, except obligations of the United States Government
and its agencies and instrumentalities, and (b) a Portfolio may not own more
than 10% of the outstanding voting securities of any one issuer.
 
    The Global Fixed Income Portfolio is a non-diversified investment company
under the Investment Company Act of 1940, as amended (the "1940 Act"), which
means the Global Fixed Income Portfolio is not limited by the 1940 Act in the
proportion of its total assets that may be invested in the obligations of a
single issuer. Thus, the Global Fixed Income Portfolio may invest a greater
proportion of its total assets in the securities of a smaller number of issuers
and, as a result, will be subject to greater risk with respect to its portfolio
securities. Nevertheless, the Global Fixed Income Portfolio intends to comply
with the more limited diversification requirements imposed by the Internal
Revenue Code of 1986, as amended (the "Code"), for qualification as a regulated
investment company.
 
                                       24
<PAGE>
    Each Portfolio also operates under certain investment restrictions that are
deemed fundamental limitations and may be changed only with the approval of the
holders of a majority of such Portfolio's outstanding shares and under certain
non-fundamental investment limitations that may be changed without shareholder
approval. For additional information on fundamental and non-fundamental
investment limitations, see "Investment Limitations" in the Statement of
Additional Information.
 
                             MANAGEMENT OF THE FUND
 
    INVESTMENT ADVISER.  Morgan Stanley Asset Management Inc. is the Adviser and
Administrator of the Fund and each Portfolio. The Adviser provides investment
advice and portfolio management services, pursuant to an Investment Advisory
Agreement and, subject to the supervision of the Fund's Board of Directors,
makes each Portfolio's day-to-day investment decisions, arranges for the
execution of portfolio transactions and generally manages each Portfolio's
investments. Set forth below as an annual percentage of average daily net assets
are the management fees payable to the Adviser quarterly by each Portfolio
pursuant to the terms of the Investment Advisory Agreement. The Adviser has
agreed to a reduction in the fees payable to it and to reimburse the Portfolios,
if necessary, if such fees would cause total annual operating expenses of the
Portfolios to exceed the maximums set forth in the table below.
 
   
<TABLE>
<CAPTION>
                                                      MAXIMUM TOTAL OPERATING
                                                              EXPENSES
                                                         AFTER FEE WAIVERS
                                       MANAGEMENT   ----------------------------
             PORTFOLIO                    FEE          CLASS A        CLASS B
- ------------------------------------  ------------  -------------  -------------
<S>                                   <C>           <C>            <C>
Small Cap Value Equity Portfolio            0.85%         1.00%          1.25%
Value Equity Portfolio                      0.50%         0.70%          0.95%
Balanced Portfolio                          0.50%         0.70%          0.95%
Global Fixed Income                         0.40%         0.50%          0.65%
High Yield                                 0.375%         0.75%          1.00%
</TABLE>
    
 
   
    The Adviser, with principal offices at 1221 Avenue of the Americas, New
York, New York 10020, conducts a worldwide portfolio management business and
provides a broad range of portfolio management services to customers in the
United States and abroad. On February 5, 1997, Morgan Stanley Group Inc. and
Dean Witter, Discover & Co. announced that they had entered into an Agreement
and Plan of Merger to form Morgan Stanley, Dean Witter, Discover & Co. Morgan
Stanley Group Inc. is the direct parent of the Adviser and Morgan Stanley.
Subject to certain conditions being met, it is currently anticipated that the
transaction will close in mid-1997. Thereafter, the Adviser and Morgan Stanley
will be subsidiaries of Morgan Stanley, Dean Witter, Discover & Co. At March 31,
1997, the Adviser, together with its affiliated asset management companies,
managed investments totaling in excess of $118 billion, including approximately
$100 billion under active management and $18 billion as Named Fiduciary or
Fiduciary Adviser. See "Management of the Fund" in the Statement of Additional
Information.
    
 
PORTFOLIO MANAGERS. The following individuals have primary portfolio management
responsibility for the Portfolios noted below:
 
   
    SMALL CAP VALUE EQUITY PORTFOLIO -- CHRISTIAN K. STADLINGER.  Mr. Stadlinger
is a Vice President of the Adviser and manages the small-cap value equity
product of the Adviser's Chicago affiliate. He became a member
    
 
                                       25
<PAGE>
   
of the Adviser's Chicago large cap value portfolio management team, specializing
in quantitative and fundamental research, upon completion of his doctoral
dissertation at Northwestern University in April 1989. Mr. Stadlinger was the
catalyst in the development of the Adviser's small-cap value product, and he
continues to research and develop structured valuation techniques in the area of
small cap investing. Mr. Stadlinger has a degree in Computer Science and
Economics from the University of Vienna, a Ph.D. in Economics from Northwestern
University, and is a Certified Financial Analyst.
    
 
   
    VALUE EQUITY AND BALANCED PORTFOLIOS -- STEPHEN C. SEXAUER AND ALFORD E.
ZICK, JR.  Mr. Sexauer is a Principal of Morgan Stanley and is a member of the
investment management team of the Adviser's Chicago affiliate as well as Vice
President of the Adviser. In addition to portfolio management, his equity
research responsibilities include aerospace, industrials, capital goods,
transportation, and diversified financial companies. Mr. Sexauer joined the firm
in July 1989 after three years as a Vice President at Salomon Brothers.
Previously, he was with Merrill Lynch Economics and Wharton Econometrics. Mr.
Sexauer received a B.S. in Economics from the University of Illinois and an
M.B.A. in Economics and Statistics from the University of Chicago. Mr. Zick is a
Principal of Morgan Stanley and is a member of the investment management team of
the Adviser's Chicago affiliate. In addition to portfolio management, his equity
research responsibilities include consumer staples, retail and insurance
companies. He became a member of the Adviser's Chicago investment management
team in August 1989, after an extensive career in asset management with Chicago
Pacific Corporation, Staley Continental, Inc., and A.E. STALEY Manufacturing
Company. Mr. Zick has a degree in accounting from the University of Illinois.
Mr. Sexauer and Mr. Zick have had primary responsibility for managing the Value
Equity and Balanced Portfolios since their inception in January and February,
1990, respectively.
    
 
   
    GLOBAL FIXED INCOME PORTFOLIO -- J. DAVID GERMANY, MICHAEL B. KUSHMA, PAUL
F. O'BRIEN AND ROBERT M. SMITH. J. David Germany shares primary responsibility
for managing the Portfolio's assets. He joined the Adviser in 1996 and has been
a portfolio manager with the Adviser's affiliate, Miller Anderson & Sherrerd,
LLP ("MAS") since 1991. He was Vice President & Senior Economist for Morgan
Stanley from 1989 to 1991. He assumed responsibility for the Global Fixed Income
and International Fixed Income Portfolios of the MAS-advised MAS Funds in 1993
and the MAS Fund's Multi-Asset-Class Portfolio in 1994. Mr. Germany was Senior
Staff Economist (International Finance and Macroeconomics) to the Council of
Economic Advisors -- Executive Office of the President from 1986 through 1987
and an Economist with the Board of Governors of the Federal Reserve System --
Division of International Finance from 1983 through 1987. He holds an A.B.
degree (Valedictorian) from Princeton University and a Ph.D. in Economics from
the Massachusetts Institute of Technology. Michael B. Kushma, a Principal at
Morgan Stanley, joined the firm in 1987. He shares primary responsibility for
managing the Portfolio's assets. He was a member of Morgan Stanley's Global
fixed income strategy group in the fixed income division from 1987-1995 where he
became the divisions' senior government bond strategist. He joined the Adviser
in 1995 where he took responsibility for the global fixed income portfolios. Mr.
Kushma received an A.B. in economics from Princeton University in 1979, and M.
Sc. in economics from the London School of Economics in 1981 and an M.Phil. in
economics from Columbia University in 1983. Paul F. O'Brien shares primary
responsibility for managing the Portfolio's assets. He joined the Adviser and
MAS in 1996. He was head of European Economics from 1993 through 1995 for JP
Morgan and as Principal Administrator from 1991 through 1992 for the
Organization for Economic Cooperation and Development. He assumed responsibility
for the MAS-advised MAS Funds' Global Fixed Income and International Fixed
Income Portfolios in 1996. Mr. O'Brien holds a B.S. degree from the
Massachusetts Institute of Technology and a Ph.D. in Economics from the
University of Minnesota. Robert Smith, a Principal of Morgan
    
 
                                       26
<PAGE>
Stanley, joined the Adviser in June 1994 and has shared primary responsibility
for managing the Portfolio's assets since July 1994. Prior to joining the
Adviser he spent eight years as Senior Portfolio Manager -- Fixed Income at the
State of Florida Pension Fund. Mr. Smith's responsibilities included active
total-rate-of-return management of long term portfolios and supervision of other
fixed income managers. A graduate of Florida State University with a B.S. in
Business, Mr. Smith also received an M.B.A. -- Finance from Florida State and
holds a Chartered Financial Analyst (CFA) designation.
 
    HIGH YIELD PORTFOLIO -- ROBERT ANGEVINE, THOMAS L. BENNETT AND STEPHEN F.
ESSER. ROBERT ANGEVINE is a Principal of the Adviser and the Portfolio Manager
for high yield investments. He shares primary responsibility for managing the
Portfolio's assets. Prior to joining the Adviser in October 1988, he spent over
eight years at Prudential Insurance where he was responsible for the largest
open-end high yield mutual fund in the country. Mr. Angevine also manages high
yield assets for one of the largest corporate pension funds in the country. His
other experience includes international treasury operations at a major
pharmaceutical company and commercial banking. Mr. Angevine received an M.B.A
from Fairleigh Dickinson University and a B.A. in Economics from Lafayette
College. He served two years as a Lieutenant in the U.S. Army. Thomas L. Bennett
shares responsibility for managing the Portfolio's assets. He joined the Adviser
in 1996 and has been a portfolio manager with MAS since 1984. Mr. Bennett
assumed responsibility for the MAS-advised MAS Funds' Fixed Income Portfolio in
1984, the Domestic Fixed Income Portfolio in 1987, the High Yield Portfolio in
1985, the Fixed Income Portfolio II in 1990, the Special Purpose Fixed Income
and Balanced Portfolios in 1992 and the Multi-Asset-Class Portfolio in 1994. Mr.
Bennett also is the Chairman of the MAS Funds and has a B.S degree (Chemistry)
and an M.B.A. from the University of Cincinnati. Stephen F. Esser shares primary
responsibility for managing the Portfolio's assets. He joined the Adviser in
1996 and has been a portfolio manager with MAS since 1988. He assumed
responsibility for the MAS-advised MAS Funds' High Yield Portfolio in 1989. Mr.
Esser is a member of the New York Society of Security Analysts and has a B.S.
degree (Summa Cum Laude; Phi Beta Kappa) from the University of Delaware.
 
    ADMINISTRATOR.  The Adviser also provides administrative services to the
Fund pursuant to an Administration Agreement. The services provided under the
Administration Agreement are subject to the supervision of the Officers and the
Board of Directors of the Fund and include day-to-day administration of matters
related to the corporate existence of the Fund, maintenance of its records,
preparation of reports, supervision of the Fund's arrangements with its
custodian, and assistance in the preparation of the Fund's registration
statements under federal laws. The Administration Agreement also provides that
the Administrator, through its agents, will provide dividend disbursing and
transfer agent services to the Fund. For its services under the Administration
Agreement, the Fund pays the Adviser a monthly fee which on an annual basis
equals 0.15% of the average daily net assets of each Portfolio.
 
   
    Under an agreement between the Adviser and The Chase Manhattan Bank
("Chase"), Chase provides certain administrative services to the Fund through
its corporate affiliate, Chase Global Funds Services Company ("CGFSC"). The
Adviser supervises and monitors such administrative services provided by CGFSC.
Their services are also subject to the supervision of the Board of Directors of
the Fund. CGFSC's business address is 73 Tremont Street, Boston, Massachusetts
02108-3913.
    
 
    DIRECTORS AND OFFICERS.  Pursuant to the Fund's Articles of Incorporation,
the Board of Directors decides upon matters of general policy and reviews the
actions of the Fund's Adviser, Administrator, Distributor and other service
providers. The Officers of the Fund conduct and supervise its daily business
operations.
 
                                       27
<PAGE>
    DISTRIBUTOR.  Morgan Stanley serves as the exclusive Distributor of the
shares of the Fund. Under its Distribution Agreement with the Fund, Morgan
Stanley sells shares of each Portfolio upon the terms and at the current
offering price described in this Prospectus. Morgan Stanley is not obligated to
sell any certain number of shares of any Portfolio.
 
    The Portfolios currently offer only the classes of shares offered by this
Prospectus. The Portfolios may in the future offer one or more classes of shares
with features, distribution expenses or other expenses that are different from
those of the classes currently offered.
 
    The Fund has adopted a Plan of Distribution with respect to the Class B
shares of each Portfolio pursuant to Rule 12b-1 under the 1940 Act (each, a
"Plan"). Under each Plan, the Distributor is entitled to receive from each
Portfolio a distribution fee, which is accrued daily and paid quarterly, of
0.25% of the Class B shares' average daily net assets on an annualized basis.
The Distributor expects to reallocate most of its fee to its investment
representatives. The Distributor may, in its discretion, voluntarily waive from
time to time all or any portion of its distribution fee and each of the
Distributor and the Adviser is free to make additional payments out of its own
assets to promote the sale of Fund shares, including payments that compensate
financial institutions for distribution services or shareholder services.
 
   
    Each Plan is designed to compensate the Distributor for its services, not to
reimburse the Distributor for its expenses, and the Distributor may retain any
portion of the fee that it does not expend in fulfillment of its obligations to
the Fund. The Distributor has agreed to waive 0.10% of the 0.25% distribution
fee it is entitled to receive from the Global Fixed Income Portfolio.
    
 
    EXPENSES.  Each Portfolio is responsible for payment of certain other fees
and expenses (including legal fees, accountant's fees, custodial fees and
printing and mailing costs) specified in the Administration and Distribution
Agreements.
 
                               PURCHASE OF SHARES
 
    Class A and Class B shares of each Portfolio may be purchased at the net
asset value per share next determined after receipt of the purchase order by the
Portfolios. See "Valuation of Shares."
 
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
 
    For a Portfolio account opened on or after January 2, 1996 (a "New
Account"), the minimum initial investment and minimum account size are $500,000
for Class A shares and $100,000 for Class B shares of each Portfolio. Certain
advisory or asset allocation accounts, such as Total Funds Management accounts,
managed by Morgan Stanley or its affiliates, including the Adviser ("Managed
Accounts") may purchase Class A shares without being subject to a minimum
initial investment or minimum account size requirements for a Portfolio account.
Employees of the Adviser and certain of its affiliates may purchase Class A
shares subject to conditions, including a lower minimum initial investment,
established by Officers of the Fund.
 
    If the value of a New Account containing Class A shares falls below $500,000
(but remains at or above $100,000) because of shareholder redemption(s), the
Fund will notify the shareholder, and if the account value remains below
$500,000 (but remains at or above $100,000) for a continuous 60-day period, the
Class A shares in such account will convert to Class B shares and will be
subject to the distribution fee and other features
 
                                       28
<PAGE>
applicable to the Class B shares. The Fund, however, will not convert Class A
shares to Class B shares based solely upon changes in the market that reduce the
net asset value of shares. Under current tax law, conversions between share
classes are not a taxable event to the shareholder.
 
    Shares in a Portfolio account opened prior to January 2, 1996 (a "Pre-1996
Account") were designated Class A shares on January 2, 1996. Shares in a
Pre-1996 Account with a value of $100,000 or more on March 1, 1996 (a
"Grandfathered Class A Account") remained Class A shares regardless of account
size thereafter. Except for shares in a Managed Account, shares in a Pre-1996
Account with a value of less than $100,000 on March 1, 1996 (a "Grandfathered
Class B Account") converted to Class B shares on March 1, 1996. Grandfathered
Class A Accounts and Managed Accounts are not subject to conversion from Class A
shares to Class B shares.
 
    Investors may also invest in the Fund by purchasing shares through a trust
department, broker, dealer, agent, financial planner, financial services firm or
investment adviser. An investor may be charged an additional service or
transaction fee by that institution.
 
   
    The minimum investment levels may be waived at the discretion of the Adviser
for (i) certain employees and customers of Morgan Stanley or its affiliates and
certain trust departments, brokers, dealers, agents, financial planners,
financial services firms, or investment advisers that have entered into an
agreement with Morgan Stanley or its affiliates; and (ii) retirement and
deferred compensation plans and trusts used to fund such plans, including, but
not limited to, those defined in Section 401(a), 403(b) or 457 of the Code and
"rabbi trusts". The Fund reserves the right to modify or terminate the
conversion features of the shares as stated above at any time upon 60-days
notice to shareholders.
    
 
    The Adviser reserves the right in its sole discretion to determine which of
such advisory or asset allocation accounts shall be Managed Accounts. For
information regarding Managed Accounts, please contact your Morgan Stanley
account representative or the Fund at the telephone number provided on the cover
of this Prospectus.
 
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
 
    If the value of a New Account falls below $100,000 because of shareholder
redemption(s), the Fund will notify the shareholder, and if the account value
remains below $100,000 for a continuous 60-day period, the shares in such
account are subject to redemption by the Fund and, if redeemed, the net asset
value of such shares will be promptly paid to the shareholder. The Fund,
however, will not redeem shares based solely upon changes in the market that
reduce the net asset value of shares.
 
    Grandfathered Class A Accounts, Grandfathered Class B Accounts and Managed
Accounts are not subject to involuntary redemption. The Fund reserves the right
to modify or terminate the involuntary redemption features of the shares as
stated above at any time upon 60-days notice to shareholders.
 
CONVERSION FROM CLASS B TO CLASS A SHARES
 
    If the value of Class B shares in a Portfolio account increases, whether due
to shareholder share purchases or market activity, to $500,000 or more, the
Class B shares will convert to Class A shares. Under current tax law, such
conversion is not a taxable event to the shareholder. Class A shares converted
from Class B shares are subject to the same minimum account size requirements
that are applicable to New Accounts containing Class A shares, as stated above.
The Fund reserves the right to modify or terminate this conversion feature at
any time upon 60-days notice to shareholders.
 
                                       29
<PAGE>
INITIAL PURCHASES DIRECTLY FROM THE FUND
 
    The Fund's determination of an investor's eligibility to purchase shares of
a given class will take precedence over the investor's selection of a class.
Assuming the investor is eligible for the class, the Fund will select the most
favorable class for the investor, if the investor has not done so.
 
1) BY CHECK.  An account may be opened by completing and signing an Account
   Registration Form and mailing it, together with a check ($500,000 minimum for
   Class A shares of each Portfolio and $100,000 minimum for Class B shares of
   each Portfolio, with certain exceptions for Morgan Stanley employees and
   select customers) payable to "Morgan Stanley Institutional Fund, Inc. --
   [portfolio name]," to:
 
      Morgan Stanley Institutional Fund, Inc.
      P.O. Box 2798
      Boston, Massachusetts 02208-2798
 
    Payment will be accepted only in U.S. dollars, unless prior approval for
  payment in other currencies is given by the Fund. The Portfolio(s) to be
  purchased should be designated on the Account Registration Form. For purchases
  by check, the Fund is ordinarily credited with Federal Funds within one
  business day. Thus, your purchase of shares by check is ordinarily credited to
  your account at the net asset value per share of the relevant Portfolio
  determined on the next business day after receipt.
 
2) BY FEDERAL FUNDS WIRE.  Purchases may be made by having your bank wire
   Federal Funds to the Fund's bank account. In order to ensure prompt receipt
   of your Federal Funds Wire, it is important that you follow these steps:
 
A.  Telephone the Fund (toll free: 1-800-548-7786) and provide us with your
    name, address, telephone number, Social Security or Tax Identification
    Number, the portfolio(s) selected, the class selected, the amount being
    wired, and by which bank. We will then provide you with a Fund account
    number. (Investors with existing accounts should also notify the Fund prior
    to wiring funds.)
 
B.  Instruct your bank to wire the specified amount to the Fund's Wire
    Concentration Bank Account (be sure to have your bank include the name of
    the portfolio(s) selected, the class selected and the account number
    assigned to you) as follows:
 
   
    The Chase Manhattan Bank
    One Manhattan Plaza
    New York, NY 10081-1000
    ABA #021000021
    DDA #910-2-733293
    Attn: Morgan Stanley Institutional Fund, Inc.
    Ref: (Portfolio name, your account number, your account name)
    
 
    Please call the Fund at 1-800-548-7786 prior to wiring funds.
 
C.  Complete and sign the Account Registration Form and mail it to the address
    shown thereon.
 
   
  The purchase price of the Class A and Class B shares of each Portfolio is the
  net asset value next determined after the order is received. See "Valuation of
  Shares." An order received prior to the close of the New York
    
 
                                       30
<PAGE>
  Stock Exchange ("NYSE"), which is currently 4:00 p.m. Eastern Time, will be
  executed at the price computed on the date of receipt; an order received after
  the regular close of the NYSE will be executed at the price computed the next
  day the NYSE is open as long as the Transfer Agent receives payment by check
  or in Federal Funds prior to the regular close of the NYSE on such day.
 
  Federal Funds purchase orders will be accepted only on a day on which the Fund
  and Chase (the "Custodian Bank") are open for business. Your bank may charge a
  service fee for wiring Federal Funds.
 
3) BY BANK WIRE.  The same procedure outlined under "By Federal Funds Wire"
   above must be followed in purchasing shares by bank wire. However, money
   transferred by bank wire may or may not be converted into Federal Funds the
   same day, depending on the time the money is received and the bank handling
   the wire. Prior to such conversion, an investor's money will not be invested
   and, therefore, will not be earning dividends. Your bank may charge a service
   fee for wiring funds.
 
ADDITIONAL INVESTMENTS
 
    You may add to your account at any time (minimum additional investment
$1,000 for each Portfolio, except for automatic reinvestment of dividends and
capital gains distributions for which there are no minimums) by purchasing
shares at net asset value by mailing a check to the Fund (payable to "Morgan
Stanley Institutional Fund, Inc. -- [portfolio name]") at the above address or
by wiring monies to the Custodian Bank as outlined above. It is very important
that your account name, the portfolio name and the class selected be specified
in the letter or wire to assure proper crediting to your account. In order to
help to ensure that your wire orders are invested promptly, you are requested to
notify one of the Fund's representatives (toll free 1-800-548-7786) prior to the
wire date. Additional investments will be applied to purchase additional shares
in the same class held by a shareholder in a Portfolio account.
 
OTHER PURCHASE INFORMATION
 
    Although the legal rights of Class A and Class B shares will be identical,
the different expenses borne by each class will result in different net asset
values and dividends. The net asset value of Class B shares will generally be
lower than the net asset value of Class A shares as a result of the distribution
expense charged to Class B shares. It is expected, however, that the net asset
value per share of the two classes will tend to converge immediately after the
recording of dividends which will differ by approximately the amount of the
distribution expense accrual differential between the classes.
 
    In the interest of economy and convenience, and because of the operating
procedures of the Fund, certificates representing shares of the Portfolios will
not be issued. All shares purchased are confirmed to you and credited to your
account on the Fund's books maintained by the Adviser or its agents. You will
have the same rights and ownership with respect to such shares as if
certificates had been issued.
 
    To ensure that checks are collected by the Fund, withdrawals of investments
made by check are not presently permitted until payment for the purchase has
been received, which may take up to eight business days after the date of
purchase. As a condition of this offering, if a purchase is cancelled due to
nonpayment or because your check does not clear, you will be responsible for any
loss the Fund or its agents incur. If you are already a shareholder, the Fund
may redeem shares from your account(s) to reimburse the Fund or its agents for
any loss. In addition, you may be prohibited or restricted from making future
investments in the Fund.
 
                                       31
<PAGE>
    Investors may also invest in the Fund by purchasing shares through the
Distributor.
 
EXCESSIVE TRADING
 
   
    Frequent trades involving either substantial portfolio assets or a
substantial portion of your account or accounts controlled by you can disrupt
management of a portfolio and raise its expenses. Consequently, in the interest
of all the stockholders of each Portfolio and each Portfolio's performance, the
Fund may in its discretion bar a stockholder that engages in excessive trading
of shares of any class of a portfolio from further purchases of shares of the
Fund for an indefinite period. The Fund considers excessive trading to be more
than one purchase and sale involving shares of the same class of a portfolio of
the Fund within any 120-day period. As an example, exchanging shares of
portfolios of the Fund as follows amounts to excessive trading: exchanging
shares of Portfolio A for shares of Portfolio B, then exchanging shares of
Portfolio B for shares of Portfolio C and again exchanging shares of Portfolio C
for shares of Portfolio B within a 120-day period. Two types of transactions are
exempt from these excessive trading restrictions: (1) trades exclusively between
money market portfolios; and (2) trades done in connection with an asset
allocation service, such as TFM Accounts, managed or advised by the Adviser
and/or any of its affiliates.
    
 
INVESTMENT IN FUNDS THROUGH A TOTAL FUNDS MANAGEMENT ("TFM") ACCOUNT
 
   
    In addition to the considerable diversification among individual securities
you receive by investing in a particular Portfolio, you can further reduce risk
by spreading your assets among several different Portfolios that each have
different risk and return characteristics. TFM is an active investment
management service managed by Morgan Stanley or its affiliates, including Morgan
Stanley Asset Management Inc. (each, a "TFM Adviser"), that allocates your
investments across a combination of either Class A or Class B shares of certain
of the Portfolios selected to meet your long-term investment objectives as well
as, in certain circumstances, your current income objectives.
    
 
   
    The TFM Adviser has developed investment strategies for TFM Accounts to meet
the diverse financial needs of different investors. You can open a TFM Account
by meeting with one of the investment professionals of a Participating Dealer
who will review your situation and help you identify your long-term investment
and/or current income objectives. After using TFM criteria to determine your
long-term investment and/or current income objectives, you can choose one of
several TFM investment strategies. Based on your chosen strategy, your initial
investment will be allocated among a number of the Class A or Class B shares of
the Portfolios. Depending on market conditions, the TFM Adviser periodically
reallocates the combination of Portfolios or the percentage amounts invested in
the shares of each Portfolio to implement your TFM investment strategy. In
addition, your TFM Account will be periodically rebalanced to maintain your TFM
strategy's current asset allocation mix, if and when the performance of one or
more of the Portfolios unbalances the strategy's mix. You will pay the TFM
Adviser a fee for the TFM Account service that is in addition to and separate
from the fees and expenses you will pay directly or indirectly as an investor in
the Portfolios. See "Fund Expenses."
    
 
    From time to time, one or more of the Portfolios used for investment by the
TFM Accounts may experience relatively large investments or redemptions due to
the TFM Account allocations or rebalancings recommended by the TFM Adviser.
These transactions will affect the Portfolios, since Portfolios that experience
redemptions as a result of reallocations or rebalancings may have to sell
portfolio securities and Portfolios that receive additional cash will have to
invest it in additional portfolio securities. While it is impossible to predict
the overall impact of these transactions over time, there could be adverse
effects on portfolio management to the extent that Portfolios
 
                                       32
<PAGE>
   
may be required to sell securities or invest cash at times when they would not
otherwise do so. These transactions could also have tax consequences if sales of
securities resulted in gains and could also increase transaction costs. The
Adviser, representing the interests of the Portfolios, is committed to
minimizing the impact of TFM Account transactions on the Portfolios. The
Adviser, however, will have a conflict in fulfilling this responsibility in that
it also serves as a TFM Adviser. In that capacity, the Adviser, representing the
interests of the TFM Accounts, also is committed to minimizing the impact of TFM
Account transactions on the Portfolios to the extent consistent with pursuing
the investment objectives of the TFM Accounts. In addition, an affiliate of the
TFM Adviser, the Distributor is compensated on the sale, and may be compensated
for distribution or shareholder services on the sale of shares of the
Portfolios. See "Purchase of Shares" and "Shareholder Services -- Exchange
Features." The Adviser will monitor the impact of TFM Account transactions on
the Portfolios.
    
 
                              REDEMPTION OF SHARES
 
    You may withdraw all or any portion of the amount in your account by
redeeming shares at any time. Please note that purchases made by check are not
permitted to be redeemed until payment of the purchase price has been collected,
which may take up to eight business days after purchase. The Fund will redeem
Class A shares or Class B shares of each Portfolio at the next determined net
asset value of shares of their applicable class. On days that both the NYSE and
the Custodian Bank are open for business, the net asset value per share of each
of the Portfolios is determined at the regular close of trading of the NYSE
(currently 4:00 p.m. Eastern Time). Shares of each Portfolio may be redeemed by
mail or telephone. No charge is made for redemption. Any redemption proceeds may
be more or less than the purchase price of your shares depending on, among other
factors, the market value of the investment securities held by a Portfolio.
 
BY MAIL
 
    Each Portfolio will redeem its Class A or Class B shares at the net asset
value determined on the date the request is received, if the request is received
in "good order" before the regular close of the NYSE. Your request should be
addressed to Morgan Stanley Institutional Fund, Inc., P.O. Box 2798, Boston,
Massachusetts 02208-2798, except that deliveries by overnight courier should be
addressed to Morgan Stanley Institutional Fund, Inc., c/o Chase Global Funds
Services Company, 73 Tremont Street, Boston, Massachusetts 02108-3913.
 
    "Good order" means that the request to redeem shares must include the
following documentation:
 
        (a)  A letter of instruction or a stock assignment specifying the class
    and number of shares or dollar amount to be redeemed, signed by all
    registered owners of the shares in the exact names in which they are
    registered;
 
        (b) Any required signature guarantees (see "Further Redemption
    Information" below); and
 
        (c)  Other supporting legal documents, if required, in the case of
    estates, trusts, guardianships, custodianships, corporations, pension and
    profit-sharing plans and other organizations.
 
    Shareholders who are uncertain of requirements for redemption should consult
with a Fund representative.
 
                                       33
<PAGE>
BY TELEPHONE
 
   
    Provided you have previously elected the Telephone Redemption Option on the
Account Registration Form, you can request a redemption of your shares by
calling the Fund and requesting the redemption proceeds be mailed to you or
wired to your bank. Please contact one of the Fund's representatives for further
details. In times of drastic market conditions, the telephone redemption option
may be difficult to implement. If you experience difficulty in making a
telephone redemption, your request may be made by regular mail or express mail
and it will be implemented at the net asset value next determined after it is
received. Redemption requests sent to the Fund through express mail must be
mailed to the address of the Dividend Disbursing and Transfer Agent listed under
"General Information." The Fund and the Transfer Agent will employ reasonable
procedures to confirm that instructions communicated by telephone are genuine.
These procedures include requiring the investor to provide certain personal
identification information at the time an account is opened and prior to
effecting each transaction requested by telephone. In addition, all telephone
transaction requests will be recorded and investors may be required to provide
additional telecopied written instructions regarding transaction requests.
Neither the Fund nor the Transfer Agent will be responsible for any loss,
liability, cost or expense for following instructions received by telephone that
either of them reasonably believes to be genuine.
    
 
    To change the commercial bank or account designated to receive redemption
proceeds, a written request must be sent to the Fund at the address above.
Requests to change the bank or account must be signed by each shareholder and
each signature must be guaranteed.
 
FURTHER REDEMPTION INFORMATION
 
    Normally the Fund will make payment for all shares redeemed within one
business day of receipt of the request, but in no event will payment be made
more than seven days after receipt of a redemption request in good order.
However, payments to investors redeeming shares which were purchased by check
will not be made until payment for the purchase has been collected, which may
take up to eight days after the date of purchase. The Fund may suspend the right
of redemption or postpone the date upon which redemptions are effected at times
when the NYSE is closed, or under any emergency circumstances as determined by
the Securities and Exchange Commission (the "Commission").
 
    If the Board of Directors determines that it would be detrimental to the
best interests of the remaining shareholders of a Portfolio to make payment
wholly or partly in cash, the Fund may pay the redemption proceeds in whole or
in part by a distribution in-kind of securities held by a Portfolio in lieu of
cash in conformity with applicable rules of the Commission.
Distributions-in-kind will be made in readily marketable securities. Investors
may incur brokerage charges on the sale of portfolio securities so received in
payment of redemptions.
 
    To protect your account, the Fund and its agents from fraud, signature
guarantees are required for certain redemptions to verify the identity of the
person who has authorized a redemption from your account. Please contact the
Fund for further information. See "Redemption of Shares" in the Statement of
Additional Information.
 
                                       34
<PAGE>
                              SHAREHOLDER SERVICES
 
EXCHANGE FEATURES
 
    You may exchange shares that you own in any Portfolio for shares of any
other available portfolio(s) of the Fund (other than the International Equity
Portfolio, which is closed to new investors). In exchanging for shares of a
portfolio with more than one class, the class of shares you receive in the
exchange will be determined in the same manner as any other purchase of shares
and will not be based on the class of shares surrendered for the exchange.
Consequently, the same minimum initial investment and minimum account size for
determining the class of shares received in the exchange will apply. See
"Purchase of Shares." Shares of the portfolios may be exchanged by mail or
telephone. The privilege to exchange shares by telephone is automatic and made
available without shareholder election. Before you make an exchange, you should
read the prospectus of the portfolio(s) in which you seek to invest. Because an
exchange transaction is treated as a redemption followed by a purchase, an
exchange would be considered a taxable event for shareholders subject to tax.
The exchange privilege may be modified or terminated by the Fund at any time
upon 60-days notice to shareholders.
 
BY MAIL
 
    In order to exchange shares by mail, you should include in the exchange
request the name, class of shares and account number of your current Portfolio,
the names(s) of the portfolio(s) and class(es) of shares into which you intend
to exchange shares, and the signatures of all registered account holders. Send
the exchange request to Morgan Stanley Institutional Fund, Inc., P.O. Box 2798,
Boston, Massachusetts 02208-2798.
 
BY TELEPHONE
 
   
    When exchanging shares by telephone, have ready the name, class of shares
and account number of the current Portfolio, the name(s) of the portfolio(s) and
class(es) of shares into which you intend to exchange shares, your Social
Security number or Tax I.D. number, and your account address. Requests for
telephone exchanges received prior to 4:00 p.m. (Eastern Time) are processed at
the close of business that same day based on the net asset value of the class of
the portfolios involved in the exchange of shares at the close of business.
Requests received after 4:00 p.m. are processed the next business day based on
the net asset value determined at the close of business on such day. For
additional information regarding responsibility for the authenticity of
telephoned instructions, see "Redemption of Shares -- By Telephone" above.
    
 
TRANSFER OF REGISTRATION
 
    You may transfer the registration of any of your Portfolio shares to another
person by writing to Morgan Stanley Institutional Fund, Inc., P.O. Box 2798,
Boston, Massachusetts 02208-2798. As in the case of redemptions, the written
request must be received in good order before any transfer can be made.
Transferring the registration of shares may affect the eligibility of your
account for a given class of the Portfolio's shares and may result in
involuntary conversion or redemption of your shares. See "Purchase of Shares"
above.
 
                              VALUATION OF SHARES
 
    The net asset value per share of a class of shares of each of the Portfolios
is determined by dividing the total market value of the Portfolio's investments
and other assets attributable to such a class, less any liabilities attributable
to such a class, by the total number of outstanding shares of each class of the
Portfolio. Net asset value is calculated separately for each class of the
Portfolio. Net asset value per share is determined as of the
 
                                       35
<PAGE>
   
regular close of the NYSE on each day that the NYSE is open for business. Price
information on listed securities is taken from the exchange where the security
is primarily traded. Securities listed on a U.S. securities exchange for which
market quotations are available are valued at the last quoted sale price on the
day the valuation is made. Securities listed on a foreign exchange are valued at
their closing price. Unlisted securities and listed securities not traded on the
valuation date for which market quotations are readily available are valued at a
price within a range not exceeding the current asked price nor less than the
current bid price. The current bid and asked prices are determined based on the
average bid and asked prices quoted on such valuation date by reputable brokers.
    
 
    Bonds and other fixed income securities are valued according to the broadest
and most representative market, which will ordinarily be the over-the-counter
market. Net asset value includes interest on fixed income securities, which is
accrued daily. In addition, bonds and other fixed income securities may be
valued on the basis of prices provided by a pricing service when such prices are
believed to reflect the fair market value of such securities. The prices
provided by a pricing service are determined without regard to bid or last sale
prices, but take into account institutional size, trading in similar groups of
securities and any developments related to the specific securities. Securities
not priced in this manner are valued at the most recently quoted bid price or,
when securities exchange valuations are used, at the latest quoted sale price on
the day of valuation. If there is no such reported sale, the latest quoted bid
price will be used. Securities purchased with remaining maturities of 60 days or
less are valued at amortized cost, if it approximates market value. In the event
that amortized cost does not approximate market value, market prices as
determined above will be used.
 
   
    The value of other assets and securities for which quotations are not
readily available (including restricted securities and unlisted foreign
securities) and those securities the prices for which it is inappropriate to
determine the prices in accordance with the above-stated procedures are
determined in good faith at fair value using methods determined by the Board of
Directors. For purposes of calculating net asset value per share, all assets and
liabilities initially expressed in foreign currencies will be translated into
U.S. dollars at the mean of the bid and asked price of such currencies against
the U.S. dollar last quoted by any major bank.
    
 
    Although the legal rights of Class A and Class B shares will be identical,
the different expenses borne by each class will result in different net asset
values and dividends for the class. Dividends will differ by approximately the
amount of the distribution expense accrual differential among the classes. The
net asset value of Class B shares will generally be lower than the net asset
value of the Class A shares as a result of the distribution expense charged to
Class B shares.
 
                            PERFORMANCE INFORMATION
 
   
    The Fund may from time to time advertise "total return" for each class of
the Small Cap Value Equity, Value Equity and Balanced Portfolios. In addition,
from time to time the Fund may advertise "yield" for the Global Fixed Income and
High Yield Portfolios. THESE FIGURES ARE BASED ON HISTORICAL EARNINGS AND ARE
NOT INTENDED TO INDICATE FUTURE PERFORMANCE.
    
 
    Each Portfolio may advertise "total return" which shows what an investment
in a class of a Portfolio would have earned over a specified period of time
(such as one, five or ten years) assuming that all distributions and dividends
by the Portfolio were reinvested in the same class on the reinvestment dates
during the period. Total return does not take into account any federal or state
income taxes that may be payable on dividends and
 
                                       36
<PAGE>
distributions or on redemption. The "yield" of the Global Fixed Income and High
Yield Portfolios refers to the income generated by an investment in the
Portfolio over a month or 30-day period. This income is then annualized. That
is, the amount of income generated by the investment during that 30-day period
is assumed income generated each 30-day period for twelve periods, and is shown
as a percentage of the investment. The Fund may also include comparative
performance information in advertising or marketing the Portfolios' shares,
including data from Lipper Analytical Services, Inc., other industry
publications, business periodicals, rating service and market indices. For
further information concerning these figures, see "Calculation of Yield and
Total Return"in the Statement of Additional Information.
 
    The performance figures for Class B shares will generally be lower than
those for Class A shares because of the distribution fee charged to Class B
shares.
 
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
 
    All income dividends and capital gains distributions for a class of shares
will be automatically reinvested in additional shares at net asset value, except
that, upon written notice to the Fund or by checking off the appropriate box in
the Distribution Option Section on the Account Registration Form, a shareholder
may elect to receive income dividends and capital gains distributions in cash.
 
   
    Each Portfolio expects to distribute substantially all of its taxable net
investment income in the form of quarterly dividends. Net realized capital
gains, if any, after reduction for any available tax loss carryforwards will
also be distributed annually.
    
 
    Undistributed net investment income is included in a Portfolio's net assets
for the purpose of calculating net asset value per share. Therefore, on the
"ex-dividend" date, the net asset value per share excludes the dividend (i.e.,
is reduced by the per share amount of the dividend). Dividends paid shortly
after the purchase of shares by an investor, although in effect a return of
capital, are taxable to shareholders subject to tax.
 
    Because of the distribution fee and any other expenses that may be
attributable to the Class B shares, the net income attributable to and the
dividends payable on Class B shares will be lower than the net income
attributable to and the dividends payable on Class A shares. As a result, the
net asset value per share of the classes of the Portfolios will differ at times.
Expenses of the Portfolios allocated to a particular class of shares will be
borne on a pro rata basis by each outstanding share of that class.
 
                                     TAXES
 
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
 
    No attempt has been made to present a detailed explanation of the federal,
state, or local income tax treatment of a Portfolio or its shareholders.
Accordingly, shareholders are urged to consult their tax advisors regarding
specific questions as to federal, state and local income taxes.
 
    Each Portfolio is treated as a separate entity for federal income tax
purposes and is not combined with the Fund's other portfolios. Each Portfolio
intends to qualify for the special tax treatment afforded regulated investment
companies under Subchapter M of the Code so that the Portfolio will be relieved
of federal income tax on that part of its net investment income and net capital
gain that is distributed to shareholders.
 
                                       37
<PAGE>
   
    Each Portfolio intends to distribute substantially all of its taxable net
investment income (including, for this purpose, net short-term capital gain) to
shareholders. Dividends from a Portfolio's net investment income are taxable to
shareholders as ordinary income, whether received in cash or in additional
shares. Such dividends paid by a Portfolio, except the High Yield and Global
Equity Portfolios, will generally qualify for the 70% dividends-received
deduction for corporate shareholders to the extent of the aggregate qualifying
dividend income received by the Portfolio from U.S. corporations. Dividends paid
by the High Yield and Global Equity Portfolios will generally not qualify for
the 70% dividends-received deduction for corporate shareholders.
    
 
    Distributions of net capital gain (the excess of net long-term capital gain
over net short-term capital loss) are taxable to shareholders as long-term
capital gain, regardless of how long shareholders have held their shares. Each
Portfolio will send reports annually to shareholders of the federal income tax
status of all distributions made during the preceding year.
 
    Each Portfolio intends to make sufficient distributions or deemed
distributions of its ordinary income and capital gain net income (the excess of
short-term and long-term capital gains over short-term and long-term capital
loss, including any available capital loss carry-forwards), prior to the end of
each calendar year to avoid liability for federal excise tax.
 
    Dividends and other distributions declared by a Portfolio in October,
November or December of any year and payable to shareholders of record on a date
in such month will be deemed to have been paid by the Portfolio and received by
the shareholders in that year if the distributions are paid by the Portfolio at
any time during the following January.
 
   
    The Fund may be required to withhold and remit to the U.S. Treasury 31% of
any dividends, capital gains distributions and redemption proceeds paid to any
individual or certain other non-corporate shareholder (1) who has failed to
provide a correct taxpayer identification number (generally an individual's
social security number or non-individual's employer identification number) on
the Application Form, (2) who is subject to backup withholding by the Internal
Revenue Service, or (3) who has not certified to the Fund that such shareholder
is not subject to backup withholding. This backup withholding is not an
additional tax, and any amounts withheld may be credited against the
shareholder's ultimate U.S. tax liability.
    
 
    The sale, exchange or redemption of shares will result in taxable gain or
loss to the selling, exchanging or redeeming shareholder, depending upon whether
the fair market value of the sale, exchange or redemption proceeds exceed or are
less than the shareholder's adjusted basis in the sold, exchanged or redeemed
shares. If capital gain distributions have been made with respect to shares that
are sold at a loss after being held for six months or less, then the loss is
treated as a long-term capital loss to the extent of the capital gain
distributions.
 
    Conversion of shares between classes are not taxable events to the
shareholder.
 
    Shareholders are urged to consult with their tax advisors concerning the
application of state and local income taxes to investments in a Portfolio, which
may differ from the federal income tax consequences described above.
 
    THE TAX DISCUSSION SET FORTH ABOVE IS INCLUDED FOR GENERAL INFORMATION ONLY.
PROSPECTIVE INVESTORS SHOULD CONSULT THEIR OWN TAX ADVISERS WITH RESPECT TO THE
TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN A PORTFOLIO.
 
                                       38
<PAGE>
                             PORTFOLIO TRANSACTIONS
 
    The Adviser selects the brokers or dealers that will execute the purchases
and sales of investment securities for each of the Fund's portfolios. The
Adviser seeks the best execution of all portfolio transactions. A portfolio may
pay higher commission rates than the lowest available when the Adviser believes
it is reasonable to do so in light of the value of the research, statistical,
and pricing services provided by the broker effecting the transaction.
 
    It is not the Fund's practice to allocate brokerage or principal business on
the basis of sales of shares which may be made through intermediary brokers or
dealers. However, the Adviser may, consistent with NASD rules, place portfolio
orders with qualified broker-dealers who recommend the applicable portfolio to
their clients or who act as agents in the purchase of shares of the portfolio
for their clients.
 
    Subject to the overriding objective of obtaining the best execution of
orders, the Fund may use broker-dealer affiliates of the Adviser, including
Morgan Stanley, to effect portfolio brokerage transactions under procedures
adopted by the Fund's Board of Directors. For such transactions, the commission
rates and other remuneration paid to Morgan Stanley or other affiliates must be
fair and reasonable in comparison to those of other broker-dealers for
comparable transactions involving similar securities being purchased or sold
during a comparable time period.
 
PORTFOLIO TURNOVER
 
   
    The Portfolios generally do not invest for short-term trading purposes,
however, when circumstances warrant, each Portfolio may sell investment
securities without regard to the length of time they have been held. Market
conditions in a given year could result in a higher or lower portfolio turnover
rate than expected and the Portfolios will not consider portfolio turnover rate
a limiting factor in making investment decisions consistent with their
respective objectives and policies. For the fiscal year ended December 31, 1996,
the Global Fixed Income and High Yield Portfolios had portfolio turnover rates
of 258% and 117%, respectively. As portfolio turnover increases, the Portfolios
may expect to pay correspondingly increased brokerage and trading costs. In
addition to transaction costs, higher portfolio turnover may result in the
realization of capital gains. As discussed under "Taxes," to the extent net
short-term capital gains are realized, any distributions resulting from such
gains are considered ordinary income for federal income tax purposes.
    
 
                              GENERAL INFORMATION
 
DESCRIPTION OF COMMON STOCK
 
   
    The Fund was organized as a Maryland corporation on June 16, 1988. The
Articles of Incorporation, as amended and restated, permit the Fund to issue up
to 35 billion shares of common stock, with $.001 par value per share. Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number of shares the Fund is authorized to issue without the approval of the
shareholders of the Fund. The Board of Directors has the power to designate one
or more classes of shares of common stock and to classify and reclassify any
unissued shares with respect to such classes. The shares of common stock of each
portfolio are currently classified into two classes, the Class A shares and the
Class B shares, except for the International Small Cap, Money Market and
Municipal Money Market Portfolio which offer only Class A shares.
    
 
                                       39
<PAGE>
    The shares of each Portfolio, when issued, will be fully paid,
nonassessable, fully transferable and redeemable at the option of the holder.
The shares have no preference as to conversion, exchange, dividends, retirement
or other features and have no pre-emptive rights. The shares of each Portfolio
have non-cumulative rights, which means that the holders of more than 50% of the
shares voting for the election of Directors can elect 100% of the Directors if
they choose to do so. Persons or organizations owning 25% or more of the
outstanding shares of a Portfolio may be presumed to "control" (as that term is
defined in the 1940 Act) such Portfolio. Under Maryland law, the Fund is not
required to hold an annual meeting of its shareholders unless required to do so
under the 1940 Act.
 
REPORTS TO SHAREHOLDERS
 
    The Fund will send to its shareholders annual and semi-annual reports; the
financial statements appearing in annual reports are audited by independent
accountants. Monthly unaudited portfolio data are also available from the Fund
upon request.
 
    In addition, the Adviser or its agent, as Transfer Agent, will send to each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
 
CUSTODIAN
 
    Chase is the Fund's custodian for domestic and certain foreign assets. Chase
is not an affiliate of the Adviser or the Distributor. Morgan Stanley Trust
Company, Brooklyn, New York ("MSTC"), an affiliate of the Adviser and the
Distributor, acts as the Fund's custodian for assets held outside the United
States and employs subcustodians approved by the Board of Directors of the Fund
in accordance with regulations of the Securities and Exchange Commission for the
purpose of providing custodial services for such assets. MSTC may also hold
certain domestic assets for the Fund. For more information on the custodians,
see "General Information -- Custody Arrangements" in the Statement of Additional
Information.
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
    Chase Global Funds Services Company, 73 Tremont Street, Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
 
INDEPENDENT ACCOUNTANTS
 
   
    Price Waterhouse LLP serves as independent accountants for the Fund and
audits its annual financial statements.
    
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       40
<PAGE>
                                   APPENDIX A
                     DESCRIPTION OF CORPORATE BOND RATINGS
 
MOODY'S INVESTORS SERVICE CORPORATE BOND RATINGS:
 
    Aaa -- Bonds which are rated Aaa are judged to be the best quality. They
carry the smallest degree of investment risk and are generally referred to as
"gilt-edge." Interest payments are protected by a large or by an exceptionally
stable margin, and principal is secure. While the various protective elements
are likely to change, such changes as can be visualized are most unlikely to
impair the fundamentally strong position of such issues.
 
    Aa -- Bonds which are rated Aa are judged to be of high quality by all
standards. Together with the Aaa group they comprise what are generally known as
high grade bonds. They are rated lower than the best bonds because margins of
protection may not be as large as in Aaa securities or fluctuation of protective
elements may be of greater amplitude or there may be other elements present
which make the long-term risks appear somewhat larger than in Aaa securities.
 
    Moody's applies numerical modifiers 1, 2 and 3 in the Aa and A rating
categories. The modifier 1 indicates that the security ranks at a higher end of
the rating category, modifier 2 indicates a mid-range rating and the modifier 3
indicates that the issue ranks at the lower end of the rating category.
 
    A -- Bonds which are rated A possess many favorable investment attributes
and are to be considered as upper medium grade obligations. Factors giving
security to principal and interest are considered adequate but elements may be
present which suggest a susceptibility to impairment sometime in the future.
 
    Baa -- Bonds which are rated Baa are considered as medium grade obligations,
i.e., they are neither highly protected nor poorly secured. Interest payments
and principal security appear adequate for the present but certain protective
elements may be lacking or may be characteristically unreliable over any great
length of time. Such bonds lack outstanding investment characteristics and in
fact have speculative characteristics as well.
 
    Ba -- Bonds which are rated Ba are judged to have speculative elements;
their future cannot be considered as well assured. Often the protection of
interest and principal payments may be very moderate, and thereby not well
safeguarded during both good and bad times over the future. Uncertainty of
position characterizes bonds in this class.
 
    B -- Bonds which are rated B generally lack characteristics of the desirable
investment. Assurance of interest and principal payments or of maintenance of
other terms of the contract over any long period of time may be small.
 
    Caa -- Bonds which are rated Caa are of poor standing. Such issues may be in
default or there may be present elements of danger with respect to principal or
interest.
 
    Ca -- Bonds which are rated Ca represent obligations which are speculative
in a high degree. Such issues are often in default or have other marked
shortcomings.
 
    C -- Bonds which are rated C are the lowest rated class of bonds, and issues
so rated can be regarded as having extremely poor prospects of ever attaining
any real investment standing.
 
                                       41
<PAGE>
STANDARD & POOR'S RATINGS GROUP CORPORATE BOND RATINGS:
 
    AAA -- Bonds rated AAA have the highest rating assigned by Standard & Poor's
to a debt obligation and indicate an extremely strong capacity to pay principal
and interest.
 
    AA -- Bonds rated AA have a very strong capacity to pay interest and repay
principal and differ from the highest rated issues only to a small degree.
 
    A -- Bonds rated A have a strong capacity to pay interest and repay
principal although they are somewhat more susceptible to the adverse effects of
changes in circumstances and economic conditions than bonds in higher rated
categories.
 
    BBB -- Debt rated BBB is regarded as having an adequate capacity to pay
interest and repay principal. Whereas it normally exhibits adequate protection
parameters, adverse economic conditions or changing circumstances are more
likely to lead to a weakened capacity to pay interest and repay principal for
debt in this category than for debt in higher rated categories.
 
    BB, B, CCC, CC -- Debt rated BB, B, CCC and CC is regarded, on balance, as
predominantly speculative with respect to capacity to pay interest and repay
principal in accordance with the terms of the obligation. BB indicates the
lowest degree of speculation and CC the highest degree of speculation. While
such debt will likely have some quality and protective characteristics, these
are outweighed by large uncertainties or major risk exposures to adverse
conditions.
 
    C -- The rating C is reserved for income bonds on which no interest is being
paid.
 
    D -- Debt rated D is in default, and payment of interest and/or repayment of
principal is in arrears.
 
                                       42
<PAGE>
   MORGAN STANLEY INSTITUTIONAL FUND, INC.
   
          SMALL CAP VALUE EQUITY, VALUE EQUITY, BALANCED, GLOBAL FIXED INCOME
AND HIGH YIELD PORTFOLIOS
    
           P.O. BOX 2798, BOSTON, MA 02208-2798
 
                           ACCOUNT REGISTRATION FORM
 
<TABLE>
<C>   <S>                                            <C>
      ACCOUNT INFORMATION                            If you need assistance in filling out this form for the Morgan Stanley
      Fill in where applicable                       Institutional Fund, please contact your Morgan Stanley representative
                                                     or call us toll free 1-(800)-548-7786. Please print all items except
                                                     signature, and mail to the Fund at the address above.
  A)  REGISTRATION
      1. INDIVIDUAL
      2. JOINT TENANTS
         (RIGHTS OF SURVIVORSHIP PRESUMED UNLESS
         TENANCY IN COMMON
         IS INDICATED)
</TABLE>
 
1.
         First Name    Initial         Last Name
2.
         First Name    Initial         Last Name
         First Name    Initial         Last Name
 
<TABLE>
<C>   <S>                                            <C>
      3. CORPORATIONS,
         TRUSTS AND OTHERS
         Please call the Fund for additional
      documents that may be required to set up
      account and to authorize transactions.
</TABLE>
 
3.
 
<TABLE>
<S>                     <C>                 <C>                   <C>               <C>
Type of Registration:   / / INCORPORATED    / / UNINCORPORATED    / / PARTNERSHIP   / / UNIFORM GIFT/TRANSFER TO MINOR
                                            ASSOCIATION                               (ONLY ONE CUSTODIAN AND MINOR PERMITTED)
</TABLE>
 
/ / TRUST ________________________  / / OTHER (Specify) ________________________
<TABLE>
<C>        <S>                             <C>
       B)  MAILING ADDRESS
           Please fill in completely,
           including telephone number(s).
 
<CAPTION>
       B)
 
<CAPTION>
</TABLE>
 
/ / United States Citizen  / / Resident Alien
                   Street or P.O. Box
                   City
                   State                   Zip
Home Telephone No.                   Business Telephone No.
/ / Non-Resident Alien:
Permanent Address (Where you reside permanently for tax purposes)
                   Street Address
                   City
                   Country                   Postal Code
Home Telephone No.                    Business Telephone No.
 
Current Mailing Address (If different from Permanent Address)
                   Street Address
                   City
                   Country
Postal Code
Home Telephone No.                   Business Telephone No.
 
<TABLE>
<C>   <S>                                            <C>                                  <C>
  C)  TAXPAYER                                       Enter your Taxpayer Identification Number. For most individual
      IDENTIFICATION                                 taxpayers, this is your Social Security Number.
      NUMBER
      1. INDIVIDUAL
      2.   JOINT TENANTS
           (RIGHTS OF SURVIVORSHIP PRESUMED UNLESS
           TENANCY IN COMMON
           IS INDICATED)
      For Custodian account
      of a minor (Uniform
      Gifts/Transfers to Minor
      Acts), give the Social
      Security Number of
      the minor
                                                                                          OR
                                                     1.         TAXPAYER IDENTIFICATION                      SOCIAL SECURITY
                                                     NUMBER ("TIN")                                NUMBER ("SSN")
                                                                                              OR
                                                     2.                             TIN
                                                                                                                             SSN
                                                                                              OR
                                                     TIN
                                                                                                                             SSN
                                                     IMPORTANT TAX INFORMATION
                                                     You (as a payee) are required by law to provide us (as payer) with your
                                                     correct TIN(s) or SSN(s). Accounts that have a missing or incorrect
                                                     TIN(s) or SSN(s) will be subject to backup withholding at a 31% rate on
                                                     dividends, distributions and other payments. If you have not provided us
                                                     with your correct TIN(s) or SSN(s), you may be subject to a $50 penalty
                                                     imposed by the Internal Revenue Service.
                                                     Backup withholding is not an additional tax; the tax liability of
                                                     persons subject to backup withholding will be reduced by the amount of
                                                     tax withheld. If withholding results in an overpayment of taxes, a
                                                     refund may be obtained.
                                                     You may be notified that you are subject to backup withholding under
                                                     Section 3406(a)(1)(C) of the Internal Revenue Code because you have
                                                     underreported interest or dividends or you were required to, but failed
                                                     to, file a return which would have included a reportable interest or
                                                     dividend payment.
</TABLE>
 
<PAGE>
 
   
<TABLE>
<C>   <S>                                  <C>                             <C>                   <C>
  D)  PORTFOLIO AND                        For Purchase of the following   / / Class A Shares $  / / Class B Shares $
      CLASS SELECTION                      Portfolio(s):                   / / Class A Shares $  / / Class B Shares $
      (Class A shares minimum $500,000     Small Cap Value Equity          / / Class A Shares $  / / Class B Shares $
      for each Portfolio and Class B       Portfolio                       / / Class A Shares $  / / Class B Shares $
      shares minimum $100,000 for each     Value Equity Portfolio          / / Class A Shares $  / / Class B Shares $
      Portfolio. Please indicate           Balanced Portfolio
      Portfolio, class and amount.         Global Fixed Income Portfolio
                                           High Yield Portfolio
                                                                           Total Initial Investment $
</TABLE>
    
 
<TABLE>
<C>   <S>                        <C>
  E)  METHOD OF
      INVESTMENT
      Please indicate
      portfolio, manner of
      payment.
</TABLE>
 
Payment by:
 
/ / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND,
INC.--PORTFOLIO NAME)
 
<TABLE>
<S>                                                                          <C>
/ / Exchange $ From                                                                     -- - - - - - - - - - -- - -
                            Name of Portfolio                                                   Account No.
/ / Account previously established by:  / / Phone exchange  / / Wire on                 -- - - - - - - - - - -- - -
                                                                                      Account No.               (Check
                                                                                (Previously assigned by the Fund)     Digit)
                                                                                                                          Date
</TABLE>
 
<TABLE>
<C>   <S>                        <C>
  F)  DISTRIBUTION               Income dividends and capital gains distributions (if any) to
      OPTION                     be reinvested in additional shares unless either box below
                                 is checked.
                                 / / Income dividends to be paid in cash, capital gains
                                 distributions (if any) in shares.
                                 / / Income dividends and capital gains distributions (if
                                 any) to be paid in cash.
</TABLE>
 
<TABLE>
<C>   <S>                             <C>                                       <C>
  G)  TELEPHONE                       / / I/we hereby authorize the Fund and
      REDEMPTION                      its agents to honor any telephone         Name of COMMERCIAL Bank (Not Savings
      AND EXCHANGE                    requests to wire redemption proceeds to   Bank)
      OPTION                          the commercial bank indicated at right    Bank Account No.
      Please select at time of        and/or mail redemption proceeds to the
      initial application if you      name and address in which my/our fund
      wish to redeem or exchange      account is registered if such requests                                        Bank
      shares by telephone. A          are believed to be authentic.                                                  ABA
      SIGNATURE GUARANTEE IS          The Fund and the Fund's Transfer Agent                                         No.
      REQUIRED IF BANK ACCOUNT IS     will employ reasonable procedures to
      NOT REGISTERED IDENTICALLY TO   confirm that instructions communicated    Name(s) in which your BANK Account is
      YOUR FUND ACCOUNT.              by telephone are genuine. These           Established
      TELEPHONE REQUESTS FOR          procedures include requiring the
      REDEMPTIONS OR EXCHANGE WILL    investor to provide certain personal      Bank's Street
      NOT BE HONORED UNLESS THE BOX   identification information at the time    Address
      IS CHECKED.                     an account is opened and prior to
                                      effecting each transaction requested by   City  State  Zip
                                      telephone. In addition, all telephone
                                      transaction requests will be recorded
                                      and investors may be required to provide
                                      additional telecopied written
                                      instructions of transaction requests.
                                      Neither the Fund nor the Transfer Agent
                                      will be responsible for any loss,
                                      liability, cost or expense for following
                                      instructions received by telephone that
                                      it reasonably believes to be genuine.
</TABLE>
 
   
<TABLE>
<C>   <S>                                  <C>
  H)  INTERESTED PARTY
      OPTION                                                                                                Name
      In addition to the account
      statement sent to my/our registered
      address, I/we hereby authorize the                                                                   Address
      Fund to mail duplicate statements
      to the name and address provided at  City         State         Zip Code
      right.
</TABLE>
    
 
<TABLE>
<C>   <S>                                  <C>
  I)  DEALER
      INFORMATION
                                           Representative Name              Representative No.             Branch
                                           No.
</TABLE>
 
<TABLE>
<C>   <S>                                  <C>
  J)  SIGNATURE OF
      ALL HOLDERS
      AND TAXPAYER
      CERTIFICATION
      Sign Here ,
</TABLE>
 
<TABLE>
<S>                                  <C>
The undersigned certify that I/we have full authority and legal capacity
to purchase and redeem shares of the Fund and affirm that I/we have
received a current Prospectus of the Morgan Stanley Institutional Fund,
Inc. and agree to be bound by its terms.
  BY SIGNING THIS APPLICATION, I/WE HEREBY CERTIFY UNDER PENALTIES OF
PERJURY THAT THE INFORMATION ON THIS APPLICATION IS COMPLETE AND CORRECT
AND THAT AS REQUIRED BY FEDERAL LAW (PLEASE CHECK APPLICABLE BOXES
BELOW):
 
/ / U.S. CITIZEN(S)/TAXPAYER(S):
 
      / / I/WE CERTIFY THAT (1) THE NUMBER(S) SHOWN ABOVE ON THIS FORM
          IS/ARE THE CORRECT SSN(S) OR TIN(S) AND (2) I/WE ARE NOT
          SUBJECT TO ANY BACKUP WITHHOLDING EITHER BECAUSE (A) I/WE ARE
          EXEMPT FROM BACKUP WITHHOLDING; (B) I/WE HAVE NOT BEEN
          NOTIFIED BY THE INTERNAL REVENUE SERVICE ("IRS") THAT I/WE ARE
          SUBJECT TO BACKUP WITHHOLDING AS A RESULT OF A FAILURE TO
          REPORT ALL INTEREST OR DIVIDENDS; OR (C) THE IRS HAS NOTIFIED
          ME/US THAT I AM/WE ARE NO LONGER SUBJECT TO BACKUP
          WITHHOLDING.
 
      / / IF NO TIN(S) OR SSN(S) HAS/HAVE BEEN PROVIDED ABOVE, I/WE HAVE
          APPLIED, OR INTEND TO APPLY, TO THE IRS OR THE SOCIAL SECURITY
          ADMINISTRATION FOR A TIN OR A SSN AND I/WE UNDERSTAND THAT IF
          I/ WE DO NOT PROVIDE EITHER NUMBER TO CHASE GLOBAL FUNDS
          SERVICES COMPANY ("CGFSC") WITHIN 60 DAYS OF THE DATE OF THIS
          APPLICATION OR IF I/WE FAIL TO FURNISH MY/OUR CORRECT SSN(S)
          OR TIN(S), I/WE MAY BE SUBJECT TO A PENALTY AND A 31% BACKUP
          WITHHOLDING ON DISTRIBUTIONS AND REDEMPTION PROCEEDS. (PLEASE
          PROVIDE EITHER NUMBER ON IRS FORM W-9). YOU MAY REQUEST SUCH
          FORM BY CALLING CGFSC AT 800-282-4404.
 
/ / NON-U.S. CITIZEN(S)/TAXPAYER(S)
  UNDER PENALTIES OF PERJURY, I/WE CERTIFY THAT I/WE ARE NOT U.S.
CITIZENS OR RESIDENTS AND I/WE ARE EXEMPT FOREIGN PERSONS AS DEFINED BY
THE INTERNAL REVENUE SERVICE.
 
THE INTERNAL REVENUE SERVICE DOES NOT REQUIRE YOUR CONSENT TO ANY
PROVISION OF THIS DOCUMENT OTHER THAN THE CERTIFICATIONS REQUIRED TO
AVOID BACKUP WITHHOLDING.
 
                                     (X)
(X)                                  Signature (if joint account, both
Signature            Date            must sign)      Date
</TABLE>
<PAGE>
                 (This page has been left blank intentionally.)
<PAGE>
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
 
  NO DEALER, SALES REPRESENTATIVE OR ANY OTHER PERSON HAS BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS HAVING BEEN AUTHORIZED BY THE FUND OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION TO
ANY PERSON TO WHOM IT IS UNLAWFUL TO MAKE SUCH OFFER OR SOLICITATION IN SUCH
JURISDICTION.
 
                           --------------------------
 
                               TABLE OF CONTENTS
 
   
<TABLE>
<S>                                                 <C>
                                                    PAGE
                                                    ----
Fund Expenses.....................................    2
Financial Highlights..............................    4
Prospectus Summary................................   10
Investment Objectives and Policies................   14
Additional Investment Information.................   19
Investment Limitations............................   24
Management of the Fund............................   25
Purchase of Shares................................   28
Redemption of Shares..............................   33
Shareholder Services..............................   35
Valuation of Shares...............................   35
Performance Information...........................   36
Dividends and Capital Gains Distributions.........   37
Taxes.............................................   37
Portfolio Transactions............................   39
General Information...............................   39
Account Registration Form
</TABLE>
    
 
                        SMALL CAP VALUE EQUITY PORTFOLIO
                             VALUE EQUITY PORTFOLIO
                               BALANCED PORTFOLIO
                         GLOBAL FIXED INCOME PORTFOLIO
                              HIGH YIELD PORTFOLIO
 
                               PORTFOLIOS OF THE
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
 
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
 
- ---------------------------------
- ---------------------------------
- ---------------------------------
- ---------------------------------
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
     ----------------------------------------------------------------------
 
                      ACTIVE COUNTRY ALLOCATION PORTFOLIO
 
                               A PORTFOLIO OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
 
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
 
                                ----------------
 
   
    Morgan  Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company, or mutual fund, which offers redeemable shares in
a   series   of   diversified   and   non-diversified   investment    portfolios
("portfolios").  The  Fund  is  designed  to  provide  clients  with  attractive
alternatives for meeting their investment needs. The Fund currently consists  of
twenty-nine  portfolios representing a  broad range of  investment choices. This
prospectus (the "Prospectus") pertains to the Class A and the Class B shares  of
the Active Country Allocation Portfolio (the "Portfolio"). The Class A and Class
B  shares currently offered  by the Portfolio  have different minimum investment
requirements and fund  expenses. Shares of  the portfolios are  offered with  no
sales  charge, exchange  fee or redemption  fee, (except  that the International
Small Cap Portfolio may impose a transaction fee).
    
 
    The Fund is designed  to meet the investment  needs of discerning  investors
who  place a premium on quality and  personal service. With Morgan Stanley Asset
Management  Inc.  as   Adviser  and   Administrator  (the   "Adviser"  and   the
"Administrator"),  and with Morgan Stanley & Co. Incorporated ("Morgan Stanley")
as Distributor, the  Fund makes available  to institutional and  high net  worth
individual  investors a series  of portfolios which  benefit from the investment
expertise and commitment to  excellence associated with  Morgan Stanley and  its
affiliates.
 
    This Prospectus is designed to set forth concisely the information about the
Fund  that a prospective investor should know  before investing and it should be
retained for future reference. The  Fund offers additional portfolios which  are
described  in other prospectuses and under  "Prospectus Summary" below. The Fund
currently offers the following portfolios:  (i) GLOBAL AND INTERNATIONAL  EQUITY
- --  Active Country Allocation, Asian  Equity, Emerging Markets, European Equity,
Global Equity, Gold, International  Equity, International Magnum,  International
Small  Cap, Japanese Equity  and Latin American Portfolios;  (ii) U.S. EQUITY --
Aggressive Equity,  Emerging  Growth, Equity  Growth,  Small Cap  Value  Equity,
Technology, U.S. Real Estate and Value Equity Portfolios; (iii) EQUITY AND FIXED
INCOME  -- Balanced Portfolio; (iv) FIXED INCOME -- Emerging Markets Debt, Fixed
Income, Global Fixed Income, High Yield, and Municipal Bond Portfolios; and  (v)
MONEY  MARKET -- Money Market and  Municipal Money Market Portfolios. Additional
information  about  the  Fund  is  contained  in  a  "Statement  of   Additional
Information,"  dated May 1, 1997, which is incorporated herein by reference. The
Statement of Additional Information and the prospectuses pertaining to the other
portfolios of the Fund are available upon request and without charge by  writing
or calling the Fund at the address and telephone number set forth above.
 
THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES AND
    EXCHANGE  COMMISSION, NOR HAS THE  SECURITIES AND EXCHANGE COMMISSION
       PASSED UPON THE ACCURACY OR ADEQUACY OF THIS PROSPECTUS.   ANY
             REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.
 
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1997.
<PAGE>
                                 FUND EXPENSES
 
    The  following table illustrates the expenses and fees that a shareholder of
the Active Country Allocation Portfolio will incur:
 
<TABLE>
<CAPTION>
SHAREHOLDER TRANSACTION EXPENSES
- ------------------------------------------------------------------------------------------
<S>                                                                                         <C>
Maximum Sales Load Imposed on Purchases
  Class A.................................................................................        None
  Class B.................................................................................        None
Maximum Sales Load Imposed on Reinvested Dividends
  Class A.................................................................................        None
  Class B.................................................................................        None
Deferred Sales Load
  Class A.................................................................................        None
  Class B.................................................................................        None
Redemption Fees
  Class A.................................................................................        None
  Class B.................................................................................        None
Exchange Fees
  Class A.................................................................................        None
  Class B.................................................................................        None
</TABLE>
 
   
<TABLE>
<CAPTION>
ANNUAL FUND OPERATING EXPENSES
- ------------------------------------------------------------------------------------------
<S>                                                                                         <C>
 (AS A PERCENTAGE OF AVERAGE NET ASSETS)
Management Fee (Net of Fee Waiver)*
  Class A.................................................................................       0.36%
  Class B.................................................................................       0.36%
12b-1 Fees
  Class A.................................................................................        None
  Class B.................................................................................       0.25%
Other Expenses
  Class A.................................................................................       0.44%
  Class B.................................................................................       0.44%
                                                                                            -----------
Total Operating Expenses (Net of Fee Waivers)*
  Class A.................................................................................       0.80%
  Class B.................................................................................       1.05%
                                                                                            -----------
                                                                                            -----------
</TABLE>
    
 
- ------------------------
   
*The Adviser has  agreed to waive  its management fees  and/or to reimburse  the
 Portfolio,  if necessary, if  such fees would cause  the total annual operating
 expenses of the Portfolio  to exceed a specified  percentage of its  respective
 average  daily net assets. Absent  the fee waiver, the  management fee would be
 0.65%. Absent  the fee  waiver and/or  expense reimbursement,  the  Portfolio's
 total  operating expenses would be 1.09% of the average daily net assets of the
 Class A shares and 1.33% of the average daily net assets of the Class B shares.
 As a result of this  reduction, the Management Fee  stated above is lower  than
 the contractual fee stated under "Management of the Fund." The Adviser reserves
 the  right to terminate any of its fee waivers and/or expense reimbursements at
 any time in its sole discretion. For further information on Fund expenses,  see
 "Management of the Fund."
    
 
                                       2
<PAGE>
    The  purpose of the table  above is to assist  the investor in understanding
the various expenses  that an investor  in the Portfolio  will bear directly  or
indirectly.  Expenses and fees are  based on actual figures  for the fiscal year
ended December 31, 1996. Due to the  continuous nature of Rule 12b-1 fees,  long
term  Class  B shareholders  may pay  more  than the  equivalent of  the maximum
front-end sales  charges  otherwise permitted  by  the National  Association  of
Securities Dealers, Inc. ("NASD") Conduct Rules.
 
    The  following  example illustrates  the expenses  that you  would pay  on a
$1,000 investment assuming (1) a 5% annual rate of return and (2) redemption  at
the  end of each time period.  As noted in the table  above, the Fund charges no
redemption fees  of  any kind.  The  following example  is  based on  the  total
operating expenses of the Portfolio after fee waivers.
 
   
<TABLE>
<CAPTION>
                                                                       1 YEAR       3 YEARS      5 YEARS     10 YEARS
                                                                     -----------  -----------  -----------  -----------
<S>                                                                  <C>          <C>          <C>          <C>
Active Country Allocation Portfolio
  Class A..........................................................   $       8    $      26    $      44    $      99
  Class B..........................................................          11           33           58          128
</TABLE>
    
 
    THIS  EXAMPLE SHOULD  NOT BE CONSIDERED  A REPRESENTATION OF  PAST OR FUTURE
EXPENSES OR  PERFORMANCE. ACTUAL  EXPENSES MAY  BE GREATER  OR LESS  THAN  THOSE
SHOWN.
 
                                       3
<PAGE>
                              FINANCIAL HIGHLIGHTS
 
   
    The  following table provides financial highlights for the Class A and Class
B shares  of  the Portfolio  for  each of  the  periods presented.  The  audited
financial  highlights  for  the  Portfolio's  shares  for  each  of  the periods
presented are part of the Fund's financial statements which appear in the Fund's
December 31, 1996 Annual  Report to Shareholders and  which are incorporated  by
reference  in the  Fund's Statement  of Additional  Information. The Portfolio's
financial highlights for  each of  the periods  presented have  been audited  by
Price  Waterhouse LLP, whose unqualified report  thereon is also incorporated by
reference in  the Statement  of Additional  Information. Additional  performance
information  is  included  in  the  Annual Report.  The  Annual  Report  and the
financial  statements   therein,  along   with  the   Statement  of   Additional
Information, are available at no cost from the Fund at the address and telephone
number  noted on the cover page of  this Prospectus. After October 31, 1992 (the
Fund's prior fiscal year end), the Fund changed its fiscal year end to  December
31.  The following information should be  read in conjunction with the financial
statements and notes thereto.
    
 
                                       4
<PAGE>
   
                      ACTIVE COUNTRY ALLOCATION PORTFOLIO
    
   
<TABLE>
<CAPTION>
                                                                                CLASS A
                                     ---------------------------------------------------------------------------------------------
                                                                                                                      PERIOD FROM
                                                                                                      TWO MONTHS      JANUARY 17,
                                      YEAR ENDED      YEAR ENDED      YEAR ENDED      YEAR ENDED         ENDED         1992* TO
                                     DECEMBER 31,    DECEMBER 31,    DECEMBER 31,    DECEMBER 31,    DECEMBER 31,     OCTOBER 31,
                                         1996            1995            1994            1993            1992            1992
                                     -------------   -------------   -------------   -------------   -------------   -------------
<S>                                  <C>             <C>             <C>             <C>             <C>             <C>
NET ASSET VALUE, BEGINNING OF
 PERIOD............................  $   11.63       $   11.65       $   12.21       $    9.59       $    9.37       $   10.00
                                     -------------   -------------   -------------   -------------   -------------   -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)........       0.24            0.17            0.19            0.13            0.02            0.11
  Net Realized and Unrealized Gain
   (Loss) on Investments...........       0.88            1.00           (0.25)           2.75            0.20           (0.74)
                                     -------------   -------------   -------------   -------------   -------------   -------------
    Total from Investment
     Operations....................       1.12            1.17           (0.06)           2.88            0.22           (0.63)
                                     -------------   -------------   -------------   -------------   -------------   -------------
DISTRIBUTIONS
  Net Investment Income............      (0.81)          (0.25)          (0.14)          (0.09)             --              --
  In Excess of Net Investment
   Income..........................      (0.02)          (0.10)             --           (0.08)             --              --
  Net Realized Gain................      (0.48)          (0.84)          (0.36)             --              --              --
  In Excess of Net Realized Gain...         --              --              --           (0.09)             --              --
                                     -------------   -------------   -------------   -------------   -------------   -------------
    Total Distributions............      (1.31)          (1.19)          (0.50)          (0.26)             --              --
                                     -------------   -------------   -------------   -------------   -------------   -------------
NET ASSET VALUE, END OF PERIOD.....  $   11.44       $   11.63       $   11.65       $   12.21       $    9.59       $    9.37
                                     -------------   -------------   -------------   -------------   -------------   -------------
                                     -------------   -------------   -------------   -------------   -------------   -------------
TOTAL RETURN.......................       9.71%          10.57%          (0.52)%         30.72%           2.35%          (6.30)%
                                     -------------   -------------   -------------   -------------   -------------   -------------
                                     -------------   -------------   -------------   -------------   -------------   -------------
RATIOS AND SUPPLEMENTAL DATA:
  Net Assets, End of Period
   (Thousands).....................   $183,193        $170,663        $182,977        $150,854         $50,234         $47,534
  Ratio of Expenses to Average Net
   Assets (1)......................       0.80%           0.80%           0.80%           0.80%           0.80%**         0.88%**
  Ratio of Net Investment Income to
   Average Net Assets (1)..........       1.22%           1.26%           1.43%           1.29%           1.22%**         2.32%**
  Portfolio Turnover Rate..........         65%             72%             51%             53%              2%             62%
  Average Commission Rate #........    $0.0028             N/A             N/A             N/A             N/A             N/A
- ------------------------------
(1) Effect of voluntary expense
    limitation during the period:
     Per share benefit to net
      investment income............      $0.03           $0.05           $0.03           $0.05           $0.01           $0.03
   Ratios before expense
    limitation:
     Expenses to Average Net
      Assets.......................       1.09%           1.18%           1.00%           1.33%           1.70%**         1.58%**
     Net Investment Income to
      Average Net Assets...........       0.94%           0.88%           1.23%           0.76%           0.32%**         1.62%**
 
<CAPTION>
                                        CLASS B
                                     -------------
 
                                      PERIOD FROM
                                      JANUARY 2,
                                      1996*** TO
                                     DECEMBER 31,
                                         1996
                                     -------------
<S>                                  <C>
NET ASSET VALUE, BEGINNING OF
 PERIOD............................  $   11.66
                                     -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)........       0.06
  Net Realized and Unrealized Gain
   (Loss) on Investments...........       1.00
                                     -------------
    Total from Investment
     Operations....................       1.06
                                     -------------
DISTRIBUTIONS
  Net Investment Income............      (0.78)
  In Excess of Net Investment
   Income..........................      (0.02)
  Net Realized Gain................      (0.48)
  In Excess of Net Realized Gain...         --
                                     -------------
    Total Distributions............      (1.28)
                                     -------------
NET ASSET VALUE, END OF PERIOD.....  $   11.44
                                     -------------
                                     -------------
TOTAL RETURN.......................       9.22%
                                     -------------
                                     -------------
RATIOS AND SUPPLEMENTAL DATA:
  Net Assets, End of Period
   (Thousands).....................       $633
  Ratio of Expenses to Average Net
   Assets (1)......................       1.05%**
  Ratio of Net Investment Income to
   Average Net Assets (1)..........       1.09%**
  Portfolio Turnover Rate..........         65%
  Average Commission Rate #........    $0.0028
- ------------------------------
(1) Effect of voluntary expense
    limitation during the period:
     Per share benefit to net
      investment income............      $0.02
   Ratios before expense
    limitation:
     Expenses to Average Net
      Assets.......................       1.33%**
     Net Investment Income to
      Average Net Assets...........       0.82%**
</TABLE>
    
 
   
  * Commencement of Operations.
    
   
 ** Annualized
    
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
   
 # Beginning with fiscal year  1996, the Portfolio is  required to disclose  the
   average  commission rate  per share  it paid  for portfolio  trades, on which
   commissions were charged, during the period. For the year ended December  31,
   1996,  the average commission  rate paid on trades  on which commissions were
   charged was 0.11% of the trade amount.
    
 
                                       5
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
 
    The  Fund  consists  of   twenty-nine  portfolios,  offering   institutional
investors  and high net  worth individual investors a  broad range of investment
choices coupled with the advantages of a no-load mutual fund with Morgan Stanley
and its affiliates providing customized  services as Adviser, Administrator  and
Distributor.  Each portfolio offers Class A shares and, except the International
Small Cap, Money Market and Municipal Money Market Portfolios, also offers Class
B shares. Each portfolio has its own investment objective and policies  designed
to  meet its specific goals. The investment objective of the Portfolio described
in this Prospectus is as follows:
 
    -The  ACTIVE   COUNTRY   ALLOCATION  PORTFOLIO   seeks   long-term   capital
     appreciation  by investing in accordance with country weightings determined
     by the  Adviser in  equity securities  of non-U.S.  issuers which,  in  the
     aggregate, replicate broad country indices.
 
    The  other portfolios of the Fund  are described in other prospectuses which
may be obtained from the Fund at the address and phone number noted on the cover
page of this Prospectus. The investment objectives of these other portfolios are
listed below:
 
    GLOBAL AND INTERNATIONAL EQUITY:
 
    -The  ASIAN  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation   by
     investing primarily in equity securities of Asian issuers.
 
    -The  CHINA GROWTH PORTFOLIO seeks to provide long-term capital appreciation
     by investing  primarily in  equity securities  of issuers  in The  People's
     Republic of China, Hong Kong and Taiwan.
 
    -The  EMERGING  MARKETS PORTFOLIO  seeks  long-term capital  appreciation by
     investing primarily in equity securities of emerging country issuers.
 
    -The EUROPEAN  EQUITY  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing primarily in equity securities of European issuers.
 
    -The  GLOBAL  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing primarily in equity securities  of issuers throughout the  world,
     including U.S. issuers.
 
    -The  GOLD  PORTFOLIO  seeks  long-term  capital  appreciation  by investing
     primarily in equity securities of  foreign and domestic issuers engaged  in
     gold-related activities.
 
    -The  INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation by
     investing primarily in equity securities of non-U.S. issuers.
 
    -The INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation  by
     investing  primarily in equity securities  of non-U.S. issuers domiciled in
     EAFE countries.
 
    -The INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital  appreciation
     by  investing primarily in  the equity securities  of non-U.S. issuers with
     equity market capitalizations of less than $1 billion.
 
    -The JAPANESE  EQUITY  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing primarily in equity securities of Japanese issuers.
 
                                       6
<PAGE>
   
    -The  LATIN  AMERICAN  PORTFOLIO  seeks  long-term  capital  appreciation by
     investing primarily in  equity securities  of Latin  American issuers  and,
     from  time to time, debt securities  issued or guaranteed by Latin American
     governments or governmental entities.
    
    US EQUITY:
 
    -The AGGRESSIVE  EQUITY PORTFOLIO  seeks capital  appreciation by  investing
     primarily in corporate equity and equity-linked securities.
 
    -The  EMERGING  GROWTH  PORTFOLIO seeks  long-term  capital  appreciation by
     investing primarily  in  growth-oriented  equity securities  of  small-  to
     medium-sized corporations.
 
    -The  EQUITY  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing  in  growth-oriented  equity  securities  of  medium  and   large
     capitalization companies.
 
    -The  MICROCAP PORTFOLIO  seeks long-term capital  appreciation by investing
     primarily in growth-oriented equity securities of small corporations.
 
    -The SMALL CAP VALUE EQUITY PORTFOLIO  seeks high long-term total return  by
     investing  in  undervalued  equity  securities  of  small-  to medium-sized
     companies.
 
    -The TECHNOLOGY PORTFOLIO seeks long-term capital appreciation by  investing
     primarily  in equity  securities of companies  that, in the  opinion of the
     Portfolio's  investment  adviser,  are  expected  to  benefit  from   their
     involvement in technology and technology-related industries.
 
    -The  U.S.  REAL ESTATE  PORTFOLIO seeks  to  provide above  average current
     income and long-term capital appreciation by investing primarily in  equity
     securities  of companies in  the U.S. real  estate industry, including real
     estate investment trusts.
 
    -The VALUE EQUITY PORTFOLIO seeks high  total return by investing in  equity
     securities  which the  Adviser believes to  be undervalued  relative to the
     stock market in general at the time of purchase.
    EQUITY AND FIXED INCOME:
 
    -The BALANCED PORTFOLIO seeks high total return while preserving capital  by
     investing  in  a combination  of  undervalued equity  securities  and fixed
     income securities.
    FIXED INCOME:
 
    -The EMERGING MARKETS DEBT  PORTFOLIO seeks high  total return by  investing
     primarily   in  debt  securities   of  government,  government-related  and
     corporate issuers located in emerging countries.
 
    -The FIXED INCOME PORTFOLIO seeks to produce a high total return  consistent
     with the preservation of capital by investing in a diversified portfolio of
     fixed income securities.
 
    -The  GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real rate
     of return while preserving capital by investing in fixed income  securities
     of issuers throughout the world, including U.S. issuers.
 
    -The  HIGH YIELD PORTFOLIO seeks to maximize  total return by investing in a
     diversified portfolio of high  yield fixed income  securities that offer  a
     yield  above  that  generally available  on  debt securities  in  the three
     highest rating categories of the recognized rating services.
 
    -The MORTGAGE-BACKED SECURITIES PORTFOLIO seeks  to produce as high a  level
     of  current income  as is  consistent with  the preservation  of capital by
     investing  primarily  in  a  variety  of  investment-grade  mortgage-backed
     securities.
 
                                       7
<PAGE>
    -The  MUNICIPAL  BOND PORTFOLIO  seeks to  produce a  high level  of current
     income consistent with preservation of principal by investing primarily  in
     municipal  obligations, the interest on which is exempt from federal income
     tax.
    MONEY MARKET:
 
    -The MONEY MARKET PORTFOLIO  seeks to maximize  current income and  preserve
     capital  while maintaining  high levels  of liquidity  through investing in
     high quality money market instruments with remaining maturities of one year
     or less.
 
    -The MUNICIPAL MONEY MARKET PORTFOLIO  seeks to maximize current  tax-exempt
     income  and  preserve capital  while maintaining  high levels  of liquidity
     through investing in high quality  money market instruments with  remaining
     maturities of one year or less which are exempt from federal income tax.
 
    THE  CHINA GROWTH,  MICROCAP AND  MORTGAGE-BACKED SECURITIES  PORTFOLIOS ARE
CURRENTLY NOT BEING OFFERED.
 
INVESTMENT MANAGEMENT
 
   
    Morgan Stanley Asset Management  Inc., a wholly  owned subsidiary of  Morgan
Stanley  Group  Inc.,  which,  together  with  its  affiliated  asset management
companies, at March  31, 1997  had in  excess of  $118 billion  in assets  under
management  as  an  investment  manager  or  as  a  fiduciary  adviser,  acts as
investment adviser to the  Fund and each of  its portfolios. See "Management  of
the Fund -- Investment Adviser" and "Management of the Fund -- Administrator."
    
 
HOW TO INVEST
 
    Class  A shares of  the Portfolio are  offered directly to  investors at net
asset value with no  sales commission or  12b-1 charges. Class  B shares of  the
Portfolio  are offered at net  asset value with no  sales commission, but with a
12b-1 fee, which  is accrued daily  and paid  quarterly, equal to  0.25% of  the
Class B shares' average daily net assets on an annualized basis. Share purchases
may  be  made  by  sending  investments directly  to  the  Fund  or  through the
Distributor. The minimum initial investment, generally, is $500,000 for Class  A
shares  of the Portfolio and  $100,000 for Class B  shares of the Portfolio. The
minimum  initial  investment  amount  is  reduced  for  certain  categories   of
investors.  For additional  information on  how to  purchase shares  and minimum
initial investments, see "Purchase of Shares".
 
HOW TO REDEEM
 
    Shares of the Portfolio may  be redeemed at any  time, without cost, at  the
net  asset value  per share  of shares of  the applicable  class next determined
after receipt of  the redemption request.  The redemption price  may be more  or
less  than the purchase  price. Certain redemptions  that cause the  value of an
account to remain for  a continuous 60-day period  below the minimum  investment
amount  for  Class A  shares or  for Class  B shares  may result  in involuntary
redemption or automatic conversion. For additional information on how to  redeem
shares  and involuntary  redemption or  conversion, see  "Purchase of  Shares --
Minimum Account Sizes and Involuntary  Redemption of Shares" and "Redemption  of
Shares."
 
RISK FACTORS
 
    The   investment  policies  of  the   Portfolio  entail  certain  risks  and
considerations of which an investor should  be aware. The Portfolio will  invest
in securities of foreign issuers, including issuers in emerging countries, which
 
                                       8
<PAGE>
   
are  subject to certain risks not typically associated with domestic securities,
including (1) restrictions on foreign investment and on repatriation of  capital
invested  in  foreign  countries, (2)  currency  fluctuations, (3)  the  cost of
converting foreign currency  into U.S. dollars,  (4) potential price  volatility
and  lesser liquidity of shares traded  on foreign country securities markets or
lack of a  secondary trading market  for such securities  and (5) political  and
economic risks, including the risk of nationalization or expropriation of assets
and  the risk  of war.  In addition,  accounting, auditing,  financial and other
reporting standards in foreign  countries are not  equivalent to U.S.  standards
and  therefore, disclosure of  certain material information may  not be made and
less information may be  available to investors  investing in foreign  countries
than  in the United States. There is also generally less governmental regulation
of the  securities  industry  in  foreign  countries  than  the  United  States.
Moreover,  it may be more difficult to obtain  a judgment in a court outside the
United States.  The  Portfolio  may invest  in  certain  derivatives,  including
options,  futures and options on futures. These investments entail certain costs
and risks, including imperfect correlation between the value of securities  held
by  the Portfolio and the value of the particular derivative instrument, and the
risk that the Portfolio could not close out a derivatives position when it would
be most  advantageous  to  do so.  In  addition,  the Portfolio  may  invest  in
repurchase  agreements, lend its portfolio  securities, purchase securities on a
when-issued basis  and invest  in foreign  currency forward  contracts to  hedge
currency   risk  associated  with  investment  in  non-U.S.  dollar  denominated
securities. Each of  these investment strategies  involves specific risks  which
are   described  under  "Investment  Objective  and  Policies"  and  "Additional
Investment Information."
    
 
                                       9
<PAGE>
                       INVESTMENT OBJECTIVE AND POLICIES
 
    The investment objective of  the Portfolio is  to provide long-term  capital
appreciation  by investing in  accordance with country  weightings determined by
the Adviser in equity  securities of non-U.S. issuers  which, in the  aggregate,
replicate  broad country  indices. The Adviser  utilizes a  top-down approach in
selecting investments for  the Portfolio that  emphasizes country selection  and
weighting  rather than  individual stock  selection. This  approach reflects the
Adviser's philosophy  that a  diversified selection  of securities  representing
exposure to world markets, based upon the economic outlook and current valuation
levels for each country, is an effective way to maximize the return and minimize
the  risk associated  with international investment.  The Portfolio's investment
objective is a fundamental policy which may not be changed without the  approval
of  a majority  of the  Portfolio's outstanding  voting securities.  There is no
assurance that the Portfolio will attain its objective.
 
   
    The Portfolio invests primarily in  equity securities, which include  common
and  preferred stock, convertible securities and rights and warrants to purchase
common stocks. In addition  to the investments  and strategies described  below,
the  Portfolio may invest in certain securities  and obligations as set forth in
"Additional Investment  Information" below.  The investment  policies  described
below  are  not  fundamental policies  and  may be  changed  without shareholder
approval.
    
 
   
    The Adviser determines country allocations  for the Portfolio on an  ongoing
basis  within policy ranges dictated by each country's market capitalization and
liquidity. The Portfolio will invest in the industrialized countries  throughout
the  world that comprise the Morgan  Stanley Capital International EAFE (Europe,
Australia and the Far  East) Index. The Portfolio  will also invest in  emerging
country  equity securities.  With respect to  the Portfolio,  the term "emerging
country" applies  to  any country  which,  in the  opinion  of the  Adviser,  is
generally  considered to be  an emerging country  by the international financial
community, including the International  Bank for Reconstruction and  Development
(more   commonly  known  as  the  World  Bank)  and  the  International  Finance
Corporation. There are currently over 130 countries which, in the opinion of the
Adviser, are generally considered to be emerging countries by the  international
financial  community, approximately  40 of  which currently  have stock markets.
These countries generally include  every nation in the  world except the  United
States,  Canada,  Japan,  Australia, New  Zealand  and most  nations  located in
Western Europe. Currently, investing in many emerging countries is not  feasible
or  may involve unacceptable risks. The  Portfolio will focus its investments on
those  emerging  market  countries  in  which  it  believes  the  economies  are
developing  strongly and in  which the markets  are becoming more sophisticated.
With respect  to the  portion of  the  Portfolio that  is invested  in  emerging
country  equity securities, the Portfolio  currently intends to invest primarily
in some or all of the following countries:
    
 
<TABLE>
<S>              <C>
Argentina        Portugal
Brazil           Philippines
India            South Africa
Indonesia        South Korea
Malaysia         Thailand
Mexico           Turkey
</TABLE>
 
As markets  in other  countries develop,  the Portfolio  expects to  expand  and
further diversify the emerging countries in which it invests. The Portfolio does
not  intend to  invest in any  security in a  country where the  currency is not
freely convertible  to  U.S. dollars,  unless  the Portfolio  has  obtained  the
necessary governmental
 
                                       10
<PAGE>
licensing to convert such currency or other appropriately licensed or sanctioned
contractual guarantee to protect such investment against loss of that currency's
external  value, or the Portfolio  has a reasonable expectation  at the time the
investment is  made  that such  governmental  licensing or  other  appropriately
licensed or sanctioned guarantee would be obtained or that the currency in which
the  security is quoted would be freely  convertible at the time of any proposed
sale of the security by the Portfolio.
 
    By analyzing a variety of  macroeconomic and political factors, the  Adviser
develops  fundamental  projections  on  interest  rates,  currencies,  corporate
profits and economic growth for each country. These country projections are used
then to determine what  the Adviser believes  to be a fair  value for the  stock
market  of each  country. Discrepancies between  actual value and  fair value as
determined by the Adviser provide an expected return for each stock market.  The
expected  return is  adjusted by currency  return expectations  derived from the
Adviser's purchasing-power parity exchange rate  model to arrive at an  expected
total  return in  U.S. dollars.  The final  country allocation  decision is then
arrived at by considering the expected total return in light of various  country
specific  considerations such as market  size, volatility, liquidity and country
risk.
 
   
    Within a particular country,  investments are made  through the purchase  of
equity  securities which, in aggregate, replicate a broad market index, which in
most cases will be the Morgan Stanley Capital International index for the  given
country.  The Adviser  may overweight  or underweight  an industry  segment of a
particular index if it concludes this would be advantageous to the Portfolio. An
issuer may be considered to be from  a particular country if, in the opinion  of
the  Adviser,  it has  one or  more  of the  following characteristics:  (i) its
principal securities  trading market  is in  that country,  (ii) alone  or on  a
consolidated  basis it  derives 50%  or more of  its annual  revenue from either
goods produced, sales made or services performed in that country; or (iii) it is
organized under the laws of,  and has a principal  office in, that country.  The
Adviser  will  base  determinations  as  to  eligibility  on  publicly available
information and inquiries made to  the companies. Indexation of the  Portfolio's
stock   selection  reduces  stock-specific   risk  through  diversification  and
minimizes transaction costs, which can be substantial in foreign markets.
    
 
    Common stocks purchased for the Portfolio normally will be listed on a major
stock exchange in  the subject  country. The Portfolio  will not  invest in  the
stocks  of U.S. issuers. For a description of special considerations and certain
risks associated with investments in foreign issuers, see "Additional Investment
Information." The  Portfolio  may  temporarily reduce  its  equity  holdings  in
response  to adverse  market conditions and  invest in  domestic, Eurodollar and
foreign short-term money market instruments for defensive purposes.
 
                                       11
<PAGE>
                       ADDITIONAL INVESTMENT INFORMATION
 
   
    FOREIGN CURRENCY FORWARD CONTRACTS.   The Portfolio  may enter into  foreign
currency  forward contracts ("forward contracts")  that provide for the purchase
or sale of an amount of a specified currency at a future date. The Portfolio may
use such contracts to  protect against a decline  in a foreign currency  against
the  U.S. dollar between the  trade date and settlement  date when the Portfolio
purchases or sells securities,  lock in the U.S.  dollar value of dividends  and
interest  on securities held by the Portfolio, and generally to protect the U.S.
dollar  value  of  securities  held  by  the  Portfolio  against  exchange  rate
fluctuation.  While forward contracts  may limit losses as  a result of exchange
rate fluctuations, they will also limit any gains that might otherwise have been
realized. The Portfolio's  Custodian may  be required  to place  cash or  liquid
securities  in  a segregated  account in  an amount  equal to  the value  of the
Portfolio's total assets committed to the consummation of forward contracts.  If
the  value  of  the  securities  placed  in  the  segregated  account  declines,
additional cash or securities will be placed in the account on a daily basis  so
that  the value  of the  account will  be at  least equal  to the  amount of the
Portfolio's commitments with respect to such contracts.
    
 
    FOREIGN INVESTMENT.  Investment in  obligations of foreign issuers  involves
somewhat  different investment  risks than  those affecting  obligations of U.S.
issuers. There may  be limited  publicly available information  with respect  to
foreign  issuers,  and  foreign issuers  are  not generally  subject  to uniform
accounting, auditing  and financial  standards  and requirements  comparable  to
those  applicable  to  domestic companies.  There  may also  be  less government
supervision and regulation of foreign  securities exchanges, brokers and  listed
companies  than  in  the United  States.  Many foreign  securities  markets have
substantially  less  volume  than   U.S.  national  securities  exchanges,   and
securities  of  some foreign  issuers  are less  liquid  and more  volatile than
securities  of  comparable  U.S.   issuers.  Brokerage  commissions  and   other
transaction  costs on foreign securities exchanges  are generally higher than in
the United States. Dividends and interest paid by foreign issuers may be subject
to withholding and  other foreign taxes,  which may decrease  the net return  on
foreign investments as compared to dividends and interest paid to the Portfolios
by  domestic companies. Additional  risks include future  political and economic
developments, the possibility that a foreign jurisdiction might impose or change
withholding taxes on income payable with respect to foreign securities, possible
seizure, nationalization  or  expropriation of  the  foreign issuer  or  foreign
deposits, and the possible adoption of foreign governmental restrictions such as
exchange  controls.  Many  emerging  countries may  have  less  stable political
environments than more developed  countries. Also, it may  be more difficult  to
obtain a judgment in a court outside the United States.
 
    Such investments in securities of foreign issuers are frequently denominated
in  foreign currencies, and since the  Portfolio may temporarily hold uninvested
reserves in bank deposits  in foreign currencies, the  value of the  Portfolio's
assets  as measured in U.S. dollars may  be affected favorably or unfavorably by
changes in currency rates and in exchange control regulations, and the Portfolio
may incur costs in connection with conversions between various currencies.
 
   
    FUTURES CONTRACTS  AND OPTIONS  ON  FUTURES CONTRACTS.   The  Portfolio  may
purchase  and sell futures contracts and options on futures contracts, including
but not limited to financial futures, securities index futures, foreign currency
exchange futures, and interest rate futures contracts. Futures contracts provide
for the sale by one party and purchase by another party of a specified amount of
a specified security, instrument or basket
    
 
                                       12
<PAGE>
   
thereof, at a  specific future date  and at a  specified price. An  option on  a
futures  contract is a legal contract that gives  the holder the right to buy or
sell a specified amount  of futures contracts at  a fixed or determinable  price
upon the exercise of the option.
    
 
   
    The  Portfolio may  sell securities  index futures  contracts and/or options
thereon in anticipation of or during a  market decline to attempt to offset  the
decrease in market value of investments in its portfolio, or purchase securities
index  futures in order to gain market exposure. Subject to applicable laws, the
Portfolio may engage in transactions in securities index futures contracts  (and
options  thereon)  which  are  traded  on  a  recognized  securities  or futures
exchange, or  may purchase  or  sell such  instruments in  the  over-the-counter
market. There currently are limited securities index futures and options on such
futures  in many countries,  particularly emerging countries.  The nature of the
strategies adopted by the Adviser, and the extent to which those strategies  are
used, may depend on the development of such markets.
    
 
   
    The Portfolio may engage in transactions involving foreign currency exchange
futures  contracts. Such contracts  involve an obligation to  purchase or sell a
specific currency  at a  specified future  date and  at a  specified price.  The
Portfolio may engage in such transactions to hedge their respective holdings and
commitments  against changes in  the level of  future currency rates  or to gain
exposure to a particular currency.
    
 
   
    The  Portfolio  may  engage  in   transactions  in  interest  rate   futures
transactions.  Interest rate futures contracts involve an obligation to purchase
or sell a specific  debt security, instrument or  basket thereof at a  specified
future  date at  a specified price.  The value  of the contract  rises and falls
inversely with  changes in  interest rates.  The Portfolio  may engage  in  such
transactions  to hedge their holdings of debt instruments against future changes
in interest rates.
    
 
   
    Financial futures are futures  contracts relating to financial  instruments,
such  as  U.S. Government  securities, foreign  currencies, and  certificates of
deposit. Such contracts  involve an obligation  to purchase or  sell a  specific
security, instrument or basket thereof at a specified future date at a specified
price.  Like interest  rate futures  contracts, the  value of  financial futures
contracts rises  and  falls  inversely  with  changes  in  interest  rates.  The
Portfolio  may engage in financial futures contracts for hedging and non-hedging
purposes.
    
 
   
    Under rules  adopted  by  the  Commodity  Futures  Trading  Commission,  the
Portfolio  may enter into futures contracts and options thereon for both hedging
and non-hedging purposes,  provided that  not more  than 5%  of the  Portfolio's
total  assets at the time of entering the transaction are required as margin and
option  premiums  to  secure  obligations  under  such  contracts  relating   to
activities  that do not  constitute "bona fide" hedging.  The Portfolio will not
enter into futures contracts to the  extent that its outstanding obligations  to
purchase  securities under such  contracts, in combination  with its outstanding
obligations with respect to options transactions (including options to  purchase
securities or instruments) would exceed 20% of its total assets.
    
 
   
    Gains  and losses  on futures  contracts and  options thereon  depend on the
Adviser's ability  to  predict correctly  the  direction of  securities  prices,
interest  rates and other economic factors.  Other risks associated with the use
of futures  and options  are (i)  imperfect correlation  between the  change  in
market  value of investments held by the Portfolio and the prices of futures and
options relating to  investments purchased or  sold by the  Portfolio, and  (ii)
possible  lack  of a  liquid secondary  market  for a  futures contract  and the
resulting inability to  close a futures  position. The risk  that the  Portfolio
will  be unable  to close  out a  futures position  or options  contract will be
minimized by only entering  into futures contracts  or options transactions  for
which there
    
 
                                       13
<PAGE>
   
appears to be a liquid exchange or secondary market. The risk of loss in trading
on  futures contracts in some strategies can be substantial, due both to the low
margin deposits required and the extremely  high degree of leverage involved  in
futures pricing.
    
 
    LOANS  OF PORTFOLIO  SECURITIES.  The  Portfolio may lend  its securities to
brokers, dealers, domestic and foreign banks or other financial institutions for
the purpose of increasing its net investment income. These loans must be secured
continuously by cash or equivalent collateral or by a letter of credit at  least
equal  to the  market value  of the securities  loaned plus  accrued interest or
income. There may be risks of delay  in recovery of the securities or even  loss
of  rights  in  the  collateral  should  the  borrower  of  the  securities fail
financially. The  Portfolio will  not enter  into securities  loan  transactions
exceeding  in the aggregate 33 1/3% of the market value of the Portfolio's total
assets.
 
   
    MONEY MARKET INSTRUMENTS.   The Portfolio  is permitted to  invest in  money
market   instruments,  although  the  Portfolio  intends  to  stay  invested  in
securities satisfying its primary investment objective to the extent  practical.
The  Portfolio may  make money  market investments  pending other  investment or
settlement for  liquidity, or  in adverse  market conditions.  The money  market
investments  permitted  for  the  Portfolio  include  obligations  of  the  U.S.
Government and  its  agencies  and  instrumentalities;  obligations  of  foreign
sovereignties;  other  debt  securities;  commercial  paper;  bank  obligations;
certificates of  deposit (including  Eurodollar  certificates of  deposit);  and
repurchase agreements.
    
 
   
    OPTIONS  TRANSACTIONS.  The Portfolio may seek to increase its return or may
hedge its portfolio  investments through  options transactions  with respect  to
securities,  instruments, indices or baskets thereof  in which the Portfolio may
invest, as well  as with respect  to foreign currency.  Purchasing a put  option
gives  the Portfolio the right to sell  a specified security, currency or basket
of securities or currencies  at the exercise price  until the expiration of  the
option.  Purchasing a call  option gives the  Portfolio the right  to purchase a
specified security,  currency  or basket  of  securities or  currencies  at  the
exercise  price  until  the expiration  of  the  option. The  Portfolio  may not
purchase call and  put options to  the extent  that the value  of its  aggregate
investment in options exceeds 5% of its total assets.
    
 
   
    The  Portfolio  also  may  write  (i.e.,  sell)  put  and  call  options  on
investments held in its portfolio, as well as with respect to foreign  currency.
A  Portfolio that has written an option  receives a premium, which increases the
Portfolio's return on  the underlying security  or instrument in  the event  the
option  expires unexercised or is closed out  at a profit. However, by writing a
call option, the Portfolio will limit its opportunity to profit from an increase
in the market value of the underlying security or instrument above the  exercise
price  of the option for as long as  the Portfolio's obligation as writer of the
option continues. The  Portfolio may only  write options that  are "covered."  A
covered  call option  means that so  long as  the Portfolio is  obligated as the
writer of the  option, it  will own (i)  the underlying  security or  instrument
subject  to  the  option  or  (ii)  securities  or  instruments  convertible  or
exchangeable without  the payment  of  any consideration  into the  security  or
instrument subject to the option.
    
 
   
    By  writing (or selling) a put option, the Portfolio incurs an obligation to
buy the security or instrument underlying  the option from the purchaser of  the
put  at the option's exercise price at any time during the option period, at the
purchaser's election. Options written by the Portfolio may be exercisable by the
purchaser only on a  specific date. A  Portfolio that has  written a put  option
will  earmark or  segregate sufficient  liquid assets  to cover  its obligations
under the option.
    
 
                                       14
<PAGE>
   
    The Portfolio may  engage in  transactions in  options which  are traded  on
recognized  exchanges or  over-the-counter. There currently  are limited options
markets in  many  countries,  particularly  emerging  countries  such  as  Latin
American  countries, and the nature of the strategies adopted by the Adviser and
the extent to which those strategies are used will depend on the development  of
such  option markets. The primary  risks associated with the  use of options are
(i) imperfect  correlation between  the change  in market  value of  investments
held,  purchased or sold by the Portfolio  and the prices of options relating to
such investments; and  (ii) possible lack  of a liquid  secondary market for  an
option.
    
 
    REPURCHASE  AGREEMENTS.  The Portfolio  may enter into repurchase agreements
with brokers, dealers or  banks that meet the  credit guidelines adopted by  the
Fund's  Board  of Directors.  In a  repurchase agreement,  the Portfolio  buys a
security from a seller  that has agreed  to repurchase it  at a mutually  agreed
upon  date and price, reflecting the interest rate effective for the term of the
agreement. The term of  these agreements is usually  from overnight to one  week
and  never exceeds  one year.  Repurchase agreements  may be  viewed as  a fully
collateralized loan  of money  by the  Portfolio to  the seller.  The  Portfolio
always  receives securities with a  market value at least  equal to the purchase
price (including accrued interest)  as collateral and  this value is  maintained
during  the term  of the  agreement. If the  seller defaults  and the collateral
value declines, the Portfolio might incur a loss. If bankruptcy proceedings  are
commenced  with  respect to  the seller,  the  Portfolio's realization  upon the
collateral may  be  delayed  or  limited.  The  Portfolio  may  not  enter  into
repurchase  agreements with more  than seven days  to maturity if,  as a result,
more than  10% of  the  market value  of the  Portfolio's  net assets  would  be
invested  in such repurchase  agreements and other  investments for which market
quotations are not readily available or which are otherwise illiquid.
 
    WHEN-ISSUED AND DELAYED  DELIVERY SECURITIES.   The  Portfolio may  purchase
securities  on a  when-issued or delayed  delivery basis.  In such transactions,
instruments are bought with payment and  delivery taking place in the future  in
order  to secure what is considered to be  an advantageous yield or price at the
time of the transaction. Delivery of  and payment for these securities may  take
as  long as a month or  more after the date of  the purchase commitment but will
take place  no more  than 120  days after  the trade  date. The  Portfolio  will
maintain  with the Custodian  a separate account with  a segregated portfolio of
cash or liquid securities in an amount at least equal to these commitments.  The
payment  obligation and the interest rates that  will be received are each fixed
at the time the Portfolio enters into the commitment and no interest accrues  to
the  Portfolio until settlement. Thus,  it is possible that  the market value at
the time of settlement could be higher  or lower than the purchase price if  the
general  level of  interest rates  has changed.  It is  a current  policy of the
Portfolio not to enter into when-issued commitments exceeding, in the aggregate,
15% of the market value of  the Portfolio's total assets less liabilities  other
than the obligations created by these commitments.
 
                             INVESTMENT LIMITATIONS
 
    As  a  diversified  investment  company, the  Portfolio  is  subject  to the
following limitations: (a) as to 75% of its total assets, the Portfolio may  not
invest  more than 5%  of its total assets  in the securities  of any one issuer,
except   obligations   of   the   U.S.   Government   and   its   agencies   and
instrumentalities,  and  (b) the  Portfolio may  not  own more  than 10%  of the
outstanding voting securities of any one issuer.
 
    The Portfolio also operates under  certain investment restrictions that  are
deemed  fundamental limitations and may be changed only with the approval of the
holders  of   a   majority   of   the   Portfolio's   outstanding   shares   and
 
                                       15
<PAGE>
under certain non-fundamental investment limitations that may be changed without
shareholder   approval.   For   additional   information   on   fundamental  and
non-fundamental  investment   limitations,  see   "Investment  Limitations"   in
Statement of Additional Information.
 
                             MANAGEMENT OF THE FUND
 
   
    INVESTMENT ADVISER.  Morgan Stanley Asset Management Inc. is the Adviser and
Administrator  of the  Fund and the  Portfolio. The  Adviser provides investment
advice and portfolio  management services,  pursuant to  an Investment  Advisory
Agreement  and, subject  to the  supervision of  the Fund's  Board of Directors,
makes each of the Portfolio's day-to-day investment decisions, arranges for  the
execution  of  portfolio  transactions  and  generally  manages  the Portfolio's
investments. The  Adviser  is  entitled  to  receive  from  the  Active  Country
Allocation Portfolio an annual management fee, payable quarterly, equal to 0.65%
of the average daily net assets of the Portfolio.
    
 
    The  fees  of  the  Portfolio  are  higher  than  those  of  most investment
companies' because the Portfolio  invests internationally. The Adviser  believes
that  the fees are comparable to those of other investment companies that invest
internationally. The Adviser has agreed to a reduction in the fees payable to it
and to reimburse  the Portfolio, if  necessary, if such  fees would cause  total
annual  operating expenses of the Portfolio to exceed 0.80% of the average daily
net assets of the Class A shares of the Portfolio and 1.05% of the average daily
net assets of the Class B shares of the Portfolio.
 
   
    The Adviser, with  principal offices  at 1221  Avenue of  the Americas,  New
York,  New York  10020, conducts a  worldwide portfolio  management business and
provides a broad  range of  portfolio management  services to  customers in  the
United  States and abroad.  On February 5,  1997, Morgan Stanley  Group Inc. and
Dean Witter, Discover &  Co. announced that they  had entered into an  Agreement
and  Plan of Merger to  form Morgan Stanley, Dean  Witter, Discover & Co. Morgan
Stanley Group  Inc. is  the direct  parent of  the Adviser  and Morgan  Stanley.
Subject  to certain conditions  being met, it is  currently anticipated that the
transaction will close in mid-1997.  Thereafter, the Adviser and Morgan  Stanley
will be subsidiaries of Morgan Stanley, Dean Witter, Discover & Co. At March 31,
1997,  the  Adviser, together  with its  affiliated asset  management companies,
managed investments totaling in excess of $118 billion, including  approximately
$100  billion  under active  management and  $18 billion  as Named  Fiduciary or
Fiduciary Adviser. See "Management of the  Fund" in the Statement of  Additional
Information.
    
 
    PORTFOLIO  MANAGERS.  BARTON  M. BIGGS, MADHAV DHAR,  FRANCINE J. BOVICH AND
ANN D.  THIVIERGE. Barton  M. Biggs  has been  Chairman and  a director  of  the
Adviser  since 1980 and a Managing Director  of Morgan Stanley since 1975. He is
also a director  of Morgan Stanley  Group Inc.  and a director  and chairman  of
various  registered investment companies to which the Adviser and certain of its
affiliates provide investment  advisory services.  Mr. Biggs holds  a B.A.  from
Yale  University  and an  M.B.A.  from New  York  University. Madhav  Dhar  is a
Managing Director of Morgan Stanley. He joined  the Adviser in 1984 to focus  on
global  asset allocation  and investment  strategy and now  is a  co-head of the
Adviser's emerging markets  group. He  is the  portfolio manager  of the  Fund's
Emerging  Markets Portfolio, the  Emerging Markets and  Global Equity Allocation
Funds of the Morgan Stanley Fund, Inc., and the Morgan Stanley Emerging  Markets
Fund,  Inc.  (a  closed-end investment  company  listed  on the  New  York Stock
Exchange). He holds a B.S. (honors) from St. Stephens College, Delhi  University
(India),  and an M.B.A. from  Carnegie-Mellon University. Francine Bovich joined
the Adviser as a Principal in 1993. She is responsible for product  development,
portfolio  management  and  communication  of  the  Adviser's  asset  allocation
strategy to  institutional  investor  clients.  Previously,  Ms.  Bovich  was  a
Principal and
 
                                       16
<PAGE>
Executive Vice President of Westwood Management Corp. ("Westwood"), a registered
investment  adviser. Before  joining Westwood,  she was  a Managing  Director of
Citicorp Investment Management, Inc. (now Chancellor Capital Management),  where
she  was  responsible for  the  Institutional Investment  Management  Group. Ms.
Bovich began her investment career with Banker's Trust Company. She holds a B.A.
in Economics from  Connecticut College and  an M.B.A. in  Finance from New  York
University.  Ann Thivierge is a Principal of the Adviser. She is a member of the
Adviser's asset  allocation committee,  primarily  representing the  Total  Fund
Management  team since its  inception in 1991.  Prior to joining  the Adviser in
1986, she  spent two  years at  Edgewood Management  Company, a  privately  held
investment  management  firm.  Ms.  Thivierge  holds  a  B.A.  in  International
Relations from James Madison College,  Michigan State University, and an  M.B.A.
in Finance from New York University.
 
    ADMINISTRATOR.   The  Adviser also  provides administrative  services to the
Fund pursuant to an  Administration Agreement. The  services provided under  the
Administration  Agreement are subject to the supervision of the Officers and the
Board of Directors of the Fund and include day-to-day administration of  matters
related  to the  corporate existence  of the  Fund, maintenance  of its records,
preparation  of  reports,  supervision  of  the  Fund's  arrangements  with  its
custodian   and  assistance  in  the  preparation  of  the  Fund's  registration
statements under federal laws. The  Administration Agreement also provides  that
the  Administrator,  through its  agents, will  provide dividend  disbursing and
transfer agent services to the Fund.  For its services under the  Administration
Agreement,  the Fund  pays the Adviser  a monthly  fee which on  an annual basis
equals 0.15% of the average daily net assets of the Portfolio.
 
   
    Under an  agreement  between  the  Adviser  and  The  Chase  Manhattan  Bank
("Chase"),  Chase provides certain  administrative services to  the Fund through
its corporate  affiliate, Chase  Global Funds  Services Company  ("CGFSC").  The
Adviser  supervises and monitors such administrative services provided by CGFSC.
Their services are also subject to the supervision of the Board of Directors  of
the  Fund. CGFSC's business address is  73 Tremont Street, Boston, Massachusetts
02108-3913.
    
 
   
    LOCAL ADMINISTRATOR FOR THE  PORTFOLIO.  The Portfolio  has, as required  by
local  law, entered into an administration  agreement with a local administrator
in Brazil. A  local administrator  provides certain services  for the  Portfolio
with  respect to the Portfolio's investments in that country, including services
relating to  foreign exchange,  local taxes,  remittance of  income and  capital
gains,  and repatriation of  investments. The Portfolio's  local adminstrator in
Brazil, Unibanco-Uniao, a Brazilian corporation, is  paid by the Fund an  annual
fee of 0.125% of the Portfolio's average weekly net assets invested in Brazil.
    
 
    DIRECTORS  AND OFFICERS.  Pursuant to  the Fund's Articles of Incorporation,
the Board of  Directors decides upon  matters of general  policy and review  the
actions  of  the Fund's  Adviser, Administrator,  Distributor and  other service
providers. The Officers  of the Fund  conduct and supervise  its daily  business
operations.
 
    DISTRIBUTOR.   Morgan  Stanley serves  as the  exclusive Distributor  of the
shares of  the Fund.  Under its  Distribution Agreement  with the  Fund,  Morgan
Stanley  sells shares  of the Fund  upon the  terms and at  the current offering
price described in this Prospectus. Morgan Stanley is not obligated to sell  any
certain number of shares of the Portfolio.
 
    The  Portfolio currently offers  only the classes of  shares offered by this
Prospectus. The Portfolio may in the future offer one or more classes of  shares
with  features, distribution expenses or other  expenses that are different from
those of the classes currently offered.
 
                                       17
<PAGE>
    The  Fund has  adopted a Plan  of Distribution  with respect to  the Class B
shares pursuant  to Rule  12b-1 under  the Investment  Company Act  of 1940,  as
amended  (the  "1940 Act")  (the  "Plan"). Under  the  Plan, the  Distributor is
entitled to receive  from the  Portfolio a  distribution fee,  which is  accrued
daily  and paid  quarterly, of 0.25%  of the  Class B shares'  average daily net
assets on an annualized basis. The Distributor expects to reallocate most of its
fee to its investment representatives.  The Distributor may, in its  discretion,
voluntarily  waive from time to time all  or any portion of its distribution fee
and each of the Distributor and the Adviser is free to make additional  payments
out  of its own  assets to promote  the sale of  Fund shares, including payments
that compensate financial institutions for distribution services or  shareholder
services.
 
    The  Plan is designed to compensate the Distributor for its services, not to
reimburse the Distributor for its expenses,  and the Distributor may retain  any
portion  of the fee that it does not expend in fulfillment of its obligations to
the Fund.
 
    EXPENSES.  The Portfolio  is responsible for payment  of certain other  fees
and  expenses  (including  legal  fees, accountants'  fees,  custodial  fees and
printing and mailing  costs) specified  in the  Administration and  Distribution
Agreements.
 
                               PURCHASE OF SHARES
 
    Class  A and  Class B shares  of the Portfolio  may be purchased  at the net
asset value per share next determined after receipt of the purchase order by the
Portfolio. See "Valuation of Shares."
 
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
 
    For a  Portfolio  account  opened  on  or after  January  2,  1996  (a  "New
Account"),  the minimum initial investment and minimum account size are $500,000
for Class A shares and  $100,000 for Class B  shares. Certain advisory or  asset
allocation  accounts, such as Total Funds Management accounts, managed by Morgan
Stanley or  its  affiliates,  including the  Adviser  ("Managed  Accounts")  may
purchase Class A shares without being subject to such minimum initial investment
or  minimum account size requirements for  a Portfolio account. Employees of the
Adviser and certain  of its affiliates  may purchase Class  A Shares subject  to
conditions, including a lower minimum investment, established by Officers of the
Fund.
 
    If  the  value of  a  New Account,  containing  Class A  shares  falls below
$500,000  (but   remains  at   or  above   $100,000)  because   of   shareholder
redemption(s),  the Fund will  notify the shareholder, and  if the account value
remains below  $500,000 (but  remains at  or above  $100,000) for  a  continuous
60-day period, the Class A shares in such account will convert to Class B shares
and will be subject to the distribution fee and other features applicable to the
Class  B shares. The Fund,  however, will not convert Class  A shares to Class B
shares based solely upon changes in the  market that reduce the net asset  value
of  shares. Under current tax  law, conversions between share  classes are not a
taxable event to the shareholder.
 
    Shares in a Portfolio account opened  prior to January 2, 1996 (a  "Pre-1996
Account")  were  designated Class  A  shares on  January  2, 1996.  Shares  in a
Pre-1996 Account  with  a  value  of  $100,000 or  more  on  March  1,  1996  (a
"Grandfathered  Class A Account") remained Class  A shares regardless of account
size thereafter. Except for  shares in a Managed  Account, shares in a  Pre-1996
Account  with a value of  less than $100,000 on  March 1, 1996 (a "Grandfathered
Class B Account") converted  to Class B shares  on March 1, 1996.  Grandfathered
Class A Accounts and Managed Accounts are not subject to conversion from Class A
shares to Class B shares.
 
                                       18
<PAGE>
    Investors  may also invest in the Fund  by purchasing shares through a trust
department, broker, dealer, agent, financial planner, financial services firm or
investment adviser.  An  investor  may  be  charged  an  additional  service  or
transaction fee by that institution.
 
    The minimum investment levels may be waived at the discretion of the Adviser
for  (i) certain employees and customers of Morgan Stanley or its affiliates and
certain  trust  departments,  brokers,  dealers,  agents,  financial   planners,
financial  services  firms, or  investment advisers  that  have entered  into an
agreement with  Morgan  Stanley  or  its affiliates;  and  (ii)  retirement  and
deferred  compensation plans and trusts used  to fund such plans, including, but
not limited to, those defined in Section  401(a), 403(b) or 457 of the  Internal
Revenue  Code of  1986, as  amended (the  "Code") and  "rabbi trusts."  The Fund
reserves the right to modify or terminate the conversion features of the  shares
as stated above at any time upon 60-days notice to shareholders.
 
    The  Adviser reserves the right in its sole discretion to determine which of
such advisory  or  asset allocation  accounts  shall be  Managed  Accounts.  For
information  regarding  Managed  Accounts, please  contact  your  Morgan Stanley
account representative or the Fund at the telephone number provided on the cover
of this Prospectus.
 
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
 
    If the value of  a New Account falls  below $100,000 because of  shareholder
redemption(s),  the Fund will  notify the shareholder, and  if the account value
remains below  $100,000 for  a  continuous 60-day  period,  the shares  in  such
account  are subject to redemption  by the Fund and,  if redeemed, the net asset
value of  such  shares will  be  promptly paid  to  the shareholder.  The  Fund,
however,  will not redeem  shares based solely  upon changes in  the market that
reduce the net asset value of shares.
 
    Grandfathered Class A Accounts, Grandfathered  Class B Accounts and  Managed
Accounts  are not subject to involuntary redemption. The Fund reserves the right
to modify or  terminate the  involuntary redemption  features of  the shares  as
stated above at any time upon 60-days notice to shareholders.
 
CONVERSION FROM CLASS B TO CLASS A SHARES
 
    If the value of Class B shares in a Portfolio account increases, whether due
to  shareholder share  purchases or  market activity,  to $500,000  or more, the
Class B shares  will convert  to Class  A Shares.  Under current  tax law,  such
conversion  is not a taxable event to  the shareholder. Class A shares converted
from Class B shares  are subject to the  same minimum account size  requirements
that  are applicable to New Accounts containing Class A shares, as stated above.
The Fund reserves the  right to modify or  terminate this conversion feature  at
any time upon 60-days notice to shareholders.
 
INITIAL PURCHASES DIRECTLY FROM THE FUND
 
    The  Fund's determination of an investor's eligibility to purchase shares of
a given class  will take precedence  over the investor's  selection of a  class.
Assuming  the investor is eligible for the  class, the Fund will select the most
favorable class for the investor, if the investor has not done so.
 
                                       19
<PAGE>
INITIAL INVESTMENTS
 
1) BY CHECK.   An account may  be opened  by completing and  signing an  Account
   Registration Form and mailing it, together with a check ($500,000 minimum for
   Class  A  shares of  the Portfolio  and $100,000  for Class  B shares  of the
   Portfolio, with certain  exceptions for Morgan  Stanley employees and  select
   customers)  payable to "Morgan Stanley Institutional Fund, Inc. -- [portfolio
   name]", to:
 
      Morgan Stanley Institutional Fund, Inc.
      P.O. Box 2798
      Boston, Massachusetts 02208-2798
 
   
    Payment will  be accepted only  in U.S. dollars,  unless prior approval  for
  payment  by other currencies is given by  the Fund. The class(es) of shares of
  the Portfolio to be purchased should be designated on the Account Registration
  Form. For purchases  by check, the  Fund is ordinarily  credited with  Federal
  Funds  within  one business  day. Thus  your  purchase of  shares by  check is
  ordinarily credited to your account  at the net asset  value per share of  the
  Portfolio determined on the next business day after receipt.
    
 
2) BY  FEDERAL  FUNDS WIRE.   Purchases  may be  made by  having your  bank wire
   Federal Funds to the Fund's bank  account. In order to ensure prompt  receipt
   of your Federal Funds Wire, it is important that you follow these steps:
 
A.   Telephone  the Fund  (toll free: 1-800-548-7786)  and provide  us with your
    name, address,  telephone  number,  Social Security  or  Tax  Identification
    Number,  the  portfolio(s) selected,  the class  selected, the  amount being
    wired, and by  which bank.  We will  then provide  you with  a Fund  account
    number.  (Investors with existing accounts should also notify the Fund prior
    to wiring funds.)
 
B.   Instruct  your  bank to  wire  the  specified amount  to  the  Fund's  Wire
    Concentration  Bank Account (be sure  to have your bank  include the name of
    the portfolio(s)  selected,  the  class  selected  and  the  account  number
    assigned to you) as follows:
 
   
    The Chase Manhattan Bank
    One Manhattan Plaza
    New York, NY 10081-1000
    ABA #021000021
    DDA #910-2-733293
    Attn: Morgan Stanley Institutional Fund, Inc.
    Ref: (Portfolio name, your account number, your account name)
    
 
    Please call the Fund at 1-800-548-7786 prior to wiring funds.
 
C.   Complete and sign the Account Registration  Form and mail it to the address
    shown thereon.
 
  The purchase price of the Class A and  Class B shares of the Portfolio is  the
  net asset value next determined after the order is received. See "Valuation of
  Shares."  An order received prior to the  close of the New York Stock Exchange
  ("NYSE"), which is currently 4:00 p.m.  Eastern Time, will be executed at  the
  price
 
                                       20
<PAGE>
  computed on the date of receipt; an order received after the close of the NYSE
  will  be executed at  the price computed on  the next day the  NYSE is open as
  long as the Transfer Agent receives payment by check or in Federal Funds prior
  to the regular close of the NYSE on such day.
 
  Federal Funds purchase orders will be accepted only on a day on which the Fund
  and Chase (the "Custodian Bank") are open for business. Your bank may charge a
  service fee for wiring Federal Funds.
 
3) BY BANK WIRE.   The  same procedure outlined  under "By  Federal Funds  Wire"
   above  must be  followed in  purchasing shares  by bank  wire. However, money
   transferred by bank wire may or may  not be converted into Federal Funds  the
   same  day, depending on the time the  money is received and the bank handling
   the wire. Prior to such conversion, an investor's money will not be  invested
   and, therefore, will not be earning dividends. Your bank may charge a service
   fee for wiring funds.
 
ADDITIONAL INVESTMENTS
 
    You  may  add to  your account  at any  time (minimum  additional investment
$1,000, except  for  automatic  reinvestment  of  dividends  and  capital  gains
distributions for which there are no minimums) by purchasing shares at net asset
value  by mailing a check to the  Fund (payable to "Morgan Stanley Institutional
Fund, Inc. -- [portfolio name]") at the above address or by wiring monies to the
Custodian Bank as outlined above. It  is very important that your account  name,
the  portfolio name and the class selected be specified in the letter or wire to
assure proper  crediting to  your account.  In order  to ensure  that your  wire
orders  are invested  promptly, you  are requested to  notify one  of the Fund's
representatives (toll-free 1-800-548-7786)  prior to the  wire date.  Additional
investments will be applied to purchase additional shares in the same class held
by a shareholder in a Portfolio account.
 
OTHER PURCHASE INFORMATION
 
    Although  the legal rights of Class A  and Class B shares will be identical,
the different expenses borne  by each class will  result in different net  asset
values  and dividends. The net  asset value of Class  B shares will generally be
lower than the net asset value of Class A shares as a result of the distribution
expense charged to Class B shares. It  is expected, however, that the net  asset
value  per share of the two classes  will tend to converge immediately after the
recording of dividends  which will  differ by  approximately the  amount of  the
distribution expense accrual differential between the classes.
 
    In  the interest  of economy and  convenience, and because  of the operating
procedures of the Fund, certificates  representing shares of the Portfolio  will
not  be issued. All shares  purchased are confirmed to  you and credited to your
account on the Fund's books  maintained by the Adviser  or its agents. You  will
have  the  same  rights  and  ownership  with  respect  to  such  shares  as  if
certificates had been issued.
 
    To ensure that checks are collected by the Fund, withdrawals of  investments
made  by check are  not presently permitted  until payment for  the purchase has
been received,  which may  take up  to eight  business days  after the  date  of
purchase.  As a condition  of this offering,  if a purchase  is cancelled due to
nonpayment or because your check does not clear, you will be responsible for any
loss the Fund or its  agents incur. If you are  already a shareholder, the  Fund
may  redeem shares from your account(s) to  reimburse the Fund or its agents for
any loss. In addition,  you may be prohibited  or restricted from making  future
investments in the Fund.
 
    Investors  may  also invest  in the  Fund by  purchasing shares  through the
Distributor.
 
                                       21
<PAGE>
EXCESSIVE TRADING
 
   
    Frequent  trades  involving  either   substantial  portfolio  assets  or   a
substantial  portion of your  account or accounts controlled  by you can disrupt
management of a portfolio and raise its expenses. Consequently, in the  interest
of  all the stockholders  of the Portfolio and  the Portfolio's performance, the
Fund may in its discretion bar  a stockholder that engages in excessive  trading
of  shares of any class  of a portfolio from further  purchases of shares of the
Fund for an indefinite period. The  Fund considers excessive trading to be  more
than  one purchase and sale involving shares of the same class of a portfolio of
the Fund  within  any  120-day  period. As  an  example,  exchanging  shares  of
portfolios  of  the Fund  as follows  amounts  to excessive  trading: exchanging
shares of  Portfolio A  for shares  of Portfolio  B, then  exchanging shares  of
Portfolio B for shares of Portfolio C and again exchanging shares of Portfolio C
for shares of Portfolio B within a 120-day period. Two types of transactions are
exempt from these excessive trading restrictions: (1) trades exclusively between
money  market  portfolios;  and (2)  trades  done  in connection  with  an asset
allocation service, such as TFM Accounts  or accounts managed or advised by  the
Adviser and/or any of its affiliates.
    
 
INVESTMENT IN FUNDS THROUGH A TOTAL FUNDS MANAGEMENT ("TFM") ACCOUNT
 
   
    In  addition to the considerable diversification among individual securities
you receive by investing in a particular Portfolio, you can further reduce  risk
by  spreading  your assets  among several  different  Portfolios that  each have
different  risk  and  return  characteristics.  TFM  is  an  active   investment
management service managed by Morgan Stanley or its affiliates, including Morgan
Stanley  Asset  Management Inc.  (each, a  "TFM  Adviser"), that  allocates your
investments across a combination of either Class A or Class B shares of  certain
of  the Portfolios selected to meet your long-term investment objectives as well
as, in certain circumstances, your current income objectives.
    
 
   
    The TFM Adviser has developed investment strategies for TFM Accounts to meet
the diverse financial needs of different  investors. You can open a TFM  Account
by  meeting with one  of the investment professionals  of a Participating Dealer
who will review your situation and  help you identify your long-term  investment
and/or  current income  objectives. After using  TFM criteria  to determine your
long-term investment and/or  current income  objectives, you can  choose one  of
several  TFM investment strategies. Based on  your chosen strategy, your initial
investment will be allocated among a number of the Class A or Class B shares  of
the  portfolios. Depending  on market  conditions, the  TFM Adviser periodically
reallocates the combination of portfolios or the percentage amounts invested  in
the  shares  of each  portfolio to  implement your  TFM investment  strategy. In
addition, your TFM Account will be periodically rebalanced to maintain your  TFM
strategy's  current asset allocation mix, if and  when the performance of one or
more of  the portfolios  unbalances the  strategy's mix.  You will  pay the  TFM
Adviser  a fee for the  TFM Account service that is  in addition to and separate
from the fees and expenses you will pay directly or indirectly as an investor in
the portfolios. See "Fund Expenses."
    
 
   
    From time to time, one or more of the portfolios used for investment by  the
TFM  Accounts may experience relatively large  investments or redemptions due to
the TFM  Account allocations  or rebalancings  recommended by  the TFM  Adviser.
These  transactions will affect the portfolios, since portfolios that experience
redemptions as  a result  of  reallocations or  rebalancings  may have  to  sell
portfolio  securities and portfolios  that receive additional  cash will have to
invest it in additional portfolio securities. While it is impossible to  predict
the  overall  impact of  these transactions  over time,  there could  be adverse
effects on portfolio management to the extent that portfolios may be required to
sell securities or invest  cash at times  when they would  not otherwise do  so.
These  transactions  could also  have tax  consequences  if sales  of securities
resulted in gains and could also increase
    
 
                                       22
<PAGE>
   
transaction costs. The Adviser, representing the interests of the portfolios, is
committed  to  minimizing  the  impact  of  TFM  Account  transactions  on   the
portfolios.  The  Adviser,  however, will  have  a conflict  in  fulfilling this
responsibility in that it also  serves as a TFM  Adviser. In that capacity,  the
Adviser,  representing the interests  of the TFM Accounts,  also is committed to
minimizing the  impact of  TFM Account  transactions on  the portfolios  to  the
extent  consistent with pursuing the investment  objectives of the TFM Accounts.
In addition, an affiliate of the TFM Adviser, the Distributor is compensated  on
the  sale,and may be compensated for distribution or shareholder services on the
sale of shares  of the  portfolios. See  "Purchase of  Shares" and  "Shareholder
Services  --  Exchange Features."  The Adviser  will monitor  the impact  of TFM
Account transactions on the Portfolios.
    
 
                              REDEMPTION OF SHARES
 
    You may  withdraw all  or  any portion  of the  amount  in your  account  by
redeeming  shares at any time. Please note  that purchases made by check are not
permitted to be redeemed until payment of the purchase price has been collected,
which may take up to  eight business days after  purchase. The Fund will  redeem
Class  A shares or  Class B shares of  the Portfolio at  the next determined net
asset value of shares of  the applicable class. On days  that both the NYSE  and
the  Custodian Bank are open for business, the  net asset value per share of the
Portfolio is determined at the close of trading of the NYSE (currently 4:00 p.m.
Eastern Time). Shares of the Portfolio may be redeemed by mail or telephone.  No
charge  is made for redemption. Any redemption proceeds may be more or less than
the purchase price of your shares depending on, among other factors, the  market
value of the investment securities held by the Portfolio.
 
BY MAIL
 
    The  Portfolio will redeem its  Class A shares or Class  B shares at the net
asset value determined on the  date the request is  received, if the request  is
received  in "good  order" before  the regular close  of the  NYSE. Your request
should be addressed to Morgan Stanley  Institutional Fund, Inc., P.O. Box  2798,
Boston,  Massachusetts 02208-2798,  except that deliveries  by overnight courier
should be addressed to Morgan Stanley Institutional Fund, Inc., c/o Chase Global
Funds Services Company, 73 Tremont Street, Boston, Massachusetts 02108-3913.
 
    "Good order"  means that  the  request to  redeem  shares must  include  the
following documentation:
 
        (a)   A letter of instruction or a stock assignment specifying the class
    and number  of  shares  or dollar  amount  to  be redeemed,  signed  by  all
    registered  owners  of the  shares  in the  exact  names in  which  they are
    registered;
 
        (b)  Any  required   signature  guarantees   (see  "Further   Redemption
    Information" below); and
 
        (c)    Other supporting  legal documents,  if required,  in the  case of
    estates, trusts,  guardianships, custodianships,  corporations, pension  and
    profit-sharing plans and other organizations.
 
    Shareholders who are uncertain of requirements for redemption should consult
with a Morgan Stanley Institutional Fund representative.
 
BY TELEPHONE
 
    Provided  you have previously elected the Telephone Redemption Option on the
Account Registration  Form, you  can  request a  redemption  of your  shares  by
calling the Fund and requesting the redemption proceeds
 
                                       23
<PAGE>
be  mailed  to you  or wired  to your  bank.  Please contact  one of  the Fund's
representatives for further details. In times of drastic market conditions,  the
telephone  redemption option  may be difficult  to implement.  If you experience
difficulty in making a telephone redemption, your request may be made by mail or
express mail and  will be  implemented at the  net asset  value next  determined
after  it is received. Redemption requests sent to the Fund through express mail
must be mailed  to the  address of the  Dividend Disbursing  and Transfer  Agent
listed  under "General Information." The Fund and the Fund's transfer agent (the
"Transfer  Agent")  will  employ  reasonable  procedures  to  confirm  that  the
instructions  communicated by  telephone are  genuine. These  procedures include
requiring the investor to provide certain personal identification information at
the time an account is opened and prior to effecting each transaction  requested
by  telephone. In addition, all telephone  transaction requests will be recorded
and  investors  may  be  required  to  provide  additional  telecopied   written
instructions  regarding transaction requests. Neither  the Fund nor the Transfer
Agent will be responsible for any loss, liability, cost or expense for following
instructions received by telephone that either of them reasonably believes to be
genuine.
 
    To change the commercial  bank or account  designated to receive  redemption
proceeds,  a written  request must  be sent  to the  Fund at  the address above.
Requests to change the bank  or account must be  signed by each shareholder  and
each signature must be guaranteed.
 
FURTHER REDEMPTION INFORMATION
 
    Normally  the  Fund will  make payment  for all  shares redeemed  within one
business day of receipt  of the request,  but in no event  will payment be  made
more  than  seven days  after receipt  of  a redemption  request in  good order.
However, payments to investors  redeeming shares which  were purchased by  check
will  not be made until  payment for the purchase  has been collected, which may
take up to eight days after the date of purchase. The Fund may suspend the right
of redemption or postpone the date upon which redemptions are effected at  times
when  the NYSE is closed, or under  any emergency circumstances as determined by
the Securities and Exchange Commission (the "Commission").
 
    If the Board  of Directors determines  that it would  be detrimental to  the
best  interests of the  remaining shareholders of the  Portfolio to make payment
wholly or partly in cash, the Fund  may pay the redemption proceeds in whole  or
in part by a distribution in-kind of securities held by the Portfolio in lieu of
cash    in    conformity   with    applicable    rules   of    the   Commission.
Distributions-in-Kind will be made in readily marketable securities.
 
    To protect  your account,  the Fund  and its  agents from  fraud,  signature
guarantees  are required for  certain redemptions to verify  the identity of the
person who has  authorized a redemption  from your account.  Please contact  the
Fund for further information.
 
                              SHAREHOLDER SERVICES
 
EXCHANGE FEATURES
 
    You  may exchange  shares that you  own in  the Portfolio for  shares of any
other available portfolio(s) of  the Fund (other  than the International  Equity
Portfolio,  which is  closed to  new investors). In  exchanging for  shares of a
portfolio with more  than one  class, the  class of  shares you  receive in  the
exchange  will be determined in the same  manner as any other purchase of shares
and will not  be based  on the  class of  shares surrendered  for the  exchange.
Consequently,  the same minimum initial investment  and minimum account size for
determining the
 
                                       24
<PAGE>
class of shares received in the  exchange will apply. See "Purchase of  Shares."
Shares of the portfolios may be exchanged by mail or telephone. The privilege to
exchange shares by telephone is automatic and made available without shareholder
election.  Before you make  an exchange, you  should read the  prospectus of the
portfolio(s) in which  you seek to  invest. Because an  exchange transaction  is
treated  as a redemption followed by a purchase, an exchange would be considered
a taxable event for shareholders subject to tax. The exchange privilege is  only
available  with  respect  to  portfolios  that  are  registered  for  sale  in a
shareholder's state  of residence.  The exchange  privilege may  be modified  or
terminated by the Fund at any time upon 60-days notice to shareholders.
 
BY MAIL
 
    In  order to  exchange shares  by mail, you  should include  in the exchange
request the name, class of shares and account number of your current  Portfolio,
the name(s) of the portfolio(s) and class(es) of shares into which you intend to
exchange  shares, and the signatures of all registered account holders. Send the
exchange request  to Morgan  Stanley Institutional  Fund, Inc.,  P.O. Box  2798,
Boston, MA 02208-2798.
 
BY TELEPHONE
 
   
    When  exchanging shares by  telephone, have ready the  name, class of shares
and account number of the current  portfolio, the names of the portfolio(s)  and
class(es)  of  shares into  which  you intend  to  exchange shares,  your Social
Security number  or Tax  I.D. number,  and your  account address.  Requests  for
telephone  exchanges received prior to 4:00 p.m. (Eastern Time) are processed at
the close of business that same day based on the net asset value of the class of
the portfolios involved  in the  exchange of shares  at the  close of  business.
Requests  received after 4:00 p.m. are processed  the next business day based on
the net  asset value  determined  at the  close of  business  on such  day.  For
additional   information  regarding  responsibility   for  the  authenticity  of
telephoned instructions, see "Redemption of Shares -- By Telephone" above.
    
 
TRANSFER OF REGISTRATION
 
    You may transfer the registration of any of your Portfolio shares to another
person by writing  to Morgan Stanley  Institutional Fund, Inc.,  P.O. Box  2798,
Boston,  Massachusetts 02208-2798.  As in the  case of  redemptions, the written
request must  be  received  in good  order  before  any transfer  can  be  made.
Transferring  the  registration of  shares may  affect  the eligibility  of your
account for  a  given  class  of  the  Portfolio's  shares  and  may  result  in
involuntary  conversion or redemption  of your shares.  See "Purchase of Shares"
above.
 
                              VALUATION OF SHARES
 
    The net asset  value per  share of  a class of  shares of  the Portfolio  is
determined by dividing the total market value of the Portfolio's investments and
other  assets attributable to  such class, less  any liabilities attributable to
such class, by  the total  number of  outstanding shares  of each  class of  the
Portfolio.  Net  asset value  is  calculated separately  for  each class  of the
Portfolio. Net asset value per share is  determined as of the close of the  NYSE
on  each day  that the NYSE  is open  for business. Price  information on listed
securities is taken from  the exchange where the  security is primarily  traded.
Securities  listed on a U.S. securities exchange for which market quotations are
available are valued at the last quoted  sale price on the day the valuation  is
made. Securities listed on a foreign exchange are valued at their closing price.
Unlisted  securities and listed securities not  traded on the valuation date for
which market quotations  are readily  available are valued  at a  price that  is
considered to best
 
                                       25
<PAGE>
   
represent  fair value within a  range not exceeding the  current asked price nor
less than the current bid  price. The current average  bid and asked prices  are
determined  based on the bid  and asked prices quoted  on such valuation date by
reputable brokers.
    
 
    Bonds and other fixed income securities are valued according to the broadest
and most representative  market, which will  ordinarily be the  over-the-counter
market.  Net asset value includes interest  on fixed income securities, which is
accrued daily.  In addition,  bonds and  other fixed  income securities  may  be
valued on the basis of prices provided by a pricing service when such prices are
believed  to  reflect  the fair  market  value  of such  securities.  The prices
provided by a pricing service are determined without regard to bid or last  sale
prices,  but take into account institutional  size, trading in similar groups of
securities and any developments related  to the specific securities.  Securities
not  priced in this manner are valued at  the most recently quoted bid price or,
when securities exchange valuations are used, at the latest quoted sale price on
the day of valuation. If there is  no such reported sale, the latest quoted  bid
price will be used. Securities purchased with remaining maturities of 60 days or
less are valued at amortized cost, if it approximates market value. In the event
that  amortized  cost  does  not  approximate  market  value,  market  prices as
determined above will be used.
 
   
    The value  of other  assets  and securities  for  which quotations  are  not
readily  available (including  restricted and  unlisted foreign  securities) and
those securities for which it is inappropriate to determine prices in accordance
with the above-stated procedure are determined in good faith at fair value using
methods determined by the  Board of Directors. For  purposes of calculating  net
asset value per share, all assets and liabilities initially expressed in foreign
currencies will be translated into U.S. dollars at the mean of the bid and asked
price of such currencies against the U.S. dollar last quoted by any major bank.
    
 
    Although  the legal rights of Class A  and Class B shares will be identical,
the different expenses borne  by each class will  result in different net  asset
values  and dividends for the class.  Dividends will differ by approximately the
amount of the distribution expense  accrual differential among the classes.  The
net  asset value of  Class B shares will  generally be lower  than the net asset
value of the Class A shares as  a result of the distribution expense charged  to
Class B shares.
 
                            PERFORMANCE INFORMATION
 
    The  Fund may from time to time advertise total return for each class of the
Portfolio. THESE FIGURES ARE BASED ON  HISTORICAL EARNINGS AND ARE NOT  INTENDED
TO INDICATE FUTURE PERFORMANCE.
 
    The Portfolio may advertise "total return" which shows what an investment in
a class of the Portfolio would have earned over a specified period of time (such
as one, five or ten years), assuming that all distributions and dividends by the
Portfolio were reinvested in the same class on the reinvestment dates during the
period.  Total return  does not  take into account  any federal  or state income
taxes that may be payable on  dividends and distributions or on redemption.  The
Fund  may  also include  comparative performance  information in  advertising or
marketing  the  Portfolio's  shares,  including  data  from  Lipper   Analytical
Services,  Inc.,  other  industry  publications,  business  periodicals,  rating
services and market indices.
 
    The performance figures  for Class  B shares  will generally  be lower  than
those  for Class  A shares because  of the  distribution fee charged  to Class B
shares.
 
                                       26
<PAGE>
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
 
    All income dividends and capital gains  distributions for a class of  shares
will be automatically reinvested in additional shares of such class at net asset
value,  except that,  upon written  notice to  the Fund  or by  checking off the
appropriate box in the Distribution  Option Section on the Account  Registration
Form,  a shareholder  may elect  to receive  income dividends  and capital gains
distributions in cash.
 
   
    The Portfolio expects  to distribute  substantially all of  its taxable  net
investment  income in the form of  annual dividends. Net realized capital gains,
if any, after reduction  for any available tax  loss carryforwards will also  be
distributed annually.
    
 
    Undistributed  net  investment income  is  included in  the  Portfolio's net
assets for the purpose of calculating  net asset value per share. Therefore,  on
the  "ex-dividend" date,  the net  asset value  per share  excludes the dividend
(i.e., is  reduced by  the per  share amount  of the  dividend). Dividends  paid
shortly after the purchase of shares by an investor, although in effect a return
of capital, are taxable to shareholders subject to income tax.
 
    Because  of  the  distribution  fee  and  any  other  expenses  that  may be
attributable to  the Class  B shares,  the net  income attributable  to and  the
dividends  payable  on  Class  B  shares  will  be  lower  than  the  net income
attributable to and the dividends  payable on Class A  shares. As a result,  the
net  asset value per share of the classes of the Portfolio will differ at times.
Expenses of the  Portfolio allocated  to a particular  class of  shares will  be
borne on a pro rata basis by each outstanding share of that class.
 
                                     TAXES
 
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
 
    No  attempt has been made to present  a detailed explanation of the federal,
state, or  local income  tax treatment  of the  Portfolio or  its  shareholders.
Accordingly,  shareholders  are urged  to consult  their tax  advisors regarding
specific questions as to federal, state and local income taxes.
 
    The Portfolio  is  treated as  a  separate  entity for  federal  income  tax
purposes  and is  not combined with  the Fund's other  portfolios. The Portfolio
intends to qualify for the  special tax treatment afforded regulated  investment
companies under Subchapter M of the Code, so that the Portfolio will be relieved
of  federal income tax on that part of its net investment income and net capital
gain that is distributed to shareholders.
 
   
    The Portfolio intends  to distribute  substantially all of  its taxable  net
investment  income (including, for this purpose, net short-term capital gain) to
shareholders. Dividends from the Portfolio's  net investment income are  taxable
to  shareholders as ordinary  income, whether received in  cash or reinvested in
additional shares.  Such dividends  paid  by the  Portfolio will  generally  not
qualify for the 70% dividends-received deduction for corporate shareholders. The
Portfolio will report annually to its shareholders the amount of dividend income
qualifying for such treatment.
    
 
    Distributions  of  net capital  gain (i.e.,  net  long-term capital  gain in
excess of  net  short-term  capital  losses)  are  taxable  to  shareholders  as
long-term  capital gain,  regardless of  how long  the shareholder  has held the
Portfolio's shares. The Portfolio will send reports annually to shareholders  of
the  federal income  tax status of  all distributions made  during the preceding
year.
 
                                       27
<PAGE>
    The  Portfolio   intends  to   make  sufficient   distributions  or   deemed
distributions  of its ordinary income and capital gain net income (the excess of
short-term and  long-term capital  gain over  short-term and  long-term  capital
loss,  including any available  capital loss carryforwards) prior  to the end of
each calendar year to avoid liability for federal excise tax.
 
    Dividends and  other distributions  declared by  the Portfolio  in  October,
November or December of any year and payable to shareholders of record on a date
in  such month will be deemed to have been paid by the Portfolio and received by
the shareholders in that year if the distributions are paid by the Portfolio  at
any time during the following January.
 
    The  Fund may be required to withhold and  remit to the U.S. Treasury 31% of
any taxable dividends, capital gains distributions and redemption proceeds  paid
to  any individual or certain other non-corporate shareholder (1) who has failed
to provide a correct taxpayer  identification number (generally an  individual's
social  security number  or non-individual's employer  identification number) on
the Application Form, (2) who is  subject to backup withholding by the  Internal
Revenue  Service, or (3) who has not certified to the Fund that such shareholder
is not  subject  to  backup  withholding. This  backup  withholding  is  not  an
additional   tax,  and  any  amounts  withheld   may  be  credited  against  the
shareholder's ultimate U.S. tax liability.
 
    The sale, exchange or  redemption of shares will  result in taxable gain  or
loss to the selling, exchanging or redeeming shareholder, depending upon whether
the fair market value of the sale, exchange or redemption proceeds exceed or are
less  than the shareholder's  adjusted basis in the  sold, exchanged or redeemed
shares. If capital gain distributions have been made with respect to shares that
are sold at a  loss after being held  for six months or  less, then the loss  is
treated  as  a  long-term  capital  loss  to  the  extent  of  the  capital gain
distributions.
 
    Conversion  of  shares  between  classes  are  not  taxable  events  to  the
shareholder.
 
    Shareholders  are urged  to consult with  their tax  advisers concerning the
application of state  and local income  taxes to investments  in the  Portfolio,
which may differ from the federal income tax consequences described above.
 
    Investment  income  received by  the Portfolio  from sources  within foreign
countries may be subject to foreign income taxes withheld at the source. To  the
extent  that the Portfolio is  liable for foreign income  taxes so withheld, the
Portfolio intends to operate so as to meet the requirements of the Code to  pass
through  to the shareholders credit for  foreign income taxes paid. Although the
Portfolio intends to  meet Code  requirements to  pass through  credit for  such
taxes, there can be no assurance that the Portfolio will be able to do so.
 
    THE TAX DISCUSSION SET FORTH ABOVE IS INCLUDED FOR GENERAL INFORMATION ONLY.
PROSPECTIVE  INVESTORS SHOULD CONSULT THEIR OWN TAX ADVISERS WITH RESPECT TO THE
TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN THE PORTFOLIO.
 
                             PORTFOLIO TRANSACTIONS
 
    The Adviser selects the brokers or  dealers that will execute the  purchases
and  sales  of investment  securities  for each  of  the Fund's  portfolios. The
Adviser seeks the best execution of all portfolio transactions. A portfolio  may
pay  higher commission rates than the lowest available when the Adviser believes
it is reasonable to do  so in light of the  value of the research,  statistical,
and pricing services provided by the broker effecting the transaction.
 
                                       28
<PAGE>
    It is not the Fund's practice to allocate brokerage or principal business on
the  basis of sales of shares which  may be made through intermediary brokers or
dealers. However, the Adviser may,  consistent with NASD rules, place  portfolio
orders  with qualified broker-dealers who  recommend the applicable portfolio to
their clients or who act  as agents in the purchase  of shares of the  portfolio
for their clients.
 
    Subject  to  the overriding  objective of  obtaining  the best  execution of
orders, the  Fund may  use broker-dealer  affiliates of  the Adviser,  including
Morgan  Stanley,  to effect  portfolio  brokerage transactions  under procedures
adopted by the Fund's Board of Directors. For such transactions, the  commission
rates  and other remuneration paid to Morgan Stanley or other affiliates must be
fair  and  reasonable  in  comparison  to  those  of  other  broker-dealers  for
comparable  transactions involving  similar securities  being purchased  or sold
during a comparable time period.
 
PORTFOLIO TURNOVER
 
    The Portfolio generally  does not  invest for  short-term trading  purposes,
however,   when  circumstances  warrant,  the   Portfolio  may  sell  investment
securities without regard  to the  length of time  they have  been held.  Market
conditions  in a given year could result in a higher or lower portfolio turnover
rate than expected and the Portfolio will not consider portfolio turnover rate a
limiting factor in making investment decisions consistent with their  respective
objective   and  policies.  As  portfolio   turnover  increases,  the  Portfolio
necessarily  will  experience   increased  transaction   costs  and   additional
realization of capital gains.
 
                              GENERAL INFORMATION
 
DESCRIPTION OF COMMON STOCK
 
   
    The  Fund was  organized as  a Maryland  corporation on  June 16,  1988. The
Articles of Incorporation, as amended and restated, permit the Fund to issue  up
to  35 billion shares of common stock,  with $.001 par value per share. Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number of shares the  Fund is authorized  to issue without  the approval of  the
shareholders  of the Fund. The Board of Directors has the power to designate one
or more classes of  shares of common  stock and to  classify and reclassify  any
unissued shares with respect to such classes. The shares of common stock of each
portfolio  are currently classified into two classes, the Class A shares and the
Class B  shares,  except for  the  International  Small Cap,  Money  Market  and
Municipal Money Market Portfolios which offer only Class A shares.
    
 
   
    The shares of the Portfolio, when issued, will be fully paid, nonassessable,
fully  transferable and redeemable at the option  of the holder. The shares have
no preference  as  to  conversion,  exchange,  dividends,  retirement  or  other
features  and  have no  pre-emptive  rights. The  shares  of the  Portfolio have
non-cumulative voting rights, which means that  the holders of more than 50%  of
the  shares voting for the election of Directors can elect 100% of the Directors
if they choose  to do so.  Persons or organizations  owning 25% or  more of  the
outstanding  shares of a portfolio may be presumed to "control" (as that term is
defined in the 1940  Act) that portfolio.  Under Maryland law,  the Fund is  not
required  to hold an annual meeting of its shareholders unless required to do so
under the 1940 Act.
    
 
REPORTS TO SHAREHOLDERS
 
    The Fund will send to its  shareholders annual and semi-annual reports;  the
financial  statements  appearing in  annual reports  are audited  by independent
accountants. Monthly unaudited portfolio  data is also  available from the  Fund
upon request.
 
                                       29
<PAGE>
    In  addition, the Adviser or its agent, as Transfer Agent, will send to each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
 
CUSTODIAN
 
    Chase is the Fund's custodian for domestic and certain foreign assets. Chase
is not an  affiliate of  the Adviser or  the Distributor.  Morgan Stanley  Trust
Company,  Brooklyn,  New York  ("MSTC"),  an affiliate  of  the Adviser  and the
Distributor, acts as  the Fund's custodian  for assets held  outside the  United
States  and employs subcustodians approved by the Board of Directors of the Fund
in accordance with regulations of the Securities and Exchange Commission for the
purpose of providing  custodial services  for such  assets. MSTC  may also  hold
certain  domestic assets for  the Fund. For more  information on the custodians,
see "General Information -- Custody Arrangements" in the Statement of Additional
Information.
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
    Chase  Global   Funds  Services   Company,   73  Tremont   Street,   Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
 
INDEPENDENT ACCOUNTANTS
 
   
    Price  Waterhouse LLP  serves as  independent accountants  for the  Fund and
audits its annual financial statements.
    
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       30
<PAGE>
   MORGAN STANLEY INSTITUTIONAL FUND, INC.
          ACTIVE COUNTRY ALLOCATION PORTFOLIO
           P.O. BOX 2798, BOSTON, MA 02208-2798
 
                           ACCOUNT REGISTRATION FORM
 
<TABLE>
<C>   <S>                                                           <C>
                                                                    If you need assistance in filling out this form for the
      ACCOUNT INFORMATION                                           Morgan Stanley Institutional Fund, please contact your
      Fill in where applicable                                      Morgan Stanley representative or call us toll free
                                                                    1-(800)-548-7786. Please print all items except signature,
                                                                    and mail to the Fund at the address above.
  A)  REGISTRATION
      1. INDIVIDUAL
      2. JOINT TENANTS
         (RIGHTS OF SURVIVORSHIP PRESUMED UNLESS
         TENANCY IN COMMON
         IS INDICATED)
</TABLE>
 
1.
                  First Name                  Initial                  Last Name
2.
                  First Name                  Initial                  Last Name
                  First Name                  Initial                  Last Name
 
<TABLE>
<C>   <S>                                       <C>
      3. CORPORATIONS,
         TRUSTS AND OTHERS
         Please call the Fund for additional
      documents that may be required to set up
      account and to authorize transactions.
</TABLE>
 
3.
 
<TABLE>
<S>                     <C>                 <C>                   <C>               <C>
Type of Registration:   / / INCORPORATED    / / UNINCORPORATED    / / PARTNERSHIP   / / UNIFORM GIFT/TRANSFER TO MINOR
                                            ASSOCIATION                               (ONLY ONE CUSTODIAN AND MINOR PERMITTED)
</TABLE>
 
/ / TRUST ________________________  / / OTHER (Specify) ________________________
 
<TABLE>
<C>   <S>                                            <C>
  B)  MAILING ADDRESS
      Please fill in completely, including
      telephone number(s).
</TABLE>
 
/ / United States Citizen  / / Resident Alien
                   Street or P.O. Box
                   City
                   State                   Zip
Home Telephone No.                   Business Telephone No.
/ / Non-Resident Alien:
Permanent Address (Where you reside permanently for tax purposes)
                   Street Address
                   City
                   Country                   Postal Code
Home Telephone No.                    Business Telephone No.
Current Mailing Address (If different from Permanent Address)
                   Street Address
                   City
                   Country
Postal Code
Home Telephone No.                   Business Telephone No.
 
<TABLE>
<C>   <S>                                            <C>                                  <C>
  C)  TAXPAYER                                       Enter   your  Taxpayer   Identification  Number.   For  most  individual
      IDENTIFICATION                                 taxpayers, this is your Social Security Number.
      NUMBER
      1. INDIVIDUAL
      2. JOINT TENANTS
         (RIGHTS OF SURVIVORSHIP PRESUMED UNLESS
         TENANCY IN COMMON
         IS INDICATED)
      For Custodian account
      of a minor (Uniform
      Gifts/Transfers to Minor
      Acts), give the Social
      Security Number of
      the minor
                                                                                          OR
                                                     1.         TAXPAYER IDENTIFICATION   SOCIAL SECURITY NUMBER
                                                     NUMBER ("TIN")                       ("SSN")
                                                                                          OR
                                                     2.         TIN                       SSN
                                                                                          OR
                                                     TIN                                  SSN
                                                     IMPORTANT TAX INFORMATION
                                                     You (as a payee) are required by law to provide us (as payer) with  your
                                                     correct  TIN(s) or  SSN(s). Accounts  that have  a missing  or incorrect
                                                     TIN(s) or SSN(s) will be subject to backup withholding at a 31% rate  on
                                                     dividends, distributions and other payments. If you have not provided us
                                                     with  your correct TIN(s) or SSN(s), you may be subject to a $50 penalty
                                                     imposed by the Internal Revenue Service.
                                                     Backup withholding  is  not an  additional  tax; the  tax  liability  of
                                                     persons  subject to backup withholding will  be reduced by the amount of
                                                     tax withheld.  If withholding  results  in an  overpayment of  taxes,  a
                                                     refund may be obtained.
                                                     You  may be  notified that you  are subject to  backup withholding under
                                                     Section 3406(a)(1)(C)  of the  Internal Revenue  Code because  you  have
                                                     underreported  interest or dividends or you were required to, but failed
                                                     to, file a  return which would  have included a  reportable interest  or
                                                     dividend payment.
</TABLE>
 
<PAGE>
 
   
<TABLE>
<C>   <S>                        <C>                             <C>                   <C>
  D)  PORTFOLIO AND              For Purchase of the following
      CLASS SECTION              Portfolio(s):                   / / Class A Shares $  / / Class B Shares $
      (Class A shares minimum    Active Country Allocation
      $500,000 for the           Portfolio
      Portfolio and Class B
      shares minimum $100,000
      for the Portfolio).
      Please indicate class and
      amount.
                                                                 Total Initial Investment $
</TABLE>
    
 
<TABLE>
<C>   <S>                        <C>
  E)  METHOD OF
      INVESTMENT
      Please indicate
      portfolio, manner of
      payment.
</TABLE>
 
Payment by:
 
/ / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND,
INC.--PORTFOLIO NAME)
 
<TABLE>
<S>                                                                                 <C>
/ / Exchange $ From                                                                           -- - - - - - - - - - -- - -
                                                      Name of Portfolio                               Account No.
/ / Account previously established by:  / / Phone exchange  / / Wire on                       -- - - - - - - - - - -- - -
                                                                                            Account No.               (Check
                                                                                      (Previously assigned by the Fund)     Digit)
                                                                            Date
</TABLE>
 
<TABLE>
<C>   <S>                        <C>
  F)  DISTRIBUTION               Income dividends and capital gains distributions (if any) to
      OPTION                     be reinvested in additional shares unless either box below
                                 is checked.
                                 / / Income dividends to be paid in cash, capital gains
                                 distributions (if any) in shares.
                                 / / Income dividends and capital gains distributions (if
                                 any) to be paid in cash.
</TABLE>
 
<TABLE>
<C>   <S>                             <C>                                       <C>
  G)  TELEPHONE                       / / I/we hereby authorize the Fund and
      REDEMPTION                      its agents to honor any telephone         Name of COMMERCIAL Bank (Not Savings
      AND EXCHANGE                    requests to wire redemption proceeds to   Bank)
      OPTION                          the commercial bank indicated at right    Bank Account No.
      Please select at time of        and/or mail redemption proceeds to the
      initial application if you      name and address in which my/our fund
      wish to redeem or exchange      account is registered if such requests                                        Bank
      shares by telephone. A          are believed to be authentic.                                                  ABA
      SIGNATURE GUARANTEE IS          The Fund and the Fund's Transfer Agent                                         No.
      REQUIRED IF BANK ACCOUNT IS     will employ reasonable procedures to
      NOT REGISTERED IDENTICALLY TO   confirm that instructions communicated    Name(s) in which your BANK Account is
      YOUR FUND ACCOUNT.              by telephone are genuine. These           Established
      TELEPHONE REQUESTS FOR          procedures include requiring the
      REDEMPTIONS OR EXCHANGE WILL    investor to provide certain personal      Bank's Street
      NOT BE HONORED UNLESS THE BOX   identification information at the time    Address
      IS CHECKED.                     an account is opened and prior to
                                      effecting each transaction requested by   City                   State                   Zip
                                      telephone. In addition, all telephone
                                      transaction requests will be recorded
                                      and investors may be required to provide
                                      additional telecopied written
                                      instructions of transaction requests.
                                      Neither the Fund nor the Transfer Agent
                                      will be responsible for any loss,
                                      liability, cost or expense for following
                                      instructions received by telephone that
                                      it reasonably believes to be genuine.
</TABLE>
 
   
<TABLE>
<C>   <S>                        <C>
  H)  INTERESTED PARTY
      OPTION                                                                                      Name
      In addition to the
      account statement sent to
      my/our registered                                                                          Address
      address, I/we hereby
      authorize the Fund to      City         State         Zip Code
      mail duplicate statements
      to the name and address
      provided at right.
</TABLE>
    
 
<TABLE>
<C>   <S>                        <C>
  I)  DEALER
      INFORMATION
                                 Representative Name                        Representative
                                 No.                            Branch
                                 No.
</TABLE>
 
<PAGE>
 
<TABLE>
<C>   <S>                        <C>
  J)  SIGNATURE OF
      ALL HOLDERS
      AND TAXPAYER
      CERTIFICATION
      Sign Here ,
</TABLE>
 
<TABLE>
<S>                                  <C>
The undersigned certify that I/we have full authority and legal capacity
to purchase and redeem shares of the Fund and affirm that I/we have
received a current Prospectus of the Morgan Stanley Institutional Fund,
Inc. and agree to be bound by its terms.
  BY  SIGNING THIS APPLICATION,  I/WE HEREBY CERTIFY  UNDER PENALTIES OF
PERJURY THAT THE INFORMATION ON THIS APPLICATION IS COMPLETE AND CORRECT
AND THAT  AS REQUIRED  BY  FEDERAL LAW  (PLEASE CHECK  APPLICABLE  BOXES
BELOW):
/ / U.S. CITIZEN(S)/TAXPAYER(S):
       /  / I/WE CERTIFY THAT (1) THE NUMBER(S) SHOWN ABOVE ON THIS FORM
           IS/ARE THE  CORRECT SSN(S)  OR TIN(S)  AND (2)  I/WE ARE  NOT
           SUBJECT TO ANY BACKUP WITHHOLDING EITHER BECAUSE (A) I/WE ARE
           EXEMPT  FROM  BACKUP  WITHHOLDING;  (B)  I/WE  HAVE  NOT BEEN
           NOTIFIED BY THE  INTERNAL REVENUE SERVICE  ("IRS") THAT  I/WE
           ARE SUBJECT TO BACKUP WITHHOLDING AS A RESULT OF A FAILURE TO
           REPORT ALL INTEREST OR DIVIDENDS; OR (C) THE IRS HAS NOTIFIED
           ME/US   THAT  I  AM/WE  ARE   NO  LONGER  SUBJECT  TO  BACKUP
           WITHHOLDING.
       / / IF  NO TIN(S) OR  SSN(S) HAS/HAVE BEEN  PROVIDED ABOVE,  I/WE
           HAVE  APPLIED, OR INTEND  TO APPLY, TO THE  IRS OR THE SOCIAL
           SECURITY  ADMINISTRATION  FOR  A  TIN  OR  A  SSN  AND   I/WE
           UNDERSTAND THAT IF I/WE DO NOT PROVIDE EITHER NUMBER TO CHASE
           GLOBAL FUNDS SERVICES COMPANY ("CGFSC") WITHIN 60 DAYS OF THE
           DATE  OF THIS APPLICATION  OR IF I/WE  FAIL TO FURNISH MY/OUR
           CORRECT SSN(S) OR TIN(S),  I/WE MAY BE  SUBJECT TO A  PENALTY
           AND  A 31% BACKUP WITHHOLDING ON DISTRIBUTIONS AND REDEMPTION
           PROCEEDS. (PLEASE PROVIDE EITHER NUMBER ON IRS FORM W-9). YOU
           MAY REQUEST SUCH FORM BY CALLING CGFSC AT 800-282-4404.
/ / NON-U.S. CITIZEN(S)/TAXPAYER(S)
UNDER PENALTIES OF PERJURY, I/WE CERTIFY THAT I/WE ARE NOT U.S. CITIZENS
OR RESIDENTS  AND I/WE  ARE EXEMPT  FOREIGN PERSONS  AS DEFINED  BY  THE
INTERNAL REVENUE SERVICE.
 
THE  INTERNAL  REVENUE  SERVICE DOES  NOT  REQUIRE YOUR  CONSENT  TO ANY
PROVISION OF THIS  DOCUMENT OTHER  THAN THE  CERTIFICATIONS REQUIRED  TO
AVOID BACKUP WITHHOLDING.
 
                                     (X)
(X)                                  Signature (if joint account, both
Signature                                                                     Date must sign)         Date
</TABLE>
<PAGE>
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
 
  NO  DEALER, SALES  REPRESENTATIVE OR ANY  OTHER PERSON HAS  BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE  CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS  HAVING BEEN AUTHORIZED BY THE FUND  OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF  THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION  TO
ANY  PERSON TO WHOM  IT IS UNLAWFUL TO  MAKE SUCH OFFER  OR SOLICITATION IN SUCH
JURISDICTION.
 
                           --------------------------
 
                               TABLE OF CONTENTS
 
   
<TABLE>
<S>                                                 <C>
                                                    PAGE
                                                    ----
Fund Expenses.....................................    2
Financial Highlights..............................    4
Prospectus Summary................................    6
Investment Objective and Policies.................   10
Additional Investment Information.................   12
Investment Limitations............................   15
Management of the Fund............................   16
Purchase of Shares................................   18
Redemption of Shares..............................   23
Shareholder Services..............................   24
Valuation of Shares...............................   25
Performance Information...........................   26
Dividends and Capital Gains Distributions.........   27
Taxes.............................................   27
Portfolio Transactions............................   28
General Information...............................   29
Account Registration Form
</TABLE>
    
 
                      ACTIVE COUNTRY ALLOCATION PORTFOLIO
 
                               A PORTFOLIO OF THE
 
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
 
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
 
- ---------------------------------
- ---------------------------------
- ---------------------------------
- ---------------------------------
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
     ----------------------------------------------------------------------
 
                                 GOLD PORTFOLIO
 
                               A PORTFOLIO OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
 
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
 
                                ----------------
 
   
    Morgan  Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company, or mutual fund, which offers redeemable shares in
a   series   of   diversified   and   non-diversified   investment    portfolios
("portfolios").  The  Fund  is  designed  to  provide  clients  with  attractive
alternatives for meeting their investment needs. The Fund currently consists  of
twenty-nine  portfolios representing a  broad range of  investment choices. This
prospectus (the "Prospectus") pertains to the Class A and the Class B shares  of
the  Gold Portfolio (the "Portfolio"). The Class  A and Class B shares currently
offered by the Portfolio have different minimum investment requirements and fund
expenses. Shares of the  portfolios are offered with  no sales charge,  exchange
fee  or redemption fee,  (except that the International  Small Cap Portfolio may
impose a transaction fee).
    
 
   
    The Fund is designed  to meet the investment  needs of discerning  investors
who  place a premium on quality and  personal service. With Morgan Stanley Asset
Management  Inc.  as   Adviser  and   Administrator  (the   "Adviser"  and   the
"Administrator"),  and with Morgan Stanley & Co. Incorporated ("Morgan Stanley")
as Distributor, the  Fund makes available  to institutional and  high net  worth
individual  investors a series  of portfolios which  benefit from the investment
expertise and commitment to  excellence associated with  Morgan Stanley and  its
affiliates.
    
 
   
    This Prospectus is designed to set forth concisely the information about the
Fund  that a prospective investor should know  before investing and it should be
retained for future reference. The  Fund offers additional portfolios which  are
described  in other prospectuses and under  "Prospectus Summary" below. The Fund
currently offers the following portfolios:  (i) GLOBAL AND INTERNATIONAL  EQUITY
- --  Active Country Allocation, Asian  Equity, Emerging Markets, European Equity,
Global Equity, Gold, International  Equity, International Magnum,  International
Small  Cap, Japanese Equity  and Latin American Portfolios;  (ii) U.S. EQUITY --
Aggressive Equity,  Emerging  Growth, Equity  Growth,  Small Cap  Value  Equity,
Technology, U.S. Real Estate and Value Equity Portfolios; (iii) EQUITY AND FIXED
INCOME  -- Balanced Portfolio; (iv) FIXED INCOME -- Emerging Markets Debt, Fixed
Income, Global Fixed Income, High Yield  and Municipal Bond Portfolios; and  (v)
MONEY  MARKET -- Money Market and  Municipal Money Market Portfolios. Additional
information  about  the  Fund  is  contained  in  a  "Statement  of   Additional
Information,"  dated May 1, 1997, which is incorporated herein by reference. The
Statement of Additional Information and the prospectuses pertaining to the other
portfolios of the Fund are available upon request and without charge by  writing
or calling the Fund at the address and telephone number set forth above.
    
 
   
THESE  SECURITIES HAVE NOT BEEN APPROVED  OR DISAPPROVED BY THE SECURITIES AND
  EXCHANGE COMMISSION,  NOR  HAS  THE SECURITIES  AND  EXCHANGE  COMMISSION
     PASSED  UPON  THE  ACCURACY  OR  ADEQUACY  OF  THIS  PROSPECTUS. ANY
       REPRESENTATION  TO   THE   CONTRARY   IS   A   CRIMINAL   OFFENSE.
    
 
   
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1997.
    
<PAGE>
                                 FUND EXPENSES
 
    The  following table illustrates the expenses and fees that a shareholder of
the Gold Portfolio will incur:
   
<TABLE>
<CAPTION>
SHAREHOLDER TRANSACTION EXPENSES
- --------------------------------------------------------------------------------------------
<S>                                                                                           <C>
Maximum Sales Load Imposed on Purchases
  Class A...................................................................................       None
  Class B...................................................................................       None
Maximum Sales Load Imposed on Reinvested Dividends
  Class A...................................................................................       None
  Class B...................................................................................       None
Deferred Sales Load
  Class A...................................................................................       None
  Class B...................................................................................       None
Redemption Fees
  Class A...................................................................................       None
  Class B...................................................................................       None
Exchange Fees
  Class A...................................................................................       None
  Class B...................................................................................       None
 
<CAPTION>
 
ANNUAL FUND OPERATING EXPENSES
- --------------------------------------------------------------------------------------------
<S>                                                                                           <C>
 (AS A PERCENTAGE OF AVERAGE NET ASSETS)
Management Fee (Net of Fee Waiver)*
  Class A...................................................................................      0.52%
  Class B...................................................................................      0.52%
12b-1 Fees
  Class A...................................................................................       None
  Class B...................................................................................      0.25%
Other Expenses
  Class A...................................................................................      0.73%
  Class B...................................................................................      0.73%
                                                                                              ---------
  Total Operating Expenses (Net of Fee Waivers)*
  Class A...................................................................................      1.25%
  Class B...................................................................................      1.50%
                                                                                              ---------
                                                                                              ---------
</TABLE>
    
 
- ------------------------------
   
*The Adviser has  agreed to waive  its management fees  and/or to reimburse  the
 Portfolio,  if necessary, if  such fees would cause  the total annual operating
 expenses of the Portfolio  to exceed a specified  percentage of its  respective
 average  daily net assets. Absent  the fee waiver, the  management fee would be
 1.00%. Absent  the fee  waiver and/or  expense reimbursement,  the  Portfolio's
 total  operating expenses would be 1.73% of the average daily net assets of the
 Class A shares and 1.94% of the average daily net assets of the Class B shares.
 As a result of this  reduction, the Management Fee  stated above is lower  than
 the contractual fee stated under "Management of the Fund." The Adviser reserves
 the  right to terminate any of its fee waivers and/or expense reimbursements at
 any time in its sole discretion. For further information on Fund expenses,  see
 "Management of the Fund."
    
 
                                       2
<PAGE>
   
    The  purpose of the table  above is to assist  the investor in understanding
the various expenses  that an investor  in the Portfolio  will bear directly  or
indirectly.  Expenses and fees are  based on actual figures  for the fiscal year
ended December 31, 1996. Due to the  continuous nature of Rule 12b-1 fees,  long
term  Class  B shareholders  may pay  more  than the  equivalent of  the maximum
front-end sales  charges  otherwise permitted  by  the National  Association  of
Securities Dealers, Inc. ("NASD") Conduct Rules.
    
 
   
    The  following  example illustrates  the expenses  that you  would pay  on a
$1,000 investment assuming (1) a 5% annual rate of return and (2) redemption  at
the end of each time period. As noted above, the Portfolio charges no redemption
fees  of  any kind.  The example  is based  on total  operating expenses  of the
Portfolio after fee waivers.
    
 
   
<TABLE>
<CAPTION>
                                                                       1 YEAR       3 YEARS      5 YEARS     10 YEARS
                                                                     -----------  -----------  -----------  -----------
<S>                                                                  <C>          <C>          <C>          <C>
Gold Portfolio
  Class A..........................................................   $      13    $      40    $      69    $     151
  Class B..........................................................          15           47           82          179
</TABLE>
    
 
   
    THIS EXAMPLE SHOULD  NOT BE CONSIDERED  A REPRESENTATION OF  PAST OR  FUTURE
EXPENSES  OR  PERFORMANCE. ACTUAL  EXPENSES MAY  BE GREATER  OR LESS  THAN THOSE
SHOWN.
    
 
                                       3
<PAGE>
                              FINANCIAL HIGHLIGHTS
 
   
    The following table provides financial highlights for the Class A and  Class
B  shares  of the  Portfolio  for each  of  the periods  presented.  The audited
financial highlights  for  the  Portfolio's  shares  for  each  of  the  periods
presented are part of the Fund's financial statements which appear in the Fund's
December  31, 1996 Annual  Report to Shareholders and  which are incorporated by
reference in the  Fund's Statement  of Additional  Information. The  Portfolio's
financial  highlights for  each of  the periods  presented have  been audited by
Price Waterhouse LLP, whose unqualified  report thereon is also incorporated  by
reference  in the  Statement of  Additional Information.  Additional performance
information is  included  in  the  Annual Report.  The  Annual  Report  and  the
financial   statements  therein,   along  with   the  Statement   of  Additional
Information, are available at no cost from the Fund at the address and telephone
number noted on  the cover page  of this Prospectus.  The following  information
should be read in conjunction with the financial statements and notes thereto.
    
 
                                       4
<PAGE>
                                 GOLD PORTFOLIO
   
<TABLE>
<CAPTION>
                                                                                CLASS A
                                                    ---------------------------------------------------------------
                                                                                                    PERIOD FROM
                                                                                                 FEBRUARY 1, 1994*
                                                         YEAR ENDED            YEAR ENDED         TO DECEMBER 31,
                                                      DECEMBER 31, 1996     DECEMBER 31, 1995          1994
                                                    ---------------------   -----------------   -------------------
<S>                                                 <C>                     <C>                 <C>
NET ASSET VALUE, BEGINNING OF PERIOD..............         $  8.55               $ 9.13         $         10.00
                                                           -------               ------                 -------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (Loss) (1)................            0.05                (0.07)                   0.03
  Net Realized and Unrealized Gain (Loss) on
   Investments++..................................            1.41                 1.22                   (0.88)
                                                           -------               ------                 -------
    Total from Investment Operations..............            1.46                 1.15                   (0.85)
                                                           -------               ------                 -------
DISTRIBUTIONS
  Net Investment Income...........................           (0.05)               (0.01)                  (0.02)
  In Excess of Net Investment Income..............           (0.01)                  --                      --
  Net Realized Gain...............................              --                   --                   (1.72)
  In Excess of Net Realized Gain..................           (0.65)                  --                      --
                                                           -------               ------                 -------
    Total Distributions...........................           (0.71)               (1.73)                  (0.02)
                                                           -------               ------                 -------
NET ASSET VALUE, END OF PERIOD....................         $  9.30               $ 8.55         $          9.13
                                                           -------               ------                 -------
                                                           -------               ------                 -------
TOTAL RETURN......................................           16.94%               13.21%                  (8.49)%
                                                           -------               ------                 -------
                                                           -------               ------                 -------
RATIO AND SUPPLEMENTAL DATA:
  Net Assets, End of Period (Thousands)...........         $27,810               $7,409         $        30,243
  Ratio of Expenses to Average Net Assets (1).....            1.25%**              1.25%                   1.25%
  Ratio of Net Investment Income (Loss) to Average
   Net Assets (1).................................            0.57%               (0.31)%                  0.41%**
  Portfolio Turnover Rate.........................              94%                  47%                     56%
  Average Commission Rate#........................         $0.0246                  N/A                     N/A
 
<CAPTION>
                                                          CLASS B
                                                    -------------------
                                                        PERIOD FROM
                                                    JANUARY 2, 1996***
                                                      TO DECEMBER 31,
                                                           1996
                                                    -------------------
<S>                                                 <C>
NET ASSET VALUE, BEGINNING OF PERIOD..............  $          8.81
                                                            -------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (Loss) (1)................             0.03
  Net Realized and Unrealized Gain (Loss) on
   Investments++..................................             1.14
                                                            -------
    Total from Investment Operations..............             1.17
                                                            -------
DISTRIBUTIONS
  Net Investment Income...........................            (0.04)
  In Excess of Net Investment Income..............            (0.01)
  Net Realized Gain...............................               --
  In Excess of Net Realized Gain..................            (0.65)
                                                            -------
    Total Distributions...........................            (0.70)
                                                            -------
NET ASSET VALUE, END OF PERIOD....................  $          9.28
                                                            -------
                                                            -------
TOTAL RETURN......................................            13.21%
                                                            -------
                                                            -------
RATIO AND SUPPLEMENTAL DATA:
  Net Assets, End of Period (Thousands)...........  $         1,370
  Ratio of Expenses to Average Net Assets (1).....             1.50%**
  Ratio of Net Investment Income (Loss) to Average
   Net Assets (1).................................             0.30%**
  Portfolio Turnover Rate.........................               94%
  Average Commission Rate#........................          $0.0246
</TABLE>
    
 
- ------------------------------
 
   
<TABLE>
<C>  <S>                             <C>                     <C>                 <C>                   <C>
(1)  Effect of voluntary expense
      limitation during the period:
       Per share benefit to net
        investment income..........           $0.04                 $0.11                  $0.04                $0.04
     Ratios before expense
      limitation:
       Expenses to Average Net
        Assets.....................              1.73%               1.76%                  1.72%**              1.94%**
       Net Investment Loss to
        Average Net Assets.........              0.10     %         (0.82     )%           (0.06    )%**          (0.13     )%**
</TABLE>
    
 
   
  * Commencement of operations.
    
 
   
 ** Annualized.
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
   
 # Beginning  with fiscal year  1996, the Portfolio is  required to disclose the
   average commission rate  per share  it paid  for portfolio  trades, on  which
   commissions  were charged, during the period. For the year ended December 31,
   1996, the average commission  rate paid on trades  on which commissions  were
   charged was 0.47% of the trade amount.
    
 
   
 ++ The  amounts  shown  for  the  year ended  December  31,  1996  for  a share
    outstanding throughout the year does not accord with aggregate net losses on
    investments for the year because of  the timing of sales and repurchases  of
    the  portfolio  shares  in  relation  to  fluctuating  market  value  of the
    investments in the Portfolio.
    
 
                                       5
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
 
   
    The  Fund  consists  of   twenty-nine  portfolios,  offering   institutional
investors  and high net  worth individual investors a  broad range of investment
choices coupled with the advantages of a no-load mutual fund with Morgan Stanley
and its affiliates providing customized  services as Adviser, Administrator  and
Distributor.  Each portfolio offers Class A shares and, except the International
Small Cap, Money Market and Municipal Money Market Portfolios, also offers Class
B shares. Each portfolio has its own investment objective and policies  designed
to meet its specific goals. The investment objective of the Gold Portfolio is as
follows:
    
 
   
    - The  GOLD  PORTFOLIO  seeks long-term  capital  appreciation  by investing
      primarily in the equity securities of foreign and domestic issuers engaged
      in gold-related activities.
    
 
   
    The other portfolios of the Fund  are described in other prospectuses  which
may  be obtained from the Fund at the  address and telephone number noted on the
cover page  of  this  Prospectus.  The  investment  objectives  of  these  other
portfolios are listed below:
    
 
    GLOBAL AND INTERNATIONAL EQUITY:
 
    - The   ACTIVE   COUNTRY  ALLOCATION   PORTFOLIO  seeks   long-term  capital
      appreciation by investing in accordance with country weightings determined
      by the Adviser  in equity  securities of  non-U.S. issuers  which, in  the
      aggregate, replicate broad country indices.
 
    - The  ASIAN  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
      investing primarily in equity securities of Asian issuers.
 
   
    - The CHINA GROWTH PORTFOLIO seeks to provide long-term capital appreciation
      by investing primarily  in equity  securities of issuers  in The  People's
      Republic of China, Hong Kong and Taiwan.
    
 
    - The  EMERGING MARKETS  PORTFOLIO seeks  long-term capital  appreciation by
      investing primarily in equity securities of emerging country issuers.
 
    - The EUROPEAN  EQUITY PORTFOLIO  seeks  long-term capital  appreciation  by
      investing primarily in equity securities of European issuers.
 
    - The  GLOBAL  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation by
      investing primarily in equity securities of issuers throughout the  world,
      including U.S. issuers.
 
    - The INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of non-U.S. issuers.
 
   
    - The INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation by
      investing  primarily in equity securities of non-U.S. issuers domiciled in
      EAFE countries.
    
 
    - The INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital appreciation
      by investing  primarily  in equity  securities  of non-U.S.  issuers  with
      equity market capitalizations of less than $1 billion.
 
                                       6
<PAGE>
    - The  JAPANESE  EQUITY PORTFOLIO  seeks  long-term capital  appreciation by
      investing primarily in equity securities of Japanese issuers.
 
   
    - The LATIN  AMERICAN  PORTFOLIO  seeks long-term  capital  appreciation  by
      investing  primarily in equity  securities of Latin  American issuers and,
      from time to time, debt securities issued or guaranteed by Latin  American
      governments or governmental entities.
    
 
    U.S. EQUITY:
 
    - The  AGGRESSIVE EQUITY  PORTFOLIO seeks capital  appreciation by investing
      primarily in corporate equity and equity-linked securities.
 
   
    - The EMERGING  GROWTH PORTFOLIO  seeks  long-term capital  appreciation  by
      investing    primarily   in    growth-oriented   equity    securities   of
      small-to-medium-sized corporations.
    
 
    - The EQUITY  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation  by
      investing  in  growth-oriented  equity  securities  of  medium  and  large
      capitalization companies.
 
    - The MICROCAP PORTFOLIO seeks  long-term capital appreciation by  investing
      primarily in growth-oriented equity securities of small corporations.
 
   
    - The  SMALL CAP VALUE EQUITY PORTFOLIO seeks high long-term total return by
      investing  in  undervalued  equity  securities  of   small-to-medium-sized
      companies.
    
 
   
    - The TECHNOLOGY PORTFOLIO seeks long-term capital appreciation by investing
      primarily  in equity securities  of companies that, in  the opinion of the
      Portfolio's  investment  adviser,  are  expected  to  benefit  from  their
      involvement in technology and technology-related industries.
    
 
    - The  U.S. REAL  ESTATE PORTFOLIO  seeks to  provide above  average current
      income and long-term capital appreciation by investing primarily in equity
      securities of companies in the  U.S. real estate industry, including  real
      estate investment trusts.
 
    - The  VALUE EQUITY PORTFOLIO seeks high total return by investing in equity
      securities which the Adviser  believes to be  undervalued relative to  the
      stock market in general at the time of purchase.
 
    EQUITY AND FIXED INCOME:
 
    - The BALANCED PORTFOLIO seeks high total return while preserving capital by
      investing  in  a combination  of undervalued  equity securities  and fixed
      income securities.
 
    FIXED INCOME:
 
    - The EMERGING MARKETS DEBT PORTFOLIO  seeks high total return by  investing
      primarily   in  debt  securities  of  government,  government-related  and
      corporate issuers in emerging countries.
 
    - The FIXED INCOME PORTFOLIO seeks to produce a high total return consistent
      with the preservation of capital  by investing in a diversified  portfolio
      of fixed income securities.
 
    - The GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real rate
      of return while preserving capital by investing in fixed income securities
      of issuers throughout the world, including U.S. issuers.
 
                                       7
<PAGE>
    - The  HIGH YIELD PORTFOLIO seeks to maximize total return by investing in a
      diversified portfolio of high yield  fixed income securities that offer  a
      yield  above  that generally  available on  debt  securities in  the three
      highest rating categories of the recognized rating services.
 
    - The MORTGAGE-BACKED SECURITIES PORTFOLIO seeks to produce as high a  level
      of  current income  as is consistent  with the preservation  of capital by
      investing primarily  in  a  variety  of  investment-grade  mortgage-backed
      securities.
 
   
    - The  MUNICIPAL BOND  PORTFOLIO seeks  to produce  a high  level of current
      income consistent with preservation of principal by investing primarily in
      municipal obligations, the interest on which is exempt from federal income
      tax.
    
 
    MONEY MARKET:
 
    - The MONEY MARKET PORTFOLIO seeks  to maximize current income and  preserve
      capital  while maintaining high  levels of liquidity  through investing in
      high quality money  market instruments  with remaining  maturities of  one
      year or less.
 
    - The  MUNICIPAL MONEY MARKET PORTFOLIO seeks to maximize current tax-exempt
      income and preserve  capital while  maintaining high  levels of  liquidity
      through  investing in high quality money market instruments with remaining
      maturities of one year or less which are exempt from federal income tax.
 
   
   THE CHINA  GROWTH, MICROCAP  AND  MORTGAGE-BACKED SECURITIES  PORTFOLIOS  ARE
   CURRENTLY NOT BEING OFFERED.
    
 
INVESTMENT MANAGEMENT
 
   
    Morgan  Stanley Asset Management  Inc., a wholly  owned subsidiary of Morgan
Stanley Group  Inc.,  which,  together  with  its  affiliated  asset  management
companies,  at March  31, 1997  had in  excess of  $118 billion  in assets under
management as  an  investment  manager  or  as  a  fiduciary  adviser,  acts  as
investment  adviser to  the Fund  and each  of its  portfolios. Sun  Valley Gold
Company (the "Sub-Adviser"), which  at February 28, 1997,  had in excess of  $32
million  in assets under  management, acts as sub-adviser  to the Portfolio. See
"Management of the Fund --  Investment Adviser and Sub-Adviser" and  "Management
of the Fund -- Administrator."
    
 
HOW TO INVEST
 
   
    Class  A shares of  the Portfolio are  offered directly to  investors at net
asset value with no  sales commission or  12b-1 charges. Class  B shares of  the
Portfolio  are offered at net  asset value with no  sales commission, but with a
12b-1 fee, which  is accrued daily  and paid  quarterly, equal to  0.25% of  the
Class B shares' average daily net assets on an annualized basis. Share purchases
may  be  made  by  sending  investments directly  to  the  Fund  or  through the
Distributor. The minimum initial investment, generally, is $500,000 for Class  A
shares  of the Portfolio and  $100,000 for Class B  shares of the Portfolio. The
minimum  initial  investment  amount  is  reduced  for  certain  categories   of
investors.  For additional  information on  how to  purchase shares  and minimum
initial investments, see "Purchase of Shares."
    
 
HOW TO REDEEM
 
   
    Shares of the Portfolio may  be redeemed at any  time, without cost, at  the
net  asset value  per share  of shares of  the applicable  class next determined
after  receipt  of  the  redemption   request.  The  redemption  price  may   be
    
 
                                       8
<PAGE>
   
more  or less than the purchase price.  Certain redemptions that cause the value
of an  account  to remain  for  a continuous  60-day  period below  the  minimum
investment  amount for the  Class A shares or  for Class B  shares may result in
involuntary redemption or  automatic conversion. For  additional information  on
how  to redeem shares and involuntary redemption or conversion, see "Purchase of
Shares --  Minimum  Account Sizes  and  Involuntary Redemption  of  Shares"  and
"Redemption of Shares."
    
 
RISK FACTORS
 
   
    The   investment  policies  of  the   Portfolio  entail  certain  risks  and
considerations of which an investor should be aware. The Portfolio's investments
may be subject to greater risk and  market fluctuation than a fund that  invests
in   securities  representing  a  broader   range  of  investment  alternatives.
Historically, stock  prices of  companies  involved in  precious  metals-related
industries  have been volatile.  In addition, prices of  gold and other precious
metals and minerals  may fluctuate  sharply over short  periods of  time due  to
various  world-wide economic, financial and political factors. The Portfolio may
also invest in securities of foreign issuers which are subject to certain  risks
not  typically associated with  domestic securities. In  addition, the Portfolio
may invest in repurchase agreements, lend its portfolio securities and  purchase
securities  on a when-issued basis. The Portfolio may invest in foreign currency
forward contracts to hedge currency risk associated with investment in  non-U.S.
dollar  denominated securities. The Portfolio may invest in certain derivatives,
including options,  futures and  options on  futures. These  investments  entail
certain  costs and risks,  including imperfect correlation  between the value of
securities held by  the Portfolio  and the  value of  the particular  derivative
instrument,  and the risk that  the Portfolio could not  close out a derivatives
position when it would  be most advantageous  to do so.  The Portfolio may  also
invest  in securities  that are  neither listed on  a stock  exchange nor traded
over-the-counter,  including  private  placement   securities.  Each  of   these
investment   strategies  involves  specific  risks  which  are  described  under
"Investment Objective and Policies" and "Additional Investment Information."
    
 
                                       9
<PAGE>
                       INVESTMENT OBJECTIVE AND POLICIES
 
   
    The  investment  objective  of  the  Gold  Portfolio  is  long-term  capital
appreciation.  The  production  of  any current  income  is  incidental  to this
objective. The Portfolio seeks to  achieve its objective by investing  primarily
in the equity securities of foreign and domestic issuers engaged in gold-related
activities.  There can be no assurance that the Portfolio's investment objective
will be achieved. The Portfolio's  investment objective is a fundamental  policy
which  may not be changed without the  approval of a majority of the Portfolio's
outstanding voting securities.  In addition  to the  investments and  strategies
described  below, the Portfolio may invest in certain securities and obligations
as set  forth  in  "Additional Investment  Information"  below.  The  investment
policies described below are not fundamental policies and may be changed without
shareholder  approval. Because the securities in which the Portfolio invests may
involve risks not associated with more traditional investments, an investment in
the Portfolio,  by  itself,  should  not be  considered  a  balanced  investment
program.
    
 
   
    Under  normal circumstances, the  Portfolio will invest at  least 70% of its
total assets  in  equity securities  of  companies principally  engaged  in  the
exploration,  mining, fabrication,  processing, distribution or  trading of gold
(or, to a lesser degree, silver, platinum or other precious metals or  minerals)
or  the financing,  managing, controlling or  operating of  companies engaged in
such activities. (Such activities and the activities of such related  financing,
managing,   controlling  or  operating  companies  are  referred  to  herein  as
"gold-related" or "precious-metals-related" activities.)  For these purposes,  a
company  will be considered to  be principally engaged in  such activities if it
derives more than 50% of  its income, or devotes 50%  or more of its assets,  to
such activities. With respect to the Portfolio, equity securities include common
and  preferred  stocks,  convertible  securities,  and  rights  and  warrants to
purchase common stocks.  The Portfolio will  invest more than  25% of its  total
assets  in  securities  of companies  in  the  group of  industries  involved in
gold-related or precious-metals-related activities, as described above, and  may
invest  more than 25% of its total assets in one or more of the industries, such
as mining, that  are a part  of such  group of industries,  as described  above.
Potential  investors in the Portfolio should  consider the possibly greater risk
arising from  the  concentration of  the  Portfolio's investments  in  one  such
industry or the group of industries.
    
 
   
    Because most of the world's gold production is outside of the United States,
the  Portfolio expects that a significant portion  of its assets may be invested
in  securities  of  foreign  issuers.  The  percentage  of  assets  invested  in
particular countries or regions will change from time to time in accordance with
the  judgment of  Morgan Stanley Asset  Management Inc. (the  "Adviser") and Sun
Valley Gold Company (the "Sub-Adviser",  and collectively with the Adviser,  the
"Advisers"),  which may  be based on,  among other things,  consideration of the
political stability and economic  outlook of these countries  or regions. It  is
currently  anticipated, however, that the Portfolio's assets will be principally
invested in the  equity securities of  companies located in  the United  States,
Canada  and  Australia, and  the Portfolio's  assets may  be invested  in equity
securities of companies located in South Africa.
    
 
   
    The Portfolio expects to invest in foreign securities by buying the  foreign
securities  themselves, but the Portfolio may also invest in American Depositary
Receipts ("ADRs") and other Depositary Receipts, or similar securities that  are
convertible  into securities of  foreign issuers and  that evidence ownership of
the underlying foreign security when the Advisers believe that it is in the best
interest of the Portfolio to do so.
    
 
    The Portfolio may also invest up to 10% of its total assets in gold bullion.
Bullion will only be bought from and  sold to U.S. and foreign banks,  regulated
U.S.    commodities   exchanges,   exchanges   affiliated   with   a   regulated
 
                                       10
<PAGE>
U.S. stock  exchange, and  dealers who  are members  of, or  affiliated with,  a
regulated  U.S. commodities  exchange, in accordance  with applicable investment
laws. Investors  should  note that  bullion  offers the  potential  for  capital
appreciation  or depreciation,  but unlike  other investments  does not generate
income. In  bullion transactions,  the Portfolio  may encounter  higher  custody
costs  and other costs (including shipping  and insurance) than those costs that
are normally associated with  ownership of securities. The  Fund may attempt  to
minimize  the costs associated with the actual  custody of bullion by the use of
receipts or  certificates  representing  ownership  interests  in  bullion.  The
Advisers  currently intend to use the Portfolio's investments in gold bullion as
a short-term investment for portfolio management purposes.
 
   
    The Portfolio  may also  invest up  to 30%  of its  assets in  money  market
instruments  under normal circumstances, although  the Portfolio intends to stay
invested in securities satisfying its primary investment objective to the extent
practicable. Money market instruments include obligations of the U.S. Government
and  its  agencies  and  instrumentalities,  commercial  paper  including   bank
obligations,  certificates  of  deposit  (including  Eurodollar  certificates of
deposit) and repurchase agreements.
    
 
   
    For hedging purposes  only, the  Portfolio may enter  into foreign  currency
forward  contracts, covered  call and put  options (listed on  a U.S. securities
exchange or  written  in the  over-the-counter  market), futures  contracts  and
options  on futures.  The Portfolio may  also enter  into repurchase agreements,
purchase securities on  a when-issued  or delayed  delivery basis  and lend  its
portfolio securities.
    
 
                       ADDITIONAL INVESTMENT INFORMATION
 
   
    DEPOSITARY  RECEIPTS.   The Portfolio is  permitted to  invest indirectly in
securities of foreign companies through sponsored or unsponsored ADRs,  European
Depositary  Receipts  ("EDRs"), Global  Depositary  Receipts ("GDRs")  and other
types of Depositary  Receipts (which,  together with  ADRs, EDRs  and GDRs,  are
hereinafter  collectively referred to  as "Depositary Receipts"),  to the extent
such Depositary Receipts are  or become available.  Depositary Receipts are  not
necessarily  denominated in the  same currency as  the underlying securities. In
addition, the  issuers  of  the  securities  underlying  unsponsored  Depositary
Receipts are not obligated to disclose material information in the United States
and,  therefore, there may be less  information available regarding such issuers
and there may not be a correlation between such information and the market value
of the  Depositary Receipts.  ADRs are  securities typically  issued by  a  U.S.
financial  institution (a "depositary"), that  evidence ownership interests in a
security or  pool or  securities issued  by a  foreign issuer  (the  "underlying
issuer")  and deposited with the depositary.  GDRs and other types of Depositary
Receipts are typically issued by foreign depositaries, although they also may be
issued by U.S.  financial institutions,  and evidence ownership  interests in  a
security or pool of securities issued by either a foreign or a U.S. corporation.
Generally,  Depositary Receipts in  registered form are designed  for use in the
U.S. securities market and Depositary Receipts  in bearer form are designed  for
use  in  securities  markets outside  the  United  States. For  purposes  of the
Portfolio's investment  policies,  the  Portfolio's  investments  in  Depositary
Receipts  will be  deemed to  be investments  in the  underlying securities. The
issuers of the stock of unsponsored ADRs are not obligated to disclose  material
information  in the United States and therefore,  there may not be a correlation
between such information and the market value of the ADR. In the event that ADRs
or EDRs are not available for a particular security, the Portfolio may invest in
that security, which may or may not be listed on a foreign securities exchange.
    
 
                                       11
<PAGE>
   
    FOREIGN CURRENCY FORWARD CONTRACTS.   The Portfolio  may enter into  foreign
currency  forward contracts ("forward contracts")  that provide for the purchase
or sale of an amount of a specified currency at a future date. The Portfolio may
use such contracts to  protect against a decline  in a foreign currency  against
the  U.S. dollar between the  trade date and settlement  date when the Portfolio
purchases or sells securities,  lock in the U.S.  dollar value of dividends  and
interest  on securities held by the Portfolio, and generally to protect the U.S.
dollar  value  of  securities  held  by  the  Portfolio  against  exchange  rate
fluctuation.  While forward contracts  may limit losses as  a result of exchange
rate fluctuations, they will also limit any gains that might otherwise have been
realized. The Portfolio's  Custodian may  be required  to place  cash or  liquid
securities  in  a segregated  account in  an amount  equal to  the value  of the
Portfolio's total assets committed to the consummation of forward contracts.  If
the  value  of  the  securities  placed  in  the  segregated  account  declines,
additional cash or securities will be placed in the account on a daily basis  so
that  the value  of the  account will  be at  least equal  to the  amount of the
Portfolio's commitments with respect to such contracts.
    
 
   
    FOREIGN INVESTMENT.   Investment in securities  of foreign issuers  involves
somewhat different investment risks than those affecting U.S. investments. There
may  be limited publicly available information  with respect to foreign issuers,
and foreign issuers are  not generally subject  to uniform accounting,  auditing
and  financial  standards and  requirements  comparable to  those  applicable to
domestic companies. There may also be less government supervision and regulation
of foreign securities exchanges, brokers and listed companies than in the United
States. Many foreign securities markets have substantially less volume than U.S.
national securities exchanges, and securities  of some foreign issuers are  less
liquid  and  more  volatile  than  securities  of  comparable  domestic issuers.
Brokerage  commissions  and  other  transaction  costs  on  foreign   securities
exchanges are generally higher than in the United States. Dividends and interest
paid  by foreign issuers may be subject  to withholding and other foreign taxes,
which may  decrease  the  net  return on  foreign  investments  as  compared  to
dividends  and interest paid to  the Portfolio by domestic  companies. It is not
expected that the Portfolio or its shareholders would be able to claim a  credit
for  U.S. tax purposes with respect to  any such foreign taxes. Additional risks
include future  political  and economic  developments,  the possibility  that  a
foreign  jurisdiction might impose or change withholding taxes on income payable
with  respect  to  foreign  securities,  possible  seizure,  nationalization  or
expropriation  of  the  foreign  issuer or  foreign  deposits  and  the possible
adoption of foreign governmental restrictions such as exchange controls. Current
developments in South Africa have raised the threat of political instability and
uncertainty concerning the impact of such instability on South Africa's  economy
and  businesses. Accordingly, the risk of  investing in securities of issuers in
South Africa may be greater  than the risk of  investing in more stable  foreign
countries.
    
 
   
    Investments  in securities of foreign  issuers are frequently denominated in
foreign currencies, and the Portfolio  may temporarily hold uninvested  reserves
in  bank deposits in foreign currencies, the  value of the Portfolio's assets as
measured in U.S. dollars may be affected favorably or unfavorably by changes  in
currency  rates and  exchange control regulations,  and the  Portfolio may incur
costs in connection with conversions between various currencies.
    
 
   
    FUTURES CONTRACTS  AND OPTIONS  ON  FUTURES CONTRACTS.   The  Portfolio  may
purchase  and sell futures contracts and options on futures contracts, including
but not limited to financial futures, securities index futures, foreign currency
exchange futures, and interest rate futures contracts. Futures contracts provide
for the sale by one party and purchase by another party of a specified amount of
a specific security, instrument or basket
    
 
                                       12
<PAGE>
   
thereof, at a  specific future date  and at a  specified price. An  option on  a
futures  contract is a legal contract that gives  the holder the right to buy or
sell a specified amount  of futures contracts at  a fixed or determinable  price
upon the exercise of the option.
    
 
   
    The  Portfolio may  sell securities  index futures  contracts and/or options
thereon in anticipation of or during a  market decline to attempt to offset  the
decrease in market value of investments in its portfolio, or purchase securities
index  futures in order to gain market exposure. Subject to applicable laws, the
Portfolio may engage in transactions in securities index futures contracts  (and
options  thereon)  which  are  traded  on  a  recognized  securities  or futures
exchange, or  may purchase  or  sell such  instruments in  the  over-the-counter
market. There currently are limited securities index futures and options on such
futures  in many countries,  particularly emerging countries.  The nature of the
strategies adopted by the Adviser, and the extent to which those strategies  are
used, may depend on the development of such markets.
    
 
   
    The Portfolio may engage in transactions involving foreign currency exchange
futures  contracts. Such contracts  involve an obligation to  purchase or sell a
specific currency  at a  specified future  date and  at a  specified price.  The
Portfolio may engage in such transactions to hedge their respective holdings and
commitments  against changes in  the level of  future currency rates  or to gain
exposure to a particular currency.
    
 
   
    The  Portfolio  may  engage  in   transactions  in  interest  rate   futures
transactions.  Interest rate futures contracts involve an obligation to purchase
or sell a specific  debt security, instrument or  basket thereof at a  specified
future  date at  a specified price.  The value  of the contract  rises and falls
inversely with  changes in  interest rates.  The Portfolio  may engage  in  such
transactions  to hedge their holdings of debt instruments against future changes
in interest rates.
    
 
   
    Financial futures are futures  contracts relating to financial  instruments,
such  as  U.S. Government  securities, foreign  currencies, and  certificates of
deposit. Such contracts  involve an obligation  to purchase or  sell a  specific
security, instrument or basket thereof at a specified future date at a specified
price.  Like interest  rate futures  contracts, the  value of  financial futures
contracts rises  and  falls  inversely  with  changes  in  interest  rates.  The
Portfolio  may engage in financial futures contracts for hedging and non-hedging
purposes.
    
 
   
    Under rules  adopted  by  the  Commodity  Futures  Trading  Commission,  the
Portfolio  may enter into futures contracts and options thereon for both hedging
and non-hedging purposes,  provided that  not more  than 5%  of the  Portfolio's
total  assets at the time of entering the transaction are required as margin and
option  premiums  to  secure  obligations  under  such  contracts  relating   to
activities  that do not  constitute "bona fide" hedging.  The Portfolio will not
enter into futures contracts to the  extent that its outstanding obligations  to
purchase  securities under such  contracts, in combination  with its outstanding
obligations with respect to options transactions (including options to  purchase
securities or instruments) would exceed 20% of its total assets.
    
 
   
    Gains  and losses  on futures  contracts and  options thereon  depend on the
Adviser's ability  to  predict correctly  the  direction of  securities  prices,
interest  rates and other economic factors.  Other risks associated with the use
of futures  and options  are (i)  imperfect correlation  between the  change  in
market  value of investments held by the Portfolio and the prices of futures and
options relating to  investments purchased or  sold by the  Portfolio, and  (ii)
possible  lack  of a  liquid secondary  market  for a  futures contract  and the
resulting inability to  close a futures  position. The risk  that the  Portfolio
will  be unable  to close  out a  futures position  or options  contract will be
minimized by only entering  into futures contracts  or options transactions  for
which there
    
 
                                       13
<PAGE>
   
appears to be a liquid exchange or secondary market. The risk of loss in trading
on  futures contracts in some strategies can be substantial, due both to the low
margin deposits required and the extremely  high degree of leverage involved  in
futures pricing.
    
 
   
    GOLD  RELATED INVESTMENTS.  The Portfolio intends  to invest at least 70% of
its total assets in securities of companies engaged in gold-related  activities.
As  a result of this policy, which is a fundamental policy of the Portfolio, the
Portfolio's investments may be  subject to greater  risk and market  fluctuation
than  a  fund  that  invests  in  securities  representing  a  broader  range of
investment alternatives.  Historically, stock  prices of  companies involved  in
precious-metals-related  industries  have been  volatile. Investment  related to
gold and other precious metals and  minerals are considered speculative and  are
impacted  by a variety of world-wide  economic, financial and political factors.
Prices of  gold and  other  precious metals  may  fluctuate sharply  over  short
periods  of time due to changes in inflation or expectations regarding inflation
in various countries, the availability  of supplies of precious metals,  changes
in  industrial and commercial demand, metal  sales by governments, central banks
or international agencies, investment  speculation, monetary and other  economic
policies of various governments and government restrictions on private ownership
of certain precious metals and minerals.
    
 
   
    LOANS  OF  PORTFOLIO  SECURITIES.   The  Portfolio  may  lend  securities to
brokers, dealers, domestic and foreign banks or other financial institutions for
the purpose of increasing its net investment income. These loans must be secured
continuously by cash or equivalent collateral, or by a letter of credit at least
equal to the  market value  of the securities  loaned plus  accrued interest  or
income.  There may be a risk of delay in recovery of the securities or even loss
of rights  in  the  collateral  should  the  borrower  of  the  securities  fail
financially.  The  Portfolio will  not enter  into securities  loan transactions
exceeding, in the aggregate, 33 1/3% of the market value of its total assets.
    
 
   
    MONEY MARKET INSTRUMENTS.   The Portfolio  is permitted to  invest in  money
market   instruments,  although  the  Portfolio  intends  to  stay  invested  in
securities satisfying its primary investment objective to the extent  practical.
The  Portfolio may  make money market  investments pending  other investments or
settlement for  liquidity,  or  in adverse  market  conditions.  See  "Temporary
Investments."  The money market investments  permitted for the Portfolio include
obligations of  the  U.S. Government  and  its agencies  and  instrumentalities;
obligations  of foreign sovereignties; other  debt securities; commercial paper;
bank obligations; certificates of deposit (including Eurodollar certificates  of
deposit); and repurchase agreements.
    
 
   
    NON-PUBLICLY   TRADED   SECURITIES,   PRIVATE   PLACEMENTS   AND  RESTRICTED
SECURITIES.  The Portfolio may invest in securities that are neither listed on a
stock  exchange  nor   traded  over-the-counter,   including  privately   placed
securities.  Such  unlisted equity  securities may  involve  a higher  degree of
business and financial risk that can  result in substantial losses. As a  result
of the absence of a public trading market for these securities, they may be less
liquid  than publicly traded securities. Although these securities may be resold
in privately negotiated transactions, the prices realized from these sales could
be less than those  originally paid by  the Portfolio or less  than what may  be
considered   the  fair  value  of  such  securities.  Further,  companies  whose
securities are not  publicly traded  may not be  subject to  the disclosure  and
other  investor  protection  requirements  which might  be  applicable  if their
securities  were  publicly  traded.  If  such  securities  are  required  to  be
registered  under the securities laws of  one or more jurisdictions before being
resold, the Portfolio may be required to bear the expenses of registration.
    
 
                                       14
<PAGE>
   
    As a general matter, the Portfolio may  not invest more than 15% of its  net
assets  in  illiquid  securities, including  securities  for which  there  is no
readily available secondary market. Nor as  a general matter, may the  Portfolio
invest  more than 10% of its total assets in securities that are restricted from
sale to  the public  without registration  ("Restricted Securities")  under  the
Securities Act of 1933, as amended (the "1933 Act"). However, each Portfolio may
invest up to 20% of its total assets in liquid Restricted Securities that can be
offered  and sold  to qualified institutional  buyers under Rule  144A under the
1933 Act ("Rule 144A Securities"). The Board of Directors has adopted guidelines
and delegated  to  the Adviser,  subject  to the  supervision  of the  Board  of
Directors,  the daily  function of determining  and monitoring  the liquidity of
Rule 144A  Securities. Rule  144A Securities  may become  illiquid if  qualified
institutional buyers are not interested in acquiring the securities.
    
 
   
    OPTIONS  TRANSACTIONS.  The Portfolio may seek to increase its return or may
hedge its portfolio  investments through  options transactions  with respect  to
securities,  instruments, indices or baskets thereof  in which the Portfolio may
invest, as well  as with respect  to foreign currency.  Purchasing a put  option
gives  the Portfolio the right to sell  a specified security, currency or basket
of securities or currencies  at the exercise price  until the expiration of  the
option.  Purchasing a call  option gives the  Portfolio the right  to purchase a
specified security,  currency  or basket  of  securities or  currencies  at  the
exercise  price  until  the expiration  of  the  option. The  Portfolio  may not
purchase call and  put options to  the extent  that the value  of its  aggregate
investment in options exceeds 5% of its total assets.
    
 
   
    The  Portfolio  also  may  write  (i.e.,  sell)  put  and  call  options  on
investments held in its portfolio, as well as with respect to foreign  currency.
A  Portfolio that has written an option  receives a premium, which increases the
Portfolio's return on  the underlying security  or instrument in  the event  the
option  expires unexercised or is closed out  at a profit. However, by writing a
call option, the Portfolio will limit its opportunity to profit from an increase
in the market value of the underlying security or instrument above the  exercise
price  of the option for as long as  the Portfolio's obligation as writer of the
option continues. The  Portfolio may only  write options that  are "covered."  A
covered  call option  means that so  long as  the Portfolio is  obligated as the
writer of the  option, it  will own (i)  the underlying  security or  instrument
subject  to  the  option  or  (ii)  securities  or  instruments  convertible  or
exchangeable without  the payment  of  any consideration  into the  security  or
instrument subject to the option.
    
 
   
    By  writing (or selling) a put option, the Portfolio incurs an obligation to
buy the security or instrument underlying  the option from the purchaser of  the
put  at the option's exercise price at any time during the option period, at the
purchaser's election. Options written by the Portfolio may be exercisable by the
purchaser only on a  specific date. A  Portfolio that has  written a put  option
will  earmark or  segregate sufficient  liquid assets  to cover  its obligations
under the option.
    
 
   
    The Portfolio may  engage in  transactions in  options which  are traded  on
recognized  exchanges or  over-the-counter. There currently  are limited options
markets in  many  countries,  particularly  emerging  countries  such  as  Latin
American  countries, and the nature of the strategies adopted by the Adviser and
the extent to which those strategies are used will depend on the development  of
such  option markets. The primary  risks associated with the  use of options are
(i) imperfect  correlation between  the change  in market  value of  investments
held,  purchased or sold by the Portfolio  and the prices of options relating to
such investments; and  (ii) possible lack  of a liquid  secondary market for  an
option.
    
 
    PRECIOUS METALS FORWARD AND FUTURES CONTRACTS.  The Portfolio may enter into
futures contracts on precious metals as a hedge against changes in the prices of
precious metals held or intended to be acquired by
 
                                       15
<PAGE>
   
the   Portfolio,  but  not  for  speculation  or  for  achieving  leverage.  The
Portfolio's hedging activities may include purchases of futures contracts as  an
offset  against the effect of  anticipated increases in the  price of a precious
metal which the Portfolio intends to acquire or sales of futures contracts as an
offset against the effect of anticipated declines in the price of precious metal
which the Portfolio owns. The Portfolio  may enter into precious metals  forward
contracts,  which are similar to precious  metals futures contracts in that they
both provide for the purchase or sale of precious metals at an agreed price with
delivery to  take  place at  an  agreed  future time.  However,  unlike  futures
contracts,  forward contracts are negotiated  contracts which are primarily used
in the dealer  market. The  Portfolio will use  forward contracts  for the  same
hedging  purposes as those applicable to  futures contracts, as described above.
Precious metals futures  and forward  contract prices  can be  volatile and  are
influenced  principally  by changes  in spot  market prices,  which in  turn are
affected by a variety of political  and economic factors. While the  correlation
between  changes in prices  of futures and  forward contracts and  prices of the
precious metals  being  hedged by  such  contracts has  historically  been  very
strong,  the correlation may  be imperfect at  times, and even  a well conceived
hedge may  be  unsuccessful  to  some  degree  because  of  market  behavior  or
unexpected precious metals price trends.
    
 
    The  Portfolio may also  purchase and write  covered call or  put options on
precious metals futures contracts.  Such options would  be purchased solely  for
hedging  purposes. Call options might be  purchased to hedge against an increase
in the  price of  precious metals  the  Portfolio intends  to acquire,  and  put
options  may be purchased  to hedge against  a decline in  the price of precious
metals owned by the Portfolio. As is the case with futures contracts, options on
precious metals futures may facilitate  the Portfolio's acquisition of  precious
metals  or permit the Portfolio to defer  disposition of precious metals for tax
or other purposes.
 
   
    REPURCHASE AGREEMENTS.  The Portfolio  may enter into repurchase  agreements
with  brokers, dealers or  banks that meet  the credit guidelines  of the Fund's
Directors. In  a repurchase  agreement, the  Portfolio buys  a security  from  a
seller  that has  agreed to  repurchase it  at a  mutually agreed  upon date and
price, reflecting the interest rate effective for the term of the agreement. The
term of these agreements is usually from overnight to one week and never exceeds
one year. Repurchase agreements may be viewed as a fully collateralized loan  of
money  by the Portfolio to the  seller. The Portfolio always receives securities
with a market  value at  least equal to  the purchase  price (including  accrued
interest)  as collateral, and  this value is  maintained during the  term of the
agreement. If  the  seller  defaults  and the  collateral  value  declines,  the
Portfolio  might  incur a  loss. If  bankruptcy  proceedings are  commenced with
respect to the seller,  the Portfolio's realization upon  the collateral may  be
delayed  or limited. The Portfolio may not enter into repurchase agreements with
more than seven days to  maturity if, as a result,  more than 15% of the  market
value  of the Portfolio's net assets are  invested in these agreements and other
investments for which market quotations are  not readily available or which  are
otherwise illiquid.
    
 
   
    TEMPORARY  INVESTMENTS.  For temporary defensive purposes, when the Advisers
determine that market conditions warrant, the Portfolio may invest up to 100% of
its assets in  dollar and  non-dollar denominated money  market instruments  and
short-  and medium-term debt securities that the  Advisers believe to be of high
quality, or hold cash. The short-  and medium-term debt securities in which  the
Portfolio  may invest consist of (a) obligations  of the U.S. or foreign country
governments, their respective agencies  or instrumentalities; (b) bank  deposits
and  bank  obligations (including  certificates  of deposit,  time  deposits and
bankers' acceptances)  of  U.S. or  foreign  country banks  denominated  in  any
currency;  (c) floating rate securities and other instruments denominated in any
currency issued by international development  agencies; (d) finance company  and
corporate
    
 
                                       16
<PAGE>
   
commercial  paper and  other short-term corporate  debt obligations  of U.S. and
foreign country corporations meeting  the Portfolio's credit quality  standards;
and (e) repurchase agreements with banks and broker-dealers with respect to such
securities.
    
 
   
    WHEN-ISSUED  AND DELAYED  DELIVERY SECURITIES.   The  Portfolio may purchase
securities on a  when-issued or  delayed delivery basis.  In such  transactions,
instruments  are bought with payment and delivery  taking place in the future in
order to secure what is considered to  be an advantageous yield or price at  the
time  of the transaction. Delivery of and  payment for these securities may take
as long as a month  or more after the date  of the purchase commitment but  will
take  place  no more  than 120  days after  the trade  date. The  Portfolio will
maintain with the Custodian  a separate account with  a segregated portfolio  of
cash  or liquid securities in an amount at least equal to these commitments. The
payment obligation and the interest rates  that will be received are each  fixed
at  the time the Portfolio enters into the commitment and no interest accrues to
the Portfolio until settlement.  Thus, it is possible  that the market value  at
the  time of  settlement could be  higher or  lower than the  purchase price if,
among other factors, the general  level of interest rates  has changed. It is  a
current  policy  of  the Portfolio  not  to enter  into  when-issued commitments
exceeding in the  aggregate 15%  of the market  value of  the Portfolio's  total
assets   less  liabilities,  other   than  the  obligations   created  by  these
commitments.
    
 
                             INVESTMENT LIMITATIONS
 
    As a diversified investment  company, the Gold Portfolio  is subject to  the
following  limitations: (a) as to 75% of its total assets, the Portfolio may not
invest more than 5%  of its total  assets in the securities  of any one  issuer,
except   obligations   of   the   U.S.   Government   and   its   agencies   and
instrumentalities, and  (b) the  Portfolio may  not  own more  than 10%  of  the
outstanding voting securities of any one issuer.
 
   
    The  Portfolio also operates under  certain investment restrictions that are
deemed fundamental limitations and may be changed only with the approval of  the
holders  of a majority  of the Portfolio's outstanding  shares and under certain
non-fundamental investment limitation  that may be  changed without  shareholder
approval.   For  additional  information   on  fundamental  and  non-fundamental
investment  limitations,  see  "Investment  Limitations"  in  the  Statement  of
Additional Information.
    
 
                             MANAGEMENT OF THE FUND
 
   
    INVESTMENT ADVISER AND SUB-ADVISER.  Morgan Stanley Asset Management Inc. is
the  Adviser  and  Administrator of  the  Fund  and the  Portfolio.  The Adviser
provides investment advice  and portfolio  management services,  pursuant to  an
Investment  Advisory Agreement  and, subject  to the  supervision of  the Fund's
Board  of  Directors,  makes  each  of  the  Portfolio's  day-to-day  investment
decisions,  arranges for the  execution of portfolio  transactions and generally
manages each of the Portfolio's investments. With respect to the Portfolio,  the
Adviser has delegated these responsibilities, subject to its supervision, to the
Sub-Adviser.  The Adviser  is entitled to  receive from the  Portfolio an annual
investment advisory fee, payable quarterly, in  an amount equal to 1.00% of  the
average daily net assets of the Portfolio.
    
 
    Sun  Valley  Gold Company  is sub-adviser  of the  Portfolio. Pursuant  to a
Sub-Advisory Agreement,  and subject  at all  times to  the supervision  of  the
Adviser  and  the  Board of  Directors  of  the Fund,  the  Sub-Adviser provides
investment advice  and  portfolio  management services,  makes  the  Portfolio's
day-to-day investment
 
                                       17
<PAGE>
decisions,  arranges for the  execution of portfolio  transactions and generally
manages the Portfolio's investments. The Sub-Adviser is entitled to receive from
the Adviser an annual sub-advisory fee, payable quarterly, in an amount equal to
0.40% of the average daily net assets of the Portfolio.
 
    The Adviser has  agreed to  a reduction  in the fees  payable to  it and  to
reimburse the Portfolio, if necessary, if such fees would cause the total annual
operating  expenses for Class  A and Class  B shares to  exceed 1.25% and 1.50%,
respectively, of its average daily net  assets. The Sub-Adviser has agreed to  a
proportionate  reduction in its fees from the Adviser if the Adviser is required
to waive its fees or  to reimburse the Portfolio  so that the Portfolio's  total
operating expenses for Class A and Class B shares do not exceed 1.25% and 1.50%,
respectively, of its average daily net assets.
 
   
    The  Adviser, with  principal offices  at 1221  Avenue of  the Americas, New
York, New York 10020,  conducts a worldwide  portfolio management business,  and
provides  a broad  range of  portfolio management  services to  customers in the
United States and  abroad. On February  5, 1997, Morgan  Stanley Group Inc.  and
Dean  Witter, Discover & Co.  announced that they had  entered into an Agreement
and Plan of Merger to  form Morgan Stanley, Dean  Witter, Discover & Co.  Morgan
Stanley  Group Inc.  is the  direct parent  of the  Adviser and  Morgan Stanley.
Subject to certain conditions  being met, it is  currently anticipated that  the
transaction  will close in mid-1997. Thereafter,  the Adviser and Morgan Stanley
will be subsidiaries of Morgan Stanley, Dean Witter, Discover & Co. At March 31,
1997 the  Adviser,  together with  its  affiliated asset  management  companies,
managed  investments totaling in excess of $118 billion, including approximately
$100 billion  under active  management and  $18 billion  as Named  Fiduciary  or
Fiduciary  Adviser. See "Management of the  Fund" in the Statement of Additional
Information.
    
 
   
    The Sub-Adviser, with principal offices at 620 Sun Valley Road, Sun  Valley,
Idaho  83340,  specializes in  the  management of  gold-related  investments. At
February 28, 1997, the Sub-Adviser managed investments totaling in excess of $32
million.
    
 
    PORTFOLIO MANAGER.  Peter F. Palmedo, the President of the Sub-Adviser since
its  inception  in   January,  1992,  has   had  primary  portfolio   management
responsibility  for the  Portfolio since  its inception.  He has  also served as
President of Sun Valley  Gold Trading, Inc.,  a registered broker-dealer,  since
its  inception in  January, 1992, and  of Mad River  Management since September,
1989. Prior thereto, Mr. Palmedo worked  at Morgan Stanley in the  institutional
equity  department and specialized in portfolio risk management, derivatives and
the development  and  analysis  of long-dated  options,  synthetic  options  and
options  embedded in securities. He  received a BA in  Business and Finance from
Hampshire College in 1979.
 
   
    ADMINISTRATOR.  The  Adviser also  provides administrative  services to  the
Fund  pursuant to an  Administration Agreement. The  services provided under the
Administration Agreement are subject to the supervision of the Officers and  the
Board  of Directors of the Fund and include day-to-day administration of matters
related to the  corporate existence  of the  Fund, maintenance  of its  records,
preparation   of  report,  supervision  of  the  Fund's  arrangements  with  its
custodian,  and  assistance  in  the  preparation  of  the  Fund's  registration
statements  under federal laws. The  Administration Agreement also provides that
the Administrator,  through its  agents, will  provide dividend  disbursing  and
transfer  agent services to the Fund.  For its services under the Administration
Agreement, the Fund  pays the Adviser  a monthly  fee which on  an annual  basis
equals 0.15% of the average daily net assets of the Portfolio.
    
 
                                       18
<PAGE>
   
    Under  an  agreement  between  the  Adviser  and  The  Chase  Manhattan Bank
("Chase"), Chase provides  certain administrative services  to the Fund  through
its  corporate  affiliate, Chase  Global Funds  Services Company  ("CGFSC"). The
Adviser supervises and monitors such administrative services provided by  CGFSC.
Their  services are also subject to the supervision of the Board of Directors of
the Fund. CGFSC's business address  is 73 Tremont Street, Boston,  Massachusetts
02108-3913.
    
 
   
    DIRECTORS  AND OFFICERS.  Pursuant to  the Fund's Articles of Incorporation,
the Board of Directors  decides upon matters of  general policy and reviews  the
actions  of  the Fund's  Adviser, Administrator,  Distributor and  other service
providers. The Officers  of the Fund  conduct and supervise  its daily  business
operations.
    
 
    DISTRIBUTOR.   Morgan  Stanley serves  as the  exclusive Distributor  of the
shares of  the Fund.  Under its  Distribution Agreement  with the  Fund,  Morgan
Stanley sells shares of the Portfolio upon the terms and at the current offering
price  described in this Prospectus. Morgan Stanley is not obligated to sell any
certain number of shares of the Portfolio.
 
    The Portfolio currently offers  only the classes of  shares offered by  this
Prospectus.  The Portfolio may in the future offer one or more classes of shares
with features, distribution expenses or  other expenses that are different  from
those of the classes currently offered.
 
   
    The  Fund has  adopted a Plan  of Distribution  with respect to  the Class B
shares of the Portfolio pursuant to Rule 12b-1 under the 1940 Act (the  "Plan").
Under  the Plan,  the Distributor  is entitled to  receive from  the Portfolio a
distribution fee, which  is accrued daily  and paid quarterly,  of 0.25% of  the
Class B shares' average daily net assets on an annualized basis. The Distributor
expects  to reallocate  most of its  fee to its  investment representatives. The
Distributor may, in its discretion, voluntarily  waive from time to time all  or
any  portion of its distribution fee and each of the Distributor and the Adviser
is free to make additional payments out of its own assets to promote the sale of
Fund shares,  including  payments  that compensate  financial  institutions  for
distribution services or shareholder services.
    
 
    The  plan is designed to compensate the Distributor for its services, not to
reimburse the Distributor for its expenses,  and the Distributor may retain  any
portion  of the fee that it does not expend in fulfillment of its obligations to
the Fund.
 
   
    EXPENSES.  The Portfolio  is responsible for payment  of certain other  fees
and  expenses  (including legal  fees,  accountant's fees,  custodial  fees, and
printing and mailing  costs) specified  in the  Administration and  Distribution
Agreements.
    
 
                               PURCHASE OF SHARES
 
    Class  A and Class B shares of the Portfolio may be purchased, without sales
commission, at the net  asset value per share  next determined after receipt  of
the purchase order by the Portfolio. See "Valuation of Shares."
 
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
 
   
    For  a  Portfolio  account  opened  on or  after  January  2,  1996  (a "New
Account"), the minimum initial investment and minimum account size are  $500,000
for  Class A shares and  $100,000 for Class B  shares. Certain advisory or asset
allocation accounts, such as Total Funds Management accounts, managed by  Morgan
Stanley  or its affiliates, including  the Adviser ("Managed Accounts") purchase
Class A shares without being subject to any
    
 
                                       19
<PAGE>
   
minimum initial investment or minimum account size requirements for a  Portfolio
account.  Employees of  the Adviser and  certain of its  affiliates may purchase
Class A  shares  subject  to  conditions,  including  a  lower  minimum  initial
investment, established by Officers of the Fund.
    
 
    If the value of a New Account containing Class A shares falls below $500,000
(but  remains at  or above $100,000)  because of  shareholder redemption(s), the
Fund will  notify  the shareholder,  and  if  the account  value  remains  below
$500,000  (but remains at or above $100,000) for a continuous 60-day period, the
Class A  shares in  such account  will convert  to Class  B shares  and will  be
subject  to the distribution  fee and other  features applicable to  the Class B
shares. The Fund, however,  will not convert  Class A shares  to Class B  shares
based  solely upon  changes in  the market  that reduce  the net  asset value of
shares. Under  current tax  law, conversions  between share  classes are  not  a
taxable event to the shareholder.
 
    Shares  in a Portfolio account opened prior  to January 2, 1996 (a "Pre-1996
Account") were  designated  Class A  shares  on January  2,  1996. Shares  in  a
Pre-1996  Account  with  a  value  of  $100,000 or  more  on  March  1,  1996 (a
"Grandfathered Class A Account") remained  Class A shares regardless of  account
size  thereafter. Except for shares  in a Managed Account,  shares in a Pre-1996
Account with a value of  less than $100,000 on  March 1, 1996 (a  "Grandfathered
Class  B Account") converted to  Class B shares on  March 1, 1996. Grandfathered
Class A Accounts and Managed Accounts are not subject to conversion from Class A
shares to Class B shares.
 
    Investors may also invest in the  Fund by purchasing shares through a  trust
department, broker, dealer, agent, financial planner, financial services firm or
investment  adviser.  An  investor  may  be  charged  an  additional  service or
transaction fee by that institution.
 
   
    The minimum investment levels may be waived at the discretion of the Adviser
for (i) certain employees and customers of Morgan Stanley or its affiliates  and
certain   trust  departments,  brokers,  dealers,  agents,  financial  planners,
financial services  firms, or  investment  advisers that  have entered  into  an
agreement  with  Morgan  Stanley  or its  affiliates;  and  (ii)  retirement and
deferred compensation plans and trusts used  to fund such plans, including,  but
not  limited to, those defined in Section  401(a), 403(b) or 457 of the Internal
Revenue Code  of 1986,  as amended  (the "Code")  and "rabbi  trusts". The  Fund
reserves  the right to modify or terminate the conversion features of the shares
as stated above at any time upon 60-days notice to shareholders.
    
 
   
    The Adviser reserves the right in its sole discretion to determine which  of
such  advisory  or  asset allocation  accounts  shall be  Managed  Accounts. For
information regarding  Managed  Accounts,  please contact  your  Morgan  Stanley
account representative or the Fund at the telephone number provided on the cover
of this Prospectus.
    
 
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
 
    If  the value of a  New Account falls below  $100,000 because of shareholder
redemption(s), the Fund will  notify the shareholder, and  if the account  value
remains  below  $100,000 for  a  continuous 60-day  period,  the shares  in such
account are subject to redemption  by the Fund and,  if redeemed, the net  asset
value  of  such shares  will  be promptly  paid  to the  shareholder.  The Fund,
however, will not  redeem shares based  solely upon changes  in the market  that
reduce the net asset value of shares.
 
   
    Grandfathered  Class A Accounts, Grandfathered  Class B Accounts and Managed
Accounts are not subject to involuntary redemption. The Fund reserves the  right
to  modify or  terminate the  involuntary redemption  features of  the shares as
stated above at any time upon 60-days notice to shareholders.
    
 
                                       20
<PAGE>
CONVERSION FROM CLASS B TO CLASS A SHARES
 
   
    If the value of Class B shares in a Portfolio account increases, whether due
to shareholder share  purchases or  market activity,  to $500,000  or more,  the
Class  B shares  will convert  to Class  A shares.  Under current  tax law, such
conversion is not a taxable event  to the shareholder. Class A shares  converted
from  Class B shares are  subject to the same  minimum account size requirements
that are applicable to New Accounts containing Class A shares, as stated  above.
The  Fund reserves the right  to modify or terminate  this conversion feature at
any time upon 60-days notice to shareholders.
    
 
INITIAL PURCHASES DIRECTLY FROM THE FUND
 
    The Fund's determination of an investor's eligibility to purchase shares  of
a  given class will  take precedence over  the investor's selection  of a class.
Assuming the investor is eligible for the  class, the Fund will select the  most
favorable class for the investor, if the investor has not done so.
 
   
1) BY  CHECK.   An account may  be opened  by completing and  signing an Account
   Registration Form, and mailing  it, together with  a check ($500,000  minimum
   for  Class A shares of the Portfolio  and $100,000 minimum for Class B shares
   of the Portfolio, with  certain exceptions for  Morgan Stanley employees  and
   select  customers)  payable to  "Morgan Stanley  Institutional Fund,  Inc. --
   [portfolio name]", to:
    
 
       Morgan Stanley Institutional Fund, Inc.
        P.O. Box 2798
        Boston, Massachusetts 02208-2798
 
   
Payment will be accepted only in U.S. dollars, unless prior approval for payment
by other  currencies is  given  by the  Fund. The  class(es)  of shares  of  the
Portfolio to be purchased should be designated on the Account Registration Form.
For  purchases  by check,  the Fund  is ordinarily  credited with  Federal Funds
within one business day.  Thus, your purchase of  shares by check is  ordinarily
credited  to your  account at  the net  asset value  per share  of the Portfolio
determined on the next business day after receipt.
    
 
2) BY FEDERAL  FUNDS WIRE.   Purchases  may be  made by  having your  bank  wire
   Federal  Funds to the Fund's bank account.  In order to ensure prompt receipt
   of your Federal Funds Wire, it is important that you follow these steps:
 
   
A.  Telephone  the Fund  (toll free: 1-800-548-7786)  and provide  us with  your
    name,  address,  telephone  number, Social  Security  or  Tax Identification
    Number, the  portfolio(s) selected,  the class  selected, the  amount  being
    wired,  and by  which bank.  We will  then provide  you with  a Fund account
    number. (Investors with existing accounts should also notify the Fund  prior
    to wiring funds.)
    
 
                                       21
<PAGE>
B.    Instruct  your  bank to  wire  the  specified amount  to  the  Fund's Wire
    Concentration Bank Account (be  sure to have your  bank include the name  of
    the  portfolio(s)  selected,  the  class  selected  and  the  account number
    assigned to you) as follows:
 
   
      The Chase Manhattan Bank
       One Manhattan Plaza
       New York, NY 10081-1000
       ABA #021000021
       DDA #910-2-733293
       Attn: Morgan Stanley Institutional Fund, Inc.
       Ref: (Portfolio name, your account number, your account name)
    
 
       Please call the Fund at 1-800-548-7786 prior to wiring funds.
 
C.  Complete and sign the Account  Registration Form and mail it to the  address
    shown thereon.
 
   
  The  purchase price of the Class A and  Class B shares of the Portfolio is the
  net asset value next determined after the order is received. See "Valuation of
  Shares." An order received prior  to the regular close  of the New York  Stock
  Exchange  ("NYSE"),  which  is currently  4:00  p.m. (Eastern  Time),  will be
  executed at the price computed on the date of receipt; an order received after
  the regular close of the  NYSE will be executed at  the price computed on  the
  next  day the NYSE is  open as long as the  Transfer Agent receives payment by
  check or in Federal Funds prior to the regular close of the NYSE on such day.
    
 
  Federal Funds purchase orders will be accepted only on a day on which the Fund
  and Chase (the "Custodian Bank") are open for business. Your bank may charge a
  service fee for wiring funds.
 
3) BY BANK WIRE.   The  same procedure outlined  under "By  Federal Funds  Wire"
   above  must be  followed in  purchasing shares  by bank  wire. However, money
   transferred by bank wire may or may  not be converted into Federal Funds  the
   same  day, depending on the time the  money is received and the bank handling
   the wire. Prior to such conversion, an investor's money will not be invested.
   Your bank may charge a service fee for wiring funds.
 
ADDITIONAL INVESTMENTS
 
   
    You may  add to  your account  at any  time (minimum  additional  investment
$1,000,  except  for  automatic  reinvestment  of  dividends  and  capital gains
distributions for which there are no minimums) by purchasing shares at net asset
value by mailing a check to  the Fund (payable to "Morgan Stanley  Institutional
Fund, Inc. -- [portfolio name]") at the above address or by wiring monies to the
Custodian  Bank as outlined above. It is  very important that your account name,
the portfolio name and the class selected be specified in the letter or wire  to
ensure  proper crediting  to your  account. In  order to  ensure that  your wire
orders are invested  promptly, you  are requested to  notify one  of the  Fund's
representatives  (toll free: 1-800-548-7786) prior  to the wire date. Additional
investments will be applied to purchase additional shares in the same class held
by a shareholder in a Portfolio account.
    
 
OTHER PURCHASE INFORMATION
 
   
    Although the legal rights of Class A  and Class B shares will be  identical,
the  different expenses borne by  each class will result  in different net asset
values  and  dividends.   The  net   asset  value   of  Class   B  shares   will
    
 
                                       22
<PAGE>
generally be lower than the net asset value of Class A shares as a result of the
distribution  expense charged to  Class B shares. It  is expected, however, that
the net  asset  value  per share  of  the  two classes  will  tend  to  converge
immediately  after the recording of dividends which will differ by approximately
the amount of the distribution expense accrual differential between the classes.
 
    In the interest  of economy and  convenience, and because  of the  operating
procedures  of the Fund, certificates representing  shares of the Portfolio will
not be issued. All shares  purchased are confirmed to  you and credited to  your
account  on the Fund's books  maintained by the Adviser  or its agents. You will
have  the  same  rights  and  ownership  with  respect  to  such  shares  as  if
certificates had been issued.
 
    To  ensure that checks are collected by the Fund, withdrawals of investments
made by check  are not presently  permitted until payment  for the purchase  has
been  received,  which may  take up  to eight  business days  after the  date of
purchase. As a  condition of this  offering, if  a purchase is  canceled due  to
nonpayment or because your check does not clear, you will be responsible for any
loss  the Fund or its  agents incur. If you are  already a shareholder, the Fund
may redeem shares from your account(s) to  reimburse the Fund or its agents  for
any  loss. In addition, you  may be prohibited or  restricted from making future
investments in the Fund.
 
   
    Investors may  also invest  in the  Fund by  purchasing shares  through  the
Distributor.
    
 
EXCESSIVE TRADING
 
   
    Frequent   trades  involving  either  substantial   portfolio  assets  or  a
substantial portion of your  account or accounts controlled  by you can  disrupt
management  of  the  Portfolio  and raise  its  expenses.  Consequently,  in the
interest  of  all  the  stockholders  of  the  Portfolio  and  the   Portfolio's
performance,  the Fund may in  its discretion bar a  stockholder that engages in
excessive trading of shares of any  class of a portfolio from further  purchases
of  shares of the  Fund for an  indefinite period. The  Fund considers excessive
trading to be more than one purchase and sale involving shares of the same class
of a portfolio of the Fund within any 120-day period. As an example,  exchanging
shares  of  portfolios of  the  Fund as  follows  amounts to  excessive trading:
exchanging shares of  Portfolio A  for shares  of Portfolio  B, then  exchanging
shares  of Portfolio B for shares of  Portfolio C and again exchanging shares of
Portfolio C for  shares of Portfolio  B within  a 120-day period.  Two types  of
transactions  are exempt from  these excessive trading  restrictions; (1) trades
exclusively between money market portfolios;  and (2) trades done in  connection
with  an asset allocation service,  such as TFM Accounts  or accounts managed or
advised by the Adviser and/or any of its affiliates.
    
 
   
INVESTMENT IN FUNDS THROUGH A TOTAL FUNDS MANAGEMENT ("TFM") ACCOUNT
    
 
   
    In addition to the considerable diversification among individual  securities
you  receive by investing in a particular Portfolio, you can further reduce risk
by spreading  your assets  among  several different  Portfolios that  each  have
different   risk  and  return  characteristics.  TFM  is  an  active  investment
management service managed by Morgan Stanley or its affiliates, including Morgan
Stanley Asset  Management Inc.  (each,  a "TFM  Adviser"), that  allocates  your
investments  across a combination of either Class A or Class B shares of certain
of the Portfolios selected to meet your long-term investment objectives as  well
as, in certain circumstances, your current income objectives.
    
 
   
    The TFM Adviser has developed investment strategies for TFM Accounts to meet
the  diverse financial needs of different investors.  You can open a TFM Account
by meeting with one  of the investment professionals  of a Participating  Dealer
who  will review your situation and  help you identify your long-term investment
and/or
    
 
                                       23
<PAGE>
   
current income objectives. After using TFM criteria to determine your  long-term
investment  and/or current income objectives, you  can choose one of several TFM
investment strategies. Based  on your chosen  strategy, your initial  investment
will  be  allocated among  a number  of the  Class A  or Class  B shares  of the
Portfolios.  Depending  on  market  conditions,  the  TFM  Adviser  periodically
reallocates  the combination of Portfolios or the percentage amounts invested in
the shares  of each  Portfolio to  implement your  TFM investment  strategy.  In
addition,  your TFM Account will be periodically rebalanced to maintain your TFM
strategy's current asset allocation mix, if  and when the performance of one  or
more  of the  Portfolios unbalances  the strategy's  mix. You  will pay  the TFM
Adviser a fee for the  TFM Account service that is  in addition to and  separate
from the fees and expenses you will pay directly or indirectly as an investor in
the Portfolios. See "Fund Expenses."
    
 
   
    From  time to time, one or more of the Portfolios used for investment by the
TFM Accounts may experience relatively  large investments or redemptions due  to
the  TFM Account  allocations or  rebalancings recommended  by the  TFM Adviser.
These transactions will affect the Portfolios, since Portfolios that  experience
redemptions  as  a result  of  reallocations or  rebalancings  may have  to sell
portfolio securities and Portfolios  that receive additional  cash will have  to
invest  it in additional portfolio securities. While it is impossible to predict
the overall  impact of  these transactions  over time,  there could  be  adverse
effects on portfolio management to the extent that Portfolios may be required to
sell  securities or invest  cash at times  when they would  not otherwise do so.
These transactions  could also  have  tax consequences  if sales  of  securities
resulted  in  gains  and could  also  increase transaction  costs.  The Adviser,
representing the interests  of the  Portfolios, is committed  to minimizing  the
impact of TFM Account transactions on the Portfolios. The Adviser, however, will
have  a conflict in fulfilling  this responsibility in that  it also serves as a
TFM Adviser. In that  capacity, the Adviser, representing  the interests of  the
TFM  Accounts,  also  is  committed  to minimizing  the  impact  of  TFM Account
transactions on  the  Portfolios to  the  extent consistent  with  pursuing  the
investment  objectives of the TFM Accounts. In addition, an affiliate of the TFM
Adviser, the Distributor is compensated on the sale, and may be compensated  for
distribution  or shareholder services  on the sale of  shares of the Portfolios.
See "Purchase of Shares"  and "Shareholder Services  -- Exchange Features."  The
Adviser will monitor the impact of TFM Account transactions on the Portfolios.
    
 
                              REDEMPTION OF SHARES
 
    You  may  withdraw all  or  any portion  of the  amount  in your  account by
redeeming shares at any time. Please note  that purchases made by check are  not
permitted to be redeemed until payment of the purchase price has been collected,
which  may take up to  eight business days after  purchase. The Fund will redeem
Class A shares or  Class B shares  of the Portfolio at  the next determined  net
asset  value of shares of  the applicable class. On days  that both the NYSE and
the Custodian Bank are open for business,  the net asset value per share of  the
Portfolio  is determined at the regular close  of trading of the NYSE (currently
4:00 p.m. Eastern  Time). Shares of  the Portfolio  may be redeemed  by mail  or
telephone. No charge is made for redemption. Any redemption proceeds may be more
or  less  than the  purchase  price of  your  shares depending  on,  among other
factors, the market value of the investment securities held by the Portfolio.
 
BY MAIL
 
    The Portfolio will redeem its  Class A shares or Class  B shares at the  net
asset  value determined on the  date the request is  received, if the request is
received  in  "good  order"  before  the   regular  close  of  the  NYSE.   Your
 
                                       24
<PAGE>
request should be addressed to Morgan Stanley Institutional Fund, Inc., P.O. Box
2798,  Boston,  Massachusetts 02208-2798,  except  that deliveries  by overnight
courier should  be addressed  to Morgan  Stanley Institutional  Fund, Inc.,  c/o
Chase  Global Funds Services  Company, 73 Tremont  Street, Boston, Massachusetts
02108-3913.
 
    "Good order"  means that  the  request to  redeem  shares must  include  the
following documentation:
 
        (a)   A letter of instruction or a stock assignment specifying the class
    and number  of  shares  or dollar  amount  to  be redeemed,  signed  by  all
    registered  owners  of the  shares  in the  exact  names in  which  they are
    registered;
 
        (b)  Any  required   signature  guarantees   (see  "Further   Redemption
    Information" below); and
 
        (c)    Other supporting  legal documents,  if required,  in the  case of
    estates, trusts,  guardianships, custodianships,  corporations, pension  and
    profit-sharing plans and other organizations.
 
   
    Shareholders who are uncertain of requirements for redemption should consult
with a Fund representative.
    
 
BY TELEPHONE
 
   
    Provided  you have previously elected the Telephone Redemption Option on the
Account Registration  Form, you  can  request a  redemption  of your  shares  by
calling  the Fund  and requesting  the redemption proceeds  be mailed  to you or
wired to your bank. Please contact one of the Fund's representatives for further
details. In times of drastic market conditions, the telephone redemption  option
may  be  difficult  to  implement.  If you  experience  difficulty  in  making a
telephone redemption, your request may be made by mail or express mail and  will
be  implemented at  the net  asset value next  determined after  it is received.
Redemption requests sent to the Fund through express mail must be mailed to  the
address  of the  Dividend Disbursing  and Transfer  Agent listed  under "General
Information." The Fund and the Fund's transfer agent (the "Transfer Agent") will
employ reasonable procedures  to confirm that  the instructions communicated  by
telephone  are  genuine.  These  procedures include  requiring  the  investor to
provide certain personal identification  information at the  time an account  is
opened  and  prior  to effecting  each  transaction requested  by  telephone. In
addition, all telephone transaction requests will be recorded and investors  may
be  required  to provide  additional  telecopied written  instructions regarding
transaction  requests.  Neither  the  Fund  nor  the  Transfer  Agent  will   be
responsible  for any loss, liability, cost or expense for following instructions
received by telephone that either of them reasonably believes to be genuine.
    
 
    To change the commercial  bank or account  designated to receive  redemption
proceeds,  a written  request must  be sent  to the  Fund at  the address above.
Requests to change the bank  or account must be  signed by each shareholder  and
each signature must be guaranteed.
 
FURTHER REDEMPTION INFORMATION
 
    Normally  the  Fund will  make payment  for all  shares redeemed  within one
business day of receipt  of the request,  but in no event  will payment be  made
more  than  seven days  after receipt  of  a redemption  request in  good order.
However, payments to investors  redeeming shares which  were purchased by  check
will  not be made until  payment for the purchase  has been collected, which may
take up to eight days after the date of purchase. The Fund may suspend the right
of redemption or postpone the date upon which redemptions are effected at  times
when  the NYSE is closed, or under  any emergency circumstances as determined by
the Securities and Exchange Commission (the "Commission").
 
                                       25
<PAGE>
    If the Board  of Directors determines  that it would  be detrimental to  the
best  interests of the  remaining shareholders of the  Portfolio to make payment
wholly or partly in cash, the Fund  may pay the redemption proceeds in whole  or
in part by a distribution in-kind of securities held by the Portfolio in lieu of
cash    in    conformity   with    applicable    rules   of    the   Commission.
Distributions-in-kind will be made  in readily marketable securities.  Investors
may  incur brokerage charges on the sale  of portfolio securities so received in
payment of redemptions.
 
    To protect  your account,  the Fund  and its  agents from  fraud,  signature
guarantees  are required for  certain redemptions to verify  the identity of the
person who has  authorized a redemption  from your account.  Please contact  the
Fund  for further  information. See "Redemption  of Shares" in  the Statement of
Additional Information.
 
                              SHAREHOLDER SERVICES
 
EXCHANGE FEATURES
   
    You may exchange  shares that you  own in  the Portfolio for  shares of  any
other  available portfolio(s) of  the Fund (other  than the International Equity
Portfolio, which is  closed to  new investors). In  exchanging for  shares of  a
portfolio  with more  than one  class, the  class of  shares you  receive in the
exchange will be determined in the same  manner as any other purchase of  shares
and  will not  be based  on the  class of  shares surrendered  for the exchange.
Consequently, the same minimum initial  investment and minimum account size  for
determining  the  class  of shares  received  in  the exchange  will  apply. See
"Purchase of  Shares." Shares  of the  portfolios may  be exchanged  by mail  or
telephone.  The privilege to exchange shares  by telephone is automatic and made
available without shareholder election. Before you make an exchange, you  should
read  the prospectus of the portfolio(s) in which you seek to invest. Because an
exchange transaction  is treated  as a  redemption followed  by a  purchase,  an
exchange  would be considered  a taxable event for  shareholders subject to tax.
The exchange privilege may  be modified or  terminated by the  Fund at any  time
upon 60-days notice to shareholders.
    
 
BY MAIL
 
   
    In  order to  exchange shares  by mail, you  should include  in the exchange
request the name, class of shares and account number of your current  Portfolio,
the name(s) of the portfolio(s) and class(es) of shares into which you intend to
exchange  shares, and the signatures of all registered account holders. Send the
exchange request  to Morgan  Stanley Institutional  Fund, Inc.,  P.O. Box  2798,
Boston, Massachusetts 02208-2798.
    
 
BY TELEPHONE
 
   
    When  exchanging shares by  telephone, have ready the  name, class of shares
and account number of  the current portfolios, the  name(s) of the  portfolio(s)
and  class(es) of shares into  which you intend to  exchange shares, your Social
Security number  or Tax  I.D. number,  and your  account address.  Requests  for
telephone  exchanges received prior to 4:00 p.m. (Eastern Time) are processed at
the close  of business  that  same day  based  on the  net  asset value  of  the
class(es) of the portfolio(s) involved in the exchange of shares at the close of
business.  Requests received  after 4:00 p.m.  (Eastern Time)  are processed the
next business  day based  on the  net asset  value determined  at the  close  of
business  on such day.  For additional information  regarding responsibility for
the authenticity of  telephoned instructions,  see "Redemption of  Shares --  By
Telephone" above.
    
 
                                       26
<PAGE>
TRANSFER OF REGISTRATION
 
   
    You may transfer the registration of any of your Portfolio shares to another
person  by writing  to Morgan Stanley  Institutional Fund, Inc.,  P.O. Box 2798,
Boston, Massachusetts 02208-2798.  As in  the case of  redemptions, the  written
request  must  be  received in  good  order  before any  transfer  can  be made.
Transferring the  registration of  shares  may affect  the eligibility  of  your
account  for  a  given  class  of  the  Portfolio's  shares  and  may  result in
involuntary conversion or redemption  of your shares.  See "Purchase of  Shares"
above.
    
 
                              VALUATION OF SHARES
 
   
    The  net asset  value per  share of a  class of  shares of  the Portfolio is
determined by dividing the total market value of the Portfolio's investments and
other assets attributable to  such class, less  any liabilities attributable  to
such  class, by  the total  number of  outstanding shares  of each  class of the
Portfolio. Net  asset value  is  calculated separately  for  each class  of  the
Portfolio.  Net asset value per  share is determined as  of the regular close of
the NYSE on each day  that the NYSE is open  for business. Price information  on
listed  securities is  taken from the  exchange where the  security is primarily
traded. Securities  listed  on  a  U.S. securities  exchange  for  which  market
quotations are available are valued at the last quoted sale price on the day the
valuation  is made. Securities listed on a  foreign exchange are valued at their
closing price.  Unlisted securities  and  listed securities  not traded  on  the
valuation date for which market quotations are readily available are valued at a
price  within a range  not exceeding the  current asked price  nor less than the
current bid price. The current bid and asked prices are determined based on  the
average  of the bid and asked prices  quoted on such valuation date by reputable
brokers.
    
 
   
    Bonds and other fixed income securities are valued according to the broadest
and most representative  market, which will  ordinarily be the  over-the-counter
market.  Net asset value includes interest  on fixed income securities, which is
accrued daily.  In addition,  bonds and  other fixed  income securities  may  be
valued on the basis of prices provided by a pricing service when such prices are
believed  to  reflect  the fair  market  value  of such  securities.  The prices
provided by a pricing service are determined without regard to bid or last  sale
prices  but take into  account institutional size, trading  in similar groups of
securities and any developments related  to the specific securities.  Securities
not  priced in this manner are valued at  the most recently quoted bid price or,
when securities exchange valuations are used, at the latest quoted sale price on
the day of valuation. If there is  no such reported sale, the latest quoted  bid
price will be used. Securities purchased with remaining maturities of 60 days or
less are valued at amortized cost, if it approximates market value. In the event
that  amortized  cost  does  not  approximate  market  value,  market  prices as
determined above will be used.
    
 
   
    The value  of other  assets  and securities  for  which quotations  are  not
readily  available (including  restricted and  unlisted foreign  securities) and
those securities for which it is inappropriate to determine prices in accordance
with the above-stated  procedures are  determined in  good faith  at fair  value
using  methods determined by the Board of Directors. For purposes of calculating
net asset value  per share, all  assets and liabilities  initially expressed  in
foreign  currencies will be translated into U.S.  dollars at the mean of the bid
and asked price of such  currencies against the U.S.  dollar last quoted by  any
major bank.
    
 
    Although  the legal rights of Class A  and Class B shares will be identical,
the different expenses borne  by each class will  result in different net  asset
values    and   dividends   for   the    class.   Dividends   will   differ   by
 
                                       27
<PAGE>
approximately the amount of the distribution expense accrual differential  among
the  classes. The net asset value of Class B shares will generally be lower than
the net  asset value  of the  Class A  shares as  a result  of the  distribution
expense charged to Class B shares.
 
                            PERFORMANCE INFORMATION
 
    The  Fund may from time  to time advertise "total  return" for each class of
the Portfolio.  THESE FIGURES  ARE  BASED ON  HISTORICAL  EARNINGS AND  ARE  NOT
INTENDED TO INDICATE FUTURE PERFORMANCE.
 
   
    The Portfolio may advertise "total return" which shows what an investment in
a class of the Portfolio would have earned over a specified period of time (such
as  one, five or ten years) assuming that all distributions and dividends by the
Portfolio were reinvested in the same class on the reinvestment dates during the
period. Total return  does not  take into account  any federal  or state  income
taxes  that may be payable on dividend and distributions or upon redemption. The
Fund may  also include  comparative performance  information in  advertising  or
marketing  the Portfolio's shares. Such performance information may include data
from Lipper  Analytical Services,  Inc., other  industry publications,  business
periodicals, rating services and market indices.
    
 
    The  performance figures  for Class  B shares  will generally  be lower than
those for Class  A shares because  of the  distribution fee charged  to Class  B
shares.
 
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
 
   
    All  income dividends and capital gains  distributions for a class of shares
will be automatically reinvested in additional shares of such class at net asset
value, except that,  upon written  notice to  the Fund  or by  checking off  the
appropriate  box in the Distribution Option  Section on the Account Registration
Form, a shareholder  may elect  to receive  income dividends  and capital  gains
distributions in cash.
    
 
   
    The  Portfolio expects  to distribute substantially  all of  its taxable net
investment income  in the  form  of quarterly  dividends. Net  realized  capital
gains,  if any,  after reduction for  any available tax  loss carryforwards will
also be distributed annually.
    
 
   
    Undistributed net  investment  income is  included  in the  Portfolio's  net
assets  for the purpose of calculating net  asset value per share. Therefore, on
the "ex-dividend" date,  the net  asset value  per share  excludes the  dividend
(i.e.,  is reduced  by the  per share  amount of  the dividend).  Dividends paid
shortly after the purchase of shares by an investor, although in effect a return
of capital, are taxable to shareholders subject to income tax.
    
 
   
    Because of  the  distribution  fee  and  any  other  expenses  that  may  be
attributable  to the  Class B  shares, the  net income  attributable to  and the
dividends payable  on  Class  B  shares  will  be  lower  than  the  net  income
attributable  to and the dividends  payable on Class A  shares. As a result, the
net asset value per share of the classes of the Portfolio will differ at  times.
Expenses  of the  Portfolio allocated  to a particular  class of  shares will be
borne on a pro rata basis by each outstanding share of that class.
    
 
                                     TAXES
 
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
 
                                       28
<PAGE>
    No attempt has been made to  present a detailed explanation of the  federal,
state,  or  local income  tax treatment  of the  Portfolio or  its shareholders.
Accordingly, shareholders  are urged  to consult  their tax  advisors  regarding
specific questions as to federal, state and local income taxes.
 
   
    The  Portfolio  is  treated as  a  separate  entity for  federal  income tax
purposes and is  not combined with  the Fund's other  portfolios. The  Portfolio
intends  to qualify for the special  tax treatment afforded regulated investment
companies under Subchapter M of the Code so that the Portfolio will be  relieved
of  federal income tax on that part of its net investment income and net capital
gain that is distributed to shareholders.
    
 
   
    The Portfolio intends  to distribute  substantially all of  its taxable  net
investment  income (including, for this purpose, net short-term capital gain) to
shareholders. Dividends from the Portfolio's  net investment income are  taxable
to  shareholders as ordinary  income, whether received in  cash or in additional
shares. Such dividends  will generally  qualify for  the 70%  dividends-received
deduction  for  corporate  shareholders  only to  the  extent  of  the aggregate
qualifying dividend income received by the Portfolio from U.S. corporations. The
Portfolio will report annually to its shareholders the amount of dividend income
qualifying for such treatment.
    
 
   
    Distributions of net capital gain (the excess of net long-term capital  gain
over  net  short-term capital  loss) are  taxable  to shareholders  as long-term
capital gain, regardless of  how long shareholders have  held their shares.  The
Portfolio  will send reports annually to  shareholders of the federal income tax
status of all distributions made during the preceding year.
    
 
   
    The  Portfolio   intends  to   make  sufficient   distributions  or   deemed
distributions  of its ordinary income and capital gain net income (the excess of
short-term and  long-term capital  gain over  short-term and  long-term  capital
losses,  including any available capital loss carryforwards) prior to the end of
each calendar year to avoid liability for federal excise tax.
    
 
    Dividends and  other distributions  declared by  the Portfolio  in  October,
November or December of any year and payable to shareholders of record on a date
in  such month will be deemed to have been paid by the Portfolio and received by
the shareholders on December 31  of that year if  the distributions are paid  by
the Portfolio at any time during the following January.
 
   
    The  Fund may be required to withhold and  remit to the U.S. Treasury 31% of
any dividends, capital gains distributions  and redemption proceeds paid to  any
individual  or certain  other non-corporate  shareholder (1)  who has  failed to
provide a  correct taxpayer  identification  number (generally  an  individual's
social  security number  or non-individual's employer  identification number) on
the Application Form, (2) who is  subject to backup withholding by the  Internal
Revenue  Service, or (3) who has not certified to the Fund that such shareholder
is not  subject  to  backup  withholding. This  backup  withholding  is  not  an
additional   tax,  and  any  amounts  withheld   may  be  credited  against  the
shareholder's ultimate U.S. tax liability.
    
 
   
    The sale, exchange or  redemption of shares will  result in taxable gain  or
loss to the selling, exchanging or redeeming shareholder, depending upon whether
the  fair market value  of the redemption  proceeds exceed or  are less than the
shareholder's adjusted  basis in  the  sold, exchanged  or redeemed  shares.  If
capital  gain distributions have been made with  respect to shares that are sold
at a loss after being held for six months or less, then the loss is treated as a
long-term capital loss to the extent of the capital gain distributions.
    
 
   
    Conversion  of  shares  between  classes  are  not  taxable  events  to  the
Shareholder.
    
 
                                       29
<PAGE>
    Shareholders  are urged  to consult with  their tax  advisors concerning the
application of state  and local income  taxes to investments  in the  Portfolio,
which may differ from the federal income tax consequences described above.
 
    Investment  income  received by  the Portfolio  from sources  within foreign
countries may be subject to foreign income taxes withheld at the source. To  the
extent  that the Portfolio is  liable for foreign income  taxes so withheld, the
Portfolio intends to operate so as to meet the requirements of the Code to  pass
through  to the shareholders credit for  foreign income taxes paid. Although the
Portfolio intends to  meet Code  requirements to  pass through  credit for  such
taxes, there can be no assurance that the Portfolio will be able to do so.
 
   
    THE TAX DISCUSSION SET FORTH ABOVE IS INCLUDED FOR GENERAL INFORMATION ONLY.
PROSPECTIVE  INVESTORS SHOULD CONSULT THEIR OWN TAX ADVISERS WITH RESPECT TO THE
TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN THE PORTFOLIO.
    
 
   
                             PORTFOLIO TRANSACTIONS
    
 
   
    The Adviser selects the brokers or  dealers that will execute the  purchases
and  sales  of investment  securities  for each  of  the Fund's  portfolios. The
Adviser seeks the best execution of all portfolio transactions. A portfolio  may
pay  higher commission rates than the lowest available when the Adviser believes
it is reasonable to do  so in light of the  value of the research,  statistical,
and pricing services provided by the broker effecting the transaction.
    
 
   
    It is not the Fund's practice to allocate brokerage or principal business on
the  basis of sales of shares which  may be made through intermediary brokers or
dealers. However, the Adviser may,  consistent with NASD rules, place  portfolio
orders  with qualified broker-dealers who  recommend the applicable portfolio to
their clients or who act  as agents in the purchase  of shares of the  portfolio
for their clients.
    
 
   
    Subject  to  the overriding  objective of  obtaining  the best  execution of
orders, the  Fund may  use broker-dealer  affiliates of  the Adviser,  including
Morgan  Stanley,  to effect  portfolio  brokerage transactions  under procedures
adopted by the Fund's Board of Directors. For such transactions, the  commission
rates  and other remuneration paid to Morgan Stanley or other affiliates must be
fair  and  reasonable  in  comparison  to  those  of  other  broker-dealers  for
comparable  transactions involving  similar securities  being purchased  or sold
during a comparable time period.
    
 
   
PORTFOLIO TURNOVER
    
 
   
    The Portfolio generally  does not  invest for  short-term trading  purposes,
however,   when  circumstances  warrant,  the   Portfolio  may  sell  investment
securities without regard  to the  length of time  they have  been held.  Market
conditions  in a given year could result in a higher or lower portfolio turnover
rate than expected and the Portfolio will not consider portfolio turnover rate a
limiting factor in  making investment decisions  consistent with its  respective
objective   and  policies.  As  portfolio   turnover  increases,  the  Portfolio
necessarily  will  experience   increased  transaction   costs  and   additional
realization of capital gains.
    
 
                                       30
<PAGE>
                              GENERAL INFORMATION
 
DESCRIPTION OF COMMON STOCK
 
   
    The  Fund was  organized as  a Maryland  corporation on  June 16,  1988. The
Articles of Incorporation, as amended and restated, permit the Fund to issue  up
to  35 billion shares of common stock,  with $.001 par value per share. Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number of shares the  Fund is authorized  to issue without  the approval of  the
shareholders  of the Fund. The Board of Directors has the power to designate one
or more classes of  shares of common  stock and to  classify and reclassify  any
unissued shares with respect to such classes. The shares of common stock of each
portfolio  are currently classified into two classes, the Class A shares and the
Class B  shares,  except for  the  International  Small Cap,  Money  Market  and
Municipal Money Market Portfolios which offer only Class A shares.
    
 
   
    The shares of the Portfolio, when issued, will be fully paid, nonassessable,
fully  transferable and redeemable at the option  of the holder. The shares have
no preference  as  to  conversion,  exchange,  dividends,  retirement  or  other
features  and  have no  pre-emptive  rights. The  shares  of the  Portfolio have
non-cumulative voting rights, which means that  the holders of more than 50%  of
the  shares voting for the election of Directors can elect 100% of the Directors
if they choose  to do so.  Persons or organizations  owning 25% or  more of  the
outstanding  shares of a portfolio may be presumed to "control" (as that term is
defined in the 1940  Act) that Portfolio.  Under Maryland law,  the Fund is  not
required  to hold an annual meeting of its shareholders unless required to do so
under the 1940 Act.
    
 
REPORTS TO SHAREHOLDERS
 
    The Fund will send to its  shareholders annual and semi-annual reports;  the
financial  statements  appearing in  annual reports  are audited  by independent
accountants. Monthly unaudited portfolio  data is also  available from the  Fund
upon request.
 
    In  addition, the Adviser or its agent, as Transfer Agent, will send to each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
 
   
CUSTODIAN
    
 
   
    Chase is the Fund's custodian for domestic and certain foreign assets. Chase
is not an  affiliate of  the Adviser or  the Distributor.  Morgan Stanley  Trust
Company,  Brooklyn,  New York,  ("MSTC"), an  affiliate of  the Adviser  and the
Distributor, acts as  the Fund's custodian  for assets held  outside the  United
States  and employs subcustodians approved by the Board of Directors of the Fund
in accordance with regulations of the Securities and Exchange Commission for the
purpose of providing  custodial services  for such  assets. MSTC  may also  hold
certain  domestic assets for  the Fund. For more  information on the custodians,
see "General Information -- Custody Arrangements" in the Statement of Additional
Information.
    
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
    Chase  Global   Funds  Services   Company,   73  Tremont   Street,   Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
 
                                       31
<PAGE>
INDEPENDENT ACCOUNTANTS
 
   
    Price  Waterhouse LLP  serves as  independent accountants  for the  Fund and
audits its annual financial statements.
    
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       32
<PAGE>
   MORGAN STANLEY INSTITUTIONAL FUND, INC.
          GOLD PORTFOLIO
           P.O. BOX 2798, BOSTON, MA 02208-2798
 
                           ACCOUNT REGISTRATION FORM
 
<TABLE>
<C>   <S>                        <C>
                                 If you need assistance in filling out this form for the
      ACCOUNT INFORMATION        Morgan Stanley Institutional Fund, please contact your
      Fill in where applicable   Morgan Stanley representative or call us toll free
                                 1-(800)-548-7786. Please print all items except signature,
                                 and mail to the Fund at the address above.
 
  A)  REGISTRATION
      1. INDIVIDUAL
      2. JOINT TENANTS
         (RIGHTS OF
      SURVIVORSHIP PRESUMED
      UNLESS
         TENANCY IN COMMON
         IS INDICATED)
</TABLE>
 
1.
                               First
Name                          Initial                               Last Name
 
2.
                               First
Name                          Initial                               Last Name
 
                               First
Name                          Initial                               Last Name
 
<TABLE>
<C>   <S>                        <C>
      3. CORPORATIONS,
         TRUSTS AND OTHERS
         Please call the Fund
      for additional documents
      that may be required to
      set up account and to
      authorize transactions.
</TABLE>
 
3.
 
<TABLE>
<S>                     <C>                 <C>                   <C>               <C>
Type of Registration:   / / INCORPORATED    / / UNINCORPORATED    / / PARTNERSHIP   / / UNIFORM GIFT/TRANSFER TO MINOR
                                            ASSOCIATION                               (ONLY ONE CUSTODIAN AND MINOR PERMITTED)
</TABLE>
 
/ / TRUST ________________________  / / OTHER (Specify) ________________________
 
<TABLE>
<C>   <S>                                            <C>
  B)  MAILING ADDRESS
      Please fill in completely, including
      telephone number(s).
</TABLE>
 
   
/ / United States Citizen  / / Resident Alien
    
   
                   Street or P.O. Box
    
   
                   City
    
                   State                   Zip
   
Home Telephone No.                   Business Telephone No.
    
 
   
/ / Non-Resident Alien:
    
 
   
Permanent Address (Where you reside permanently for tax purposes)
    
   
                   Street Address
    
   
                   City
    
                   Country                   Postal Code
   
Home Telephone No.                    Business Telephone No.
    
 
   
Current Mailing Address (If different from Permanent Address)
    
   
                   Street Address
    
   
                   City
    
                   Country
   
Postal Code
    
   
Home Telephone No.                   Business Telephone No.
    
 
<TABLE>
<S>   <S>                        <C>                             <C>
  C)  TAXPAYER                   Enter your Taxpayer Identification Number. For most individual
      IDENTIFICATION             taxpayers, this is your Social Security Number.
      NUMBER
      1. INDIVIDUAL
      2. JOINT TENANTS
         (RIGHTS OF
      SURVIVORSHIP PRESUMED
      UNLESS
         TENANCY IN COMMON
         IS INDICATED)
</TABLE>
<PAGE>
<TABLE>
<S>   <S>                        <C>                             <C>
      For Custodian account
      of a minor (Uniform
      Gifts/Transfers to Minor
      Acts), give the Social
      Security Number of
      the minor
                                                                 OR
                                 1.         TAXPAYER             SOCIAL SECURITY NUMBER
                                 IDENTIFICATION NUMBER           ("SSN")
                                 ("TIN")
                                                                 OR
                                 2.                                                          TIN                                SSN
                                                                 OR
                                                               TIN                                SSN
 
                                 IMPORTANT TAX INFORMATION
                                 You (as a payee) are required by law to provide us (as  payer)
                                 with  your  correct TIN(s)  or  SSN(s). Accounts  that  have a
                                 missing or  incorrect  TIN(s) or  SSN(s)  will be  subject  to
                                 backup  withholding at a 31%  rate on dividends, distributions
                                 and other  payments. If  you have  not provided  us with  your
                                 correct  TIN(s) or SSN(s), you may be subject to a $50 penalty
                                 imposed by the Internal Revenue Service.
                                 Backup withholding is not an additional tax; the tax liability
                                 of persons subject  to backup withholding  will be reduced  by
                                 the  amount  of tax  withheld.  If withholding  results  in an
                                 overpayment   of   taxes,   a   refund   may   be    obtained.
                                 You may be notified that you are subject to backup withholding
                                 under  Section  3406(a)(1)(C)  of  the  Internal  Revenue Code
                                 because you have  underreported interest or  dividends or  you
                                 were  required to,  but failed to,  file a  return which would
                                 have included a reportable interest or dividend payment.
</TABLE>
 
<PAGE>
 
   
<TABLE>
<C>   <S>                        <C>                             <C>                   <C>
  D)  PORTFOLIO AND              For Purchase of the following   / / Class A Shares $  / / Class B Shares $
      CLASS SECTION              Portfolio:
      (Class A shares minimum    Gold Portfolio
      $500,000 for the
      Portfolio and Class B
      shares minimum $100,000
      for the Portfolio).
      Please indicate class and
      amount.
                                                                 Total Initial Investment $
</TABLE>
    
 
<TABLE>
<C>   <S>                        <C>
  E)  METHOD OF
      INVESTMENT
      Please indicate
      portfolio, manner of
      payment.
</TABLE>
 
Payment by:
 
/ / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND,
INC.--PORTFOLIO NAME)
 
<TABLE>
<S>                                                                                 <C>
/ / Exchange $ From                                                                           -- - - - - - - - - - -- - -
                                                      Name of Portfolio                               Account No.
/ / Account previously established by:  / / Phone exchange  / / Wire on                       -- - - - - - - - - - -- - -
                                                                                            Account No.               (Check
                                                                                      (Previously assigned by the Fund)     Digit)
                                                                            Date
</TABLE>
 
<TABLE>
<C>   <S>                        <C>
  F)  DISTRIBUTION               Income dividends and capital gains distributions (if any) to
      OPTION                     be reinvested in additional shares unless either box below
                                 is checked.
                                 / / Income dividends to be paid in cash, capital gains
                                 distributions (if any) in shares.
                                 / / Income dividends and capital gains distributions (if
                                 any) to be paid in cash.
</TABLE>
 
<TABLE>
<C>   <S>                             <C>                                       <C>
  G)  TELEPHONE                       / / I/we hereby authorize the Fund and
      REDEMPTION                      its agents to honor any telephone         Name of COMMERCIAL Bank (Not Savings
      AND EXCHANGE                    requests to wire redemption proceeds to   Bank)
      OPTION                          the commercial bank indicated at right    Bank Account No.
      Please select at time of        and/or mail redemption proceeds to the
      initial application if you      name and address in which my/our fund
      wish to redeem or exchange      account is registered if such requests                                        Bank
      shares by telephone. A          are believed to be authentic.                                                  ABA
      SIGNATURE GUARANTEE IS          The Fund and the Fund's Transfer Agent                                         No.
      REQUIRED IF BANK ACCOUNT IS     will employ reasonable procedures to
      NOT REGISTERED IDENTICALLY TO   confirm that instructions communicated    Name(s) in which your BANK Account is
      YOUR FUND ACCOUNT.              by telephone are genuine. These           Established
      TELEPHONE REQUESTS FOR          procedures include requiring the
      REDEMPTIONS OR EXCHANGE WILL    investor to provide certain personal      Bank's Street
      NOT BE HONORED UNLESS THE BOX   identification information at the time    Address
      IS CHECKED.                     an account is opened and prior to
                                      effecting each transaction requested by   City        State Zip
                                      telephone. In addition, all telephone
                                      transaction requests will be recorded
                                      and investors may be required to provide
                                      additional telecopied written
                                      instructions of transaction requests.
                                      Neither the Fund nor the Transfer Agent
                                      will be responsible for any loss,
                                      liability, cost or expense for following
                                      instructions received by telephone that
                                      it reasonably believes to be genuine.
</TABLE>
 
   
<TABLE>
<C>   <S>                        <C>
  H)  INTERESTED PARTY
      OPTION                                                                                      Name
      In addition to the
      account statement sent to
      my/our registered                                                                          Address
      address, I/we hereby
      authorize the Fund to        City                                         State                                         Z
      mail duplicate statements  Code
      to the name and address
      provided at right.
</TABLE>
    
 
<TABLE>
<C>   <S>                        <C>
  I)  DEALER
      INFORMATION
                                 Representative Name                        Representative
                                 No.                            Branch
                                 No.
</TABLE>
 
<PAGE>
 
<TABLE>
<C>   <S>                        <C>
  J)  SIGNATURE OF
      ALL HOLDERS
      AND TAXPAYER
      CERTIFICATION
      Sign Here ,
</TABLE>
 
   
<TABLE>
<S>                                  <C>
The undersigned certify that I/we have full authority and legal capacity
to purchase and redeem shares of the Fund and affirm that I/we have
received a current Prospectus of the Morgan Stanley Institutional Fund,
Inc. and agree to be bound by its terms.
  BY SIGNING THIS  APPLICATION, I/WE HEREBY  CERTIFY UNDER PENALTIES  OF
PERJURY THAT THE INFORMATION ON THIS APPLICATION IS COMPLETE AND CORRECT
AND  THAT  AS REQUIRED  BY FEDERAL  LAW  (PLEASE CHECK  APPLICABLE BOXES
BELOW):
/ / U.S. CITIZEN(S)/TAXPAYER(S):
       / / I/WE CERTIFY THAT (1) THE NUMBER(S) SHOWN ABOVE ON THIS  FORM
           IS/ARE  THE CORRECT  SSN(S) OR  TIN(S) AND  (2) I/WE  ARE NOT
           SUBJECT TO ANY BACKUP WITHHOLDING EITHER BECAUSE (A) I/WE ARE
           EXEMPT FROM  BACKUP  WITHHOLDING;  (B)  I/WE  HAVE  NOT  BEEN
           NOTIFIED  BY THE  INTERNAL REVENUE SERVICE  ("IRS") THAT I/WE
           ARE SUBJECT TO BACKUP WITHHOLDING AS A RESULT OF A FAILURE TO
           REPORT ALL INTEREST OR DIVIDENDS; OR (C) THE IRS HAS NOTIFIED
           ME/US  THAT  I  AM/WE  ARE   NO  LONGER  SUBJECT  TO   BACKUP
           WITHHOLDING.
       /  / IF  NO TIN(S) OR  SSN(S) HAS/HAVE BEEN  PROVIDED ABOVE, I/WE
           HAVE APPLIED, OR INTEND  TO APPLY, TO THE  IRS OR THE  SOCIAL
           SECURITY   ADMINISTRATION  FOR  A  TIN  OR  A  SSN  AND  I/WE
           UNDERSTAND THAT IF I/WE DO NOT PROVIDE EITHER NUMBER TO CHASE
           GLOBAL FUNDS SERVICES COMPANY ("CGFSC") WITHIN 60 DAYS OF THE
           DATE OF THIS APPLICATION  OR IF I/WE  FAIL TO FURNISH  MY/OUR
           CORRECT  SSN(S) OR TIN(S),  I/WE MAY BE  SUBJECT TO A PENALTY
           AND A 31% BACKUP WITHHOLDING ON DISTRIBUTIONS AND  REDEMPTION
           PROCEEDS. (PLEASE PROVIDE EITHER NUMBER ON IRS FORM W-9). YOU
           MAY REQUEST SUCH FORM BY CALLING CGFSC AT 800-282-4404.
/ / NON-U.S. CITIZEN(S)/TAXPAYER(S):
  UNDER  PENALTIES  OF  PERJURY, I/WE  CERTIFY  THAT I/WE  ARE  NOT U.S.
CITIZENS OR RESIDENTS AND I/WE ARE EXEMPT FOREIGN PERSONS AS DEFINED  BY
THE INTERNAL REVENUE SERVICE.
 
THE  INTERNAL  REVENUE  SERVICE DOES  NOT  REQUIRE YOUR  CONSENT  TO ANY
PROVISION OF THIS  DOCUMENT OTHER  THAN THE  CERTIFICATIONS REQUIRED  TO
AVOID BACKUP WITHHOLDING.
 
                                     (X)
(X)                                  Signature (if joint account, both
Signature                                                                     Date must sign)         Date
</TABLE>
    
<PAGE>
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
 
  NO  DEALER, SALES  REPRESENTATIVE OR ANY  OTHER PERSON HAS  BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE  CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS  HAVING BEEN AUTHORIZED BY THE FUND  OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF  THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION  TO
ANY  PERSON TO WHOM  IT IS UNLAWFUL TO  MAKE SUCH OFFER  OR SOLICITATION IN SUCH
JURISDICTION.
                           --------------------------
 
                               TABLE OF CONTENTS
 
   
<TABLE>
<S>                                                 <C>
                                                    PAGE
                                                    ----
Fund Expenses.....................................    2
Financial Highlights..............................    4
Prospectus Summary................................    6
Investment Objective and Policies.................   10
Additional Investment Information.................   11
Investment Limitations............................   17
Management of the Fund............................   17
Purchase of Shares................................   19
Redemption of Shares..............................   24
Shareholder Services..............................   26
Valuation of Shares...............................   27
Performance Information...........................   28
Dividends and Capital Gains Distributions.........   28
Taxes.............................................   28
Portfolio Transactions............................   30
General Information...............................   31
Account Registration Form
</TABLE>
    
 
                                 GOLD PORTFOLIO
                               A PORTFOLIO OF THE
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
 
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Sub-Adviser
                            Sun Valley Gold Company
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
 
- ---------------------------------
- ---------------------------------
- ---------------------------------
- ---------------------------------
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
- --------------------------------------------------------------------------------
 
                            GLOBAL EQUITY PORTFOLIO
                         INTERNATIONAL EQUITY PORTFOLIO
                       INTERNATIONAL SMALL CAP PORTFOLIO
                             ASIAN EQUITY PORTFOLIO
                           EUROPEAN EQUITY PORTFOLIO
                           JAPANESE EQUITY PORTFOLIO
                            LATIN AMERICAN PORTFOLIO
 
                               PORTFOLIOS OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
 
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
                                ----------------
 
   
    Morgan Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company, or mutual fund, which offers redeemable shares in
a series of diversified and non-diversified investment portfolios
("portfolios"). The Fund is designed to provide clients with attractive
alternatives for meeting their investment needs. The Fund currently consists of
twenty-nine portfolios representing a broad range of investment choices. This
prospectus (the "Prospectus") pertains to the Class A and the Class B shares of
the Global Equity, International Equity, Asian Equity, European Equity, Japanese
Equity and Latin American Portfolios (each a "Multiclass Portfolio" and
collectively, the "Multiclass Portfolios") and to the Class A Shares of the
International Small Cap Portfolio (each, a "Portfolio" and collectively, the
"Portfolios"). The International Equity Portfolio is currently closed to new
investors with the exception of certain Morgan Stanley & Co. Incorporated
("Morgan Stanley") customers. The Class A and Class B shares currently offered
by the Portfolios have different minimum investment requirements and fund
expenses. Shares of the portfolios are offered with no sales charge, exchange
fee or redemption fee, (except that the International Small Cap Portfolio may
impose a transaction fee).
    
 
    The Fund is designed to meet the investment needs of discerning investors
who place a premium on quality and personal service. With Morgan Stanley Asset
Management Inc. as Adviser and Administrator (the "Adviser" and the
"Administrator"), and with Morgan Stanley as Distributor, the Fund makes
available to institutional and high net worth individual investors a series of
portfolios which benefit from the investment expertise and commitment to
excellence associated with Morgan Stanley and its affiliates.
 
    This Prospectus is designed to set forth concisely the information about the
Fund that a prospective investor should know before investing and it should be
retained for future reference. The Fund offers additional portfolios which are
described in other prospectuses and under "Prospectus Summary" below. The Fund
currently offers the following portfolios: (i) GLOBAL AND INTERNATIONAL EQUITY
- -- Active Country Allocation, Asian Equity, Emerging Markets, European Equity,
Global Equity, Gold, International Equity, International Magnum, International
Small Cap, Japanese Equity and Latin American Portfolios; (ii) U.S. EQUITY --
Aggressive Equity, Emerging Growth, Equity Growth, Small Cap Value Equity,
Technology, U.S. Real Estate and Value Equity Portfolios; (iii) EQUITY AND FIXED
INCOME -- Balanced Portfolio; (iv) FIXED INCOME -- Emerging Markets Debt, Fixed
Income, Global Fixed Income, High Yield and Municipal Bond Portfolios; and (v)
MONEY MARKET -- Money Market and Municipal Money Market Portfolios. Additional
information about the Fund is contained in a "Statement of Additional
Information," dated May 1, 1997, which is incorporated herein by reference. The
Statement of Additional Information and the prospectuses pertaining to the other
portfolios of the Fund are available upon request and without charge by writing
or calling the Fund at the address and telephone number set forth above.
 
 THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES AND
   EXCHANGE COMMISSION, NOR HAS THE SECURITIES AND EXCHANGE COMMISSION
    PASSED UPON THE ACCURACY OR ADEQUACY OF THIS PROSPECTUS. ANY
             REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.
 
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1997.
<PAGE>
                                 FUND EXPENSES
 
    The following table illustrates the expenses and fees that a shareholder of
each Portfolio listed below will incur.
<TABLE>
<CAPTION>
                                                GLOBAL EQUITY   INTERNATIONAL EQUITY   INTERNATIONAL SMALL    ASIAN EQUITY
SHAREHOLDER TRANSACTION EXPENSES                  PORTFOLIO           PORTFOLIO           CAP PORTFOLIO         PORTFOLIO
- ---------------------------------------------  ---------------  ---------------------  -------------------  -----------------
<S>                                            <C>              <C>                    <C>                  <C>
Maximum Sales Load Imposed on Purchases
  Class A....................................          None                None                  None*               None
  Class B....................................          None                None                   N/A                None
Maximum Sales Load Imposed on Reinvested
 Dividends
  Class A....................................          None                None                  None                None
  Class B....................................          None                None                   N/A                None
Deferred Sales Load
  Class A....................................          None                None                  None                None
  Class B....................................          None                None                   N/A                None
Redemption Fees
  Class A....................................          None                None                  1.00%*              None
  Class B....................................          None                None                   N/A                None
Exchange Fees
  Class A....................................          None                None                  None                None
  Class B....................................          None                None                   N/A                None
 
<CAPTION>
 
                                                                   EUROPEAN EQUITY       JAPANESE EQUITY     LATIN AMERICAN
SHAREHOLDER TRANSACTION EXPENSES                                      PORTFOLIO             PORTFOLIO           PORTFOLIO
- ---------------------------------------------                   ---------------------  -------------------  -----------------
<S>                                            <C>              <C>                    <C>                  <C>
Maximum Sales Load Imposed on Purchases
  Class A.....................................................             None                  None                None
  Class B.....................................................             None                  None                None
Maximum Sales Load Imposed on Reinvested Dividends
  Class A.....................................................             None                  None                None
  Class B.....................................................             None                  None                None
Deferred Sales Load
  Class A.....................................................             None                  None                None
  Class B.....................................................             None                  None                None
Redemption Fees
  Class A.....................................................             None                  None                None
  Class B.....................................................             None                  None                None
Exchange Fees
  Class A.....................................................             None                  None                None
  Class B.....................................................             None                  None                None
</TABLE>
 
- --------------------------
   
* Shareholders of the International Small Cap Portfolio may be charged a 1.00%
  transaction fee, which is payable directly to the International Small Cap
  Portfolio, in connection with each purchase and redemption of shares of the
  Portfolio. The transaction fee is intended to allocate transaction costs
  associated with purchases and redemptions of shares of the Portfolio to
  investors actually making such purchases and redemptions rather than to the
  Portfolio's other shareholders. The 1.00% fee represents the Adviser's
  estimate of such transaction costs, which include the costs of acquiring and
  disposing of Portfolio securities. The transaction fee is not a sales charge
  or load,
 
                                                                     (continued)
    
 
                                       2
<PAGE>
   
  and is retained by the Portfolio. The fee does not apply to portfolios of the
  Fund other than the International Small Cap Portfolio and is not charged in
  connection with the reinvestment of dividends or capital gain distributions.
  The fee will not be charged with respect to purchases and redemptions that do
  not result in actual transaction costs to the Portfolio. Examples of such
  transactions include offsetting purchases and redemptions by different
  shareholders occurring at the same time and in-kind purchases and redemptions.
    
   
<TABLE>
<CAPTION>
                                                                    INTERNATIONAL
                                                  GLOBAL EQUITY        EQUITY         INTERNATIONAL SMALL   ASIAN EQUITY
ANNUAL FUND OPERATING EXPENSES                      PORTFOLIO         PORTFOLIO          CAP PORTFOLIO       PORTFOLIO
- ------------------------------------------------  -------------  -------------------  -------------------  --------------
 (AS A PERCENTAGE OF AVERAGE NET ASSETS)
<S>                                               <C>            <C>                  <C>                  <C>
Management Fee (Net of Fee Waivers)**
  Class A.......................................        0.65%             0.78%                0.87%              0.60%
  Class B.......................................        0.65%             0.78%                  N/A              0.60%
12b-1 Fees
  Class A.......................................         None              None                 None               None
  Class B.......................................        0.25%             0.25%                  N/A              0.25%
Other Expenses
  Class A.......................................        0.35%             0.22%                0.28%              0.40%
  Class B.......................................        0.35%             0.22%                  N/A              0.40%
                                                  -------------         -------              -------       --------------
Total Operating Expenses (Net of Fee Waivers)
  Class A.......................................        1.00%             1.00%                1.15%              1.00%
  Class B.......................................        1.25%             1.25%                  N/A              1.25%
                                                  -------------         -------              -------       --------------
                                                  -------------         -------              -------       --------------
 
<CAPTION>
 
                                                                   EUROPEAN EQUITY      JAPANESE EQUITY    LATIN AMERICAN
ANNUAL FUND OPERATING EXPENSES                                        PORTFOLIO            PORTFOLIO         PORTFOLIO
- ------------------------------------------------                 -------------------  -------------------  --------------
 (AS A PERCENTAGE OF AVERAGE NET ASSETS)
<S>                                               <C>            <C>                  <C>                  <C>
Management Fee (Net of Fee Waivers)**
  Class A......................................................           0.64%                0.73%              0.62%
  Class B......................................................           0.64%                0.73%              0.62%
12b-1 Fees
  Class A......................................................            None                 None               None
  Class B......................................................           0.25%                0.25%              0.25%
Other Expenses
  Class A......................................................           0.36%                0.27%              1.08%
  Class B......................................................           0.36%                0.27%              1.08%
                                                                        -------              -------       --------------
Total Operating Expenses (Net of Fee Waivers)
  Class A......................................................           1.00%                1.00%              1.70%
  Class B......................................................           1.25%                1.25%              1.95%
                                                                        -------              -------       --------------
                                                                        -------              -------       --------------
</TABLE>
    
 
   
 ** The Adviser has agreed to waive its management fees and/or reimburse each
    Portfolio, if necessary, if such fees would cause the total annual operating
    expenses of the Portfolios to exceed a specified percentage of their
    respective average daily net assets. As a result of these reductions, the
    Management Fees stated above are lower than the contractual fees stated
    under "Management of the Fund." The Adviser reserves the right to terminate
    any of its fee waivers and/or expense reimbursements at any time in its sole
    discretion. For further information on Fund expenses, see "Management
    
 
                                       3
<PAGE>
   
    of the Fund." Set forth below, for each Portfolio as applicable, are the
    management fees and total operating expenses absent such fee waivers and/or
    expense reimbursements as a percent of average daily net assets of the Class
    A shares of the Portfolios and Class B Shares of the Multiclass Portfolios,
    respectively.
    
 
   
<TABLE>
<CAPTION>
                                                                                           TOTAL
                                                                                     OPERATING EXPENSES
                                                                                           ABSENT
                                                                  MANAGEMENT            FEE WAIVERS
                                                                FEES ABSENT FEE  --------------------------
PORTFOLIO                                                           WAIVERS        CLASS A       CLASS B
- --------------------------------------------------------------  ---------------  ------------  ------------
<S>                                                             <C>              <C>           <C>
Global Equity.................................................         0.80%           1.15%         1.39%
International Equity..........................................         0.80%           1.02%         1.27%
International Small Cap.......................................         0.95%           1.23%          N/A
Asian Equity..................................................         0.80%           1.25%         1.52%
European Equity...............................................         0.80%           1.16%         1.40%
Japanese Equity...............................................         0.80%           1.07%         1.31%
Latin American................................................         1.10%           2.18%         2.43%
</TABLE>
    
 
   
    The purpose of the table is to assist the investor in understanding the
various expenses that an investor in the Portfolios will bear directly or
indirectly. Expenses and fees are based on actual figures for the fiscal year
ended December 31, 1996. Due to the continuous nature of Rule 12b-1 fees, long
term Class B shareholders may pay more than the equivalent of the maximum
front-end sales charges otherwise permitted by the National Association of
Securities Dealers, Inc. ("NASD") Conduct Rules.
    
 
                                       4
<PAGE>
    The following example illustrates the expenses that you would pay on a
$1,000 investment assuming (1) a 5% rate of return and (2) redemption at the end
of each time period. As noted above, the only fee charged by the Fund upon
purchase or redemption of Fund shares is the 1% transaction fee that may be
assessed on purchases and redemptions of shares of the International Small Cap
Portfolio, which charges are reflected in this example. The example is based on
total operating expenses of the Portfolios after fee waivers.
 
   
<TABLE>
<CAPTION>
                                               3       5       10
                                     1 YEAR  YEARS   YEARS    YEARS
                                     ------  ------  ------  -------
<S>                                  <C>     <C>     <C>     <C>
Global Equity Portfolio
  Class A..........................  $  10   $  32   $  55   $  122
  Class B..........................     13      40      69      151
International Equity Portfolio
  Class A..........................     10      32      55      122
  Class B..........................     13      40      69      151
International Small Cap Portfolio
  Class A..........................     32      57      85      163
Asian Equity Portfolio
  Class A..........................     10      32      55      122
  Class B..........................     13      40      69      151
European Equity Portfolio
  Class A..........................     10      32      55      122
  Class B..........................     13      40      69      151
Japanese Equity Portfolio
  Class A..........................     10      32      55      122
  Class B..........................     13      40      69      151
Latin American Portfolio
  Class A..........................     17      54      92      201
  Class B..........................     20      61     105      227
</TABLE>
    
 
    THIS EXAMPLE SHOULD NOT BE CONSIDERED A REPRESENTATION OF PAST OR FUTURE
EXPENSES OR PERFORMANCE. ACTUAL EXPENSES MAY BE GREATER OR LESS THAN THOSE
SHOWN.
 
                                       5
<PAGE>
                              FINANCIAL HIGHLIGHTS
 
   
    The following tables provide financial highlights for the Class A and Class
B shares of the Multiclass Portfolios and the Class A shares of the
International Small Cap Portfolio for each of the periods presented. The audited
financial highlights for the Portfolios' shares for each of the periods
presented are part of the Fund's financial statements which appear in the Fund's
December 31, 1996 Annual Report to Shareholders and which are incorporated by
reference in the Fund's Statement of Additional Information. The Portfolios'
financial highlights for each of the periods presented have been audited by
Price Waterhouse LLP, whose unqualified report thereon is also incorporated by
reference in the Statement of Additional Information. Additional performance
information is included in the Annual Report. The Annual Report and the
financial statements therein, along with the Statement of Additional
Information, are available at no cost from the Fund at the address and telephone
number noted on the cover page of this Prospectus. After October 31, 1992, the
Fund changed its fiscal year end to December 31. The following information
should be read in conjunction with financial statements and notes thereto.
    
 
                                       6
<PAGE>
                            GLOBAL EQUITY PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                    CLASS A                                             CLASS B
                             --------------------------------------------------------------------------------------   ------------
                                                                                                        PERIOD FROM   PERIOD FROM
                                                                                          TWO MONTHS     JULY 15,      JANUARY 2,
                              YEAR ENDED     YEAR ENDED     YEAR ENDED     YEAR ENDED       ENDED        1992* TO      1996*** TO
                             DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   OCTOBER 31,   DECEMBER 31,
                                 1996           1995           1994           1993           1992          1992           1996
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
<S>                          <C>            <C>            <C>            <C>            <C>            <C>           <C>
NET ASSET VALUE, BEGINNING
 OF PERIOD.................    $ 14.31        $ 13.40        $ 13.87        $  9.75        $  9.35        $ 10.00       $ 14.36
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment Income
   (1).....................       0.23           0.18           0.08           0.08           0.01           0.02          0.13
  Net Realized and
   Unrealized Gain (Loss)
   on Investments..........       3.02           2.26           0.79           4.18           0.39          (0.67)         3.02
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
    Total from Investment
     Operations............       3.25           2.44           0.87           4.26           0.40          (0.65)         3.15
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
DISTRIBUTIONS
  Net Investment Income....      (0.23)         (0.22)         (0.12)         (0.02)            --             --         (0.21)
  In Excess of Net
   Investment Income.......         --             --             --          (0.03)            --             --
  Net Realized Gain........      (1.09)         (1.31)         (1.22)         (0.09)            --             --         (1.09)
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
    Total Distributions....      (1.32)         (1.53)         (1.34)         (0.14)            --             --         (1.30)
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
NET ASSET VALUE, END OF
 PERIOD....................    $ 16.24        $ 14.31        $ 13.40        $ 13.87        $  9.75        $  9.35       $ 16.21
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
TOTAL RETURN...............      22.83%         18.66%          6.95%         44.24%          4.28%         (6.50)%       22.04%
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
RATIOS AND SUPPLEMENTAL
 DATA:
  Net Assets, End of Period
   (Thousands).............    $80,297        $91,675        $78,935        $19,918        $11,739        $11,257        $3,928
  Ratio of Expenses to
   Average Net Assets
   (1).....................       1.00%          1.00%          1.00%          1.00%          1.00%**        1.00%**       1.25%**
  Ratio of Net Investment
   Income to Average Net
   Assets (1)..............       1.38%          1.17%          0.87%          0.84%          0.69%**        1.00%**       1.29%**
  Portfolio Turnover
   Rate....................         26%            28%            12%            42%             5%            10%           26%
  Average Commission Rate
   #.......................    $0.0299            N/A            N/A            N/A            N/A            N/A       $0.0299
</TABLE>
    
 
- ------------------------------
 
   
<TABLE>
<C><S>                                  <C>       <C>       <C>       <C>       <C>         <C>         <C>
(1) Effect of voluntary expense
    limitation during the period:
     Per share benefit to net
      investment income...............   $0.03    $0.02     $0.02     $0.01       $0.02       $0.08       $0.01
   Ratios before expense limitation:
     Expenses to Average Net Assets...    1.15 %   1.13  %   1.24  %   1.66  %     2.49  %**    5.22  %**    1.39  %**
     Net Investment Income (Loss) to
      Average Net Assets..............    1.23 %   1.04  %   0.63  %   0.18  %    (0.80  )%**   (3.22  )%**    1.15  %**
</TABLE>
    
 
   
  * Commencement of operations.
    
 
   
 ** Annualized
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
   
 # Beginning with fiscal year 1996, the Portfolio is required to disclose the
   average commission rate per share it paid for portfolio trades, on which
   commissions were charged, during the period. For the year ended December 31,
   1996, the average commission rate paid on trades on which commissions were
   charged was 0.25% of the trade amount.
    
 
                                       7
<PAGE>
                         INTERNATIONAL EQUITY PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                                                                        CLASS B
                                                                    CLASS A                                           ------------
                             --------------------------------------------------------------------------------------   PERIOD FROM
                                                                                          TWO MONTHS                   JANUARY 2,
                              YEAR ENDED     YEAR ENDED     YEAR ENDED     YEAR ENDED       ENDED       YEAR ENDED     1996*** TO
                             DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   OCTOBER 31,   DECEMBER 31,
                                 1996           1995           1994           1993           1992          1992           1996
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
<S>                          <C>            <C>            <C>            <C>            <C>            <C>           <C>
NET ASSET VALUE, BEGINNING
 OF PERIOD.................  $   15.15      $   15.34      $   14.09      $    9.98      $    9.83      $   10.52     $   15.24
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment Income
   (1).....................       0.25           0.16           0.16           0.15           0.01           0.12          0.23
  Net Realized and
   Unrealized Gain (Loss)
   on Investments..........       2.71           1.55           1.54           4.36           0.14          (0.59)         2.59
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
    Total from Investment
     Operations............       2.96           1.71           1.70           4.51           0.15          (0.47)         2.82
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
DISTRIBUTIONS
  Net Investment Income....      (0.36)         (0.06)         (0.18)         (0.01)            --          (0.17)        (0.33)
  In Excess of Net
   Investment Income.......         --             --             --          (0.13)            --             --            --
  Net Realized Gain........      (0.80)         (1.84)         (0.27)         (0.26)            --          (0.05)        (0.80)
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
    Total Distributions....      (1.16)         (1.90)         (0.45)         (0.40)            --          (0.22)        (1.13)
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
NET ASSET VALUE, END OF
 PERIOD....................  $   16.95      $   15.15      $   15.34      $   14.09      $    9.98      $    9.83     $   16.93
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
TOTAL RETURN...............      19.64%         11.77%         12.39%         46.50%          1.53%         (4.56)%       18.58%
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
                             ------------   ------------   ------------   ------------   ------------   -----------   ------------
RATIOS AND SUPPLEMENTAL
 DATA:
  Net Assets, End of Period
   (Thousands).............  $2,264,424     $1,598,530     $1,304,770     $ 947,045      $ 510,727      $ 486,836     $   5,393
  Ratio of Expenses to
   Average Net
   Assets (1)..............       1.00%          1.00%          1.00%          1.00%          1.00%**        1.00%         1.25%**
  Ratio of Net Investment
   Income to Average Net
   Assets (1)..............       1.64%          1.38%          1.12%          1.25%          0.68%**        1.46%         1.68%**
  Portfolio Turnover
   Rate....................         18%            27%            16%            23%             5%            12%           18%
  Average Commission
   Rate#...................    $0.0238            N/A            N/A            N/A            N/A            N/A       $0.0238
</TABLE>
    
 
- ------------------------
 
   
<TABLE>
<C>  <S>                                  <C>       <C>       <C>       <C>       <C>         <C>       <C>
(1)  Effect of voluntary expense
      limitation during the period:
       Per share benefit to net
        investment
        income..........................   $0.00    $0.003    $0.004     $0.01       $0.00     $0.00      $0.00
     Ratios before expense limitation:
       Expenses to Average Net Assets...    1.02 %    1.03 %    1.03 %    1.06 %      1.14 %**   1.02 %    1.27  %**
       Net Investment Income to Average
        Net Assets......................    1.61 %    1.35 %    1.09 %    1.19 %      0.54 %**   1.44 %    1.66  %**
</TABLE>
    
 
   
 ** Annualized
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
   
 # Beginning with fiscal year 1996, the Portfolio is required to disclose the
   average commission rate per share it paid for portfolio trades, on which
   commissions were charged, during the period. For the year ended December 31,
   1996, the average commission rate paid on trades on which commissions were
   charged was 0.26% of the trade amount.
    
 
                                       8
<PAGE>
                       INTERNATIONAL SMALL CAP PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                                                                PERIOD FROM
                                                                                                               DECEMBER 15,
                                                YEAR ENDED      YEAR ENDED      YEAR ENDED      YEAR ENDED       1992* TO
                                               DECEMBER 31,    DECEMBER 31,    DECEMBER 31,    DECEMBER 31,    DECEMBER 31,
                                                   1996            1995            1994           1993++           1992
                                               -------------   -------------   -------------   -------------   -------------
<S>                                            <C>             <C>             <C>             <C>             <C>
NET ASSET VALUE, BEGINNING OF PERIOD.........  $   14.94       $   15.15       $   14.64       $   10.09       $   10.00
                                               -------------   -------------   -------------   -------------      ------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)..................       0.21            0.24            0.14            0.09            0.01
  Net Realized and Unrealized Gain on
   Investments (2)...........................       2.29            0.15            0.62            4.48            0.08
                                               -------------   -------------   -------------   -------------      ------
    Total from Investment Operations.........       2.50            0.39            0.76            4.57            0.09
                                               -------------   -------------   -------------   -------------      ------
DISTRIBUTIONS
  Net Investment Income......................      (0.22)          (0.23)          (0.03)           0.00              --
  In Excess of Net Investment Income.........         --              --              --           (0.02)             --
  Net Realized Gain..........................      (0.39)          (0.37)          (0.22)             --              --
                                               -------------   -------------   -------------   -------------      ------
    Total Distributions......................      (0.61)          (0.60)          (0.25)          (0.02)             --
                                               -------------   -------------   -------------   -------------      ------
NET ASSET VALUE, END OF PERIOD                 $   16.83       $   14.94       $   15.15       $   14.64       $   10.09
                                               -------------   -------------   -------------   -------------      ------
                                               -------------   -------------   -------------   -------------      ------
TOTAL RETURN.................................      16.82%           2.60%           5.25%          45.34%           0.90%
                                               -------------   -------------   -------------   -------------      ------
                                               -------------   -------------   -------------   -------------      ------
RATIOS AND SUPPLEMENTAL DATA:
  Net Assets, End of Period (Thousands)......  $ 234,743       $ 198,669       $ 160,101       $  52,834       $   3,824
  Ratio of Expenses to Average Net Assets
   (1).......................................       1.15%           1.15%           1.15%           1.15%           1.15%**
  Ratio of Net Investment Income to
   Average Net Assets (1)....................       1.29%           1.72%           1.18%           0.66%           1.37%**
  Portfolio Turnover Rate....................         35%             24%              8%             14%              0%
  Average Commission Rate#...................    $0.0159             N/A             N/A             N/A             N/A
</TABLE>
    
 
- ------------------------------
 
   
<TABLE>
<C> <S>                                        <C>          <C>          <C>          <C>          <C>
(1) Effect of voluntary expense limitation
     during the period:
      Per share benefit to net investment
       income................................     $0.01       $0.01          $0.02        $0.10        $0.16
    Ratios before expense limitation:
      Expenses to Average Net Assets.........      1.23  %      1.24  %       1.29 %       1.86 %      21.67 %**
      Net Investment Income/(Loss) to Average
       Net Assets............................      1.20  %      1.63  %       1.04 %      (0.05 )%    (19.15 )%**
(2) Reflects a 1% transaction fee on
     purchases and redemptions of capital
     shares.
</TABLE>
    
 
   
 * Commencement of operations.
    
 
   
** Annualized
    
 
   
++Per share amounts for the year ended December 31, 1993 are based on average
  outstanding shares.
    
 
   
 #Beginning with fiscal year 1996, the Portfolio is required to disclose the
  average commission rate per share it paid for portfolio trades, on which
  commissions were charged, during the period. For the year ended December 31,
  1996, the average commission rate paid on trades on which commissions were
  charged was 0.30% of the trade amount.
    
 
                                       9
<PAGE>
                             ASIAN EQUITY PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                                                                      CLASS B
                                                                  CLASS A                                           ------------
                           --------------------------------------------------------------------------------------   PERIOD FROM
                                                                                        TWO MONTHS                   JANUARY 2,
                            YEAR ENDED     YEAR ENDED     YEAR ENDED     YEAR ENDED       ENDED       YEAR ENDED     1996*** TO
                           DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   DECEMBER 31,   OCTOBER 31,   DECEMBER 31,
                               1996           1995           1994           1993           1992          1992           1996
                           ------------   ------------   ------------   ------------   ------------   -----------   ------------
<S>                        <C>            <C>            <C>            <C>            <C>            <C>           <C>
NET ASSET VALUE,
 BEGINNING OF PERIOD.....    $ 19.48        $  21.54       $  26.20       $  13.11       $  13.63       $  9.67       $  19.55
                           ------------   ------------   ------------   ------------   ------------   -----------   ------------
INCOME FROM INVESTMENT
 OPERATIONS
  Net Investment Income
   (1)...................       0.17            0.18           0.11           0.10           0.01          0.14           0.11
  Net Realized and
   Unrealized Gain (Loss)
   on Investments........       0.50            1.11          (4.15)         13.38          (0.53)         3.86           0.46
                           ------------   ------------   ------------   ------------   ------------   -----------   ------------
    Total from Investment
     Operations..........       0.67            1.29          (4.04)         13.48          (0.52)         4.00           0.57
                           ------------   ------------   ------------   ------------   ------------   -----------   ------------
DISTRIBUTIONS
  Net Investment
   Income................      (0.15)          (0.34)         (0.09)         (0.01)            --         (0.04)         (0.11)
  In Excess of Net
   Investment Income.....      (0.00)+         (0.00+            --          (0.13)            --            --             --
  Net Realized Gain......      (1.27)          (3.01)         (0.53)         (0.12)            --            --          (1.27)
  In Excess of Net
   Realized Gain.........         --              --             --          (0.13)            --            --
                           ------------   ------------   ------------   ------------   ------------   -----------   ------------
    Total
     Distributions.......      (1.42)          (3.35)         (0.62)         (0.39)            --         (0.04)         (1.38)
                           ------------   ------------   ------------   ------------   ------------   -----------   ------------
NET ASSET VALUE, END OF
 PERIOD..................    $ 18.73        $  19.48       $  21.54       $  26.20       $  13.11       $ 13.63       $  18.74
                           ------------   ------------   ------------   ------------   ------------   -----------   ------------
                           ------------   ------------   ------------   ------------   ------------   -----------   ------------
TOTAL RETURN.............       3.49%           6.87%        (15.81)%       105.71%         (3.82)%       41.50%         2.92%
                           ------------   ------------   ------------   ------------   ------------   -----------   ------------
                           ------------   ------------   ------------   ------------   ------------   -----------   ------------
RATIOS AND SUPPLEMENTAL
 DATA:
  Net Assets, End of
   Period (Thousands)....    $363,498       $314,884       $276,906       $287,136       $ 41,978       $41,017       $ 11,002
  Ratio of Expenses to
   Average Net Assets
   (1)...................       1.00%           1.00%          1.00%          1.00%          1.00%**       1.00%          1.25%**
  Ratio of Net Investment
   Income to Average Net
   Assets (1)............       0.74%           0.97%          0.52%          0.83%          0.61%**       1.53%          0.58%**
  Portfolio Turnover
   Rate..................         69%             42%            47%            18%            10%           33%            69%
  Average Commission
   Rate#.................    $0.0111             N/A            N/A            N/A            N/A           N/A        $0.0111
</TABLE>
    
 
- ------------------------------
 
   
<TABLE>
<C> <S>                                  <C>        <C>        <C>        <C>        <C>        <C>        <C>
(1) Effect of voluntary expense
     limitation during the period:
      Per share benefit to net
       investment income...............   $0.05       $0.03     $0.04      $0.05      $0.02       $0.06     $0.04
    Ratios before expense limitation:
      Expenses to Average Net Assets...    1.25  %    1.18  %    1.20  %    1.38  %    2.02  %**    1.63 %   1.52  %**
      Net Investment Income (Loss) to
       Average Net Assets..............    0.54  %    0.79  %    0.32  %    0.45  %  (0.41)  %**    0.90 %   0.37  %**
</TABLE>
    
 
   
 ** Annualized
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
   
  + Amount is less than $0.01 per share.
    
 
   
 #Beginning with fiscal year 1996, the Portfolio is required to disclose the
  average commission rate per share it paid for portfolio trades, on which
  commissions were charged, during the period. For the year ended December 31,
  1996, the average commission rate paid on trades on which commissions were
  charged was 0.52% of the trade amount.
    
 
                                       10
<PAGE>
                           EUROPEAN EQUITY PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                          CLASS A                                 CLASS B
                                               -------------------------------------------------------------   -------------
                                                                                                PERIOD FROM     PERIOD FROM
                                                                                                 APRIL 2,       JANUARY 2,
                                                YEAR ENDED      YEAR ENDED      YEAR ENDED       1993* TO       1996*** TO
                                               DECEMBER 31,    DECEMBER 31,    DECEMBER 31,    DECEMBER 31,    DECEMBER 31,
                                                   1996            1995            1994            1993            1996
                                               -------------   -------------   -------------   -------------   -------------
<S>                                            <C>             <C>             <C>             <C>             <C>
NET ASSET VALUE, BEGINNING OF PERIOD.........  $   13.92       $   13.94       $   12.91       $   10.00       $   14.05
                                               -------------   -------------   -------------   -------------   -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)..................       0.24            0.14            0.08            0.08            0.18
  Net Realized and Unrealized Gain on
   Investments...............................       2.85            1.37            1.29            2.83            2.73
                                               -------------   -------------   -------------   -------------   -------------
    Total from Investment Operations.........       3.09            1.51            1.37            2.91            2.91
                                               -------------   -------------   -------------   -------------   -------------
DISTRIBUTIONS
  Net Investment Income......................      (0.25)          (0.15)          (0.09)             --           (0.23)
  In Excess of Net Investment Income.........      (0.02)             --              --              --           (0.02)
  Net Realized Gain..........................      (0.04)          (1.38)          (0.25)             --           (0.04)
                                               -------------   -------------   -------------   -------------   -------------
    Total Distributions......................      (0.31)          (1.53)          (0.34)             --           (0.29)
                                               -------------   -------------   -------------   -------------   -------------
NET ASSET VALUE, END OF PERIOD...............  $   16.70       $   13.92       $   13.94       $   12.91       $   16.67
                                               -------------   -------------   -------------   -------------   -------------
                                               -------------   -------------   -------------   -------------   -------------
TOTAL RETURN.................................      22.29%          11.85%          10.88%          29.10%          20.76%
                                               -------------   -------------   -------------   -------------   -------------
                                               -------------   -------------   -------------   -------------   -------------
RATIOS AND SUPPLEMENTAL DATA:
  Net Assets, End of Period (Thousands)......  $ 178,356       $  69,583       $  27,634       $  12,681       $   2,654
  Ratio of Expenses to Average Net Assets
   (1).......................................       1.00%           1.00%           1.00%           1.00%**         1.25%**
  Ratio of Net Investment Income to Average
   Net Assets (1)............................       1.83%           1.37%           0.87%           1.23%**         1.67%**
  Portfolio Turnover Rate....................         24%             13%             79%             15%             24%
  Average Commission Rate#...................    $0.0212             N/A             N/A             N/A         $0.0212
</TABLE>
    
 
- ------------------------
 
   
<TABLE>
<C> <S>                                        <C>        <C>        <C>        <C>        <C>
(1) Effect of voluntary expense limitation
     during the period:
      Per share benefit to net investment
       income................................   $0.02       $0.03     $0.06      $0.09      $0.02
    Ratios before expense limitation:
      Expenses to Average Net Assets.........    1.16  %    1.25  %    1.62  %    2.43  %**   1.40  %**
      Net Investment Income (Loss) to Average
       Net Assets............................    1.67  %    1.12  %    0.25  %   (0.21  )%**   1.52  %**
</TABLE>
    
 
   
  * Commencement of operations.
    
 
   
 ** Annualized
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
   
 # Beginning with fiscal year 1996, the Portfolio is required to disclose the
   average commission rate per share it paid for portfolio trades, on which
   commissions were charged, during the period. For the year ended December 31,
   1996, the average commission rate paid on trades on which commissions were
   charged was 0.23% of the trade amount.
    
 
                                       11
<PAGE>
                           JAPANESE EQUITY PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                  CLASS A                         CLASS B
                                               ---------------------------------------------   -------------
                                                                                PERIOD FROM     PERIOD FROM
                                                                                 APRIL 25,      JANUARY 2,
                                                YEAR ENDED      YEAR ENDED       1994* TO       1996*** TO
                                               DECEMBER 31,    DECEMBER 31,    DECEMBER 31,    DECEMBER 31,
                                                  1996++           1995            1994           1996++
                                               -------------   -------------   -------------   -------------
<S>                                            <C>             <C>             <C>             <C>
NET ASSET VALUE, BEGINNING OF PERIOD.........  $    9.27       $    9.83       $   10.00       $    9.25
                                               -------------   -------------   -------------   -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (Loss) (1)...........         --            0.04           (0.01)          (0.02)
  Net Realized and Unrealized Loss on
   Investments+..............................      (0.13)          (0.40)          (0.16)          (0.14)
                                               -------------   -------------   -------------   -------------
    Total from Investment Operations.........      (0.13)          (0.36)          (0.17)          (0.16)
                                               -------------   -------------   -------------   -------------
DISTRIBUTIONS
  Net Investment Income......................      (0.66)             --              --           (0.64)
  In Excess of Net Investment Income.........      (0.52)          (0.20)             --           (0.51)
                                               -------------   -------------   -------------   -------------
    Total Distributions......................      (1.18)          (0.20)             --           (1.15)
                                               -------------   -------------   -------------   -------------
NET ASSET VALUE, END OF PERIOD...............  $    7.96       $    9.27       $    9.83       $    7.94
                                               -------------   -------------   -------------   -------------
                                               -------------   -------------   -------------   -------------
TOTAL RETURN.................................      (1.40)%         (3.64)%         (1.70)%         (1.67)%
                                               -------------   -------------   -------------   -------------
                                               -------------   -------------   -------------   -------------
RATIOS AND SUPPLEMENTAL DATA:
  Net Assets, End of Period (Thousands)......  $ 152,229       $ 119,278       $  50,332       $   3,431
  Ratio of Expenses to Average Net Assets
   (1).......................................       1.00%           1.00%           1.00%**         1.25%**
  Ratio of Net Investment Income (Loss) to
   Average Net Assets (1)....................      (0.04)%          0.15%          (0.10)%**       (0.26)%**
  Portfolio Turnover Rate....................         38%             52%              1%             38%
  Average Commission Rate#...................    $0.0561             N/A             N/A         $0.0561
</TABLE>
    
 
- ------------------------
 
   
<TABLE>
<C> <S>                                        <C>        <C>        <C>        <C>
(1) Effect of voluntary expense limitation
     during the period:
      Per share benefit to net investment
       income (loss).........................    $0.01      $0.06     $0.02       $0.01
    Ratios before expense limitation:
      Expenses to Average Net Assets.........     1.07 %     1.20 %    1.27  %**    1.31 %**
      Net Investment Income (Loss) to Average
       Net Assets............................    (0.11 )%   (0.05 )%  (0.37  )%**   (0.32 )%**
</TABLE>
    
 
   
  * Commencement of operations.
    
 
   
 ** Annualized
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
   
  + The amount shown for the year ended December 31, 1995 for a share
    outstanding throughout the year does not agree with the amount of aggregate
    net gains on investments for the year because of the timing of sales and
    repurchases of the Portfolio shares in relation to fluctuating market value
    of the investments in the Portfolio.
    
 
   
 ++ Per share amounts for the year ended December 31, 1996 are based on average
    outstanding shares.
    
 
   
 # Beginning with fiscal year 1996, the Portfolio is required to disclose the
   average commission rate per share it paid for portfolio trades, on which
   commissions were charged, during the period. For the year ended December 31,
   1996, the average commission rate paid on trades on which commissions were
   charged was 0.43% of the trade amount.
    
 
                                       12
<PAGE>
                            LATIN AMERICAN PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                CLASS A
                                               -----------------------------------------
                                                                         PERIOD FROM             CLASS B
                                                                         JANUARY 18,       -------------------
                                                   YEAR ENDED         1995* TO DECEMBER    PERIOD FROM JANUARY
                                                  DECEMBER 31,               31,              2, 1996*** TO
                                                      1996                  1995            DECEMBER 31, 1996
                                               -------------------   -------------------   -------------------
<S>                                            <C>                   <C>                   <C>
NET ASSET VALUE, BEGINNING OF PERIOD.........  $          9.06       $         10.00       $          9.44
                                                       -------               -------               -------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)..................             0.14                  0.05                  0.09
  Net Realized and Unrealized Gain (Loss) on
   Investments...............................             4.27                 (0.92)                 3.90
                                                       -------               -------               -------
    Total from Investment Operations.........             4.41                 (0.87)                 3.99
                                                       -------               -------               -------
DISTRIBUTIONS
  Net Investment Income......................            (0.13)                (0.04)                (0.10)
  Net Realized Gain..........................            (2.02)                   --                 (2.02)
  Return of Capital..........................               --                 (0.03)
                                                       -------               -------               -------
    Total Distributions......................            (2.15)                (0.07)                (2.12)
                                                       -------               -------               -------
NET ASSET VALUE, END OF PERIOD...............  $         11.32       $          9.06       $         11.31
                                                       -------               -------               -------
                                                       -------               -------               -------
TOTAL RETURN.................................            48.77%                (8.68)%               42.44%
                                                       -------               -------               -------
                                                       -------               -------               -------
RATIOS AND SUPPLEMENTAL DATA:
  Net Assets, End of Period (Thousands)......  $        30,409       $        15,376       $         1,333
  Ratio of Expenses to Average Net Assets
   (1).......................................             1.70%                 1.70%**               1.95%**
  Ratio of Net Investment Income to Average
   Net Assets (1)............................             1.21%                 0.62%**               0.89%**
  Portfolio Turnover Rate....................              192%                  137%                  192%
  Average Commission Rate#...................          $0.0004                   N/A               $0.0004
</TABLE>
    
 
- ------------------------
 
   
<TABLE>
<C> <S>                                        <C>                <C>                <C>
(1) Effect of voluntary expense limitation
     during the period:
      Per share benefit to net investment
       income................................           $0.05               $0.09          $0.05
    Ratios before expense limitation:
      Expenses to Average Net Assets.........            2.18  %            3.13  %**        2.43     %**
      Net Investment Loss to Average Net
       Assets................................            0.75  %           (0.48  )%**        0.42     %**
</TABLE>
    
 
   
  * Commencement of Operations.
    
 
   
 ** Annualized
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
   
 # Beginning with fiscal year 1996, the Portfolio is required to disclose the
   average commission rate per share it paid for portfolio trades, on which
   commissions were charged, during the period. For the year ended December 31,
   1996, the average commission rate paid on trades on which commissions were
   charged was 0.30% of the trade amount.
    
 
                                       13
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
 
    The Fund consists of twenty-nine portfolios, offering institutional
investors and high net worth individual investors a broad range of investment
choices coupled with the advantages of a no-load mutual fund with Morgan Stanley
and its affiliates providing customized services as Adviser, Administrator and
Distributor. Each portfolio offers Class A shares and, except for the
International Small Cap, Money Market and Municipal Money Market Portfolios,
also offers Class B shares. Each portfolio has its own investment objective and
policies designed to meet its specific goals. The investment objective of each
Portfolio described in this Prospectus is as follows:
 
    -The GLOBAL EQUITY PORTFOLIO seeks long-term capital appreciation by
     investing primarily in equity securities of issuers throughout the world,
     including U.S. issuers.
 
    -The INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation by
     investing primarily in equity securities of non-U.S. issuers.
 
    -The INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital appreciation
     by investing primarily in equity securities of non-U.S. issuers with equity
     market capitalizations of less than $1 billion.
 
    -The ASIAN EQUITY PORTFOLIO seeks long-term capital appreciation by
     investing primarily in equity securities of Asian issuers.
 
    -The EUROPEAN EQUITY PORTFOLIO seeks long-term capital appreciation by
     investing primarily in equity securities of European issuers.
 
    -The JAPANESE EQUITY PORTFOLIO seeks long-term capital appreciation by
     investing primarily in equity securities of Japanese issuers.
 
   
    -The LATIN AMERICAN PORTFOLIO seeks long-term capital appreciation by
     investing primarily in equity securities of Latin American issuers and,
     from time to time, debt securities issued or guaranteed by Latin American
     governments or governmental entities.
    
 
    The other portfolios of the Fund are described in other prospectuses which
may be obtained from the Fund at the address and phone number noted on the cover
page of this Prospectus. The investment objectives of these other portfolios are
listed below:
 
    GLOBAL AND INTERNATIONAL EQUITY:
 
    -The ACTIVE COUNTRY ALLOCATION PORTFOLIO seeks long-term capital
     appreciation by investing in accordance with country weightings determined
     by the Adviser in equity securities of non-U.S. issuers which, in the
     aggregate, replicate broad country indices.
 
    -The CHINA GROWTH PORTFOLIO seeks to provide long-term capital appreciation
     by investing primarily in equity securities of issuers in The People's
     Republic of China, Hong Kong and Taiwan.
 
    -The EMERGING MARKETS PORTFOLIO seeks long-term capital appreciation by
     investing primarily in equity securities of emerging country issuers.
 
    -The INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation by
     investing primarily in equity securities of non-U.S. issuers domiciled in
     EAFE countries.
 
                                       14
<PAGE>
    -The GOLD PORTFOLIO seeks long-term capital appreciation by investing
     primarily in equity securities of foreign and domestic issuers engaged in
     gold-related activities.
 
    U.S. EQUITY:
 
    -The AGGRESSIVE EQUITY PORTFOLIO seeks capital appreciation by investing
     primarily in corporate equity and equity-linked securities.
 
    -The EMERGING GROWTH PORTFOLIO seeks long-term capital appreciation by
     investing primarily in growth-oriented equity securities of small- to
     medium-sized corporations.
 
    -The EQUITY GROWTH PORTFOLIO seeks long-term capital appreciation by
     investing in growth-oriented equity securities of medium and large
     capitalization companies.
 
    -The MICROCAP PORTFOLIO seeks long-term capital appreciation by investing
     primarily in growth-oriented equity securities of small corporations.
 
    -The SMALL CAP VALUE EQUITY PORTFOLIO seeks high long-term total return by
     investing in undervalued equity securities of small- to medium-sized
     companies.
 
    -The TECHNOLOGY PORTFOLIO seeks long-term capital appreciation by investing
     primarily in equity securities of companies that, in the opinion of the
     Portfolio's investment adviser, are expected to benefit from their
     involvement in technology and technology-related industries.
 
    -The U.S. REAL ESTATE PORTFOLIO seeks to provide above average current
     income and long-term capital appreciation by investing primarily in equity
     securities of companies in the U.S. real estate industry, including real
     estate investment trusts.
 
    -The VALUE EQUITY PORTFOLIO seeks high total return by investing in equity
     securities which the Adviser believes to be undervalued relative to the
     stock market in general at the time of purchase.
 
    EQUITY AND FIXED INCOME:
 
    -The BALANCED PORTFOLIO seeks high total return while preserving capital by
     investing in a combination of undervalued equity securities and fixed
     income securities.
 
    FIXED INCOME:
 
    -The EMERGING MARKETS DEBT PORTFOLIO seeks high total return by investing
     primarily in debt securities of government, government-related and
     corporate issuers located in emerging countries.
 
    -The FIXED INCOME PORTFOLIO seeks to produce a high total return consistent
     with the preservation of capital by investing in a diversified portfolio of
     fixed income securities.
 
    -The GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real rate
     of return while preserving capital by investing in fixed income securities
     of issuers throughout the world, including U.S. issuers.
 
    -The HIGH YIELD PORTFOLIO seeks to maximize total return by investing in a
     diversified portfolio of high yield fixed income securities that offer a
     yield above that generally available on debt securities in the three
     highest rating categories of the recognized rating services.
 
    -The MORTGAGE-BACKED SECURITIES PORTFOLIO seeks to produce as high a level
     of current income as is consistent with the preservation of capital by
     investing primarily in a variety of investment-grade mortgage-backed
     securities.
 
                                       15
<PAGE>
    -The MUNICIPAL BOND PORTFOLIO seeks to produce a high level of current
     income consistent with preservation of principal by investing primarily in
     municipal obligations, the interest on which is exempt from federal income
     tax.
 
    MONEY MARKET:
 
    -The MONEY MARKET PORTFOLIO seeks to maximize current income and preserve
     capital while maintaining high levels of liquidity through investing in
     high-quality money market instruments with remaining maturities of one year
     or less.
 
    -
    The MUNICIPAL MONEY MARKET PORTFOLIO seeks to maximize current tax-exempt
    income and preserve capital while maintaining high levels of liquidity
    through investing in high-quality money market instruments with remaining
    maturities of one year or less which are exempt from federal income tax.
 
    THE CHINA GROWTH, MICROCAP AND MORTGAGE-BACKED SECURITIES PORTFOLIOS ARE
    CURRENTLY NOT BEING OFFERED.
 
INVESTMENT MANAGEMENT
 
   
    Morgan Stanley Asset Management Inc., a wholly owned subsidiary of Morgan
Stanley Group Inc., which, together with its affiliated asset management
companies, at March 31, 1997 had in excess of $118 billion in assets under
management as an investment manager or as a fiduciary adviser, acts as
investment adviser to the Fund and each of its portfolios. See "Management of
the Fund -- Investment Adviser" and "Management of the Fund -- Administrator."
    
 
HOW TO INVEST
 
    Class A shares of each Portfolio are offered directly to investors at net
asset value with no sales commission or 12b-1 charges. Class B shares of each
Multiclass Portfolio are offered at net asset value with no sales commission,
but with a 12b-1 fee, which is accrued daily and paid quarterly, equal to 0.25%
of the Class B shares' average daily net assets on an annualized basis.
Shareholders of the International Small Cap Portfolio may be charged a 1.00%
transaction fee, which is payable directly to the International Small Cap
Portfolio, in connection with each purchase and redemption of shares of the
Portfolio. Share purchases may be made by sending investments directly to the
Fund or through the Distributor. The minimum initial investment, generally, is
$500,000 for Class A shares of each Portfolio and $100,000 for Class B shares of
each Multiclass Portfolio. The minimum initial investment amount is reduced for
certain categories of investors. For additional information on how to purchase
shares and minimum initial investments, see "Purchase of Shares."
 
                                       16
<PAGE>
HOW TO REDEEM
 
    Shares of each Portfolio may be redeemed at any time, without cost, at the
net asset value per share of shares of the applicable class next determined
after receipt of the redemption request, (except that shareholders of the
International Small Cap Portfolio may be charged a 1.00% transaction fee, which
is payable directly to the International Small Cap Portfolio, in connection with
each purchase and redemption of shares of the Portfolio). The redemption price
may be more or less than the purchase price. Certain redemptions that cause the
value of an account to remain for a continuous 60-day period below the minimum
investment amount for Class A shares or for Class B shares may result in
involuntary redemption or automatic conversion. For additional information on
how to redeem shares and involuntary redemption or conversion, see "Purchase of
Shares -- Minimum Account Sizes and Involuntary Redemption of Shares" and
"Redemption of Shares."
 
RISK FACTORS
 
   
    The investment policies of each of the Portfolios entail certain risks and
considerations of which an investor should be aware. Each Portfolio will invest
in securities of foreign issuers, which are subject to certain risks not
typically associated with domestic securities. Each Portfolio may invest in
securities of issuers located in emerging markets. These securities may impose
greater liquidity risks and other risks not typically associated with investing
in more established markets. The Latin American Portfolio may invest up to 20%
of its total assets in lower rated debt securities ("junk bonds"), which are
considered speculative with regard to the payment of interest and return of
principal. See "Investment Objectives and Policies" and "Additional Investment
Information." In addition, each Portfolio may invest in repurchase agreements,
lend its portfolio securities, purchase securities on a when-issued or delayed
delivery basis and invest in foreign currency forward contracts. The Latin
American Portfolio may invest in foreign currency exchange futures and options
to hedge currency risk associated with investment in non-U.S. dollar denominated
securities and may also invest in futures contracts and options on futures
contracts with respect to securities and indices. The Latin American Portfolio
may invest in certain derivatives, including options, futures and options on
futures. These investments entail certain costs and risks, including imperfect
correlation between the value of securities held by the Portfolio and the value
of the particular derivative instrument, and the risk that the Portfolio could
not close out a derivatives position when it would be most advantageous to do
so. The Asian Equity, International Small Cap and Latin American Portfolios may
invest in securities that are neither listed on a stock exchange nor traded
over-the-counter, including private placement securities. The Global Equity,
Japanese Equity, Latin American and Asian Equity Portfolios may also invest
indirectly in securities through sponsored or unsponsored Depositary Receipts.
Because the Latin American Portfolio is a non-diversified portfolio, the
Portfolio will invest a greater proportion of its assets in the securities of a
smaller number of issuers and, as a result, will be subject to greater risk with
respect to its portfolio securities. Each of these investment strategies
involves specific risks which are described under "Investment Objectives and
Policies" and "Additional Investment Information" herein and under "Investment
Objectives and Policies" in the Statement of Additional Information.
    
 
                                       17
<PAGE>
                       INVESTMENT OBJECTIVES AND POLICIES
 
    The investment objective of each Portfolio is described below, together with
the policies the Portfolios employ in their efforts to achieve these objectives.
Each Portfolio's investment objective is a fundamental policy which may not be
changed without the approval of a majority of the Portfolio's outstanding voting
securities. There is no assurance that the Portfolios will attain their
objectives. Each of the Portfolios invests in equity securities, which include
common and preferred stocks, convertible securities, rights and warrants to
purchase common stocks and, in the case of the Latin American Portfolio, equity
interests in trusts and partnerships. In addition to the investments and
strategies described below, the Portfolios may invest in certain securities and
obligations as set forth in "Additional Investment Information" below. The
investment policies described below are not fundamental policies and may be
changed without shareholder approval.
 
THE GLOBAL EQUITY PORTFOLIO
 
   
    The Global Equity Portfolio seeks long-term capital appreciation by
investing primarily in equity securities of issuers throughout the world,
including U.S. issuers. At least 65% of the total assets of the Portfolio will
be invested in equity securities under normal circumstances. The Adviser expects
that, under normal circumstances, at least 20% of the Portfolio's total assets
will be invested in the common stocks of U.S. issuers. The remainder of the
Portfolio will be invested in issuers located throughout the world, including
those located in emerging markets. Securities of issuers located in emerging
markets may not be as liquid as those in developed markets and pose greater
risks. Although the Portfolio intends to invest primarily in securities listed
on stock exchanges, it will also invest in securities traded in over-the-counter
markets and may invest in equity securities in the form of Depositary Receipts.
    
 
    The Adviser's approach in selecting investments for the Portfolio is
oriented to individual stock selection, and is value driven. In selecting stocks
for the Portfolio, the Adviser initially identifies those stocks which it
believes to be undervalued in relation to the issuer's assets, cash flow,
earnings and revenues, and then evaluates the future value of such stocks by
running the results of an in-depth study of the issuer through a dividend
discount model. The Adviser utilizes the research of a number of sources,
including Morgan Stanley Capital International, an affiliate of the Adviser
located in Geneva, Switzerland, in identifying attractive securities, and
applies a number of proprietary screening criteria to identify those securities
it believes to be undervalued. Portfolio holdings are regularly reviewed and
subjected to fundamental analysis to determine whether they continue to conform
to the Adviser's value criteria. Securities which no longer conform to such
value criteria are sold.
 
THE INTERNATIONAL EQUITY PORTFOLIO
 
    The investment objective of the International Equity Portfolio is to provide
long-term capital appreciation. The production of any current income is
incidental to this objective. The Portfolio seeks to achieve its objective by
investing primarily in equity securities of non-U.S. issuers. At least 65% of
the total assets of the Portfolio will be invested in such equity securities
under normal circumstances.
 
    The Adviser's orientation to individual stock selection and value driven
approach in selecting investments for the Portfolio are the same as those
described for the Global Equity Portfolio discussed above. While the Portfolio
is not subject to any specific geographic diversification requirements, it
currently intends to diversify investments among countries to reduce risk,
including currency risk. Investments will be made primarily in equity securities
of companies domiciled in developed countries, but may also be made in equity
securities of
 
                                       18
<PAGE>
issuers domiciled in emerging markets. The Portfolio will not, under normal
circumstances, invest in equity securities of U.S. issuers. Although the
Portfolio intends to invest primarily in equity securities listed on stock
exchanges, it will also invest in equity securities traded in over-the-counter
markets. Securities of companies in emerging countries may pose liquidity risks.
For a description of special considerations and certain risks associated with
investments in foreign issuers, see "Additional Investment Information."
 
THE INTERNATIONAL SMALL CAP PORTFOLIO
 
    The investment objective of the International Small Cap Portfolio is to
provide long-term capital appreciation. The production of any current income is
incidental to this objective. The Portfolio seeks to achieve its objective by
investing primarily in equity securities of non-U.S. issuers with equity market
capitalizations of less than $1 billion. At least 65% of the total assets of the
Portfolio will be invested in such equity securities under normal circumstances.
The Portfolio will invest a minimum of 80% of its total assets in companies with
market capitalizations of less than $1 billion. The Adviser's orientation to
individual stock selection and value driven approach in selecting investments
for the Portfolio are the same as those described for the Global Equity
Portfolio discussed above.
 
    While the Portfolio is not subject to any specific geographic
diversification requirements, it currently intends to diversify investments
among countries to reduce risk, including currency risk. Investments will be
made primarily in equity securities of companies domiciled in developed
countries. Limited investments may also be made in the securities of companies
domiciled in emerging countries, but will not normally exceed 5% of the total
assets of the Portfolio. Although the Portfolio intends to invest primarily in
equity securities listed on stock exchanges, it may also invest in equity
securities traded in over-the-counter markets and in privately placed
securities. Small capitalization securities involve greater issuer risk and the
markets for such securities may be more volatile and less liquid. Securities of
companies in emerging countries may pose liquidity risks. The Portfolio will
not, under normal circumstances, invest in equity securities of U.S. issuers.
For a description of special considerations and certain risks associated with
investments in foreign issuers, see "Additional Investment Information."
 
THE ASIAN EQUITY PORTFOLIO
 
    The investment objective of the Asian Equity Portfolio is to provide
long-term capital appreciation. The production of any current income is
incidental to this objective. The Portfolio seeks to achieve its objective by
investing primarily in equity securities which are traded on recognized stock
exchanges of the countries in Asia described below and in equity securities of
companies organized under the laws of an Asian country whose business is
conducted principally in Asia. The Portfolio does not intend to invest in equity
securities which are principally traded in markets in Japan or in companies
organized under the laws of Japan. The Portfolio may also invest in Depositary
Receipts of Asian issuers.
 
    The Portfolio will invest primarily in the more established Asian markets,
including Hong Kong, Singapore, Malaysia, Thailand, the Philippines and
Indonesia. The Portfolio may also invest in common stocks traded on markets in
Taiwan, South Korea, India, Pakistan, Sri Lanka and other emerging markets that
are open to foreign investment. There is no requirement that the Portfolio, at
any given time, invest in any or all of the countries listed above or in any
other Asian countries. The Portfolio has no set policy for allocating
investments among the
 
                                       19
<PAGE>
various Asian countries. Allocation of investments will depend on the relative
attractiveness of the stocks of issuers in the respective countries. Government
regulation and restrictions in many of the countries of interest may limit the
amount, mode and extent of investment in companies of such countries.
 
    At least 65% of the total assets of the Portfolio will be invested in common
stocks of Asian countries under normal circumstances. The remaining portion of
the Portfolio will be kept in any combination of debt instruments, bills and
bonds of governmental entities in Asia and the United States, in notes,
debentures and bonds of companies in Asia and in money market instruments.
 
   
    The Adviser's orientation to individual stock selection and value driven
approach in selecting investments for the Portfolio are similar to those
described for the Global Equity Portfolio discussed above. The Adviser will
analyze assets, revenues and earnings of an issuer. In selecting industries and
particular issuers, the Adviser will evaluate costs of labor and raw materials,
access to technology, export of products and government regulation. Although the
Portfolio seeks to invest in larger companies, it may invest in medium-sized and
small companies that, in the Adviser's view, have potential for growth.
    
 
    The Portfolio's investments will include securities of issuers located in
emerging countries and traded in emerging markets. These securities pose greater
liquidity risks and other risks than securities of companies located in
developed countries and traded in more established markets. For a description of
special considerations and certain risks associated with investment in foreign
issuers, see "Additional Investment Information."
 
    Although the Portfolio intends to invest primarily in equity securities
listed on stock exchanges, it will also invest in equity securities traded in
over-the-counter markets and in Depositary Receipts. Securities traded in
over-the-counter markets pose liquidity risks. Pending investment or settlement,
and for liquidity purposes, the Portfolio may invest in domestic, Eurodollar and
foreign short-term money market instruments. The Portfolio may also invest in
initial public offerings in the form of oversubscriptions or private placements.
Such investments generally entail short-term liquidity risks.
 
    The Portfolio may enter into currency exchange contracts. Because of the
lack of hedging facilities in the currency markets of Asia, the Portfolio
currently does not actively engage in currency hedging strategies, although it
may do so in the future. Instead, each investment will be considered on a total
currency adjusted basis with the U.S. dollar as a base currency. See "Foreign
Currency Forward Contracts."
 
THE EUROPEAN EQUITY PORTFOLIO
 
    The investment objective of the European Equity Portfolio is to provide
long-term capital appreciation. The Portfolio seeks to achieve this objective by
investing primarily in equity securities of European issuers, including those
located in Germany, France, Switzerland, Belgium, Italy, Finland, Sweden,
Denmark, Norway and the United Kingdom. Investments may also be made in equity
securities of issuers located in the smaller and emerging markets of Europe.
 
    While the Portfolio is not subject to any specific geographic
diversification requirements, it currently intends to diversify investments
among countries to reduce currency risk. At least 65% of the total assets of the
Portfolio will be invested in equity securities of European issuers under normal
circumstances. The Portfolio will not, under normal circumstances, invest in
equity securities of U.S. issuers. The Adviser's orientation to individual stock
selection and value-driven approach in selecting investments for the Portfolio
are the same as those described for the Global Equity Portfolio discussed above.
Securities in emerging markets may not be as
 
                                       20
<PAGE>
liquid as those in developed markets and pose greater risks. Although the
Portfolio intends to invest primarily in equity securities listed on stock
exchanges, it will also invest in equity securities traded in over-the-counter
markets. For a description of special considerations and certain risks
associated with investments in foreign issuers, see "Additional Investment
Information."
 
THE JAPANESE EQUITY PORTFOLIO
 
    The investment objective of the Japanese Equity Portfolio is to provide
long-term capital appreciation. The Portfolio seeks to achieve this objective by
investing primarily in equity securities of Japanese issuers. Under normal
conditions, the Portfolio will invest at least 80% of its total assets in
securities of issuers that are organized under the laws of Japan, affiliates of
Japanese companies (wherever organized or traded) and issuers not organized
under the laws of Japan but deriving 50% or more of their revenues from Japan.
These securities may include debt securities (issued by the Japanese government
or by Japanese companies) when the Adviser believes that the potential for
capital appreciation from investment in debt securities equals or exceeds that
available from investment in equity securities. All debt securities in which the
Portfolio may invest will be rated no lower than BBB by Standard & Poor's
Ratings Group ("S&P"), Baa by Moody's Investors Service, Inc. ("Moody's") or BBB
by Mikuni Inc. ("Mikuni") (a Japanese rating agency) or, if unrated, of
comparable quality as determined by the Adviser. Securities rated BBB by S&P,
Baa by Moody's or BBB by Mikuni have speculative characteristics and changes in
economic conditions or other circumstances are more likely to lead to a weakened
capacity to make principal and interest payments on such securities than would
be the case with higher rated securities. The convertible securities in which
the Portfolio may invest include bonds, notes, debentures, preferred stocks and
other securities convertible into common stocks and may be fixed-income or zero
coupon debt securities. Prior to their conversion, convertible securities may
have characteristics similar to nonconvertible debt securities.
 
    The Portfolio currently intends to focus its investments in Japanese
companies that have an active market for their shares and that the Adviser
believes show a potential for better than average growth. In making investment
decisions, the Adviser will consider, among other factors, the size of the
company, its financial condition, its marketing and technical strengths and its
competitiveness in its industry. The Portfolio anticipates that most equity
securities of Japanese companies in which it invests, either directly or
indirectly by means of Depositary Receipts or convertible debentures, will be
listed on securities exchanges in Japan. The Portfolio may also invest in equity
securities of Japanese companies that are traded in an over-the-counter market.
 
    RISK FACTORS RELATING TO JAPANESE EQUITY PORTFOLIO.  Investors should
consider the following factors inherent in investment in Japan.
 
    TRADE ISSUES.  Because of the concentration of Japanese exports in highly
visible products such as automobiles, machine tools and semiconductors, and the
large trade surpluses ensuing therefrom, Japan is in a difficult phase in its
relation with its trading partners, particularly the United States, where the
trade imbalance is the greatest. Retaliatory action taken by such trading
partners could affect the ability of Japanese companies to export goods to these
countries, which could negatively impact the value of securities in the
Portfolio.
 
    CURRENCY FACTORS.  Over time, the yen has generally appreciated in relation
to the U.S. dollar. The yen's appreciation would add to the returns of dollars
invested through the Portfolio in Japan. A decline in the value of the yen would
have the opposite effect, adversely affecting the value of the Portfolio in U.S.
dollar terms.
 
                                       21
<PAGE>
    THE JAPANESE STOCK MARKET.  Like other stock markets, the Japanese stock
market can be volatile. A decline in the market may have an adverse effect on
the availability of credit and on the value of the substantial stock holdings of
Japanese companies, in particular, Japanese banks, insurance companies and other
financial institutions. A decline in the market may contribute to weakness in
Japan's economy. The common stocks of many Japanese companies continue to trade
at high price-earnings ratios even after the recent market decline. Differences
in accounting methods make it difficult to compare the earnings of Japanese
companies with those of companies in other countries, especially the United
States. In general, however, reported net income in Japan is understated
relative to U.S. accounting standards. In addition, Japanese companies have
tended historically to have higher growth rates than U.S. companies, and
Japanese interest rates have generally been lower than in the United States,
both of which factors tend to result in lower discount rates and higher
price-earnings ratios in Japan than in the United States.
 
THE LATIN AMERICAN PORTFOLIO
 
    The investment objective of the Latin American Portfolio is long-term
capital appreciation. The Portfolio seeks to achieve this objective by investing
primarily in equity securities (i) of companies organized in or for which the
principal securities trading market is in Latin America, (ii) denominated in a
Latin American currency and issued by companies to finance operations in Latin
America, or (iii) of companies that alone or on a consolidated basis derive 50%
or more of their annual revenues from either goods produced, sales made or
services performed in Latin America (collectively, "Latin American issuers") and
by investing, from time to time, in debt securities issued or guaranteed by a
Latin American government or governmental entity. Under normal conditions,
substantially all, but not less than 80%, of the Portfolio's total assets are
invested in equity securities of Latin American issuers and in debt securities
issued or guaranteed by a Latin American government or governmental entity. For
purposes of this Prospectus, unless otherwise indicated, Latin America consists
of Argentina, Bolivia, Brazil, Chile, Colombia, Costa Rica, Cuba, the Dominican
Republic, Ecuador, El Salvador, Guatemala, Honduras, Mexico, Nicaragua, Panama,
Paraguay, Peru, Uruguay and Venezuela.
 
    The Portfolio focuses its investments in listed equity securities in
Argentina, Brazil, Chile and Mexico, the most developed capital markets in Latin
America. The Portfolio expects, under normal market conditions, to have at least
55% of its total assets invested in listed equity securities of issuers in these
four countries. The Portfolio is not limited in the extent to which it may
invest in any Latin American country and intends to invest opportunistically as
markets develop. The portion of the Portfolio's holdings in any Latin American
country will vary from time to time, although the portion of the Portfolio's
assets invested in Chile may tend to vary less than the portions invested in
other Latin American countries because, with limited exceptions, capital
invested in Chile currently cannot be repatriated for one year. Equity
securities in which the Portfolio may invest include those that are neither
listed on a stock exchange nor traded over-the-counter. As a result of the
absence of a public trading market for these securities, they may be less liquid
than publicly traded securities.
 
    The governments of some Latin American countries have been engaged in
programs of selling part or all of their stakes in government owned or
controlled enterprises ("privatizations"). The Adviser believes that
privatizations may offer investors opportunities for significant capital
appreciation and intends to invest assets of the Portfolio in privatizations in
appropriate circumstances. In certain Latin American countries, the ability of
foreign entities, such as the Portfolio, to participate in privatizations may be
limited by local law, or the terms on
 
                                       22
<PAGE>
which the Portfolio may be permitted to participate may be less advantageous
than those for local investors. There can be no assurance that Latin American
governments will continue to sell companies currently owned or controlled by
them or that any privatization programs in which the Portfolio participates will
be successful.
 
    The Portfolio may participate in debt to equity conversion programs adopted
by several Latin American countries, pursuant to which investors may use
government issued or guaranteed debt securities, directly or indirectly, to make
investments in local companies. The terms of the various programs vary from
country to country although each program includes significant restrictions on
the application of the proceeds received in the conversion and on the remittance
of profits on the investment and of the invested capital. The Adviser will
evaluate opportunities to enter into debt to equity conversion transactions as
they arise.
 
   
    The Portfolio's holdings may consist of lower-quality debt securities, many
of which trade at substantial discounts from face value, and may include
securities rated as low as D by S&P or C by Moody's. The issuers or governmental
authorities that control the repayment of the debt securities held by the
Portfolio may be unable or unwilling to repay the principal and/or interest when
due in accordance with the terms of such debt. Additionally, the willingness or
ability of many Latin American government or government related issuers to repay
principal and interest due in a timely manner may be affected by, among other
factors, its cash flow situation, the extent of its foreign reserves, the
availability of sufficient foreign exchange on the date a payment is due, the
relative size of the debt service burden to the economy as a whole, the
sovereign debtor's policy towards the International Monetary Fund (the "IMF")
and the political constraints to which a sovereign debtor may be subject.
Issuers may also be dependent on expected disbursements from foreign
governments, multilateral agencies and others abroad to reduce principal and
interest arrearages on their debt. These disbursements may be conditioned on the
issuer's implementation of economic reforms and/or economic performance and the
timely service of such debtor's obligations. Failure to satisfy these conditions
may result in the cancellation of such third parties' commitments to lend funds
to the sovereign debtor, which may further impair such debtor's ability or
willingness to timely service its debts. In certain instances, the Portfolio may
invest in government issued or guaranteed debt that is in default as to payments
of principal and/or interest. To the extent the Portfolio is holding government
issued or guaranteed debt, it may incur additional expenses in connection with
any restructuring of the issuer's obligations or in otherwise enforcing its
rights. Investment in such debt securities involves a high degree of risk and is
generally considered to be speculative. The Portfolio will invest in such debt
securities only when the Portfolio believes such investments offer opportunities
for long-term capital appreciation.
    
 
    To the extent that the Portfolio's assets are not invested in equity
securities of Latin American issuers or in government issued or guaranteed debt
securities, the remainder of its assets may be invested in (i) debt securities
of other Latin American issuers, (ii) equity or debt securities of corporate or
governmental issuers located in countries outside Latin America, and (iii)
short-term and medium-term debt securities of the type described under
"Additional Investment Information -- Temporary Investments" below. The
Portfolio's assets may be invested in debt securities when the Portfolio
believes that, based upon factors such as relative interest rate levels and
foreign exchange rates, debt securities offer opportunities for long-term
capital appreciation. It is likely that many of the debt securities in which the
Portfolio will invest will be unrated. The Portfolio may invest up to 20% of its
total assets in lower-quality debt securities that are determined by the Adviser
to be comparable
 
                                       23
<PAGE>
to securities rated below investment grade by S&P or Moody's ("junk bonds").
Investment in such debt securities involves a high degree of risk and is
generally considered to be speculative in nature. See "Additional Investment
Information -- Lower Rated Debt Securities."
 
   
    The Portfolio will not invest more than 25% of its total assets in one
industry except and to the extent, and only for such period of time as, the
Board of Directors determines in view of the considerations discussed below that
it is appropriate and in the best interest of the Portfolio and its shareholders
to invest more than 25% of the Portfolio's total assets in companies involved in
the telecommunications industry or financial services industry, respectively.
Since the securities markets of Latin American countries are emerging markets
characterized by a relatively small number of issues, it is possible that one or
more markets may on occasion be dominated by issues of companies engaged in
these two industries. In addition, it is possible that government privatizations
in certain Latin American countries, which currently represent a primary source
of new issues in many Latin American markets and often represent attractive
investment opportunities, will occur in these two industries. If the Board of
Directors permits greater than 25% of the Portfolio's total assets to be
invested in the telecommunications or financial services industry, the Portfolio
may be exposed to increased investment risks peculiar to that industry. The
Portfolio will notify its shareholders of any decision by the Board of Directors
to permit (or cease) investments of more than 25% of the Portfolio's total
assets in the telecommunications or financial services industry including, if
applicable, a discussion of any increased investment risks peculiar to such
industry to which the Portfolio may be exposed.
    
 
                       ADDITIONAL INVESTMENT INFORMATION
 
    BORROWING AND OTHER FORMS OF LEVERAGE.  The Latin American Portfolio is
authorized to borrow money from banks and other entities in an amount up to
33 1/3% of its total assets (including the amount borrowed) less all liabilities
and indebtedness other than the borrowing, and may use the proceeds of the
borrowing for investment purposes or to pay dividends. Borrowing for investment
purposes creates leverage which is a speculative characteristic. Although the
Portfolio is authorized to borrow, it will do so only when the Adviser believes
that borrowing will benefit the Portfolio after taking into account
considerations such as the costs of borrowing and the likely investment returns
on securities purchased with borrowed monies. Borrowing by the Portfolio will
create the opportunity for increased net income but, at the same time, will
involve special risk considerations. Leverage that results from borrowing will
magnify declines as well as increases in the Portfolio's net asset value per
share and net yield.
 
    The Portfolio expects that all of its borrowing will be made on a secured
basis. The Portfolio's Custodian will either segregate the assets securing the
borrowing for the benefit of the lenders or arrangements will be made with a
suitable sub-custodian. If assets used to secure the borrowing decrease in
value, the Portfolio may be required to pledge additional collateral to the
lender in the form of cash or securities to avoid liquidation of those assets.
 
    DEPOSITARY RECEIPTS.  The Asian Equity, Global Equity, Latin American and
Japanese Equity Portfolios may invest in Depositary Receipts, including American
Depositary Receipts ("ADRs"), Global Depositary Receipts ("GDRs"), European
Depositary Receipts ("EDRs") and other Depositary Receipts (which, together with
ADRs, GDRs and EDRs, are hereinafter collectively referred to as "Depositary
Receipts"), to the extent that such Depositary Receipts are or become available.
ADRs are securities, typically issued by a U.S. financial
 
                                       24
<PAGE>
   
institution (a "depositary"), that evidence ownership interests in a security or
a pool of securities issued by a foreign issuer (the "underlying issuer") and
deposited with the depositary. ADRs include American Depositary Shares and New
York Shares and may be "sponsored" or "unsponsored." Sponsored ADRs are
established jointly by a depositary and the underlying issuer, whereas
unsponsored ADRs may be established by a depositary without participation by the
underlying issuer. The issuers of the stock of unsponsored ADRs are not
obligated to disclose material information in the United States and therefore,
there may not be a correlation between such information and the market value of
the ADR. GDRs, EDRs and other types of Depositary Receipts are typically issued
by foreign depositaries, although they may also be issued by U.S. depositaries,
and evidence ownership interests in a security or pool of securities issued by
either a foreign or a U.S. corporation. Generally, Depositary Receipts in
registered form are designed for use in the U.S. securities market and
Depositary Receipts in bearer form are designed for use in securities markets
outside the United States. The Portfolios may invest in sponsored and
unsponsored Depositary Receipts. For purposes of the Portfolios' investment
policies, the Portfolios' investments in Depositary Receipts will be deemed to
be investments in the underlying securities.
    
 
   
    FOREIGN CURRENCY FORWARD CONTRACTS.  Each Portfolio may enter into foreign
currency forward contracts ("forward contracts") that provide for the purchase
or sale of an amount of a specified currency at a future date. The Portfolios
may use such contracts to protect against a decline in a foreign currency
against the U.S. dollar between the trade date and settlement date when the
Portfolio purchases or sells securities, lock in the U.S. dollar value of
dividends and interest on securities held by the Portfolio, and generally to
protect the U.S. dollar value of securities held by the Portfolio against
exchange rate fluctuation. While forward contracts may limit losses as a result
of exchange rate fluctuations, they will also limit any gains that might
otherwise have been realized. The Portfolio's Custodian may be required to place
cash or liquid securities in a segregated account in an amount equal to the
value of the Portfolio's total assets committed to the consummation of forward
contracts. If the value of the securities placed in the segregated account
declines, additional cash or securities will be placed in the account on a daily
basis so that the value of the account will be at least equal to the amount of
the Portfolio's commitments with respect to such contracts.
    
 
    FOREIGN INVESTMENT.  Investment in securities of foreign issuers involves
somewhat different investment risks than those affecting securities of U.S.
domestic issuers. There may be limited publicly available information with
respect to foreign issuers, and foreign issuers are not generally subject to
uniform accounting, auditing and financial and other reporting standards and
requirements comparable to those applicable to U.S. companies. There may also be
less government supervision and regulation of foreign securities exchanges,
brokers and listed companies than in the United States. Many foreign securities
markets have substantially less volume than U.S. national securities exchanges,
and securities of some foreign issuers are less liquid and more volatile than
securities of comparable domestic issuers. Brokerage commissions and other
transaction costs on foreign securities exchanges are generally higher than in
the United States. Dividends and interest paid by foreign issuers may be subject
to withholding and other foreign taxes, which may decrease the net return on
foreign investments as compared to dividends and interest paid to the Portfolios
by domestic companies, and it is not expected that a Portfolio or its
shareholders would be able to claim a credit for U.S. tax purposes with respect
to any such foreign taxes. Additional risks include future political and
economic developments, the possibility that a foreign jurisdiction might impose
or change withholding taxes on income payable with respect to foreign
securities, possible seizure, nationalization or expropriation of the foreign
issuer or foreign deposits and the
 
                                       25
<PAGE>
possible adoption of foreign governmental restrictions such as exchange
controls. Many of the emerging countries may have less stable political
environments than more developed countries. Also, it may be more difficult to
obtain a judgment in a court outside the United States.
 
    Investments in securities of foreign issuers are frequently denominated in
foreign currencies, and the Portfolios may temporarily hold uninvested reserves
in bank deposits in foreign currencies. Therefore, the value of each Portfolio's
assets as measured in U.S. dollars may be affected favorably or unfavorably by
changes in currency rates and in exchange control regulations, and the
Portfolios may incur costs in connection with conversions between various
currencies.
 
   
    The Asian Equity Portfolio may invest in securities of issuers located in
Hong Kong. Hong Kong was established as a British colony in the 1840's and has
been ruled by the British Government through an appointed Governor. Effective
July 1, 1997, Hong Kong reverts to Chinese sovereignty and will be ruled as a
Special Administrative Region of China. Although China has made certain
commitments to preserve the economic and social freedoms currently enjoyed in
Hong Kong, there can be no assurances China's commitments will be maintained.
Action taken by the Chinese government which limits or causes uncertainty with
regard to these economic and social freedoms could have an adverse affect on the
Portfolio's investments in securities of issuers located in Hong Kong.
    
 
   
    FUTURES CONTRACTS AND OPTIONS ON FUTURES CONTRACTS.  The Latin American
Portfolio may purchase and sell futures contracts and options on futures
contracts, including but not limited to financial futures, securities index
futures, foreign currency exchange futures, and interest rate futures contracts.
Futures contracts provide for the sale by one party and purchase by another
party of a specified amount of a specific security, instrument or basket
thereof, at a specific future date and at a specified price. An option on a
futures contract is a legal contract that gives the holder the right to buy or
sell a specified amount of futures contracts at a fixed or determinable price
upon the exercise of the option.
    
 
   
    The Portfolio may sell securities index futures contracts and/or options
thereon in anticipation of or during a market decline to attempt to offset the
decrease in market value of investments in its portfolio, or purchase securities
index futures in order to gain market exposure. Subject to applicable laws, the
Portfolio may engage in transactions in securities index futures contracts (and
options thereon) which are traded on a recognized securities or futures
exchange, or may purchase or sell such instruments in the over-the-counter
market. There currently are limited securities index futures and options on such
futures in many countries, particularly emerging countries. The nature of the
strategies adopted by the Adviser, and the extent to which those strategies are
used, may depend on the development of such markets.
    
 
   
    The Portfolio may engage in transactions involving foreign currency exchange
futures contracts. Such contracts involve an obligation to purchase or sell a
specific currency at a specified future date and at a specified price. The
Portfolio may engage in such transactions to hedge their respective holdings and
commitments against changes in the level of future currency rates or to gain
exposure to a particular currency.
    
 
   
    The Portfolio may engage in transactions in interest rate futures
transactions. Interest rate futures contracts involve an obligation to purchase
or sell a specific debt security, instrument or basket thereof at a specified
future date at a specified price. The value of the contract rises and falls
inversely with changes in interest rates. The Portfolio may engage in such
transactions to hedge their holdings of debt instruments against future changes
in interest rates.
    
 
                                       26
<PAGE>
   
    Financial futures are futures contracts relating to financial instruments,
such as U.S. Government securities, foreign currencies, and certificates of
deposit. Such contracts involve an obligation to purchase or sell a specific
security, instrument or basket thereof at a specified future date at a specified
price. Like interest rate futures contracts, the value of financial futures
contracts rises and falls inversely with changes in interest rates. The
Portfolio may engage in financial futures contracts for hedging and non-hedging
purposes.
    
 
   
    Under rules adopted by the Commodity Futures Trading Commission, the
Portfolio may enter into futures contracts and options thereon for both hedging
and non-hedging purposes, provided that not more than 5% of the Portfolio's
total assets at the time of entering the transaction are required as margin and
option premiums to secure obligations under such contracts relating to
activities that do not constitute "bona-fide" hedging. The Portfolio will not
enter into futures contracts to the extent that its outstanding obligations to
purchase securities under such contracts, in combination with its outstanding
obligations with respect to options transactions (including options to purchase
securities or instruments) would exceed 20% of its total assets.
    
 
   
    Gains and losses on futures contracts and options thereon depend on the
Adviser's ability to predict correctly the direction of securities prices,
interest rates and other economic factors. Other risks associated with the use
of futures and options are (i) imperfect correlation between the change in
market value of investments held by the Portfolio and the prices of futures and
options relating to investments purchased or sold by the Portfolio, and (ii)
possible lack of a liquid secondary market for a futures contract and the
resulting inability to close a futures position. The risk that the Portfolio
will be unable to close out a futures position or options contract will be
minimized by only entering into futures contracts or options transactions for
which there appears to be a liquid exchange or secondary market. The risk of
loss in trading on futures contracts in some strategies can be substantial, due
both to the low margin deposits required and the extremely high degree of
leverage involved in futures pricing.
    
 
    INVESTMENT FUNDS.  Some emerging countries have laws and regulations that
currently preclude direct foreign investment in the securities of their
companies. However, indirect foreign investment in the securities of companies
listed and traded on the stock exchanges in these countries is permitted by
certain emerging countries through investment funds which have been specifically
authorized. The Latin American Portfolio may invest in these investment funds
subject to the provisions of the 1940 Act and other applicable laws as discussed
below under "Investment Restrictions." If the Portfolio invests in such
investment funds, the Portfolio's shareholders will bear not only their
proportionate share of the expenses of the Portfolio (including operating
expenses and the fees of the Adviser), but also will indirectly bear similar
expenses of the underlying investment funds.
 
    Certain of the investment funds referred to in the preceding paragraph are
advised by the Adviser. The Portfolio may, to the extent permitted under the
1940 Act and other applicable law, invest in these investment funds. If the
Portfolio does elect to make an investment in such an investment fund, it will
only purchase the securities of such investment fund in the secondary market.
 
    LOANS OF PORTFOLIO SECURITIES.  Each Portfolio may lend its securities to
brokers, dealers, domestic and foreign banks or other financial institutions for
the purpose of increasing its net investment income. These loans must be secured
continuously by cash or equivalent collateral or by a letter of credit at least
equal to the market value of the securities loaned plus accrued interest or
income. There may be risks of delay in recovery of the
 
                                       27
<PAGE>
securities or even loss of rights in the collateral should the borrower of the
securities fail financially. A Portfolio will not enter into securities loan
transactions exceeding in the aggregate 33 1/3% (20% for the Latin American
Portfolio) of the market value of the Portfolio's total assets.
 
    LOWER RATED DEBT SECURITIES.  The Latin American Portfolio may invest in
lower rated or unrated debt securities, commonly referred to as "junk bonds." In
addition, the emerging country debt securities in which the Portfolio may invest
will not be required to meet a minimum rating standard and may not be rated.
Fixed income securities are subject to the risk of an issuer's inability to meet
principal and interest payments on the obligations (credit risk) and may also be
subject to price volatility due to such factors as interest rate sensitivity,
market perception of the creditworthiness of the issuer and general market
liquidity (market risk). Lower rated or unrated securities are more likely to
react to developments affecting market and credit risk than are more highly
rated securities, which react primarily to movements in the general level of
interest rates. The market values of fixed-income securities tend to vary
inversely with the level of interest rates. Yields and market values of lower
rated and unrated debt securities will fluctuate over time, reflecting not only
changing interest rates but the market's perception of credit quality and the
outlook for economic growth. When economic conditions appear to be
deteriorating, medium to lower rated securities may decline in value due to
heightened concern over credit quality, regardless of prevailing interest rates.
Fluctuations in the value of the Portfolio's investments will be reflected in
the Portfolio's net asset value per share. The Adviser considers both credit
risk and market risk in making investment decisions for the Portfolio. Investors
should carefully consider the relative risks of investing in lower rated and
unrated debt securities and understand that such securities are not generally
meant for short-term investing.
 
    The market for lower rated and unrated debt securities is relatively new and
adverse economic developments may disrupt the market for lower rated and unrated
emerging country debt securities. Such disruptions may severely affect the
ability of issuers, especially highly leveraged issuers, to service their debt
obligations or to repay their obligations upon maturity. In addition, the
secondary market for lower rated and unrated debt securities, which is
concentrated in relatively few market makers, may not be as liquid as the
secondary market for more highly rated securities. As a result, the Adviser
could find it more difficult to sell these securities or may be able to sell the
securities only at prices lower than if such securities were widely traded. In
addition there may be limited trading markets for debt securities of issuers
located in emerging countries. Prices realized upon the sale of such lower rated
or unrated securities, under these circumstances, may be less than the prices
used in calculating the Portfolio's net asset value.
 
    Lower rated or unrated debt obligations also present risks based on payment
expectations. If an issuer calls the obligations for redemption, the Portfolio
may have to replace the security with a lower yielding security, resulting in a
decreased return for investors. If the Portfolio experiences unexpected net
redemptions, it may be forced to sell its higher rated securities, resulting in
a decline in the overall credit quality of the Portfolio's investment portfolio
and increasing the exposure of the Portfolio to the risks of lower rated and
unrated debt securities.
 
    MONEY MARKET INSTRUMENTS.  The Portfolios are permitted to invest in money
market instruments, although each Portfolio intends to stay invested in
securities satisfying its primary investment objective to the extent practical.
Each Portfolio may make money market investments pending other investment or
settlement for liquidity, or in adverse market conditions. See "Temporary
Investments." The money market investments
 
                                       28
<PAGE>
   
permitted for the Portfolios include obligations of the U.S. Government and its
agencies and instrumentalities; obligations of foreign sovereignties; other debt
securities; commercial paper; bank obligations; certificates of deposit
(including Eurodollar certificates of deposit); and repurchase agreements.
    
 
    NON-PUBLICLY TRADED SECURITIES, PRIVATE PLACEMENTS AND RESTRICTED
SECURITIES.  The Asian Equity, International Small Cap Portfolio and the Latin
American Portfolio may invest in securities that are neither listed on a stock
exchange nor traded over-the-counter, including privately placed securities.
Such unlisted equity securities may involve a higher degree of business and
financial risk that can result in substantial losses. As a result of the absence
of a public trading market for these securities, they may be less liquid than
publicly traded securities. Although these securities may be resold in privately
negotiated transactions, the prices realized from these sales could be less than
those originally paid by the Portfolios or less than what may be considered the
fair value of such securities. Further, companies whose securities are not
publicly traded may not be subject to the disclosure and other investor
protection requirements which might be applicable if their securities were
publicly traded. If such securities are required to be registered under the
securities laws of one or more jurisdictions before being resold, the Portfolios
may be required to bear the expenses of registration.
 
    As a general matter, each Portfolio may not invest more than 15% of its net
assets in illiquid securities, including securities for which there is no
readily available secondary market. Nor as a general matter, may each Portfolio
invest more than 10% of its total assets in securities that are restricted from
sale to the public without registration ("Restricted Securities") under the
Securities Act of 1933, as amended (the "1933 Act"). However, each Portfolio may
invest up to 25% of its total assets in liquid Restricted Securities that can be
offered and sold to qualified institutional buyers under Rule 144A under the
1933 Act ("Rule 144A Securities"). The Board of Directors has adopted guidelines
and delegated to the Adviser, subject to the supervision of the Board of
Directors, the daily function of determining and monitoring the liquidity of
Rule 144A Securities. Rule 144A Securities may become illiquid if qualified
institutional buyers are not interested in acquiring the securities.
 
   
    OPTIONS TRANSACTIONS.  The Latin American Portfolio may seek to increase its
return or may hedge its portfolio investments through options transactions with
respect to securities, instruments, indices or baskets thereof in which the
Portfolio may invest, as well as with respect to foreign currency. Purchasing a
put option gives the Portfolio the right to sell a specified security, currency
or basket of securities or currencies at the exercise price until the expiration
of the option. Purchasing a call option gives the Portfolio the right to
purchase a specified security, currency or basket of securities or currencies at
the exercise price until the expiration of the option. The Portfolio may not
purchase call and put options to the extent that the value of its aggregate
investment in options exceeds 5% of its total assets.
    
 
   
    The Portfolio also may write (i.e. sell) put and call options on investments
held in its portfolio, as well as with respect to foreign currency. A Portfolio
that has written an option receives a premium, which increases the Portfolio's
return on the underlying security or instrument in the event the option expires
unexercised or is closed out at a profit. However, by writing a call option, the
Portfolio will limit its opportunity to profit from an increase in the market
value of the underlying security or instrument above the exercise price of the
option for as long as the Portfolio's obligation as writer of the option
continues. The Portfolio may only write options that are "covered." A covered
call option means that so long as the Portfolio is obligated as the writer of
the option, it will own (i) the underlying security or instrument subject to the
option or (ii) securities or instruments convertible or exchangeable without the
payment of any consideration into the security or instrument subject to the
option.
    
 
                                       29
<PAGE>
   
    By writing (or selling) a put option, the Portfolio incurs an obligation to
buy the security or instrument underlying the option from the purchaser of the
put at the option's exercise price at any time during the option period, at the
purchaser's election. Options written by the Portfolio may be exercisable by the
purchaser only on a specific date. A Portfolio that has written a put option
will earmark or segregate sufficient liquid assets to cover its obligations
under the option.
    
 
   
    The Portfolio may engage in transactions in options which are traded on
recognized exchanges or over-the-counter. There currently are limited options
markets in many countries, particularly emerging countries such as Latin
American countries, and the nature of the strategies adopted by the Adviser and
the extent to which those strategies are used will depend on the development of
such option markets. The primary risks associated with the use of options are
(i) imperfect correlation between the change in market value of investments
held, purchased or sold by the Portfolio and the prices of options relating to
such investments; and (ii) possible lack of a liquid secondary market for an
option.
    
 
    REPURCHASE AGREEMENTS.  Each Portfolio may enter into repurchase agreements
with brokers, dealers or banks that meet the credit guidelines established by
the Fund's Board of Directors. In a repurchase agreement, the Portfolio buys a
security from a seller that has agreed to repurchase it at a mutually agreed
upon date and price, reflecting the interest rate effective for the term of the
agreement. The term of these agreements is usually from overnight to one week
and never exceeds one year. Repurchase agreements may be viewed as a fully
collateralized loan of money by the Portfolio to the seller. The Portfolio
always receives securities with a market value at least equal to the purchase
price (including accrued interest) as collateral, and this value is maintained
during the term of the agreement. If the seller defaults and the collateral
value declines, the Portfolio might incur a loss. If bankruptcy proceedings are
commenced with respect to the seller, the Portfolio's realization upon the
collateral may be delayed or limited. The Portfolio may not enter into
repurchase agreements with more than seven days to maturity if, as a result,
more than 15% of the market value of the Portfolio's net assets are invested in
these agreements and other investments for which market quotations are not
readily available or which are otherwise illiquid.
 
    SHORT SALES.  The Latin American Portfolio may from time to time sell
securities short without limitation, but consistent with applicable legal
requirements, although at present the Portfolio does not intend to sell
securities short. A short sale is a transaction in which the Portfolio sells
securities it owns or has the right to acquire at no added cost (i.e., "against
the box") or does not own (but has borrowed) in anticipation of a decline in the
market price of the securities. To deliver the securities to the buyer, the
Portfolio arranges through a broker to borrow the securities and, in so doing,
the Portfolio becomes obligated to replace the securities borrowed at their
market price at the time of replacement. When the Portfolio makes a short sale,
the proceeds it receives from the sale will be held on behalf of a broker until
the Portfolio replaces the borrowed securities. The Portfolio may have to pay a
premium to borrow the securities and must pay any dividends or interest payable
on the securities until they are replaced.
 
   
    The Portfolio's obligation to replace the securities borrowed in connection
with a short sale will be secured by collateral deposited with the broker that
consists of cash or other liquid securities. In addition, the Portfolio will
place in a segregated account with its Custodian an amount of cash or other
liquid securities equal to the difference, if any, between (1) the market value
of the securities sold at the time they were sold short and (2) any cash or
other liquid securities deposited as collateral with the broker in connection
with the short sale. Short
    
 
                                       30
<PAGE>
sales by the Portfolio involve certain risks and special considerations.
Possible losses from short sales differ from losses that could be incurred from
a purchase of a security, because losses from short sales may be unlimited,
whereas losses from purchases can equal only the total amount invested.
 
   
    TEMPORARY INVESTMENTS.  For temporary defensive purposes, when the Adviser
determines that market conditions warrant, each Portfolio may invest up to 100%
of its assets in dollar and non-dollar denominated money market instruments and
short- and medium-term debt securities that the Adviser believes to be of high
quality, or hold cash. The short- and medium-term debt securities in which a
Portfolio may invest consist of (a) obligations of the U.S. or foreign country
governments, their respective agencies or instrumentalities; (b) bank deposits
and bank obligations (including certificates of deposit, time deposits and
bankers' acceptances) of U.S. or foreign country banks denominated in any
currency; (c) floating rate securities and other instruments denominated in any
currency issued by international development agencies; (d) finance company and
corporate commercial paper and other short-term corporate debt obligations of
U.S. and foreign country corporations meeting the Portfolio's credit quality
standards; and (e) repurchase agreements with banks and broker-dealers with
respect to such securities.
    
 
    WHEN-ISSUED AND DELAYED DELIVERY SECURITIES.  Each Portfolio may purchase
securities on a when-issued or delayed delivery basis. In such transactions,
instruments are bought with payment and delivery taking place in the future in
order to secure what is considered to be an advantageous yield or price at the
time of the transaction. Delivery of and payment for these securities may take
as long as a month or more after the date of the purchase commitment but will
take place no more than 120 days after the trade date. Each Portfolio will
maintain with the Custodian a separate account with a segregated portfolio of
cash or liquid securities in an amount at least equal to these commitments. The
payment obligation and the interest rates that will be received are each fixed
at the time a Portfolio enters into the commitment and no interest accrues to
the Portfolio until settlement. Thus, it is possible that the market value at
the time of settlement could be higher or lower than the purchase price if,
among other factors, the general level of interest rates has changed. It is a
current policy of each Portfolio not to enter into when-issued commitments or
delayed delivery securities exceeding in the aggregate 15% of the market value
of the Portfolio's total assets less liabilities, other than the obligations
created by these commitments.
 
                             INVESTMENT LIMITATIONS
 
    Each Portfolio, except the Latin American Portfolio, is a diversified
investment company under the 1940 Act and is therefore subject to the following
limitations: (a) as to 75% of its total assets, a Portfolio may not invest more
than 5% of its total assets in the securities of any one issuer, except
obligations of the U.S. Government and its agencies and instrumentalities, and
(b) a Portfolio may not own more than 10% of the outstanding voting securities
of any one issuer. The Latin American Portfolio is a non-diversified investment
company under the 1940 Act, which means that the Latin American Portfolio is not
limited by the 1940 Act in the proportion of its total assets that may be
invested in the obligations of a single issuer. Thus, the Latin American
Portfolio may invest a greater proportion of its total assets in the securities
of a smaller number of issuers and, as a result, will be subject to greater risk
with respect to its portfolio securities. Nevertheless, the Latin American
Portfolio intends to comply with the more limited diversification requirements
imposed by the Internal Revenue Code of 1986, as amended (the "Code") for
qualification as a regulated investment company.
 
                                       31
<PAGE>
    Each Portfolio also operates under certain investment restrictions that are
deemed fundamental limitations and may be changed only with the approval of the
holders of a majority of such Portfolio's outstanding shares and under certain
non-fundamental investment limitations that may be changed without shareholder
approval. For additional information on fundamental and non-fundamental
investment limitations, see "Investment Limitations" in the Statement of
Additional Information.
 
                             MANAGEMENT OF THE FUND
 
    INVESTMENT ADVISER.  Morgan Stanley Asset Management Inc. is the Adviser and
Administrator of the Fund and each Portfolio. The Adviser provides investment
advice and portfolio management services, pursuant to an Investment Advisory
Agreement and, subject to the supervision of the Fund's Board of Directors,
makes each of the Portfolio's day-to-day investment decisions, arranges for the
execution of portfolio transactions and generally manages each of the
Portfolio's investments. Set forth below as an annual percentage of average
daily net assets are the management fees payable to the Adviser quarterly by
each Portfolio pursuant to the terms of the Investment Advisory Agreement. The
fee for each of the Portfolios is higher than most investment companies' because
each of the Portfolios invests internationally. The Adviser believes that the
fees are comparable to those of other investment companies that invest
internationally. The Adviser has agreed to a reduction in the fees payable to it
and to reimburse the Portfolios, if necessary, if such fees would cause total
annual operating expenses of the Portfolios to exceed the maximums set forth in
the table below.
 
   
<TABLE>
<CAPTION>
                                                                    MAXIMUM TOTAL ANNUAL
                                                                         OPERATING
                                              MANAGEMENT FEES    EXPENSES AFTER FEE WAIVERS
                                                ABSENT FEE       --------------------------
PORTFOLIO                                         WAIVERS          CLASS A       CLASS B
- ------------------------------------------  -------------------  ------------  ------------
<S>                                         <C>                  <C>           <C>
Global Equity                                        0.80%             1.00%         1.25%
International Equity                                 0.80%             1.00%         1.25%
International Small Cap                              0.95%             1.15%          N/A
Asian Equity                                         0.80%             1.00%         1.25%
European Equity                                      0.80%             1.00%         1.25%
Japanese Equity                                      0.80%             1.00%         1.25%
Latin American                                       1.10%             1.70%         1.95%
</TABLE>
    
 
   
    The Adviser, with principal offices at 1221 Avenue of the Americas, New
York, New York 10020, conducts a worldwide portfolio management business and
provides a broad range of portfolio management services to customers in the
United States and abroad. On February 5, 1997, Morgan Stanley Group Inc. and
Dean Witter, Discover & Co. announced that they had entered into an Agreement
and Plan of Merger to form Morgan Stanley, Dean Witter, Discover & Co. Morgan
Stanley Group Inc. is the direct parent of the Adviser and Morgan Stanley.
Subject to certain conditions being met, it is currently anticipated that the
transaction will close in mid-1997. Thereafter, the Adviser and Morgan Stanley
will be subsidiaries of Morgan Stanley, Dean Witter, Discover & Co. At March 31,
1997, the Adviser, together with its affiliated asset management companies,
managed investments totaling in excess of $118 billion, including approximately
$100 billion under active management and $18 billion as Named Fiduciary or
Fiduciary Adviser. See "Management of the Fund" in the Statement of Additional
Information.
    
 
                                       32
<PAGE>
    PORTFOLIO MANAGERS.  The following individuals have primary portfolio
management responsibility for the Portfolios noted below:
 
   
    GLOBAL EQUITY PORTFOLIO -- FRANCES CAMPION.  Frances Campion joined the
Adviser in January 1990 as a Global Equity Fund Manager and is now a Principal
of Morgan Stanley. Her responsibilities include day to day management of the
Global Equity product. Prior to joining the Adviser, Ms. Campion was a U.S.
equity analyst with Lombard Odier Limited where she had responsibility for the
management of global portfolios. Ms. Campion has ten years global investment
experience. She is a graduate of University College, Dublin.
    
 
    INTERNATIONAL EQUITY PORTFOLIO -- DOMINIC CALDECOTT.  Dominic Caldecott is a
Managing Director and is responsible for research and stock selection in the
Pacific Basin and has been primarily responsible for managing the Portfolio's
assets since its inception. He has ten years professional experience, primarily
in Tokyo, Hong Kong, and Seoul. Prior to joining Morgan Stanley, he worked with
GT Management Group in Tokyo and Hong Kong, specializing in Pacific Basin
investment management. He became a Vice President of Morgan Stanley in 1987, a
Principal in 1989, and a Managing Director in 1991. He is responsible for a
number of Pacific Basin investment programs for clients of Morgan Stanley. Mr.
Caldecott is a graduate of New College, Oxford, England.
 
    INTERNATIONAL SMALL CAP PORTFOLIO -- MARGARET NAYLOR.  Margaret Naylor is a
Principal of Morgan Stanley and works with Dominic Caldecott on Pacific Basin
research and stock selection. She joined the Adviser in March 1987 and has been
primarily responsible for managing the Portfolio's assets since December 1992.
Prior to joining the Adviser she spent three years at the Trade Policy Research
Centre, an independent research unit. Ms. Naylor is a graduate of the University
of York. Ms. Naylor became a Vice President of Morgan Stanley in 1993.
 
    ASIAN EQUITY PORTFOLIO -- EAN WAH CHIN.  Ean Wah Chin is a Managing Director
of Morgan Stanley, and is responsible for the Adviser's regional Asia ex-Japan
operations based in Singapore. She has been primarily responsible for managing
the Portfolio's assets since its inception. Prior to joining Morgan Stanley in
1986, Ms. Chin spent eight years with the Monetary Authority of Singapore and
the Government of Singapore Investment Corporation, where she was a portfolio
manager of one of the largest portfolios in Asia. Ms. Chin was an ASEAN scholar
educated at the University of Singapore.
 
    EUROPEAN EQUITY PORTFOLIO -- ROBERT SARGENT.  Robert Sargent joined Morgan
Stanley International in May, 1986, and transferred to the Adviser in June,
1987. Mr. Sargent is now a Principal of Morgan Stanley and has been primarily
responsible for managing the Portfolio's assets since its inception. As the fund
manager with primary responsibility for continental European stock selection and
portfolio management, Mr. Sargent is closely involved with the Adviser's
fundamental research effort and company visiting program. He is a graduate of
York University, Toronto, Canada.
 
    JAPANESE EQUITY PORTFOLIO -- DOMINIC CALDECOTT AND KUNIHIKO
SUGIO.  Information about Mr. Caldecott is included under International Equity
Portfolio above. Mr. Caldecott is responsible for research and stock selection
in the Pacific Basin and has been primarily responsible for managing the
Portfolio's assets since its inception. Kunihiko Sugio joined the Adviser in
December 1993 as a Vice President and manages dedicated Japanese equity
portfolios. He has been primarily responsible for managing the Portfolio's
assets since its inception. Prior to joining Morgan Stanley, he worked with
Baring International Investment Management, Tokyo, where he was a Director and
fund manager. He graduated from Wakayama Kokuritsu University.
 
                                       33
<PAGE>
    LATIN AMERICAN PORTFOLIO -- ROBERT L. MEYER.  Robert Meyer joined the
Adviser in 1989 and is now a Principal of Morgan Stanley, with primary
responsibility for the Adviser's investments in all of Latin America and Israel.
He has had primary responsibility for managing the Portfolio's assets since its
inception. Robert is co-manager of the Latin American Discovery Fund, Inc. and
worked previously in the U.S. equity group at the Adviser. He was born in
Argentina and has a B.A. in Economics and Political Science from Yale College
and a J.D. from Harvard Law School.
 
    ADMINISTRATOR.  The Adviser also provides administrative services to the
Fund pursuant to an Administration Agreement. The services provided under the
Administration Agreement are subject to the supervision of the Officers and
Board of Directors of the Fund and include day-to-day administration of matters
related to the corporate existence of the Fund, maintenance of its records,
preparation of reports, supervision of the Fund's arrangements with its
custodian and assistance in the preparation of the Fund's registration
statements under federal laws. The Administration Agreement also provides that
the Administrator, through its agents, will provide dividend disbursing and
transfer agent services to the Fund. For its services under the Administration
Agreement, the Fund pays the Adviser a monthly fee which on an annual basis
equals 0.15% of the average daily net assets of each Portfolio.
 
   
    Under an agreement between the Adviser and The Chase Manhattan Bank
("Chase"), Chase provides certain administrative services to the Fund through
its corporate affiliate, Chase Global Funds Services Company ("CGFSC"). The
Adviser supervises and monitors such administrative services provided by CGFSC.
Their services are also subject to the supervision of the Board of Directors of
the Fund. CGFSC's business address is 73 Tremont Street, Boston, Massachusetts
02108-3913.
    
 
    LOCAL ADMINISTRATORS FOR THE LATIN AMERICAN PORTFOLIO.  The Portfolio has,
as required by local law, entered into administration agreements with local
administrators in Brazil, Chile, and Colombia. A local administrator provides
certain services for the Portfolio with respect to the Portfolio's investments
in that country, including services relating to foreign exchange, local taxes,
remittance of income and capital gains, and repatriation of investments. The
Portfolio's local administrator in Brazil, Unibanco-Uniao, a Brazilian
corporation, is paid by the Fund an annual fee of 0.125% of the Portfolio's
average weekly net assets invested in Brazil. The Portfolio's local
administrator in Chile, Bice Chileconsult Agente de Valores S.A., a Chilean
corporation, is paid by the Fund an annual fee of 0.125% of the Portfolio's
average weekly net assets invested in Chile. The Portfolio's local administrator
in Colombia, CitiTrust S.A., a Colombian trust company, is paid by the Fund an
annual fee of $1,000 plus 0.20% per transaction in Colombia.
 
    DIRECTORS AND OFFICERS.  Pursuant to the Fund's Articles of Incorporation,
the Board of Directors decides upon matters of general policy and reviews the
actions of the Fund's Adviser, Administrator, Distributor and other service
providers. The Officers of the Fund conduct and supervise its daily business
operations.
 
    DISTRIBUTOR.  Morgan Stanley serves as the exclusive Distributor of the
shares of the Fund. Under its Distribution Agreement with the Fund, Morgan
Stanley sells shares of each Portfolio upon the terms and at the current
offering price described in this Prospectus. Morgan Stanley is not obligated to
sell any certain number of shares of any Portfolio.
 
    The Portfolios currently offer only the classes of shares offered by this
Prospectus. The Portfolios may in the future offer one or more classes of shares
with features, distribution expenses or other expenses that are different from
those of the classes currently offered.
 
                                       34
<PAGE>
    The Fund has adopted a Plan of Distribution with respect to the Class B
shares of each Multiclass Portfolio pursuant to Rule 12b-1 under the 1940 Act
(each, a "Plan"). Under each Plan, the Distributor is entitled to receive from
each Multiclass Portfolio a distribution fee, which is accrued daily and paid
quarterly, of 0.25% of the Class B shares' average daily net assets on an
annualized basis. The Distributor expects to reallocate most of its fee to its
investment representatives. The Distributor may, in its discretion, voluntarily
waive from time to time all or any portion of its distribution fee and each of
the Distributor and the Adviser is free to make additional payments out of its
own assets to promote the sale of Fund shares, including payments that
compensate financial institutions for distribution services or shareholder
services.
 
    Each Plan is designed to compensate the Distributor for its services, not to
reimburse the Distributor for its expenses, and the Distributor may retain any
portion of the fee that it does not expend in fulfillment of its obligations to
the Fund.
 
    EXPENSES.  Each Portfolio is responsible for payment of certain other fees
and expenses (including legal fees, accountant's fees, custodial fees and
printing and mailing costs) specified in the Administration and Distribution
Agreements.
 
                               PURCHASE OF SHARES
 
    Class A shares of each Portfolio and Class B shares of each Multiclass
Portfolio may be purchased at the net asset value per share next determined
after receipt of the purchase order by the Portfolio. See "Valuation of Shares."
Shareholders of the International Small Cap Portfolio may be charged a 1.00%
transaction fee, which is payable directly to the International Small Cap
Portfolio, in connection with each purchase and redemption of shares of the
Portfolio. The transaction fee is intended to allocate transaction costs
associated with purchases and redemptions of shares of the Portfolio to
investors actually making such purchases and redemptions rather than to the
Portfolio's other shareholders. The 1.00% fee represents the Adviser's estimate
of such transaction costs, which include the costs of acquiring and disposing of
Portfolio securities. The transaction fee is not a sales charge or load, and is
retained by the Portfolio. The fee does not apply to Portfolios of the Fund
other than the International Small Cap Portfolio and is not charged in
connection with the reinvestment of dividends or capital gain distributions. The
fee will not be charged with respect to purchases and redemptions that do not
result in actual transaction costs to the Portfolio.
 
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
 
    For a Portfolio account opened on or after January 2, 1996 (a "New
Account"), the minimum initial investment and minimum account size are $500,000
for Class A shares and $100,000 for Class B shares of each Portfolio. Certain
advisory or asset allocation accounts, such as Total Funds Management accounts,
managed by Morgan Stanley or its affiliates, including the Adviser ("Managed
Accounts") may purchase Class A shares without being subject to such minimum
initial investment or minimum account size requirements for a Portfolio account.
Employees of the Adviser and certain of its affiliates may purchase Class A
shares subject to conditions, including a lower minimum initial investment,
established by Officers of the Fund.
 
    If the value of a New Account containing Class A shares falls below $500,000
(but remains at or above $100,000) because of shareholder redemption(s), the
Fund will notify the shareholder, and if the account value remains below
$500,000 (but remains at or above $100,000) for a continuous 60-day period, the
Class A shares in such account will convert to Class B shares and will be
subject to the distribution fee and other features
 
                                       35
<PAGE>
applicable to the Class B shares. The Fund, however, will not convert Class A
shares to Class B shares based solely upon changes in the market that reduce the
net asset value of shares. Under current tax law, conversions between share
classes are not a taxable event to the shareholder.
 
    Shares in a Portfolio account opened prior to January 2, 1996 (a "Pre-1996
Account") were designated Class A shares on January 2, 1996. Shares in a
Pre-1996 Account with a value of $100,000 or more on March 1, 1996 (a
"Grandfathered Class A Account") remained Class A shares regardless of account
size thereafter. Except for shares in a Managed Account, shares in a Pre-1996
Account with a value of less than $100,000 on March 1, 1996 (a "Grandfathered
Class B Account") converted to Class B shares on March 1, 1996. Grandfathered
Class A Accounts and Managed Accounts are not subject to conversion from Class A
shares to Class B shares.
 
    Investors may also invest in the Fund by purchasing shares through a trust
department, broker, dealer, agent, financial planner, financial services firm or
investment adviser. An investor may be charged an additional service or
transaction fee by that institution.
 
   
    The minimum investment levels may be waived at the discretion of the Adviser
for (i) certain employees and customers of Morgan Stanley or its affiliates and
certain trust departments, brokers, dealers, agents, financial planners,
financial services firms, or investment advisers that have entered into an
agreement with Morgan Stanley or its affiliates; and (ii) retirement and
deferred compensation plans and trusts used to fund such plans, including, but
not limited to, those defined in Section 401(a), 403(b) or 457 of the Code and
"rabbi trusts." The Fund reserves the right to modify or terminate the
conversion features of the shares as stated above at any time upon 60-days
notice to shareholders.
    
 
    The Adviser reserves the right in its sole discretion to determine which of
such advisory or asset allocation accounts shall be Managed Accounts. For
information regarding Managed Accounts, please contact your Morgan Stanley
account representative or the Fund at the telephone number provided on the cover
of this Prospectus.
 
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
 
    If the value of a New Multiclass Account falls below $100,000 because of
shareholder redemption(s), the Fund will notify the shareholder, and if the
account value remains below $100,000 for a continuous 60-day period, the shares
in such account are subject to redemption by the Fund and, if redeemed, the net
asset value of such shares will be promptly paid to the shareholder. The Fund,
however, will not redeem shares based solely upon changes in the market that
reduce the net asset value of shares.
 
    Grandfathered Class A Accounts, Grandfathered Class B Accounts and Managed
Accounts are not subject to involuntary redemption. If a shareholder reduces its
total investment in Class A shares of the International Small Cap Portfolio to
less than $500,000, the investment may be subject to redemption. The Fund
reserves the right to modify or terminate the involuntary redemption features of
the shares as stated above at any time upon 60-days notice to shareholders.
 
CONVERSION FROM CLASS B TO CLASS A SHARES
 
    If the value of Class B shares in a Multiclass Portfolio account increases,
whether due to shareholder share purchases or market activity, to $500,000 or
more, the Class B shares will convert to Class A shares. Under current tax law,
such conversion is not a taxable event to the shareholder. Class A shares
converted from Class B
 
                                       36
<PAGE>
shares are subject to the same minimum account size requirements that are
applicable to New Multiclass Accounts containing Class A shares, as stated
above. The Fund reserves the right to modify or terminate this conversion
feature at any time upon 60-days notice to shareholders.
 
INITIAL PURCHASES DIRECTLY FROM THE FUND
 
    The Fund's determination of an investor's eligibility to purchase shares of
a given class will take precedence over the investor's selection of a class.
Assuming the investor is eligible for the class, the Fund will select the most
favorable class for the investor, if the investor has not done so.
 
1) BY CHECK.  An account may be opened by completing and signing an Account
   Registration Form and mailing it, together with a check ($500,000 minimum for
   Class A shares of each Portfolio and $100,000 minimum for Class B shares of
   each Multiclass Portfolio, with certain exceptions for Morgan Stanley
   employees and select customers) payable to "Morgan Stanley Institutional
   Fund, Inc. -- [portfolio name]", to:
 
      Morgan Stanley Institutional Fund, Inc.
      P.O. Box 2798
      Boston, Massachusetts 02208-2798
 
Payment will be accepted only in U.S. dollars, unless prior approval for payment
in other currencies is given by the Fund. The classes of shares of the
Portfolio(s) to be purchased should be designated on the Account Registration
Form. For purchases by check, the Fund is ordinarily credited with Federal Funds
within one business day. Thus, your purchase of shares by check is ordinarily
credited to your account at the net asset value per share of the relevant
Portfolio determined on the next business day after receipt.
 
2) BY FEDERAL FUNDS WIRE.  Purchases may be made by having your bank wire
   Federal Funds to the Fund's bank account. In order to ensure prompt receipt
   of your Federal Funds Wire, it is important that you follow these steps:
 
A.  Telephone the Fund (toll free: 1-800-548-7786) and provide us with your
    name, address, telephone number, Social Security or Tax Identification
    Number, the portfolio(s) selected, the class selected, the amount being
    wired, and by which bank. We will then provide you with a Fund account
    number. (Investors with existing accounts should also notify the Fund prior
    to wiring funds.)
 
B.  Instruct your bank to wire the specified amount to the Fund's Wire
    Concentration Bank Account (be sure to have your bank include the name of
    the portfolio(s) selected, the class selected, and the account number
    assigned to you) as follows:
 
   
    The Chase Manhattan Bank
    One Manhattan Plaza
    New York, NY 10081-1000
    ABA #021000021
    DDA #910-2-733293
    Attn: Morgan Stanley Institutional Fund, Inc.
    Ref: (Portfolio name, your account number, your account name)
    
 
    Please call the Fund at 1-800-548-7786 prior to wiring funds.
 
                                       37
<PAGE>
C.  Complete and sign the Account Registration Form and mail it to the address
    shown thereon.
 
  The purchase price of the Class A and Class B shares of each Portfolio is the
  net asset value next determined after the order is received. See "Valuation of
  Shares." An order received prior to the regular close of the New York Stock
  Exchange ("NYSE"), which is currently 4:00 p.m. Eastern Time, will be executed
  at the price computed on the date of receipt; an order received after the
  regular close of the NYSE will be executed at the price computed on the next
  day the NYSE is open as long as the Transfer Agent receives payment by check
  or in Federal Funds prior to the regular close of the NYSE on such day.
 
  Federal Funds purchase orders will be accepted only on a day on which the Fund
  and Chase (the "Custodian Bank") are open for business. Your bank may charge a
  service fee for wiring Federal Funds.
 
3) BY BANK WIRE.  The same procedure outlined under "By Federal Funds Wire"
   above must be followed in purchasing shares by bank wire. However, money
   transferred by bank wire may or may not be converted into Federal Funds the
   same day, depending on the time the money is received and the bank handling
   the wire. Prior to such conversion, an investor's money will not be invested
   and, therefore, will not be earning dividends. Your bank may charge a service
   fee for wiring funds.
 
ADDITIONAL INVESTMENTS
 
    You may add to your account at any time (minimum additional investment
$1,000 for each portfolio, except for automatic reinvestment of dividends and
capital gains distributions for which there are no minimums) by purchasing
shares at net asset value by mailing a check to the Fund (payable to "Morgan
Stanley Institutional Fund, Inc. -- [portfolio name]") at the above address or
by wiring monies to the Custodian Bank as outlined above. It is very important
that your account name, the portfolio name and the class selected be specified
in the letter or wire to assure proper crediting to your account. In order to
ensure that your wire orders are invested promptly, you are requested to notify
one of the Fund's representatives (toll-free 1-800-548-7786) prior to the wire
date. Additional investments will be applied to purchase additional shares in
the same class held by a shareholder in a Portfolio account.
 
OTHER PURCHASE INFORMATION
 
    Although the legal rights of Class A and Class B shares will be identical,
the different expenses borne by each class will result in different net asset
values and dividends. The net asset value of Class B shares will generally be
lower than the net asset value of Class A shares as a result of the distribution
expense charged to Class B shares. It is expected, however, that the net asset
value per share of the two classes will tend to converge immediately after the
recording of dividends which will differ by approximately the amount of the
distribution expense accrual differential between the classes.
 
    In the interest of economy and convenience, and because of the operating
procedures of the Fund, certificates representing shares of the Portfolio(s)
will not be issued. All shares purchased are confirmed to you and credited to
your account on the Fund's books maintained by the Adviser or its agents. You
will have the same rights and ownership with respect to such shares as if
certificates had been issued.
 
    To ensure that checks are collected by the Fund, withdrawals of investments
made by check are not presently permitted until payment for the purchase has
been received, which may take up to eight business days after the date of
purchase. As a condition of this offering, if a purchase is cancelled due to
nonpayment or
 
                                       38
<PAGE>
because your check does not clear, you will be responsible for any loss the Fund
or its agents incur. If you are already a shareholder, the Fund may redeem
shares from your account(s) to reimburse the Fund or its agents for any loss. In
addition, you may be prohibited or restricted from making future investments in
the Fund.
 
    Investors may also invest in the Fund by purchasing shares through the
Distributor.
 
EXCESSIVE TRADING
 
   
    Frequent trades involving either substantial portfolio assets or a
substantial portion of your account or accounts controlled by you can disrupt
management of a Portfolio and raise its expenses. Consequently, in the interest
of all the stockholders of the Portfolios and the Portfolios' performance, the
Fund may in its discretion bar a stockholder that engages in excessive trading
of shares of any class of a portfolio from further purchases of shares of the
Fund for an indefinite period. The Fund considers excessive trading to be more
than one purchase and sale involving shares of the same class of a Portfolio of
the Fund within any 120-day period. As an example, exchanging shares of
portfolios of the Fund as follows amounts to excessive trading: exchanging
shares of Portfolio A for shares of Portfolio B, then exchanging shares of
Portfolio B for shares of Portfolio C and again exchanging shares of Portfolio C
for shares of Portfolio B within a 120-day period. Two types of transactions are
exempt from these excessive trading restrictions: (1) trades exclusively between
money market portfolios; and (2) trades done in connection with an asset
allocation service, such as TFM Accounts or accounts managed or advised by the
Adviser and/or any of its affiliates.
    
 
INVESTMENT IN FUNDS THROUGH A TOTAL FUNDS MANAGEMENT ("TFM") ACCOUNT
 
   
    In addition to the considerable diversification among individual securities
you receive by investing in a particular Portfolio, you can further reduce risk
by spreading your assets among several different Portfolios that each have
different risk and return characteristics. TFM is an active investment
management service managed by Morgan Stanley or its affiliates, including Morgan
Stanley Asset Management Inc. (each, a "TFM Adviser"), that allocates your
investments across a combination of either Class A or Class B shares of certain
of the Portfolios selected to meet your long-term investment objectives as well
as, in certain circumstances, your current income objectives.
    
 
   
    The TFM Adviser has developed investment strategies for TFM Accounts to meet
the diverse financial needs of different investors. You can open a TFM Account
by meeting with one of the investment professionals of a Participating Dealer
who will review your situation and help you identify your long-term investment
and/or current income objectives. After using TFM criteria to determine your
long-term investment and/or current income objectives, you can choose one of
several TFM investment strategies. Based on your chosen strategy, your initial
investment will be allocated among a number of the Class A or Class B shares of
the Portfolios. Depending on market conditions, the TFM Adviser periodically
reallocates the combination of Portfolios or the percentage amounts invested in
the shares of each Portfolio to implement your TFM investment strategy. In
addition, your TFM Account will be periodically rebalanced to maintain your TFM
strategy's current asset allocation mix, if and when the performance of one or
more of the Portfolios unbalances the strategy's mix. You will pay the TFM
Adviser a fee for the TFM Account service that is in addition to and separate
from the fees and expenses you will pay directly or indirectly as an investor in
the Portfolios. See "Fund Expenses."
    
 
    From time to time, one or more of the Portfolios used for investment by the
TFM Accounts may experience relatively large investments or redemptions due to
the TFM Account allocations or rebalancings recommended by the TFM Adviser.
These transactions will affect the Portfolios, since Portfolios that experience
redemptions as
 
                                       39
<PAGE>
   
a result of reallocations or rebalancings may have to sell portfolio securities
and Portfolios that receive additional cash will have to invest it in additional
portfolio securities. While it is impossible to predict the overall impact of
these transactions over time, there could be adverse effects on portfolio
management to the extent that Portfolios may be required to sell securities or
invest cash at times when they would not otherwise do so. These transactions
could also have tax consequences if sales of securities resulted in gains and
could also increase transaction costs. The Adviser, representing the interests
of the Portfolios, is committed to minimizing the impact of TFM Account
transactions on the Portfolios. The Adviser, however, will have a conflict in
fulfilling this responsibility in that it also serves as a TFM Adviser. In that
capacity, the Adviser, representing the interests of the TFM Accounts, also is
committed to minimizing the impact of TFM Account transactions on the Portfolios
to the extent consistent with pursuing the investment objectives of the TFM
Accounts. In addition, an affiliate of the TFM Adviser, the Distributor is
compensated on the sale, and may be compensated for distribution or shareholder
services on the sale of shares of the Portfolios. See "Purchase of Shares" and
"Shareholder Services -- Exchange Features." The Adviser will monitor the impact
of TFM Account transactions on the Portfolios.
    
 
                              REDEMPTION OF SHARES
 
    You may withdraw all or any portion of the amount in your account by
redeeming shares at any time. Please note that purchases made by check are not
permitted to be redeemed until payment of the purchase price has been collected,
which may take up to eight business days after purchase. The Fund will redeem
Class A shares of each Portfolio or Class B shares of each Multiclass Portfolio
at the next determined net asset value of shares of the applicable class. On
days that both the NYSE and the Custodian Bank are open for business, the net
asset value per share of each of the Portfolios is determined at the regular
close of trading of the NYSE (currently 4:00 p.m. Eastern Time). Shares of each
Portfolio may be redeemed by mail or telephone. No charge is made for
redemptions, except for the imposition of the 1% transaction fee described under
"Purchase of Shares" above, which may be assessed in connection with redemptions
of shares of the International Small Cap Portfolio. Any redemption proceeds may
be more or less than the purchase price of your shares depending on, among other
factors, the market value of the investment securities held by a Portfolio.
 
BY MAIL
 
    Each Portfolio will redeem its Class A or Class B shares at the net asset
value determined on the date the request is received, if the request is received
in "good order" before the regular close of the NYSE. Your request should be
addressed to Morgan Stanley Institutional Fund, Inc., P.O. Box 2798, Boston,
Massachusetts 02208-2798, except that deliveries by overnight courier should be
addressed to Morgan Stanley Institutional Fund, Inc., c/o Chase Global Funds
Services Company, 73 Tremont Street, Boston, Massachusetts 02108-3913.
 
    "Good order" means that the request to redeem shares must include the
following documentation:
 
        (a)  A letter of instruction or a stock assignment specifying the class
    and number of shares or dollar amount to be redeemed, signed by all
    registered owners of the shares in the exact names in which they are
    registered;
 
        (b) Any required signature guarantees (see "Further Redemption
    Information" below); and
 
                                       40
<PAGE>
        (c)  Other supporting legal documents, if required, in the case of
    estates, trusts, guardianships, custodianships, corporations, pension and
    profit sharing plans and other organizations.
 
    Shareholders who are uncertain of requirements for redemption should consult
with a Fund representative.
 
BY TELEPHONE
 
    Provided you have previously elected the Telephone Redemption Option on the
Account Registration Form, you can request a redemption of your shares by
calling the Fund and requesting the redemption proceeds be mailed to you or
wired to your bank. Please contact one of the Fund's representatives for further
details. In times of drastic market conditions, the telephone redemption option
may be difficult to implement. If you experience difficulty in making a
telephone redemption, your request may be made by regular mail or express mail
and it will be implemented at the net asset value next determined after it is
received. Redemption requests sent to the Fund through express mail must be
mailed to the address of the Dividend Disbursing and Transfer Agent listed under
"General Information." The Fund and the Fund's transfer agent (the "Transfer
Agent") will employ reasonable procedures to confirm that the instructions
communicated by telephone are genuine. These procedures include requiring the
investor to provide certain personal identification information at the time an
account is opened and prior to effecting each transaction requested by
telephone. In addition, all telephone transaction requests will be recorded and
investors may be required to provide additional telecopied written instructions
regarding transaction requests. Neither the Fund nor the Transfer Agent will be
responsible for any loss, liability, cost or expense for following instructions
received by telephone that either of them reasonably believes to be genuine.
 
    To change the commercial bank or account designated to receive redemption
proceeds, a written request must be sent to the Fund at the address above.
Requests to change the bank or account must be signed by each shareholder and
each signature must be guaranteed.
 
FURTHER REDEMPTION INFORMATION
 
    Normally the Fund will make payment for all shares redeemed within one
business day of receipt of the request, but in no event will payment be made
more than seven days after receipt of a redemption request in good order.
However, payments to investors redeeming shares which were purchased by check
will not be made until payment for the purchase has been collected, which may
take up to eight days after the date of purchase. The Fund may suspend the right
of redemption or postpone the date upon which redemptions are effected at times
when the NYSE is closed, or under any emergency circumstances as determined by
the Securities and Exchange Commission (the "Commission").
 
    If the Board of Directors determines that it would be detrimental to the
best interests of the remaining shareholders of a Portfolio to make payment
wholly or partly in cash, the Fund may pay the redemption proceeds in whole or
in part by a distribution in-kind of securities held by a Portfolio in lieu of
cash in conformity with applicable rules of the Commission.
Distributions-in-kind will be made in readily marketable securities. Investors
may incur brokerage charges on the sale of portfolio securities so received in
payment of redemptions.
 
    To protect your account, the Fund and its agents from fraud, signature
guarantees are required for certain redemptions to verify the identity of the
person who has authorized a redemption from your account. Please contact the
Fund for further information.
 
                                       41
<PAGE>
                              SHAREHOLDER SERVICES
 
EXCHANGE FEATURES
 
    You may exchange shares that you own in any Portfolio for shares of any
other available portfolio(s) of the Fund (other than the International Equity
Portfolio, which is closed to new investors). In exchanging for shares of a
portfolio with more than one class, the class of shares you receive in the
exchange will be determined in the same manner as any other purchase of shares
and will not be based on the class of shares surrendered for the exchange.
Consequently, the same minimum initial investment and minimum account size for
determining the class of shares received in the exchange will apply. See
"Purchase of Shares." Shares of the portfolios may be exchanged by mail or
telephone. The privilege to exchange shares by telephone is automatic and made
available without shareholder election. Before you make an exchange, you should
read the prospectus of the portfolio(s) in which you seek to invest. Because an
exchange transaction is treated as a redemption followed by a purchase, an
exchange would be considered a taxable event for shareholders subject to tax.
The exchange privilege may be modified or terminated by the Fund at any time
upon 60-days notice to shareholders.
 
BY MAIL
 
    In order to exchange shares by mail, you should include in the exchange
request the name, class of shares and account number of your current Portfolio,
the name(s) of the portfolio(s) and class(es) of shares into which you intend to
exchange shares, and the signatures of all registered account holders. Send the
exchange request to Morgan Stanley Institutional Fund, Inc., P.O. Box 2798,
Boston, Massachusetts 02208-2798.
 
BY TELEPHONE
 
   
    When exchanging shares by telephone, have ready the name, class of shares
and account number of your current Portfolio, the name(s) of the portfolio(s)
and class(es) of shares into which you intend to exchange shares, your Social
Security number or Tax I.D. number, and your account address. Requests for
telephone exchanges received prior to 4:00 p.m. (Eastern Time) are processed at
the close of business that same day based on the net asset value of the
class(es) of the portfolios involved in the exchange of shares at the close of
business. Requests received after 4:00 p.m. (Eastern Time) are processed the
next business day based on the net asset value determined at the close of
business on such day. For additional information regarding responsibility for
the authenticity of telephoned instructions, see "Redemption of Shares -- By
Telephone" above.
    
 
TRANSFER OF REGISTRATION
 
    You may transfer the registration of any of your Portfolio shares to another
person by writing to Morgan Stanley Institutional Fund, Inc., P.O. Box 2798,
Boston, Massachusetts 02208-2798. As in the case of redemptions, the written
request must be received in good order before any transfer can be made.
Transferring the registration of shares may affect the eligibility of your
account for a given class of the Portfolio's shares may result in involuntary
conversion or redemption of your shares. See "Purchase of Shares" above.
 
                              VALUATION OF SHARES
 
    The net asset value per share of a class of shares of each of the Portfolios
is determined by dividing the total market value of the Portfolio's investments
and other assets attributable to such class, less any liabilities attributable
to such class, by the total number of outstanding shares of each class of the
Portfolio. Net asset value is calculated separately for each class of the
Portfolios. Net asset value per share is determined as of the regular
 
                                       42
<PAGE>
   
close of the NYSE on each day that the NYSE is open for business. Price
information on listed securities is taken from the exchange where the security
is primarily traded. Securities listed on a U.S. securities exchange for which
market quotations are available are valued at the last quoted sale price on the
day the valuation is made. Securities listed on a foreign exchange are valued at
their closing price. Unlisted securities and listed securities not traded on the
valuation date for which market quotations are readily available are valued at a
price within a range not exceeding the current asked price nor less than the
current bid price. The current bid and asked prices are determined based on the
average of the bid and asked prices quoted on such valuation date by reputable
brokers.
    
 
    Bonds and other fixed income securities are valued according to the broadest
and most representative market, which will ordinarily be the over-the-counter
market. Net asset value includes interest on fixed income securities, which is
accrued daily. In addition, bonds and other fixed income securities may be
valued on the basis of prices provided by a pricing service when such prices are
believed to reflect the fair market value of such securities. The prices
provided by a pricing service are determined without regard to bid or last sale
prices but take into account institutional size, trading in similar groups of
securities and any developments related to the specific securities. Securities
not priced in this manner are valued at the most recently quoted bid price or,
when securities exchange valuations are used, at the latest quoted sale price on
the day of valuation. If there is no such reported sale, the latest quoted bid
price will be used. Securities purchased with remaining maturities of 60 days or
less are valued at amortized cost, if it approximates market value. In the event
that amortized cost does not approximate market value, market prices as
determined above will be used.
 
   
    The value of other assets and securities for which quotations are not
readily available (including restricted and unlisted foreign securities) and
those securities for which it is inappropriate to determine the prices in
accordance with the above-stated procedures are determined in good faith at fair
value using methods determined by the Board of Directors. For purposes of
calculating net asset value per share, all assets and liabilities initially
expressed in foreign currencies will be translated into U.S. dollars at the mean
of the bid and asked price for such currencies against the U.S. dollar last
quoted by any major bank.
    
 
    Although the legal rights of Class A and Class B shares will be identical,
the different expenses borne by each class will result in different net asset
values and dividends for the class. Dividends will differ by approximately the
amount of the distribution expense accrual differential among the classes. The
net asset value of Class B shares will generally be lower than the net asset
value of the Class A shares as a result of the distribution expenses charged to
Class B shares.
 
                            PERFORMANCE INFORMATION
 
    The Fund may from time to time advertise the "total return" for each class
of a Portfolio. THESE FIGURES ARE BASED ON HISTORICAL EARNINGS AND ARE NOT
INTENDED TO INDICATE FUTURE PERFORMANCE.
 
    Each of the Portfolios may advertise "total return" which shows what an
investment in a class of a Portfolio would have earned over a specified period
of time (such as one, five or ten years) assuming that all distributions and
dividends by the Portfolio were reinvested in the same class on the reinvestment
dates during the period. Total return does not take into account any federal or
state income taxes that may be payable on dividends and
 
                                       43
<PAGE>
distributions or on redemption. The Fund may also include comparative
performance information in advertising or marketing the Portfolios' shares,
including data from Lipper Analytical Services, Inc., other industry
publications, business periodicals, rating services and market indices.
 
    The performance figures for Class B shares will generally be lower than
those for Class A shares because of the distribution fee charged to Class B
shares.
 
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
 
    All income dividends and capital gains distributions for a class of shares
will be automatically reinvested in additional shares at net asset value, except
that, upon written notice to the Fund or by checking off the appropriate box in
the Distribution Option Section on the Account Registration Form, a shareholder
may elect to receive income dividends and capital gains distributions in cash.
 
   
    Each Portfolio expects to distribute substantially all of its taxable net
investment income in the form of annual dividends. Net realized capital gains,
if any, after reduction for any available tax loss carryforwards will also be
distributed annually.
    
 
    Undistributed net investment income is included in a Portfolio's net assets
for the purpose of calculating net asset value per share. Therefore, on the
"ex-dividend" date, the net asset value per share excludes the dividend (i.e.,
is reduced by the per share amount of the dividend). Dividends paid shortly
after the purchase of shares by an investor, although in effect a return of
capital, are taxable to shareholders subject to income tax.
 
    Because of the distribution fee and any other expenses that may be
attributable to the Class B shares, the net income attributable to and the
dividends payable on Class B shares will be lower than the net income
attributable to and the dividends payable on Class A shares. As a result, the
net asset value per share of the classes of the Portfolios will differ at times.
Expenses of the Portfolios allocated to a particular class of shares will be
borne on a pro rata basis by each outstanding share of that class.
 
                                     TAXES
 
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
 
    No attempt has been made to present a detailed explanation of the federal,
state, or local income tax treatment of the Portfolios or their shareholders.
Accordingly, shareholders are urged to consult their tax advisers regarding
specific questions as to federal, state and local income taxes.
 
    Each Portfolio is treated as a separate entity for federal income tax
purposes and is not combined with the Fund's other portfolios. Each Portfolio
intends to qualify for the special tax treatment afforded regulated investment
companies under Subchapter M of the Code, so that the Portfolio will be relieved
of federal income tax on that part of its net investment income and net capital
gain that is distributed to shareholders.
 
   
    Each Portfolio intends to distribute substantially all of its taxable net
investment income (including, for this purpose, net short-term capital gain) to
shareholders. Dividends from a Portfolio's net investment income are taxable to
shareholders as ordinary income, whether received in cash or in additional
shares. Such dividends paid by a Portfolio will generally qualify for the 70%
dividends-received deduction for corporate shareholders
    
 
                                       44
<PAGE>
only to the extent of the aggregate qualifying dividend income received by the
Portfolio from U.S. corporations. Each Portfolio will report annually to its
shareholders the amount of dividend income qualifying for such treatment.
 
    Distributions of net capital gain (the excess of net long-term capital gain
over net short-term capital loss) are taxable to shareholders as long-term
capital gain, regardless of how long shareholders have held their shares. Each
Portfolio will send reports annually to its shareholders of the federal income
tax status of all distributions made during the preceding year.
 
    Each Portfolio intends to make sufficient distributions or deemed
distributions of its ordinary income and capital gain net income (the excess of
short-term and long-term capital gain over short-term and long-term capital
loss, including any available capital loss carryforwards) prior to the end of
each calendar year to avoid liability for federal excise tax.
 
    Dividends and other distributions declared by a Portfolio in October,
November or December of any year and payable to shareholders of record on a date
in such month will be deemed to have been paid by the Portfolio and received by
the shareholders in that year if the distributions are paid by the Portfolio at
any time during the following January.
 
   
    The Fund may be required to withhold and remit to the U.S. Treasury 31% of
any dividends, capital gains distributions and redemption proceeds paid to any
individual or certain other non-corporate shareholder (1) who has failed to
provide a correct taxpayer identification number (generally an individual's
social security number or non-individual's employer identification number) on
the Application Form, (2) who is subject to backup withholding by the Internal
Revenue Service, or (3) who has not certified to the Fund that such shareholder
is not subject to backup withholding. This backup withholding is not an
additional tax, and any amounts withheld may be credited against the
shareholder's ultimate U.S. tax liability.
    
 
    The sale, exchange or redemption of shares will result in taxable gain or
loss to the selling, exchanging or redeeming shareholder, depending upon whether
the fair market value of the sale, exchange or redemption proceeds exceed or are
less than the shareholder's adjusted basis in the sold, exchanged or redeemed
shares. If capital gain distributions have been made with respect to shares that
are sold at a loss after being held for six months or less, then the loss is
treated as a long-term capital loss to the extent of the capital gain
distributions.
 
    Conversion of shares between classes are not taxable events to the
shareholder.
 
    Shareholders are urged to consult with their tax advisors concerning the
application of state and local income taxes to investments in a Portfolio, which
may differ from the federal income tax consequences described above.
 
    Investment income received by a Portfolio from sources within foreign
countries may be subject to foreign income taxes withheld at the source. To the
extent that a Portfolio is liable for foreign income taxes so withheld, each
Portfolio intends to operate so as to meet the requirements of the Code to pass
through to the shareholders credit for foreign income taxes paid. Although each
Portfolio intends to meet Code requirements to pass through credit for such
taxes, there can be no assurance that each Portfolio will be able to do so.
 
                                       45
<PAGE>
    THE TAX DISCUSSION SET FORTH ABOVE IS INCLUDED FOR GENERAL INFORMATION ONLY.
PROSPECTIVE INVESTORS SHOULD CONSULT THEIR OWN TAX ADVISERS WITH RESPECT TO THE
TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN A PORTFOLIO.
 
                             PORTFOLIO TRANSACTIONS
 
    The Adviser selects the brokers or dealers that will execute the purchases
and sales of investment securities for each of the Fund's portfolios. The
Adviser seeks the best execution of all portfolio transactions. A portfolio may
pay higher commission rates than the lowest available when the Adviser believes
it is reasonable to do so in light of the value of the research, statistical,
and pricing services provided by the broker effecting the transaction.
 
    It is not the Fund's practice to allocate brokerage or principal business on
the basis of sales of shares which may be made through intermediary brokers or
dealers. However, the Adviser may, consistent with NASD rules, place portfolio
orders with qualified broker-dealers who recommend the applicable portfolio to
their clients or who act as agents in the purchase of shares of the portfolio
for their clients.
 
    Subject to the overriding objective of obtaining the best execution of
orders, the Fund may use broker-dealer affiliates of the Adviser, including
Morgan Stanley, to effect portfolio brokerage transactions under procedures
adopted by the Fund's Board of Directors. For such transactions, the commission
rates and other remuneration paid to Morgan Stanley or other affiliates must be
fair and reasonable in comparison to those of other broker-dealers for
comparable transactions involving similar securities being purchased or sold
during a comparable time period.
 
PORTFOLIO TURNOVER
 
   
    The Portfolios generally do not invest for short-term trading purposes,
however, when circumstances warrant, each Portfolio may sell investment
securities without regard to the length of time they have been held. Market
conditions in a given year could result in a higher or lower portfolio turnover
rate than expected and the Portfolios will not consider portfolio turnover rate
a limiting factor in making investment decisions consistent with their
respective objectives and policies. For the fiscal year ended December 31, 1996,
the Latin America Portfolio had a portfolio turnover rate of 192%. As portfolio
turnover increases, the Portfolios may expect to pay correspondingly increased
brokerage and trading costs. In addition to transaction costs, higher portfolio
turnover may result in the realization of capital gains. As discussed under
"Taxes," to the extent net short-term capital gains are realized, any
distributions resulting from such gains are considered ordinary income for
federal income tax purposes.
    
 
                              GENERAL INFORMATION
 
DESCRIPTION OF COMMON STOCK
 
   
    The Fund was organized as a Maryland corporation on June 16, 1988. The
Articles of Incorporation, as amended and restated, permit the Fund to issue up
to 35 billion shares of common stock, with $.001 par value per share. Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number of shares the Fund is authorized to issue without the approval of the
shareholders of the Fund. The Board of Directors has the power to designate one
or more classes of shares of common stock and to classify and reclassify
    
 
                                       46
<PAGE>
any unissued shares with respect to such classes. The shares of common stock of
each Portfolio are currently classified into two classes, the Class A shares and
the Class B shares, except for the International Small Cap, Money Market and
Municipal Money Market Portfolios, which offer only Class A shares.
 
    The shares of each Portfolio, when issued, will be fully paid,
nonassessable, fully transferable and redeemable at the option of the holder.
The shares have no preference as to conversion, exchange, dividends, retirement
or other features and have no pre-emptive rights. The shares of each Portfolio
have non-cumulative rights, which means that the holders of more than 50% of the
shares voting for the election of Directors can elect 100% of the Directors if
they choose to do so. Persons or organizations owning 25% or more of the
outstanding shares of a Portfolio may be presumed to "control" (as defined in
the 1940 Act) such Portfolio. Under Maryland law, the Fund is not required to
hold an annual meeting of its shareholders unless required to do so under the
1940 Act.
 
REPORTS TO SHAREHOLDERS
 
    The Fund will send to its shareholders annual and semi-annual reports; the
financial statements appearing in annual reports are audited by independent
accountants. Monthly unaudited portfolio data is also available from the Fund
upon request.
 
    In addition, the Adviser or its agent, as Transfer Agent, will send to each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
 
CUSTODIAN
 
    Chase is the Fund's custodian for domestic and certain foreign assets. Chase
is not an affiliate of the Adviser or the Distributor. Morgan Stanley Trust
Company, Brooklyn, New York ("MSTC"), an affiliate of the Adviser and the
Distributor, acts as the Fund's custodian for assets held outside the United
States and employs subcustodians approved by the Board of Directors of the Fund
in accordance with regulations of the Securities and Exchange Commission for the
purpose of providing custodial services for such assets. MSTC may also hold
certain domestic assets for the Fund. For more information on the custodians,
see "General Information -- Custody Arrangements" in the Statement of Additional
Information.
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
    Chase Global Funds Services Company, 73 Tremont Street, Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
 
INDEPENDENT ACCOUNTANTS
 
   
    Price Waterhouse LLP serves as independent accountants for the Fund and
audits its annual financial statements.
    
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       47
<PAGE>
   MORGAN STANLEY INSTITUTIONAL FUND, INC.
  GLOBAL EQUITY, INTERNATIONAL EQUITY, INTERNATIONAL SMALL CAP,
   ASIAN EQUITY, EUROPEAN EQUITY, JAPANESE EQUITY AND LATIN AMERICAN PORTFOLIOS
   P.O. BOX 2798, BOSTON, MA 02208-2798
 
                           ACCOUNT REGISTRATION FORM
 
<TABLE>
<C>   <S>                                            <C>
      ACCOUNT INFORMATION                            If you need assistance in filling out this form for the Morgan Stanley
      Fill in where applicable                       Institutional Fund, please contact your Morgan Stanley representative
                                                     or call us toll free 1-(800)-548-7786. Please print all items except
                                                     signature, and mail to the Fund at the address above.
  A)  REGISTRATION
      1. INDIVIDUAL
      2. JOINT TENANTS
         (RIGHTS OF SURVIVORSHIP PRESUMED UNLESS
         TENANCY IN COMMON
         IS INDICATED)
</TABLE>
 
1.
         First Name    Initial         Last Name
2.
         First Name    Initial         Last Name
         First Name    Initial         Last Name
 
<TABLE>
<C>   <S>                                            <C>
      3. CORPORATIONS,
         TRUSTS AND OTHERS
         Please call the Fund for additional
      documents that may be required to set up
      account and to authorize transactions.
</TABLE>
 
3.
 
<TABLE>
<S>                     <C>                 <C>                   <C>               <C>
Type of Registration:   / / INCORPORATED    / / UNINCORPORATED    / / PARTNERSHIP   / / UNIFORM GIFT/TRANSFER TO MINOR
                                            ASSOCIATION                               (ONLY ONE CUSTODIAN AND MINOR PERMITTED)
</TABLE>
 
/ / TRUST ________________________  / / OTHER (Specify) ________________________
 
<TABLE>
<C>   <S>                                            <C>
  B)  MAILING ADDRESS
      Please fill in completely, including
      telephone number(s).
</TABLE>
 
/ / United States Citizen  / / Resident Alien
                   Street or P.O. Box
                   City
                   State                   Zip
Home Telephone No.                   Business Telephone No.
/ / Non-Resident Alien:
Permanent Address (Where you reside permanently for tax purposes)
                   Street Address
                   City
                   Country                   Postal Code
Home Telephone No.                    Business Telephone No.
 
Current Mailing Address (If different from Permanent Address)
                   Street Address
                   City
                   Country
Postal Code
Home Telephone No.                   Business Telephone No.
 
<TABLE>
<C>   <S>                                            <C>                                  <C>
  C)  TAXPAYER                                       Enter your Taxpayer Identification Number. For most individual
      IDENTIFICATION                                 taxpayers, this is your Social Security Number.
      NUMBER
      1. INDIVIDUAL
      2.   JOINT TENANTS
           (RIGHTS OF SURVIVORSHIP PRESUMED UNLESS
           TENANCY IN COMMON
           IS INDICATED)
      For Custodian account
      of a minor (Uniform
      Gifts/Transfers to Minor
      Acts), give the Social
      Security Number of
      the minor
                                                                                          OR
                                                     1.         TAXPAYER IDENTIFICATION                      SOCIAL SECURITY
                                                     NUMBER ("TIN")                                NUMBER ("SSN")
                                                                                              OR
                                                     2.                             TIN
                                                                                                                             SSN
                                                                                              OR
                                                     TIN
                                                                                                                             SSN
                                                     IMPORTANT TAX INFORMATION
                                                     You (as a payee) are required by law to provide us (as payer) with your
                                                     correct TIN(s) or SSN(s). Accounts that have a missing or incorrect
                                                     TIN(s) or SSN(s) will be subject to backup withholding at a 31% rate on
                                                     dividends, distributions and other payments. If you have not provided us
                                                     with your correct TIN(s) or SSN(s), you may be subject to a $50 penalty
                                                     imposed by the Internal Revenue Service.
                                                     Backup withholding is not an additional tax; the tax liability of
                                                     persons subject to backup withholding will be reduced by the amount of
                                                     tax withheld. If withholding results in an overpayment of taxes, a
                                                     refund may be obtained.
                                                     You may be notified that you are subject to backup withholding under
                                                     Section 3406(a)(1)(C) of the Internal Revenue Code because you have
                                                     underreported interest or dividends or you were required to, but failed
                                                     to, file a return which would have included a reportable interest or
                                                     dividend payment.
</TABLE>
 
<PAGE>
 
   
<TABLE>
<C>   <S>                                  <C>                             <C>                   <C>
  D)  PORTFOLIO AND                        For Purchase of the following   / / Class A Shares $  / / Class B Shares $
      CLASS SECTION                        Portfolio(s):                   / / Class A Shares $
      (Class A shares minimum $500,000     Global Equity Portfolio         / / Class A Shares $  / / Class B Shares $
      for each Portfolio and Class B       International Equity Portfolio  / / Class A Shares $  / / Class B Shares $
      shares minimum $100,000 for the      International Small Cap         / / Class A Shares $  / / Class B Shares $
      Global Equity, International         Portfolio                       / / Class A Shares $  / / Class B Shares $
      Equity, Asian Equity, European       Asian Equity Portfolio          / / Class A Shares $  / / Class B Shares $
      Equity, Japanese Equity and Latin    European Equity Portfolio
      American Equity Portfolios). Please  Japanese Equity Portfolio
      indicate Portfolio, class and        Latin American Portfolio
      amount.
                                                                           Total Initial Investment $
</TABLE>
    
 
<TABLE>
<C>   <S>                        <C>
  E)  METHOD OF
      INVESTMENT
      Please indicate
      portfolio, manner of
      payment.
</TABLE>
 
Payment by:
 
/ / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND,
INC.--PORTFOLIO NAME)
 
<TABLE>
<S>                                                                          <C>
/ / Exchange $ From                                                                     -- - - - - - - - - - -- - -
                            Name of Portfolio                                                   Account No.
/ / Account previously established by:  / / Phone exchange  / / Wire on                 -- - - - - - - - - - -- - -
                                                                                      Account No.               (Check
                                                                                (Previously assigned by the Fund)     Digit)
                                                                                                                          Date
</TABLE>
 
<TABLE>
<C>   <S>                        <C>
  F)  DISTRIBUTION               Income dividends and capital gains distributions (if any) to
      OPTION                     be reinvested in additional shares unless either box below
                                 is checked.
                                 / / Income dividends to be paid in cash, capital gains
                                 distributions (if any) in shares.
                                 / / Income dividends and capital gains distributions (if
                                 any) to be paid in cash.
</TABLE>
 
<TABLE>
<C>   <S>                             <C>                                       <C>
  G)  TELEPHONE                       / / I/we hereby authorize the Fund and
      REDEMPTION                      its agents to honor any telephone         Name of COMMERCIAL Bank (Not Savings
      AND EXCHANGE                    requests to wire redemption proceeds to   Bank)
      OPTION                          the commercial bank indicated at right    Bank Account No.
      Please select at time of        and/or mail redemption proceeds to the
      initial application if you      name and address in which my/our fund
      wish to redeem or exchange      account is registered if such requests                                        Bank
      shares by telephone. A          are believed to be authentic.                                                  ABA
      SIGNATURE GUARANTEE IS          The Fund and the Fund's Transfer Agent                                         No.
      REQUIRED IF BANK ACCOUNT IS     will employ reasonable procedures to
      NOT REGISTERED IDENTICALLY TO   confirm that instructions communicated    Name(s) in which your BANK Account is
      YOUR FUND ACCOUNT.              by telephone are genuine. These           Established
      TELEPHONE REQUESTS FOR          procedures include requiring the
      REDEMPTIONS OR EXCHANGE WILL    investor to provide certain personal      Bank's Street
      NOT BE HONORED UNLESS THE BOX   identification information at the time    Address
      IS CHECKED.                     an account is opened and prior to
                                      effecting each transaction requested by   City  State  Zip
                                      telephone. In addition, all telephone
                                      transaction requests will be recorded
                                      and investors may be required to provide
                                      additional telecopied written
                                      instructions of transaction requests.
                                      Neither the Fund nor the Transfer Agent
                                      will be responsible for any loss,
                                      liability, cost or expense for following
                                      instructions received by telephone that
                                      it reasonably believes to be genuine.
</TABLE>
 
   
<TABLE>
<C>   <S>                                  <C>
  H)  INTERESTED PARTY
      OPTION                                                                                                Name
      In addition to the account
      statement sent to my/our registered
      address, I/we hereby authorize the                                                                   Address
      Fund to mail duplicate statements
      to the name and address provided at  City         State         Zip Code
      right.
</TABLE>
    
 
<TABLE>
<C>   <S>                                  <C>
  I)  DEALER
      INFORMATION
                                           Representative Name              Representative No.             Branch
                                           No.
</TABLE>
 
<PAGE>
 
<TABLE>
<C>   <S>                                  <C>
  J)  SIGNATURE OF
      ALL HOLDERS
      AND TAXPAYER
      CERTIFICATION
      Sign Here ,
</TABLE>
 
<TABLE>
<S>                                  <C>
The undersigned certify that I/we have full authority and legal capacity
to purchase and redeem shares of the Fund and affirm that I/we have
received a current Prospectus of the Morgan Stanley Institutional Fund,
Inc. and agree to be bound by its terms.
  BY SIGNING THIS APPLICATION, I/WE HEREBY CERTIFY UNDER PENALTIES OF
PERJURY THAT THE INFORMATION ON THIS APPLICATION IS COMPLETE AND CORRECT
AND THAT AS REQUIRED BY FEDERAL LAW (PLEASE CHECK APPLICABLE BOXES
BELOW):
 
/ / U.S. CITIZEN(S)/TAXPAYER(S):
 
      / / I/WE CERTIFY THAT (1) THE NUMBER(S) SHOWN ABOVE ON THIS FORM
          IS/ARE THE CORRECT SSN(S) OR TIN(S) AND (2) I/WE ARE NOT
          SUBJECT TO ANY BACKUP WITHHOLDING EITHER BECAUSE (A) I/WE ARE
          EXEMPT FROM BACKUP WITHHOLDING; (B) I/WE HAVE NOT BEEN
          NOTIFIED BY THE INTERNAL REVENUE SERVICE ("IRS") THAT I/WE ARE
          SUBJECT TO BACKUP WITHHOLDING AS A RESULT OF A FAILURE TO
          REPORT ALL INTEREST OR DIVIDENDS; OR (C) THE IRS HAS NOTIFIED
          ME/US THAT I AM/WE ARE NO LONGER SUBJECT TO BACKUP
          WITHHOLDING.
 
      / / IF NO TIN(S) OR SSN(S) HAS/HAVE BEEN PROVIDED ABOVE, I/WE HAVE
          APPLIED, OR INTEND TO APPLY, TO THE IRS OR THE SOCIAL SECURITY
          ADMINISTRATION FOR A TIN OR A SSN AND I/WE UNDERSTAND THAT IF
          I/ WE DO NOT PROVIDE EITHER NUMBER TO CHASE GLOBAL FUNDS
          SERVICES COMPANY ("CGFSC") WITHIN 60 DAYS OF THE DATE OF THIS
          APPLICATION OR IF I/WE FAIL TO FURNISH MY/OUR CORRECT SSN(S)
          OR TIN(S), I/WE MAY BE SUBJECT TO A PENALTY AND A 31% BACKUP
          WITHHOLDING ON DISTRIBUTIONS AND REDEMPTION PROCEEDS. (PLEASE
          PROVIDE EITHER NUMBER ON IRS FORM W-9). YOU MAY REQUEST SUCH
          FORM BY CALLING CGFSC AT 800-282-4404.
 
/ / NON-U.S. CITIZEN(S)/TAXPAYER(S)
  UNDER PENALTIES OF PERJURY, I/WE CERTIFY THAT I/WE ARE NOT U.S.
CITIZENS OR RESIDENTS AND I/WE ARE EXEMPT FOREIGN PERSONS AS DEFINED BY
THE INTERNAL REVENUE SERVICE.
 
THE INTERNAL REVENUE SERVICE DOES NOT REQUIRE YOUR CONSENT TO ANY
PROVISION OF THIS DOCUMENT OTHER THAN THE CERTIFICATIONS REQUIRED TO
AVOID BACKUP WITHHOLDING.
 
                                     (X)
(X)                                  Signature (if joint account, both
Signature            Date            must sign)      Date
</TABLE>
<PAGE>
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
 
  NO DEALER, SALES REPRESENTATIVE OR ANY OTHER PERSON HAS BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS HAVING BEEN AUTHORIZED BY THE FUND OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION TO
ANY PERSON TO WHOM IT IS UNLAWFUL TO MAKE SUCH OFFER OR SOLICITATION IN SUCH
JURISDICTION.
 
                           --------------------------
 
                               TABLE OF CONTENTS
 
   
<TABLE>
<CAPTION>
                                                    PAGE
                                                    ----
<S>                                                 <C>
Fund Expenses.....................................    2
Financial Highlights..............................    6
Prospectus Summary................................   14
Investment Objectives and Policies................   18
Additional Investment Information.................   24
Investment Limitations............................   31
Management of the Fund............................   32
Purchase of Shares................................   35
Redemption of Shares..............................   40
Shareholder Services..............................   42
Valuation of Shares...............................   42
Performance Information...........................   43
Dividends and Capital Gains Distributions.........   44
Taxes.............................................   44
Portfolio Transactions............................   46
General Information...............................   46
Account Registration Form
</TABLE>
    
 
                            GLOBAL EQUITY PORTFOLIO
                         INTERNATIONAL EQUITY PORTFOLIO
                       INTERNATIONAL SMALL CAP PORTFOLIO
                             ASIAN EQUITY PORTFOLIO
                           EUROPEAN EQUITY PORTFOLIO
                           JAPANESE EQUITY PORTFOLIO
                            LATIN AMERICAN PORTFOLIO
 
                               PORTFOLIOS OF THE
 
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
 
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
 
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                      P.O. BOX 2798, BOSTON, MA 02208-2798
 
- ---------------------------------------
- ---------------------------------------
- ---------------------------------------
- ---------------------------------------
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
     ----------------------------------------------------------------------
 
                           EMERGING MARKETS PORTFOLIO
                        EMERGING MARKETS DEBT PORTFOLIO
 
                               PORTFOLIOS OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
 
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
 
                                ----------------
 
   
    Morgan  Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company, or mutual fund, which offers redeemable shares in
a   series   of   diversified   and   non-diversified   investment    portfolios
("portfolios").  The  Fund  is  designed  to  provide  clients  with  attractive
alternatives for meeting their investment needs. The Fund currently consists  of
twenty-nine  portfolios representing a  broad range of  investment choices. This
prospectus (the "Prospectus") pertains to the Class A and the Class B shares  of
the  Emerging Markets Portfolio and the Emerging Markets Debt Portfolio (each, a
"Portfolio" and collectively, the "Portfolios"). The Class A and Class B  shares
currently   offered  by   the  Portfolios  have   different  minimum  investment
requirements and fund  expenses. Shares of  the portfolios are  offered with  no
sales  charge, exchange  fee or redemption  fee, (except  that the International
Small Cap Portfolio may impose a transaction fee).
    
 
    THE EMERGING MARKETS PORTFOLIO  MAY INVEST IN  EQUITY SECURITIES OF  RUSSIAN
COMPANIES.  RUSSIA'S SYSTEM OF  SHARE REGISTRATION AND  CUSTODY INVOLVES CERTAIN
RISKS OF  LOSS  THAT ARE  NOT  NORMALLY  ASSOCIATED WITH  INVESTMENTS  IN  OTHER
SECURITIES MARKETS. SEE "ADDITIONAL INVESTMENT INFORMATION -- RUSSIAN SECURITIES
TRANSACTIONS."
 
    The  Fund is designed  to meet the investment  needs of discerning investors
who place a premium on quality  and personal service. With Morgan Stanley  Asset
Management   Inc.  as   Adviser  and   Administrator  (the   "Adviser"  and  the
"Administrator") and with Morgan Stanley  & Co. Incorporated ("Morgan  Stanley")
as  Distributor, the  Fund makes available  to institutional and  high net worth
individual investors a series  of portfolios which  benefit from the  investment
expertise  and commitment to  excellence associated with  Morgan Stanley and its
affiliates.
 
    This Prospectus is designed to set forth concisely the information about the
Fund that a prospective investor should  know before investing and it should  be
retained  for future reference. The Fund  offers additional portfolios which are
described in other prospectuses  and under the  "Prospectus Summary" below.  The
Fund  currently offers  the following  portfolios: (i)  GLOBAL AND INTERNATIONAL
EQUITY -- Active  Country Allocation, Asian  Equity, Emerging Markets,  European
Equity,  Global  Equity, Gold,  International  Equity, International  Small Cap,
Japanese Equity and Latin  American Portfolios; (ii)  U.S. EQUITY --  Aggressive
Equity, Emerging Growth, Equity Growth, Small Cap Value Equity, Technology, U.S.
Real  Estate and Value Equity Portfolios;  (iii) BALANCED -- Balanced Portfolio;
(iv) FIXED INCOME -- Emerging Markets  Debt, Fixed Income, Global Fixed  Income,
High  Yield and Municipal Bond Portfolios; and  (v) MONEY MARKET -- Money Market
and Municipal Money Market Portfolios. Additional information about the Fund  is
contained  in a "Statement of Additional  Information," dated May 1, 1997, which
is incorporated herein by reference. The Statement of Additional Information and
the prospectuses pertaining to  the other portfolios of  the Fund are  available
upon  request and without charge  by writing or calling  the Fund at the address
and telephone number set forth above.
 
 THESE SECURITIES HAVE NOT  BEEN APPROVED OR  DISAPPROVED BY THE  SECURITIES
    AND   EXCHANGE  COMMISSION,  NOR  HAS  THE  SECURITIES  AND  EXCHANGE
       COMMISSION PASSED  UPON  THE  ACCURACY  OR  ADEQUACY  OF  THIS
           PROSPECTUS.  ANY  REPRESENTATION TO  THE CONTRARY  IS A
                                         CRIMINAL OFFENSE.
 
                   THE DATE OF THIS PROSPECTUS IS MAY 1, 1997
<PAGE>
                                 FUND EXPENSES
 
    The  following table illustrates the expenses and fees that a shareholder of
the Portfolios indicated below will incur:
   
<TABLE>
<CAPTION>
                                                                                              EMERGING
                                                                                 EMERGING      MARKETS
                                                                                  MARKETS       DEBT
SHAREHOLDER TRANSACTION EXPENSES                                                 PORTFOLIO    PORTFOLIO
- ------------------------------------------------------------------------------  -----------  -----------
<S>                                                                             <C>          <C>
Maximum Sales Load Imposed on Purchases
  Class A.....................................................................        None         None
  Class B.....................................................................        None         None
Maximum Sales Load Imposed on Reinvested Dividends
  Class A.....................................................................        None         None
  Class B.....................................................................        None         None
Deferred Sales Load
  Class A.....................................................................        None         None
  Class B.....................................................................        None         None
Redemption Fees
  Class A.....................................................................        None         None
  Class B.....................................................................        None         None
Exchange Fees
  Class A.....................................................................        None         None
  Class B.....................................................................        None         None
 
<CAPTION>
 
ANNUAL FUND OPERATING EXPENSES
- ------------------------------------------------------------------------------
 (AS A PERCENTAGE OF AVERAGE NET ASSETS)
<S>                                                                             <C>          <C>
Management Fee*
  Class A.....................................................................       1.25%        1.00%
  Class B.....................................................................       1.25%        1.00%
12b-1 Fees
  Class A.....................................................................        None         None
  Class B.....................................................................       0.25%        0.25%
Other Expenses
  Class A.....................................................................       0.49%        0.42%
  Class B.....................................................................       0.49%        0.40%
                                                                                -----------  -----------
Total Operating Expenses*
  Class A.....................................................................       1.74%        1.42%
  Class B.....................................................................       1.99%        1.65%
                                                                                -----------  -----------
                                                                                -----------  -----------
</TABLE>
    
 
- ------------------------------
   
*The Adviser  has agreed  to  waive its  management  fees and/or  reimburse  the
 Portfolios, if necessary, if such fees would cause the Portfolios' total annual
 operating  expenses, as  a percentage  of average  daily net  assets, to exceed
 1.75% for the Class A shares and  2.00% for the Class B shares. The  management
 fees  are 1.25% for the  Emerging Markets Portfolio and  1.00% for the Emerging
 Markets Debt Portfolio. The Adviser reserves the right to terminate any of  its
 fee  waivers and/or expense reimbursements at  any time in its sole discretion.
 The Adviser  reserves the  right to  terminate any  of its  fee waivers  and/or
 expense  reimbursements  at  any  time  in  its  sole  discretion.  For further
 information on Fund expenses, see "Management of the Fund."
    
 
                                       2
<PAGE>
    The purpose of the  table above is to  assist the investor in  understanding
the  various expenses that an  investor in the Portfolios  will bear directly or
indirectly. Expenses and fees for the Portfolios are based on actual figures for
the fiscal year ended December  31, 1996. Due to  the continuous nature of  Rule
12b-1  fees, long term Class B shareholders  may pay more than the equivalent of
the  maximum  front-end  sales  charges  otherwise  permitted  by  the  National
Association of Securities Dealers, Inc. ("NASD") Conduct Rules.
 
    The  following  example illustrates  the expenses  that you  would pay  on a
$1,000 investment assuming (1) a 5% annual rate of return and (2) redemption  at
the  end of each time period. As noted in the table above, the Portfolios charge
no redemption  fees  of  any kind.  The  following  example is  based  on  total
operating expenses of the Portfolios after fee waivers.
 
   
<TABLE>
<CAPTION>
                                                                       1 YEAR       3 YEARS      5 YEARS     10 YEARS
                                                                     -----------  -----------  -----------  -----------
<S>                                                                  <C>          <C>          <C>          <C>
Emerging Markets Portfolio
  Class A..........................................................   $      18    $      55    $      94    $     205
  Class B..........................................................          20           62          107          232
Emerging Markets Debt Portfolio
  Class A..........................................................          27           84          143          303
  Class B..........................................................          28           87          148          314
</TABLE>
    
 
    THIS  EXAMPLE SHOULD  NOT BE CONSIDERED  A REPRESENTATION OF  PAST OR FUTURE
EXPENSES OR  PERFORMANCE. ACTUAL  EXPENSES MAY  BE GREATER  OR LESS  THAN  THOSE
SHOWN.
 
                                       3
<PAGE>
                              FINANCIAL HIGHLIGHTS
 
   
    The  following tables provide financial highlights for the Class A and Class
B shares for the Emerging Markets and Emerging Markets Debt Portfolios for  each
of  the periods presented. The audited  financial highlights for the Portfolios'
shares for  each of  the periods  presented  are part  of the  Fund's  financial
statements  which  appear  in the  Fund's  December  31, 1996  Annual  Report to
Shareholders and which are incorporated by reference in the Fund's Statement  of
Additional  Information. The  Portfolios' financial  highlights for  each of the
periods presented have been audited  by Price Waterhouse LLP, whose  unqualified
report  thereon is also incorporated by reference in the Statement of Additional
Information. Additional  performance  information  is  included  in  the  Annual
Report.  The Annual Report and the  financial statements therein, along with the
Statement of Additional Information, are available  at no cost from the Fund  at
the  address and telephone  number noted on  the cover page  of this Prospectus.
After October 31, 1992, the Fund changed its fiscal year end to December 31. The
following  information  should  be  read  in  conjunction  with  the   financial
statements and notes thereto.
    
 
                                       4
<PAGE>
                           EMERGING MARKETS PORTFOLIO
   
<TABLE>
<CAPTION>
                                                                                      CLASS A
                                                       ---------------------------------------------------------------------
                                                                                                                    PERIOD
                                                                                                          TWO        FROM
                                                         YEAR        YEAR        YEAR        YEAR       MONTHS     SEPTEMBER
                                                         ENDED       ENDED       ENDED       ENDED       ENDED     25, 1992*
                                                       DECEMBER    DECEMBER    DECEMBER    DECEMBER    DECEMBER       TO
                                                          31,         31,         31,         31,         31,       OCTOBER
                                                         1996        1995        1994        1993        1992      31, 1992
                                                       ---------   ---------   ---------   ---------   ---------   ---------
<S>                                                    <C>         <C>         <C>         <C>         <C>         <C>
NET ASSET VALUE, BEGINNING OF PERIOD.................  $ 13.14     $ 16.30     $ 19.00     $ 10.22     $ 10.11     $ 10.00
                                                       ---------   ---------   ---------   ---------   ---------   ---------
                                                       ---------   ---------   ---------   ---------   ---------   ---------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (Loss) (1)...................     0.09        0.08       (0.04)      (0.01)         --          --
  Net Realized and Unrealized Gain (Loss) on
   Investments.......................................     1.51       (2.05)      (1.69)       8.79        0.11        0.11
                                                       ---------   ---------   ---------   ---------   ---------   ---------
    Total from Investment Operations.................     1.60       (1.97)      (1.73)       8.78        0.11        0.11
                                                       ---------   ---------   ---------   ---------   ---------   ---------
DISTRIBUTIONS
  Net Investment Income..............................    (0.08)      (0.06)         --          --          --          --
  Net Realized Gain..................................       --       (1.13)      (0.97)         --          --          --
                                                       ---------   ---------   ---------   ---------   ---------   ---------
    Total Distributions..............................    (0.08)      (1.19)      (0.97)         --          --          --
                                                       ---------   ---------   ---------   ---------   ---------   ---------
NET ASSET VALUE, END OF PERIOD.......................  $ 14.66     $ 13.14     $ 16.30     $ 19.00     $ 10.22     $ 10.11
                                                       ---------   ---------   ---------   ---------   ---------   ---------
TOTAL RETURN.........................................    12.19%     (12.77)%     (9.63)%     85.91%       1.09%       1.10%
                                                       ---------   ---------   ---------   ---------   ---------   ---------
                                                       ---------   ---------   ---------   ---------   ---------   ---------
RATIOS AND SUPPLEMENTAL DATA:
  Net Assets, End of Period (Thousands)..............  $1,304,006  $876,591    $929,638    $735,352    $74,219     $28,806
  Ratio of Expenses to Average Net Assets (1)........     1.74%       1.72%       1.75%       1.75%       1.75%**     1.75%**
  Ratio of Net Investment Income (Loss) to Average
   Net Assets (1)....................................     0.69%       0.60%      (0.26)%     (0.06)%     (0.33)%**   (0.53)%**
  Portfolio Turnover Rate............................       55%         54%         32%         52%          2%          0%
  Average Commission Rate#...........................  $0.0006         N/A         N/A         N/A         N/A         N/A
 
<CAPTION>
                                                        CLASS B
                                                       ---------
                                                        PERIOD
                                                         FROM
                                                        JANUARY
                                                          2,
                                                        1996***
                                                          TO
                                                       DECEMBER
                                                       31, 1996
                                                       ---------
<S>                                                    <C>
NET ASSET VALUE, BEGINNING OF PERIOD.................  $ 13.25
                                                       ---------
                                                       ---------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (Loss) (1)...................     0.04
  Net Realized and Unrealized Gain (Loss) on
   Investments.......................................     1.42
                                                       ---------
    Total from Investment Operations.................     1.46
                                                       ---------
DISTRIBUTIONS
  Net Investment Income..............................    (0.05)
  Net Realized Gain..................................       --
                                                       ---------
    Total Distributions..............................    (0.05)
                                                       ---------
NET ASSET VALUE, END OF PERIOD.......................  $ 14.66
                                                       ---------
TOTAL RETURN.........................................    11.04%
                                                       ---------
                                                       ---------
RATIOS AND SUPPLEMENTAL DATA:
  Net Assets, End of Period (Thousands)..............  $14,213
  Ratio of Expenses to Average Net Assets (1)........     1.99%**
  Ratio of Net Investment Income (Loss) to Average
   Net Assets (1)....................................     0.33%**
  Portfolio Turnover Rate............................       55%
  Average Commission Rate#...........................  $0.0006
</TABLE>
    
 
- --------------------
   
<TABLE>
<C><S>                                                    <C>         <C>         <C>         <C>         <C>         <C>
(1) Effect of voluntary expense limitation during the
    period:
     Per share benefit to net investment income.........       N/A        N/A         N/A       $0.01      $0.00       $0.02
   Ratios before expense limitation:
     Expenses to Average Net Assets.....................       N/A        N/A         N/A        1.79  %    2.48   %**   4.82  %**
     Net Investment Loss to Average Net Assets..........       N/A        N/A         N/A       (0.10  )%  (1.06   )%**  (3.60  )%**
 
<CAPTION>
(1)
        N/A
 
        N/A
        N/A
 
<CAPTION>
 
</TABLE>
    
 
   
  * Commencement of Operations.
    
 
   
 ** Annualized
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
   
 # Beginning with fiscal year 1996, the Portfolio is required to disclose the
   average commission rate per share it paid for portfolio trades, on which
   commissions were charged, during the period. For the year ended December 31,
   1996, the average commission rate paid on trades on which commissions were
   charged was 0.42% of the trade amount.
    
 
                                       5
<PAGE>
                        EMERGING MARKETS DEBT PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                                                       CLASS B
                                                                            CLASS A                   ---------
                                                            ---------------------------------------    PERIOD
                                                                                           PERIOD       FROM
                                                                                            FROM       JANUARY
                                                                                          FEBRUARY       2,
                                                                                             1,        1996***
                                                             YEAR ENDED     YEAR ENDED    1994* TO       TO
                                                            DECEMBER 31,   DECEMBER 31,   DECEMBER    DECEMBER
                                                                1996           1995       31, 1994    31, 1996
                                                            -------------  -------------  ---------   ---------
<S>                                                         <C>            <C>            <C>         <C>
NET ASSET VALUE, BEGINNING OF PERIOD......................   $      8.59    $      8.59   $ 10.00     $  8.68
                                                            -------------  -------------  ---------   ---------
                                                            -------------  -------------  ---------   ---------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income...................................          1.54           1.36      0.50        1.01
  Net Realized and Unrealized Gain (Loss) on
   Investments............................................          2.79           0.91    (1.91)        3.20
                                                            -------------  -------------  ---------   ---------
    Total from Investment Operations......................          4.33           2.27    (1.41)        4.21
                                                            -------------  -------------  ---------   ---------
DISTRIBUTIONS
  Net Investment Income...................................         (1.17)         (1.86)       --      (1.15)
  In Excess of Net Investment Income......................         (0.01)            --        --      (0.01)
  Net Realized Gain.......................................         (4.20)         (0.41)       --      (4.20)
                                                            -------------  -------------  ---------   ---------
    Total Distributions...................................         (5.38)         (2.27)       --      (5.36)
                                                            -------------  -------------  ---------   ---------
NET ASSET VALUE, END OF PERIOD............................   $      7.54    $      8.59   $  8.59     $  7.53
                                                            -------------  -------------  ---------   ---------
                                                            -------------  -------------  ---------   ---------
TOTAL RETURN..............................................         50.52%         28.23%  (14.10)%      48.52%
                                                            -------------  -------------  ---------   ---------
                                                            -------------  -------------  ---------   ---------
RATIO AND SUPPLEMENTAL DATA:
  Net Assets, End of Period (Thousands)...................      $152,142       $181,878   $144,949     $4,253
  Ratio of Expenses to Average Net Assets.................          2.70%          1.75%     1.49%**     2.81%**
  Ratio of Expenses to Average Net Assets (Excluding
   Dividend and Interest Expense).........................          1.42%           N/A       N/A        1.65%**
  Ratio of Net Investment Income to Average Net Assets....         11.66%         14.70%     9.97%**    11.09%**
  Portfolio Turnover Rate.................................           560%           406%      273%        560%
</TABLE>
    
 
- --------------
   
  * Commencement of operations.
    
 
   
 ** Annualized
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
                                       6
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
 
    The   Fund  consists  of   twenty-nine  portfolios,  offering  institutional
investors and high net  worth individual investors a  broad range of  investment
choices coupled with the advantages of a no-load mutual fund with Morgan Stanley
and  its affiliates providing customized  services as Adviser, Administrator and
Distributor.  Each  portfolio  offers  Class  A  shares  and,  except  for   the
International  Small Cap,  Money Market  and Municipal  Money Market Portfolios,
also offers Class B shares. Each portfolio has its own investment objective  and
policies  designed to meet its specific  goals. The investment objective of each
Portfolio described in this Prospectus is as follows:
 
    -The EMERGING  MARKETS PORTFOLIO  seeks  long-term capital  appreciation  by
     investing primarily in equity securities of emerging country issuers.
 
    -The  EMERGING MARKETS DEBT  PORTFOLIO seeks high  total return by investing
     primarily  in  debt  securities   of  government,  government-related   and
     corporate issuers located in emerging countries.
 
    The  other portfolios of the Fund  are described in other prospectuses which
may be obtained from the Fund at  the address and telephone number noted on  the
cover  page  of  this  Prospectus.  The  investment  objectives  of  these other
portfolios are listed below:
 
    GLOBAL AND INTERNATIONAL EQUITY:
 
    -The  ACTIVE   COUNTRY   ALLOCATION  PORTFOLIO   seeks   long-term   capital
     appreciation  by investing in accordance with country weightings determined
     by the  Adviser in  equity securities  of non-U.S.  issuers which,  in  the
     aggregate, replicate broad country indices.
 
    -The   ASIAN  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing primarily in equity securities of Asian issuers.
 
    -The CHINA GROWTH PORTFOLIO seeks to provide long-term capital  appreciation
     by  investing primarily  in equity  securities of  issuers in  The People's
     Republic of China, Hong Kong and Taiwan.
 
    -The EUROPEAN  EQUITY  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing primarily in equity securities of European issuers.
 
    -The  GLOBAL  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing primarily in equity securities  of issuers throughout the  world,
     including U.S. issuers.
 
    -The  GOLD  PORTFOLIO  seeks  long-term  capital  appreciation  by investing
     primarily in equity securities of  foreign and domestic issuers engaged  in
     gold-related activities.
 
    -The  INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation by
     investing primarily in equity securities of non-U.S. issuers.
 
    -The INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation  by
     investing  primarily in equity securities  of non-U.S. issuers domiciled in
     EAFE countries.
 
    -The INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital  appreciation
     by investing primarily in equity securities of non-U.S. issuers with equity
     market capitalizations of less than $1 billion.
 
                                       7
<PAGE>
    -The  JAPANESE  EQUITY  PORTFOLIO seeks  long-term  capital  appreciation by
     investing primarily in equity securities of Japanese issuers.
 
   
    -The LATIN  AMERICAN  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing  primarily in  equity securities  of Latin  American issuers and,
     from time to time, debt securities  issued or guaranteed by Latin  American
     governments or governmental entities.
    
 
    U.S. EQUITY:
 
    -The  AGGRESSIVE EQUITY  PORTFOLIO seeks  capital appreciation  by investing
     primarily in corporate equity and equity-linked securities.
 
    -The EMERGING  GROWTH  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing  primarily  in  growth-oriented equity  securities  of  small- to
     medium-sized corporations.
 
    -The  EQUITY  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing   in  growth-oriented  equity  securities  of  medium  and  large
     capitalization companies.
 
    -The MICROCAP PORTFOLIO  seeks long-term capital  appreciation by  investing
     primarily in growth-oriented equity securities of small corporations.
 
    -The  SMALL CAP VALUE EQUITY PORTFOLIO  seeks high long-term total return by
     investing in  undervalued  equity  securities  of  small-  to  medium-sized
     companies.
 
    -The  TECHNOLOGY PORTFOLIO seeks long-term capital appreciation by investing
     primarily in equity  securities of companies  that, in the  opinion of  the
     Portfolio's   investment  adviser,  are  expected  to  benefit  from  their
     involvement in technology and technology-related industries.
 
    -The U.S.  REAL ESTATE  PORTFOLIO  seeks to  provide above  average  current
     income  and long-term capital appreciation by investing primarily in equity
     securities of companies in  the U.S. real  estate industry, including  real
     estate investment trusts.
 
    -The  VALUE EQUITY PORTFOLIO seeks high  total return by investing in equity
     securities which the  Adviser believes  to be undervalued  relative to  the
     stock market in general at the time of purchase.
 
    BALANCED:
 
    -The  BALANCED PORTFOLIO seeks high total return while preserving capital by
     investing in  a  combination of  undervalued  equity securities  and  fixed
     income securities.
 
    FIXED INCOME:
 
    -The  FIXED INCOME PORTFOLIO seeks to produce a high total return consistent
     with the preservation of capital by investing in a diversified portfolio of
     fixed income securities.
 
    -The GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real  rate
     of  return while preserving capital by investing in fixed income securities
     of issuers throughout the world, including U.S. issuers.
 
    -The HIGH YIELD PORTFOLIO seeks to  maximize total return by investing in  a
     diversified  portfolio of high  yield fixed income  securities that offer a
     yield above  that  generally available  on  debt securities  in  the  three
     highest rating categories of the recognized rating services.
 
                                       8
<PAGE>
    -The  MORTGAGE-BACKED SECURITIES PORTFOLIO seeks to  produce as high a level
     of current income  as is  consistent with  the preservation  of capital  by
     investing  primarily  in  a  variety  of  investment-grade  mortgage-backed
     securities.
 
    -The MUNICIPAL  BOND PORTFOLIO  seeks to  produce a  high level  of  current
     income  consistent with preservation of principal by investing primarily in
     municipal obligations, the interest on which is exempt from federal  income
     tax.
 
    MONEY MARKET:
 
    -The  MONEY MARKET PORTFOLIO  seeks to maximize  current income and preserve
     capital while maintaining  high levels  of liquidity  through investing  in
     high quality money market instruments with remaining maturities of one year
     or less.
 
    -The  MUNICIPAL MONEY MARKET PORTFOLIO  seeks to maximize current tax-exempt
     income and  preserve capital  while maintaining  high levels  of  liquidity
     through  investing in high quality  money market instruments with remaining
     maturities of one year or less which are exempt from federal income tax.
 
    THE CHINA  GROWTH, MICROCAP  AND MORTGAGE-BACKED  SECURITIES PORTFOLIOS  ARE
    CURRENTLY NOT BEING OFFERED.
 
INVESTMENT MANAGEMENT
 
   
    Morgan  Stanley Asset Management  Inc., a wholly  owned subsidiary of Morgan
Stanley Group  Inc.,  which,  together  with  its  affiliated  asset  management
companies,  at March  31, 1997  had in  excess of  $118 billion  in assets under
management as  an  investment  manager  or  as  a  fiduciary  adviser,  acts  as
investment  adviser to the Fund  and each of its  portfolios. See "Management of
the Fund -- Investment Adviser" and "Management of the Fund -- Administrator."
    
 
HOW TO INVEST
 
    Class A shares of  each Portfolio are offered  directly to investors at  net
asset  value with no sales  commission or 12b-1 charges.  Class B shares of each
Portfolio are offered at net  asset value with no  sales commission, but with  a
12b-1  fee, which  is accrued daily  and paid  quarterly, equal to  0.25% of the
Class B shares'  average daily net  assets on an  annualized basis. The  minimum
initial  investment, generally, is $500,000 for Class A shares of each Portfolio
and $100,000  for  Class  B  shares  of  each  Portfolio.  The  minimum  initial
investment amount is reduced for certain categories of investors. For additional
information  on  how to  purchase shares  and  minimum initial  investments, see
"Purchase of Shares."
 
HOW TO REDEEM
 
    Shares of each Portfolio may be redeemed  at any time, without cost, at  the
net  asset value  per share  of shares of  the applicable  class next determined
after receipt of  the redemption request.  The redemption price  may be more  or
less  than the purchase  price. Certain redemptions  that cause the  value of an
account to remain for  a continuous 60-day period  below the minimum  investment
amount  for  Class A  shares or  for Class  B shares  may result  in involuntary
redemption or conversion. For additional information on how to redeem shares and
involuntary redemption or conversion, see "Purchase of Shares -- Minimum Account
Sizes and Involuntary Redemption of Shares" and "Redemption of Shares."
 
                                       9
<PAGE>
RISK FACTORS
 
   
    Investing in emerging country securities involves certain considerations not
typically associated with investing in  securities of U.S. companies,  including
(1)  restrictions on foreign investment and  on repatriation of capital invested
in emerging countries,  (2) currency  fluctuations, (3) the  cost of  converting
foreign  currency into U.S.  dollars, (4) potential  price volatility and lesser
liquidity of shares traded on emerging  country securities markets or lack of  a
secondary  trading market  for such  securities and  (5) political  and economic
risks, including the risk of nationalization or expropriation of assets and  the
risk  of war. In  addition, accounting, auditing,  financial and other reporting
standards in  emerging  countries  are  not equivalent  to  U.S.  standards  and
therefore,  disclosure of certain material information  may not be made and less
information may be available to  investors investing in emerging countries  than
in  the United States.  There is also generally  less governmental regulation of
the securities  industry  in  emerging  countries than  in  the  United  States.
Moreover,  it may be more difficult to obtain  a judgment in a court outside the
United States. For  temporary, defensive purposes,  when the Adviser  determines
that  market conditions  warrant, each  Portfolio may invest  up to  100% of its
assets in money market  instruments and short-  and medium-term debt  securities
that  the Adviser believes to be of  high quality, or hold cash. See "Additional
Investment Information -- Temporary Investments."  The Portfolios may invest  in
certain  derivatives, including options,  futures and options  on futures. These
investments entail  certain costs  and  risks, including  imperfect  correlation
between  the  value of  securities  held by  a Portfolio  and  the value  of the
particular derivative instrument, and the risk that a Portfolio could not  close
out  a derivatives position  when it would  be most advantageous  to do so. Each
Portfolio  may   invest  in   depositary   receipts,  investment   funds,   loan
participations   and  assignments,   non-publicly  traded   securities,  private
placements, restricted securities and repurchase agreements, lend its  portfolio
securities  and  purchase  securities  on a  when-issued  basis.  Each  of these
investment  strategies  involves  specific  risks  which  are  described   under
"Investment  Objectives  and Policies"  and "Additional  Investment Information"
herein.
    
 
    The Emerging Markets Portfolio  may invest in  equity securities of  Russian
companies.  The registration, clearing and settlement of securities transactions
in Russia  are  subject  to  significant  risks  not  normally  associated  with
securities  transactions in the United States  and other more developed markets.
See "Additional Investment Information -- Russian Securities Transactions."
 
                                       10
<PAGE>
                       INVESTMENT OBJECTIVES AND POLICIES
 
    The investment objective of each Portfolio is described below, together with
the policies the Portfolios employ in their efforts to achieve these objectives.
Each Portfolio's investment objective is a  fundamental policy which may not  be
changed without the approval of a majority of the Portfolio's outstanding voting
securities.  There  is  no  assurance  that  the  Portfolios  will  attain their
objective. In addition to  the investments and  strategies described below,  the
Portfolios  may invest  in certain  securities and  obligations as  set forth in
"Additional Investment  Information" below  and as  described under  "Investment
Objectives  and  Policies"  in  the  Statement  of  Additional  Information. The
investment policies  described below  are not  fundamental policies  and may  be
changed without shareholder approval.
 
THE EMERGING MARKETS PORTFOLIO
 
    The  investment objective of  the Portfolio is  to provide long-term capital
appreciation by investing  primarily in  equity securities  of emerging  country
issuers.  With respect  to the Portfolio,  equity securities  include common and
preferred stocks, convertible securities, rights and warrants to purchase common
stocks. The  Portfolio  may  also  invest indirectly  in  equity  securities  of
emerging  country issuers through depositary  receipts. Under normal conditions,
at least  65% of  the Portfolio's  total  assets will  be invested  in  emerging
country  equity  securities.  As used  in  this Prospectus,  the  term "emerging
country" applies  to  any country  which,  in the  opinion  of the  Adviser,  is
generally  considered to be  an emerging country  by the international financial
community, including the International  Bank for Reconstruction and  Development
(more   commonly  known  as  the  World  Bank)  and  the  International  Finance
Corporation. There are currently over 130 countries which, in the opinion of the
Adviser, are generally considered to be emerging or developing countries by  the
international  financial  community, approximately  40  of which  currently have
stock markets.  These countries  generally  include every  nation in  the  world
except the United States, Canada, Japan, Australia, New Zealand and most nations
located  in Western Europe.  Currently, investing in  many emerging countries is
not feasible or  may involve  unacceptable political risks.  The Portfolio  will
focus  its investments on  those emerging market countries  in which it believes
the economies are developing strongly and in which the markets are becoming more
sophisticated. The Portfolio intends to invest  primarily in some or all of  the
following countries:
 
<TABLE>
<S>                     <C>                     <C>                     <C>
Argentina               Hungary                 Nigeria
Botswana                India                   Pakistan                South Korea
Brazil                  Indonesia               Peru                    Sri Lanka
Chile                   Jamaica                 Philippines             Taiwan
China                   Jordan                  Poland                  Thailand
Colombia                Kenya                   Portugal                Turkey
Greece                  Malaysia                Russia                  Venezuela
Hong Kong               Mexico                  South Africa            Zimbabwe
</TABLE>
 
As  markets  in other  countries develop,  the Portfolio  expects to  expand and
further diversify the emerging countries in which it invests. The Portfolio does
not intend to  invest in any  security in a  country where the  currency is  not
freely  convertible  to  U.S. dollars,  unless  the Portfolio  has  obtained the
necessary governmental licensing to convert such currency or other appropriately
licensed or sanctioned contractual guarantees to protect such investment against
loss of  that currency's  external  value, or  the  Portfolio has  a  reasonable
 
                                       11
<PAGE>
expectation  at the time the investment is made that such governmental licensing
or other appropriately licensed  or sanctioned guarantees  would be obtained  or
that the currency in which the security is quoted would be freely convertible at
the time of any proposed sale of the security by the Portfolio.
 
    An emerging country security is one issued by a company that, in the opinion
of  the  Adviser, has  one or  more  of the  following characteristics:  (i) its
principal securities trading market is in an emerging country, (ii) alone, or on
a consolidated basis, the company derives 50% or more of its annual revenue from
either goods produced, sales made  or services performed in emerging  countries;
or  (iii) the company is organized under the laws of, and has a principal office
in, an emerging country. The Adviser will base determinations as to  eligibility
on publicly available information and inquiries made to the companies.
 
    To  the  extent that  the Portfolio's  assets are  not invested  in emerging
country equity securities, the  remainder of the assets  may be invested in  (i)
debt  securities denominated in the currency of an emerging country or issued or
guaranteed by  an emerging  country company  or the  government of  an  emerging
country,  (ii) equity  or debt securities  of corporate  or governmental issuers
located in  industrialized  countries, and  (iii)  short- and  medium-term  debt
securities  of the type described below under "Additional Investment Information
- -- Temporary  Investments."  The Portfolio's  assets  may be  invested  in  debt
securities when the Portfolio believes that, based upon factors such as relative
interest  rate levels  and foreign  exchange rates,  such debt  securities offer
opportunities for long-term capital appreciation. It is likely that many of  the
debt  securities in which the Portfolio will invest will be unrated and, whether
or not rated, such securities may have speculative characteristics. When  deemed
appropriate  by the  Adviser, the Portfolio  may invest  up to 10%  of its total
assets  (measured  at  the  time  of  the  investment)  in  lower  quality  debt
securities. Lower quality debt securities, also known as "junk bonds," are often
considered  to  be speculative  and  involve greater  risk  of default  or price
changes due to changes in the issuer's creditworthiness. As of the date of  this
prospectus,  less than 5% of the Portfolio's  total assets were invested in junk
bonds. The market prices  of these securities may  fluctuate more than those  of
higher  quality securities and  may decline significantly  in periods of general
economic  difficulty,  which  may  follow  periods  of  rising  interest  rates.
Securities  in the lowest quality  category may present the  risk of default, or
may be in default.
 
THE EMERGING MARKETS DEBT PORTFOLIO
 
    The investment objective of the Portfolio  is to seek high total return.  In
seeking  to achieve this objective,  the Portfolio will seek  to invest at least
65% of its total assets in debt securities of government and  government-related
issuers located in emerging countries (including participations in loans between
governments   and  financial   institutions),  and  of   entities  organized  to
restructure outstanding debt  of such  issuers. In addition,  the Portfolio  may
invest  up to 35%  of its total  assets in debt  securities of corporate issuers
located in or organized under the laws of emerging countries. See "The  Emerging
Markets Portfolio" above for a definition of emerging countries.
 
    The  Adviser intends  to invest the  Portfolio's assets  in emerging country
debt securities that provide a high level  of current income, while at the  same
time   holding  the  potential   for  capital  appreciation   if  the  perceived
 
                                       12
<PAGE>
creditworthiness of the  issuer improves due  to improving economic,  financial,
political,  social or  other conditions  in the country  in which  the issuer is
located. Currently,  investing  in  many  emerging  country  securities  is  not
feasible  or may involve unacceptable  political risks. Initially, the Portfolio
expects that its investments  in emerging country debt  securities will be  made
primarily in some or all of the following emerging countries:
 
<TABLE>
<S>                     <C>                     <C>
Algeria                 India                   Philippines
Argentina               Indonesia               Poland
Brazil                  Ivory Coast             Portugal
Bulgaria                Jamaica                 Russia
Chile                   Jordan                  Slovakia
China                   Malaysia                South Africa
Colombia                Mexico                  Thailand
Costa Rica              Morocco                 Trinidad & Tobago
Czech Republic          Nicaragua               Tunisia
Dominican Republic      Nigeria                 Turkey
Ecuador                 Pakistan                Uruguay
Egypt                   Panama                  Venezuela
Greece                  Paraguay                Zaire
Hungary                 Peru
</TABLE>
 
As  opportunities to invest  in debt securities in  other countries develop, the
Portfolio expects  to expand  and further  diversify the  emerging countries  in
which it invests. While the Portfolio generally is not restricted in the portion
of  its  assets which  may be  invested in  a  single country  or region,  it is
anticipated that,  under  normal  conditions, the  Portfolio's  assets  will  be
invested in issuers in at least three countries.
 
    Emerging  country debt securities  that the Portfolio  may invest in include
bonds, notes,  bills, debentures,  convertible securities,  warrants, bank  debt
obligations,  short-term paper, mortgage and other asset-backed securities, loan
participations, loan assignments and interests issued by entities organized  and
operated  for  the purpose  of restructuring  the investment  characteristics of
instruments issued by emerging country issuers. U.S. dollar-denominated emerging
country debt securities held by the  Portfolio will generally be listed but  not
traded on a securities exchange, and non-U.S. dollar-denominated securities held
by  the Portfolio may or  may not be listed or  traded on a securities exchange.
The Portfolio  will be  subject to  no  restrictions on  the maturities  of  the
emerging  country  debt securities  it holds;  those  maturities may  range from
overnight to 30 years.
 
    The Portfolio is not restricted  in the portion of  its assets which may  be
invested  in securities denominated  in a particular  currency and a substantial
portion of the Portfolio's assets may be invested in non-U.S. dollar-denominated
securities. The  portion  of  the  Portfolio's  assets  invested  in  securities
denominated  in currencies  other than  the U.S.  dollar will  vary depending on
market conditions.  Although the  Portfolio is  permitted to  engage in  a  wide
variety of investment practices designed to hedge against currency exchange rate
risks   with  respect  to  its  holdings  of  non-U.S.  dollar-denominated  debt
securities, the Portfolio may be limited  in its ability to hedge against  these
risks.
 
    In  selecting particular emerging country  debt securities for investment by
the Portfolio,  the Adviser  will  apply a  market risk  analysis  contemplating
assessment   of  factors  such  as   liquidity,  volatility,  tax  implications,
 
                                       13
<PAGE>
interest   rate   sensitivity,   counterparty   risks   and   technical   market
considerations.  Emerging  country debt  securities in  which the  Portfolio may
invest will be subject to high risk and  will not be required to meet a  minimum
rating standard and may not be rated for creditworthiness by any internationally
recognized  credit rating organization. The Portfolio's investments are expected
to be  rated  in the  lower  and  lowest rating  categories  of  internationally
recognized  credit rating organizations or are expected to be unrated securities
of comparable  quality.  These  types  of  debt  obligations  are  predominantly
speculative  with respect to the capacity to pay interest and repay principal in
accordance with their terms and generally involve a greater risk of default  and
of  volatility in price than securities  in higher rating categories. Ratings of
non-U.S. debt instruments, to the extent undertaken, are related to  evaluations
of  the country in which  the issuer of the  instrument is located and generally
take  into  account  the  currency  in  which  a  non-U.S.  debt  instrument  is
denominated.  Instruments issued by a foreign government in other than the local
currency, typically have a lower rating  than local currency instruments due  to
the  risk that  the government  will be  unable to  obtain the  required foreign
currency to  service  its foreign  currency-denominated  debt. In  general,  the
ratings of debt securities or obligations issued by a non-U.S. public or private
entity  will  not be  higher  than the  rating of  the  currency or  the foreign
currency debt of the central  government of the country  in which the issuer  is
located, regardless of the intrinsic creditworthiness of the issuer.
 
    The   Portfolio's   investments   in   government,   government-related  and
restructured debt securities will consist of (i) debt securities or  obligations
issued  or guaranteed by governments, governmental agencies or instrumentalities
and   political   subdivisions   located   in   emerging   countries   including
participations  in loans  between governments  and financial  institutions, (ii)
debt securities  or  obligations  issued  by  government  owned,  controlled  or
sponsored   entities  located  in  emerging  countries,  and  (iii)  issuers  of
structured securities.  Certain issuers  of such  structured securities  may  be
deemed  to be "investment companies" as defined in the Investment Company Act of
1940 (the  "1940  Act").  As  a  result,  the  Portfolio's  investment  in  such
securities  may be limited  by certain investment  restrictions contained in the
1940 Act.  The Portfolio's  investments  in government,  government-related  and
restructured  debt  instruments  are  subject to  special  risks,  including the
inability  or  unwillingness  to  repay  principal  and  interest,  requests  to
reschedule  or restructure  outstanding debt  and requests  to extend additional
loan amounts. The Portfolio may have limited recourse in the event of default on
such debt instruments.
 
    The Portfolio's  investments  in debt  securities  of corporate  issuers  in
emerging  countries may  include debt  securities or  obligations issued  (i) by
banks located in  emerging countries or  by branches of  emerging country  banks
located  outside the country or (ii) by companies organized under the laws of an
emerging country. Determinations as to eligibility  will be made by the  Adviser
based  on publicly available  information and inquiries made  to the issuer. The
Portfolio may also invest in certain debt obligations customarily referred to as
"Brady Bonds," which  are created  through the exchange  of existing  commercial
bank  loans  to foreign  entities for  new obligations  in connection  with debt
restructurings under a plan introduced by former U.S. Secretary of the  Treasury
Nicholas F. Brady.
 
    The  Portfolio  may  also invest  in  zero coupon,  pay-in-kind  or deferred
payment securities and in securities that  may be collateralized by zero  coupon
securities (such as Brady Bonds). Zero coupon securities are securities that are
sold  at a  discount to par  value and on  which interest payments  are not made
during the  life of  the security.  Upon  maturity, the  holder is  entitled  to
receive  the par value of the security.  While interest payments are not made on
such securities, the Portfolio accrues income, or "Phantom Income," with respect
to these
 
                                       14
<PAGE>
securities prior to the receipt of cash payments. The Portfolio will  distribute
its  "phantom income" to shareholders and, to the extent that shareholders elect
to  receive  dividends  in  cash  rather  than  reinvesting  such  dividends  in
additional  shares, the Portfolio  will have fewer  assets available to purchase
income producing securities. Pay-in-kind securities pay interest by delivery  of
additional  securities. Upon  maturity, the  holder is  entitled to  receive the
aggregate par value of the  securities. Deferred payment securities remain  zero
coupon  securities until a  predetermined date, at which  time the stated coupon
rate becomes effective and interest  becomes payable at regular intervals.  Zero
coupon,  pay-in-kind and deferred  payment securities may  be subject to greater
fluctuation in  value  and lesser  liquidity  in  the event  of  adverse  market
conditions  than comparably rated  securities that pay  cash interest at regular
interest payment periods.
 
    The  Portfolio  may  also   invest  up  to  5%   of  its  total  assets   in
mortgage-backed  securities  and  in  other  asset-backed  securities  issued by
non-governmental entities,  such  as  banks and  other  financial  institutions.
Mortgage-backed   securities  include   mortgage  pass-through   securities  and
collateralized mortgage obligations. Asset-backed securities are  collateralized
by  such assets  as automobile  or credit  card receivables  and are securitized
either in a pass-through  structure or in a  pay-through structure similar to  a
CMO.
 
                       ADDITIONAL INVESTMENT INFORMATION
 
    BORROWING  AND OTHER FORMS OF LEVERAGE.  The Emerging Markets Debt Portfolio
is authorized to borrow money from banks  and other entities in an amount up  to
33 1/3% of the Portfolio's total assets (including the amount borrowed) less all
liabilities  and indebtedness other than the borrowing, and may use the proceeds
of the borrowing  for investment  purposes or  to pay  dividends. Borrowing  for
investment  purposes  creates leverage  which  is a  speculative characteristic.
Although the Portfolio  is authorized to  borrow, it  will do so  only when  the
Adviser  believes that  borrowing will benefit  the Portfolio  after taking into
account considerations  such  as the  costs  of  the borrowing  and  the  likely
investment  returns on securities  purchased with borrowed  monies. Borrowing by
the Portfolio will create the opportunity  for increased net income but, at  the
same  time, will involve special risk considerations. Leverage that results from
borrowing will magnify  declines as  well as  increases in  the Portfolio's  net
asset value per share and net yield.
 
    The  Portfolio expects that all  of its borrowing will  be made on a secured
basis. The Portfolio's Custodian will  either segregate the assets securing  the
borrowing  for the benefit  of the lenders  or arrangements will  be made with a
suitable sub-custodian.  If assets  used  to secure  the borrowing  decrease  in
value,  the Portfolio  may be  required to  pledge additional  collateral to the
lender in the form of cash or securities to avoid liquidation of those assets.
 
   
    DEPOSITARY RECEIPTS.   The  Portfolios may  invest in  Depositary  Receipts,
including  American  Depositary  Receipts ("ADRs"),  Global  Depositary Receipts
("GDRs"), European Depositary  Receipts ("EDRs") and  other Depositary  Receipts
(which, together with ADRs, GDRs and EDRs, are hereinafter collectively referred
to as "Depositary Receipts"), to the extent that such Depositary Receipts are or
become  available. ADRs  are securities,  typically issued  by a  U.S. financial
institution (a "depositary"), that evidence ownership interests in a security or
a pool of securities  issued by a foreign  issuer (the "underlying issuer")  and
deposited  with the depositary. ADRs include  American Depositary Shares and New
York Shares  and  may  be  "sponsored"  or  "unsponsored."  Sponsored  ADRs  are
established   jointly  by  a  depositary  and  the  underlying  issuer,  whereas
unsponsored ADRs may be established by a depositary without participation by the
underlying issuer.  The  issuers  of  the stock  of  unsponsored  ADRs  are  not
obligated    to   disclose   material   information   in   the   United   States
    
 
                                       15
<PAGE>
   
and therefore, there may not be  a correlation between such information and  the
market  value of the ADR. GDRs, EDRs  and other types of Depositary Receipts are
typically issued by foreign  depositaries, although they may  also be issued  by
U.S.  depositaries, and  evidence ownership interests  in a security  or pool of
securities issued  by  either  a  foreign  or  a  U.S.  corporation.  Generally,
Depositary  Receipts  in  registered  form  are designed  for  use  in  the U.S.
securities market and Depositary Receipts in bearer form are designed for use in
securities markets  outside the  United  States. The  Portfolios may  invest  in
sponsored  and unsponsored Depositary Receipts.  For purposes of the Portfolios'
investment policies, the Portfolios' investments in Depositary Receipts will  be
deemed to be investments in the underlying securities.
    
 
   
    FOREIGN  CURRENCY FORWARD CONTRACTS.  The  Portfolios may enter into foreign
currency forward contracts ("forward contracts")  that provide for the  purchase
or  sale of an amount  of a specified currency at  a future date. The Portfolios
may use  such contracts  to protect  against  a decline  in a  foreign  currency
against  the U.S.  dollar between  the trade date  and settlement  date when the
Portfolio purchases  or sells  securities,  lock in  the  U.S. dollar  value  of
dividends  and interest  on securities held  by the Portfolio,  and generally to
protect the  U.S. dollar  value  of securities  held  by the  Portfolio  against
exchange  rate fluctuation. While forward contracts may limit losses as a result
of exchange  rate  fluctuations, they  will  also  limit any  gains  that  might
otherwise have been realized. The Portfolio's Custodian may be required to place
cash  or liquid  securities in a  segregated account  in an amount  equal to the
value of the Portfolio's total assets  committed to the consummation of  forward
contracts.  If  the value  of the  securities placed  in the  segregated account
declines, additional cash or securities will be placed in the account on a daily
basis so that the value of the account  will be at least equal to the amount  of
the Portfolio's commitments with respect to such contracts.
    
 
   
    FOREIGN  INVESTMENT.  Investment  in securities of  foreign issuers involves
somewhat different  investment risks  than those  affecting securities  of  U.S.
domestic  issuers.  There may  be  limited publicly  available  information with
respect to foreign  issuers, and foreign  issuers are not  generally subject  to
uniform  accounting, auditing  and financial  and other  reporting standards and
requirements comparable to those applicable to U.S. companies. There may also be
less government  supervision and  regulation  of foreign  securities  exchanges,
brokers  and listed companies than in the United States. Many foreign securities
markets have substantially less volume than U.S. national securities  exchanges,
and  securities of some foreign  issuers are less liquid  and more volatile than
securities of  comparable  domestic  issuers. Brokerage  commissions  and  other
transaction  costs on foreign securities exchanges  are generally higher than in
the United States Dividends and interest paid by foreign issuers may be  subject
to  withholding and other  foreign taxes, which  may decrease the  net return on
foreign investments  as compared  to  dividends and  interest paid  by  domestic
companies.  Additional risks include future political and economic developments,
the possibility that a foreign  jurisdiction might impose or change  withholding
taxes  on income payable  with respect to  foreign securities, possible seizure,
nationalization or expropriation of the  foreign issuer or foreign deposits  and
the  possible  adoption of  foreign governmental  restrictions such  as exchange
controls.
    
 
   
    Prior governmental approval  for foreign investments  may be required  under
certain  circumstances in  some emerging  countries, and  the extent  of foreign
investment in certain debt securities and  domestic companies may be subject  to
limitation  in other emerging countries.  Foreign ownership limitations also may
be imposed by  the charters  of individual  companies in  emerging countries  to
prevent, among other concerns, violation of foreign investment limitations.
    
 
                                       16
<PAGE>
   
    Repatriation  of investment  income, capital  and the  proceeds of  sales by
foreign investors may require governmental registration and/or approval in  some
emerging  countries. The Portfolios could be adversely affected by delays in, or
a refusal to grant, any required governmental registration or approval for  such
repatriation.  Any  investment subject  to  such repatriation  controls  will be
considered illiquid if it appears reasonably likely that this process will  take
more than seven days.
    
 
   
    The  economies  of individual  emerging  countries may  differ  favorably or
unfavorably from the U.S. economy in  such respects as growth of gross  domestic
product,   rate  of  inflation,  currency  depreciation,  capital  reinvestment,
resource  self-sufficiency  and  balance  of  payments  position.  Further,  the
economies   of  emerging   countries  generally   are  heavily   dependent  upon
international trade  and,  accordingly,  have  been, and  may  continue  to  be,
adversely  affected by trade barriers, exchange controls, managed adjustments in
relative currency values and other protectionist measures imposed or  negotiated
by  the countries with which they trade. These economies also have been, and may
continue to be, adversely affected by economic conditions in the countries  with
which they trade.
    
 
   
    With   respect  to  any  emerging  country,  there  is  the  possibility  of
nationalization, expropriation  or  confiscatory  taxation,  political  changes,
government  regulation, social instability or diplomatic developments (including
war) which could affect adversely the  economies of such countries or the  value
of  each  Portfolio's investments  in those  countries. In  addition, it  may be
difficult to obtain  and enforce a  judgment in  a court outside  of the  United
States.
    
 
   
    Investments  in securities of foreign  issuers are frequently denominated in
foreign currencies, and because each  Portfolio may temporarily hold  uninvested
reserves  in bank deposits in foreign  currencies, the value of each Portfolio's
assets, as measured in U.S. dollars, may be affected favorably or unfavorably by
changes in currency rates and in exchange control regulations and the Portfolios
may incur costs in connection with conversions between various currencies.
    
 
   
    The Emerging Markets Portfolio may  invest in securities of issuers  located
in  Hong Kong. Hong Kong  was established as a British  colony in the 1840's and
has been  ruled  by  the  British  Government  through  an  appointed  Governor.
Effective  July 1, 1997,  Hong Kong reverts  to Chinese sovereignty  and will be
ruled as  a Special  Administrative Region  of China.  Although China  has  made
certain  commitments  to preserve  the  economic and  social  freedoms currently
enjoyed in Hong  Kong, there can  be no assurances  China's commitments will  be
maintained.  Action  taken  by the  Chinese  government which  limits  or causes
uncertainty with regard  to these  economic and  social freedoms  could have  an
adverse  affect on the Portfolio's investments  in securities of issuers located
in Hong Kong.
    
 
   
    FUTURES CONTRACTS  AND OPTIONS  ON FUTURES  CONTRACTS.   The Portfolios  may
purchase  and sell futures contracts and options on futures contracts, including
but not limited to financial futures, securities index futures, foreign currency
exchange futures, and interest rate futures contracts. Futures contracts provide
for the sale by one party and purchase by another party of a specified amount of
a specific security, instrument or basket thereof, at a specific future date and
at a specified price. An option on  a futures contract is a legal contract  that
gives  the  holder  the right  to  buy or  sell  a specified  amount  of futures
contracts at a fixed or determinable price upon the exercise of the option.
    
 
   
    The Portfolios may  sell securities index  futures contracts and/or  options
thereon  in anticipation of or during a  market decline to attempt to offset the
decrease  in  market  value  of  investments  in  its  portfolio,  or   purchase
    
 
                                       17
<PAGE>
   
securities index futures in order to gain market exposure. Subject to applicable
laws,  the Portfolios  may engage  in transactions  in securities  index futures
contracts (and options thereon) which are  traded on a recognized securities  or
futures   exchange,  or   may  purchase   or  sell   such  instruments   in  the
over-the-counter market. There  currently are limited  securities index  futures
and  options on such futures in many countries, particularly emerging countries.
The nature of the  strategies adopted by  the Adviser, and  the extent to  which
those strategies are used, may depend on the development of such markets.
    
 
   
    The  Portfolios  may  engage  in  transactions  involving  foreign  currency
exchange futures contracts. Such contracts involve an obligation to purchase  or
sell  a specific currency at  a specified future date  and at a specified price.
The Portfolios  may  engage  in  such transactions  to  hedge  their  respective
holdings  and commitments against changes in  the level of future currency rates
or to gain exposure to a particular currency.
    
 
   
    The  Portfolios  may  engage  in  transactions  in  interest  rate   futures
transactions.  Interest rate futures contracts involve an obligation to purchase
or sell a specific  debt security, instrument or  basket thereof at a  specified
future  date at  a specified price.  The value  of the contract  rises and falls
inversely with changes  in interest  rates. The  Portfolios may  engage in  such
transactions  to hedge their holdings of debt instruments against future changes
in interest rates.
    
 
   
    Financial futures are futures  contracts relating to financial  instruments,
such  as  U.S. Government  securities, foreign  currencies, and  certificates of
deposit. Such contracts  involve an obligation  to purchase or  sell a  specific
security, instrument or basket thereof at a specified future date at a specified
price.  Like interest  rate futures  contracts, the  value of  financial futures
contracts rises  and  falls  inversely  with  changes  in  interest  rates.  The
Portfolios may engage in financial futures contracts for hedging and non-hedging
purposes.
    
 
   
    Under  rules  adopted  by  the Commodity  Futures  Trading  Commission, each
Portfolio may enter into futures contracts and options thereon for both  hedging
and  non-hedging purposes,  provided that not  more than 5%  of such Portfolios'
total assets at the time of entering the transaction are required as margin  and
option   premiums  to  secure  obligations  under  such  contracts  relating  to
activities that do not constitute "bona  fide" hedging. No Portfolio will  enter
into  futures  contracts  to  the extent  that  its  outstanding  obligations to
purchase securities under  such contracts, in  combination with its  outstanding
obligations  with respect to options transactions (including options to purchase
securities or instruments) would exceed 20% of its total assets.
    
 
   
    Gains and losses  on futures  contracts and  options thereon  depend on  the
Adviser's  ability  to predict  correctly  the direction  of  securities prices,
interest rates and other economic factors.  Other risks associated with the  use
of  futures  and options  are (i)  imperfect correlation  between the  change in
market value of investments held  by a Portfolio and  the prices of futures  and
options  relating to  investments purchased or  sold by the  Portfolio, and (ii)
possible lack  of a  liquid secondary  market  for a  futures contract  and  the
resulting  inability to close a futures position. The risk that a Portfolio will
be unable to close out a futures position or options contract will be  minimized
by  only entering into futures contracts or options transactions for which there
appears to be a liquid exchange or secondary market. The risk of loss in trading
on futures contracts in some strategies can be substantial, due both to the  low
margin  deposits required and the extremely  high degree of leverage involved in
futures pricing.
    
 
    INVESTMENT FUNDS.  Some  emerging countries have  laws and regulations  that
currently  preclude  direct  foreign  investment  in  the  securities  of  their
companies. However, indirect foreign investment  in the securities of  companies
listed  and traded  on the  stock exchanges in  these countries  is permitted by
certain emerging
 
                                       18
<PAGE>
countries through investment funds which have been specifically authorized.  The
Portfolios may invest in these investment funds subject to the provisions of the
1940  Act  and  other  applicable  laws  as  discussed  below  under "Investment
Restrictions." If a Portfolio invests in such investment funds, the  Portfolio's
shareholders will bear not only their proportionate share of the expenses of the
Portfolio  (including operating expenses and the  fees of the Adviser), but also
will indirectly bear similar expenses of the underlying investment funds.
 
    Certain of the investment funds referred  to in the preceding paragraph  are
advised  by the Adviser. These Portfolios may, to the extent permitted under the
1940 Act  and other  applicable law,  invest  in these  investment funds.  If  a
Portfolio  does elect to make an investment  in such an investment fund, it will
only purchase the securities of such investment fund in the secondary market.
 
    LOAN PARTICIPATIONS AND  ASSIGNMENTS.   The Portfolios may  invest in  fixed
rate  and floating  rate loans  ("Loans") arranged  through private negotiations
between an  issuer of  sovereign  debt obligations  and  one or  more  financial
institutions  ("Lenders"). The Portfolio's investments  in Loans are expected in
most instances to be  in the form of  participation in Loans  ("Participations")
and assignments of all or a portion of Loans ("Assignments") from third parties.
The Portfolio will have the right to receive payments of principal, interest and
any  fees to which it is entitled only from the Lender selling the Participation
and only upon receipt by  the Lender of the payments  from the borrower. In  the
event of the insolvency of the Lender selling a Participation, the Portfolio may
be  treated as  a general creditor  of the Lender  and may not  benefit from any
set-off between  the Lender  and  the borrower.  Certain Participations  may  be
structured  in a  manner designed  to avoid  purchasers of  Participations being
subject to the credit risk of the Lender with respect to the Participation. Even
under such a structure,  in the event of  the Lender's insolvency, the  Lender's
servicing  of  the Participation  may be  delayed and  the assignability  of the
Participation may be impaired. The Portfolio will acquire Participations only if
the Lender interpositioned between the Portfolio and the borrower is  determined
by the Adviser to be creditworthy.
 
    When the Portfolio purchases Assignments from Lenders it will acquire direct
rights  against  the  borrower on  the  Loan. However,  because  Assignments are
arranged through private negotiations between potential assignees and  potential
assignors, the rights and obligations acquired by the Portfolio as the purchaser
of  an Assignment may differ  from, and be more limited  than, those held by the
assigning Lender. Because  there is no  liquid market for  such securities,  the
Portfolio  anticipates  that such  securities could  be sold  only to  a limited
number of institutional  investors. The lack  of a liquid  secondary market  may
have  an adverse  impact on  the value  of such  securities and  the Portfolio's
ability to dispose of particular Assignments or Participations when necessary to
meet the Portfolio's liquidity needs or in response to a specific economic event
such as a deterioration in the creditworthiness  of the borrower. The lack of  a
liquid secondary market for Assignments and Participations also may make it more
difficult  for the Portfolio to assign a  value to these securities for purposes
of valuing the Portfolio's portfolio and calculating its net asset value.
 
    LOANS OF  PORTFOLIO  SECURITIES.   The  Portfolios may  lend  securities  to
brokers, dealers, domestic and foreign banks or other financial institutions for
the  purpose  of increasing  their net  investment income.  These loans  must be
secured continuously by cash or equivalent collateral, or by a letter of  credit
at  least  equal to  the  market value  of  the securities  loaned  plus accrued
interest or income. There may be a  risk of delay in recovery of the  securities
or  even loss of rights in the  collateral should the borrower of the securities
fail  financially.  Each   Portfolio  will  not   enter  into  securities   loan
transactions exceeding in the aggregate 33 1/3% of the market value of its total
assets.
 
                                       19
<PAGE>
   
    MONEY  MARKET INSTRUMENTS.   Each Portfolio is permitted  to invest in money
market  instruments,  although  each  Portfolio  intends  to  stay  invested  in
securities  satisfying its primary investment objective to the extent practical.
The Portfolios may  make money  market investments pending  other investment  or
settlement  for  liquidity,  or  in adverse  market  conditions.  See "Temporary
Investments." The money market investments permitted for the Portfolios  include
obligations  of  the U.S.  government  and its  agencies  and instrumentalities;
obligations of foreign sovereignties;  other debt securities; commercial  paper;
bank  obligations; certificates of deposit (including Eurodollar certificates of
deposit); and repurchase agreements.
    
 
    NON-PUBLICLY  TRADED   SECURITIES,   PRIVATE   PLACEMENTS   AND   RESTRICTED
SECURITIES.   The Portfolios may invest in securities that are neither listed on
a  stock  exchange  nor  traded  over-the-counter,  including  privately  placed
securities.  Investing  in  such unlisted  emerging  country  equity securities,
including investments  in new  and early  stage companies,  may involve  a  high
degree  of business and financial risk that can result in substantial losses. As
a result of the absence  of a public trading  market for these securities,  they
may  be less liquid  than publicly traded  securities. Although these securities
may be resold  in privately  negotiated transactions, the  prices realized  from
these  sales could be less than those  originally paid by the Portfolios or less
than what  may  be  considered  the fair  value  of  such  securities.  Further,
companies  whose securities are  not publicly traded  may not be  subject to the
disclosure and other investor protection requirements which might be  applicable
if  their securities were publicly traded. If such securities are required to be
registered under the securities laws of  one or more jurisdictions before  being
resold, the Portfolios may be required to bear the expenses of registration.
 
    As  a general matter, each Portfolio may not invest more than 15% of its net
assets in  illiquid  securities, including  securities  for which  there  is  no
readily available secondary market. Nor, as a general matter, may each Portfolio
invest  more than 10% of its total assets in securities that are restricted from
sale to  the public  without registration  ("Restricted Securities")  under  the
Securities  Act of 1933 (the "1933 Act").  However, each Portfolio may invest up
to 25% of its total assets in  liquid Restricted Securities that can be  offered
and  sold to qualified institutional  buyers under Rule 144A  under the 1933 Act
("Rule 144A  Securities"). The  Board of  Directors has  adopted guidelines  and
delegated  to the Adviser, subject to the supervision of the Board of Directors,
the daily function  of determining  and monitoring  the liquidity  of Rule  144A
Securities.  Rule 144A securities may become illiquid if qualified institutional
buyers are not interested in acquiring the securities.
 
   
    OPTIONS TRANSACTIONS.  The Portfolios may seek to increase their returns  or
may  hedge their portfolio investments through options transactions with respect
to securities, instruments, indices or baskets thereof in which such  Portfolios
may invest, as well as with respect to foreign currency. Purchasing a put option
gives  a Portfolio the right to sell a specified security, currency or basket of
securities or  currencies at  the exercise  price until  the expiration  of  the
option.  Purchasing a  call option  gives a  Portfolio the  right to  purchase a
specified security,  currency  or basket  of  securities or  currencies  at  the
exercise  price until the expiration of the option. A Portfolio may not purchase
call and put options to the extent that the value of its aggregate investment in
options, excluding options on futures contracts, exceeds 5% of its total assets.
    
 
   
    The Portfolios  also  may  write  (i.e.,  sell)  put  and  call  options  on
investments  held in its portfolio, as well as with respect to foreign currency.
A Portfolio that has written an  option receives a premium, which increases  the
Portfolio's  return on  the underlying security  or instrument in  the event the
option expires unexercised or is closed out  at a profit. However, by writing  a
call  option, a Portfolio will limit its  opportunity to profit from an increase
in the market value of the underlying security or instrument above the  exercise
price  of the option for as long as  the Portfolio's obligation as writer of the
option  continues.   The   Portfolios   may  only   write   options   that   are
    
 
                                       20
<PAGE>
   
"covered."  A  covered  call option  means  that  so long  as  the  Portfolio is
obligated as the writer of the option,  it will own (i) the underlying  security
or   instrument  subject  to  the  option  or  (ii)  securities  or  instruments
convertible or exchangeable without  the payment of  any consideration into  the
security or instrument subject to the option.
    
 
   
    By  writing (or selling) a  put option, a Portfolio  incurs an obligation to
buy the security or instrument underlying  the option from the purchaser of  the
put  at the option's exercise price at any time during the option period, at the
purchaser's election. Options written by a  Portfolio may be exercisable by  the
purchaser  only on a  specific date. A  Portfolio that has  written a put option
will earmark  or segregate  sufficient liquid  assets to  cover its  obligations
under the option.
    
 
   
    The  Portfolios may  engage in transactions  in options which  are traded on
recognized exchanges or  over-the-counter. There currently  are limited  options
markets  in  many  countries,  particularly  emerging  countries  such  as Latin
American countries, and the nature of the strategies adopted by the Adviser  and
the  extent to which those strategies are used will depend on the development of
such option markets. The  primary risks associated with  the use of options  are
(i)  imperfect correlation  between the  change in  market value  of investments
held, purchased or sold  by a Portfolio  and the prices  of options relating  to
such  investments; and (ii)  possible lack of  a liquid secondary  market for an
option.
    
 
    REPURCHASE AGREEMENTS.  Each Portfolio may enter into repurchase  agreements
with  brokers, dealers or  banks that meet the  credit guidelines established by
the Fund's Board of Directors. In  a repurchase agreement, the Portfolio buys  a
security  from a seller  that has agreed  to repurchase it  at a mutually agreed
upon date and price, reflecting the interest rate effective for the term of  the
agreement.  The term of these agreements is  usually from overnight to one week,
and never  exceeds one  year. Repurchase  agreements may  be viewed  as a  fully
collateralized  loan  of money  by the  Portfolio to  the seller.  The Portfolio
always receives securities with  a market value at  least equal to the  purchase
price  (including accrued interest) as collateral,  and this value is maintained
during the term  of the  agreement. If the  seller defaults  and the  collateral
value  declines, the Portfolio might incur a loss. If bankruptcy proceedings are
commenced with  respect to  the  seller, the  Portfolio's realization  upon  the
collateral  may  be  delayed  or  limited. The  Portfolios  may  not  enter into
repurchase agreements with  more than seven  days to maturity  if, as a  result,
more  than  15% of  the  market value  of the  Portfolio's  net assets  would be
invested in such repurchase agreements and in other investments for which market
quotations are not readily available or which are otherwise illiquid.
 
   
    REVERSE REPURCHASE  AGREEMENTS.   The Emerging  Markets Debt  Portfolio  may
enter  into reverse  repurchase agreements  with brokers,  dealers, domestic and
foreign  banks  or  other  financial  institutions.  In  a  reverse   repurchase
agreement,  the Portfolio  sells a  security and  agrees to  repurchase it  at a
mutually agreed upon date and price, reflecting the interest rate effective  for
the  term of the agreement. It  may also be viewed as  the borrowing of money by
the  Portfolio.  The  Portfolio's  investment  of  the  proceeds  of  a  reverse
repurchase  agreement is the speculative factor known as leverage. The Portfolio
may enter into a reverse repurchase  agreement only if the interest income  from
investment  of  the  proceeds  is  greater  than  the  interest  expense  of the
transaction and the proceeds are invested for  a period no longer than the  term
of  the agreement.  The Portfolio  will maintain  with the  Custodian a separate
account with a  segregated portfolio of  cash or other  liquid securities in  an
amount  at  least  equal to  its  purchase obligations  under  these agreements.
Reverse repurchase agreements are considered to be borrowings and are subject to
the percentage limitations on borrowings set forth in "Borrowing and Other Forms
of Leverage."
    
 
                                       21
<PAGE>
    RUSSIAN SECURITIES TRANSACTIONS.  The Emerging Markets Portfolio may  invest
in  equity  securities  of  Russian  issuers.  The  registration,  clearing  and
settlement of securities transactions in Russia are subject to significant risks
not normally associated with  securities transactions in  the United States  and
other  more  developed  markets. Ownership  of  shares in  Russian  companies is
evidenced by entries in a company's share register (except where shares are held
through depositories  that  meet the  requirements  of  the 1940  Act)  and  the
issuance  of extracts from the register or,  in certain limited cases, by formal
share certificates. However, Russian  share registers are frequently  unreliable
and  the  Portfolio  could  possibly lose  its  registration  through oversight,
negligence or fraud.  Moreover, Russia  lacks a centralized  registry to  record
securities   transactions  and  registrars  located  throughout  Russia  or  the
companies  themselves  maintain  share   registers.  Registrars  are  under   no
obligation  to provide extracts to potential purchasers in a timely manner or at
all and are not necessarily subject to effective state supervision. In addition,
while registrars are liable under law for losses resulting from their errors, it
may be difficult for the Portfolio to enforce any rights it may have against the
registrar  or  issuer  of  the  securities  in  the  event  of  loss  of   share
registration.  Although Russian companies with  more than 1,000 shareholders are
required by law to employ an independent company to maintain share registers, in
practice, such companies have not always followed this law. Because of this lack
of independence of registrars,  management of a Russian  company may be able  to
exert considerable influence over who can purchase and sell the company's shares
by  illegally instructing the registrar to  refuse to record transactions on the
share register.  Furthermore, these  practices may  prevent the  Portfolio  from
investing  in the securities of certain Russian companies deemed suitable by the
Adviser and  could cause  a  delay in  the sale  of  Russian securities  by  the
Portfolio  if the  company deems  a purchaser  unsuitable, which  may expose the
Portfolio to potential loss on its investment.
 
    In light  of  the risks  described  above, the  Board  of Directors  of  the
Portfolio has approved certain procedures concerning the Portfolio's investments
in  Russian  securities.  Among  these  procedures  is  a  requirement  that the
Portfolio will  not invest  in the  securities of  Russian issuers  unless  that
issuer's   registrar  has   entered  into   a  contract   with  the  Portfolio's
sub-custodian containing certain  protective conditions  including, among  other
things,  the  sub-custodian's right  to conduct  regular share  confirmations on
behalf of  the  Portfolio. This  requirement  will  likely have  the  effect  of
precluding  investments in  certain Russian  companies that  the Portfolio would
otherwise make.
 
    SHORT SALES.  The Emerging Markets Debt Portfolio may from time to time sell
securities short  without  limitation,  but  consistent  with  applicable  legal
requirements.  A  short  sale is  a  transaction  in which  the  Portfolio sells
securities it owns or has the right to acquire at no added cost (i.e.,  "against
the box") or does not own (but has borrowed) in anticipation of a decline in the
market  price of  the securities.  To deliver the  securities to  the buyer, the
Portfolio arranges through a broker to  borrow the securities and, in so  doing,
the  Portfolio becomes  obligated to  replace the  securities borrowed  at their
market price at the time of replacement. When the Portfolio makes a short  sale,
the  proceeds it receives from the sale will be held on behalf of a broker until
the Portfolio replaces the borrowed securities. The Portfolio may have to pay  a
premium  to borrow the securities and must pay any dividends or interest payable
on the securities until they are replaced.
 
   
    The Portfolio's obligation to replace the securities borrowed in  connection
with  a short sale will be secured  by collateral deposited with the broker that
consists of cash  or other liquid  securities. In addition,  the Portfolio  will
place  in a  segregated account with  its Custodian  an amount of  cash or other
liquid securities equal to the difference, if any, between (1) the market  value
of  the securities sold  at the time  they were sold  short and (2)  any cash or
other liquid securities deposited  as collateral with  the broker in  connection
with the short sale. Short
    
 
                                       22
<PAGE>
sales  by  the  Portfolio  involve  certain  risks  and  special considerations.
Possible losses from short sales differ from losses that could be incurred  from
a  purchase of  a security,  because losses from  short sales  may be unlimited,
whereas losses from purchases can equal only the total amount invested.
 
   
    STRUCTURED NOTES.  The Portfolios may invest in structured notes, which  are
derivatives  on which the amount of principal repayment and/or interest payments
is based upon the movement  of one or more  factors. These factors include,  but
are  not limited to, currency exchange rates,  interest rates (such as the prime
lending rate and LIBOR)  and stock indices  such as the S&P  500 Index. In  some
cases,  the impact of  the movements of  these factors may  increase or decrease
through the use of multipliers or deflators. The use of structured notes  allows
a  Portfolio to  tailor its  investments to the  specific risks  and returns the
Adviser wishes to accept while avoiding or reducing certain other risks.
    
 
    STRUCTURED SECURITIES.   The Emerging  Markets Debt Portfolio  may invest  a
portion  of its assets in entities organized and operated solely for the purpose
of restructuring the investment  characteristics of sovereign debt  obligations.
This type of restructuring involves the deposit with, or purchase by, an entity,
such  as a  corporation or trust,  of specified instruments  (such as commercial
bank loans  or Brady  Bonds) and  the issuance  by that  entity of  one or  more
classes  of  securities  ("Structured Securities")  backed  by,  or representing
interests in,  the  underlying instruments.  The  cash flow  on  the  underlying
instruments  may be apportioned among the  newly issued Structured Securities to
create securities  with different  investment characteristics,  such as  varying
maturities,  payment priorities and interest rate  provisions, and the extent of
the payments made  with respect  to Structured  Securities is  dependent on  the
extent  of the  cash flow  on the  underlying instruments.  Because the  type of
Structured  Securities  in  which  the  Portfolio  anticipates  it  will  invest
typically  involve no  credit enhancement, their  credit risk  generally will be
equivalent to that of the underlying instruments. The Portfolio is permitted  to
invest  in  a class  of  Structured Securities  that  is either  subordinated or
unsubordinated to the right of payment of another class. Subordinated Structured
Securities  typically  have  higher  yields  and  present  greater  risks   than
unsubordinated  Structured Securities. Certain  issuers of Structured Securities
may be deemed to be "investment companies" as defined in the 1940 Act and, as  a
result,  the Portfolio's investment  in Structured Securities  may be limited by
the 1940  Act. Structured  Securities are  typically sold  in private  placement
transactions,  and there  currently is no  active trading  market for Structured
Securities.
 
   
    SWAPS--SWAP CONTRACTS.    The Portfolios  may  invest in  Swaps,  which  are
derivatives  in the form of a contract  or other similar instrument in which two
parties agree to  exchange the returns  generated by a  security, instrument  or
basket thereof for the returns generated by another security, instrument, basket
thereof  or index. The payment streams are calculated by reference to a specific
security, index or instrument and an  agreed upon notional amount. The  relevant
indices include but are not limited to, currencies, fixed interest rates, prices
and  total return on interest rate  indices, fixed-income indices, stock indices
and commodity indices (as well as amounts derived from arithmetic operations  on
these  indices). For example, a Portfolio may agree to swap the return generated
by a fixed-income index for the return generated by a second fixed-income index.
The currency swaps in which the  Portfolios may enter will generally involve  an
agreement  to pay interest streams in one currency based on a specified index in
exchange for receiving  interest streams denominated  in another currency.  Such
swaps may involve initial and final exchanges that correspond to the agreed upon
notional amount.
    
 
   
    A  Portfolio will  usually enter into  swaps on  a net basis,  i.e., the two
return streams are netted out in a cash settlement on the payment date or  dates
specified  in the instrument, with a Portfolio  receiving or paying, as the case
may be, only the net amount of the two returns. A Portfolio's obligations  under
a swap agreement will be
    
 
                                       23
<PAGE>
   
accrued  daily  (offset against  any  amounts owing  to  the Portfolio)  and any
accrued but unpaid net amounts  owed to a swap  counterparty will be covered  by
the maintenance of a segregated account consisting of cash or liquid securities.
A Portfolio will not enter into any swap agreement unless the counterparty meets
the  rating requirements set forth in guidelines established by the Fund's Board
of Directors.
    
 
   
    Interest rate and total rate of return swaps do not involve the delivery  of
securities, other underlying assets, or principal. Accordingly, the risk of loss
with  respect to interest rate and total rate  of return swaps is limited to the
net amount of payments that a  Portfolio is contractually obligated to make.  If
the  other party to  an interest rate or  total rate of  return swap defaults, a
Portfolio's risk of loss consists of the net amount of payments that a Portfolio
is contractually entitled to  receive. In contrast,  currency swaps may  involve
the  delivery  of  the entire  principal  value  of one  designated  currency in
exchange for  the other  designated currency.  Therefore, the  entire  principal
value  of a currency swap may be subject to the risk that the other party to the
swap will default on its contractual delivery obligations. If there is a default
by the counterparty, a Portfolio may  have contractual remedies pursuant to  the
agreements  related to the transaction. The swap markets has grown substantially
in recent years with a large number of banks and investment banking firms acting
both as principals and as agents utilizing standardized swap documentation. As a
result, the swap market has become  relatively liquid. Swaps that include  caps,
floors   and  collars  are  more   recent  innovations  for  which  standardized
documentation has not yet been fully  developed and, accordingly, they are  less
liquid than swaps.
    
 
   
    The  use of swaps is a highly specialized activity which involves investment
techniques and risks  different from  those associated  with ordinary  portfolio
securities  transactions. If the Adviser is incorrect in its forecasts of market
values, interest rates, and currency exchange rates, the investment  performance
of  the  Portfolios would  be less  favorable than  it would  have been  if this
investment technique were not used.
    
 
   
    TEMPORARY INVESTMENTS.  For temporary  defensive purposes, when the  Adviser
determines  that market conditions warrant, each Portfolio may invest up to 100%
of its assets in dollar and non-dollar denominated money market instruments  and
short-  and medium-term debt securities that the  Adviser believes to be of high
quality, or hold  cash. The short-  and medium-term debt  securities in which  a
Portfolio  may invest consist of (a) obligations  of the U.S. or foreign country
governments, their respective agencies  or instrumentalities; (b) bank  deposits
and  bank  obligations (including  certificates  of deposit,  time  deposits and
bankers' acceptances)  of  U.S. or  foreign  country banks  denominated  in  any
currency;  (c) floating rate securities and other instruments denominated in any
currency issued by international development  agencies; (d) finance company  and
corporate  commercial paper and  other short-term corporate  debt obligations of
U.S. and foreign  country corporations  meeting the  Portfolio's credit  quality
standards;  and  (e) repurchase  agreements with  banks and  broker-dealers with
respect to such securities.
    
 
    WHEN-ISSUED AND DELAYED  DELIVERY SECURITIES.   Each Portfolio may  purchase
securities  on a  when-issued or delayed  delivery basis.  In such transactions,
instruments are bought with payment and  delivery taking place in the future  in
order  to secure what is considered to be  an advantageous yield or price at the
time of  the transaction.  Each Portfolio  will maintain  with the  Custodian  a
separate  account with a segregated portfolio of cash or other liquid securities
in an amount at least equal to these commitments. The payment obligation and the
interest rates that will be  received are each fixed  at the time the  Portfolio
enters  into  the commitment  and  no interest  accrues  to the  Portfolio until
settlement. Thus, it is possible that the market value at the time of settlement
could be higher or lower  than the purchase price  if, among other factors,  the
general level of interest
 
                                       24
<PAGE>
rates  has changed. It is  a current policy of each  Portfolio not to enter into
when-issued  commitments  or  delayed  delivery  securities  exceeding  in   the
aggregate  15%  of  the  market  value  of  the  Portfolio's  total  assets less
liabilities, other than the obligations created by these commitments.
 
                             INVESTMENT LIMITATIONS
 
    Each Portfolio  is a  non-diversified portfolio  under the  1940 Act,  which
means that the Portfolio is not limited by the 1940 Act in the proportion of its
assets  that may be invested  in the obligations of  a single issuer. Thus, each
Portfolio may invest a greater proportion of its total assets in the  securities
of a smaller number of issuers and, as a result, will be subject to greater risk
with  respect to its portfolio  securities. Nevertheless, each Portfolio intends
to comply  with the  more limited  diversification requirements  imposed by  the
Internal  Revenue Code of 1986, as amended  (the "Code"), for qualification as a
regulated investment company.
 
    Each Portfolio  operates  under  certain investment  restrictions  that  are
deemed  fundamental limitations and may be changed only with the approval of the
holders of a majority  of the Portfolio's outstanding  shares and under  certain
non-fundamental  investment limitations that may  be changed without shareholder
approval.  For  additional  information   on  fundamental  and   non-fundamental
investment  limitations,  see  "Investment  Limitations"  in  the  Statement  of
Additional Information.
 
                             MANAGEMENT OF THE FUND
 
    INVESTMENT ADVISER.  Morgan Stanley Asset Management Inc. is the Adviser and
Administrator of the Fund  and each Portfolio.  The Adviser provides  investment
advice  and portfolio  management services,  pursuant to  an Investment Advisory
Agreement and, subject  to the  supervision of  the Fund's  Board of  Directors,
makes  each of the Portfolio's day-to-day investment decisions, arranges for the
execution  of  portfolio  transactions  and   generally  manages  each  of   the
Portfolio's  investments. The Adviser is entitled to receive from each Portfolio
an annual management fee, payable quarterly, equal to the percentage of  average
daily  net assets set forth in the  table below. However, the Adviser has agreed
to a reduction  in the fees  payable to it  and to reimburse  the Portfolio,  if
necessary,  if  such fees  would cause  the total  annual operating  expenses of
either Portfolio  to exceed  the  respective percentages  of average  daily  net
assets set forth in the table below.
 
   
<TABLE>
<CAPTION>
                                                  MAXIMUM TOTAL ANNUAL
                                                        OPERATING
                                                   EXPENSES AFTER FEE
                                                         WAIVERS
                                  MANAGEMENT    -------------------------
          PORTFOLIO                   FEE        CLASS A         CLASS B
- ------------------------------    -----------   ---------       ---------
<S>                               <C>           <C>             <C>
Emerging Markets Portfolio             1.25%       1.75%           2.00%
Emerging Markets Debt
 Portfolio                             1.00%       1.75%           2.00%
</TABLE>
    
 
   
    The  Adviser, with  principal offices  at 1221  Avenue of  the Americas, New
York, New York  10020, conducts  a worldwide portfolio  management business  and
provides  a broad  range of  portfolio management  services to  customers in the
United States and  abroad. On February  5, 1997, Morgan  Stanley Group Inc.  and
Dean  Witter, Discover & Co.  announced that they had  entered into an Agreement
and Plan of Merger to  form Morgan Stanley, Dean  Witter, Discover & Co.  Morgan
Stanley  Group Inc.  is the  direct parent  of the  Adviser and  Morgan Stanley.
Subject to certain conditions  being met, it is  currently anticipated that  the
transaction  will close in mid-1997. Thereafter,  the Adviser and Morgan Stanley
will be subsidiaries of Morgan Stanley, Dean Witter, Discover & Co. At March 31,
1997, the  Adviser, together  with its  affiliated asset  management  companies,
    
 
                                       25
<PAGE>
   
managed  investments totaling in excess of $118 billion, including approximately
$100 billion  under active  management and  $18 billion  as Named  Fiduciary  or
Fiduciary  Adviser. See "Management of the  Fund" in the Statement of Additional
Information.
    
 
    PORTFOLIO MANAGERS.    The  following  individuals  have  primary  portfolio
management responsibility for the Portfolios noted below:
 
    EMERGING  MARKETS PORTFOLIO -- MADHAV DHAR AND MARIANNE L. HAY.  Madhav Dhar
is a Managing Director of Morgan Stanley. He joined the Adviser in 1984 to focus
on global asset allocation and investment strategy  and is now a co-head of  the
Adviser's  emerging markets  group. He holds  a B.S. (honors)  from St. Stephens
College,  Delhi  University   (India),  and  an   M.B.A.  from   Carnegie-Mellon
University. Mr. Dhar has had primary responsibility for managing the Portfolio's
assets since inception. Marianne L. Hay, a Managing Director of Morgan Stanley &
Co.  Incorporated,  is a  co-head of  the Adviser's  emerging markets  group and
shares, with  Mr.  Dhar, primary  responsibility  for managing  the  Portfolio's
assets.  She joined the Adviser  in June 1993 to  work with the Adviser's senior
management covering all emerging markets, asset aloocation, product  development
and  clients services. Ms. Hay  has 17 years of  investment experience. Prior to
joining the Adviser, she was a director of Martin Currie Investment  Management,
Ltd.  where  her  responsibilities  included  geographic  asset  allocation  and
portfolio management for  global and emerging  markets funds, as  well as  being
director  in charge  of the  company's North American  clients. Prior  to to her
tenure at Martin Currie Investment Management,  Ltd. she worked for the Bank  of
Scotland and the investment management firm of Ivory and Sime plc. She graduated
with  an honors degree in genetics from Edinburgh University and holds a Diploma
in Education  and the  qualification  of the  Association  of the  Institute  of
Bankers in Scotland.
 
    EMERGING  MARKETS  DEBT PORTFOLIO  --  PAUL GHAFFARI.    Paul Ghaffari  is a
Principal of  Morgan Stanley.  He joined  the Adviser  in June  1993 as  a  Vice
President  and Portfolio  Manager for the  Morgan Stanley  Emerging Markets Debt
Fund (a  closed-end  investment company).  Prior  to joining  the  Adviser,  Mr.
Ghaffari  was a  Vice President  in the  Fixed Income  Division of  the Emerging
Markets Sales and Trading  Department at Morgan Stanley.  From 1983 to 1992,  he
worked  in LDC Sales  and Trading Department  and the Mortgage-Backed Securities
Department at J.P. Morgan &  Co. Inc. and worked  in the Treasury Department  at
the  Morgan Guaranty Trust Co.  He holds a B.A.  in International Relations from
Pamona College and an  M.S. in Foreign Service  from Georgetown University.  Mr.
Ghaffari  has  had primary  responsibility for  managing the  Portfolio's assets
since inception.
 
    ADMINISTRATOR.  The  Adviser also  provides administrative  services to  the
Fund  pursuant to an  Administration Agreement. The  services provided under the
Administration Agreement are subject to the supervision of the Officers and  the
Board  of Directors of the Fund and include day-to-day administration of matters
related to the  corporate existence  of the  Fund, maintenance  of its  records,
preparation  of  reports,  supervision  of  the  Fund's  arrangements  with  its
custodian  and  assistance  in  the  preparation  of  the  Fund's   registration
statements  under federal laws. The  Administration Agreement also provides that
the Administrator,  through its  agents, will  provide dividend  disbursing  and
transfer  agent services to the Fund.  For its services under the Administration
Agreement, the Fund  pays the Adviser  a monthly  fee which on  an annual  basis
equals 0.15% of the average daily net assets of each Portfolio.
 
                                       26
<PAGE>
   
    Under  an  agreement  between  the  Adviser  and  The  Chase  Manhattan Bank
("Chase"), Chase provides  certain administrative services  to the Fund  through
its  corporate  affiliate, Chase  Global Funds  Services Company  ("CGFSC"). The
Adviser supervises and monitors administrative services provided by CGFSC. Their
services are also subject to  the supervision of the  Board of Directors of  the
Fund.  CGFSC's  business address  is  73 Tremont  Street,  Boston, Massachusetts
02108-3913.
    
 
    LOCAL ADMINISTRATORS FOR THE EMERGING MARKETS PORTFOLIO.  The Portfolio has,
as required  by local  law, entered  into administration  agreements with  local
administrators  in Brazil and  Colombia. A local  administrator provides certain
services for the Portfolio with respect  to the Portfolio's investments in  that
country,   including  services  relating  to   foreign  exchange,  local  taxes,
remittance of income  and capital  gains, and repatriation  of investments.  The
Portfolio's   local  administrator   in  Brazil,   Unibanco-Uniao,  a  Brazilian
corporation, is  paid by  an annual  fee of  0.125% of  the Portfolio's  average
weekly  net assets  invested in Brazil.  The Portfolio's  local administrator in
Colombia, CitiTrust S.A.,  a Colombian  trust company, is  paid by  the Fund  an
annual fee of $1,000 plus 0.20% per transaction in Colombia.
 
    DIRECTORS  AND OFFICERS.  Pursuant to  the Fund's Articles of Incorporation,
the Board of Directors  decides upon matters of  general policy and reviews  the
actions  of  the Fund's  Adviser, Administrator,  Distributor and  other service
providers. The Officers  of the Fund  conduct and supervise  its daily  business
operations.
 
    DISTRIBUTOR.   Morgan  Stanley serves  as the  exclusive Distributor  of the
shares of  the Fund.  Under its  Distribution Agreement  with the  Fund,  Morgan
Stanley  sells  shares of  each  Portfolio upon  the  terms and  at  the current
offering price described in this Prospectus. Morgan Stanley is not obligated  to
sell any certain number of shares of any Portfolio.
 
    The  Portfolios currently offer  only the classes of  shares offered by this
Prospectus. The Portfolio may in the future offer one or more classes of  shares
with  features, distribution expenses or other  expenses that are different from
those of the classes currently offered.
 
    The Fund has  adopted a Plan  of Distribution  with respect to  the Class  B
shares  for each Portfolio  pursuant to Rule  12b-1 under the  1940 Act (each, a
"Plan"). Under  each Plan,  the  Distributor is  entitled  to receive  from  the
Portfolios  a distribution  fee, which is  accrued daily and  paid quarterly, of
0.25% of the Class B  shares' average daily net  assets on an annualized  basis.
The  Distributor  expects  to  reallocate  most of  its  fee  to  its investment
representatives. The Distributor may, in its discretion, voluntarily waive  from
time  to  time all  or  any portion  of  its distribution  fee  and each  of the
Distributor and the Adviser is free to  make additional payments out of its  own
assets  to promote the  sale of Fund shares,  including payments that compensate
financial institutions for distribution services or shareholder services.
 
    Each Plan is designed to compensate the Distributor for its services, not to
reimburse the Distributor for its expenses,  and the Distributor may retain  any
portion  of the fee that it does not expend in fulfillment of its obligations to
the Fund.
 
    PAYMENTS TO  FINANCIAL INSTITUTIONS.    The Adviser  or its  affiliates  may
compensate  certain financial institutions for the continued investment of their
customers' assets in the  Emerging Markets Portfolio pursuant  to the advice  of
such financial institutions. These payments will be made directly by the Adviser
or its affiliates from their assets, and will not be made from the assets of the
Fund    or    by   the    assessment   of    a    sales   charge    on   shares.
 
                                       27
<PAGE>
Such  financial   institutions  may   also   perform  certain   shareholder   or
recordkeeping  services that would otherwise be  performed by CGFSC. The Adviser
may elect to enter into  a contract to pay  the financial institutions for  such
services.
 
    EXPENSES.   Each Portfolio is responsible  for payment of certain other fees
and expenses  (including organizational  costs, legal  fees, accountant's  fees,
custodial  fees, and printing and mailing costs) specified in the Administration
and Distribution Agreements.
 
                               PURCHASE OF SHARES
 
    Class A and Class  B shares of  each Portfolio may be  purchased at the  net
asset value per share next determined after receipt of the purchase order by the
Portfolio. See "Valuation of Shares."
 
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
 
    For  a  Portfolio  account  opened  on or  after  January  2,  1996  (a "New
Account"), the minimum initial investment and minimum account size are  $500,000
for  Class A shares and  $100,000 for Class B  shares of each Portfolio. Certain
advisory or asset allocation accounts, such as Total Funds Management  accounts,
managed  by Morgan  Stanley or its  affiliates, including  the Adviser ("Managed
Accounts") may purchase  Class A  shares without  being subject  to any  minimum
initial investment or minimum account size requirements for a Portfolio account.
Employees  of the  Adviser and  certain of its  affiliates may  purchase Class A
Shares subject  to conditions,  including a  lower minimum  initial  investment,
established by Officers of the Fund.
 
    If  the  value of  a  New Account,  containing  Class A  shares  falls below
$500,000  (but   remains  at   or  above   $100,000)  because   of   shareholder
redemption(s),  the Fund will  notify the shareholder, and  if the account value
remains below  $500,000 (but  remains at  or above  $100,000) for  a  continuous
60-day period, the Class A shares in such account will convert to Class B shares
and will be subject to the distribution fee and other features applicable to the
Class  B shares. The Fund,  however, will not convert Class  A shares to Class B
shares based solely upon changes in the  market that reduce the net asset  value
of  shares. Under current tax  law, conversions between share  classes are not a
taxable event to the shareholder.
 
    Shares in a Portfolio account opened  prior to January 2, 1996 (a  "Pre-1996
Account")  were  designated Class  A  shares on  January  2, 1996.  Shares  in a
Pre-1996 Account  with  a  value  of  $100,000 or  more  on  March  1,  1996  (a
"Grandfathered  Class A Account") remained Class  A shares regardless of account
size thereafter. Except for  shares in a Managed  Account, shares in a  Pre-1996
Account  with a value of  less than $100,000 on  March 1, 1996 (a "Grandfathered
Class B Account") converted  to Class B shares  on March 1, 1996.  Grandfathered
Class A Accounts and Managed Accounts are not subject to conversion from Class A
shares to Class B shares.
 
    Investors  may also invest in the Fund  by purchasing shares through a trust
department, broker, dealer, agent, financial planner, financial services firm or
investment adviser.  An  investor  may  be  charged  an  additional  service  or
transaction fee by that institution.
 
   
    The minimum investment levels may be waived at the discretion of the Adviser
for  (i) certain employees and customers of Morgan Stanley or its affiliates and
certain  trust  departments,  brokers,   dealers,  agents,  financial   planers,
financial  services  firms  or investment  advisers  that have  entered  into an
agreement with  Morgan  Stanley  or  its affiliates;  and  (ii)  retirement  and
deferred compensation plans and trusts, used to fund
    
 
                                       28
<PAGE>
such  plans, including,  but not  limited to,  those defined  in Section 401(a),
403(b) or 457 of  the Code and  "rabbi trusts". The Fund  reserves the right  to
modify or terminate the conversion features of the shares as stated above at any
time upon 60-days notice to shareholders.
 
    The  Adviser reserves the right in its sole discretion to determine which of
such advisory  or  asset aloocation  accounts  shall be  Managed  Accounts.  For
information  regarding  Managed  Accounts, please  contact  your  Morgan Stanley
account representative or the Fund at the telephone number provided on the cover
of this Prospectus.
 
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
 
    If the value of  a New Account falls  below $100,000 because of  shareholder
redemption(s),  the Fund will  notify the shareholder, and  if the account value
remains below  $100,000 for  a  continuous 60-day  period,  the shares  in  such
account  are subject to redemption  by the Fund and,  if redeemed, the net asset
value of  such  shares will  be  promptly paid  to  the shareholder.  The  Fund,
however,  will not redeem  shares based solely  upon changes in  the market that
reduce the net asset value of shares.
 
    Grandfathered Class A Accounts, Grandfathered  Class B Accounts and  Managed
Accounts  are not subject to involuntary redemption. The Fund reserves the right
to modify or  terminate the  involuntary redemption  features of  the shares  as
stated above at any time upon 60-days notice to shareholders.
 
CONVERSION FROM CLASS B TO CLASS A SHARES
 
    If the value of Class B shares in a Portfolio account increases, whether due
to  shareholder share  purchases or  market activity,  to $500,000  or more, the
Class B shares  will convert  to Class  A shares.  Under current  tax law,  such
conversion  is not a taxable event to  the shareholder. Class A shares converted
from Class B shares  are subject to the  same minimum account size  requirements
that  are applicable to New Accounts containing Class A shares, as stated above.
The Fund reserves the  right to modify or  terminate this conversion feature  at
any time upon 60-days notice to shareholders.
 
INITIAL PURCHASES DIRECTLY FROM THE FUND
 
    The  Fund's determination of an investor's eligibility to purchase shares of
a given class  will take precedence  over the investor's  selection of a  class.
Assuming  the investor is eligible for the  class, the Fund will select the most
favorable class for the investor, if the investor has not done so.
 
1) BY CHECK.   An account may  be opened  by completing and  signing an  Account
   Registration  Form, and mailing  it, together with  a check ($500,000 minimum
   for Class A shares of each Portfolio and $100,000 minimum for Class B  shares
   of  each Portfolio, with certain exceptions  for Morgan Stanley employees and
   select customers)  payable to  "Morgan Stanley  Institutional Fund,  Inc.  --
   [portfolio name]", to:
 
      Morgan Stanley Institutional Fund, Inc.
      P.O. Box 2798
      Boston, Massachusetts 02208-2798
 
     Payment will  be accepted only  in U.S. dollars,  unless prior approval for
  payment by other currencies is given by the Fund. The classes of shares of the
  Portfolio(s)   to    be    purchased    should   be    designated    on    the
 
                                       29
<PAGE>
  Account  Registration Form.  For purchases  by check,  the Fund  is ordinarily
  credited with Federal Funds  within one business day.  Thus, your purchase  of
  shares  by check is ordinarily credited to your account at the net asset value
  per share of each of the Portfolios determined on the next business day  after
  receipt.
 
2) BY  FEDERAL  FUNDS WIRE.   Purchases  may be  made by  having your  bank wire
   Federal Funds to the Fund's bank  account. In order to ensure prompt  receipt
   of your Federal Funds Wire, it is important that you follow these steps:
 
A.   Telephone  the Fund  (toll free: 1-800-548-7786)  and provide  us with your
    name, address,  telephone  number,  Social Security  or  Tax  Identification
    Number,  the  portfolio(s) selected,  the class  selected, the  amount being
    wired, and by  which bank.  We will  then provide  you with  a Fund  account
    number.  (Investors with existing accounts should also notify the Fund prior
    to wiring funds.)
 
B.   Instruct  your  bank to  wire  the  specified amount  to  the  Fund's  Wire
    Concentration  Bank Account (be sure  to have your bank  include the name of
    the portfolio(s)  selected,  the  class  selected  and  the  account  number
    assigned to you) as follows:
 
   
    The Chase Manhattan Bank
    One Manhattan Plaza
    New York, NY 10081-1000
    ABA#021000021
    DDA# 910-2-733293
    Attn: Morgan Stanley Institutional Fund, Inc.
    Ref: (Portfolio name, your account number, your account name)
    
 
    Please call the Fund at 1-800-548-7786 prior to wiring funds.
 
C.   Complete and sign the Account Registration  Form and mail it to the address
    shown thereon.
 
    The purchase price of the  Class A and Class B  shares of the Portfolios  is
    the  net  asset  value next  determined  after  the order  is  received. See
    "Valuation of Shares." An order received  prior to the regular close of  the
    New York Stock Exchange ("NYSE"), which is currently 4:00 p.m. Eastern Time,
    will  be executed  at the price  computed on  the date of  receipt; an order
    received after the regular close of the  NYSE will be executed at the  price
    computed  on the  next day the  NYSE is open  as long as  the Transfer Agent
    receives payment by check or in Federal Funds prior to the regular close  of
    the NYSE on such day.
 
    Federal  Funds purchase orders will  be accepted only on  a day on which the
    Fund and Chase (the "Custodian Bank")  are open for business. Your bank  may
    charge a service fee for wiring Federal funds.
 
3) BY  BANK WIRE.   The  same procedure outlined  under "By  Federal Funds Wire"
   above must be  followed in  purchasing shares  by bank  wire. However,  money
   transferred  by bank wire may or may  not be converted into Federal Funds the
   same day, depending on the time the  money is received and the bank  handling
   the wire. Prior to such conversion, an investor's money will not be invested.
   Your bank may charge a service fee for wiring funds.
 
                                       30
<PAGE>
ADDITIONAL INVESTMENTS
 
    You  may  add to  your account  at any  time (minimum  additional investment
$1,000 for each portfolio,  except for automatic  reinvestment of dividends  and
capital  gains  distributions for  which there  are  no minimums)  by purchasing
shares at net asset  value by mailing  a check to the  Fund (payable to  "Morgan
Stanley  Institutional Fund, Inc. -- [portfolio  name]") at the above address or
by wiring monies to the Custodian Bank  as outlined above. It is very  important
that  your account name, the portfolio name  and the class selected be specified
in the letter or wire  to assure proper crediting to  your account. In order  to
ensure  that your wire orders are invested promptly, you are requested to notify
one of the Fund's representatives (toll free: 1-800-548-7786) prior to the  wire
date.  Additional investments will  be applied to  purchase additional shares in
the same class held by a shareholder in a Portfolio account.
 
OTHER PURCHASE INFORMATION
 
    Although the legal rights of Class A  and Class B shares will be  identical,
the  different expenses borne by  each class will result  in different net asset
values and dividends. The net  asset value of Class  B shares will generally  be
lower than the net asset value of Class A shares as a result of the distribution
expense  charged to Class B shares. It  is expected, however, that the net asset
value per share of the two classes  will tend to converge immediately after  the
recording  of dividends  which will  differ by  approximately the  amount of the
distribution expense accrual differential between the classes.
 
    In the interest  of economy and  convenience, and because  of the  operating
procedures  of the  Fund, certificates  representing shares  of the Portfolio(s)
will not be issued. All  shares purchased are confirmed  to you and credited  to
your  account on the Fund's  books maintained by the  Adviser or its agents. You
will have  the same  rights and  ownership with  respect to  such shares  as  if
certificates had been issued.
 
    To  ensure that checks are collected by the Fund, withdrawals of investments
made by check  are not presently  permitted until payment  for the purchase  has
been  received,  which may  take up  to eight  business days  after the  date of
purchase. As a  condition of this  offering, if  a purchase is  canceled due  to
nonpayment or because your check does not clear, you will be responsible for any
loss  the Fund or its  agents incur. If you are  already a shareholder, the Fund
may redeem shares from your account(s) to  reimburse the Fund or its agents  for
any  loss. In addition, you  may be prohibited or  restricted from making future
purchases in the Fund.
 
    Investors may  also invest  in the  Fund by  purchasing shares  through  the
Distributor.
 
EXCESSIVE TRADING
 
    Frequent   trades  involving  either  substantial   portfolio  assets  or  a
substantial portion of your  account or accounts controlled  by you can  disrupt
management  of a portfolio and raise its expenses. Consequently, in the interest
of all the stockholders of each  Portfolio and the Portfolios' performance,  the
Fund  may in its discretion bar a  stockholder that engages in excessive trading
of shares of any class  of a portfolio from further  purchases of shares of  the
Fund  for an indefinite period. The Fund  considers excessive trading to be more
than one purchase and sale involving shares of the same class of a portfolio  of
the  Fund  within  any  120-day  period. As  an  example,  exchanging  shares of
portfolios of  the Fund  as  follows amounts  to excessive  trading:  exchanging
shares  of Portfolio  A for  shares of  Portfolio B,  then exchanging  shares of
Portfolio B for shares of Portfolio C and again exchanging shares of Portfolio C
for shares of Portfolio B within a 120-day period. Two types of transactions are
 
                                       31
<PAGE>
   
exempt from these excessive trading restrictions: (1) trades exclusively between
money market  portfolios;  and (2)  trades  done  in connection  with  an  asset
allocation  service, such as TFM Accounts or  accounts managed or advised by the
Adviser and/or any of its affiliates.
    
 
INVESTMENT IN FUNDS THROUGH A TOTAL FUNDS MANAGEMENT ("TFM") ACCOUNT
 
   
    In addition to the considerable diversification among individual  securities
you  receive by investing in a particular Portfolio, you can further reduce risk
by spreading  your assets  among  several different  Portfolios that  each  have
different   risk  and  return  characteristics.  TFM  is  an  active  investment
management service managed by Morgan Stanley or its affiliates, including Morgan
Stanley Asset  Management Inc.  (each,  a "TFM  Adviser"), that  allocates  your
investments  across a combination of either Class A or Class B shares of certain
of the Portfolios selected to meet your long-term investment objectives as  well
as, in certain circumstances, your current income objectives.
    
 
   
    The TFM Adviser has developed investment strategies for TFM Accounts to meet
the  diverse financial needs of different investors.  You can open a TFM Account
by meeting with one  of the investment professionals  of a Participating  Dealer
who  will review your situation and  help you identify your long-term investment
and/or current income  objectives. After  using TFM criteria  to determine  your
long-term  investment and/or  current income objectives,  you can  choose one of
several TFM investment strategies. Based  on your chosen strategy, your  initial
investment  will be allocated among a number of the Class A or Class B shares of
the Portfolios. Depending  on market  conditions, the  TFM Adviser  periodically
reallocates  the combination of Portfolios or the percentage amounts invested in
the shares  of each  Portfolio to  implement your  TFM investment  strategy.  In
addition,  your TFM Account will be periodically rebalanced to maintain your TFM
strategy's current asset allocation mix, if  and when the performance of one  or
more  of the  Portfolios unbalances  the strategy's  mix. You  will pay  the TFM
Adviser a fee for the  TFM Account service that is  in addition to and  separate
from the fees and expenses you will pay directly or indirectly as an investor in
the Portfolios. See "Fund Expenses."
    
 
   
    From  time to time, one or more of the Portfolios used for investment by the
TFM Accounts may experience relatively  large investments or redemptions due  to
the  TFM Account  allocations or  rebalancings recommended  by the  TFM Adviser.
These transactions will affect the Portfolios, since Portfolios that  experience
redemptions  as  a result  of  reallocations or  rebalancings  may have  to sell
portfolio securities and Portfolios  that receive additional  cash will have  to
invest  it in additional portfolio securities. While it is impossible to predict
the overall  impact of  these transactions  over time,  there could  be  adverse
effects on portfolio management to the extent that Portfolios may be required to
sell  securities or invest  cash at times  when they would  not otherwise do so.
These transactions  could also  have  tax consequences  if sales  of  securities
resulted  in  gains  and could  also  increase transaction  costs.  The Adviser,
representing the interests  of the  Portfolios, is committed  to minimizing  the
impact of TFM Account transactions on the Portfolios. The Adviser, however, will
have  a conflict in fulfilling  this responsibility in that  it also serves as a
TFM Adviser. In that  capacity, the Adviser, representing  the interests of  the
TFM  Accounts,  also  is  committed  to minimizing  the  impact  of  TFM Account
transactions on  the  Portfolios to  the  extent consistent  with  pursuing  the
investment  objectives of the TFM Accounts. In addition, an affiliate of the TFM
Adviser, the Distributor is compensated on  the sale,and may be compensated  for
distribution  or shareholder services  on the sale of  shares of the Portfolios.
See "Purchase of Shares"  and "Shareholder Services  -- Exchange Features."  The
Adviser will monitor the impact of TFM Account transactions on the Portfolios.
    
 
                                       32
<PAGE>
                              REDEMPTION OF SHARES
 
    You  may  withdraw all  or  any portion  of the  amount  in your  account by
redeeming shares at any time. Please note  that purchases made by check are  not
permitted to be redeemed until payment of the purchase price has been collected,
which  may take up to  eight business days after  purchase. The Fund will redeem
Class A shares or Class  B shares of each Portfolio  at the next determined  net
asset  value of shares of  the applicable class. On days  that both the NYSE and
the Custodian Bank are open for business, the net asset value per share of  each
of  the Portfolios  is determined at  the regular  close of trading  of the NYSE
(currently 4:00 p.m. Eastern Time). Shares of the Portfolios may be redeemed  by
mail or telephone. No charge is made for redemption. Any redemption proceeds may
be more or less than the purchase price of your shares depending on, among other
factors, the market value of the investment securities held by the Portfolio.
 
BY MAIL
 
    Each  Portfolio will redeem its  Class A or Class B  shares at the net asset
value determined on the date the request is received, if the request is received
in "good order" before  the regular close  of the NYSE.  Your request should  be
addressed  to Morgan  Stanley Institutional Fund,  Inc., P.O.  Box 2798, Boston,
Massachusetts 02208-2798, except that deliveries by overnight courier should  be
addressed  to Morgan  Stanley Institutional Fund,  Inc., c/o  Chase Global Funds
Services Company, 73 Tremont Street, Boston, Massachusetts 02108-3913.
 
    "Good order"  means that  the  request to  redeem  shares must  include  the
following documentation:
 
         (a)  A letter of instruction or a stock assignment specifying the class
    and number  of  shares  or dollar  amount  to  be redeemed,  signed  by  all
    registered  owners  of the  shares  in the  exact  names in  which  they are
    registered;
 
        (b)  Any  required   signature  guarantees   (see  "Further   Redemption
    Information" below); and
 
         (c)  Other  supporting legal  documents, if  required,  in the  case of
    estates, trusts,  guardianships, custodianships,  corporations, pension  and
    profit sharing plans and other organizations.
 
    Shareholders who are uncertain of requirements for redemption should consult
with a Fund representative.
 
BY TELEPHONE
 
    Provided  you have previously elected the Telephone Redemption Option on the
Account Registration  Form, you  can  request a  redemption  of your  shares  by
calling  the Fund  and requesting  the redemption proceeds  be mailed  to you or
wired to your bank. Please contact one of the Fund's representatives for further
details. In times of drastic market conditions, the telephone redemption  option
may  be  difficult  to  implement.  If you  experience  difficulty  in  making a
telephone redemption, your request may be made by mail or express mail and  will
be  implemented at  the net  asset value next  determined after  it is received.
Redemption requests sent to the Fund through express mail must be mailed to  the
address  of the  Dividend Disbursing  and Transfer  Agent listed  under "General
Information." The Fund and the Fund's transfer agent (the "Transfer Agent") will
employ reasonable procedures  to confirm that  the instructions communicated  by
telephone  are  genuine.  These  procedures include  requiring  the  investor to
provide certain personal identification  information at the  time an account  is
opened  and  prior  to effecting  each  transaction requested  by  telephone. In
addition, all telephone transaction requests will be recorded and investors  may
be    required   to   provide   additional   telecopied   written   instructions
 
                                       33
<PAGE>
regarding transaction requests. Neither the Fund nor the Transfer Agent will  be
responsible  for any loss, liability, cost or expense for following instructions
received by telephone that either of them reasonably believes to be genuine.
 
    To change the commercial  bank or account  designated to receive  redemption
proceeds,  a written  request must  be sent  to the  Fund at  the address above.
Requests to change the bank  or account must be  signed by each shareholder  and
each signature must be guaranteed.
 
FURTHER REDEMPTION INFORMATION
 
    Normally  the  Fund will  make payment  for all  shares redeemed  within one
business day of receipt  of the request,  but in no event  will payment be  made
more  than  seven days  after receipt  of  a redemption  request in  good order.
However, payments to investors  redeeming shares which  were purchased by  check
will  not be made until  payment for the purchase  has been collected, which may
take up to eight days after the date of purchase. The Fund may suspend the right
of redemption or postpone the date upon which redemptions are effected at  times
when  the NYSE is closed, or under  any emergency circumstances as determined by
the Securities and Exchange Commission (the "Commission").
 
    If the Board  of Directors determines  that it would  be detrimental to  the
best  interests of  the remaining  shareholders of  a Portfolio  to make payment
wholly or partly in cash, the Fund  may pay the redemption proceeds in whole  or
in part by a distribution in-kind of securities held by the Portfolio in lieu of
cash    in    conformity   with    applicable    rules   of    the   Commission.
Distributions-in-kind will be made  in readily marketable securities.  Investors
may  incur brokerage charges on the sale  of portfolio securities so received in
payment of redemptions.
 
    To protect  your account,  the Fund  and its  agents from  fraud,  signature
guarantees  are required for  certain redemptions to verify  the identity of the
person who has  authorized a redemption  from your account.  Please contact  the
Fund  for further  information. See "Redemption  of Shares" in  the Statement of
Additional Information.
 
                              SHAREHOLDER SERVICES
 
EXCHANGE FEATURES
 
    You may exchange shares that you own  in either portfolio for shares of  any
other  available portfolio(s) of  the Fund (other  than the International Equity
Portfolio, which is  closed to  new investors). In  exchanging for  shares of  a
portfolio  with more  than one  class, the  class of  shares you  receive in the
exchange will be determined in the same  manner as any other purchase of  shares
and  will not  be based  on the  class of  shares surrendered  for the exchange.
Consequently, the same minimum initial  investment and minimum account size  for
determining  the  class  of shares  received  in  the exchange  will  apply. See
"Purchase of Shares" above. Shares of the portfolios may be exchanged by mail or
telephone. The privilege to exchange shares  by telephone is automatic and  made
available  without shareholder election. Before you make an exchange, you should
read the prospectus of the portfolio(s) in which you seek to invest. Because  an
exchange  transaction  is treated  as a  redemption followed  by a  purchase, an
exchange would be considered  a taxable event for  shareholders subject to  tax.
The  exchange privilege may  be modified or  terminated by the  Fund at any time
upon 60-days notice to shareholders.
 
                                       34
<PAGE>
BY MAIL
 
    In order to  exchange shares  by mail, you  should include  in the  exchange
request  the name, class of shares and account number of your current Portfolio,
the names of the portfolio(s) and class(es)  of shares into which you intend  to
exchange  shares, and the signatures of all registered account holders. Send the
exchange request  to Morgan  Stanley Institutional  Fund, Inc.,  P.O. Box  2798,
Boston, Massachusetts 02208-2798.
 
BY TELEPHONE
 
   
    When  exchanging shares by  telephone, have ready the  name, class of shares
and account number of  your current portfolio, the  name(s) of the  portfolio(s)
and  class(es) of shares into  which you intend to  exchange shares, your Social
Security number  or Tax  I.D. number,  and your  account address.  Requests  for
telephone  exchanges received prior to 4:00 p.m. (Eastern Time) are processed at
the close of business that same day based on the net asset value of the class of
each of  the portfolios  involved in  the exchange  of shares  at the  close  of
business.  Requests received  after 4:00 p.m.  (Eastern Time)  are processed the
next business  day based  on the  net asset  value determined  at the  close  of
business  on such day.  For additional information  regarding responsibility for
the authenticity of  telephoned instructions,  see "Redemption of  Shares --  By
Telephone" above.
    
 
TRANSFER OF REGISTRATION
 
    You may transfer the registration of any of your Portfolio shares to another
person  by writing  to Morgan  Stanley Institutional  Fund Inc.,  P.O. Box 2798,
Boston, Massachusetts 02208-2798.  As in  the case of  redemptions, the  written
request  must  be  received in  good  order  before any  transfer  can  be made.
Transferring the  registration of  shares  may affect  the eligibility  of  your
account  for  a  given  class  of each  Portfolio's  shares  and  may  result in
involuntary conversion or redemption  of your shares.  See "Purchase of  Shares"
above.
 
                              VALUATION OF SHARES
 
   
    The  net asset  value per share  of a class  of shares of  the Portfolios is
determined by dividing the total market value of the Portfolio's investments and
other assets attributable to  such class, less  any liabilities attributable  to
such  class, by  the total  number of  outstanding shares  of such  class of the
Portfolio. Net  asset value  is  calculated separately  for  each class  of  the
Portfolio.  Net asset value per  share is determined as  of the regular close of
the NYSE on each day  that the NYSE is open  for business. Price information  on
listed  securities is  taken from the  exchange where the  security is primarily
traded. Securities  listed  on  a  U.S. securities  exchange  for  which  market
quotations are available are valued at the last quoted sale price on the day the
valuation  is made. Securities listed on a  foreign exchange are valued at their
closing price.  Unlisted securities  and  listed securities  not traded  on  the
valuation date for which market quotations are readily available are valued at a
price  within a range  not exceeding the  current asked price  nor less than the
current bid price. The current bid and asked prices are determined based on  the
average  of the bid and asked prices  quoted on such valuation date by reputable
brokers.
    
 
    Bonds and other fixed income securities are valued according to the broadest
and most representative  market, which will  ordinarily be the  over-the-counter
market.  Net asset value includes interest  on fixed income securities, which is
accrued daily.  In addition,  bonds and  other fixed  income securities  may  be
valued on the basis of prices provided by a pricing service when such prices are
believed  to  reflect  the fair  market  value  of such  securities.  The prices
provided by a pricing service are determined without regard to bid or last  sale
prices,  but take into account institutional  size, trading in similar groups of
securities and any developments related to the
 
                                       35
<PAGE>
specific securities. Securities not priced in this manner are valued at the most
recently quoted bid price, or when  securities exchange valuations are used,  at
the  latest quoted  sale price  on the  day of  valuation. If  there is  no such
reported sale, the latest  quoted bid price will  be used. Securities  purchased
with remaining maturities of 60 days or less are valued at amortized cost, if it
approximates market value. In the event that amortized cost does not approximate
market value, market prices as determined above will be used.
 
   
    The  value  of other  assets  and securities  for  which quotations  are not
readily available  (including restricted  and unlisted  foreign securities)  and
those  securities  for  which  it  is  inappropriate  to  determined  prices  in
accordance with the above-stated procedures are determined in good faith at fair
value using  methods determined  by  the Board  of  Directors. For  purposes  of
calculating  net asset  value per  share, all  assets and  liabilities initially
expressed in foreign currencies will be translated into U.S. dollars at the mean
of the bid  and asked  price of  such currencies  against the  U.S. dollar  last
quoted by any major bank.
    
 
    Although  the legal rights of Class A  and Class B shares will be identical,
the different expenses borne  by each class will  result in different net  asset
values  and dividends for the class.  Dividends will differ by approximately the
amount of the distributions expense accrual differential among the classes.  The
net  asset value of  Class B shares will  generally be lower  than the net asset
value of the Class A shares as  a result of the distribution expense charged  to
Class B shares.
 
                            PERFORMANCE INFORMATION
 
    The  Fund may from time to time advertise the total return for each class of
the Portfolios.  THESE FIGURES  ARE BASED  ON HISTORICAL  EARNINGS AND  ARE  NOT
INTENDED TO INDICATE FUTURE PERFORMANCE.
 
    "Total  return" shows what an  investment in a class  of the Portfolio would
have earned over a specified  period of time (such as  one, five or ten  years),
assuming  that all distributions and dividends  by the Portfolio were reinvested
in the same class on the reinvestment dates during the period. Total return does
not take into account any federal or  state income taxes that may be payable  on
dividends  and  distributions  or upon  redemption.  The Fund  may  also include
comparative performance information in advertising or marketing the  Portfolios'
shares,  including data  from Lipper  Analytical Services,  Inc., other industry
publications, business periodicals, rating services and market indices.
 
    The performance figures  for Class  B shares  will generally  be lower  than
those  for Class  A shares because  of the  distribution fee charged  to Class B
shares.
 
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
 
    All income dividends and capital gains  distributions for a class of  shares
will be automatically reinvested in additional shares at net asset value, except
that,  upon written notice to the Fund or by checking off the appropriate box in
the Distribution Option Section on the Account Registration Form, a  shareholder
may elect to receive income dividends and capital gains distributions in cash.
 
   
    Each  Portfolio expects to  distribute substantially all  of its taxable net
investment income in the form of annual dividends. Net realized capital gains of
each Portfolio, if any, after reduction for any tax loss carryforwards will also
be distributed annually.
    
 
                                       36
<PAGE>
    Undistributed net  investment income  is included  in each  Portfolio's  net
assets  for the purpose of calculating net  asset value per share. Therefore, on
the "ex-dividend" date,  the net  asset value  per share  excludes the  dividend
(I.E.,  is reduced  by the  per share  amount of  the dividend).  Dividends paid
shortly after the purchase of shares by an investor, although in effect a return
of capital, are taxable to shareholders subject to income tax.
 
    Because of  the  distribution  fee  and  any  other  expenses  that  may  be
attributable  to the  Class B  shares, the  net income  attributable to  and the
dividends payable  on  Class  B  shares  will  be  lower  than  the  net  income
attributable  to and the dividends  payable on Class A  shares. As a result, the
net asset value per share of the classes of each Portfolio will differ at times.
Expenses of each  Portfolio allocated to  a particular class  of shares will  be
borne on a pro rata basis by each outstanding share of that class.
 
                                     TAXES
 
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
 
    No  attempt has been made to present  a detailed explanation of the federal,
state, or  local  income tax  treatment  of  a Portfolio  or  its  shareholders.
Accordingly,  shareholders  are urged  to consult  their tax  advisors regarding
specific questions as to federal, state and local income taxes.
 
    Each Portfolio  is treated  as  a separate  entity  for federal  income  tax
purposes  and is not  combined with the Fund's  other portfolios. Each Portfolio
intends to qualify for the  special tax treatment afforded regulated  investment
companies under Subchapter M of the Code, so that the Portfolio will be relieved
of  federal income tax on that part of its net investment income and net capital
gain that is distributed to shareholders.
 
   
    Each Portfolio intends to  distribute substantially all  of its taxable  net
investment  income (including, for this purpose, net short-term capital gain) to
shareholders. Dividends from a Portfolio's net investment income are taxable  to
shareholders  as  ordinary income,  whether received  in  cash or  in additional
shares. Such dividends paid  by a Portfolio generally  will qualify for the  70%
dividends-received  deduction  for corporate  shareholders. Each  Portfolio will
report annually to its shareholders the amount of dividend income qualifying for
such treatment.
    
 
    Distributions of net capital gain (the excess of net long-term capital  gain
over  net  short-term capital  loss) are  taxable  to shareholders  as long-term
capital gain, regardless of how long  shareholders have held their shares.  Each
Portfolio  will send reports annually to  shareholders of the federal income tax
status of all distributions made during the preceding year.
 
    Each  Portfolio  intends   to  make  sufficient   distributions  or   deemed
distributions  of its ordinary income and capital gain net income (the excess of
short-term and  long-term capital  gain over  short-term and  long-term  capital
losses, including any available capital loss carryforwards), prior to the end of
each calendar year to avoid liability for federal excise tax.
 
    Dividends  and  other  distributions  declared by  a  Portfolio  in October,
November or December of any year and payable to shareholders of record on a date
in such month will be deemed to have been paid by the Portfolio and received  by
the  shareholders on December 31  of that year if  the distributions are paid by
the Portfolio at any time during the following January.
 
                                       37
<PAGE>
   
    The Fund may be required to withhold  and remit to the U.S. Treasury 31%  of
any  dividends, capital gains distributions and  redemption proceeds paid to any
individual or  certain other  non-corporate shareholder  (1) who  has failed  to
provide  a  correct taxpayer  identification  number (generally  an individual's
social security number  or non-individual's employer  identification number)  on
the  Application Form, (2) who is subject  to backup withholding by the Internal
Revenue Service, or (3) who has not certified to the Fund that such  shareholder
is  not  subject  to  backup  withholding. This  backup  withholding  is  not an
additional  tax,  and  any  amounts   withheld  may  be  credited  against   the
shareholder's ultimate U.S. tax liability.
    
 
    The  sale, exchange or redemption  of shares will result  in taxable gain or
loss to the selling, exchanging or redeeming shareholder, depending upon whether
the fair market value of the sale, exchange or redemption proceeds exceed or are
less than the shareholder's  adjusted basis in the  sold, exchanged or  redeemed
shares. If capital gain distributions have been made with respect to shares that
are  sold at a loss  after being held for  six months or less,  then the loss is
treated as  a  long-term  capital  loss  to  the  extent  of  the  capital  gain
distributions.
 
    Conversion  of  shares  between  classes  are  not  taxable  events  to  the
shareholder.
 
    Shareholders are urged  to consult  with their tax  advisors concerning  the
application of state and local income taxes to investments in a Portfolio, which
may differ from the federal income tax consequences described above.
 
    Investment  income  received  by  a Portfolio  from  sources  within foreign
countries may be subject to foreign income taxes withheld at the source. To  the
extent  that a Portfolio  is liable for  foreign income taxes  so withheld, each
Portfolio intends to operate so as to meet the requirements of the Code to  pass
through  to the shareholders credit for foreign income taxes paid. Although each
Portfolio intends to  meet Code  requirements to  pass through  credit for  such
taxes, there can be no assurance that each Portfolio will be able to do so.
 
    THE TAX DISCUSSION SET FORTH ABOVE IS INCLUDED FOR GENERAL INFORMATION ONLY.
PROSPECTIVE  INVESTORS SHOULD CONSULT THEIR OWN TAX ADVISERS WITH RESPECT TO THE
TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN THE PORTFOLIO.
 
                             PORTFOLIO TRANSACTIONS
 
    The Adviser selects the brokers or  dealers that will execute the  purchases
and  sales  of investment  securities  for each  of  the Fund's  portfolios. The
Adviser seeks the best execution of all portfolio transactions. A portfolio  may
pay  higher commission rates than the lowest available when the Adviser believes
it is reasonable to do  so in light of the  value of the research,  statistical,
and pricing services provided by the broker effecting the transaction.
 
    It is not the Fund's practice to allocate brokerage or principal business on
the  basis of sales of shares which  may be made through intermediary brokers or
dealers. However, the Adviser may,  consistent with NASD rules, place  portfolio
orders  with qualified broker-dealers who  recommend the applicable portfolio to
their clients or who act  as agents in the purchase  of shares of the  portfolio
for their clients.
 
    Subject  to  the overriding  objective of  obtaining  the best  execution of
orders, the  Fund may  use broker-dealer  affiliates of  the Adviser,  including
Morgan  Stanley,  to effect  portfolio  brokerage transactions  under procedures
adopted by the Fund's Board of Directors. For such transactions, the  commission
rates and other
 
                                       38
<PAGE>
remuneration  paid  to  Morgan Stanley  or  other  affiliates must  be  fair and
reasonable in  comparison  to  those  of  other  broker-dealers  for  comparable
transactions  involving  similar securities  being  purchased or  sold  during a
comparable time period.
 
PORTFOLIO TURNOVER
 
   
    The Portfolios  generally do  not invest  for short-term  trading  purposes,
however,   when  circumstances  warrant,  each  Portfolio  may  sell  investment
securities without regard  to the  length of time  they have  been held.  Market
conditions  in a given year could result in a higher or lower portfolio turnover
rate than expected and the Portfolios will not consider portfolio turnover  rate
a   limiting  factor  in  making  investment  decisions  consistent  with  their
respective objectives and policies. For the fiscal year ended December 31, 1996,
the Emerging Markets Debt  Portfolio had a portfolio  turnover rate of 560%.  As
portfolio  turnover increases, the Portfolios  may expect to pay correspondingly
increased brokerage and trading costs. In addition to transaction costs,  higher
portfolio  turnover may result in the realization of capital gains. As discussed
under "Taxes," to  the extent  net short-term  capital gains  are realized,  any
distributions  resulting  from such  gains  are considered  ordinary  income for
federal income tax purposes.
    
 
                              GENERAL INFORMATION
 
DESCRIPTION OF COMMON STOCK
 
   
    The Fund  was organized  as a  Maryland corporation  on June  16, 1988.  The
Articles  of Incorporation, as amended and restated, permit the Fund to issue up
to 35 billion shares of common stock,  with $.001 par value per share.  Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number  of shares the  Fund is authorized  to issue without  the approval of the
shareholders of the Fund. The Board of Directors has the power to designate  one
or  more classes of  shares of common  stock and to  classify and reclassify any
unissued shares with respect to such classes. The shares of common stock of each
portfolio are currently classified into two classes, the Class A shares and  the
Class  B  shares,  except for  the  International  Small Cap,  Money  Market and
Municipal Money Market Portfolios which offer only Class A shares.
    
 
    The  shares  of   the  Portfolios,   when  issued,  will   be  fully   paid,
nonassessable,  fully transferable and  redeemable at the  option of the holder.
The shares have no preference as to conversion, exchange, dividends,  retirement
or  other features and have no pre-emptive  rights. The shares of each Portfolio
have non-cumulative rights, which means that the holders of more than 50% of the
shares voting for the election of Directors  can elect 100% of the Directors  if
they  choose  to do  so.  Persons or  organizations owning  25%  or more  of the
outstanding shares of a Portfolio may be presumed to "control" (as that term  is
defined  in the 1940  Act) that Portfolio.  Under Maryland law,  the Fund is not
required to hold an annual meeting of its shareholders unless required to do  so
under the 1940 Act.
 
REPORTS TO SHAREHOLDERS
 
    The  Fund will send to its  shareholders annual and semi-annual reports; the
financial statements  appearing in  annual reports  are audited  by  independent
accountants.  Monthly unaudited portfolio  data is also  available from the Fund
upon request.
 
    In addition, the Adviser, or its agent, as Transfer Agent, will send to each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
 
                                       39
<PAGE>
CUSTODIAN
 
    Chase is the Fund's custodian for domestic and certain foreign assets. Chase
is not an  affiliate of  the Adviser or  the Distributor.  Morgan Stanley  Trust
Company,  Brooklyn,  New York  ("MSTC"),  an affiliate  of  the Adviser  and the
Distributor, acts as  the Fund's custodian  for assets held  outside the  United
States  and employs subcustodians approved by the Board of Directors of the Fund
in accordance with regulations of the Securities and Exchange Commission for the
purpose of providing  custodial services  for such  assets. MSTC  may also  hold
certain  domestic assets for  the Fund. For more  information on the custodians,
see "General Information -- Custody Arrangements" in the Statement of Additional
Information.
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
    Chase  Global   Funds  Services   Company,   73  Tremont   Street,   Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
 
INDEPENDENT ACCOUNTANTS
 
   
    Price  Waterhouse LLP  serves as  independent accountants  for the  Fund and
audits its annual financial statements.
    
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       40
<PAGE>
   
   MORGAN STANLEY INSTITUTIONAL FUND, INC.
    
  EMERGING MARKETS AND EMERGING MARKETS DEBT PORTFOLIOS
   P.O. BOX 2798, BOSTON, MA 02208-2798
 
                           ACCOUNT REGISTRATION FORM
 
<TABLE>
<C>   <S>                                            <C>
      ACCOUNT INFORMATION                            If you need assistance in filling out this form for the Morgan Stanley
      Fill in where applicable                       Institutional Fund, please contact your Morgan Stanley representative
                                                     or call us toll free 1-(800)-548-7786. Please print all items except
                                                     signature, and mail to the Fund at the address above.
  A)  REGISTRATION
      1. INDIVIDUAL
      2. JOINT TENANTS
         (RIGHTS OF SURVIVORSHIP PRESUMED UNLESS
         TENANCY IN COMMON
         IS INDICATED)
</TABLE>
 
1.
         First Name    Initial         Last Name
2.
         First Name    Initial         Last Name
         First Name    Initial         Last Name
 
<TABLE>
<C>   <S>                                            <C>
      3. CORPORATIONS,
         TRUSTS AND OTHERS
         Please call the Fund for additional
      documents that may be required to set up
      account and to authorize transactions.
</TABLE>
 
3.
 
<TABLE>
<S>                     <C>                 <C>                   <C>               <C>
Type of Registration:   / / INCORPORATED    / /UNINCORPORATED     / / PARTNERSHIP   / /UNIFORM GIFT/TRANSFER TO MINOR
                                            ASSOCIATION                               (ONLY ONE CUSTODIAN AND MINOR PERMITTED)
</TABLE>
 
/ / TRUST ________________________  / / OTHER (Specify) ________________________
 
<TABLE>
<C>   <S>                                            <C>
  B)  MAILING ADDRESS
      Please fill in completely, including
      telephone number(s).
</TABLE>
 
/ / United States Citizen  / / Resident Alien
                   Street or P.O. Box
                   City
                   State                   Zip
Home Telephone No.                   Business Telephone No.
/ / Non-Resident Alien:
Permanent Address (Where you reside permanently for tax purposes)
                   Street Address
                   City
                   Country                   Postal Code
Home Telephone No.                    Business Telephone No.
 
Current Mailing Address (If different from Permanent Address)
                   Street Address
                   City
                   Country
Postal Code
Home Telephone No.                   Business Telephone No.
 
<TABLE>
<C>   <S>                                            <C>                                  <C>
  C)  TAXPAYER                                       Enter   your  Taxpayer   Identification  Number.   For  most  individual
      IDENTIFICATION                                 taxpayers, this is your Social Security Number.
      NUMBER
      1. INDIVIDUAL
      2.   JOINT TENANTS
           (RIGHTS OF SURVIVORSHIP PRESUMED UNLESS
           TENANCY IN COMMON
           IS INDICATED)
      For Custodian account
      of a minor (Uniform
      Gifts/Transfers to Minor
      Acts), give the Social
      Security Number of
      the minor
                                                                                          OR
                                                     1.         TAXPAYER IDENTIFICATION                      SOCIAL SECURITY
                                                     NUMBER ("TIN")                                NUMBER ("SSN")
                                                                                              OR
                                                     2.                                                          TIN
                                                                                                                             SSN
                                                                                              OR
                                                     TIN
                                                                                                                             SSN
                                                     IMPORTANT TAX INFORMATION
                                                     You  (as a payee) are required by law to provide us (as payer) with your
                                                     correct TIN(s)  or SSN(s).  Accounts that  have a  missing or  incorrect
                                                     TIN(s)  or SSN(s) will be subject to backup withholding at a 31% rate on
                                                     dividends, distributions and other payments. If you have not provided us
                                                     with your correct TIN(s) or SSN(s), you may be subject to a $50  penalty
                                                     imposed by the Internal Revenue Service.
                                                     Backup  withholding  is  not an  additional  tax; the  tax  liability of
                                                     persons subject to backup withholding will  be reduced by the amount  of
                                                     tax  withheld.  If withholding  results in  an  overpayment of  taxes, a
                                                     refund may be obtained.
                                                     You may be  notified that you  are subject to  backup withholding  under
                                                     Section  3406(a)(1)(C)  of the  Internal Revenue  Code because  you have
                                                     underreported interest or dividends or you were required to, but  failed
                                                     to,  file a  return which would  have included a  reportable interest or
                                                     dividend payment.
</TABLE>
 
<PAGE>
 
   
<TABLE>
<C>   <S>                                  <C>                             <C>                   <C>
  D)  PORTFOLIO AND                        For Purchase of the following   / / Class A Shares $  / / Class B Shares $
      CLASS SECTION                        Portfolio(s):                   / / Class A Shares $  / / Class B Shares $
      (Class A shares minimum $500,000     Emerging Markets Portfolio
      for each Portfolio and Class B       Emergi9ng markets Debt
      shares minimum $100,000 for each     Portfolio
      Portfolio. Please indicate
      Portfolio, class and amount.
                                                                           Total Initial Investment $
</TABLE>
    
 
<TABLE>
<C>   <S>                        <C>
  E)  METHOD OF
      INVESTMENT
      Please indicate
      portfolio, manner of
      payment.
</TABLE>
 
Payment by:
 
/ / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND,
INC.--PORTFOLIO NAME)
 
<TABLE>
<S>                                                                          <C>
/ / Exchange $ From                                                                     -- - - - - - - - - - -- - -
                            Name of Portfolio                                                   Account No.
/ / Account previously established by:  / / Phone exchange  / / Wire on                 -- - - - - - - - - - -- - -
                                                                                      Account No.               (Check
                                                                                (Previously assigned by the Fund)     Digit)
                                                                                                                          Date
</TABLE>
 
<TABLE>
<C>   <S>                        <C>
  F)  DISTRIBUTION               Income dividends and capital gains distributions (if any) to
      OPTION                     be reinvested in additional shares unless either box below
                                 is checked.
                                 / / Income dividends to be paid in cash, capital gains
                                 distributions (if any) in shares.
                                 / / Income dividends and capital gains distributions (if
                                 any) to be paid in cash.
</TABLE>
 
<TABLE>
<C>   <S>                             <C>                                       <C>
  G)  TELEPHONE                       / / I/we hereby authorize the Fund and
      REDEMPTION                      its agents to honor any telephone         Name of COMMERCIAL Bank (Not Savings
      AND EXCHANGE                    requests to wire redemption proceeds to   Bank)
      OPTION                          the commercial bank indicated at right    Bank Account No.
      Please select at time of        and/or mail redemption proceeds to the
      initial application if you      name and address in which my/our fund
      wish to redeem or exchange      account is registered if such requests                                        Bank
      shares by telephone. A          are believed to be authentic.                                                  ABA
      SIGNATURE GUARANTEE IS          The Fund and the Fund's Transfer Agent                                         No.
      REQUIRED IF BANK ACCOUNT IS     will employ reasonable procedures to
      NOT REGISTERED IDENTICALLY TO   confirm that instructions communicated    Name(s) in which your BANK Account is
      YOUR FUND ACCOUNT.              by telephone are genuine. These           Established
      TELEPHONE REQUESTS FOR          procedures include requiring the
      REDEMPTIONS OR EXCHANGE WILL    investor to provide certain personal      Bank's Street
      NOT BE HONORED UNLESS THE BOX   identification information at the time    Address
      IS CHECKED.                     an account is opened and prior to
                                      effecting each transaction requested by   City  State  Zip
                                      telephone. In addition, all telephone
                                      transaction requests will be recorded
                                      and investors may be required to provide
                                      additional telecopied written
                                      instructions of transaction requests.
                                      Neither the Fund nor the Transfer Agent
                                      will be responsible for any loss,
                                      liability, cost or expense for following
                                      instructions received by telephone that
                                      it reasonably believes to be genuine.
</TABLE>
 
<TABLE>
<C>   <S>                                  <C>
  H)  INTERESTED PARTY
      OPTION                                                                                                Name
      In addition to the account
      statement sent to my/our registered
      address, I/we hereby authorize the                                                                   Address
      fund to mail duplicate statements
      to the name and address provided at  City         State         Zip Code
      right.
</TABLE>
 
<TABLE>
<C>   <S>                                  <C>
  I)  DEALER
      INFORMATION
                                           Representative Name              Representative No.             Branch
                                           No.
</TABLE>
 
<TABLE>
<C>   <S>                                  <C>
  J)  SIGNATURE OF
      ALL HOLDERS
      AND TAXPAYER
      CERTIFICATION
      Sign Here ,
</TABLE>
 
<TABLE>
<S>                                  <C>
The undersigned certify that I/we have full authority and legal capacity
to purchase and redeem shares of the Fund and affirm that I/we have
received a current Prospectus of the Morgan Stanley Institutional Fund,
Inc. and agree to be bound by its terms.
  BY SIGNING THIS  APPLICATION, I/WE HEREBY  CERTIFY UNDER PENALTIES  OF
PERJURY THAT THE INFORMATION ON THIS APPLICATION IS COMPLETE AND CORRECT
AND  THAT  AS REQUIRED  BY FEDERAL  LAW  (PLEASE CHECK  APPLICABLE BOXES
BELOW):
 
/ / U.S. CITIZEN(S)/TAXPAYER(S):
 
      / / I/WE CERTIFY THAT (1)  THE NUMBER(S) SHOWN ABOVE ON THIS  FORM
          IS/ARE  THE  CORRECT SSN(S)  OR TIN(S)  AND  (2) I/WE  ARE NOT
          SUBJECT TO ANY BACKUP WITHHOLDING EITHER BECAUSE (A) I/WE  ARE
          EXEMPT  FROM  BACKUP  WITHHOLDING;  (B)  I/WE  HAVE  NOT  BEEN
          NOTIFIED BY THE INTERNAL REVENUE SERVICE ("IRS") THAT I/WE ARE
          SUBJECT TO  BACKUP WITHHOLDING  AS A  RESULT OF  A FAILURE  TO
          REPORT  ALL INTEREST OR DIVIDENDS; OR (C) THE IRS HAS NOTIFIED
          ME/US  THAT  I   AM/WE  ARE  NO   LONGER  SUBJECT  TO   BACKUP
          WITHHOLDING.
 
      / / IF NO TIN(S) OR SSN(S) HAS/HAVE BEEN PROVIDED ABOVE, I/WE HAVE
          APPLIED, OR INTEND TO APPLY, TO THE IRS OR THE SOCIAL SECURITY
          ADMINISTRATION  FOR A TIN OR A SSN AND I/WE UNDERSTAND THAT IF
          I/ WE  DO NOT  PROVIDE  EITHER NUMBER  TO CHASE  GLOBAL  FUNDS
          SERVICES  COMPANY ("CGFSC") WITHIN 60 DAYS OF THE DATE OF THIS
          APPLICATION OR IF I/WE FAIL  TO FURNISH MY/OUR CORRECT  SSN(S)
          OR  TIN(S), I/WE MAY BE SUBJECT TO  A PENALTY AND A 31% BACKUP
          WITHHOLDING ON DISTRIBUTIONS AND REDEMPTION PROCEEDS.  (PLEASE
          PROVIDE  EITHER NUMBER ON IRS FORM  W-9). YOU MAY REQUEST SUCH
          FORM BY CALLING CGFSC AT 800-282-4404.
 
/ / NON-U.S. CITIZEN(S)/TAXPAYER(S)
  UNDER PENALTIES  OF  PERJURY, I/WE  CERTIFY  THAT I/WE  ARE  NOT  U.S.
CITIZENS  OR RESIDENTS AND I/WE ARE EXEMPT FOREIGN PERSONS AS DEFINED BY
THE INTERNAL REVENUE SERVICE.
 
THE INTERNAL  REVENUE  SERVICE DOES  NOT  REQUIRE YOUR  CONSENT  TO  ANY
PROVISION  OF THIS  DOCUMENT OTHER  THAN THE  CERTIFICATIONS REQUIRED TO
AVOID BACKUP WITHHOLDING.
 
                                     (X)
(X)                                  Signature (if joint account, both
Signature                        Date must sign)      Date
</TABLE>
<PAGE>
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
 
  NO  DEALER, SALES  REPRESENTATIVE OR ANY  OTHER PERSON HAS  BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE  CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS  HAVING BEEN AUTHORIZED BY THE FUND  OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF  THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION  TO
ANY  PERSON TO WHOM  IT IS UNLAWFUL TO  MAKE SUCH OFFER  OR SOLICITATION IN SUCH
JURISDICTION.
 
                           --------------------------
 
                               TABLE OF CONTENTS
 
   
<TABLE>
<S>                                                 <C>
                                                    PAGE
                                                    ----
Fund Expenses.....................................    2
Financial Highlights..............................    4
Prospectus Summary................................    7
Investment Objectives and Policies................   11
Additional Investment Information.................   15
Investment Limitations............................   23
Management of the Fund............................   24
Purchase of Shares................................   26
Redemption of Shares..............................   31
Shareholder Services..............................   33
Valuation of Shares...............................   34
Performance Information...........................   35
Dividends and Capital Gains Distributions.........   35
Taxes.............................................   35
Portfolio Transactions............................   37
General Information...............................   38
Account Registration Form
</TABLE>
    
 
                           EMERGING MARKETS PORTFOLIO
                        EMERGING MARKETS DEBT PORTFOLIO
 
                               PORTFOLIOS OF THE
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
 
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
 
- ---------------------------------
- ---------------------------------
- ---------------------------------
- ---------------------------------
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
     ----------------------------------------------------------------------
 
                             CHINA GROWTH PORTFOLIO
 
                               A PORTFOLIO OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
 
                P. O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
                                ----------------
    Morgan  Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management  investment  company  with  diversified  and  non-diversified  series
("portfolios").  The Fund currently consists of twenty-seven portfolios offering
a broad range  of investment choices.  The Fund is  designed to provide  clients
with  attractive alternatives for meeting their  investment needs. Shares of the
portfolios are offered with no sales charge or exchange or redemption fee  (with
the  exception of one of the portfolios). This Prospectus sets forth information
pertaining to the China Growth Portfolio (the "Portfolio").
 
    The CHINA GROWTH PORTFOLIO seeks  to provide long-term capital  appreciation
by  investing  primarily in  the equity  securities of  issuers in  The People's
Republic of China, Hong Kong and Taiwan.
 
    The Fund is designed  to meet the investment  needs of discerning  investors
who  place a premium on quality and  personal service. With Morgan Stanley Asset
Management  Inc.  as   Adviser  and   Administrator  (the   "Adviser"  and   the
"Administrator"),  and with Morgan Stanley & Co. Incorporated ("Morgan Stanley")
as Distributor, the Fund makes available to institutional investors and high net
worth individual  investors  a  series  of portfolios  which  benefit  from  the
investment expertise and commitment to excellence associated with Morgan Stanley
and its affiliates.
 
    The  Prospectus is designed to set forth concisely the information about the
Fund that a prospective investor should  know before investing and it should  be
retained  for future reference. The Fund  offers additional portfolios which are
described in  other  prospectuses.  The  Fund  currently  offers  the  following
portfolios:  (i) GLOBAL AND  INTERNATIONAL EQUITY --  Active Country Allocation,
Asian Equity, China  Growth, Emerging Markets,  European Equity, Global  Equity,
Gold,  International Equity, International Small  Cap, Japanese Equity and Latin
American Portfolios; (ii)  U.S. EQUITY  -- Aggressive  Equity, Emerging  Growth,
Equity  Growth,  Small  Cap Value  Equity,  U.S.  Real Estate  and  Value Equity
Portfolios; (iii) BALANCED -- Balanced Portfolio; (iv) FIXED INCOME --  Emerging
Markets  Debt, Fixed  Income, Global  Fixed Income,  High Yield, Mortgage-Backed
Securities, Municipal Bond and  Real Yield Portfolios; and  (v) MONEY MARKET  --
Money  Market and Municipal Money Market Portfolio. Additional information about
the Fund is contained  in a "Statement of  Additional Information" dated May  1,
1995,  which is  incorporated herein by  reference. The  Statement of Additional
Information and the Prospectuses pertaining to the other portfolios of the  Fund
are  available upon request and without charge by writing or calling the Fund at
the address and telephone number set forth above.
 
    INVESTORS SHOULD NOTE THAT THE PORTFOLIO MAY  INVEST UP TO 10% OF ITS  TOTAL
ASSETS IN RESTRICTED SECURITIES, AND UP TO 25% OF ITS TOTAL ASSETS IN RESTRICTED
SECURITIES THAT ARE RULE 144A SECURITIES. SEE "ADDITIONAL INVESTMENT INFORMATION
- --   NON-PUBLICLY   TRADED   SECURITIES,  PRIVATE   PLACEMENTS   AND  RESTRICTED
SECURITIES." INVESTMENTS  IN  RESTRICTED  SECURITIES  IN EXCESS  OF  5%  OF  THE
PORTFOLIO'S  TOTAL ASSETS MAY BE CONSIDERED  A SPECULATIVE ACTIVITY, MAY INVOLVE
GREATER RISK AND MAY INCREASE THE PORTFOLIO'S EXPENSES.
 
THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES  AND
   EXCHANGE  COMMISSION  OR ANY  STATE SECURITIES  COMMISSION, NOR  HAS THE
     SECURITIES  AND  EXCHANGE   COMMISSION  OR   ANY  STATE   SECURITIES
       COMMISSION  PASSED  UPON  THE  ACCURACY  OR  ADEQUACY  OF THIS
           PROSPECTUS.  ANY  REPRESENTATION  TO  THE  CONTRARY  IS  A
                              CRIMINAL OFFENSE.
 
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1995.
<PAGE>
                                 FUND EXPENSES
 
    The  following table illustrates all expenses and fees that a shareholder of
the China Growth Portfolio will incur:
<TABLE>
<CAPTION>
SHAREHOLDER TRANSACTION EXPENSES
- ------------------------------------------------------------
<S>                                                           <C>
Maximum Sales Load Imposed on Purchases.....................    None
Maximum Sales Load Imposed on Reinvested Dividends..........    None
Deferred Sales Load.........................................    None
Redemption Fees.............................................    None
Exchange Fees...............................................    None
 
<CAPTION>
 
ANNUAL FUND OPERATING EXPENSES
- ------------------------------------------------------------
(AS A PERCENTAGE OF AVERAGE NET ASSETS)
<S>                                                           <C>
Investment Advisory Fee (Net of Fee Waiver).................      0.90%*
Administrative & Shareholder Account Costs..................      0.15%
12b-1 Fees..................................................    None
Custody Fees................................................      0.50%
Other Expenses..............................................      0.20%
                                                              ---------
    Total Operating Expenses (Net of Fee Waiver)............      1.75%*+
                                                              ---------
                                                              ---------
<FN>
- --------------
* The Adviser has agreed to a reduction in the fees payable to it as Adviser and
  to reimburse the Portfolio, if necessary,  if such fees would cause the  total
  annual  operating expenses  of the  Portfolio to  exceed 1.75%  of its average
  daily net assets. See  "Management of the Fund  - Investment Adviser."  Absent
  this  fee waiver, the Portfolio's total  operating expenses would be estimated
  to be 2.10% of its average daily net assets. As a result of these  reductions,
  the  Investment Advisory  Fee stated above  is lower than  the contractual fee
  stated under  "Management  of  the  Fund." For  further  information  on  Fund
  expenses, see "Management of the Fund."
+ Estimated.
</TABLE>
 
    The   purpose  of  the  foregoing  table   is  to  assist  the  investor  in
understanding the various expenses that an  investor in the Portfolio will  bear
directly  or indirectly. The  expenses and fees  for the Portfolio  are based on
estimates. For purposes of calculating the estimated expenses and fees set forth
above, the table assumes that the average daily net assets of the Portfolio will
be $50,000,000. "Other Expenses" are based on estimated amounts for the  current
fiscal  year and include Board of  Directors' fees and expenses, amortization of
organizational costs, filing fees, professional  fees, and costs for reports  to
shareholders.
 
    The  following  example illustrates  the expenses  that you  would pay  on a
$1,000 investment assuming (1) a 5% annual rate of return and (2) redemption  at
the  end of each time period. As noted in the table above, the Portfolio charges
no redemption  fees  of  any kind.  The  following  example is  based  on  total
operating expenses of the Portfolio after fee waivers:
 
<TABLE>
<CAPTION>
                                                    1 YEAR  3 YEARS
                                                    ------  -------
<S>                                                 <C>     <C>
China Growth Portfolio............................  $  18   $   55
</TABLE>
 
    THIS  EXAMPLE SHOULD  NOT BE CONSIDERED  A REPRESENTATION OF  PAST OR FUTURE
EXPENSES OR  PERFORMANCE. ACTUAL  EXPENSES MAY  BE GREATER  OR LESS  THAN  THOSE
SHOWN.
 
                                       2
<PAGE>
    The  Fund intends  to comply  with all  state laws  that restrict investment
company expenses. Currently, the  most restrictive state  law requires that  the
aggregate  annual expenses  of an  investment company  shall not  exceed two and
one-half percent (2 1/2%) of  the first $30 million  of average net assets,  two
percent (2%) of the next $70 million of average net assets, and one and one-half
percent (1 1/2%) of the remaining net assets of such investment company.
 
    The  Adviser has agreed to a reduction in  the amounts payable to it, and to
reimburse the Portfolio,  if necessary, if  in any  fiscal year the  sum of  the
Portfolio's expenses exceeds the limit set by applicable state law.
 
                                       3
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
 
    The   Fund  consists  of  twenty-seven  portfolios,  offering  institutional
investors and high net  worth individual investors a  broad range of  investment
choices coupled with the advantages of a no-load mutual fund with Morgan Stanley
and  its affiliates providing customized  services as Adviser, Administrator and
Distributor. Each  portfolio  has its  own  investment objectives  and  policies
designed  to  meet its  specific goals.  This Prospectus  pertains to  the China
Growth Portfolio.
 
    -The CHINA GROWTH PORTFOLIO seeks to provide long-term capital  appreciation
     by  investing primarily in the equity securities of issuers in The People's
     Republic of China, Hong Kong and Taiwan.
 
    The other portfolios of the Fund  are described in other prospectuses  which
may  be obtained from the Fund at the  address and telephone number noted on the
cover page of  this Prospectus.  The objectives  of these  other portfolios  are
listed below:
 
    GLOBAL AND INTERNATIONAL EQUITY:
 
    -The   ACTIVE   COUNTRY   ALLOCATION  PORTFOLIO   seeks   long-term  capital
     appreciation by investing in accordance with country weightings  determined
     by  the  Adviser  in  common  stocks  of  non-U.S.  issuers  which,  in the
     aggregate, replicate broad country indices.
 
    -The  ASIAN  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation   by
     investing primarily in common stocks of Asian issuers.
 
    -The  EMERGING  MARKETS PORTFOLIO  seeks  long-term capital  appreciation by
     investing primarily in common stocks of emerging country issuers.
 
    -The EUROPEAN  EQUITY  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing primarily in common stocks of European issuers.
 
    -The  GLOBAL  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing primarily  in  common stocks  of  issuers throughout  the  world,
     including U.S. issuers.
 
    -The  GOLD  PORTFOLIO  seeks  long-term  capital  appreciation  by investing
     primarily in the equity securities of foreign and domestic issuers  engaged
     in gold-related activities.
 
    -The  INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation by
     investing primarily in common stocks of non-U.S. issuers.
 
    -The INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital  appreciation
     by  investing primarily  in common stocks  of non-U.S.  issuers with equity
     market capitalizations of less than $500 million.
 
    -The JAPANESE  EQUITY  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing primarily in the equity securities of Japanese issuers.
 
    -THE  LATIN  AMERICAN  PORTFOLIO  seeks  long-term  capital  appreciation by
     investing primarily in equity securities of Latin American issuers and debt
     securities  issued  or   guaranteed  by  Latin   American  governments   or
     governmental entities.
 
    U.S. EQUITY:
 
    -The  AGGRESSIVE EQUITY  PORTFOLIO seeks  capital appreciation  by investing
     primarily in corporate equity and equity-linked securities.
 
                                       4
<PAGE>
    -The EMERGING  GROWTH  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing   primarily   in  growth-oriented   common  stocks   of  small-to
     medium-sized corporations.
 
    -The  EQUITY  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing   in   growth-oriented  common   stocks   of  medium   and  large
     capitalization companies.
 
    -The SMALL CAP VALUE EQUITY PORTFOLIO  seeks high long-term total return  by
     investing in undervalued common stocks of small-to medium-sized companies.
 
    -The  U.S.  REAL ESTATE  PORTFOLIO seeks  to  provide above  average current
     income and long-term capital appreciation by investing primarily in  equity
     securities  of companies in  the U.S. real  estate industry, including real
     estate investment trusts.
 
    -The VALUE EQUITY PORTFOLIO seeks high  total return by investing in  common
     stocks  which the Adviser believes to  be undervalued relative to the stock
     market in general at the time of purchase.
 
    BALANCED:
 
    -The BALANCED PORTFOLIO seeks high total return while preserving capital  by
     investing  in a combination  of undervalued common  stocks and fixed income
     securities.
 
    FIXED INCOME:
 
    -The EMERGING MARKETS DEBT  PORTFOLIO seeks high  total return by  investing
     primarily   in  debt  securities   of  government,  government-related  and
     corporate issuers in emerging countries.
 
    -The FIXED INCOME PORTFOLIO seeks to produce a high total return  consistent
     with the preservation of capital by investing in a diversified portfolio of
     fixed income securities.
 
    -The  GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real rate
     of return while preserving capital by investing in fixed income  securities
     of issuers throughout the world, including U.S. issuers.
 
    -The  HIGH YIELD PORTFOLIO seeks to maximize  total return by investing in a
     diversified portfolio of high  yield fixed income  securities that offer  a
     yield  above  that  generally available  on  debt securities  in  the three
     highest rating categories of the recognized rating services.
 
    -The MORTGAGE-BACKED SECURITIES PORTFOLIO seeks  to produce as high a  level
     of  current income  as is  consistent with  the preservation  of capital by
     investing  primarily  in  a  variety  of  investment-grade  mortgage-backed
     securities.
 
    -The  MUNICIPAL  BOND PORTFOLIO  seeks to  produce a  high level  of current
     income  consistent  with  preservation  of  principal  through   investment
     primarily  in municipal obligations,  the interest on  which is exempt from
     federal income tax.
 
    -The REAL YIELD PORTFOLIO  seeks to produce a  high total return  consistent
     with  preservation of  capital by investing  in fixed  income securities of
     issuers throughout the world, including U.S. issuers.
 
    MONEY MARKET:
 
    -The MONEY MARKET PORTFOLIO  seeks to maximize  current income and  preserve
     capital  while maintaining  high levels  of liquidity  through investing in
     high quality money market instruments with remaining maturities of one year
     or less.
 
                                       5
<PAGE>
    -The MUNICIPAL MONEY MARKET PORTFOLIO  seeks to maximize current  tax-exempt
     income  and  preserve capital  while maintaining  high levels  of liquidity
     through investing in high quality  money market instruments with  remaining
     maturities of one year or less which are exempt from federal income tax.
 
INVESTMENT MANAGEMENT
 
    Morgan  Stanley Asset Management  Inc., a wholly  owned subsidiary of Morgan
Stanley Group  Inc.,  which,  together  with  its  affiliated  asset  management
companies,  at December 31, 1994 had approximately $48.7 billion in assets under
management as  an  investment  manager  or  as  a  fiduciary  adviser,  acts  as
investment  adviser to the Fund  and each of its  portfolios. See "Management of
the Fund -- Investment Adviser" and "Management of the Fund -- Administrator."
 
HOW TO INVEST
 
    Shares of the Portfolio are offered directly to investors at net asset value
with no  sales commission  or 12b-1  charges.  Share purchases  may be  made  by
sending  investments directly  to the  Fund. The  minimum initial  investment is
$500,000 for the  Portfolio. The  minimum for subsequent  investments is  $1,000
(except  for automatic reinvestment of dividends and capital gains distributions
for which there are  no minimums). The minimum  investment levels may be  waived
for  certain Morgan  Stanley employees  and customers  at the  discretion of the
Adviser. See "Purchase of Shares."
 
HOW TO REDEEM
 
    Shares of the Portfolio may  be redeemed at any  time, without cost, at  the
net  asset value per share of the Portfolio next determined after receipt of the
redemption request. The redemption price may  be more or less than the  purchase
price.  If a shareholder reduces its total investment in shares of the Portfolio
to less  than  $500,000,  the  investment may  be  subject  to  redemption.  See
"Redemption of Shares."
 
RISK FACTORS
 
    The   investment  policies  of  the   Portfolio  entail  certain  risks  and
considerations of which an investor should  be aware. The Portfolio will  invest
in  securities of  foreign issuers,  including issuers  located in  The People's
Republic of China, Hong Kong and Taiwan, which are subject to certain risks  not
typically associated with domestic securities. Governmental actions in China can
have  a significant effect  on the economic conditions  in China and surrounding
countries. Although  the  Chinese Government  has  recently begun  to  institute
economic  reform policies, there can  be no assurances that  it will continue to
pursue such  policies  or  that  such policies  will  succeed.  See  "Investment
Objectives  and Policies" and "Additional  Investment Information." In addition,
the  Portfolio  may  invest  in   repurchase  agreements,  lend  its   portfolio
securities,  purchase securities  on a when-issued  basis and  purchase and sell
options and  enter into  futures transactions  and options  thereon for  hedging
purposes.  The Portfolio may also borrow money in an amount up to 33 1/3% of its
total assets, less  liabilities and  other borrowings.  Borrowing money  creates
leverage which is a speculative activity. See "Additional Investment Information
- --  Borrowing and Other Forms of Leverage." In addition, the Portfolio may enter
in forward foreign currency exchange contracts, currency swaps, currency futures
contracts and  options  on  such  futures  contracts,  as  well  as  options  on
currencies  to hedge currency risk associated with investment in non-U.S. dollar
denominated securities. The  Portfolio may  also enter into  currency swaps  for
non-hedging  purposes.  Each of  these  investment strategies  involves specific
risks which  are  described  under  "Investment  Objectives  and  Policies"  and
"Additional  Investment Information" herein and under "Investment Objectives and
Policies" in the Statement of Additional Information.
 
                                       6
<PAGE>
                       INVESTMENT OBJECTIVE AND POLICIES
 
    The  investment objective of the Portfolio is described below, together with
the policies the  Fund employs  in its efforts  to achieve  this objective.  The
Portfolio's  investment  objective  is a  fundamental  policy which  may  not be
changed without the approval of a majority of the Portfolio's outstanding voting
securities. There is no assurance that the Fund will attain its objectives.  The
investment  policies described  below are  not fundamental  policies and  may be
changed without shareholder approval.
 
    The investment objective of the Portfolio is long-term capital appreciation.
The production  of any  current  income is  incidental  to this  objective.  The
Portfolio  seeks to achieve  its objective by investing  primarily in the equity
securities  of  China  growth  companies.  China  growth  companies  consist  of
companies  that (i) are organized  or have their principal  place of business or
principal  securities  trading  market  in   The  People's  Republic  of   China
(collectively "China"), Hong Kong or Taiwan (collectively, the "Chinese Economic
Area")  or (ii)  are engaged in  business primarily within  the Chinese Economic
Area. The  Portfolio's  Adviser may  treat  a  company as  engaged  in  business
primarily  within the Chinese Economic Area  if it reasonably believes that such
company meets the following criteria or, based on announced plans, is likely  to
meet  such criteria in the foreseeable future:  the company derives at least 50%
of its revenue from goods or services sold  or produced in, or has at least  50%
of  its assets located in, the Chinese Economic Area. The Adviser expects that a
significant portion of the Portfolio's assets invested in China growth companies
located outside of the Chinese Economic Area will be located in Asian  countries
such  as  Singapore, Malaysia,  the Philippines,  Indonesia, Korea,  Vietnam and
Thailand.
 
    Under normal circumstances, the  Portfolio will invest at  least 65% of  its
total  assets in equity securities of  China growth companies. Equity securities
are defined as: common and preferred stocks; direct equity interests in  trusts,
partnerships,  joint ventures  and other unincorporated  entities or enterprises
("direct investments");  special classes  of shares  available only  to  foreign
persons  in  markets  where  the  ownership  of  certain  classes  of  equity is
restricted to nationals or residents of  the country; American, Global or  other
types  of Depositary Receipts; investment grade debt securities convertible into
common stock  ("convertible debentures");  and common  stock purchase  warrants.
Direct  investments in China growth  companies will not exceed  25% of the total
assets of the  Portfolio. See "Risk  Factors and Special  Considerations" for  a
discussion  of the risks  associated with direct  investments. The Portfolio may
invest 25% or more of its total  assets in the securities of issuers located  in
any one country in the Chinese Economic Area.
 
    The  Portfolio may invest up to 35% of its total assets in equity securities
of companies other  than China growth  companies. The Portfolio  may also  enter
into  options on securities and indices,  options on currency, futures contracts
and options thereon,  forward foreign currency  exchange contracts and  currency
swaps. See "Additional Investment Information."
 
    The  Portfolio may invest under normal circumstances  up to 35% of its total
assets, and for temporary defensive  purposes up to all  of its assets, in  high
quality  debt  securities of  foreign and  U.S. companies  and foreign  and U.S.
governments,   their   respective    agencies,   instrumentalities,    political
subdivisions and authorities, as well as in money market instruments denominated
in  U.S. dollars or  foreign currency. See  "Additional Investment Information."
The market value of the Portfolio's  debt securities will change in response  to
interest
 
                                       7
<PAGE>
rate  changes and other  factors. During periods of  falling interest rates, the
value of  the  debt  securities  held by  the  Portfolio  generally  rises,  and
conversely,  during  periods  of  rising  interest  rates,  the  value  of  such
securities generally the  Portfolio may invest  in investment grade  convertible
debentures as indicated above, declines.
 
    As indicated above, the Portfolio may invest in investment-grade convertible
debentures.  A debt security is investment grade if  it is rated BBB or above by
Standard &  Poor's Corporation  ("S&P") or  Baa or  above by  Moody's  Investors
Service,  Inc.  ("Moody's") or  determined to  be of  comparable quality  by the
Adviser. Debt securities  rated BBB by  S&P or Baa  by Moody's have  speculative
characteristics.  Economic changes  and other  circumstances are  more likely to
lead to a weakened capacity to make principal and interest payments than is  the
case  with higher grade debt securities.  The Portfolio will promptly dispose of
any convertible debenture which is down rated or determined by the Adviser to be
below investment grade subsequent to acquisition by the Portfolio.
 
                       ADDITIONAL INVESTMENT INFORMATION
 
    REPURCHASE AGREEMENTS.  The Portfolio  may enter into repurchase  agreements
with  brokers, dealers or banks  that meet the credit  guidelines adopted by the
Fund's Board  of Directors.  In a  repurchase agreement,  the Portfolio  buys  a
security  from a seller  that has agreed  to repurchase it  at a mutually agreed
upon date and price, reflecting the interest rate effective for the term of  the
agreement.  The term of these agreements is  usually from overnight to one week,
and never  exceeds one  year. Repurchase  agreements may  be viewed  as a  fully
collateralized  loan  of money  by the  Portfolio to  the seller.  The Portfolio
always receives securities with  a market value at  least equal to the  purchase
price  (including accrued interest) as collateral,  and this value is maintained
during the term  of the  agreement. If the  seller defaults  and the  collateral
value  declines, the Portfolio might incur a loss. If bankruptcy proceedings are
commenced with  respect to  the  seller, the  Portfolio's realization  upon  the
collateral  may  be  delayed  or  limited.  The  aggregate  value  of repurchase
agreements and certain  other investments  of the  Portfolio is  limited as  set
forth under "Investment Limitations."
 
    LOANS  OF  PORTFOLIO  SECURITIES.   The  Portfolio  may  lend  securities to
brokers, dealers, domestic and foreign banks or other financial institutions for
the purpose of increasing its net investment income. These loans must be secured
continuously by cash or equivalent collateral, or by a letter of credit at least
equal to the  market value  of the securities  loaned plus  accrued interest  or
income.  There may be a risk of delay in recovery of the securities or even loss
of rights  in  the  collateral  should  the  borrower  of  the  securities  fail
financially.  The  Portfolio will  not enter  into securities  loan transactions
exceeding, in the aggregate 33  1/3%, of the market  value of its total  assets.
For   more  detailed  information  about  securities  lending,  see  "Investment
Objectives and Policies" in the Statement of Additional Information.
 
    WHEN-ISSUED AND DELAYED  DELIVERY SECURITIES.   The  Portfolio may  purchase
securities  on a  when-issued or delayed  delivery basis.  In such transactions,
instruments are bought with payment and  delivery taking place in the future  in
order  to secure what is considered to be  an advantageous yield or price at the
time of  the transaction.  The  Portfolio will  maintain  with the  Custodian  a
separate  account  with  a segregated  portfolio  of high-grade  equity  or debt
securities or cash in an amount at least equal to these commitments. The payment
obligation and the interest rates  that will be received  are each fixed at  the
time  the Portfolio enters  into the commitment  and no interest  accrues to the
Portfolio until settlement. Thus,  it is possible that  the market value at  the
time  of settlement could be  higher or lower than  the purchase price if, among
other factors, the general level
 
                                       8
<PAGE>
of interest rates has changed.  It is a current policy  of the Portfolio not  to
enter  into  when-issued commitments  exceeding, in  the  aggregate, 15%  of the
market value of  the Portfolio's total  assets less liabilities  other than  the
obligations created by these commitments.
 
    DEPOSITARY  RECEIPTS.   The Portfolio is  permitted to  invest indirectly in
securities of China growth companies  through sponsored or unsponsored  American
Depositary  Receipts  ("ADRs"), Global  Depositary  Receipts ("GDRs")  and other
types  of  Depositary  Receipts  (which,  together  with  ADRs  and  GDRs,   are
hereinafter  collectively referred to  as "Depositary Receipts"),  to the extent
such Depositary Receipts are  or become available.  Depositary Receipts are  not
necessarily  denominated in the  same currency as  the underlying securities. In
addition, the  issuers  of  the  securities  underlying  unsponsored  Depositary
Receipts  are not  obligated to disclose  material information in  the U.S. and,
therefore, there may be  less information available  regarding such issuers  and
there  may not be a correlation between such information and the market value of
the Depositary Receipts. ADRs are Depositary Receipts typically issued by a U.S.
financial institution which evidence ownership  interests in a security or  pool
of  securities issued by  a foreign issuer.  GDRs and other  types of Depositary
Receipts are typically issued by foreign banks or trust companies, although they
also may  be  issued by  U.S.  financial institutions,  and  evidence  ownership
interests  in a security or  pool of securities issued by  either a foreign or a
U.S. corporation. Generally, Depositary Receipts in registered form are designed
for use in the U.S. securities market and Depositary Receipts in bearer form are
designed for use in securities markets  outside the United States. For  purposes
of   the  Portfolio's  investment  policies,   the  Portfolio's  investments  in
Depositary  Receipts  will  be  deemed  to  be  investments  in  the  underlying
securities.
 
    FUTURES CONTRACTS AND OPTIONS ON FUTURES CONTRACTS.  The Portfolio may enter
into  futures  contracts and  options on  futures contracts  as a  hedge against
fluctuations in price of a security it holds or intends to acquire, but not  for
speculation or for achieving leverage. The Portfolio may also enter into futures
transactions  to  remain fully  invested and  to  reduce transaction  costs. The
futures contracts  may  be based  on  various securities  and  other  securities
indices,  foreign currencies  and other  financial instruments  and indices. The
Portfolio may  enter into  futures contracts  and options  on futures  contracts
provided  that not more than  5% of the Portfolio's total  assets at the time of
entering into any such contract or option  is required as deposit to secure  the
Portfolio's  obligations under all such contracts and options, in the aggregate,
and provided that  not more  than 20%  of the  Portfolio's total  assets in  the
aggregate  are invested  in options,  futures contracts  and options  on futures
contracts.
 
    The Portfolio may purchase  and write (i.e., sell)  call and put options  on
futures  contracts  that  are  traded  on  a  recognized  securities  or futures
exchange, including  non-U.S. exchanges,  to the  extent permitted  by the  U.S.
Commodity   Futures  Trading   Commission  ("CFTC"),  and   enter  into  closing
transactions with respect to such options to terminate an existing position.  An
option  on a futures contract  gives the purchaser the  right (in return for the
premium paid) to assume a position in a futures contract (a long position if the
option is a call  and a short position  if the option is  a put) at a  specified
exercise  price at any  time during the  term of the  option. The Portfolio will
purchase and write options on futures contracts for purposes identical to  those
set  forth above  for the  purchase of  a futures  contract (purchase  of a call
option or sale of a put option) and the sale of a futures contract (purchase  of
a put option or sale of a call option), or to close out a long or short position
in a futures contract.
 
    RISKS  ASSOCIATED WITH  OPTIONS AND FUTURES.   The  primary risks associated
with the use of  options, futures and  options on futures  are (i) an  imperfect
correlation  between  the change  in  market value  of  the stocks  held  by the
Portfolio or  value  of the  currencies  in  which the  Portfolio's  assets  are
invested  and the prices of futures and options relating to the stocks purchased
or sold by  the Portfolio;  and (ii)  the possible  lack of  a liquid  secondary
 
                                       9
<PAGE>
market  for a futures  contract and the  resulting inability to  close a futures
position which could have an adverse impact on the Portfolio's ability to hedge.
In the opinion of the  Board of Directors, the risk  that the Portfolio will  be
unable  to close out a futures position or options contract will be minimized by
the Portfolio's only entering into futures contracts or options transactions for
which the Adviser believes there is a liquid secondary market.
 
    OPTIONS ON  SECURITIES AND  SECURITIES  INDICES.   The Portfolio  may  write
(i.e.,  sell) covered call options and covered put options and purchase call and
put options on securities and securities  indices. The Portfolio may also  write
combinations of put and call options on the same security, known as "straddles."
Such  transactions  can generate  additional  premium income,  but  also present
increased risk.  The  Portfolio  may  also purchase  put  and  call  options  on
securities  or securities indices in anticipation of changes in the value of its
existing portfolio securities or in the prices of securities that the  Portfolio
expects to purchase at a later date. The Portfolio may purchase and sell options
that   are   traded  on   U.S.  or   foreign  exchanges   or  that   are  traded
over-the-counter.
 
    By selling  a covered  call  option, the  Portfolio would  become  obligated
during  the term of the  option to deliver the  securities underlying the option
should the  option holder  choose to  exercise the  option before  the  option's
termination  date. In  return for  the call it  has written,  the Portfolio will
receive from the purchaser (or  option holder) a premium  which is the price  of
the  option, less a commission charged by  a broker. The Portfolio will keep the
premium regardless of whether the option is exercised. By selling a covered  put
option,  the Portfolio incurs  an obligation to buy  the security underlying the
option from the purchaser of the put at the option's exercise price at any  time
during  the option period, at the  purchaser's election (certain options written
by the Portfolio will be exercisable by the purchaser only on a specific  date).
A  call option is  "covered" if the  Portfolio owns the  security underlying the
option it has  written or  has an  absolute or  immediate right  to acquire  the
security  by holding a call  option on such security,  or maintains a sufficient
amount of cash, cash equivalents or liquid securities to purchase the underlying
security. Generally, a put option is "covered" if the Portfolio maintains  cash,
U.S.  Government securities  or other high  grade debt obligations  equal to the
exercise price of the option, or if the Portfolio holds a put option on the same
underlying security with a similar or higher exercise price.
 
    When the Portfolio writes  covered call options, it  augments its income  by
the premiums received and is thereby hedged to the extent of that amount against
a  decline in the price of the underlying securities. The premiums received will
offset a  portion  of  the potential  loss  incurred  by the  Portfolio  if  the
securities  underlying the  options are  ultimately sold  by the  Portfolio at a
loss. However, during the  option period, the Portfolio  has, in return for  the
premium  on the option, given up  the opportunity for capital appreciation above
the exercise price should the market price of the underlying security  increase,
but  has retained the risk  of loss should the  price of the underlying security
decline.
 
    The Portfolio  will  write put  options  to  receive the  premiums  paid  by
purchasers  (when the  Adviser wishes  to purchase  the security  underlying the
option at  a price  lower  than its  current market  price,  in which  case  the
Portfolio  will write the covered put at  an exercise price reflecting the lower
purchase price sought) and to close out a long put option position.
 
    The Portfolio  may  also purchase  put  or  call options  on  its  portfolio
securities and securities indices. When the Portfolio purchases a call option it
acquires  the right  to buy  a designated  security at  a designated  price (the
"exercise price"), and when the Portfolio purchases a put option it acquires the
right to sell a designated  security at the exercise price,  in each case on  or
before  a  specified  date  (the  "termination  date"),  which  is  usually  not
 
                                       10
<PAGE>
more than nine  months from the  date the  option is issued.  The Portfolio  may
purchase call options to close out a covered call position or to protect against
an  increase in the price of a security it anticipates purchasing. The Portfolio
may purchase put options on securities which  it holds in its portfolio only  to
protect  itself against a decline in the value  of the security. If the value of
the underlying  security  were to  fall  below the  exercise  price of  the  put
purchased  in  an amount  greater  than the  premium  paid for  the  option, the
Portfolio would incur no  additional loss. The Portfolio  may also purchase  put
options  to close out written  put positions in a  manner similar to call option
closing  purchase  transactions.  The  Portfolio  may  not  enter  into  options
transactions if more than 20% of the Portfolio's total assets, in the aggregate,
are invested in options, futures contracts and options on futures contracts.
 
    OPTIONS  ON CURRENCIES.   The Portfolio may purchase  and write (i.e., sell)
put and  call options  on  foreign currencies  for  the purposes  of  protecting
against  declines in the  U.S. dollar value of  foreign portfolio securities and
anticipated dividends  on such  securities  and against  increases in  the  U.S.
dollar  cost of foreign securities to be acquired. The Portfolio may use options
on currency to cross-hedge, which involves writing or purchasing options of  one
currency to hedge against changes in exchange rates for a different currency, if
there  is a  pattern of  correlation between the  two currencies.  As with other
kinds of options  transactions, however,  the writing  of an  option on  foreign
currency  will constitute only a partial hedge,  up to the amount of the premium
received. The Portfolio could be required to purchase or sell foreign currencies
at disadvantageous exchange rates, thereby incurring losses. The purchase of  an
option  on foreign currency  may constitute an  effective hedge against exchange
rate fluctuations; however, in the event  of exchange rate movements adverse  to
the  Portfolio's position,  the Portfolio may  forfeit the entire  amount of the
premium plus related transaction costs. In addition, the Portfolio may  purchase
call  or  put options  on  currency for  non-hedging  purposes when  the Adviser
anticipates that the currency  will appreciate or depreciate  in value, but  the
securities  denominated in  that currency  do not  present attractive investment
opportunities. The Portfolio  may not  enter into options  transactions if  more
than  20%  of the  Portfolio's total  assets  in the  aggregate are  invested in
options, futures contracts and options on futures contracts.
 
    FORWARD FOREIGN CURRENCY EXCHANGE CONTRACTS.   The Portfolio may enter  into
forward  foreign currency exchange contracts ("forward contracts") which provide
for the purchase or sale of an amount of a specified currency at a future  date.
Purposes  for  which  such  contracts may  be  used  include  protecting against
fluctuations in the value of a foreign currency against the U.S. dollar  between
the  trade  date  and settlement  date  when  the Portfolio  purchases  or sells
securities, locking in the U.S. dollar value of dividends declared on securities
held by  the  Portfolio  and  generally protecting  the  U.S.  dollar  value  of
securities  held  by  the  Portfolio  against  exchange  rate  fluctuation. Such
contracts may  also be  used as  a  protective measure  against the  effects  of
fluctuating  rates of currency exchange  and exchange control regulations. While
such forward contracts may limit losses to the Portfolio as a result of exchange
rate fluctuation, they will  also limit any gains  that may otherwise have  been
realized.  See "Investment Objectives and  Policies -- Forward Currency Exchange
Contracts" in the Statement of Additional Information.
 
    CURRENCY SWAPS.   The  Portfolio  may enter  into  currency swaps  for  both
hedging  and non-hedging purposes. Currency swaps involve the exchange of rights
to make  or receive  payments in  specified currencies.  Currency swaps  usually
involve the delivery of the entire principal value of one designated currency in
exchange  for  the other  designated currency.  Therefore, the  entire principal
value of a currency swap is subject to the risk that the other party to the swap
will default on its contractual delivery obligations. The use of currency  swaps
is a
 
                                       11
<PAGE>
highly  specialized  activity  which involves  investment  techniques  and risks
different from those associated with ordinary portfolio securities transactions.
Because currency swaps  are individually  negotiated, the  Portfolio expects  to
achieve  an acceptable degree  of correlation between  its portfolio investments
and its currency swap positions. If the Adviser is incorrect in its forecasts of
market values and  currency exchange  rates, the investment  performance of  the
Portfolio would be less favorable than it would have been if currency swaps were
not used.
 
    FOREIGN  CURRENCY CONSIDERATIONS.   The Portfolio's assets  will be invested
principally in securities of China growth companies and substantially all of the
income received by the Portfolio will be in foreign currencies including Chinese
renminbi and  Hong  Kong  dollars.  However,  the  Portfolio  will  compute  and
distribute  its income in  U.S. dollars, and  the computation of  income will be
made on the  date that  the income  is earned by  the Portfolio  at the  foreign
exchange  rate in effect on  that date. Therefore, if  the value of the relevant
foreign currency falls relative  to the U.S. dollar  between the earning of  the
income and the time at which the Portfolio converts the foreign currency to U.S.
dollars,  the Portfolio will be required to borrow money or liquidate securities
in order to make  distributions if the Portfolio  has insufficient cash in  U.S.
dollars  to meet distribution  requirements. The liquidation  of investments, if
required, may  have  an  adverse  impact  on  the  Portfolio's  performance.  In
addition,  changes in the exchange rates at which such foreign currencies may be
converted into U.S. dollars will affect the dollar value of securities owned  by
the  Portfolio and the  unrealized appreciation or  depreciation of investments.
The Portfolio will conduct its foreign currency exchange transactions either  on
a  cash  basis at  the cash  rate  prevailing in  the foreign  currency exchange
market, or  through  entering into  forward,  futures or  options  contracts  to
purchase or sell foreign currencies.
 
    The  Portfolio may seek to  protect the value of some  portion or all of its
portfolio holdings against currency risks  by engaging in hedging  transactions.
Currently, there is no market in which the Portfolio may engage in many of these
hedging  transactions, including with respect to  the renminbi, and there can be
no guarantee  that  instruments  suitable  for hedging  currency  or  market  or
interest  rate shifts will be available at the time when the Portfolio wishes to
use them. The Portfolio  is authorized to enter  into forward currency  exchange
contracts  and currency futures contracts and options on such futures contracts,
as well as to enter into currency swaps  and to purchase put or call options  on
foreign currencies, in U.S. or foreign markets, to the extent available.
 
    DIRECT  INVESTMENTS.  The Portfolio may invest up to 25% of its total assets
in direct investments in China growth companies. Direct investments include  (i)
the  private  purchase  from  trusts,  partnerships,  joint  ventures  and other
unincorporated entities or enterprises of  an equity interest in the  enterprise
in  the form of shares  of common stock or other  equity interests; and (ii) the
purchase of such an equity interest  in an enterprise from a principal  investor
in  the enterprise. Certain of  the Portfolio's direct investments, particularly
in China, may include investments in smaller, less seasoned companies, or  which
may  be dependent on a limited management  group. In some cases, the Portfolio's
direct investments will fund  new operations for an  enterprise which itself  is
engaged  in similar  operations or  is affiliated  with an  organization that is
engaged in similar operations. Such direct  investments may be made in  entities
that  are reasonably expected  in the foreseeable future  to become China growth
companies, either by  expanding current operations  or establishing  significant
operations in the Chinese Economic Area.
 
    RISKS  ASSOCIATED WITH DIRECT INVESTMENTS.  Direct investments may involve a
higher degree of  business and  financial risk  that can  result in  substantial
losses.  Because  of  the  absence  of  any  public  trading  market  for  these
investments, the Portfolio  may take  longer to liquidate  these positions  than
would  be the case for publicly traded securities. Although these securities may
be   resold   in    privately   negotiated   transactions,    the   prices    on
 
                                       12
<PAGE>
these  sales could be less than those  originally paid by the Portfolio, or less
than what  may  be  considered  their fair  value.  Furthermore,  issuers  whose
securities  are not publicly traded may not  be subject to public disclosure and
other investor protection requirements applicable to publicly traded securities.
If such securities are  required to be registered  under the securities laws  of
one  or more jurisdictions before being resold, the Portfolio may be required to
bear the expenses of registration. In addition, in the event the Portfolio sells
unlisted securities,  any capital  gains realized  on such  transactions may  be
subject  to higher rates  of taxation than  taxes payable on  the sale of listed
securities.
 
    NON-PUBLICLY  TRADED   SECURITIES,   PRIVATE   PLACEMENTS   AND   RESTRICTED
SECURITIES.  The Portfolio may invest in securities that are neither listed on a
stock   exchange  nor  traded  over-the-counter,  including  direct  investments
(discussed above). Investing in  such unlisted equity  securities may involve  a
high  degree  of business  and  financial risk  that  can result  in substantial
losses. As  a  result of  the  absence of  a  public trading  market  for  these
securities,  they may be  less liquid than  publicly traded securities. Although
these securities may be resold in privately negotiated transactions, the  prices
realized  from  these sales  could be  less  than those  originally paid  by the
Portfolio or less than what may be considered the fair value of such securities.
Further, companies whose securities are not  publicly traded may not be  subject
to  the disclosure  and other  investor protection  requirements which  might be
applicable if  their securities  were publicly  traded. If  such securities  are
required to be registered under the securities laws of one or more jurisdictions
before  being resold,  the Portfolio  may be  required to  bear the  expenses of
registration. As a general matter, the Portfolio may not invest more than 15% of
its total assets in illiquid securities, including securities for which there is
no readily available secondary market nor more  than 10% of its total assets  in
securities  that are  restricted from  sale to  the public  without registration
("Restricted Securities") under  the Securities  Act of 1933  (the "1933  Act").
Nevertheless,  subject  to  the  foregoing  limit  on  illiquid  securities, the
Portfolio may invest up to 25% of its total assets in Restricted Securities that
can be offered and sold to qualified institutional buyers under Rule 144A  under
that  Act ("144A Securities"). The Board of Directors has adopted guidelines and
delegated to the Adviser, subject to the supervision of the Board of  Directors,
the  daily function  of determining  and monitoring  the liquidity  of Rule 144A
securities. Rule 144A securities may become illiquid if qualified  institutional
buyers are not interested in acquiring the securities.
 
    FOREIGN  INVESTMENT RISK FACTORS.  Investors should recognize that investing
in China growth companies and other  foreign issuers involves certain risks  and
special considerations, including those set forth below, which are not typically
associated with investing in securities of U.S. issuers. Investing in securities
issued by foreign companies and governments involves considerations and possible
risks  not typically associated with investing  in securities issued by the U.S.
Government and U.S. corporations. The values of foreign investments are affected
by  changes  in  currency  exchange  rates  or  exchange  control   regulations,
application  of  foreign  tax  laws,  including  withholding  taxes,  changes in
governmental administration  or economic  or  monetary policy  (in the  U.S.  or
abroad)  or changed circumstances in dealings  between nations and the Portfolio
may incur costs in  connection with conversions  between various currencies.  In
addition,  foreign brokerage commissions are generally  higher than in the U.S.,
and foreign securities markets may be less liquid, more volatile and subject  to
less  governmental supervision than  in the U.S.  Investments in foreign issuers
could  be  affected  by  other  factors  not  present  in  the  U.S.,  including
expropriation,  confiscatory taxation,  lack of uniform  accounting and auditing
standards and  potential  difficulties  in  enforcing  contractual  obligations.
Transactions in the securities of foreign issuers could be subject to settlement
delays.
 
                                       13
<PAGE>
    Because  the Portfolio normally invests at least  65% of its total assets in
equity securities of China growth companies, its investment performance will  be
especially affected by events affecting the Chinese Economic Area. The value and
liquidity  of  such  investments may  be  affected favorably  or  unfavorably by
political, economic, fiscal,  regulatory or  other developments  in the  Chinese
Economic  Area  or  neighboring  regions. The  extent  of  economic development,
political stability  and market  depth  of different  countries in  the  Chinese
Economic  Area varies widely. Certain countries in the Chinese Economic Area are
either comparatively underdeveloped or are in the process of becoming developed.
Investments in China  growth companies typically  involve greater potential  for
gain  or loss than investments in  securities of issuers in developed countries.
In comparison to the  U.S. and other  developed countries, developing  countries
may  have  relatively unstable  governments and  economies based  on only  a few
industries. In light of the  Portfolio's investment objective and policies,  the
Portfolio will likely be particularly sensitive to changes in China's economy as
the result of a reversal of economic liberalization, political unrest or changes
in China's trading status.
 
    MARKET CHARACTERISTICS.  The securities markets in the Chinese Economic Area
and  the  surrounding region  are substantially  smaller,  less liquid  and more
volatile than  the  major  securities  markets in  the  United  States.  A  high
proportion  of the  shares of many  issuers may be  held by a  limited number of
persons and  financial  institutions,  which  may limit  the  number  of  shares
available  for investment by  the Portfolio. Similarly,  volume and liquidity in
the equity markets  in the Chinese  Economic Area  are less than  in the  United
States and, at times, price volatility can be greater than in the United States.
A  limited number of issuers  in the securities markets  of the Chinese Economic
Area  may   represent   a   disproportionately  large   percentage   of   market
capitalization and trading value. The limited liquidity of securities markets in
the  Chinese Economic Area may also affect the Portfolio's ability to acquire or
dispose of securities at  the price and  time it wishes to  do so. In  addition,
restrictions  on foreign  investment in  equity securities  listed on securities
exchanges in the  Chinese Economic Area  may impair the  Portfolio's ability  to
diversify  its  investments among  certain  industry sectors  and  may adversely
influence the prices paid by the Portfolio for such securities.
 
    The Chinese Economic Area  stock markets are undergoing  a period of  growth
and  change  which may  result  in trading  volatility  and difficulties  in the
settlement and recording of transactions,  and in interpreting and applying  the
relevant law and regulations. In particular, the securities industry in China is
not  well developed. China  has no securities  laws of nationwide applicability.
The prices at  which the Portfolio  may acquire investments  may be affected  by
trading  by  persons  with  material non-public  information  and  by securities
transactions by  brokers in  anticipation of  transactions by  the Portfolio  in
particular securities.
 
    POLITICAL,  ECONOMIC  AND  OTHER  FACTORS.   The  Portfolio  will  invest in
countries with emerging economies or securities markets. Political and  economic
structures in many of such countries may be undergoing significant evolution and
rapid  development,  and  such  countries may  lack  the  social,  political and
economic  stability  characteristic  of  the  United  States.  Certain  of  such
countries  have in the past failed to recognize private property rights and have
at times nationalized  or expropriated  the assets  of private  companies. As  a
result,  the risks  described above, including  the risks  of nationalization or
expropriation of assets, may be heightened. In addition, unanticipated political
or social developments may  affect the value of  the Portfolio's investments  in
those  countries and the availability to the Portfolio of additional investments
in those countries.
 
    Economies of the countries in the Chinese Economic Area may differ favorably
or unfavorably from the U.S. economy in such respect as rate of growth of  gross
national   product,   rate   of   inflation,   capital   reinvestment,  resource
self-sufficiency and balance of  payments position. As export-driven  economies,
the economies of
 
                                       14
<PAGE>
countries  in  the Chinese  Economic Area  are affected  by developments  in the
economies of their principal trading  partners. Revocation by the United  States
of  China's "Most Favored  Nation" trading status, which  the U.S. President and
Congress reconsider  annually, would  adversely affect  the trade  and  economic
development  of China and Hong Kong.  In addition, governmental actions in China
can have a  significant effect  on the  economic conditions  in the  surrounding
countries,  which  could  adversely  affect  the  value  and  liquidity  of  the
Portfolio's investments. Although the Chinese  Government has recently begun  to
institute  economic reform  policies, there  can be  no assurances  that it will
continue to pursue such policies or, if it does, that such polices will succeed.
 
                             INVESTMENT LIMITATIONS
 
    As a non-diversified investment company, the Portfolio is not limited by the
1940 Act in  the proportion  of its  total assets that  may be  invested in  the
obligations  of  a  single issuer.  Thus,  the  Portfolio may  invest  a greater
proportion of its total assets in the securities of a smaller number of  issuers
and,  as a result, will be subject to greater risk with respect to its portfolio
securities.  However,   the   Portfolio  does   intend   to  comply   with   the
diversification  requirements imposed by  the Internal Revenue  Code of 1986, as
amended, for qualification  as a regulated  investment company. See  "Investment
Limitations" in the Statement of Additional Information.
 
    The  Portfolio also operates under  certain investment restrictions that are
deemed fundamental limitations and may be changed only with the approval of  the
holders  of a  majority of the  Portfolio's outstanding  shares. See "Investment
Limitations" in  the  Statement  of Additional  Information.  In  addition,  the
Portfolio  operates  under  certain  non-fundamental  investment  limitations as
described below and in  the Statement of  Additional Information. The  Portfolio
may  not  (i) enter  into repurchase  agreements  with more  than seven  days to
maturity if, as a result, more than  15% of the market value of the  Portfolio's
total  assets  would  be  invested  in  such  repurchase  agreements  and  other
investments for which market quotations are not readily available, or which  are
otherwise  illiquid; (ii) borrow  money, except from  banks for extraordinary or
emergency purposes, and then only in amounts up to 10% of the Portfolio's  total
assets, less all liabilities and indebtedness other than the borrowing, taken at
cost at the time of borrowing; or purchase securities while borrowings exceed 5%
of  its total assets;  or mortgage, pledge  or hypothecate any  assets except in
connection with any  such borrowing in  amounts up to  10% of the  value of  the
Portfolio's  net assets  at the  time of borrowing;  (iii) invest  in fixed time
deposits with a duration of  over seven calendar days;  or (iv) invest in  fixed
time deposits with a duration of seven or less calendar days if more than 10% of
the Portfolio's total assets would be invested in these deposits.
 
                                       15
<PAGE>
                             MANAGEMENT OF THE FUND
 
    INVESTMENT ADVISER.  Morgan Stanley Asset Management Inc. (the "Adviser") is
the Investment Adviser and Administrator of the Fund and each of its portfolios.
The  Adviser  provides  investment  advice  and  portfolio  management services,
pursuant to an Investment Advisory Agreement and, subject to the supervision  of
the  Fund's Board of Directors, makes  each of the Fund's portfolio's day-to-day
investment decisions, arranges for the  execution of portfolio transactions  and
generally  manages each  of the Fund's  portfolio's investments.  The Adviser is
entitled to  receive  from the  Portfolio  an annual  investment  advisory  fee,
payable  quarterly,  equal to  1.25%  of the  average  daily net  assets  of the
Portfolio.
 
    The Adviser has agreed to a reduction  in the fees payable to it as  Adviser
and to reimburse the Portfolio, if necessary, if such fees would cause the total
annual  operating expenses of the Portfolio to exceed 1.75% of its average daily
net assets.
 
    The Adviser, with  principal offices  at 1221  Avenue of  the Americas,  New
York,  New  York  10020,  conducts a  worldwide  portfolio  management business,
providing a broad  range of portfolio  management services to  customers in  the
United  States and abroad. At December 31,  1994, the Adviser, together with its
affiliated   asset   management   companies,   managed   investments    totaling
approximately  $48.7 billion, including approximately $35.6 billion under active
management and  $13.1  billion as  Named  Fiduciary or  Fiduciary  Adviser.  See
"Management of the Fund" in the Statement of Additional Information.
 
    PORTFOLIO  MANAGERS.  EAN WAH  CHIN AND JAMES CHENG.  Ms. Chin is a Managing
Director of Morgan Stanley, and is  responsible for the Adviser's regional  Asia
ex-Japan  operations  based  in  Singapore.  She  has  shared  primary portfolio
management responsibility  for  the  Portfolio since  its  inception.  Prior  to
joining  Morgan Stanley in  1986, Ms. Chin  spent eight years  with the Monetary
Authority of Singapore and the  Government of Singapore Investment  Corporation,
where she was a portfolio manager for one of the largest portfolios in Asia. Ms.
Chin  was an ASEAN scholar educated at the University of Singapore. Mr. Cheng is
a Principal of Morgan Stanley. Mr. Cheng has shared primary portfolio management
responsibility for the Portfolio since its  inception. He joined the Adviser  in
1988  as a Portfolio Manager for Asian  markets and is currently responsible for
investments in  Hong Kong,  China, Taiwan,  and South  Korea. Prior  to  joining
Morgan  Stanley,  he  was  affiliated  with  American  Express  and  with Arthur
Andersen, where he spent three years  as an auditor/consultant. Mr. Cheng  holds
an M.B.A. from the University of Michigan, Ann Arbor.
 
    ADMINISTRATOR.    The Adviser  also  provides the  Fund  with administrative
services pursuant to  an Administration Agreement.  The services provided  under
the  Administration Agreement are subject to the supervision of the officers and
the Board of  Directors of  the Fund  and include  day-to-day administration  of
matters  related  to the  corporate existence  of the  Fund, maintenance  of its
records, preparation of reports, supervision of the Fund's arrangements with its
custodian,  and  assistance  in  the  preparation  of  the  Fund's  registration
statements  under  federal and  state  laws. The  Administration  Agreement also
provides that  the Administrator,  through  its agents,  will provide  the  Fund
dividend  disbursing and  transfer agent  services. For  its services  under the
Administration Agreement, the Fund  pays the Adviser a  monthly fee which on  an
annual basis equals 0.15% of the average daily net assets of the Portfolio.
 
    Under the U.S. Trust Administration Agreement between the Adviser and United
States  Trust  Company of  New York  ("U.S.  Trust"), U.S.  Trust has  agreed to
provide certain administrative services  to the Fund.  Pursuant to a  delegation
clause  in the  U.S. Trust  Administration Agreement,  U.S. Trust  delegates its
responsibilities to
 
                                       16
<PAGE>
Mutual Funds Service Company ("MFSC"), a subsidiary of U.S. Trust, that provides
certain administrative services to the Fund. The Adviser supervises and monitors
such administrative services provided by  MFSC. The services provided under  the
Administration  Agreement and the  U.S. Trust Administration  Agreement are also
subject to the supervision of the Board  of Directors of the Fund. The Board  of
Directors  of the  Fund has approved  the provision of  services described above
pursuant to  the  Administration Agreement  and  the U.S.  Trust  Administration
Agreement  as being in the best interest of the Fund. MFSC's business address is
73 Tremont Street, Boston, Massachusetts 02108-3913. For additional  information
regarding   the  Administration  Agreement  or  the  U.S.  Trust  Administration
Agreement,  see  "Management  of  the  Fund"  in  the  Statement  of  Additional
Information.
 
    DIRECTORS  AND OFFICERS.  Pursuant to  the Fund's Articles of Incorporation,
the Board of Directors  decides upon matters of  general policy and reviews  the
actions  of the Fund's  Adviser, Administrator and  Distributor. The officers of
the Fund conduct and supervise its daily business operations.
 
    DISTRIBUTOR.   Morgan Stanley  serves as  the exclusive  Distributor of  the
shares  of  the Fund.  Under its  Distribution Agreement  with the  Fund, Morgan
Stanley sells shares of the Portfolio upon the terms and at the current offering
price described in this Prospectus. Morgan Stanley is not obligated to sell  any
certain  number of shares of the Portfolio  and receives no compensation for its
distribution services.
 
    EXPENSES.  The Portfolio  is responsible for payment  of certain other  fees
and  expenses  (including legal  fees,  accountant's fees,  custodial  fees, and
printing and mailing  costs) specified  in the  Administration and  Distribution
Agreements.
 
                               PURCHASE OF SHARES
 
    Shares  of the Portfolio may be  purchased, without sales commission, at the
net asset value per share next  determined after receipt of the purchase  order.
See "Valuation of Shares."
 
INITIAL INVESTMENTS
 
1) BY  CHECK.   An account may  be opened  by completing and  signing an Account
   Registration Form and mailing it, together with a check ($500,000 minimum for
   the Portfolio,  with  certain exceptions  for  Morgan Stanley  employees  and
   select  customers)  payable to  "Morgan Stanley  Institutional Fund,  Inc. --
   China Growth Portfolio", to:
 
      Morgan Stanley Institutional Fund, Inc.
      P.O. Box 2798
      Boston, Massachusetts 02208-2798
 
    Payment will be  accepted only in  U.S. dollars, unless  prior approval  for
payment  by  other currencies  is  given by  the  Fund. The  portfolio(s)  to be
purchased should be designated on  the Account Registration Form. For  purchases
by check, the Fund is ordinarily credited with Federal Funds within one business
day.  Thus  your purchase  of shares  by  check is  ordinarily credited  to your
account at the net asset value per share of the Portfolio determined on the next
business day after receipt.
 
                                       17
<PAGE>
2) BY FEDERAL  FUNDS WIRE.   Purchases  may be  made by  having your  bank  wire
   Federal  Funds to the Fund's bank account.  In order to ensure prompt receipt
   of your Federal Funds Wire, it is important that you follow these steps:
 
   A.  Telephone the Fund (toll free:  1-800-548-7786) and provide us with  your
       name,  address, telephone  number, Social Security  or Tax Identification
       Number, the portfolio(s) selected, the  amount being wired, and by  which
       bank.  We will  then provide you  with a Fund  account number. (Investors
       with existing  accounts  should also  notify  the Fund  prior  to  wiring
       funds.)
 
   B.  Instruct  your  bank to  wire  the specified  amount  to the  Fund's Wire
       Concentration Bank Account (be sure to have your bank include the name of
       the portfolio(s) selected and the account number assigned to you):
 
       United States Trust Company of New York
      114 West 47th Street
      New York, NY 10036
      ABA #0210-0131-8
      DDA #20-9310-3
      Attn.: Morgan Stanley Institutional Fund, Inc.
      Ref.: (portfolio name, your account number, your account name)
      Please call before wiring funds: 1-800-548-7786
 
   C.  Complete and  sign the  Account  Registration Form  and  mail it  to  the
       address shown thereon.
 
  Federal Funds purchase orders will be accepted only on a day on which the Fund
  and  United States Trust Company  of New York (the  "Custodian Bank") are open
  for business. Your bank may charge a service fee for wiring funds.
 
3) BY BANK WIRE.   The  same procedure outlined  under "By  Federal Funds  Wire"
   above  must be  followed in  purchasing shares  by bank  wire. However, money
   transferred by bank wire may or may  not be converted into Federal Funds  the
   same  day, depending on the time the  money is received and the bank handling
   the wire. Prior to such conversion an investor's money will not be  invested.
   Your bank may charge a service fee for wiring funds.
 
ADDITIONAL INVESTMENTS
 
    You  may  add to  your account  at any  time (minimum  additional investment
$1,000, except  for  automatic  reinvestment  of  dividends  and  capital  gains
distributions for which there are no minimums) by purchasing shares at net asset
value  by mailing a check to the  Fund (payable to "Morgan Stanley Institutional
Fund, Inc. -- China Growth Portfolio") at the above address or by wiring  monies
to  the Custodian Bank as outlined above. It is very important that your account
name and the portfolio name be specified in the letter or wire to ensure  proper
crediting to your account. In order to ensure that your wire orders are invested
promptly,  you are requested  to notify one of  the Fund's representatives (toll
free: 1-800-548-7786) prior to the wire date.
 
OTHER PURCHASE INFORMATION
 
    The purchase price of  the shares of  the Portfolio is  the net asset  value
next determined after the order is received. See "Valuation of Shares." An order
received    prior   to   the    regular   close   of    the   New   York   Stock
 
                                       18
<PAGE>
Exchange ("NYSE"), which is currently 4:00 p.m. (Eastern Time), will be executed
at the  price computed  on the  date of  receipt; an  order received  after  the
regular close of the NYSE will be executed at the price computed on the next day
the NYSE is open.
 
    In  the interest  of economy  and convenience  and because  of the operating
procedures of the Fund, certificates  representing shares of the Portfolio  will
not  be issued. All shares  purchased are confirmed to  you and credited to your
account on the Fund's books  maintained by the Adviser  or its agents. You  will
have  the  same  rights  and  ownership  with  respect  to  such  shares  as  if
certificates had been issued.
 
    To ensure that checks are collected by the Fund, withdrawals of  investments
made  by check are  not presently permitted  until payment for  the purchase has
been received,  which may  take up  to eight  business days  after the  date  of
purchase.  As a  condition of this  offering, if  a purchase is  canceled due to
nonpayment or because your check does not clear, you will be responsible for any
loss the Fund or its  agents incur. If you are  already a shareholder, the  Fund
may  redeem shares from your account(s) to  reimburse the Fund or its agents for
any loss. In addition,  you may be prohibited  or restricted from making  future
investments in the Fund.
 
    Investors  may  also  invest  in  the  Fund  by  purchasing  shares  through
registered broker-dealers. Broker-dealers who make purchases for their customers
may charge a fee for such services.
 
EXCESSIVE TRADING
 
    Frequent trades involving  either substantial fund  assets or a  substantial
portion  of your account or accounts controlled by you can disrupt management of
a Portfolio and  raise its expenses.  Consequently, in the  interest of all  the
stockholders  of the Portfolio and the  Portfolio's performance, the Fund may in
its discretion bar a stockholder that engages in excessive trading of shares  of
a  Portfolio from  further purchases  of shares  of the  Fund for  an indefinite
period. The Fund considers  excessive trading to be  more than one purchase  and
sale  involving shares  of the  same Portfolio  of the  Fund within  any 120-day
period. For example,  exchanging shares of  Portfolios of the  Fund as  follows:
exchanging  shares of  Portfolio A  for shares  of Portfolio  B, then exchanging
shares of Portfolio B for shares of  Portfolio C and again exchanging shares  of
Portfolio  C  for shares  of  Portfolio B  within  a 120-day  period  amounts to
excessive trading. Two  types of  transactions are exempt  from these  excessive
trading  restrictions: (1)  trades exclusively between  money market portfolios;
and (2) trades done  in connection with an  asset allocation service managed  or
advised by MSAM and/or any of its affiliates.
 
                              REDEMPTION OF SHARES
 
    You  may  withdraw all  or  any portion  of the  amount  in your  account by
redeeming shares at any time. Please note  that purchases made by check are  not
permitted to be redeemed until payment of the purchase price has been collected,
which  may take up to  eight business days after  purchase. The Fund will redeem
shares of the Portfolio  at its next  determined net asset  value. On days  that
both  the NYSE and the Custodian Bank are open for business, the net asset value
per share of the Portfolio is determined at the regular close of trading of  the
NYSE (currently 4:00 p.m. Eastern Time). Shares of the Portfolio may be redeemed
by  mail or telephone. No charge is made for redemption. Any redemption proceeds
may be more or less than the  purchase price of your shares depending on,  among
other  factors,  the  market value  of  the  investment securities  held  by the
Portfolio.
 
                                       19
<PAGE>
BY MAIL
 
    The Portfolio will redeem  its shares at the  net asset value determined  on
the  date the  request is received  if the  request is received  in "good order"
before the regular close of the NYSE. Your request should be addressed to Morgan
Stanley  Institutional  Fund,   Inc.  P.O.  Box   2798,  Boston,   Massachusetts
02208-2798,  except that deliveries by overnight  courier should be addressed to
Morgan Stanley Institutional Fund,  Inc., c/o Mutual  Funds Service Company,  73
Tremont Street, Boston, Massachusetts 02108.
 
    "Good  order"  means that  the  request to  redeem  shares must  include the
following documentation:
 
        (a)  A letter of instruction or a stock assignment specifying the number
    of shares or dollar amount to  be redeemed, signed by all registered  owners
    of the shares in the exact names in which they are registered;
 
        (b)   Any  required   signature  guarantees   (see  "Further  Redemption
    Information" below); and
 
        (c)   Other supporting  legal documents,  if required,  in the  case  of
    estates,  trusts, guardianships,  custodianships, corporations,  pension and
    profit sharing plans and other organizations.
 
    Shareholders who are uncertain of requirements for redemption should consult
with a Morgan Stanley Institutional Fund representative.
 
BY TELEPHONE
 
    Provided you have previously elected the Telephone Redemption Option on  the
Account  Registration  Form, you  can  request a  redemption  of your  shares by
calling the Fund  and requesting  the redemption proceeds  be mailed  to you  or
wired  to your bank.  Please contact one of  Morgan Stanley Institutional Fund's
representatives for further details. In times of drastic market conditions,  the
telephone  redemption option  may be difficult  to implement.  If you experience
difficulty in making a telephone redemption, your request may be made by mail or
overnight courier and will be implemented at the net asset value next determined
after it is  received. Redemption requests  sent to the  Fund through  overnight
courier must be sent to Morgan Stanley Insitutional Fund, Inc., c/o Mutual Funds
Service  Company, 73 Tremont  Street, Boston, Massachusetts  02108. The Fund and
the  Fund's  transfer  agent  (the  "Transfer  Agent")  will  employ  reasonable
procedures  to  confirm  that  the instructions  communicated  by  telephone are
genuine. These  procedures include  requiring the  investor to  provide  certain
personal  identification information at the time  an account is opened and prior
to effecting each transaction requested by telephone. In addition, all telephone
transaction requests will be recorded and  investors may be required to  provide
additional  telecopied  written  instructions  regarding  transaction  requests.
Neither the  Fund nor  the Transfer  Agent  will be  responsible for  any  loss,
liability, cost or expense for following instructions received by telephone that
either of them reasonably believes to be genuine.
 
    To  change the commercial  bank or account  designated to receive redemption
proceeds, a written  request must  be sent  to the  Fund at  the address  above.
Requests  to change the bank  or account must be  signed by each shareholder and
each signature must be guaranteed.
 
FURTHER REDEMPTION INFORMATION
 
    Normally the  Fund will  make payment  for all  shares redeemed  within  one
business  day of receipt  of the request, but  in no event  will payment be made
more than  seven days  after receipt  of  a redemption  request in  good  order.
However,  payments to investors  redeeming shares which  were purchased by check
will not be made until  payment for the purchase  has been collected, which  may
take up to eight days after the date of purchase.
 
                                       20
<PAGE>
The  Fund may suspend  the right of  redemption or postpone  the date upon which
redemptions are  effected  at  times when  the  NYSE  is closed,  or  under  any
emergency  circumstances as determined by the Securities and Exchange Commission
(the "Commission").
 
    If the Board  of Directors determines  that it would  be detrimental to  the
best  interests of the  remaining shareholders of the  Portfolio to make payment
wholly or partly in cash, the Fund  may pay the redemption proceeds in whole  or
in part by a distribution in-kind of securities held by the Portfolio in lieu of
cash    in    conformity   with    applicable    rules   of    the   Commission.
Distributions-in-kind will be made  in readily marketable securities.  Investors
may  incur brokerage charges on the sale  of portfolio securities so received in
payment of redemptions.
 
    Due to the relatively  high cost of maintaining  smaller accounts, the  Fund
reserves  the right to  redeem shares in  any account in  the Portfolio having a
value of less than $500,000 (the net asset value of which will be promptly  paid
to the shareholder). The Fund, however, will not redeem shares based solely upon
market  reductions in net asset value. If at any time your total investment does
not equal or exceed the stated minimum  value, you may be notified of this  fact
and you will be allowed at least 60 days to make an additional investment before
the redemption is processed.
 
    To  protect  your account,  the Fund  and its  agents from  fraud, signature
guarantees are required for  certain redemptions to verify  the identity of  the
person  who has  authorized a redemption  from your account.  Please contact the
Fund for further  information. See "Redemption  of Shares" in  the Statement  of
Additional Information.
 
                              SHAREHOLDER SERVICES
 
EXCHANGE PRIVILEGE
 
    You  may exchange  shares that you  own in  the Portfolio for  shares of any
other available  portfolio of  the  Fund (except  for the  International  Equity
Portfolio).  The privilege to exchange shares  by telephone is automatic. Shares
of the Portfolio  may be  exchanged by  mail or  telephone. Before  you make  an
exchange,  you should read the Prospectus of the portfolios in which you seek to
invest. Because an exchange transaction is treated as a redemption followed by a
purchase, an  exchange would  be  considered a  taxable event  for  shareholders
subject  to  tax.  The exchange  privilege  is  only available  with  respect to
portfolios that are registered for sale in a shareholder's state of residence.
 
BY MAIL
 
    In order to  exchange shares  by mail, you  should include  in the  exchange
request the name and account number of the Portfolio, the name of the portfolios
into  which you intend to exchange shares,  and the signatures of all registered
account holders. Send the exchange request to Morgan Stanley Institutional Fund,
Inc. P.O. Box 2798, Boston, Massachusetts 02208-2798.
 
BY TELEPHONE
 
    When exchanging shares by telephone, have ready the name and account  number
of  the Portfolio, the name of the  portfolios into which you intend to exchange
shares, your  Social  Security number  or  Tax  I.D. number,  and  your  account
address.  Requests for telephone exchanges received  prior to 4:00 p.m. (Eastern
Time) are processed  at the close  of business that  same day based  on the  net
asset value of each of the portfolios at the close
 
                                       21
<PAGE>
of  business. Requests received after 4:00 p.m. (Eastern Time) are processed the
next business  day based  on the  net asset  value determined  at the  close  of
business  on such day.  For additional information  regarding responsibility for
the authenticity of  telephoned instructions,  see "Redemption of  Shares --  By
Telephone" above.
 
TRANSFER OF REGISTRATION
 
    You  may transfer  the registration  of any of  your Fund  shares to another
person by writing  to Morgan  Stanley Institutional  Fund, Inc.  P.O. Box  2798,
Boston,  Massachusetts 02208-2798.  As in the  case of  redemptions, the written
request must be received in good order before any transfer can be made.
 
                              VALUATION OF SHARES
 
    The net asset value per share of the Portfolio is determined by dividing the
total market value  of the Portfolio's  investments and other  assets, less  any
liabilities,  by the  total number of  outstanding shares of  the Portfolio. Net
asset value per share is determined as of the regular close of the NYSE on  each
day  that the NYSE is open for  business. Price information on listed securities
is taken from the  exchange where the security  is primarily traded.  Securities
listed  on a U.S. securities exchange  for which market quotations are available
are valued at  the last  quoted sale  price on the  day the  valuation is  made.
Securities  listed  on a  foreign exchange  are valued  at their  closing price.
Unlisted securities and listed securities not  traded on the valuation date  for
which market quotations are not readily available are valued at a price within a
range not exceeding the current asked price nor less than the current bid price.
The  current bid  and asked  prices are  determined based  on the  bid and asked
prices quoted on such valuation date by two reputable brokers.
 
    Bonds and other fixed income securities are valued according to the broadest
and most representative  market, which will  ordinarily be the  over-the-counter
market.  Net asset value includes interest  on fixed income securities, which is
accrued daily.  In addition,  bonds and  other fixed  income securities  may  be
valued on the basis of prices provided by a pricing service when such prices are
believed  to  reflect  the fair  market  value  of such  securities.  The prices
provided by a pricing service are determined without regard to bid or last  sale
prices,  but take into  account institutional size trading  in similar groups of
securities and any developments related  to the specific securities.  Securities
not  priced in this manner are valued at  the most recently quoted bid price, or
when securities exchange valuations are used, at the latest quoted sale price on
the day of valuation. If there is  no such reported sale, the latest quoted  bid
price will be used. Securities purchased with remaining maturities of 60 days or
less are valued at amortized cost, if it approximates market value. In the event
that  amortized  cost  does  not  approximate  market  value,  market  prices as
determined above will be used.
 
    The value of other assets and securities for which no quotations are readily
available (including  restricted  and  unlisted foreign  securities)  and  those
securities  for which it is inappropriate to determine prices in accordance with
the above stated  procedures are determined  in good faith  at fair value  using
methods  determined by the  Board of Directors. For  purposes of calculating net
asset value per share, all assets and liabilities initially expressed in foreign
currencies will be translated into U.S. dollars at the mean of the bid price and
asked price of such currencies against the U.S. dollar last quoted by any  major
bank.
 
                            PERFORMANCE INFORMATION
 
    The  Fund  may  from  time  to time  advertise  the  "total  return"  of the
Portfolio. THESE FIGURES ARE BASED ON  HISTORICAL EARNINGS AND ARE NOT  INTENDED
TO   INDICATE   FUTURE   PERFORMANCE.   The  "total   return"   shows   what  an
 
                                       22
<PAGE>
investment in the Portfolio  would have earned over  a specified period of  time
(such  as one, five or ten years), assuming that all distributions and dividends
by the Portfolio were  reinvested on the reinvestment  dates during the  period.
Total  return does not take into account  any federal or state income taxes that
may be payable on dividends and  distributions or upon redemption. The Fund  may
also include comparative performance information in advertising or marketing the
Portfolio's  shares. Such performance  information may include  data from Lipper
Analytical Services, Inc.,  other industry  publications, business  periodicals,
rating services and market indices.
 
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
 
    All  income dividends and capital  gains distributions will automatically be
reinvested in additional shares  at net asset value,  except that, upon  written
notice  to the Fund or  by checking off the  appropriate box in the Distribution
Option Section on  the Account  Registration Form,  a shareholder  may elect  to
receive  income dividends and capital gains distributions in cash. The Portfolio
expects to distribute substantially all of its net investment income in the form
of annual  dividends.  Net capital  gains,  if  any, will  also  be  distributed
annually.  Confirmations of the purchase of  shares of the Portfolio through the
automatic reinvestment of income dividends and capital gains distributions  will
be  provided, pursuant  to Rule 10b-10(b)  under the Securities  Exchange Act of
1934, as amended, on the next quarterly client statement following such purchase
of shares. Consequently, confirmations of such purchases will not be provided at
the time of completion of such purchases as might otherwise be required by  Rule
10b-10.
 
    Undistributed  net investment income is included in a portfolio's net assets
for the purpose  of calculating  net asset value  per share.  Therefore, on  the
"ex-dividend"  date, the net asset value  per share excludes the dividend (i.e.,
is reduced by  the per  share amount of  the dividend).  Dividends paid  shortly
after  the purchase  of shares by  an investor,  although in effect  a return of
capital, are taxable to shareholders subject to income tax.
 
                                     TAXES
 
    The following summary of federal income tax consequences is based on current
tax laws and  regulations, which  may be  changed by  legislative, judicial,  or
administrative action.
 
    No  attempt has been made to present  a detailed explanation of the federal,
state, or  local income  tax treatment  of the  Portfolio or  its  shareholders.
Accordingly,  shareholders  are urged  to consult  their tax  advisors regarding
specific questions as to federal, state and local income taxes.
 
    The Portfolio  is  treated as  a  separate  entity for  federal  income  tax
purposes  and is  not combined with  the Fund's other  portfolios. The Portfolio
intends to qualify for the  special tax treatment afforded regulated  investment
companies  under Subchapter M of  the Internal Revenue Code  of 1986, as amended
(the "Code"), so that the  Portfolio will be relieved  of federal income tax  on
that  part of its net investment income and net capital gain that is distributed
to shareholders.
 
                                       23
<PAGE>
    The  Portfolio distributes  substantially all  of its  net investment income
(including, for  this purpose,  net short-term  capital gain)  to  shareholders.
Dividends from the Portfolio's net investment income are taxable to shareholders
as  ordinary  income, whether  received in  cash or  in additional  shares. Such
dividends will generally  qualify for the  70% dividends-received deduction  for
corporations  only to  the extent  of the  aggregate qualifying  dividend income
received by  the Portfolio  from U.S.  corporations. The  Portfolio will  report
annually  to its shareholders the amount  of dividend income qualifying for such
treatment.
 
    Distributions of net capital gain (the excess of net long-term capital  gain
over  net  short-term capital  loss) are  taxable  to shareholders  as long-term
capital gain, regardless of  how long shareholders have  held their shares.  The
Portfolio  sends  reports annually  to shareholders  of  the federal  income tax
status of all distributions made during the preceding year.
 
    The  Portfolio   intends  to   make  sufficient   distributions  or   deemed
distributions  of its ordinary income and capital gain net income (the excess of
short-term and long-term  capital gains  over short-term  and long-term  capital
losses), including any available capital loss carryforwards, prior to the end of
each calendar year to avoid liability for federal excise tax.
 
    Dividends  and  other distributions  declared by  the Portfolio  in October,
November or December of any year and payable to shareholders of record on a date
in such month will be deemed to have been paid by the Portfolio and received  by
the  shareholders on December 31  of that year if  the distributions are paid by
the Portfolio at any time during the following January.
 
    The sale or redemption of shares may  result in taxable gain or loss to  the
redeeming  shareholder,  depending upon  whether the  fair  market value  of the
redemption proceeds exceeds or is less than the shareholder's adjusted basis  in
the  redeemed shares. If capital gain  distributions have been made with respect
to shares that are sold at a loss after being held for six months or less,  then
the  loss is treated  as a long-term capital  loss to the  extent of the capital
gain distributions.
 
    Shareholders are urged  to consult  with their tax  advisers concerning  the
application  of state  and local income  taxes to investments  in the Portfolio,
which may differ from the federal income tax consequences described above.
 
    Investment income  received by  the Portfolio  from sources  within  foreign
countries  may be subject to foreign income taxes withheld at the source. To the
extent that the Portfolio  is liable for foreign  income taxes so withheld,  the
Portfolio  intends to operate so as to meet the requirements of the Code to pass
through to the shareholders credit for  foreign income taxes paid. Although  the
Portfolio  intends to  meet Code  requirements to  pass through  credit for such
taxes, there can be no assurance that the Portfolio will be able to do so.
 
    THE  TAX  DISCUSSION  SET  FORTH  ABOVE  IS  INCLUDED  HEREIN  FOR   GENERAL
INFORMATION  ONLY. PROSPECTIVE INVESTORS  SHOULD CONSULT THEIR  OWN TAX ADVISERS
WITH RESPECT TO THE TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN THE PORTFOLIO.
 
                             PORTFOLIO TRANSACTIONS
 
    The Investment  Advisory  Agreement authorizes  the  Adviser to  select  the
brokers  or  dealers that  will execute  the purchases  and sales  of investment
securities  for  the  Portfolio  and  directs  the  Adviser  to  use  its   best
 
                                       24
<PAGE>
efforts  to obtain  the best available  price and most  favorable execution with
respect to  all transactions  for the  Portfolio. The  Fund has  authorized  the
Adviser to pay higher commissions in recognition of brokerage services which, in
the  opinion  of  the  Adviser,  are necessary  for  the  achievement  of better
execution, provided the Adviser believes this to be in the best interest of  the
Fund.
 
    Since  shares of the Portfolio are not marketed through intermediary brokers
or dealers, it  is not the  Fund's practice to  allocate brokerage or  principal
business  on the basis of sales of shares  which may be made through such firms.
However, the Adviser  may place portfolio  orders with qualified  broker-dealers
who  recommend the  Fund's portfolios or  who act  as agents in  the purchase of
shares of the Fund's portfolios their clients.
 
    In purchasing and  selling securities for  the Portfolio, it  is the  Fund's
policy to seek to obtain quality execution at the most favorable prices, through
responsible   broker-dealers.  In   selecting  broker-dealers   to  execute  the
securities transactions for the Portfolio,  consideration will be given to  such
factors  as the price of the security, the  rate of the commission, the size and
difficulty of  the  order,  the  reliability,  integrity,  financial  condition,
general  execution and operational capabilities of competing broker-dealers, and
the brokerage  and  research services  which  they  provide to  the  Fund.  Some
securities  considered for investment  by the Portfolio  may also be appropriate
for other  clients served  by the  Adviser. If  purchase or  sale of  securities
consistent  with the  investment policies  of the Portfolio  and one  or more of
these other clients served  by the Adviser  is considered at  or about the  same
time,  transactions in such securities will be allocated among the Portfolio and
such other  clients in  a manner  deemed  fair and  reasonable by  the  Adviser,
subject  to  the supervision  of  the Adviser.  Although  there is  no specified
formula for allocating such transactions, the various allocation methods used by
the Adviser, and the results of such allocations, are subject to periodic review
by the Fund's Board of Directors.
 
    Subject to the overriding objective of obtaining the best possible execution
of orders,  the Adviser  may allocate  a portion  of the  Portfolio's  brokerage
transactions  to Morgan Stanley or broker affiliates of Morgan Stanley. In order
for Morgan Stanley or  its affiliates to effect  any portfolio transactions  for
the Fund, the commissions, fees or other remuneration received by Morgan Stanley
or such affiliates must be reasonable and fair compared to the commissions, fees
or  other  remuneration  paid to  other  brokers in  connection  with comparable
transactions  involving  similar  securities  being  purchased  or  sold  on   a
securities  exchange during a comparable period  of time. Furthermore, the Board
of Directors of  the Fund, including  a majority  of the Directors  who are  not
"interested  persons,"  as defined  in the  Investment Company  Act of  1940, as
amended (the "1940 Act"), have adopted procedures which are reasonably  designed
to  provide  that any  commissions, fees  or other  remuneration paid  to Morgan
Stanley or such affiliates are consistent with the foregoing standard.
 
    Portfolio securities will not  be purchased from or  through, or sold to  or
through,  the Adviser or Morgan Stanley  or any "affiliated persons," as defined
in the 1940 Act, of Morgan Stanley when such entities are acting as  principals,
except to the extent permitted by law.
 
    Although  the  Portfolio will  not invest  for short-term  trading purposes,
investment securities may be sold from time to time without regard to the length
of time  they have  been  held. The  Portfolio  anticipates that,  under  normal
circumstances,  the  annual  portfolio  turnover  rate  may  exceed  100%.  High
portfolio turnover involves correspondingly greater transaction costs which will
be borne  directly by  the  respective Portfolio.  In addition,  high  portfolio
turnover  may  result  in more  capital  gains  which would  be  taxable  to the
shareholders of the respective Portfolio.
 
                                       25
<PAGE>
                              GENERAL INFORMATION
 
DESCRIPTION OF COMMON STOCK
 
    The Fund  was organized  as a  Maryland corporation  on June  16, 1988.  The
Articles  of Incorporation permit the Fund  to issue up to 15,000,000,000 shares
of common stock, with $.001 par value per share. Pursuant to the Fund's Articles
of Incorporation, the Board of Directors  may increase the number of shares  the
Fund  is authorized  to issue  without the approval  of the  shareholders of the
Fund. The Board of Directors has the  power to designate one or more classes  of
shares  of common stock and to classify  and reclassify any unissued shares with
respect to such classes.
 
    The  shares   of  the   Portfolio,  when   issued,  will   be  fully   paid,
non-assessable,  fully transferable and redeemable at  the option of the holder.
The shares have no preference as to conversion, exchange, dividends,  retirement
or  other features and have  no pre-emptive rights. The  shares of the Portfolio
have non-cumulative voting rights, which means that the holders of more than 50%
of the  shares voting  for  the election  of Directors  can  elect 100%  of  the
Directors  if they choose to do so.  Persons or organizations owning 25% or more
of the outstanding shares of a Portfolio  may be presumed to "control" (as  that
term is defined in the 1940 Act) that Portfolio. Under Maryland law, the Fund is
not required to hold an annual meeting of its shareholders unless required to do
so under the 1940 Act.
 
REPORTS TO SHAREHOLDERS
 
    The  Fund will send to its  shareholders annual and semi-annual reports; the
financial statements  appearing in  annual reports  are audited  by  independent
accountants.  Monthly unaudited portfolio  data is also  available from the Fund
upon request.
 
    In addition, Morgan Stanley Asset Management Inc. or its agent, as  Transfer
Agent,  will send to each shareholder having an account directly with the Fund a
monthly statement  showing transactions  in  the account,  the total  number  of
shares owned, and any dividends or distributions paid.
 
CUSTODIAN
 
    Domestic  securities and cash are held by United States Trust Company of New
York, New York, as the Fund's domestic custodian. Morgan Stanley Trust  Company,
Brooklyn, New York, acts as the Fund's custodian for foreign assets held outside
the  United States and employs  subcustodians who were approved  by the Board of
Directors of  the Fund  in accordance  with regulations  of the  Securities  and
Exchange  Commission for  the purpose of  providing custodial  services for such
assets. For  more information  on the  custodians, see  "General Information  --
Custody Arrangements" in the Statement of Additional Information.
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
    The  Mutual Funds Service Company,  73 Tremont Street, Boston, Massachusetts
02108-3913, acts as Dividend Disbursing and Transfer Agent for the Fund.
 
INDEPENDENT ACCOUNTANTS
 
   
                       serves as independent accountants for the Fund and audits
its annual financial statements.
    
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       26
<PAGE>
MORGAN STANLEY INSTITUTIONAL FUND, INC. -- CHINA GROWTH PORTFOLIO
          P.O. BOX 2798, BOSTON, MA 02208-2798
                           ACCOUNT REGISTRATION FORM
 
                             If you need assistance in filling out this form for
   ACCOUNT INFORMATION       the Morgan Stanley Institutional Fund, please
   Fill in where applicable  contact your Morgan Stanley representative or call
                             us toll free 1-(800)-548-7786. Please print all
                             items except signature, and mail to the Fund at the
                             address above.
A) REGISTRATION
   1. INDIVIDUAL
   2. JOINT TENANTS (RIGHTS OF SURVIVORSHIP PRESUMED UNLESS TENANCY IN COMMON IS
      INDICATED)
 
1.
- --------------------------------------------------------------------------------
              First Name              Initial             Last Name
2.
- --------------------------------------------------------------------------------
              First Name              Initial             Last Name
 
- --------------------------------------------------------------------------------
              First Name              Initial             Last Name
 
   3. CORPORATIONS, TRUSTS AND OTHERS Please call the Fund for additional
      documents that may be required to set up account and to authorize
      transactions.
 
3.
- --------------------------------------------------------------------------------
 
- --------------------------------------------------------------------------------
 
- --------------------------------------------------------------------------------
 
<TABLE>
<S>                     <C>               <C>                 <C>              <C>
Type of Registration:   / / INCORPORATED  / / UNINCORPORATED  / / PARTNERSHIP  / / UNIFORM GIFT/TRANSFER TO MINOR (ONLY ONE
                                              ASSOCIATION                          CUSTODIAN AND MINOR PERMITTED)
</TABLE>
 
/ / TRUST ________________________  / / OTHER (Specify) ________________________
 
B) MAILING ADDRESS
   Please fill in completely, including telephone number(s).
 
Street or P.O. Box ____________________________________________________________
City _____________________ State _____________________ Zip __________-__________
Home Telephone No. __________-__________-__________
Business Telephone No. __________-__________-__________
/ / United States Citizen  / / Resident Alien  / / Non-Resident Alien:
Indicate Country of Residence __________________________________________________
 
C) TAXPAYER IDENTIFICATION NUMBER
   If the account is in more than one name, CIRCLE THE NAME OF THE PERSON WHOSE
   TAXPAYER IDENTIFICATION NUMBER IS PROVIDED IN SECTION A) ABOVE. If no name
   is circled, the number will be considered to be that of the last name
   listed. For Custodian account of a minor (Uniform Gifts/Transfers to Minors
   Acts), give the Social Security Number of the minor.
   PART 1. Enter your Taxpayer Identification Number. For most individual
   taxpayers, this is your Social Security Number.
   TAXPAYER IDENTIFICATION NUMBER
   ------------------------------------------------------------------------
   OR
   SOCIAL SECURITY NUMBER
   ------------------------------------------------------------------------
   PART 2. BACKUP WITHHOLDING
   / / Check this box if you are NOT subject to Backup Withholding under the
   provisions of Section 3406(a)(1)(C) of the Internal Revenue Code.
   IMPORTANT TAX INFORMATION
   You  (as a  payee) are required  by law to  provide us (as  payer) with your
   correct taxpayer  identification number.  Accounts that  have a  missing  or
   incorrect   taxpayer  identification  number  will   be  subject  to  backup
   withholding at a 31% rate on dividends, distributions and other payments. If
   you have not provided us  with your correct taxpayer identification  number,
   you may be subject to a $50 penalty imposed by the Internal Revenue Service.
   Backup  withholding is not  an additional tax; the  tax liability of persons
   subject to backup withholding will be reduced by the amount of tax withheld.
   If withholding results in an overpayment of taxes, a refund may be obtained.
   You may be notified that you are subject to backup withholding under Section
   3406(a)(1)(C) of the  Internal Revenue Code  because you have  underreported
   interest  or dividends or you  were required to but  failed to file a return
   which would have included a reportable interest or dividend payment. IF  YOU
   HAVE NOT BEEN SO NOTIFIED, CHECK THE BOX IN PART 2 AT LEFT.
 
D) PORTFOLIO SELECTION
   Minimum $500,000 for the China Growth Portfolio. Please indicate amount.
   FOR PURCHASE OF $ OF CHINA GROWTH PORTFOLIO
 
E) METHOD OF INVESTMENT
   Please indicate manner of payment.
 
Payment by:
/ / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND, INC.-CHINA
    GROWTH PORTFOLIO)
 
/ / Exchange $ From                                         --
                     Name of Portfolio         Account No.
/ / Account previously established by:
/ / Phone exchange  / / Wire on                             --
                                Date
                                              Account No.          (Check Digit)
                                               (Previously assigned by the Fund)
 
<PAGE>
 
F) DISTRIBUTION OPTION
   Income dividends and capital gains distributions (if any) will be reinvested
   in additional shares unless either box below is checked.
   / / Income dividends to be paid in cash, capital gains distributions (if any)
   in shares.
   / / Income dividends and capital gains distributions (if any) to be paid in
   cash.
 
G) TELEPHONE REDEMPTION
   Please select at time of initial application if you wish to redeem shares by
   telephone. A SIGNATURE GUARANTEE IS REQUIRED IF BANK ACCOUNT IS NOT
   REGISTERED IDENTICALLY TO YOUR FUND ACCOUNT. TELEPHONE REQUESTS FOR
   REDEMPTIONS WILL NOT BE HONORED UNLESS THE BOX IS CHECKED.
 
   / / I/we hereby authorize the Fund and its agents to honor any telephone
   requests to wire redemption proceeds to the commercial bank indicated at
   right and/or mail redemption proceeds to the name and address in which
   my/our fund account is registered if such requests are believed to be
   authentic.
   THE FUND AND THE FUND'S TRANSFER AGENT WILL EMPLOY REASONABLE PROCEDURES TO
   CONFIRM THAT INSTRUCTIONS COMMUNICATED BY TELEPHONE ARE GENUINE. THESE
   PROCEDURES INCLUDE REQUIRING THE INVESTOR TO PROVIDE CERTAIN PERSONAL
   IDENTIFICATION INFORMATION AT THE TIME AN ACCOUNT IS OPENED AND PRIOR TO
   EFFECTING EACH TRANSACTION REQUESTED BY TELEPHONE. IN ADDITION, ALL
   TELEPHONE TRANSACTION REQUESTS WILL BE RECORDED AND INVESTORS MAY BE
   REQUIRED TO PROVIDE ADDITIONAL TELECOPIED WRITTEN INSTRUCTIONS OF
   TRANSACTION REQUESTS. NEITHER THE FUND NOR THE TRANSFER AGENT WILL BE
   RESPONSIBLE FOR ANY LOSS, LIABILITY, COST OR EXPENSE FOR FOLLOWING
   INSTRUCTIONS RECEIVED BY TELEPHONE THAT IT REASONABLY BELIEVES TO BE
   GENUINE.
   ----------------------------------------------------------------------------
   Name of COMMERCIAL Bank (Not Savings Bank)                Bank Account No.
   ----------------------------------------------------------------------------
   Bank ABA No.
   ----------------------------------------------------------------------------
   Name(s) in which your Bank Account is Established
   ----------------------------------------------------------------------------
   Bank's Street Address
   ----------------------------------------------------------------------------
   City                     State                     Zip
 
H) INTERESTED PARTY OPTION
   In addition to the account statement sent to my/our registered address, I/we
   hereby authorize the Fund to mail duplicate statements to the name and
   address provided at right.
   -----------------------------------------------------------------------------
   Name
- -----------------------------------------------------------------------------
- -----------------------------------------------------------------------------
   Address
   -----------------------------------------------------------------------------
   City                     State                     Zip Code
 
I) DEALER INFORMATION
   -----------------------------------------------------------------------------
   Representative Name
   -----------------------------------------------------------------------------
   Representative No.
   -----------------------------------------------------------------------------
   Branch No.
 
J) SIGNATURE OF ALL HOLDERS AND TAXPAYER CERTIFICATION
   Sign Here
 
The undersigned certify(ies) that I/we have full authority and legal capacity to
purchase  and redeem  shares of the  Fund and  affirm that I/we  have received a
current  Prospectus  of  the  China  Growth  Portfolio  of  the  Morgan  Stanley
Institutional Fund, Inc. and agree to be bound by its terms. UNDER THE PENALTIES
OF  PERJURY, I/WE CERTIFY THAT  THE INFORMATION PROVIDED IN  SECTION C) ABOVE IS
TRUE, CORRECT AND COMPLETE.
(X)                                       (X)
- ---------------------------------------   --------------------------------------
Signature          Date                   Signature          Date
<PAGE>
- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------
 
  NO  DEALER, SALES REPRESENTATIVES  OR ANY OTHER PERSON  HAS BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE  CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS  HAVING BEEN AUTHORIZED BY THE FUND  OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF  THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION  TO
ANY  PERSON TO WHOM  IT IS UNLAWFUL TO  MAKE SUCH OFFER  OR SOLICITATION IN SUCH
JURISDICTION.
 
                           --------------------------
 
                               TABLE OF CONTENTS
 
<TABLE>
<CAPTION>
                                                                            PAGE
                                                                            ----
<S>                                                                         <C>
Fund Expenses.............................................................    2
Prospectus Summary........................................................    4
Investment Objective and Policies.........................................    7
Additional Investment Information.........................................    8
Investment Limitations....................................................   15
Management of the Fund....................................................   16
Purchase of Shares........................................................   17
Redemption of Shares......................................................   19
Shareholder Services......................................................   21
Valuation of Shares.......................................................   22
Performance Information...................................................   22
Dividends and Capital Gains Distributions.................................   23
Taxes.....................................................................   23
Portfolio Transactions....................................................   24
General Information.......................................................   26
Account Registration Form
</TABLE>
 
                             CHINA GROWTH PORTFOLIO
 
                               A PORTFOLIO OF THE
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
 
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
 
- --------------------------------------------------------------------------------
- --------------------------------------------------------------------------------
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
   -------------------------------------------------------------------------
 
                            EQUITY GROWTH PORTFOLIO
                           EMERGING GROWTH PORTFOLIO
                               MICROCAP PORTFOLIO
                          AGGRESSIVE EQUITY PORTFOLIO
 
                               PORTFOLIOS OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
 
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
 
                                ----------------
 
   
    Morgan  Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company, or mutual fund, which offers redeemable shares in
a   series   of   diversified   and   non-diversified   investment    portfolios
("portfolios").  The  Fund  is  designed  to  provide  clients  with  attractive
alternatives for meeting their investment needs. The Fund currently consists  of
twenty-nine  portfolios representing a  broad range of  investment choices. This
prospectus (the "Prospectus") pertains to the Class A and the Class B shares  of
the  Equity Growth, Emerging  Growth, MicroCap and  Aggressive Equity Portfolios
(each, a "Portfolio" and collectively, the "Portfolios"). The Class A and  Class
B  shares currently offered by the  Portfolios have different minimum investment
requirements and fund  expenses. Shares of  the portfolios are  offered with  no
sales  charge, exchange  fee or redemption  fee, (except  that the International
Small Cap  Portfolio may  impose  a transaction  fee.). The  MicroCap  Portfolio
currently is not being offered.
    
 
    The  Fund is designed  to meet the investment  needs of discerning investors
who place a premium on quality  and personal service. With Morgan Stanley  Asset
Management   Inc.  as   Adviser  and   Administrator  (the   "Adviser"  and  the
"Administrator"), and with Morgan Stanley & Co. Incorporated ("Morgan  Stanley")
as Distributor, the Fund makes available to institutional investors and high net
worth  individual  investors  a  series of  portfolios  which  benefit  from the
investment expertise and commitment to excellence associated with Morgan Stanley
and its affiliates.
 
    This Prospectus is designed to set forth concisely the information about the
Fund that a prospective investor should  know before investing and it should  be
retained  for future reference. The Fund  offers additional portfolios which are
described in other prospectuses and  under "Prospectus Summary" below. The  Fund
currently  offers the following portfolios:  (i) GLOBAL AND INTERNATIONAL EQUITY
- -- Active Country Allocation, Asian  Equity, Emerging Markets, European  Equity,
Global  Equity, Gold, International  Equity, International Magnum, International
Small Cap, Japanese Equity  and Latin American Portfolios;  (ii) U.S. EQUITY  --
Aggressive  Equity,  Emerging Growth,  Equity  Growth, Small  Cap  Value Equity,
Technology, U.S. Real Estate and Value Equity Portfolios; (iii) EQUITY AND FIXED
INCOME -- Balanced Portfolio; (iv) FIXED INCOME -- Emerging Markets Debt,  Fixed
Income,  Global Fixed Income, High Yield  and Municipal Bond Portfolios; and (v)
MONEY MARKET -- Money Market  and Municipal Money Market Portfolios.  Additional
information   about  the  Fund  is  contained  in  a  "Statement  of  Additional
Information" dated May 1, 1997, which  is incorporated herein by reference.  The
Statement of Additional Information and the prospectuses pertaining to the other
portfolios  of the Fund are available upon request and without charge by writing
or calling the Fund at the address and telephone number set forth above.
 
  THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES AND
    EXCHANGE COMMISSION, NOR  HAS THE SECURITIES  AND EXCHANGE  COMMISSION
      PASSED  UPON  THE  ACCURACY  OR ADEQUACY  OF  THIS  PROSPECTUS. ANY
             REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.
 
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1997.
<PAGE>
                                 FUND EXPENSES
 
    The  following table illustrates the expenses and fees that a shareholder of
the Portfolios indicated below will incur:
 
<TABLE>
<CAPTION>
                                                           EQUITY      EMERGING                 AGGRESSIVE
                                                           GROWTH       GROWTH      MICROCAP      EQUITY
SHAREHOLDER TRANSACTION EXPENSES                          PORTFOLIO    PORTFOLIO    PORTFOLIO    PORTFOLIO
- -------------------------------------------------------  -----------  -----------  -----------  -----------
<S>                                                      <C>          <C>          <C>          <C>
Maximum Sales Load Imposed on Purchases
  Class A..............................................        None         None         None         None
  Class B..............................................        None         None         None         None
Maximum Sales Load Imposed on Reinvested Dividends
  Class A..............................................        None         None         None         None
  Class B..............................................        None         None         None         None
Deferred Sales Load
  Class A..............................................        None         None         None         None
  Class B..............................................        None         None         None         None
Redemption Fees
  Class A..............................................        None         None         None         None
  Class B..............................................        None         None         None         None
Exchange Fees
  Class A..............................................        None         None         None         None
  Class B..............................................        None         None         None         None
</TABLE>
 
   
<TABLE>
<CAPTION>
                                                           EQUITY      EMERGING                 AGGRESSIVE
                                                           GROWTH       GROWTH      MICROCAP      EQUITY
ANNUAL FUND OPERATING EXPENSES                            PORTFOLIO    PORTFOLIO    PORTFOLIO    PORTFOLIO
- -------------------------------------------------------  -----------  -----------  -----------  -----------
<S>                                                      <C>          <C>          <C>          <C>
 (AS A PERCENTAGE OF AVERAGE NET ASSETS)
Management Fee (Net of Fee Waivers)*
  Class A..............................................       0.52%        0.95%        1.05%+       0.56%
  Class B..............................................       0.52%        0.95%        1.05%+       0.56%
12b-1 Fees
  Class A..............................................        None         None         None         None
  Class B..............................................       0.25%        0.25%        0.25%        0.25%
Other Expenses
  Class A..............................................       0.28%        0.30%        0.45%+       0.44%
  Class B..............................................       0.28%        0.30%        0.45%+       0.44%
                                                         -----------  -----------  -----------  -----------
Total Operating Expenses (Net of Fee Waivers)*
  Class A..............................................       0.80%        1.25%        1.50%+       1.00%
  Class B..............................................       1.05%        1.50%        1.75%+       1.25%
                                                         -----------  -----------  -----------  -----------
                                                         -----------  -----------  -----------  -----------
</TABLE>
    
 
- ------------------------
   
*  The Adviser has  agreed to waive  its management fees  and/or reimburse  each
   Portfolio,  if necessary, if such fees would cause the total annual operating
   expenses of  the  Portfolios  to  exceed  a  specified  percentage  of  their
   respective  average daily net assets. These  reductions became or will become
   effective as  of  the inception  of  each Portfolio.  As  a result  of  these
   reductions,  the Management Fees stated above  are lower than the contractual
   fees stated under "Management of the Fund." The Adviser reserves the right to
   terminate any of its fee
    
 
                                       2
<PAGE>
   
   waivers and/or expense reimbursements at any time in its sole discretion. For
   further information on Fund expenses, see "Management of the Fund." Set forth
   below, for  each  Portfolio, are  the  management fees  and  total  operating
   expenses  absent such fee waivers and/or  expense reimbursements as a percent
   of average  daily net  assets  of the  Class A  shares  and Class  B  shares,
   respectively, of each Portfolio.
    
   
+  Estimated
    
 
   
<TABLE>
<CAPTION>
                                                                                         TOTAL OPERATING EXPENSES
                                                                                            ABSENT FEE WAIVERS
                                                               MANAGEMENT FEES ABSENT    ------------------------
PORTFOLIO                                                            FEE WAIVERS           CLASS A      CLASS B
- ------------------------------------------------------------  -------------------------  -----------  -----------
<S>                                                           <C>                        <C>          <C>
Equity Growth...............................................              0.60%               0.88%        1.12%
Emerging Growth.............................................              1.00%               1.30%        1.54%
MicroCap....................................................              1.25%               1.50%+       1.75%+
Aggressive Equity...........................................              0.80%               1.24%        1.47%
</TABLE>
    
 
- ------------------------------
   
+  Estimated.
    
 
   
    The  purpose of the table  above is to assist  the investor in understanding
the various expenses that  an investor in the  Portfolios will bear directly  or
indirectly.  Expenses  and  fees  for the  Equity  Growth,  Emerging  Growth and
Aggressive Equity Portfolios  are based on  actual figures for  the fiscal  year
ended  December 31, 1996. The  expenses and fees for  the MicroCap Portfolio are
based on estimates, assuming that the  average daily net assets of the  MicroCap
Portfolio  will be $50,000,000. Due to the continuous nature of Rule 12b-1 fees,
long term Class B shareholders may pay  more than the equivalent of the  maximum
front-end  charges otherwise permitted by the National Association of Securities
Dealers, Inc. ("NASD") Conduct Rules.
    
 
                                       3
<PAGE>
    The following  example illustrates  the expenses  that you  would pay  on  a
$1,000  investment assuming (1) a 5% annual rate of return and (2) redemption at
the end of each time period. As noted in the table above, the Portfolios  charge
no redemption fees of any kind. The example is based on total operating expenses
of the Portfolios after fee waivers.
 
   
<TABLE>
<CAPTION>
                                                                       1 YEAR       3 YEARS      5 YEARS     10 YEARS
                                                                     -----------  -----------  -----------  -----------
<S>                                                                  <C>          <C>          <C>          <C>
Equity Growth Portfolio
  Class A..........................................................   $       8    $      26    $      44    $      99
  Class B..........................................................          11           33           58          128
Emerging Growth Portfolio
  Class A..........................................................          13           40           69          151
  Class B..........................................................          15           47           82          179
MicroCap Portfolio*
  Class A..........................................................          15           47        *            *
  Class B..........................................................          18           55        *            *
Aggressive Equity Portfolio
  Class A..........................................................          10           32           55          122
  Class B..........................................................          13           40           69          151
</TABLE>
    
 
- ------------------------------
*  Because  the MicroCap Portfolio has not yet commenced operations the Fund has
   not projected expenses beyond the 3-year period shown for the Portfolio.
 
    THIS EXAMPLE SHOULD  NOT BE CONSIDERED  A REPRESENTATION OF  PAST OR  FUTURE
EXPENSES  OR  PERFORMANCE. ACTUAL  EXPENSES MAY  BE GREATER  OR LESS  THAN THOSE
SHOWN.
 
                                       4
<PAGE>
                              FINANCIAL HIGHLIGHTS
 
   
    The following table provides financial highlights for the Class A and  Class
B  shares of the Equity Growth, Emerging Growth and Aggressive Equity Portfolios
for each of  the periods  presented. The  audited financial  highlights for  the
Portfolios'  shares for  each of  the periods presented  are part  of the Fund's
financial statements which appear in the Fund's December 31, 1996 Annual  Report
to  Shareholders and which are incorporated by reference in the Fund's Statement
of Additional Information. The Portfolios' financial highlights for each of  the
periods  presented have been audited by  Price Waterhouse LLP, whose unqualified
report thereon is also incorporated by reference in the Statement of  Additional
Information.  Additional  performance  information  is  included  in  the Annual
Report. The Annual Report and the  financial statements therein, along with  the
Statement  of Additional Information, are available at  no cost from the Fund at
the address and  telephone number noted  on the cover  page of this  Prospectus.
Financial highlights are not available for the MicroCap Portfolio. After October
31,  1992, the Fund  changed its fiscal  year end to  December 31. The following
information should  be read  in conjunction  with the  financial statements  and
notes thereto.
    
 
                                       5
<PAGE>
   
                            EQUITY GROWTH PORTFOLIO
    
   
<TABLE>
<CAPTION>
                                                                                CLASS A
                                                ------------------------------------------------------------------------
                                                                YEAR ENDED                   TWO MONTHS
                                                               DECEMBER 31,                       ENDED     YEAR ENDED
                                                ------------------------------------------  DECEMBER 31,   OCTOBER 31,
                                                     1996       1995       1994       1993         1992           1992
                                                ---------  ---------  ---------  ---------  -------------  -------------
<S>                                             <C>        <C>        <C>        <C>        <C>            <C>
NET ASSET VALUE, BEGINNING OF PERIOD..........  $   14.14  $   12.02  $   12.14  $   11.88    $   11.44      $   10.66
                                                ---------  ---------  ---------  ---------  -------------  -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)...................       0.17       0.22       0.17       0.22         0.03           0.16
  Net Realized and Unrealized Gain on
   Investments................................       4.07       4.93       0.21       0.28         0.41           0.82
                                                ---------  ---------  ---------  ---------  -------------  -------------
    Total from Investment Operations..........       4.24       5.15       0.38       0.50         0.44           0.98
                                                ---------  ---------  ---------  ---------  -------------  -------------
DISTRIBUTIONS
  Net Investment Income.......................      (0.17)     (0.28)     (0.13)     (0.23)          --          (0.20)
  In Excess of Net Investment Income..........         --         --         --      (0.01)          --             --
  Net Realized Gain...........................      (3.27)     (2.75)     (0.37)        --           --             --
                                                ---------  ---------  ---------  ---------  -------------  -------------
    Total Distributions.......................      (3.44)     (3.03)     (0.50)     (0.24)          --          (0.20)
                                                ---------  ---------  ---------  ---------  -------------  -------------
NET ASSET VALUE, END OF PERIOD................  $   14.94  $   14.14  $   12.02  $   12.14    $   11.88      $   11.44
                                                ---------  ---------  ---------  ---------  -------------  -------------
                                                ---------  ---------  ---------  ---------  -------------  -------------
TOTAL RETURN..................................      30.97%     45.02%      3.26%      4.33%        3.85%          9.26%
                                                ---------  ---------  ---------  ---------  -------------  -------------
                                                ---------  ---------  ---------  ---------  -------------  -------------
RATIOS AND SUPPLEMENTAL DATA:
  Net Assets, End of Period (Thousands).......  $ 352,703  $ 158,112  $  97,259  $  73,789    $  45,985      $  36,558
  Ratio of Expenses to Average Net Assets
   (1)........................................       0.80%      0.80%      0.80%      0.80%        0.80%**        0.80%
  Ratio of Net Investment Income to Average
   Net Assets (1).............................       1.12%      1.57%      1.44%      1.59%        1.93%**        1.73%
  Portfolio Turnover Rate.....................        186%       186%       146%       172%           1%            38%
  Average Commission Rate#....................    $0.0535        N/A        N/A        N/A          N/A            N/A
- ------------------------------
(1) Effect of voluntary expense limitation
    during the period:
     Per share benefit to net investment
      income..................................      $0.01      $0.01      $0.01      $0.02        $0.01          $0.02
   Ratios before expense limitation:
     Expenses to Average Net Assets...........       0.88%      0.88%      0.89%      0.93%        1.11%**        1.01%
     Net Investment Income to Average Net
      Assets..................................       1.04%      1.49%      1.35%      1.46%        1.62%**        1.52%
 
<CAPTION>
                                                                  CLASS B
                                                               -------------
                                                PERIOD FROM    PERIOD FROM
                                                   APRIL 2,     JANUARY 2,
                                                   1991* TO     1996*** TO
                                                OCTOBER 31,    DECEMBER 31,
                                                       1991           1996
                                                -------------  -------------
<S>                                             <C>            <C>
NET ASSET VALUE, BEGINNING OF PERIOD..........    $   10.00      $   14.22
                                                -------------  -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)...................         0.05           0.13
  Net Realized and Unrealized Gain on
   Investments................................         0.61           3.99
                                                -------------  -------------
    Total from Investment Operations..........         0.66           4.12
                                                -------------  -------------
DISTRIBUTIONS
  Net Investment Income.......................           --          (0.15)
  In Excess of Net Investment Income..........           --             --
  Net Realized Gain...........................           --          (3.27)
                                                -------------  -------------
    Total Distributions.......................           --          (3.42)
                                                -------------  -------------
NET ASSET VALUE, END OF PERIOD................    $   10.66      $   14.92
                                                -------------  -------------
                                                -------------  -------------
TOTAL RETURN..................................         6.60%         29.92%
                                                -------------  -------------
                                                -------------  -------------
RATIOS AND SUPPLEMENTAL DATA:
  Net Assets, End of Period (Thousands).......    $  18,139      $   5,498
  Ratio of Expenses to Average Net Assets
   (1)........................................         0.80%**        1.05%**
  Ratio of Net Investment Income to Average
   Net Assets (1).............................         2.34%**        0.91%**
  Portfolio Turnover Rate.....................            3%           186%
  Average Commission Rate#....................          N/A        $0.0535
- ------------------------------
(1) Effect of voluntary expense limitation
    during the period:
     Per share benefit to net investment
      income..................................        $0.03          $0.01
   Ratios before expense limitation:
     Expenses to Average Net Assets...........         1.37%**        1.12%**
     Net Investment Income to Average Net
      Assets..................................         1.77%**        0.84%**
</TABLE>
    
 
   
  * Commencement of operations.
    
 
   
 ** Annualized
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
   
 # Beginning  with fiscal year  1996, the Portfolio is  required to disclose the
   average commission rate  per share  it paid  for portfolio  trades, on  which
   commissions were charged, during the period.
    
 
                                       6
<PAGE>
   
                           EMERGING GROWTH PORTFOLIO
    
   
<TABLE>
<CAPTION>
                                                                                            CLASS A
                                                                 -------------------------------------------------------------
                                                                                          YEAR ENDED
                                                                                         DECEMBER 31,
                                                                 -------------------------------------------------------------
                                                                     1996                 1995            1994            1993
                                                                 -------------   -------------   -------------   -------------
<S>                                                              <C>             <C>             <C>             <C>
NET ASSET VALUE, BEGINNING OF PERIOD...........................  $     21.49     $       16.12   $       16.22   $       16.22
                                                                 -------------   -------------   -------------   -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income Loss (1)...............................        (0.19)            (0.18)          (0.09)          (0.11)
  Net Realized and Unrealized Gain (Loss) on Investments.......         0.89              5.55           (0.01)           0.11
                                                                 -------------   -------------   -------------   -------------
    Total from Investment Operations...........................         0.70              5.37           (0.10)           0.00
                                                                 -------------   -------------   -------------   -------------
DISTRIBUTIONS
  Net Realized Gain............................................        (8.69)               --              --              --
                                                                 -------------   -------------   -------------   -------------
NET ASSET VALUE, END OF PERIOD.................................  $     13.50     $       21.49   $       16.12   $       16.22
                                                                 -------------   -------------   -------------   -------------
                                                                 -------------   -------------   -------------   -------------
TOTAL RETURN...................................................        3.72%             33.31%          (0.62)%          0.00%
                                                                 -------------   -------------   -------------   -------------
                                                                 -------------   -------------   -------------   -------------
RATIO AND SUPPLEMENTAL DATA:
  Net Assets, End of Period (Thousands)........................  $    62,793     $     119,378   $     117,669   $     103,621
  Ratio of Expenses to Average Net Assets (1)..................         1.25%             1.25%           1.25%           1.25%
  Ratio of Net Investment Income (Loss) to Average Net Assets
   (1).........................................................        (0.88)%           (0.76)%         (0.61)%         (0.77)%
  Portfolio Turnover Rate......................................           33%               25%             24%             25%
  Average Commission Rate .....................................      $0.0507               N/A             N/A             N/A
- ------------------------------
 
(1) Effect of voluntary expense limitation during the period:
     Per share benefit to net investment income................        $0.01            $0.003          $0.002           $0.01
   Ratios before expense limitation:
     Expenses to Average Net Assets............................         1.30%             1.26%           1.26%           1.31%
     Net Investment Income (Loss) to Average Net Assets........        (0.92)%           (0.77)%         (0.62)%         (0.83)%
 
<CAPTION>
                                                                                                       CLASS B
                                                                                                 -------------
                                                                                                   PERIOD FROM
                                                                    TWO MONTHS                      JANUARY 2,
                                                                         ENDED      YEAR ENDED      1996*** TO
                                                                  DECEMBER 31,     OCTOBER 31,    DECEMBER 31,
                                                                          1992            1992            1996
                                                                 -------------   -------------   -------------
<S>                                                              <C>             <C>             <C>
NET ASSET VALUE, BEGINNING OF PERIOD...........................  $     14.97     $     16.18     $     21.47
                                                                 -------------   -------------   -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income Loss (1)...............................        (0.01)          (0.09)          (0.15)
  Net Realized and Unrealized Gain (Loss) on Investments.......         1.26           (1.12)           0.82
                                                                 -------------   -------------   -------------
    Total from Investment Operations...........................         1.25           (1.21)           0.67
                                                                 -------------   -------------   -------------
DISTRIBUTIONS
  Net Realized Gain............................................           --              --           (8.69)
                                                                 -------------   -------------   -------------
NET ASSET VALUE, END OF PERIOD.................................  $     16.22     $     14.97     $     13.45
                                                                 -------------   -------------   -------------
                                                                 -------------   -------------   -------------
TOTAL RETURN...................................................         8.35%          (7.48)%          3.58%
                                                                 -------------   -------------   -------------
                                                                 -------------   -------------   -------------
RATIO AND SUPPLEMENTAL DATA:
  Net Assets, End of Period (Thousands)........................  $    94,161     $    80,156     $     3,997
  Ratio of Expenses to Average Net Assets (1)..................         1.25%**         1.25%           1.50%**
  Ratio of Net Investment Income (Loss) to Average Net Assets
   (1).........................................................        (0.68)%**       (0.66)%         (1.09)%**
  Portfolio Turnover Rate......................................            1%             17%             33%
  Average Commission Rate .....................................          N/A             N/A         $0.0507
- ------------------------------
(1) Effect of voluntary expense limitation during the period:
     Per share benefit to net investment income................        $0.00           $0.01           $0.01
   Ratios before expense limitation:
     Expenses to Average Net Assets............................         1.36%**         1.29%           1.54%**
     Net Investment Income (Loss) to Average Net Assets........        (0.79)%**       (0.71)%         (1.14)%**
</TABLE>
    
 
   
 ** Annualized.
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
   
 # Beginning  with fiscal year  1996, the Portfolio is  required to disclose the
   average commission rate  per share  it paid  for portfolio  trades, on  which
   commissions were charged, during the period.
    
 
                                       7
<PAGE>
   
                          AGGRESSIVE EQUITY PORTFOLIO
    
 
   
<TABLE>
<CAPTION>
                                                                                                           CLASS B
                                                                                 CLASS A               -------------
                                                                     --------------------------------  PERIOD FROM
                                                                                      PERIOD FROM       JANUARY 2,
                                                                      YEAR ENDED    MARCH 8, 1995*      1996*** TO
                                                                     DECEMBER 31,   TO DECEMBER 31,    DECEMBER 31,
                                                                            1996             1995             1996
                                                                     -------------  -----------------  -------------
<S>                                                                  <C>            <C>                <C>
NET ASSET VALUE, BEGINNING OF PERIOD...............................    $   12.17        $   10.00        $   12.25
                                                                     -------------        -------      -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)........................................         0.18             0.15             0.13
  Net Realized and Unrealized Gain on Investments..................         4.73             3.95             4.67
                                                                     -------------        -------      -------------
    Total from Investment Operations...............................         4.91             4.10             4.80
                                                                     -------------        -------      -------------
DISTRIBUTIONS
  Net Investment Income............................................        (0.17)           (0.15)           (0.15)
  Net Realized Gain................................................        (2.48)           (1.78)           (2.48)
                                                                     -------------        -------      -------------
    Total Distributions............................................        (2.65)           (1.93)           (2.63)
                                                                     -------------        -------      -------------
NET ASSET VALUE, END OF PERIOD.....................................    $   14.43        $   12.17        $   14.42
                                                                     -------------        -------      -------------
                                                                     -------------        -------      -------------
TOTAL RETURN.......................................................        40.90%           41.25%           39.72%
                                                                     -------------        -------      -------------
                                                                     -------------        -------      -------------
RATIO AND SUPPLEMENTAL DATA:
  Net Assets, End of Period (Thousands)............................    $  68,480        $  28,548        $   8,805
  Ratio of Expenses to Average Net Assets (1)......................         1.00%            1.00%**          1.25%**
  Ratio of Net Investment Income to Average Net Assets (1).........         1.26%            1.64%**          0.95%**
  Portfolio Turnover Rate..........................................          380%             309%             380%
  Average Commission Rate#.........................................      $0.0484                  N/A        $0.0484
</TABLE>
    
 
- ------------------
 
   
<TABLE>
<C>  <S>                                                           <C>            <C>            <C>
(1)  Effect of voluntary expense limitation during the period:
       Per share benefit to net investment income................        $0.03          $0.06          $0.03
     Ratios before expense limitation:
       Expenses to Average Net Assets............................         1.24%          1.59%**        1.47%**
       Net Investment Income to Average Net Assets...............         1.02%          1.05%**        0.73%**
</TABLE>
    
 
   
  * Commencement of operations.
    
 
   
 ** Annualized.
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
   
 # Beginning  with fiscal year  1996, the Portfolio is  required to disclose the
   average commission rate  per share  it paid  for portfolio  trades, on  which
   commissions were charged, during the period.
    
 
                                       8
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
 
    The   Fund  consists  of   twenty-nine  portfolios,  offering  institutional
investors and high net  worth individual investors a  broad range of  investment
choices coupled with the advantages of a no-load mutual fund with Morgan Stanley
and  its affiliates providing customized  services as Adviser, Administrator and
Distributor. Each portfolio offers Class  A shares and except the  International
Small  Cap, Money Market  and Municipal Money Market  Portfolios, offers Class B
shares. Each portfolio has its own investment objective and policies designed to
meet its specific goals. The investment objective of each Portfolio described in
this Prospectus is as follows:
 
    - The EQUITY  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation  by
      investing  in  growth-oriented  equity  securities  of  medium  and  large
      capitalization companies.
 
    - The EMERGING  GROWTH PORTFOLIO  seeks  long-term capital  appreciation  by
      investing  primarily  in growth-oriented  equity  securities of  small- to
      medium-sized corporations.
 
    - The MICROCAP PORTFOLIO seeks  long-term capital appreciation by  investing
      primarily in growth-oriented equity securities of small corporations.
 
    - The  AGGRESSIVE EQUITY  PORTFOLIO seeks capital  appreciation by investing
      primarily in corporate equity and equity-linked securities.
 
    The other portfolios of the Fund  are described in other Prospectuses  which
may be obtained from the Fund at the address and phone number noted on the cover
page of this Prospectus. The investment objectives of these other portfolios are
listed below:
 
    GLOBAL AND INTERNATIONAL EQUITY:
 
    - The   ACTIVE   COUNTRY  ALLOCATION   PORTFOLIO  seeks   long-term  capital
      appreciation by investing in accordance with country weightings determined
      by the Adviser  in equity  securities of  non-U.S. issuers  which, in  the
      aggregate, replicate broad country indices.
 
    - The  ASIAN  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
      investing primarily in equity securities of Asian issuers.
 
    - The CHINA GROWTH PORTFOLIO seeks to provide long-term capital appreciation
      by investing primarily  in equity  securities of issuers  in The  People's
      Republic of China, Hong Kong and Taiwan.
 
    - The  EMERGING MARKETS  PORTFOLIO seeks  long-term capital  appreciation by
      investing primarily in equity securities of emerging country issuers.
 
    - The EUROPEAN  EQUITY PORTFOLIO  seeks  long-term capital  appreciation  by
      investing primarily in equity securities of European issuers.
 
    - The  GLOBAL  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation by
      investing primarily in equity securities of issuers throughout the  world,
      including U.S. issuers.
 
    - The  GOLD  PORTFOLIO  seeks long-term  capital  appreciation  by investing
      primarily in equity securities of foreign and domestic issuers engaged  in
      gold-related activities.
 
    - The INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation by
      investing primarily in equity securities of non-U.S. issuers.
 
                                       9
<PAGE>
    - The INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation by
      investing  primarily in equity securities of non-U.S. issuers domiciled in
      EAFE countries.
 
    - The INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital appreciation
      by investing  primarily  in equity  securities  of non-U.S.  issuers  with
      equity market capitalizations of less than $1 billion.
 
    - The  JAPANESE  EQUITY PORTFOLIO  seeks  long-term capital  appreciation by
      investing primarily in equity securities of Japanese issuers.
 
   
    - The LATIN  AMERICAN  PORTFOLIO  seeks long-term  capital  appreciation  by
      investing  primarily in equity  securities of Latin  American issuers and,
      from time to time, debt securities issued or guaranteed by Latin  American
      governments or governmental entities.
    
 
    U.S. EQUITY:
 
    - The  SMALL CAP VALUE EQUITY PORTFOLIO seeks high long-term total return by
      investing in  undervalued  equity  securities of  small-  to  medium-sized
      companies.
 
    - The TECHNOLOGY PORTFOLIO seeks long-term capital appreciation by investing
      primarily  in equity securities  of companies that, in  the opinion of the
      Portfolio's  investment  adviser,  are  expected  to  benefit  from  their
      involvement in technology and technology-related industries.
 
    - The  U. S.  REAL ESTATE PORTFOLIO  seeks to provide  above average current
      income and long-term capital appreciation by investing primarily in equity
      securities of companies in the  U.S. real estate industry, including  real
      estate investment trusts.
 
    - The  VALUE EQUITY PORTFOLIO seeks high total return by investing in equity
      securities which the Adviser  believes to be  undervalued relative to  the
      stock market in general at the time of purchase.
 
    EQUITY AND FIXED INCOME:
 
    - The BALANCED PORTFOLIO seeks high total return while preserving capital by
      investing  in  a combination  of undervalued  equity securities  and fixed
      income securities.
 
    FIXED INCOME:
 
    - The EMERGING MARKETS DEBT PORTFOLIO  seeks high total return by  investing
      primarily   in  debt  securities  of  government,  government-related  and
      corporate issuers located in emerging countries.
 
    - The FIXED INCOME PORTFOLIO seeks to produce a high total return consistent
      with the preservation of capital  by investing in a diversified  portfolio
      of fixed income securities.
 
    - The GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real rate
      of return while preserving capital by investing in fixed income securities
      of issuers throughout the world, including U.S. issuers.
 
    - The  HIGH YIELD PORTFOLIO seeks to maximize total return by investing in a
      diversified portfolio of high yield  fixed income securities that offer  a
      yield  above  that generally  available on  debt  securities in  the three
      highest rating categories of the recognized rating services.
 
    - The MORTGAGE-BACKED SECURITIES PORTFOLIO seeks to produce as high a  level
      of  current income  as is consistent  with the preservation  of capital by
      investing primarily  in  a  variety  of  investment-grade  mortgage-backed
      securities.
 
                                       10
<PAGE>
    - The  MUNICIPAL BOND  PORTFOLIO seeks  to produce  a high  level of current
      income consistent with preservation of principal by investing primarily in
      municipal obligations, the interest on which is exempt from federal income
      tax.
 
    MONEY MARKET:
 
    - The MONEY MARKET PORTFOLIO seeks  to maximize current income and  preserve
      capital  while maintaining high  levels of liquidity  through investing in
      high quality money  market instruments  with remaining  maturities of  one
      year or less.
 
    - The  MUNICIPAL MONEY MARKET PORTFOLIO seeks to maximize current tax-exempt
      income and preserve  capital while  maintaining high  levels of  liquidity
      through  investing in high quality money market instruments with remaining
      maturities of one year or less  which are exempt from federal income  tax.
     THE  CHINA GROWTH,  MICROCAP AND MORTGAGE-BACKED  SECURITIES PORTFOLIOS ARE
      CURRENTLY NOT BEING OFFERED.
 
INVESTMENT MANAGEMENT
 
   
    Morgan Stanley Asset Management  Inc., a wholly  owned subsidiary of  Morgan
Stanley  Group  Inc.,  which,  together  with  its  affiliated  asset management
companies, at March  31, 1997  had in  excess of  $118 billion  in assets  under
management  as  an  investment  manager  or  as  a  fiduciary  adviser,  acts as
investment adviser to the  Fund and each of  its portfolios. See "Management  of
the Fund -- Investment Adviser" and "Management of the Fund -- Administrator."
    
 
HOW TO INVEST
 
    Class  A shares of each  Portfolio are offered directly  to investors at net
asset value with no sales  commission or 12b-1 charges.  Class B shares of  each
Portfolio  are offered at net  asset value with no  sales commission, but with a
12b-1 fee, which  is accrued daily  and paid  quarterly, equal to  0.25% of  the
Class B shares' average daily net assets on an annualized basis. Share purchases
may  be  made  by  sending  investments directly  to  the  Fund  or  through the
Distributor. The minimum initial investment, generally, is $500,000 for Class  A
shares  of each Portfolio and $100,000 for Class B shares of each Portfolio. The
minimum  initial  investment  amount  is  reduced  for  certain  categories   of
investors.  For additional  information on  how to  purchase shares  and minimum
initial investments, see "Purchase of Shares."
 
HOW TO REDEEM
 
    Shares of each Portfolio may be redeemed  at any time, without cost, at  the
net  asset value  per share  of shares of  the applicable  class next determined
after receipt of  the redemption request.  The redemption price  may be more  or
less  than the purchase  price. Certain redemptions  that cause the  value of an
account to remain for  a continuous 60-day period  below the minimum  investment
amount  for  Class A  shares or  for Class  B shares  may result  in involuntary
redemption or automatic conversion. For additional information on how to  redeem
shares  and involuntary  redemption or  conversion, see  "Purchase of  Shares --
Minimum Account Sizes and Involuntary  Redemption of Shares" and "Redemption  of
Shares."
 
RISK FACTORS
 
    The   investment  policies  of  the  Portfolios  entail  certain  risks  and
considerations of which an investor should be aware. Because the Emerging Growth
and   MicroCap    Portfolios   seek    long-term   capital    appreciation    by
 
                                       11
<PAGE>
   
investing  primarily in  small- to  medium-sized companies  and small companies,
respectively, both of which types of companies are more vulnerable to  financial
and  other risks than  larger, more established  companies, investments in these
Portfolios may involve  a higher degree  of risk and  price volatility than  the
general  equity markets. The Aggressive Equity  Portfolio may invest in small-to
medium-sized companies  to  a  lesser  extent.  Each  Portfolio  may  invest  in
securities  of foreign issuers, which are subject to certain risks not typically
associated with domestic securities. In  addition, the Portfolios may invest  in
Depositary Receipts, money market instruments, repurchase agreements, lend their
portfolio  securities and  may purchase securities  on a  when-issued or delayed
delivery basis. The Equity Growth and Aggressive Equity Portfolios may invest in
non-publicly  traded  securities,  private  placements,  restricted  securities,
covered  call options  and may invest  in foreign currency  forward contracts to
hedge currency risk  associated with investment  in non-U.S.  dollar-denominated
securities.  The Equity  Growth and Aggressive  Equity Portfolios  may invest in
certain derivatives, including  options, futures and  options on futures.  These
investments  entail  certain costs  and  risks, including  imperfect correlation
between the  value of  securities  held by  a Portfolio  and  the value  of  the
particular  derivative instrument, and the risk that a Portfolio could not close
out a derivatives  position when it  would be  most advantageous to  do so.  The
Aggressive  Equity Portfolio may  sell securities short  and invest in specialty
equity-linked securities,  such as  PERCS, ELKS  or  LYONs, of  U.S. and,  to  a
limited  extent, foreign issuers,  which may involve risks  in addition to those
associated with  other equity  securities. The  MicroCap and  Aggressive  Equity
Portfolios  are non-diversified portfolios  under the Investment  Company Act of
1940, as amended (the "1940 Act") and therefore may invest a greater  proportion
of  their assets in the securities of a  smaller number of issuers and may, as a
result, be subject to greater risk  with respect to their portfolio  securities.
Each  of these investment strategies involves specific risks which are described
under  "Investment   Objectives  and   Policies"  and   "Additional   Investment
Information"  herein  and  under  "Investment Objectives  and  Policies"  in the
Statement of Additional Information.
    
 
                                       12
<PAGE>
                       INVESTMENT OBJECTIVES AND POLICIES
 
    The investment objective of each Portfolio is described below, together with
the policies the Portfolios employ in their efforts to achieve these objectives.
Each Portfolio's investment objective is a  fundamental policy which may not  be
changed without the approval of a majority of the Portfolio's outstanding voting
securities.  There  is  no  assurance  that  the  Portfolios  will  attain their
objectives. In addition to the  investments and strategies described below,  the
Portfolios  may invest  in certain  securities and  obligations as  set forth in
"Additional Investment  Information" below  and as  described under  "Investment
Objectives  and  Policies"  in  the  Statement  of  Additional  Information. The
investment policies  described below  are not  fundamental policies  and may  be
changed without shareholder approval.
 
THE EQUITY GROWTH PORTFOLIO
 
    The  Portfolio's  investment  objective  is  to  provide  long-term  capital
appreciation by investing  in growth-oriented  equity securities  of medium  and
large  capitalization  U.S.  corporations  and,  to  a  limited  extent, foreign
corporations. With respect  to the Portfolio,  equity securities include  common
and preferred stocks, convertible securities and rights and warrants to purchase
common  stocks. Under normal  circumstances, the Portfolio  will invest at least
65% of the value of its total assets in equity securities.
 
    The Adviser employs a flexible and eclectic investment process in pursuit of
the Portfolio's investment  objectives. In selecting  stocks for the  Portfolio,
the  Adviser  concentrates  on  a  universe  of  rapidly  growing,  high quality
companies and lower, but accelerating, earnings growth situations. The Adviser's
universe of  potential investments  generally  comprises companies  with  market
capitalizations  of $500  million or  more. The  Portfolio is  not restricted to
investments  in  specific  market  sectors.   The  Adviser  uses  its   research
capabilities, analytical resources and judgment to assess economic, industry and
market  trends, as well as individual  company developments, to select promising
growth investments for the Portfolio. The Adviser concentrates on companies with
strong, communicative managements and clearly defined strategies for growth.  In
addition,  the  Adviser  rigorously  assesses  company  developments,  including
changes in strategic direction, management  focus and current and likely  future
earnings  results. Valuation is  important to the  Adviser but is  viewed in the
context of  prospects for  sustainable  earnings growth  and the  potential  for
positive  earnings surprises vis-a-vis consensus  expectations. The Portfolio is
free to invest in any equity security that, in the Adviser's judgment,  provides
above average potential for capital appreciation.
 
    In   selecting  investments  for  the   Portfolio,  the  Adviser  emphasizes
individual security  selection. The  Portfolio's investments  will generally  be
diversified  by number  of issues but  concentrated sector  positions may result
from  the  investment  process.  The   Portfolio  has  a  long-term   investment
perspective; however, the Adviser may take advantage of short-term opportunities
that are consistent with the Portfolio's objective by selling recently purchased
securities which have increased in value.
 
    The  Portfolio may  invest up  to 25%  of its  total assets  at the  time of
purchase in  securities  of  foreign  companies. The  Portfolio  may  invest  in
securities  of foreign issuers  directly or in the  form of Depositary Receipts.
Investors should recognize that investing in foreign companies involves  certain
special considerations which are not typically associated with investing in U.S.
companies.
 
    The  Portfolio may invest in convertible securities of domestic and, subject
to the above  restrictions, foreign  issuers on  occasions when,  due to  market
conditions,  it  is  more  advantageous  to  purchase  such  securities  than to
 
                                       13
<PAGE>
purchase common stock.  Since the Portfolio  invests in both  common stocks  and
convertible securities, the risks of investing in the general equity markets may
be tempered to a degree by the Portfolio's investments in convertible securities
which are often not as volatile as common stock.
 
THE EMERGING GROWTH PORTFOLIO
 
    The  Portfolio's  investment  objective  is  to  provide  long-term  capital
appreciation by  investing primarily  in  growth-oriented equity  securities  of
small-  to  medium-sized  domestic  corporations and,  to  a  limited  extent as
described below, foreign corporations. The  production of any current income  is
incidental  to  this  objective.  Such  companies  generally  have  annual gross
revenues ranging  from  $10  million  to  $750  million.  With  respect  to  the
Portfolio,  equity securities  include common and  preferred stocks, convertible
securities, and rights and warrants to  purchase common stocks, and any  similar
equity  interest, such as trust or partnership interests. Such equity securities
may not pay dividends or distributions and may or may not carry voting rights.
 
    The Adviser  employs  a  flexible  investment  program  in  pursuit  of  the
Portfolio's investment objective. The Portfolio is not restricted to investments
in  specific market sectors. The Portfolio will invest in small- to medium-sized
companies that  are early  in their  life  cycle, but  which, in  the  Adviser's
judgment,  have the potential to become  major enterprises. The Adviser uses its
judgment and  research capabilities  to assess  economic, industry,  market  and
company   developments  to  select  investments  in  promising  emerging  growth
companies that are expected  to benefit from new  technology or new products  or
services.  In  addition, the  Adviser looks  for  special developments,  such as
research discoveries,  changes in  customer  demand, rejuvenated  management  or
basic   changes  in  the   economic  environment.  These   situations  are  only
illustrative of the types of investments  the Portfolio may make. The  Portfolio
is free to invest in any common stock which, in the Adviser's judgment, provides
above-average potential for capital appreciation.
 
    The  Portfolio intends to manage its  investments actively to accomplish its
investment  objective.   Since  the   Portfolio  has   a  long-term   investment
perspective,  the  Adviser  does  not intend  to  respond  to  short-term market
fluctuations or to  acquire securities  for the purpose  of short-term  trading;
however,  the Adviser  may take advantage  of short-term  opportunities that are
consistent with its objective.
 
    The Portfolio  may invest  up to  25% of  its total  assets at  the time  of
purchase  in  securities  of  foreign companies.  The  Portfolio  may  invest in
securities of foreign issuers  directly or in the  form of Depositary  Receipts.
The  Portfolio may enter  into foreign currency  forward contracts which provide
for the purchase or sale of foreign currencies in connection with the settlement
of foreign securities transactions or to hedge the underlying currency  exposure
related  to  foreign  investments.  The  Portfolio  will  not  enter  into these
commitments for speculative purposes. Investors should recognize that  investing
in  foreign  companies involves  certain  special considerations  which  are not
typically associated with investing in U.S. companies.
 
    The Portfolio may  also invest  in convertible securities  of domestic  and,
subject  to the  above restrictions, foreign  issuers on occasions  when, due to
market conditions, it is more advantageous  to purchase such securities than  to
purchase common stock. The Portfolio will not invest in debt securities that are
not  rated at least investment  grade by either Standard  & Poor's Ratings Group
("S&P") or  Moody's Investors  Service, Inc.  ("Moody's"). Since  the  Portfolio
invests in both common stocks and convertible securities, the risks of investing
in  the general equity  markets may be  tempered to a  degree by the Portfolio's
investments in convertible securities, which are often not as volatile as equity
securities.
 
                                       14
<PAGE>
THE MICROCAP PORTFOLIO
 
    The  Portfolio's  investment  objective  is  to  provide  long-term  capital
appreciation  by  investing primarily  in  growth-oriented equity  securities of
small domestic corporations and, to a limited extent as described below, foreign
corporations. The  production  of  any  current income  is  incidental  to  this
objective.  Such companies  generally have,  at time  of purchase,  annual gross
revenues of $150 million  or less or market  capitalizations of $250 million  or
less.  With  respect  to the  Portfolio,  equity securities  include  common and
preferred stocks, convertible securities, rights and warrants to purchase common
stocks, and any similar equity interest, such as trust or partnership interests.
Such equity securities may or may not pay dividends or distributions and may  or
may not carry voting rights.
 
    The  Adviser  employs  a  flexible  investment  program  in  pursuit  of the
Portfolio's investment objective. The Portfolio is not restricted to investments
in specific  market sectors.  The Portfolio  will invest  in equity  securities,
including  securities purchased in initial  public offerings, of small companies
that are early in their life cycle, but which, in the Adviser's judgement,  have
the  potential to achieve  long-term capital appreciation.  The Adviser uses its
judgment and  research capabilities  to assess  economic, industry,  market  and
company  developments  to select  investments  in promising  companies  that are
expected to  benefit  from  new  technology or  new  products  or  services.  In
addition,   the  Adviser  looks  for  special  developments,  such  as  research
discoveries, changes in customer demand, rejuvenated management or basic changes
in the economic environment. These situations are only illustrative of the types
of investments the Portfolio may  make. The Portfolio is  free to invest in  any
equity security which in the Adviser's judgment provides above-average potential
for capital appreciation.
 
    The  Portfolio intends to manage its  investments actively to accomplish its
investment  objective.   Since  the   Portfolio  has   a  long-term   investment
perspective,  the  Adviser  does  not intend  to  respond  to  short-term market
fluctuations or to  acquire securities  for the purpose  of short-term  trading;
however,  the Adviser  may take advantage  of short-term  opportunities that are
consistent with its objective.
 
    The Portfolio  may invest  up to  25% of  its total  assets at  the time  of
purchase  in securities of  foreign companies. The Portfolio  may invest in such
securities of foreign issuers  directly or in the  form of Depositary  Receipts.
The  Portfolio may enter  into foreign currency  forward contracts which provide
for the purchase or sale of foreign currencies in connection with the settlement
of foreign securities transactions or to hedge the underlying currency  exposure
related  to  foreign  investments.  The  Portfolio  will  not  enter  into these
commitments for speculative purposes. Investors should recognize that  investing
in  foreign  companies involves  certain  special considerations  which  are not
typically associated with investing in U.S. companies.
 
    The Portfolio may invest in convertible securities of domestic and,  subject
to  the above  restrictions, foreign  issuers on  occasions when,  due to market
conditions, it is more advantageous to purchase such securities than to purchase
common stock. The  Portfolio will  not invest in  debt securities  that are  not
rated  at least investment grade  by either S&P or  Moody's. Since the Portfolio
invests in both common stocks and convertible securities, the risks of investing
in the general equity  markets may be  tempered to a  degree by the  Portfolio's
investments in convertible securities, which are often not as volatile as equity
securities.
 
THE AGGRESSIVE EQUITY PORTFOLIO
 
    The  Portfolio's investment objective is  to provide capital appreciation by
investing primarily  in  a non-diversified  portfolio  of corporate  equity  and
equity-linked   securities.   With  respect   to   the  Portfolio,   equity  and
equity-linked  securities  include  common  and  preferred  stocks,  convertible
securities, rights and warrants to
 
                                       15
<PAGE>
purchase  common  stocks, options,  futures, and  specialty securities,  such as
ELKS, LYONs, PERCS  of U.S.,  and to a  limited extent,  foreign issuers.  Under
normal circumstances, the Portfolio will invest at least 65% of the value of its
total assets in equity and equity-linked securities.
 
    The Adviser employs a flexible and eclectic investment process in pursuit of
the Portfolio's investment objective. In selecting securities for the Portfolio,
the  Adviser  concentrates  on  a  universe  of  rapidly  growing,  high quality
companies and lower, but accelerating, earnings growth situations. The Adviser's
universe of  potential investments  generally  comprises companies  with  market
capitalizations  of  $500 million  or  more, but  smaller  market capitalization
securities may be purchased from time  to time. The Portfolio is not  restricted
to  investments  in  specific  market sectors.  The  Adviser  uses  its research
capabilities, analytical resources and judgment to assess economic, industry and
market trends, as well as  individual company developments, to select  promising
investments  for  the  Portfolio.  The Adviser  concentrates  on  companies with
strong, communicative managements and clearly defined strategies for growth.  In
addition,  the Adviser rigorously  assesses earnings results.  The Adviser seeks
companies which will deliver surprisingly  strong earnings growth. Valuation  is
of secondary importance to the Adviser and is viewed in the context of prospects
for  sustainable  earnings  growth  and  the  potential  for  positive  earnings
surprises in relation to consensus expectations. The Portfolio is free to invest
in any  equity  or  equity-linked  security that,  in  the  Adviser's  judgment,
provides above average potential for capital appreciation.
 
    In   selecting  investments  for  the   Portfolio,  the  Adviser  emphasizes
individual  security  selection.  Overweighted   sector  positions  and   issuer
positions  may result from the investment process. The Portfolio has a long-term
investment perspective; however,  the Adviser may  take advantage of  short-term
opportunities  that  are consistent  with the  Portfolio's objective  by selling
recently purchased securities which have increased in value.
 
    The Portfolio may invest in equity and equity-linked securities of  domestic
and  foreign corporations. However, the Portfolio does not expect to invest more
than 25% of its total  assets at the time of  purchase in securities of  foreign
companies. The Portfolio may invest in securities of foreign issuers directly or
in  the form of  Depositary Receipts. The  Portfolio may also  invest in foreign
currency forward contracts. Investors should recognize that investing in foreign
companies involves  certain  special  considerations  which  are  not  typically
associated with investing in U.S. companies.
 
                       ADDITIONAL INVESTMENT INFORMATION
 
CONVERTIBLE SECURITIES, WARRANTS AND EQUITY-LINKED SECURITIES.
 
    The  Portfolios  may invest  in securities  such as  convertible securities,
preferred  stock,  warrants  or  other  securities  exchangeable  under  certain
circumstances  for  shares  of  common stock.  Warrants  are  instruments giving
holders the right, but not the obligation, to buy shares of a company at a given
price during a specified period.
 
    The Aggressive  Equity Portfolio  may  invest in  equity-linked  securities,
including,  among others,  PERCS, ELKS or  LYONs, which are  securities that are
convertible into  or the  value of  which is  based upon  the value  of,  equity
securities upon certain terms and conditions. The amount received by an investor
at  maturity of such  securities is not fixed  but is based on  the price of the
underlying common stock. It  is impossible to predict  whether the price of  the
underlying  common stock  will rise  or fall.  Trading prices  of the underlying
common stock will be influenced by the issuer's operational results, by complex,
interrelated political, economic,
 
                                       16
<PAGE>
financial, or other factors affecting  the capital markets, the stock  exchanges
on  which the underlying common stock is  traded and the market segment of which
the issuer  is  a  part.  In  addition,  it  is  not  possible  to  predict  how
equity-linked  securities will  trade in the  secondary market,  which is fairly
developed and liquid. The  market for such securities  may be shallow,  however,
and high volume trades may be possible only with discounting. In addition to the
foregoing  risks, the return on such  securities depends on the creditworthiness
of the issuer  of the  securities, which  may be  the issuer  of the  underlying
securities   or  a   third  party  investment   banker  or   other  lender.  The
creditworthiness of such third party issuer of equity-linked securities may, and
often does,  exceed  the  creditworthiness  of  the  issuer  of  the  underlying
securities.  The advantage  of using  equity-linked securities  over traditional
equity and debt securities is that the former are income producing vehicles that
may provide a higher  income than the dividend  income on the underlying  equity
securities  while allowing some participation in the capital appreciation of the
underlying  equity  securities.   Another  advantage   of  using   equity-linked
securities  is that they may be used for hedging to reduce the risk of investing
in the generally more volatile underlying equity securities.
 
    The following are three examples of equity-linked securities. The  Portfolio
may  invest in  the securities  described below  or other  similar equity-linked
securities.
 
    PERCS.  Preferred Equity  Redemption Cumulative Stock ("PERCS")  technically
is  preferred  stock  with  some  characteristics  of  common  stock.  PERCS are
mandatorily convertible into common stock after a period of time, usually  three
years,  during which  the investors' capital  gains are capped,  usually at 30%.
Commonly, PERCS may be  redeemed by the  issuer at any time  or if the  issuer's
common  stock is trading  at a specified  price level or  better. The redemption
price starts at the beginning  of the PERCS duration period  at a price that  is
above  the cap by the amount of the extra dividends the PERCS holder is entitled
to receive relative  to the  common stock  over the  duration of  the PERCS  and
declines  to the cap price shortly before maturity of the PERCS. In exchange for
having the cap on capital gains and  giving the issuer the option to redeem  the
PERCS  at any time or  at the specified common  stock price level, the Portfolio
may be compensated with a substantially  higher dividend yield than that on  the
underlying  common stock.  Investors, such as  the Portfolio,  that seek current
income find PERCS attractive because PERCS provide a higher dividend income than
that paid with respect to a company's common stock.
 
    ELKS.    Equity-Linked  Securities   ("ELKS")  differ  from  ordinary   debt
securities,  in that the principal amount received  at maturity is not fixed but
is based on the  price of the  issuer's common stock.  ELKS are debt  securities
commonly  issued in  fully registered form  for a  term of three  years under an
indenture trust. At maturity, the holder of  ELKS will be entitled to receive  a
principal  amount equal to the lesser of a  cap amount, commonly in the range of
30% to 55% greater than the current  price of the issuer's common stock, or  the
average  closing  price  per share  of  the  issuer's common  stock,  subject to
adjustment as  a result  of certain  dilution events,  for the  10 trading  days
immediately  prior to maturity.  Unlike PERCS, ELKS are  commonly not subject to
redemption prior to maturity. ELKS  usually bear interest during the  three-year
term  at a substantially higher  rate than the dividend  yield on the underlying
common stock. In exchange for having the cap on the return that might have  been
received  as capital gains on the underlying  common stock, the Portfolio may be
compensated with the higher yield, contingent on how well the underlying  common
stock  does. Investors,  such as the  Portfolio, that seek  current income, find
ELKS attractive because  ELKS provide a  higher dividend income  than that  paid
with respect to a company's common stock.
 
                                       17
<PAGE>
    LYONS.    Liquid  Yield Option  Notes  ("LYONs") differ  from  ordinary debt
securities, in that the amount  received prior to maturity  is not fixed but  is
based  on the price  of the issuer's  common stock. LYONs  are zero-coupon notes
that sell at a large discount from  face value. For an investment in LYONs,  the
Portfolio  will  not  receive  any interest  payments  until  the  notes mature,
typically in 15 to 20 years, when the notes are redeemed at face, or par, value.
The yield on LYONs, typically, is lower-than-market rate for debt securities  of
the  same maturity, due in part to the  fact that the LYONs are convertible into
common stock of the issuer at any time at the option of the holder of the LYONs.
Commonly, the LYONs are redeemable  by the issuer at  any time after an  initial
period  or if the issuer's common stock is trading at a specified price level or
better or, at the option of the holder, upon certain fixed dates. The redemption
price typically is the purchase price  of the LYONs plus accrued original  issue
discount  to  the date  of redemption,  which  amounts to  the lower-than-market
yield. The Portfolio will  receive only the  lower-than-market yield unless  the
underlying  common stock  increases in  value at  a substantial  rate. LYONs are
attractive to  investors like  the  Portfolio when  it  appears that  they  will
increase in value due to the rise in value of the underlying common stock.
 
   
    DEPOSITARY  RECEIPTS.   The  Portfolios may  invest in  Depositary Receipts,
including American  Depositary  Receipts ("ADRs"),  Global  Depositary  Receipts
("GDRs"),  European Depositary  Receipts ("EDRs") and  other Depositary Receipts
(which, together with ADRs, GDRs and EDRs, are hereinafter collectively referred
to as "Depositary Receipts"), to the extent that such Depositary Receipts are or
become available.  ADRs are  securities, typically  issued by  a U.S.  financial
institution (a "depositary"), that evidence ownership interests in a security or
a  pool of securities issued  by a foreign issuer  (the "underlying issuer") and
deposited with the depositary. ADRs  include American Depositary Shares and  New
York  Shares  and  may  be  "sponsored"  or  "unsponsored."  Sponsored  ADRs are
established  jointly  by  a  depositary  and  the  underlying  issuer,   whereas
unsponsored ADRs may be established by a depositary without participation by the
underlying  issuer.  The  issuers  of  the stock  of  unsponsored  ADRs  are not
obligated to disclose material information  in the United States and  therefore,
there  may not be a correlation between such information and the market value of
the ADR. GDRs, EDRs and other types of Depositary Receipts are typically  issued
by  foreign depositaries, although they may also be issued by U.S. depositaries,
and evidence ownership interests in a  security or pool of securities issued  by
either  a  foreign  or a  U.S.  corporation. Generally,  Depositary  Receipts in
registered form  are  designed  for  use  in  the  U.S.  securities  market  and
Depositary  Receipts in bearer  form are designed for  use in securities markets
outside  the  United  States.  The  Portfolios  may  invest  in  sponsored   and
unsponsored  Depositary  Receipts. For  purposes  of the  Portfolios' investment
policies, the Portfolios' investments in  Depositary Receipts will be deemed  to
be investments in the underlying securities.
    
 
   
    FOREIGN  CURRENCY FORWARD CONTRACTS.  Each  Portfolio may enter into foreign
currency forward contracts ("forward contracts")  that provide for the  purchase
or  sale of an amount  of a specified currency at  a future date. The Portfolios
may use  such contracts  to protect  against  a decline  in a  foreign  currency
against  the U.S.  dollar between  the trade date  and settlement  date when the
Portfolio purchases  or sells  securities,  lock in  the  U.S. dollar  value  of
dividends  and interest  on securities held  by the Portfolio,  and generally to
protect the  U.S. dollar  value  of securities  held  by the  Portfolio  against
exchange  rate fluctuation. While forward contracts may limit losses as a result
of exchange  rate  fluctuations, they  will  also  limit any  gains  that  might
otherwise have been realized. The Portfolio's Custodian may be required to place
cash  or liquid  securities in a  segregated account  in an amount  equal to the
value of the Portfolio's total assets  committed to the consummation of  forward
contracts.
    
 
                                       18
<PAGE>
If  the  value of  the  securities placed  in  the segregated  account declines,
additional cash or securities will be placed in the account on a daily basis  so
that  the value  of the  account will  be at  least equal  to the  amount of the
Portfolio's commitments with respect to such contracts.
 
    FOREIGN INVESTMENT.   The Portfolios may  invest in U.S.  dollar-denominated
securities  of foreign  issuers trading in  U.S. markets and  each Portfolio may
invest in non-U.S. dollar-denominated securities of foreign issuers.  Investment
in  securities of foreign  issuers involves somewhat  different investment risks
than those affecting securities of U.S.  domestic issuers. There may be  limited
publicly  available  information with  respect to  foreign issuers,  and foreign
issuers are not generally subject to uniform accounting, auditing and  financial
standards  and requirements  comparable to  those applicable  to U.S. companies.
There may  also  be  less  government  supervision  and  regulation  of  foreign
securities  exchanges, brokers and  listed companies than  in the United States.
Many foreign  securities  markets  have  substantially  less  volume  than  U.S.
national  securities exchanges, and securities of  some foreign issuers are less
liquid and  more  volatile  than  securities  of  comparable  domestic  issuers.
Brokerage   commissions  and  other  transaction  costs  on  foreign  securities
exchanges are generally higher than in the United States. Dividends and interest
paid by foreign issuers may be  subject to withholding and other foreign  taxes,
which  may  decrease  the  net  return on  foreign  investments  as  compared to
dividends and interest paid  to the Portfolio by  domestic companies. It is  not
expected  that a Portfolio or  its shareholders would be  able to claim a credit
for U.S. tax purposes with respect  to any such foreign taxes. Additional  risks
include  future  political and  economic  developments, the  possibility  that a
foreign jurisdiction might impose or change withholding taxes on income  payable
with  respect  to  foreign  securities,  possible  seizure,  nationalization  or
expropriation of  the  foreign  issuer  or foreign  deposits  and  the  possible
adoption  of foreign governmental restrictions  such as exchange controls. Also,
it may be more  difficult to obtain  a judgement in a  court outside the  United
States.
 
    Investments  in securities of foreign  issuers are frequently denominated in
foreign  currencies  and,  since  the  Portfolios  may  also  temporarily   hold
uninvested  reserves in  bank deposits in  foreign currencies, the  value of the
Portfolios' assets  measured  in  U.S.  dollars may  be  affected  favorably  or
unfavorably  by  changes  in currency  exchange  rates and  in  exchange control
regulations, and the Portfolios may  incur costs in connection with  conversions
between various currencies.
 
   
FUTURES CONTRACTS AND OPTIONS ON FUTURES CONTRACTS.
    
 
   
    The Equity Growth and the Aggressive Equity Portfolios may purchase and sell
futures contracts and options on futures contracts, including but not limited to
financial  futures, securities index futures, foreign currency exchange futures,
and interest rate futures contracts. Futures  contracts provide for the sale  by
one  party and  purchase by another  party of  a specified amount  of a specific
security, instrument  or basket  thereof, at  a specific  future date  and at  a
specified  price. An option on a futures contract is a legal contract that gives
the holder the right to buy or sell a specified amount of futures contracts at a
fixed or determinable price upon the exercise of the option.
    
 
   
    The Portfolios may  sell securities index  futures contracts and/or  options
thereon  in anticipation of or during a  market decline to attempt to offset the
decrease in market value of investments in its portfolio, or purchase securities
index futures in order to gain market exposure. Subject to applicable laws,  the
Portfolios may engage in transactions in securities index futures contracts (and
options  thereon)  which  are  traded  on  a  recognized  securities  or futures
exchange, or  may purchase  or  sell such  instruments in  the  over-the-counter
market. There
    
 
                                       19
<PAGE>
   
currently  are limited securities  index futures and options  on such futures in
many countries, particularly  emerging countries. The  nature of the  strategies
adopted  by the Adviser, and the extent  to which those strategies are used, may
depend on the development of such markets.
    
 
   
    The  Portfolios  may  engage  in  transactions  involving  foreign  currency
exchange  futures contracts. Such contracts involve an obligation to purchase or
sell a specific currency at  a specified future date  and at a specified  price.
The  Portfolios  may  engage  in such  transactions  to  hedge  their respective
holdings and commitments against changes in  the level of future currency  rates
or to gain exposure to a particular currency.
    
 
   
    The   Portfolios  may  engage  in  transactions  in  interest  rate  futures
transactions. Interest rate futures contracts involve an obligation to  purchase
or  sell a specific debt  security, instrument or basket  thereof at a specified
future date at  a specified price.  The value  of the contract  rises and  falls
inversely  with changes  in interest  rates. The  Portfolios may  engage in such
transactions to hedge their holdings of debt instruments against future  changes
in interest rates.
    
 
   
    Financial  futures are futures contracts  relating to financial instruments,
such as  U.S. Government  securities, foreign  currencies, and  certificates  of
deposit.  Such contracts  involve an obligation  to purchase or  sell a specific
security, instrument or basket thereof at a specified future date at a specified
price. Like  interest rate  futures contracts,  the value  of financial  futures
contracts  rises  and  falls  inversely  with  changes  in  interest  rates. The
Portfolios may engage in financial futures contracts for hedging and non-hedging
purposes.
    
 
   
    Under rules  adopted  by  the Commodity  Futures  Trading  Commission,  each
Portfolio  may enter into futures contracts and options thereon for both hedging
and non-hedging purposes,  provided that not  more than 5%  of such  Portfolios'
total  assets at the time of entering the transaction are required as margin and
option  premiums  to  secure  obligations  under  such  contracts  relating   to
activities  that do not constitute "bona  fide" hedging. No Portfolio will enter
into futures  contracts  to  the  extent that  its  outstanding  obligations  to
purchase  securities under such  contracts, in combination  with its outstanding
obligations with respect to options transactions (including options to  purchase
securities or instruments) would exceed 20% of its total assets.
    
 
   
    Gains  and losses  on futures  contracts and  options thereon  depend on the
Adviser's ability  to  predict correctly  the  direction of  securities  prices,
interest  rates and other economic factors.  Other risks associated with the use
of futures  and options  are (i)  imperfect correlation  between the  change  in
market  value of investments held  by a Portfolio and  the prices of futures and
options relating to  investments purchased or  sold by the  Portfolio, and  (ii)
possible  lack  of a  liquid secondary  market  for a  futures contract  and the
resulting inability to close a futures position. The risk that a Portfolio  will
be  unable to close out a futures position or options contract will be minimized
by only entering into futures contracts or options transactions for which  there
appears to be a liquid exchange or secondary market. The risk of loss in trading
on  futures contracts in some strategies can be substantial, due both to the low
margin deposits required and the extremely  high degree of leverage involved  in
futures pricing.
    
 
    LOANS  OF PORTFOLIO SECURITIES.  The Portfolios may lend their securities to
brokers, dealers, domestic and foreign banks or other financial institutions for
the purpose of increasing its net investment income. These loans must be secured
continuously by cash or equivalent collateral, or by a letter of credit at least
equal to the  market value  of the securities  loaned plus  accrued interest  or
income.  There may be a risk of delay in recovery of the securities or even loss
of rights  in  the  collateral  should  the  borrower  of  the  securities  fail
financially.  A  Portfolio  will  not enter  into  securities  loan transactions
exceeding, in the aggregate, 33 1/3% of the market value of its total assets.
 
                                       20
<PAGE>
   
    MONEY  MARKET INSTRUMENTS.   Each Portfolio is permitted  to invest in money
market  instruments,  although  the  Portfolios  intend  to  stay  invested   in
securities   satisfying  their  primary  investment   objective  to  the  extent
practical. Each  Portfolio  may  make money  market  investments  pending  other
investment  or settlement  for liquidity, or  in adverse  market conditions. See
"Temporary  Investments."  The  money  market  investments  permitted  for   the
Portfolios  include  obligations of  the U.S.  Government  and its  agencies and
instrumentalities; other debt  securities; commercial  paper; bank  obligations;
certificates  of  deposit (including  Eurodollar  certificates of  deposit); and
repurchase agreements.
    
 
    NON-PUBLICLY  TRADED   SECURITIES,   PRIVATE   PLACEMENTS   AND   RESTRICTED
SECURITIES.   The Equity  Growth and Aggressive Equity  Portfolios may invest in
securities  that   are  neither   listed  on   a  stock   exchange  nor   traded
over-the-counter. Such unlisted equity securities may involve a higher degree of
business  and financial risk that can result  in substantial losses. As a result
of the absence of a public trading market for these securities, they may be less
liquid than publicly traded securities. Although these securities may be  resold
in privately negotiated transactions, the prices realized from these sales could
be  less than those originally  paid by the Portfolios or  less than what may be
considered  the  fair  value  of  such  securities.  Further,  companies   whose
securities  are not  publicly traded  may not be  subject to  the disclosure and
other investor  protection  requirements  which might  be  applicable  if  their
securities  were  publicly  traded.  If  such  securities  are  required  to  be
registered under the securities laws of  one or more jurisdictions before  being
resold, the Portfolio may be required to bear the expenses of registration.
 
   
    As  a general matter,  a Portfolio may not  invest more than  15% of its net
assets in  illiquid  securities, including  securities  for which  there  is  no
readily available secondary market. Securities that are not registered under the
Securities  Act  of  1933, as  amended,  but that  can  be offered  and  sold to
qualified institutional  buyers  under Rule  144A  under that  Act  ("Rule  144A
Securities")  will not be  included within the foregoing  15% restriction if the
securities are  determined to  be liquid.  The Board  of Directors  has  adopted
guidelines and delegated to the Adviser, subject to the supervision of the Board
of  Directors, the daily function of determining and monitoring the liquidity of
Rule 144A  Securities. Rule  144A Securities  may become  illiquid if  qualified
institutional buyers are not interested in acquiring the securities.
    
 
   
    OPTIONS  TRANSACTIONS.  The  Equity Growth and  Aggressive Equity Portfolios
may seek to  increase their  returns or  may hedge  their portfolio  investments
through options transactions with respect to securities, instruments, indices or
baskets  thereof in which such Portfolios may invest, as well as with respect to
foreign currency. Purchasing a put option gives a Portfolio the right to sell  a
specified  security,  currency  or basket  of  securities or  currencies  at the
exercise price until  the expiration  of the  option. Purchasing  a call  option
gives a Portfolio the right to purchase a specified security, currency or basket
of  securities or currencies at  the exercise price until  the expiration of the
option. A Portfolio may not purchase call and put options to the extent that the
value of its aggregate investment in options exceeds 5% of its total assets.
    
 
   
    The Portfolios  also  may  write  (i.e.,  sell)  put  and  call  options  on
investments  held in its portfolio, as well as with respect to foreign currency.
A Portfolio that has written an  option receives a premium, which increases  the
Portfolio's  return on  the underlying security  or instrument in  the event the
option expires unexercised or is closed out  at a profit. However, by writing  a
call  option, a Portfolio will limit its  opportunity to profit from an increase
in the market value of the underlying security or instrument above the  exercise
price  of the option for as long as  the Portfolio's obligation as writer of the
option  continues.   The   Portfolios   may  only   write   options   that   are
    
 
                                       21
<PAGE>
   
"covered."  A  covered  call option  means  that  so long  as  the  Portfolio is
obligated as the writer of the option,  it will own (i) the underlying  security
or   instrument  subject  to  the  option  or  (ii)  securities  or  instruments
convertible or exchangeable without  the payment of  any consideration into  the
security or instrument subject to the option.
    
 
   
    By  writing (or selling) a  put option, a Portfolio  incurs an obligation to
buy the security or instrument underlying  the option from the purchaser of  the
put  at the option's exercise price at any time during the option period, at the
purchaser's election. Options written by a  Portfolio may be exercisable by  the
purchaser  only on a  specific date. A  Portfolio that has  written a put option
will earmark  or segregate  sufficient liquid  assets to  cover its  obligations
under the option.
    
 
   
    The  Portfolios may  engage in transactions  in options which  are traded on
recognized exchanges or  over-the-counter. There currently  are limited  options
markets  in  many  countries,  particularly  emerging  countries  such  as Latin
American countries, and the nature of the strategies adopted by the Adviser  and
the  extent to which those strategies are used will depend on the development of
such option markets. The  primary risks associated with  the use of options  are
(i)  imperfect correlation  between the  change in  market value  of investments
held, purchased or sold  by a Portfolio  and the prices  of options relating  to
such  investments; and (ii)  possible lack of  a liquid secondary  market for an
option.
    
 
    REPURCHASE AGREEMENTS.  The Portfolios may enter into repurchase  agreements
with  brokers, dealers or  banks that meet the  credit guidelines established by
the Fund's Board of Directors. In  a repurchase agreement, the Portfolio buys  a
security  from a seller  that has agreed  to repurchase it  at a mutually agreed
upon date and price, reflecting the interest rate effective for the term of  the
agreement.  The term of these agreements is  usually from overnight to one week,
and never  exceeds one  year. Repurchase  agreements may  be viewed  as a  fully
collateralized  loan  of money  by the  Portfolio to  the seller.  The Portfolio
always receives securities, with a market  value at least equal to the  purchase
price  (including accrued interest)  as collateral and  this value is maintained
during the term  of the  agreement. If the  seller defaults  and the  collateral
value  declines, the Portfolio might incur a loss. If bankruptcy proceedings are
commenced with  respect to  the  seller, the  Portfolio's realization  upon  the
collateral  may  be  delayed  or  limited. The  Portfolios  may  not  enter into
repurchase agreements with  more than seven  days to maturity  if, as a  result,
more  than 15% of the market value of the Portfolio's net assets are invested in
these agreements  and other  investments  for which  market quotations  are  not
readily available or which are otherwise illiquid.
 
    SHORT  SALES.  The  Aggressive Equity Portfolio  may from time  to time sell
securities short consistent with applicable legal requirements. A short sale  is
a  transaction in which the Portfolio sells securities it either owns or has the
right to acquire at no added cost (i.e., "against the box") or does not own (but
has borrowed)  in  anticipation  of  a  decline  in  the  market  price  of  the
securities.  To  deliver the  securities to  the  buyer, the  Portfolio arranges
through a broker to borrow the securities  and, in so doing, the Portfolio  will
become obligated to replace the securities borrowed at their market price at the
time  of the replacement, whatever that price may be. When the Portfolio makes a
short sale of borrowed securities, the  proceeds it receives from the sale  will
be  held  on  behalf of  a  broker  until the  Portfolio  replaces  the borrowed
securities. The Portfolio may have to pay a premium to borrow the securities and
must pay any  dividends or  interest payable on  the securities  until they  are
replaced.
 
    The  Portfolio's obligation to replace the securities borrowed in connection
with a short sale will be secured  by collateral deposited with the broker  that
consists  of  cash  or  other  liquid  securities.  In  addition,  if  the short
 
                                       22
<PAGE>
   
sale is not "against the box", the Portfolio will place in a segregated  account
with  the Custodian an  amount of cash  or other liquid  securities equal to the
difference, if any, between (1) the market  value of the securities sold at  the
time  they were sold short and (2) any cash or other liquid securities deposited
as collateral with the broker in connection with the short sale. Short sales  by
the Portfolios involve certain risks and special considerations. Possible losses
from  short sales differ from losses that could be incurred from a purchase of a
security, because losses from short sales may be unlimited, whereas losses  from
purchases can equal only the total amount invested.
    
 
    SMALL- AND MEDIUM-SIZED COMPANIES.  Because the Emerging Growth and MicroCap
Portfolios  seek long-term capital appreciation by investing primarily in small-
to medium-sized companies and small companies, respectively, both of which types
of companies are more vulnerable to financial and other risks than larger,  more
established  companies,  investments in  these Portfolios  may involve  a higher
degree of  risk  and price  volatility  than  the general  equity  markets.  The
Aggressive  Equity Portfolio may invest in small- to medium-sized companies to a
lesser extent.
 
    TEMPORARY INVESTMENTS.  During periods in which the Adviser believes changes
in economic, financial or political conditions make it advisable, the Portfolios
may reduce their holdings in equity and other securities for temporary defensive
purposes and the Portfolios may invest  in certain short-term (less than  twelve
months  to maturity) and  medium-term (not greater than  five years to maturity)
debt securities or may hold cash. The short-term and medium-term debt securities
in which  the Portfolio  may invest  consist of  (a) obligations  of the  United
States   or   foreign  country   governments,   their  respective   agencies  or
instrumentalities;  (b)   bank   deposits  and   bank   obligations   (including
certificates  of  deposit, time  deposits  and bankers'  acceptances)  of United
States or foreign country banks denominated  in any currency; (c) floating  rate
securities   and  other  instruments  denominated  in  any  currency  issued  by
international development agencies; (d) finance company and corporate commercial
paper and  other short-term  corporate  debt obligations  of United  States  and
foreign  country corporations meeting the  Portfolio's credit quality standards;
and (e) repurchase agreements with banks and broker-dealers with respect to such
securities. For temporary  defensive purposes, the  Portfolios intend to  invest
only  in short-term and medium-term debt securities that the Adviser believes to
be of high quality, i.e., subject to relatively low risk of loss of interest  or
principal  (there  is currently  no rating  system for  debt securities  to most
foreign countries).
 
    WHEN-ISSUED AND DELAYED  DELIVERY SECURITIES.   The Portfolios may  purchase
securities  on a  when-issued or delayed  delivery basis.  In such transactions,
instruments are bought with payment and  delivery taking place in the future  in
order  to secure what is considered to be  an advantageous yield or price at the
time of the transaction. Delivery of  and payment for these securities may  take
as  long as a month or more after  the date of the purchase commitment, but will
take place  no more  than 120  days after  the trade  date. The  Portfolio  will
maintain  with the Custodian  a separate account with  a segregated portfolio of
cash or liquid securities in an amount at least equal to these commitments.  The
payment  obligation and the interest rates that  will be received are each fixed
at the time a Portfolio  enters into the commitment  and no interest accrues  to
the  Portfolio until settlement. Thus,  it is possible that  the market value at
the time of settlement could be higher  or lower than the purchase price if  the
general  level of  interest rates  has changed.  It is  a current  policy of the
Portfolios not to enter into when-issued commitments exceeding in the  aggregate
15%  of the Portfolio's net  assets other than the  obligations created by these
commitments.
 
                                       23
<PAGE>
                             INVESTMENT LIMITATIONS
 
    Each of the Equity  Growth and Emerging Growth  Portfolios is a  diversified
investment  company  and  is  therefore  subject  to  the  following fundamental
limitations: (a) as to 75% of its total assets, a Portfolio may not invest  more
than  5%  of  its total  assets  in the  securities  of any  one  issuer, except
obligations of the U.S. Government  and its agencies and instrumentalities,  and
(b)  a Portfolio may not own more  than 10% of the outstanding voting securities
of any one issuer.
 
   
    The MicroCap and Aggressive Equity Portfolios are non-diversified portfolios
under the 1940 Act, which means that the Portfolios are not limited by the  1940
Act in the proportion of their assets that may be invested in the obligations of
a  single issuer. Thus, the Portfolios may  invest a greater proportion of their
assets in the securities of  a small number of issuers  and as a result will  be
subject   to  greater   risk  with   respect  to   their  portfolio  securities.
Nevertheless, the Portfolios intend to comply with more limited  diversification
requirements  imposed  by the  Internal Revenue  Code of  1986, as  amended (the
"Code"), for qualification as regulated investment companies.
    
 
    Each Portfolio also operates under certain investment restrictions that  are
deemed  fundamental limitations and may be changed only with the approval of the
holders of a majority of such  Portfolio's outstanding shares and under  certain
non-fundamental  investment limitations that may  be changed without shareholder
approval.  For  additional  information   on  fundamental  and   non-fundamental
investment  limitations,  see  "Investment  Limitations"  in  the  Statement  of
Additional Information.
 
                             MANAGEMENT OF THE FUND
 
    INVESTMENT ADVISER.  Morgan Stanley Asset Management Inc. is the Adviser and
Administrator of the Fund  and each Portfolio.  The Adviser provides  investment
advice  and portfolio  management services,  pursuant to  an Investment Advisory
Agreement and, subject  to the  supervision of  the Fund's  Board of  Directors,
makes  each of the Portfolio's day-to-day investment decisions, arranges for the
execution  of  portfolio  transactions  and   generally  manages  each  of   the
Portfolio's  investments. Set  forth below  as an  annual percentage  of average
daily net assets  are the management  fees payable to  the Adviser quarterly  by
each  Portfolio pursuant to the terms  of the Investment Advisory Agreement. The
fees for  the Emerging  Growth, MicroCap  and Aggressive  Equity Portfolios  are
higher  than most  investment companies  because each  of the  Portfolios invest
internationally. The Adviser believes that the  fees are comparable to those  of
other  investment companies that invest  internationally. The Adviser has agreed
to a reduction in  the fees payable  to it and to  reimburse the Portfolios,  if
necessary,  if such fees would cause the  total annual operating expenses of the
Portfolios to exceed the maximums set forth below.
 
   
<TABLE>
<CAPTION>
                                                                  MAXIMUM TOTAL OPERATING
                                                                     EXPENSES AFTER FEE
                                                                           WAIVER
                                                                  ------------------------
                  PORTFOLIO                     MANAGEMENT FEE      CLASS A      CLASS B
- ---------------------------------------------  -----------------  -----------  -----------
<S>                                            <C>                <C>          <C>
Equity Growth Portfolio                                0.60%           0.80%        1.05%
Emerging Growth Portfolio                              1.00%           1.25%        1.50%
MicroCap Portfolio                                     1.25%           1.50%        1.75%
Aggressive Equity Portfolio                            0.80%           1.00%        1.25%
</TABLE>
    
 
                                       24
<PAGE>
   
    The Adviser, with  principal offices  at 1221  Avenue of  the Americas,  New
York,  New York  10020, conducts a  worldwide portfolio  management business and
provides a broad  range of  portfolio management  services to  customers in  the
United  States and abroad.  On February 5,  1997, Morgan Stanley  Group Inc. and
Dean Witter, Discover &  Co. announced that they  had entered into an  Agreement
and  Plan of Merger to  form Morgan Stanley, Dean  Witter, Discover & Co. Morgan
Stanley Group  Inc. is  the direct  parent of  the Adviser  and Morgan  Stanley.
Subject  to certain conditions  being met, it is  currently anticipated that the
transaction will close in mid-1997.  Thereafter, the Adviser and Morgan  Stanley
will be subsidiaries of Morgan Stanley, Dean Witter, Discover & Co. At March 31,
1997,  the  Adviser, together  with its  affiliated asset  management companies,
managed investments totaling in excess of $118 billion, including  approximately
$100  billion  under active  management and  $18 billion  as Named  Fiduciary or
Fiduciary Adviser. See "Management of the  Fund" in the Statement of  Additional
Information.
    
 
    PORTFOLIO  MANAGERS.  The following  persons have primary responsibility for
managing the Portfolios indicated.
 
   
    EQUITY GROWTH PORTFOLIO  -- KURT  FEUERMAN AND  MARGARET K.  JOHNSON.   Kurt
Feuerman  joined  Morgan Stanley  Asset Management  in July  1993 as  a Managing
Director in  the  Institutional Equity  Group.  Previously Mr.  Feuerman  was  a
Managing  Director of Morgan Stanley  & Co., Incorporated's Research Department,
where he was  responsible for  emerging growth stocks,  gaming and  restaurants.
Before  joining Morgan Stanley,  Mr. Feuerman was a  Managing Director of Drexel
Burnham Lambert, where he had been an equity analyst since 1984. Over the years,
he has been highly  ranked in the Institutional  Investor All American  Research
Poll  in four separate  categories: packaged food,  tobacco, emerging growth and
gaming. Mr. Feuerman earned an M.B.A. from Columbia University in 1982, an  M.A.
from  Syracuse University in  1980, and a  B.A. from McGill  University in 1977.
Margaret Johnson is a Principal  of the Adviser and  a Portfolio Manager in  the
Institutional  Equity Group.  She joined  the Adviser in  1984 and  worked as an
Analyst in the  Marketing and  Fiduciary Advisor  areas. Ms.  Johnson became  an
Equity  Analyst in 1986 and a Portfolio Manager in 1989. Prior to joining Morgan
Stanley, she worked for the New York  City PBS affiliate, WNET, Channel 13.  She
holds  a B.A. degree from Yale College and is a Chartered Financial Analyst. Mr.
Feuerman and  Ms.  Johnson have  had  primary responsibility  for  managing  the
Portfolio's assets since July 1993 and April 1991, respectively.
    
 
   
    EMERGING  GROWTH  PORTFOLIO  --  KURT A.  FEUERMAN,  DANIEL  R.  LASCANO AND
CHRISTOPHER R. BLAIR.   Information  about Mr.  Feuerman is  included under  the
Equity Growth Portfolio above.
    
 
   
    Daniel  Lascano is a  Vice President of Morgan  Stanley Asset Management. He
joined the Firm in 1993 as an equity analyst. Prior to joining the Adviser,  Mr.
Lascano worked at Morgan Stanley & Co. as a research assistant to Kurt Feuerman.
Mr.  Lascano graduated from the University of California at Berkeley with a B.A.
in Economics and Statistics.
    
 
   
    Christopher Blair  joined  Morgan Stanley  Asset  Management in  1993  as  a
Security  Analyst  in  the Emerging  Growth  Stock  Group. He  was  elected Vice
President in 1996. Prior to joining the Adviser, he was a Financial Analyst  for
two  years in Morgan Stanley's Corporate Finance Department, where he focused on
the  telecommunications  and  technology  sectors.  Mr.  Blair  graduated   with
Distinction  from  McGill  University with  a  B.A. in  Economics  and Political
Science.  Mr.  Feuerman,  Mr.  Lascano   and  Mr.  Blair  have  shared   primary
responsibility for managing the Portfolio's assets since April 1997.
    
 
                                       25
<PAGE>
    MICROCAP  PORTFOLIO --  DENNIS G. SHERVA.   Information about  Mr. Sherva is
included under the Emerging Growth Portfolio above.
 
    AGGRESSIVE EQUITY  PORTFOLIO  --  KURT  FEUERMAN.    Information  about  Mr.
Feuerman is included under the Equity Growth Portfolio above.
 
    ADMINISTRATOR.   The  Adviser also  provides administrative  services to the
Fund pursuant to an  Administration Agreement. The  services provided under  the
Administration  Agreement are subject to the supervision of the Officers and the
Board of Directors of the Fund and include day-to-day administration of  matters
related  to the  corporate existence  of the  Fund, maintenance  of its records,
preparation  of  reports,  supervision  of  the  Fund's  arrangements  with  its
custodian,  and  assistance  in  the  preparation  of  the  Fund's  registration
statements under federal laws. The  Administration Agreement also provides  that
the Administrator, through its agents, will provide the Fund dividend disbursing
and   transfer  agent  services  to  the   Fund.  For  its  services  under  the
Administration Agreement, the Fund  pays the Adviser a  monthly fee which on  an
annual basis equals 0.15% of the average daily net assets of each Portfolio.
 
   
    Under  an  agreement  between  the  Adviser  and  The  Chase  Manhattan Bank
("Chase"), Chase provides  certain administrative services  to the Fund  through
its  corporate  affiliate, Chase  Global Funds  Services Company  ("CGFSC"). The
Adviser supervises and monitors such administrative services provided by  CGFSC.
Their  services are also subject to the supervision of the Board of Directors of
the Fund. CGFSC's business address  is 73 Tremont Street, Boston,  Massachusetts
02108-3913.
    
 
    DIRECTORS  AND OFFICERS.  Pursuant to  the Fund's Articles of Incorporation,
the Board of Directors  decides upon matters of  general policy and reviews  the
actions  of  the Fund's  Adviser, Administrator,  Distributor and  other service
providers. The Officers  of the Fund  conduct and supervise  its daily  business
operations.
 
    DISTRIBUTOR.   Morgan  Stanley serves  as the  exclusive Distributor  of the
shares of  the Fund.  Under its  Distribution Agreement  with the  Fund,  Morgan
Stanley  sells  shares of  each  Portfolio upon  the  terms and  at  the current
offering price described in this Prospectus. Morgan Stanley is not obligated  to
sell any certain number of shares of any Portfolio.
 
    The  Portfolios currently offer  only the classes of  shares offered by this
Prospectus. The Portfolios may in the future offer one or more classes of shares
with features, distribution expenses or  other expenses that are different  from
those of the classes currently offered.
 
    The  Fund has  adopted a Plan  of Distribution  with respect to  the Class B
shares of each  Portfolio pursuant to  Rule 12b-1  under the 1940  Act (each,  a
"Plan").  Under  each Plan,  the Distributor  is entitled  to receive  from each
Portfolio a distribution  fee, which  is accrued  daily and  paid quarterly,  of
0.25%  of the Class B  shares' average daily net  assets on an annualized basis.
The Distributor  expects  to  reallocate  most of  its  fee  to  its  investment
representatives.  The Distributor may, in its discretion, voluntarily waive from
time to  time all  or  any portion  of  its distribution  fee  and each  of  the
Distributor  and the Adviser if free to  make additional payments out of its own
assets to promote the  sale of Fund shares,  including payments that  compensate
financial institutions for distribution services or shareholder services.
 
    The  Plan is designed to compensate the Distributor for its services, not to
reimburse the Distributor for its expenses,  and the Distributor may retain  any
portion  of the fee that it does not expend in fulfillment of its obligations to
the Fund.
 
                                       26
<PAGE>
    EXPENSES.  Each Portfolio is responsible  for payment of certain other  fees
and  expenses  (including legal  fees,  accountants' fees,  custodial  fees, and
printing and mailing  costs) specified  in the  Administration and  Distribution
Agreements.
 
                               PURCHASE OF SHARES
 
    Class  A and Class  B shares of each  Portfolio may be  purchased at the net
asset value per share next determined after receipt of the purchase order by the
Portfolio. See "Valuation of Shares."
 
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
 
    For a  Portfolio  account  opened  on  or after  January  2,  1996  (a  "New
Account"),  the minimum initial investment and minimum account size are $500,000
for Class A shares and  $100,000 for Class B  shares of each Portfolio.  Certain
advisory  or asset allocation accounts, such as Total Funds Management accounts,
managed by Morgan  Stanley or  its affiliates, including  the Adviser  ("Managed
Accounts")  may purchase  Class A shares  without being subject  to such minimum
initial investment or minimum account size requirements for a Portfolio account.
Employees of the  Adviser and  certain of its  affiliates may  purchase Class  A
Shares  subject  to conditions,  including a  lower minimum  initial investment,
established by Officers of the Fund.
 
    If the value of a New Account containing Class A shares falls below $500,000
(but remains at  or above  $100,000) because of  shareholder redemption(s),  the
Fund  will  notify  the shareholder,  and  if  the account  value  remains below
$500,000 (but remains at or above $100,000) for a continuous 60-day period,  the
Class  A shares  in such  account will  convert to  Class B  shares and  will be
subject to the  distribution fee and  other features applicable  to the Class  B
shares.  The Fund, however,  will not convert  Class A shares  to Class B shares
based solely upon  changes in  the market  that reduce  the net  asset value  of
shares.  Under  current tax  law, conversions  between share  classes are  not a
taxable event to the shareholder.
    Shares in a Portfolio account opened  prior to January 2, 1996 (a  "Pre-1996
Account")  were  designated Class  A  shares on  January  2, 1996.  Shares  in a
Pre-1996 Account  with  a  value  of  $100,000 or  more  on  March  1,  1996  (a
"Grandfathered  Class A Account") remained Class  A shares regardless of account
size thereafter. Except for  shares in a Managed  Account, shares in a  Pre-1996
Account  with a value of  less than $100,000 on  March 1, 1996 (a "Grandfathered
Class B Account") converted  to Class B shares  on March 1, 1996.  Grandfathered
Class A Accounts and Managed Accounts are not subject to conversion from Class A
shares to Class B shares.
 
    Investors  may also invest in the Fund  by purchasing shares through a trust
department, broker, dealer, agent, financial planner, financial services firm or
investment adviser.  An  investor  may  be  charged  an  additional  service  or
transaction fee by that institution.
 
   
    The minimum investment levels may be waived at the discretion of the Adviser
for  (i) certain employees and customers of Morgan Stanley or its affiliates and
certain  trust  departments,  brokers,  dealers,  agents,  financial   planners,
financial  services  firms, or  investment advisers  that  have entered  into an
agreement with  Morgan  Stanley  or  its affiliates;  and  (ii)  retirement  and
deferred  compensation plans and trusts used  to fund such plans, including, but
not limited to, those defined in Section  401(a), 403(b) or 457 of the Code  and
"rabbi  trusts."  The  Fund  reserves  the  right  to  modify  or  terminate the
conversion features  of the  shares as  stated above  at any  time upon  60-days
notice to shareholders.
    
 
                                       27
<PAGE>
    The  Adviser reserves the right in its sole discretion to determine which of
such advisory  or  asset allocation  accounts  shall be  Managed  Accounts.  For
information  regarding  Managed  Accounts, please  contact  your  Morgan Stanley
account representative or the Fund at the telephone number provided on the cover
of this Prospectus.
 
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
 
    If the value of  a New Account falls  below $100,000 because of  shareholder
redemption(s),  the Fund will  notify the shareholder, and  if the account value
remains below  $100,000 for  a  continuous 60-day  period,  the shares  in  such
account  are subject to redemption  by the Fund and,  if redeemed, the net asset
value of  such  shares will  be  promptly paid  to  the shareholder.  The  Fund,
however,  will not redeem  shares based solely  upon changes in  the market that
reduce the net asset value of shares.
 
    Grandfathered Class A Accounts, Grandfathered  Class B Accounts and  Managed
Accounts  are not subject to involuntary redemption. The Fund reserves the right
to modify or  terminate the  involuntary redemption  features of  the shares  as
stated above at any time upon 60-days notice to shareholders.
 
CONVERSION FROM CLASS B TO CLASS A SHARES
 
    If the value of Class B shares in a Portfolio account increases, whether due
to  shareholder share  purchases or  market activity,  to $500,000  or more, the
Class B shares  will convert  to Class  A shares.  Under current  tax law,  such
conversion  is not a taxable event to  the shareholder. Class A shares converted
from Class B shares  are subject to the  same minimum account size  requirements
that  are applicable to New Accounts containing Class A shares, as stated above.
The Fund reserves the  right to modify or  terminate this conversion feature  at
any time upon 60-days notice to shareholders.
 
INITIAL PURCHASES DIRECTLY FROM THE FUND
 
    The  Fund's determination of an investor's eligibility to purchase shares of
a given class  will take precedence  over the investor's  selection of a  class.
Assuming  the investor is eligible for the  class, the Fund will select the most
favorable class for the investor, if the investor has not done so.
 
1) BY CHECK.   An account may  be opened  by completing and  signing an  Account
   Registration Form and mailing it, together with a check ($500,000 minimum for
   Class  A shares  of each Portfolio  and $100,000  for Class B  shares of each
   Portfolio, with certain  exceptions for Morgan  Stanley employees and  select
   customers)  payable to "Morgan Stanley Institutional Fund, Inc. -- [portfolio
   name]", to:
 
      Morgan Stanley Institutional Fund, Inc.
     P.O. Box 2798
     Boston, Massachusetts 02208-2798
 
    Payment will  be accepted only  in U.S. dollars,  unless prior approval  for
  payment by other currencies is given by the Fund. The classes of shares of the
  Portfolio(s)  to be purchased should be designated on the Account Registration
  Form. For purchases  by check, the  Fund is ordinarily  credited with  Federal
  Funds  within one  business day.  Thus, your  purchase of  shares by  check is
  ordinarily credited to your account at the  net asset value per share of  each
  of the relevant Portfolios determined on the next business day after receipt.
 
                                       28
<PAGE>
2) BY  FEDERAL  FUNDS WIRE.   Purchases  may be  made by  having your  bank wire
   Federal Funds to the Fund's bank  account. In order to ensure prompt  receipt
   of your Federal Funds Wire, it is important that you follow these steps:
 
A.   Telephone  the Fund  (toll free: 1-800-548-7786)  and provide  us with your
    name, address,  telephone  number,  Social Security  or  Tax  Identification
    Number,  the  portfolio(s) selected,  the class  selected, the  amount being
    wired, and by  which bank.  We will  then provide  you with  a Fund  account
    number.  (Investors with existing accounts should also notify the Fund prior
    to wiring funds.)
 
B.   Instruct  your  bank to  wire  the  specified amount  to  the  Fund's  Wire
    Concentration  Bank Account (be sure  to have your bank  include the name of
    the portfolio(s)  selected,  the  class  selected  and  the  account  number
    assigned to you) as follows:
 
   
    The Chase Manhattan Bank
    One Manhattan Plaza
    New York, NY 10081-1000
    ABA #021000021
    DDA #910-2-733293
    Attn: Morgan Stanley Institutional Fund, Inc.
    Ref: (Portfolio name, your account number, your account name)
    
 
    Please call the Fund at 1-800-548-7786 prior to wiring funds.
 
C.   Complete  the Account Registration  Form and  mail it to  the address shown
    thereon.
 
  The purchase price of the Class A and Class B shares of each Portfolio is  the
  net asset value next determined after the order is received. See "Valuation of
  Shares."  An order received prior to the  close of the New York Stock Exchange
  ("NYSE"), which is currently 4:00 p.m.  Eastern Time, will be executed at  the
  price  computed on the date  of receipt; an order  received after the close of
  the NYSE will be executed  at the price computed on  the next day the NYSE  is
  open  as long as  the Transfer Agent  receives payment by  check or in Federal
  Funds prior to the regular close of the NYSE on such day.
 
  Federal Funds purchase orders will be accepted only on a day on which the Fund
  and Chase (the "Custodian Bank") are open for business. Your bank may charge a
  service fee for wiring Federal Funds.
 
3) BY BANK WIRE.   The  same procedure outlined  under "By  Federal Funds  Wire"
   above  must be  followed in  purchasing shares  by bank  wire. However, money
   transferred by bank wire may or may  not be converted into Federal Funds  the
   same  day, depending on the time the  money is received and the bank handling
   the wire. Prior to such conversion, an investor's money will not be invested.
   Your bank may charge a service fee for wiring funds.
 
                                       29
<PAGE>
ADDITIONAL INVESTMENTS
 
    You  may  add to  your account  at any  time (minimum  additional investment
$1,000 for each portfolio,  except for automatic  reinvestment of dividends  and
capital  gains  distributions for  which there  are  no minimums)  by purchasing
shares at net asset  value by mailing  a check to the  Fund (payable to  "Morgan
Stanley  Institutional Fund, Inc. -- [portfolio  name]") at the above address or
by wiring monies to the Custodian Bank  as outlined above. It is very  important
that  your account name, the portfolio name  and the class selected be specified
in the letter or wire  to assure proper crediting to  your account. In order  to
ensure  that your wire orders are invested promptly, you are requested to notify
one of the Fund's representatives (toll free: 1-800-548-7786) prior to the  wire
date.  Additional investments will  be applied to  purchase additional shares in
the same class held by a shareholder in a Portfolio account.
 
OTHER PURCHASE INFORMATION
 
    Although the legal rights of Class A  and Class B shares will be  identical,
the  different expenses borne by  each class will result  in different net asset
values and dividends. The net  asset value of Class  B shares will generally  be
lower than the net asset value of Class A shares as a result of the distribution
expense  charged to Class B shares. It  is expected, however, that the net asset
value per share of the two classes  will tend to converge immediately after  the
recording  of dividends  which will  differ by  approximately the  amount of the
distribution expense accrual differential between the classes.
 
    In the interest  of economy and  convenience, and because  of the  operating
procedures  of the  Fund, certificates  representing shares  of the Portfolio(s)
will not be issued. All  shares purchased are confirmed  to you and credited  to
your  account on the Fund's  books maintained by the  Adviser or its agents. You
will have  the same  rights and  ownership with  respect to  such shares  as  if
certificates had been issued.
 
    To  ensure that checks are collected by the Fund, withdrawals of investments
made by check  are not presently  permitted until payment  for the purchase  has
been  received,  which may  take up  to eight  business days  after the  date of
purchase. As a condition  of this offering,  if a purchase  is cancelled due  to
nonpayment or because your check does not clear, you will be responsible for any
loss  the Fund or its  agents incur. If you are  already a shareholder, the Fund
may redeem shares from your account(s) to  reimburse the Fund or its agents  for
any  loss. In addition, you  may be prohibited or  restricted from making future
investments in the Fund.
 
    Investors may  also invest  in the  Fund by  purchasing shares  through  the
Distributor.
 
EXCESSIVE TRADING
 
    Frequent   trades  involving  either  substantial   portfolio  assets  or  a
substantial portion of your  account or accounts controlled  by you can  disrupt
management  of a Portfolio and raise its expenses. Consequently, in the interest
of all the stockholders  of the Portfolio and  the Portfolios' performance,  the
Fund  may in its discretion bar a  stockholder that engages in excessive trading
of shares of a  Portfolio from further  purchases of shares of  the Fund for  an
indefinite  period. The  Fund considers  excessive trading  to be  more than one
purchase and sale  involving shares  of the  same Portfolio  within any  120-day
period.  As an example, exchanging  shares of Portfolios of  the Fund as follows
amounts to excessive  trading, exchanging shares  of Portfolio A  for shares  of
Portfolio  B, then exchanging shares of Portfolio B for shares of Portfolio C of
the Fund and again exchanging the shares of Portfolio C for shares of  Portfolio
B  within a  120-day period.  Two types  of transactions  are exempt  from these
 
                                       30
<PAGE>
   
excessive trading  restrictions: (1)  trades  exclusively between  money  market
portfolios,  and (2) trades done in  connection with an asset allocation service
such as TFM Accounts or accounts managed or advised by the Adviser and/or any of
its affiliates.
    
 
INVESTMENT IN FUNDS THROUGH A TOTAL FUNDS MANAGEMENT ("TFM") ACCOUNT
 
   
    In addition to the considerable diversification among individual  securities
you  receive by investing in a particular Portfolio, you can further reduce risk
by spreading  your assets  among  several different  Portfolios that  each  have
different   risk  and  return  characteristics.  TFM  is  an  active  investment
management service managed by Morgan Stanley or its affiliates, including Morgan
Stanley Asset  Management Inc.  (each,  a "TFM  Adviser"), that  allocates  your
investments  across a combination of either Class A or Class B shares of certain
of the Portfolios selected to meet your long-term investment objectives as  well
as, in certain circumstances, your current income objectives.
    
 
   
    The TFM Adviser has developed investment strategies for TFM Accounts to meet
the  diverse financial needs of different investors.  You can open a TFM Account
by meeting with one  of the investment professionals  of a Participating  Dealer
who  will review your situation and  help you identify your long-term investment
and/or current income  objectives. After  using TFM criteria  to determine  your
long-term  investment and/or  current income objectives,  you can  choose one of
several TFM investment strategies. Based  on your chosen strategy, your  initial
investment  will be allocated among a number of the Class A or Class B shares of
the Portfolios. Depending  on market  conditions, the  TFM Adviser  periodically
reallocates  the combination of Portfolios or the percentage amounts invested in
the shares  of each  Portfolio to  implement your  TFM investment  strategy.  In
addition,  your TFM Account will be periodically rebalanced to maintain your TFM
strategy's current asset allocation mix, if  and when the performance of one  or
more  of the  Portfolios unbalances  the strategy's  mix. You  will pay  the TFM
Adviser a fee for the  TFM Account service that is  in addition to and  separate
from the fees and expenses you will pay directly or indirectly as an investor in
the Portfolios. See "Fund Expenses."
    
 
   
    From  time to time, one or more of the Portfolios used for investment by the
TFM Accounts may experience relatively  large investments or redemptions due  to
the  TFM Account  allocations or  rebalancings recommended  by the  TFM Adviser.
These transactions will affect the Portfolios, since Portfolios that  experience
redemptions  as  a result  of  reallocations or  rebalancings  may have  to sell
portfolio securities and Portfolios  that receive additional  cash will have  to
invest  it in additional portfolio securities. While it is impossible to predict
the overall  impact of  these transactions  over time,  there could  be  adverse
effects on portfolio management to the extent that Portfolios may be required to
sell  securities or invest  cash at times  when they would  not otherwise do so.
These transactions  could also  have  tax consequences  if sales  of  securities
resulted  in  gains  and could  also  increase transaction  costs.  The Adviser,
representing the interests  of the  Portfolios, is committed  to minimizing  the
impact of TFM Account transactions on the Portfolios. The Adviser, however, will
have  a conflict in fulfilling  this responsibility in that  it also serves as a
TFM Adviser. In that  capacity, the Adviser, representing  the interests of  the
TFM  Accounts,  also  is  committed  to minimizing  the  impact  of  TFM Account
transactions on  the  Portfolios to  the  extent consistent  with  pursuing  the
investment  objectives of the TFM Accounts. In addition, an affiliate of the TFM
Adviser, the Distributor is compensated on the sale, and may be compensated  for
distribution  or shareholder services  on the sale of  shares of the Portfolios.
See "Purchase of Shares"  and "Shareholder Services  -- Exchange Features."  The
Adviser will monitor the impact of TFM Account transactions on the Portfolios.
    
 
                                       31
<PAGE>
                              REDEMPTION OF SHARES
 
    You  may  withdraw all  or  any portion  of the  amount  in your  account by
redeeming shares at any time. Please note  that purchases made by check are  not
permitted to be redeemed until payment of the purchase price has been collected,
which  may take up to  eight business days after  purchase. The Fund will redeem
Class A shares or Class B shares of a Portfolio at the next determined net asset
value of shares  of the applicable  class. On days  that both the  NYSE and  the
Custodian  Bank are open for business, the net  asset value per share of each of
the Portfolios  is  determined at  the  regular close  of  trading of  the  NYSE
(currently  4:00 p.m. Eastern Time). Shares of each Portfolio may be redeemed by
mail or telephone. No charge is made for redemption. Any redemption proceeds may
be more or less than the purchase price of your shares depending on, among other
factors, the market value of the investment securities held by the Portfolios.
 
BY MAIL
 
    Each Portfolio will redeem its Class A  shares or Class B shares at the  net
asset  value determined on the  date the request is  received, if the request is
received in "good  order" before  the regular close  of the  NYSE. Your  request
should  be addressed to Morgan Stanley  Institutional Fund, Inc., P.O. Box 2798,
Boston, Massachusetts 02208-2798,  except that deliveries  by overnight  courier
should be addressed to Morgan Stanley Institutional Fund, Inc., c/o Chase Global
Funds Services Company, 73 Tremont Street, Boston, Massachusetts 02108-3913.
 
    "Good  order"  means that  the  request to  redeem  shares must  include the
following documentation:
 
        (a)  A letter of instruction or a stock assignment specifying the  class
    and  number  of  shares or  dollar  amount  to be  redeemed,  signed  by all
    registered owners  of  the shares  in  the exact  names  in which  they  are
    registered;
 
        (b)   Any  required   signature  guarantees   (see  "Further  Redemption
    Information" below); and
 
        (c)   Other supporting  legal documents,  if required,  in the  case  of
    estates,  trusts, guardianships,  custodianships, corporations,  pension and
    profit sharing plans and other organizations.
 
    Shareholders who are uncertain of requirements for redemption should consult
with a Fund representative.
 
BY TELEPHONE
 
    Provided you have previously elected the Telephone Redemption Option on  the
Account  Registration  Form, you  can  request a  redemption  of your  shares by
calling the Fund  and requesting  the redemption proceeds  be mailed  to you  or
wired to your bank. Please contact one of the Fund's representatives for further
details.  In times of drastic market conditions, the telephone redemption option
may be  difficult  to  implement.  If you  experience  difficulty  in  making  a
telephone  redemption, your request may be made  by regular mail or express mail
and it will be implemented  at the net asset value  next determined after it  is
received.  Redemption requests  sent to  the Fund  through express  mail must be
mailed to the address of the Dividend Disbursing and Transfer Agent listed under
"General Information." The  Fund and  the Fund's transfer  agent (the  "Transfer
Agent")  will  employ reasonable  procedures  to confirm  that  the instructions
communicated by telephone  are genuine. These  procedures include requiring  the
investor  to provide certain personal identification  information at the time an
account  is  opened  and  prior  to  effecting  each  transaction  requested  by
telephone.  In addition, all telephone transaction requests will be recorded and
investors  may   be   required   to  provide   additional   telecopied   written
 
                                       32
<PAGE>
instructions  regarding transaction requests. Neither  the Fund nor the Transfer
Agent will be responsible for any loss, liability, cost or expense for following
instructions received by telephone that either of them reasonably believes to be
genuine.
 
    To change the commercial  bank or account  designated to receive  redemption
proceeds,  a written  request must  be sent  to the  Fund at  the address above.
Requests to change the bank  or account must be  signed by each shareholder  and
each signature must be guaranteed.
 
FURTHER REDEMPTION INFORMATION
 
    Normally  the  Fund will  make payment  for all  shares redeemed  within one
business day of receipt  of the request,  but in no event  will payment be  made
more  than  seven days  after receipt  of  a redemption  request in  good order.
However, payments to investors  redeeming shares which  were purchased by  check
will  not be made until  payment for the purchase  has been collected, which may
take up to eight days after the date of purchase. The Fund may suspend the right
of redemption or postpone the date upon which redemptions are effected at  times
when  the NYSE is closed, or under  any emergency circumstances as determined by
the Securities and Exchange Commission (the "Commission").
 
    If the Board  of Directors determines  that it would  be detrimental to  the
best  interests of  the remaining  shareholders of  a Portfolio  to make payment
wholly or partly in cash, the Fund  may pay the redemption proceeds in whole  or
in part by a distribution in-kind of securities held by the Portfolio in lieu of
cash    in    conformity   with    applicable    rules   of    the   Commission.
Distributions-in-kind will be made  in readily marketable securities.  Investors
may  incur brokerage charges on the sale  of portfolio securities so received in
payment of redemptions.
 
    To protect  your account,  the Fund  and its  agents from  fraud,  signature
guarantees  are required for  certain redemptions to verify  the identity of the
person who has  authorized a redemption  from your account.  Please contact  the
Fund  for further  information. See "Redemption  of Shares" in  the Statement of
Additional Information.
 
                              SHAREHOLDER SERVICES
 
EXCHANGE FEATURES
 
    You may exchange shares  that you own  in the Portfolios  for shares of  any
other  available portfolio(s) of  the Fund (other  than the International Equity
Portfolio, which is  closed to  new investors). In  exchanging for  shares of  a
portfolio  with more  than one  class, the  class of  shares you  receive in the
exchange will be determined in the same  manner as any other purchase of  shares
and  will not  be based  on the  class of  shares surrendered  for the exchange.
Consequently, the same minimum initial  investment and minimum account size  for
determining  the  class  of shares  received  in  the exchange  will  apply. See
"Purchase of  Shares." Shares  of the  portfolios may  be exchanged  by mail  or
telephone.  The privilege to exchange shares  by telephone is automatic and made
available without shareholder election. Before you make an exchange, you  should
read  the prospectus of the portfolio(s) in which you seek to invest. Because an
exchange transaction  is treated  as a  redemption followed  by a  purchase,  an
exchange  would be considered  a taxable event for  shareholders subject to tax.
The exchange privilege may  be modified or  terminated by the  Fund at any  time
upon 60-days notice to shareholders.
 
                                       33
<PAGE>
BY MAIL
 
    In  order to  exchange shares  by mail, you  should include  in the exchange
request the name, class of shares and account number of your current  Portfolio,
the  name(s) of  the portfolio(s)  and the  class(es) of  shares into  which you
intend to exchange shares, and the signatures of all registered account holders.
Send the exchange request to Morgan  Stanley Institutional Fund, Inc., P.O.  Box
2798, Boston, Massachusetts 02208-2798.
 
BY TELEPHONE
 
   
    When  exchanging shares by  telephone, have ready the  name, class of shares
and account number of the current Portfolio, the name(s) of the portfolio(s) and
class(es) of  shares into  which  you intend  to  exchange shares,  your  Social
Security  number  or Tax  I.D. number,  and your  account address.  Requests for
telephone exchanges received prior to 4:00 p.m. (Eastern Time) are processed  at
the  close  of business  that  same day  based  on the  net  asset value  of the
class(es) of the portfolios  at the close of  business. Requests received  after
4:00  p.m. (Eastern Time) are  processed the next business  day based on the net
asset value determined  at the  close of business  on such  day. For  additional
information   regarding  responsibility  for   the  authenticity  of  telephoned
instructions, see "Redemption of Shares -- By Telephone" above.
    
 
TRANSFER OF REGISTRATION
 
    You may transfer the registration of any of your Portfolio shares to another
person by writing  to Morgan Stanley  Institutional Fund, Inc.,  P.O. Box  2798,
Boston,  Massachusetts 02208-2798.  As in the  case of  redemptions, the written
request must  be  received  in good  order  before  any transfer  can  be  made.
Transferring  the  registration of  shares may  affect  the eligibility  of your
account for a given class of a Portfolio's shares and may result in  involuntary
conversion or redemption of your shares. See "Purchase of Shares" above.
 
                              VALUATION OF SHARES
 
   
    The net asset value per share of a class of shares of each of the Portfolios
is  determined by dividing the total market value of the Portfolio's investments
and other assets attributable to  such class, less any liabilities  attributable
to  such class, by the  total number of outstanding shares  of such class of the
Portfolio. Net  asset  value  is  calculated separately  for  each  class  of  a
Portfolio.  Net asset value per  share is determined as  of the regular close of
the NYSE on each day  that the NYSE is open  for business. Price information  on
listed  securities is  taken from the  exchange where the  security is primarily
traded. Securities  listed  on  a  U.S. securities  exchange  for  which  market
quotations are available are valued at the last quoted sale price on the day the
valuation  is made. Securities listed on a  foreign exchange are valued at their
closing price.  Unlisted securities  and  listed securities  not traded  on  the
valuation date for which market quotations are readily available are valued at a
price  within a range  not exceeding the  current asked price  nor less than the
current bid price. The current bid and asked prices are determined based on  the
average  of the bid and asked prices  quoted on such valuation date by reputable
brokers.
    
 
    Bonds and other fixed income securities are valued according to the broadest
and most representative  market, which will  ordinarily be the  over-the-counter
market.  Net asset value includes interest  on fixed income securities, which is
accrued daily.  In addition,  bonds and  other fixed  income securities  may  be
valued on the basis of prices provided by a pricing service when such prices are
believed  to  reflect  the fair  market  value  of such  securities.  The prices
provided by a pricing service are determined without regard to bid or last  sale
prices,  but take into account institutional-size,  trading in similar groups of
securities and any developments related to the
 
                                       34
<PAGE>
specific securities. Securities not priced in this manner are valued at the most
recently quoted bid price or, when  securities exchange valuations are used,  at
the  latest quoted  sale price  on the  day of  valuation. If  there is  no such
reported sale, the latest  quoted bid price will  be used. Securities  purchased
with remaining maturities of 60 days or less are valued at amortized cost, if it
approximates market value. In the event that amortized cost does not approximate
market value, market prices as determined above will be used.
 
   
    The  value  of other  assets  and securities  for  which quotations  are not
readily available  (including restricted  and unlisted  foreign securities)  and
those securities for which it is inappropriate to determine prices in accordance
with  the above-stated  procedures are  determined in  good faith  at fair value
using methods determined by the Board of Directors. For purposes of  calculating
net  asset value  per share, all  assets and liabilities  initially expressed in
foreign currencies will be translated into U.S.  dollars at the mean of the  bid
and  asked price of such currencies against the U.S. dollar as quoted by a major
bank.
    
 
    Although the legal rights of Class A  and Class B shares will be  identical,
the  different expenses borne by  each class will result  in different net asset
values and dividends for the class.  Dividends will differ by approximately  the
amount  of the distribution expense accrual  differential among the classes. The
net asset value of  Class B shares  will generally be lower  than the net  asset
value  of the Class A shares as a  result of the distribution expense charged to
Class B shares.
 
                            PERFORMANCE INFORMATION
 
    The Fund may from time to time advertise total return for each class of  the
Portfolios.  THESE FIGURES ARE BASED ON HISTORICAL EARNINGS AND ARE NOT INTENDED
TO INDICATE FUTURE PERFORMANCE.
 
    Each of the  Portfolios may  advertise "total  return" which  shows what  an
investment  in a class of a Portfolio  would have earned over a specified period
of time (such as one,  five or ten years),  assuming that all distributions  and
dividends by the Portfolio were reinvested in the same class on the reinvestment
dates  during the period. Total return does not take into account any federal or
state income taxes  that may  be payable on  dividends and  distributions or  on
redemption.  The Fund  may also  include comparative  performance information in
advertising or  marketing the  Portfolios' shares,  including data  from  Lipper
Analytical  Services, Inc.,  other industry  publications, business periodicals,
rating services and market indices.
 
    The performance figures  for Class  B shares  will generally  be lower  than
those  for Class  A shares because  of the  distribution fee charged  to Class B
shares.
 
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
 
    All income dividends and capital gains  distributions for a class of  shares
will be automatically reinvested in additional shares at net asset value, except
that,  upon written notice to the Fund or by checking off the appropriate box in
the Distribution Option Section on the Account Registration Form, a  shareholder
may elect to receive income dividends and capital gains distributions in cash.
 
   
    The  Emerging  Growth  and  the  MicroCap  Portfolios  expect  to distribute
substantially all of their taxable net  investment income in the form of  annual
dividends   and  the  Equity   Growth  and  the   Aggressive  Equity  Portfolios
    
 
                                       35
<PAGE>
expect to distribute  substantially all of  their net investment  income in  the
form  of quarterly  dividends. Net  realized gains  for each  Portfolio, if any,
after  reduction  for  any  available  tax  loss  carryforwards  will  also   be
distributed annually.
 
    Undistributed  net  investment income  is included  in each  Portfolio's net
assets for the purpose of calculating  net asset value per share. Therefore,  on
the  "ex-dividend" date,  the net  asset value  per share  excludes the dividend
(i.e., is  reduced by  the per  share amount  of the  dividend). Dividends  paid
shortly after the purchase of shares by an investor, although in effect a return
of capital, are taxable to shareholders subject to income tax.
 
   
    Because  of  the  distribution  fee  and  any  other  expenses  that  may be
attributable to  the Class  B shares,  the net  income attributable  to and  the
dividends  payable  on  Class  B  shares  will  be  lower  than  the  net income
attributable to and the dividends  payable on Class A  shares. As a result,  the
net asset value per share of the classes of the Portfolios will differ at times.
Expenses  of the Portfolios  allocated to a  particular class of  shares will be
borne on a pro rata basis by each outstanding share of that class.
    
 
                                     TAXES
 
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
 
    No attempt has been made to  present a detailed explanation of the  federal,
state,  or  local  income tax  treatment  of  a Portfolio  or  its shareholders.
Accordingly, shareholders  are urged  to consult  their tax  advisors  regarding
specific questions as to federal, state and local income taxes.
 
    Each  Portfolio  is treated  as  a separate  entity  for federal  income tax
purposes and is not  combined with the Fund's  other portfolios. Each  Portfolio
intends  to qualify for the special  tax treatment afforded regulated investment
companies under Subchapter M of the Code, so that the Portfolio will be relieved
of federal income tax on that part of its net investment income and net  capital
gain that is distributed to shareholders.
 
   
    Each  Portfolio intends to  distribute substantially all  of its taxable net
investment income (including, for this purpose, net short-term capital gain)  to
shareholders.  Dividends from a Portfolio's net investment income are taxable to
shareholders as  ordinary income,  whether  received in  cash or  in  additional
shares.  Such dividends paid by  a Portfolio will generally  qualify for the 70%
dividends-received deduction for  corporate shareholders only  to the extent  of
the  aggregate qualifying  dividend income received  by the  Portfolio from U.S.
corporations. Each Portfolio will report annually to its shareholders the amount
of dividend income qualifying for such treatment.
    
 
    Distributions of net capital gain (the excess of net long-term capital  gain
over  net  short-term capital  loss) are  taxable  to shareholders  as long-term
capital gain, regardless of how long  shareholders have held their shares.  Each
Portfolio  will send reports annually to  its shareholders of the federal income
tax status of all distributions made during the preceding year.
 
    Each  Portfolio  intends   to  make  sufficient   distributions  or   deemed
distributions  of its ordinary income and capital gain net income (the excess of
short-term and  long-term capital  gain over  short-term and  long-term  capital
loss,  including any available capital loss  carryforwards), prior to the end of
each calendar year to avoid liability for federal excise tax.
 
                                       36
<PAGE>
    Dividends and  other  distributions  declared by  a  Portfolio  in  October,
November or December of any year and payable to shareholders of record on a date
in  such month will be deemed to have been paid by the Portfolio and received by
the shareholders in that year if the distributions are paid by the Portfolio  at
any time during the following January.
 
   
    The  Fund may be required to withhold and  remit to the U.S. Treasury 31% of
any dividends, capital gains distributions  and redemption proceeds paid to  any
individual  or certain  other non-corporate  shareholder (1)  who has  failed to
provide a  correct taxpayer  identification  number (generally  an  individual's
social  security number  or non-individual's employer  identification number) on
the Application Form, (2) who is  subject to backup withholding by the  Internal
Revenue  Service, or (3) who has not certified to the Fund that such shareholder
is not  subject  to  backup  withholding. This  backup  withholding  is  not  an
additional   tax,  and  any  amounts  withheld   may  be  credited  against  the
shareholder's ultimate U.S. tax liability.
    
 
    The sale, exchange or  redemption of shares will  result in taxable gain  or
loss to the selling, exchanging or redeeming shareholder, depending upon whether
the fair market value of the sale, exchange or redemption proceeds exceeds or is
less  than the shareholder's  adjusted basis in the  sold, exchanged or redeemed
shares. If capital gain distributions have been made with respect to shares that
are sold at a loss  after being held for six  months or less, however, then  the
loss  is treated as a  long-term capital loss to the  extent of the capital gain
distributions.
 
    Conversion  of  shares  between  classes  are  not  taxable  events  to  the
shareholder.
 
    Shareholders  are urged  to consult with  their tax  advisors concerning the
application of state and local income taxes to investments in a Portfolio, which
may differ from the federal income tax consequences described above.
 
    Investment income  received  by  a Portfolio  from  sources  within  foreign
countries  may be subject to foreign income taxes withheld at the source. To the
extent that a Portfolio is  liable for foreign income  taxes so withheld, it  is
not  expected that  a Portfolio  or its  shareholders would  be able  to claim a
credit for U.S. tax purposes with respect to any such foreign taxes.
 
    THE TAX DISCUSSION SET FORTH ABOVE IS INCLUDED FOR GENERAL INFORMATION ONLY.
PROSPECTIVE INVESTORS SHOULD CONSULT THEIR OWN TAX ADVISERS WITH RESPECT TO  THE
TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN A PORTFOLIO.
 
                                       37
<PAGE>
                             PORTFOLIO TRANSACTIONS
 
    The  Adviser selects the brokers or  dealers that will execute the purchases
and sales  of investment  securities  for each  of  the Fund's  portfolios.  The
Adviser  seeks the best execution of all portfolio transactions. A portfolio may
pay higher commission rates than the lowest available when the Adviser  believes
it  is reasonable to do  so in light of the  value of the research, statistical,
and pricing services provided by the broker effecting the transaction.
 
    It is not the Fund's practice to allocate brokerage or principal business on
the basis of sales of shares which  may be made through intermediary brokers  or
dealers.  However, the Adviser may, consistent  with NASD rules, place portfolio
orders with qualified broker-dealers who  recommend the applicable portfolio  to
their  clients or who act  as agents in the purchase  of shares of the portfolio
for their clients.
 
    Subject to  the overriding  objective  of obtaining  the best  execution  of
orders,  the Fund  may use  broker-dealer affiliates  of the  Adviser, including
Morgan Stanley,  to effect  portfolio  brokerage transactions  under  procedures
adopted  by the Fund's Board of Directors. For such transactions, the commission
rates and other remuneration paid to Morgan Stanley or other affiliates must  be
fair  and  reasonable  in  comparison  to  those  of  other  broker-dealers  for
comparable transactions  involving similar  securities being  purchased or  sold
during a comparable time period.
 
PORTFOLIO TURNOVER
 
   
    The  Portfolios  generally do  not invest  for short-term  trading purposes,
however,  when  circumstances  warrant,  each  Portfolio  may  sell   investment
securities  without regard  to the  length of time  they have  been held. Market
conditions in a given year could result in a higher or lower portfolio  turnover
rate  than expected and the Portfolios will not consider portfolio turnover rate
a  limiting  factor  in  making  investment  decisions  consistent  with   their
respective objectives and policies. For the fiscal year ended December 31, 1996,
the Equity Growth and Aggressive Equity Portfolios had a portfolio turnover rate
of  186% and 380%, respectively. As portfolio turnover increases, the Portfolios
may expect  to pay  correspondingly increased  brokerage and  trading costs.  In
addition  to  transaction costs,  higher portfolio  turnover  may result  in the
realization of capital  gains. As  discussed under  "Taxes," to  the extent  net
short-term  capital gains  are realized,  any distributions  resulting from such
gains are considered ordinary income for federal income tax purposes.
    
 
                              GENERAL INFORMATION
 
DESCRIPTION OF COMMON STOCK
 
   
    The Fund  was organized  as a  Maryland corporation  on June  16, 1988.  The
Articles  of Incorporation, as amended and restated, permit the Fund to issue up
to 35 billion shares of common stock,  with $.001 par value per share.  Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number  of shares the  Fund is authorized  to issue without  the approval of the
shareholders of the Fund. The Board of Directors has the power to designate  one
or  more classes of  shares of common  stock and to  classify and reclassify any
unissued shares with respect to such classes. The shares of common stock of each
Portfolio are currently classified into two classes, the Class A shares and  the
Class B shares.
    
 
    The   shares  of   the  Portfolios,  when   issued,  will   be  fully  paid,
nonassessable, fully transferable and  redeemable at the  option of the  holder.
The  shares have no preference as to conversion, exchange, dividends, retirement
 
                                       38
<PAGE>
or other features and have no  pre-emptive rights. The shares of each  Portfolio
have non-cumulative rights, which means that the holders of more than 50% of the
shares  voting for the election of Directors  can elect 100% of the Directors if
they choose  to do  so.  Persons or  organizations owning  25%  or more  of  the
outstanding  shares of a Portfolio  may be presumed to  "control" (as defined in
the 1940 Act) such Portfolio.  Under Maryland law, the  Fund is not required  to
hold  an annual meeting of  its shareholders unless required  to do so under the
1940 Act.
 
REPORTS TO SHAREHOLDERS
 
    The Fund will send to its  shareholders annual and semi-annual reports;  the
financial  statements  appearing in  annual reports  are audited  by independent
accountants. Monthly unaudited portfolio  data is also  available from the  Fund
upon request.
 
    In  addition, the Adviser or its agent, as Transfer Agent, will send to each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
 
CUSTODIAN
 
    Chase is the Fund's custodian for domestic and certain foreign assets. Chase
is not an  affiliate of  the Adviser or  the Distributor.  Morgan Stanley  Trust
Company,  Brooklyn,  New York  ("MSTC"),  an affiliate  of  the Adviser  and the
Distributor, acts as  the Fund's custodian  for assets held  outside the  United
States  and employs subcustodians approved by the Board of Directors of the Fund
in accordance with regulations  of the Commission for  the purpose of  providing
custodial  services for such assets. MSTC  may also hold certain domestic assets
for the Fund. For more information  on the custodians, see "General  Information
- -- Custody Arrangements" in the Statement of Additional Information.
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
    Chase   Global   Funds  Services   Company,   73  Tremont   Street,  Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
 
INDEPENDENT ACCOUNTANTS
 
   
    Price Waterhouse  LLP serves  as independent  accountants for  the Fund  and
audits the annual financial statements of each Portfolio.
    
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       39
<PAGE>
   MORGAN STANLEY INSTITUTIONAL FUND, INC.
          EQUITY GROWTH, EMERGING GROWTH,
           MICROCAP AND AGGRESSIVE EQUITY PORTFOLIOS
           P.O. BOX 2798, BOSTON, MA 02208-2798
 
                           ACCOUNT REGISTRATION FORM
 
<TABLE>
<C>   <S>                                                           <C>
                                                                    If you need assistance in filling out this form for the
      ACCOUNT INFORMATION                                           Morgan Stanley Institutional Fund, please contact your
      Fill in where applicable                                      Morgan Stanley representative or call us toll free
                                                                    1-(800)-548-7786. Please print all items except signature,
                                                                    and mail to the Fund at the address above.
  A)  REGISTRATION
      1. INDIVIDUAL
      2. JOINT TENANTS
         (RIGHTS OF SURVIVORSHIP PRESUMED UNLESS
         TENANCY IN COMMON
         IS INDICATED)
</TABLE>
 
1.
                               First
Name                          Initial                               Last Name
2.
                               First
Name                          Initial                               Last Name
                               First
Name                          Initial                               Last Name
 
<TABLE>
<C>   <S>                                       <C>
      3. CORPORATIONS,
         TRUSTS AND OTHERS
         Please call the Fund for additional
      documents that may be required to set up
      account and to authorize transactions.
</TABLE>
 
3.
 
<TABLE>
<S>                    <C>               <C>                        <C>               <C>
Type of Registration:  / / INCORPORATED  / / UNINCORPORATED         / / PARTNERSHIP   / / UNIFORM GIFT/TRANSFER TO MINOR
                                         ASSOCIATION                                    (ONLY ONE CUSTODIAN AND MINOR PERMITTED)
</TABLE>
 
/ / TRUST ________________________  / / OTHER (Specify) ________________________
 
<TABLE>
<C>   <S>                                       <C>
  B)  MAILING ADDRESS
      Please fill in completely, including
      telephone number(s).
</TABLE>
 
/ / United States Citizen  / / Resident Alien
                   Street or P.O. Box
                   City
                   State                   Zip
Home Telephone No.                   Business Telephone No.
 
/ / Non-Resident Alien:
Permanent Address (Where you reside permanently for tax purposes)
                   Street Address
                   City
                   Country                   Postal Code
Home Telephone No.                    Business Telephone No.
 
Current Mailing Address (If different from Permanent Address)
                   Street Address
                   City
                   Country
Postal Code
Home Telephone No.                   Business Telephone No.
 
<TABLE>
<C>   <S>                                       <C>                             <C>
 
  C)  TAXPAYER                                  Enter your Taxpayer Identification Number. For most individual
      IDENTIFICATION                            taxpayers, this is your Social Security Number. OR
      NUMBER                                                                    SOCIAL SECURITY NUMBER
      1. INDIVIDUAL                             1.         TAXPAYER             ("SSN")
      2. JOINT TENANTS                          IDENTIFICATION NUMBER           ------------- -------------
         (RIGHTS OF SURVIVORSHIP PRESUMED       ("TIN")                         ------------- - - - - - - - -
      UNLESS                                    ------------ ------------       -
                                                ------------ - - - - - - - -
                                                -
                                                --
         TENANCY IN COMMON                      --        --                    OR
         IS INDICATED)                                                                                         SSN
 
      For Custodian account                     2.    TIN        - - - - - - -  ------------- -------------
      of a minor (Uniform                       -- - - -                        ------------- - - - - - - - -
      Gifts/Transfers to Minor                                                  -
                                                                                OR
                                                --
 
      Acts), give the Social                    --        --     TIN        -                                  SSN
      Security Number of                        -- - - - - - - - - -            ------------- -------------
      the minor                                                                 ------------- - - - - - - - -
                                                                                -
                                                IMPORTANT TAX INFORMATION
                                                --
                                                --        --
                                                You  (as a payee) are required by law to provide us (as payer)
                                                with your  correct  TIN(s) or  SSN(s).  Accounts that  have  a
                                                missing  or  incorrect TIN(s)  or  SSN(s) will  be  subject to
                                                backup withholding at a  31% rate on dividends,  distributions
                                                and  other payments.  If you  have not  provided us  with your
                                                correct TIN(s) or SSN(s), you may be subject to a $50  penalty
                                                imposed by the Internal Revenue Service.
                                                Backup withholding is not an additional tax; the tax liability
                                                of  persons subject to  backup withholding will  be reduced by
                                                the amount  of  tax withheld.  If  withholding results  in  an
                                                overpayment    of   taxes,   a   refund   may   be   obtained.
                                                You may be notified that you are subject to backup withholding
                                                under Section  3406(a)(1)(C)  of  the  Internal  Revenue  Code
                                                because  you have  underreported interest or  dividends or you
                                                were required to,  but failed  to, file a  return which  would
                                                have included a reportable interest or dividend payment.
</TABLE>
 
<PAGE>
 
   
<TABLE>
<C>   <S>                                       <C>                             <C>                   <C>
  D)  PORTFOLIO AND                             For Purchase of the following   / / Class A Shares $  / / Class B Shares $
      CLASS SECTION                             Portfolio(s):                   / / Class A Shares $  / / Class B Shares $
      (Class A shares minimum $500,000 for      Equity Growth Portfolio         / / Class A Shares $  / / Class B Shares $
      each Portfolio and Class B shares         Emerging Growth Portfolio       / / Class A Shares $  / / Class B Shares $
      minimum $100,000 for each Portfolio).     MicroCap Portfolio
      Please indicate Portfolio, class and      Aggressive Equity Portfolio
      amount.
                                                                                Total Initial Investment $
</TABLE>
    
 
<TABLE>
<C>   <S>                                       <C>
  E)  METHOD OF
      INVESTMENT
      Please indicate portfolio, manner of
      payment.
</TABLE>
 
Payment by:
 
/ / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND,
INC.--PORTFOLIO NAME)
 
<TABLE>
<S>                                                                                 <C>
/ / Exchange $ From                                                                           -- - - - - - - - - - -- - -
                                                                Name of Portfolio                     Account No.
/ / Account previously established by:  / / Phone exchange  / / Wire on                       -- - - - - - - - - - -- - -
                                                                                            Account No.               (Check
                                                                                      (Previously assigned by the Fund)     Digit)
                                                                            Date
</TABLE>
 
<TABLE>
<C>   <S>                                       <C>
  F)  DISTRIBUTION                              Income dividends and capital gains distributions (if any) to
      OPTION                                    be reinvested in additional shares unless either box below
                                                is checked.
                                                / / Income dividends to be paid in cash, capital gains
                                                distributions (if any) in shares.
                                                / / Income dividends and capital gains distributions (if
                                                any) to be paid in cash.
</TABLE>
<TABLE>
<C>   <S>                             <C>
  G)  TELEPHONE                       / / I/we hereby authorize the Fund and
      REDEMPTION                      its agents to honor any telephone
      AND EXCHANGE                    requests to wire redemption proceeds to
      OPTION                          the commercial bank indicated at right
      Please select at time of        and/or mail redemption proceeds to the
      initial application if you      name and address in which my/our fund
      wish to redeem or exchange      account is registered if such requests
      shares by telephone. A          are believed to be authentic.
      SIGNATURE GUARANTEE IS          The Fund and the Fund's Transfer Agent
      REQUIRED IF BANK ACCOUNT IS     will employ reasonable procedures to
      NOT REGISTERED IDENTICALLY TO   confirm that instructions communicated
      YOUR FUND ACCOUNT.              by telephone are genuine. These
      TELEPHONE REQUESTS FOR          procedures include requiring the
      REDEMPTIONS OR EXCHANGE WILL    investor to provide certain personal
      NOT BE HONORED UNLESS THE BOX   identification information at the time
      IS CHECKED.                     an account is opened and prior to
                                      effecting each transaction requested by
                                      telephone. In addition, all telephone
                                      transaction requests will be recorded
                                      and investors may be required to provide
                                      additional telecopied written
                                      instructions of transaction requests.
                                      Neither the Fund nor the Transfer Agent
                                      will be responsible for any loss,
                                      liability, cost or expense for following
                                      instructions received by telephone that
                                      it reasonably believes to be genuine.
 
<CAPTION>
  G)
      Name of COMMERCIAL Bank (Not Savings Bank)
      Bank Account No.
                                                   Bank ABA No.
      Name(s) in which your BANK Account is Established
      Bank's Street Address
      City                           State                           Zip
</TABLE>
 
   
<TABLE>
<C>   <S>                                       <C>
  H)  INTERESTED PARTY                          Name
      OPTION                                    Address
      In addition to the account statement      City         State         Zip Code
      sent to my/our registered address, I/we
      hereby authorize the Fund to mail
      duplicate statements to the name and
      address provided at right.
</TABLE>
    
 
<TABLE>
<C>   <S>                                       <C>
  I)  DEALER
      INFORMATION
                                                Representative Name                        Representative
                                                No.                            Branch
                                                No.
</TABLE>
 
<TABLE>
<C>   <S>                        <C>
  J)  SIGNATURE OF
      ALL HOLDERS
      AND TAXPAYER
      CERTIFICATION
      Sign Here ,
</TABLE>
 
<TABLE>
<S>                                  <C>
The undersigned certify that I/we have full authority and legal capacity
to purchase and redeem shares of the Fund and affirm that I/we have
received a current Prospectus of the Morgan Stanley Institutional Fund,
Inc. and agree to be bound by its terms.
  BY  SIGNING THIS APPLICATION,  I/WE HEREBY CERTIFY  UNDER PENALTIES OF
PERJURY THAT THE INFORMATION ON THIS APPLICATION IS COMPLETE AND CORRECT
AND THAT  AS REQUIRED  BY  FEDERAL LAW  (PLEASE CHECK  APPLICABLE  BOXES
BELOW):
/ / U.S. CITIZEN(S)/TAXPAYER(S):
       /  / I/WE CERTIFY THAT (1) THE NUMBER(S) SHOWN ABOVE ON THIS FORM
           IS/ARE THE  CORRECT SSN(S)  OR TIN(S)  AND (2)  I/WE ARE  NOT
           SUBJECT TO ANY BACKUP WITHHOLDING EITHER BECAUSE (A) I/WE ARE
           EXEMPT  FROM  BACKUP  WITHHOLDING;  (B)  I/WE  HAVE  NOT BEEN
           NOTIFIED BY THE  INTERNAL REVENUE SERVICE  ("IRS") THAT  I/WE
           ARE SUBJECT TO BACKUP WITHHOLDING AS A RESULT OF A FAILURE TO
           REPORT ALL INTEREST OR DIVIDENDS; OR (C) THE IRS HAS NOTIFIED
           ME/US   THAT  I  AM/WE  ARE   NO  LONGER  SUBJECT  TO  BACKUP
           WITHHOLDING.
       / / IF  NO TIN(S) OR  SSN(S) HAS/HAVE BEEN  PROVIDED ABOVE,  I/WE
           HAVE  APPLIED, OR INTEND  TO APPLY, TO THE  IRS OR THE SOCIAL
           SECURITY  ADMINISTRATION  FOR  A  TIN  OR  A  SSN  AND   I/WE
           UNDERSTAND THAT IF I/WE DO NOT PROVIDE EITHER NUMBER TO CHASE
           GLOBAL FUNDS SERVICES COMPANY ("CGFSC") WITHIN 60 DAYS OF THE
           DATE  OF THIS APPLICATION  OR IF I/WE  FAIL TO FURNISH MY/OUR
           CORRECT SSN(S) OR TIN(S),  I/WE MAY BE  SUBJECT TO A  PENALTY
           AND  A 31% BACKUP WITHHOLDING ON DISTRIBUTIONS AND REDEMPTION
           PROCEEDS. (PLEASE PROVIDE EITHER NUMBER ON IRS FORM W-9). YOU
           MAY REQUEST SUCH FORM BY CALLING CGFSC AT 800-282-4404.
/ / NON-U.S. CITIZEN(S)/TAXPAYER(S)
  UNDER PENALTIES  OF  PERJURY, I/WE  CERTIFY  THAT I/WE  ARE  NOT  U.S.
CITIZENS  OR RESIDENTS AND I/WE ARE EXEMPT FOREIGN PERSONS AS DEFINED BY
THE INTERNAL REVENUE SERVICE.
 
THE INTERNAL  REVENUE  SERVICE DOES  NOT  REQUIRE YOUR  CONSENT  TO  ANY
PROVISION  OF THIS  DOCUMENT OTHER  THAN THE  CERTIFICATIONS REQUIRED TO
AVOID BACKUP WITHHOLDING.
 
                                     (X)
(X)                                  Signature (if joint account, both
Signature                                                     Date must sign)              Date
</TABLE>
<PAGE>
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
 
  NO  DEALER, SALES  REPRESENTATIVE OR ANY  OTHER PERSON HAS  BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE  CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS  HAVING BEEN AUTHORIZED BY THE FUND  OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF  THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION  TO
ANY  PERSON TO WHOM  IT IS UNLAWFUL TO  MAKE SUCH OFFER  OR SOLICITATION IN SUCH
JURISDICTION.
 
                           --------------------------
 
                               TABLE OF CONTENTS
 
   
<TABLE>
<S>                                                 <C>
                                                    PAGE
                                                    ----
Fund Expenses.....................................    2
Financial Highlights..............................    5
Prospectus Summary................................    9
Investment Objectives and Policies................   13
Additional Investment Information.................   16
Investment Limitations............................   24
Management of the Fund............................   24
Purchase of Shares................................   27
Redemption of Shares..............................   32
Shareholder Services..............................   33
Valuation of Shares...............................   34
Performance Information...........................   35
Dividends and Capital Gains Distributions.........   35
Taxes.............................................   36
Portfolio Transactions............................   38
General Information...............................   38
Account Registration Form
</TABLE>
    
 
                            EQUITY GROWTH PORTFOLIO
                           EMERGING GROWTH PORTFOLIO
                               MICROCAP PORTFOLIO
                          AGGRESSIVE EQUITY PORTFOLIO
                               PORTFOLIOS OF THE
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
 
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
 
- ---------------------------------
- ---------------------------------
- ---------------------------------
- ---------------------------------
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
     ----------------------------------------------------------------------
 
                           U.S. REAL ESTATE PORTFOLIO
 
                                PORTFOLIO OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
 
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
 
                                ----------------
 
   
    Morgan  Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company, or mutual fund, which offers redeemable shares in
a   series   of   diversified   and   non-diversified   investment    portfolios
("portfolios").  The  Fund  is  designed  to  provide  clients  with  attractive
alternatives for meeting their investment needs. The Fund currently consists  of
twenty-nine  portfolios representing a  broad range of  investment choices. This
prospectus (the "Prospectus") pertains to the Class A and the Class B shares  of
the U.S. Real Estate Portfolio (the "Portfolio"). The Class A and Class B shares
currently   offered  by   the  Portfolio   have  different   minimum  investment
requirements and fund  expenses. Shares of  the portfolios are  offered with  no
sales  charge, exchange  fee or redemption  fee, (except  that the International
Small Cap Portfolio may impose a transaction fee).
    
 
    The Fund is designed  to meet the investment  needs of discerning  investors
who  place a premium on quality and  personal service. With Morgan Stanley Asset
Management  Inc.  as   Adviser  and   Administrator  (the   "Adviser"  and   the
"Administrator"),  and with Morgan Stanley & Co. Incorporated ("Morgan Stanley")
as Distributor, the  Fund makes available  to institutional and  high net  worth
individual  investors a series  of portfolios which  benefit from the investment
expertise and commitment to  excellence associated with  Morgan Stanley and  its
affiliates.
 
    This Prospectus is designed to set forth concisely the information about the
Fund  that a prospective investor should know  before investing and it should be
retained for future reference. The  Fund offers additional portfolios which  are
described  in other prospectuses and under  "Prospectus Summary" below. The Fund
currently offers the following portfolios:  (i) GLOBAL AND INTERNATIONAL  EQUITY
- --  Active Country Allocation, Asian  Equity, Emerging Markets, European Equity,
Global Equity, Gold, International  Equity, International Magnum,  International
Small  Cap, Japanese Equity  and Latin American Portfolios;  (ii) U.S. EQUITY --
Aggressive Equity,  Emerging  Growth, Equity  Growth,  Small Cap  Value  Equity,
Technology,  U.S Real Estate and Value Equity Portfolios; (iii) EQUITY AND FIXED
INCOME -- Balanced Portfolio; (iv) FIXED INCOME -- Emerging Markets Debt,  Fixed
Income,  Global Fixed Income, High Yield  and Municipal Bond Portfolios; and (v)
MONEY MARKET -- Money Market  and Municipal Money Market Portfolios.  Additional
information   about  the  Fund  is  contained  in  a  "Statement  of  Additional
Information" dated May 1, 1997, which  is incorporated herein by reference.  The
Statement of Additional Information and the prospectuses pertaining to the other
portfolios  of the Fund are available upon request and without charge by writing
or calling the Fund at the address and telephone number set forth above.
 
THESE SECURITIES HAVE NOT BEEN APPROVED  OR DISAPPROVED BY THE SECURITIES  AND
  EXCHANGE  COMMISSION,  NOR  HAS THE  SECURITIES  AND  EXCHANGE COMMISSION
     PASSED UPON  THE  ACCURACY  OR  ADEQUACY  OF  THIS  PROSPECTUS.  ANY
               REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.
 
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1997.
<PAGE>
                                 FUND EXPENSES
 
   
    The  following table illustrates the expenses and fees that a shareholder of
the U.S. Real Estate Portfolio will incur:
    
 
<TABLE>
<CAPTION>
SHAREHOLDER TRANSACTION EXPENSES
- --------------------------------------------------
<S>                                                 <C>
Maximum Sales Load Imposed on Purchases
  Class A.........................................     None
  Class B.........................................     None
Maximum Sales Load Imposed on Reinvested Dividends
  Class A.........................................     None
  Class B.........................................     None
Deferred Sales Load
  Class A.........................................     None
  Class B.........................................     None
Redemption Fees
  Class A.........................................     None
  Class B.........................................     None
Exchange Fees
  Class A.........................................     None
  Class B.........................................     None
</TABLE>
 
   
<TABLE>
<CAPTION>
ANNUAL FUND OPERATING EXPENSES
- --------------------------------------------------
 (AS A PERCENTAGE OF AVERAGE NET ASSETS)
<S>                                                 <C>
Management Fee (Net of Fee Waiver)*
  Class A.........................................    0.65%
  Class B.........................................    0.65%
12b-1 Fees
  Class A.........................................     None
  Class B.........................................    0.25%
Other Expenses
  Class A.........................................    0.35%
  Class B.........................................    0.35%
                                                    ---------
Total Operating Expenses (Net of Fee Waivers)*
  Class A.........................................    1.00%
  Class B.........................................    1.25%
                                                    ---------
                                                    ---------
</TABLE>
    
 
- ------------------------
   
*The Adviser  has agreed  to  waive its  management  fees and/or  reimburse  the
 Portfolio,  if necessary, if  such fees would cause  the total annual operating
 expenses of the Portfolio  to exceed a specified  percentage of its  respective
 average  daily net assets. Absent  the fee waiver, the  management fee would be
 0.80%. Absent  the fee  waiver and/or  expense reimbursement,  the  Portfolio's
 total  operating expenses would be 1.14% of the average daily net assets of the
 Class A shares and 1.37% of the average daily net assets of the Class B shares.
 As a result of this  reduction, the Management Fee  stated above is lower  than
 the contractual fee stated under "Management of the Fund." The Adviser reserves
 the  right to terminate any of its fee waivers and/or expense reimbursements at
 any time in its sole discretion. For further information on Fund expenses,  see
 "Management of the Fund."
    
 
                                       2
<PAGE>
    The  purpose of the table  above is to assist  the investor in understanding
the various expenses  that an investor  in the Portfolio  will bear directly  or
indirectly.  Expenses and fees are based on  actual figures for the period ended
December 31, 1996. Due to  the continuous nature of  Rule 12b-1 fees, long  term
Class  B shareholders may pay more than  the equivalent of the maximum front-end
sales charges  otherwise permitted  by the  National Association  of  Securities
Dealers, Inc. ("NASD") Conduct Rules.
 
    The  following  example illustrates  the expenses  that you  would pay  on a
$1,000 investment assuming (1) a 5% annual rate of return and (2) redemption  at
the  end of each time period. As noted in the table above, the Portfolio charges
no redemption fees of any kind. The example is based on total operating expenses
of the Portfolio after fee waivers.
 
   
<TABLE>
<CAPTION>
                                                                      1 YEAR      3 YEARS      5 YEARS     10 YEARS
                                                                     ---------  -----------  -----------  -----------
<S>                                                                  <C>        <C>          <C>          <C>
U.S. Real Estate Portfolio
  Class A..........................................................  $      10   $      32    $      55    $     122
  Class B..........................................................         13          40           69          151
</TABLE>
    
 
    THIS EXAMPLE SHOULD  NOT BE CONSIDERED  A REPRESENTATION OF  PAST OR  FUTURE
EXPENSES  OR  PERFORMANCE. ACTUAL  EXPENSES MAY  BE GREATER  OR LESS  THAN THOSE
SHOWN.
 
                                       3
<PAGE>
                              FINANCIAL HIGHLIGHTS
 
   
    The following table provides financial highlights for the Class A and  Class
B  shares  of the  Portfolio  for each  of  the periods  presented.  The audited
financial highlights  for  the  Portfolio's  shares  for  each  of  the  periods
presented are part of the Fund's financial statements which appear in the Fund's
December  31, 1996 Annual  Report to Shareholders and  which are incorporated by
reference in the  Fund's Statement  of Additional  Information. The  Portfolio's
financial  highlights for  each of  the periods  presented have  been audited by
Price Waterhouse LLP, whose unqualified  report thereon is also incorporated  by
reference  in the  Statement of  Additional Information.  Additional performance
information is  included  in  the  Annual Report.  The  Annual  Report  and  the
financial   statements  therein,   along  with   the  Statement   of  Additional
Information, are available at no cost from the Fund at the address and telephone
number noted on  the cover page  of this Prospectus.  The following  information
should be read in conjunction with the financial statements and notes thereto.
    
 
                                       4
<PAGE>
                           U.S. REAL ESTATE PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                                    CLASS B
                                                           CLASS A                 ---------
                                                  --------------------------        PERIOD
                                                                    PERIOD           FROM
                                                                     FROM           JANUARY
                                                                   FEBRUARY           2,
                                                                   24, 1995*        1996***
                                                  YEAR ENDED          TO              TO
                                                   DECEMBER        DECEMBER        DECEMBER
                                                   31, 1996        31, 1995        31, 1996
                                                  ----------       ---------       ---------
<S>                                               <C>              <C>             <C>
NET ASSET VALUE, BEGINNING OF PERIOD.........     $11.42           $10.00          $11.50
                                                  ----------       ---------       ---------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)..................       0.37            0.26            0.35
  Net Realized and Unrealized Gain on
   Investments...............................       4.02            1.84            3.92
                                                  ----------       ---------       ---------
    Total from Investment Operations.........       4.39            2.10            4.27
                                                  ----------       ---------       ---------
DISTRIBUTIONS
  Net Investment Income......................      (0.39)          (0.24)          (0.37)
  Net Realized Gain..........................      (1.01)          (0.44)          (1.01)
                                                  ----------       ---------       ---------
    Total Distributions......................      (1.40)          (0.68)          (1.38)
                                                  ----------       ---------       ---------
NET ASSET VALUE, END OF PERIOD...............     $14.41           $11.42          $14.39
                                                  ----------       ---------       ---------
                                                  ----------       ---------       ---------
TOTAL RETURN.................................      39.56%          21.07%          38.23%
                                                  ----------       ---------       ---------
                                                  ----------       ---------       ---------
RATIOS AND SUPPLEMENTAL DATA:
  Net Assets, End of Period (Thousands)......     $210,368         $69,509         $8,734
  Ratio of Expenses to Average Net
   Assets (1)................................       1.00%           1.00%**         1.25%**
  Ratio of Net Investment Income to Average
   Net Assets (1)............................       3.08%           4.04%**         2.91%**
  Portfolio Turnover Rate....................        171%            158%            171%
  Average Commission Rate#...................     $0.0568            N/A           $0.0568
</TABLE>
    
 
- ------------------------------
 
   
<TABLE>
<C>  <S>                                       <C>             <C>           <C>
(1)  Effect of voluntary expense limitation
      during the period:
       Per share benefit to net investment
        income...............................      $0.02           $0.02         $0.02
     Ratios before expense limitation:
       Expenses to Average Net Assets........          1.14 %       1.33  %**      1.37  %**
       Net Investment Income to Average Net
        Assets...............................          2.93 %       3.71  %**      2.79  %**
</TABLE>
    
 
   
  * Commencement of operations.
    
 
   
 ** Annualized.
    
 
   
*** The Portfolio began offering Class B Shares on January 2, 1996.
    
 
   
 # Beginning  with fiscal year  1996, the Portfolio is  required to disclose the
   average commission rate  per share  it paid  for portfolio  trades, on  which
   commisions were charged, during the period.
    
 
                                       5
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
 
    The   Fund  consists  of   twenty-nine  portfolios,  offering  institutional
investors and high net  worth individual investors a  broad range of  investment
choices coupled with the advantages of a no-load mutual fund with Morgan Stanley
and  its affiliates providing customized  services as Adviser, Administrator and
Distributor.  Each  portfolio  offers  Class  A  shares  and,  except  for   the
International  Small Cap,  Money Market  and Municipal  Money Market Portfolios,
also offers Class B shares. Each portfolio has its own investment objective  and
policies  designed to meet  its specific goals. The  investment objective of the
U.S. Real Estate Portfolio is as follows:
 
    - The U.S.  REAL ESTATE  PORTFOLIO seeks  to provide  above average  current
     income  and long-term capital appreciation by investing primarily in equity
     securities of companies in  the U.S. real  estate industry, including  real
     estate investment trusts.
 
    The  other portfolios of the Fund  are described in other prospectuses which
may be obtained from the Fund at the address and phone number noted on the cover
page of this Prospectus. The investment objectives of these other portfolios are
listed below:
 
    GLOBAL AND INTERNATIONAL EQUITY:
 
    - The  ACTIVE   COUNTRY  ALLOCATION   PORTFOLIO  seeks   long-term   capital
     appreciation  by investing in accordance with country weightings determined
     by the  Adviser in  equity securities  of non-U.S.  issuers which,  in  the
     aggregate, replicate broad country indices.
 
    - The  ASIAN  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing primarily in equity securities of Asian issuers.
 
    - The CHINA GROWTH PORTFOLIO seeks to provide long-term capital appreciation
     by investing  primarily in  equity securities  of issuers  in The  People's
     Republic of China, Hong Kong and Taiwan.
 
    - The  EMERGING MARKETS  PORTFOLIO seeks  long-term capital  appreciation by
     investing primarily in equity securities of emerging country issuers.
 
    - The EUROPEAN  EQUITY PORTFOLIO  seeks  long-term capital  appreciation  by
     investing primarily in equity securities of European issuers.
 
    - The  GLOBAL  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation by
     investing primarily in equity securities  of issuers throughout the  world,
     including U.S. issuers.
 
    - The  GOLD  PORTFOLIO  seeks long-term  capital  appreciation  by investing
     primarily in equity securities of  foreign and domestic issuers engaged  in
     gold-related activities.
 
    - The INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation by
     investing primarily in equity securities of non-U.S. issuers.
 
    - The INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation by
     investing  primarily in equity securities  of non-U.S. issuers domiciled in
     EAFE countries.
 
    - The INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital appreciation
     by investing primarily in equity securities of non-U.S. issuers with equity
     market capitalizations of less than $1 billion.
 
                                       6
<PAGE>
    - The JAPANESE  EQUITY PORTFOLIO  seeks  long-term capital  appreciation  by
     investing primarily in equity securities of Japanese issuers.
 
   
    - The  LATIN  AMERICAN  PORTFOLIO seeks  long-term  capital  appreciation by
     investing primarily in  equity securities  of Latin  American issuers  and,
     from  time to time, debt securities  issued or guaranteed by Latin American
     governments or governmental entities.
    
 
    U.S. EQUITY:
 
    - The AGGRESSIVE EQUITY  PORTFOLIO seeks capital  appreciation by  investing
     primarily in corporate equity and equity-linked securities.
 
    - The  EMERGING  GROWTH PORTFOLIO  seeks  long-term capital  appreciation by
     investing primarily  in  growth-oriented  equity securities  of  small-  to
     medium-sized corporations.
 
    - The  EQUITY  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation by
     investing primarily  in growth-oriented  equity  securities of  medium  and
     large capitalization companies.
 
    - The  MICROCAP PORTFOLIO seeks long-term  capital appreciation by investing
     primarily in growth-oriented equity securities of small corporations.
 
    - The SMALL CAP VALUE EQUITY PORTFOLIO seeks high long-term total return  by
     investing  in  undervalued  equity  securities  of  small-  to medium-sized
     companies.
 
    - The TECHNOLOGY PORTFOLIO seeks long-term capital appreciation by investing
     primarily in equity  securities of companies  that, in the  opinion of  the
     Portfolio's   investment  adviser,  are  expected  to  benefit  from  their
     involvement in technology and technology-related industries.
 
    - The VALUE EQUITY PORTFOLIO seeks high total return by investing in  equity
     securities  which the  Adviser believes to  be undervalued  relative to the
     stock market in general at the time of purchase.
 
    EQUITY AND FIXED INCOME:
 
    - The BALANCED PORTFOLIO seeks high total return while preserving capital by
     investing in  a  combination of  undervalued  equity securities  and  fixed
     income securities.
 
    FIXED INCOME:
 
    - The  EMERGING MARKETS DEBT PORTFOLIO seeks  high total return by investing
     primarily  in  debt  securities   of  government,  government-related   and
     corporate issuers located in emerging countries.
 
    - The FIXED INCOME PORTFOLIO seeks to produce a high total return consistent
     with the preservation of capital by investing in a diversified portfolio of
     fixed income securities.
 
    - The GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real rate
     of  return while preserving capital by investing in fixed income securities
     of issuers throughout the world, including U.S. issuers.
 
    - The HIGH YIELD PORTFOLIO seeks to maximize total return by investing in  a
     diversified  portfolio of high  yield fixed income  securities that offer a
     yield above  that  generally available  on  debt securities  in  the  three
     highest rating categories of the recognized rating services.
 
    - The  MORTGAGE-BACKED SECURITIES PORTFOLIO seeks to produce as high a level
     of current income  as is  consistent with  the preservation  of capital  by
     investing  primarily  in  a  variety  of  investment-grade  mortgage-backed
     securities.
 
                                       7
<PAGE>
    - The MUNICIPAL BOND  PORTFOLIO seeks  to produce  a high  level of  current
     income  consistent with preservation  of principal through  by investing in
     municipal obligations, the interest on which is exempt from federal  income
     tax.
 
    MONEY MARKET:
 
    - The  MONEY MARKET PORTFOLIO seeks to  maximize current income and preserve
     capital while maintaining  high levels  of liquidity  through investing  in
     high quality money market instruments with remaining maturities of one year
     or less.
 
    - The  MUNICIPAL MONEY MARKET PORTFOLIO seeks to maximize current tax-exempt
     income and  preserve capital  while maintaining  high levels  of  liquidity
     through  investing in high quality  money market instruments with remaining
     maturities of one year or less which are exempt from federal income tax.
 
    THE CHINA  GROWTH, MICROCAP  AND MORTGAGE-BACKED  SECURITIES PORTFOLIOS  ARE
    CURRENTLY NOT BEING OFFERED.
 
INVESTMENT MANAGEMENT
 
   
    Morgan  Stanley Asset Management  Inc., a wholly  owned subsidiary of Morgan
Stanley Group Inc., which at March 31, 1997, together with its affiliated  asset
management  companies, had in excess of  $118 billion in assets under management
as an investment manager or as  a fiduciary adviser, acts as investment  adviser
to  the  Fund  and  each of  its  portfolios.  See "Management  of  the  Fund --
Investment Adviser" and "Management of the Fund -- Administrator."
    
 
HOW TO INVEST
 
    Class A shares  of the Portfolio  are offered directly  to investors at  net
asset  value with no  sales commission or  12b-1 charges. Class  B shares of the
Portfolio are offered at net  asset value with no  sales commission, but with  a
12b-1  fee, which  is accrued daily  and paid  quarterly, equal to  0.25% of the
Class B shares' average daily net assets on an annualized basis. Share purchases
may be  made  by  sending  investments  directly to  the  Fund  or  through  the
Distributor.  The minimum initial investment, generally, is $500,000 for Class A
shares of the Portfolio and  $100,000 for the Class  B shares of the  Portfolio.
The  minimum  initial investment  amount is  reduced  for certain  categories of
investors. For  additional information  on how  to purchase  shares and  minimum
initial investments, see "Purchase of Shares."
 
HOW TO REDEEM
 
    Shares  of the Portfolio may  be redeemed at any  time, without cost, at the
net asset value  per share  of shares of  the applicable  class next  determined
after  receipt of the  redemption request. The  redemption price may  be more or
less than the  purchase price. Certain  redemptions that cause  the value of  an
account  to remain for  a continuous 60-day period  below the minimum investment
amount for  Class A  shares or  for Class  B shares  may result  in  involuntary
redemption  or automatic conversion. For additional information on how to redeem
shares and  involuntary redemption  or conversion,  see "Purchase  of Shares  --
Minimum  Account Sizes and Involuntary Redemption  of Shares" and "Redemption of
Shares."
 
                                       8
<PAGE>
RISK FACTORS
 
   
    The  investment  policies  of  the   Portfolio  entail  certain  risks   and
considerations  of  which an  investor should  be  aware. Because  the Portfolio
invests primarily in the securities of companies principally engaged in the real
estate industry, its investments may be subject to the risks associated with the
direct ownership  of real  estate. The  Portfolio's share  price and  investment
return fluctuate, and a shareholder's investment when redeemed may be worth more
or  less than his original cost. Because  it is expected that the Portfolio will
invest a substantial  portion of  its assets  in real  estate investment  trusts
("REITs"),  the Portfolio may  also be subject to  certain risks associated with
the  direct  investments  of  REITs.   The  Portfolio  may  invest  in   certain
derivatives,   including  options,   futures  and  options   on  futures.  These
investments entail  certain costs  and  risks, including  imperfect  correlation
between  the value  of securities  held by  the Portfolio  and the  value of the
particular derivative  instrument, and  the risk  that the  Portfolio could  not
close  out a derivatives position  when it would be  most advantageous to do so.
Because the Portfolio is a non-diversified portfolio, the Portfolio will  invest
a  greater proportion  of its assets  in the  securities of a  smaller number of
issuers and, as a result, will be subject to a greater risk with respect to  its
portfolio  securities.  Each of  these  investment strategies  involves specific
risks which are described under "Investment Objectives and Policies" herein  and
under  "Investment  Objectives  and  Policies" in  the  Statement  of Additional
Information.
    
 
                                       9
<PAGE>
                       INVESTMENT OBJECTIVE AND POLICIES
 
   
    The investment  objective  of the  Portfolio  is to  provide  above  average
current  income  and long-term  capital appreciation  by investing  primarily in
equity securities  of companies  in  the U.S.  real estate  industry,  including
"REITs."  Equity securities include common stocks, shares or units of beneficial
interest of REITs, limited partnership interests in master limited partnerships,
rights or warrants to purchase common stocks, securities convertible into common
stocks,  and  preferred  stock.  The  Portfolio's  investment  objective  is   a
fundamental  policy which may not be changed  without the approval of a majority
of the Portfolio's outstanding voting securities. There is no assurance that the
Portfolio will  attain  its  objectives.  In addition  to  the  investments  and
strategies  described below, the Portfolio may  invest in certain securities and
obligations as  set  forth in  "Additional  Investment Information"  below.  The
investment  policies described  below are  not fundamental  policies and  may be
changed without shareholder approval.
    
 
    Under normal circumstances,  at least  65% of the  Portfolio's total  assets
will  be invested  in income  producing equity  securities of  U.S. and non-U.S.
companies principally engaged in the U.S. real estate industry. For purposes  of
the  Portfolio's investment policies, a company  is "principally engaged" in the
real estate industry if (i) it derives  at least 50% of its revenues or  profits
from  the ownership, construction, management, financing or sale of residential,
commercial or industrial real  estate or (ii)  it has at least  50% of the  fair
market  value of  its assets invested  in residential,  commercial or industrial
real estate. Companies  in the real  estate industry may  include among  others:
REITs, master limited partnerships that invest in interests in real estate, real
estate operating companies, and companies with substantial real estate holdings,
such  as  hotel companies,  residential  builders and  land-rich  companies. The
Portfolio seeks  to invest  in equity  securities of  companies that  provide  a
dividend   yield  that  exceeds  the  composite  dividend  yield  of  securities
comprising the Standard & Poor's 500 Stock Price Index ("S&P 500").
 
    A substantial portion of  the Portfolio's total assets  will be invested  in
securities  of REITs.  REITs pool investors'  funds for  investment primarily in
income producing real estate or real  estate related loans or interests. A  REIT
is  not taxed  on income  distributed to its  shareholders or  unitholders if it
complies with regulatory requirements  relating to its organization,  ownership,
assets  and income, and with a regulatory  requirement that it distribute to its
shareholders or unitholders at least 95% of its taxable income for each  taxable
year.  Generally, REITs  can be  classified as  Equity REITs,  Mortgage REITs or
Hybrid REITs. Equity REITs invest the majority of their assets directly in  real
property  and derive  their income primarily  from rents and  capital gains from
appreciation  realized  through  property   sales.  Equity  REITs  are   further
categorized  according to  the types of  real estate securities  they own, e.g.,
apartment properties, retail shopping centers, office and industrial properties,
hotels, health-care facilities, manufactured  housing and mixed-property  types.
Mortgage  REITs invest the majority of their assets in real estate mortgages and
derive their income primarily from  interest payments. Hybrid REITs combine  the
characteristics  of both  Equity and Mortgage  REITs. The  Portfolio will invest
primarily in Equity REITs. A shareholder in the Portfolio should realize that by
investing in REITs indirectly through the  Portfolio, he will bear not only  his
proportionate  share of the expenses of  the Portfolio, but also indirectly, the
management expenses of underlying REITs.
 
    Under normal circumstances, the Portfolio may invest up to 35% of its  total
assets  in  debt securities  issued or  guaranteed by  real estate  companies or
secured by real estate assets and rated, at time of purchase, in one of the four
highest  rating  categories  by  a  nationally  recognized  statistical   rating
organization  ("NRSRO") or determined by the Adviser to be of comparable quality
at the time of purchase, high quality money market
 
                                       10
<PAGE>
instruments, such  as notes,  certificates of  deposit or  bankers'  acceptances
issued by domestic or foreign insures, or high-grade debt securities, consisting
of corporate debt securities and United States Government securities. Securities
rated  in the  lowest category of  investment grade  securities have speculative
characteristics. Investment grade  securities are securities  that are rated  in
one of the four highest rating categories by an NRSRO.
 
    Any  remaining assets  not invested  as described  above may  be invested in
certain securities or obligations, including derivative securities, as set forth
in "Additional Investment Information" below.  The Portfolio may concentrate  in
the  U.S. real estate  industry, but may not  invest more than  25% of its total
assets in securities of companies in any one other industry (for these  purposes
the U.S. Government and its agencies and instrumentalities are not considered an
industry).
 
RISK FACTORS
 
    The   investment  policies  of  the   Portfolio  entail  certain  risks  and
considerations of  which an  investor  should be  aware. Because  the  Portfolio
invests primarily in the securities of companies principally engaged in the real
estate industry, its investments may be subject to the risks associated with the
direct  ownership of  real estate. These  risks include: the  cyclical nature of
real estate  values, risks  related to  general and  local economic  conditions,
overbuilding   and  increased  competition,  increases  in  property  taxes  and
operating expenses, demographic trends and variations in rental income,  changes
in zoning laws, casualty or condemnation losses, environmental risks, regulatory
limitations  on  rents, changes  in  neighborhood values,  related  party risks,
changes in the appeal of properties to tenants, increases in interest rates  and
other  real estate capital  market influences. Generally,  increases in interest
rates will increase the costs of  obtaining financing, which could directly  and
indirectly  decrease the value  of the Portfolio's  investments. The Portfolio's
share price and investment return fluctuate, and a shareholder's investment when
redeemed may be worth more or less than his original cost.
 
    Because it is expected that the Portfolio will invest a substantial  portion
of  its assets  in REITs, the  Portfolio will  also be subject  to certain risks
associated with  the direct  investments  of REITs.  REITs  may be  affected  by
changes in the value of their underlying properties and by defaults by borrowers
or  tenants.  Mortgage  REITs may  be  affected  by the  quality  of  the credit
extended. Furthermore,  REITs are  dependent on  specialized management  skills.
Some REITs may have limited diversification and may be subject to risks inherent
in  investments in a limited number of  properties, in a narrow geographic area,
or in  a  single property  type.  REITs depend  generally  on their  ability  to
generate cash flow to make distributions to shareholders or unitholders, and may
be  subject to defaults by borrowers  and to self-liquidations. In addition, the
performance of a REIT  may be affected  by its failure  to qualify for  tax-free
pass-through  of income under the Internal Revenue Code of 1986, as amended (the
"Code"), or  its  failure to  maintain  exemption from  registration  under  the
Investment  Company  Act  of  1940,  as amended  (the  "1940  Act").  Changes in
prevailing interest rates may inversely affect the value of the debt  securities
in which the Portfolio will invest. Changes in the value of portfolio securities
will  not necessarily affect cash income  derived from these securities but will
affect a Portfolio's net asset value.
 
    Because the Portfolio is a  non-diversified portfolio, the Portfolio is  not
limited  by the 1940 Act in the proportion of its assets that may be invested in
the obligations of  a single issuer.  Thus, the Portfolio  may invest a  greater
proportion  of its assets in the securities  of a smaller number of issuers and,
as a result, will  be subject to  a greater risk with  respect to its  portfolio
securities.  Any economic,  political, or regulatory  developments affecting the
value of the securities the Portfolio holds  could have a greater impact on  the
total value of the Portfolio's
 
                                       11
<PAGE>
   
holdings  than would be the case  if the Portfolio's securities were diversified
among  more  issuers.  The  Portfolio,  however,  intends  to  comply  with  the
diversification  requirements imposed by  the Internal Revenue  Code of 1986, as
amended (the "Code") for qualification as a regulated investment company.
    
 
                       ADDITIONAL INVESTMENT INFORMATION
 
   
    FUTURES CONTRACTS  AND OPTIONS  ON  FUTURES CONTRACTS.   The  Portfolio  may
purchase  and sell futures contracts and options on futures contracts, including
but not limited to financial futures, securities index futures, foreign currency
exchange futures, and interest rate futures contracts. Futures contracts provide
for the sale by one party and purchase by another party of a specified amount of
a specific security, instrument or basket thereof, at a specific future date and
at a specified price. An option on  a futures contract is a legal contract  that
gives  the  holder  the right  to  buy or  sell  a specified  amount  of futures
contracts at a fixed or determinable price upon the exercise of the option.
    
 
   
    The Portfolio may  sell securities  index futures  contracts and/or  options
thereon  in anticipation of or during a  market decline to attempt to offset the
decrease in market value of investments in its portfolio, or purchase securities
index futures in order to gain market exposure. Subject to applicable laws,  the
Portfolio  may engage in transactions in securities index futures contracts (and
options thereon)  which  are  traded  on  a  recognized  securities  or  futures
exchange,  or  may purchase  or sell  such  instruments in  the over-the-counter
market. There currently are limited securities index futures and options on such
futures in many countries,  particularly emerging countries.  The nature of  the
strategies  adopted by the Adviser, and the extent to which those strategies are
used, may depend on the development of such markets.
    
 
   
    The Portfolio may engage in transactions involving foreign currency exchange
futures contracts. Such contracts  involve an obligation to  purchase or sell  a
specific  currency at  a specified  future date  and at  a specified  price. The
Portfolio may engage in such transactions to hedge their respective holdings and
commitments against changes  in the level  of future currency  rates or to  gain
exposure to a particular currency.
    
 
   
    The   Portfolio  may  engage  in   transactions  in  interest  rate  futures
transactions. Interest rate futures contracts involve an obligation to  purchase
or  sell a specific debt  security, instrument or basket  thereof at a specified
future date at  a specified price.  The value  of the contract  rises and  falls
inversely  with  changes in  interest rates.  The Portfolio  may engage  in such
transactions to hedge their holdings of debt instruments against future  changes
in interest rates.
    
 
   
    Financial  futures are futures contracts  relating to financial instruments,
such as  U.S. Government  securities, foreign  currencies, and  certificates  of
deposit.  Such contracts  involve an obligation  to purchase or  sell a specific
security, instrument or basket thereof at a specified future date at a specified
price. Like  interest rate  futures contracts,  the value  of financial  futures
contracts  rises  and  falls  inversely  with  changes  in  interest  rates. The
Portfolio may engage in financial futures contracts for hedging and  non-hedging
purposes.
    
 
   
    Under  rules  adopted  by  the  Commodity  Futures  Trading  Commission, the
Portfolio may enter into futures contracts and options thereon for both  hedging
and  non-hedging purposes,  provided that  not more  than 5%  of the Portfolio's
total assets at the time of entering the transaction are required as margin  and
option   premiums  to  secure  obligations  under  such  contracts  relating  to
activities   that    do    not    constitute   "bona    fide"    hedging.    The
    
 
                                       12
<PAGE>
   
Portfolio  will  not  enter  into  futures  contracts  to  the  extent  that its
outstanding  obligations  to  purchase  securities  under  such  contracts,   in
combination   with  its   outstanding  obligations   with  respect   to  options
transactions (including  options to  purchase securities  or instruments)  would
exceed 20% of its total assets.
    
 
   
    Gains  and losses  on futures  contracts and  options thereon  depend on the
Adviser's ability  to  predict correctly  the  direction of  securities  prices,
interest  rates and other economic factors.  Other risks associated with the use
of futures  and options  are (i)  imperfect correlation  between the  change  in
market  value of investments held by the Portfolio and the prices of futures and
options relating to  investments purchased or  sold by the  Portfolio, and  (ii)
possible  lack  of a  liquid secondary  market  for a  futures contract  and the
resulting inability to  close a futures  position. The risk  that the  Portfolio
will  be unable  to close  out a  futures position  or options  contract will be
minimized by only entering  into futures contracts  or options transactions  for
which  there appears to  be a liquid  exchange or secondary  market. The risk of
loss in trading on futures contracts in some strategies can be substantial,  due
both  to  the low  margin deposits  required  and the  extremely high  degree of
leverage involved in futures pricing.
    
 
   
    LOANS OF PORTFOLIO SECURITIES.  The  Portfolio may lend their securities  to
brokers, dealers, domestic and foreign banks or other financial institutions for
the purpose of increasing its net investment income. These loans must be secured
continuously by cash or equivalent collateral, or by a letter of credit at least
equal  to the  market value  of the securities  loaned plus  accrued interest or
income. There may be a risk of delay in recovery of the securities or even  loss
of  rights  in  the  collateral  should  the  borrower  of  the  securities fail
financially. The  Portfolio will  not enter  into securities  loan  transactions
exceeding, in the aggregate, 33 1/3% of the market value of its total assets.
    
 
    MONEY  MARKET INSTRUMENTS.   The Portfolio  is permitted to  invest in money
market  instruments,  although  the  Portfolio  intends  to  stay  invested   in
securities  satisfying its primary investment objective to the extent practical.
The Portfolio  may make  money market  investments pending  other investment  or
settlement  for liquidity,  or in  adverse market  conditions. The  money market
investments  permitted  for  the  Portfolio  include  obligations  of  the  U.S.
Government  and  its  agencies  and  instrumentalities,  other  debt securities,
commercial paper,  bank  obligations  including, certificates  of  deposit,  and
repurchase agreements.
 
    NON-PUBLICLY   TRADED   SECURITIES,   PRIVATE   PLACEMENTS   AND  RESTRICTED
SECURITIES.  The Portfolio may invest in securities that are neither listed on a
stock exchange nor traded over-the-counter. Such unlisted equity securities  may
involve  a  higher degree  of business  and  financial risk  that can  result in
substantial losses. As a result  of the absence of  a public trading market  for
these  securities,  they may  be less  liquid  than publicly  traded securities.
Although these securities  may be resold  in privately negotiated  transactions,
the prices realized from these sales could be less than those originally paid by
the  Portfolio  or less  than  what may  be considered  the  fair value  of such
securities. Further, companies whose securities are not publicly traded may  not
be  subject to the  disclosure and other  investor protection requirements which
might be applicable if their securities were publicly traded. If such securities
are required  to  be  registered  under  the securities  laws  of  one  or  more
jurisdictions  before being  resold, the Portfolio  may be required  to bear the
expenses of registration.
 
   
    As a general matter, the Portfolio may  not invest more than 15% of its  net
assets  in  illiquid  securities, including  securities  for which  there  is no
readily available secondary market. Securities that are not registered under the
Securities Act of 1933, as amended (the "1933 Act"), but that can be offered and
sold to qualified institutional buyers under Rule 144A under the 1933 Act ("Rule
144A Securities") will not be included within
    
 
                                       13
<PAGE>
   
the foregoing 15% restriction if the securities are determined to be liquid. The
Board of Directors has adopted guidelines and delegated to the Adviser,  subject
to  the supervision of the Board of Directors, the daily function of determining
and monitoring the liquidity of Rule  144A Securities. Rule 144A Securities  may
become  illiquid  if  qualified  institutional  buyers  are  not  interested  in
acquiring the securities.
    
 
   
    OPTIONS TRANSACTIONS.  The Portfolio may seek to increase its return or  may
hedge  its portfolio  investments through  options transactions  with respect to
securities, instruments, indices or baskets  thereof in which the Portfolio  may
invest,  as well as  with respect to  foreign currency. Purchasing  a put option
gives the Portfolio the right to  sell a specified security, currency or  basket
of  securities or currencies at  the exercise price until  the expiration of the
option. Purchasing a  call option gives  the Portfolio the  right to purchase  a
specified  security,  currency  or basket  of  securities or  currencies  at the
exercise price  until  the expiration  of  the  option. The  Portfolio  may  not
purchase  call and  put options to  the extent  that the value  of its aggregate
investment in options exceeds 5% of its total assets.
    
 
   
    The  Portfolio  also  may  write  (i.e.,  sell)  put  and  call  options  on
investments  held in its portfolio, as well as with respect to foreign currency.
A Portfolio that has written an  option receives a premium, which increases  the
Portfolio's  return on  the underlying security  or instrument in  the event the
option expires unexercised or is closed out  at a profit. However, by writing  a
call option, the Portfolio will limit its opportunity to profit from an increase
in  the market value of the underlying security or instrument above the exercise
price of the option for as long  as the Portfolio's obligation as writer of  the
option  continues. The  Portfolio may only  write options that  are "covered." A
covered call option  means that so  long as  the Portfolio is  obligated as  the
writer  of the  option, it  will own (i)  the underlying  security or instrument
subject  to  the  option  or  (ii)  securities  or  instruments  convertible  or
exchangeable  without  the payment  of any  consideration  into the  security or
instrument subject to the option.
    
 
   
    By writing (or selling) a put option, the Portfolio incurs an obligation  to
buy  the security or instrument underlying the  option from the purchaser of the
put at the option's exercise price at any time during the option period, at  the
purchaser's election. Options written by the Portfolio may be exercisable by the
purchaser  only on a  specific date. A  Portfolio that has  written a put option
will earmark  or segregate  sufficient liquid  assets to  cover its  obligations
under the option.
    
 
   
    The  Portfolio may  engage in  transactions in  options which  are traded on
recognized exchanges or  over-the-counter. There currently  are limited  options
markets  in  many  countries,  particularly  emerging  countries  such  as Latin
American countries, and the nature of the strategies adopted by the Adviser  and
the  extent to which those strategies are used will depend on the development of
such option markets. The  primary risks associated with  the use of options  are
(i)  imperfect correlation  between the  change in  market value  of investments
held, purchased or sold by the Portfolio  and the prices of options relating  to
such  investments; and (ii)  possible lack of  a liquid secondary  market for an
option.
    
 
    REPURCHASE AGREEMENTS.  The Portfolio  may enter into repurchase  agreements
with  brokers, dealers or  banks that meet the  credit guidelines established by
the Fund's Board of Directors. In  a repurchase agreement, the Portfolio buys  a
security  from a seller  that has agreed  to repurchase it  at a mutually agreed
upon date and price, reflecting the interest rate effective for the term of  the
agreement.  The term of these agreements is  usually from overnight to one week,
and never  exceeds one  year. Repurchase  agreements may  be viewed  as a  fully
collateralized  loan  of money  by the  Portfolio to  the seller.  The Portfolio
always receives securities, with a market  value at least equal to the  purchase
price  (including accrued interest)  as collateral and  this value is maintained
 
                                       14
<PAGE>
during  the term  of the  agreement. If the  seller defaults  and the collateral
value declines, the Portfolio might incur a loss. If bankruptcy proceedings  are
commenced  with  respect to  the seller,  the  Portfolio's realization  upon the
collateral may  be  delayed  or  limited.  The  Portfolio  may  not  enter  into
repurchase  agreements with more  than seven days  to maturity if,  as a result,
more than 15% of the market value of the Portfolio's net assets are invested  in
these  agreements  and other  investments for  which  market quotations  are not
readily available or which are otherwise illiquid.
 
   
    TEMPORARY INVESTMENTS.  For temporary  defensive purposes, when the  Adviser
determines  that market conditions warrant, the  Portfolio may invest up to 100%
of its assets in dollar and non-dollar denominated money market instruments  and
short-  and medium-term debt securities that the  Adviser believes to be of high
quality, or hold cash. The short-  and medium-term debt securities in which  the
Portfolio  may invest consist of (a) obligations  of the U.S. or foreign country
governments, their respective agencies  or instrumentalities; (b) bank  deposits
and  bank  obligations (including  certificates  of deposit,  time  deposits and
bankers' acceptances)  of  U.S. or  foreign  country banks  denominated  in  any
currency;  (c) floating rate securities and other instruments denominated in any
currency issued by international development  agencies; (d) finance company  and
corporate  commercial paper and  other short-term corporate  debt obligations of
U.S. and foreign  country corporations  meeting the  Portfolio's credit  quality
standards;  and  (e) repurchase  agreements with  banks and  broker-dealers with
respect to such securities.
    
 
    WHEN-ISSUED AND DELAYED  DELIVERY SECURITIES.   The  Portfolio may  purchase
securities  on a  when-issued or delayed  delivery basis.  In such transactions,
instruments are bought with payment and  delivery taking place in the future  in
order  to secure what is considered to be  an advantageous yield or price at the
time of the transaction. Delivery of  and payment for these securities may  take
as  long as a month or more after  the date of the purchase commitment, but will
take place  no more  than 120  days after  the trade  date. The  Portfolio  will
maintain  with the Custodian  a separate account with  a segregated portfolio of
cash or liquid securities in an amount at least equal to these commitments.  The
payment  obligation and the interest rates that  will be received are each fixed
at the time the Portfolio enters into the commitment and no interest accrues  to
the  Portfolio until settlement. Thus,  it is possible that  the market value at
the time of settlement could be higher  or lower than the purchase price if  the
general  level of  interest rates  has changed.  It is  a current  policy of the
Portfolio not to enter into when-issued commitments exceeding, in the aggregate,
15% of the market value of  the Portfolio's total assets less liabilities  other
than the obligations created by these commitments.
 
                             INVESTMENT LIMITATIONS
 
   
    As a non-diversified investment company, the Portfolio is not limited by the
1940  Act in  the proportion  of its total  assets that  may be  invested in the
obligations of  a  single issuer.  Thus,  the  Portfolio may  invest  a  greater
proportion  of its total assets in the securities of a smaller number of issuers
and, as a result, will be subject to greater risk with respect to its  portfolio
securities.  However, the Portfolio  intends to comply  with the diversification
requirements imposed  by  the  Code for  qualification  a  regulated  investment
company.   See  "Investment   Limitations"  in   the  Statement   of  Additional
Information.
    
 
    The Portfolio operates under certain investment restrictions that are deemed
fundamental limitations and may be changed only with the approval of the holders
of a majority of the Portfolio's outstanding shares and
 
                                       15
<PAGE>
under certain non-fundamental investment limitations that may be changed without
shareholder  approval.   For   additional   information   on   fundamental   and
non-fundamental  limitations, see  "Investment Limitations" in  the Statement of
Additional Information.
 
                             MANAGEMENT OF THE FUND
 
   
    INVESTMENT ADVISER.  Morgan Stanley Asset Management Inc. is the Adviser and
Administrator of the Fund  and each portfolio.  The Adviser provides  investment
advice  and portfolio  management services,  pursuant to  an Investment Advisory
Agreement and, subject  to the  supervision of  the Fund's  Board of  Directors,
makes   the  Portfolio's  day-to-day  investment  decisions,  arranges  for  the
execution of  portfolio  transactions  and  generally  manages  the  Portfolio's
investments.  The  Adviser is  entitled  to receive  from  the U.S.  Real Estate
Portfolio an annual  management fee, payable  quarterly, equal to  0.80% of  the
average daily net assets of the Portfolio.
    
 
   
    The  fees of the  Portfolio are higher than  most investment companies', but
the Adviser believes the fee is comparable to those of investment companies with
similar investment policies. The Adviser has  agreed to a reduction in the  fees
payable  to it and to reimburse the  Portfolio, if necessary, if such fees would
cause the total annual  operating expenses of the  Portfolio to exceed 1.00%  of
the average daily net assets of the Class A shares of the Portfolio and 1.25% of
the average daily net assets of the Class B shares of the Portfolio.
    
 
   
    The  Adviser, with  principal offices  at 1221  Avenue of  the Americas, New
York, New York  10020, conducts  a worldwide portfolio  management business  and
provides  a broad  range of  portfolio management  services to  customers in the
United States and  abroad. On February  5, 1997, Morgan  Stanley Group Inc.  and
Dean  Witter, Discover & Co.  announced that they had  entered into an Agreement
and Plan of Merger to  form Morgan Stanley, Dean  Witter, Discover & Co.  Morgan
Stanley  Group Inc.  is the  direct parent  of the  Adviser and  Morgan Stanley.
Subject to certain conditions  being met, it is  currently anticipated that  the
transaction  will close in mid-1997. Thereafter,  the Adviser and Morgan Stanley
will be subsidiaries of Morgan Stanley, Dean Witter, Discover & Co. At March 31,
1997, the  Adviser, together  with its  affiliated asset  management  companies,
managed  investments totaling in excess of $118 billion, including approximately
$100 billion  under active  management and  $18 billion  as Named  Fiduciary  or
Fiduciary  Adviser. See "Management of the  Fund" in the Statement of Additional
Information.
    
 
    PORTFOLIO MANAGER. -- RUSSELL C. PLATT.  Mr. Platt joined Morgan Stanley  in
1982  and  currently is  a  Principal of  the  Firm. Russell  Platt  has primary
responsibility for managing the real  estate securities investment business  for
Morgan  Stanley  Asset  Management  ("MSAM")  and  serves  as  a  member  of the
Investment  Committee  of  The  Morgan  Stanley  Real  Estate  Fund   ("MSREF").
Previously,  Mr. Platt served as  a Director of MSREF,  where he was involved in
capital raising, acquisitions, oversight of investments and investor  relations.
MSREF is a privately held limited partnership engaged in the acquisition of real
estate  assets, portfolios and real estate operating companies with gross assets
of approximately $3.5 billion as of December 1994. From 1991 to 1993, Mr.  Platt
was   head  of  Morgan  Stanley's   Transaction  Development  Group,  which  was
responsible for identifying and structuring real estate investment opportunities
for the Firm and its clients  worldwide. As part of these responsibilities,  Mr.
Platt directed Morgan Stanley Realty's activities in Latin America and served as
U.S. liaison for Morgan Stanley Realty's Japanese real estate clients. From 1990
to  1991, Mr. Platt was based in Morgan Stanley Realty's London Office, where he
was responsible  for European  transaction development.  Prior to  this, he  had
extensive  transaction  responsibilities  involving  portfolio,  retail, office,
hotel and apartment sales and
 
                                       16
<PAGE>
financings. Mr. Platt  graduated from Williams  College in 1982  with a B.A.  in
Economics  and received  his M.B.A.  from Harvard  Business School  in 1986. Mr.
Platt is a member of the Board of Trustees of The National Multi Housing Council
and The Wharton Real  Estate Center, and  a member of  The Urban Land  Institute
(International  Council),  the National  Association  of Real  Estate Investment
Trusts and the Pension Real Estate Association.
 
    THEODORE R. BIGMAN.   Mr. Bigman joined Morgan  Stanley Asset Management  in
1995  as a Vice  President. Together with  Russell Platt, he  is responsible for
MSAM's real estate securities research. Prior to joining MSAM, he was a Director
at CS First Boston, where  he worked for eight years  in the Real Estate  Group.
Since  1992, Mr.  Bigman established  and managed  the REIT  effort at  CS First
Boston, including  primary responsibility  for $2.5  billion of  initial  public
offering  by real estate investment trusts. Previously, Mr. Bigman had extensive
real estate experience in a wide variety of transactions involving the financing
and sale of both individual assets and portfolios of real estate assets as  well
as  the  acquisition  and sale  of  several  real estate  companies.  Mr. Bigman
graduated from Brandeis University in 1983 with a B.A. in Economics and received
his M.B.A. from  Harvard University  in 1987.  He is  a member  of the  National
Association  of  Real  Estate  Investment Trusts  and  International  Council of
Shopping Centers.
 
    ADMINISTRATOR.  The  Adviser also  provides administrative  services to  the
Fund  pursuant to an  Administration Agreement. The  services provided under the
Administration Agreement are subject to the supervision of the Officers and  the
Board  of Directors of the Fund and include day-to-day administration of matters
related to the  corporate existence  of the  Fund, maintenance  of its  records,
preparation  of  reports,  supervision  of  the  Fund's  arrangements  with  its
custodian,  and  assistance  in  the  preparation  of  the  Fund's  registration
statements  under federal laws. The  Administration Agreement also provides that
the Administrator,  through its  agents, will  provide dividend  disbursing  and
transfer  agent services to the Fund.  For its services under the Administration
Agreement, the Fund  pays the Adviser  a monthly  fee which on  an annual  basis
equals 0.15% of the average daily net assets of the Portfolio.
 
   
    Under  an  agreement  between  the Adviser  and  The  Chase  Manhattan Bank.
("Chase"), Chase provides  certain administrative services  to the Fund  through
its  corporate  affiliate, Chase  Global Funds  Services Company  ("CGFSC"). The
Adviser supervises and monitors such administrative services provided by  CGFSC.
Their  services are also subject to the supervision of the Board of Directors of
the Fund. CGFSC's business address  is 73 Tremont Street, Boston,  Massachusetts
02108-3913.
    
 
    DIRECTORS  AND OFFICERS.  Pursuant to  the Fund's Articles of Incorporation,
the Board of Directors  decides upon matters of  general policy and reviews  the
actions  of  the Fund's  Adviser, Administrator,  Distributor and  other service
providers. The Officers  of the Fund  conduct and supervise  its daily  business
operations.
 
    DISTRIBUTOR.   Morgan  Stanley serves  as the  exclusive Distributor  of the
shares of  the Fund.  Under its  Distribution Agreement  with the  Fund,  Morgan
Stanley sells shares of the Portfolio upon the terms and at the current offering
price  described in this Prospectus. Morgan Stanley is not obligated to sell any
certain number of shares of the Portfolio.
 
    The Portfolio currently offers  only the classes of  shares offered by  this
Prospectus.  The Portfolio may in the future offer one or more classes of shares
with features, distribution expenses or  other expenses that are different  from
those of the classes currently offered.
 
                                       17
<PAGE>
    The  Fund has  adopted a Plan  of Distribution  with respect to  the Class B
shares of the Portfolio pursuant to Rule 12b-1 under the 1940 Act (the  "Plan").
Under  the Plan,  the Distributor  is entitled to  receive from  the Portfolio a
distribution fee, which  is accrued daily  and paid quarterly,  of 0.25% of  the
Class B shares' average daily net assets on an annualized basis. The Distributor
expects  to reallocate  most of its  fee to its  investment representatives. The
Distributor may, in its discretion, voluntarily  waive from time to time all  or
any  portion of its distribution fee and each of the Distributor and the Adviser
is free to make additional payments out of its own assets to promote the sale of
Fund shares,  including  payments  that compensate  financial  institutions  for
distribution services or shareholder services.
 
    The  Plan is designed to compensate the Distributor for its services, not to
reimburse the Distributor for its expenses,  and the Distributor may retain  any
portion  of the fee that it does not expend in fulfillment of its obligations to
the Fund.
 
    EXPENSES.  The Portfolio  is responsible for payment  of certain other  fees
and  expenses  (including legal  fees,  accountant's fees,  custodial  fees, and
printing and mailing  costs) specified  in the  Administration and  Distribution
Agreements.
 
                               PURCHASE OF SHARES
 
    Class  A and  Class B shares  of the Portfolio  may be purchased  at the net
asset value per share next determined after receipt of the purchase order by the
Portfolio. See "Valuation of Shares."
 
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
 
    For a  Portfolio  account  opened  on  or after  January  2,  1996  (a  "New
Account"),  the minimum initial investment and minimum account size are $500,000
for Class A shares and  $100,000 for Class B  shares. Certain advisory or  asset
allocation  accounts, such as Total Funds Management accounts, managed by Morgan
Stanley or  its  affiliates,  including the  Adviser  ("Managed  Accounts")  may
purchase  Class A shares without being subject to any minimum initial investment
or minimum account size requirements for  a Portfolio account. Employees of  the
Adviser  and certain of  its affiliates may  purchase Class A  Shares subject to
conditions,  including  a  lower  minimum  initial  investment,  established  by
Officers of the Fund.
 
    If  the  value of  a  New Account,  containing  Class A  shares  falls below
$500,000  (but   remains  at   or  above   $100,000)  because   of   shareholder
redemption(s),  the Fund will  notify the shareholder, and  if the account value
remains below  $500,000 (but  remains at  or above  $100,000) for  a  continuous
60-day period, the Class A shares in such account will convert to Class B shares
and will be subject to the distribution fee and other features applicable to the
Class  B shares. The Fund,  however, will not convert Class  A shares to Class B
shares based solely upon changes in the  market that reduce the net asset  value
of  shares. Under current tax  law, conversions between share  classes are not a
taxable event to the shareholder.
 
    Shares in a Portfolio account opened  prior to January 2, 1996 (a  "Pre-1996
Account")  were  designated Class  A  shares on  January  2, 1996.  Shares  in a
Pre-1996 Account  with  a  value  of  $100,000 or  more  on  March  1,  1996  (a
"Grandfathered  Class A Account") remained Class  A shares regardless of account
size thereafter. Except for  shares in a Managed  Account, shares in a  Pre-1996
Account  with a value of  less than $100,000 on  March 1, 1996 (a "Grandfathered
Class B account") converted  to Class B shares  on March 1, 1996.  Grandfathered
Class A Accounts and Managed Accounts are not subject to conversion from Class A
shares to Class B shares.
 
                                       18
<PAGE>
    Investors  may also invest in the Fund  by purchasing shares through a trust
department, broker, dealer, agent, financial planner, financial services firm or
investment adviser.  An  investor  may  be  charged  an  additional  service  or
transaction fee by that institution.
 
   
    The minimum investment levels may be waived at the discretion of the Adviser
for  (i) certain employees and customers of Morgan Stanley or its affiliates and
certain  trust  departments,  brokers,  dealers,  agents,  financial   planners,
financial  services  firms, or  investment advisers  that  have entered  into an
agreement with  Morgan  Stanley  or  its affiliates;  and  (ii)  retirement  and
deferred  compensation plans and trusts used  to fund such plans, including, but
not limited to, those defined in Section  401(a), 403(b) or 457 of the Code  and
"rabbi  trusts".  The  Fund  reserves  the  right  to  modify  or  terminate the
conversion features  of the  shares as  stated above  at any  time upon  60-days
notice to shareholders.
    
 
    The  Adviser reserves the right in its sole discretion to determine which of
such advisory  or  asset allocation  accounts  shall be  Managed  Accounts.  For
information  regarding  Managed  Accounts, please  contact  your  Morgan Stanley
account representative or the Fund at the telephone number provided on the cover
of this Prospectus.
 
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
 
    If the value of  a New Account falls  below $100,000 because of  shareholder
redemption(s),  the Fund will  notify the shareholder, and  if the account value
remains below  $100,000 for  a  continuous 60-day  period,  the shares  in  such
account  are subject to redemption  by the Fund and,  if redeemed, the net asset
value of  such  shares will  be  promptly paid  to  the shareholder.  The  Fund,
however,  will not redeem  shares based solely  upon changes in  the market that
reduce the net asset value of shares.
 
    Grandfathered Class A Accounts, Grandfathered  Class B Accounts and  Managed
Accounts  are not subject to involuntary redemption. The Fund reserves the right
to modify or  terminate the  involuntary redemption  features of  the shares  as
stated above at any time upon 60-days notice to shareholders.
 
CONVERSION FROM CLASS B TO CLASS A SHARES
 
    If the value of Class B shares in a Portfolio account increases, whether due
to  shareholder share  purchases or  market activity,  to $500,000  or more, the
Class B shares  will convert  to Class  A shares.  Under current  tax law,  such
conversion  is not a taxable event to  the shareholder. Class A shares converted
from Class B shares  are subject to the  same minimum account size  requirements
that  are applicable to New Accounts containing Class A shares, as stated above.
The Fund reserves the  right to modify or  terminate this conversion feature  at
any time upon 60-days notice to shareholders.
 
INITIAL PURCHASES DIRECTLY FROM THE FUND
 
    The  Fund's determination of an investor's eligibility to purchase shares of
a given class  will take precedence  over the investor's  selection of a  class.
Assuming  the investor is eligible for the  class, the Fund will select the most
favorable class for the investor, if the investor has not done so.
 
                                       19
<PAGE>
1) BY CHECK.   An account may  be opened  by completing and  signing an  Account
   Registration Form and mailing it, together with a check ($500,000 minimum for
   Class  A  shares of  the Portfolio  and $100,000  for Class  B shares  of the
   Portfolio, with certain  exceptions for Morgan  Stanley employees and  select
   customers)  payable to "Morgan Stanley Institutional Fund, Inc. -- [portfolio
   name]", to:
 
      Morgan Stanley Institutional Fund, Inc.
      P.O. Box 2798
      Boston, Massachusetts 02208-2798
 
   
  Payment will  be accepted  only in  U.S. dollars,  unless prior  approval  for
  payment  by other currencies is given by  the Fund. The class(es) of shares of
  the Portfolio to be purchased should be designated on the Account Registration
  Form. For purchases  by check, the  Fund is ordinarily  credited with  Federal
  Funds  within one  business day.  Thus, your  purchase of  shares by  check is
  ordinarily credited to your account  at the net asset  value per share of  the
  relevant Portfolio determined on the next business day after receipt.
    
 
2) BY  FEDERAL  FUNDS WIRE.   Purchases  may be  made by  having your  bank wire
   Federal Funds to the Fund's bank  account. In order to ensure prompt  receipt
   of your Federal Funds Wire, it is important that you follow these steps:
 
A.   Telephone  the Fund  (toll free: 1-800-548-7786)  and provide  us with your
    name, address,  telephone  number,  Social Security  or  Tax  Identification
    Number,  the  portfolio(s) selected,  the class  selected, the  amount being
    wired, and by  which bank.  We will  then provide  you with  a Fund  account
    number.  (Investors with existing accounts should also notify the Fund prior
    to wiring funds.)
 
B.   Instruct  your  bank to  wire  the  specified amount  to  the  Fund's  Wire
    Concentration  Bank Account (be sure  to have your bank  include the name of
    the portfolio(s)  selected,  the  class selected,  and  the  account  number
    assigned to you) as follows:
 
   
    The Chase Manhattan Bank
    One Manhattan Plaza
    New York, NY 10081-1000
    ABA #021000021
    DDA #910-2-733293
    Attn: Morgan Stanley Institutional Fund, Inc.
    Ref: (Portfolio name, your account number, your account name)
    
 
    Please call the Fund at 1-800-548-7786 prior to wiring funds.
 
C.   Complete and sign the Account Registration  Form and mail it to the address
    shown thereon.
 
  The purchase price of the Class A and  Class B shares of the Portfolio is  the
  net asset value next determined after the order is received. See "Valuation of
  Shares."  An order received prior  to the regular close  of the New York Stock
  Exchange ("NYSE"), which is currently 4:00 p.m. Eastern Time, will be executed
  at the price  computed on the  date of  receipt; an order  received after  the
  regular  close of the NYSE will be executed  at the price computed on the next
  day the NYSE is open as long  as the Transfer Agent receives payment by  check
  or in Federal Funds prior to the regular close of the NYSE on such day.
 
                                       20
<PAGE>
  Federal Funds purchase orders will be accepted only on a day on which the Fund
  and Chase (the "Custodian Bank") are open for business. Your bank may charge a
  service fee for wiring Federal Funds.
 
3) BY  BANK WIRE.   The  same procedure outlined  under "By  Federal Funds Wire"
   above must be  followed in  purchasing shares  by bank  wire. However,  money
   transferred  by bank wire may or may  not be converted into Federal Funds the
   same day, depending on the time the  money is received and the bank  handling
   the  wire. Prior to such conversion, an investor's money will not be invested
   and, therefore, will not be earning dividends. Your bank may charge a service
   fee for wiring funds.
 
ADDITIONAL INVESTMENTS
 
    You may  add to  your account  at any  time (minimum  additional  investment
$1,000,  except  for  automatic  reinvestment  of  dividends  and  capital gains
distributions for which there are no minimums) by purchasing shares at net asset
value by mailing a check to  the Fund (payable to "Morgan Stanley  Institutional
Fund, Inc. -- [portfolio name]") at the above address or by wiring monies to the
Custodian  Bank as outlined above. It is  very important that your account name,
the portfolio name and the class selected be specified in the letter or wire  to
assure  proper crediting  to your  account. In  order to  ensure that  your wire
orders are invested  promptly, you  are requested to  notify one  of the  Fund's
representatives  (toll free: 1-800-548-7786) prior  to the wire date. Additional
investments will be applied to purchase additional shares in the same class held
by a shareholder in a Portfolio account.
 
OTHER PURCHASE INFORMATION
 
    Although the legal rights of Class A  and Class B shares will be  identical,
the  different expenses borne by  each class will result  in different net asset
values and dividends. The net  asset value of Class  B shares will generally  be
lower than the net asset value of Class A shares as a result of the distribution
expense  charged to Class B shares. It  is expected, however, that the net asset
value per share of the two classes  will tend to converge immediately after  the
recording  of dividends  which will  differ by  approximately the  amount of the
distribution expense accrual differential between the classes.
 
   
    In the interest  of economy and  convenience, and because  of the  operating
procedures  of the Fund, certificates representing  shares of the Portfolio will
not be issued. All shares  purchased are confirmed to  you and credited to  your
account  on the Fund's books  maintained by the Adviser  or its agents. You will
have  the  same  rights  and  ownership  with  respect  to  such  shares  as  if
certificates had been issued.
    
 
    To  ensure that checks are collected by the Fund, withdrawals of investments
made by check  are not presently  permitted until payment  for the purchase  has
been  received,  which may  take up  to eight  business days  after the  date of
purchase. As a condition  of this offering,  if a purchase  is cancelled due  to
nonpayment or because your check does not clear, you will be responsible for any
loss  the Fund or its  agents incur. If you are  already a shareholder, the Fund
may redeem shares from your account(s) to  reimburse the Fund or its agents  for
any  loss. In addition, you  may be prohibited or  restricted from making future
investments in the Fund.
 
    Investors may  also invest  in the  Fund by  purchasing shares  through  the
Distributor.
 
EXCESSIVE TRADING
 
   
    Frequent   trades  involving  either  substantial   portfolio  assets  or  a
substantial portion of your  account or accounts controlled  by you can  disrupt
management  of  the  Portfolio  and raise  its  expenses.  Consequently,  in the
interest  of  all  the  stockholders  of  the  Portfolio  and  the   Portfolio's
performance, the Fund may in its discretion bar
    
 
                                       21
<PAGE>
   
a  stockholder that  engages in excessive  trading of  shares of any  class of a
portfolio from further purchases of shares of the Fund for an indefinite period.
The Fund  considers excessive  trading to  be more  than one  purchase and  sale
involving shares of the same class of a portfolio of the Fund within any 120-day
period.  As an example, exchanging  shares of portfolios of  the Fund as follows
amounts to excessive  trading: exchanging shares  of Portfolio A  for shares  of
Portfolio B, then exchanging shares of Portfolio B for shares of Portfolio C and
again  exchanging  shares of  Portfolio C  for  shares of  Portfolio B  within a
120-day period.  Two  types of  transactions  are exempt  from  these  excessive
trading  restrictions: (1)  trades exclusively between  money market portfolios;
and (2) trades done in connection with an asset allocation service, such as  TFM
Account  or  accounts  managed or  advised  by  the Adviser  and/or  any  of its
affiliates.
    
 
INVESTMENT IN FUNDS THROUGH A TOTAL FUNDS MANAGEMENT ("TFM") ACCOUNT
 
   
    In addition to the considerable diversification among individual  securities
you  receive by investing in a particular Portfolio, you can further reduce risk
by spreading  your assets  among  several different  Portfolios that  each  have
different   risk  and  return  characteristics.  TFM  is  an  active  investment
management service managed by Morgan Stanley or its affiliates, including Morgan
Stanley Asset  Management Inc.  (each,  a "TFM  Adviser"), that  allocates  your
investments  across a combination of either Class A or Class B shares of certain
of the Portfolios selected to meet your long-term investment objectives as  well
as, in certain circumstances, your current income objectives.
    
 
   
    The TFM Adviser has developed investment strategies for TFM Accounts to meet
the  diverse financial needs of different investors.  You can open a TFM Account
by meeting with one  of the investment professionals  of a Participating  Dealer
who  will review your situation and  help you identify your long-term investment
and/or current income  objectives. After  using TFM criteria  to determine  your
long-term  investment and/or  current income objectives,  you can  choose one of
several TFM investment strategies. Based  on your chosen strategy, your  initial
investment  will be allocated among a number of the Class A or Class B shares of
the Portfolios. Depending  on market  conditions, the  TFM Adviser  periodically
reallocates  the combination of Portfolios or the percentage amounts invested in
the shares  of each  Portfolio to  implement your  TFM investment  strategy.  In
addition,  your TFM Account will be periodically rebalanced to maintain your TFM
strategy's current asset allocation mix, if  and when the performance of one  or
more  of the  Portfolios unbalances  the strategy's  mix. You  will pay  the TFM
Adviser a fee for the  TFM Account service that is  in addition to and  separate
from the fees and expenses you will pay directly or indirectly as an investor in
the Portfolios. See "Fund Expenses."
    
 
    From  time to time, one or more of the Portfolios used for investment by the
TFM Accounts may experience relatively  large investments or redemptions due  to
the  TFM Account  allocations or  rebalancings recommended  by the  TFM Adviser.
These transactions will affect the Portfolios, since Portfolios that  experience
redemptions  as  a result  of  reallocations or  rebalancings  may have  to sell
portfolio securities and Portfolios  that receive additional  cash will have  to
invest  it in additional portfolio securities. While it is impossible to predict
the overall  impact of  these transactions  over time,  there could  be  adverse
effects on portfolio management to the extent that Portfolios may be required to
sell  securities or invest  cash at times  when they would  not otherwise do so.
These transactions  could also  have  tax consequences  if sales  of  securities
resulted  in  gains  and could  also  increase transaction  costs.  The Adviser,
representing the interests  of the  Portfolios, is committed  to minimizing  the
impact of TFM Account transactions on the Portfolios. The Adviser, however, will
have  a conflict in fulfilling  this responsibility in that  it also serves as a
TFM Adviser. In that  capacity, the Adviser, representing  the interests of  the
TFM  Accounts,  also  is  committed  to minimizing  the  impact  of  TFM Account
transactions on the Portfolios to
 
                                       22
<PAGE>
   
the extent  consistent  with  pursuing  the investment  objectives  of  the  TFM
Accounts.  In  addition, an  affiliate of  the TFM  Adviser, the  Distributor is
compensated on the sale, and may be compensated for distribution or  shareholder
services  on the sale of shares of  the Portfolios. See "Purchase of Shares" and
"Shareholder Services -- Exchange Features." The Adviser will monitor the impact
of TFM Account transactions on the Portfolios.
    
 
                              REDEMPTION OF SHARES
 
    You may  withdraw all  or  any portion  of the  amount  in your  account  by
redeeming  shares at any time. Please note  that purchases made by check are not
permitted to be redeemed until payment of the purchase price has been collected,
which may take up to  eight business days after  purchase. The Fund will  redeem
Class  A shares or  Class B shares of  the Portfolio at  the next determined net
asset value of shares of  the applicable class. On days  that both the NYSE  and
the  Custodian Bank are open for business, the  net asset value per share of the
Portfolio is determined at the regular  close of trading of the NYSE  (currently
4:00  p.m. Eastern  time). Shares of  the Portfolio  may be redeemed  by mail or
telephone. No charge is made for redemption. Any redemption may be more or  less
than  the purchase price of  your shares depending on,  among other factors, the
market value of the investment securities held by the Portfolio.
 
BY MAIL
 
    The Portfolio will redeem  its Class A  or Class B shares  at the net  asset
value determined on the date the request is received, if the request is received
in  "good order" before  the regular close  of the NYSE.  Your request should be
addressed to Morgan  Stanley Institutional  Fund, Inc., P.O.  Box 2798,  Boston,
Massachusetts  02208-2798, except that deliveries by overnight courier should be
addressed to Morgan  Stanley Institutional  Fund, Inc., c/o  Chase Global  Funds
Services Company, 73 Tremont Street, Boston, Massachusetts 02108-3913.
 
    "Good  order"  means that  the  request to  redeem  shares must  include the
following documentation:
 
        (a)  A letter of instruction or a stock assignment specifying the  class
    and  number  of  shares or  dollar  amount  to be  redeemed,  signed  by all
    registered owners  of  the shares  in  the exact  names  in which  they  are
    registered;
 
        (b)   Any  required   signature  guarantees   (see  "Further  Redemption
    Information" below); and
 
        (c)   Other supporting  legal documents,  if required,  in the  case  of
    estates,  trusts, guardianships,  custodianships, corporations,  pension and
    profit sharing plans and other organizations.
 
    Shareholders who are uncertain of requirements for redemption should consult
with a Fund representative.
 
BY TELEPHONE
 
    Provided you have previously elected the Telephone Redemption Option on  the
Account  Registration  Form, you  can  request a  redemption  of your  shares by
calling the Fund  and requesting  the redemption proceeds  be mailed  to you  or
wired to your bank. Please contact one of the Fund's representatives for further
details.  In times of drastic market conditions, the telephone redemption option
may be  difficult  to  implement.  If you  experience  difficulty  in  making  a
telephone  redemption, your request may be made  by regular mail or express mail
and it will be implemented  at the net asset value  next determined after it  is
received.  Redemption requests  sent to  the Fund  through express  mail must be
mailed   to   the   address   of   the   Dividend   Disbursing   and    Transfer
 
                                       23
<PAGE>
Agent listed under "General Information." The Fund and the Fund's transfer agent
(the  "Transfer Agent")  will employ reasonable  procedures to  confirm that the
instructions communicated  by telephone  are genuine.  These procedures  include
requiring the investor to provide certain personal identification information at
the  time an account is opened and prior to effecting each transaction requested
by telephone. In addition, all  telephone transaction requests will be  recorded
and   investors  may  be  required  to  provide  additional  telecopied  written
instructions regarding transaction requests. Neither  the Fund nor the  Transfer
Agent will be responsible for any loss, liability, cost or expense for following
instructions received by telephone that either of them reasonably believes to be
genuine.
 
    To  change the commercial  bank or account  designated to receive redemption
proceeds, a written  request must  be sent  to the  Fund at  the address  above.
Requests  to change the bank  or account must be  signed by each shareholder and
each signature must be guaranteed.
 
FURTHER REDEMPTION INFORMATION
 
    Normally the  Fund will  make payment  for all  shares redeemed  within  one
business  day of receipt  of the request, but  in no event  will payment be made
more than  seven days  after receipt  of  a redemption  request in  good  order.
However,  payments to investors  redeeming shares which  were purchased by check
will not be made until  payment for the purchase  has been collected, which  may
take up to eight days after the date of purchase. The Fund may suspend the right
of  redemption or postpone the date upon which redemptions are effected at times
when the NYSE is closed, or  under any emergency circumstances as determined  by
the Securities and Exchange Commission (the "Commission").
 
    If  the Board of  Directors determines that  it would be  detrimental to the
best interests of the  remaining shareholders of the  Portfolio to make  payment
wholly  or partly in cash, the Fund may  pay the redemption proceeds in whole or
in part by a distribution in-kind of securities held by the Portfolio in lieu of
cash   in    conformity   with    applicable    rules   of    the    Commission.
Distributions-in-kind  will be made in  readily marketable securities. Investors
may incur brokerage charges on the  sale of portfolio securities so received  in
payment of redemptions.
 
    To  protect  your account,  the Fund  and its  agents from  fraud, signature
guarantees are required for  certain redemptions to verify  the identity of  the
person  who has  authorized a redemption  from your account.  Please contact the
Fund for further information.
 
                              SHAREHOLDER SERVICES
 
EXCHANGE FEATURES
 
   
    You may exchange  shares that you  own in  the Portfolio for  shares of  any
other  available portfolio(s) of  the Fund (other  than the International Equity
Portfolio, which is  closed to  new investors). In  exchanging for  shares of  a
portfolio  with more  than one  class, the  class of  shares you  receive in the
exchange will be determined in the same  manner as any other purchase of  shares
and  will not  be based  on the  class of  shares surrendered  for the exchange.
Consequently, the same minimum initial  investment and minimum account size  for
determining  the  class  of shares  received  in  the exchange  will  apply. See
"Purchase of  Shares." Shares  of the  portfolios may  be exchanged  by mail  or
telephone.  The privilege to exchange shares  by telephone is automatic and made
available without shareholder election. Before you make an exchange, you  should
read the prospectus of the portfolio(s) in
    
 
                                       24
<PAGE>
which  you  seek to  invest. Because  an  exchange transaction  is treated  as a
redemption followed by  a purchase, an  exchange would be  considered a  taxable
event for shareholders subject to tax. The exchange privilege may be modified or
terminated by the Fund at any time upon 60-days notice to shareholders.
 
BY MAIL
 
    In  order to  exchange shares  by mail, you  should include  in the exchange
request the name, class of shares and account number of your current  Portfolio,
the name(s) of the portfolio(s) and class(es) of shares into which you intend to
exchange  shares, and the signatures of all registered account holders. Send the
exchange request to Morgan  Stanley Institutional Fund,  P.O. Box 2798,  Boston,
Massachusetts 02208-2798.
 
BY TELEPHONE
 
    When  exchanging shares by  telephone, have ready the  name, class of shares
and account number of the current  portfolio, the names of the portfolio(s)  and
class(es)  of  shares into  which  you intend  to  exchange shares,  your Social
Security number  or Tax  I.D. number,  and your  account address.  Requests  for
telephone  exchanges received prior to 4:00 p.m. (Eastern Time) are processed at
the close  of business  that  same day  based  on the  net  asset value  of  the
class(es)  of the portfolios involved in the exchange of the shares at the close
of business. Requests received after 4:00 p.m. (Eastern Time) are processed  the
next  business  day based  on the  net asset  value determined  at the  close of
business on such  day. For additional  information regarding responsibility  for
the  authenticity of  telephoned instructions, see  "Redemption of  Shares -- By
Telephone" above.
 
TRANSFER OF REGISTRATION
 
    You may transfer the registration of any of your Portfolio shares to another
person by writing  to Morgan Stanley  Institutional Fund, Inc.,  P.O. Box  2798,
Boston,  Massachusetts 02208-2798.  As in the  case of  redemptions, the written
request must  be  received  in good  order  before  any transfer  can  be  made.
Transferring  the  registration of  shares may  affect  the eligibility  of your
account for  a  given  class  of  the  Portfolio's  shares  and  may  result  in
involuntary  conversion or redemption  of your shares.  See "Purchase of Shares"
above.
 
                              VALUATION OF SHARES
 
   
    The net asset  value per  share of  a class of  shares of  the Portfolio  is
determined by dividing the total market value of the Portfolio's investments and
other  assets attributable to  such class, less  any liabilities attributable to
such class, by  the total  number of  outstanding shares  of such  class of  the
Portfolio.  Net  asset value  is  calculated separately  for  each class  of the
Portfolio. Net asset value per  share is determined as  of the regular close  of
the  NYSE on each day  that the NYSE is open  for business. Price information on
listed securities is  taken from the  exchange where the  security is  primarily
traded.  Securities  listed  on  a U.S.  securities  exchange  for  which market
quotations are available are valued at the last quoted sale price on the day the
valuation is made. Securities listed on  a foreign exchange are valued at  their
closing  price.  Unlisted securities  and listed  securities  not traded  on the
valuation date for which market quotations are readily available are valued at a
price within a range  not exceeding the  current asked price  nor less than  the
current  bid price. The current bid and asked prices are determined based on the
average of the bid and asked prices  quoted on such valuation date by  reputable
brokers.
    
 
    Bonds and other fixed income securities are valued according to the broadest
and  most representative market,  which will ordinarily  be the over-the-counter
market. Net asset value includes interest  on fixed income securities, which  is
accrued  daily.  In addition,  bonds and  other fixed  income securities  may be
valued on the
 
                                       25
<PAGE>
basis of prices provided by a pricing  service when such prices are believed  to
reflect  the fair  market value  of such  securities. The  prices provided  by a
pricing service are determined  without regard to bid  or last sale prices,  but
take  into account institutional-size,  trading in similar  groups of securities
and any developments related to  the specific securities. Securities not  priced
in  this  manner are  valued  at the  most recently  quoted  bid price  or, when
securities exchange valuations are used, at the latest quoted sale price on  the
day of valuation. If there is no such reported sale, the latest quoted bid price
will  be used. Securities purchased with remaining maturities of 60 days or less
are valued at amortized cost, if it approximates market value. In the event that
amortized cost does not  approximate market value,  market prices as  determined
above will be used.
 
   
    The  value  of other  assets  and securities  for  which quotations  are not
readily available  (including restricted  and unlisted  foreign securities)  and
those  securities  for which  it  is inappropriate  to  determine the  prices in
accordance with the above-stated procedures are determined in good faith at fair
value using  methods determined  by  the Board  of  Directors. For  purposes  of
calculating  net asset  value per  share, all  assets and  liabilities initially
expressed in foreign currencies will be translated into U.S. dollars at the mean
of the bid  and asked price  for such  currencies against the  U.S. dollar  last
quoted by any major bank.
    
 
    Although  the legal rights of Class A  and Class B shares will be identical,
the different expenses borne  by each class will  result in different net  asset
values  and dividends for the class.  Dividends will differ by approximately the
amount of the distribution expense  accrual differential among the classes.  The
net  asset value of  Class B shares will  generally be lower  than the net asset
value of the Class A shares as  a result of the distribution expense charged  to
Class B shares.
 
                            PERFORMANCE INFORMATION
 
    The  Fund may from time to time advertise total return for each class of the
Portfolio. THESE FIGURES ARE BASED ON  HISTORICAL EARNINGS AND ARE NOT  INTENDED
TO INDICATE FUTURE PERFORMANCE.
 
    The portfolio may advertise "total return" which shows what an investment in
a class of the Portfolio would have earned over a specified period of time (such
as one, five or ten years), assuming that all distributions and dividends by the
Portfolio were reinvested in the same class on the reinvestment dates during the
period.  Total return  does not  take into account  any federal  or state income
taxes that may be payable on  dividends and distributions or on redemption.  The
Fund  may  also include  comparative performance  information in  advertising or
marketing  the  Portfolio's  shares,  including  data  from  Lipper   Analytical
Services,  Inc.,  other  industry  publications,  business  periodicals,  rating
services and market indices.
 
    The performance figures  for Class  B shares  will generally  be lower  than
those  for Class  A shares because  of the  distribution fee charged  to Class B
shares.
 
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
 
    All income dividends and capital gains  distributions for a class of  shares
will be automatically reinvested in additional shares at net asset value, except
that,  upon written notice to the Fund or by checking off the appropriate box in
the Distribution Option Section on the Account Registration Form, a  shareholder
may elect to receive income dividends and capital gains distributions in cash.
 
                                       26
<PAGE>
   
    The  Portfolio expects  to distribute substantially  all of  its taxable net
investment income in the form of quarterly dividends. Net realized capital gains
for  the  Portfolio,  if  any,  after  reduction  for  any  available  tax  loss
carryforwards will also be distributed annually.
    
 
    Undistributed  net  investment income  is  included in  the  Portfolio's net
assets for the purpose of calculating  net asset value per share. Therefore,  on
the  "ex-dividend" date,  the net  asset value  per share  excludes the dividend
(i.e., is  reduced by  the per  share amount  of the  dividend). Dividends  paid
shortly after the purchase of shares by an investor, although in effect a return
of capital, are taxable to shareholders subject to income tax.
 
    Because  of  the  distribution  fee  and  any  other  expenses  that  may be
attributable to  the Class  B shares,  the net  income attributable  to and  the
dividends  payable  on  Class  B  shares  will  be  lower  than  the  net income
attributable to and the dividends  payable on Class A  shares. As a result,  the
net  asset value per share of the classes of the Portfolio will differ at times.
Expenses of the  Portfolio allocated  to a particular  class of  shares will  be
borne on a pro rata basis by each outstanding share of that class.
 
                                     TAXES
 
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
 
    No  attempt has been made to present  a detailed explanation of the federal,
state, or  local income  tax treatment  of the  Portfolio or  its  shareholders.
Accordingly,  shareholders  are urged  to consult  their tax  advisers regarding
specific questions as to federal, state and local income taxes.
 
    The Portfolio  is  treated as  a  separate  entity for  federal  income  tax
purposes  and  is not  combined  with the  Fund's  other portfolios.  It  is the
Portfolio's intent to continue to qualify for the special tax treatment afforded
regulated investment  companies under  Subchapter M  of the  Code, so  that  the
Portfolio  will  be relieved  of  federal income  tax on  that  part of  its net
investment income and net capital gain that is distributed to shareholders.
 
   
    The Portfolio intends  to distribute  substantially all of  its taxable  net
investment  income (including,  for this purpose,  the excess  of net short-term
capital gain over net  long-term capital loss)  to shareholders. Dividends  from
the  Portfolio's net investment  income are taxable  to shareholders as ordinary
income, whether received  in cash or  in additional shares.  The Portfolio  will
report annually to its shareholders the amount of dividend income qualifying for
the corporate dividend received deduction.
    
 
    Distributions  of net capital gain (the excess of net long-term capital gain
over net  short-term capital  loss)  are taxable  to shareholders  as  long-term
capital  gain, regardless of  how long shareholders have  held their shares. The
Portfolio will send reports annually to  its shareholders of the federal  income
tax status of all distributions made during the preceding year.
 
    The   Portfolio  intends   to  make   sufficient  distributions   or  deemed
distributions of its ordinary income and capital gain net income (the excess  of
short-term  and  long-term capital  gain over  short-term and  long-term capital
loss) prior to  the end of  each calendar  year to avoid  liability for  federal
excise tax.
 
                                       27
<PAGE>
    Dividends  and  other distributions  declared by  the Portfolio  in October,
November or December of any year and payable to shareholders of record on a date
in such month will be deemed to have been paid by the Portfolio and received  by
the  shareholders in that year if the distributions are paid by the Portfolio at
any time during the following January.
 
   
    The Fund may be required to withhold  and remit to the U.S. Treasury 31%  of
any  dividends, capital gains distributions and  redemption proceeds paid to any
individual or  certain other  non-corporate shareholder  (1) who  has failed  to
provide  a  correct taxpayer  identification  number (generally  an individual's
social security number  or non-individual's employer  identification number)  on
the  Application Form, (2) who is subject  to backup withholding by the Internal
Revenue Service, or (3) who has not certified to the Fund that such  shareholder
is  not  subject  to  backup  withholding. This  backup  withholding  is  not an
additional  tax,  and  any  amounts   withheld  may  be  credited  against   the
shareholder's ultimate U.S. tax liability.
    
 
    The  sale, redemption or exchange  of shares will result  in taxable gain or
loss to the selling, exchanging or redeeming shareholder, depending upon whether
the fair market value of the sale, exchange or redemption proceeds exceed or  is
less  than the shareholder's  adjusted basis in the  redeemed, exchanged or sold
shares. Any such  taxable gain or  loss generally will  be treated as  long-term
capital  gain or loss  if the shares have  been held for more  than one year and
otherwise generally  will be  treated as  short-term capital  gain or  loss.  If
capital  gain distributions have been made with  respect to shares that are sold
at a loss after  being held for six  months or less, however,  then the loss  is
treated  as  a  long-term  capital  loss  to  the  extent  of  the  capital gain
distributions.
 
    Conversion  of  shares  between  classes  are  not  taxable  events  to  the
Shareholder.
 
    Shareholders  are urged  to consult with  their tax  advisers concerning the
application of state  and local income  taxes to investments  in the  Portfolio,
which may differ from the federal income tax consequences described above.
 
    Investment  income  received by  the Portfolio  from sources  within foreign
countries may be subject to foreign income taxes withheld at the source. To  the
extent  that the Portfolio is  liable for foreign income  taxes so withheld, the
Portfolio intends to operate so as to meet the requirements of the Code to  pass
through  to the shareholders credit for  foreign income taxes paid. Although the
Portfolio intends to  meet Code  requirements to  pass through  credit for  such
taxes, there can be no assurance that the Portfolio will be able to do so.
 
    THE TAX DISCUSSION SET FORTH ABOVE IS INCLUDED FOR GENERAL INFORMATION ONLY.
PROSPECTIVE  INVESTORS SHOULD CONSULT THEIR OWN TAX ADVISERS WITH RESPECT TO THE
TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN A PORTFOLIO.
 
                             PORTFOLIO TRANSACTIONS
 
    The Adviser selects the brokers or  dealers that will execute the  purchases
and  sales  of investment  securities  for each  of  the Fund's  portfolios. The
Adviser seeks the best execution of all portfolio transactions. A portfolio  may
pay  higher commission rates than the lowest available when the Adviser believes
it is reasonable to do  so in light of the  value of the research,  statistical,
and pricing services provided by the broker effecting the transaction.
 
                                       28
<PAGE>
    It is not the Fund's practice to allocate brokerage or principal business on
the  basis of sales of shares which  may be made through intermediary brokers or
dealers. However, the Adviser may,  consistent with NASD rules, place  portfolio
orders  with qualified broker-dealers who  recommend the applicable portfolio to
their clients or who act  as agents in the purchase  of shares of the  portfolio
for their clients.
 
    Subject  to  the overriding  objective of  obtaining  the best  execution of
orders, the  Fund may  use broker-dealer  affiliates of  the Adviser,  including
Morgan  Stanley,  to effect  portfolio  brokerage transactions  under procedures
adopted by the Fund's Board of Directors. For such transactions, the  commission
rates  and other remuneration paid to Morgan Stanley or other affiliates must be
fair  and  reasonable  in  comparison  to  those  of  other  broker-dealers  for
comparable  transactions involving  similar securities  being purchased  or sold
during a comparable time period.
 
PORTFOLIO TURNOVER
 
   
    The Portfolio generally  does not  invest for  short-term trading  purposes,
however,   when  circumstances  warrant,  the   Portfolio  may  sell  investment
securities without regard  to the  length of time  they have  been held.  Market
conditions  in a given year could result in a higher or lower portfolio turnover
rate than expected and the Portfolio will not consider portfolio turnover rate a
limiting factor in  making investment decisions  consistent with its  respective
objective  and policies. For the  fiscal year ended December  31, 1996, the U.S.
Real Estate  Portfolio had  a  portfolio turnover  rate  of 171%.  As  portfolio
turnover  increases, the Portfolio  may expect to  pay correspondingly increased
brokerage and trading costs. In addition to transaction costs, higher  portfolio
turnover  may result  in the  realization of  capital gains.  As discussed under
"Taxes,"  to  the  extent  net  short-term  capital  gains  are  realized,   any
distributions  resulting  from such  gains  are considered  ordinary  income for
federal income tax purposes.
    
 
                              GENERAL INFORMATION
 
DESCRIPTION OF COMMON STOCK
 
   
    The Fund  was organized  as a  Maryland corporation  on June  16, 1988.  The
Articles  of Incorporation, as amended and restated, permit the Fund to issue up
to 35 billion shares of common stock,  with $.001 par value per share.  Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number  of shares the  Fund is authorized  to issue without  the approval of the
shareholders of the Fund. The Board of Directors has the power to designate  one
or  more classes of  shares of common  stock and to  classify and reclassify any
unissued shares with respect to such classes. The shares of common stock of each
Portfolio are currently classified into two classes, the Class A shares and  the
Class  B shares, except for the  International Small Cap Portfolio, Money Market
and Municipal Money Market Portfolios which offer only Class A shares.
    
 
    The shares of the Portfolio, when issued, will be fully paid, nonassessable,
fully transferable and redeemable at the  option of the holder. The shares  have
no  preference  as  to  conversion,  exchange,  dividends,  retirement  or other
features and  have no  pre-emptive  rights. The  shares  of the  Portfolio  have
non-cumulative  rights, which  means that  the holders of  more than  50% of the
shares voting for the election of Directors  can elect 100% of the Directors  if
they  choose  to do  so.  Persons or  organizations owning  25%  or more  of the
outstanding shares of the Portfolio may be presumed to "control" (as defined  in
the  1940 Act) the  Portfolio. Under Maryland  law, the Fund  is not required to
hold an annual meeting of  its shareholders unless required  to do so under  the
1940 Act.
 
                                       29
<PAGE>
REPORTS TO SHAREHOLDERS
 
    The  Fund will send to its  shareholders annual and semi-annual reports; the
financial statements  appearing in  annual reports  are audited  by  independent
accountants.  Monthly unaudited portfolio  data is also  available from the Fund
upon request.
 
    In addition, the Adviser, or its agent, as Transfer Agent, will send to each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
 
CUSTODIAN
 
    Chase is the Fund's custodian for domestic and certain foreign assets. Chase
is not an  affiliate of  the Adviser or  the Distributor.  Morgan Stanley  Trust
Company,  Brooklyn,  New York  ("MSTC"),  an affiliate  of  the Adviser  and the
Distributor, acts as  the Fund's custodian  for assets held  outside the  United
States  and employs subcustodians approved by the Board of Directors of the Fund
in accordance with regulations of the Securities and Exchange Commission for the
purpose of providing  custodial services  for such  assets. MSTC  may also  hold
certain  domestic assets for  the Fund. For more  information on the custodians,
see "General Information -- Custody Arrangements" in the Statement of Additional
Information.
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
    Chase  Global   Funds  Services   Company,   73  Tremont   Street,   Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
 
INDEPENDENT ACCOUNTANTS
 
   
    Price  Waterhouse LLP  serves as  independent accountants  for the  Fund and
audits the annual financial statements of each portfolio.
    
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       30
<PAGE>
   MORGAN STANLEY INSTITUTIONAL FUND, INC.
          U.S. REAL ESTATE PORTFOLIO
           P.O. BOX 2798, BOSTON, MA 02208-2798
 
                           ACCOUNT REGISTRATION FORM
 
<TABLE>
<C>   <S>                                       <C>
                                                If you need assistance in filling out this form for the
      ACCOUNT INFORMATION                       Morgan Stanley Institutional Fund, please contact your
      Fill in where applicable                  Morgan Stanley representative or call us toll free
                                                1-(800)-548-7786. Please print all items except signature,
                                                and mail to the Fund at the address above.
 
  A)  REGISTRATION
      1. INDIVIDUAL
      2. JOINT TENANTS
        (RIGHTS OF SURVIVORSHIP PRESUMED
      UNLESS
        TENANCY IN COMMON
        IS INDICATED)
</TABLE>
 
1.
                               First
Name                          Initial                               Last Name
 
2.
                               First
Name                          Initial                               Last Name
 
                               First
Name                          Initial                               Last Name
 
<TABLE>
<C>   <S>                                       <C>
      3. CORPORATIONS,
        TRUSTS AND OTHERS
        Please call the Fund for additional
      documents that may be required to set up
      account and to authorize transactions.
</TABLE>
 
3.
 
<TABLE>
<S>                   <C>               <C>                  <C>              <C>
Type of               / / INCORPORATED  / / UNINCORPORATED   / / PARTNERSHIP  / / UNIFORM GIFT/TRANSFER TO MINOR
Registration:                           ASSOCIATION                             (ONLY ONE CUSTODIAN AND MINOR PERMITTED)
</TABLE>
 
/ / TRUST ________________________  / / OTHER (Specify) ________________________
 
<TABLE>
<C>   <S>                                            <C>
  B)  MAILING ADDRESS
      Please fill in completely, including
      telephone number(s).
</TABLE>
 
/ / United States Citizen  / / Resident Alien
                   Street or P.O. Box
                   City
                   State                   Zip
Home Telephone No.                   Business Telephone No.
 
/ / Non-Resident Alien:
 
Permanent Address (Where you reside permanently for tax purposes)
                   Street Address
                   City
                   Country                   Postal Code
Home Telephone No.                    Business Telephone No.
 
Current Mailing Address (If different from Permanent Address)
                   Street Address
                   City
                   Country
Postal Code
Home Telephone No.                   Business Telephone No.
 
<TABLE>
<S>   <S>                                       <C>                                       <C>
  C)  TAXPAYER                                  Enter  your Taxpayer Identification Number. For most individual taxpayers, this is
      IDENTIFICATION                            your Social Security Number.
      NUMBER
      1. INDIVIDUAL
      2. JOINT TENANTS
        (RIGHTS OF SURVIVORSHIP PRESUMED
      UNLESS
        TENANCY IN COMMON
        IS INDICATED)
</TABLE>
<PAGE>
<TABLE>
<S>   <S>                                       <C>                                       <C>
      For Custodian account
      of a minor (Uniform
      Gifts/Transfers to Minor
      Acts), give the Social
      Security Number of
      the minor
                                                1.           TAXPAYER IDENTIFICATION      OR               SOCIAL SECURITY NUMBER
                                                NUMBER ("TIN")                            ("SSN")
                                                2. TIN                                    OR SSN
                                                TIN                                       OR SSN
                                                IMPORTANT TAX INFORMATION
                                                You (as a payee) are  required by law to provide  us (as payer) with your  correct
                                                TIN(s)  or SSN(s). Accounts that have a missing or incorrect TIN(s) or SSN(s) will
                                                be subject to  backup withholding at  a 31% rate  on dividends, distributions  and
                                                other  payments. If you have  not provided us with  your correct TIN(s) or SSN(s),
                                                you may be  subject to  a $50  penalty imposed  by the  Internal Revenue  Service.
                                                Backup  withholding is not an additional tax; the tax liability of persons subject
                                                to backup  withholding  will  be  reduced  by  the  amount  of  tax  withheld.  If
                                                withholding  results  in  an  overpayment  of taxes,  a  refund  may  be obtained.
                                                You may  be notified  that you  are subject  to backup  withholding under  Section
                                                3406(a)(1)(C) of the Internal Revenue Code because you have underreported interest
                                                or  dividends or you  were required to, but  failed to, file  a return which would
                                                have included a reportable interest or dividend payment.
</TABLE>
 
<PAGE>
 
   
<TABLE>
<C>   <S>                                       <C>                             <C>                   <C>
  D)  PORTFOLIO AND                             For Purchase of the following   / / Class A Shares $  / / Class B Shares $
      CLASS SECTION                             Portfolio:
      (Class A shares minimum $500,000 for the  U.S. Real Estate Portfolio
      Portfolio and Class B shares minimum
      $100,000 for the Portfolio). Please
      indicate class and amount.
                                                                                Total Initial Investment $
</TABLE>
    
 
<TABLE>
<C>   <S>                                       <C>
  E)  METHOD OF
      INVESTMENT
      Please indicate portfolio, manner of
      payment.
</TABLE>
 
Payment by:
 
/ / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND,
INC.--PORTFOLIO NAME)
 
<TABLE>
<S>                                                                                 <C>
/ / Exchange $ From                                                                           -- - - - - - - - - - -- - -
                                                      Name of Portfolio                               Account No.
/ / Account previously established by:  / / Phone exchange  / / Wire on                       -- - - - - - - - - - -- - -
                                                                                            Account No.               (Check
                                                                                      (Previously assigned by the Fund)     Digit)
                                                                            Date
</TABLE>
 
<TABLE>
<C>   <S>                                       <C>
  F)  DISTRIBUTION                              Income dividends and capital gains distributions (if any) to
      OPTION                                    be reinvested in additional shares unless either box below
                                                is checked.
                                                / / Income dividends to be paid in cash, capital gains
                                                distributions (if any) in shares.
                                                / / Income dividends and capital gains distributions (if
                                                any) to be paid in cash.
</TABLE>
<TABLE>
<C>   <S>                             <C>
  G)  TELEPHONE                       / / I/we hereby authorize the Fund and
      REDEMPTION                      its agents to honor any telephone
      AND EXCHANGE                    requests to wire redemption proceeds to
      OPTION                          the commercial bank indicated at right
      Please select at time of        and/or mail redemption proceeds to the
      initial application if you      name and address in which my/our fund
      wish to redeem or exchange      account is registered if such requests
      shares by telephone. A          are believed to be authentic.
      SIGNATURE GUARANTEE IS          The Fund and the Fund's Transfer Agent
      REQUIRED IF BANK ACCOUNT IS     will employ reasonable procedures to
      NOT REGISTERED IDENTICALLY TO   confirm that instructions communicated
      YOUR FUND ACCOUNT.              by telephone are genuine. These
      TELEPHONE REQUESTS FOR          procedures include requiring the
      REDEMPTIONS OR EXCHANGE WILL    investor to provide certain personal
      NOT BE HONORED UNLESS THE BOX   identification information at the time
      IS CHECKED.                     an account is opened and prior to
                                      effecting each transaction requested by
                                      telephone. In addition, all telephone
                                      transaction requests will be recorded
                                      and investors may be required to provide
                                      additional telecopied written
                                      instructions of transaction requests.
                                      Neither the Fund nor the Transfer Agent
                                      will be responsible for any loss,
                                      liability, cost or expense for following
                                      instructions received by telephone that
                                      it reasonably believes to be genuine.
 
<CAPTION>
  G)
      Name of COMMERCIAL Bank (Not Savings Bank)
      Bank Account No.
                                                   Bank ABA No.
      Name(s) in which your BANK Account is Established
      Bank's Street Address
      City                           State                           Zip
</TABLE>
 
<TABLE>
<C>   <S>                        <C>
  H)  INTERESTED PARTY
      OPTION                                                                                      Name
      In addition to the
      account statement sent to
      my/our registered                                                                          Address
      address, I/we hereby
      authorize the fund to      City         State         Zip Code
      mail duplicate statements
      to the name and address
      provided at right.
</TABLE>
 
<TABLE>
<C>   <S>                                       <C>
  I)  DEALER
      INFORMATION
                                                Representative Name                        Representative
                                                No.                            Branch
                                                No.
</TABLE>
 
<PAGE>
 
<TABLE>
<C>   <S>                                       <C>
  J)  SIGNATURE OF
      ALL HOLDERS
      AND TAXPAYER
      CERTIFICATION
      Sign Here ,
</TABLE>
 
<TABLE>
<S>                                                           <C>
The undersigned certify that I/we have full authority and legal capacity to purchase and redeem shares of the Fund and
affirm that I/we have received a current Prospectus of the Morgan Stanley Institutional Fund, Inc. and agree to be bound
by its terms.
  BY SIGNING THIS APPLICATION, I/WE HEREBY CERTIFY UNDER PENALTIES OF PERJURY THAT THE INFORMATION ON THIS APPLICATION  IS
COMPLETE AND CORRECT AND THAT AS REQUIRED BY FEDERAL LAW (PLEASE CHECK APPLICABLE BOXES BELOW):
/ / U.S. CITIZEN(S)/TAXPAYER(S):
       /  / I/WE CERTIFY THAT (1) THE NUMBER(S) SHOWN ABOVE ON  THIS FORM IS/ARE THE CORRECT SSN(S) OR TIN(S) AND (2) I/WE
           ARE NOT SUBJECT TO ANY BACKUP WITHHOLDING EITHER BECAUSE (A) I/WE ARE EXEMPT FROM BACKUP WITHHOLDING; (B)  I/WE
           HAVE NOT BEEN NOTIFIED BY THE INTERNAL REVENUE SERVICE ("IRS") THAT I/WE ARE SUBJECT TO BACKUP WITHHOLDING AS A
           RESULT  OF A FAILURE TO REPORT ALL INTEREST OR DIVIDENDS; OR (C) THE IRS HAS NOTIFIED ME/US THAT I AM/WE ARE NO
           LONGER SUBJECT TO BACKUP WITHHOLDING.
       / / IF NO TIN(S) OR SSN(S) HAS/HAVE BEEN PROVIDED ABOVE,  I/WE HAVE APPLIED, OR INTEND TO APPLY, TO THE IRS OR  THE
           SOCIAL SECURITY ADMINISTRATION FOR A TIN OR A SSN AND I/WE UNDERSTAND THAT IF I/WE DO NOT PROVIDE EITHER NUMBER
           TO CHASE GLOBAL FUNDS SERVICES COMPANY ("CGFSC") WITHIN 60 DAYS OF THE DATE OF THIS APPLICATION OR IF I/WE FAIL
           TO  FURNISH MY/OUR CORRECT SSN(S) OR TIN(S),  I/WE MAY BE SUBJECT TO A  PENALTY AND A 31% BACKUP WITHHOLDING ON
           DISTRIBUTIONS AND REDEMPTION PROCEEDS.  (PLEASE PROVIDE EITHER NUMBER  ON IRS FORM W-9).  YOU MAY REQUEST  SUCH
           FORM BY CALLING CGFSC AT 800-282-4404.
/ / NON-U.S. CITIZEN(S)/TAXPAYER(S)
  UNDER  PENALTIES OF  PERJURY, I/WE CERTIFY  THAT I/WE  ARE NOT U.S.  CITIZENS OR  RESIDENTS AND I/WE  ARE EXEMPT FOREIGN
PERSONS AS DEFINED BY THE INTERNAL REVENUE SERVICE.
 
THE INTERNAL REVENUE SERVICE DOES NOT REQUIRE YOUR CONSENT TO ANY PROVISION OF THIS DOCUMENT OTHER THAN THE CERTIFICATIONS
REQUIRED TO AVOID BACKUP WITHHOLDING.
 
(X)                                                           (X)
Signature                                                     Date Signature (if joint account, both must sign)   Date
</TABLE>
<PAGE>
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
 
  NO  DEALER, SALES  REPRESENTATIVE OR ANY  OTHER PERSON HAS  BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE  CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS  HAVING BEEN AUTHORIZED BY THE FUND  OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF  THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION  TO
ANY  PERSON TO WHOM  IT IS UNLAWFUL TO  MAKE SUCH OFFER  OR SOLICITATION IN SUCH
JURISDICTION.
 
                           --------------------------
 
                               TABLE OF CONTENTS
 
   
<TABLE>
<S>                                                 <C>
                                                    PAGE
                                                    ----
Fund Expenses.....................................    2
Financial Highlights..............................    4
Prospectus Summary................................    6
Investment Objective and Policies.................   10
Additional Investment Information.................   12
Investment Limitations............................   15
Management of the Fund............................   16
Purchase of Shares................................   18
Redemption of Shares..............................   23
Shareholder Services..............................   24
Valuation of Shares...............................   25
Performance Information...........................   26
Dividends and Capital Gains Distributions.........   26
Taxes.............................................   27
Portfolio Transactions............................   28
General Information...............................   29
Account Registration Form
</TABLE>
    
 
                           U.S. REAL ESTATE PORTFOLIO
 
                                PORTFOLIO OF THE
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
 
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
 
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
                      P.O. BOX 2798, BOSTON, MA 02208-2798
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
     ----------------------------------------------------------------------
 
                         INTERNATIONAL MAGNUM PORTFOLIO
 
                               A PORTFOLIO OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
 
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
 
                                ----------------
 
   
    Morgan  Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company, or mutual fund, which offers redeemable shares in
a   series   of   diversified   and   non-diversified   investment    portfolios
("portfolios").  The  Fund  is  designed  to  provide  clients  with  attractive
alternatives for meeting their investment needs. The Fund currently consists  of
twenty-nine  portfolios representing a  broad range of  investment choices. This
prospectus (the "Prospectus") pertains to the Class A and Class B shares of  the
International Magnum Portfolio (the "Portfolio"). The Class A and Class B shares
currently   offered  by   the  Portfolio   have  different   minimum  investment
requirements and fund  expenses. Shares of  the portfolios are  offered with  no
sales  charge, exchange  fee or redemption  fee, (except  that the International
Small Cap Portfolio may impose a transaction fee).
    
 
    The Fund is designed  to meet the investment  needs of discerning  investors
who  place a premium on quality and  personal service. With Morgan Stanley Asset
Management  Inc.  as   Adviser  and   Administrator  (the   "Adviser"  and   the
"Administrator"),  and with Morgan Stanley & Co. Incorporated ("Morgan Stanley")
as Distributor, the  Fund makes available  to institutional and  high net  worth
individual  investors a series  of portfolios which  benefit from the investment
expertise and commitment to  excellence associated with  Morgan Stanley and  its
affiliates.
 
    This Prospectus is designed to set forth concisely the information about the
Fund  that a prospective investor should know  before investing and it should be
retained for future reference. The  Fund offers additional portfolios which  are
described  in other prospectuses and under  "Prospectus Summary" below. The Fund
currently offers the following portfolios:  (i) GLOBAL AND INTERNATIONAL  EQUITY
- --  Active Country Allocation, Asian  Equity, Emerging-Markets, European Equity,
Global Equity, Gold, International  Equity, International Magnum,  International
Small  Cap, Japanese Equity  and Latin American Portfolios;  (ii) U.S. EQUITY --
Aggressive Equity,  Emerging  Growth, Equity  Growth,  Small Cap  Value  Equity,
Technology, U.S. Real Estate and Value Equity Portfolios; (iii) EQUITY AND FIXED
INCOME  -- Balanced Portfolio; (iv) FIXED INCOME -- Emerging Markets Debt, Fixed
Income, Global Fixed Income, High Yield  and Municipal Bond Portfolios; and  (v)
MONEY  MARKET -- Money Market and  Municipal Money Market Portfolios. Additional
information  about  the  Fund  is  contained  in  a  "Statement  of   Additional
Information,"  dated May 1, 1997, which is incorporated herein by reference. The
Statement of Additional Information and the prospectuses pertaining to the other
portfolios of the Fund are available upon request and without charge by  writing
or calling the Fund at the address and telephone number set forth above.
 
  THESE  SECURITIES HAVE NOT  BEEN APPROVED OR  DISAPPROVED BY THE SECURITIES
   AND EXCHANGE COMMISSION  NOR HAS THE  SECURITIES AND EXCHANGE  COMMISSION
    PASSED  UPON  THE ACCURACY  OR ADEQUACY  OF THIS  PROSPECTUS.       ANY
             REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.
 
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1997.
<PAGE>
                                 FUND EXPENSES
 
    The  following table illustrates all expenses and fees that a shareholder of
the International Magnum Portfolio will incur:
   
<TABLE>
<CAPTION>
SHAREHOLDER TRANSACTION EXPENSES
- ------------------------------------------------------------------------------------------
<S>                                                                                         <C>
Maximum Sales Load Imposed on Purchases
  Class A.................................................................................        None
  Class B.................................................................................        None
Maximum Sales Load Imposed on Reinvested Dividends
  Class A.................................................................................        None
  Class B.................................................................................        None
Deferred Sales Load
  Class A.................................................................................        None
  Class B.................................................................................        None
Redemption Fees
  Class A.................................................................................        None
  Class B.................................................................................        None
Exchange Fees
  Class A.................................................................................        None
  Class B.................................................................................        None
 
<CAPTION>
 
ANNUAL FUND OPERATING EXPENSES
- ------------------------------------------------------------------------------------------
<S>                                                                                         <C>
 (AS A PERCENTAGE OF AVERAGE NET ASSETS)
Management Fee (Net of Fee Waiver)*
  Class A.................................................................................       0.26%
  Class B.................................................................................       0.26%
12b-1 Fees
  Class A.................................................................................        None
  Class B.................................................................................       0.25%
Other Expenses
  Class A.................................................................................       0.74%
  Class B.................................................................................       0.74%
                                                                                            -----------
Total Operating Expenses (Net of Fee Waivers)*
  Class A.................................................................................       1.00%
  Class B.................................................................................       1.25%
                                                                                            -----------
                                                                                            -----------
</TABLE>
    
 
- ------------------------
   
* The Adviser has agreed  to waive its management  fees and/or to reimburse  the
  Portfolio,  if necessary, if such fees  would cause the total annual operating
  expenses of the  Portfolio to  exceed a  specified percentage  of its  average
  daily  net assets. Absent the  fee waiver, the management  fee would be 0.80%.
  Absent the  fee waiver  and/or expense  reimbursement, the  Portfolio's  total
  operating expenses would be 1.54% of the average daily net assets of the Class
  A shares and 1.69% of the average daily net assets of the Class B shares. As a
  result  of this reduction, the  Management Fee stated above  is lower than the
  contractual fee stated under  "Management of the  Fund." The Adviser  reserves
  the right to terminate any of its fee waivers and/or expense reimbursements at
  any time in its sole discretion. For further information on Fund expenses, see
  "Management of the Fund."
    
 
                                       2
<PAGE>
    The  purpose of the table  above is to assist  the investor in understanding
the various expenses  that an investor  in the Portfolio  will bear directly  or
indirectly.  Expenses and fees are  based on actual figures  for the fiscal year
ended December 31, 1996. Due to the  continuous nature of Rule 12b-1 fees,  long
term  Class  B shareholders  may pay  more  than the  equivalent of  the maximum
front-end sales  charges  otherwise permitted  by  the National  Association  of
Securities Dealers, Inc. ("NASD") Conduct Rules.
 
    The  following  example illustrates  the expenses  that you  would pay  on a
$1,000 investment assuming (1) a 5% annual rate of return and (2) redemption  at
the  end of each time period. As noted in the table above, the Portfolio charges
no redemption fees  of any kind.  The following  example is based  on the  total
operating expenses of the Portfolio after fee waivers.
 
   
<TABLE>
<CAPTION>
                                                                       1 YEAR       3 YEARS     5 YEARS    10 YEARS
                                                                     -----------  -----------  ---------  -----------
<S>                                                                  <C>          <C>          <C>        <C>
International Magnum Portfolio
  Class A..........................................................   $      10    $      32   $   *       $   *
  Class B..........................................................          13           40       *           *
</TABLE>
    
 
- ------------------------
* Because  the Portfolio  has recently  commenced operations,  the Fund  has not
  projected expenses for the Portfolio beyond the 3-year period shown.
 
    THIS EXAMPLE SHOULD  NOT BE CONSIDERED  A REPRESENTATION OF  PAST OR  FUTURE
EXPENSES  OR  PERFORMANCE. ACTUAL  EXPENSES MAY  BE GREATER  OR LESS  THAN THOSE
SHOWN.
 
                                       3
<PAGE>
                              FINANCIAL HIGHLIGHTS
 
   
    The following table provides financial highlights for the Class A and  Class
B  shares  of the  Portfolio  for each  of  the periods  presented.  The audited
financial highlights  for the  Portfolio's shares  for the  fiscal period  ended
December  31, 1996 are part  of the Fund's financial  statements which appear in
the Fund's  December  31, 1996  Annual  Report  to Shareholders  and  which  are
incorporated by reference in the Fund's Statement of Additional Information. The
Portfolio's  financial highlights  for each of  the periods  presented have been
audited by  Price  Waterhouse LLP,  whose  unqualified report  thereon  is  also
incorporated by reference in the Statement of Additional Information. Additional
performance  information is included in the Annual Report. The Annual Report and
the financial  statements  therein,  along  with  the  Statement  of  Additional
Information, are available at no cost from the Fund at the address and telephone
number  noted on  the cover page  of this Prospectus.  The following information
should be read in conjunction with the financial statements and notes thereto.
    
 
                                       4
<PAGE>
                         INTERNATIONAL MAGNUM PORTFOLIO
 
   
<TABLE>
<CAPTION>
                                                                                            CLASS A
                                                                                           ---------   CLASS B
                                                                                                      ---------
                                                                                               PERIOD FROM
                                                                                            MARCH 15, 1996* TO
                                                                                            DECEMBER 31, 1996
                                                                                           --------------------
<S>                                                                                        <C>        <C>
NET ASSET VALUE, BEGINNING OF PERIOD.....................................................  $   10.00  $   10.00
                                                                                           ---------  ---------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1)..............................................................       0.06       0.01
  Net Realized and Unrealized Gain on Investments........................................       0.76       0.78
                                                                                           ---------  ---------
    Total from Investment Operations.....................................................       0.82       0.79
                                                                                           ---------  ---------
DISTRIBUTIONS
  Net Investment Income..................................................................      (0.13)     (0.13)
  In Excess of Net Investment Income.....................................................      (0.02)     (0.02)
  Net Realized Gain......................................................................      (0.01)     (0.01)
                                                                                           ---------  ---------
    Total Distributions..................................................................      (0.16)     (0.16)
                                                                                           ---------  ---------
NET ASSET VALUE, END OF PERIOD...........................................................  $   10.66  $   10.63
                                                                                           ---------  ---------
                                                                                           ---------  ---------
TOTAL RETURN.............................................................................       8.25%      7.90%
                                                                                           ---------  ---------
                                                                                           ---------  ---------
RATIOS AND SUPPLEMENTAL DATA:............................................................
  Net Assets, End of Period (Thousands)..................................................  $  85,316  $  23,173
  Ratio of Expenses to Average Net Assets (1)............................................       1.00%**      1.25%**
  Ratio of Net Investment Income to Average Net Assets (1)...............................       0.99%**      0.60%**
  Portfolio Turnover Rate................................................................         18%        18%
  Average Commission Rate#...............................................................    $0.0211    $0.0211
</TABLE>
    
 
- ------------------------
 
   
<TABLE>
<C>  <S>                                                                                     <C>        <C>
(1)  Effect of voluntary expense limitation during the period:
       Per share benefit to net investment income..........................................      $0.03      $0.01
     Ratios before expense limitation:
       Expenses to Average Net Assets......................................................       1.54%**      1.69%**
       Net Investment Income to Average Net Assets.........................................       0.44%**      0.15%**
</TABLE>
    
 
   
 * Commencement of operations.
    
   
 ** Annualized
    
   
 # For the period ended December 31,  1996, the average commission rate paid  in
   trades on which commissions were charged was 0.25% of the trade amount.
    
 
                                       5
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
 
    The   Fund  consists  of   twenty-nine  portfolios,  offering  institutional
investors and high net  worth individual investors a  broad range of  investment
choices coupled with the advantages of a no-load mutual fund with Morgan Stanley
and  its affiliates providing customized  services as Adviser, Administrator and
Distributor. Each portfolio offers Class A shares and, except the  International
Small Cap, Money Market and Municipal Money Market Portfolios, also offers Class
B  shares. Each portfolio has its own investment objective and policies designed
to meet its specific goals. The investment objective of the Portfolio  described
in this Prospectus is as follows:
 
    -The  INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation by
     investing primarily in equity securities  of non-U.S. issuers domiciled  in
     EAFE countries.
 
    The  other portfolios of the Fund  are described in other prospectuses which
may be obtained from the Fund at the address and phone number noted on the cover
of this  Prospectus. The  investment objectives  of these  other portfolios  are
listed below.
 
    GLOBAL AND INTERNATIONAL EQUITY:
 
    -The   ACTIVE   COUNTRY   ALLOCATION  PORTFOLIO   seeks   long-term  capital
     appreciation by investing in accordance with country weightings  determined
     by  the  Adviser in  equity securities  of non-U.S.  issuers which,  in the
     aggregate, replicate broad country indices.
 
    -The  ASIAN  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation   by
     investing primarily in equity securities of Asian issuers.
 
    -The  CHINA GROWTH PORTFOLIO seeks to provide long-term capital appreciation
     by investing  primarily in  equity securities  of issuers  in The  People's
     Republic of China, Hong Kong and Taiwan.
 
    -The  EMERGING  MARKETS PORTFOLIO  seeks  long-term capital  appreciation by
     investing primarily in equity securities of emerging country issuers.
 
    -The EUROPEAN  EQUITY  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing primarily in equity securities of European issuers.
 
    -The  GLOBAL  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing primarily in equity securities  of issuers throughout the  world,
     including U.S. issuers.
 
    -The  GOLD  PORTFOLIO  seeks  long-term  capital  appreciation  by investing
     primarily in equity securities of  foreign and domestic issuers engaged  in
     gold-related activities.
 
    -The  INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation by
     investing primarily in equity securities of non-U.S. issuers.
 
    -The INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital  appreciation
     by investing primarily in equity securities of non-U.S. issuers with equity
     market capitalizations of less than $1 billion.
 
    -The  JAPANESE  EQUITY  PORTFOLIO seeks  long-term  capital  appreciation by
     investing primarily in equity securities of Japanese issuers.
 
                                       6
<PAGE>
   
    -The LATIN  AMERICAN  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing  primarily in  equity securities  of Latin  American issuers and,
     from time to time, debt securities  issued or guaranteed by Latin  American
     governments or governmental entities.
    
 
    U.S. EQUITY:
 
    -The  AGGRESSIVE EQUITY  PORTFOLIO seeks  capital appreciation  by investing
     primarily in corporate equity and equity-linked securities.
 
    -The EMERGING  GROWTH  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing  primarily  in  growth-oriented equity  securities  of  small- to
     medium-sized corporations.
 
    -The  EQUITY  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing   in  growth-oriented  equity  securities  of  medium  and  large
     capitalization companies.
 
    -The MICROCAP PORTFOLIO  seeks long-term capital  appreciation by  investing
     primarily in growth-oriented equity securities of small corporations.
 
    -The  SMALL CAP VALUE EQUITY PORTFOLIO  seeks high long-term total return by
     investing in  undervalued  equity  securities  of  small-  to  medium-sized
     companies.
 
    -The  TECHNOLOGY PORTFOLIO seeks long-term capital appreciation by investing
     primarily in equity  securities of companies  that, in the  opinion of  the
     Portfolio's   investment  adviser,  are  expected  to  benefit  from  their
     involvement in technology and technology-related industries.
 
    -The U.S.  REAL ESTATE  PORTFOLIO  seeks to  provide above  average  current
     income  and long-term capital appreciation by investing primarily in equity
     securities of companies in  the U.S. real  estate industry, including  real
     estate investment trusts.
 
    -The  VALUE EQUITY PORTFOLIO seeks high  total return by investing in equity
     securities which the  Adviser believes  to be undervalued  relative to  the
     stock market in general at the time of purchase.
 
    EQUITY AND FIXED INCOME:
 
    -The  BALANCED PORTFOLIO seeks high total return while preserving capital by
     investing in  a  combination of  undervalued  equity securities  and  fixed
     income securities.
 
    FIXED INCOME:
 
    -The  EMERGING MARKETS DEBT  PORTFOLIO seeks high  total return by investing
     primarily  in  debt  securities   of  government,  government-related   and
     corporate issuers located in emerging countries.
 
    -The  FIXED INCOME PORTFOLIO seeks to produce a high total return consistent
     with the preservation of capital by investing in a diversified portfolio of
     fixed income securities.
 
    -The GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real  rate
     of  return while preserving capital by investing in fixed income securities
     of issuers throughout the world, including U.S. issuers.
 
    -The HIGH YIELD PORTFOLIO seeks to  maximize total return by investing in  a
     diversified  portfolio of high  yield fixed income  securities that offer a
     yield above  that  generally available  on  debt securities  in  the  three
     highest rating categories of the recognized rating services.
 
    -The  MORTGAGE-BACKED SECURITIES PORTFOLIO seeks to  produce as high a level
     of current  income  as  is  consistent  with  preservation  of  capital  by
     investing  primarily  in  a  variety  of  investment-grade  mortgage-backed
     securities.
 
                                       7
<PAGE>
    -The MUNICIPAL  BOND PORTFOLIO  seeks to  produce a  high level  of  current
     income  consistent with preservation of principal by investing primarily in
     municipal obligations, the interest on which is exempt from federal  income
     tax.
 
    MONEY MARKET:
 
    -The  MONEY MARKET PORTFOLIO  seeks to maximize  current income and preserve
     capital while maintaining  high levels  of liquidity  through investing  in
     high quality money market instruments with remaining maturities of one year
     or less.
 
    -The  MUNICIPAL MONEY MARKET PORTFOLIO  seeks to maximize current tax-exempt
     income and  preserve capital  while maintaining  high levels  of  liquidity
     through  investing in high-quality money  market instruments with remaining
     maturities of one year or less which are exempt from federal income tax.
 
   THE CHINA  GROWTH, MICROCAP  AND  MORTGAGE-BACKED SECURITIES  PORTFOLIOS  ARE
   CURRENTLY NOT BEING OFFERED.
 
INVESTMENT MANAGEMENT
 
   
    Morgan  Stanley Asset Management  Inc., a wholly-owned  subsidiary of Morgan
Stanley Group  Inc.,  which,  together  with  its  affiliated  asset  management
companies,  at March  31, 1997  had in  excess of  $118 billion  in assets under
management as  an  investment  manager  or  as  a  fiduciary  adviser,  acts  as
investment  adviser to the Fund  and each of its  portfolios. See "Management of
the Fund -- Investment Adviser" and "Management of the Fund -- Administrator."
    
 
HOW TO INVEST
 
    Class A shares  of the Portfolio  are offered directly  to investors at  net
asset  value with no  sales commission or  12b-1 charges. Class  B shares of the
Portfolio are offered at net  asset value with no  sales commission, but with  a
12b-1  fee, which  is accrued daily  and paid  quarterly, equal to  0.25%, on an
annualized basis,  of  the Class  B  shares'  average daily  net  assets.  Share
purchases may be made by sending investments directly to the Fund or through the
Distributor.  The minimum initial investment, generally, is $500,000 for Class A
shares and $100,000  for Class B  shares of the  Portfolio. The minimum  initial
investment amount is reduced for certain categories of investors. For additional
information  on  how to  purchase shares  and  minimum initial  investments, see
"Purchase of Shares."
 
HOW TO REDEEM
 
    Shares of the Portfolio may  be redeemed at any  time, without cost, at  the
net  asset value  per share  of shares of  the applicable  class next determined
after receipt of  the redemption request.  The redemption price  may be more  or
less  than the purchase  price. Certain redemptions  that cause the  value of an
account to remain for  a continuous 60-day period  below the minimum  investment
amount for Class A or for Class B shares may result in involuntary redemption or
automatic  conversion. For  additional information on  how to  redeem shares and
involuntary redemption or conversion, see "Purchase of Shares -- Minimum Account
Sizes and Involuntary Redemption of Shares" and "Redemption of Shares."
 
                                       8
<PAGE>
RISK FACTORS
 
   
    The  investment  policies  of  the   Portfolio  entail  certain  risks   and
considerations  of which an investor should  be aware. The Portfolio will invest
in securities of foreign issuers, including issuers in emerging countries, which
are subject to certain risks not typically associated with domestic  securities,
including  (1) restrictions on foreign investment and on repatriation of capital
invested in  foreign  countries, (2)  currency  fluctuations, (3)  the  cost  of
converting  foreign currency into  U.S. dollars, (4)  potential price volatility
and lesser liquidity of shares traded  on foreign country securities markets  or
lack  of a secondary  trading market for  such securities and  (5) political and
economic risks, including the risk of nationalization or expropriation of assets
and the risk  of war.  In addition,  accounting, auditing,  financial and  other
reporting  standards in foreign  countries are not  equivalent to U.S. standards
and therefore, disclosure of  certain material information may  not be made  and
less  information may be  available to investors  investing in foreign countries
than in the United States. There is also generally less governmental  regulation
of  the  securities industry  in foreign  countries than  in the  United States.
Moreover, it may be more difficult to  obtain a judgment in a court outside  the
United  States.  The  Portfolio  may invest  in  certain  derivatives, including
options, futures and options on futures. These investments entail certain  costs
and  risks, including imperfect correlation between the value of securities held
by the Portfolio and the value of the particular derivative instrument, and  the
risk that the Portfolio could not close out a derivatives position when it would
be most advantageous to do so. In addition, the Portfolio may invest illiquid or
restricted  securities, investment companies and repurchase agreements, lend its
portfolio securities, purchase securities on  a when-issued or delayed  delivery
basis  and invest in  foreign currency forward contracts  to hedge currency risk
associated with investment  in non-U.S. dollar  denominated securities. Each  of
these  investment strategies involves  specific risks which  are described under
"Investment Objective and Policies" and "Additional Investment Information."
    
 
                                       9
<PAGE>
                       INVESTMENT OBJECTIVE AND POLICIES
 
    The investment objective of  the Portfolio is  to provide long-term  capital
appreciation.  The  production  of  any current  income  is  incidental  to this
objective. The Portfolio seeks to  achieve its objective by investing  primarily
in  equity  securities  of  non-U.S. issuers  domiciled  in  the  EAFE countries
(defined below). The  countries in  which the  Portfolio will  invest are  those
comprising  the Morgan Stanley  Capital International EAFE  Index (the "Index"),
which includes Australia, Japan,  New Zealand, most  nations located in  Western
Europe  and certain developed countries in Asia, such as Hong Kong and Singapore
(each an "EAFE country," and collectively the "EAFE countries"). At least 65% of
the total  assets of  the Portfolio  will be  invested in  equity securities  of
issuers  in at least three different  EAFE countries under normal circumstances.
The Portfolio's investment objective  is a fundamental policy  which may not  be
changed without the approval of a majority of the Portfolio's outstanding voting
securities. There is no assurance that the Portfolio will attain its objective.
 
    The  Portfolio invests primarily in  equity securities, which include common
and preferred stocks, convertible securities and rights and warrants to purchase
common stocks  and  may be  denominated  in any  currency.  In addition  to  the
investments  and strategies described below, the Portfolio may invest in certain
securities and obligations as set  forth in "Additional Investment  Information"
below  and  as  described  under "Investment  Objectives  and  Policies"  in the
Statement of Additional Information. The investment policies described below are
not fundamental policies and may be changed without shareholder approval.
 
   
    By analyzing a variety of  macroeconomic and political factors, the  Adviser
develops  fundamental  projections  on comparative  interest  rates, currencies,
corporate profits and economic growth  among the various regions represented  in
the   Index.  These  projections  are  used  to  establish  regional  allocation
strategies. Within these regional allocations,  the Adviser then selects  equity
securities among issuers of a region.
    
 
   
    The  Adviser's  approach in  selecting among  equity securities  within EAFE
countries is oriented  to individual stock  selection and is  value driven.  The
Adviser  identifies those equity securities which  it believes to be undervalued
in relation  to  the issuer's  assets,  cash  flow, earnings  and  revenues.  In
selecting investments, the Adviser utilizes the research of a number of sources,
including  Morgan  Stanley Capital  International, an  affiliate of  the Adviser
located in Geneva,  Switzerland. Portfolio holdings  are regularly reviewed  and
subjected  to fundamental analysis to determine whether they continue to conform
to the Adviser's investment criteria. Equity securities which no longer  conform
to such investment criteria are sold.
    
 
   
    Although  the  Portfolio intends  to invest  primarily in  equity securities
listed on stock exchanges in EAFE countries, the Portfolio may invest in  equity
securities  that are traded over the counter or that are not admitted to listing
on a stock exchange or dealt in a  regulated market. As a result of the  absence
of  a  public trading  market,  such securities  may  pose liquidity  risks. The
Portfolio may also  invest in  private placements or  initial public  offerings.
Such  investments generally  entail short-term liquidity  risks. See "Additional
Investment Information -- Non-Publicly Traded Securities, Private Placements and
Restricted Securities."
    
 
   
    The Portfolio may invest  up to 10%  of its total  assets in (i)  investment
funds  with investment objectives similar to that  of the Portfolio and (ii) for
temporary purposes, money market  funds and pooled  investment vehicles. If  the
Portfolio  invests in  other investment funds,  stockholders will  bear not only
their proportionate share of the expenses of the Portfolio (including  operating
expenses  and  fees  of the  Adviser),  but  also will  indirectly  bear similar
expenses of the underlying investment fund.
    
 
                                       10
<PAGE>
    Although the Portfolio anticipates being fully invested in equity securities
of EAFE countries, the Portfolio may invest, under normal circumstances for cash
management purposes, up to 35% of  its total assets in certain short-term  (less
than  twelve months to maturity) and medium-term (not greater than five years to
maturity) debt securities  or hold  cash. In addition,  for temporary  defensive
purposes  during  periods in  which the  Adviser  believes changes  in economic,
financial or political conditions make it advisable, the Portfolio may invest up
to 100% of its total assets  in such short-term and medium-term debt  securities
or  hold  cash  as  described  in  "Additional  Investment  Information  -- Debt
Securities and Temporary Investments."
 
                       ADDITIONAL INVESTMENT INFORMATION
 
    DEBT SECURITIES AND TEMPORARY INVESTMENTS.   The short-term and  medium-term
debt  securities in which the Portfolio may invest consist of (a) obligations of
governments,  agencies  or  instrumentalities  of   any  member  state  of   the
Organization  for Economic  Cooperation and Development  ("OECD"), including the
United States; (b) bank deposits and bank obligations (including certificates of
deposit, time deposits and  bankers' acceptances) of  banks organized under  the
laws  of any member state of the  OECD, including the United States, denominated
in any currency; (c)  finance company and corporate  commercial paper and  other
short-term  corporate debt obligations of  corporations organized under the laws
of any  member state  of the  OECD,  including the  United States,  meeting  the
Portfolio's  credit quality  standards, provided  that no  more than  20% of the
Portfolio's assets is invested  in any one of  such issuers. The short-term  and
medium-term  debt securities  in which  the Portfolio  may invest  will be rated
investment grade  by  recognized  rating  services  such  as  Moody's  Investors
Service,  Inc. ("Moody's")  or Standard &  Poor's Ratings Group  ("S&P") (in the
case of Moody's and S&P,  meaning rated A or higher  by either), or if  unrated,
will be determined to be of comparable quality by the Adviser. During periods in
which   the  Adviser  believes  changes  in  economic,  financial  or  political
conditions make it advisable, for temporary defensive purposes the Portfolio may
reduce its holdings  in equity and  other securities and  may invest in  certain
short-term  (less than twelve  months to maturity)  and medium-term (not greater
than five years to maturity) debt securities or may hold cash.
 
   
    FOREIGN CURRENCY FORWARD CONTRACTS.   The Portfolio  may enter into  foreign
currency  forward contracts ("forward contracts")  that provide for the purchase
or sale of an amount of a specified currency at a future date. The Portfolio may
use such contracts to  protect against a decline  in a foreign currency  against
the  U.S. dollar between the  trade date and settlement  date when the Portfolio
purchases or sells securities,  lock in the U.S.  dollar value of dividends  and
interest  on securities held by the Portfolio, and generally to protect the U.S.
dollar  value  of  securities  held  by  the  Portfolio  against  exchange  rate
fluctuation.  While forward contracts  may limit losses as  a result of exchange
rate fluctuations, they will also limit any gains that might otherwise have been
realized. The Portfolio's  Custodian may  be required  to place  cash or  liquid
securities  in  a segregated  account in  an amount  equal to  the value  of the
Portfolio's total assets committed to the consummation of forward contracts.  If
the  value  of  the  securities  placed  in  the  segregated  account  declines,
additional cash or securities will be placed in the account on a daily basis  so
that  the value  of the  account will  be at  least equal  to the  amount of the
Portfolio's commitments with respect to such contracts.
    
 
   
    FUTURES CONTRACTS  AND OPTIONS  ON  FUTURES CONTRACTS.   The  Portfolio  may
purchase  and sell futures contracts and options on futures contracts, including
but not limited to financial futures, securities index futures, foreign currency
exchange futures, and interest rate futures contracts. Futures contracts provide
for the sale by one party and purchase by another party of a specified amount of
a specific security, instrument or basket
    
 
                                       11
<PAGE>
   
thereof, at a  specific future date  and at a  specified price. An  option on  a
futures  contract is a legal contract that gives  the holder the right to buy or
sell a specified amount  of futures contracts at  a fixed or determinable  price
upon the exercise of the option.
    
 
   
    The  Portfolio may  sell securities  index futures  contracts and/or options
thereon in anticipation of or during a  market decline to attempt to offset  the
decrease in market value of investments in its portfolio, or purchase securities
index  futures in order to gain market exposure. Subject to applicable laws, the
Portfolio may engage in transactions in securities index futures contracts  (and
options  thereon)  which  are  traded  on  a  recognized  securities  or futures
exchange, or  may purchase  or  sell such  instruments in  the  over-the-counter
market. There currently are limited securities index futures and options on such
futures  in many countries,  particularly emerging countries.  The nature of the
strategies adopted by the Adviser, and the extent to which those strategies  are
used, may depend on the development of such markets.
    
 
   
    The Portfolio may engage in transactions involving foreign currency exchange
futures  contracts. Such contracts  involve an obligation to  purchase or sell a
specific currency  at a  specified future  date and  at a  specified price.  The
Portfolio may engage in such transactions to hedge their respective holdings and
commitments  against changes in  the level of  future currency rates  or to gain
exposure to a particular currency.
    
 
   
    The  Portfolio  may  engage  in   transactions  in  interest  rate   futures
transactions.  Interest rate futures contracts involve an obligation to purchase
or sell a specific  debt security, instrument or  basket thereof at a  specified
future  date at  a specified price.  The value  of the contract  rises and falls
inversely with  changes in  interest rates.  The Portfolio  may engage  in  such
transactions  to hedge their holdings of debt instruments against future changes
in interest rates.
    
 
   
    Financial futures are futures  contracts relating to financial  instruments,
such  as  U.S. Government  securities, foreign  currencies, and  certificates of
deposit. Such contracts  involve an obligation  to purchase or  sell a  specific
security, instrument or basket thereof at a specified future date at a specified
price.  Like interest  rate futures  contracts, the  value of  financial futures
contracts rises  and  falls  inversely  with  changes  in  interest  rates.  The
Portfolio  may engage in financial futures contracts for hedging and non-hedging
purposes.
    
 
   
    Under rules  adopted  by  the  Commodity  Futures  Trading  Commission,  the
Portfolio  may enter into futures contracts and options thereon for both hedging
and non-hedging purposes,  provided that  not more  than 5%  of the  Portfolio's
total  assets at the time of entering the transaction are required as margin and
option  premiums  to  secure  obligations  under  such  contracts  relating   to
activities  that do not  constitute "bona fide" hedging.  The Portfolio will not
enter into futures contracts to the  extent that its outstanding obligations  to
purchase  securities under such  contracts, in combination  with its outstanding
obligations with respect to options transactions (including options to  purchase
securities or instruments) would exceed 20% of its total assets.
    
 
   
    Gains  and losses  on futures  contracts and  options thereon  depend on the
Adviser's ability  to  predict correctly  the  direction of  securities  prices,
interest  rates and other economic factors.  Other risks associated with the use
of futures  and options  are (i)  imperfect correlation  between the  change  in
market  value of investments held by the Portfolio and the prices of futures and
options relating to  investments purchased or  sold by the  Portfolio, and  (ii)
possible  lack  of a  liquid secondary  market  for a  futures contract  and the
resulting inability to  close a futures  position. The risk  that the  Portfolio
will  be unable  to close  out a  futures position  or options  contract will be
minimized by only entering  into futures contracts  or options transactions  for
which there
    
 
                                       12
<PAGE>
   
appears to be a liquid exchange or secondary market. The risk of loss in trading
on  futures contracts in some strategies can be substantial, due both to the low
margin deposits required and the extremely  high degree of leverage involved  in
futures pricing.
    
 
    FOREIGN  INVESTMENT.   The Portfolio  may invest  in U.S. dollar-denominated
securities  of  foreign  issuers  trading  in  U.S.  markets  and  in   non-U.S.
dollar-denominated  securities of  foreign issuers. Investment  in securities of
foreign  issuers  involves  somewhat  different  investment  risks  than   those
affecting  securities of  U.S. domestic issuers.  There may  be limited publicly
available information with respect to  foreign issuers, and foreign issuers  are
not  generally subject to  uniform accounting, auditing  and financial and other
reporting standards  and requirements  comparable to  those applicable  to  U.S.
companies.  There  may also  be less  government  supervision and  regulation of
foreign securities exchanges, brokers  and listed companies  than in the  United
States. Many foreign securities markets have substantially less volume than U.S.
national  securities exchanges, and securities of  some foreign issuers are less
liquid and  more  volatile  than  securities  of  comparable  domestic  issuers.
Brokerage   commissions  and  other  transaction  costs  on  foreign  securities
exchanges are generally higher than in the United States. Dividends and interest
paid by foreign issuers may be  subject to withholding and other foreign  taxes,
which  may  decrease  the  net  return on  foreign  investments  as  compared to
dividends and interest paid  to the Portfolio by  domestic companies. It is  not
expected  that the Portfolio or its shareholders would be able to claim a credit
for U.S. tax purposes with respect  to any such foreign taxes. Additional  risks
include  future  political and  economic  developments, the  possibility  that a
foreign jurisdiction might impose or change withholding taxes on income  payable
with  respect  to  foreign  securities,  possible  seizure,  nationalization  or
expropriation of  the  foreign  issuer  or foreign  deposits  and  the  possible
adoption  of foreign governmental  restrictions such as  exchange controls. Many
emerging countries  may  have  less  stable  political  environments  than  more
developed  countries. Also, it may  be more difficult to  obtain a judgment in a
court outside the United  States. Investments in  securities of foreign  issuers
are  frequently  denominated  in  foreign  currencies,  and  the  Portfolio  may
temporarily hold uninvested  reserves in  bank deposits  in foreign  currencies.
Therefore,  the value of the Portfolio's assets  as measured in U.S. dollars may
be affected  favorably  or unfavorably  by  changes  in currency  rates  and  in
exchange  control regulations, and  the Portfolio may  incur costs in connection
with conversions between various currencies.
 
    INVESTMENT COMPANIES.  Some foreign countries have laws and regulations that
currently  preclude  direct  foreign  investment  in  the  securities  of  their
companies.  However, indirect foreign investment  in the securities of companies
listed and  traded  on the  stock  exchanges  in these  countries  is  sometimes
permitted  through investment companies which have been specifically authorized.
The Portfolio may invest in these investment companies subject to the provisions
of the Investment Company Act  of 1940, as amended  (the "1940 Act"), and  other
applicable  laws. If  the Portfolio  invests in  such investment  companies, the
Portfolio's shareholders will  bear not  only their proportionate  share of  the
expenses  of the  Portfolio (including  operating expenses  and the  fees of the
Adviser), but  also will  indirectly  bear similar  expenses of  the  underlying
investment  companies. Certain of these investment  companies referred to in the
preceding paragraph are advised by the Adviser. The Portfolio may, to the extent
permitted under  the  1940  Act  and  other  applicable  law,  invest  in  these
investment companies.
 
    LOANS  OF PORTFOLIO  SECURITIES.  The  Portfolio may lend  its securities to
brokers, dealers, domestic and foreign banks or other financial institutions for
the purpose of increasing its net investment income. These loans must be secured
continuously by cash or equivalent collateral or by a letter of credit at  least
equal to the market
 
                                       13
<PAGE>
value  of the securities  loaned plus accrued  interest or income.  There may be
risks of delay  in recovery  of the  securities or even  loss of  rights in  the
collateral should the borrower of the securities fail financially. The Portfolio
will  not enter  into securities  loan transactions  exceeding in  the aggregate
33 1/3% of the market value of the Portfolio's total assets.
 
   
    MONEY MARKET INSTRUMENTS.   The Portfolio  is permitted to  invest in  money
market   instruments,  although  the  Portfolio  intends  to  stay  invested  in
securities satisfying its primary investment objective to the extent  practical.
The  Portfolio may  make money  market investments  pending other  investment or
settlement for liquidity, or in adverse market conditions. See "Debt  Securities
and  Temporary  Investments." The  money  market investments  permitted  for the
Portfolio include  obligations  of the  U.S.  Government and  its  agencies  and
instrumentalities;  obligations of foreign sovereignties; other debt securities;
commercial  paper;  bank   obligations;  certificates   of  deposit   (including
Eurodollar certificates of deposit); and repurchase agreements.
    
 
    NON-PUBLICLY   TRADED   SECURITIES,   PRIVATE   PLACEMENTS   AND  RESTRICTED
SECURITIES.  The Portfolio may invest in securities that are neither listed on a
stock  exchange  nor   traded  over-the-counter,   including  privately   placed
securities.  Such  unlisted equity  securities may  involve  a higher  degree of
business and financial risk that can  result in substantial losses. As a  result
of the absence of a public trading market for these securities, they may be less
liquid  than publicly traded securities. Although these securities may be resold
in privately negotiated transactions, the prices realized from these sales could
be less than those  originally paid by  the Portfolio or less  than what may  be
considered   the  fair  value  of  such  securities.  Further,  companies  whose
securities are not  publicly traded  may not be  subject to  the disclosure  and
other  investor  protection  requirements  which might  be  applicable  if their
securities  were  publicly  traded.  If  such  securities  are  required  to  be
registered  under the securities laws of  one or more jurisdictions before being
resold, the Portfolio may be required to bear the expenses of registration.
 
    As a general matter, the Portfolio may  not invest more than 15% of its  net
assets  in  illiquid  securities, including  securities  for which  there  is no
readily available secondary market. Nor as  a general matter, may the  Portfolio
invest  more than 10% of its total assets in securities that are restricted from
sale to  the public  without registration  ("Restricted Securities")  under  the
Securities  Act of 1933, as amended (the "1933 Act"). However, the Portfolio may
invest up to 25% of its total assets in liquid Restricted Securities that can be
offered and sold to  qualified institutional buyers under  Rule 144A under  that
Act  ("Rule 144A Securities"). The Board of Directors has adopted guidelines and
delegated to the Adviser, subject to the supervision of the Board of  Directors,
the  daily function  of determining  and monitoring  the liquidity  of Rule 144A
securities. Rule 144A securities may become illiquid if qualified  institutional
buyers are not interested in acquiring the securities.
 
   
    OPTIONS  TRANSACTIONS.  The Portfolio may seek to increase its return or may
hedge its portfolio  investments through  options transactions  with respect  to
securities,  instruments, indices or baskets thereof  in which the Portfolio may
invest, as well  as with respect  to foreign currency.  Purchasing a put  option
gives  the Portfolio the right to sell  a specified security, currency or basket
of securities or currencies  at the exercise price  until the expiration of  the
option.  Purchasing a call  option gives the  Portfolio the right  to purchase a
specified security,  currency  or basket  of  securities or  currencies  at  the
exercise  price  until  the expiration  of  the  option. The  Portfolio  may not
purchase call and  put options to  the extent  that the value  of its  aggregate
investment in options exceeds 5% of its total assets.
    
 
                                       14
<PAGE>
   
    The  Portfolio  also  may  write  (i.e.,  sell)  put  and  call  options  on
investments held in its portfolio, as well as with respect to foreign  currency.
A  Portfolio that has written an option  receives a premium, which increases the
Portfolio's return on  the underlying security  or instrument in  the event  the
option  expires unexercised or is closed out  at a profit. However, by writing a
call option, the Portfolio will limit its opportunity to profit from an increase
in the market value of the underlying security or instrument above the  exercise
price  of the option for as long as  the Portfolio's obligation as writer of the
option continues. The  Portfolio may only  write options that  are "covered."  A
covered  call option  means that so  long as  the Portfolio is  obligated as the
writer of the  option, it  will own (i)  the underlying  security or  instrument
subject  to  the  option  or  (ii)  securities  or  instruments  convertible  or
exchangeable without  the payment  of  any consideration  into the  security  or
instrument subject to the option.
    
 
   
    By  writing (or selling) a put option, the Portfolio incurs an obligation to
buy the security or instrument underlying  the option from the purchaser of  the
put  at the option's exercise price at any time during the option period, at the
purchaser's election. Options written by the Portfolio may be exercisable by the
purchaser only on a  specific date. A  Portfolio that has  written a put  option
will  earmark or  segregate sufficient  liquid assets  to cover  its obligations
under the option.
    
 
   
    The Portfolio may  engage in  transactions in  options which  are traded  on
recognized  exchanges or  over-the-counter. There currently  are limited options
markets in  many  countries,  particularly  emerging  countries  such  as  Latin
American  countries, and the nature of the strategies adopted by the Adviser and
the extent to which those strategies are used will depend on the development  of
such  option markets. The primary  risks associated with the  use of options are
(i) imperfect  correlation between  the change  in market  value of  investments
held,  purchased or sold by the Portfolio  and the prices of options relating to
such investments; and  (ii) possible lack  of a liquid  secondary market for  an
option.
    
 
    REPURCHASE  AGREEMENTS.  The Portfolio  may enter into repurchase agreements
with brokers, dealers or  banks that meet the  credit guidelines established  by
the  Fund's Board of Directors. In a  repurchase agreement, the Portfolio buys a
security from a seller  that has agreed  to repurchase it  at a mutually  agreed
upon  date and price, reflecting the interest rate effective for the term of the
agreement. The term of  these agreements is usually  from overnight to one  week
and  never exceeds  one year.  Repurchase agreements  may be  viewed as  a fully
collateralized loan  of money  by the  Portfolio to  the seller.  The  Portfolio
always  receives securities with a  market value at least  equal to the purchase
price (including accrued interest) as  collateral, and this value is  maintained
during  the term  of the  agreement. If the  seller defaults  and the collateral
value declines, the Portfolio might incur a loss. If bankruptcy proceedings  are
commenced  with  respect to  the seller,  the  Portfolio's realization  upon the
collateral may  be  delayed  or  limited.  The  Portfolio  may  not  enter  into
repurchase  agreements with more  than seven days  to maturity if,  as a result,
more than  15% of  the  market value  of the  Portfolio's  net assets  would  be
invested in such repurchase agreements and in other investments for which market
quotations are not readily available or which are otherwise illiquid.
 
    WHEN-ISSUED  AND DELAYED  DELIVERY SECURITIES.   The  Portfolio may purchase
securities on a  when-issued or  delayed delivery basis.  In such  transactions,
instruments  are bought with payment and delivery  taking place in the future in
order to secure what is considered to  be an advantageous yield or price at  the
time  of the transaction. Delivery of and  payment for these securities may take
as long as a month  or more after the date  of the purchase commitment but  will
take  place  no more  than 120  days after  the trade  date. The  Portfolio will
maintain with the custodian  a separate account with  a segregated portfolio  of
cash  or liquid securities in an amount at least equal to these commitments. The
payment  obligation   and   the   interest   rates   that   will   be   received
 
                                       15
<PAGE>
are  each fixed  at the  time the  Portfolio enters  into the  commitment and no
interest accrues to the  Portfolio until settlement. Thus,  it is possible  that
the  market value at  the time of settlement  could be higher  or lower than the
purchase price if, among other factors, the general level of interest rates  has
changed.  It is a current policy of  the Portfolio not to enter into when-issued
commitments  exceeding  in  the  aggregate  15%  of  the  market  value  of  the
Portfolio's total assets less liabilities, other than the obligations created by
these commitments.
 
                             INVESTMENT LIMITATIONS
 
    The  International Magnum Portfolio is  a non-diversified investment company
under the 1940 Act, which  means that the Portfolio is  not limited by the  1940
Act  in  the  proportion  of  its  total assets  that  may  be  invested  in the
obligations of  a  single issuer.  Thus,  the  Portfolio may  invest  a  greater
proportion  of its total assets in the securities of a smaller number of issuers
and, as a result, will be subject to greater risk with respect to its respective
portfolio securities. Nevertheless,  the Portfolio  intends to  comply with  the
more  limited diversification requirements imposed  by the Internal Revenue Code
of 1986,  as amended  (the "Code"),  for qualification  as regulated  investment
companies.
 
    The  Portfolio also operates under  certain investment restrictions that are
deemed fundamental limitations and may be changed only with the approval of  the
holders  of  a  majority  of  the  Portfolio's  outstanding  shares  and certain
non-fundamental investment limitations that  may be changed without  shareholder
approval.  For  additional information  on  the fundamental  and non-fundamental
investment  limitations,  see  "Investment  Limitations"  in  the  Statement  of
Additional Information.
 
                             MANAGEMENT OF THE FUND
 
    INVESTMENT ADVISER.  Morgan Stanley Asset Management Inc. is the Adviser and
Administrator  of the  Fund and the  Portfolio. The  Adviser provides investment
advice and  portfolio management  services pursuant  to an  Investment  Advisory
Agreement  and, subject  to the  supervision of  the Fund's  Board of Directors,
makes each of the Portfolio's day-to-day investment decisions, arranges for  the
execution   of  portfolio  transactions  and   generally  manages  each  of  the
Portfolio's  investments.  The   Adviser  is  entitled   to  receive  from   the
International  Magnum  Portfolio an  annual  management fee,  payable quarterly,
equal to 0.80% of the average daily net assets of the Portfolio.
 
    The fees of the Portfolio are higher than those of most investment companies
because the Portfolio  invests internationally.  The Adviser  believes that  the
fees  are  comparable  to  those  of  other  investment  companies  that  invest
internationally. The Adviser has agreed to a reduction in the fees payable to it
and to reimburse  the Portfolio, if  necessary, if such  fees would cause  total
annual  operating expenses of the Portfolio to exceed 1.00% of the average daily
net assets of the Class A shares of the Portfolio and 1.25% of the average daily
net assets of the Class B shares of the Portfolio.
 
   
    The Adviser, with  principal offices  at 1221  Avenue of  the Americas,  New
York,  New York  10020, conducts a  worldwide portfolio  management business and
provides a broad  range of  portfolio management  services to  customers in  the
United  States and abroad.  On February 5,  1997, Morgan Stanley  Group Inc. and
Dean Witter, Discover &  Co. announced that they  had entered into an  Agreement
and  Plan of Merger to  form Morgan Stanley, Dean  Witter, Discover & Co. Morgan
Stanley Group  Inc. is  the direct  parent of  the Adviser  and Morgan  Stanley.
Subject  to certain conditions  being met, it is  currently anticipated that the
transaction will close in mid-1997.  Thereafter, the Adviser and Morgan  Stanley
will be subsidiaries of Morgan Stanley, Dean Witter, Discover & Co. At March 31,
1997,  the  Adviser, together  with its  affiliated asset  management companies,
    
 
                                       16
<PAGE>
   
managed investments totaling in excess of $118 billion, including  approximately
$100  billion  under active  management and  $18 billion  as Named  Fiduciary or
Fiduciary Adviser. See "Management of the  Fund" in the Statement of  Additional
Information.
    
 
    PORTFOLIO  MANAGER.  FRANCINE J. BOVICH.  Francine Bovich joined the Adviser
as a  Principal  in  1993.  She is  responsible  for  portfolio  management  and
communication  of  the  Adviser's  asset  allocation  strategy  to institutional
investor clients.  Previously, Ms.  Bovich was  a Principal  and Executive  Vice
President  of Westwood  Management Corp.  ("Westwood"), a  registered investment
adviser. Before  joining  Westwood, she  was  a Managing  Director  of  Citicorp
Investment  Management, Inc. (now Chancellor  Capital Management), where she was
responsible for the Institutional Investment Management group. Ms. Bovich  began
her investment career with Banker's Trust Company. She holds a B.A. in Economics
from Connecticut College and an M.B.A. in Finance from New York University.
 
    ADMINISTRATOR.   The  Adviser also  provides administrative  services to the
Fund pursuant to an  Administration Agreement. The  services provided under  the
Administration  Agreement are subject to the supervision of the Officers and the
Board of Directors of the Fund and include day-to-day administration of  matters
related  to the  corporate existence  of the  Fund, maintenance  of its records,
preparation  of  reports,  supervision  of  the  Fund's  arrangements  with  its
custodian   and  assistance  in  the  preparation  of  the  Fund's  registration
statements under federal laws. The  Administration Agreement also provides  that
the  Administrator,  through its  agents, will  provide dividend  disbursing and
transfer agent services to the Fund.  For its services under the  Administration
Agreement,  the Fund  pays the Adviser  a monthly  fee which on  an annual basis
equals 0.15% of the average daily net assets of the Portfolio.
 
   
    Under an  agreement  between  the  Adviser  and  The  Chase  Manhattan  Bank
("Chase"),  Chase provides certain  administrative services to  the Fund through
its corporate  affiliate, Chase  Global Funds  Services Company  ("CGFSC").  The
Adviser  supervises and monitors such administrative services provided by CGFSC.
Their services are also subject to the supervision of the Board of Directors  of
the  Fund. CGFSC's business address is  73 Tremont Street, Boston, Massachusetts
02108-3913.
    
 
    DIRECTORS AND OFFICERS.  Pursuant  to the Fund's Articles of  Incorporation,
the  Board of Directors decides  upon matters of general  policy and reviews the
actions of  the Fund's  Adviser, Administrator,  Distributor and  other  service
providers.  The Officers  of the Fund  conduct and supervise  its daily business
operations.
 
    DISTRIBUTOR.   Morgan Stanley  serves as  the exclusive  Distributor of  the
shares  of  the Fund.  Under its  Distribution Agreement  with the  Fund, Morgan
Stanley sells shares of the Portfolio upon the terms and at the current offering
price described in this Prospectus. Morgan Stanley is not obligated to sell  any
certain number of shares of the Fund.
 
    The  Portfolio currently offers  only the classes of  shares offered by this
Prospectus. The Portfolio may in the future offer one or more classes of  shares
with  features, distribution expenses or other  expenses that are different from
those of the classes currently offered.
 
    The Fund has  adopted a Plan  of Distribution  with respect to  the Class  B
shares  pursuant to Rule 12b-1 under the  1940 Act (the "Plan"). Under the Plan,
the Distributor is entitled  to receive from the  Portfolio a distribution  fee,
which  is accrued  daily and  paid quarterly,  of 0.25%  of the  Class B shares'
average daily net  assets on  an annualized  basis. The  Distributor expects  to
reallocate most of its fee to its investment
 
                                       17
<PAGE>
representatives.  The Distributor may, in its discretion, voluntarily waive from
time to  time all  or  any portion  of  its distribution  fee  and each  of  the
Distributor  and the Adviser is free to  make additional payments out of its own
assets to promote the  sale of Fund shares,  including payments that  compensate
financial institutions for distribution services or shareholder services.
 
    The  Plan is designed to compensate the Distributor for its services, not to
reimburse the Distributor for its expenses,  and the Distributor may retain  any
portion  of the fee that it does not expend in fulfillment of its obligations to
the Fund.
 
    EXPENSES.  The Portfolio  is responsible for payment  of certain other  fees
and  expenses  (including  legal  fees, accountants'  fees,  custodial  fees and
printing and mailing  costs) specified  in the  Administration and  Distribution
Agreements.
 
                               PURCHASE OF SHARES
 
    Class  A and Class B shares of the Portfolio may be purchased, without sales
commission, at the net  asset value per share  next determined after receipt  of
the purchase order by the Portfolio. See "Valuation of Shares."
 
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
 
    For  a Portfolio account, the minimum initial investment and minimum account
size is $500,000 for  Class A shares  and $100,000 for  Class B shares.  Certain
advisory  or asset allocation accounts, such as Total Funds Management Accounts,
managed by  Morgan Stanley  or its  affiliates including  the Adviser  ("Managed
Accounts")  may purchase  Class A shares  without being subject  to such minimum
initial investment or minimum account size requirements for a Portfolio account.
Employees of the  Adviser and  certain of its  affiliates may  purchase Class  A
shares  subject to conditions, including  a lower minimum investment established
by Officers of the Fund.
 
    If the value of  a Portfolio account containing  Class A shares falls  below
$500,000   (but   remains  at   or  above   $100,000)  because   of  shareholder
redemption(s), the Fund will  notify the shareholder, and  if the account  value
remains  below  $500,000 (but  remains at  or above  $100,000) for  a continuous
60-day period, the Class A shares in such account will convert to Class B shares
and will be subject to the distribution fee and other features applicable to the
Class B shares. The Fund,  however, will not convert Class  A shares to Class  B
shares  based solely upon changes in the  market that reduce the net asset value
of shares. Under current  tax law, conversions between  share classes are not  a
taxable event to the shareholder.
 
    Investors  may also invest in the Fund  by purchasing shares through a trust
department, broker, dealer, agent, financial planner, financial services firm or
investment adviser.  An  investor  may  be  charged  an  additional  service  or
transaction fee by that institution.
 
   
    The minimum investment levels may be waived at the discretion of the Adviser
for  (i) certain employees and customers of Morgan Stanley or its affiliates and
certain  trust  departments,  brokers,  dealers,  agents,  financial   planners,
financial  services  firms, or  investment advisers  that  have entered  into an
agreement with  Morgan  Stanley  or  its affiliates;  and  (ii)  retirement  and
deferred  compensation plans and trusts used  to fund such plans, including, but
not limited to, those defined in Section  401(a), 403(b) or 457 of the Code  and
"rabbi  trusts."  The  Fund  reserves  the  right  to  modify  or  terminate the
conversion features  of the  shares as  stated above  at any  time upon  60-days
notice to shareholders.
    
 
                                       18
<PAGE>
    The  Adviser reserves the right in its sole discretion to determine which of
such advisory  or  asset allocation  accounts  shall be  Managed  Accounts.  For
information  regarding  Managed  Accounts, please  contact  your  Morgan Stanley
account representative or the Fund at the telephone number provided on the cover
of this Prospectus.
 
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
 
    If the  value  of  a  Portfolio account  falls  below  $100,000  because  of
shareholder  redemption(s), the  Fund will  notify the  shareholder, and  if the
account value remains below $100,000 for a continuous 60-day period, the  shares
in  such account are subject to redemption by the Fund and, if redeemed, the net
asset value of such shares will be  promptly paid to the shareholder. The  Fund,
however,  will not redeem  shares based solely  upon changes in  the market that
reduce the net asset value of shares.
 
    The  Fund  reserves  the  right  to  modify  or  terminate  the  involuntary
redemption  features of  the shares  as stated  above at  any time  upon 60-days
notice to shareholders.
 
CONVERSION FROM CLASS B TO CLASS A SHARES
 
    If the value of Class B shares in a Portfolio account increases, whether due
to shareholder share  purchases or  market activity,  to $500,000  or more,  the
Class  B shares  will convert  to Class  A shares.  Under current  tax law, such
conversion is not a taxable event  to the shareholder. Class A shares  converted
from  Class B shares are  subject to the same  minimum account size requirements
that are applicable to Portfolio accounts  containing Class A shares, as  stated
above.  The  Fund reserves  the  right to  modify  or terminate  this conversion
feature at any time upon 60-days notice to shareholders.
 
INITIAL PURCHASES DIRECTLY FROM THE FUND
 
    The Fund's determination of an investor's eligibility to purchase shares  of
a  given class will  take precedence over  the investor's selection  of a class.
Assuming the investor is eligible for the  class, the Fund will select the  most
favorable class for the investor, if the investor has not done so.
 
1) BY  CHECK.   An account may  be opened  by completing and  signing an Account
   Registration Form and mailing it, together with a check ($500,000 minimum for
   Class A  shares of  the Portfolio  and $100,000  for Class  B shares  of  the
   Portfolio,  with certain exceptions  for Morgan Stanley  employees and select
   customers) payable to "Morgan Stanley Institutional Fund, Inc. --  [portfolio
   name]", to:
 
      Morgan Stanley Institutional Fund, Inc.
      P.O. Box 2798
      Boston, Massachusetts 02208-2798
   
  Payment  will  be accepted  only in  U.S. dollars,  unless prior  approval for
  payment by other currencies is given by the Fund. The classes of shares of the
  Portfolio to be  purchased should  be designated on  the Account  Registration
  Form.  For purchases  by check, the  Fund is ordinarily  credited with Federal
  Funds within  one business  day. Thus  your  purchase of  shares by  check  is
  ordinarily  credited to your account  at the net asset  value per share of the
  Portfolio determined on the next business day after receipt.
    
 
                                       19
<PAGE>
2) BY FEDERAL  FUNDS WIRE.   Purchases  may be  made by  having your  bank  wire
   Federal  Funds to the Fund's bank account.  In order to ensure prompt receipt
   of your Federal Funds Wire, it is important that you follow these steps:
 
A.  Telephone the  Fund (toll  free: 1-800-548-7786)  and provide  us with  your
    name,  address,  telephone  number, Social  Security  or  Tax Identification
    Number, the  portfolio(s) selected,  the class  selected, the  amount  being
    wired,  and by  which bank.  We will  then provide  you with  a Fund account
    number. (Investors with existing accounts should also notify the Fund  prior
    to wiring funds.)
 
B.  Instruct  your  bank  to  wire  the  specified  amount  to  the  Fund's Wire
    Concentration Bank Account (be  sure to have your  bank include the name  of
    the  portfolio(s)  selected,  the  class  selected  and  the  account number
    assigned to you) as follows:
 
   
    The Chase Manhattan Bank
    One Manhattan Plaza
    New York, NY 10081-1000
    ABA #021000021
    DDA #910-2-733293
    Attn: Morgan Stanley Institutional Fund, Inc.
    Ref: (Portfolio name, your account number, your account name)
    
 
Please call the Fund at 1-800-548-7786 prior to wiring funds.
 
C.  Complete and sign the Account Registration  Form and mail it to the  address
    shown thereon.
 
  The  purchase price of the Class A and  Class B shares of the Portfolio is the
  net asset value next determined after the order is received. See "Valuation of
  Shares." An order received prior to the  close of the New York Stock  Exchange
  ("NYSE"),  which is currently 4:00 p.m. Eastern  Time, will be executed at the
  price computed on the date  of receipt; an order  received after the close  of
  the  NYSE will be executed at  the price computed on the  next day the NYSE is
  open as long as  the Transfer Agent  receives payment by  check or in  Federal
  Funds prior to the regular close of the NYSE on such day.
 
  Federal Funds purchase orders will be accepted only on a day on which the Fund
  and Chase (the "Custodian Bank") are open for business. Your bank may charge a
  service fee for wiring Federal Funds.
 
3) BY  BANK WIRE.   The  same procedure outlined  under "By  Federal Funds Wire"
   above must be  followed in  purchasing shares  by bank  wire. However,  money
   transferred  by bank wire may or may  not be converted into Federal Funds the
   same day, depending on the time the  money is received and the bank  handling
   the  wire. Prior to such conversion, an investor's money will not be invested
   and, therefore, will not be earning dividends. Your bank may charge a service
   fee for wiring funds.
 
                                       20
<PAGE>
ADDITIONAL INVESTMENTS
 
    You  may  add to  your account  at any  time (minimum  additional investment
$1,000, except  for  automatic  reinvestment  of  dividends  and  capital  gains
distributions for which there are no minimums) by purchasing shares at net asset
value  by mailing a check to the  Fund (payable to "Morgan Stanley Institutional
Fund, Inc. -- [portfolio name]") at the above address or by wiring monies to the
Custodian Bank as outlined above. It  is very important that your account  name,
the  portfolio name and the class selected be specified in the letter or wire to
assure proper  crediting to  your account.  In order  to ensure  that your  wire
orders  are invested  promptly, you  are requested to  notify one  of the Fund's
representatives (toll-free 1-800-548-7786)  prior to the  wire date.  Additional
investments will be applied to purchase additional shares in the same class held
by a shareholder in a Portfolio account.
 
OTHER PURCHASE INFORMATION
 
    Although  the legal rights of Class A  and Class B shares will be identical,
the different expenses borne  by each class will  result in different net  asset
values  and dividends. The net  asset value of Class  B shares will generally be
lower than the net asset value of Class A shares as a result of the distribution
expense charged to Class B shares. It  is expected, however, that the net  asset
value  per share of the two classes  will tend to converge immediately after the
recording of dividends  which will  differ by  approximately the  amount of  the
distribution expense accrual differential between the classes.
 
    In  the interest  of economy and  convenience, and because  of the operating
procedures of the Fund, certificates  representing shares of the Portfolio  will
not  be issued. All shares  purchased are confirmed to  you and credited to your
account on the Fund's books  maintained by the Adviser  or its agents. You  will
have  the  same  rights  and  ownership  with  respect  to  such  shares  as  if
certificates had been issued.
 
    To ensure that checks are collected by the Fund, withdrawals of  investments
made  by check are  not presently permitted  until payment for  the purchase has
been received,  which may  take up  to eight  business days  after the  date  of
purchase.  As a condition  of this offering,  if a purchase  is cancelled due to
nonpayment or because your check does not clear, you will be responsible for any
loss the Fund or its  agents incur. If you are  already a shareholder, the  Fund
may  redeem shares from your account(s) to  reimburse the Fund or its agents for
any loss. In addition,  you may be prohibited  or restricted from making  future
investments in the Fund.
 
    Investors  may  also invest  in the  Fund by  purchasing shares  through the
Distributor.
 
EXCESSIVE TRADING
 
    Frequent  trades  involving  either   substantial  portfolio  assets  or   a
substantial  portion of your  account or accounts controlled  by you can disrupt
management of a portfolio and raise its expenses. Consequently, in the  interest
of  all the stockholders  of the Portfolio and  the Portfolio's performance, the
Fund may in its discretion bar  a stockholder that engages in excessive  trading
of  shares of any class  of a portfolio from further  purchases of shares of the
Fund for an indefinite period. The  Fund considers excessive trading to be  more
than  one purchase and sale involving shares of the same class of a portfolio of
the Fund  within  any  120-day  period. As  an  example,  exchanging  shares  of
portfolios  of  the Fund  as follows  amounts  to excessive  trading: exchanging
shares of  Portfolio A  for shares  of Portfolio  B, then  exchanging shares  of
Portfolio B for shares of Portfolio C and again exchanging shares of Portfolio C
for shares of Portfolio B within a 120-day period. Two types of transactions are
 
                                       21
<PAGE>
   
exempt from these excessive trading restrictions: (1) trades exclusively between
money  market  portfolios;  and (2)  trades  done  in connection  with  an asset
allocation service, such as TFM Accounts  or accounts managed or advised by  the
Adviser and/or any of its affiliates.
    
 
INVESTMENT IN FUNDS THROUGH A TOTAL FUNDS MANAGEMENT ("TFM") ACCOUNT
 
   
    In  addition to the considerable diversification among individual securities
you receive by investing in a particular Portfolio, you can further reduce  risk
by  spreading  your assets  among several  different  Portfolios that  each have
different  risk  and  return  characteristics.  TFM  is  an  active   investment
management service managed by Morgan Stanley or its affiliates, including Morgan
Stanley  Asset  Management Inc.  (each, a  "TFM  Adviser"), that  allocates your
investments across a combination of either Class A or Class B shares of  certain
of  the Portfolios selected to meet your long-term investment objectives as well
as, in certain circumstances, your current income objectives.
    
 
   
    The TFM Adviser has developed investment strategies for TFM Accounts to meet
the diverse financial needs of different  investors. You can open a TFM  Account
by  meeting with one  of the investment professionals  of a Participating Dealer
who will review your situation and  help you identify your long-term  investment
and/or  current income  objectives. After using  TFM criteria  to determine your
long-term investment and/or  current income  objectives, you can  choose one  of
several  TFM investment strategies. Based on  your chosen strategy, your initial
investment will be allocated among a number of the Class A or Class B shares  of
the  Portfolios. Depending  on market  conditions, the  TFM Adviser periodically
reallocates the combination of Portfolios or the percentage amounts invested  in
the  shares  of each  Portfolio to  implement your  TFM investment  strategy. In
addition, your TFM Account will be periodically rebalanced to maintain your  TFM
strategy's  current asset allocation mix, if and  when the performance of one or
more of  the Portfolios  unbalances the  strategy's mix.  You will  pay the  TFM
Adviser  a fee for the  TFM Account service that is  in addition to and separate
from the fees and expenses you will pay directly or indirectly as an investor in
the Portfolios. See "Fund Expenses."
    
 
   
    From time to time, one or more of the Portfolios used for investment by  the
TFM  Accounts may experience relatively large  investments or redemptions due to
the TFM  Account allocations  or rebalancings  recommended by  the TFM  Adviser.
These  transactions will affect the Portfolios, since Portfolios that experience
redemptions as  a result  of  reallocations or  rebalancings  may have  to  sell
portfolio  securities and Portfolios  that receive additional  cash will have to
invest it in additional portfolio securities. While it is impossible to  predict
the  overall  impact of  these transactions  over time,  there could  be adverse
effects on portfolio management to the extent that Portfolios may be required to
sell securities or invest  cash at times  when they would  not otherwise do  so.
These  transactions  could also  have tax  consequences  if sales  of securities
resulted in  gains  and could  also  increase transaction  costs.  The  Adviser,
representing  the interests  of the Portfolios,  is committed  to minimizing the
impact of TFM Account transactions on the Portfolios. The Adviser, however, will
have a conflict in fulfilling  this responsibility in that  it also serves as  a
TFM  Adviser. In that  capacity, the Adviser, representing  the interests of the
TFM Accounts,  also  is  committed  to minimizing  the  impact  of  TFM  Account
transactions  on  the  Portfolios to  the  extent consistent  with  pursuing the
investment objectives of the TFM Accounts. In addition, an affiliate of the  TFM
Adviser,  the Distributor is compensated on the sale, and may be compensated for
distribution or shareholder services  on the sale of  shares of the  Portfolios.
See  "Purchase of Shares"  and "Shareholder Services  -- Exchange Features." The
Adviser will monitor the impact of TFM Account transactions on the Portfolios.
    
 
                                       22
<PAGE>
                              REDEMPTION OF SHARES
 
    You may  withdraw all  or  any portion  of the  amount  in your  account  by
redeeming  shares at any time. Please note  that purchases made by check are not
permitted to be redeemed until payment of the purchase price has been collected,
which may take up to  eight business days after  purchase. The Fund will  redeem
Class  A shares or  Class B shares of  the Portfolio at  the next determined net
asset value of shares of  the applicable class. On days  that both the NYSE  and
the  Custodian Bank are open for business, the  net asset value per share of the
Portfolio is determined at the close of trading of the NYSE (currently 4:00 p.m.
Eastern Time). Shares of the Portfolio may be redeemed by mail or telephone.  No
charge  is made for redemption. Any redemption proceeds may be more or less than
the purchase price of your shares depending on, among other factors, the  market
value of the investment securities held by the Portfolio.
 
BY MAIL
 
    The  Portfolio will redeem its  Class A shares or Class  B shares at the net
asset value determined on the  date the request is  received, if the request  is
received  in "good  order" before  the regular close  of the  NYSE. Your request
should be addressed to Morgan Stanley  Institutional Fund, Inc., P.O. Box  2798,
Boston,  MA 02208-2798,  except that deliveries  by overnight  courier should be
addressed to Morgan  Stanley Institutional  Fund, Inc., c/o  Chase Global  Funds
Services Company, 73 Tremont Street, Boston, MA 02108-3913.
 
    "Good  order"  means that  the  request to  redeem  shares must  include the
following documentation:
 
             (a) A letter of  instruction or a  stock assignment specifying  the
class  and  number of  shares or  dollar amount  to be  redeemed, signed  by all
registered owners of the shares in the exact names in which they are registered;
 
            (b) Any  required  signature  guarantees  (see  "Further  Redemption
Information" below); and
 
             (c)  Other supporting legal documents, if  required, in the case of
estates,  trusts,  guardianships,  custodianships,  corporations,  pension   and
profit-sharing plans and other organizations.
 
    Shareholders who are uncertain of requirements for redemption should consult
with a Fund representative.
 
BY TELEPHONE
 
    Provided  you have previously elected the Telephone Redemption Option on the
Account Registration  Form, you  can  request a  redemption  of your  shares  by
calling  the Fund  and requesting  the redemption proceeds  be mailed  to you or
wired to your  bank. Please contact  one of Fund's  representatives for  further
details.  In times of drastic market conditions, the telephone redemption option
may be  difficult  to  implement.  If you  experience  difficulty  in  making  a
telephone  redemption, your request may  be made by mail  or express mail and it
will be implemented at the net asset value next determined after it is received.
Redemption requests sent to the Fund through express mail must be mailed to  the
address  of the  Dividend Disbursing  and Transfer  Agent listed  under "General
Information." The Fund and the Fund's transfer agent (the "Transfer Agent") will
employ reasonable procedures  to confirm that  the instructions communicated  by
telephone  are  genuine.  These  procedures include  requiring  the  investor to
provide certain personal identification  information at the  time an account  is
opened  and  prior  to effecting  each  transaction requested  by  telephone. In
addition, all telephone transaction requests
 
                                       23
<PAGE>
will be recorded and investors may be required to provide additional  telecopied
written  instructions regarding transaction  requests. Neither the  Fund nor the
Transfer Agent will be responsible for any loss, liability, cost or expense  for
following  instructions  received by  telephone that  either of  them reasonably
believes to be genuine.
 
    To change the commercial  bank or account  designated to receive  redemption
proceeds,  a written  request must  be sent  to the  Fund at  the address above.
Requests to change the bank  or account must be  signed by each shareholder  and
each signature must be guaranteed.
 
FURTHER REDEMPTION INFORMATION
 
    Normally  the  Fund will  make payment  for all  shares redeemed  within one
business day of receipt  of the request,  but in no event  will payment be  made
more  than  seven days  after receipt  of  a redemption  request in  good order.
However, payments to investors  redeeming shares which  were purchased by  check
will  not be made until  payment for the purchase  has been collected, which may
take up to eight days after the date of purchase. The Fund may suspend the right
of redemption or postpone the date upon which redemptions are effected at  times
when  the NYSE is closed, or under  any emergency circumstances as determined by
the Securities and Exchange Commission (the "Commission").
 
    If the Board  of Directors determines  that it would  be detrimental to  the
best  interests of the  remaining shareholders of the  Portfolio to make payment
wholly or partly in cash, the Fund  may pay the redemption proceeds in whole  or
in part by a distribution in-kind of securities held by the Portfolio in lieu of
cash    in    conformity   with    applicable    rules   of    the   Commission.
Distributions-in-kind will be made  in readily marketable securities.  Investors
may  incur brokerage charges on the sale  of portfolio securities so received in
payment of redemptions.
 
    To protect  your account,  the Fund  and its  agents from  fraud,  signature
guarantees  are required for  certain redemptions to verify  the identity of the
person who has  authorized a redemption  from your account.  Please contact  the
Fund for further information.
 
                              SHAREHOLDER SERVICES
 
EXCHANGE FEATURES
 
    You  may exchange  shares that you  own in  the Portfolio for  shares of any
other available portfolio(s) of  the Fund (other  than the International  Equity
Portfolio,  which is  closed to  new investors). In  exchanging for  shares of a
portfolio with more  than one  class, the  class of  shares you  receive in  the
exchange  will be determined in the same  manner as any other purchase of shares
and will not  be based  on the  class of  shares surrendered  for the  exchange.
Consequently,  the same minimum initial investment  and minimum account size for
determining the  class  of shares  received  in  the exchange  will  apply.  See
"Purchase  of Shares."  Shares of  the portfolios  may be  exchanged by  mail or
telephone. The privilege to exchange shares  by telephone is automatic and  made
available  without shareholder election. Before you make an exchange, you should
read the prospectus of the portfolio(s) in which you seek to invest. Because  an
exchange  transaction  is treated  as a  redemption followed  by a  purchase, an
exchange would be considered  a taxable event for  shareholders subject to  tax.
The  exchange privilege may  be modified or  terminated by the  Fund at any time
upon 60 days notice to shareholders.
 
                                       24
<PAGE>
BY MAIL
 
    In order to  exchange shares  by mail, you  should include  in the  exchange
request  the name,  class of  shares and  account number  of the  Portfolio, the
name(s) of the  portfolio(s) and class(es)  of shares into  which you intend  to
exchange  shares, and the signatures of all registered account holders. Send the
exchange request  to Morgan  Stanley Institutional  Fund, Inc.,  P.O. Box  2798,
Boston, Massachusetts 02208-2798.
 
BY TELEPHONE
 
   
    When  exchanging shares by  telephone, have ready the  name, class of shares
and account number of your current Portfolio, the names of the portfolio(s)  and
class(es)  of  shares into  which  you intend  to  exchange shares,  your Social
Security number  or Tax  I.D. number,  and your  account address.  Requests  for
telephone  exchanges received prior to 4:00 p.m. (Eastern Time) are processed at
the close of business that same day based on the net asset value of the class of
the portfolios involved  in the  exchange of shares  at the  close of  business.
Requests  received after 4:00 p.m. are processed  the next business day based on
the net  asset value  determined  at the  close of  business  on such  day.  For
additional   information  regarding  responsibility   for  the  authenticity  of
telephoned instructions, see "Redemption of Shares -- By Telephone" above.
    
 
TRANSFER OF REGISTRATION
 
    You may transfer the registration of any of your Portfolio shares to another
person by writing  to Morgan Stanley  Institutional Fund, Inc.,  P.O. Box  2798,
Boston,  MA 02208-2798. As in the case  of redemptions, the written request must
be received in  good order  before any transfer  can be  made. Transferring  the
registration  of shares may affect  the eligibility of your  account for a given
class of the  Portfolio's shares  and may  result in  involuntary conversion  or
redemption of your shares. See "Purchase of Shares" above.
 
                              VALUATION OF SHARES
 
   
    The  net asset  value per  share of a  class of  shares of  the Portfolio is
determined by dividing the total market value of the Portfolio's investments and
other assets attributable to  such class, less  any liabilities attributable  to
such  class, by  the total  number of  outstanding shares  of each  class of the
Portfolio. Net  asset value  is  calculated separately  for  each class  of  the
Portfolio.  Net asset value per share is determined  as of the close of the NYSE
on each day  that the NYSE  is open  for business. Price  information on  listed
securities  is taken from  the exchange where the  security is primarily traded.
Securities listed on a U.S. securities exchange for which market quotations  are
available  are valued at the last quoted sale  price on the day the valuation is
made. Securities listed on a foreign exchange are valued at their closing price.
Unlisted securities and listed securities not  traded on the valuation date  for
which  market quotations are  readily available are  valued at a  price within a
range not exceeding the current asked price nor less than the current bid price.
The current bid and asked prices are determined based on the average of the  bid
and asked prices quoted on such valuation date by reputable brokers.
    
 
    Bonds and other fixed income securities are valued according to the broadest
and  most representative market,  which will ordinarily  be the over-the-counter
market. Net asset value includes interest  on fixed income securities, which  is
accrued  daily.  In addition,  bonds and  other fixed  income securities  may be
valued on the basis of prices provided by a pricing service when such prices are
believed to  reflect  the fair  market  value  of such  securities.  The  prices
provided  by a pricing service are determined without regard to bid or last sale
prices, but take into account institutional  size, trading in similar groups  of
securities and any developments related to the
 
                                       25
<PAGE>
specific securities. Securities not priced in this manner are valued at the most
recently  quoted bid price or, when  securities exchange valuations are used, at
the latest  quoted sale  price on  the day  of valuation.  If there  is no  such
reported  sale, the latest  quoted bid price will  be used. Securities purchased
with remaining maturities of 60 days or less are valued at amortized cost, if it
approximates market value. In the event that amortized cost does not approximate
market value, market prices as determined above will be used.
 
   
    The value  of other  assets  and securities  for  which quotations  are  not
readily  available (including  restricted and  unlisted foreign  securities) and
those securities for which it is inappropriate to determine prices in accordance
with the above-stated procedure are determined in good faith at fair value using
methods determined by the  Board of Directors. For  purposes of calculating  net
asset value per share, all assets and liabilities initially expressed in foreign
currencies will be translated into U.S. dollars at the mean of the bid and asked
price of such currencies against the U.S. dollar last quoted by any major bank.
    
 
    Although  the legal rights of Class A  and Class B shares will be identical,
the different expenses borne  by each class will  result in different net  asset
values  and dividends for the class.  Dividends will differ by approximately the
amount of the distribution expense  accrual differential among the classes.  The
net  asset value of  Class B shares will  generally be lower  than the net asset
value of the Class A shares as  a result of the distribution expense charged  to
Class B shares.
 
                            PERFORMANCE INFORMATION
 
    The  Fund may from time to time advertise total return for each class of the
Portfolio. THESE FIGURES ARE BASED ON  HISTORICAL EARNINGS AND ARE NOT  INTENDED
TO INDICATE FUTURE PERFORMANCE.
 
    "Total  return" shows what an  investment in a class  of the Portfolio would
have earned over a specified  period of time (such as  one, five or ten  years),
assuming  that all distributions and dividends  by the Portfolio were reinvested
in the same class on the reinvestment dates during the period. Total return does
not take into account any federal or  state income taxes that may be payable  on
dividends  and  distributions  or  on  redemption.  The  Fund  may  also include
comparative performance information in advertising or marketing the  Portfolio's
shares,  including data  from Lipper  Analytical Services,  Inc., other industry
publications, business periodicals, rating services and market indices.
 
    The performance figures  for Class  B shares  will generally  be lower  than
those  for Class  A shares because  of the  distribution fee charged  to Class B
shares.
 
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
 
    All income dividends and capital gains  distributions for a class of  shares
will be automatically reinvested in additional shares of such class at net asset
value,  except that,  upon written  notice to  the Fund  or by  checking off the
appropriate box in the Distribution  Option Section on the Account  Registration
Form,  a shareholder  may elect  to receive  income dividends  and capital gains
distributions in cash.
 
   
    The Portfolio expects  to distribute  substantially all of  its taxable  net
investment  income in the form of  annual dividends. Net realized capital gains,
if any, after reduction  for any available tax  loss carryforwards will also  be
distributed annually.
    
 
                                       26
<PAGE>
    Undistributed  net  investment income  is  included in  the  Portfolio's net
assets for the purpose of calculating  net asset value per share. Therefore,  on
the  "ex-dividend" date,  the net  asset value  per share  excludes the dividend
(i.e., is  reduced by  the per  share amount  of the  dividend). Dividends  paid
shortly after the purchase of shares by an investor, although in effect a return
of capital, are taxable to shareholders subject to income tax.
 
    Because  of  the  distribution  fee  and  any  other  expenses  that  may be
attributable to  the Class  B shares,  the net  income attributable  to and  the
dividends  payable  on  Class  B  shares  will  be  lower  than  the  net income
attributable to and the dividends  payable on Class A  shares. As a result,  the
net  asset value per share of the classes of the Portfolio will differ at times.
Expenses of the  Portfolio allocated  to a particular  class of  shares will  be
borne on a pro rata basis by each outstanding share of that class.
 
                                     TAXES
 
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
 
    No  attempt has been made to present  a detailed explanation of the federal,
state, or  local income  tax treatment  of the  Portfolio or  its  shareholders.
Accordingly,  shareholders  are urged  to consult  their tax  advisers regarding
specific questions as to federal, state and local income taxes.
 
    The Portfolio  is  treated as  a  separate  entity for  federal  income  tax
purposes  and is  not combined with  the Fund's other  portfolios. The Portfolio
intends to qualify for the  special tax treatment afforded regulated  investment
companies under Subchapter M of the Code, so that the Portfolio will be relieved
of  federal income tax on that part of its net investment income and net capital
gain that is distributed to shareholders.
 
   
    The Portfolio intends  to distribute  substantially all of  its taxable  net
investment  income (including, for this purpose, net short-term capital gain) to
shareholders. Dividends from the Portfolio's  net investment income are  taxable
to  shareholders as ordinary  income, whether received in  cash or reinvested in
additional shares.  Such dividends  paid  by the  Portfolio will  generally  not
qualify for the 70% dividends-received deduction for corporate shareholders. The
Portfolio will report annually to its shareholders the amount of dividend income
qualifying for such treatment.
    
 
    Distributions  of  net capital  gain (i.e.,  net  long-term capital  gain in
excess of  net  short-term  capital  losses)  are  taxable  to  shareholders  as
long-term  capital gain,  regardless of  how long  the shareholder  has held the
Portfolio's shares. The Portfolio will send reports annually to shareholders  of
the  federal income  tax status of  all distributions made  during the preceding
year.
 
    The  Portfolio   intends  to   make  sufficient   distributions  or   deemed
distributions  of its ordinary income and capital gain net income (the excess of
short-term and  long-term capital  gain over  short-term and  long-term  capital
losses,  including any available capital loss carryforwards) prior to the end of
each calendar year to avoid liability for federal excise tax.
 
    Dividends and  other distributions  declared by  the Portfolio  in  October,
November or December of any year and payable to shareholders of record on a date
in  such month will be deemed to have been paid by the Portfolio and received by
the shareholders in that year if the distributions are paid by the Portfolio  at
any time during the following January.
 
                                       27
<PAGE>
   
    The  Fund may be required to withhold and  remit to the U.S. Treasury 31% of
any dividends, capital gains distributions  and redemption proceeds paid to  any
individual  or certain  other non-corporate  shareholder (1)  who has  failed to
provide a  correct taxpayer  identification  number (generally  an  individual's
social  security number  or non-individual's employer  identification number) on
the Application Form, (2) who is  subject to backup withholding by the  Internal
Revenue  Service, or (3) who has not certified to the Fund that such shareholder
is not  subject  to  backup  withholding. This  backup  withholding  is  not  an
additional   tax,  and  any  amounts  withheld   may  be  credited  against  the
shareholder's ultimate U.S. tax liability.
    
 
    The sale, exchange or  redemption of shares will  result in taxable gain  or
loss to the selling, exchanging or redeeming shareholder, depending upon whether
the fair market value of the sale, exchange or redemption proceeds exceed or are
less  than the shareholder's  adjusted basis in the  sold, exchanged or redeemed
shares. If capital gain distributions have been made with respect to shares that
are sold at a  loss after being held  for six months or  less, then the loss  is
treated  as  a  long-term  capital  loss  to  the  extent  of  the  capital gain
distributions.
 
    Conversion  of  shares  between  classes  are  not  taxable  events  to  the
shareholder.
 
    Shareholders  are urged  to consult with  their tax  advisers concerning the
application of state  and local income  taxes to investments  in the  Portfolio,
which may differ from the federal income tax consequences described above.
 
    Investment  income  received by  the Portfolio  from sources  within foreign
countries may be subject to foreign income taxes withheld at the source. To  the
extent  that the Portfolio is  liable for foreign income  taxes so withheld, the
Portfolio intends to operate so as to meet the requirements of the Code to  pass
through  to the shareholders credit for  foreign income taxes paid. Although the
Portfolio intends to  meet Code  requirements to  pass through  credit for  such
taxes, there can be no assurance that the Portfolio will be able to do so.
 
    THE TAX DISCUSSION SET FORTH ABOVE IS INCLUDED FOR GENERAL INFORMATION ONLY.
PROSPECTIVE  INVESTORS SHOULD CONSULT THEIR OWN TAX ADVISERS WITH RESPECT TO THE
TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN THE PORTFOLIO.
 
                             PORTFOLIO TRANSACTIONS
 
    The Adviser selects the brokers or  dealers that will execute the  purchases
and  sales  of investment  securities  for each  of  the Fund's  portfolios. The
Adviser seeks the best execution of all portfolio transactions. A portfolio  may
pay  higher commission rates than the lowest available when the Adviser believes
it is reasonable to do  so in light of the  value of the research,  statistical,
and pricing services provided by the broker effecting the transaction.
 
    It is not the Fund's practice to allocate brokerage or principal business on
the  basis of sales of shares which  may be made through intermediary brokers or
dealers. However, the Adviser may,  consistent with NASD rules, place  portfolio
orders  with qualified broker-dealers who  recommend the applicable portfolio to
their clients or who act  as agents in the purchase  of shares of the  portfolio
for their clients.
 
    Subject  to  the overriding  objective of  obtaining  the best  execution of
orders, the  Fund may  use broker-dealer  affiliates of  the Adviser,  including
Morgan  Stanley,  to effect  portfolio  brokerage transactions  under procedures
adopted by the Fund's Board of Directors. For such transactions, the  commission
rates and other
 
                                       28
<PAGE>
remuneration  paid  to  Morgan Stanley  or  other  affiliates must  be  fair and
reasonable in  comparison  to  those  of  other  broker-dealers  for  comparable
transactions  involving  similar securities  being  purchased or  sold  during a
comparable time period.
 
PORTFOLIO TURNOVER
 
    The Portfolio generally  does not  invest for  short-term trading  purposes,
however,   when  circumstances  warrant,  the   Portfolio  may  sell  investment
securities without regard  to the  length of time  they have  been held.  Market
conditions  in a given year could result in a higher or lower portfolio turnover
rate than expected and the Portfolio will not consider portfolio turnover rate a
limiting factor in  making investment decisions  consistent with its  respective
objective   and  policies.  As  portfolio   turnover  increases,  the  Portfolio
necessarily  will  experience   increased  transaction   costs  and   additional
realization of capital gains.
 
                              GENERAL INFORMATION
 
DESCRIPTION OF COMMON STOCK
 
   
    The  Fund was  organized as  a Maryland  corporation on  June 16,  1988. The
Articles of Incorporation, as amended and restated, permit the Fund to issue  up
to  35 billion shares of common stock,  with $.001 par value per share. Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number of shares the  Fund is authorized  to issue without  the approval of  the
shareholders  of the Fund. The Board of Directors has the power to designate one
or more classes of  shares of common  stock and to  classify and reclassify  any
unissued shares with respect to such classes. The shares of common stock of each
portfolio  are currently classified into two classes, the Class A shares and the
Class B  shares,  except for  the  International  Small Cap,  Money  Market  and
Municipal Money Market Portfolios which offer only Class A shares.
    
 
    The shares of the Portfolio, when issued, will be fully paid, nonassessable,
fully  transferable and redeemable at the option  of the holder. The shares have
no preference  as  to  conversion,  exchange,  dividends,  retirement  or  other
features  and  have no  pre-emptive  rights. The  shares  of the  Portfolio have
non-cumulative voting rights, which means that  the holders of more than 50%  of
the  shares voting for the election of Directors can elect 100% of the Directors
if they choose  to do so.  Persons or organizations  owning 25% or  more of  the
outstanding  shares of the Portfolio may be  presumed to "control" (as that term
is defined in the 1940 Act) the  Portfolio. Under Maryland law, the Fund is  not
required  to hold an annual meeting of its shareholders unless required to do so
under the 1940 Act.
 
REPORTS TO SHAREHOLDERS
 
    The Fund will send to its  shareholders annual and semi-annual reports;  the
financial  statements  appearing in  annual reports  are audited  by independent
accountants. Monthly unaudited portfolio  data is also  available from the  Fund
upon request.
 
    In  addition, the Adviser or its agent, as Transfer Agent, will send to each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
 
CUSTODIAN
 
    Chase is the Fund's custodian for domestic and certain foreign assets. Chase
is not an  affiliate of  the Adviser or  the Distributor.  Morgan Stanley  Trust
Company,   Brooklyn,   New  York   ("MSTC"),   an  affiliate   of   the  Adviser
 
                                       29
<PAGE>
and the Distributor, acts  as the Fund's custodian  for assets held outside  the
United  States and employs  subcustodians approved by the  Board of Directors of
the  Fund  in  accordance  with  regulations  of  the  Securities  and  Exchange
Commission for the purpose of providing custodial services for such assets. MSTC
may  also hold certain domestic assets for the Fund. For more information on the
custodians, see "General Information --  Custody Arrangements" in the  Statement
of Additional Information.
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
    Chase   Global   Funds  Services   Company,   73  Tremont   Street,  Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
 
INDEPENDENT ACCOUNTANTS
 
   
    Price Waterhouse  LLP serves  as independent  accountants for  the Fund  and
audits its annual financial statements.
    
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       30
<PAGE>
   MORGAN STANLEY INSTITUTIONAL FUND, INC.
  INTERNATIONAL MAGNUM PORTFOLIO
   P.O. BOX 2798, BOSTON, MA 02208-2798
 
                           ACCOUNT REGISTRATION FORM
 
<TABLE>
<C>   <S>                                            <C>
      ACCOUNT INFORMATION                            If you need assistance in filling out this form for the Morgan Stanley
      Fill in where applicable                       Institutional Fund, please contact your Morgan Stanley representative
                                                     or call us toll free 1-(800)-548-7786. Please print all items except
                                                     signature, and mail to the Fund at the address above.
  A)  REGISTRATION
      1. INDIVIDUAL
      2. JOINT TENANTS
         (RIGHTS OF SURVIVORSHIP PRESUMED UNLESS
         TENANCY IN COMMON
         IS INDICATED)
</TABLE>
 
1.
         First Name    Initial         Last Name
2.
         First Name    Initial         Last Name
         First Name    Initial         Last Name
 
<TABLE>
<C>   <S>                                            <C>
      3. CORPORATIONS,
         TRUSTS AND OTHERS
         Please call the Fund for additional
      documents that may be required to set up
      account and to authorize transactions.
</TABLE>
 
3.
 
<TABLE>
<S>                     <C>                 <C>                   <C>               <C>
Type of Registration:   / / INCORPORATED    / / UNINCORPORATED    / / PARTNERSHIP   / / UNIFORM GIFT/TRANSFER TO MINOR
                                            ASSOCIATION                               (ONLY ONE CUSTODIAN AND MINOR PERMITTED)
</TABLE>
 
/ / TRUST ________________________  / / OTHER (Specify) ________________________
 
<TABLE>
<C>   <S>                                            <C>
  B)  MAILING ADDRESS
      Please fill in completely, including
      telephone number(s).
</TABLE>
 
/ / United States Citizen  / / Resident Alien
                   Street or P.O. Box
                   City
                   State                   Zip
Home Telephone No.                   Business Telephone No.
/ / Non-Resident Alien:
Permanent Address (Where you reside permanently for tax purposes)
                   Street Address
                   City
                   Country                   Postal Code
Home Telephone No.                    Business Telephone No.
 
Current Mailing Address (If different from Permanent Address)
                   Street Address
                   City
                   Country
Postal Code
Home Telephone No.                   Business Telephone No.
 
<TABLE>
<C>   <S>                                            <C>                                  <C>
  C)  TAXPAYER                                       Enter   your  Taxpayer   Identification  Number.   For  most  individual
      IDENTIFICATION                                 taxpayers, this is your Social Security Number.
      NUMBER
      1. INDIVIDUAL
      2.   JOINT TENANTS
           (RIGHTS OF SURVIVORSHIP PRESUMED UNLESS
           TENANCY IN COMMON
           IS INDICATED)
      For Custodian account
      of a minor (Uniform
      Gifts/Transfers to Minor
      Acts), give the Social
      Security Number of
      the minor
                                                                                          OR
                                                     1.         TAXPAYER IDENTIFICATION                      SOCIAL SECURITY
                                                     NUMBER ("TIN")                                NUMBER ("SSN")
                                                                                              OR
                                                     2.                                                          TIN
                                                                                                                             SSN
                                                                                              OR
                                                     TIN
                                                                                                                             SSN
                                                     IMPORTANT TAX INFORMATION
                                                     You  (as a payee) are required by law to provide us (as payer) with your
                                                     correct TIN(s)  or SSN(s).  Accounts that  have a  missing or  incorrect
                                                     TIN(s)  or SSN(s) will be subject to backup withholding at a 31% rate on
                                                     dividends, distributions and other payments. If you have not provided us
                                                     with your correct TIN(s) or SSN(s), you may be subject to a $50  penalty
                                                     imposed by the Internal Revenue Service.
                                                     Backup  withholding  is  not an  additional  tax; the  tax  liability of
                                                     persons subject to backup withholding will  be reduced by the amount  of
                                                     tax  withheld.  If withholding  results in  an  overpayment of  taxes, a
                                                     refund may be obtained.
                                                     You may be  notified that you  are subject to  backup withholding  under
                                                     Section  3406(a)(1)(C)  of the  Internal Revenue  Code because  you have
                                                     underreported interest or dividends or you were required to, but  failed
                                                     to,  file a  return which would  have included a  reportable interest or
                                                     dividend payment.
</TABLE>
 
<PAGE>
 
   
<TABLE>
<C>   <S>                                  <C>                             <C>                   <C>
  D)  PORTFOLIO AND                        For Purchase of the following   / / Class A Shares $  / / Class B Shares $
      CLASS SECTION                        Portfolio:
      (Class A shares minimum $500,000     International Magnum Portfolio
      for the Portfolio and Class B
      shares minimum $100,000 for the
      Portfolio). Please indicate class
      and amount.
                                                                           Total Initial Investment $
</TABLE>
    
 
<TABLE>
<C>   <S>                        <C>
  E)  METHOD OF
      INVESTMENT
      Please indicate
      portfolio, manner of
      payment.
</TABLE>
 
Payment by:
 
/ / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND,
INC.--PORTFOLIO NAME)
 
<TABLE>
<S>                                                                          <C>
/ / Exchange $ From                                                                     -- - - - - - - - - - -- - -
                            Name of Portfolio                                                   Account No.
/ / Account previously established by:  / / Phone exchange  / / Wire on                 -- - - - - - - - - - -- - -
                                                                                      Account No.               (Check
                                                                                (Previously assigned by the Fund)     Digit)
                                                                                                                          Date
</TABLE>
 
<TABLE>
<C>   <S>                        <C>
  F)  DISTRIBUTION               Income dividends and capital gains distributions (if any) to
      OPTION                     be reinvested in additional shares unless either box below
                                 is checked.
                                 / / Income dividends to be paid in cash, capital gains
                                 distributions (if any) in shares.
                                 / / Income dividends and capital gains distributions (if
                                 any) to be paid in cash.
</TABLE>
 
<TABLE>
<C>   <S>                             <C>                                       <C>
  G)  TELEPHONE                       / / I/we hereby authorize the Fund and
      REDEMPTION                      its agents to honor any telephone         Name of COMMERCIAL Bank (Not Savings
      AND EXCHANGE                    requests to wire redemption proceeds to   Bank)
      OPTION                          the commercial bank indicated at right    Bank Account No.
      Please select at time of        and/or mail redemption proceeds to the
      initial application if you      name and address in which my/our fund
      wish to redeem or exchange      account is registered if such requests                                        Bank
      shares by telephone. A          are believed to be authentic.                                                  ABA
      SIGNATURE GUARANTEE IS          The Fund and the Fund's Transfer Agent                                         No.
      REQUIRED IF BANK ACCOUNT IS     will employ reasonable procedures to
      NOT REGISTERED IDENTICALLY TO   confirm that instructions communicated    Name(s) in which your BANK Account is
      YOUR FUND ACCOUNT.              by telephone are genuine. These           Established
      TELEPHONE REQUESTS FOR          procedures include requiring the
      REDEMPTIONS OR EXCHANGE WILL    investor to provide certain personal      Bank's Street
      NOT BE HONORED UNLESS THE BOX   identification information at the time    Address
      IS CHECKED.                     an account is opened and prior to
                                      effecting each transaction requested by   City  State  Zip
                                      telephone. In addition, all telephone
                                      transaction requests will be recorded
                                      and investors may be required to provide
                                      additional telecopied written
                                      instructions of transaction requests.
                                      Neither the Fund nor the Transfer Agent
                                      will be responsible for any loss,
                                      liability, cost or expense for following
                                      instructions received by telephone that
                                      it reasonably believes to be genuine.
</TABLE>
 
   
<TABLE>
<C>   <S>                                  <C>
  H)  INTERESTED PARTY
      OPTION                                                                                                Name
      In addition to the account
      statement sent to my/our registered
      address, I/we hereby authorize the                                                                   Address
      Fund to mail duplicate statements
      to the name and address provided at  City         State         Zip Code
      right.
</TABLE>
    
 
<TABLE>
<C>   <S>                                  <C>
  I)  DEALER
      INFORMATION
                                           Representative Name              Representative No.             Branch
                                           No.
</TABLE>
 
<TABLE>
<C>   <S>                                  <C>
  J)  SIGNATURE OF
      ALL HOLDERS
      AND TAXPAYER
      CERTIFICATION
      Sign Here ,
</TABLE>
 
<TABLE>
<S>                                  <C>
The undersigned certify that I/we have full authority and legal capacity
to purchase and redeem shares of the Fund and affirm that I/we have
received a current Prospectus of the Morgan Stanley Institutional Fund,
Inc. and agree to be bound by its terms.
  BY SIGNING THIS  APPLICATION, I/WE HEREBY  CERTIFY UNDER PENALTIES  OF
PERJURY THAT THE INFORMATION ON THIS APPLICATION IS COMPLETE AND CORRECT
AND  THAT  AS REQUIRED  BY FEDERAL  LAW  (PLEASE CHECK  APPLICABLE BOXES
BELOW):
 
/ / U.S. CITIZEN(S)/TAXPAYER(S):
 
      / / I/WE CERTIFY THAT (1)  THE NUMBER(S) SHOWN ABOVE ON THIS  FORM
          IS/ARE  THE  CORRECT SSN(S)  OR TIN(S)  AND  (2) I/WE  ARE NOT
          SUBJECT TO ANY BACKUP WITHHOLDING EITHER BECAUSE (A) I/WE  ARE
          EXEMPT  FROM  BACKUP  WITHHOLDING;  (B)  I/WE  HAVE  NOT  BEEN
          NOTIFIED BY THE INTERNAL REVENUE SERVICE ("IRS") THAT I/WE ARE
          SUBJECT TO  BACKUP WITHHOLDING  AS A  RESULT OF  A FAILURE  TO
          REPORT  ALL INTEREST OR DIVIDENDS; OR (C) THE IRS HAS NOTIFIED
          ME/US  THAT  I   AM/WE  ARE  NO   LONGER  SUBJECT  TO   BACKUP
          WITHHOLDING.
 
      / / IF NO TIN(S) OR SSN(S) HAS/HAVE BEEN PROVIDED ABOVE, I/WE HAVE
          APPLIED, OR INTEND TO APPLY, TO THE IRS OR THE SOCIAL SECURITY
          ADMINISTRATION  FOR A TIN OR A SSN AND I/WE UNDERSTAND THAT IF
          I/ WE  DO NOT  PROVIDE  EITHER NUMBER  TO CHASE  GLOBAL  FUNDS
          SERVICES  COMPANY ("CGFSC") WITHIN 60 DAYS OF THE DATE OF THIS
          APPLICATION OR IF I/WE FAIL  TO FURNISH MY/OUR CORRECT  SSN(S)
          OR  TIN(S), I/WE MAY BE SUBJECT TO  A PENALTY AND A 31% BACKUP
          WITHHOLDING ON DISTRIBUTIONS AND REDEMPTION PROCEEDS.  (PLEASE
          PROVIDE  EITHER NUMBER ON IRS FORM  W-9). YOU MAY REQUEST SUCH
          FORM BY CALLING CGFSC AT 800-282-4404.
 
/ / NON-U.S. CITIZEN(S)/TAXPAYER(S)
  UNDER PENALTIES  OF  PERJURY, I/WE  CERTIFY  THAT I/WE  ARE  NOT  U.S.
CITIZENS  OR RESIDENTS AND I/WE ARE EXEMPT FOREIGN PERSONS AS DEFINED BY
THE INTERNAL REVENUE SERVICE.
 
THE INTERNAL  REVENUE  SERVICE DOES  NOT  REQUIRE YOUR  CONSENT  TO  ANY
PROVISION  OF THIS  DOCUMENT OTHER  THAN THE  CERTIFICATIONS REQUIRED TO
AVOID BACKUP WITHHOLDING.
 
                                     (X)
(X)                                  Signature (if joint account, both
Signature                        Date must sign)      Date
</TABLE>
<PAGE>
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
- -------------------------------------------
 
  NO  DEALER, SALES  REPRESENTATIVE OR ANY  OTHER PERSON HAS  BEEN AUTHORIZED TO
GIVE ANY INFORMATION OR TO MAKE ANY REPRESENTATIONS, OTHER THAN THOSE  CONTAINED
IN THIS PROSPECTUS, IN CONNECTION WITH THE OFFER MADE BY THIS PROSPECTUS AND, IF
GIVEN OR MADE, SUCH OTHER INFORMATION OR REPRESENTATIONS MUST NOT BE RELIED UPON
AS  HAVING BEEN AUTHORIZED BY THE FUND  OR THE DISTRIBUTOR. THIS PROSPECTUS DOES
NOT CONSTITUTE AN OFFER BY THE FUND OR THE DISTRIBUTOR TO SELL OR A SOLICITATION
OF AN OFFER TO BUY ANY OF  THE SECURITIES OFFERED HEREBY IN ANY JURISDICTION  TO
ANY  PERSON TO WHOM  IT IS UNLAWFUL TO  MAKE SUCH OFFER  OR SOLICITATION IN SUCH
JURISDICTION.
 
                           --------------------------
 
                               TABLE OF CONTENTS
 
   
<TABLE>
<S>                                                 <C>
                                                    PAGE
                                                    ----
Fund Expenses.....................................    2
Prospectus Summary................................    6
Investment Objective and Policies.................   10
Additional Investment Information.................   11
Investment Limitations............................   16
Management of the Fund............................   16
Purchase of Shares................................   18
Redemption of Shares..............................   23
Shareholder Services..............................   24
Valuation of Shares...............................   25
Performance Information...........................   26
Dividends and Capital Gains Distributions.........   26
Taxes.............................................   27
Portfolio Transactions............................   28
General Information...............................   29
Account Registration Form
</TABLE>
    
 
                         INTERNATIONAL MAGNUM PORTFOLIO
 
                               A PORTFOLIO OF THE
 
                                 MORGAN STANLEY
 
                            INSTITUTIONAL FUND, INC.
 
                                  Common Stock
                               ($.001 PAR VALUE)
 
                                 -------------
                                   PROSPECTUS
                                 -------------
 
                               Investment Adviser
                                 Morgan Stanley
                             Asset Management Inc.
 
                                  Distributor
                              Morgan Stanley & Co.
                                  Incorporated
 
                                 MORGAN STANLEY
                            INSTITUTIONAL FUND, INC.
                      P.O. BOX 2798, BOSTON, MA 02208-2798
 
- ---------------------------------------
- ---------------------------------------
- ---------------------------------------
- ---------------------------------------
<PAGE>
- --------------------------------------------------------------------------------
                              P R O S P E C T U S
     ----------------------------------------------------------------------
 
                              TECHNOLOGY PORTFOLIO
 
                               A PORTFOLIO OF THE
                    MORGAN STANLEY INSTITUTIONAL FUND, INC.
 
                P.O. BOX 2798, BOSTON, MASSACHUSETTS 02208-2798
                      FOR INFORMATION CALL 1-800-548-7786
 
                                ----------------
 
    Morgan  Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company, or mutual fund, which offers redeemable shares in
a series of diversified and nondiversified investment portfolios ("portfolios").
The Fund is designed to provide clients with attractive alternatives for meeting
their investment needs.  The Fund currently  consists of twenty-nine  portfolios
representing   a  broad  range  of  investment  choices.  This  prospectus  (the
"Prospectus") pertains  to the  Class A  and Class  B shares  of the  Technology
Portfolio (the "Portfolio"). The Class A and Class B shares currently offered by
the  Portfolio have different minimum investment requirements and fund expenses.
Shares of  the portfolios  are offered  with no  sales charge,  exchange fee  or
redemption  fee, (except that the International Small Cap Portfolio may impose a
transaction fee).
 
    The Fund is designed  to meet the investment  needs of discerning  investors
who  place a premium on quality and  personal service. With Morgan Stanley Asset
Management  Inc.  as   Adviser  and   Administrator  (the   "Adviser"  and   the
"Administrator"),  and with Morgan Stanley & Co. Incorporated ("Morgan Stanley")
as Distributor, the  Fund makes available  to institutional and  high net  worth
individual  investors a series  of portfolios which  benefit from the investment
expertise and commitment to  excellence associated with  Morgan Stanley and  its
affiliates.
 
    This Prospectus is designed to set forth concisely the information about the
Fund  that a prospective investor should know  before investing and it should be
retained for future reference. The  Fund offers additional portfolios which  are
described  in other prospectuses and under  "Prospectus Summary" below. The Fund
currently offers the following portfolios:  (i) GLOBAL AND INTERNATIONAL  EQUITY
- --  Active Country Allocation, Asian  Equity, Emerging Markets, European Equity,
Global Equity, Gold, International  Equity, International Magnum,  International
Small  Cap, Japanese Equity  and Latin American Portfolios;  (ii) U.S. EQUITY --
Aggressive Equity,  Emerging  Growth, Equity  Growth,  Small Cap  Value  Equity,
Technology, U.S. Real Estate and Value Equity Portfolios; (iii) EQUITY AND FIXED
INCOME  -- Balanced Portfolio; (iv) FIXED INCOME -- Emerging Markets Debt, Fixed
Income, Global Fixed Income, High Yield  and Municipal Bond Portfolios; and  (v)
MONEY  MARKET -- Money Market and  Municipal Money Market Portfolios. Additional
information  about  the  Fund  is  contained  in  a  "Statement  of   Additional
Information,"  dated May 1, 1997, which is incorporated herein by reference. The
Statement of Additional Information and the prospectuses pertaining to the other
portfolios of the Fund are available upon request and without charge by  writing
or calling the Fund at the address and telephone number set forth above.
 
  THESE  SECURITIES HAVE NOT  BEEN APPROVED OR  DISAPPROVED BY THE SECURITIES
   AND EXCHANGE COMMISSION, NOR HAS  THE SECURITIES AND EXCHANGE  COMMISSION
    PASSED  UPON  THE ACCURACY  OR ADEQUACY  OF THIS  PROSPECTUS.       ANY
             REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.
 
                  THE DATE OF THIS PROSPECTUS IS MAY 1, 1997.
<PAGE>
                                 FUND EXPENSES
 
    The  following table illustrates all expenses and fees that a shareholder of
the Technology Portfolio will incur:
   
<TABLE>
<CAPTION>
SHAREHOLDER TRANSACTION EXPENSES
- --------------------------------------------------------------------------------------------
<S>                                                                                           <C>
Maximum Sales Load Imposed on Purchases
  Class A...................................................................................       None
  Class B...................................................................................       None
Maximum Sales Load Imposed on Reinvested Dividends
  Class A...................................................................................       None
  Class B...................................................................................       None
Deferred Sales Load
  Class A...................................................................................       None
  Class B...................................................................................       None
Redemption Fees
  Class A...................................................................................       None
  Class B...................................................................................       None
Exchange Fees
  Class A...................................................................................       None
  Class B...................................................................................       None
 
<CAPTION>
 
ANNUAL FUND OPERATING EXPENSES
- --------------------------------------------------------------------------------------------
(AS A PERCENTAGE OF AVERAGE NET ASSETS)
<S>                                                                                           <C>
Management Fee (Net of Fee Waiver)*
  Class A...................................................................................      0.00%
  Class B...................................................................................      0.00%
12b-1 Fees
  Class A...................................................................................       None
  Class B...................................................................................      0.25%
Other Expenses
  Class A...................................................................................      1.25%
  Class B...................................................................................      1.25%
                                                                                              ---------
Total Operating Expenses (Net of Fee Waivers or Expense Reimbursements)*
  Class A...................................................................................      1.25%
  Class B...................................................................................      1.50%
                                                                                              ---------
                                                                                              ---------
</TABLE>
    
 
- --------------
 
   
*The Adviser  has agreed  to  waive its  management  fees and/or  reimburse  the
 Portfolio,  if necessary, if  such fees would cause  the total annual operating
 expenses of the Portfolio  to exceed a specified  percentage of its  respective
 average  daily net assets. Absent  the fee waiver, the  management fee would be
 1.00%. Absent the  fee waivers and/or  expense reimbursements, the  Portfolio's
 total  operating expenses would be 8.51% of the average daily net assets of the
 Class A shares and 9.14% of the average daily net assets of the Class B shares.
 As a result of this  reduction, the Management Fee  stated above is lower  than
 the contractual fee stated under "Management of the Fund." The Adviser reserves
 the  right to terminate any of its fee waivers and/or expense reimbursements at
 any time in its sole discretion. For further information on Portfolio expenses,
 see "Management of the Fund."
    
 
                                       2
<PAGE>
   
    The purpose of the  table above is to  assist the investor in  understanding
the  various expenses that  an investor in  the Portfolio will  bear directly or
indirectly. Expenses and fees for the Portfolio are based on actual figures  for
the  fiscal period ended December 31, 1996. Due to the continuous nature of Rule
12b-1 fees, long term Class B shareholders  may pay more than the equivalent  of
the  maximum  front-end  sales  charges  otherwise  permitted  by  the  National
Association of Securities Dealers, Inc. ("NASD") Conduct Rules.
    
 
    The following  example illustrates  the expenses  that you  would pay  on  a
$1,000  investment assuming (1) a 5% annual rate of return and (2) redemption at
the end of each time period. As noted in the table above, the Portfolio  charges
no  redemption fees  of any kind.  The following  example is based  on the total
operating expenses of the Portfolio after fee waivers.
 
   
<TABLE>
<CAPTION>
                                                                    1 YEAR     3 YEARS     5 YEARS     10 YEARS
                                                                   ---------  ---------  -----------  -----------
<S>                                                                <C>        <C>        <C>          <C>
Technology Portfolio
  Class A........................................................  $      13  $      40   $   *        $   *
  Class B........................................................         15         47       *            *
</TABLE>
    
 
- ------------------
*Because the  Portfolio is  new, the  Fund has  not projected  expenses for  the
 Portfolio beyond the 3-year period shown.
 
    THIS  EXAMPLE SHOULD  NOT BE CONSIDERED  A REPRESENTATION OF  PAST OR FUTURE
EXPENSES OR PERFORMANCE. THE PORTFOLIO IS NEW AND ACTUAL EXPENSES MAY BE GREATER
OR LESS THAN THOSE SHOWN.
 
                                       3
<PAGE>
                              FINANCIAL HIGHLIGHTS
 
   
    The following table provides financial highlights for the Class A and  Class
B  shares for the Technology Portfolio. The audited financial highlights for the
Portfolio's shares for the fiscal period ended December 31, 1996 are included in
the Fund's financial  statements which appear  in the Fund's  December 31,  1996
Annual  Report to  Shareholders and which  are incorporated by  reference in the
Fund's Statement of Additional Information. The Portfolio's financial highlights
have been audited by Price Waterhouse  LLP, whose unqualified report thereon  is
also  incorporated  by reference  in  the Statement  of  Additional Information.
Additional information is included in the  Annual Report. The Annual Report  and
the  financial  statements  therein,  along  with  the  Statement  of Additional
Information, are available at no cost from the Fund at the address and telephone
number noted on  the cover page  of this Prospectus.  The following  information
should be read in conjunction with the financial statements and notes thereto.
    
 
                                       4
<PAGE>
   
                            THE TECHNOLOGY PORTFOLIO
    
 
   
<TABLE>
<CAPTION>
                                                                                         CLASS A        CLASS B
                                                                                      -------------  -------------
                                                                                       PERIOD FROM    PERIOD FROM
                                                                                      SEPTEMBER 16,  SEPTEMBER 16,
                                                                                        1996* TO       1996* TO
                                                                                      DECEMBER 31,   DECEMBER 31,
                                                                                          1996           1996
                                                                                      -------------  -------------
<S>                                                                                   <C>            <C>
NET ASSET VALUE, BEGINNING OF PERIOD................................................    $   10.00      $   10.00
                                                                                      -------------  -------------
INCOME FROM INVESTMENT OPERATIONS
  Net Investment Income (1).........................................................        (0.02)         (0.02)
  Net Realized and Unrealized Gain on Investments...................................         0.73           0.73
                                                                                      -------------  -------------
    Total from Investment Operations................................................         0.71           0.71
                                                                                      -------------  -------------
NET ASSET VALUE, END OF PERIOD......................................................    $   10.71      $   10.71
                                                                                      -------------  -------------
                                                                                      -------------  -------------
TOTAL RETURN........................................................................         7.10%          7.10%
                                                                                      -------------  -------------
                                                                                      -------------  -------------
RATIOS AND SUPPLEMENTAL DATA:
  Net Assets, End of Period (Thousands).............................................    $   3,595      $   1,487
  Ratio of Expenses to Average Net Assets (1).......................................         1.25%**        1.50%**
  Ratio of Net Investment Income to Average Net Assets (1)..........................        (0.70)%**       (1.00)%**
  Portfolio Turnover Rate...........................................................           77%            77%
  Average Commission Rate...........................................................    $  0.0374      $  0.0374
- ------------------------
(1) Effect of voluntary expense limitation during the period:
     Per share benefit to net investment income.....................................        $0.22          $0.19
   Ratios before expense limitation:
     Expenses to Average Net Assets.................................................         8.51%**        9.14%**
     Net Investment Income to Average Net Assets                                            (7.96)%**       (8.65)%**
</TABLE>
    
 
   
 * Commencement of operations.
    
 
   
** Annualized
    
 
                                       5
<PAGE>
                               PROSPECTUS SUMMARY
 
THE FUND
 
    The   Fund  consists  of   twenty-nine  portfolios,  offering  institutional
investors and high net  worth individual investors a  broad range of  investment
choices coupled with the advantages of a no-load mutual fund with Morgan Stanley
and  its affiliates providing customized  services as Adviser, Administrator and
Distributor.  Each  portfolio  offers  Class  A  shares  and,  except  for   the
International  Small Cap,  Money Market  and Municipal  Money Market Portfolios,
also offers Class B shares. Each portfolio has its own investment objective  and
policies  designed to meet  its specific goals. This  Prospectus pertains to the
Class A and Class B shares of the Technology Portfolio, the investment objective
of which is as follows:
 
   
    -The TECHNOLOGY PORTFOLIO seeks long-term capital appreciation by  investing
     primarily  in equity  securities of companies  that, in the  opinion of the
     Portfolio's  investment  adviser,  are  expected  to  benefit  from   their
     involvement in technology and technology-related industries.
    
 
    The  other portfolios of the Fund  are described in other prospectuses which
may be obtained from the Fund at the address and phone number noted on the cover
of this  Prospectus. The  investment objectives  of these  other portfolios  are
listed below.
 
    GLOBAL AND INTERNATIONAL EQUITY:
 
    -The   ACTIVE   COUNTRY   ALLOCATION  PORTFOLIO   seeks   long-term  capital
     appreciation by investing in accordance with country weightings  determined
     by  the  Adviser in  equity securities  of non-U.S.  issuers which,  in the
     aggregate, replicate broad country indices.
 
    -The  ASIAN  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation   by
     investing primarily in equity securities of Asian issuers.
 
    -The  CHINA GROWTH PORTFOLIO seeks to provide long-term capital appreciation
     by investing  primarily in  equity securities  of issuers  in The  People's
     Republic of China, Hong Kong and Taiwan.
 
    -The  EMERGING  MARKETS PORTFOLIO  seeks  long-term capital  appreciation by
     investing primarily in equity securities of emerging country issuers.
 
    -The EUROPEAN  EQUITY  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing primarily in equity securities of European issuers.
 
    -The  GLOBAL  EQUITY  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing primarily in equity securities  of issuers throughout the  world,
     including U.S. issuers.
 
    -The  GOLD  PORTFOLIO  seeks  long-term  capital  appreciation  by investing
     primarily in equity securities of  foreign and domestic issuers engaged  in
     gold-related activities.
 
    -The  INTERNATIONAL EQUITY PORTFOLIO seeks long-term capital appreciation by
     investing primarily in equity securities of non-U.S. issuers.
 
    -The INTERNATIONAL MAGNUM PORTFOLIO seeks long-term capital appreciation  by
     investing  primarily in equity securities  of non-U.S. issuers domiciled in
     EAFE countries.
 
    -The INTERNATIONAL SMALL CAP PORTFOLIO seeks long-term capital  appreciation
     by investing primarily in equity securities of non-U.S. issuers with equity
     market capitalizations of less than $1 billion.
 
                                       6
<PAGE>
    -The  JAPANESE  EQUITY  PORTFOLIO seeks  long-term  capital  appreciation by
     investing primarily in equity securities of Japanese issuers.
 
   
    -The LATIN  AMERICAN  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing  primarily in  equity securities  of Latin  American issuers and,
     from time to time, debt securities  issued or guaranteed by Latin  American
     governments or governmental entities.
    
 
    U.S. EQUITY:
 
    -The  AGGRESSIVE EQUITY  PORTFOLIO seeks  capital appreciation  by investing
     primarily in corporate equity and equity-linked securities.
 
    -The EMERGING  GROWTH  PORTFOLIO  seeks long-term  capital  appreciation  by
     investing  primarily  in  growth-oriented equity  securities  of  small- to
     medium-sized corporations.
 
    -The  EQUITY  GROWTH  PORTFOLIO  seeks  long-term  capital  appreciation  by
     investing   in  growth-oriented  equity  securities  of  medium  and  large
     capitalization companies.
 
    -The MICROCAP PORTFOLIO  seeks long-term capital  appreciation by  investing
     primarily in growth-oriented equity securities of small corporations.
 
    -The  SMALL CAP VALUE EQUITY PORTFOLIO  seeks high long-term total return by
     investing in  undervalued  equity  securities  of  small-  to  medium-sized
     companies.
 
    -The  U.S.  REAL ESTATE  PORTFOLIO seeks  to  provide above  average current
     income and long-term capital appreciation by investing primarily in  equity
     securities  of companies in  the U.S. real  estate industry, including real
     estate investment trusts.
 
    -The VALUE EQUITY PORTFOLIO seeks high  total return by investing in  equity
     securities  which the  Adviser believes to  be undervalued  relative to the
     stock market in general at the time of purchase.
 
    EQUITY AND FIXED INCOME:
 
    -The BALANCED PORTFOLIO seeks high total return while preserving capital  by
     investing  in  a combination  of  undervalued equity  securities  and fixed
     income securities.
 
    FIXED INCOME:
 
    -The EMERGING MARKETS DEBT  PORTFOLIO seeks high  total return by  investing
     primarily   in  debt  securities   of  government,  government-related  and
     corporate issuers located in emerging countries.
 
    -The FIXED INCOME PORTFOLIO seeks to produce a high total return  consistent
     with the preservation of capital by investing in a diversified portfolio of
     fixed income securities.
 
    -The  GLOBAL FIXED INCOME PORTFOLIO seeks to produce an attractive real rate
     of return while preserving capital by investing in fixed income  securities
     of issuers throughout the world, including U.S. issuers.
 
    -The  HIGH YIELD PORTFOLIO seeks to maximize  total return by investing in a
     diversified portfolio of high  yield fixed income  securities that offer  a
     yield  above  that  generally available  on  debt securities  in  the three
     highest rating categories of the recognized rating services.
 
    -The MORTGAGE-BACKED SECURITIES PORTFOLIO seeks  to produce as high a  level
     of  current income  as is  consistent with  the preservation  of capital by
     investing  primarily  in  a  variety  of  investment-grade  mortgage-backed
     securities.
 
                                       7
<PAGE>
    -The  MUNICIPAL  BOND PORTFOLIO  seeks to  produce a  high level  of current
     income consistent with preservation of principal by investing primarily  in
     municipal  obligations, the interest on which is exempt from federal income
     tax.
 
    MONEY MARKET:
 
    -The MONEY MARKET PORTFOLIO  seeks to maximize  current income and  preserve
     capital  while maintaining  high levels  of liquidity  through investing in
     high quality money market instruments with remaining maturities of one year
     or less.
 
    -The MUNICIPAL MONEY MARKET PORTFOLIO  seeks to maximize current  tax-exempt
     income  and  preserve capital  while maintaining  high levels  of liquidity
     through investing in high quality  money market instruments with  remaining
     maturities of one year or less which are exempt from federal income tax.
 
   THE  CHINA  GROWTH, MICROCAP  AND  MORTGAGE-BACKED SECURITIES  PORTFOLIOS ARE
   CURRENTLY NOT BEING OFFERED.
 
INVESTMENT MANAGEMENT
 
   
    Morgan Stanley Asset  Management Inc., a  wholly-owned subsidiary of  Morgan
Stanley  Group  Inc.,  which,  together  with  its  affiliated  asset management
companies, at March  31, 1997  had in  excess of  $118 billion  in assets  under
management  as  an  investment  manager  or  as  a  fiduciary  adviser,  acts as
investment adviser to the  Fund and each of  its portfolios. See "Management  of
the Fund -- Investment Adviser" and "Management of the Fund -- Administrator."
    
 
HOW TO INVEST
 
    Class  A shares of  the Portfolio are  offered directly to  investors at net
asset value with no  sales commission or  12b-1 charges. Class  B shares of  the
Portfolio  are offered at net  asset value with no  sales commission, but with a
12b-1 fee, which  is accrued daily  and paid  quarterly, equal to  0.25% of  the
Class B shares' average daily net assets on an annualized basis. Share purchases
may  be  made  by  sending  investments directly  to  the  Fund  or  through the
Distributor. The minimum initial investment, generally, is $250,000 for Class  A
shares  of the Portfolio  and $50,000 for  Class B shares  of the Portfolio. The
minimum  initial  investment  amount  is  reduced  for  certain  categories   of
investors.  For additional  information on  how to  purchase shares  and minimum
initial investments, see "Purchase of Shares."
 
HOW TO REDEEM
 
    Shares of the Portfolio may  be redeemed at any  time, without cost, at  the
net  asset value  per share  of shares of  the applicable  class next determined
after receipt of  the redemption request.  The redemption price  may be more  or
less  than the purchase  price. Certain redemptions  that cause the  value of an
account to remain for  a continuous 60-day period  below the minimum  investment
amount  for  Class A  shares or  for Class  B shares  may result  in involuntary
redemption or automatic conversion. For additional information on how to  redeem
shares  and involuntary  redemption or  conversion, see  "Purchase of  Shares --
Minimum Account Sizes and Involuntary  Redemption of Shares" and "Redemption  of
Shares."
 
                                       8
<PAGE>
RISK FACTORS
 
   
    The   investment  policies  of  the   Portfolio  entail  certain  risks  and
considerations of  which  an  investor  should  be  aware.  In  particular,  the
Portfolio's   concentration  in  technology  securities  presents  special  risk
considerations. For  example,  the  value  of  the  Portfolio's  shares  may  be
susceptible  to factors  affecting technology  and technology-related industries
and to greater  risk and market  fluctuation than an  investment in a  portfolio
that  invests in a broader range  of portfolio securities. In certain instances,
technology companies  may experience  dramatic price  movements precipitated  by
investors'   excessive  optimism  or  pessimism  with  little  or  no  basis  in
fundamental economic  conditions. Technology  and technology-related  industries
may  produce or use  products or services  that prove commercially unsuccessful,
become obsolete  quickly  or  become  adversely  affected  by  U.S.  or  foreign
government  regulation. Additionally, these companies may be subject to risks of
developing technologies,  competitive  pressure and  other  factors and  may  be
dependent  upon consumer and business acceptance as new technologies evolve. The
Portfolio will invest  in securities  of foreign issuers,  including issuers  in
emerging  countries, which are subject to certain risks not typically associated
with domestic securities, including (1)  restrictions on foreign investment  and
on   repatriation  of  capital  invested  in  foreign  countries,  (2)  currency
fluctuations, (3) the cost of converting foreign currency into U.S. dollars, (4)
potential price  volatility and  lesser liquidity  of shares  traded on  foreign
country  securities  markets or  lack  of a  secondary  trading market  for such
securities  and  (5)  political  and  economic  risks,  including  the  risk  of
nationalization  of expropriation  of assets and  the risk of  war. In addition,
accounting,  auditing,  financial  and  other  reporting  standards  in  foreign
countries  are not  equivalent to  U.S. standards  and therefore,  disclosure of
certain material  information  may not  be  made  and less  information  may  be
available to investors investing in foreign countries than in the United States.
There  is also generally less governmental regulation of the securities industry
in foreign countries than the United States. Moreover, it may be more  difficult
to  obtain a judgment  in a court  outside the United  States. The Portfolio may
invest in  certain  derivatives,  including  options,  futures  and  options  on
futures.  These investments entail certain  costs and risks, including imperfect
correlation between the value of securities held by the Portfolio and the  value
of  the particular derivative instrument, and  the risk that the Portfolio could
not close out a derivatives  position when it would  be most advantageous to  do
so. In addition, the Portfolio may engage in short sales, purchase securities on
a  when-issued or delayed delivery basis  and invest in foreign currency forward
contracts to hedge currency risk  associated with investment in non-U.S.  dollar
denominated  securities. Each  of these investment  strategies involves specific
risks  which  are  described  under  "Investment  Objective  and  Policies"  and
"Additional Investment Information."
    
 
                                       9
<PAGE>
                       INVESTMENT OBJECTIVE AND POLICIES
 
   
    The  investment objective of  the Portfolio is  to provide long-term capital
appreciation. The  production  of  any  current income  is  incidental  to  this
objective.  The Portfolio seeks to achieve  its objective by investing primarily
in equity  securities of  companies that,  in the  opinion of  the Adviser,  are
expected  to benefit from their investment  in technology and technology related
industries. At least 65% of the total  assets of the Portfolio will be  invested
in   the  equity  securities   of  such  "technology"   companies  under  normal
circumstances. The Portfolio expects to invest in companies in a broad range  of
technology  and  technology related  industries including,  but not  limited to:
computers,  software  and   peripheral  products;  electronics;   communications
equipment  and  services; entertainment;  multimedia; and  information services.
With respect to the  Portfolio, equity securities  include common and  preferred
stocks,  convertible securities, rights and  warrants to purchase common stocks,
and any similar equity interests, such  as trust or partnership interests.  Such
equity  securities may or may not pay  dividends or distributions and may or may
not carry voting rights. The  Portfolio's investment objective is a  fundamental
policy  which  may not  be changed  without the  approval of  a majority  of the
Portfolio's outstanding  voting  securities.  There is  no  assurance  that  the
Portfolio  will attain its objectives. Other investment policies described below
are not fundamental policies and may be changed without shareholder approval. In
addition to the investments  and strategies described  below, the Portfolio  may
invest  in  certain  securities  and obligations  as  set  forth  in "Additional
Investment Information" below and as described under "Investment Objectives  and
Policies" in the Statement of Additional Information.
    
 
    The Portfolio may invest up to 35% of its total assets in the equity or debt
securities   of  foreign  issuers   to  permit  the   Portfolio  to  participate
sufficiently in  the  global technology  market.  The Portfolio  may  invest  in
Depositary  Receipts, including American  Depositary Receipts, Global Depositary
Receipts or similar securities that  are convertible into securities of  foreign
issuers  and  that  evidence  ownership  of  the  underlying  foreign  security.
Depositary Receipts  may  not  be  denominated  in  the  same  currency  as  the
underlying  securities  into which  they  may be  converted.  In the  event that
Depositary Receipts are not available  for a particular security, the  Portfolio
may  invest directly  in that  security, which  may or  may not  be listed  on a
foreign exchange.  The securities  in  which the  Portfolio  may invest  may  be
denominated  in  any currency.  The Portfolio  may  enter into  foreign currency
forward contracts  in  connection  with the  settlement  of  foreign  securities
transactions  or to  hedge the underlying  currency exposure  related to foreign
investments. The Portfolio will not enter into these commitments for speculative
purposes.  Investors  should  recognize  that  investing  in  foreign  companies
involves  certain special considerations that  are not typically associated with
investing in U.S. companies.
 
    The Portfolio may invest  in the equity securities  of both large and  small
companies. While the Adviser believes that smaller companies can provide greater
growth   potential  than  larger,  more  established  firms,  investing  in  the
securities of smaller companies also  involves greater risk and portfolio  price
volatility.  Among the reasons  for this greater price  volatility are the lower
degree of market liquidity (the securities of companies with small stock  market
capitalizations may trade less frequently and in limited volume) and the greater
sensitivity of small companies to changing economic conditions.
 
                                       10
<PAGE>
                       ADDITIONAL INVESTMENT INFORMATION
 
    CONVERTIBLE   SECURITIES,  WARRANTS  AND   EQUITY-LINKED  SECURITIES.    The
Portfolio may invest  in securities  such as  convertible securities,  preferred
stock, warrants or other securities exchangeable under certain circumstances for
shares  of common stock. Warrants are  instruments giving holders the right, but
not the  obligation, to  buy shares  of  a company  at a  given price  during  a
specified period.
 
    The  Portfolio may invest in  equity-linked securities, which are securities
that are convertible into,  or the value  of which is based  upon the value  of,
equity  securities upon certain terms and  conditions. The amount received by an
investor at maturity of such securities is  not fixed but is based on the  price
of the underlying common stock. It is impossible to predict whether the price of
the  underlying common stock will rise or fall. Trading prices of the underlying
common stock will be influenced by the issuer's operational results, by complex,
interrelated political,  economic, financial,  or  other factors  affecting  the
capital  markets, the  stock exchanges on  which the underlying  common stock is
traded and the market segment of which the issuer is a part. In addition, it  is
not possible to predict how equity-linked securities will trade in the secondary
market, which is fairly developed and liquid. The market for such securities may
be  shallow,  however,  and  high  volume  trades  may  be  possible  only  with
discounting. In addition to the foregoing  risks, the return on such  securities
depends  on the creditworthiness of  the issuer of the  securities, which may be
the issuer of  the underlying  securities or a  third party  investment bank  or
other  lender. The creditworthiness of such  third party issuer of equity-linked
securities may, and often does, exceed the creditworthiness of the issuer of the
underlying securities.  The advantage  of  using equity-linked  securities  over
traditional  equity and debt securities is  that the former are income producing
vehicles that  may provide  a higher  income  than the  dividend income  on  the
underlying  equity securities while  allowing some participation  in the capital
appreciation of the  underlying equity  securities. Another  advantage of  using
equity-linked securities is that they may be used for hedging to reduce the risk
of investing in the generally more volatile underlying equity securities.
 
   
    DEPOSITARY  RECEIPTS.   The  Portfolio  may invest  in  Depositary Receipts,
including American  Depositary  Receipts ("ADRs"),  Global  Depositary  Receipts
("GDRs"),  European Depositary  Receipts ("EDRs") and  other Depositary Receipts
(which, together with ADRs, GDRs and EDRs, are hereinafter collectively referred
to as "Depositary Receipts"), to the extent that such Depositary Receipts are or
become available.  ADRs are  securities  typically issued  by a  U.S.  financial
institution (a "depositary"), that evidence ownership interests in a security or
pool  of securities  issued by  a foreign  issuer (the  "underlying issuer") and
deposited with the depositary. ADRs  include American Depositary Shares and  New
York  Shares  and  may  be  "sponsored"  or  "unsponsored."  Sponsored  ADRs are
established  jointly  by  a  depositary  and  the  underlying  issuer,   whereas
unsponsored ADRs may be established by a depositary without participation by the
underlying  issuer.  The  issuers  of  the stock  of  unsponsored  ADRs  are not
obligated to disclose material information  in the United States and  therefore,
there  may not be a correlation between such information and the market value of
the ADR. GDRs, EDRs and other types of Depositary Receipts are typically  issued
by  foreign depositaries, although they may also be issued by U.S. depositaries,
and evidence ownership interests in a  security or pool of securities issued  by
either  a  foreign  or a  U.S.  corporation. Generally,  Depositary  Receipts in
registered form  are  designed  for  use  in  the  U.S.  securities  market  and
Depositary  Receipts in bearer  form are designed for  use in securities markets
outside the United States. The Portfolio may invest in sponsored and unsponsored
Depositary Receipts. For  purposes of the  Portfolio's investment policies,  the
Portfolio's  investments in Depositary Receipts will be deemed to be investments
in the underlying securities.
    
 
                                       11
<PAGE>
   
    FOREIGN CURRENCY FORWARD CONTRACTS.   The Portfolio  may enter into  foreign
currency  forward contracts ("forward contracts")  that provide for the purchase
or sale of an amount of a specified currency at a future date. The Portfolio may
use such contracts to  protect against a decline  in a foreign currency  against
the  U.S. dollar between the  trade date and settlement  date when the Portfolio
purchases or sells securities,  lock in the U.S.  dollar value of dividends  and
interest  on securities held by the Portfolio, and generally to protect the U.S.
dollar  value  of  securities  held  by  the  Portfolio  against  exchange  rate
fluctuation.  While forward contracts  may limit losses as  a result of exchange
rate fluctuations, they will also limit any gains that might otherwise have been
realized. The Portfolio's  Custodian may  be required  to place  cash or  liquid
securities  in  a segregated  account in  an amount  equal to  the value  of the
Portfolio's total assets committed to the consummation of forward contracts.  If
the  value  of  the  securities  placed  in  the  segregated  account  declines,
additional cash or securities will be placed in the account on a daily basis  so
that  the value  of the  account will  be at  least equal  to the  amount of the
Portfolio's commitments with respect to such contracts.
    
 
    FOREIGN CURRENCY HEDGING TRANSACTIONS.   In order  to hedge against  foreign
currency  exchange rate  risks, the  Portfolio may  enter into  foreign currency
futures contracts  and options  on such  contracts. Purposes  for which  futures
contracts may be used include protecting against a decline in a foreign currency
against  the U.S.  dollar between  the trade date  and settlement  date when the
Portfolio purchases or  sells securities, locking  in the U.S.  dollar value  of
dividends  declared on securities held by the Portfolio and generally protecting
the U.S. dollar value of securities held by the Portfolio against exchange  rate
fluctuations. The Portfolio may also enter into futures contracts and options on
futures contracts to remain fully invested, to reduce transaction costs and as a
hedge  against fluctuations in  the price of  a security it  holds or intends to
acquire, but not for speculation or for achieving leverage.
 
    A foreign  currency futures  contract  is a  standardized contract  for  the
future  delivery of a specified amount of a foreign currency at a future date at
a price set  at the  time of the  contract. Foreign  currency futures  contracts
traded  in the  U.S. are  traded on  regulated exchanges.  Parties to  a futures
contract must  make  initial "margin"  deposits  to secure  performance  of  the
contract,  which generally range from 2% to 5% of the contract price. There also
are requirements to make "variation" margin deposits as the value of the futures
contract fluctuates. The Portfolio may  not enter into foreign currency  futures
contracts  if the aggregate amount of initial margin deposits on the Portfolio's
futures positions would exceed 5% of the value of the Portfolio's total  assets.
The  Portfolio also will  be required to  segregate assets to  cover its futures
contracts obligations.
 
    At the maturity of  a futures contract, the  Portfolio may either accept  or
make  delivery of the currency specified in  the contract or, prior to maturity,
enter into a closing purchase transaction  involving the purchase or sale of  an
offsetting  contract.  Closing  purchase transactions  with  respect  to futures
contracts are effected  on an  exchange. The Portfolio  will only  enter into  a
futures  contract if it is expected that there  will be a liquid market in which
to close out such contract.  There can, however, be  no assurance that a  liquid
market will exist in which to close a forward or futures contract, in which case
the Portfolio may suffer a loss.
 
    The  Portfolio  may  purchase and  write  call  and put  options  on futures
contracts that are traded on any international exchange, traded over-the-counter
or which  are synthetic  options or  futures  or equity  swaps, may  enter  into
closing  transactions  with respect  to such  options  to terminate  an existing
position. An option  on a  futures contract gives  the purchaser  the right  (in
return  for the premium paid) to assume a position in a futures contract (a long
position if the option is a call and a short position if the option is a put) at
a specified  exercise price  at any  time during  the term  of the  option.  The
Portfolio will purchase and write options on futures
 
                                       12
<PAGE>
contracts  for identical purposes to those set forth above for the purchase of a
futures contract (purchase of  a call option  or sale of a  put option) and  the
sale  of a futures contract (purchase of a put option or sale of a call option),
or to close out a long or short position in the future contracts. While  futures
contracts  may  limit losses  to  the Portfolio  as  a result  of  exchange rate
fluctuation, they  will  also limit  any  gains  that may  otherwise  have  been
realized.  The primary risks associated  with the use of  futures and options on
futures are (i) imperfect correlation between the change in market value of  the
securities  held by the Portfolio and the prices of futures and options relating
to the securities purchased or sold by the Portfolio; and (ii) possible lack  of
a  liquid secondary market for an option or a futures contract and the resulting
inability to close a futures position which could have an adverse impact on  the
Portfolio's ability to hedge. In the opinion of the Board of Directors, the risk
that  the Portfolio will  be unable to  close out a  futures position or options
contract will be minimized by only entering into futures contracts or options on
futures contracts for which there appears to be a liquid secondary market.
 
    FOREIGN INVESTMENT.   The  Portfolio  may invest  in securities  of  foreign
issuers.  Investment in obligations of foreign issuers, especially in securities
of issuers in emerging countries,  involves somewhat different investment  risks
than those affecting obligations of U.S. issuers. As used in this Prospectus, an
emerging  country is any country that  the International Bank for Reconstruction
and Development (more commonly known as the World Bank) has determined to have a
low  or  middle  income  economy.  There  may  be  limited  publicly   available
information  with  respect  to  foreign issuers,  and  foreign  issuers  are not
generally subject to  uniform accounting, auditing  and financial standards  and
requirements comparable to those applicable to U.S. companies. There may also be
less  government  supervision and  regulation  of foreign  securities exchanges,
brokers and listed companies than in the United States. Many foreign  securities
markets  have substantially less volume than U.S. national securities exchanges,
and securities of some  foreign issuers are less  liquid and more volatile  than
securities  of  comparable  domestic issuers.  Brokerage  commissions  and other
transaction costs on foreign securities  exchanges are generally higher than  in
the United States. Dividends and interest paid by foreign issuers may be subject
to  withholding and other  foreign taxes, which  may decrease the  net return on
foreign investments as compared to dividends and interest paid to the  Portfolio
by domestic companies. It is not expected that the Portfolio or its shareholders
would  be able to claim a credit for  U.S. tax purposes with respect to any such
foreign  taxes.  Additional   risks  include  future   political  and   economic
developments, the possibility that a foreign jurisdiction might impose or change
withholding taxes on income payable with respect to foreign securities, possible
seizure,  nationalization  or expropriation  of  the foreign  issuer  or foreign
deposits and the possible adoption of foreign governmental restrictions such  as
exchange   controls.  Emerging   countries  may   have  less   stable  political
environments than more developed  countries. Also, it may  be more difficult  to
obtain judgment in a court outside the United States.
 
    Such investments in securities of foreign issuers are frequently denominated
in  foreign currencies, and since the  Portfolio may temporarily hold uninvested
reserves in bank deposits  in foreign currencies, the  value of the  Portfolio's
assets  as measured in U.S. dollars may  be affected favorably or unfavorably by
changes in currency rates and in exchange control regulations, and the Portfolio
may incur costs in connection with conversions between various currencies.
 
   
    FUTURES CONTRACTS  AND OPTIONS  ON  FUTURES CONTRACTS.   The  Portfolio  may
purchase  and sell futures contracts and options on futures contracts, including
but not limited to financial futures, securities index futures, foreign currency
exchange futures, and interest rate futures contracts. Futures contracts provide
for the sale by one party and purchase by another party of a specified amount of
a specific security, instrument or basket
    
 
                                       13
<PAGE>
   
thereof, at a  specific future date  and at a  specified price. An  option on  a
futures  contract is a legal contract that gives  the holder the right to buy or
sell a specified amount  of futures contracts at  a fixed or determinable  price
upon the exercise of the option.
    
 
   
    The  Portfolio may  sell securities  index futures  contracts and/or options
thereon in anticipation of or during a  market decline to attempt to offset  the
decrease in market value of investments in its portfolio, or purchase securities
index  futures in order to gain market exposure. Subject to applicable laws, the
Portfolio may engage in transactions in securities index futures contracts  (and
options  thereon)  which  are  traded  on  a  recognized  securities  or futures
exchange, or  may purchase  or  sell such  instruments in  the  over-the-counter
market. There currently are limited securities index futures and options on such
futures  in many countries,  particularly emerging countries.  The nature of the
strategies adopted by the Adviser, and the extent to which those strategies  are
used, may depend on the development of such markets.
    
 
   
    The Portfolio may engage in transactions involving foreign currency exchange
futures  contracts. Such contracts  involve an obligation to  purchase or sell a
specific currency  at a  specified future  date and  at a  specified price.  The
Portfolio may engage in such transactions to hedge their respective holdings and
commitments  against changes in  the level of  future currency rates  or to gain
exposure to a particular currency.
    
 
   
    The  Portfolio  may  engage  in   transactions  in  interest  rate   futures
transactions.  Interest rate futures contracts involve an obligation to purchase
or sell a specific  debt security, instrument or  basket thereof at a  specified
future  date at  a specified price.  The value  of the contract  rises and falls
inversely with  changes in  interest rates.  The Portfolio  may engage  in  such
transactions  to hedge their holdings of debt instruments against future changes
in interest rates.
    
 
   
    Financial futures are futures  contracts relating to financial  instruments,
such  as  U.S. Government  securities, foreign  currencies, and  certificates of
deposit. Such contracts  involve an obligation  to purchase or  sell a  specific
security, instrument or basket thereof at a specified future date at a specified
price.  Like interest  rate futures  contracts, the  value of  financial futures
contracts rises  and  falls  inversely  with  changes  in  interest  rates.  The
Portfolio  may engage in financial futures contracts for hedging and non-hedging
purposes.
    
 
   
    Under rules  adopted  by  the  Commodity  Futures  Trading  Commission,  the
Portfolio  may enter into futures contracts and options thereon for both hedging
and non-hedging purposes,  provided that  not more  than 5%  of the  Portfolio's
total  assets at the time of entering the transaction are required as margin and
option  premiums  to  secure  obligations  under  such  contracts  relating   to
activities  that do not  constitute "bona fide" hedging.  The Portfolio will not
enter into futures contracts to the  extent that its outstanding obligations  to
purchase  securities under such  contracts, in combination  with its outstanding
obligations with respect to options transactions (including options to  purchase
securities or instruments) would exceed 20% of its total assets.
    
 
   
    Gains  and losses  on futures  contracts and  options thereon  depend on the
Adviser's ability  to  predict correctly  the  direction of  securities  prices,
interest  rates and other economic factors.  Other risks associated with the use
of futures  and options  are (i)  imperfect correlation  between the  change  in
market  value of investments held by the Portfolio and the prices of futures and
options relating to  investments purchased or  sold by the  Portfolio, and  (ii)
possible  lack  of a  liquid secondary  market  for a  futures contract  and the
resulting inability to  close a futures  position. The risk  that the  Portfolio
will  be unable  to close  out a  futures position  or options  contract will be
minimized by only entering  into futures contracts  or options transactions  for
which there
    
 
                                       14
<PAGE>
   
appears to be a liquid exchange or secondary market. The risk of loss in trading
on  futures contracts in some strategies can be substantial, due both to the low
margin deposits required and the extremely  high degree of leverage involved  in
futures pricing.
    
 
    INVESTMENT  FUNDS.   Some foreign countries  have laws  and regulations that
currently  preclude  direct  foreign  investment  in  the  securities  of  their
companies.  However, indirect foreign investment  in the securities of companies
listed and traded  on the  stock exchanges in  these countries  is permitted  by
certain   foreign  countries  through  investment   companies  which  have  been
specifically authorized. The Portfolio may invest in these investment  companies
subject to the provisions of the Investment Company Act of 1940, as amended (the
"1940  Act"),  and  other applicable  laws.  If  the Portfolio  invests  in such
investment companies,  the Portfolio's  shareholders will  bear not  only  their
proportionate  share  of  the  expenses of  the  Portfolio  (including operating
expenses and the  fees of the  Adviser), but also  will indirectly bear  similar
expenses of the underlying investment companies.
 
    Certain  of the investment companies referred  to in the preceding paragraph
are advised by the Adviser. The Portfolio may, to the extent permitted under the
1940 Act and other applicable law, invest in these investment companies. If  the
Portfolio  does elect to  make an investment  in such an  investment company, it
will only purchase the  securities of such investment  company in the  secondary
market.
 
    LOANS  OF PORTFOLIO  SECURITIES.  The  Portfolio may lend  its securities to
brokers, dealers, domestic and foreign banks or other financial institutions for
the purpose of increasing its net investment income. These loans must be secured
continuously by cash or equivalent collateral or by a letter of credit at  least
equal  to the  market value  of the securities  loaned plus  accrued interest or
income. There may be risks of delay  in recovery of the securities or even  loss
of  rights  in  the  collateral  should  the  borrower  of  the  securities fail
financially. The  Portfolio will  not enter  into securities  loan  transactions
exceeding,  in the  aggregate, 33  1/3% of the  market value  of the Portfolio's
total assets.
 
    LOWER RATED DEBT SECURITIES.  The Portfolio may invest up to 15% of its  net
assets  in lower rated or unrated debt securities, commonly referred to as "junk
bonds." In addition, the emerging country debt securities in which the Portfolio
may invest will not be required to meet a minimum rating standard and may not be
rated. Fixed income securities are subject to the risk of an issuer's  inability
to meet principal and interest payments on the obligations (credit risk) and may
also  be  subject to  price  volatility due  to  such factors  as  interest rate
sensitivity, market perception of the creditworthiness of the issuer and general
market liquidity  (market risk).  Lower  rated or  unrated securities  are  more
likely  to react to developments affecting market  and credit risk than are more
highly rated securities, which react primarily to movements in the general level
of interest rates.  The market values  of fixed-income securities  tend to  vary
inversely  with the level of  interest rates. Yields and  market values of lower
rated and unrated debt securities will fluctuate over time, reflecting not  only
changing  interest rates but  the market's perception of  credit quality and the
outlook  for   economic  growth.   When  economic   conditions  appear   to   be
deteriorating,  medium to  lower rated  securities may  decline in  value due to
heightened concern over credit quality, regardless of prevailing interest rates.
Fluctuations in the value  of the Portfolio's investments  will be reflected  in
the  Portfolio's net  asset value per  share. The Adviser  considers both credit
risk and market risk in making investment decisions for the Portfolio. Investors
should carefully consider  the relative risks  of investing in  lower rated  and
unrated  debt securities and  understand that such  securities are not generally
meant for short-term investing.
 
                                       15
<PAGE>
    The market for lower rated and unrated debt securities is relatively new and
its recent growth paralleled a long period of economic expansion and an increase
in  merger,  acquisition  and   leveraged  buyout  activity.  Adverse   economic
developments  may disrupt the market for  U.S. corporate lower rated and unrated
debt securities and for emerging  country debt securities. Such disruptions  may
severely  affect the ability of issuers, especially highly leveraged issuers, to
service their debt obligations or to  repay their obligations upon maturity.  In
addition,  the secondary  market for  lower rated  and unrated  debt securities,
which is concentrated in relatively few market  makers, may not be as liquid  as
the  secondary market for more highly rated securities. As a result, the Adviser
could find it more difficult to sell these securities or may be able to sell the
securities only at prices lower than  if such securities were widely traded.  In
addition  there may  be limited trading  markets for debt  securities of issuers
located in emerging countries. Prices realized upon the sale of such lower rated
or unrated securities, under  these circumstances, may be  less than the  prices
used in calculating the Portfolio's net asset value.
 
    Prices  for  lower rated  and  unrated debt  securities  may be  affected by
legislative and regulatory developments. These  laws could adversely affect  the
Portfolio's  net asset value and investment  practices, the secondary market for
lower rated and unrated debt securities,  the financial condition of issuers  of
such  securities  and the  value  of outstanding  lower  rated and  unrated debt
securities. For example, U.S. federal  legislation requiring the divestiture  by
federally  insured savings and  loan associations of  their investments in lower
rated and unrated debt securities and limiting the deductibility of interest  by
certain  corporate issuers of lower rated  and unrated debt securities adversely
affected the market in recent years.
 
   
    Lower rated or unrated debt obligations also present risks based on  payment
expectations.  If an issuer calls the  obligations for redemption, the Portfolio
may have to replace the security with a lower yielding security, resulting in  a
decreased  return  for investors.  If the  Portfolio experiences  unexpected net
redemptions, it may be forced to sell its higher rated securities, resulting  in
a  decline in the overall credit quality of the Portfolio's investment portfolio
and increasing the exposure  of the Portfolio  to the risks  of lower rated  and
unrated debt securities.
    
 
   
    MONEY  MARKET INSTRUMENTS.   The Portfolio  is permitted to  invest in money
market  instruments,  although  the  Portfolio  intends  to  stay  invested   in
securities  satisfying its primary investment objective to the extent practical.
The Portfolio  may make  money market  investments pending  other investment  or
settlement  for  liquidity,  or  in adverse  market  conditions.  See "Temporary
Investments." The money market investments  permitted for the Portfolio  include
obligations  of  the U.S.  Government  and its  agencies  and instrumentalities;
obligations of foreign sovereignties;  other debt securities; commercial  paper;
bank  obligations; certificates of deposit (including Eurodollar certificates of
deposit); and repurchase agreements.
    
 
    NON-PUBLICLY  TRADED   SECURITIES,   PRIVATE   PLACEMENTS   AND   RESTRICTED
SECURITIES.  The Portfolio may invest in securities that are neither listed on a
stock  exchange nor traded over the counter. Such unlisted equity securities may
involve a  higher degree  of business  and  financial risk  that can  result  in
substantial  losses. As a result  of the absence of  a public trading market for
these securities,  they may  be  less liquid  than publicly  traded  securities.
Although  these securities may  be resold in  privately negotiated transactions,
the prices realized from these sales could be less than those originally paid by
the Portfolio  or less  than  what may  be considered  the  fair value  of  such
securities.  Further, companies whose securities are not publicly traded may not
be subject to the  disclosure and other  investor protection requirements  which
might be applicable if their securities were publicly traded. If such securities
are  required  to  be  registered  under the  securities  laws  of  one  or more
jurisdictions before being  resold, the Portfolio  may be required  to bear  the
expenses of registration.
 
                                       16
<PAGE>
   
    As  a general matter, the Portfolio may not  invest more than 15% of its net
assets in  illiquid  securities, including  securities  for which  there  is  no
readily available secondary market. Securities that are not registered under the
Securities  Act  of  1933, as  amended,  but that  can  be offered  and  sold to
qualified institutional  buyers  under Rule  144A  under that  Act  ("Rule  144A
Securities")  will not be  included within the foregoing  15% restriction if the
securities are  determined to  be liquid.  The Board  of Directors  has  adopted
guidelines and delegated to the Adviser, subject to the supervision of the Board
of  Directors, the daily function of determining and monitoring the liquidity of
Rule 144A  securities. Rule  144A securities  may become  illiquid if  qualified
institutional  buyers  are  not  interested  in  acquiring  the  securities.  In
addition, the Portfolio may invest up to  10% of its total assets in  restricted
securities,  and up to 25% of its total assets in restricted securities that are
Rule 144A securities.
    
 
   
    OPTIONS TRANSACTIONS.  The Portfolio may seek to increase its return or  may
hedge  its portfolio  investments through  options transactions  with respect to
securities, instruments, indices or baskets  thereof in which the Portfolio  may
invest,  as well as  with respect to  foreign currency. Purchasing  a put option
gives the Portfolio the right to  sell a specified security, currency or  basket
of  securities or currencies at  the exercise price until  the expiration of the
option. Purchasing a  call option gives  the Portfolio the  right to purchase  a
specified  security,  currency  or basket  of  securities or  currencies  at the
exercise price  until  the expiration  of  the  option. The  Portfolio  may  not
purchase  call and  put options to  the extent  that the value  of its aggregate
investment in options exceeds 5% of its total assets.
    
 
   
    The  Portfolio  also  may  write  (i.e.,  sell)  put  and  call  options  on
investments  held in its portfolio, as well as with respect to foreign currency.
A Portfolio that has written an  option receives a premium, which increases  the
Portfolio's  return on  the underlying security  or instrument in  the event the
option expires unexercised or is closed out  at a profit. However, by writing  a
call option, the Portfolio will limit its opportunity to profit from an increase
in  the market value of the underlying security or instrument above the exercise
price of the option for as long  as the Portfolio's obligation as writer of  the
option  continues. The  Portfolio may only  write options that  are "covered." A
covered call option  means that so  long as  the Portfolio is  obligated as  the
writer  of the  option, it  will own (i)  the underlying  security or instrument
subject  to  the  option  or  (ii)  securities  or  instruments  convertible  or
exchangeable  without  the payment  of any  consideration  into the  security or
instrument subject to the option.
    
 
   
    By writing (or selling) a put option, the Portfolio incurs an obligation  to
buy  the security or instrument underlying the  option from the purchaser of the
put at the option's exercise price at any time during the option period, at  the
purchaser's election. Options written by the Portfolio may be exercisable by the
purchaser  only on a  specific date. A  Portfolio that has  written a put option
will earmark  or segregate  sufficient liquid  assets to  cover its  obligations
under the option.
    
 
   
    The  Portfolio may  engage in  transactions in  options which  are traded on
recognized exchanges or  over-the-counter. There currently  are limited  options
markets  in  many  countries,  particularly  emerging  countries  such  as Latin
American countries, and the nature of the strategies adopted by the Adviser  and
the  extent to which those strategies are used will depend on the development of
such option markets. The  primary risks associated with  the use of options  are
(i)  imperfect correlation  between the  change in  market value  of investments
held, purchased or sold by the Portfolio  and the prices of options relating  to
such  investments; and (ii)  possible lack of  a liquid secondary  market for an
option.
    
 
                                       17
<PAGE>
    REPURCHASE AGREEMENTS.  The Portfolio  may enter into repurchase  agreements
with  brokers, dealers or  banks that meet the  credit guidelines established by
the Fund's Board of Directors. In  a repurchase agreement, the Portfolio buys  a
security  from a seller  that has agreed  to repurchase it  at a mutually agreed
upon date and price, reflecting the interest rate effective for the term of  the
agreement.  The term of these  agreements is usually from  overnight to one week
and never  exceeds one  year. Repurchase  agreements may  be viewed  as a  fully
collateralized  loan  of money  by the  Portfolio to  the seller.  The Portfolio
always receives securities with  a market value at  least equal to the  purchase
price  (including accrued interest) as collateral,  and this value is maintained
during the term  of the  agreement. If the  seller defaults  and the  collateral
value  declines, the Portfolio might incur a loss. If bankruptcy proceedings are
commenced with  respect to  the  seller, the  Portfolio's realization  upon  the
collateral  may  be  delayed  or  limited.  The  Portfolio  may  not  enter into
repurchase agreements with  more than seven  days to maturity  if, as a  result,
more  than 15% of the market value of the Portfolio's net assets are invested in
these agreements  and other  investments  for which  market quotations  are  not
readily available or which are otherwise illiquid.
 
    SMALL  AND  MEDIUM-SIZED  COMPANIES.   Because  the Portfolio  may  invest a
substantial portion  of its  assets in  small-to medium-sized  companies,  which
companies  are more  vulnerable to  financial and  other risks  than larger more
established companies, investments in the Portfolio may involve a higher  degree
of risk and price volatility than the general equity markets.
 
    SHORT  SALES.   The Portfolio  may from time  to time  sell securities short
consistent with applicable legal requirements. A short sale is a transaction  in
which  the Portfolio sells securities it owns or  has the right to acquire at no
added cost (i.e.,  "against the  box") or  does not  own (but  has borrowed)  in
anticipation  of a decline in the market price of the securities. To deliver the
securities to the buyer, the Portfolio  arranges through a broker to borrow  the
securities  and, in  so doing,  the Portfolio  becomes obligated  to replace the
securities borrowed at their market price  at the time of replacement. When  the
Portfolio  makes a short  sale of borrowed securities,  the proceeds it receives
from the sale will be  held on behalf of a  broker until the Portfolio  replaces
the  borrowed securities. The Portfolio may have  to pay a premium to borrow the
securities and must  pay any  dividends or  interest payable  on the  securities
until they are replaced.
 
   
    The  Portfolio's obligation to replace the securities borrowed in connection
with a short sale will be secured  by collateral deposited with the broker  that
consists  of cash or other liquid securities.  In addition, if the short sale is
not "against the box", the Portfolio will place in a segregated account with the
Custodian an amount of cash or other liquid securities equal to the  difference,
if  any, between (1)  the market value of  the securities sold  at the time they
were sold  short  and (2)  any  cash or  other  liquid securities  deposited  as
collateral with the broker in connection with the short sale. Short sales by the
Portfolio involve certain risks and special considerations. Possible losses from
short  sales differ  from losses  that could  be incurred  from a  purchase of a
security, because losses from short sales may be unlimited, whereas losses  from
purchases can equal only the total amount invested.
    
 
   
    TEMPORARY  INVESTMENTS.  For temporary  defensive purposes, when the Adviser
determines that market conditions warrant, each Portfolio may invest up to  100%
of  its assets in dollar and non-dollar denominated money market instruments and
short- and medium-term debt securities that  the Adviser believes to be of  high
quality,  or hold cash.  The short- and  medium-term debt securities  in which a
Portfolio may invest consist of (a)  obligations of the U.S. or foreign  country
governments,  their respective agencies or  instrumentalities; (b) bank deposits
and bank  obligations  (including certificates  of  deposit, time  deposits  and
bankers' acceptances)
    
 
                                       18
<PAGE>
of  U.S. or foreign country banks denominated in any currency; (c) floating rate
securities  and  other  instruments  denominated  in  any  currency  issued   by
international development agencies; (d) finance company and corporate commercial
paper  and  other  short-term corporate  debt  obligations of  U.S.  and foreign
country corporations meeting the Portfolio's  credit quality standards; and  (e)
repurchase  agreements  with  banks  and  broker-dealers  with  respect  to such
securities.
 
    WHEN-ISSUED AND DELAYED  DELIVERY SECURITIES.   The  Portfolio may  purchase
securities  on a  when-issued or delayed  delivery basis.  In such transactions,
instruments are bought with payment and  delivery taking place in the future  in
order  to secure what is considered to be  an advantageous yield or price at the
time of the transaction. Delivery of  and payment for these securities may  take
as  long as a month or  more after the date of  the purchase commitment but will
take place  no more  than 120  days after  the trade  date. The  Portfolio  will
maintain  with the custodian  a separate account with  a segregated portfolio of
high-grade debt securities or equity securities or cash or liquid securities  in
an  amount at least equal  to these commitments. The  payment obligation and the
interest rates that will be  received are each fixed  at the time the  Portfolio
enters  into  the commitment  and  no interest  accrues  to the  Portfolio until
settlement. Thus, it is possible that the market value at the time of settlement
could be higher or lower  than the purchase price  if, among other factors,  the
general  level of  interest rates  has changed.  It is  a current  policy of the
Portfolio not to enter into  when-issued commitments exceeding in the  aggregate
15%  of the market value of the Portfolio's total assets less liabilities, other
than the obligations created by these commitments.
 
                             INVESTMENT LIMITATIONS
 
    The Portfolio is a non-diversified portfolio under the 1940 Act, which means
that the Portfolio  is not  limited by  the 1940 Act  in the  proportion of  its
assets  that may be  invested in the  obligations of a  single issuer. Thus, the
Portfolio may invest a greater proportion of  its assets in the securities of  a
small  number of issuers  and as a result  will be subject  to greater risk with
respect to its portfolio  securities. However, the  Portfolio intends to  comply
with  diversification requirements imposed by the Internal Revenue Code of 1986,
as amended (the "Code"),  for qualification as  a regulated investment  company.
See "Investment Limitations" in the Statement of Additional Information.
 
    The  Portfolio also operates under  certain investment restrictions that are
deemed fundamental limitations and may be changed only with the approval of  the
holders  of a majority  of the Portfolio's outstanding  shares and under certain
non-fundamental investment limitations that  may be changed without  shareholder
approval.   For  additional  information   on  fundamental  and  non-fundamental
investment  limitations,  see  "Investment  Limitations"  in  the  Statement  of
Additional Information.
 
                             MANAGEMENT OF THE FUND
 
    INVESTMENT ADVISER.  Morgan Stanley Asset Management Inc. is the Adviser and
Administrator  of the Fund  and each Portfolio.  The Adviser provides investment
advice and portfolio  management services,  pursuant to  an Investment  Advisory
Agreement  and, subject  to the  supervision of  the Fund's  Board of Directors,
makes each of the Portfolio's day-to-day investment decisions, arranges for  the
execution   of  portfolio  transactions  and   generally  manages  each  of  the
Portfolio's investments. The Adviser is entitled to receive from the  Technology
Portfolio  an annual  management fee, payable  quarterly, equal to  1.00% of the
average daily net assets of the
 
                                       19
<PAGE>
Portfolio. The Adviser has agreed to a  reduction in the fees payable to it  and
to  reimburse the Portfolio, if necessary, if such fees would cause total annual
operating expenses of  the Portfolio to  exceed 1.25% of  the average daily  net
assets of the Class A shares of the Portfolio and 1.50% of the average daily net
assets of the Class B shares of the Portfolio.
 
   
    The  Adviser, with  principal offices  at 1221  Avenue of  the Americas, New
York, New York  10020, conducts  a worldwide portfolio  management business  and
provides  a broad  range of  portfolio management  services to  customers in the
United States and  abroad. On February  5, 1997, Morgan  Stanley Group Inc.  and
Dean  Witter, Discover & Co.  announced that they had  entered into an Agreement
and Plan of Merger to  form Morgan Stanley, Dean  Witter, Discover & Co.  Morgan
Stanley  Group Inc.  is the  direct parent  of the  Adviser and  Morgan Stanley.
Subject to certain conditions  being met, it is  currently anticipated that  the
transaction  will close in mid-1997. Thereafter,  the Adviser and Morgan Stanley
will be subsidiaries of Morgan Stanley, Dean Witter, Discover & Co. At March 31,
1997, the  Adviser, together  with its  affiliated asset  management  companies,
managed  investments totaling in excess of $118 billion, including approximately
$100 billion  under active  management and  $18 billion  as Named  Fiduciary  or
Fiduciary  Adviser. See "Management of the  Fund" in the Statement of Additional
Information.
    
 
    PORTFOLIO MANAGER.    CHRISTOPHER R.  BLAIR.  Christopher Blair  joined  the
Adviser  in  1993  as  the Technology  and  Telecommunications  Analyst  for the
emerging growth stock group. Previously, he had been a Financial Analyst for two
years in Morgan Stanley's Corporate Finance Department, where he focused on  the
telecommunications  and technology sectors. Mr. Blair graduated with distinction
from McGill  University, where  he  received a  B.A.  in Political  Science  and
Economics. Mr. Blair has had primary management responsibility for the Portfolio
since its inception.
 
    ADMINISTRATOR.   The  Adviser also  provides administrative  services to the
Fund pursuant to an  Administration Agreement. The  services provided under  the
Administration  Agreement are subject to the supervision of the Officers and the
Board of Directors of the Fund and include day-to-day administration of  matters
related  to the  corporate existence  of the  Fund, maintenance  of its records,
preparation  of  reports,  supervision  of  the  Fund's  arrangements  with  its
custodian   and  assistance  in  the  preparation  of  the  Fund's  registration
statements under federal laws. The  Administration Agreement also provides  that
the Administrator, through its agents, will provide the Fund dividend disbursing
and   transfer  agent  services  to  the   Fund.  For  its  services  under  the
Administration Agreement, the Fund  pays the Adviser a  monthly fee which on  an
annual basis equals 0.15% of the average daily net assets of the Portfolio.
 
   
    Under  an  agreement  between  the  Adviser  and  The  Chase  Manhattan Bank
("Chase"), Chase provides  certain administrative services  to the Fund  through
its  corporate  affiliate, Chase  Global Funds  Services Company  ("CGFSC"). The
Adviser supervises and monitors such administrative services provided by  CGFSC.
Their  services are also subject to the supervision of the Board of Directors of
the Fund. CGFSC's business address  is 73 Tremont Street, Boston,  Massachusetts
02108-3913.
    
 
    DIRECTORS  AND OFFICERS.  Pursuant to  the Fund's Articles of Incorporation,
the Board of Directors  decides upon matters of  general policy and reviews  the
actions  of  the Fund's  Adviser, Administrator,  Distributor and  other service
providers. The Officers  of the Fund  conduct and supervise  its daily  business
operations.
 
                                       20
<PAGE>
    DISTRIBUTOR.   Morgan  Stanley serves  as the  exclusive Distributor  of the
shares of  the Fund.  Under its  Distribution Agreement  with the  Fund,  Morgan
Stanley sells shares of the Portfolio upon the terms and at the current offering
price  described in this Prospectus. Morgan Stanley is not obligated to sell any
certain number of shares of any Portfolio.
 
    The Portfolio currently offers  only the classes of  shares offered by  this
Prospectus.  The Portfolio may in the future offer one or more classes of shares
with features, distribution expenses or  other expenses that are different  from
those of the classes currently offered.
 
    The  Fund has  adopted a Plan  of Distribution  with respect to  the Class B
shares pursuant to Rule 12b-1 under the  1940 Act (the "Plan"). Under the  Plan,
the  Distributor is entitled  to receive from the  Portfolio a distribution fee,
which is accrued  daily and  paid quarterly,  of 0.25%  of the  Class B  shares'
average  daily net  assets on  an annualized  basis. The  Distributor expects to
reallocate most of its  fee to its  investment representatives. The  Distributor
may,  in its discretion, voluntarily waive from  time to time all or any portion
of its distribution fee and each of  the Distributor and the Adviser is free  to
make  additional payments  out of  its own  assets to  promote the  sale of Fund
shares,  including   payments  that   compensate  financial   institutions   for
distribution services or shareholder services.
 
    The  Plan is designed to compensate the Distributor for its services, not to
reimburse the Distributor for its expenses,  and the Distributor may retain  any
portion  of the fee that it does not expend in fulfillment of its obligations to
the Fund.
 
    EXPENSES.  The Portfolio  is responsible for payment  of certain other  fees
and  expenses  (including  legal  fees, accountants'  fees,  custodial  fees and
printing and mailing  costs) specified  in the  Administration and  Distribution
Agreements.
 
                               PURCHASE OF SHARES
 
    Class  A and  Class B shares  of the Portfolio  may be purchased  at the net
asset value per share next determined after receipt of the purchase order by the
Portfolio. See "Valuation of Shares."
 
MINIMUM INVESTMENT AND ACCOUNT SIZES; CONVERSION FROM CLASS A TO CLASS B SHARES
 
    For a Portfolio account, the minimum initial investment and minimum  account
size  are $250,000 for  Class A shares  and $50,000 for  Class B shares. Certain
advisory or asset allocation accounts, such as Total Funds Management  accounts,
managed  by Morgan  Stanley or its  affiliates, including  the Adviser ("Managed
Accounts") may purchase  Class A shares  without being subject  to such  minimum
initial investment or minimum account size requirements for a Portfolio account.
Employees  of the  Adviser and  certain of its  affiliates may  purchase Class A
shares subject  to conditions,  including a  lower minimum  initial  investment,
established by Officers of the Fund.
 
    If  the value of a  Portfolio account containing Class  A shares falls below
$250,000 (but remains at or above $50,000) because of shareholder redemption(s),
the Fund will  notify the shareholder,  and if the  account value remains  below
$250,000  (but remains at or above $50,000)  for a continuous 60-day period, the
Class A  shares in  such account  will convert  to Class  B shares  and will  be
subject  to the distribution  fee and other  features applicable to  the Class B
shares. The Fund, however,  will not convert  Class A shares  to Class B  shares
based
 
                                       21
<PAGE>
solely  upon changes in  the market that  reduce the net  asset value of shares.
Under current tax law, conversions between share classes are not a taxable event
to the shareholder. Managed Accounts are not subject to conversion from Class  A
shares to Class B shares.
 
    Investors  may also invest  in the Portfolio by  purchasing shares through a
trust department, broker, dealer,  agent, financial planner, financial  services
firm  or investment adviser. An investor may be charged an additional service or
transaction fee by that institution.
 
   
    The minimum investment levels may be waived at the discretion of the Adviser
for (i) certain employees and customers of Morgan Stanley or its affiliates  and
certain   trust  departments,  brokers,  dealers,  agents,  financial  planners,
financial services  firms, or  investment  advisers that  have entered  into  an
agreement  with  Morgan  Stanley  or its  affiliates;  and  (ii)  retirement and
deferred compensation plans and trusts used  to fund such plans, including,  but
not  limited to, those defined in Section 401(a),  403(b) or 457 of the Code and
"rabbi trusts."  The  Fund  reserves  the  right  to  modify  or  terminate  the
conversion  features of  the shares  as stated  above at  any time  upon 60-days
notice to shareholders.
    
 
    The Adviser reserves the right in its sole discretion to determine which  of
such  advisory  or  asset allocation  accounts  shall be  Managed  Accounts. For
information regarding  Managed  Accounts,  please contact  your  Morgan  Stanley
account representative or the Fund at the telephone number provided on the cover
of this Prospectus.
 
MINIMUM ACCOUNT SIZES AND INVOLUNTARY REDEMPTION OF SHARES
 
    If  the  value  of  a  Portfolio  account  falls  below  $50,000  because of
shareholder redemption(s),  the Fund  will notify  the shareholder,  and if  the
account  value remains below $50,000 for  a continuous 60-day period, the shares
in such account are subject to redemption by the Fund and, if redeemed, the  net
asset  value of such shares will be  promptly paid to the shareholder. The Fund,
however, will not  redeem shares based  solely upon changes  in the market  that
reduce the net asset value of shares.
 
    The  Fund  reserves  the  right  to  modify  or  terminate  the  involuntary
redemption features  of the  shares as  stated above  at any  time upon  60-days
notice to shareholders.
 
CONVERSION FROM CLASS B TO CLASS A SHARES
 
    If the value of Class B shares in a Portfolio account increases, whether due
to  shareholder share  purchases or  market activity,  to $250,000  or more, the
Class B shares  will convert  to Class  A shares.  Under current  tax law,  such
conversion  is not a taxable event to  the shareholder. Class A shares converted
from Class B shares  are subject to the  same minimum account size  requirements
that  are applicable to Portfolio accounts  containing Class A shares, as stated
above. The  Fund reserves  the  right to  modify  or terminate  this  conversion
feature at any time upon 60-days notice to shareholders.
 
INITIAL PURCHASES DIRECTLY FROM THE FUND
 
    The  Fund's determination of an investor's eligibility to purchase shares of
a given class  will take precedence  over the investor's  selection of a  class.
Assuming  the investor is eligible for the  class, the Fund will select the most
favorable class for the investor, if the investor has not done so.
 
                                       22
<PAGE>
INITIAL INVESTMENTS
 
1) BY CHECK.   An account may  be opened  by completing and  signing an  Account
   Registration Form and mailing it, together with a check ($250,000 minimum for
   Class  A  shares of  the  Portfolio and  $50,000 for  Class  B shares  of the
   Portfolio, with certain  exceptions for Morgan  Stanley employees and  select
   customers)  payable to "Morgan Stanley Institutional Fund, Inc. -- [portfolio
   name]" to:
 
      Morgan Stanley Institutional Fund, Inc.
      P.O. Box 2798
      Boston, Massachusetts 02208-2798
 
   
Payment will be accepted only in U.S. dollars, unless prior approval for payment
by other currencies is given by the Fund. The classes of shares of the Portfolio
to be  purchased should  be designated  on the  Account Registration  Form.  For
purchases  by check, the  Fund is ordinarily credited  with Federal Funds within
one business day. Thus, your purchase of shares by check is ordinarily  credited
to  your account at the net asset value per share of the Portfolio determined on
the next business day after receipt.
    
 
2) BY FEDERAL  FUNDS WIRE.   Purchases  may be  made by  having your  bank  wire
   Federal  Funds to the Fund's bank account.  In order to ensure prompt receipt
   of your Federal Funds Wire, it is important that you follow these steps:
 
  A.  Telephone the Fund (toll  free: 1-800-548-7786) and  provide us with  your
      name,  address, telephone  number, Social  Security or  Tax Identification
      Number, the portfolio(s)  selected, the class  selected, the amount  being
      wired,  and by which  bank. We will  then provide you  with a Fund account
      number. (Investors  with existing  accounts should  also notify  the  Fund
      prior to wiring funds.)
 
                                       23
<PAGE>
  B.  Instruct  your  bank  to wire  the  specified  amount to  the  Fund's Wire
      Concentration Bank Account (be sure to have your bank include the name  of
      the  portfolio(s)  selected, the  class  selected and  the  account number
      assigned to you) as follows:
 
   
      The Chase Manhattan Bank
    
      One Manhattan Plaza
      New York, NY 10081-1000
      ABA #021000021
      DDA #910-2-733293
      Attn: Morgan Stanley Institutional Fund, Inc.
      Ref: (Portfolio name, your account number, your account name)
 
      Please call the Fund at 1-800-548-7786 prior to wiring funds.
 
  C.  Complete and sign the Account Registration Form and mail it to the address
      shown thereon.
 
   The purchase price of the Class A and Class B shares of the Portfolio is  the
   net  asset value next determined after  the order is received. See "Valuation
   of Shares."  An order  received prior  to the  close of  the New  York  Stock
   Exchange  ("NYSE"),  which  is  currently 4:00  p.m.  Eastern  Time,  will be
   executed at the  price computed  on the date  of receipt;  an order  received
   after the regular close of the NYSE will be executed at the price computed on
   the  next day the NYSE is open as long as the Transfer Agent receives payment
   by check or in Federal Funds prior to  the regular close of the NYSE on  such
   day.
 
Federal  Funds purchase orders will be accepted only  on a day on which the Fund
and Chase (the "Custodian Bank") are open  for business. Your bank may charge  a
service fee for wiring Federal Funds.
 
3) BY  BANK WIRE.   The  same procedure outlined  under "By  Federal Funds Wire"
   above must be  followed in  purchasing shares  by bank  wire. However,  money
   transferred  by bank wire may or may  not be converted into Federal Funds the
   same day, depending on the time the  money is received and the bank  handling
   the  wire. Prior to such conversion, an investor's money will not be invested
   and, therefore, will not be earning dividends. Your bank may charge a service
   fee for wiring funds.
 
ADDITIONAL INVESTMENTS
 
    You may  add to  your account  at any  time (minimum  additional  investment
$1,000,  except  for  automatic  reinvestment  of  dividends  and  capital gains
distributions for which there are no minimums) by purchasing shares at net asset
value by mailing a check to  the Fund (payable to "Morgan Stanley  Institutional
Fund, Inc. -- [portfolio name]") at the above address or by wiring monies to the
Custodian  Bank as outlined above. It is  very important that your account name,
the portfolio name and the class selected be specified in the letter or wire  to
assure  proper crediting  to your  account. In  order to  ensure that  your wire
orders are invested  promptly, you  are requested to  notify one  of the  Fund's
representatives  (toll-free 1-800-548-7786)  prior to the  wire date. Additional
investments will be applied to purchase additional shares in the same class held
by a shareholder in a Portfolio account.
 
OTHER PURCHASE INFORMATION
 
    Although the legal rights of Class A  and Class B shares will be  identical,
the  different expenses borne by  each class will result  in different net asset
values and dividends. The net  asset value of Class  B shares will generally  be
lower than the net asset value of Class A shares as a result of the distribution
expense charged to
 
                                       24
<PAGE>
Class  B shares. It is expected, however, that  the net asset value per share of
the two  classes  will tend  to  converge  immediately after  the  recording  of
dividends  which will  differ by  approximately the  amount of  the distribution
expense accrual differential between the classes.
 
   
    In the interest  of economy and  convenience, and because  of the  operating
procedures  of the Fund, certificates representing  shares of the Portfolio will
not be issued. All shares  purchased are confirmed to  you and credited to  your
account  on the Fund's books  maintained by the Adviser  or its agents. You will
have  the  same  rights  and  ownership  with  respect  to  such  shares  as  if
certificates had been issued.
    
 
    To  ensure that checks are collected by the Fund, withdrawals of investments
made by check  are not presently  permitted until payment  for the purchase  has
been  received,  which may  take up  to eight  business days  after the  date of
purchase. As a condition  of this offering,  if a purchase  is cancelled due  to
nonpayment or because your check does not clear, you will be responsible for any
loss  the Fund or its  agents incur. If you are  already a shareholder, the Fund
may redeem shares from your account(s) to  reimburse the Fund or its agents  for
any  loss. In addition, you  may be prohibited or  restricted from making future
investments in the Fund.
 
    Investors may  also invest  in the  Fund by  purchasing shares  through  the
Distributor.
 
EXCESSIVE TRADING
 
   
    Frequent   trades  involving  either  substantial   portfolio  assets  or  a
substantial portion of your  account or accounts controlled  by you can  disrupt
management  of a Portfolio and raise its expenses. Consequently, in the interest
of all the stockholders  of the Portfolio and  the Portfolio's performance,  the
Fund  may in its discretion bar a  stockholder that engages in excessive trading
of shares of any class  of a portfolio from further  purchases of shares of  the
Fund  for an indefinite period. The Fund  considers excessive trading to be more
than one purchase and sale involving shares of the same class of a Portfolio  of
the  Fund  within  any  120-day  period. As  an  example,  exchanging  shares of
portfolios of  the Fund  as  follows amounts  to excessive  trading:  exchanging
shares  of Portfolio  A for  shares of  Portfolio B,  then exchanging  shares of
Portfolio B for shares of Portfolio C and again exchanging shares of Portfolio C
for shares of Portfolio B within a 120-day period. Two types of transactions are
exempt from these excessive trading restrictions: (1) trades exclusively between
money market  portfolios;  and (2)  trades  done  in connection  with  an  asset
allocation  service, such as TFM Accounts or  accounts managed or advised by the
Adviser and/or any of its affiliates.
    
 
INVESTMENT IN FUNDS THROUGH A TOTAL FUNDS MANAGEMENT ("TFM") ACCOUNT
 
   
    In addition to the considerable diversification among individual  securities
you  receive by investing in a particular Portfolio, you can further reduce risk
by spreading  your assets  among  several different  Portfolios that  each  have
different   risk  and  return  characteristics.  TFM  is  an  active  investment
management service managed by Morgan Stanley or its affiliates, including Morgan
Stanley Asset  Management Inc.  (each,  a "TFM  Adviser"), that  allocates  your
investments  across a combination of either Class A or Class B shares of certain
of the Portfolios selected to meet your long-term investment objectives as  well
as, in certain circumstances, your current income objectives.
    
 
    The TFM Adviser has developed investment strategies for TFM Accounts to meet
the  diverse financial needs of different investors.  You can open a TFM Account
by meeting with one  of the investment professionals  of a Participating  Dealer
who  will review your situation and  help you identify your long-term investment
and/or current income  objectives. After  using TFM criteria  to determine  your
long-term investment and/or current
 
                                       25
<PAGE>
   
income  objectives, you  can choose  one of  several TFM  investment strategies.
Based on your chosen strategy, your initial investment will be allocated among a
number of the Class A or Class  B shares of the Portfolios. Depending on  market
conditions,   the  TFM  Adviser  periodically  reallocates  the  combination  of
Portfolios or the percentage amounts invested in the shares of each Portfolio to
implement your TFM investment  strategy. In addition, your  TFM Account will  be
periodically rebalanced to maintain your TFM strategy's current asset allocation
mix, if and when the performance of one or more of the Portfolios unbalances the
strategy's  mix. You will pay the TFM Adviser  a fee for the TFM Account service
that is in  addition to and  separate from the  fees and expenses  you will  pay
directly or indirectly as an investor in the Portfolios. See "Fund Expenses."
    
 
   
    From  time to time, one or more of the Portfolios used for investment by the
TFM Accounts may experience relatively  large investments or redemptions due  to
the  TFM Account  allocations or  rebalancings recommended  by the  TFM Adviser.
These transactions will affect the  Portfolios since Portfolios that  experience
redemptions  as  a result  of  reallocations or  rebalancings  may have  to sell
portfolio securities and Portfolios  that receive additional  cash will have  to
invest  it in additional portfolio securities. While it is impossible to predict
the overall  impact of  these transactions  over time,  there could  be  adverse
effects on portfolio management to the extent that Portfolios may be required to
sell  securities or invest  cash at times  when they would  not otherwise do so.
These transactions  could also  have  tax consequences  if sales  of  securities
resulted  in  gains  and could  also  increase transaction  costs.  The Adviser,
representing the interests  of the  Portfolios, is committed  to minimizing  the
impact of TFM Account transactions on the Portfolios. The Adviser, however, will
have  a conflict in fulfilling  this responsibility in that  it also serves as a
TFM Adviser. In that  capacity, the Adviser, representing  the interests of  the
TFM  Accounts,  also  is  committed  to minimizing  the  impact  of  TFM Account
transactions on  the  Portfolios to  the  extent consistent  with  pursuing  the
investment  objectives of the TFM Accounts. In addition, an affiliate of the TFM
Adviser, the Distributor is compensated on the sale, and may be compensated  for
distribution  or shareholder services  on the sale of  shares of the Portfolios.
See "Purchase of Shares"  and "Shareholder Services  -- Exchange Features."  The
Adviser will monitor the impact of TFM Account transactions on the Portfolios.
    
 
                              REDEMPTION OF SHARES
 
    You  may  withdraw all  or  any portion  of the  amount  in your  account by
redeeming shares at any time. Please note  that purchases made by check are  not
permitted  to  be redeemed  until the  payment  of the  purchase price  has been
collected, which may  take up to  eight business days  after purchase. The  Fund
will  redeem Class  A shares  or Class  B shares  of the  Portfolio at  the next
determined net asset value of shares of the applicable class. On days that  both
the  NYSE and the Custodian Bank are open  for business, the net asset value per
share of the Portfolio is determined at the regular close of trading of the NYSE
(currently 4:00 p.m. Eastern Time). Shares  of the Portfolio may be redeemed  by
mail or telephone. No charge is made for redemption. Any redemption proceeds may
be more or less than the purchase price of your shares depending on, among other
factors, the market value of the investment securities held by the Portfolio.
 
BY MAIL
 
    The  Portfolio will redeem its  Class A shares or Class  B shares at the net
asset value determined on the  date the request is  received, if the request  is
received   in  "good  order"  before  the   regular  close  of  the  NYSE.  Your
 
                                       26
<PAGE>
request should be addressed to Morgan Stanley Institutional Fund, Inc., P.O. Box
2798, Boston, MA 02208-2798, except that deliveries by overnight courier  should
be  addressed to Morgan Stanley Institutional Fund, Inc., c/o Chase Global Funds
Services Company, 73 Tremont Street, Boston, MA 02108-3913.
 
    "Good order"  means that  the  request to  redeem  shares must  include  the
following documentation:
 
       (a) A  letter of instruction  or a stock  assignment specifying the class
           and number of shares or dollar  amount to be redeemed, signed by  all
    registered  owners  of the  shares  in the  exact  names in  which  they are
    registered;
 
       (b) Any  required   signature   guarantees   (see   "Further   Redemption
           Information" below); and
 
       (c) Other  supporting  legal  documents,  if  required,  in  the  case of
           estates, trusts, guardianships, custodianships, corporations, pension
    and profit-sharing plans and other organizations.
 
    Shareholders who are uncertain of requirements for redemption should consult
with a Fund representative.
 
BY TELEPHONE
 
    Provided you have previously elected the Telephone Redemption Option on  the
Account  Registration  Form, you  can  request a  redemption  of your  shares by
calling the Fund  and requesting  the redemption proceeds  be mailed  to you  or
wired to your bank. Please contact one of the Fund's representatives for further
details.  In times of drastic market conditions, the telephone redemption option
may be  difficult  to  implement.  If you  experience  difficulty  in  making  a
telephone  redemption, your request may be made  by regular mail or express mail
and it will be implemented  at the net asset value  next determined after it  is
received.  Redemption requests  sent to  the Fund  through express  mail must be
mailed to the address of the Dividend Disbursing and Transfer Agent listed under
"General Information." The  Fund and  the Fund's transfer  agent (the  "Transfer
Agent")  will  employ reasonable  procedures  to confirm  that  the instructions
communicated by telephone  are genuine. These  procedures include requiring  the
investor  to provide certain personal identification  information at the time an
account  is  opened  and  prior  to  effecting  each  transaction  requested  by
telephone.  In addition, all telephone transaction requests will be recorded and
investors may be required to provide additional telecopied written  instructions
regarding  transaction requests. Neither the Fund nor the Transfer Agent will be
responsible for any loss, liability, cost or expense for following  instructions
received by telephone that either of them reasonably believes to be genuine.
 
    To  change the commercial  bank or account  designated to receive redemption
proceeds, a written  request must  be sent  to the  Fund at  the address  above.
Requests  to change the bank  or account must be  signed by each shareholder and
each signature must be guaranteed.
 
FURTHER REDEMPTION INFORMATION
 
    Normally the  Fund will  make payment  for all  shares redeemed  within  one
business  day of receipt  of the request, but  in no event  will payment be made
more than  seven days  after receipt  of  a redemption  request in  good  order.
However,  payments to investors  redeeming shares which  were purchased by check
will not be made until  payment for the purchase  has been collected, which  may
take up to eight days after the date of purchase. The Fund may suspend the right
of  redemption or postpone the date upon which redemptions are effected at times
when the NYSE is closed, or  under any emergency circumstances as determined  by
the Securities and Exchange Commission (the "Commission").
 
                                       27
<PAGE>
    If  the Board of  Directors determines that  it would be  detrimental to the
best interests of the  remaining shareholders of the  Portfolio to make  payment
wholly  or partly in cash, the Fund may  pay the redemption proceeds in whole or
in part by a distribution in-kind of securities held by the Portfolio in lieu of
cash   in    conformity   with    applicable    rules   of    the    Commission.
Distributions-in-kind  will be made in  readily marketable securities. Investors
may incur brokerage charges on the  sale of portfolio securities so received  in
payment of redemptions.
 
    To  protect  your account,  the Fund  and its  agents from  fraud, signature
guarantees are required for  certain redemptions to verify  the identity of  the
person  who has  authorized a redemption  from your account.  Please contact the
Fund for further  information. See "Redemption  of Shares" in  the Statement  of
Additional Information.
 
                              SHAREHOLDER SERVICES
 
EXCHANGE FEATURES
 
    You  may exchange  shares that you  own in  the Portfolio for  shares of any
other available portfolio(s) of  the Fund (other  than the International  Equity
Portfolio,  which is  closed to  new investors). In  exchanging for  shares of a
portfolio with more  than one  class, the  class of  shares you  receive in  the
exchange  will be determined in the same  manner as any other purchase of shares
and will not  be based  on the  class of  shares surrendered  for the  exchange.
Consequently,  the same minimum initial investment  and minimum account size for
determining the  class  of shares  received  in  the exchange  will  apply.  See
"Purchase  of Shares."  Shares of  the portfolios  may be  exchanged by  mail or
telephone. The privilege to exchange shares  by telephone is automatic and  made
available  without shareholder election. Before you make an exchange, you should
read the prospectus of the portfolio(s) in which you seek to invest. Because  an
exchange  transaction  is treated  as a  redemption followed  by a  purchase, an
exchange would be considered  a taxable event for  shareholders subject to  tax.
The  exchange privilege may  be modified or  terminated by the  Fund at any time
upon 60-days notice to shareholders.
 
BY MAIL
 
    In order to  exchange shares  by mail, you  should include  in the  exchange
request  the name, class of shares and account number of your current Portfolio,
the name(s) of the portfolio(s) and class(es) of shares into which you intend to
exchange shares, and the signatures of all registered account holders. Send  the
exchange  request to  Morgan Stanley  Institutional Fund,  Inc., P.O.  Box 2798,
Boston, Massachusetts 02208-2798.
 
BY TELEPHONE
 
   
    When exchanging shares by  telephone, have ready the  name, class of  shares
and account number of the Portfolio, the names of the portfolio(s) and class(es)
of  shares into which you intend to exchange shares, your Social Security number
or Tax I.D. number, and your  account address. Requests for telephone  exchanges
received  prior  to 4:00  p.m.  (Eastern Time)  are  processed at  the  close of
business that same  day based on  the net asset  value of the  class(es) of  the
portfolios involved in the exchange of shares at the close of business. Requests
received  after 4:00  p.m. (Eastern  Time) are  processed the  next business day
based on the net asset  value determined at the close  of business on such  day.
For  additional  information regarding  responsibility  for the  authenticity of
telephoned instructions, see "Redemption of Shares -- By Telephone" above.
    
 
                                       28
<PAGE>
TRANSFER OF REGISTRATION
 
    You may transfer the registration of any of your Portfolio shares to another
person by writing  to Morgan Stanley  Institutional Fund, Inc.,  P.O. Box  2798,
Boston,  MA 02208-2798. As in the case  of redemptions, the written request must
be received in  good order  before any transfer  can be  made. Transferring  the
registration  of shares may affect  the eligibility of your  account for a given
class of the  Portfolio's shares  and may  result in  involuntary conversion  or
redemption of your shares. See "Purchase of Shares" above.
 
                              VALUATION OF SHARES
 
   
    The  net asset  value per  share of a  class of  shares of  the Portfolio is
determined by dividing the total market value of the Portfolio's investments and
other assets attributable to  such class, less  any liabilities attributable  to
such  class, by  the total  number of  outstanding shares  of such  class of the
Portfolio. Net  asset value  is  calculated separately  for  each class  of  the
Portfolio.  Net asset value per  share is determined as  of the regular close of
the NYSE on each day  that the NYSE is open  for business. Price information  on
listed  securities is  taken from the  exchange where the  security is primarily
traded. Securities  listed  on  a  U.S. securities  exchange  for  which  market
quotations are available are valued at the last quoted sale price on the day the
valuation  is made. Securities listed on a  foreign exchange are valued at their
closing price.  Unlisted securities  and  listed securities  not traded  on  the
valuation date for which market quotations are readily available are valued at a
price  within a range  not exceeding the  current asked price  nor less than the
current bid price. The current bid and asked prices are determined based on  the
average  of the bid and asked prices  quoted on such valuation date by reputable
brokers.
    
 
    Bonds and other fixed income securities are valued according to the broadest
and most representative  market, which will  ordinarily be the  over-the-counter
market.  Net asset value includes interest  on fixed income securities, which is
accrued daily.  In addition,  bonds and  other fixed  income securities  may  be
valued on the basis of prices provided by a pricing service when such prices are
believed  to  reflect  the fair  market  value  of such  securities.  The prices
provided by a pricing service are determined without regard to bid or last  sale
prices,  but take into account institutional  size, trading in similar groups of
securities and any developments related  to the specific securities.  Securities
not  priced in this manner  are valued at the most  recently quoted bid price or
when securities exchange valuations are used, at the latest quoted sale price on
the day of valuation. If there is  no such reported sale, the latest quoted  bid
price will be used. Securities purchased with remaining maturities of 60 days or
less are valued at amortized cost, if it approximates market value. In the event
that  amortized  cost  does  not  approximate  market  value,  market  prices as
determined above will be used.
 
   
    The value  of other  assets  and securities  for  which quotations  are  not
readily  available (including  restricted and  unlisted foreign  securities) and
those securities for which it is inappropriate to determine prices in accordance
with the above-stated procedure are determined in good faith at fair value using
methods determined by the  Board of Directors. For  purposes of calculating  net
asset value per share, all assets and liabilities initially expressed in foreign
currencies will be translated into U.S. dollars at the mean of the bid and asked
price of such currencies against the U.S. dollar last quoted by any major bank.
    
 
    Although  the legal rights of Class A  and Class B shares will be identical,
the different expenses borne  by each class will  result in different net  asset
values    and   dividends   for   the    class.   Dividends   will   differ   by
 
                                       29
<PAGE>
approximately the amount of the distribution expense accrual differential  among
the  classes. The net asset value of Class B shares will generally be lower than
the net  asset value  of the  Class A  shares as  a result  of the  distribution
expense charged to Class B shares.
 
                            PERFORMANCE INFORMATION
 
    The  Fund may from time to time advertise total return for each class of the
Portfolio. THESE FIGURES ARE BASED ON  HISTORICAL EARNINGS AND ARE NOT  INTENDED
TO INDICATE FUTURE PERFORMANCE.
 
    "Total  return" shows what an  investment in a class  of the Portfolio would
have earned over a specified  period of time (such as  one, five or ten  years),
assuming  that all distributions and dividends  by the Portfolio were reinvested
in the same class on the reinvestment dates during the period. Total return does
not take into account any federal or  state income taxes that may be payable  on
dividends  and  distributions  or  on  redemption.  The  Fund  may  also include
comparative performance information in advertising or marketing the  Portfolio's
shares,  including data  from Lipper  Analytical Services,  Inc., other industry
publications, business periodicals, rating services and market indices.
 
    The performance figures  for Class  B shares  will generally  be lower  than
those  for Class  A shares because  of the  distribution fee charged  to Class B
shares.
 
                   DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS
 
    All income dividends and capital gains  distributions for a class of  shares
will be automatically reinvested in additional shares at net asset value, except
that,  upon written notice to the Fund or by checking off the appropriate box in
the Distribution Option Section on the Account Registration Form, a  shareholder
may elect to receive income dividends and capital gains distributions in cash.
 
   
    The  Portfolio expects  to distribute substantially  all of  its taxable net
investment income in the form of  annual dividends. Net realized capital  gains,
if  any, after reduction for  any available tax loss  carryforwards will also be
distributed annually.
    
 
    Undistributed net  investment  income is  included  in the  Portfolio's  net
assets  for the purpose of calculating net  asset value per share. Therefore, on
the "ex-dividend" date,  the net  asset value  per share  excludes the  dividend
(i.e.,  is reduced  by the  per share  amount of  the dividend).  Dividends paid
shortly after the purchase of shares by an investor, although in effect a return
of capital, are taxable to shareholders subject to income tax.
 
    Because of  the  distribution  fee  and  any  other  expenses  that  may  be
attributable  to the  Class B  shares, the  net income  attributable to  and the
dividends payable  on  Class  B  shares  will  be  lower  than  the  net  income
attributable  to and the dividends  payable on Class A  shares. As a result, the
net asset value per share of the classes of the Portfolio will differ at  times.
Expenses  of the  Portfolio allocated  to a particular  class of  shares will be
borne on a pro rata basis by each outstanding share of that class.
 
                                     TAXES
 
    The following summary of certain federal income tax consequences is based on
current tax laws and regulations, which may be changed by legislative, judicial,
or administrative action.
 
                                       30
<PAGE>
    No attempt has been made to  present a detailed explanation of the  federal,
state,  or  local income  tax treatment  of the  Portfolio or  its shareholders.
Accordingly, shareholders  are urged  to consult  their tax  advisers  regarding
specific questions as to federal, state and local income taxes.
 
    The  Portfolio  is  treated as  a  separate  entity for  federal  income tax
purposes and is  not combined with  the Fund's other  portfolios. The  Portfolio
intends  to qualify for the special  tax treatment afforded regulated investment
companies under Subchapter M of the Code, so that the Portfolio will be relieved
of federal income tax on that part of its net investment income and net  capital
gain that is distributed to shareholders.
 
   
    The  Portfolio intends  to distribute substantially  all of  its taxable net
investment income (including,  for this  purpose, the excess  of net  short-term
capital  gain over net  long-term capital loss)  to shareholders. Dividends from
the Portfolio's net investment  income are taxable  to shareholders as  ordinary
income, whether received in cash or in additional shares. Such dividends paid by
the  Portfolio will generally  qualify for the  70% dividends-received deduction
for corporate shareholders to the extent of qualifying dividend income  received
by  the Portfolio from U.S. corporations.  The Portfolio will report annually to
its shareholders the amount of dividend income qualifying for such treatment.
    
 
    Distributions of net capital gains (the excess of net long-term capital gain
over net  short-term capital  loss)  are taxable  to shareholders  as  long-term
capital  gain, regardless of  how long the shareholder  has held the Portfolio's
shares. The Portfolio will send reports annually to shareholders of the  federal
income tax status of all distributions made during the preceding year.
 
    The   Portfolio  intends   to  make   sufficient  distributions   or  deemed
distributions of its ordinary income and capital gain net income (the excess  of
short-term  and  long-term capital  gain over  short-term and  long-term capital
loss, including any available capital loss  carryforwards), prior to the end  of
each calendar year to avoid liability for federal excise tax.
 
    Dividends  and  other distributions  declared by  the Portfolio  in October,
November or December of any year and payable to shareholders of record on a date
in such month will be deemed to have been paid by the Portfolio and received  by
the  shareholders in that year if the distributions are paid by the Portfolio at
any time during the following January.
 
   
    The Fund may be required to withhold  and remit to the U.S. Treasury 31%  of
any  dividends, capital gains distributions and  redemption proceeds paid to any
individual or  certain other  non-corporate shareholder  (1) who  has failed  to
provide  a  correct taxpayer  identification  number (generally  an individual's
social security number  or non-individual's employer  identification number)  on
the  Application Form, (2) who is subject  to backup withholding by the Internal
Revenue Service, or (3) who has not certified to the Fund that such  shareholder
is  not  subject  to  backup  withholding. This  backup  withholding  is  not an
additional  tax,  and  any  amounts   withheld  may  be  credited  against   the
shareholder's ultimate U.S. tax liability.
    
 
    The  sale, redemption or exchange  of shares will result  in taxable gain or
loss to the selling, redeeming or exchanging shareholder, depending upon whether
the fair market value of the sale, redemption or exchange proceeds exceed or  is
less  than the shareholder's  adjusted basis in the  sold, redeemed or exchanged
shares. If capital gain distributions have been made with respect to shares that
are sold at a  loss after being held  for six months or  less, then the loss  is
treated  as  a  long-term  capital  loss  to  the  extent  of  the  capital gain
distributions.
 
    Conversion  of  shares  between  classes  are  not  taxable  events  to  the
shareholder.
 
                                       31
<PAGE>
    Shareholders  are urged  to consult with  their tax  advisers concerning the
application of state  and local income  taxes to investments  in the  Portfolio,
which may differ from the federal income tax consequences described above.
 
    THE TAX DISCUSSION SET FORTH ABOVE IS INCLUDED FOR GENERAL INFORMATION ONLY.
PROSPECTIVE  INVESTORS SHOULD CONSULT THEIR OWN TAX ADVISERS WITH RESPECT TO THE
TAX CONSEQUENCES TO THEM OF AN INVESTMENT IN THE PORTFOLIO.
 
                             PORTFOLIO TRANSACTIONS
 
    The Adviser selects the brokers or  dealers that will execute the  purchases
and  sales  of investment  securities  for each  of  the Fund's  portfolios. The
Adviser seeks the best execution of all portfolio transactions. A portfolio  may
pay  higher commission rates than the lowest available when the Adviser believes
it is reasonable to do  so in light of the  value of the research,  statistical,
and pricing services provided by the broker effecting the transaction.
 
    It is not the Fund's practice to allocate brokerage or principal business on
the  basis of sales of shares which  may be made through intermediary brokers or
dealers. However, the Adviser may,  consistent with NASD rules, place  portfolio
orders  with qualified broker-dealers who  recommend the applicable portfolio to
their clients or who act  as agents in the purchase  of shares of the  portfolio
for their clients.
 
    Subject  to  the overriding  objective of  obtaining  the best  execution of
orders, the  Fund may  use broker-dealer  affiliates of  the Adviser,  including
Morgan  Stanley,  to effect  portfolio  brokerage transactions  under procedures
adopted by the Fund's Board of Directors. For such transactions, the  commission
rates  and other remuneration paid to Morgan Stanley or other affiliates must be
fair  and  reasonable  in  comparison  to  those  of  other  broker-dealers  for
comparable  transactions involving  similar securities  being purchased  or sold
during a comparable time period.
 
PORTFOLIO TURNOVER
 
   
    The Portfolio generally  does not  invest for  short-term trading  purposes,
however,   when  circumstances  warrant,  the   Portfolio  may  sell  investment
securities without regard  to the  length of time  they have  been held.  Market
conditions  in a given year could result in a higher or lower portfolio turnover
rate than expected and the Portfolio will not consider portfolio turnover rate a
limiting factor in making investment decisions consistent with their  respective
objective  and  policies. As  portfolio  turnover increases,  the  Portfolio may
expect to pay correspondingly increased brokerage and trading costs. In addition
to transaction costs, higher portfolio turnover may result in the realization of
capital gains. As discussed under "Taxes," to the extent net short-term  capital
gains  are realized, any distributions resulting  from such gains are considered
ordinary income for federal income tax purposes.
    
 
                              GENERAL INFORMATION
 
DESCRIPTION OF COMMON STOCK
 
    The Fund  was organized  as a  Maryland corporation  on June  16, 1988.  The
Articles  of Incorporation, as amended and restated, permit the Fund to issue up
to 35 billion shares of common stock,  with $.001 par value per share.  Pursuant
to the Fund's Articles of Incorporation, the Board of Directors may increase the
number of
 
                                       32
<PAGE>
   
shares  the Fund is authorized to issue without the approval of the shareholders
of the Fund.  The Board  of Directors  has the power  to designate  one or  more
classes  of shares of common  stock and to classify  and reclassify any unissued
shares with  respect  to  such classes.  The  shares  of common  stock  of  each
portfolio  are currently classified into two classes, the Class A shares and the
Class B  shares,  except  for  the Money  Market,  Municipal  Money  Market  and
International Small Cap Portfolios, which offers only Class A shares.
    
 
    The shares of the Portfolio, when issued, will be fully paid, nonassessable,
fully  transferable and redeemable at the option  of the holder. The shares have
no preference  as  to  conversion,  exchange,  dividends,  retirement  or  other
features  and  have no  pre-emptive  rights. The  shares  of the  Portfolio have
non-cumulative rights, which  means that  the holders of  more than  50% of  the
shares  voting for the election of Directors  can elect 100% of the Directors if
they choose  to do  so.  Persons or  organizations owning  25%  or more  of  the
outstanding  shares of the Portfolio may be  presumed to "control" (as that term
is defined in the 1940 Act) the  Portfolio. Under Maryland law, the Fund is  not
required  to hold an annual meeting of its shareholders unless required to do so
under the 1940 Act.
 
REPORTS TO SHAREHOLDERS
 
    The Fund will send to its  shareholders annual and semi-annual reports;  the
financial  statements  appearing in  annual reports  are audited  by independent
accountants. Monthly unaudited portfolio  data is also  available from the  Fund
upon request.
 
    In  addition, the Adviser or its agent, as Transfer Agent, will send to each
shareholder having an account directly with the Fund a monthly statement showing
transactions in the account, the total number of shares owned, and any dividends
or distributions paid.
 
CUSTODIAN
 
    Chase is the Fund's Custodian for domestic and certain foreign assets. Chase
is not an  affiliate of  the Adviser or  the Distributor.  Morgan Stanley  Trust
Company,  Brooklyn,  New York  ("MSTC"),  an affiliate  of  the Adviser  and the
Distributor, acts as  the Fund's custodian  for assets held  outside the  United
States  and employs subcustodians approved by the Board of Directors of the Fund
in accordance with regulations of the Securities and Exchange Commission for the
purpose of providing  custodial services  for such  assets. MSTC  may also  hold
certain  domestic assets for  the Fund. For more  information on the custodians,
see "General Information -- Custody Arrangements" in the Statement of Additional
Information.
 
DIVIDEND DISBURSING AND TRANSFER AGENT
 
    Chase  Global   Funds  Services   Company,   73  Tremont   Street,   Boston,
Massachusetts 02108-3913, acts as Dividend Disbursing and Transfer Agent for the
Fund.
 
INDEPENDENT ACCOUNTANTS
 
   
    Price  Waterhouse LLP  serves as  independent accountants  for the  Fund and
audits its annual financial statements.
    
 
LITIGATION
 
    The Fund is not involved in any litigation.
 
                                       33
<PAGE>
   MORGAN STANLEY INSTITUTIONAL FUND, INC.
          TECHNOLOGY PORTFOLIO
           P.O. BOX 2798, BOSTON, MA 02208-2798
 
                           ACCOUNT REGISTRATION FORM
 
<TABLE>
<C>   <S>                        <C>
                                 If you need assistance in filling out this form for the
      ACCOUNT INFORMATION        Morgan Stanley Institutional Fund, please contact your
      Fill in where applicable   Morgan Stanley representative or call us toll free
                                 1-(800)-548-7786. Please print all items except signature,
                                 and mail to the Fund at the address above.
  A)  REGISTRATION
      1. INDIVIDUAL
      2. JOINT TENANTS
         (RIGHTS OF
      SURVIVORSHIP PRESUMED
      UNLESS
         TENANCY IN COMMON
         IS INDICATED)
</TABLE>
 
1.
                               First
Name                          Initial                               Last Name
 
2.
                               First
Name                          Initial                               Last Name
 
                               First
Name                          Initial                               Last Name
 
<TABLE>
<C>   <S>                        <C>
      3. CORPORATIONS,
         TRUSTS AND OTHERS
         Please call the Fund
      for additional documents
      that may be required to
      set up account and to
      authorize transactions.
</TABLE>
 
3.
 
<TABLE>
<S>                     <C>                 <C>                   <C>               <C>
Type of Registration:   / / INCORPORATED    / / UNINCORPORATED    / / PARTNERSHIP   / / UNIFORM GIFT/TRANSFER TO MINOR
                                            ASSOCIATION                               (ONLY ONE CUSTODIAN AND MINOR PERMITTED)
</TABLE>
 
/ / TRUST ________________________  / / OTHER (Specify) ________________________
 
<TABLE>
<C>   <S>                        <C>
  B)  MAILING ADDRESS
      Please fill in
      completely, including
      telephone number(s).
</TABLE>
 
/ / United States Citizen  / / Resident Alien
                   Street or P.O. Box
                   City
                   State                   Zip
Home Telephone No.                   Business Telephone No.
 
/ / Non-Resident Alien:
 
Permanent Address (Where you reside permanently for tax purposes)
                   Street Address
                   City
                   Country                   Postal Code
Home Telephone No.                    Business Telephone No.
 
Current Mailing Address (If different from Permanent Address)
                   Street Address
                   City
                   Country
Postal Code
Home Telephone No.                   Business Telephone No.
 
<TABLE>
<S>   <S>                        <C>                             <C>
  C)  TAXPAYER                   Enter your Taxpayer Identification Number. For most individual
      IDENTIFICATION             taxpayers, this is your Social Security Number.
      NUMBER
      1. INDIVIDUAL
      2. JOINT TENANTS
         (RIGHTS OF
      SURVIVORSHIP PRESUMED
      UNLESS
         TENANCY IN COMMON
         IS INDICATED)
</TABLE>
<PAGE>
<TABLE>
<S>   <S>                        <C>                             <C>
      For Custodian account
      of a minor (Uniform
      Gifts/Transfers to Minor
      Acts), give the Social
      Security Number of
      the minor
                                                                 OR
                                 1.         TAXPAYER             SOCIAL SECURITY NUMBER
                                 IDENTIFICATION NUMBER           ("SSN")
                                 ("TIN")
                                                                 OR
                                 2.                                                          TIN                                SSN
                                                                 OR
                                                               TIN                                SSN
                                 IMPORTANT TAX INFORMATION
                                 You (as a payee) are required by law to provide us (as  payer)
                                 with  your  correct TIN(s)  or  SSN(s). Accounts  that  have a
                                 missing or  incorrect  TIN(s) or  SSN(s)  will be  subject  to
                                 backup  withholding at a 31%  rate on dividends, distributions
                                 and other  payments. If  you have  not provided  us with  your
                                 correct  TIN(s) or SSN(s), you may be subject to a $50 penalty
                                 imposed by the Internal Revenue Service.
                                 Backup withholding is not an additional tax; the tax liability
                                 of persons subject  to backup withholding  will be reduced  by
                                 the  amount  of tax  withheld.  If withholding  results  in an
                                 overpayment   of   taxes,   a   refund   may   be    obtained.
                                 You may be notified that you are subject to backup withholding
                                 under  Section  3406(a)(1)(C)  of  the  Internal  Revenue Code
                                 because you have  underreported interest or  dividends or  you
                                 were  required to,  but failed to,  file a  return which would
                                 have included a reportable interest or dividend payment.
</TABLE>
 
<PAGE>
 
   
<TABLE>
<C>   <S>                        <C>                             <C>
  D)  PORTFOLIO AND              For Purchase of the following
      CLASS SECTION              Portfolio(s):                   / / Class A Shares
      (Class A shares minimum    Technology Portfolio            $ / / Class B Shares $
      $250,000 for the                                           Total Initial Investment
      Portfolio and Class B                                      $
      shares minimum $50,000
      for the Portfolio).
      Please indicate class and
      amount.
</TABLE>
    
 
<TABLE>
<C>   <S>                        <C>
  E)  METHOD OF
      INVESTMENT
      Please indicate
      portfolio, manner of
      payment.
</TABLE>
 
Payment by:
 
/ / Check (MAKE CHECK PAYABLE TO MORGAN STANLEY INSTITUTIONAL FUND,
INC.--PORTFOLIO NAME)
 
<TABLE>
<S>                                                                                 <C>
/ / Exchange $ From                                                                           -- - - - - - - - - - -- - -
                                                      Name of Portfolio                               Account No.
/ / Account previously established by:  / / Phone exchange  / / Wire on                       -- - - - - - - - - - -- - -
                                                                                            Account No.               (Check
                                                                                      (Previously assigned by the Fund)     Digit)
                                                                            Date
</TABLE>
 
<TABLE>
<C>   <S>                        <C>
  F)  DISTRIBUTION               Income dividends and capital gains distributions (if any) to
      OPTION                     be reinvested in additional shares unless either box below
                                 is checked.
                                 / / Income dividends to be paid in cash, capital gains
                                 distributions (if any) in shares.
                                 / / Income dividends and capital gains distributions (if
                                 any) to be paid in cash.
</TABLE>
 
<TABLE>
<C>   <S>                             <C>                                       <C>
  G)  TELEPHONE                       / / I/we hereby authorize the Fund and
      REDEMPTION                      its agents to honor any telephone         Name of COMMERCIAL Bank (Not Savings
      AND EXCHANGE                    requests to wire redemption proceeds to   Bank)
      OPTION                          the commercial bank indicated at right    Bank Account No.
      Please select at time of        and/or mail redemption proceeds to the
      initial application if you      name and address in which my/our fund
      wish to redeem or exchange      account is registered if such requests                                        Bank
      shares by telephone. A          are believed to be authentic.                                                  ABA
      SIGNATURE GUARANTEE IS          The Fund and the Fund's Transfer Agent                                         No.
      REQUIRED IF BANK ACCOUNT IS     will employ reasonable procedures to
      NOT REGISTERED IDENTICALLY TO   confirm that instructions communicated    Name(s) in which your BANK Account is
      YOUR FUND ACCOUNT.              by telephone are genuine. These           Established
      TELEPHONE REQUESTS FOR          procedures include requiring the
      REDEMPTIONS OR EXCHANGE WILL    investor to provide certain personal      Bank's Street
      NOT BE HONORED UNLESS THE BOX   identification information at the time    Address
      IS CHECKED.                     an account is opened and prior to
                                      effecting each transaction requested by   City        State Zip
                                      telephone. In addition, all telephone
                                      transaction requests will be recorded
                                      and investors may be required to provide
                                      additional telecopied written
                                      instructions of transaction requests.
                                      Neither the Fund nor the Transfer Agent
                                      will be responsible for any loss,
                                      liability, cost or expense for following
                                      instructions received by telephone that
                                      it reasonably believes to be genuine.
</TABLE>
 
   
<TABLE>
<C>   <S>                        <C>
  H)  INTERESTED PARTY
      OPTION                                                                                      Name
      In addition to the
      account statement sent to
      my/our registered                                                                          Address
      address, I/we hereby
      authorize the Fund to        City                                         State                                         Z
      mail duplicate statements  Code
      to the name and address
      provided at right.
</TABLE>
    
 
<TABLE>
<C>   <S>                        <C>
  I)  DEALER
      INFORMATION
                                 Representative Name                        Representative
                                 No.                            Branch
                                 No.
</TABLE>
 
<PAGE>
 
<TABLE>
<C>   <S>                        <C>
  J)  SIGNATURE OF
      ALL HOLDERS
      AND TAXPAYER
      CERTIFICATION
      Sign Here ,
</TABLE>
 
<TABLE>
<S>                                  <C>
The undersigned certify that I/we have full authority and legal capacity
to purchase and redeem shares of the Fund and affirm that I/we have
received a current Prospectus of the Morgan Stanley Institutional Fund,
Inc. and agree to be bound by its terms.
  BY SIGNING THIS  APPLICATION, I/WE HEREBY  CERTIFY UNDER PENALTIES  OF
PERJURY THAT THE INFORMATION ON THIS APPLICATION IS COMPLETE AND CORRECT
AND  THAT  AS REQUIRED  BY FEDERAL  LAW  (PLEASE CHECK  APPLICABLE BOXES
BELOW):
/ / U.S. CITIZEN(S)/TAXPAYER(S):
       / / I/WE CERTIFY THAT (1) THE NUMBER(S) SHOWN ABOVE ON THIS  FORM
           IS/ARE  THE CORRECT  SSN(S) OR  TIN(S) AND  (2) I/WE  ARE NOT
           SUBJECT TO ANY BACKUP WITHHOLDING EITHER BECAUSE (A) I/WE ARE
           EXEMPT FROM  BACKUP  WITHHOLDING;  (B)  I/WE  HAVE  NOT  BEEN
           NOTIFIED  BY THE  INTERNAL REVENUE SERVICE  ("IRS") THAT I/WE
           ARE SUBJECT TO BACKUP WITHHOLDING AS A RESULT OF A FAILURE TO
           REPORT ALL INTEREST OR DIVIDENDS; OR (C) THE IRS HAS NOTIFIED
           ME/US  THAT  I  AM/WE  ARE   NO  LONGER  SUBJECT  TO   BACKUP
           WITHHOLDING.
       /  / IF  NO TIN(S) OR  SSN(S) HAS/HAVE BEEN  PROVIDED ABOVE, I/WE
           HAVE APPLIED, OR INTEND  TO APPLY, TO THE  IRS OR THE  SOCIAL
           SECURITY   ADMINISTRATION  FOR  A  TIN  OR  A  SSN  AND  I/WE
           UNDERSTAND THAT IF I/WE DO NOT PROVIDE EITHER NUMBER TO CHASE
           GLOBAL FUNDS SERVICES COMPANY ("CGFSC") WITHIN 60 DAYS OF THE
           DATE OF THIS APPLICATION  OR IF I/WE  FAIL TO FURNISH  MY/OUR
           CORRECT  SSN(S) OR TIN(S),  I/WE MAY BE  SUBJECT TO A PENALTY
           AND A 31% BACKUP WITHHOLDING ON DISTRIBUTIONS AND  REDEMPTION
           PROCEEDS. (PLEASE PROVIDE EITHER NUMBER ON IRS FORM W-9). YOU
           MAY REQUEST SUCH FORM BY CALLING CGFSC AT 800-282-4404.
 
/ / NON-U.S. CITIZEN(S)/TAXPAYER(S)
  UNDER  PENALTIES  OF  PERJURY, I/WE  CERTIFY  THAT I/WE  ARE  NOT U.S.
CITIZENS OR RESIDENTS AND I/WE ARE EXEMPT FOREIGN PERSONS AS DEFINED  BY
THE INTERNAL REVENUE SERVICE.
 
THE  INTERNAL  REVENUE  SERVICE DOES  NOT  REQUIRE YOUR  CONSENT  TO ANY
PROVISION OF THIS  DOCUMENT OTHER  THAN THE  CERTIFICATIONS REQUIRED  TO
AVOID BACKUP WITHHOLDING.
 
                                     (X)
(X)                                  Signature (if joint account, both
Signature                                                                     Date must sign)         Date
</TABLE>
<PAGE>

                     MORGAN STANLEY INSTITUTIONAL FUND, INC.
                       STATEMENT OF ADDITIONAL INFORMATION

   
     Morgan Stanley Institutional Fund, Inc. (the "Fund") is a no-load, 
open-end management investment company with diversified and non-diversified 
series ("Portfolios").  The Fund currently consists of twenty-nine Portfolios 
offering a broad range of investment choices.  The Fund is designed to 
provide clients with attractive alternatives for meeting their investment 
needs.  Each Portfolio, except the Money Market, Municipal Money Market, 
International Small Cap and China Growth Portfolios, offers two classes of 
shares, the Class A shares and the Class B shares (each, a "Multiclass 
Portfolio").  The Class A shares and the Class B shares currently offered by 
each Multiclass Portfolio have different minimum investment requirements and 
fund expenses.  Shares of each Portfolio are offered with no sales charge or 
exchange or redemption fee (except that the International Small Cap Portfolio 
may impose a transaction fee).  This Statement of Additional Information 
addresses information of the Fund applicable to all of the Fund's Portfolios, 
except the Technology Portfolio.
    
     This Statement is not a prospectus but should be read in conjunction with
the several prospectuses of the Fund's Portfolios (the "Prospectuses").  To
obtain any of the Prospectuses, please call the Morgan Stanley Institutional
Fund, Inc. Services Group at 1-800-548-7786.

                                TABLE OF CONTENTS

                                                                            PAGE
                                                                            ----
Investment Objectives and Policies . . . . . . . . . . . . . . . . . . . .     2
Taxes  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .    25
General Regulated Investment Company Qualifications  . . . . . . . . . . .    25
General Tax Treatment of Qualifying RICs and Shareholders. . . . . . . . .    26
Special Tax Considerations Relating to Municipal Bond and
  Municipal Money Market Portfolios  . . . . . . . . . . . . . . . . . . .    28
Special Tax Considerations Relating to Foreign Investments . . . . . . . .    30
Taxes and Foreign Shareholders . . . . . . . . . . . . . . . . . . . . . .    30
Purchase of Shares . . . . . . . . . . . . . . . . . . . . . . . . . . . .    31
Redemption of Shares . . . . . . . . . . . . . . . . . . . . . . . . . . .    31
Shareholder Services . . . . . . . . . . . . . . . . . . . . . . . . . . .    32
Investment Limitations . . . . . . . . . . . . . . . . . . . . . . . . . .    33
Determining Maturities of Certain Instruments. . . . . . . . . . . . . . .    35
Management of the Fund . . . . . . . . . . . . . . . . . . . . . . . . . .    35
Net Asset Value for Money Market Portfolios. . . . . . . . . . . . . . . .    51
Performance Information. . . . . . . . . . . . . . . . . . . . . . . . . .    51
General Information. . . . . . . . . . . . . . . . . . . . . . . . . . . .    59
Description of Ratings . . . . . . . . . . . . . . . . . . . . . . . . . .    61
Financial Statements . . . . . . . . . . . . . . . . . . . . . . . . . . .    63

   
STATEMENT OF ADDITIONAL INFORMATION DATED MAY 1, 1997
    
     Prospectus for the International Magnum Portfolio, dated May 1, 1997

     Prospectus for the U.S. Real Estate Portfolio, dated May 1, 1997

     Prospectus for the Fixed Income Portfolio, Municipal Bond Portfolio, 
     Mortgage-Backed Securities Portfolio, Money Market Portfolio and 
     Municipal Money Market Portfolio, dated May 1, 1997

     Prospectus for the Equity Growth Portfolio, Emerging Growth Portfolio,
     MicroCap Portfolio and Aggressive Equity Portfolio, dated May 1, 1997

     Prospectus for the Small Cap Value Equity Portfolio, Value Equity 
     Portfolio, Balanced Portfolio, Global Fixed Income Portfolio and High 
     Yield Portfolio, dated May 1, 1997

     Prospectus for the Global Equity Portfolio, International Equity Portfolio,
     International Small Cap Portfolio, Asian Equity Portfolio, European Equity
     Portfolio, Japanese Equity Portfolio and Latin American Portfolio, dated
     May 1, 1997

     Prospectus for the Emerging Markets Portfolio and Emerging Markets Debt
     Portfolio, dated May 1, 1997

     Prospectus for the Active Country Allocation Portfolio, dated May 1, 1997

     Prospectus for the Gold Portfolio, dated May 1, 1997

     Prospectus for the China Growth Portfolio, dated May 1, 1995.
<PAGE> 

                       INVESTMENT OBJECTIVES AND POLICIES

     The following policies supplement the investment objectives and policies
set forth in the Fund's Prospectuses:

BRADY BONDS.

     The Emerging Markets Debt Portfolio may invest in certain debt
obligations customarily referred to as "Brady Bonds," which are created
through the exchange of existing commercial bank loans to foreign entities
for new obligations in connection with debt restructuring under a plan
introduced by former U.S. Secretary of the Treasury Nicholas F. Brady (the
"Brady Plan"). Brady Bonds have been issued only recently and, accordingly,
do not have a long payment history.  They may be collateralized or
uncollateralized and issued in various currencies (although most are U.S.
dollar-denominated) and they are actively traded in the over-the-counter
secondary market.  The Portfolio may purchase Brady Bonds either in the
primary or secondary markets.  The price and yield of Brady Bonds purchased
in the secondary market will reflect the market conditions at the time of
purchase, regardless of the stated face amount and the stated interest rate.
With respect to Brady Bonds with no or limited collateralization, the
Portfolio will rely for payment of interest and principal primarily on the
willingness and ability of the issuing government to make payment in
accordance with the terms of the bonds.

     U.S. dollar-denominated, collateralized Brady Bonds, which may be fixed
rate par bonds or floating rate discount bonds, are generally collateralized in
full as to principal due at maturity by U.S. Treasury zero coupon obligations
which have the same maturity as the Brady Bonds.  Interest payments on these
Brady Bonds generally are collateralized by cash or securities in an amount
that, in the case of fixed rate bonds, is equal to at least one year of rolling
interest payments or, in the case of floating rate bonds, initially is equal to
at least one year's rolling interest payments based on the applicable interest
rate at that time and is adjusted at regular intervals thereafter.  Certain
Brady Bonds are entitled to "value recovery payments" in certain circumstances,
which in effect constitute supplemental interest payments but generally are not
collateralized.  Brady Bonds are often viewed as having three or four valuation
components: (i) the collateralized repayment of principal at final maturity;
(ii) the collateralized interest payments; (iii) the uncollateralized interest
payments; and (iv) any uncollateralized repayment of principal at maturity
(these uncollateralized amounts constitute the "residual risk").  In the event
of a default with respect to collateralized Brady Bonds as a result of which the
payment obligations of the issuer are accelerated, the U.S. Treasury zero coupon
obligations held as collateral for the payment of principal will not be
distributed to investors, nor will such obligations be sold and the proceeds
distributed.  The collateral will be held to the scheduled maturity of the
defaulted Brady Bonds by the collateral agent, at which time the face amount of
the collateral will equal the principal payments which would have then been due
on the Brady Bonds in the normal course.  In addition, in light of the residual
risk of the Brady Bonds and, among other factors, the history of defaults with
respect to commercial bank loans by public and private entities of countries
issuing Brady Bonds, investments in Brady Bonds should be viewed as speculative.

     Brady Plan debt restructuring totalling approximately $73 billion have been
implemented to date in Argentina, Bulgaria, Costa Rica, Ecuador, Mexico,
Nigeria, the Philippines, Uruguay and Venezuela, with the largest proportion of
Brady Bonds having been issued to date by Mexico and Venezuela.  Brazil and
Poland have announced plans to issue Brady Bonds aggregating approximately $52
billion, based on current estimates.  There can be no assurance that the
circumstances regarding the issuance of Brady Bonds by these countries will not
change.



                                        2
<PAGE> 

CURRENCY SWAPS 
   
The China Growth Portfolio may enter into currency swaps for hedging purposes 
and non-hedging purposes.  Inasmuch as swaps are entered into for good faith 
hedging purposes and are offset by a segregated account as described below, 
the Portfolio believes that swaps do not constitute senior securities as 
defined in the Investment Company Act of 1940 (the "1940 Act") and, 
accordingly, will not treat them as being subject to the Portfolio's 
borrowing restrictions.  An amount of cash or liquid securities having an 
aggregate net asset value at least equal to the gross payments which the 
Portfolio is obligated to make under the currency swap will be maintained in 
a segregated account by the Fund's Custodian.  The Portfolio will not enter 
into any currency swap unless the credit quality of the unsecured senior debt 
or the claims-paying ability of the other party thereto is considered to be 
investment grade by Morgan Stanley Asset Management Inc. ("MSAM" or the 
"Adviser"). If there is a default by the other party to such a transaction, 
the Portfolio will have contractual remedies pursuant to the agreements 
related to the transaction.  The swap market has grown substantially in 
recent years with a large number of banks and investment banking firms acting 
both as principals and as agents utilizing standardized swap documentation.  
As a result, the swap market has become relatively liquid in comparison with 
the markets for other similar instruments which are traded in the interbank 
market. 
    

EMERGING COUNTRY EQUITY AND DEBT SECURITIES
   
GENERAL.  Each of the Active Country Allocation, Latin American, 
International Magnum, Active Country Allocation, Global Equity, International 
Equity, International Small Cap, Asian Equity, European Equity, Emerging 
Markets and Emerging Markets Debt Portfolios' definition of emerging country 
equity or debt securities includes securities of companies that may have 
characteristics and business relationships common to companies in a country 
or countries other than an emerging country. As a result, the value of the 
securities of such companies may reflect economic and market forces 
applicable to other countries, as well as to an emerging country.  The 
Adviser believes, however, that investment in such companies will be 
appropriate because the Portfolio will invest only in those companies which, 
in its view, have sufficiently strong exposure to economic and market forces 
in an emerging country that their value will tend to reflect developments in 
such emerging country to a greater extent than developments in another 
country or countries.  For example, the Portfolio may invest in companies 
organized and located in countries other than an emerging country, including 
companies having their entire production facilities outside of an emerging 
country, when securities of such companies meet one or more elements of the 
Portfolio's definition of an emerging country equity or debt security and so 
long as the Adviser believes at the time of investment that the value of the 
company's securities principally reflects conditions in such emerging country.
    
     The Emerging Markets Debt Portfolio is subject to no restrictions on the
maturities of the emerging country debt securities it holds; those maturities
may range from overnight to 30 years.  The value of debt securities held by the
Portfolio generally will vary inversely to changes in prevailing interest rates.
The Portfolio's investments in fixed-rated debt securities with longer terms to
maturity are subject to greater volatility than the Portfolio's investments in
shorter-term obligations.  Debt obligations acquired at a discount are subject
to greater fluctuations of market value in response to changing interest rates
than debt obligations of comparable maturities which are not subject to such
discount.


                                        3
<PAGE> 


     Investments in emerging country government debt securities involve
special risks.  Certain emerging countries have historically experienced, and
may continue to experience, high rates of inflation, high interest rates,
exchange rate fluctuations, large amounts of external debt, balance of
payments and trade difficulties and extreme poverty and unemployment. The
issuer or governmental authority that controls the repayment of an emerging
country's debt may be unable or unwilling to repay the principal and/or
interest when due in accordance with the terms of such debt.  As a result of
the foregoing, a government obligor may default on its obligations.  If such
an event occurs, the Portfolio may have limited legal recourse against the
issuer and/or guarantor.  Remedies must, in some cases, be pursued in the
courts of the defaulting party itself, and the ability of the holder of
foreign government debt securities to obtain recourse may be subject to the
political climate in the relevant country.   In addition, no assurance can be
given that the holders of commercial bank debt will not contest payments to
the holders of other foreign government debt obligations in the event of
default under their commercial bank loan agreements.

EQUITY-LINKED SECURITIES

     The Aggressive Equity Portfolio may invest in equity-linked securities, 
including, among others, PERCS, ELKS or LYONs, which are securities that are 
convertible into or the value of which is based upon the value of, equity 
securities upon certain terms and conditions. The amount received by an 
investor at maturity of such securities is not fixed but is based on the 
price of the underlying common stock. It is impossible to predict whether the 
price of the underlying common stock will rise or fall. Trading prices of the 
underlying common stock will be influenced by the issuer's operational 
results, by complex, interrelated political, economic, financial, or other 
factors affecting the capital markets, the stock exchanges on which the 
underlying common stock is traded and the market segment of which the issuer 
is a part. In addition, it is not possible to predict how equity-linked 
securities will trade in the secondary market, which is fairly developed and 
liquid. The market for such securities may be shallow, however, and high 
volume trades may be possible only with discounting. In addition to the 
foregoing risks, the return on such securities depends on the 
creditworthiness of the issuer of the securities, which may be the issuer of 
the underlying securities or a third party investment banker or other lender. 
The creditworthiness of such third party issuer of equity-linked securities 
may, and often does, exceed the creditworthiness of the issuer of the 
underlying securities. The advantage of using equity-linked securities over 
traditional equity and debt securities is that the former are income 
producing vehicles that may provide a higher income than the dividend income 
on the underlying equity securities while allowing some participation in the 
capital appreciation of the underlying equity securities. Another advantage 
of using equity-linked securities is that they may be used for hedging to 
reduce the risk of investing in the generally more volatile underlying equity 
securities.

     The following are three examples of equity-linked securities. The 
Portfolio may invest in the securities described below or other similar 
equity-linked securities.

     PERCS.  Preferred Equity Redemption Cumulative Stock ("PERCS") 
technically is preferred stock with some characteristics of common stock. 
PERCS are mandatorily convertible into common stock after a period of time, 
usually three years, during which the investors' capital gains are capped, 
usually at 30%. Commonly, PERCS may be redeemed by the issuer at any time or 
if the issuer's common stock is trading at a specified price level or better.
The  redemption price starts at the beginning of the PERCS duration period at
a price that is above the cap by the amount of the extra dividends the PERCS 
holder is entitled to receive relative to the common stock over the duration 
of the PERCS and declines to the cap price shortly before maturity of the 
PERCS. In exchange for having the cap on capital gains and giving the issuer 
the option to redeem the PERCS at any time or at the specified common stock 
price level, the Portfolio may be compensated with a substantially higher 
dividend yield than that on the underlying common stock. Investors, such as 
the Portfolio, that seek current income find PERCS attractive because 
PERCS provide a higher dividend income than that paid with respect to a 
company's common stock.

     ELKS.  Equity-Linked Securities ("ELKS") differ from ordinary debt 
securities, in that the principal amount received at maturity is not fixed 
but is based on the price of the issuer's common stock. ELKS are debt 
securities commonly issued in fully registered form for a term of three years 
under an indenture trust. At maturity, the holder of ELKS will be entitled to 
receive a principal amount equal to the lesser of a cap amount, commonly in 
the range of 30% to 55% greater than the current price of the issuer's common 
stock, or the average closing price per share of the issuer's common stock, 
subject to adjustment as a result of certain dilution events, for the 10 
trading days immediately prior to maturity. Unlike PERCS, ELKS are commonly 
not subject to redemption prior to maturity. ELKS usually bear interest 
during the three-year term at a substantially higher rate than the dividend 
yield on the underlying common stock. In exchange for having the cap on the 
return that might have been received as capital gains on the underlying 
common stock, the Portfolio may be compensated with the higher yield, 
contingent on how well the underlying common stock does. Investors, such as 
the Portfolio, that seek current income, find ELKS attractive because ELKS 
provide a higher dividend income than that paid with respect to a company's 
common stock.

     LYONs.  Liquid Yield Option Notes ("LYONs") differ from ordinary debt 
securities, in that the amount received prior to maturity is not fixed but is 
based on the price of the issuer's common stock. LYONs are zero-coupon notes 
that sell at a large discount from face value. For an investment in LYONs, 
the Portfolio will not receive any interest payments until the notes mature, 
typically in 15 to 20 years, when the notes are redeemed at face, or par, 
value. The yield on LYONs, typically, is lower-than-market rate for debt 
securities of the same maturity, due in part to the fact that the LYONs are 
convertible into common stock of the issuer at any time at the option of the 
holder of the LYONs. Commonly, the LYONs are redeemable by the issuer at any 
time after an initial period or if the issuer's common stock is trading at a 
specified price level or better or, at the option of the holder, upon 
certain fixed dates. The redemption price typically is the purchase price of 
the LYONs plus accrued original issue discount to the date of redemption, 
which amounts to the lower-than-market yield. The Portfolio will receive only 
the lower-than-market yield unless the underlying common stock increases in 
value at a substantial rate. LYONs are attractive to investors like the 
Portfolio when it appears that they will increase in value due to the rise 
in value of the underlying common stock.


                                        4
<PAGE> 


FOREIGN CURRENCY FORWARD CONTRACTS

     The U.S. dollar value of the assets of the Global Equity, International
Equity, International Small Cap, Asian Equity, European Equity, Japanese Equity,
Latin American, International Magnum, Global Fixed Income, Active Country
Allocation, China Growth, Emerging Markets, Emerging Markets Debt and Gold
Portfolios and, to the extent they invest in securities denominated in foreign
currencies, the assets of the Equity Growth, Emerging Growth, MicroCap, 
Aggressive Equity, Small Cap Value Equity, Value Equity, Balanced, Fixed Income 
and High Yield Portfolios may be affected favorably or unfavorably by changes in
foreign currency exchange rates and exchange control regulations, and the 
Portfolios may incur costs in connection with conversions between various 
currencies.  The Portfolios will conduct their foreign currency exchange 
transactions either on a spot (i.e., cash) basis at the spot rate prevailing in
the foreign currency exchange market, or through entering into forward contracts
to purchase or sell foreign currencies.  A foreign currency forward contract 
involves an obligation to purchase or sell a specific currency at a future date,
which may be any fixed number of days from the date of the contract agreed upon 
by the parties, at a price set at the time of the contract.  These contracts are
traded in the interbank market conducted directly between currency traders 
(usually large commercial banks) and their customers.  A forward contract 
generally has no deposit requirement, and no commissions are charged at any 
stage for such trades.  The Gold Portfolio may also enter into precious metals 
forward contracts.  See "Precious Metals Forward and Futures Contracts and 
Options on Futures Contracts" below.

     The Portfolios may enter into foreign currency forward contracts in
several circumstances.  When a Portfolio enters into a contract for the
purchase or sale of a security denominated in a foreign currency, or when a
Portfolio anticipates the receipt in a foreign currency of dividends or
interest payments on a security which it holds, the Portfolio may desire to
"lock-in" the U.S. dollar price of the security or the U.S. dollar equivalent
of such dividend or interest payment, as the case may be.  By entering into a
forward contract for a fixed amount of dollars, for the purchase or sale of
the amount of foreign currency involved in the underlying transactions, the
Portfolio will be able to protect itself against a possible loss resulting
from an adverse change in the relationship between the U.S. dollar and the
subject foreign currency during the period between the date on which the
security is purchased or sold, or on which the dividend or interest payment
is declared, and the date on which such payments are made or received.

     Additionally, when any of these Portfolios anticipates that the currency of
a particular foreign country may suffer a substantial decline against the U.S.
dollar, it may enter into a forward contract for a fixed amount of dollars, to
sell the amount of foreign currency approximating the value of some or all of
such Portfolio's securities denominated in such foreign currency.  The precise
matching of the forward contract amounts and the value of the securities
involved will not generally be possible since the future value of securities in
foreign currencies will change as a consequence of market movements in the value
of these securities between the date on which the forward contract is entered
into and the date it matures.  The projection of short-term currency market
movement is extremely difficult, and the successful execution of a short-term
hedging strategy is highly uncertain. None of the Portfolios intend to enter
into such forward contracts to protect the value of portfolio securities on a
continuous basis.  The Portfolios will not enter into such forward contracts or
maintain a net exposure to such contracts where the consummation of the
contracts would obligate such Portfolio to deliver an amount of foreign
currency in excess of the value of such Portfolio's securities or other assets
denominated in that currency.


                                        5
<PAGE> 

     Under normal circumstances, consideration of the prospect for currency 
parities will be incorporated into the long-term investment decisions made 
with regard to overall diversification strategies.  However, the management 
of the Fund believes that it is important to have the flexibility to enter 
into such forward contracts when it determines that the best interests of the 
performance of each Portfolio will thereby be served.  Except under 
circumstances where a segregated account is not required under the 1940 Act 
or the rules adopted thereunder, the Fund's Custodian will place cash or 
liquid  securities into a segregated account of a Portfolio in an amount 
equal to the value of such Portfolio's total assets committed to the 
consummation of forward currency exchange contracts. If the value of the 
securities placed in the segregated account declines, additional cash or 
securities will be placed in the account on a daily basis so that the value 
of the account will be equal to the amount of such Portfolio's commitments 
with respect to such contracts.

     The Portfolios generally will not enter into a forward contract with a term
of greater than one year.  At the maturity of a forward contract, a Portfolio
may either sell the portfolio security and make delivery of the foreign
currency, or it may retain the security and terminate its contractual obligation
to deliver the foreign currency by purchasing an "offsetting" contract with the
same currency trader obligating it to purchase, on the same maturity date, the
same amount of the foreign currency.

     It is impossible to forecast with absolute precision the market value of a
particular portfolio security at the expiration of the contract.  Accordingly,
it may be necessary for a Portfolio to purchase additional foreign currency on
the spot market (and bear the expense of such purchase) if the market value of
the security is less than the amount of foreign currency that such Portfolio is
obligated to deliver and if a decision is made to sell the security and make
delivery of the foreign currency.

     If a Portfolio retains the portfolio security and engages in an offsetting
transaction, such Portfolio will incur a gain or a loss (as described below) to
the extent that there has been movement in forward contract prices.  Should
forward prices decline during the period between a Portfolio entering into a
forward contract for the sale of a foreign currency and the date it enters into
an offsetting contract for the purchase of the foreign currency, such Portfolio
will realize a gain to the extent that the price of the currency it has agreed
to sell exceeds the price of the currency it has agreed to purchase.  Should
forward prices increase, such Portfolio would suffer a loss to the extent that
the price of the currency it has agreed to purchase exceeds the price of the
currency it has agreed to sell.

     The Portfolios are not required to enter into such transactions with regard
to their foreign currency-denominated securities.  It also should be realized
that this method of protecting the value of portfolio securities against a
decline in the value of a currency does not eliminate fluctuations in the
underlying prices of the securities.  It simply establishes a rate of exchange
which one can achieve at some future point in time.  Additionally, although such
contracts tend to minimize the risk of loss due to a decline in the value of the
hedged currency, at the same time, they tend to limit any potential gain which
might result should the value of such currency increase.  For a discussion of
the special risks associated with foreign currency transactions, see "Risks
Associated with Foreign Currency Transactions," below in this SAI.


                                        6
<PAGE> 


RISKS ASSOCIATED WITH FOREIGN CURRENCY TRANSACTIONS

     Transactions in foreign currency forward contracts, foreign currency
futures contracts and options thereon, and options on foreign currencies, are
subject to the risk of governmental actions affecting trading in or the
prices of currencies underlying such contracts, which could restrict or
eliminate trading and could have a substantial adverse effect on the value of
positions held by the Portfolios permitted to engage in such hedging
transactions.  In addition, the value of such positions could be adversely
affected by a number of other complex political and economic factors
applicable to the countries issuing the underlying currencies.

     Furthermore, unlike trading in most other types of instruments, there is no
systematic reporting of last sale information with respect to the foreign
currencies underlying forward contracts, futures contracts and options.  As a
result, the available information on which a Portfolio's trading systems will be
based may not be as complete as the comparable data on which such Portfolio
makes investment and trading decisions in connection with securities and other
transactions.  Moreover, because the foreign currency market is a global,
twenty-four hour market, events could occur on that market which will not be
reflected in the forward, futures or options markets until the following day,
thereby preventing a Portfolio from responding to such events in a timely
manner.
   
     Settlement of over-the-counter ("OTC") forward contracts or the exercise 
of foreign currency options generally must occur within the country issuing 
the underlying currency, which in turn requires parties to such contracts to 
accept or make delivery of such currencies in conformity with any United 
States or foreign restrictions and regulations regarding the maintenance of 
foreign banking relationships, fees, taxes or other charges.

     Unlike currency futures contracts and exchange-traded options, OTC 
options on foreign currencies and foreign currency forward contracts are not 
traded on contract markets or national securities exchanges regulated by the 
Commodity Futures Trading Commission ("CFTC") or the Securities and Exchange 
Commission (the "Commission"), respectively.  In an OTC trading environment, 
many of the protections associated with transactions on exchanges will not be 
available.
    
     For example, there are no daily price fluctuation limits, and adverse
market movements could therefore continue to an unlimited extent over a
period of time. Although the purchaser of an option cannot lose more than the
amount of the premium plus related transaction costs, this entire amount
could be lost. Moreover, an option writer could lose amounts substantially in
excess of its initial investment due to the margin and collateral
requirements associated with such option positions.  Similarly, there is no
limit on the amount of potential losses on forward contracts to which a
Portfolio is a party.

     In addition, OTC transactions can only be entered into with a financial
institution willing to take the opposite side, as principal, of a Portfolio's
position unless the institution acts as broker and is able to find another
counterparty willing to enter into the transaction with such Portfolio. Where
no such counterparty is available, it will not be possible to enter into a
desired transaction.  There also may be no liquid secondary market in the
trading of OTC contracts, and a Portfolio may be unable to close out options
purchased or written, or forward contracts entered into, until their
exercise, expiration or maturity.  This in turn could limit a Portfolio's
ability to realize profits or to reduce losses on open positions and could
result in greater losses.


                                        7
<PAGE> 

     Furthermore, OTC transactions are not backed by the guarantee of an
exchange's clearing corporation.  A Portfolio will therefore be subject to
the risk of default by, or the bankruptcy of, the financial institution
serving as its counterparty.  One or more of such institutions also may
decide to discontinue its role as market-maker in a particular currency,
thereby restricting a Portfolio's ability to enter into desired hedging
transactions.  A Portfolio will enter into OTC transactions only with parties
whose creditworthiness has been reviewed and found satisfactory by the
Adviser.
   
     OTC options on foreign currencies are within the exclusive regulatory 
jurisdiction of the CFTC.  The CFTC currently permits the trading of such 
options, but only subject to a number of conditions regarding the commercial 
purpose of the purchaser of such options.  The Portfolios are not able to 
determine at this time whether or to what extent the CFTC may impose 
additional restrictions on the trading of over-the-counter options on foreign 
currencies at some point in the future, or the effect that any restrictions 
may have on the hedging strategies to be implemented by the Portfolios.  
Forward contracts and currency swaps are not presently subject to regulation 
by the CFTC, although the CFTC may in the future assert or be granted 
authority to regulate such instruments.  In such event, a Portfolio's ability 
to utilize forward contracts and currency swaps in the manner set forth above 
and in the applicable Prospectus could be restricted.
    
     Options on foreign currencies traded on a national securities exchange
are within the jurisdiction of the Commission, as are other securities traded
on such exchanges.  As a result, many of the protections provided to traders
on organized exchanges will be available with respect to such transactions.
In particular, all foreign currency options positions entered into on a
national securities exchange are cleared and guaranteed by the Options
Clearing Corporation ("OCC"), thereby reducing the risk of counterparty
default. Further, a liquid secondary market in options traded on a national
securities exchange may be more readily available than in the OTC market,
potentially permitting a Portfolio to liquidate open positions at a profit
prior to exercise or expiration, or to limit losses in the event of adverse
market movements.

     The purchase and sale of exchange-traded foreign currency options, however,
is subject to the risks of the availability of a liquid secondary market
described above, as well as the risks regarding adverse market movements,
margining of options written, the nature of the foreign currency market,
possible intervention by governmental authorities and the effect of other
political and economic events.  In addition, exchange-traded options on foreign
currencies involve certain risks not presented by the over-the-counter market.
For example, exercise and settlement of such options must be made exclusively
through the OCC, which has established banking relationships in applicable
foreign countries for this purpose.  As a result, the OCC may, if it determines
that foreign governmental restrictions or taxes would prevent the orderly
settlement of foreign currency option exercises, or would result in undue
burdens on the OCC or its clearing member, impose special procedures for
exercise and settlement, such as technical changes in the mechanics of delivery
of currency, the fixing of dollar settlement prices or prohibitions on exercise.


                                        8
<PAGE> 


FOREIGN INVESTMENTS
   
     The Active Country Allocation, International Equity, International Fixed 
Income, Global Equity, Global Fixed Income, Asian Equity, European Equity, 
Japanese Equity, International Small Cap, Latin American and China Growth 
Portfolios will invest, and the Emerging Growth, Emerging Markets, Emerging 
Markets Debt, Value Equity, Equity Growth, MicroCap, Balanced, Small Cap 
Value Equity, International Magnum, Fixed Income, High Yield, Aggressive 
Equity and Gold Portfolios may invest in securities of foreign issuers.  
Investors should recognize that investing in such foreign securities involves 
certain special considerations which are not typically associated with 
investing in U.S. issuers. For a description of the effect on the Portfolios 
of currency exchange rate fluctuation, see "Foreign Currency Forward Contracts"
above. As foreign issuers are not generally subject to uniform accounting,
auditing and financial reporting standards and may have policies that are not 
comparable to those of domestic issuers, there may be less information 
available about certain foreign companies than about domestic issuers.  
Securities of some foreign issuers are generally less liquid and more 
volatile than securities of comparable domestic issuers.  There is generally 
less government supervision and regulation of stock exchanges, brokers and 
listed issuers than in the United States. In addition, with respect to certain 
foreign countries, there is the possibility of expropriation or confiscatory 
taxation, political or social instability, or diplomatic developments which 
could affect U.S. investments in those countries.  Foreign securities not 
listed on a recognized domestic or foreign exchange are regarded as not 
readily marketable and therefore such investments will be limited to 15% of a 
Portfolio's net asset value at the time of purchase.
    
     Although the Portfolios will endeavor to achieve the most favorable
execution costs in their portfolio transactions, fixed commissions on many
foreign stock exchanges are generally higher than negotiated commissions on U.S.
exchanges.

     Certain foreign governments levy withholding or other taxes on dividend
and interest income.  Although in some countries a portion of these taxes are
recoverable, the non-recovered portion of foreign withholding taxes will reduce
the income received from investments in such countries.  Except in the case of
the International Equity, Global Equity, European Equity, Japanese Equity, Asian
Equity, Global Fixed Income, International Fixed Income, International Magnum,
International Small Cap, Latin American and China Growth Portfolios, it is not
expected that a Portfolio or its shareholders would be able to claim a credit
for U.S. tax purposes with respect to any such foreign taxes.  However, these
foreign withholding taxes may not have a significant impact on such Portfolios,
because each Portfolio's investment objective is to seek long-term capital
appreciation and any dividend or interest income should be considered
incidental.

FUTURES CONTRACTS 
   
     The Equity Growth, Aggressive Equity, Value Equity, Balanced, Small Cap 
Value Equity, Active Country Allocation, Gold, Latin American, U.S. Real 
Estate, Emerging Markets, Emerging Markets Debt, International Magnum, Fixed 
Income and China Growth Portfolios may enter into futures contracts and 
options on futures contracts for the purpose of remaining fully invested and 
reducing transaction costs.  The Fixed Income, Municipal Bond, 
Mortgage-Backed Securities, High Yield, Active Country Allocation, Municipal 
Bond, Mortgage-Backed Securities, Global Fixed Income, Equity Growth, 
Aggressive Equity, Gold, Latin American, U.S. Real Estate, 
Emerging Markets, Emerging Markets Debt, International Magnum and China 
Growth Portfolios may also enter into futures contracts for hedging purposes. 
 No Portfolio will enter into futures contracts or options thereon for 
speculative purposes.  The Gold Portfolio may also enter into futures 
contracts and options thereon on precious metals.  See "Precious Metals 
Forward and Futures Contracts and Options" below.  Futures contracts provide 
for the future sale by one party and purchase by another party of a specified 
amount of a specific security at a specified future time and at a specified 
price. Futures contracts, which are standardized as to maturity date and 
underlying financial instrument, are traded on national futures exchanges. 
Futures exchanges and trading are regulated under the Commodity Exchange Act 
by the CFTC. 
    

     Although futures contracts by their terms call for actual delivery or 
acceptance of the underlying securities or currencies, in most cases the 
contracts are closed out before the settlement date without the making or 
taking of delivery.  Closing out an open futures position is done by taking 
an opposite position ("buying" a contract which has previously been "sold" or 
"selling" a contract previously "purchased") in an identical contract to 
terminate the position.  Brokerage commissions are incurred when a futures 
contract is bought or sold.

     Futures contracts on securities indices or other indices do not require 
the physical delivery of securities, but merely provide for profits and 
losses resulting from changes in the market value of a contract to be 
credited or debited at the close of each trading day to the respective 
accounts of the parties to the contract.  On the contract's expiration date a 
final cash settlement occurs and the futures position is simply closed out. 
Changes in the market value of a particular futures contract reflect changes 
in the level of the index on which the futures contract is based.

     Futures traders are required to make a good faith margin deposit in cash 
or government securities with a broker or custodian to initiate and maintain 
open positions in futures contracts.  A margin deposit is intended to assure 
completion of the contract (delivery or acceptance of the underlying 
security) if it is not terminated prior to the specified delivery date.  
Minimal initial margin requirements are established by the futures exchange 
and may be changed. Brokers may establish deposit requirements which are 
higher than the exchange minimums.  Futures contracts are customarily 
purchased and sold for prices that may range upward from less than 5% of the 
value of the contract being traded.

     After a futures contract position is opened, the value of the contract 
is marked to market daily.  If the futures contract price changes to the 
extent that the margin on deposit does not satisfy margin requirements, 
payment of an additional "variation" margin will be required.  Conversely, a 
change in the contract value may reduce the required margin, resulting in a 
repayment of excess margin to the contract holder.  Variation margin payments 
are made to and from the futures broker for as long as the contract remains 
open.  The Portfolios expect to earn interest income on their margin 
deposits.  With respect to each long position in a futures contract or option 
thereon, the underlying commodity value of such contract will always be 
covered by cash and cash equivalents set aside plus accrued profits held at 
the futures commission merchant.

                                        9
<PAGE> 

     The Portfolios may purchase and write call and put options on futures 
contracts which are traded on a U.S. Exchange (and in the case of the Active 
Country Allocation, Emerging Markets, Emerging Markets Debt, International 
Magnum, U.S. Real Estate, China Growth and Latin American Portfolios, on any 
recognized securities or futures exchange to the extent permitted by the 
CFTC) and enter into closing transactions with respect to such options to 
terminate an existing position.  An option on a futures contract gives the 
purchaser the right (in return for the premium paid) to assume a position in 
a futures contract (a long position if the option is a call and a short 
position if the option is a put) at a specified exercise price at any time 
during the term of the option.  Upon exercise of the option, the delivery of 
the accumulated balance in the writer's futures margin account, which 
represents the amount by which the market price of the futures contract at 
the time of exercise exceeds, in the case of a call, or is less than, in the 
case of a put, the exercise price of the option on the futures contract.

     The Portfolios will purchase and write options on futures contracts for
identical purposes to those set forth above for the purchase of a futures
contract (purchase of a call option or sale of a put option) and the sale of a
futures contract (purchase of a put option or sale of a call option), or to
close out a long or short position in futures contracts.

     Traders in futures contracts may be broadly classified as either "hedgers"
or "speculators."  Hedgers use the futures markets primarily to offset
unfavorable changes in the value of securities otherwise held for investment
purposes or expected to be acquired by them.  Speculators are less inclined to
own the underlying securities with futures contracts which they trade, and use
futures contracts with the expectation of realizing profits from market
fluctuations.  The Portfolios intend to use futures contracts only for hedging
purposes.

     Regulations of the CFTC applicable to the Portfolios require that all
futures transactions constitute bona fide hedging transactions except that a
Portfolio may engage in futures transactions that do not constitute bona fide
hedging to the extent that not more than 5% of the liquidation value of a
Portfolio's total assets are required as margin deposits or premiums for such
transactions.  The Portfolios will only sell futures contracts to protect
securities owned against declines in price or purchase contracts to protect
against an increase in the price of securities intended for purchase.  As
evidence of this hedging interest, the Portfolios expect that approximately 75%
of their futures contracts will be "completed"; that is, equivalent amounts of
related securities will have been purchased or are being purchased by the
Portfolios upon sale of open futures contracts.

     Although techniques other than the sale and purchase of futures contracts
could be used to control the Portfolios' exposure to market fluctuations, the
use of futures contracts may be a more effective means of hedging this exposure.
While the Portfolios will incur commission expenses in both opening and closing
out futures positions, these costs are lower than transaction costs incurred in
the purchase and sale of the underlying securities.

RESTRICTIONS ON THE USE OF FUTURES CONTRACTS.  None of the Portfolios will 
enter into futures contract transactions to the extent that, immediately 
thereafter, the sum of its initial margin deposits on open contracts exceeds 
5% of the market value of its total assets.  In addition, none of the 
Portfolios, except the Fixed Income and Global Fixed Income Portfolios, will 
enter into futures contracts to the extent that its outstanding obligations 
to purchase securities under futures contracts and options on futures 
contracts (and in the case of the Active Country Allocation, Equity Growth, 
Gold, Latin American and China Growth Portfolios, under options, futures 
contracts and options on futures contracts) would exceed 20% of its 
respective total assets.



                                       10
<PAGE> 

RISK FACTORS IN FUTURES TRANSACTIONS.  Positions in futures contracts may be
closed out only on an exchange which provides a secondary market for such
futures.  However, there can be no assurance that a liquid secondary market will
exist for any particular futures contracts at any specific time.  Thus, it may
not be possible to close a futures position.  In the event of adverse price
movements, the Portfolios would continue to be required to make daily cash
payments to maintain their required margin.  In such situations, if a Portfolio
has insufficient cash, it may have to sell portfolio securities to meet its
daily margin requirement at a time when it may be disadvantageous to do so.  In
addition, a Portfolio may be required to make delivery of the instruments
underlying futures contracts it holds.  The inability to close options and
futures positions also could have an adverse impact on the Portfolio's ability
to effectively hedge.

     The Portfolios will minimize the risk that they will be unable to close 
out a futures contract by only entering into futures which are traded on 
recognized international or national futures exchanges and for which there 
appears to be a liquid secondary market except that the Equity Growth, 
Aggressive Equity, U.S. Real Estate, Technology and Active Country Allocation
Portfolios may enter into over-the-counter futures transactions to the extent
permitted by applicable law.

     The risk of loss in trading futures contracts in some strategies can be
substantial, due both to the low margin deposits required, and the extremely
high degree of leverage involved in futures pricing.  As a result, a relatively
small price movement in a futures contract may result in immediate and
substantial loss (as well as gain) to the investor.  For example, if, at the
time of purchase, 10% of the value of the futures contract is deposited as
margin, a subsequent 10% decrease in the value of the futures contract would
result in a total loss of the margin deposit, before any deduction for the
transaction costs, if the account were then closed out.  A 15% decrease would
result in a loss equal to 150% of the original margin deposit if the contract
were closed out.  Thus, a purchase or sale of a futures contract may result in
losses in excess of the amount invested in the contract. However, because the
Portfolios engage in futures strategies only for hedging purposes, the Adviser
does not believe that the Portfolios are subject to the risks of loss frequently
associated with futures transactions.  A Portfolio would presumably have
sustained comparable losses if, instead of the futures contract, it had invested
in the underlying security or currency and sold it after the decline.

     Utilization of futures transactions by the Portfolios does involve the risk
of imperfect or no correlation where the securities underlying futures contracts
have different maturities than the portfolio securities or currencies being
hedged.  It is also possible that a Portfolio could both lose money on futures
contracts and also experience a decline in value of its portfolio securities.
There is also the risk of loss by a Portfolio of margin deposits in the event of
bankruptcy of a broker with whom the Portfolio has an open position in a futures
contract or related option.

     Most futures exchanges limit the amount of fluctuation permitted in futures
contract prices during a single trading day.  The daily limit establishes the
maximum amount that the price of a futures contract may vary either up or down
from the previous day's settlement price at the end of a trading session.  Once
the daily limit has been reached in a particular type of contract, no trades may
be made on that day at a price beyond that limit.  The daily limit governs only
price movement during a particular trading day and therefore does not limit
potential losses, because the limit may prevent the liquidation of unfavorable
positions.  Futures contract prices have occasionally moved to the daily limit
for several consecutive trading days with little or no trading, thereby
preventing prompt liquidation of futures positions and subjecting some futures
traders to substantial losses.  For a discussion of the special risks
associated with foreign currency transactions, see "Risks Associated with
Foreign Currency Transactions" in this SAI.


                                       11
<PAGE> 

LOAN PARTICIPATIONS AND ASSIGNMENTS.
   
     The Emerging Markets and Emerging Markets Debt Portfolio may also invest 
in fixed and floating rate loans ("Loans") arranged through private 
negotiations between an issuer of sovereign debt obligations and one or more 
financial institutions ("Lenders").  The Portfolio's investments in Loans are 
expected in most instances to be in the form of participations in Loans 
("Participations") and assignments of all or a portion of Loans 
("Assignments") from third parties.  The Portfolio's investment in 
Participations typically will result in the Portfolio having a contractual 
relationship only with the Lender and not with the borrower.  The Portfolio 
will have the right to receive payments of principal, interest and any fees 
to which it is entitled only from the Lender selling the Participation and 
only upon receipt by the Lender of the payments from the borrower.  In 
connection with purchasing Participations, the Portfolio generally will have 
no right to enforce compliance by the borrower with the terms of the loan 
agreement relating to the Loan, nor any rights of set-off against the 
borrower, and the Portfolio may not directly benefit from any collateral 
supporting the Loan in which it has purchased the Participation. As a result, 
the Portfolio may be subject to the credit risk of both the borrower and the 
Lender that is selling the Participation.  In the event of the insolvency of 
the Lender selling a Participation, the Portfolio may be treated as a general 
creditor of the Lender and may not benefit from any set-off between the 
Lender and the borrower. Certain Participations may be structured in a manner 
designed to avoid purchasers of Participations being subject to the credit 
risk of the Lender with respect to the Participation, but even under such a 
structure, in the event of the Lender's insolvency, the Lender's servicing of 
the Participation may be delayed and the assignability of the Participation 
impaired.  The Portfolio will acquire Participations only if the Lender 
interpositioned between the Portfolio and the borrower is determined by the 
Adviser to be creditworthy.
    
     When the Portfolio purchases Assignments from Lenders it will acquire
direct rights against the borrower on the Loan. Because Assignments are arranged
through private negotiations between potential assignees and potential
assignors, however, the rights and obligations acquired by the Portfolio as the
purchaser of an Assignment may differ from, and be more limited than, those held
by the assigning Lender.  The assignability of certain sovereign debt
obligations is restricted by the governing documentation as to the nature of the
assignee such that the only way in which the Portfolio may acquire an interest
in a loan is through a Participation and not an Assignment.  The Portfolio may
have difficulty disposing of Assignments and Participations because to do so it
will have to assign such securities to a third party.  Because there is no
liquid market for such securities, the Portfolio anticipates that such
securities could be sold only to a limited number of institutional investors.
The lack of a liquid secondary market may have an adverse impact on the value of
such securities and the Portfolio's ability to dispose of particular Assignments
or Participations when necessary to meet the Portfolio's liquidity needs or in
response to a specific economic event such as a deterioration in the
creditworthiness of the borrower.  The lack of a liquid secondary market for
Assignments and Participations also may make it more difficult for the Portfolio
to assign a value to these securities for purposes of valuing the Portfolio's
securities and calculating its net asset value.


                                       12
<PAGE> 

MORGAN STANLEY CAPITAL INTERNATIONAL EAFE INDEX

     The investment objective of the Active Country Allocation Portfolio and 
the International Magnum Portfolio is to provide long-term capital 
appreciation. The Active Country Allocation Portfolio seeks to achieve its 
objective by investing in equity securities of non-U.S. issuers which, in the 
aggregate, replicate broad country indices, in accordance with country 
weightings determined by the Adviser.  The Adviser utilizes a top-down 
approach in selecting investments for the Active Country Allocation Portfolio 
that emphasizes country selection and weighing rather than individual stock 
selection.  The Active Country Allocation Portfolio invests, INTER ALIA, in 
industrialized countries throughout the world that comprise the Morgan 
Stanley Capital International EAFE (Europe, Australia and the Far East) Index 
(the "EAFE Index").  The International Magnum Portfolio seeks to achieve its 
objective by investing primarily in equity securities of non-U.S. issuers 
domiciled in EAFE countries (defined below).  After establishing regional 
allocation strategies, the Adviser then selects equity securities among issuers 
of a region.  The International Magnum Portfolio invests in countries 
comprising the EAFE Index (each an "EAFE country").

     The EAFE Index is one of seven International Indices, twenty National
Indices and thirty-eight International Industry Indices making up the Morgan
Stanley Capital International Indices.   The EAFE Index is based on the share
prices of 1,066 companies listed on the stock exchanges of Europe, Australia,
New Zealand and the Far East. "Europe" includes Austria, Belgium, Denmark,
Finland, France, Germany, Italy, The Netherlands, Norway, Spain, Sweden,
Switzerland and the United Kingdom. "Far East" includes Japan, Hong Kong and
Singapore/Malaysia.

MORTGAGE-BACKED SECURITIES

     Mortgage-Backed Securities are securities that, directly or
indirectly, represent a participation in, or are secured by and payable from,
mortgage loans on real property.  Mortgage-backed securities include
collateralized mortgage obligations, pass-through securities issued or
guaranteed by agencies or instrumentalities of the U.S. government or by
private sector entities.

     COLLATERALIZED MORTGAGE OBLIGATIONS.  Collateralized mortgage
obligations ("CMOs") are debt obligations or multiclass pass-through
certificates issued by agencies or instrumentalities of the U.S. government or
by private originators or investors in mortgage loans.  They are backed by
Mortgage Pass-Through Securities (discussed below) or whole loans (all such
assets, the "Mortgage Assets") and are evidenced by a series of bonds or
certificates issued in multiple classes or "tranches."  The principal and
interest on the underlying Mortgage Assets may be allocated among the several
classes of a series of CMOs in many ways.

     CMOs may be issued by agencies or instrumentalities of the U.S.
government, or by private originators of, or investors in, mortgage loans,
including savings and loan associations, mortgage bankers, commercial banks,
investment banks and special purpose subsidiaries of the foregoing.  CMOs that
are issued by private sector entities and are backed by assets lacking a
guarantee of an entity having the credit status of a governmental agency or
instrumentality are generally structured with one or more types of credit
enhancement as described below.  An issuer of CMOs may elect to be treated, for
federal income tax purposes, as a Real Estate Mortgage Investment Conduit (a
"REMIC").  An issuer of CMOs issued after 1991 must elect to be treated as a
REMIC or it will be taxable as a corporation under rules regarding taxable
mortgage pools.


                                       13
<PAGE> 

     In a CMO, a series of bonds or certificates are issued in multiple
classes.  Each tranche may be issued with a specific fixed or floating
coupon rate and has a stated maturity or final scheduled distribution date.
Principal prepayments on the underlying Mortgage Assets may cause the CMOs to
be retired substantially earlier than their stated maturities or final
scheduled distribution dates.  Interest is paid or accrues on CMOs on a
monthly, quarterly or semi-annual basis.  The principal of and interest on
the Mortgage Assets may be allocated among the several classes of a CMO in
many ways.  The general goal in allocating cash flows on Mortgage Assets to
the various classes of a CMO is to create certain tranches on which the
expected cash flows have a higher degree of predictability than the
underlying Mortgage Assets.  As a general matter, the more predictable the
cash flow is on a particular CMO tranche, the lower the anticipated yield
will be on that tranche at the time of issuance relative to prevailing market
yields on Mortgage Assets. As part of the process of creating more
predictable cash flows on certain tranches of a CMO, one or more tranches
generally must be created that absorb most of the changes in the cash flows
on the underlying Mortgage Assets.  The yields on these tranches are
generally higher than prevailing market yields on Mortgage-Backed Securities
with similar average lives.  Because of the uncertainty of the cash flows on
these tranches, the market prices of and yields on these tranches are more
volatile.

     Included within the category of CMOs are PAC Bonds.  PAC Bonds are a
type of CMO tranche or series designed to provide relatively predictable
payments of principal provided that, among other things, the actual prepayment
experience on the underlying mortgage loans falls within a predefined range.  If
the actual prepayment experience on the underlying mortgage loans is at a rate
faster or slower than the predefined range or if deviations from other
assumptions occur, principal payments on the PAC Bond may be earlier or later
than predicted.  The magnitude of the predefined range varies from one PAC Bond
to another; a narrower range increases the risk that prepayments on the PAC Bond
will be greater or smaller than predicted.  Because of these features, PAC Bonds
generally are less subject to the risks of prepayment than are other types of
mortgage-backed securities.

     MORTGAGE PASS-THROUGH SECURITIES.  Mortgage pass-through securities in 
which the Mortgage-Backed Securities Portfolio may invest include 
pass-through securities issued or guaranteed by agencies or instrumentalities 
of the U.S. government or by private sector entities.  Mortgage pass-through 
securities issued or guaranteed by private sector originators of or investors 
in mortgage loans and are structured similarly to governmental pass-through 
securities. Because private pass-throughs typically lack a guarantee by an 
entity having the credit status of a governmental agency or instrumentality, 
they are generally structured with one or more types of credit enhancement 
described below.  Federal National Mortgage Association ("FNMA" or "Fannie 
Mae") and Federal Home Loan Mortgage Corporation ("FHLMC" or "Freddie Mac") 
obligations are not backed by the full faith and credit of the U.S. 
government as Government National Mortgage Association ("GNMA" or "Ginnie
Mae") certificates are, but FNMA and FHLMC securities are supported by the 
instrumentalities' right to borrow from the U.S. Treasury.  Each of GNMA, 
FNMA and FHLMC guarantees timely distributions of interest to certificate 
holders. Each of GNMA and FNMA also guarantees timely distributions of 
scheduled principal.  FHLMC has in the past guaranteed only the ultimate 
collection of principal of the underlying mortgage loan; however, FHLMC now 
issues Mortgage-Backed Securities (FHLMC Gold Pcs) which also guarantee 
timely payment of monthly principal reductions.  REFCORP obligations are 
backed, as to principal payments, by zero coupon U.S. Treasury bonds, and as 
to interest payment, ultimately by the U.S. Treasury.  Obligations issued by 
such U.S. governmental agencies and instrumentalities are described more 
fully below.


                                       14
<PAGE> 

     GINNIE MAE CERTIFICATES.  Ginnie Mae is a wholly-owned corporate
instrumentality of the United States within the Department of Housing and Urban
Development.  The National Housing Act of 1934, as amended (the "Housing Act"),
authorizes Ginnie Mae to guarantee the timely payment of the principal of and
interest on certificates that are based on and backed by a pool of mortgage
loans insured by the Federal Housing Administration under the Housing Act, or
Title V of the Housing Act of 1949 ("FHA Loans"), or guaranteed by the
Department of Veterans Affairs under the Servicemen's Readjustment Act of 1944,
as amended ("VA Loans"), or by pools of other eligible mortgage loans.  The
Housing Act provides that the full faith and credit of the United States
government is pledged to the payment of all amounts that may be required to be
paid under any guaranty.  In order to meet its obligations under such guaranty,
Ginnie Mae is authorized to borrow from the U.S. Treasury with no
limitations as to amount.

     Each Ginnie Mae Certificate will represent a pro rata interest in one or
more of the following types of mortgage loans: (i) fixed rate level payment
mortgage loans; (ii) fixed rate graduated payment mortgage loans; (iii) fixed
rate growing equity mortgage loans; (iv) fixed rate mortgage loans secured by
manufactured (mobile) homes; (v) mortgage loans on multi-family residential
properties under construction; (vi) mortgage loans on completed multi-family
projects; (vii) fixed rate mortgage loans as to which escrowed funds are used to
reduce the borrower's monthly payments during the early years of the mortgage
loans ("buydown" mortgage loans); (viii) mortgage loans that provide for
adjustments in payments based on periodical changes in interest rates or in
other payment terms of the mortgage loans; and (ix) mortgage-backed serial
notes.  All of these mortgage loans will be FHA Loans or VA Loans and, except as
otherwise specified above, will be fully-amortizing loans secured by first liens
on one- to four-family housing units.

     FANNIE MAE CERTIFICATES.  Fannie Mae is a federally chartered and
privately owned corporation organized and existing under the Federal National
Mortgage Association Charter Act of 1938.  The obligations of Fannie Mae are not
backed by the full faith and credit of the U.S. government.

     Each Fannie Mae Certificate will represent a pro rata interest in one or
more pools of FHA Loans, VA Loans or conventional mortgage loans (i.e., mortgage
loans that are not insured or guaranteed by any governmental agency) of the
following types: (i) fixed rate level payment mortgage loans; (ii) fixed rate
growing equity mortgage loans; (iii) fixed rate graduated payment mortgage
loans; (iv) variable rate California mortgage loans; (v) other adjustable rate
mortgage loans; and (vi) fixed rate and adjustable mortgage loans secured by
multi-family projects.

     FREDDIE MAC CERTIFICATES.  Freddie Mac is a corporate instrumentality of
the United States created pursuant to the Emergency Home Finance Act of 1970, as
amended (the "FHLMC Act").  The obligations of Freddie Mac are obligations
solely of Freddie Mac and are not backed by the full faith and credit of the
U.S. government.

     Freddie Mac Certificates represent a pro rata interest in a group of
mortgage loans (a "Freddie Mac Certificate group") purchased by Freddie Mac.
The mortgage loans underlying the Freddie Mac Certificates will consist of fixed
rate or adjustable rate mortgage loans with original terms to maturity of
between ten and thirty years, substantially all of which are secured by first
liens on one- to four-family residential properties or multi-family projects.
Each mortgage loan must meet the applicable standards set forth in the FHLMC
Act.  A Freddie Mac Certificate group may include whole loans, participation
interests in whole loans and undivided interests in whole loans and
participations comprising another Freddie Mac Certificate group.


                                       15
<PAGE> 

     CREDIT ENHANCEMENT.  Mortgage-backed securities are often backed by a
pool of assets representing the obligations of a number of different parties.
To lessen the effect of failure by obligors on underlying assets to make
payments, such securities may contain elements of credit support.  Such credit
support falls into two categories: (i) liquidity protection and (ii) protection
against losses resulting from ultimate default by an obligor on the underlying
assets.  Liquidity protection generally refers to the provision of advances,
typically by the entity administering the pool of assets, to ensure that the
pass-through of payments due on the underlying pool occurs in a timely fashion.
Protection against losses resulting from ultimate default enhances the
likelihood of ultimate payment of the obligations on at least a portion of the
assets in the pool.  Such protection may be provided through guarantees,
insurance policies or letters of credit obtained by the issuer or sponsor from
third parties (referred to herein as "third party credit support"), through
various means of structuring the transaction or through a combination of such
approaches.  The Mortgage-Backed Securities Portfolio will not pay any
additional fees for such credit support, although the existence of credit
support may increase the price the Portfolio pays for a security.

     The ratings of mortgage-backed securities for which third-party credit
enhancement provides liquidity protection or protection against losses from
default are generally dependent upon the continued creditworthiness of the
provider of the credit enhancement.  The ratings of such securities could be
subject to reduction in the event of deterioration in the creditworthiness of
the credit enhancement provider even in cases where the delinquency and loss
experience on the underlying pool of assets is better than expected.

     Examples of credit support arising out of the structure of the
transaction include "senior-subordinated securities" (multiple class securities
with one or more classes subordinate to other classes as to the payment of
principal thereof and interest thereon, with defaults on the underlying assets
being borne first by the holders of the most subordinated class), creation of
"reserve funds" (where cash or investments, sometimes funded from a portion of
the payments on the underlying assets, are held in reserve against future
losses) and "over-collateralization" (where the scheduled payments on, or the
principal amount of, the underlying assets exceed those required to make payment
of the securities and pay any servicing or other fees).  The degree of credit
support provided for each security is generally based on historical information
with respect to the level of credit risk associated with the underlying assets.
Delinquency or loss in excess of that which is anticipated could adversely
affect the return on an investment in such a security.

MUNICIPAL BONDS

     Municipal Bonds generally include debt obligations issued by states and
their political subdivisions, and duly constituted authorities and corporations,
to obtain funds to construct, repair or improve various public facilities such
as airports, bridges, highways, hospitals, housing, schools, streets and water
and sewer works.  Municipal Bonds may also be issued to refinance outstanding
obligations as well as to obtain funds for general operating expenses and for
loans to other public institutions and facilities.

     The two principal classifications of Municipal Bonds are "general
obligation" and "revenue" or "special tax" bonds.  General obligation bonds are
secured by the issuer's pledge of its full faith, credit and taxing power for
the payment of principal and interest.  Revenue or special tax bonds are payable
only from the revenues derived from a particular facility or class of facilities
or, in some cases, from the proceeds of a special excise or other tax, but not
from general tax revenues.  The Municipal Bond Portfolio and the Municipal Money
Market Portfolio may also invest in tax-exempt industrial development bonds,
short-term municipal obligations, project notes, demand notes and tax-exempt
commercial paper in accordance with the Portfolio's investment objectives and
policies.


                                       16
<PAGE> 

     Industrial revenue bonds (i.e., private activity bonds) in most cases
are revenue bonds and generally do not have the pledge of the credit of the
issuer.  The payment of the principal and interest on such industrial revenue
bonds is dependent solely on the ability of the user of the facilities financed
by the bonds to meet its financial obligations and the pledge, if any, of real
and personal property so financed as security for such payment.  Short-term
municipal obligations issued by states, cities, municipalities or municipal
agencies include Tax Anticipation Notes, Revenue Anticipation Notes, Bond
Anticipation Notes, Construction Loan Notes and Short-Term Discount Notes.
Project Notes are instruments guaranteed by the Department of Housing and Urban
Development but issued by a state or local housing agency.  While the issuing
agency has the primary obligation on such Project notes, they are also secured
by the full faith and credit of the United States.

     Note obligations with demand or put options may have a stated maturity
in excess of one year, but allow any holder to demand payment of principal
plus accrued interest upon a specified number of days notice.  Frequently,
such obligations are secured by letters of credit or other credit support
arrangements provided by banks.  The issuer of such notes normally has a
corresponding right, after a given period, to repay in its discretion the
outstanding principal of the notes plus accrued interest upon a specific
number of days notice to the bondholders.  The interest rate on a demand note
may be based upon a known lending rate, such as a bank's prime rate, and may
be adjusted when such rate changes, or the interest rate on a demand note may
be a market rate that is adjusted at specified intervals.  The demand notes
in which the Municipal Money Market Portfolio will invest are payable on not
more than one year's notice.

     The yields of Municipal Bonds depend on, among other things, general
money market conditions, conditions in the Municipal Bond market, the size of a
particular offering, the maturity of the obligation, and the rating of the
issue.  The ratings of Moody's and S&P represent their opinions of the quality
of the Municipal Bonds.  It should be emphasized that such ratings are general
and are not absolute standards of quality.  Consequently, Municipal Bonds with
the same maturity, coupon and rating may have different yields, while Municipal
Bonds of the same maturity and coupon, but with different ratings, may have the
same yield.  It will be the responsibility of the Adviser to appraise
independently the fundamental quality of the bonds held by the Municipal Bond
Portfolio and the Municipal Money Market Portfolio.

     Municipal Bonds are sometimes purchased on a "when issued" basis meaning
the buyer has committed to purchasing certain specified securities at an
agreed-upon price when they are issued.  The period between commitment date and
issuance date can be a month or more.  It is possible that the securities will
never be issued and the commitment canceled.

     From time to time proposals have been introduced before Congress to
restrict or eliminate the Federal income tax exemption for interest on Municipal
Bonds.  Similar proposals may be introduced in the future.  If any such proposal
were enacted, it might restrict or eliminate the ability of either the Municipal
Bond Portfolio or the Municipal Money Market Portfolio to achieve its investment
objective.  In that event, the Fund's Directors and officers would reevaluate
its investment objective and policies and consider recommending to its
shareholders changes in such objective and policies.

     Similarly, from time to time proposals have been introduced before State
and local legislatures to restrict or eliminate the State and local income tax
exemption (to the extent such an exemption applies, which may not apply in all
cases) for interest on Municipal Bonds.  Similar proposals may be introduced in
the future.  If any such proposal were enacted, it might restrict or eliminate
the ability of either of the Municipal Bond Portfolio or the Municipal Money
Market Portfolio to achieve its investment objective.  In that event, the Fund's
Directors and officers would reevaluate the Portfolio's investment objective and
policies and consider recommending to its shareholders changes in such objective
and policies.


                                       17
<PAGE> 

OPTIONS TRANSACTIONS

GENERAL INFORMATION.  As stated in the applicable Prospectus, the Active 
Country Allocation, Emerging Markets, Emerging Markets Debt, Equity Growth, 
Aggressive Equity, Global Fixed Income, Gold, Small Cap Value Equity, Value 
Equity, Balanced, Latin American, U.S. Real Estate, International Magnum, 
Fixed Income and China Growth Portfolios may purchase and sell
options on portfolio securities and the Fixed Income, Global Fixed Income,
China Growth and Latin American Portfolios also may purchase and sell
options on securities indices.  Additional information with respect to
option transactions is set forth below.  Call and put options on equity
securities are listed on various U.S. and foreign securities exchanges
("listed options") and are written in over-the-counter
transactions ("OTC Options").

     Listed options are issued or guaranteed by the exchange on which they trade
or by a clearing corporation, such as Options Clearing Corporation ("OCC") in
the United States.  Ownership of a listed call option gives the fund the right
to buy from the clearing corporation or exchange, the underlying security
covered by the option at the state exercise price (the price per unit of the
underlying security or currency) by filing an exercise notice prior to the
expiration date of the option.  The writer (seller) of the option would then
have the obligation to sell to the clearing corporation or exchange, the
underlying security or currency at that exercise price prior to the expiration
date of the option, regardless of the current market price.  Ownership of
listed put option would give the Portfolio the right to sell the underlying
security or currency to the clearing corporation or exchange at the state
exercise price.  Upon notice of exercise of the put option, the writer of the
option would have the obligation to purchase the underlying security from the
clearing corporation or exchange at the exercise price.

     OTC options are purchased from or sold (written) to dealers of financial
institutions which have entered into direct agreements with the Portfolio.  With
OTC options, such variables as expiration date, exercise price and premium will
be agreed upon between the Portfolio and the transactions dealer, without the
intermediation of a third party such as a clearing corporation or exchange.  If
the transacting dealer fails to make or take delivery of the securities
underlying an option it has written, in accordance with the terms of that
option, the Portfolio would lose the premium paid for the option as well as any
anticipated benefit of the transaction.

COVERED CALL WRITING.  Each of the Portfolios may write (i.e., sell) covered
call options on portfolio securities.  By doing so, the Portfolio would become
obligated during the terms of the option to deliver the securities underlying
the option should the option holder choose to exercise the option before the
option's termination date.  In return for the call it has written, the Portfolio
will receive from the purchaser (or option holder) a premium which is the price
of the option, less a commission charged by a broker.  The Portfolio will keep
the premium regardless of whether the option is exercised.  A call option is
"covered" if the Portfolio owns the security underlying the option it has
written or has an absolute or immediate right to acquire the security by holding
a call option on such security, or maintains a sufficient amount of cash, cash
equivalents or liquid securities to purchase the underlying security.  When the
Portfolio writes covered call options, it augments its income by the premiums
received and is thereby hedged to the extent of that amount against a decline in
the price of the underlying securities and the premiums received will offset a
portion of the potential loss incurred by the Portfolio if the securities
underlying the options are ultimately sold by the Portfolio at a loss.  However,
during the option period, the Portfolio has, in return for the premium on the
option, given up the opportunity for capital appreciation above the exercise
price should the market price of the underlying security increase, but has
retained the risk of loss should the price of the underlying security decline.
The size of premiums will fluctuate with varying market conditions.


                                       18
<PAGE> 

COVERED PUT WRITING.  Each of the Portfolios may write covered put options on
portfolio securities.  By doing so, the Portfolio incurs an obligation to buy
the security underlying the option from the purchaser of the put at the option's
exercise price at any time during the option period, at the purchaser's election
(certain listed and OTC options written by the Portfolio will be exercisable by
the purchaser only on a specific date).  Generally, a put option is "covered" if
the Portfolio maintains cash or other liquid securities equal to the exercise
price of the option or if the Portfolio holds a put option on the same
underlying security with a similar or higher exercise price.

     Each of the Portfolios may write put options to receive the premiums paid
by purchasers; when the Adviser (and also the Sub-Adviser with respect to the
Gold Portfolio) wishes to purchase the security underlying the option at a price
lower than its current market price, in which case it will write the covered put
at an exercise price reflecting the lower purchase price sought; and to close
out long put option positions.

PURCHASE OF PUT AND CALL OPTIONS.  Each of the Portfolios may purchase listed or
OTC put or call options on its portfolio securities in amounts exceeding no more
than 5% of its total assets.  When the Portfolio purchases a call option it
acquires the right to purchase a designated security at a designated price (the
"exercise price"), and when the Portfolio purchases a put option it acquires the
right to sell a designated security at the exercise price, in each case on
or before a specified date (the "termination date"), usually not more than nine
months from the date the option is issued.

     The Portfolio may purchase call options to close out a covered call
position or to protect against an increase in the price of a security it
anticipates purchasing.  The Portfolio may purchase put options on securities
which it holds in its portfolio only to protect itself against a decline in the
value of the security.  If the value of the underlying security were to fall
below the exercise price of the put purchased in an amount greater than the
premium paid for the option, the Portfolio would incur no additional loss.  The
Portfolio may also purchase put options to close out written put positions in a
manner similar to call option closing purchase transactions.

     The amount the Portfolio pays to purchase an option is called a "premium",
and the risk assumed by the Portfolio when it purchases an option is the loss of
this premium.  Because the price of an option tends to move with that of its
underlying security, if the Portfolio is to make a profit, the price of the
underlying security must change and the change must be sufficient to cover the
premium and commissions paid.  A price change in the security underlying the
option does not assure a profit since prices in the options market may not
always reflect such a change.

OPTIONS ON SECURITIES INDICES.   The China Growth and Latin American Portfolios
may purchase and write put and call options on securities indices and enter into
related closing transactions in order to hedge against the risk of market
price fluctuations or to increase income to the Portfolio.

     Call and put options on indices are similar to options on securities except
that, rather than the right to purchase or sell particular securities at a
specified price, options on an index give the holder the right to receive, upon
exercise of the option, an amount of cash if the closing level of the underlying
index is greater than (or less than, in the case of puts) the exercise price of
the option.  This amount of cash is equal to the difference between the closing
price of the index and the exercise price of the option, expressed in dollars
multiplied by a specified number.  Thus, unlike options on individual
securities, all settlements are in cash, and gain or loss depends on price
movements in the particular market represented by the index generally (or in a
particular industry or segment of the market) rather than the price movements in
individual securities.


                                       19
<PAGE> 

     All options written on indices must be covered.  When the Portfolio writes
an option on an index, it will establish a segregated account containing cash
liquid securities with its custodian in an amount at least equal to the market
value of the option and will maintain the account while the option is open or
will otherwise cover the transaction.

     The Portfolio may choose to terminate an option position by entering into a
closing transaction.  The ability of the Portfolio to enter into closing
transactions depends upon the existence of a liquid secondary market for such
transactions.

OPTIONS ON CURRENCIES.  The Fixed Income, Global Fixed Income China Growth, 
Emerging Markets Debt, International Magnum and Latin American
Portfolios may purchase and write put and call options on foreign
currencies (traded on U.S. and foreign exchanges or over-the-counter
markets) to manage the Portfolio's exposure to changes in dollar
exchange rates.  Call options on foreign currency written by the 
Portfolio will be "covered," which means that the Portfolio will own an equal 
amount of the underlying foreign currency.  With respect to put options on 
foreign currency written by the Portfolio, the Portfolio will establish a 
segregated account with the Fund's Custodian consisting of cash
or liquid securities in an amount equal to the amount the Portfolio would be
required to pay upon exercise of the put.

RISK FACTORS IN OPTIONS TRANSACTIONS. The use of options also involves 
additional risks.  Compared to the purchase or sale of futures contracts, the 
purchase of call or put options involves less potential risk to a Portfolio 
because the maximum amount of risk is the premium paid for the option.  The 
writing of a call option generates a premium which may partially offset a 
decline in the value of a Portfolio's portfolio assets.  By writing a call 
option, the Portfolio becomes obligated to sell the underlying instrument, 
which may have a value higher than the exercise price.  Conversely, the 
writing of a put option generates a premium, but the Portfolio becomes 
obligated to purchase the underlying instrument, which may have a value lower 
than the exercise price. Thus, the loss incurred by a Portfolio in writing 
options may exceed the amount of the premium received.

     The effective use of options strategies is dependent, among other
things, on a Portfolio's ability to terminate options positions at a time
when the portfolio manager deems it desirable to do so.  Although a Portfolio
will enter into options positions only if the portfolio manager believes that
a liquid secondary market exists for such options, there is no assurance that
the Portfolio will be able to effect closing transactions at any particular
time or at an acceptable price.

     A Portfolio's purchase or sale of put or call options will be based upon
predictions as to anticipated market trends and/or interest rate movements by
the portfolio manager, which could prove to be inaccurate.  Even if the
expectations of the portfolio manager are correct, there may be an imperfect
correlation between the change in the value of the options and of the
Portfolio's portfolio securities.

     The writer of an option may have no control over when the underlying
securities must be sold, in the case of a call option, or purchased, in the
case of a put option; the writer may be assigned an exercise notice at any
time prior to the termination of the obligation.  Whether or not an option
expires unexercised, the writer retains the amount of the premium.  This
amount, of course, may, in the case of a covered call option, be offset by a
decline in the market value of the underlying security during the option
period.  If a call option is exercised, the writer experiences a profit or
loss from the sale of the underlying security.  If a put option is exercised,
the writer must fulfill the obligation to purchase the underlying security at
the exercise price which will usually exceed the then market value of the
underlying security.


                                       20
<PAGE> 

     The writer of an option that wishes to terminate its obligation may
effect a "closing purchase transaction."  This is accomplished by buying an
option of the same series as the option previously written.  The effect of
the purchase is that the writer's position will be canceled by the clearing
corporation.  However, a writer may not effect a closing purchase transaction
after being notified of the exercise of an option.  Likewise, an investor who
is the holder of an option may liquidate its position by effecting a "closing
sale transaction."  This is accomplished by selling an option of the same
series as the option previously purchased.  There is no guarantee that either
a closing purchase or a closing sale transaction can be effected.

     Effecting a closing transaction in the case of a written call option
will permit the Portfolio to write another call option on the underlying
security with either a different exercise price or expiration date or both,
in the case of a written put option, will permit the Portfolio to write
another put option to the extent that the exercise price thereof is secured
by depositing liquid assets.  Also, effecting a closing transaction will
permit the cash or proceeds from the concurrent sale of any securities
subject to the option to be used for other Portfolio investments.  If the
Portfolio desires to sell a particular security from its portfolio on which
it has written a call option, it will effect a closing transaction prior to or
concurrent with the sale of the security.

     A Portfolio will realize a profit from a closing transaction if the price
of the transaction is less than the premium received from writing the option or
is more than the premium paid to purchase the option; the Portfolio will realize
a loss from a closing transaction if the price of the transaction is more than
the premium received from writing the option or is less than the premium paid to
purchase the option. Because increases in the market price of a call option will
generally reflect increases in the market price of the underlying security, any
loss resulting from the repurchase of a call option is likely to be offset in
whole or in part by appreciation of the underlying security owned by the
Portfolio.

     An options position may be closed out only where there exists a 
secondary market for an option of the same series.  If a secondary market 
does not exist, it might be possible to effect a closing transaction in 
particular options with the result that the Portfolio would have to exercise 
the options in order to realize any profit.  If the Portfolio is unable to 
effect a closing purchase transaction in a secondary market, it will not be 
able to sell the underlying security until the option expires or it delivers 
the underlying security upon exercise.  Reasons for the absence of a liquid 
secondary market include the following:  (1) there may be insufficient 
trading interest in certain options, (2) restrictions may be imposed by an 
exchange on opening transactions or closing transactions, or both, (3) 
trading halts, suspensions or other restrictions may be imposed with respect 
to particular classes or series of options or underlying securities, (4) 
unusual or unforeseen circumstances may interrupt normal operation on an 
exchange, (5) the facilities of an exchange or OCC may not at all times be 
adequate to handle current trading volume, or (6) one or more exchange could, 
for economic or other reasons, decide or be compelled at some future date to 
discontinue the trading of options (or a particular class or series of 
options), in which event the secondary market on that Exchange (or in that 
class or series of options) would cease to exist, although outstanding 
options on that exchange that had been issued by OCC as a result of trades on 
that exchange would continue to be exercisable in accordance with their terms.

     The Portfolios may purchase put options to hedge against a decline in
the value of their portfolios.  By using put options in this way, the
Portfolios will reduce any profit they might otherwise have realized in the
underlying security by the amount of the premium paid for the put option and
by transaction costs.


                                       21
<PAGE> 

     The Portfolios may purchase call options to hedge against an increase in
the price of securities that the Portfolios anticipate purchasing in the
future.  The premium paid for the call option plus any transaction costs will
reduce the benefit, if any, realized by a Portfolio upon exercise of the
option, and, unless the price of the underlying security rises sufficiently,
the option may expire worthless.

     Options may also be traded OTC ("OTC Options").  In an OTC trading
environment, many of the protections afforded to exchange participants will
not be available.  For example, there are no daily price fluctuation limits,
and adverse market movements could therefore continue to an unlimited extent
over a period of time.  The Portfolios may purchase or write OTC Options
deemed creditworthy by the Adviser.  OTC Options are illiquid and it may not
be possible for the Portfolios to dispose of such options they have purchased
or terminate their obligations under an option they have written at a time
when the Adviser and portfolio manager believe it would be advantageous to do
so.  Accordingly, OTC Options are subject to the Portfolios' limitation that
a maximum of 15% of its net assets be invested in illiquid securities.  In
the event of the bankruptcy of the writer of an OTC Option, the Portfolios
could experience a loss of all or part of the value of the option.

     For a discussion regarding the special risks of foreign currency
options, see "Risks Associated with Foreign Currency Transactions," in this
SAI.

PORTFOLIO TURNOVER

     The portfolio turnover rate for a year is the lesser of the value of the
purchases or sales for the year divided by the average monthly market value of
the Portfolio for the year, excluding U.S. Government securities and securities
with maturities of one year or less.  The portfolio turnover rate for a year is
calculated by dividing the lesser of sales or the average monthly value of the
Portfolio's portfolio purchases of portfolio securities during that year by
securities, excluding money market instruments.  The rate of portfolio turnover
will not be a limiting factor when the Portfolio deems it appropriate to
purchase or sell securities for the Portfolio.  However, the U.S. federal tax
requirement that the Portfolio derive less than 30% of its gross income from the
sale or disposition of securities held less than three months may limit the
Portfolio's ability to dispose of its securities.  See "Taxes."

PRECIOUS METALS FORWARD AND FUTURES CONTRACTS AND OPTIONS ON FUTURES CONTRACTS

     The Gold Portfolio may enter into futures contacts on precious metals
("precious metals futures") as a hedge against changes in the prices of
precious metals held or intended to be acquired by the Portfolio, but not for
speculation or for achieving leverage.  The Portfolio's hedging activities
may include purchases of futures contracts as an offset against the effect of
anticipated increases in the price of a precious metal which the Portfolio
intends to acquire ("anticipatory hedge") or sales of futures contracts as an
offset against the effect of anticipated declines in the price of precious
metal which the Portfolio owns ("hedge against an existing position").
   
     The Portfolio will enter into precious metals forward contracts which are
similar to precious metals futures contracts, in that they provide for the
purchase or sale of precious metals at an agreed price with delivery to take
place at an agreed future time.  However, unlike futures contracts, forward
contracts are negotiated contracts which are primarily used in the dealer
market.  Unlike the futures contract market, which is regulated by the CFTC and
by the regulations of the commodity exchanges, the forward contract market is
unregulated.  The Portfolio will use forward contracts for the same hedging
purposes as those applicable to futures contracts, as described above.  When the
Portfolio enters into a forward contract it will establish with the custodian a
segregated account consisting of cash, liquid assets or bullion equal to the
market value of the forward contract purchased.
    

                                       22
<PAGE> 

     Precious metals futures and forward contract prices can be volatile and are
influenced principally by changes in spot market prices, which in turn are
affected by a variety of political and economic factors.  In addition,
expectations of changing market conditions may at times influence the prices of
such futures and forward contracts, and changes in the cost of holding physical
precious metals, including storage, insurance and interest expense, will also
affect the relationship between spot and futures or forward prices.  While the
correlation between changes in prices of futures and forward contracts and
prices of the precious metals being hedged by such contracts has historically
been very strong, the correlation may at times be imperfect and even a well
conceived hedge may be unsuccessful to some degree because of market behavior or
unexpected precious metals price trends.  To the extent that interest rates move
in a direction opposite to that anticipated, the Portfolio may realize a loss on
a futures transaction not offset by an increase in the value of portfolio
securities.  Moreover there is a possibility of a lack of a liquid secondary
market for closing out a futures position or futures option.  The success of any
hedging technique depends upon the Adviser's and Sub-Adviser's accuracy in
predicting the direction of a market.  If these predictions are incorrect, the
Portfolio may realize a loss.

     The Portfolio may also purchase (buy) and write (sell) covered call or put
options on precious metals futures contracts.  Such options would be purchased
solely for hedging purposes similar to those applicable to the purchase and sale
of futures contracts.  Call options might be purchased to hedge against an
increase in the price of precious metals the Portfolio intends to acquire, and
put options may be purchased to hedge against a decline in the price of precious
metals owned by the Portfolio.  As is the case with futures contracts, options
on precious metals futures may facilitate the Portfolio's acquisition of
precious metals or permit the Portfolio to defer disposition of precious metals
for tax or other purposes.  The Portfolio may not purchase options on precious
metals and precious metals futures contracts if the premiums paid for all such
options, together with margin deposits on precious metals future contracts,
would exceed 5% of the Portfolio's total assets at the time the option is
purchased.

     One of the risks which may arise in employing futures contracts to protect
against the price volatility of the Portfolio's assets is that the price of
precious metals subject to futures contracts (and thereby the futures contracts
prices) may correlate imperfectly with the prices of such assets.  A correlation
may also be distorted by the fact that the futures market is dominated by short-
term traders seeking to profit from the difference between a contract or
security price objective and their cost of borrowed funds.  Such distortions are
generally minor and would diminish as the contract approached maturity.

SECURITIES LENDING
   
     Each Portfolio may lend its investment securities to qualified 
institutional investors who need to borrow securities in order to complete 
certain transactions, such as covering short sales, avoiding failures to 
deliver securities or completing arbitrage operations.  By lending its 
investment securities, a Portfolio attempts to increase its net investment 
income through the receipt of interest on the loan.  Any gain or loss in the 
market price of the securities loaned that might occur during the term of the 
loan would be for the account of the Portfolio.  Each Portfolio may lend its 
investment securities to qualified brokers, dealers, domestic and foreign 
banks or other financial institutions, so long as the terms, structure and 
the aggregate amount of such loans are not inconsistent with the 1940 Act, or 
the Rules and Regulations or interpretations of the Commission thereunder, 
which currently require that (a) the borrower pledge and maintain with the 
portfolio collateral consisting of cash, an irrevocable letter of credit 
issued by a domestic U.S. bank, or securities issued or guaranteed by the 
United States Government having a value at all times not less than 100% of 
the value of the securities loaned, (b) the borrower add to such collateral 
whenever the price of the securities

                                       23
<PAGE> 


loaned rises (i.e., the borrower "marks to the market" on a daily basis), (c)
the loan be made subject to termination by the Portfolio at any time, and (d)
the Portfolio receive reasonable interest on the loan (which may include the
Portfolio investing any cash collateral in interest bearing short-term
investments), any distributions on the loaned securities and any increase in
their market value.  There may be risks of delay in recovery of the
securities or even loss of rights in the collateral should the borrower of
the securities fail financially.  However, loans will only be made to
borrowers deemed by the Adviser or Sub-Adviser to be of good standing and
when, in the judgment of the Adviser or Sub-Adviser, the consideration which
can be earned currently from such securities loans justifies the attendant
risk. All relevant facts and circumstances, including the creditworthiness of
the broker, dealer or institution, will be considered in making decisions
with respect to the lending of securities, subject to review by the Board of
Directors of the Fund.
    

     At the present time, the staff of the Commission does not object if an
investment company pays reasonable negotiated fees in connection with loaned
securities, so long as such fees are set forth in a written contract and
approved by the investment company's Board of Directors.  In addition, voting
rights may pass with the loaned securities, but if a material event will occur
affecting an investment on loan, the loan must be called and the securities
voted.

SHORT SALES

     The Emerging Markets Debt, Latin American and Aggressive Equity
Portfolios may from time to time sell securities short without limitation but
consistent with applicable legal requirements, although at present the
Portfolios do not intend to sell securities short.  A short sale is a
transaction in which the Portfolio would sell securities it owns or has the
right to acquire at no added cost (i.e., "against the box") or does not own
(but has borrowed) in anticipation of a decline in the market price of the
securities.  When the Portfolio makes a short sale of borrowed securities,
the proceeds it receives from the sale will be held on behalf of a broker
until the Portfolio replaces the borrowed securities.  To deliver the
securities to the buyer, the Portfolio will need to arrange through a broker
to borrow the securities and, in so doing, the Portfolio will become
obligated to replace the securities borrowed at their market price at the
time of replacement, whatever that price may be.  The Portfolio may have to
pay a premium to borrow the securities and must pay any dividends or interest
payable on the securities until they are replaced.
   
     The Portfolio's obligation to replace the securities borrowed in 
connection with a short sale will be secured by collateral deposited with the 
broker that consists of cash or liquid securities. In addition, if the short
sale is not "against the box," the Portfolio will place in a segregated
account with its custodian, or designated sub-custodian, an amount of cash or
liquid securities equal to the difference, if any, between the market
value of the securities sold short and any cash or liquid securities deposited
as collateral with the broker in connection with the short sale. Until it
replaces the borrowed securities, the Portfolio will maintain the segregated
account daily at a level so that the amount deposited in the account plus the
amount deposited with the broker will equal the current market 
value of the securities sold short.

    
                                       24
<PAGE> 

     Short sales by the Portfolio involve certain risks and special
considerations.  Possible losses from short sales differ from losses that could
be incurred from a purchase of a security, because losses from short sales may
be unlimited, whereas losses from purchases can equal only the total amount
invested.


U.S. GOVERNMENT SECURITIES

     The term "U.S. Government securities" refers to a variety of securities
which are issued or guaranteed by the U.S. Government, and by various
instrumentalities which have been established or sponsored by the U.S.
Government.
   
     U.S. Treasury securities are backed by the "full faith and credit" of 
the United States. Securities issued or guaranteed by Federal agencies and 
U.S. Government sponsored instrumentalities may or may not be backed by the 
full faith and credit of the United States.  In the case of securities not 
backed by the full faith and credit of the United States, the investor must 
look principally to the agency or instrumentality issuing or guaranteeing the 
obligation for ultimate repayment, and may not be able to assert a claim 
against the United States itself in the event the agency or instrumentality 
does not meet its commitment. Agencies which are backed by the full faith and 
credit of the United States include the Export-Import Bank, Farmers Home 
Administration, Federal Financing Bank, and others.  Certain agencies and 
instrumentalities, such as the GNMA, are, in effect, backed by the full faith 
and credit of the United States through provisions in their charters that 
they may make "indefinite and unlimited" drawings on the Treasury, if needed 
to service debt.  Debt from certain other agencies and instrumentalities, 
including the Federal Home Loan Bank and FNMA, are not guaranteed by the 
United States, but those institutions are protected by the discretionary 
authority for the U.S. Treasury to purchase certain amounts of their 
securities to assist the institution in meeting its debt obligations.  
However, the U.S. Treasury has no lawful obligation to assume the financial 
liabilities of these agencies or others. Finally, other agencies and 
instrumentalities, such as the Farm Credit System and the FHLMC, are 
federally chartered institutions under Government supervision, but their debt 
securities are backed only by the creditworthiness of those institutions, not 
the U.S. Government.
    
     Some of the U.S. Government agencies that issue or guarantee securities
include the Export-Import Bank of the United States, Farmers Home
Administration, Federal Housing Administration, Maritime Administration, Small
Business Administration, and the Tennessee Valley Authority.
   
     An instrumentality of the U.S. Government is a Government agency
organized under Federal charter with Government supervision.  Instrumentalities
issuing or guaranteeing securities include, among others, Federal Home Loan
Banks, the Federal Land Banks, Central Bank for Cooperatives, Federal Immediate
Credit Banks, and the FNMA.
    
                                      TAXES

     The following is only a summary of certain additional federal tax
considerations generally affecting the Fund and its shareholders that are not
described in the Prospectuses.  No attempt is made to present a detailed
explanation of the federal, state or local tax treatment of the Fund or its
shareholders, and the discussion here and in the Fund's Prospectuses is not
intended as a substitute for careful tax planning.

     The following discussion of federal income tax consequences is based on
the Internal Revenue Code of 1986, as amended (the "Code") and the
regulations issued thereunder as in effect on the date of this Statement of
Additional Information.  New legislation, as well as administrative changes
or court decisions, may significantly change the conclusions expressed
herein, and may have a retroactive effect with respect to the transactions
contemplated herein.

     Each Portfolio within the Fund is generally treated as a separate
corporation for federal income tax purposes, and thus the provisions of the Code
generally will be applied to each Portfolio separately, rather than to the Fund
as a whole.

              GENERAL REGULATED INVESTMENT COMPANY QUALIFICATIONS

     Each Portfolio intends to qualify and elect to be treated for each taxable
year as a regulated investment company ("RIC") under Subchapter M of the Code.
Accordingly, each Portfolio must, among other things, (a) derive at least 90% of
its gross income each taxable year from dividends, interest, payments with
respect to securities loans, gains from the sale or other disposition of stock,
securities or foreign currencies, and certain other related income, including,
generally, certain gains from options, futures and forward contracts; (b) derive
less than 30% of its gross income each taxable year from the sale or other
disposition of the following items if held less than three months (A) stock or
securities, (B) options, futures or forward contracts (other than options,
futures or forward contracts on foreign currencies), and (C) foreign currencies
(or options, futures, or forward contracts on foreign currencies) that are not
directly related to the Portfolio's principal business of investing in stocks or
securities (or options or futures with respect to stock or securities) (the
"short-short test"); and (c) diversify its holdings so that, at the end of each
fiscal quarter of the Portfolio's taxable year, (i) at least 50% of the market
value of the Portfolio's total assets is represented by cash and cash items,
United States Government securities, securities of other RICs, and other
securities, with such other securities limited, in respect to any one issuer, to
an amount not greater than 5% of the value of the Portfolio's total assets or
10% of the outstanding voting securities of such issuer, and (ii) not more than
25% of the value of its total assets is invested in the securities (other than
United States Government securities or securities of other RICs) of any one
issuer or two or more issuers which the Portfolio controls and which are engaged
in the same, similar, or related trades or business.  For purposes of the 90% of
gross income requirement described above, foreign currency gains which are not
directly related to a Portfolio's principal business of investing in stock or
securities (or options or futures with respect to stock or securities) may be
excluded from income that qualifies under the 90% requirement.

     In addition to the requirements described above, in order to qualify as 
a RIC, a Portfolio must distribute at least 90% of its net investment income 
(which generally includes dividends, taxable interest, and the excess of net 
short-term capital gains over net long-term capital losses less operating 
expenses) and at least 90% of its net tax-exempt interest income, for each 
tax year, if any, to its shareholders.  If a Portfolio meets all of the RIC 
requirements, it will not be subject to federal income tax on any of its net 
investment income or capital gains that it distributes to shareholders.



                                       25
<PAGE> 

     If a Portfolio fails to qualify as a RIC for any year, all of its income
will be subject to tax at corporate rates, and its distributions (including
capital gains distributions) will be taxable as ordinary income dividends to its
shareholders to the extent of the Portfolio's current and accumulated earnings
and profits, and will be eligible for the corporate dividends received deduction
for corporate shareholders.

           GENERAL TAX TREATMENT OF QUALIFYING RICs AND SHAREHOLDERS

     Each Portfolio will decide whether to distribute or to retain all or part
of any net capital gains (the excess of net long-term capital gains over net
short-term capital losses) in any year for reinvestment.  If any such gains are
retained, the Portfolio will pay federal income tax thereon, and, if the
Portfolio makes an election, the shareholders will include such undistributed
gains in their income, will increase their basis in Portfolio shares by 65% of
the amount included in their income and will be able to claim their share of the
tax paid by the Portfolio as a refundable credit.

     A gain or loss realized by a shareholder on the sale, exchange or
redemption of shares of a Portfolio held as a capital asset will be capital
gain or loss, and such gain or loss will be long-term if the holding period
for the shares exceeds one year, and otherwise will be short-term.  Any loss
realized on a sale, exchange or redemption of shares of a Portfolio will be
disallowed to the extent the shares disposed of are replaced within the
61-day period beginning 30 days before and ending 30 days after the shares
are disposed of.  Any loss realized by a shareholder on the disposition of
shares held 6 months or less is treated as a long-term capital loss to the
extent of any distributions of net long-term capital gains received by the
shareholder with respect to such shares or any inclusion of undistributed
capital gain with respect to such shares.

     The conversion of Class A shares to Class B shares should not be a taxable
event to the shareholder.

     Each Portfolio will generally be subject to a nondeductible 4% federal
excise tax to the extent it fails to distribute by the end of any calendar year
at least 98% of its ordinary income for that year and 98% of its capital gain
net income (the excess of short- and long-term capital gains over short- and
long-term capital losses) for the one-year period ending on October 31 of that
year, plus certain other amounts.

     Each Portfolio is required by federal law to withhold 31% of reportable
payments (which may include dividends, capital gains distributions, and
redemptions) paid to shareholders who have not certified on the Account
Registration Form or on a separate form supplied by the Portfolio, that the
Social Security or Taxpayer Identification Number provided is correct and that
the shareholder is exempt from backup withholding or is not currently subject to
backup withholding.

     A Section 1256 position held by a Fund will generally be marked-to-market
(i.e. treated as if it were sold for fair market value) on the last business
day of a Fund's fiscal year, and all gain or loss associated with fiscal year
transactions and mark-to-market positions at fiscal year end (except certain
currency gain or loss covered by Section 988 of the Code) will generally be
treated as 60% long-term capital gain or loss and 40% short-term capital gain
or loss. The effect of Section 1256 mark-to-market rules may be to accelerate
income or to convert what otherwise would have been long-term capital gains
into short-term capital gains or short-term capital losses into long-term
capital losses within a Fund. The acceleration of income on Section 1256
positions may require a Fund to accrue taxable income without the
corresponding receipt of cash. In order to generate cash to satisfy the
distribution requirements of the Code, a Fund may be required to dispose of
portfolio securities that they otherwise would have continued to hold or to
use cash flows from other sources such as the sale of Fund shares. In these
ways, any or all of these rules may affect the amount, character and timing
of income earned and in turn distributed to shareholders by a Fund.


                                       26
<PAGE> 

     As discussed above, in order for each Portfolio to continue to qualify for
federal income tax treatment as a RIC, at least 90% of its gross income for a
taxable year must be derived from certain qualifying income, including
dividends, interest, income derived from loans of securities, and gains from the
sale or other disposition of stock, securities or foreign currencies, or other
related income, including gains from options, futures and forward contracts,
derived with respect to its business of investing in stock, securities or
currencies.  Any net gain realized from the closing out of futures contracts
will therefore generally be qualifying income for purposes of the 90%
requirement.  Qualification as a RIC also requires that less than 30% of a
Portfolio's gross income be derived from the sale or other disposition of stock,
securities, options, futures or forward contracts (including certain foreign
currencies not directly related to the Fund's business of investing in stock or
securities) held less than three months.  In order to avoid realizing excessive
gains on futures contracts held less than three months, the Portfolio may be
required to defer the closing out of futures contracts beyond the time when it
would otherwise be advantageous to do so.

     Short sales engaged in by a Portfolio may reduce the holding property held
by a Portfolio which is substantially identical to the property sold short.
This rule may make it more difficult for the Portfolio to satisfy the short-
short test.  This rule may also have the effect of converting capital gains
recognized by the Portfolio from long-term to short-term as well as converting
capital losses recognized by the Portfolio from short-term to long-term.

     SPECIAL RULES FOR CERTAIN FOREIGN CURRENCY TRANSACTIONS.  In general,
gains from foreign currencies and from foreign currency options, foreign
currency futures and forward foreign exchange contracts relating to
investments in stock, securities or foreign currencies are currently
considered to be qualifying income for purposes of determining whether the
Fund qualifies as a regulated investment company. It is currently unclear,
however, who will be treated as the issuer of certain foreign currency
instruments or how foreign currency options, futures, or forward foreign
currency contracts will be valued for purposes of the regulated investment
company diversification requirements applicable to the Fund. The Fund may
request a private letter ruling from the Internal Revenue Service on some or
all of these issues.

     Under Code Section 988, special rules are provided for certain
transactions in a foreign currency other than the taxpayer's functional
currency (i.e., unless certain special rules apply, currencies other than the
U.S. dollar). In general, foreign currency gains or losses from forward
contracts, from futures contracts that are not "regulated futures contracts",
and from unlisted options will be treated as ordinary income or loss under
Code Section 988. Also, certain foreign exchange gains or losses derived with
respect to foreign fixed-income securities are also subject to Section 988
treatment. In general, therefore, Code Section 988 gains or losses will
increase or decrease the amount of the Fund's investment company taxable
income available to be distributed to shareholders as ordinary income, rather
than increasing or decreasing the amount of the Fund's net capital gain.

     If the Fund invests in an entity which is classified as a "passive
foreign investment company" ("PFIC") for U.S. tax purposes, the application
of certain technical tax provisions applying to such companies could result
in the imposition of federal income tax with respect to such investments at
the Fund level which could not be eliminated by distributions to
shareholders. The U.S. Treasury issued proposed regulation section 1.1291-8
which establishes a mark-to-market regime which allows investment companies
investing in PFIC's to avoid most, if not all, of the difficulties posed by
the PFIC rules. In any event, it is not anticipated that any taxes on the
Fund with respect to investments in PFIC's would be significant.


                                       27
<PAGE> 

     A Fund's investment in options, swaps and related transactions, futures
contracts and forward contracts, options on futures contracts and stock
indices and certain other securities, including transactions involving actual
or deemed short sales or foreign exchange gains or losses are subject to many
complex and special tax rules. For example, over-the-counter options on debt
securities and equity options, including options on stock and on narrow-based
stock indexes, will be subject to tax under Section 1234 of the Code,
generally producing a long-term or short-term capital gain or loss upon
exercise, lapse or closing out of the option or sale of the underlying stock
or security. By contrast, a Fund's treatment of certain other options,
futures and forward contracts entered into by a Fund is generally governed by
Section 1256 of the Code. These "Section 1256" positions generally include
listed options on debt securities, options on broad-based stock indexes,
options on securities indexes, options on futures contracts, regulated
futures contracts and certain foreign currency contracts and options thereon.

     When a Fund holds options or contracts which substantially diminish
their risk of loss with respect to other positions (as might occur in some
hedging transactions), this combination of positions could be treated as a
"straddle" for tax purposes, resulting in possible deferral of losses,
adjustments in the holding periods of Fund securities and conversion of
short-term capital losses into long-term capital losses. Certain tax
elections exist for mixed straddles i.e., straddles comprised of at least one
Section 1256 position and at least one non-Section 1256 position which may
reduce or eliminate the operation of these straddle rules.

                     SPECIAL TAX CONSIDERATIONS RELATING TO
                               MUNICIPAL BOND AND
                        MUNICIPAL MONEY MARKET PORTFOLIOS

     Each of the Municipal Bond Portfolio and the Municipal Money Market
Portfolio will qualify to pay "exempt interest dividends" to its shareholders
provided that, at the close of each quarter of its taxable year at least 50% of
the value of its total assets consists of obligations the interest on which is
exempt from federal income tax.  Current federal tax law limits the types and
volume of bonds qualifying for federal income tax exemption of interest, which
may have an effect on the ability of these Portfolios to purchase sufficient
amounts of tax-exempt securities to satisfy this requirement.  Any loss on the
sale or exchange of shares of the Municipal Bond Portfolio or the Municipal
Money Market Portfolio held for six months or less will be disallowed to the
extent of any exempt-interest dividends received by the selling shareholder with
respect to such shares.


                                       28
<PAGE> 

     As noted in the Prospectus for the Municipal Bond Portfolio and the
Municipal Money Market Portfolio, exempt-interest dividends are excludable from
a shareholder's gross income for regular Federal income tax purposes.  Exempt-
interest dividends may nevertheless be subject to the alternative minimum tax
(the "Alternative Minimum Tax") imposed by Section 55 of the Code or the
environmental tax (the "Environmental Tax") imposed by Section 59A of the Code.
The Alternative Minimum Tax is imposed at the rate of up to 28% in the case of
non-corporate taxpayers and at the rate of 20% in the case of corporate
taxpayers, to the extent it exceeds the taxpayer's regular tax liability.  The
Environmental Tax is imposed at the rate of 0.12% and applies only to corporate
taxpayers.  The Alternative Minimum Tax and the Environmental Tax may be
affected by the receipt of exempt-interest dividends in two circumstances.
First, exempt-interest dividends derived from certain "private activity bonds"
issued after August 7, 1986, will generally be an item of tax preference and
therefore potentially subject to the Alternative Minimum Tax and the
Environmental Tax.  The Portfolios intend, when possible, to avoid investing in
private activity bonds.  Second, in the case of exempt-interest dividends
received by corporate shareholders, all exempt-interest dividends, regardless of
when the bonds from which they are derived were issued or whether they are
derived from private activity bonds, will be included in the corporation's
"adjusted current earnings," as defined in Section 56(g) of the Code, in
calculating the corporation's alternative minimum taxable income for purposes of
determining the Alternative Minimum Tax and the Environmental Tax.

     The percentage of income that constitutes "exempt-interest dividends" will
be determined for each year for the Municipal Bond Portfolio and the Municipal
Money Market Portfolio and will be applied uniformly to all dividends declared
with respect to the Portfolios during that year.  This percentage may differ
from the actual percentage for any particular day.

     Interest on indebtedness incurred or continued by shareholders to purchase
or carry shares of the Municipal Bond Portfolio or the Municipal Money Market
Portfolio will not be deductible for federal income tax purposes.  The deduction
otherwise allowable to property and casualty insurance companies for "losses
incurred" will be reduced by an amount equal to a portion of exempt-interest
dividends received or accrued during any taxable year.  Foreign corporations
engaged in a trade or business in the United States will be subject to a "branch
profits tax" on their "dividend equivalent amount" for the taxable year, which
will include exempt-interest dividends.  Certain Subchapter S corporations may
also be subject to taxes on their "passive investment income," which could
include exempt-interest dividends.  Up to 85% of the Social Security benefits or
railroad retirement benefits received by an individual during any taxable year
will be included in the gross income of such individual if the individual's
"modified adjusted gross income" (which includes exempt-interest dividends) plus
one-half of the Social Security benefits or railroad retirement benefits
received by such individual during that taxable year exceeds the base amount
described in Section 86 of the Code.

     Entities or persons who are "substantial users" (or persons related to
"substantial users") of facilities financed by industrial development bonds or
private activity bonds should consult their tax advisors before purchasing
shares of the Municipal Bond Portfolio or the Municipal Money Market Portfolio.
"Substantial user" is defined generally for these purposes as including a "non-
exempt person" who regularly uses in trade or business a part of a facility
financed from the proceeds of such bonds.

     Issuers of bonds purchased by the Municipal Bond Portfolio (or the
beneficiary of such bonds) may have made certain representations or covenants in
connection with the issuance of such bonds to satisfy certain requirements of
the Code that must be satisfied subsequent to the issuance of such bonds.
Investors should be aware that exempt-interest dividends derived from such bonds
may become subject to federal income taxation retroactively to the date thereof
if such representations are determined to have been inaccurate or if the issuer
of such bonds (or the beneficiary of such bonds) fails to comply with such
covenants.


                                       29
<PAGE> 

           SPECIAL TAX CONSIDERATIONS RELATING TO FOREIGN INVESTMENTS

     Gains or losses attributable to foreign currency contracts, or to
fluctuations in exchange rates that occur between  the time a Portfolio accrues
interest or other receivables or accrues expenses or other liabilities
denominated in a foreign currency and the time the Portfolio actually collects
such receivables or pays such liabilities are treated as ordinary income or
ordinary loss to the Portfolio.  Similarly, gains or losses on disposition of
debt securities denominated in a foreign currency attributable to fluctuations
in the value of the foreign currency between the date of acquisition of the
security and the date of disposition also are treated as ordinary gain or loss
to the Portfolio.  These gains or losses increase or decrease the amount of a
Portfolio's net investment income available to be distributed to its
shareholders as ordinary income.

     It is expected that each Portfolio will be subject to foreign withholding
taxes with respect to its dividend and interest income from foreign countries,
and a Portfolio may be subject to foreign income taxes with respect to other
income.  So long as more than 50% in value of a Portfolio's total assets at the
close of the taxable year consists of stock or securities of foreign
corporations, the Portfolio may elect to treat certain foreign income taxes
imposed on it for United States federal income tax purposes as paid directly by
its shareholders.  A Portfolio will make such an election only if it deems it to
be in the best interest of its shareholders and will notify shareholders in
writing each year if it makes an election and of the amount of foreign income
taxes, if any, to be treated as paid by the shareholders.  If a Portfolio makes
the election, shareholders will be required to include in income their
proportionate shares of the amount of foreign income taxes treated as imposed on
the Portfolio and will be entitled to claim either a credit (subject to the
limitations discussed below) or, if they itemize deductions, a deduction, for
their shares of the foreign income taxes in computing their federal income tax
liability.

     Shareholders who choose to utilize a credit (rather than a deduction) for
foreign taxes will be subject to a number of complex limitations regarding the
availability and utilization of the credit.  Because of these limitations,
shareholders may be unable to claim a credit for the full amount of their
proportionate shares of the foreign income taxes paid by a Portfolio.
Shareholders are urged to consult their tax advisors regarding the application
of these rules to their particular circumstances.

                         TAXES AND FOREIGN SHAREHOLDERS

     Taxation of a shareholder who, as to the United States, is a nonresident
alien individual, a foreign trust or estate, a foreign corporation, or a foreign
partnership ("Foreign Shareholder") depends on whether the income from the
Portfolio is "effectively connected" with a U.S. trade or business carried on by
such shareholder.

     If the income from the Portfolio is not effectively connected with a U.S.
trade or business carried on by a Foreign Shareholder, distributions of net
investment income plus the excess of net  short-term capital gains over net
long-term capital losses will be subject to U.S. withholding tax at the rate of
30% (or such lower treaty rate as may be applicable) upon the gross amount of
the dividend.  Furthermore, Foreign Shareholders will generally be exempt from
U.S. federal income tax on gains realized on the sale of shares of the
Portfolio, distributions of net long-term capital gains, and amounts retained by
the Fund which are designated as undistributed capital gains.

     If the income from the Portfolio is effectively connected with a U.S. trade
or business carried on by a Foreign Shareholder, then distributions from the
Portfolio and any gains realized upon the sale of shares of the Portfolio, will
be subject to U.S. federal income tax at the rates applicable to U.S. citizens
and residents or domestic corporations.



                                       30
<PAGE> 

     The Portfolio may be required to withhold U.S. federal income tax on
distributions that are otherwise exempt from withholding tax (or taxable at a
reduced treaty rate) unless the Foreign Shareholder complies with Internal
Revenue Service certification requirements.

     The tax consequences to a Foreign Shareholder entitled to claim the
benefits of an applicable tax treaty may differ from those described here.
Furthermore, Foreign Shareholders are strongly urged to consult their own tax
advisors with respect to the particular tax consequences to them of an
investment in a Portfolio, including the potential application of the provisions
of the Foreign Investment in Real Estate Property Tax Act of 1980, as amended.

                               PURCHASE OF SHARES
   
     The purchase price of the Class A shares of each Portfolio of the Fund, 
except the Money Market and Municipal Money Market Portfolios, and the Class 
B shares of each Multiclass Portfolio of the Fund is the net asset value next 
determined after the order is received.  The International Small Cap 
Portfolio may impose a 1% transaction fee on share purchases. For each 
Portfolio of the Fund other then the Money Market or Municipal Money Market 
Portfolios, an order received prior to the regular close of the New York 
Stock Exchange (the "NYSE") will be executed at the price computed on the 
date of receipt; and an order received after the regular close of the NYSE 
will be executed at the price computed on the next day the NYSE is open as 
long as the Fund's transfer agent receives payment by check or in Federal 
Funds prior to the regular close of the NYSE on such day.  Shares of the 
Money Market and Municipal Money Market Portfolios may be purchased at the 
net asset value per share at the price next determined after Federal Funds 
are available to such Portfolios.  Shares of the Fund may be purchased on any 
day the NYSE is open.  The NYSE will be closed on the following days:  New 
Year's Day, Presidents' Day, Good Friday, Memorial Day, Independence Day, 
Labor Day, Thanksgiving Day and Christmas Day.
    
     Each Portfolio reserves the right in its sole discretion (i) to suspend
the offering of its shares, (ii) to reject purchase orders when in the
judgment of management such rejection is in the best interest of the Fund,
and (iii) to reduce or waive the minimum for initial and subsequent
investments for certain fiduciary accounts such as employee benefit plans or
under circumstances where certain economies can be achieved in sales of a
Portfolio's shares.  The International Equity Portfolio is currently limiting
investments in the Portfolio to: (i) reinvested dividends and distributions
by existing shareholders of the Portfolio; (ii) additional investments by
existing shareholders of the Portfolio; (iii) investments by certain
employees of Morgan Stanley; and (iv) investors who were in the process of
becoming shareholders of the Portfolio at the time the Portfolio limited
further investments.

                              REDEMPTION OF SHARES

     Each Portfolio may suspend redemption privileges or postpone the date of
payment (i) during any period that the NYSE is closed, or trading on the NYSE is
restricted as determined by the Commission, (ii) during any period when an
emergency exists as defined by the rules of the Commission as a result of which
it is not reasonably practicable for a Portfolio to dispose of securities owned
by it, or fairly to determine the value of its assets, and (iii) for such other
periods as the Commission may permit.

     No charge is made by any Portfolio for redemptions except for the 1%
transaction fee that may be assessed upon redemption of the International
Small Cap Portfolio.  Any redemption may be more or less than the
shareholder's cost depending on the market value of the securities held by
the Portfolio.



                                       31
<PAGE> 

     To protect your account and the Fund from fraud, signature guarantees are
required for certain redemptions.  Signature guarantees enable the Fund to
verify the identity of the person who has authorized a redemption from your
account.  Signature guarantees are required in connection with:  (1) all
redemptions, regardless of the amount involved, when the proceeds are to be paid
to someone other than the registered owner(s) and/or registered address; and
(2) share transfer requests.

     A guarantor must be a bank, a trust company, a member firm of a domestic
stock exchange, or a foreign branch of any of the foregoing.  Notaries public
are not acceptable guarantors.

     The signature guarantees must appear either:  (1) on the written request
for redemption; (2) on a separate instrument for assignment ("stock power")
which should specify the total number of shares to be redeemed; or (3) on all
stock certificates tendered for redemption and, if shares held by the Fund are
also being redeemed, on the letter or stock power.

                              SHAREHOLDER SERVICES

EXCHANGE FEATURES

     Shares of each Portfolio of the Fund may be exchanged for shares of any
other available Portfolio (other than the International Equity Portfolio, which
is closed to new investors).  In exchanging for shares of a Portfolio with more
than one class, the class of shares a shareholder receives in exchange will be
determined in the same manner as any other purchase of shares and will not be
based on the class of shares surrendered for the exchange.  Consequently, the
same minimum initial investment and minimum account size for determining the
class of shares received in the exchange will apply.

     Any such exchange will be based on the respective net asset values of
the shares involved.  There is no sales commission or sales charge of any
kind.  Before making an exchange, a shareholder should consider the
investment objectives of the Portfolio to be purchased.

     Exchange requests may be made either by mail or telephone.  Exchange
requests by mail should be sent to Morgan Stanley Institutional Fund, Inc., P.O.
Box 2798, Boston, Massachusetts 02208-2798. Telephone exchanges will be accepted
only if the certificates for the shares to be exchanged are held by the Fund for
the account of the shareholder and the registration of the two accounts will be
identical.  Requests for exchanges received prior to 10:00 a.m. (Eastern Time)
for the Municipal Money Market Portfolio, 11:00 a.m. (Eastern Time) for the
Money Market Portfolio, and 4:00 p.m. (Eastern Time) for the remaining
Portfolios will be processed as of the close of business on the same day.
Requests received after these times will be processed on the next business day.
Exchanges may be subject to limitations as to amounts or frequency, and to other
restrictions established by the Board of Directors to assure that such exchanges
do not disadvantage the Fund and its shareholders.

     For federal income tax purposes an exchange between Portfolios is a taxable
event for shareholders subject to tax, and, accordingly, a gain or loss may be
realized.  The exchange privilege may be modified or terminated by the Fund at
any time upon 60-days notice to shareholders.

TRANSFER OF SHARES
   
     Shareholders may transfer shares of the Fund's Portfolios to another person
by making a written request to the Fund.  The request should clearly identify
the account and number of shares to be transferred, and include the signature of
all registered owners and all stock certificates, if any, which are subject to
the transfer.  The signature on the letter of request, the stock certificate or
any stock power must be guaranteed in the same manner as described under
"Redemption of Shares".  As in the case of redemptions, the written request must
be received in good order before any transfer can be made.  Transferring shares
may affect the eligibility of an account for a given class of the Portfolio's
shares and may result in involuntary conversion or redemption of such shares.
    

                                       32
<PAGE> 

                             INVESTMENT LIMITATIONS

     Each current Portfolio has adopted the following restrictions which are
fundamental policies and may not be changed without the approval of the lesser
of:  (1) at least 67% of the voting securities of the Portfolio present at a
meeting if the holders of more than 50% of the outstanding voting securities of
the Portfolio are present or represented by proxy, or (2) more than 50% of the
outstanding voting securities of the Portfolio.  Each Portfolio of the Fund will
not:

     (1)  purchase or sell physical commodities unless acquired as a result of
ownership of securities or other instruments (except this shall not prevent the
Portfolio from purchasing or selling options or futures contracts or from
investing in securities or other instruments backed by physical commodities),
and except that the Gold Portfolio may invest in gold bullion in accordance with
its investment objectives and policies;

     (2)  purchase or sell real estate, although it may purchase and sell
securities of companies that deal in real estate and may purchase and sell
securities that are secured by interests in real estate;

     (3)  lend any security or make any other loan if, as a result, more than
33 1/3% of its total assets would be lent to other parties, but this limitation
does not apply to purchases of debt securities or repurchase agreements;

     (4)  except with respect to the Global Fixed Income, Emerging Markets,
Emerging Markets Debt, China Growth, Latin American, MicroCap, Aggressive
Equity, U.S. Real Estate Portfolios (i) purchase more than 10% of any class of
the outstanding voting securities of any issuer and (ii) purchase securities of
an issuer (except obligations of the U.S. Government and its agencies and
instrumentalities) if as a result, with respect to 75% of its total assets, more
than 5% of the Portfolio's total assets, at market value, would be invested in
the securities of such issuer;

     (5)  issue senior securities and will not borrow, except from banks and as
a temporary measure for extraordinary or emergency purposes and then, in no
event, in excess of 33 1/3% of its total assets (including the amount borrowed)
less liabilities (other than borrowings), except that each of the Emerging
Markets Debt and Latin American Portfolios may borrow from banks and other
entities in amount not in excess of 33 1/3% of its total assets (including the
amount borrowed) less liabilities in accordance with its investment objectives
and policies;

     (6)  underwrite securities issued by others, except to the extent that the
Portfolio may be considered an underwriter within the meaning of the 1933 Act in
the disposition of restricted securities;

     (7)  acquire any securities of companies within one industry if, as a
result of such acquisition, more than 25% of the value of the Portfolio's
total assets would be invested in securities of companies within such
industry; provided, however, that there shall be no limitation on the
purchase of obligations issued or guaranteed by the U.S. Government, its
agencies or instrumentalities, or (in the case of the Money Market Portfolio
or the Municipal Money Market Portfolio) instruments issued by U.S. Banks,
except that (i) the Latin American Portfolio may invest more than 25% of its
total assets in companies involved in the telecommunications industry or
financial services industry, (ii) the Gold Portfolio may invest more than 25%
of its total assets in securities of companies in the group of industries
involved in gold-related or precious-metals-related activities, as described
in the prospectus, and may invest more than 25% of its total assets in one or
more of the industries, such as mining, that are part of such group of
industries, as described in the prospectus, and (iii) the U.S. Real Estate
Portfolio may invest more than 25% of its total assets in the U.S. real
estate industry, respectively, as provided in their respective Prospectuses;
and


                                       33
<PAGE> 

     (8)  write or acquire options or interests in oil, gas or other mineral
exploration or development programs.

     In addition, each current Portfolio of the Fund has adopted non-fundamental
investment limitations as stated below and in their respective Prospectuses.
Such limitations may be changed without shareholder approval.  Each current
Portfolio of the Fund will not:
   
     (1)  purchase on margin or sell short, except (i) that the Emerging 
Markets Debt, Latin American and Aggressive Equity Portfolios may from time 
to time sell securities short without limitation but consistent with 
applicable legal requirements as stated in its Prospectus, (ii) that each of 
the Active Country Allocation, Balanced, Value Equity, Small Cap Value 
Equity, Latin American, U.S. Real Estate, International Magnum, Emerging 
Markets, Emerging Markets Debt, Equity Growth, Gold, China 
Growth and Aggressive Equity Portfolios may enter into option transactions to 
the extent that not more than 5% of the Portfolio's total assets are required 
as deposits to secure obligations under options and not more than 20% of its 
total assets are invested in options, futures contracts and options on 
futures contracts at any time, and (iii) as specified above in Fundamental 
Restriction No. (1);
    
     (2)  purchase or retain securities of an issuer if those Officers and
Directors of the Fund or its investment adviser owning more than 1/2 of 1% of
such securities together own more than 5% of such securities;

     (3)  pledge, mortgage, or hypothecate any of its assets to an extent
greater than 10% of its total assets at fair market value;

     (4)  invest for the purpose of exercising control over management of any
company;

     (5)  invest its assets in securities of any investment company, except
as permitted by the 1940 Act or the rules, regulations, interpretations or
orders of the SEC and its staff thereunder;

     (6)  except for the U.S. Real Estate Portfolio, invest in real estate
limited partnership interests, and the U.S. Real Estate Portfolio may not invest
in such interests that are not publicly traded;

     (7)  make loans except (i) by purchasing bonds, debentures or similar
obligations (including repurchase agreements, subject to the limitations as
described in the respective Prospectuses) that are publicly distributed, and
(ii) by lending its portfolio securities to banks, brokers, dealers and other
financial institutions so long as such loans are not inconsistent with the 1940
Act or the Rules and Regulations or interpretations of the Commission
thereunder;
   
     (8)  purchase puts, calls, straddles, spreads and any combination 
thereof if for any reason thereof the value of its aggregate investment in 
such classes of securities will exceed 5% of their respective total assets, 
except that: (i) each of the Active Country Allocation, Equity Growth, Gold, 
China Growth and Aggressive Equity Portfolios may enter into option 
transactions to the extent that not more than 5% of the Portfolio's total 
assets are required as deposits to secure obligations under options and not 
more than 20% of its total assets are invested in options, futures contracts 
and options on futures contracts at any time; and (ii) the Fixed Income and 
Global Fixed Income Portfolios are not subject to this limitation number (8);

    
     (9)  borrow money, except from banks for extraordinary or emergency 
purposes, and then only in amounts up to 10% of the value of the Portfolio's 
total assets, taken at cost at the time of borrowing, or purchase securities 
while borrowings exceed 5% of its total assets, except that the Latin American
and Emerging Markets Debt Portfolios may borrow in accordance with Fundamental
Restriction No. (5) above;

     (10) invest in fixed time deposits with a duration of over seven 
calendar days or invest in fixed time deposits with a duration of from two 
business days to seven calendar days if more than 10% of the Portfolio's 
total assets would be invested in these deposits.


     The Balanced, Fixed Income and Value Equity Portfolios will only issue
shares for securities or assets other than cash in a bona fide reorganization,
statutory merger, or in other acquisitions of portfolio securities (except for
municipal debt securities issued by state political subdivisions or their
agencies or instrumentalities) which (i) meet their respective investment
objectives; and (ii) are acquired for investment and not for resale.



                                       34
<PAGE>

     Each of the Global Fixed Income, Emerging Markets, Emerging Markets Debt,
China Growth, Latin American, Aggressive Equity and U.S. Real Estate Portfolios
will diversify its holdings so that, at the close of each quarter of its taxable
year, (i) at least 50% of the market value of the Portfolio's total assets is
represented by cash (including cash items and receivables), U.S. Government
securities, and other securities, with such other securities limited, in respect
of any one issuer, for purposes of this calculation to an amount not greater
than 5% of the value of the Portfolio's  total assets and 10% of the outstanding
voting securities of such issuer; and (ii) not more than 25% of the value of its
total assets is invested in the securities of any one issuer (other than U.S.
Government securities).

     With respect to Fundamental Restriction No. (7), the Fund will determine 
industry concentration in accordance with the classifications of industries 
based on the Industry Numbers from the Standard Industrial Classification 
Manual as prepared by the Office of Management and Budget, except that, with 
respect to the Money Market and Municipal Money Market Portfolios, (i) 
financial service companies will be classified according to the end users of 
their services, for example, automobile finance, bank finance and diversified 
finance will each be considered a separate industry; and (ii) asset-backed 
securities will be classified according to the underlying assets securing 
such securities.

     In accordance with Fundamental Restriction No. (7), the Latin American 
Portfolio will only invest more than 25% of its total assets in companies 
involved in the telecommunications industry or financial services industry if 
the Board of Directors determines that the Latin American markets are 
dominated by securities of issuers in such industries and that, in light of
the anticipated return, investment quality, availability and liquidity of the 
issuers in such industries, the Portfolio's ability to achieve its investment 
objective would, in light of the investment policies and limitations, be 
materially adversely affected if the Portfolio was not able to invest greater 
than 25% of its total assets in such industries.

     The percentage limitations contained in these restrictions apply at the
time of purchase of securities.  Future Portfolios of the Fund may adopt
different limitations.

                  DETERMINING MATURITIES OF CERTAIN INSTRUMENTS

     Generally, the maturity of a portfolio instrument shall be deemed to be
the period remaining until the date noted on the face of the instrument as
the date on which the principal amount must be paid, or in the case of an
instrument called for redemption, the date on which the redemption payment
must be made. However, instruments having variable or floating interest rates
or demand features may be deemed to have remaining maturities as follows:
(1) a Government Obligation with a variable rate of interest readjusted no
less frequently than annually may be deemed to have a maturity equal to the
period remaining until the next readjustment of the interest rate; (b) an
instrument with a variable rate of interest, the principal amount of which is
scheduled on the face of the instrument to be paid in one year or less, may
be deemed to have a maturity equal to the period remaining until the next
readjustment of the interest rate; (c) an instrument with a variable rate of
interest that is subject to a demand feature may be deemed to have a maturity
equal to the longer of the period remaining until the next readjustment of
the interest rate or the period remaining until the principal amount can be
recovered through demand; (d) an instrument with a floating rate of interest
that is subject to a demand feature may be deemed to have a maturity equal to
the period remaining until the principal amount can be recovered through
demand; and (e) a repurchase agreement may be deemed to have a maturity equal
to the period remaining until the date on which the repurchase of the
underlying securities is scheduled to occur, or where no date is specified,
but the agreement is subject to demand, the notice period applicable to a
demand for the repurchase of the securities.

                             MANAGEMENT OF THE FUND

OFFICERS AND DIRECTORS
   
     The Fund's officers, under the supervision of the Board of Directors, 
manage the day-to-day operations of the Fund.  The Directors set broad 
policies for the Fund and choose its officers.  Two Directors and all of the 
officers of the Fund are directors, officers or employees of the Fund's 
adviser, distributor or administrative services provider.  Directors and 
officers of the Fund are also directors and officers of some or all of the 
other investment companies managed, administered, advised or distributed by 
MSAM or its affiliates.  The other Directors have no affiliation with 
the Fund's adviser, distributor or administrative services provider.  A list 
of the Directors and officers of the Fund and a brief statement of their 
present positions and principal occupations during the past five years is set 
forth below:
    
                                       35
<PAGE> 



Name, Address              Position        Principal Occupation During
and Date of Birth          with Fund              Past Five Years
- -------------------        ---------       ---------------------------

Barton M. Biggs*          Chairman and     Chairman and Director of Morgan
1221 Avenue of the        Director         Stanley Asset Management Inc. and
Americas                                   Morgan Stanley Asset Management
New York, NY 10020                         Limited; Managing Director of Morgan
11/26/32                                   Stanley & Co. Incorporated; Director
                                           of Morgan Stanley Group Inc.; Member
                                           of International Advisory Counsel of
                                           the Thailand Fund; Director of Rand
                                           McNally Company; Member of the Yale
                                           Development Board; Chairman and
                                           Director of 16 U.S. registered
                                           investment companies managed by
                                           Morgan Stanley Asset Management 
                                           Inc.

Warren J. Olsen*           Director and    Principal of Morgan Stanley & Co.
1221 Avenue of the         President       Incorporated and of Morgan Stanley
Americas                                   Asset Management Inc.; President and
New York, NY 10020                         Director of 16 U.S. registered
12/21/56                                   investment companies managed by
                                           Morgan Stanley Asset Management 
                                           Inc. 

John D. Barrett, II        Director        Chairman and Director of Barrett
521 Fifth Avenue                           Associates, Inc. (investment
New York, NY 10135                         counseling); Director of the Ashforth
8/21/35                                    Company (real estate); Director of
                                           the Morgan Stanley Fund, Inc., PCS 
                                           Cash Fund, Inc. and Morgan Stanley 
                                           Universal Funds, Inc.




                                       36
<PAGE> 


Name, Address              Position        Principal Occupation During
and Date of Birth          with Fund              Past Five Years
- -------------------        ---------       ---------------------------

Gerard E. Jones            Director        Partner in Richards & O'Neil LLP (law
43 Arch Street                             firm); Director of the Morgan Stanley
Greenwich, CT 06830                        Fund, Inc., PCS Cash Fund, Inc. and 
1/23/37                                    Morgan Stanley Universal Funds, Inc.

Andrew McNally IV          Director        Chairman and Chief Executive Officer
8255 North Central                         of Rand McNally (publication);
Park Avenue                                Director of Allendale Insurance Co.,
Skokie, IL 60076                           Mercury Finance (consumer finance);
11/11/39                                   Zenith Electronics, Hubbell, Inc.
                                           (industrial electronics); Director of
                                           the Morgan Stanley Fund, Inc., PCS
                                           Cash Fund, Inc. and Morgan Stanley 
                                           Universal Funds, Inc.

Samuel T. Reeves           Director        Chairman of the Board and CEO,
8211 North                                 Pinacle L.L.C. (investment firm);
Fresno Street                              Director, Pacific Gas and Electric
Fresno, CA 93720                           and PG&E Enterprises (utilities);
7/28/34                                    Director of the Morgan Stanley Fund,
                                           Inc., PCS Cash Fund, Inc. and Morgan
                                           Stanley Universal Funds, Inc.

Fergus Reid                Director        Chairman and Chief Executive Officer
85 Charles Colman Blvd                     of LumeLite Corporation (injection
Pawling, NY 12564                          molding firm); Trustee and Director
8/12/32                                    of Vista Mutual Fund Group; Director
                                           of the Morgan Stanley Fund, Inc., 
                                           PCS Cash Fund, Inc. and Morgan 
                                           Stanley Universal Funds, Inc.
   
Frederick O. Robertshaw    Director        Of Counsel, Copple, Chamberlin
2800 North Central Avenue                  Boehm, P.C.; Formerly of Counsel,
Phoenix, AZ 85004                          Bryan, Cave LLP; (law firms);
1/24/34                                    Director of the Morgan Stanley Fund,
                                           Inc., PCS Cash Fund, Inc. and 
                                           Morgan Stanley Universal Funds, Inc.
    


                                       37
<PAGE> 


Name, Address              Position        Principal Occupation During
and Date of Birth          with Fund              Past Five Years
- -------------------        ---------       ---------------------------

James W. Grisham*          Vice President  Principal of Morgan Stanley & Co.
1221 Avenue of the                         Incorporated and of Morgan Stanley
Americas                                   Asset Management Inc.; Vice President
New York, NY 10020                         of 16 U.S. registered investment
10/24/41                                   companies managed by Morgan Stanley
                                           Asset Management Inc.

Michael F. Klein*          Vice President  Principal of Morgan Stanley Asset
1221 Avenue of the                         Management Inc; Officer of various
Americas                                   investment companies managed by
New York, NY 10020                         Morgan Stanley Asset Management Inc.
12/12/58                                   Previously practiced law with the New
                                           York law firm of Rogers & Wells.

Harold J. Schaaff, Jr.*    Vice President  Principal of Morgan Stanley & Co.
1221 Avenue of the                         Incorporated and of Morgan Stanley
Americas                                   Asset Management Inc.;
New York, NY 10020                         General Counsel and Secretary of
6/10/60                                    Morgan Stanley Asset Management Inc.;
                                           Vice President of 16 U.S. registered 
                                           investment companies managed by 
                                           Morgan Stanley Asset Management Inc.




                                       38
<PAGE> 


Name, Address              Position        Principal Occupation During
and Date of Birth          with Fund              Past Five Years
- -------------------        ---------       ---------------------------

Joseph P. Stadler*         Vice President  Vice President of Morgan Stanley &
1221 Avenue of the                         Co. Incorporated and Morgan Stanley
Americas                                   Asset Management Inc.; Previously
New York, NY 10020                         with Price Waterhouse LLP
6/7/54                                     (accounting); Vice President of 
                                           16 U.S. registered investment 
                                           companies managed by Morgan Stanley
                                           Asset Management Inc.

Valerie Y. Lewis*          Secretary       Vice President of Morgan Stanley &
1221 Avenue of the                         Co. Incorporated and Morgan Stanley
Americas                                   Asset Management Inc.; Previously
New York, NY 10020                         with Citicorp (banking); Secretary of
3/26/56                                    16 U.S. registered investment 
                                           companies managed by Morgan Stanley
                                           Asset Management Inc.



Karl O. Hartmann           Assistant       Senior Vice President, Secretary and
73 Tremont Street          Secretary       General Counsel of Chase Global Funds
Boston, MA 02108-3913                      Services Company; Previously, Leland,
3/7/55                                     O'Brien, Rubinstein Associates, Inc.
                                           (investments).




                                       39
<PAGE> 


Name, Address              Position        Principal Occupation During
and Date of Birth          with Fund              Past Five Years
- -------------------        ---------       ---------------------------

James R. Rooney            Treasurer       Vice President, Director of Fund 
73 Tremont Street                          Administration and Compliance
Boston, MA 02108-3913                      Services, Chase Global Funds
10/21/58                                   Services Company; Director of Fund
                                           Administration; Officer of various
                                           investment companies managed by
                                           Morgan Stanley Asset Management Inc.;
                                           Previously with Scudder, Stevens &
                                           Clark, Inc. (investments) and Ernst &
                                           Young LLP (accounting); Treasurer of
                                           16 U.S. registered investment 
                                           companies managed by Morgan Stanley
                                           Asset Management Inc.

Joanna Haigney             Assistant       Manager of Fund Administration and
73 Tremont Street          Treasurer       Compliance Services, Chase Global
Boston, MA 02108-3913                      Funds Services Company; Previously
10/10/66                                   with Coopers & Lybrand LLP; Assistant
                                           Treasurer of 16 U.S. registered 
                                           investment companies managed by 
                                           Morgan Stanley Asset Management Inc.

- --------------

*    "Interested Person" within the meaning of the 1940 Act.




                                       40
<PAGE> 

REMUNERATION OF DIRECTORS AND OFFICERS

     Effective June 28, 1995, the Open-end Fund Complex will pay each of
the nine Directors who is not an "interested person" an annual aggregate fee
of $55,000, plus out-of-pocket expenses.  The Open-end Fund Complex will pay
each of the members of the Fund's Audit Committee, which consists of the
Fund's Directors who are not "interested persons," an additional annual
aggregate fee of $10,000 for serving on such a committee.  The allocation of
such fees will be among the three funds in the Open-end Fund Complex in
direct proportion to their respective average net assets.  For the fiscal
year December 31, 1996, the Fund paid approximately $389,000 in Directors'
fees and expenses.  Directors who are also officers or affiliated persons
receive no remuneration for their services as Directors.  The Fund's officers
and employees are paid by the Adviser or its agents. As of April 7, 
1997, to Fund management's knowledge, the Directors and officers of the Fund, 
as a group, owned more than 1% of the outstanding common stock of the 
following Portfolios of the Fund: 2.0% Asian Equity Portfolio - Class A shares;
2.2% Emerging Markets Portfolio - Class B shares; 2.6% Latin American Portfolio
- - Class A shares and 2.9% Technoogy Portfolio - Class A shares.  The following
table shows aggregate compensation paid to each of the Fund's Directors by the 
Fund and the Fund Complex, respectively, in the fiscal year ended December 31, 
1996.


                               COMPENSATION TABLE

   
<TABLE>
<CAPTION>

- ----------------------------------------------------------------------------------------------------------------------------------
- ----------------------------------------------------------------------------------------------------------------------------------

     (1)                           (2)                        (3)                       (4)                      (5)
     NAME OF                       AGGREGATE                  PENSION OR                ESTIMATED                TOTAL
     PERSON,                       COMPENSATION               RETIREMENT                ANNUAL                   COMPENSATION
     POSITION                      FROM                       BENEFITS ACCRUED          BENEFITS                 FROM REGISTRANT
                                   REGISTRANT                 AS PART OF FUND           UPON                     AND FUND COMPLEX
                                                              EXPENSES                  RETIREMENT               PAID TO DIRECTORS

- ----------------------------------------------------------------------------------------------------------------------------------
- ----------------------------------------------------------------------------------------------------------------------------------
<S>                                <C>                        <C>                       <C>                      <C>
Barton M. Biggs,                         N/A                     N/A                      N/A                                 N/A
Director and Chairman
of the Board

Warren J. Olsen,                         N/A                     N/A                      N/A                                 N/A
Director and President

John D. Barrett, II                   59,485                     N/A                      N/A                               68,777
Director

Gerard E. Jones,                      59,485                     N/A                      N/A                               75,877
Director

Andrew McNally, IV                    55,023                     N/A                      N/A                               63,195
Director

Samuel T. Reeves,                     53,287                   N/A                      N/A                               61,331
Director

Fergus Reid,                          67,434                   N/A                      N/A                               77,220
Director

Frederick O. Robertshaw,              50,834                   N/A                      N/A                               58,777
Director



Frederick B. Whittemore,*               N/A                    N/A                       N/A                                N/A
Director
</TABLE>

___________

* As of March 14, 1997, Mr. Whittemore resigned from the Board of Directors.
    



                                       41
<PAGE> 

INVESTMENT ADVISORY AND ADMINISTRATIVE AGREEMENTS

     Morgan Stanley Asset Management Inc. ("MSAM" or the "Adviser") is a
wholly-owned subsidiary of Morgan Stanley Group Inc.  The principal offices
of Morgan Stanley Group Inc. are located at 1221 Avenue of the Americas, New
York, NY 10020.  As compensation for advisory services for the fiscal years
ended December 31, 1994, December 31, 1995 and December 31, 1996, the Adviser
earned fees of approximately $34,338,000, $40,534,000 and $55,465,000,
respectively, and from such fees voluntarily waived fees of $2,640,000,
$3,526,000 and $4,430,000, respectively.  For the fiscal years ended
December 31, 1994, December 31, 1995 and December 31, 1996, the Fund paid
brokerage commissions of approximately $7,287,293, $10,317,515 and
$17,014,335, respectively.  For the fiscal years ended December 31, 1994,
December 31, 1995 and December 31, 1996, the Fund paid in the aggregate
$796,000, $377,000 and $826,686, respectively, as brokerage commissions to
Morgan Stanley & Co. Incorporated, an affiliated broker-dealer, which
represented 11%, 4%, and 4% of the total amount of brokerage commissions
paid in each respective period.  For the fiscal years ended  December 31,
1994, December 31, 1995 and December 31, 1996, the Fund paid administrative
fees to MSAM of approximately $4,458,000, $5,238,000 and $7,298,531,
respectively.

     The Sub-Adviser, Sun Valley Gold Company, with principal offices at
620 Sun Valley Road, Sun Valley, Idaho, serves as the investment sub-adviser
of the Gold Portfolio, pursuant to a sub-advisory agreement among the Fund,
the Adviser and the Sub-Adviser (the "Sub-Advisory Agreement").  The Adviser
and the Sub-Adviser have entered into an indemnification agreement under
which, generally, the Sub-Adviser has agreed to indemnify the Adviser and the
Fund for claims or losses in connection with any failure by the Sub-Adviser
to comply with its obligations under the Sub-Advisory Agreement or related
agreements or any act or omission that amounts to negligence, misfeasance or
bad faith, and the Adviser has agreed to indemnify the Sub-Adviser for claims
or losses in connection with any failure by the Adviser to comply with its
obligations under the Sub-Advisory Agreement or related agreements.  As
compensation for sub-advisory services for the fiscal years ended December
31, 1994, December 31, 1995 and December 31, 1996, the Sub-Adviser earned
fees of approximately $76,000, $73,000 and $110,000, respectively, and
from such fees voluntarily waived fees of $36,000, $37,000 and $52,000,
respectively.  For the fiscal years ended December 31, 1994, December 31,
1995 and December 31, 1996, the Fund paid $8,000, $450 and $0,
respectively, as brokerage commissions to Sun Valley.

     Pursuant to the MSAM Administration Agreement between the Adviser and
the Fund, the Adviser provides Administrative Services.  For its services under
the Administration Agreement, the Fund pays the Adviser a monthly fee which on
an annual basis equals 0.15 of 1% of the average daily net assets of each
Portfolio.

     Under the Agreement between the Adviser and The Chase Manhattan Bank
("Chase"), Chase Global Funds Services Company ("CGFSC," a corporate affiliate
of Chase) provides certain administrative services to the Fund.  CGFSC provides
operational and administrative services to investment companies with 
approximately $69 billion in assets and having approximately 215,930 
shareholder accounts as of December 31, 1996.  CGFSC's 
business address is 73 Tremont Street, Boston, Massachusetts 02108-3913.



                                       42
<PAGE> 

DISTRIBUTION OF FUND SHARES

     Morgan Stanley & Co. Incorporated (the "Distributor"), a wholly-owned 
subsidiary of Morgan Stanley Group Inc., serves as the Distributor of the 
Fund's shares pursuant to a Distribution Agreement for the Fund and a Plan of 
Distribution for the Class B shares of the Portfolios (except the Money 
Market, Municipal Money Market and International Small Cap Portfolios which 
do not have Class B shares) pursuant to Rule 12b-1 under the 1940 Act (each, 
a "Plan" and collectively, the "Plans").  Under each Plan the Distributor is 
entitled to receive from these Portfolios a distribution fee, which is 
accrued daily and paid quarterly, at an annual rate of up to 0.25% of the 
average daily net assets of the Class B shares of these Portfolios.  The 
Distributor expects to allocate most of its fee to its investment 
representative and investment dealers, banks or financial service firms that 
provide distribution services ("Participating Dealer").  The actual amount of 
such compensation is agreed upon by the Fund's Board of Directors and by the 
Distributor.  The Distributor may, in its discretion, voluntarily waive from 
time to time all or any portion of its distribution fee and the Distributor 
is free to make additional payments out of its own assets to promote the sale 
of Fund shares.
   
     The Plans obligate the Portfolios to accrue and pay to the Distributor
the fee agreed to under its Distribution Agreement. The Plans do not obligate
the Portfolios to reimburse the Distributor for the actual expenses the
Distributor may incur in fulfilling its obligations under the Plans.  Thus,
under each Plan, even if the Distributor's actual expenses exceed the fee
payable to it thereunder at any given time, the Portfolios will not be obligated
to pay more than that fee. If the Distributor's actual expenses are less than
the fee it receives, the Distributor will retain the full amount of the fee. The
Plans for the Class B shares were most recently approved by the Fund's Board of
Directors, including those directors who are not "interested persons" of the
Fund as that term is defined in the 1940 Act and who have no direct or indirect
financial interest in the operation of a Plan or in any agreements related
thereto, on February 13, 1997.

     The Class B shares commenced operations on January 2, 1996. Therefore,
no Rule 12b-1 fees were paid to the Distributor for the fiscal year ended
December 31, 1995.  The Mortgage-Backed Securities, China Growth and MicroCap
Portfolios were not in operation in the fiscal year ended December 31, 1996.
    
CODE OF ETHICS

     The Board of Directors of the Fund has adopted a Code of Ethics under
Rule 17j-1 of the 1940 Act which incorporates the Code of Ethics of the Adviser
(together, the "Codes").  The Codes significantly restrict the personal
investing activities of all employees of the Adviser and, as described below,
impose additional, more onerous, restrictions on the Fund's investment
personnel.

     The Codes require that all employees of the Adviser preclear any
personal securities investment (with limited exceptions, such as government
securities).   The preclearance requirement and associated procedures are
designed to identify any substantive prohibition or limitation applicable to the
proposed investment.  The substantive restrictions applicable to all employees
of the Adviser include a ban on acquiring any securities in a "hot" initial
public offering and a prohibition from profiting on short-term trading in
securities.  In addition, no employee may purchase or sell any security that at
the time is being purchased or sold (as the case may be), or to the knowledge of
the employee is being considered for purchase or sale, by any fund advised by
the Adviser.  Furthermore, the Codes provide for trading "blackout periods" that
prohibit trading by investment personnel of the Fund within periods of trading
by the Fund in the same (or equivalent) security.


                                       43
<PAGE> 

CONTROL PERSONS AND PRINCIPAL HOLDERS OF SECURITIES
   
     The names and addresses of the holders of 5% or more of the outstanding
shares of any class of the Fund as of April 7, 1997 and the percentage of
outstanding shares of such classes owned beneficially or of record by such
shareholders as of such date are, to Fund management's knowledge, as follows:
    
   
ACTIVE COUNTRY ALLOCATION PORTFOLIO:  City of New York Deferred Compensation 
Plan, 40 Rector Street, 3rd Floor, New York, NY 10006, owned 26% of such 
Portfolio's total outstanding Class A shares.
    
The Trustees of Columbia University in the City of New York, 475 Riverside 
Drive, Suite 401, New York, NY 10115, owned 15% of such Portfolio's total 
outstanding Class A shares.

Oglebay Norton Company, 1100 Superior Avenue, Cleveland, OH 44114-2598, owned
11% of such Portfolio's total outstanding Class A shares.
   
Boatmen's Trust Co. Pension Plan, P.O. Bos 14737, St. Louis, MO 63178-4737 
owned 7% of such Portfolio's total outstanding Class A shares.
    
   
The Flinn Foundation, Northern Trust Co., Master Trust Dept., 7th Floor, P.O. 
Box 92984, Chicago, IL 60675, owned 6% of such Portfolio's total outstanding 
Class A shares.
    
   
Sahara Enterprises, Inc., 3 First National Plaza, Suite 2000, Chicago, IL 60602-
4260, owned 7% of such Portfolio's total outstanding Class A shares.
    
   
The Chase Manhattan Bank, N.A., Trustee Chubb Capital Accumulation Plan, 770
Broadway, New York, NY 10003, owned 7% of such Portfolio's total outstanding
Class A shares.
    
Fredric W. & Stephanie C. Harman, 21 Hillbrook, Portola Valley, CA 94028, 
owned 54% of such Portfolio's total outstanding Class B shares.

David M. & Sharon M. Platter, 9 Palmer Lane, Riverside, CT 06878, owned 46% of
such Portfolio's total outstanding Class B shares.
   
AGGRESSIVE EQUITY PORTFOLIO:  Ministers and Missionaries Benefit Board of the 
American Baptist Churches, Attn: Morgan Stanley Asset Management, 1221 Avenue 
of the Americas, New York, NY 10020, owned 11% of such Portfolio's total 
outstanding Class A shares.
    
Northern Trust Company Trustee, FBO Morgan Stanley Profit Sharing Plan, P.O.
Box 92956, Chicago, IL 60675-2956, owned 9% of such Portfolio's total 
outstanding Class A shares.
   
Valassis Enterprises - Equity C/O Franklin Enterprises, 520 Lake Cook Road, 
Suite 380, Deerfield, IL 60015, owned 6% of such Portfolio's total 
outstanding Class A shares.
    
   
Kinghugh S.A., C/O Morgan Stanley Asset Management, 1221 Avenue of the Americas,
New York, NY 10020, owned 6% of such Portfolio's total outstanding Class A
shares.
    
   
Bank Morgan Stanley AG, Bahnogstrasse 92, Zurich CH-8023, Switzerland owned 
6% of such Portfolio's total outstanding Class A shares.
    


                                       44
<PAGE>
   
ASIAN EQUITY PORTFOLIO:  Association De Bienfsaissance Et De Retraite Des
Pollciers De La Communaute Urbaine De Montreal, 480 Gilford Street, Montreal,
Quebec H2J1N3, owned 9% of such Portfolio's total outstanding Class A shares.
    
Northern Trust Company Trustee, FBO Morgan Stanley Profit Sharing Plan, P.O. 
Box 92956, Chicago, IL 60675-2956, owned 6% of such Portfolio's total 
outstanding Class A shares.
   
James L. & Sarah M. Barksdale, Trustees of Jim & Sally Barksdale, 800 
Woodlands Parkway, Suite 118, Ridgeland, MS 39157-5216 owned 6% of such 
Portfolio's total outstanding Class B shares.
    
   
BALANCED PORTFOLIO:  Kinney Printing Co-Employees, 4801 So. Lawndale, Chicago, 
IL 60632-3018, owned 16% of such Portfolio's total outstanding Class A shares.
    
   
H. Conrad & Sarah Meyer, One Woodland Avenue, Bronxville, NY 10708, owned 12%
of such Portfolio's total outstanding Class A shares.
    
Joan M. Hunt Trust, 8627 Madison Drive, Niles, IL 60648, owned 8% of such 
Portfolio's total outstanding Class A shares.
   
    
Guarantee & Trust Company, IRA Rollover, One Woodland Avenue, Bronxville, NY
10708, owned 7% of such Portfolio's total outstanding Class A shares.
   
William Guthrie, IRA Rollover, 435 Sheridan Road, Winnetka, IL  60093-2626,
owned 32% of such Portfolio's total outstanding Class B shares.
    
   
Ramakrishna Kothalanka M.D., Profit Sharing Plan, MSTC Custodian, 126 Bentley
Avenue, Jersey City, NJ 07304-1702, owned 16% of such Portfolio's total
outstanding Class B shares.
    
   
    
   
Sam G. Pitroda Custodian for Rajal Pitroda, 1480 Goldenbell Court, Downers 
Grove, IL 60515-1301, owned 8% of such Portfolio's total outstanding Class B 
shares.
    
   
Sam G. Pitroda Custodian for Salil Pitroda, 1480 Goldenbell Court, Downers 
Grove, IL 60515-1301, owned 8% of such Portfolio's total outstanding Class B 
shares.
    
   
Phyllis M. Mott IRA, MSTC Custodian, 120 West State Street, Suite 400, Rockford,
IL 61101, owned 8% of such Portfolio's total outstanding Class B shares.
    
EMERGING GROWTH PORTFOLIO:  Northern Trust Company Trustee, FBO Morgan Stanley
Profit Sharing Plan, P.O. Box 92956, Chicago, IL 60675-2956, owned 47% of such
Portfolio's total outstanding Class A shares.
   
Allendale Mutual Insurance Co., P.O. Box 7500, Johnston, RI 02919-0750, owned
17% of such Portfolio's total outstanding Class A shares.
    
   
NOAM/A/EC, C/O Philip Winters, Morgan Stanley Asset Management, 1221 6th Avenue,
New York, NY 10020, owned 8% of such Portfolio's total outstanding Class A 
shares.
    
South Trust Estate & Trust Company of Georgia, Trustee U/A Southern Engineering
Company Retirement Plan, P.O. Box 1001, Atlanta, GA 30301, owned 7% of such 
Portfolio's total outstanding Class A shares.
   
HVA Limited Partnership, C/O H L Van Arnem, 1301 W. Newport Center Drive, 
Deerfield Beach, FL 33442-7734, owned 11% of such Portfolio's total outstanding 
Class B shares.
    
   
Anne W. Rohrbach, c/o Gleacher Avenue, 660 Madison Avenue, 19th Floor, New 
York, NY 10021, owned 11% of such Portfolio's total outstanding Class B shares
    
   
Lawrence M. Howell, Howell Capital, One Maritime Plaza, Suite 1700, San
Francisco, CA 94101, owned 7% of such Portfolio's total outstanding Class B
shares.
    
Julian Eisner, 871 Oak Lane, North Woodmere, NY 11581, owned 7% of such 
Portfolio's total outstanding Class B shares.
   
Conrad & Sarah Meyer, One Woodland Avenue, Bronxville, NY 10708, owned 6% of
such Portfolio's total outstanding Class B shares.
    
   
Bruce S. Ives, 163 Gallows Hill Road, West Redding, CT 06896, owned 6% of 
such Portfolio's total outstanding Class B shares.
    
William B. O'Connor, 18 Montfort Road, Port Washington, NY 11050, owned 6% of 
such Portfolio's total outstanding Class B shares.

James F. & Marlene Connors, 205 E. Joppa Road, Towson, MD 21286, owned 5% of 
such Portfolio's total outstanding Class B shares.
   
    
   
EMERGING MARKETS DEBT PORTFOLIO:  Northwestern University, 633 Clark Street,
Evanston, IL 60208-1122, owned 20% of such Portfolio's total outstanding Class A
shares.
    
   
Valassis Enterprises - Equity, C/O Franklin Enterprises, 520 Lake Cook Road, 
Deerfield, IL 60015, owned 6% of such Portfolio's total outstanding Class A
shares.
    
   
Northern Trust Company Trustee, FBO Morgan Stanley Profit Sharing Plan, P.O. Box
92956, Chicago, IL 60675-2956, owned 6% of such Portfolio's total outstanding 
Class A shares.
    
   
Swarthmore College, 500 College Avenue, Swarthmore, PA 19081-1110, owned 7% of
such Portfolio's total outstanding Class A shares.
    
   
Morgan Stanley & Co. Pension Fund, C/O Northern Trust Co., 770 Broadway,
New York, NY 10003, owned 7% of such Portfolio's total outstanding
Class A shares.
    
   
Michael J. Fuchs, 9 West 57th Street, New York, NY 10019, owned 11% of such 
Portfolio's total outstanding Class B shares.
    
   
Alice H. & Paul D. Bartlett, 4800 Main Street, Kansas City, MO 64112, owned 
11% of such Portfolio's total outstanding Class B shares.
    
   
Daniel E. Winters, 1319 Mirror Terrace, NW, Winter Haven, FL 33881, owned 8% of
such Portfolio's total outstanding Class B shares.
    
Bruce A. Drummond, 1847 Onaway SE, Grand Rapids, MI 49506, owned 6% of such 
Portfolio's total outstanding Class B shares.

Eleanor S. Herkert Trustee of the Eleanor S. Herkert Trust, 2000 Diana Drive,
Lakeview West, Hallandale, FL 33009, owned 6% of such Portfolio's total 
outstanding Class B shares.
   
David Brooks Gendron, 2 Montpelier Place, London SW7 1HJ England, UK, owned 
6% of such Portfolio's total outstanding Class B shares.
    
   
Paul D. Bartlett, Jr,. 4800 Main Street, Suite 600, Kansas City, MO 64112, 
owned 5% of such Portfolio's total outstanding Class B shares.
    
   
    
EMERGING MARKETS PORTFOLIO:  Ministers & Missionaries Benefit Board of the
American Baptist Churches, 475 Riverside Drive, New York, NY 10115, owned 7% of
such Portfolio's total outstanding Class A shares.

Ewing Marion Kauffman Foundation, 4900 Oak Street, Kansas City, MO 64112, owned
7% of such Portfolio's total outstanding Class A shares.
   
    
   
EQUITY GROWTH PORTFOLIO:  Fidelity Management Trust Company as Trustee for 
GTE Master Savings Trust, 82 Devonshire Street, Boston, MA 02109, owned 25% 
of such Portfolio's total outstanding Class A shares.
    
   
Northern Trust Company Trustee, FBO Morgan Stanley Profit Sharing Plan, P.O. 
Box 92956, Chicago, IL 60675, owned 17% of such Portfolio's total outstanding 
Class A shares.
    
St. Raymonds Cemetery Reserve Fund, P.O. Box 92800, Rochester, NY 14692, owned
5% of such Portfolio's total outstanding Class A shares.
   
Fidelity Investments Institutional Operations Company, Agent for Certain 
Employee Benefit Plans, 100 Magellan Way, Covington, KY 41015, owned 8% of such 
Portfolio's total outstanding Class A shares.
    
   
Philip E. Asquith, 31 Lakeside Drive, Ramsey, NJ 07446, owned 5% of such
Portfolio's total outstanding Class B shares.
    
   
    


                                       45
<PAGE>

EUROPEAN EQUITY PORTFOLIO:  Marc Andreessen Trustees, FBO Marc Andreessen, 
16615 Lark Avenue, Los Gatos, CA 95030, owned 12% of such Portfolio's total 
outstanding Class B shares.
   
Wayne Gretzky Trustee of the Gretzky Trust of 1989, 9100 Wilshire Boulevard,
Beverly Hills, CA 90210, owned 6% of such Portfolio's total outstanding 
Class B shares.
    
Paul M. and Shirley F. Mathews, 25 West 706 Jerome Avenue, Wheaton, IL 60187,
owned 6% of such Portfolio's total outstanding Class B shares.
   
William & Brenda Castonguay, 9101 Hometown Drive, Raleigh, NC 27615, owned 5% 
of such Portfolio's total outstanding Class B shares.
    
   
FIXED INCOME PORTFOLIO:  Northern Trust Company Trustee, FBO Morgan Stanley
Profit Sharing Plan, P.O. Box 92956, Chicago, IL 60675-2956, owned 29% of such
Portfolio's total outstanding Class A shares.
    
Brooks School, C/O Mr. Frank Marino, North Andover, MA 01845, owned 7% of such
Portfolio's total outstanding Class A shares.
   
    
   
Trust for Descendents of David R. Jaffe, C/O David Jaffe, 45 Hemlock Ridge, 
Weston, CT 06883, owned 8% of such Portfolio's total outstanding Class B 
shares.
    
   
Laverne M. Brownsey Trust UA, 135 S. LaSalle Street, Chicago, IL 60603, owned
7% of such Portfolio's total outstanding Class B shares.
    
   
First United Methodist Church of Chicago - Endowment Fund, 77 West Washington,
Chicago, IL 60602, owned 7% of such Portfolio's total outstanding Class
B shares.
    
   
Cascino Investment Co., 820 Burgess Hill, Naperville, IL 60565, owned 16% of 
such Portfolio's total outstanding Class B shares.

Marvin J. Schneider, MSTC Custodian, 12331 Ladue Road, St. Louis, MO 63141, 
owned 8% of such Portfolio's total outstanding Class B shares.

Joan M. Hunt, MSTC Custodian, 8627 Madison Drive, Niles, IL 60648, owned 7% 
of such portfolio's total outstanding Class B shares.

Michael S. Virgil, FBO Mary Ann Young Brownsey Trust, 135 S. LaSalle Street, 
Chicago, IL 60603, owned 7% of such Portfolio's total outstanding Class B 
shares.

Joan O. Benjamin, 10 Saint Lukes Place, New York, NY 10014, owned 7% of such 
Portfolio's total outstanding Class B shares.

John K. Howe, MSTC Custodian, 7274 East Las Palmaritas Drive, Scottsdale, AZ 
85258, owned 7% of such Portfolio's total outstanding Class B shares.
    
   
GLOBAL EQUITY PORTFOLIO:  Robert College of Istanbul Turkey C/O Morgan Stanley
Asset Management, 25 Cabot Square, London, England E144QA, owned 47% of such
Portfolio's total outstanding Class A shares.
    
JM Kaplan Fund, Inc., 880 Third Avenue, 3rd floor, New York, NY 10022, owned 
13% of such Portfolio's total outstanding Class A shares.


                                       46
<PAGE>

Kaplan, Choate Value Partners, L.P., 880 Third Avenue, New York, NY 10022-4730,
owned 9% of such Portfolio's total outstanding Class A shares.

Gooss & Company, C/O Chase Manhattan Bank, 1211 6th Avenue, New York, NY 10036,
owned 7% of such Portfolio's total outstanding Class A shares.

Divtex and Company FBO, Pritchard Hubble and Herr C/O Texas Commerce Bank, P.O.
Box 2558, Houston, TX 77252, owned 7% of such Portfolio's total outstanding
Class A shares.
   
Bank of Mississippi, P.O. Box 1605, Jackson, MS 39215, owned 13% of such 
Portfolio's total outstanding Class B shares.
    
   
Fidelity Investments Institutional Operations as Agent for Certain Employee 
Benefit Plans, 100 Magellan Way, Covington, KY 41015, owned 13% of such 
Portfolio's total outstanding Class B shares.
    
   
Edward J. Prostic, 2225 Stratford Road, Mission Hills, KS 66208, owned 9% of 
such Portfolio's total outstanding Class B shares.
    
   
V. Marc Droppert IRA, MSTC Custodian, 13106 184th NE, Redmond, WA 98052, owned 
8% of such Portfolio's total outstanding Class B shares.
    
   
North American Trust Company, FBO Heller/Robert S. Venning, P.O. Box 84419, San
Diego, CA  92138, owned 7% of such Portfolio's total outstanding Class B
shares.
    
   
    
   
Leslie E. Tiffany IRA, MSTC, 14312 173rd Place NE, Redmond, WA 98052, owned 6% 
of such Portfolio's total outstanding Class B shares.
    
   
GLOBAL FIXED INCOME PORTFOLIO:  Farm Credit Bank Retirement Plan, Columbia
District American Industries Trust Company Trustee, 5700 NW Central Drive, 4th
Floor, Houston, TX 77092, owned 19% of such Portfolio's total outstanding Class
A shares.
    
   
Northern Trust Company as Custodian FBO The Lund Foundation, P.O. Box 92956,
Chicago, IL 60675, owned 15% of such Portfolio's total outstanding Class A
shares.
    
   
The Northern Trust Co. FBO Christel Dehaan Trust, P.O. Box 92956, Chicago, IL
60675-2956, owned 6% of such Portfolio's total outstanding Class A shares.
    
   
Lakeview Holdings Ltd., Coutts & Co. (Bahamas) Ltd., P.O. Box N7788, West Bay 
St., Nassau Bahamas owned 5% of such Portfolio's total outstanding Class A 
shares.
    
   
    
   
David Brooks Gendron, 2 Montpelier Place, London SW7 1HJ, England, UK, owned 34%
of such Portfolio's total outstanding Class B shares.
    
   
Joan M. Hunt, MSTC Custodian, 8627 Madison Drive, Niles, IL 60648, owned 17% 
of such Portfolio's total outstanding Class B shares.
    
   
Laverne M. Brownsey Trust UA, 135 S. LaSalle Street, Chicago, IL 60603, owned 
16% of such Portfolio's total outstanding Class B shares.
    
   
George & Claudine Boutros, 11007 Branbrook, Houston, TX 77042, owned 7% of
such Portfolio's total outstanding Class B shares.
    
George N. and Susan P. Fugelsang, 17 Calhoun Drive, Greenwich, CT 06831, owned 
10% of such Portfolio's total outstanding Class B shares.

Paul E. & H. Anthony Hellmers, 4 Colonial Lane, Larchmont, NY 10538, owned 7% 
of such Portfolio's total outstanding Class B shares.

Anthony F. & Colette H. Rowland, C/O Cambrian Management, 1114 Avenue of the 
Americas, New York, NY 10036, owned 6% of such Portfolio's total outstanding 
Class B shares.
   
    
GOLD PORTFOLIO:  William H. Ellis Trustee, Living Trust, Attn: Julie J. Laux,
2519 N. Bosworth, Chicago, IL 60614, owned 6% of such Portfolio's total 
outstanding Class A shares.

                                       47
<PAGE>

Marshall & Ilsley Trust Company, C/F John Morey, 1000 N. Water Street, 
Milwaukee, WI 53202, owned 26% of such Portfolio's total outstanding 
Class B shares.

Barlett and Company, Profit Sharing Plan and Trust, 4800 Main Street, Kansas
City, MO 64112, owned 20% of such Portfolio's total outstanding Class B shares.

Chicago Methodist Episcopal Church Aid Society, C/O Gordon Worley, 4401 Gulf
Shore Boulevard North, Monaco Beach Club, Naples, FL 33940, owned 18% of such 
Portfolio's total outstanding Class B shares.

Steven C. Olson, 505 Knollwood Road, Ridgewood, NJ 07450, owned 16% of such
Portfolio's total outstanding Class B shares.

Priscilla & John Privat, Community Property, 8852 N.E. 24th Street, Bellevue,
WA 98004, owned 6% of such Portfolio's total outstanding Class B shares.
   
HIGH YIELD PORTFOLIO:  Northern Trust Company Trustee, FBO Morgan Stanley Profit
Sharing Plan, P.O. Box 92956, Chicago, IL 60675-2956, owned 21% of such
Portfolio's total outstanding Class A shares.
    
   
Valassis Enterprises - Equity, c/o Franklin Enterprises, 520 Lake Cook Road,
Suite 380, Deerfield, IL 60015, owned 12% of such Portfolio's total outstanding
Class A shares.
    
Adeliade L. Hinckley, C/O Jim Bell, Morgan Stanley/IIS Department, 1251 Avenue 
of the Americas, New York, NY 10020, owned 7% of such Portfolio's total 
outstanding Class B shares.
   
    
   
INTERNATIONAL EQUITY PORTFOLID: Ramakrishna Kothalanka M.D., IRA Rollover, MSTC
Custodian, 126 Bentley Avenue, Jersey City, NJ 07304, owned 5% of such 
Portfolio's total outstanding Class B shares.
    
   
Fleet Bank, Trustee for Third Presbyterian Church, P.O. Box 92800, Rochester, 
NY 14692, owned 17% of such Portfolio's total outstanding Class B shares.
    
   
INTERNATIONAL MAGNUM PORTFOLIO:  Bankers Trust Trustee, Harris Corporation 
Retirement Plan & Harris Corporation Union Retirement Plan, 1025 W. Nasa 
Boulevard, Melbourne, FL 32919, owned 47% of such Portfolio's total outstanding
Class A shares.
    
   
    


                                       48
<PAGE>

   
Southwest Guaranty Trust Co., 2121 Sage Road, Suite 150, Houston, TX 77056, 
owned 6% of such Portfolio's total outstanding Class A shares.
    
   
Fidelity Investments Institutional Operations Company, Agent for Certain 
Employee Benefit Plans, 100 Magellan Way, Covington, KY 41015, owned 83% 
of such Portfolio's total outstanding Class B shares.
    
INTERNATIONAL SMALL CAP PORTFOLIO:  The Short Brothers Pension Fund, P.O. Box
241, Airport Road, Belfast, N. Ireland, owned 11% of such Portfolio's total
outstanding Class A shares.

Trustees of Boston College Attn:  Paul Haran Associate Treasurer, St. Thomas
More Hall 310, Chestnut Hill, MA 02167, owned 7% of such Portfolio's total
outstanding Class A shares.

General Mills, Inc. Master Trust:  Pooled International Fund, One General Mills
Blvd., Minneapolis, MN 55426, owned 7% of such Portfolio's total outstanding
Class A shares.
   
JAPANESE EQUITY PORTFOLIO:  United Carolina Bank Trust Operations, P.O. Box 
632, Whiteville, NC 28472, owned 23% of such Portfolio's total outstanding 
Class B shares.
    
   
Barlett and Company, Profit Sharing Plan and Trust, 4800 Main Street, Kansas
City, MO 64112, owned 14% of such Portfolio's total outstanding Class B shares.
    
Paul M. & Shirley F. Mathews, 25 W. 706 Jerome Avenue, Wheaton, IL 60187, 
owned 7% of such Portfolio's total outstanding Class B shares.
   
William & Brenda Castonguay, 9101 Hometown Drive, Raleigh, NC 27615, owned 
7% of such Portfolio's total outstanding Class B shares.
    
Wayne Gretzky Trustee of the Gretzky Trust of 1989, 9100 Wilshire Boulevard,
Beverly Hills, CA 90210, owned 6% of such Portfolio's total outstanding 
Class B shares.
   
Douglas E. Ebert, Trustee and Successor in Trust, 326 Vailwood Court, 
Bloomfield Hills, MI 48302, owned 6% of such Portfolio's total outstanding 
Class B shares.
    
   
LATIN AMERICAN PORTFOLIO:  Investors Bank & Trust Co., Financial Product 
Services, P.O. Box 1537, Boston, MA 02205, owned 10% of such Portfolio's total
outstanding Class A shares.
    
   
    
   
MUNICIPAL BOND PORTFOLIO:  Daniel F. and Maria J. McDonald, 8550 Old
Dominion Drive, McLean, VA 22102, owned 11% of such Portfolio's total
outstanding Class A shares.
    
   
Donna Karan, C/O Stephan Weiss, The Donna Karan Company, 550 Seventh Avenue,
New York, NY 10018, owned 6% of such Portfolio's total outstanding 
Class A shares.
    
   
Frank R. Mori, 935 Park Avenue, New York, NY 10028, owned 8% of such 
Portfolio's total outstanding Class A shares.
    
Cushman Trust, C/O Cambrian Services, 1114 Avenue of the Americas, Suite 2702,
New York, NY  10036, owned 6% of such Portfolio's total outstanding Class A
shares.

Arnold E. and Jill I. Bellowe Trustees, 915 Park Lane, Montecito, CA  93108-
1421, owned 6% of such Portfolio's total outstanding Class A shares.
   
Sevenson Environmental Services, P.O. Box 396, 2749 Lockport Road, Niagra Falls,
NY 14305, owned 6% of such Portfolio's total outstanding Class A shares.
    
   
    


                                       49
<PAGE>
   
SMALL CAP VALUE EQUITY PORTFOLIO:  Valassis Enterprises - Equity, C/O Franklin 
Enterprises, 520 Lake Cook Road, Deerfield, IL 60015, owned 8% of such
Portfolio's total outstanding Class A shares.
    
McMahan Furniture Company, Attn: Richard A. McMahan, P.O. Box 8000, Carlsbad, CA
92018, owned 7% of such Portfolio's total outstanding Class A shares.

William H. Ellis Trustee, William Ellis Living Trust, 2519 N. Bosworth, 
Chicago, IL 60614, owned 5% of such Portfolio's total outstanding 
Class A shares.
   
Barlett and Company, Profit Sharing Plan and Trust, 4800 Main Street, Kansas 
City, MO 64112, owned 31% of such Portfolio's total outstanding Class B 
shares.
    
   
David Brooks Gendron, 2 Montpelier Place, London SW7 1HJ England, UK, 
owned 14% of such Portfolio's total outstanding Class B shares.
    
Robert R. Bennett IRA Rollover, MSTC Custodian, 18853 N. 88th Drive, Peoria, 
AZ 85382, owned 10% of such Portfolio's total outstanding Class B shares.

Ramakrishna Kothalanka M.D., IRA Rollover, MSTC Custodian, 126 Bentley Avenue,
Jersey City, NJ 07304, owned 9% of such Portfolio's total outstanding 
Class B shares.
   
Kinney Printing Co-Employees, Attn:  Dolores M. Miklos, 4801 South Lawndale,
Chicago, IL 60632-3018, owned 9% of such Portfolio's total outstanding Class B
shares.
    
Frank E. Hunt Trust, 8627 Madison Drive, Niles, IL 60648, owned 5% of such 
Portfolio's total outstanding Class B shares.
   
TECHNOLOGY PORTFOLIO: Goolock Associates, C/O Oppenheimer & Co. Inc., 200 
Liberty Street, New York, NY 10281, owned 21% of such Portfolio's total 
outstanding Class A shares.
    
   
Misty Investment Limited, N7776, Nassau, Bahamas, owned 10% of such 
Portfolio's total outstanding Class A shares.
    
   
Peter Karmanos Jr., 4740 Dow Ridge, Orchard Lake, MI 48324, owned 10% of 
such Portfolio's total outstanding Class A shares.
    
   
Robert F. Bernard, C/O Whittman-Hart, 311 S. Wacker Drive, Chicago, IL 60606,
owned 8% of such Portfolio's total outstanding Class A shares.
    
   
John Montelione, 619 Tremont Street, Sarasota, FL 34242, owned 6% of such 
Portfolio's total outstanding Class A shares.
    
   
Trefoil Inc., 179 St. Paul Avenue, Brantford Ontario, Canada N3T4G5, 
owned 5% of such Portfolio's total outstanding Class A shares.
    
   
William J. Connolly, 63 Blackhawk Club Court, Danville, CA 94506, owned 5% 
of such Portfolio's total outstanding Class A shares.
    
   
    
Brian E. Bellows, 6133 Pasadena Point Boulevard, Gulfport, FL 33707,
owned 18% of such Portfolio's total outstanding Class B shares.

Robert J. Weinstein M.D., & Lois Weinstein, 875 N. Michigan Avenue, Chicago, IL
60611, owned 8% of such Portfolio's total outstanding Class B shares.

Paul Krieger, 23 Fairview Avenue, Great Neck, NY 11023, owned 7% of such 
Portfolio's total outstanding Class B shares.
   
U.S. REAL ESTATE PORTFOLIO:  European Patent Organization Pension Reserve Fund,
Erhardt Strasse 27, Munich, 80331 Germany, owned 7% of such Portfolio's total
outstanding Class A shares.
    
   
Morgan Stanley & Co. Pension Fund, C/O Northern Trust Company Cust, 770
Broadway, New York, NY  10003, owned 8% of such Portfolio's total outstanding
Class A shares.
    
Northwestern University, Attn: Investment Department, 633 Clark Street, 
Evanston, IL 60208, owned 10% of such Portfolio's total outstanding Class A 
shares.

Northern Trust Company Trustee, FBO Morgan Stanley Profit Sharing Plan, P.O.
Box 92956, Chicago, IL 60675, owned 6% of such Portfolio's total outstanding 
Class A shares.
   
Charles Schwab & Co. Inc., 101 Montgomery Street, San Francisco, CA 94104, 
owned 5% of such Portfolio's total outstanding Class A Shares.
    
   
Kansas Children's Service League, P.O. Box 517, Wichita, KS 67201, owned 5%
of such Portfolio's total outstanding Class B shares.
    
   
VALUE EQUITY PORTFOLIO:  McMahan Furniture Company, Attn: Richard A. McMahan,
P.O. Box 8000, Carlsbad, CA 92018, owned 8% of such Portfolio's total 
outstanding Class A shares.
    
   
Alice H. & Paul D. Bartlett, Trustees, 4800 Main Street, Kansas City, MO 64112,
owned 19% of such Portfolio's total outstanding Class B shares.
    
   
Paul D. Bartlett Jr., 4800 Main Street, Kansas City, MO 64112, owned 13% of 
such Portfolio's total outstanding Class B shares.
    
   
Cascino Investment Co., 820 Burgess Hill, Naperville, IL 60565, onwed 11% of 
such Portfolio's total outstanding Class B shares.
    
   
David Brooks Gendron, 2 Montpelier Place, London SW7 1HJ England, UK, owned 
8% of such Portfolio's total outstanding Class B shares.
    
   
Delaware Charter Guarantee & Trust Company, C/F Nelaura O. Lewis, IRA Rollover,
78 Cedar Cliff Road, Riverside, CT 06878, owned 6% of such Portfolio's total 
outstanding Class B shares.
    
   
First United Methodist Church of Chicago - Endowment Fund, 77 West Washington,
Chicago, IL 60602, owned 6% of such Portfolio's total outstanding Class B 
shares.
    
George N. and Susan P. Fugelsang, 17 Calhoun Drive, Greenwich, CT 06831,
owned 6% of such Portfolio's total outstanding Class B shares.
   
Laverne M. Brownsey Trust, 135 S. LaSalle St., Chicago, IL 60603 owned 5% of 
such Portfolio's total outstanding Class B shares.
    


                                       50
<PAGE> 

                     NET ASSET VALUE FOR MONEY MARKET PORTFOLIOS

     The Money Market Portfolio and the Municipal Money Market Portfolio seek
to maintain a stable net asset value per share of $1.00.  These Portfolios use
the amortized cost method of valuing their securities, which does not take into
account unrealized gains or losses.  The use of amortized cost and the
maintenance of each Portfolio's per share net asset value at $1.00 is based on
the Portfolio's election to operate under the provisions of Rule 2a-7 under the
1940 Act.  As a condition of operating under that Rule, each of the Money Market
Portfolios must maintain a dollar-weighted average portfolio maturity of 90 days
or less, purchase only instruments having remaining maturities of 397 days or
less, and invest only in securities which are of "eligible quality" as
determined in accordance with regulations of the Commission.

     The Rule also requires that the Directors, as a particular
responsibility within the overall duty of care owed to shareholders,
establish procedures reasonably designed, taking into account current market
conditions and each Portfolio's investment objectives, to stabilize the net
asset value per share as computed for the purposes of sales and redemptions
at $1.00. These procedures include periodic review, as the Directors deem
appropriate and at such intervals as are reasonable in light of current
market conditions, of the relationship between the amortized cost value per
share and a net asset value per share based upon available indications of
market value.  In such review, investments for which market quotations are
readily available are valued at the most recent bid price or quoted yield
available for such securities or for securities of comparable maturity,
quality and type as obtained from one or more of the major market makers for
the securities to be valued.  Other investments and assets are valued at fair
value, as determined in good faith by the Directors.

     In the event of a deviation of over 1/2 of 1% between a Portfolio's net
asset value based upon available market quotations or market equivalents and
$1.00 per share based on amortized cost, the Directors will promptly consider
what action, if any, should be taken.  The Directors will also take such action
as they deem appropriate to eliminate or to reduce to the extent reasonably
practicable any material dilution or other unfair results which might arise from
differences between the two.  Such action may include redemption in kind,
selling instruments prior to maturity to realize capital gains or losses or to
shorten the average maturity, withholding dividends, paying distributions from
capital or capital gains or utilizing a net asset value per share as determined
by using available market quotations.

     There are various methods of valuing the assets and of paying dividends
and distributions from a money market fund.  Each of the Money Market and
Municipal Money Market Portfolios values its assets at amortized cost while also
monitoring the available market bid price, or yield equivalents.  Since
dividends from net investment income will be declared daily and paid monthly,
the net asset value per share of each Portfolio will ordinarily remain at $1.00,
but each Portfolio's daily dividends will vary in amount.  Net realized gains,
if any, will normally be declared and paid monthly.

                               PERFORMANCE INFORMATION

     The Fund may from time to time quote various performance figures to
illustrate the Portfolios' past performance.

     Performance quotations by investment companies are subject to rules
adopted by the Commission, which require the use of standardized performance
quotations.  In the case of total return, non-standardized performance
quotations may be furnished by the Fund but must be accompanied by certain
standardized performance information computed as required by the Commission.
Current yield and average annual compounded total return quotations used by the
Fund are based on the standardized methods of computing performance mandated by
the Commission.  An explanation of those and other methods used by the Fund to
compute or express performance follows.


                                       51
<PAGE> 

TOTAL RETURN

     From time to time each Portfolio, except the Money Market and Municipal
Money Market Portfolios, may advertise total return for each class of shares of
the Portfolio.  Total return figures are based on historical earnings and are
not intended to indicate future performance.  The average annual total return is
determined by finding the average annual compounded rates of return over 1-, 5-,
and 10-year periods (or over the life of the Portfolio) that would equate an
initial hypothetical $1,000 investment to its ending redeemable value.  The
calculation assumes that all dividends and distributions are reinvested when
paid.  The quotation assumes the amount was completely redeemed at the end of
each 1-, 5-, and 10-year period (or over the life of the Portfolio) and the
deduction of all applicable Fund expenses on an annual basis.
   
     The average annual compounded rates of return (unless otherwise noted)
for the Fund's Portfolios for the one year and five year periods ended
December 31, 1996 and for the period from inception through December 31, 1996
are as follows:
    
   

                             Inception   One    Average Annual   Average Annual
Name of Portfolio              Date      Year     Five Year     Since Inception
- -----------------            ---------  ------  --------------  ---------------

Active Country Allocation
Class A . . . . . . . . . .    1/17/92    9.71%        N/A            8.71%
Class B . . . . . . . . . .    1/02/96    9.22%        N/A             N/A

Aggressive Equity
Class A . . . . . . . . . .    3/08/95   40.90%        N/A           45.98%
Class B . . . . . . . . . .    1/02/96   39.72%        N/A             N/A

Asian Equity
Class A . . . . . . . . . .    7/01/91    3.49%      19.35%          18.28%
Class B . . . . . . . . . .    1/02/96    2.92%        N/A             N/A

Balanced
Class A . . . . . . . . . .    2/20/90   10.93%      10.15%          10.39%
Class B . . . . . . . . . .    1/02/96   10.24%        N/A             N/A

Emerging Growth
Class A . . . . . . . . . .   11/01/89    3.72%       4.10%          11.96%
Class B . . . . . . . . . .    1/02/96    3.58%        N/A             N/A

Emerging Markets
Class A . . . . . . . . . .    9/25/92   12.19%        N/A           12.93%
Class B . . . . . . . . . .    1/02/96   11.04%        N/A             N/A

Emerging Markets Debt
Class A . . . . . . . . . .    2/01/94   50.52%        N/A           18.94%
Class B . . . . . . . . . .    1/02/96   48.52%        N/A             N/A

Equity Growth
Class A . . . . . . . . . .    4/02/91   30.97%       16.99%         17.06%
Class B . . . . . . . . . .    1/02/96   29.92%         N/A            N/A

European Equity
Class A . . . . . . . . . .    4/02/93   22.29%         N/A          19.62%
Class B . . . . . . . . . .    1/02/96   20.76%         N/A            N/A

Fixed Income
Class A . . . . . . . . . .    5/15/91    4.61%        7.00%          8.35%
Class B . . . . . . . . . .    1/02/96    4.35%         N/A            N/A

Global Equity
Class A . . . . . . . . . .    7/15/92   22.83%         N/A          19.22%
Class B . . . . . . . . . .    1/02/96   22.04%         N/A            N/A

Global Fixed Income
Class A . . . . . . . . . .    5/01/91    6.44%        7.17%          8.50%
Class B . . . . . . . . . .    1/02/96    6.12%         N/A            N/A
    



                                       52
<PAGE> 

   

                             Inception   One    Average Annual   Average Annual
Name of Portfolio              Date      Year     Five Year     Since Inception
- -----------------            ---------  ------  --------------  ---------------

Gold
Class A . . . . . . . . . .    2/01/94   16.94%        N/A            6.80%
Class B . . . . . . . . . .    1/02/96   13.21%        N/A             N/A

High Yield
Class A . . . . . . . . . .    9/28/92   15.01%        N/A           12.91%
Class B . . . . . . . . . .    1/02/96   14.37%        N/A             N/A

International Equity
Class A . . . . . . . . . .    8/04/89   19.64%      16.41%          11.96%
Class B . . . . . . . . . .    1/02/96   18.58%        N/A             N/A

International Magnum
Class A . . . . . . . . . .    3/15/96    8.25%*       N/A             N/A
Class B . . . . . . . . . .    3/15/96    7.90%*       N/A             N/A

International Small Cap
Class A . . . . . . . . . .   12/15/92   16.82%        N/A           16.42%

Japanese Equity
Class A . . . . . . . . . .    4/25/94   -1.40%        N/A           -2.51%
Class B . . . . . . . . . .    1/02/96   -1.67%        N/A             N/A

Latin American
Class A . . . . . . . . . .    1/18/95   48.77%        N/A           16.98%
Class B . . . . . . . . . .    1/02/96   42.44%        N/A             N/A

Municipal Bond
Class A . . . . . . . . . .    1/18/95    3.67%        N/A            6.36%
Class B . . . . . . . . . .    1/02/96    3.55%        N/A             N/A

Small Cap Value Equity
Class A . . . . . . . . . .   12/17/92   22.99%        N/A           14.32%
Class B . . . . . . . . . .    1/02/96   22.33%        N/A             N/A

U.S. Real Estate
Class A . . . . . . . . . .    2/24/95   39.56%        N/A           32.73%
Class B . . . . . . . . . .    1/02/96   38.23%        N/A             N/A

Value Equity
Class A . . . . . . . . . .    1/31/90   19.73%      14.92%          12.95%
Class B . . . . . . . . . .    1/02/96   18.57%        N/A             N/A

* Cumulative (unannualized) total return since inception of the Portfolio.
    

   
    

These figures were calculated according to the following formula:

             P(1 + T)to the nth power = ERV

where:

P      =      a hypothetical initial payment of $1,000

T      =      average annual total return

n      =      number of years

ERV    =      ending redeemable value of hypothetical $1,000 payment made at
              the beginning of the 1-, 5-, or 10-year periods at the end of
              the 1-, 5-, or 10-year periods (or fractional portion thereof).

CALCULATION OF YIELD FOR NON-MONEY MARKET PORTFOLIOS

     From time to time certain of the Fund's Portfolios may advertise yield.

     Current yield reflects the income per share earned by a Portfolio's
investments.

     Current yield is determined by dividing the net investment income per
share earned during a 30-day base period by the maximum offering price per share
on the last day of the period and annualizing the result.  Expenses accrued for
the period include any fees charged to all shareholders during the base period.



                                       53
<PAGE> 
   
     The respective current yields for certain of the Fund's Portfolios for the
30-day period ended December 31, 1996 were as follows:


         PORTFOLIO NAME                       CLASS A SHARES     CLASS B SHARES
         --------------                       --------------     --------------

         Emerging Markets Debt . . . . . . .      10.46%             10.16%

         Fixed Income. . . . . . . . . . . .       6.39%              6.27%

         Global Fixed Income . . . . . . . .       4.91%              4.76%

         High Yield. . . . . . . . . . . . .       9.31%              9.05%

         Municipal Bond. . . . . . . . . . .       4.35%              4.11%
    


     These figures were obtained using the following formula:

                   Yield = 2[( a -  b + 1 )to the 6th power  - 1]
                               ------
                                 cd

     where:

     a      =    dividends and interest earned during the period
     b      =    expenses accrued for the period (net of reimbursements)
     c      =    the average daily number of shares outstanding during the
                 period that were entitled to receive income distributions
     d      =    the maximum offering price per share on the last day of the
                 period.

CALCULATION OF YIELD FOR MONEY MARKET PORTFOLIOS
   
     The current yield of the Money Market and Municipal Money Market
Portfolios is calculated daily on a base period return for a hypothetical
account having a beginning balance of one share for a particular period of
time (generally 7 days).  The return is determined by dividing the net change
(exclusive of any capital changes in such account) by its average net asset
value for the period, and then multiplying it by 365/7 to determine the
annualized current yield.  The calculation of net change reflects the value
of additional shares purchased with the dividends by the Portfolio, including
dividends on both the original share and on such additional shares.  The
yields of the Money Market and Municipal Money Market Portfolios for the
7-day period ended December 31, 1996 were 4.99% and 3.38%, respectively.  An
effective yield, which reflects the effects of compounding and represents an
annualization of the current yield with all dividends reinvested, may also be
calculated for each Portfolio by dividing the base period return by 7, adding
1 to the quotient, raising the sum to the 365th power, and subtracting 1 from
the result.  The effective yields of the Money Market and Municipal Money
Market Portfolios for the 7-day period ended December 31, 1996 were 5.11% and
3.43%, respectively.
    

     The yield of a Portfolio will fluctuate.  The annualization of a week's
dividend is not a representation by the Portfolio as to what an investment in
the Portfolio will actually yield in the future.  Actual yields will depend on
such variables as investment quality, average maturity, the type of instruments
the Portfolio invests in, changes in interest rates on instruments, changes in
the expenses of the Fund and other factors.  Yields are one basis investors may
use to analyze the Portfolios of the Fund, and other investment vehicles;
however, yields of other investment vehicles may not be comparable because of
the factors set forth in the preceding sentence, differences in the time periods
compared, and differences in the methods used in valuing portfolio instruments,
computing net asset value and calculating yield.


                                       54
<PAGE> 

TAXABLE EQUIVALENT YIELD FOR THE MUNICIPAL BOND AND MUNICIPAL MONEY MARKET
PORTFOLIO

     It is easy to calculate your own taxable equivalent yield if you know
your tax bracket.  The formula is:

                Tax Free Yield
              --------------------
              1 - Your Tax Bracket    =    Your Taxable Equivalent Yield

     For example, if you are in the 28% tax bracket and can earn a tax-free
yield of 7.5%, the taxable equivalent yield would be 10.42%.

     The table below indicates the advantages of investments in Municipal
Bonds for certain investors.  Tax-exempt rates of interest payable on a
Municipal Bond (shown at the top of each column) are equivalent to the taxable
yields set forth opposite the respective income tax levels, based on income tax
rates effective for the tax year 1996 under the Internal Revenue Code.  There
can, of course, be no guarantee that the Municipal Bond Portfolio or Municipal
Money Market Portfolio will achieve a specific yield.  Also, it is possible that
some portion of the Portfolio's dividends may be subject to Federal income
taxes. A substantial portion, if not all, of such dividends may be subject to
state and local taxes.

TAXABLE EQUIVALENT YIELD TABLE

<TABLE>
<CAPTION>

        Sample Level of                                                             Taxable Equivalent Rates
        Taxable Income                                                            Based on Tax-Exempt Yield of:
        --------------                                                            -----------------------------
                                   Federal
                                   Income
Joint            Single            Tax
Return           Return            Bracket  3%       4%        5%        6%        7%        8%        9%        10%        11%
- ------           ------            -------  --       --        --        --        --        --        --        ---        ---

<S>              <C>               <C>      <C>      <C>       <C>       <C>       <C>       <C>       <C>       <C>        <C>
$0-39,000        $0-23,350         15.0%    3.5%     4.7%      5.9%      7.1%       8.2%      9.4%     10.6%     11.8%      12.9%
39,000-94,250    23,350-56,550     28.0     4.2      5.6       6.9       8.3        9.7      11.1      12.5      13.9       15.3
94,250-143,600   56,550-117,950    31.0     4.3      5.8       7.2       8.7       10.1      11.6      13.0      14.5       15.9
143,600-256,500  117,950-256,500   36.0     4.7      6.3       7.8       9.4       10.9      12.5      14.1      15.6       17.2
over 256,500     over 256,500      39.6     5.0      6.6       8.3       9.9       11.6      13.2      14.9      16.6       18.2
</TABLE>

- -------

   
*    Net amount subject to 1996 Federal Income Tax after deductions and
     exemptions, not indexed for 1996 income tax rates.

The taxable equivalent yields for the Municipal Money Market and Municipal Bond
Portfolios for the seven days ended December 31, 1996 assuming a Federal income
tax rate of 39.6% (maximum rate), were 5.60% and 6.44%, respectively.  The
taxable equivalent effective yields for the Municipal Money Market and Municipal
Bond Portfolios for the seven days ended December 31, 1996, assuming the same
tax rate, were 5.68% and 6.57%, respectively.
    

                                       55
<PAGE> 

COMPARISONS

     To help investors better evaluate how an investment in a Portfolio of
Morgan Stanley Institutional Fund, Inc. might satisfy their investment
objective, advertisements regarding the Fund may discuss various measures of
Fund performance as reported by various financial publications.
Advertisements may also compare performance (as calculated above) to
performance as reported by other investments, indices and averages.  The
following publications may be used:

         (a)  CDA Mutual Fund Report, published by CDA Investment Technologies,
              Inc. -- analyzes price, current yield, risk, total return and
              average rate of return (average annual compounded growth rate)
              over specified time periods for the mutual fund industry.

         (b)  Financial publications:  Business Week, Changing Times, Financial
              World, Forbes, Fortune, Money, Barron's, Consumer's Digest,
              Financial Times, Global Investor, Investor's Daily, Lipper
              Analytical Services, Inc., Morningstar, Inc., New York Times,
              Personal Investor, Wall Street Journal and Weisenberger
              Investment Companies Service -- publications that rate fund
              performance over specified time periods.

         (c)  Historical data supplied by the research departments of First
              Boston Corporation, the J.P. Morgan companies, Salomon Brothers,
              Merrill Lynch, Pierce, Fenner & Smith, Lehman Brothers and
              Bloomberg L.P.

         (d)  Lipper -- Mutual Fund Performance Analysis and Lipper -- Fixed
              Income Fund Performance Analysis -- measures total return and
              average current yield for the mutual fund industry.  Ranks
              individual mutual fund performance over specified time periods,
              assuming reinvestment of all distributions, exclusive of any
              applicable sales charges.


         (e)  Mutual Fund Source Book, published by Morningstar, Inc. --
              analyzes price, yield, risk and total return for equity funds.

         (f)  Savings and Loan Historical Interest Rates -- as published in the
              U.S. Savings & Loan League Fact Book.

         (g)  Stocks, Bonds, Bills and Inflation, published by Hobson
              Associates -- historical measure of yield, price and total return
              for common and small company stock, long-term government bonds,
              U.S. Treasury bills and inflation.

The following indices and averages may also be used:

         (a)  Composite Indices -- 70% Standard & Poor's 500 Stock Index and
              30% NASDAQ Industrial Index; 35% Standard & Poor's 500 Stock
              Index and 65% Salomon Brothers High Grade Bond Index; and 65%
              Standard & Poor's 500 Stock Index and 35% Salomon Brothers High
              Grade Bond Index.

         (b)  Consumer Price Index (or cost of Living Index), published by the
              U.S. Bureau of Labor Statistics -- a statistical measure of
              change, over time, in the price of goods and services in major
              expenditure groups.

         (c)  Donoghue's Money Fund Average -- an average of all major money
              market fund yields, published weekly for 7 and 30-day yields.


                                       56
<PAGE> 

         (d)  Dow Jones Composite Average or its component averages -- an
              unmanaged index composed of 30 blue-chip industrial corporation
              stocks (Dow Jones Industrial Average), 15 utilities company
              stocks and 20 transportation stocks.  Comparisons of performance
              assume reinvestment of dividends.

         (e)  EMBI+ -- Expanding on the EMBI, which includes only Bradys, the
              EMBI+ includes a broader group of Brady Bonds, loans, Eurobonds
              and the U.S. Dollar local markets instruments.  A more
              comprehensive benchmark than the EMBI, the EMBI+ covers 49
              instruments from 14 countries.  At $96 billion, its market cap is
              nearly 50% higher than the EMBI's.  The EMBI+ is not, however,
              intended to replace the EMBI but rather to complement it.  The
              EMBI continues to represent the most liquid, most easily traded
              segment of the market, including more of the assets that
              investors typically hold in their portfolios.  Both of these
              indices are published daily.

         (f)  First Boston High Yield Index -- generally includes over 180
              issues with an average maturity range of seven to ten years with
              a minimum capitalization of $100 million.  All issues are
              individually trader-priced monthly.

         (g)  First Boston Upper/Middle Tier High Yield Index -- an unmanaged
              index of bonds rated B to BBB.

         (h)  Goldman Sachs 100 Convertible Bond Index -- currently includes 67
              bonds and 33 preferred.  The original list of names was generated
              by screening for convertible issues of 100 million or greater in
              market capitalization.  The index is priced monthly.

         (i)  IFC Global Total Return Composite Index -- an unmanaged index of
              common stocks and includes 18 developing countries in Latin
              America, East and South Asia, Europe, the Middle East and Africa
              (net of dividends reinvested).

   
         (j)  Indata Balanced-Median Index -- an unmanaged index and includes
              an asset allocation of 2.5% cash, 38.2% bonds and 59.3% equity 
              based on $52.6 billion in assets among 579 portfolios for the year
              ended December 31, 1996 (assumes dividends reinvested).

         (k)  Indata Equity-Median Stock Index -- an unmanaged index which
              includes an average asset allocation of 7.4% cash and 92.6% equity
              based on $464.9 billion in assets among 1,277 portfolios for the
              year ended December 31, 1996.
    

         (l)  J.P. Morgan Emerging Markets Bond Index -- a market-weighted
              index composed of all Brady bonds outstanding and includes
              Argentina, Brazil, Bulgaria, Mexico, Nigeria, the Philippines,
              Poland and Venezuela.
   
         (m)  J.P. Morgan Emerging Markets Bond Index Plus -- expanding on 
              the J.P. Morgan Emerging Markets Bond Index, which only trades
              Brady Bonds, this index reflects total returns for external 
              debt instruments which have been traded in emerging markets.
              Brady Bonds are included amoung such instruments, as well as 
              Eurobonds, loans and U.S. dollar denominated local market 
              instruments.  Countries included in the index are Argentina, 
              Brazil, Bulgaria, Ecuador, Mexico, Morocco, Nigeria, Panama, 
              Peru, the Phillipines, Poland, Russia, South Africa and 
              Venezuela.
    
   
         (n)  J.P. Morgan Traded Global Bond Index -- an unmanaged index of
              securities and includes Australia, Belgium, Canada, Denmark,
              France, Germany, Italy, Japan, The Netherlands, Spain, Sweden,
              United Kingdom and the United States.
    
   
         (o)  Lehman Brothers Aggregate Bond Index -- an unmanaged index made
              up of the Government/Corporate Index, the Mortgage Backed
              Securities Index and the Asset-Backed Securities Index.
    
   
         (p)  Lehman Brothers LONG-TERM Treasury Bond -- composed of all bonds
              covered by the Lehman Brothers Treasury Bond Index with
              maturities of 10 years or greater.
    


                                       57
<PAGE> 

   
         (q)  The Lehman 7 Year Municipal Bond Index -- an unmanaged index
              which consists of investment grade bonds with maturities between
              6-8 years rated BAA or better.  All bonds have been taken from
              deals done within the last 5 years, with assets of $50 million or
              larger.

         (r)  Lipper Capital Appreciation Index -- a composite of mutual funds
              managed for maximum capital gains.

         (s)  Morgan Stanley Capital International Combined Far East Free
              ex-Japan Index -- a market-capitalization weighted index
              comprising stocks in Hong Kong, Indonesia, Korea, Malaysia,
              Philippines, Singapore, Taiwan and Thailand.  Korea is included
              in the MSCI Combined Far East Free ex-Japan Index at 20% of its
              market capitalization.

         (t)  Morgan Stanley Capital International EAFE Index -- an arithmetic,
              market value-weighted average of the performance of over 900
              securities on the stock exchanges of countries in Europe,
              Australia and the Far East.

         (u)  Morgan Stanley Capital International Emerging Markets Global
              Latin America Index -- an unmanaged, arithmetic market value
              weighted average of the performance of over 196 securities on the
              stock exchanges of Argentina, Brazil, Chile, Colombia, Mexico,
              Peru and Venezuela (Assumes reinvestment of dividends).

         (v)  Morgan Stanley Capital International Europe Index -- an unmanaged
              index of common stocks and includes 14 countries throughout
              Europe.

         (w)  Morgan Stanley Capital International Japan Index -- an unmanaged
              index of common stocks.

         (x)  Morgan Stanley Capital International Latin America Index -- a
              broad-based market capitalization-weighted composite index
              covering at least 60% of markets in Mexico, Argentina, Brazil,
              Chile, Colombia, Peru and Venezuela (assumes dividends
              reinvested).

         (y)  Morgan Stanley Capital International World Index -- an
              arithmetic, market value-weighted average of the performance of
              over 1,470 securities listed on the stock exchanges of countries
              in Europe, Australia, the Far East, Canada and the United States.

         (z)  NASDAQ Composite Index -- an unmanaged index of common stocks.

         (aa) NASDAQ Industrial Index -- a capitalization-weighted index
              composed of more than 3,000 domestic stocks taken from the
              following industry sectors: agriculture, mining, construction,
              manufacturing, electronic components, services and public
              administration enterprises.  It is a value-weighted index
              calculated on price change only and does not include income.

         (bb) National Association of Real Estate Investment Trusts ("NAREIT")
              Index -- an unmanaged market weighted index of tax qualified
              REITs (excluding healthcare REITs) listed on the New York Stock
              Exchange, American Stock Exchange and the NASDAQ National Market
              System including dividends.

         (cc) The New York Stock Exchange composite or component indices --
              unmanaged indices of all industrial, utilities, transportation
              and finance company stocks listed on the New York Stock Exchange.
    


                                       58
<PAGE> 

   
         (dd) Philadelphia Gold and Silver Index -- an unmanaged index
              comprised of seven leading companies involved in the  mining of
              gold and silver.

         (ee) Russell 2000 Growth Index -- comprised of those Russell 2000 
              Securities with an above-average growth orientation. Here, 
              securities tend to exhibit higher price-to-book and 
              price-earnings ratios, lower divided yeilds and higher 
              forecasted growth than the Value universe.

         (ff) Russell 2500 Index -- comprised of the bottom 500 stocks in the
              Russell 1000 Index which represents the universe of stocks from
              which most active money managers typically select; and all the
              stocks in the Russell 2000 Index. The largest security in the
              index has a market capitalization of approximately 1.3 billion.

         (gg) Salomon Brothers GNMA Index -- includes pools of mortgages
              originated by private lenders and guaranteed by the mortgage
              pools of the Government National Association.

         (hh) Salomon Brothers High Grade Corporate Bond Index -- consists of
              publicly issued, non-convertible corporate bonds rated AA or AAA.
              It a is value-weighted, total return index, including
              approximately 800 issues with maturities of 12 years or greater.

         (ii) Salomon Brothers Broad Investment Grade Bond -- a market-weighted
              index that contains approximately 4700 individually priced
              investment grade corporate bonds rated BBB or better, U.S.
              Treasury/agency issues and mortgage pass-through securities.

         (jj) Standard & Poor's 500 Stock Index or its component indices --
              unmanaged index composed of 400 industrial stocks, 40 financial
              stocks, 40 utilities company stocks and 20 transportation stocks.
              Comparisons of performance assume reinvestment of dividends.

         (kk) Standard & Poor's Small Cap 600 Index -- a capitalization-
              weighted index of 600 domestic stocks having market
              capitalizations which reside within the 50th and the 83rd
              percentiles of the market capitalization of the entire stock
              market, chosen for certain liquidity characteristics and for
              industry representation.

         (ll) Wilshire 5000 Equity Index or its component indices -- represents
              the return on the market value of all common equity securities
              for which daily pricing is available.  Comparisons of performance
              assume reinvestment of dividends.
    
     In assessing such comparisons of performance an investor should keep in
mind that the composition of the investments in the reported indices and
averages is not identical to the composition of investments in the Fund's
Portfolios, that the averages are generally unmanaged, and that the items
included in the calculations of such averages may not be identical to the
formula used by the Fund to calculate its futures.  In addition, there can be no
assurance that the Fund will continue this performance as compared to such other
averages.

                                 GENERAL INFORMATION

DESCRIPTION OF SHARES AND VOTING RIGHTS
   
     The Fund's Articles of Incorporation, as amended and restated, permit
the Directors to issue 35 billion shares of common stock, par value $.001 per
share, from an unlimited number of classes ("Portfolios") of shares.
Currently the Fund consists of shares of twenty-nine Portfolios (the China
Growth, Mortgage-Backed Securities and MicroCap Portfolios are not currently
offering shares).
    


                                       59
<PAGE> 

     The shares of each Portfolio of the Fund are fully paid and
nonassessable, and have no preference as to conversion, exchange, dividends,
retirement or other features.  The shares of each Portfolio of the Fund have
no pre-emptive rights.  The shares of the Fund have non-cumulative voting
rights, which means that the holders of more than 50% of the shares voting
for the election of Directors can elect 100% of the Directors if they choose
to do so.  A shareholder is entitled to one vote for each full share held
(and a fractional vote for each fractional share held), then standing in his
name on the books of the Fund.


DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS

     The Fund's policy is to distribute substantially all of each Portfolio's
net investment income, if any.  The Fund may also distribute any net realized
capital gains in the amount and at the times that will avoid both income
(including taxable gains) taxes on it and the imposition of the federal excise
tax on income and capital gains (see discussion under "Taxes" in this Statement
of Additional Information).  However, the Fund may also choose to retain net
realized capital gains and pay taxes on such gains.  The amounts of any income
dividends or capital gains distributions cannot be predicted.

     Any dividend or distribution paid shortly after the purchase of shares
of a Portfolio by an investor may have the effect of reducing the per share net
asset value of that Portfolio by the per share amount of the dividend or
distribution.  Furthermore, such dividends or distributions, although in effect
a return of capital, are subject to income taxes for shareholders subject to tax
as set forth herein and in the applicable Prospectus.

     As set forth in the Prospectuses, unless the shareholder elects
otherwise in writing, all dividends and capital gains distributions for a class
of shares are automatically received in additional shares of such class of that
Portfolio of the Fund at net asset value (as of the business day following the
record date).  This automatic reinvestment of dividends and distributions will
remain in effect until the Fund is notified by the shareholder in writing at
least three days prior to the record date that either the Income Option (income
dividends in cash and capital gains distributions in additional shares at net
asset value) or the Cash Option (both income dividends and capital gains
distributions in cash) has been elected.

CUSTODY ARRANGEMENTS

     Chase is the Fund's custodian for domestic and certain foreign assets.
 Chase is not affiliated with Morgan Stanley & Co. Incorporated.
 Morgan Stanley Trust Company, Brooklyn, NY, acts as the Fund's
custodian for foreign assets held outside the United States and 
employs subcustodians who were approved by the Directors of the Fund in 
accordance with Rule 17f-5 adopted by the Commission under the 1940 Act. 
Morgan Stanley Trust Company is an affiliate of Morgan Stanley & Co. 
Incorporated.  In the selection of foreign subcustodians, the Directors 
consider a number of factors, including, but not limited to, the reliability 
and financial stability of the institution, the ability of the institution to 
provide efficiently the custodial services required for the Fund, and the 
reputation of the institution in the particular country or region.


                                       60
<PAGE> 

                            DESCRIPTION OF RATINGS

DESCRIPTION OF COMMERCIAL PAPER AND BOND RATINGS

     EXCERPTS FROM MOODY'S INVESTORS SERVICE, INC. ("MOODY'S") DESCRIPTION
OF BOND RATINGS:  Aaa - Bonds which are rated Aaa are judged to be the best
quality. They carry the smallest degree of investment risk and are generally
referred to as "gilt-edge." Interest payments are protected by a large or by
an exceptionally stable margin, and principal is secure.  While the various
protective elements are likely to change, such changes as can be visualized
are most unlikely to impair the fundamentally strong position of such issues.
 Aa -Bonds which are rated Aa are judged to be of high quality by all
standards. Together with the Aaa group they comprise what are generally known
as high grade bonds.  They are rated lower than the best bonds because
margins of protection may not be as large as in Aaa securities or fluctuation
of protective elements may be of greater amplitude or there may be other
elements present which make the long-term risks appear somewhat larger than
in Aaa securities.  Moody's applies numerical modifiers 1, 2 and 3 in the Aa
and A rating categories.  The modifier 1 indicates that the security ranks at
a higher end of the rating category, modifier 2 indicates a mid-range rating
and the modifier 3 indicates that the issue ranks at the lower end of the
rating category.  A - Bonds which are rated A possess many favorable
investment attributes and are to be considered as upper medium grade
obligations.  Factors giving security to principal and interest are
considered adequate but elements may be present which suggest a
susceptibility to impairment sometime in the future.  Baa - Bonds which are
rated Baa are considered as medium grade obligations, i.e., they are neither
highly protected nor poorly secured. Interest payments and principal security
appear adequate for the present but certain protective elements may be
lacking or may be characteristically unreliable over any great length of
time. Such bonds lack outstanding investment characteristics and in fact have
speculative characteristics as well.  Ba - Bonds which are rated Ba are
judged to have speculative elements; their future cannot be considered as
well assured. Often the protection of interest and principal payments may be
very moderate, and thereby not well safeguarded during both good and bad
times over the future. Uncertainty of position characterizes bonds in this
class.  B - Bonds which are rated B generally lack characteristics of the
desirable investment.  Assurance of interest and principal payments or of
maintenance of other terms of the contract over any long period of time may
be small.  Caa - Bonds which are rated Caa are of poor standing.  Such issues
may be in default or there may be present elements of danger with respect to
principal or interest.  Ca - Bonds which are rated Ca represent obligations
which are speculative in a high degree.  Such issues are often in default or
have other marked shortcomings. C - Bonds which are rated C are the lowest
rated class of bonds, and issues so rated can be regarded as having extremely
poor prospects of ever attaining any real investment standing.

     EXCERPTS FROM STANDARD & POOR'S RATINGS GROUP ("S&P") DESCRIPTION OF BOND
RATINGS: AAA - Bonds rated AAA have the highest rating assigned by Standard &
Poor's to a debt obligation and indicate an extremely strong capacity to pay
principal and interest.  AA - Bonds rated AA have a very strong capacity to pay
interest and repay principal and differ from the highest rated issues only to a
small degree.  A - Bonds rated A have a strong capacity to pay interest and
repay principal although they are somewhat more susceptible to the adverse
effects of changes in circumstances and economic conditions than bonds in higher
rated categories.  BBB - Debt rated BBB is regarded as having an adequate
capacity to pay interest and repay principal.  Whereas it normally exhibits
adequate protection parameters, adverse economic conditions or changing
circumstances are more likely to lead to a weakened capacity to pay interest and
repay principal for debt in this category than for debt in higher rated
categories.  BB, B, CCC, CC - Debt rated BB, B, CCC and CC is regarded, on
balance, as predominantly speculative with respect to capacity to pay interest
and repay principal in accordance with the terms of the obligation.  BB
indicates the lowest degree of speculation and CC the highest degree of
speculation.  While such debt will likely have some quality and protective
characteristics, these are outweighed by large uncertainties or major risk
exposures to adverse conditions.  C - The rating C is reserved for income bonds
on which no interest is being paid.  D - Debt rated D is in default, and payment
of interest and/or repayment of principal is in arrears.



                                       61
<PAGE> 


     DESCRIPTION OF MOODY'S RATINGS OF STATE AND MUNICIPAL NOTES:  Moody's
ratings for state and municipal notes and other short-term obligations are
designated Moody's Investment Grade ("MIG").  Symbols used are as follows:
MIG-1 -- best quality, enjoying strong protection from established cash flows of
funds for their servicing or from established broad-based access to the market
for refinancing, or both; MIG-2 -- high quality with margins of protection ample
although not so large as in the preceding group; MIG-3 - favorable quality, with
all security elements accounted for but lacking the undeniable strength of the
preceding grades.

     DESCRIPTION OF MOODY'S HIGHEST COMMERCIAL PAPER RATING:  Prime-1 ("P1")
- -- Judged to be of the best quality.  Their short-term debt obligations carry
the smallest degree of investment risk.

     EXCERPT FROM S&P'S RATING OF MUNICIPAL NOTE ISSUES:  S-1+ -- very strong
capacity to pay principal and interest; SP-2 -- strong capacity to pay principal
and interest.

     DESCRIPTION OF S&P'S HIGHEST COMMERCIAL PAPER RATINGS:  A-1+ -- this
designation indicates the degree of safety regarding timely payment is
overwhelming.  A-1 -- this designation indicates the degree of safety regarding
timely payment is very strong.



                                       62
<PAGE> 


                              FINANCIAL STATEMENTS 
   
The Fund's financial statements for the fiscal year ended December 31, 1996, 
including notes thereto and the report of Price Waterhouse LLP are herein 
incorporated by reference from the Fund's Annual report. A copy of the Fund's 
Annual Report to Shareholders must accompany the delivery of this Statement of 
Additional Information.

    


                                       63

<PAGE>


                     MORGAN STANLEY INSTITUTIONAL FUND, INC.
                       STATEMENT OF ADDITIONAL INFORMATION

     Morgan Stanley Institutional Fund, Inc. (the "Fund") is a no-load, open-end
management investment company with diversified and nondiversified series
("Portfolios").  The Fund currently consists of twenty-nine Portfolios offering
a broad range of investment choices.  The Fund is designed to provide clients
with attractive alternatives for meeting their investment needs.  Shares of each
Portfolio are offered with no sales charge, exchange or (with the exception of
the International Small Cap Portfolio) redemption fee.  The Class A shares and
Class B shares currently offered by the Portfolios have different minimum
investment requirements and fund expenses.  This Statement of Additional
Information addresses information of the Fund applicable to Class A shares and
Class B shares of the Technology Portfolio (the "Portfolio"), one of the twenty-
nine portfolios.

     This Statement of Additional Information is not a prospectus but should be
read in conjunction with the prospectus of the Portfolio (the "Prospectus").  To
obtain the Prospectus or the prospectus and/or Statement of Additional
Information relating to any of the other Portfolios, please call the Morgan
Stanley Institutional Fund, Inc. Services Group at 1-800-548-7786.

                                TABLE OF CONTENTS

                                                                           Page




Investment Objective and Policies. . . . . . . . . . . . . . . . . . . . . . 2
Taxes. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
General Regulated Investment Company Qualification . . . . . . . . . . . . . 8
General Tax Treatment of Qualifying RICs and Shareholders. . . . . . . . . . 9
Special Tax Considerations Relating to Foreign Investments . . . . . . . . .10
Taxes and Foreign Shareholders . . . . . . . . . . . . . . . . . . . . . . .10
Purchase of Shares . . . . . . . . . . . . . . . . . . . . . . . . . . . . .11
Redemption of Shares . . . . . . . . . . . . . . . . . . . . . . . . . . . .11
Shareholder Services . . . . . . . . . . . . . . . . . . . . . . . . . . . .12
Investment Limitations . . . . . . . . . . . . . . . . . . . . . . . . . . .12
Determining Maturities of Certain Instruments. . . . . . . . . . . . . . . .14
Management of the Fund . . . . . . . . . . . . . . . . . . . . . . . . . . .14
Performance Information. . . . . . . . . . . . . . . . . . . . . . . . . . .26
General Information. . . . . . . . . . . . . . . . . . . . . . . . . . . . .29
Description of Ratings . . . . . . . . . . . . . . . . . . . . . . . . . . .30
Financial Statements . . . . . . . . . . . . . . . . . . . . . . . . . . . .35

STATEMENT OF ADDITIONAL INFORMATION DATED MAY 1, 1997.

<PAGE>


                        INVESTMENT OBJECTIVE AND POLICIES

     The following policies supplement the Portfolio's investment objective and
policies set forth in the Prospectus:

THE EQUITY-LINKED SECURITIES

    The Portfolio may invest in equity-linked securities, including, among
others, PERCS, ELKS or LYONs, which are securities that are convertible into
or the value of which is based upon the value of, equity securities upon
certain terms and conditions. The amount received by an investor at maturity
of such securities is not fixed but is based on the price of the underlying
common stock. It is impossible to predict whether the price of the underlying
common stock will rise or fall. Trading prices of the underlying common stock
will be influenced by the issuer's operational results, by complex,
interrelated political, economic, financial, or other factors affecting the
capital  markets, the  stock exchanges  on which  the underlying common stock
is traded and the market segment of which the issuer is a part. In addition,
it is not possible to predict how equity-linked securities will trade in the
secondary market, which is fairly developed and liquid. The market for such
securities may be shallow, however, and high volume trades may be possible 
only with discounting. In addition to the foregoing risks, the return on such 
securities depends on the creditworthiness of the issuer of the securities, 
which may be the issuer of the underlying securities or a third party 
investment banker or other lender. The creditworthiness of such third party 
issuer of equity-linked securities may, and often does, exceed the 
creditworthiness of the issuer of the underlying securities. The advantage of 
using equity-linked securities over traditional equity and debt securities is 
that the former are income producing vehicles that may provide a higher 
income than the dividend income on the underlying equity securities while 
allowing some participation in the capital appreciation of the underlying 
equity securities. Another advantage of using equity-linked securities is 
that they may be used for hedging to reduce the risk of investing in the 
generally more volatile underlying equity securities.
 
    The following are three examples of equity-linked securities. The 
Portfolio may invest in the securities described below or other similar 
equity-linked securities.
 
    PERCS.   Preferred Equity Redemption Cumulative Stock ("PERCS") 
technically is preferred stock with some characteristics of common stock. 
PERCS are mandatorily convertible into common stock after a period of time, 
usually three years, during which the investors' capital gains are capped, 
usually at 30%. Commonly, PERCS may be redeemed by the issuer at any time or 
if the issuer's common stock is trading at a specified price level or better. 
The redemption price starts at the beginning of the PERCS duration period at 
a price that is above the cap by the amount of the extra dividends the PERCS 
holder is entitled to receive relative to the common stock over the duration 
of the PERCS and declines to the cap price shortly before maturity of the 
PERCS. In exchange for having the cap on capital gains and giving the issuer 
the option to redeem the PERCS at any time or at the specified common stock 
price level, the Portfolio may be compensated with a substantially higher 
dividend yield than that on the underlying common stock. Investors, such as 
the Portfolio, that seek current income find PERCS attractive because PERCS 
provide a higher dividend income than that paid with respect to a company's 
common stock.
 
    ELKS.    Equity-Linked Securities ("ELKS")  differ from ordinary debt 
securities, in that the principal amount received at maturity is not fixed 
but is based on the price of the issuer's common stock. ELKS are debt 
securities commonly issued in fully registered form for a term of three years 
under an indenture trust. At maturity, the holder of ELKS will be entitled to 
receive a principal amount equal to the lesser of a cap amount, commonly in 
the range of 30% to 55% greater than the current price of the issuer's common 
stock, or the average closing price per share of the issuer's common stock, 
subject to adjustment as a result of certain dilution events, for the 10 
trading days immediately prior to maturity. Unlike PERCS, ELKS are commonly 
not subject to redemption prior to maturity. ELKS usually bear interest 
during the three-year term at a substantially higher rate than the dividend 
yield on the underlying common stock. In exchange for having the cap on the 
return that might have been received as capital gains on the underlying 
common stock, the Portfolio may be compensated with the higher yield, 
contingent on how well the underlying common stock does. Investors, such as 
the Portfolio, that seek current income, find ELKS attractive because ELKS 
provide a higher dividend income than that paid with respect to a company's 
common stock.
 
    LYONS.   Liquid Yield Option Notes ("LYONs") differ from ordinary debt 
securities, in that the amount received prior to maturity is not fixed but is 
based on the  price of  the issuer's  common stock.  LYONs are  zero-coupon 
notes that sell at a large discount from face value. For an investment in 
LYONs, the Portfolio will not receive any interest payments until the notes 
mature, typically in 15 to 20 years, when the notes are redeemed at face, or 
par, value. The yield on LYONs, typically, is lower-than-market rate for debt 
securities of the same maturity, due in part to the fact that the LYONs are 
convertible into common stock of the issuer at any time at the option of the 
holder of the LYONs. Commonly, the LYONs are redeemable by the issuer at any 
time after an initial period or if the issuer's common stock is trading at a 
specified price level or better or, at the option of the holder, upon certain 
fixed dates. The redemption price typically is the purchase price of the 
LYONs plus accrued original issue discount to the date of redemption, which 
amounts to the  lower-than-market  yield.  The  Portfolio  will  receive  
only  the lower-than-market yield unless the underlying common stock 
increases in value at a substantial rate. LYONs are attractive to investors 
like the Portfolio when it appears that they will increase in value due to 
the rise in value of the underlying common stock.

FOREIGN CURRENCY TRANSACTIONS

     To the extent the Portfolio invests in securities denominated in foreign 
currencies, the assets of the Portfolio may be affected favorably or 
unfavorably by changes in foreign currency exchange rates and exchange 
control regulations, and the Portfolio may incur costs in connection with 
conversions between various currencies.  The Portfolio will conduct its 
foreign currency exchange transactions either on a spot (i.e., cash) basis at 
the spot rate prevailing in the foreign currency exchange market, or through 
entering into forward contracts to purchase or sell foreign currencies.  A 
foreign currency forward contract involves an obligation to purchase or sell 
a specific currency at a future date, which may be any fixed number of days 
from the date of the contract agreed upon by the parties, at a price set at 
the time of the contract.  These contracts are traded in the interbank market 
conducted directly between currency traders (usually large commercial banks) 
and their customers.  A forward contract generally has no deposit 
requirement, and no commissions are charged at any stage for such trades.

     The Portfolio may enter into foreign currency forward contracts in 
several circumstances.  When the Portfolio enters into a contract for the 
purchase or sale of a security denominated in a foreign currency, or when the 
Portfolio anticipates the receipt in a foreign currency of dividends or 
interest payments on a security which it holds, the Portfolio may desire to 
"lock-in" the U.S. dollar price of the security or the U.S. dollar equivalent 
of such dividend or interest payment, as the case may be.  By entering into a 
forward contract for a fixed amount of dollars, for the purchase or sale of 
the amount of foreign currency involved in the underlying transactions, the 
Portfolio will be able to protect itself against a possible loss resulting 
from an adverse change in the relationship between the U.S. dollar and the 
subject foreign currency during the period between the date on which the 
security is purchased or sold, or on which the dividend or interest payment 
is declared, and the date on which such payments are made or received.

     Additionally, when the Portfolio anticipates that the currency of a 
particular foreign country may suffer a substantial decline against the U.S. 
dollar, it may enter into a forward contract for a fixed amount of dollars, 
to sell the amount of foreign currency approximating the value of some or all 
of the Portfolio's securities denominated in such foreign currency.  The 
precise matching of the forward contract amounts and the value of the 
securities involved will not generally be possible since the future value of 
securities in foreign currencies will change as a consequence of market 
movements in the value of these securities between the date on which the 
forward contract is entered into and the date it matures.  The projection of 
short-term currency market movement is extremely difficult, and the 
successful execution of a short-term hedging strategy is highly uncertain. 
The Portfolio does not intend to enter into such forward contracts to protect 
the value of portfolio securities on a continuous basis.  The Portfolio will 
not enter into such forward contracts or maintain a net exposure to such 
contracts where the consummation of the contracts would obligate the 
Portfolio to deliver an amount of foreign currency in excess of the value of 
its securities or other assets denominated in that currency.

     Under normal circumstances, consideration of the prospect for currency
parities will be incorporated into the long-term investment decisions made with
regard to overall diversification strategies.  However, the management of the
Fund believes that it is important to have the flexibility to enter into such
forward contracts when it determines that the best interests of the performance
of the Portfolio will thereby be served.  Except under circumstances where a
segregated account is not required under the 1940 Act or the rules adopted
thereunder, the Fund's Custodian will place cash, U.S. or liquid securities 
into a segregated account of the Portfolio in an amount equal to the value
of its total assets committed to the consummation of forward currency
exchange contracts.  If the value of the securities placed in the 
segregated account declines, additional cash or securities will be placed in
the account on a daily basis so that the value of the account will be equal to
the amount of the Portfolio's commitments with respect to such contracts.

     The Portfolio generally will not enter into a forward contract with a term
of greater than one year.  At the maturity of a forward contract, the Portfolio
may either sell the portfolio security and make delivery of the foreign
currency, or it may retain the security and terminate its contractual obligation
to deliver the foreign currency by purchasing an "offsetting" contract with the
same currency trader obligating it to purchase, on the same maturity date, the
same amount of the foreign currency.

     It is impossible to forecast with absolute precision the market value of a
particular portfolio security at the expiration of the contract.  Accordingly,
it may be necessary for the Portfolio to purchase additional foreign currency on
the spot market (and bear the expense of such purchase) if the market value of
the security is less than the amount of foreign currency that the Portfolio is
obligated to deliver and if a decision is made to sell the security and make
delivery of the foreign currency.




                                        2
<PAGE>


     If the Portfolio retains the portfolio security and engages in an
offsetting transaction, the Portfolio will incur a gain or a loss (as described
below) to the extent that there has been movement in forward contract prices.
Should forward prices decline during the period between the Portfolio entering
into a forward contract for the sale of a foreign currency and the date it
enters into an offsetting contract for the purchase of the foreign currency, the
Portfolio will realize a gain to the extent that the price of the currency it
has agreed to sell exceeds the price of the currency it has agreed to purchase.
Should forward prices increase, the Portfolio would suffer a loss to the extent
that the price of the currency it has agreed to purchase exceeds the price of
the currency it has agreed to sell.

     The Portfolio is not required to enter into such transactions with regard
to its foreign currency-denominated securities.  It also should be realized that
this method of protecting the value of portfolio securities against a decline in
the value of a currency does not eliminate fluctuations in the underlying prices
of the securities.  It simply establishes a rate of exchange which one can
achieve at some future point in time.  Additionally, although such contracts
tend to minimize the risk of loss due to a decline in the value of the hedged
currency, at the same time, they tend to limit any potential gain which might
result should the value of such currency increase. For a discussion of the
special risks associated with foreign currency transactions, see "Risks
Associated with Foreign Currency Transactions," below in this SAI.

RISKS ASSOCIATED WITH FOREIGN CURRENCY TRANSACTIONS

     Transactions in foreign currency forward contracts, foreign currency 
futures contracts and options thereon, and options on foreign currencies, are 
subject to the risk of governmental actions affecting trading in or the 
prices of currencies underlying such contracts, which could restrict or 
eliminate trading and could have a substantial adverse effect on the value of 
positions held by the Portfolio permitted to engage in such hedging 
transactions.  In addition, the value of such positions could be adversely 
affected by a number of other complex political and economic factors 
applicable to the countries issuing the underlying currencies.

     Furthermore, unlike trading in most other types of instruments, there is no
systematic reporting of last sale information with respect to the foreign
currencies underlying forward contracts, futures contracts and options.  As a
result, the available information on which the Portfolio's trading systems will
be based may not be as complete as the comparable data on which the Portfolio
makes investment and trading decisions in connection with securities and other
transactions.  Moreover, because the foreign currency market is a global,
twenty-four hour market, events could occur on that market which will not be
reflected in the forward, futures or options markets until the following day,
thereby preventing the Portfolio from responding to such events in a timely
manner.

     Settlement of OTC forward contracts or the exercise of foreign currency 
options generally must occur within the country issuing the underlying 
currency, which in turn requires parties to such contracts to accept or make 
delivery of such currencies in conformity with any United States or foreign 
restrictions and regulations regarding the maintenance of foreign banking 
relationships, fees, taxes or other charges.

     Unlike currency futures contracts and exchange-traded options, OTC 
options on foreign currencies and foreign currency forward contracts are not 
traded on contract markets or national securities exchanges regulated by the 
CFTC or the Commission, respectively.  In an OTC trading environment, many of 
the protections associated with transactions on exchanges will not be 
available. For example, there are no daily price fluctuation limits, and 
adverse market movements could therefore continue to an unlimited extent over 
a period of time. Although the purchaser of an option cannot lose more than 
the amount of the premium plus related transaction costs, this entire amount 
could be lost.  Moreover, an option writer could lose amounts substantially 
in excess of its initial investment due to the margin and collateral 
requirements associated with such option positions.  Similarly, there is no 
limit on the amount of potential losses on forward contracts to which the 
Portfolio is a party.

     In addition, OTC transactions can only be entered into with a financial 
institution willing to take the opposite side, as principal, of the 
Portfolio's position unless the institution acts as broker and is able to 
find another counterparty willing to enter into the transaction with the 
Portfolio. Where no such counterparty is available, it will not be possible 
to enter into a desired transaction.  There also may be no liquid secondary 
market in the trading of OTC contracts, and the Portfolio may be unable to 
close out options purchased or written, or forward contracts entered into, 
until their exercise, expiration or maturity.  This in turn could limit the 
Portfolio's ability to realize profits or to reduce losses on open positions 
and could result in greater losses.

     Furthermore, OTC transactions are not backed by the guarantee of an 
exchange's clearing corporation.  The Portfolio will therefore be subject to 
the risk of default by, or the bankruptcy of, the financial institution 
serving as its counterparty.  One or more of such institutions also may 
decide to discontinue its role as market-maker in a particular currency, 
thereby restricting the Portfolio's ability to enter into desired hedging 
transactions. The Portfolio will enter into OTC transactions only with 
parties whose creditworthiness has been reviewed and found satisfactory by 
the Adviser.

     OTC options on foreign currencies are within the exclusive regulatory 
jurisdiction of the CFTC.  The CFTC currently permits the trading of such 
options, but only subject to a number of conditions regarding the commercial 
purpose of the purchaser of such options.

     Options on foreign currencies traded on a national securities exchange 
are within the jurisdiction of the Commission, as are other securities traded 
on such exchanges.  As a result, many of the protections provided to traders 
on organized exchanges will be available with respect to such transactions.  
In particular, all foreign currency options positions entered into on a 
national securities exchange are cleared and guaranteed by the Options 
Clearing Corporation ("OCC"), thereby reducing the risk of counterparty 
default. Further, a liquid secondary market in options traded on a national 
securities exchange may be more readily available than in the OTC market, 
potentially permitting the Portfolio to liquidate open positions at a profit 
prior to exercise or expiration, or to limit losses in the event of adverse 
market movements.

     The purchase and sale of exchange-traded foreign currency options, however,
is subject to the risks of the availability of a liquid secondary market
described above, as well as the risks regarding adverse market movements,
margining of options written, the nature of the foreign currency market,
possible intervention by governmental authorities and the effect of other
political and economic events.  In addition, exchange-traded options on foreign
currencies involve certain risks not presented by the over-the-counter market.
For example, exercise and settlement of such options must be made exclusively
through the OCC, which has established banking relationships in applicable
foreign countries for this purpose.  As a result, the OCC may, if it determines
that foreign governmental restrictions or taxes would prevent the orderly
settlement of foreign currency option exercises, or would result in undue
burdens on the OCC or its clearing member, impose special procedures for
exercise and settlement, such as technical changes in the mechanics of delivery
of currency, the fixing of dollar settlement prices or prohibitions on exercise.

FOREIGN INVESTMENTS

     The Portfolio may invest, in securities of foreign issuers.  Investors
should recognize that investing in such foreign securities involves certain
special considerations which are not typically associated with investing in U.S.
issuers. For a description of the effect on the Portfolio of currency exchange
rate fluctuation, see "Investment Objective and Policies -- Forward Foreign
Currency Exchange Contracts" above.  As foreign issuers are not generally
subject to uniform accounting, auditing and financial reporting standards and
may have policies that are not comparable to those of domestic issuers, there
may be less information available about certain foreign companies than about
domestic issuers.  Securities of some foreign issuers are generally less liquid
and more volatile than securities of comparable domestic issuers.  There is
generally less government supervision and regulation of stock exchanges, brokers
and listed issuers than in the U.S.  In addition, with respect to certain
foreign countries, there is the possibility of expropriation or confiscatory
taxation, political or social instability, or diplomatic developments which
could affect U.S. investments in those countries.  Foreign securities not listed
on a recognized domestic or foreign exchange are regarded as not readily
marketable and therefore such investments will be limited to 15% of the
Portfolio's net asset value at the time of purchase.

     Although the Portfolio will endeavor to achieve the most favorable
execution costs in their portfolio transactions, fixed commissions on many
foreign stock exchanges are generally higher than negotiated commissions on U.S.
exchanges.

     Certain foreign governments levy withholding or other taxes on dividend and
interest income.  Although in some countries a portion of these taxes are
recoverable, the non-recovered portion of foreign withholding taxes will reduce
the income received from investments in such countries.  It is not expected that
the Portfolio or its shareholders would be able to claim a credit for U.S. tax
purposes with respect to any such foreign taxes.  However, these foreign
withholding taxes may not have a significant impact on the Portfolio, because
the Portfolio's investment objective is to seek long-term capital appreciation
and any dividend or interest income should be considered incidental.

FUTURES CONTRACTS

     The Portfolio may enter into futures contracts and options on futures
contracts for the purpose of remaining fully invested and reducing transactions
costs and may also enter into futures contracts for hedging purposes.  The
Portfolio will not enter into futures contracts or options thereon for
speculative purposes.  Futures contracts provide for the future sale by one
party and purchase by another party of a specified amount of a specific security
at a specified future time and at a specified price.  Futures contracts, which
are standardized as to maturity date and underlying financial instrument, are
traded on national futures exchanges.  Futures exchanges and trading are
regulated under the Commodity Exchange Act by the Commodity Futures Trading
Commission ("CFTC"), a U.S. government agency.

     Although futures contracts by their terms call for actual delivery or
acceptance of the underlying securities or currencies, in most cases the
contracts are closed out before the settlement date without the making or taking
of delivery.  Closing out an open futures position is done by taking an opposite
position ("buying" a contract which has previously been "sold" or "selling" a
contract previously "purchased") in an identical contract to terminate the
position.  Brokerage commissions are incurred when a futures contract is bought
or sold.

     Futures contracts on securities indices or other indices do not require the
physical delivery of securities, but merely provide for profits and losses
resulting from changes in the market value of a contract to be credited or
debited at the close of each trading day to the respective accounts of the
parties to the contract.  On the contract's expiration date a final cash
settlement occurs and the futures position is simply closed out.  Changes in the
market value of a particular futures contract reflect changes in the level of
the index on which the futures contract is based.

     Futures traders are required to make a good faith margin deposit in cash or
government securities with a broker or custodian to initiate and maintain open
positions in futures contracts.  A margin deposit is intended to assure
completion of the contract (delivery or acceptance of the underlying security)
if it is not terminated prior to the specified delivery date.  Minimal initial
margin requirements are established by the futures exchange and may be changed.
Brokers may establish deposit requirements which are higher than the exchange
minimums.  Futures contracts are customarily purchased and sold for prices that
may range upward from less than 5% of the value of the contract being traded.

     After a futures contract position is opened, the value of the contract is
marked to market daily.  If the futures contract price changes to the extent
that the margin on deposit does not satisfy margin requirements, payment of an
additional "variation" margin will be required.  Conversely, a change in the
contract value may reduce the required margin, resulting in a repayment of
excess margin to the contract holder.  Variation margin payments are made to and
from the futures broker for as long as the contract remains open.  The Portfolio
expects to earn interest income on its margin deposits.  With respect to each
long position in a futures contract or option thereon, the underlying commodity
value of such contract will always be covered by cash and cash equivalents set
aside plus accrued profits held at the futures commission merchant.

     The Portfolio may purchase and write call and put options on futures
contracts which are traded on a U.S. Exchange and enter into closing
transactions with respect to such options to terminate an existing position.  An
option on a futures contract gives the purchaser the right (in return for the
premium paid) to assume a position in a futures contract (a long position if the
option is a call and a short position if the option is a put) at a specified
exercise price at any time during the term of the option.  Upon exercise of the
option, the delivery of the accumulated balance in the writer's futures margin
account, which represents the amount by which


                                        3
<PAGE>


the market price of the futures contract at the time of exercise exceeds, in the
case of a call, or is less than, in the case of a put, the exercise price of the
option on the futures contract.

     The Portfolio will purchase and write options on futures contracts for
identical purposes to those set forth above for the purchase of a futures
contract (purchase of a call option or sale of a put option) and the sale of a
futures contract (purchase of a put option or sale of a call option), or to
close out a long or short position in futures contracts.

     Traders in futures contracts may be broadly classified as either "hedgers"
or "speculators."  Hedgers use the futures markets primarily to offset
unfavorable changes in the value of securities otherwise held for investment
purposes or expected to be acquired by them.  Speculators are less inclined to
own the underlying securities with futures contracts which they trade, and use
futures contracts with the expectation of realizing profits from market
fluctuations.  The Portfolio intends to use futures contracts only for hedging
purposes.

     Regulations of the CFTC applicable to the Portfolio require that all
futures transactions constitute bona fide hedging transactions except that the
Portfolio may engage in futures transactions that do not constitute bona fide
hedging to the extent that not more than 5% of the liquidation value of the
Portfolio's total assets are required as margin deposits or premiums for such
transactions.  The Portfolio will only sell futures contracts to protect
securities owned against declines in price or purchase contracts to protect
against an increase in the price of securities intended for purchase.  As
evidence of this hedging interest, the Portfolio expects that approximately 75%
of their futures contracts will be "completed"; that is, equivalent amounts of
related securities will have been purchased or are being purchased by the
Portfolio upon sale of open futures contracts.

     Although techniques other than the sale and purchase of futures contracts
could be used to control the Portfolio's exposure to market fluctuations, the
use of futures contracts may be a more effective means of hedging this exposure.
While the Portfolio will incur commission expenses in both opening and closing
out futures positions, these costs are lower than transaction costs incurred in
the purchase and sale of the underlying securities.

RESTRICTIONS ON THE USE OF FUTURES CONTRACTS.  The Portfolio will not enter into
futures contract transactions to the extent that, immediately thereafter, the
sum of its initial margin deposits on open contracts exceeds 5% of the market
value of its total assets.  In addition, the Portfolio will not enter into
futures contracts to the extent that its outstanding obligations to purchase
securities under futures contracts and options on futures contracts and, under
options, futures contracts and options on futures contracts would exceed 20% of
its total assets.

RISK FACTORS IN FUTURES TRANSACTIONS.  Positions in futures contracts may be
closed out only on an exchange which provides a secondary market for such
futures.  However, there can be no assurance that a liquid secondary market will
exist for any particular futures contracts at any specific time.  Thus, it may
not be possible to close a futures position.  In the event of adverse price
movements, the Portfolio would continue to be required to make daily cash
payments to maintain its required margin.  In such situations, if the Portfolio
has insufficient cash, it may have to sell portfolio securities to meet its
daily margin requirement at a time when it may be disadvantageous to do so.  In
addition, the Portfolio may be required to make delivery of the instruments
underlying futures contracts it holds.  The inability to close options and
futures positions also could have an adverse impact on the Portfolio's ability
to effectively hedge.

     The Portfolio will minimize the risk that it will be unable to close out a
futures contract by only entering into futures which are traded on national
futures exchanges and for which there appears to be a liquid secondary market.

     The risk of loss in trading futures contracts in some strategies can be
substantial, due both to the low margin deposits required, and the extremely
high degree of leverage involved in futures pricing.  As a result, a relatively
small price movement in a futures contract may result in immediate and
substantial loss (as well as gain) to the investor.  For example, if, at the
time of purchase, 10% of the value of the futures contract is deposited as
margin, a subsequent 10% decrease in the value of the futures contract would
result in a total loss of the margin deposit, before any deduction for the
transaction costs, if the account were then closed out.  A 15% decrease would
result in a loss equal to 150% of the original margin deposit if the contract
were closed out.  Thus, a purchase or sale of a futures contract may result in
losses in excess of the amount invested in the contract. However, because the
Portfolio engages in futures strategies only for hedging purposes, the Adviser
does not believe that the Portfolio is subject to the risks of loss frequently
associated with futures transactions.  The Portfolio would presumably have
sustained comparable losses if, instead of the futures contract, it had invested
in the underlying security or currency and sold it after the decline.

     Utilization of futures transactions by the Portfolio does involve the risk
of imperfect or no correlation where the securities underlying futures contracts
have different maturities than the portfolio securities or currencies being
hedged.  It is also possible that


                                        4
<PAGE>


the Portfolio could both lose money on futures contracts and also experience a
decline in value of its portfolio securities.  There is also the risk of loss by
the Portfolio of margin deposits in the event of bankruptcy of a broker with
whom the Portfolio has an open position in a futures contract or related option.


     Most futures exchanges limit the amount of fluctuation permitted in futures
contract prices during a single trading day.  The daily limit establishes the
maximum amount that the price of a futures contract may vary either up or down
from the previous day's settlement price at the end of a trading session.  Once
the daily limit has been reached in a particular type of contract, no trades may
be made on that day at a price beyond that limit.  The daily limit governs only
price movement during a particular trading day and therefore does not limit
potential losses, because the limit may prevent the liquidation of unfavorable
positions.  Futures contract prices have occasionally moved to the daily limit
for several consecutive trading days with little or no trading, thereby
preventing prompt liquidation of futures positions and subjecting some futures
traders to substantial losses. For a discussion of the special risks associated
with foreign currency transactions, see "Risks Associated with Foreign Currency
Transactions" in this SAI.

MORTGAGE-BACKED SECURITIES

      Mortgage-Backed Securities are securities that, directly or indirectly, 
represent a participation in, or are secured by and payable from, mortgage 
loans on real property.  Mortgage-backed securities include collateralized 
mortgage obligations, pass-through securities issued or guaranteed by 
agencies or instrumentalities of the U.S. government or by private sector 
entities.

     COLLATERALIZED MORTGAGE OBLIGATIONS.  Collateralized mortgage obligations
("CMOs") are debt obligations or multiclass pass-through certificates issued by
agencies or instrumentalities of the U.S. government or by private originators
or investors in mortgage loans.  They are backed by Mortgage Pass-Through
Securities (discussed below) or whole loans (all such assets, the "Mortgage
Assets") and are evidenced by a series of bonds or certificates issued in
multiple classes or "tranches."  The principal and interest on the underlying
Mortgage Assets may be allocated among the several classes of a series of CMOs
in many ways.

     CMOs may be issued by agencies or instrumentalities of the U.S. government,
or by private originators of, or investors in, mortgage loans, including savings
and loan associations, mortgage bankers, commercial banks, investment banks and
special purpose subsidiaries of the foregoing.  CMOs that are issued by private
sector entities and are backed by assets lacking a guarantee of an entity having
the credit status of a governmental agency or instrumentality are generally
structured with one or more types of credit enhancement as described below.  An
issuer of CMOs may elect to be treated, for federal income tax purposes, as a
Real Estate Mortgage Investment Conduit (a "REMIC").  An issuer of CMOs issued
after 1991 must elect to be treated as a REMIC or it will be taxable as a
corporation under rules regarding taxable mortgage pools.

     In a CMO, a series of bonds or certificates are issued in multiple 
classes. Each tranche may be issued with a specific fixed or floating coupon 
rate and has a stated maturity or final scheduled distribution date.  
Principal prepayments on the underlying Mortgage Assets may cause the CMOs to 
be retired substantially earlier than their stated maturities or final 
scheduled distribution dates.  Interest is paid or accrues on CMOs on a 
monthly, quarterly or semi-annual basis.  The principal of and interest on 
the Mortgage Assets may be allocated among the several classes of a CMO in 
many ways.  The general goal in allocating cash flows on Mortgage Assets to 
the various classes of a CMO is to create certain tranches on which the 
expected cash flows have a higher degree of predictability than the 
underlying Mortgage Assets.  As a general matter, the more predictable the 
cash flow is on a particular CMO tranche, the lower the anticipated yield 
will be on that tranche at the time of issuance relative to prevailing market 
yields on Assets. As part of the process of creating more predictable cash 
flows on certain tranches of a CMO, one or more tranches generally must be 
created that absorb most of the changes in the cash flows on the underlying 
Mortgage Assets.  The yields on these tranches are generally higher than 
prevailing market yields on Mortgage-Backed Securities with similar average 
lives.  Because of the uncertainty of the cash flows on these tranches, the 
market prices of and yields on these tranches are more volatile.

     Included within the category of CMOs are PAC Bonds.  PAC Bonds are a type
of CMO tranche or series designed to provide relatively predictable payments of
principal provided that, among other things, the actual prepayment experience on
the underlying mortgage loans falls within a predefined range.  If the actual
prepayment experience on the underlying mortgage loans is at a rate faster or
slower than the predefined range or if deviations from other assumptions occur,
principal payments on the PAC Bond may be earlier or later than predicted.  The
magnitude of the predefined range varies from one PAC Bond to another; a
narrower range increases the risk that prepayments on the PAC Bond will be
greater or smaller than predicted.  Because of these features, PAC Bonds
generally are less subject to the risks of prepayment than are other types of
mortgage-backed securities.

      MORTGAGE PASS-THROUGH SECURITIES.  Mortgage pass-through securities in 
which the Mortgage-Backed Securities Portfolio may invest include 
pass-through securities issued or guaranteed by agencies or instrumentalities 
of the U.S. government or by private sector entities.  Mortgage pass-through 
securities issued or guaranteed by private sector originators of or investors 
in mortgage loans and are structured similarly to governmental pass-through 
securities. Because private pass-throughs typically lack a guarantee by an 
entity having the credit status of a governmental agency or instrumentality, 
they are generally structured with one or more types of credit enhancement 
described below.  Federal National Mortgage Association ("FNMA" or "Fannie 
Mae") and Federal Home Loan Mortgage Corporation ("FHLMC" or "Freddie Mac") 
obligations are not backed by the full faith and credit of the U.S. 
government as Government National Mortgage Association ("GNMA" or "Ginnie 
Mae") certificates are, but FNMA and FHLMC securities are supported by the 
instrumentalities' right to borrow from the U.S. Treasury.  Each of GNMA, 
GNMA and FHLMC guarantees timely distributions of interest to certificate 
holders.

      Each of GNMA and FNMA also guarantees timely distributions of scheduled
principal.  FHLMC has in the past guaranteed only the ultimate collection of
principal of the underlying mortgage loan; however, FHLMC now issues Mortgage-
Backed Securities (FHLMC Gold Pcs) which also guarantee timely payment of
monthly principal reductions.  REFCORP obligations are backed, as to principal
payments, by zero coupon U.S. Treasury bonds, and as to interest payment,
ultimately by the U.S. Treasury.  Obligations issued by such U.S. governmental
agencies and instrumentalities are described more fully below.


     GINNIE MAE CERTIFICATES.  Ginnie Mae is a wholly-owned corporate
instrumentality of the United States within the Department of Housing and Urban
Development.  The National Housing Act of 1934, as amended (the "Housing Act"),
authorizes Ginnie Mae to guarantee the timely payment of the principal of and
interest on certificates that are based on and backed by a pool of mortgage
loans insured by the Federal Housing Administration under the Housing Act, or
Title V of the Housing Act of 1949 ("FHA Loans"), or guaranteed by the
Department of Veterans Affairs under the Servicemen's Readjustment Act of 1944,
as amended ("VA Loans"), or by pools of other eligible mortgage loans.  The
Housing Act provides that the full faith and credit of the United States
government is pledged to the payment of all amounts that may be required to be
paid under any guaranty.  In order to meet its obligations under such guaranty,
Ginnie Mae is authorized to borrow from the U.S. Treasury with no
limitations as to amount.

     Each Ginnie Mae Certificate will represent a pro rata interest in one or
more of the following types of mortgage loans: (i) fixed rate level payment
mortgage loans; (ii) fixed rate graduated payment mortgage loans; (iii) fixed
rate growing equity mortgage loans; (iv) fixed rate mortgage loans secured by
manufactured (mobile) homes; (v) mortgage loans on multi-family residential
properties under construction; (vi) mortgage loans on completed multi-family
projects; (vii) fixed rate mortgage loans as to which escrowed funds are used to
reduce the borrower's monthly payments during the early years of the mortgage
loans ("buydown" mortgage loans); (viii) mortgage loans that provide for
adjustments in payments based on periodical changes in interest rates or in
other payment terms of the mortgage loans; and (ix) mortgage-backed serial
notes.  All of these mortgage loans will be FHA Loans or VA Loans and, except as
otherwise specified above, will be fully-amortizing loans secured by first liens
on one- to four-family housing units.

     FANNIE MAE CERTIFICATES.  Fannie Mae is a federally chartered and privately
owned corporation organized and existing under the Federal National Mortgage
Association Charter Act of 1938.  The obligations of Fannie Mae are not backed
by the full faith and credit of the U.S. government.

     Each Fannie Mae Certificate will represent a pro rata interest in one or
more pools of FHA Loans, VA Loans or conventional mortgage loans (i.e., mortgage
loans that are not insured or guaranteed by any governmental agency) of the
following types: (i) fixed rate level payment mortgage loans; (ii) fixed rate
growing equity mortgage loans; (iii) fixed rate graduated payment mortgage
loans; (iv) variable rate California mortgage loans; (v) other adjustable rate
mortgage loans; and (vi) fixed rate and adjustable mortgage loans secured by
multi-family projects.

     FREDDIE MAC CERTIFICATES.  Freddie Mac is a corporate instrumentality of
the United States created pursuant to the Emergency Home Finance Act of 1970, as
amended (the "FHLMC Act").  The obligations of Freddie Mac are obligations
solely of Freddie Mac and are not backed by the full faith and credit of the
U.S. government.

     Freddie Mac Certificates represent a pro rata interest in a group of
mortgage loans (a "Freddie Mac Certificate group") purchased by Freddie Mac.
The mortgage loans underlying the Freddie Mac Certificates will consist of fixed
rate or adjustable rate mortgage loans with original terms to maturity of
between ten and thirty years, substantially all of which are secured by first
liens on one- to four-family residential properties or multi-family projects.
Each mortgage loan must meet the applicable standards set forth in the FHLMC
Act.  A Freddie Mac Certificate group may include whole loans, participation
interests in whole loans and undivided interests in whole loans and
participations comprising another Freddie Mac Certificate group.

     CREDIT ENHANCEMENT.  Mortgage-backed securities are often backed by a pool
of assets representing the obligations of a number of different parties.  To
lessen the effect of failure by obligors on underlying assets to make payments,
such securities may contain elements of credit support.  Such credit support
falls into two categories: (i) liquidity protection and (ii) protection against
losses resulting from ultimate default by an obligor on the underlying assets.
Liquidity protection generally refers to the provision of advances, typically by
the entity administering the pool of assets, to ensure that the pass-through of
payments due on the underlying pool occurs in a timely fashion.  Protection
against losses resulting from ultimate default enhances the likelihood of
ultimate payment of the obligations on at least a portion of the assets in the
pool.  Such protection may be provided through guarantees, insurance policies or
letters of credit obtained by the issuer or sponsor from third parties (referred
to herein as "third party credit support), through various means of structuring
the transaction or through a combination of such approaches.  The Mortgage-
Backed Securities Portfolio will not pay any additional fees for such credit
support, although the existence of credit support may increase the price the
Portfolio pays for a security.

     The ratings of mortgage-backed securities for which third-party credit
enhancement provides liquidity protection or protection against losses from
default are generally dependent upon the continued creditworthiness of the
provider of the credit enhancement.  The ratings of such securities could be
subject to reduction in the event of deterioration in the creditworthiness of
the credit enhancement provider even in cases where the delinquency and loss
experience on the underlying pool of assets is better than expected.

     Examples of credit support arising out of the structure of the transaction
include "senior-subordinated securities" (multiple class securities with one or
more classes subordinate to other classes as to the payment of principal thereof
and interest thereon, with defaults on the underlying assets being borne first
by the holders of the most subordinated class), creation of "reserve funds"
(where cash or investments, sometimes funded from a portion of the payments on
the underlying assets, are held in reserve against future losses) and
"over-collateralization" (where the scheduled payments on, or the principal
amount of, the underlying assets exceed those required to make payment of the
securities and pay any servicing or other fees).  The degree of credit support
provided for each security is generally based on historical information with
respect to the level of credit risk associated with the underlying assets.
Delinquency or loss in excess of that which is anticipated could adversely
affect the return on an investment in such a security.

MUNICIPAL BONDS

     Municipal Bonds generally include debt obligations issued by states and
their political subdivisions, and duly constituted authorities and corporations,
to obtain funds to construct, repair or improve various public facilities such
as airports, bridges, highways, hospitals, housing, schools, streets and water
and sewer works.  Municipal Bonds may also be issued to refinance outstanding
obligations as well as to obtain funds for general operating expenses and for
loans to other public institutions and facilities.

     The two principal classifications of Municipal Bonds are "general
obligation" and "revenue" or "special tax" bonds.  General obligation bonds are
secured by the issuer's pledge of its full faith, credit and taxing power for
the payment of principal and interest.  Revenue or special tax bonds are payable
only from the revenues derived from a particular facility or class of facilities
or, in some cases, from the proceeds of a special excise or other tax, but not
from general tax revenues.  The Municipal Bond Portfolio and the Municipal Money
Market Portfolio may also invest in tax-exempt industrial development bonds,
short-term municipal obligations, project notes, demand notes and tax-exempt
commercial paper in accordance with the Portfolio's investment objectives and
policies.

     Industrial revenue bonds (i.e., private activity bonds) in most cases are
revenue bonds and generally do not have the pledge of the credit of the issuer.
The payment of the principal and interest on such industrial revenue bonds is
dependent solely on the ability of the user of the facilities financed by the
bonds to meet its financial obligations and the pledge, if any, of real and
personal property so financed as security for such payment.  Short-term
municipal obligations issued by states, cities, municipalities or municipal
agencies include Tax Anticipation Notes, Revenue Anticipation Notes, Bond
Anticipation Notes, Construction Loan Notes and Short-Term Discount Notes.
Project Notes are instruments guaranteed by the Department of Housing and Urban
Development but issued by a state or local housing agency.  While the issuing
agency has the primary obligation on such Project notes, they are also secured
by the full faith and credit of the United States.

     Note obligations with demand or put options may have a stated maturity 
in excess of one year, but allow any holder to demand payment of principal 
plus accrued interest upon a specified number of days notice.  Frequently, 
such obligations are secured by letters of credit or other credit support 
arrangements provided by banks.  The issuer of such notes normally has a 
corresponding right, after a given period, to repay in its discretion the 
outstanding principal of the notes plus accrued interest upon a specific 
number of days notice to the bondholders.  The interest rate on a demand note 
may be based upon a known lending rate, such as a bank's prime rate, and may 
be adjusted when such rate changes, or the interest rate on a demand note may 
be a market rate that is adjusted at specified intervals.  The demand notes 
in which the Municipal Money Market Portfolio will invest are payable on not 
more than one year's notice.

     The yields of Municipal Bonds depend on, among other things, general money
market conditions, conditions in the Municipal Bond market, the size of a
particular offering, the maturity of the obligation, and the rating of the
issue.  The ratings of Moody's and S&P represent their opinions of the quality
of the Municipal Bonds.  It should be emphasized that such ratings are general
and are not absolute standards of quality.  Consequently, Municipal Bonds with
the same maturity, coupon and rating may have different yields, while Municipal
Bonds of the same maturity and coupon, but with different ratings, may have the
same yield.  It will be the responsibility of the Adviser to appraise
independently the fundamental quality of the bonds held by the Municipal Bond
Portfolio and the Municipal Money Market Portfolio.

     Municipal Bonds are sometimes purchased on a "when issued" basis meaning
the buyer has committed to purchasing certain specified securities at an
agreed-upon price when they are issued.  The period between commitment date and
issuance date can be a month or more.  It is possible that the securities will
never be issued and the commitment canceled.

     From time to time proposals have been introduced before Congress to
restrict or eliminate the Federal income tax exemption for interest on Municipal
Bonds.  Similar proposals may be introduced in the future.  If any such proposal
were enacted, it might restrict or eliminate the ability of either the Municipal
Bond Portfolio or the Municipal Money Market Portfolio to achieve its investment
objective.  In that event, the Fund's Directors and officers would reevaluate
its investment objective and policies and consider recommending to its
shareholders changes in such objective and policies.

     Similarly, from time to time proposals have been introduced before State
and local legislatures to restrict or eliminate the State and local income tax
exemption (to the extent such an exemption applies, which may not apply in all
cases) for interest on Municipal Bonds.  Similar proposals may be introduced in
the future.  If any such proposal were enacted, it might restrict or eliminate
the ability of either of the Municipal Bond Portfolio or the Municipal Money
Market Portfolio to achieve its investment objective.  In that event, the Fund's
Directors and officers would reevaluate the Portfolio's investment objective and
policies and consider recommending to its shareholders changes in such objective
and policies.

OPTIONS TRANSACTIONS


GENERAL INFORMATION.  As stated in the Prospectus, the Portfolio may purchase
and sell options on equity securities.  Additional information with respect to
option transactions is set forth below.  Call and put options on portfolio
securities are listed on various U.S. and foreign securities exchanges ("listed
options") and are written in over-the-counter transactions ("OTC Options").

     Listed options are issued or guaranteed by the exchange on which they 
trade or by a clearing corporation, such as Options Clearing Corporation 
("OCC") in the United States.  Ownership of a listed call option gives the 
fund the right to buy from the clearing corporation or exchange, the 
underlying security covered by the option at the state exercise price (the 
price per unit of the underlying security or currency) by filing an exercise 
notice prior to the expiration date of the option.  The writer (seller) of 
the option would then have the obligation to sell to the clearing corporation 
or exchange, the underlying security or currency at that exercise price prior 
to the expiration date of the option, regardless of the current market price. 
 Ownership of a listed put option would give the Portfolio the right to sell 
the underlying security or currency to the clearing corporation or exchange 
at the state exercise price. Upon notice of exercise of the put option, the 
writer of the option would have the obligation to purchase the underlying 
security from the clearing corporation or exchange at the exercise price.

     OTC options are purchased from or sold (written) to dealers of financial
institutions which have entered into direct agreements with the Portfolio.  With
OTC options, such variables as expiration date, exercise price and premium will
be agreed upon between the Portfolio and the transactions dealer, without the
intermediation of a third party such as a clearing corporation or exchange.  If
the transacting dealer fails to make or take delivery of the securities
underlying an option it has written, in accordance with the terms of that
option, the Portfolio would lose the premium paid for the option as well as any
anticipated benefit of the transaction.

COVERED CALL WRITING.  The Portfolio may write (i.e., sell) covered call options
on portfolio securities.  By doing so, the Portfolio would become obligated
during the terms of the option to deliver the securities underlying the option
should the option holder choose to exercise the option before the option's
termination date.  In return for the call it has written, the Portfolio will
receive from the purchaser (or option holder) a premium which is the price of
the option, less a commission charged by a broker.  The Portfolio will keep the
premium regardless of whether the option is exercised.  A call option is
"covered" if the Portfolio owns the security underlying the option it has
written or has an absolute or immediate right to acquire the security by holding
a call option on such security, or maintains a sufficient amount of cash, cash
equivalents or liquid securities to purchase the underlying security.  When the
Portfolio writes covered call options, it augments its income by the premiums
received and is thereby hedged to the extent of that amount against a decline in
the price of the underlying securities and the premiums received will offset a
portion of the potential loss incurred by the Portfolio if the securities
underlying the options are ultimately sold by the Portfolio at a loss.  However,
during the option period, the Portfolio has, in return for the premium on the
option, given up the opportunity for capital appreciation above the exercise
price should the market price of the underlying security increase, but has
retained the risk of loss should the price of the underlying security decline.
The size of premiums will fluctuate with varying market conditions.

COVERED PUT WRITING.  The Portfolio may write covered put options on portfolio
securities.  By doing so, the Portfolio incurs an obligation to buy the security
underlying the option from the purchaser of the put at the option's exercise
price at any time during the option period, at the purchaser's election (certain
listed and OTC options written by the Portfolio will be exercisable by the
purchaser only on a specific date).  Generally, a put option is "covered" if the
Portfolio maintains cash, or other liquid securities equal to the
exercise price of the option or if the Portfolio holds a put option on
the same underlying security with a similar or higher exercise price.


                                        5
<PAGE>


     The Portfolio may write put options to receive the premiums paid by
purchasers; when the Adviser wishes to purchase the security underlying the
option at a price lower than its current market price, in which case it will
write the covered put at an exercise price reflecting the lower purchase price
sought; and to close out long put option positions.

PURCHASE OF PUT AND CALL OPTIONS.  The Portfolio may purchase listed or OTC put
or call options on its portfolio securities in amounts exceeding no more than 5%
of its total assets.  When the Portfolio purchases a call option it acquires the
right to purchase a designated security at a designated price (the "exercise
price"), and when the Portfolio purchases a put option it acquires the right to
sell a designated security at the exercise price, in each case on or before a
specified date (the "termination date"), usually not more than nine months from
the date the option is issued.

     The Portfolio may purchase call options to close out a covered call
position or to protect against an increase in the price of a security it
anticipates purchasing.  The Portfolio may purchase put options on securities
which it holds in its portfolio only to protect itself against a decline in the
value of the security.  If the value of the underlying security were to fall
below the exercise price of the put purchased in an amount greater than the
premium paid for the option, the Portfolio would incur no additional loss.  The
Portfolio may also purchase put options to close out written put positions in a
manner similar to call option closing purchase transactions.

     The amount the Portfolio pays to purchase an option is called a "premium",
and the risk assumed by the Portfolio when it purchases an option is the loss of
this premium.  Because the price of an option tends to move with that of its
underlying security, if the Portfolio is to make a profit, the price of the
underlying security must change and the change must be sufficient to cover the
premium and commissions paid.  A price change in the security underlying the
option does not assure a profit since prices in the options market may not
always reflect such a change.


                                        6
<PAGE>

RISK FACTORS IN OPTIONS TRANSACTIONS.  The use of options also involves
additional risks.  Compared to the purchase or sale of futures contracts, the
purchase of call or put options involves less potential risk to a Portfolio
because the maximum amount of risk is the premium paid for the option.  The
writing of a call option generates a premium which may partially offset a
decline in the value of a Portfolio's portfolio assets.  By writing a call
option, the Portfolio becomes obligated to sell the underlying instrument, which
may have a value higher than the exercise price.  Conversely, the writing of a
put option generates a premium, but the Portfolio becomes obligated to purchase
the underlying instrument, which may have a value lower than the exercise price.
Thus, the loss incurred by a Portfolio in writing options may exceed the amount
of the premium received.

The effective use of options strategies is dependent, among other things, on a
Portfolio's ability to terminate options positions at a time when the portfolio
manager deems it desirable to do so.  Although a Portfolio will enter into
options positions only if the portfolio manager believes that a liquid secondary
market exists for such options, there is no assurance that the Portfolio will be
able to effect closing transactions at any particular time or at an acceptable
price.

A Portfolio's purchase or sale of put or call options will be based upon
predictions as to anticipated market trends and/or interest rate movements by
the portfolio manager, which could prove to be inaccurate.  Even if the
expectations of the portfolio manager are correct, there may be an imperfect
correlation between the change in the value of the options and of the
Portfolio's portfolio securities.

The writer of an option may have no control over when the underlying securities
must be sold, in the case of a call option, or purchased, in the case of a put
option; the writer may be assigned an exercise notice at any time prior to the
termination of the obligation.  Whether or not an option expires unexercised,
the writer retains the amount of the premium.  This amount, of course, may, in
the case of a covered call option, be offset by a decline in the market value of
the underlying security during the option period.  If a call option is
exercised, the writer experiences a profit or loss from the sale of the
underlying security.  If a put option is exercised, the writer must fulfill the
obligation to purchase the underlying security at the exercise price which will
usually exceed the then market value of the underlying security.

The writer of an option that wishes to terminate its obligation may effect a
"closing purchase transaction."  This is accomplished by buying an option of the
same series as the option previously written.  The effect of the purchase is
that the writer's position will be canceled by the clearing corporation.
However, a writer may not effect a closing purchase transaction after being
notified of the exercise of an option.  Likewise, an investor who is the holder
of an option may liquidate its position by effecting a "closing sale
transaction."  This is accomplished by selling an option of the same series as
the option previously purchased.  There is no guarantee that either a closing
purchase or a closing sale transaction can be effected.

Effecting a closing transaction in the case of a written call option will permit
the Portfolio to write another call option on the underlying security with
either a different exercise price or expiration date or both, in the case of a
written put option, will permit the Portfolio to write another put option to the
extent that the exercise price thereof is secured by depositing liquid assets.
Also, effecting a closing transaction will permit the cash or proceeds from the
concurrent sale of any securities subject to the option to be used for other
Portfolio investments.  If the Portfolio desires to sell a particular security
from its portfolio on which it has written a call option, it will effect a
closing transaction prior to or concurrent with the sale of the security.

A Portfolio will realize a profit from a closing transaction if the price of the
transaction is less than the premium received from writing the option or is more
than the premium paid to purchase the option; the Portfolio will realize a loss
from a closing transaction if the price of the transaction is more than the
premium received from writing the option or is less than the premium paid to
purchase the option.  Because increases in the market price of a call option
will generally reflect increases in the market price of the underlying security,
any loss resulting from the repurchase of a call option is likely to be offset
in whole or in part by appreciation of the underlying security owned by the
Portfolio.

An options position may be closed out only where there exists a secondary market
for an option of the same series.  If a secondary market does not exist, it
might not be possible to effect a closing transaction in particular options with
the result that the Portfolio would have to exercise the options in order to
realize any profit.  If the Portfolio is unable to effect a closing purchase
transaction in a secondary market, it will not be able to sell the underlying
security until the option expires or it delivers the underlying security upon
exercise.  Reasons for the absence of a liquid secondary market include the
following:  (1) there may be insufficient trading interest in certain options,
(2) restrictions may be imposed by an exchange on opening transactions or
closing transactions, or both, (3) trading halts, suspensions or other
restrictions may be imposed with respect to particular classes or series of
options or underlying securities, (4) unusual or unforeseen circumstances may
interrupt normal operation on an exchange, (5) the facilities of an exchange or
OCC may not at all times be adequate to handle current trading volume, or (6)
one or more exchange could, for economic or other reasons, decide or be
compelled at some future date to discontinue the trading of options (or a
particular class or series of options), in which event the secondary market on
that Exchange (or in that class or series of options) would cease to exist,
although outstanding options on that exchange that had been issued by OCC as a
result of trades on that exchange would continue to be exercisable in accordance
with their terms.

The Portfolios may purchase put options to hedge against a decline in the value
of their portfolios.  By using put options in this way, the Portfolios will
reduce any profit they might otherwise have realized in the underlying security
by the amount of the premium paid for the put option and by transaction costs.

The Portfolios may purchase call options to hedge against an increase in the 
price of securities that the Portfolios anticipate purchasing in the future. 
The premium paid for the call option plus any transaction costs will reduce 
the benefit, if any, realized by a Portfolio upon exercise of the option, 
and, unless the price of the underlying security rises sufficiently, the 
option may expire worthless.

Options may also be traded OTC ("OTC Options").  In an OTC trading environment,
many of the protections afforded to exchange participants will not be available.
For example, there are no daily price fluctuation limits, and adverse market
movements could therefore continue to an unlimited extent over a period of time.
The Portfolios may purchase or write OTC Options deemed creditworthy by the
Adviser.  OTC Options are illiquid and it may not be possible for the Portfolios
to dispose of such options they have purchased or terminate their obligations
under an option they have written at a time when the Adviser and portfolio
manager believe it would be advantageous to do so.  Accordingly, OTC Options are
subject to the Portfolios' limitation that a maximum of 15% of its net assets be
invested in illiquid securities.  In the event of the bankruptcy of the writer
of an OTC Option, the Portfolios could experience a loss of all or part of the
value of the option.

For a discussion regarding the special risks of foreign currency options, see
"Risks Associated with Foreign Currency Transactions," in this SAI.

PORTFOLIO TURNOVER

     The portfolio turnover rate for a year is the lesser of the value of the
purchases or sales for the year divided by the average monthly market value of
the Portfolio for the year, excluding U.S. Government securities and securities
with maturities of one year or less.  The portfolio turnover rate for a year is
calculated by dividing the lesser of sales or the average monthly value of the
Portfolio's portfolio purchases of portfolio securities during that year by
securities, excluding money market instruments.  The rate of portfolio turnover
will not be a limiting factor when the Portfolio deems it appropriate to
purchase or sell securities for the Portfolio.  However, the U.S. federal tax
requirement that the Portfolio derive less than 30% of its gross income from the
sale or disposition of securities held less than three months may limit the
Portfolio's ability to dispose of its securities.  See "Taxes."

SECURITIES LENDING

     The Portfolio may lend its investment securities to qualified institutional
investors who need to borrow securities in order to complete certain
transactions, such as covering short sales, avoiding failures to deliver
securities or completing arbitrage operations.  By lending its investment
securities, the Portfolio attempts to increase its net investment income through
the receipt of interest on the loan.  Any gain or loss in the market price of
the securities loaned that might occur during the term of the loan would be for
the account of the Portfolio.  The Portfolio may lend its investment securities
to qualified brokers, dealers, domestic and foreign banks or other financial
institutions, so long as the terms, structure and the aggregate amount of such
loans are not inconsistent with the Investment Company Act of 1940, as amended
(the "1940 Act"), or the Rules and Regulations or interpretations of the
Securities and Exchange Commission (the "Commission") thereunder, which
currently require that (a) the borrower pledge and maintain with the Portfolio
collateral consisting of cash, an irrevocable letter of credit issued by a
domestic U.S. bank, or securities issued or guaranteed by the United States
Government having a value at all times not less than 100% of the value of the
securities loaned, (b) the borrower add to such collateral whenever the price of
the securities loaned rises (i.e., the borrower "marks to the market" on a daily
basis), (c) the loan be made subject to termination by the Portfolio at any
time, and (d) the Portfolio receive reasonable interest on the loan (which may
include the Portfolio investing any cash collateral in interest bearing
short-term investments), any distributions on the loaned securities and any
increase in their market value.  There may be risks of delay in recovery of the
securities or even loss of rights in the collateral should the borrower of the
securities fail financially.  However, loans will only be made to borrowers
deemed by the Advisor to be of good standing and when, in the judgment of the
Advisor, the consideration which can be earned currently from such securities
loans justifies the attendant risk. All relevant facts and circumstances,
including the creditworthiness of the broker, dealer or institution, will be
considered in making decisions with respect to the lending of securities,
subject to review by the Board of Directors of the Fund.

     At the present time, the staff of the Commission does not object if an
investment company pays reasonable negotiated fees in connection with loaned
securities, so long as such fees are set forth in a written contract and
approved by the investment company's


                                        7
<PAGE>


Board of Directors.  Voting rights may pass with the loaned securities, provided
that if a material event occurs affecting a security on loan, the loan must be
called and the securities voted.

SHORT SALES

     The Portfolio may from time to time sell securities short without 
limitation but consistent with applicable legal requirements, although at 
present the Portfolio does not intend to sell securities short.  A short sale 
is a transaction in which the Portfolio would sell securities it owns or has 
the right to acquire at no added cost (i.e., "against the box") or does not 
own (but has borrowed) in anticipation of a decline in the market price of 
the securities.  When the Portfolio makes a short sale of borrowed 
securities, the proceeds it receives from the sale will be held on behalf of 
a broker until the Portfolio replaces the borrowed securities.  To deliver 
the securities to the buyer, the Portfolio will need to arrange through a 
broker to borrow the securities and, in so doing, the Portfolio will become 
obligated to replace the securities borrowed at their market price at the 
time of replacement, whatever that price may be.  The Portfolio may have to 
pay a premium to borrow the securities and must pay any dividends or interest 
payable on the securities until they are replaced.

     The Portfolio's obligation to replace the securities borrowed in connection
with a short sale will be secured by collateral deposited with the broker that
consists of cash or liquid securities. In addition, if the short sale is not 
"against the box," the Portfolio will place in a segregated account with its 
custodian, or designated sub-custodian, an amount of cash or liquid securities 
equal to the difference, if any, between the current market value of the 
securities sold short and any cash or liquid securities deposited as collateral
with the broker in connection with the short sale. Until it replaces the 
borrowed securities, the Portfolio will maintain the segregated account 
daily at a level so that the amount deposited in the account plus the amount
deposited with the broker will equal the current market value of the securities
sold short.

     Short sales by the Portfolio involve certain risks and special
considerations.  Possible losses from short sales differ from losses that could
be incurred from a purchase of a security, because losses from short sales may
be unlimited, whereas losses from purchases can equal only the total amount
invested.

U.S. GOVERNMENT SECURITIES

     The term "U.S. Government securities" refers to a variety of securities
which are issued or guaranteed by the U.S. Government, and by various
instrumentalities which have been established or sponsored by the U.S.
Government.

     U.S. Treasury securities are backed by the "full faith and credit" of the
United States. Securities issued or guaranteed by Federal agencies and U.S.
Government sponsored instrumentalities may or may not be backed by the full
faith and credit of the United States.  In the case of securities not backed by
the full faith and credit of the United States, the investor must look
principally to the agency or instrumentality issuing or guaranteeing the
obligation for ultimate repayment, and may not be able to assert a claim against
the United States itself in the event the agency or instrumentality does not
meet its commitment. Agencies which are backed by the full faith and credit of
the United States include the Export-Import Bank, Farmers Home Administration,
Federal Financing Bank, and others.  Certain agencies and instrumentalities,
such as the Government National Mortgage Associates, are, in effect, backed by
the full faith and credit of the United States through provisions in their
charters that they may make "indefinite and unlimited" drawings on the Treasury,
if needed to service debt.  Debt from certain other agencies and
instrumentalities, including the Federal Home Loan Bank and Federal National
Mortgage Association, are not guaranteed by the United States, but those
institutions are protected by the discretionary authority for the U.S. Treasury
to purchase certain amounts of their securities to assist the institution in
meeting its debt obligations.  However, the U.S. Treasury has no lawful
obligation to assume the financial liabilities of these agencies or others.
Finally, other agencies and instrumentalities, such as the Farm Credit System
and the Federal Home Loan Mortgage Corporation, are federally chartered
institutions under Government supervision, but their debt securities are backed
only by the creditworthiness of those institutions, not the U.S. Government.

     Some of the U.S. Government agencies that issue or guarantee securities
include the Export-Import Bank of the United States, Farmers Home
Administration, Federal Housing Administration, Maritime Administration, Small
Business Administration, and the Tennessee Valley Authority.

     An instrumentality of the U.S. Government is a Government agency organized
under Federal charter with Government supervision.  Instrumentalities issuing or
guaranteeing securities include, among others, Federal Home Loan Banks, the
Federal Land Banks, Central Bank for Cooperatives, Federal Immediate Credit
Banks, and the Federal National Mortgage Association.

                                      TAXES

     The following is only a summary of certain additional federal tax
considerations generally affecting the Fund and its shareholders that are not
described in the Prospectus.  No attempt is made to present a detailed
explanation of the federal, state or local tax treatment of the Fund or its
shareholders, and the discussion here and in the Fund's Prospectus is not
intended as a substitute for careful tax planning.

     The following discussion of federal income tax consequences is based on the
Internal Revenue Code of 1986, as amended (the "Code") and the regulations
issued thereunder as in effect on the date of this Statement of Additional
Information.  New legislation, as well as administrative changes or court
decisions, may significantly change the conclusions expressed herein, and may
have a retroactive effect with respect to the transactions contemplated herein.

     Each Portfolio within the Fund is generally treated as a separate
corporation for federal income tax purposes, and thus the provisions of the Code
generally will be applied to each Portfolio separately, rather than to the Fund
as a whole.

              GENERAL REGULATED INVESTMENT COMPANY QUALIFICATION

     The Portfolio intends to qualify and elect to be treated for each taxable
year as a regulated investment company ("RIC") under Subchapter M of the Code.
Accordingly, the Portfolio must, among other things, (a) derive at least 90% of
its gross income each taxable year from dividends, interest, payments with
respect to securities loans, gains from the sale or other disposition of stock,

                                        8
<PAGE>


securities or foreign currencies, and certain other related income, including,
generally, certain gains from options, futures and forward contracts; (b) derive
less than 30% of its gross income each taxable year from the sale or other
disposition of the following items if held less than three months (A) stock or
securities, (B) options, futures or forward contracts (other than options,
futures or forward contracts on foreign currencies), and (C) foreign currencies
(or options, futures, or forward contracts on foreign currencies) that are not
directly related to the Portfolio's principal business of investing in stocks or
securities (or options or futures with respect to stock or securities) (the
"short-short test"); and (c) diversify its holdings so that, at the end of each
fiscal quarter of the Portfolio's taxable year, (i) at least 50% of the market
value of the Portfolio's total assets is represented by cash and cash items,
United States Government securities, securities of other RICs, and other
securities, with such other securities limited, in respect to any one issuer, to
an amount not greater than 5% of the value of the Portfolio's total assets or
10% of the outstanding voting securities of such issuer, and (ii) not more than
25% of the value of its total assets is invested in the securities (other than
United States Government securities or securities of other RICs) of any one
issuer or two or more issuers which the Portfolio controls and which are engaged
in the same, similar, or related trades or business.  For purposes of the 90% of
gross income requirement described above, foreign currency gains which are not
directly related to the Portfolio's principal business of investing in stock or
securities (or options or futures with respect to stock or securities) may be
excluded from income that qualifies under the 90% requirement.

     In addition to the requirements described above, in order to qualify as a
RIC, the Portfolio must distribute at least 90% of its net investment income
(which generally includes dividends, taxable interest, and the excess of net
short-term capital gains over net long-term capital losses less operating
expenses) and at least 90% of its net tax-exempt interest income, for each tax
year, if any, to its shareholders. If the Portfolio meets all of the RIC
requirements, it will not be subject to federal income tax on any of its net
investment income or capital gains that it distributes to shareholders.

     If the Portfolio fails to qualify as a RIC for any year, all of its income
will be subject to tax at corporate rates, and its distributions (including
capital gains distributions) will be taxable as ordinary income dividends to its
shareholders to the extent of the Portfolio's current and accumulated earnings
and profits, and will be eligible for the corporate dividends received deduction
for corporate shareholders.

          GENERAL TAX TREATMENT OF QUALIFYING RICs AND SHAREHOLDERS

     The Portfolio will decide whether to distribute or to retain all or part of
any net capital gains (the excess of net long-term capital gains over net short-
term capital losses) in any year for reinvestment.  If any such gains are
retained, the Portfolio will pay federal income tax thereon, and, if the
Portfolio makes an election, the shareholders will include such undistributed
gains in their income, will increase their basis in Portfolio shares by 65% of
the amount included in their income and will be able to claim their share of the
tax paid by the Portfolio as a refundable credit.

     A gain or loss realized by a shareholder on the sale, exchange or exemption
of shares of the Portfolio held as a capital asset will be capital gain or loss,
and such gain or loss will be long-term if the holding period for the shares
exceeds one year, and otherwise will be short-term.  Any loss realized on a
sale, exchange, or redemption of shares of the Portfolio will be disallowed to
the extent the shares disposed of are replaced within the 61-day period
beginning 30 days before and ending 30 days after the shares are disposed of.
Any loss realized by a shareholder on the disposition of shares held 6 months or
less is treated as a long-term capital loss to the extent of any distributions
of net long-term capital gains received by the shareholder with respect to such
shares or any inclusion of undistributed capital gain with respect to such
shares.

     The conversion of Class A shares to Class B shares should not be a taxable
event to the shareholder.

     The Portfolio will generally be subject to a nondeductible 4% federal
excise tax to the extent it fails to distribute by the end of any calendar year
at least 98% of its ordinary income for that year and 98% of its capital gain
net income (the excess of short- and long-term capital gains over short- and
long-term capital losses) for the one-year period ending on October 31 of that
year, plus certain other amounts.

     The Portfolio is required by federal law to withhold 31% of reportable
payments (which may include dividends, capital gains distributions, and
redemptions) paid to shareholders who have not certified on the Account
Registration Form or on a separate form supplied by the Portfolio, that the
Social Security or Taxpayer Identification Number provided is correct and that
the shareholder is exempt from backup withholding or is not currently subject to
backup withholding.

     For certain transactions, the Portfolio is required for federal income tax
purposes to recognize as gain or loss its net unrealized gains and losses on
forward currency and futures contracts as of the end of each taxable year, as
well as those actually realized during the year.  In most cases, any such gain
or loss recognized with respect to a regulated futures contract is considered to
be 60% long-term capital gain or loss and 40% short-term capital gain or loss,
without regard to the holding period of the contract.  Realized gain or loss
attributable to a foreign currency forward contract is treated as 100% ordinary
income.  Furthermore, foreign


                                        9
<PAGE>




currency futures contracts which are intended to hedge against a change in the
value of securities held by the Portfolio may affect the holding period of such
securities and, consequently, the nature of the gain or loss on such securities
upon disposition.

     As discussed above, in order for the Portfolio to continue to qualify for
federal income tax treatment as a RIC, at least 90% of its gross income for a
taxable year must be derived from certain qualifying income, including
dividends, interest, income derived from loans of securities, and gains from the
sale or other disposition of stock, securities or foreign currencies, or other
related income, including gains from options, futures and forward contracts,
derived with respect to its business of investing in stock, securities or
currencies.  Any net gain realized from the closing out of futures contracts
will therefore generally be qualifying income for purposes of the 90%
requirement.  Qualification as a RIC also requires that less than 30% of the
Portfolio's gross income be derived from the sale or other disposition of stock,
securities, options, futures or forward contracts (including certain foreign
currencies not directly related to the Fund's business of investing in stock or
securities) held less than three months.  In order to avoid realizing excessive
gains on futures contracts held less than three months, the Portfolio may be
required to defer the closing out of futures contracts beyond the time when it
would otherwise be advantageous to do so.

     Short sales engaged in by the Portfolio may reduce the holding property
held by the Portfolio which is substantially identical to the property sold
short.  This rule may make it more difficult for the Portfolio to satisfy the
short-short test.  This rule may also have the effect of converting capital
gains recognized by the Portfolio from long-term to short-term as well as
converting capital losses recognized by the Portfolio from short-term to long-
term.

           SPECIAL TAX CONSIDERATIONS RELATING TO FOREIGN INVESTMENTS

     Gains or losses attributable to foreign currency contracts, or to
fluctuations in exchange rates that occur between the time the Portfolio accrues
interest or other receivables or accrues expenses or other liabilities
denominated in a foreign currency and the time the Portfolio actually collects
such receivables or pays such liabilities are treated as ordinary income or
ordinary loss to the Portfolio.  Similarly, gains or losses on disposition of
debt securities denominated in a foreign currency attributable to fluctuations
in the value of the foreign currency between the date of acquisition of the
security and the date of disposition also are treated as ordinary gain or loss
to the Portfolio.  These gains or losses increase or decrease the amount of the
Portfolio's net investment income available to be distributed to its
shareholders as ordinary income.

     It is expected that the Portfolio will be subject to foreign withholding
taxes with respect to its dividend and interest income from foreign countries,
and the Portfolio may be subject to foreign income taxes with respect to other
income.  So long as more than 50% in value of the Portfolio's total assets at
the close of the taxable year consists of stock or securities of foreign
corporations, the Portfolio may elect to treat certain foreign income taxes
imposed on it for United States federal income tax purposes as paid directly by
its shareholders.  The Portfolio will make such an election only if it deems it
to be in the best interest of its shareholders and will notify shareholders in
writing each year if it makes an election and of the amount of foreign income
taxes, if any, to be treated as paid by the shareholders.  If the Portfolio
makes the election, shareholders will be required to include in income their
proportionate shares of the amount of foreign income taxes treated as imposed on
the Portfolio and will be entitled to claim either a credit (subject to the
limitations discussed below) or, if they itemize deductions, a deduction, for
their shares of the foreign income taxes in computing their federal income tax
liability.

     Shareholders who choose to utilize a credit (rather than a deduction) for
foreign taxes will be subject to a number of complex limitations regarding the
availability and utilization of the credit.  Because of these limitations,
shareholders may be unable to claim a credit for the full amount of their
proportionate shares of the foreign income taxes paid by the Portfolio.
Shareholders are urged to consult their tax advisors regarding the application
of these rules to their particular circumstances.


                         TAXES AND FOREIGN SHAREHOLDERS

     Taxation of a shareholder who, as to the United States, is a nonresident
alien individual, a foreign trust or estate, a foreign corporation, or a foreign
partnership ("Foreign Shareholder") depends on whether the income from the
Portfolio is "effectively connected" with a U.S. trade or business carried on by
such shareholder.

     If the income from the Portfolio is not effectively connected with a U.S.
trade or business carried on by a Foreign Shareholder, distributions of net
investment income plus the excess of net  short-term capital gains over net
long-term capital losses will be subject to U.S. withholding tax at the rate of
30% (or such lower treaty rate as may be applicable) upon the gross amount of
the dividend.  Furthermore, Foreign Shareholders will generally be exempt from
U.S. federal income tax on gains realized on the


                                       10
<PAGE>


sale of shares of the Portfolio, distributions of net long-term capital gains,
and amounts retained by the Fund which are designated as undistributed capital
gains.

     If the income from the Portfolio is effectively connected with a U.S. trade
or business carried on by a Foreign Shareholder, then distributions from the
Portfolio and any gains realized upon the sale of shares of the Portfolio, will
be subject to U.S. federal income tax at the rates applicable to U.S. citizens
and residents or domestic corporations.

     The Portfolio may be required to withhold U.S. federal income tax on
distributions that are otherwise exempt from withholding tax (or taxable at a
reduced treaty rate) unless the Foreign Shareholder complies with Internal
Revenue Service certification requirements.

     The tax consequences to a Foreign Shareholder entitled to claim the
benefits of an applicable tax treaty may differ from those described here.
Furthermore, Foreign Shareholders are strongly urged to consult their own tax
advisors with respect to the particular tax consequences to them of an
investment in the Portfolio, including the potential application of the
provisions of the Foreign Investment in Real Estate Property Tax Act of 1980, as
amended.


                               PURCHASE OF SHARES

     The following supplements the Purchase of Shares section in the Prospectus.

     The purchase price of shares of the Portfolio is the net asset value next
determined after the order is received.  An order received prior to the regular
close of the New York Stock Exchange (the "NYSE") will be executed at the price
computed on the date of receipt; and an order received after the regular close
of the NYSE will be executed at the price computed on the next day the NYSE is
open as long as the Fund's transfer agent receives payment by check or in
Federal Funds prior to the regular close of the NYSE on such day.  Shares of the
Fund may be purchased on any day the NYSE is open.  The NYSE will be closed on
the following days:  New Year's Day, Presidents' Day, Good Friday, Memorial Day,
Independence Day, Labor Day, Thanksgiving Day and Christmas Day and on the
preceding Friday or subsequent Monday when one of these holidays falls on a
Saturday or Sunday, respectively.

     The Portfolio reserves the right in its sole discretion (i) to suspend the
offering of its shares, (ii) to reject purchase orders when in the judgment of
management such rejection is in the best interest of the Fund, and (iii) to
reduce or waive the minimum for initial and subsequent investments for certain
fiduciary accounts such as employee benefit plans or under circumstances where
certain economies can be achieved in sales of the Portfolio's shares.




                              REDEMPTION OF SHARES

     The following supplements the Redemption of Shares section in the
Prospectus.

     The Portfolio may suspend redemption privileges or postpone the date of
payment (i) during any period that the NYSE is closed, or trading on the NYSE is
restricted as determined by the Commission, (ii) during any period when an
emergency exists as defined by the rules of the Commission as a result of which
it is not reasonably practicable for the Portfolio to dispose of securities
owned by it, or fairly to determine the value of its assets, and (iii) for such
other periods as the Commission may permit.

     No charge is made by the Portfolio for redemptions.  Any redemption may be
more or less than the shareholder's cost depending on the market value of the
securities held by the Portfolio.

     To protect your account and the Fund from fraud, signature guarantees are
required for certain redemptions.  Signature guarantees enable the Fund to
verify the identity of the person who has authorized a redemption from your
account.  Signature guarantees are required in connection with:  (1) all
redemptions, regardless of the amount involved, when the proceeds are to be paid
to someone other than the registered owner(s) and/or registered address; and
(2) share transfer requests.

     A guarantor must be a bank, a trust company, a member firm of a domestic
stock exchange, or a foreign branch of any of the foregoing.  Notaries public
are not acceptable guarantors.


                                       11
<PAGE>


     The signature guarantees must appear either:  (1) on the written request
for redemption; (2) on a separate instrument for assignment ("stock power")
which should specify the total number of shares to be redeemed; or (3) on all
stock certificates tendered for redemption and, if shares held by the Fund are
also being redeemed, on the letter or stock power.


                              SHAREHOLDER SERVICES

     The following supplements the Shareholder Services section in the
Prospectus.

EXCHANGE FEATURES

     Shares of the Portfolio of the Fund may be exchanged for shares of any
other available Portfolio (other than the International Equity Portfolio, which
is closed to new investors).  In exchanging for shares of a Portfolio with more
than one class, the class of shares a shareholder receives in exchange will be
determined in the same manner as any other purchase of shares and will not be
based on the class of shares surrendered for the exchange.  Consequently, the
same minimum initial investment and minimum account size for determining the
class of shares received in the exchange will apply.

     Any such exchange will be based on the respective net asset values of the
shares involved.  There is no sales commission or sales charge of any kind.  
Before making an exchange, a shareholder should consider the investment 
objectives of the Portfolio to be purchased.

     Exchange requests may be made either by mail or telephone.  Exchange
requests by mail should be sent to Morgan Stanley Institutional Fund, Inc., P.O.
Box 2798, Boston, Massachusetts 02208-2798. Telephone exchanges will be accepted
only if the certificates for the shares to be exchanged are held by the Fund for
the account of the shareholder and the registration of the two accounts will be
identical.  Requests for exchanges received prior to 4:00 p.m. (Eastern Time)
will be processed as of the close of business on the same day.  Requests
received after these times will be processed on the next business day.
Exchanges may be subject to limitations as to amounts or frequency, and to other
restrictions established by the Board of Directors to assure that such exchanges
do not disadvantage the Fund and its shareholders.

     For federal income tax purposes an exchange between Portfolios is a taxable
event for shareholders subject to tax, and, accordingly, a gain or loss may be
realized.  The exchange privilege may be modified or terminated by the Fund at
any time upon 60 days notice to shareholders.

TRANSFER OF SHARES

     Shareholders may transfer shares of the Portfolio to another person by
making a written request to the Fund.  The request should clearly identify the
account and number of shares to be transferred, and include the signature of all
registered owners and all stock certificates, if any, which are subject to the
transfer.  The signature on the letter of request, the stock certificate or any
stock power must be guaranteed in the same manner as described under "Redemption
of Shares."  As in the case of redemptions, the written request must be received
in good order before any transfer can be made.  Transferring shares may affect
the eligibility of an account for a given class of the Portfolio's shares and
may result in involuntary conversion or redemption of such shares.


                             INVESTMENT LIMITATIONS

     The Portfolio has adopted the following restrictions which are fundamental
policies and may not be changed without the approval of the lesser of:  (1) at
least 67% of the voting securities of the Portfolio present at a meeting if the
holders of more than 50% of the outstanding voting securities of the Portfolio
are present or represented by proxy, or (2) more than 50% of the outstanding
voting securities of the Portfolio.  The Portfolio will not:

     (1)  purchase or sell physical commodities unless acquired as a result of
ownership of securities or other instruments (except this shall not prevent the
Portfolio from purchasing or selling options or futures contracts or from
investing in securities or other instruments backed by physical commodities);

     (2)  purchase or sell real estate, although it may purchase and sell
securities of companies that deal in real estate and may purchase and sell
securities that are secured by interests in real estate;


                                       12
<PAGE>

     (3)  lend any security or make any other loan if, as a result, more than 33
1/3% of its total assets would be lent to other parties, but this limitation
does not apply to purchases of debt securities or repurchase agreements;

     (4)  issue senior securities;




     (5)  borrow, except the Portfolio may: borrow from banks in amounts up to
33 1/3% of its total assets (including the amount borrowed) less liabilities
in accordance with its investment objective and policies;

     (6)  underwrite securities issued by others, except to the extent that the
Portfolio may be considered an underwriter within the meaning of the 1933 Act in
the disposition of restricted securities;

     (7)  acquire any securities of companies within one industry if, as a 
result of such acquisition, more than 25% of the value of the Portfolio's 
total assets would be invested in securities of companies within such 
industry; provided, however, that there shall be no limitation on the purchase 
of securities of companies in the technology or technology related industries, 
or on the purchase of obligations issued or guaranteed by the U.S. Government, 
its agencies or instrumentalities; and

     (8)  write or acquire options or interests in oil, gas or other mineral
exploration or development programs.

     With respect to fundamental limitation (7) above, the Fund will determine 
industry concentration in accordance with the classifications of industries
based on the Industry Numbers from the Standard Industrial Classification Manual
as prepared by the Office of Management and Budget, except that companies in 
the technology and technology related industries will be deemed part of one 
industry.

     The Portfolio will diversify its holdings so that, at the close of each
quarter of its taxable year, (i) at least 50% of the market value of the
Portfolio's total assets is represented by cash (including cash items and
receivables), U.S. Government securities, and other securities, with such other
securities limited, in respect of any one issuer, for purposes of this
calculation to an amount not greater than 5% of the value of the Portfolio's
total assets and 10% of the outstanding voting securities of such issuer, and
(ii) not more than 25% of the value of its total assets is invested in the
securities of any one issuer (other than U.S. Government securities);

     In addition, the Portfolio has adopted non-fundamental investment
limitations as stated below and in the Prospectus.  Such limitations may be
changed without shareholder approval.  The Portfolio will not:

     (1)  purchase on margin or sell short, except that the Portfolio may enter
into short sales in accordance with its investment objective and policies;

     (2)  purchase or retain securities of an issuer if those Officers and
Directors of the Fund or its investment adviser owning more than 1/2 of 1% of
such securities together own more than 5% of such securities;

     (3)  pledge, mortgage, or hypothecate any of its assets to an extent
greater than 10% of its total assets at fair market value;

     (4)  invest for the purpose of exercising control over management of any
company;

     (5)  invest its assets in securities of any investment company, except as
permitted by the 1940 Act or the rules, regulations, interpretations or orders
of the Commission and its staff thereunder;

     (6)  invest in real estate limited partnership interests;



     (7)  make loans except (i) by purchasing bonds, debentures or similar
obligations (including repurchase agreements, subject to the limitations as
described in the Prospectus) that are publicly distributed, and (ii) by lending
its portfolio securities to

                                       13
<PAGE>


banks, brokers, dealers and other financial institutions so long as such loans
are not inconsistent with the 1940 Act or the Rules and Regulations or
interpretations of the Commission thereunder;

     (8) purchase puts, calls, straddles, spreads and any combination thereof
if for any reason thereof the value of its aggregate investment in such classes
of securities will exceed 5% of its total assets, except that the Portfolio may
enter into option transactions to the extent that not more than 5% of the
Portfolio's total assets are required as deposits to secure obligations under
options and not more than 20% of its total assets are invested in options,
futures contracts and options on futures contracts at any time.

     (9) borrow money, except from banks for extraordinary or emergency
purposes, and then only in amounts up to 10% of the value of the Portfolio's
total assets, taken at cost at the time of borrowing, or purchase securities
while borrowings exceed 5% of its total assets;

     (10) invest in fixed time deposits with a duration of over seven calendar
days or invest in fixed time deposits with a duration of from two business days
to seven calendar days if more than 10% of the Portfolio's total assets would
be invested in these deposits.

     The percentage limitations contained in these restrictions apply at the
time of purchase of securities.


                  DETERMINING MATURITIES OF CERTAIN INSTRUMENTS

     Generally, the maturity of a portfolio instrument shall be deemed to be the
period remaining until the date noted on the face of the instrument as the date
on which the principal amount must be paid, or in the case of an instrument
called for redemption, the date on which the redemption payment must be made.
However, instruments having variable or floating interest rates or demand
features may be deemed to have remaining maturities as follows:  (a) a
Government Obligation with a variable rate of interest readjusted no less
frequently than annually may be deemed to have a maturity equal to the period
remaining until the next readjustment of the interest rate; (b) an instrument
with a variable rate of interest, the principal amount of which is scheduled on
the face of the instrument to be paid in one year or less, may be deemed to have
a maturity equal to the period remaining until the next readjustment of the
interest rate; (c) an instrument with a variable rate of interest that is
subject to a demand feature may be deemed to have a maturity equal to the longer
of the period remaining until the next readjustment of the interest rate or the
period remaining until the principal amount can be recovered through demand;
(d) an instrument with a floating rate of interest that is subject to a demand
feature may be deemed to have a maturity equal to the period remaining until the
principal amount can be recovered through demand; and (e) a repurchase agreement
may be deemed to have a maturity equal to the period remaining until the date on
which the repurchase of the underlying securities is scheduled to occur, or
where no date is specified, but the agreement is subject to demand, the notice
period applicable to a demand for the repurchase of the securities.


                             MANAGEMENT OF THE FUND

OFFICERS AND DIRECTORS

     The Fund's officers, under the supervision of the Board of Directors,
manage the day-to-day operations of the Fund.  The Directors set broad policies
for the Fund and choose its officers.  Three Directors and all of the officers
of the Fund are directors, officers or employees of the Fund's adviser,
distributor or administrative services provider.  Directors and officers of the
Fund are also directors and officers of some or all of the other investment
companies managed, administered, advised or distributed by Morgan Stanley Asset
Management Inc. or its affiliates.  The other Directors have no affiliation with
the Fund's adviser, distributor or administrative services provider.  A list of
the Directors and officers of the Fund and a brief statement of their present
positions and principal occupations during the past five years is set forth
below:




                                       14
<PAGE>


 Name, Address and Date                         Principal Occupation During
      of Birth              Postion With Fund         Past Five Years
 ----------------------     -----------------   -----------------------------

 Barton M. Biggs*           Chairman and       Chairman, Director and Managing
 1221 Avenue of the         Director           Director of Morgan Stanley Asset
 Americas                                      Management Inc. and Morgan
 New York, NY 10020                            Stanley Asset Management Limited;
 11/26/32                                      Managing Director of Morgan 
                                               Stanley & Co. Incorporated;
                                               Director of Morgan Stanley Group
                                               Inc.; Member of Investment
                                               Advisory Counsel of the Thailand
                                               Fund; Director of the Rand
                                               McNally Company; Member of the
                                               Yale Development Board; Chairman
                                               and Director of 16 U.S.
                                               registered investment companies
                                               managed by Morgan Stanley Asset
                                               Management Inc.

 Warren J. Olsen*           Director and       Principal of Morgan Stanley &
 1221 Avenue of the         President          Co. Incorporated and of Morgan 
 Americas                                      Stanley Asset Management Inc.; 
 New York, NY 10020                            President and Director of 16 U.S.
 12/21/56                                      registered investment companies
                                               managed by Morgan Stanley Asset
                                               Management Inc.

 John D. Barrett, II        Director           Chairman and Director of Barrett
 521 Fifth Avenue                              Associates, Inc. (investment
 New York, NY 10135                            counseling); Director of the
 8/21/35                                       Ashforth Company (real estate);
                                               Director of the Morgan Stanley
                                               Fund, Inc., PCS Cash Fund, Inc.
                                               and Morgan Stanley Universal
                                               Funds, Inc.

 Gerard E. Jones            Director           Partner in Richards & O'Neil LLP
 43 Arch Street                                (law firm); Director of the
 Greenwich, CT 06830                           Morgan Stanley Fund, Inc., 
 1/23/37                                       PCS Cash Fund, Inc. and
                                               Morgan Stanley Universal Funds,
                                               Inc.

 Andrew McNally IV          Director           Chairman and Chief Executive
 8255 North Central                            Officer of Rand McNally
 Park Avenue                                   (publication); Director of
 Skokie, IL 60076                              Allendale Insurance Co., Mercury
 11/11/39                                      Finance (consumer finance);
                                               Zenith Electronics, Hubbell,
                                               Inc. (industrial electronics);
                                               Director of the Morgan Stanley
                                               Fund, Inc., PCS Cash Fund, Inc.
                                               and Morgan Stanley
                                               Universal Funds, Inc.

 Samuel T. Reeves           Director           Chairman of the Board and CEO,
 8211 North                                    Pinacle L.L.C. (investment
 Fresno Street                                 firm); Director, Pacific Gas and
 Fresno, CA 93720                              Electric and PG&E Enterprises
 7/28/34                                       (utilities); Director of the
                                               Morgan Stanley Fund, Inc.,
                                               PCS Cash Fund, Inc. and
                                               Morgan Stanley Universal 
                                               Funds, Inc.

 Fergus Reid                Director           Chairman and Chief Executive
 85 Charles Colman Blvd                        Officer of LumeLite Corporation
 Pawling, NY 12564                             (injection molding firm);
 8/12/32                                       Trustee and Director of Vista
                                               Mutual Fund Group; Director of
                                               the Morgan Stanley Fund, Inc.
                                               PCS Cash Fund, Inc. and
                                               Morgan Stanley Universal 
                                               Funds, Inc.
   
 Frederick O. Robertshaw    Director           Of Counsel, Copple,
 2800 North Central Avenue                     Chamberlin & Boehm, P.C.;
 Phoenix, AZ 85004                             Formerly, Of Counsel, Bryan,
 1/24/34                                       Cave; (law firms); Director of
                                               the Morgan Stanley Fund, Inc.,
                                               PCS Cash Fund, Inc. and 
                                               Morgan Stanley Universal
                                               Funds, Inc.
                                               
    

                                  15

<PAGE>

 Name, Address and Date                        Principal Occupation During
        of Birth           Postion with Fund         Past Five Years
 ----------------------    -----------------   -----------------------------
   
    
 James W. Grisham*          Vice President     Principal of Morgan Stanley &
 1221 Avenue of the                            Co., Inc. and of Morgan Stanley
 Americas                                      Asset Management Inc.; Vice
 New York, NY 10020                            President of 16 U.S. registered
 10/24/41                                      investment companies managed by
                                               Morgan Stanley Asset Management
                                               Inc.
   
 Michael F. Klein*          Vice President     Principal of Morgan Stanley
 1221 Avenue of the Americas                   Asset Management Inc.; Officer
 New York, NY 10020                            of various investment 
 12/12/58                                      companies managed by Morgan 
                                               Stanley Asset Management Inc.
                                               Previously practiced law with
                                               the New York law 
                                               firm of Rogers & Wells.
    
 Harold J. Schaaff, Jr.*    Vice President     Principal of Morgan Stanley &
 1221 Avenue of the                            Co. and of Morgan Stanley Asset
 Americas                                      Management Inc.; General Counsel
 New York, NY 10020                            and Secretary of Morgan Stanley
 6/10/60                                       Asset Management Inc.; Vice
                                               President of 16 U.S. registered
                                               investment companies managed by
                                               Morgan Stanley Asset Management
                                               Inc.

 Joseph P. Stadler*         Vice President     Vice President of Morgan Stanley
 1221 Avenue of the                            & Co. Inc. and Morgan Stanley
 Americas                                      Asset Management Inc.;
 New York, NY 10020                            Previously with Price Waterhouse
 6/7/54                                        LLP (accounting); Vice President
                                               of 16 U.S. registered investment
                                               companies managed by Morgan
                                               Stanley Asset Management Inc.

 Valerie Y. Lewis*          Secretary          Vice President of Morgan Stanley
 1221 Avenue of the                            & Co. Inc. and Morgan Stanely
 Americas                                      Asset Management Inc.; 
 New York, NY 10020                            Previously with Citicorp
 3/26/56                                       (banking); Secretary of 16 U.S.
                                               registered investment companies
                                               managed by Morgan Stanley Asset
                                               Management Inc.

 Karl O. Hartmann           Assistant          Senior Vice President, Secretary
 73 Tremont Street          Secretary          and General Counsel of Chase
 Boston, MA 02108-3913                         Global Funds Services Company;
 3/7/55                                        Previously, Leland, O'Brien,
                                               Rubinstein Associates, Inc.
                                               (investments).
   
 James R. Rooney            Treasurer          Vice President, Director of 
 73 Tremont Street                             Fund Administration and  
 Boston, MA 02108-3913                         Compliance Services, Chase 
 10/21/58                                      Global Funds Services Company;
                                               Officer of various investment
                                               companies managed by Morgan
                                               Stanley Asset Management Inc.;
                                               Previously with Scudder, Stevens
                                               & Clark, Inc. (investments) and
                                               Ernst & Young LLP (accounting);
                                               Treasurer of 16 U.S. registered
                                               investment companies managed by
                                               Morgan Stanley Asset Management
                                               Inc.
    
   
 Joanna Haigney             Assistant          Manager of Fund Administration 
 73 Tremont Street          Treasurer          and Compliance Services,
 Boston, MA 02108-3913                         Chase Global Funds Services
 10/10/66                                      Company; Previously with Coopers
                                               & Lybrand LLP; Assistant
                                               Treasurer of 16 U.S. registered
                                               investment companies managed by
                                               Morgan Stanley Asset Management
                                               Inc.
    

_______

*    "Interested Person" within the meaning of the 1940 Act.


                                       16
<PAGE>



REMUNERATION OF DIRECTORS AND OFFICERS 
   

     Effective June 28, 1995, the Open-end Fund Complex will pay each of the
nine Directors who is not an "interested person" an annual aggregate fee of 
$55,000, plus out-of-pocket expenses.  The Open-end Fund Complex will pay 
each of the members of the Fund's Audit Committee, which consists of the 
Fund's Directors who are not "interested persons," an additional annual 
aggregate fee of $10,000 for serving on such a committee.  The allocation of 
such fees will be among the three funds in the Open-end Fund Complex in 
direct proportion to their respective average net assets.  For the fiscal 
year December 31, 1996, the Fund paid approximately $389,000 in Directors' 
fees and expenses.  Directors who are also officers or affiliated persons 
receive no remuneration for their services as Directors.  The Fund's officers 
and employees are paid by the Adviser or its agents.  As of April 7, 1997, to 
Fund management's knowledge, the Directors and officers of the Fund, as a 
group, owned more than 1% of the outstanding common stock of the following 
Portfolios of the Fund: 2.0% Asian Equity Portfolio - Class A shares; 2.2% 
Emerging Markets Portfolio - Class B shares; 2.6% Latin American Portfolio - 
Class A shares and 2.9% Technology Portfolio - Class A Shares.  The following 
table shows aggregate compensation paid to each of the Fund's Directors by 
the Fund and the Fund Complex, respectively, in the fiscal year ended 
December 31, 1996. 

    

                                       17
<PAGE>

   
<TABLE>
<CAPTION>
                               COMPENSATION TABLE

- -------------------------------------------------------------------------------------------
(1)                      (2)            (3)                 (4)            (5)
NAME OF                  AGGREGATE      PENSION OR          ESTIMATED      TOTAL
PERSON,                  COMPENSATION   RETIREMENT          ANNUAL         COMPENSATION
POSITION                 FROM           BENEFITS ACCRUED    BENEFITS       FROM REGISTRANT
                         REGISTRANT     AS PART OF FUND     UPON           AND FUND COMPLEX
                                        EXPENSES            RETIREMENT     PAID TO DIRECTORS
- --------------------------------------------------------------------------------------------

<S>                     <C>             <C>                 <C>            <C>
Barton M. Biggs,        $   N/A         N/A                 N/A            $    N/A
Director and Chairman
of the Board

Warren J. Olsen,            N/A         N/A                 N/A                 N/A
Director and President

John D. Barrett, II      59,485         N/A                 N/A              68,777
Director

Gerard E. Jones,         59,485         N/A                 N/A              75,877
Director


Andrew McNally, IV       55,023         N/A                 N/A              63,195
Director

Samuel T. Reeves         53,287         N/A                 N/A              61,331
Director

Fergus Reid              67,434         N/A                 N/A              77,220
Director

Frederick O. Robertshaw  50,834         N/A                 N/A              58,777
Director

Frederick B. Whittemore*    N/A         N/A                 N/A                 N/A
Director

</TABLE>

___________
* As of March 14, 1997, Mr. Whittemore resigned from the 
  Board of Directors.
    
                                       18
<PAGE>


INVESTMENT ADVISORY AND ADMINISTRATIVE AGREEMENTS
   
     Morgan Stanley Asset Management Inc. ("MSAM" or the "Adviser") is a 
wholly-owned subsidiary of Morgan Stanley Group Inc.  The principal offices 
of Morgan Stanley Group Inc. are located at 1221 Avenue of the Americas, New 
York, NY 10020.  As compensation for advisory services for the fiscal years 
ended December 31, 1994, December 31, 1995 and December 31, 1996, the Adviser 
earned fees of approximately $34,338,000, $40,534,000 and $55,465,000, 
respectively, and from such fees voluntarily waived fees of $2,640,000, 
$3,526,000 and $4,340,000, respectively.  For the fiscal years ended December
31, 1994, December 31, 1995 and December 31, 1996, the Fund paid brokerage 
commissions of approximately $7,287,293, $10,317,515 and $17,014,335, 
respectively.  For the fiscal years ended December 31, 1994, December 31, 
1995 and December 31, 1996, the Fund paid in the aggregate $796,000, $377,000 
and $826,686, respectively, as brokerage commissions to Morgan Stanley & 
Co. Incorporated, an affiliated broker-dealer, which represented 11%, 4% and 
4% of the total amount of brokerage commissions paid in each respective 
period.  For the fiscal years ended December 31, 1994, December 31, 1995 and 
December 31, 1996, the Fund paid administrative fees to MSAM of approximately 
$4,458,000, $5,238,000 and $7,298,531, respectively.
    
     Pursuant to the MSAM Administration Agreement between the Adviser and the
Fund, the Adviser provides Administrative Services.  For its services under the
Administration Agreement, the Fund pays the Adviser a monthly fee which on an
annual basis equals 0.15 of 1% of the average daily net assets of the Portfolio.
   
     Under the Agreement between the Adviser and The Chase Manhattan Bank
("Chase"), Chase Global Funds Services Company ("CGFSC", a corporate affiliate
of Chase) provides certain administrative services to the Fund.  CGFSC provides
operational and administrative services to investment companies with
approximately $69 billion in assets and having approximately 215,930 shareholder
accounts as of December 31, 1996.  CGFSC's business address is 73 Tremont
Street, Boston, Massachusetts 02108-3913.
    
DISTRIBUTION OF FUND SHARES

     Morgan Stanley & Co. Incorporated (the "Distributor"), a wholly-owned
subsidiary of Morgan Stanley Group Inc., serves as the Distributor of the Fund's
shares pursuant to a Distribution Agreement for the Fund and a Plan of
Distribution for the Class B shares of the Portfolio pursuant to Rule 12b-1
under the 1940 Act (the "Plan").  Under the Plan the Distributor is entitled to
receive from the Portfolio a distribution fee, which is accrued daily and paid
quarterly, at an annual rate of up to 0.25% of the average daily net assets of
the Class B shares of the Portfolio.  The Distributor expects to allocate most
of its fee to its investment representatives and investment dealers, banks or
financial service firms that provide distribution services ("Participating
Dealer").  The actual amount of such compensation is agreed upon by the Fund's
Board of Directors and by the Distributor.  The Distributor may, in its
discretion, voluntarily waive from time to time all or any portion of its
distribution fee and the Distributor is free to make additional payments out of
its own assets to promote the sale of Fund shares.

   
     The Plan obligates the Portfolio to accrue and pay to the Distributor the
fee agreed to under its Distribution Agreement. The Plan does not obligate the
Portfolio to reimburse the Distributor for the actual expenses the Distributor
may incur in fulfilling its obligations under the Plan.  Thus, under the Plan,
even if the Distributor's actual expenses exceed the fee payable to it
thereunder at any given time, the Portfolio will not be obligated to pay more
than that fee.  If the Distributor's actual expenses are less than the fee it
receives, the Distributor will retain the full amount of the fee.  The Plan for
the Class B shares were most recently approved by the Fund's Board of Directors,
including those directors who are not "interested persons" of the Fund as that
term is defined in the 1940 Act and who have no direct or indirect financial
interest in the operation of a Plan or in any agreements related thereto, on
February 13, 1997.
    

CODE OF ETHICS

     The Board of Directors of the Fund has adopted a Code of Ethics under Rule
17j-1 of the 1940 Act which incorporates the Code of Ethics of the Adviser
(together, the "Codes").  The Codes significantly restrict the personal
investing activities of all employees of the Adviser and, as described below,
impose additional, more onerous, restrictions on the Fund's investment
personnel.

     The Codes require that all employees of the Adviser preclear any personal
securities investment (with limited exceptions, such as government securities).
The preclearance requirement and associated procedures are designed to identify
any substantive prohibition or limitation applicable to the proposed investment.
The substantive restrictions applicable to all employees of the Adviser include
a ban on acquiring any securities in a "hot" initial public offering and a
prohibition from profiting on short-term trading in


                                       19
<PAGE>


securities.  In addition, no employee may purchase or sell any security that at
the time is being purchased or sold (as the case may be), or to the knowledge of
the employee is being considered for purchase or sale, by any fund advised by
the Adviser.  Furthermore, the Codes provide for trading "blackout periods" that
prohibit trading by investment personnel of the Fund within periods of trading
by the Fund in the same (or equivalent) security.

   

CONTROL PERSONS AND PRINCIPAL HOLDERS OF SECURITIES

     The names and addresses of the holders of 5% or more of the outstanding
shares of any class of the Fund as of April 7, 1997 and the percentage of
outstanding shares of such classes owned beneficially or of record by such
shareholders as of such date are, to Fund management's knowledge, as follows:

ACTIVE COUNTRY ALLOCATION PORTFOLIO:  City of New York Deferred Compensation 
Plan, 40 Rector Street, 3rd Floor, New York, NY 10006, owned 26% of such 
Portfolio's total outstanding Class A shares.

The Trustees of Columbia University in the City of New York, 475 Riverside 
Drive, Suite 401, New York, NY 10115, owned 15% of such Portfolio's total 
outstanding Class A shares.

Oglebay Norton Company, 1100 Superior Avenue, Cleveland, OH 44114-2598, owned
11% of such Portfolio's total outstanding Class A shares.

Boatmen's Trust Co., Pension Plan, P.O. Box 14737, St. Louis, MO 63178-4737 
owned 7% of such Portfolio's total outstanding Class A shares.

The Flinn Foundation, Northern Trust Co., Master Trust Dept., 7th Floor, 
P.O. Box 92984, Chicago, IL 60675, owned 6% of such Portfolio's total 
outstanding Class A shares.

Sahara Enterprises, Inc., 3 First National Plaza, Suite 2000, Chicago, IL 60602-
4260, owned 7% of such Portfolio's total outstanding Class A shares.

The Chase Manhattan Bank, N.A., Trustee Chubb Capital Accumulation Plan, 770
Broadway, New York, NY 10003, owned 7% of such Portfolio's total outstanding
Class A shares.

Fredric W. & Stephanie C. Harman, 21 Hillbrook, Portola Valley, CA 94028, 
owned 54% of such Portfolio's total outstanding Class B shares.

David M. & Sharon M. Platter, 9 Palmer Lane, Riverside, CT 06878, owned 46% of
such Portfolio's total outstanding Class B shares.

AGGRESSIVE EQUITY PORTFOLIO:  Ministers and Missionaries Benefit Board of the 
American Baptist Churches, Attn: Morgan Stanley Asset Management, 1221 Avenue 
of the Americas, New York, NY 10020, owned 11% of such Portfolio's total 
outstanding Class A shares.

Northern Trust Company Trustee, FBO Morgan Stanley Profit Sharing Plan, P.O.
Box 92956, Chicago, IL 60675-2956, owned 9% of such Portfolio's total 
outstanding Class A shares.

Valassis Enterprises - Equity C/O Franklin Enterprises, 520 Lake Cook Road, 
Suite 380, Deerfield, IL 60015, owned 6% of such Portfolio's total 
outstanding Class A shares.

Kinghugh S.A., C/O Morgan Stanley Asset Management, 1221 Avenue of the Americas,
New York, NY 10020, owned 6% of such Portfolio's total outstanding Class A
shares.

Bank Morgan Stanley AG, Bahnogstrasse 92, Zurich CH-8023, Switzerland owned 
6% of such Portfolio's total outstanding Class A shares.


                                       20
<PAGE>

ASIAN EQUITY PORTFOLIO:  Association De Biensfaissance Et De Retraite Des
Pollciers De La Communaute Urbaine De Montreal, 480 Gilford Street, Montreal,
Quebec H2J1N3, owned 9% of such Portfolio's total outstanding Class A shares.

Northern Trust Company Trustee, FBO Morgan Stanley Profit Sharing Plan, P.O. 
Box 92956, Chicago, IL 60675-2956, owned 6% of such Portfolio's total 
outstanding Class A shares.

James L. & Sarah M. Barksdale, Trustees of Jim & Sally Barksdale, 800 
Woodlands Parkway, Suite 118, Ridgeland, MS 39157-5216 owned 6% of such 
Portfolio's total outstanding Class B shares.

BALANCED PORTFOLIO:  Kinney Printing Co-Employees, 4801 So. Lawndale, Chicago, 
IL 60632-3018, owned 16% of such Portfolio's total outstanding Class A shares.

H. Conrad & Sarah Meyer, One Woodland Avenue, Bronxville, NY 10708, owned 12%
of such Portfolio's total outstanding Class A shares.

Joan M. Hunt Trust, 8627 Madison Drive, Niles, IL 60648, owned 8% of such 
Portfolio's total outstanding Class A shares.

Guarantee & Trust Company, IRA Rollover, One Woodland Avenue, Bronxville, NY
10708, owned 7% of such Portfolio's total outstanding Class A shares.

William Guthrie, IRA Rollover, 435 Sheridan Road, Winnetka, IL  60093-2626,
owned 32% of such Portfolio's total outstanding Class B shares.

Ramakrishna Kothalanka M.D., Profit Sharing Plan, MSTC Custodian, 126 Bentley
Avenue, Jersey City, NJ 07304-1702, owned 16% of such Portfolio's total
outstanding Class B shares.

Sam G. Pitroda Custodian for Rajal Pitroda, 1480 Goldenbell Court, Downers 
Grove, IL 60515-1301, owned 8% of such Portfolio's total outstanding Class B 
shares.

Sam G. Pitroda Custodian for Salil Pitroda, 1480 Goldenbell Court, Downers 
Grove, IL 60515-1301, owned 8% of such Portfolio's total outstanding Class B 
shares.

Phyllis M. Mott IRA, MSTC Custodian, 120 West State Street, Suite 400, 
Rockford, IL 61101, owned 8% of such Portfolio's total outstanding 
Class B shares.

EMERGING GROWTH PORTFOLIO:  Northern Trust Company Trustee, FBO Morgan Stanley
Profit Sharing Plan, P.O. Box 92956, Chicago, IL 60675-2956, owned 47% of such
Portfolio's total outstanding Class A shares.

Allendale Mutual Insurance Co., P.O. Box 7500, Johnston, RI 02919-0750, owned
17% of such Portfolio's total outstanding Class A shares.

NOAM/A/EC, C/O Philip Winters, Morgan Stanley Asset Management, 1221 6th Avenue,
New York, NY 10020, owned 8% of such Portfolio's total outstanding Class A 
shares.

South Trust Estate & Trust Company of Georgia, Trustee U/A Southern Engineering
Company Retirement Plan, P.O. Box 1001, Atlanta, GA 30301, owned 7% of such 
Portfolio's total outstanding Class A shares.

HVA Limited Partnership, C/O H L Van Arnem, 1301 W. Newport Center Drive, 
Deerfield Beach, FL 33442-7734, owned 11% of such Portfolio's total outstanding 
Class B shares.

Anne W. Rohrbach, C/O Gleacher Avenue, 660 Madison Avenue, 19th Floor, New 
York, NY 10021, owned 11% of such Portfolio's total outstanding Class B 
shares.

Lawrence M. Howell, Howell Capital, One Maritime Plaza, Suite 1700, 
San Francisco, CA 94101, owned 7% of such Portfolio's total outstanding
Class B shares.

Julian Eisner, 871 Oak Lane, North Woodmere, NY 11581, owned 7% of such 
Portfolio's total outstanding Class B shares.

H. Conrad & Sarah Meyer, One Woodland Avenue, Bronxville, NY 10708, owned 6% of
such Portfolio's total outstanding Class B shares.

Bruce S. Ives, 163 Gallows Hill Road, West Redding, CT 06896, owned 6% of 
such Portfolio's total outstanding Class B shares.

William B. O'Connor, 18 Montfort Road, Port Washington, NY 11050, owned 6% of 
such Portfolio's total outstanding Class B shares.

James F. & Marlene Connors, 205 E. Joppa Road, Towson, MD 21286, owned 5% of 
such Portfolio's total outstanding Class B shares.

EMERGING MARKETS DEBT PORTFOLIO:  Northwestern University, 633 Clark Street,
Evanston, IL 60208-1122, owned 20% of such Portfolio's total outstanding Class A
shares.

Valassis Enterprises - Equity, C/O Franklin Enterprises, 520 Lake Cook Road, 
Deerfield, IL 60015, owned 6% of such Portfolio's total outstanding Class A
shares.

Northern Trust Company Trustee, FBO Morgan Stanley Profit Sharing Plan, P.O. Box
92956, Chicago, IL 60675-2956, owned 6% of such Portfolio's total outstanding 
Class A shares.

Swarthmore College, 500 College Avenue, Swarthmore, PA 19081-1110, owned 7% of
such Portfolio's total outstanding Class A shares.

Morgan Stanley & Co. Pension Fund, C/O Northern Trust Co., 770 Broadway, New 
York, NY 10003, owned 7% of such Portfolio's total outstanding Class A shares.

Michael J. Fuchs, 9 West 57th Street, New York, NY 10019, owned 11% of such 
Portfolio's total outstanding Class B shares.

Alice H. & Paul D. Bartlett, 4800 Main Street, Kansas City, MO 64112, owned 
11% of such Portfolio's total outstanding Class B shares.

Daniel E. Winters, 1319 Mirror Terrace NW, Winter Haven, FL 33881, owned 8% of 
such Portfolio's total outstanding Class B shares.

Bruce A. Drummond, 1847 Onaway SE, Grand Rapids, MI 49506, owned 6% of such 
Portfolio's total outstanding Class B shares.

Eleanor S. Herkert Trustee of the Eleanor S. Herkert Trust, 2000 Diana Drive,
Lakeview West, Hallandale, FL 33009, owned 6% of such Portfolio's total 
outstanding Class B shares.

David Brooks Gendron, 2 Montpelier Place, London SW7 1HJ England, UK, owned 
6% of such Portfolio's total outstanding Class B shares.

Paul D. Bartlett, Jr., 4800 Main Street, Suite 600, Kansas City, MO 64112, 
owned 5% of such Portfolio's total outstanding Class B shares.

EMERGING MARKETS PORTFOLIO:  Ministers & Missionaries Benefit Board of the
American Baptist Churches, 475 Riverside Drive, New York, NY 10115, owned 7% of
such Portfolio's total outstanding Class A shares.

Ewing Marion Kauffman Foundation, 4900 Oak Street, Kansas City, MO 64112, owned
7% of such Portfolio's total outstanding Class A shares.

EQUITY GROWTH PORTFOLIO:  Fidelity Management Trust Company as Trustee for 
GTE Master Savings Trust, 82 Devonshire Street, Boston, MA 02109, owned 25% 
of such Portfolio's total outstanding Class A shares.

Northern Trust Company Trustee, FBO Morgan Stanley Profit Sharing Plan, P.O. 
Box 92956, Chicago, IL 60675, owned 17% of such Portfolio's total outstanding 
Class A shares.

St. Raymonds Cemetery Reserve Fund, P.O. Box 92800, Rochester, NY 14692, owned
5% of such Portfolio's total outstanding Class A shares.

Fidelity Investments Institutional Operations Company, Agent for Certain 
Employee Benefit Plans, 100 Magellan Way, Covington, KY 41015, owned 8% of such 
Portfolio's total outstanding Class A shares.

Philip E. Asquith, 31 Lakeside Drive, Ramsey, NJ 07446, owned 5% of such
Portfolio's total outstanding Class B shares.


                                       21
<PAGE>

EUROPEAN EQUITY PORTFOLIO:  Marc Andreessen Trustees, FBO Marc Andreessen, 
16615 Lark Avenue, Los Gatos, CA 95030, owned 12% of such Portfolio's total 
outstanding Class B shares.

Wayne Gretzky Trustee of the Gretzky Trust of 1989, 9100 Wilshire Boulevard,
Beverly Hills, CA 90210, owned 6% of such Portfolio's total outstanding 
Class B shares.

Paul M. and Shirley F. Mathews, 25 West 706 Jerome Avenue, Wheaton, IL 60187,
owned 6% of such Portfolio's total outstanding Class B shares.

William & Brenda Castonguay, 9101 Hometown Drive, Raleigh, NC 27615, owned 5% 
of such Portfolio's total outstanding Class B shares.

FIXED INCOME PORTFOLIO:  Northern Trust Company Trustee, FBO Morgan Stanley
Profit Sharing Plan, P.O. Box 92956, Chicago, IL 60675-2956, owned 29% of such
Portfolio's total outstanding Class A shares.

Brooks School, C/O Mr. Frank Marino, North Andover, MA 01845, owned 7% of such
Portfolio's total outstanding Class A shares.

Trust for Descendents of David R. Jaffe, C/O David Jaffe, 45 Hemlock Ridge, 
Weston, CT 06883, owned 8% of such Portfolio's total outstanding Class B 
shares.

Laverne M. Brownsey Trust UA, 135 S. LaSalle Street, Chicago, IL 60603, owned
7% of such Portfolio's total outstanding Class B shares.

First United Methodist Church of Chicago - Endowment Fund, 77 West Washington,
Chicago, IL 60602, owned 7% of such Portfolio's total outstanding Class
B shares.

Cascino Investment Co.,820 Burgess Hill, Naperville, IL 60565, owned 16% of 
such Portfolio's total outstanding Class B shares.

Marvin J. Schneider, MSTC Custodian, 12331 Ladue Road, St. Louis, MO 63141, 
owned 8% of such Portfolio's total outstanding Class B shares.

Joan M. Hunt, MSTC Custodian, 8627 Madison Drive, Niles, IL 60648, owned 7% 
of such Portfolio's total outstanding Class B shares.

Michael S. Virgil, FBO Mary Ann Young Brownsey Trust, 135 S. LaSalle Street, 
Chicago, IL 60603, owned 7% of such Portfolio's total outstanding Class B 
shares.

Joan O. Benjamin, 10 Saint Lukes Place, New York, NY 10014, owned 7% of such 
Portfolio's total outstanding Class B shares.

John K. Howe, MSTC Custodian, 7274 East Las Palmaritas Drive, Scottsdale, AZ 
85258, owned 7% of such Portfolio's total outstanding Class B shares.

GLOBAL EQUITY PORTFOLIO:  Robert College of Istanbul Turkey C/O Morgan Stanley
Asset Management, 25 Cabot Square, London, England E144QA, owned 47% of such
Portfolio's total outstanding Class A shares.

JM Kaplan Fund, Inc., 880 Third Avenue, 3rd floor, New York, NY 10022, owned 
13% of such Portfolio's total outstanding Class A shares.


                                       22
<PAGE>

Kaplan, Choate Value Partners, L.P., 880 Third Avenue, New York, NY 10022-4730,
owned 9% of such Portfolio's total outstanding Class A shares.

Gooss & Company, C/O Chase Manhattan Bank, 1211 6th Avenue, New York, NY 10036,
owned 7% of such Portfolio's total outstanding Class A shares.

Divtex and Company FBO, Pritchard Hubble and Herr C/O Texas Commerce Bank, P.O.
Box 2558, Houston, TX 77252, owned 7% of such Portfolio's total outstanding
Class A shares.

Bank of Mississippi, P.O. Box 1605, Jackson, MS 39215, owned 13% of such 
Portfolio's total outstanding Class B shares.

Fidelity Investments Institutional Operations as Agent for Certain Employee 
Benefit Plans, 100 Magellan Way, Covington, KY 41015, owned 13% of such 
Portfolio's total outstanding Class B shares.

Edward J. Prostic, 2225 Stratford Road, Mission Hills, KS 66208, owned 9% of 
such Portfolio's total outstanding Class B shares.

V. Marc Droppert IRA, MSTC Custodian, 13106 184th NE, Redmond, WA 98052, owned 
8% of such Portfolio's total outstanding Class B shares.

North American Trust Company, FBO Heller/Robert S. Venning, P.O. Box 84419, San
Diego, CA  92138, owned 7% of such Portfolio's total outstanding Class B
shares.

Leslie E. Tiffany IRA, MSTC, 14312 173rd Place NE, Redmond, WA 98052, owned 6% 
of such Portfolio's total outstanding Class B shares.

GLOBAL FIXED INCOME PORTFOLIO:  Farm Credit Bank Retirement Plan, Columbia
District American Industries Trust Company Trustee, 5700 NW Central Drive, 4th
Floor, Houston, TX 77092, owned 19% of such Portfolio's total outstanding Class
A shares.

Northern Trust Company as Custodian FBO The Lund Foundation, P.O. Box 92956,
Chicago, IL 60675, owned 15% of such Portfolio's total outstanding Class A
shares.

The Northern Trust Co. FBO Christel Dehaan Trust, P.O. Box
92956, Chicago, IL 60675-2956, owned 6% of such Portfolio's total outstanding
Class A shares.

Lakeview Holdings Ltd., Coutts & Co. (Bahamas) Ltd., P.O. Box N7788, West Bay 
St., Nassau Bahamas, owned 5% of such Portfolio's total outstanding Class A 
shares. 

David Brooks Gendron, 2 Montpelier Place, London SW7 1HJ, England, UK, owned 34%
of such Portfolio's total outstanding Class B shares.

Joan M. Hunt, MSTC Custodian, 8627 Madison Drive, Niles, IL 60648, owned 17% 
of such Portfolio's total outstanding Class B shares.

Laverne M. Brownsey Trust UA, 135 S. LaSalle Street, Chicago, IL 60603, owned 
16% of such Portfolio's total outstanding Class B shares.

George & Claudine Boutros, 11007 Branbrook, Houston, TX 77042, owned 7% of
such Portfolio's total outstanding Class B shares.

George N. and Susan P. Fugelsang, 17 Calhoun Drive, Greenwich, CT 06831, owned 
10% of such Portfolio's total outstanding Class B shares.

Paul E. & H. Anthony Hellmers, 4 Colonial Lane, Larchmont, NY 10538, owned 7% 
of such Portfolio's total outstanding Class B shares.

Anthony F. & Colette H. Rowland, C/O Cambrian Management, 1114 Avenue of the 
Americas, New York, NY 10036, owned 6% of such Portfolio's total outstanding 
Class B shares.

GOLD PORTFOLIO:  William H. Ellis Trustee, Living Trust, Attn: Julie J. Laux,
2519 N. Bosworth, Chicago, IL 60614, owned 6% of such Portfolio's total 
outstanding Class A shares.

                                       23
<PAGE>

Marshall & Ilsley Trust Company, C/F John Morey, 1000 N. Water Street, 
Milwaukee, WI 53202, owned 26% of such Portfolio's total outstanding 
Class B shares.

Barlett and Company, Profit Sharing Plan and Trust, 4800 Main Street, Kansas
City, MO 64112, owned 20% of such Portfolio's total outstanding Class B shares.

Chicago Methodist Episcopal Church Aid Society, C/O Gordon Worley, 4401 Gulf
Shore Boulevard North, Monaco Beach Club, Naples, FL 33940, owned 18% of such 
Portfolio's total outstanding Class B shares.

Steven C. Olson, 505 Knollwood Road, Ridgewood, NJ 07450, owned 16% of such
Portfolio's total outstanding Class B shares.

Priscilla & John Privat, Community Property, 8852 N.E. 24th Street, Bellevue,
WA 98004, owned 6% of such Portfolio's total outstanding Class B shares.

HIGH YIELD PORTFOLIO:  Northern Trust Company Trustee, FBO Morgan Stanley Profit
Sharing Plan, P.O. Box 92956, Chicago, IL 60675-2956, owned 21% of such
Portfolio's total outstanding Class A shares.

Valassis Enterprises - Equity, c/o Franklin Enterprises, 520 Lake Cook Road,
Suite 380, Deerfield, IL 60015, owned 12% of such Portfolio's total outstanding
Class A shares.

Adeliade L. Hinckley, C/O Jim Bell, Morgan Stanley/IIS Department, 1251 Avenue 
of the Americas, New York, NY 10020, owned 7% of such Portfolio's total 
outstanding Class B shares.


INTERNATIONAL EQUITY PORTFOLID: Ramakrishna Kothalanka M.D., IRA Rollover, MSTC
Custodian, 126 Bentley Avenue, Jersey City, NJ 07304, owned 5% of such 
Portfolio's total outstanding Class B shares.

Fleet Bank, Trustee for Third Presbyterian Church, P.O. Box 92800, Rochester, NY
14692, owned 17% of such Portfolio's total outstanding Class B shares.

INTERNATIONAL MAGNUM PORTFOLIO:  Bankers Trust Trustee, Harris Corporation 
Retirement Plan & Harris Corporation Union Retirement Plan, 1025 W. Nasa 
Boulevard, Melbourne, FL 32919, owned 47% of such Portfolio's total outstanding
Class A shares.


                                       24
<PAGE>

Southwest Guaranty Trust Co., 2121 Sage Road, Suite 150, Houston TX 77056, 
owned 6% of such Portfolio's total outstanding Class A shares.

Fidelity Investments Institutional Operations Company, Agent for Certain 
Employee Benefit Plans, 100 Magellan Way, Covington, KY 41015, owned 83% 
of such Portfolio's total outstanding Class B shares.

INTERNATIONAL SMALL CAP PORTFOLIO:  The Short Brothers Pension Fund, P.O. Box
241, Airport Road, Belfast, N. Ireland, owned 11% of such Portfolio's total
outstanding Class A shares.

Trustees of Boston College Attn:  Paul Haran Associate Treasurer, St. Thomas
More Hall 310, Chestnut Hill, MA 02167, owned 7% of such Portfolio's total
outstanding Class A shares.

General Mills, Inc. Master Trust:  Pooled International Fund, One General Mills
Blvd., Minneapolis, MN 55426, owned 7% of such Portfolio's total outstanding
Class A shares.

JAPANESE EQUITY PORTFOLIO:  United Carolina Bank Trust Operations, 
P.O. Box 632, Whiteville, NC 28472, owned 23% of such Portfolio's
total outstanding Class B shares.

Barlett and Company, Profit Sharing Plan and Trust,
4800 Main Street, Kansas City, MO 64112, owned 14% of such Portfolio's total
outstanding Class B shares.

Paul M. & Shirley F. Mathews, 25 W. 706 Jerome Avenue, Wheaton, IL 60187, 
owned 7% of such Portfolio's total outstanding Class B shares.

William & Brenda Castonguay, 9101 Hometown Drive, Raleigh, NC 27615, owned 
7% of such Portfolio's total outstanding Class B shares.

Wayne Gretzky Trustee of the Gretzky Trust of 1989, 9100 Wilshire Boulevard,
Beverly Hills, CA 90210, owned 6% of such Portfolio's total outstanding 
Class B shares.

Douglas E. Ebert, Trustee and Successor in Trust, 326 Vailwood Court, 
Bloomfield Hills, MI 48302, owned 6% of such Portfolio's total outstanding 
Class B shares.

LATIN AMERICAN PORTFOLIO:  Investors Bank & Trust Co., Financial Product 
Services, P.O. Box 1537, Boston, MA 02205, owned 10% of such Portfolio's total 
outstanding Class A shares.

MUNICIPAL BOND PORTFOLIO:  Daniel F. and Maria J. McDonald, 8550 Old
Dominion Drive, McLean, VA 22102, owned 11% of such Portfolio's total
outstanding Class A shares.

Donna Karan, C/O Stephan Weiss, The Donna Karan Company, 550 Seventh Avenue,
New York, NY 10018, owned 6% of such Portfolio's total outstanding 
Class A shares.

Frank R. Mori, 935 Park Avenue, New York, NY 10028, owned 8% of such 
Portfolio's total outstanding Class A shares.

Cushman Trust, C/O Cambrian Services, 1114 Avenue of the Americas, Suite 2702,
New York, NY  10036, owned 6% of such Portfolio's total outstanding Class A
shares.

Arnold E. and Jill I. Bellowe Trustees, 915 Park Lane, Montecito, CA  93108-
1421, owned 6% of such Portfolio's total outstanding Class A shares.

Sevenson Environmental Services, P.O. Box 396, 2749 Lockport Road, Niagra Falls,
NY 14305, owned 6% of such Portfolio's total outstanding Class A shares.


                                       25
<PAGE>

SMALL CAP VALUE EQUITY PORTFOLIO:  Valassis Enterprises - Equity, C/O Franklin 
Enterprises, 520 Lake Cook Road, Deerfield, IL 60015, owned 8% of such
Portfolio's total outstanding Class A shares.

McMahan Furniture Company, Attn: Richard A. McMahan, P.O. Box 8000, Carlsbad, CA
92018, owned 7% of such Portfolio's total outstanding Class A shares.

William H. Ellis Trustee, William Ellis Living Trust, 2519 N. Bosworth, 
Chicago, IL 60614, owned 5% of such Portfolio's total outstanding 
Class A shares.

Barlett and Company, Profit Sharing Plan and Trust, 4800 Main Street, Kansas 
City, MO 64112, owned 31% of such Portfolio's total outstanding Class B 
shares.

David Brooks Gendron, 2 Montpelier Place, London SW7 1HJ England, UK, 
owned 14% of such Portfolio's total outstanding Class B shares.

Robert R. Bennett IRA Rollover, MSTC Custodian, 18853 N. 88th Drive, Peoria, 
AZ 85382, owned 10% of such Portfolio's total outstanding Class B shares.

Ramakrishna Kothalanka M.D., IRA Rollover, MSTC Custodian, 126 Bentley Avenue,
Jersey City, NJ 07304, owned 9% of such Portfolio's total outstanding 
Class B shares.

Kinney Printing Co-Employees, Attn:  Dolores M. Miklos, 4801 South Lawndale,
Chicago, IL 60632-3018, owned 9% of such Portfolio's total outstanding Class B
shares.

Frank E. Hunt Trust, 8627 Madison Drive, Niles, IL 60648, owned 5% of such 
Portfolio's total outstanding Class B shares.

TECHNOLOGY PORTFOLIO: Goolock Associates, C/O Oppenheimer & Co. Inc., 200 
Liberty Street, New York, NY 10281, owned 21% of such Portfolio's total 
outstanding Class A shares.

Misty Investment Limited, N7776, Nassau, Bahamas, owned 10% of such 
Portfolio's total outstanding Class A shares.

Peter Karmanos Jr., 4740 Dow Ridge, Orchard Lake, MI 48324, owned 10% of 
such Portfolio's total outstanding Class A shares.

Robert F. Bernard, C/O Whittman-Hart, 311 S. Wacker Drive, Chicago, IL 60606,
owned 8% of such Portfolio's total outstanding Class A shares.

John Montelione, 619 Tremont Street, Sarasota, FL 34242, owned 6% of such 
Portfolio's total outstanding Class A shares.

Trefoil Inc., 179 St. Paul Avenue, Brantford Ontario, Canada N3T4G5, 
owned 5% of such Portfolio's total outstanding Class A shares.

William J. Connolly, 63 Blackhawk Club Court, Danville, CA 94506, owned 5% 
of such Portfolio's total outstanding Class A shares.

Brian E. Bellows, 6133 Pasadena Point Boulevard, Gulfport, FL 33707,
owned 18% of such Portfolio's total outstanding Class B shares.

Robert J. Weinstein M.D., & Lois Weinstein, 875 N. Michigan Avenue, Chicago, IL
60611, owned 8% of such Portfolio's total outstanding Class B shares.

Paul Krieger, 23 Fairview Avenue, Great Neck, NY 11023, owned 7% of such 
Portfolio's total outstanding Class B shares.

U.S. REAL ESTATE PORTFOLIO:  European Patent Organization Pension Reserve Fund,
Erhardt Strasse 27, Munich, 80331 Germany, owned 7% of such Portfolio's total
outstanding Class A shares.

Morgan Stanley & Co. Pension Fund, C/O Northern Trust Company Cust, 770
Broadway, New York, NY  10003, owned 8% of such Portfolio's total outstanding
Class A shares.

Northwestern University, Attn: Investment Department, 633 Clark Street, 
Evanston, IL 60208, owned 10% of such Portfolio's total outstanding Class A 
shares.

Northern Trust Company Trustee, FBO Morgan Stanley Profit Sharing Plan, P.O.
Box 92956, Chicago, IL 60675, owned 6% of such Portfolio's total outstanding 
Class A shares.

Charles Schwab & Co. Inc., 101 Montgomery Street, San Francisco, CA 94104, 
owned 5% of such Portfolio's total outstanding Class A shares.

Kansas Children's Service League, P.O. Box 517, Wichita, KS 67201, owned 5% 
of such Portfolio's total outstanding Class B shares.

VALUE EQUITY PORTFOLIO:  McMahan Furniture Company, Attn: Richard A. McMahan,
P.O. Box 8000, Carlsbad, CA 92018, owned 8% of such Portfolio's total 
outstanding Class A shares.

Alice H. & Paul D. Bartlett, Trustees, 4800 Main Street, Kansas City, MO 64112,
owned 19% of such Portfolio's total outstanding Class B shares.

Paul D. Bartlett Jr., 4800 Main Street, Kansas City, MO 64112, owned 13% of 
such Portfolio's total outstanding Class B shares.

Cascino Investment Co., 820 Burgess Hill, Naperville, IL 60565, owned 11% of 
such Portfolio's total outstanding Class B shares.

David Brooks Gendron, 2 Montpelier Place, London SW7 1HJ England, UK, owned 
8% of such Portfolio's total outstanding Class B shares.

Delaware Charter Guarantee & Trust Company, C/F Nelaura O. Lewis, IRA Rollover,
78 Cedar Cliff Road, Riverside, CT 06878, owned 6% of such Portfolio's total 
outstanding Class B shares.

First United Methodist Church of Chicago - Endowment Fund, 77 West Washington,
Chicago, IL 60602, owned 6% of such Portfolio's total outstanding Class B 
shares.

George N. and Susan P. Fugelsang, 17 Calhoun Drive, Greenwich, CT 06831,
owned 6% of such Portfolio's total outstanding Class B shares.

Laverne M. Brownsey Trust, 135 S. LaSalle St., Chicago, IL 60603 owned 5% of 
such Portfolio's total outstanding Class B shares.

    

                             PERFORMANCE INFORMATION

     The Fund may from time to time quote various performance figures to
illustrate the Portfolio's past performance.

     Performance quotations by investment companies are subject to rules adopted
by the Commission, which require the use of standardized performance quotations.
In the case of total return, non-standardized performance quotations may be
furnished by the Fund but must be accompanied by certain standardized
performance information computed as required by the Commission. Current yield
and average annual compounded total return quotations used by the Fund are based
on the standardized methods of computing performance mandated by the Commission.
An explanation of those and other methods used by the Fund to compute or express
performance follows.


TOTAL RETURN


                                       26
<PAGE>


     From time to time the Portfolio may advertise total return.  Total return
figures are based on historical earnings and are not intended to indicate future
performance.  The average annual total return is determined by finding the
average annual compounded rates of return over 1-, 5-, and 10-year periods (or
over the life of the Portfolio) that would equate an initial hypothetical $1,000
investment to its ending redeemable value.  The calculation assumes that all
dividends and distributions are reinvested when paid.  The quotation assumes the
amount was completely redeemed at the end of each 1-, 5-, and 10-year period (or
over the life of the Portfolio) and the deduction of all applicable Fund
expenses on an annual basis.

   
     The cumulative (unannualized) total return since inception (September 
16, 1996) of the Portfolio is 7.10% for Class A and Class B shares.
    

     Total return figures are calculated according to the following formula:
P(1 + T) to the power of n = ERV

where:

P    =    a hypothetical initial payment of $1,000

T    =    average annual total return

n    =    number of years

ERV  =    ending redeemable value of hypothetical $1,000 payment made at the
          beginning of the 1-, 5-, or 10-year periods at the end of the 1-, 5-,
          or 10-year periods (or fractional portion thereof).



COMPARISONS

     To help investors better evaluate how an investment in the Portfolio might
satisfy their investment objective, advertisements regarding the Fund may
discuss various measures of Fund performance as reported by various financial
publications.  Advertisements may also compare performance (as calculated above)
to performance as reported by other investments, indices and averages.  The
following publications may be used:

       (a)     CDA Mutual Fund Report, published by CDA Investment
               Technologies, Inc. -- analyzes price, current yield, risk, total
               return and average rate of return (average annual compounded
               growth rate) over specified time periods for the mutual fund
               industry.

       (b)     Financial publications:  Business Week, Changing Times, Financial
               World, Forbes, Fortune, Money, Barron's, Consumer's Digest,
               Financial Times, Global Investor, Investor's Daily, Lipper
               Analytical Services, Inc., Morningstar, Inc., New York Times,
               Personal Investor, Wall Street Journal and Weisenberger
               Investment Companies Service -- publications that rate fund
               performance over specified time periods.

       (c)     Historical data supplied by the research departments of First
               Boston Corporation, the J.P. Morgan companies, Salomon Brothers,
               Merrill Lynch, Pierce, Fenner & Smith, Lehman Brothers and
               Bloomberg L.P.

       (d)     Lipper -- Mutual Fund Performance Analysis and Lipper -- Fixed
               Income Fund Performance Analysis -- measures total return and
               average current yield for the mutual fund industry.  Ranks
               individual mutual fund performance over specified time periods,
               assuming reinvestment of all distributions, exclusive of any
               applicable sales charges.

       (e)     Mutual Fund Source Book, published by Morningstar, Inc. --
               analyzes price, yield, risk and total return for equity funds.


       (f)     Savings and Loan Historical Interest Rates -- as published in the
               U.S. Savings & Loan League Fact Book.

       (g)     Stocks, Bonds, Bills and Inflation, published by Hobson
               Associates -- historical measure of yield, price and total return
               for common and small company stock, long-term government bonds,
               U.S. Treasury bills and inflation.

The following indices and averages may also be used:


                                       27
<PAGE>


       (a)     Composite Indices -- 70% Standard & Poor's 500 Stock Index and
               30% NASDAQ Industrial Index; 35% Standard & Poor's 500 Stock
               Index and 65% Salomon Brothers High Grade Bond Index; and 65%
               Standard & Poor's 500 Stock Index and 35% Salomon Brothers High
               Grade Bond Index.

       (b)     Consumer Price Index (or Cost of Living Index), published by the
               U.S. Bureau of Labor Statistics -- a statistical measure of
               change, over time, in the price of goods and services in major
               expenditure groups.

       (c)     Dow Jones Composite Average or its component averages -- an
               unmanaged index composed of 30 blue-chip industrial corporation
               stocks (Dow Jones Industrial Average), 15 utilities company
               stocks and 20 transportation stocks.  Comparisons of performance
               assume reinvestment of dividends.

       (d)     EMBI+ -- Expanding on the EMBI, which includes only Bradys, the
               EMBI+ includes a broader group of Brady Bonds, loans, Eurobonds
               and the U.S. Dollar local markets instruments.  A more
               comprehensive benchmark than the EMBI, the EMBI+ covers 49
               instruments from 14 countries.  At $96 billion, its market cap is
               nearly 50% higher than the EMBI's.  The EMBI+ is not, however,
               intended to replace the EMBI but rather to complement it.  The
               EMBI continues to represent the most liquid, most easily traded
               segment of the market, including more of the assets that
               investors typically hold in their portfolios.  Both of these
               indices are published daily.

       (e)     IFC Global Total Return Composite Index -- an unmanaged index of
               common stocks and includes 18 developing countries in Latin
               America, East and South Asia, Europe, the Middle East and Africa
               (net of dividends reinvested).

   
       (e)     Indata Equity-Median Stock Index -- an unmanaged index which
               includes an average asset allocation of 7.4% cash and 92.6%
               equity based on $___ billion in assets among ___ portfolios for
               the year ended December 31, 1996.
    

       (f)     Lipper Capital Appreciation Index -- a composite of mutual funds
               managed for maximum capital gains.

       (g)     Morgan Stanley Capital International Combined Far East Free ex-
               Japan Index -- a market-capitalization weighted index comprising
               stocks in Hong Kong, Indonesia, Korea, Malaysia, Philippines,
               Singapore, Taiwan and Thailand.  Korea is included in the MSCI
               Combined Far East Free ex Japan Index at 20% of its market
               capitalization.

       (h)     Morgan Stanley Capital International EAFE Index -- an arithmetic,
               market value-weighted average of the performance of over 900
               securities on the stock exchanges of countries in Europe,
               Australia and the Far East.

       (i)     Morgan Stanley Capital International Emerging Markets Global
               Latin America Index -- an unmanaged, arithmetic market value
               weighted average of the performance of over 196 securities on the
               stock exchanges of Argentina, Brazil, Chile, Colombia, Mexico,
               Peru and Venezuela (assumes reinvestment of dividends).

       (j)     Morgan Stanley Capital International Europe Index -- an unmanaged
               index of common stocks and includes 14 countries throughout
               Europe.

       (k)     Morgan Stanley Capital International Japan Index -- an unmanaged
               index of common stocks.

       (l)     Morgan Stanley Capital International Latin America Index -- a
               broad-based market capitalization-weighted composite index
               covering at least 60% of markets in Mexico, Argentina, Brazil,
               Chile, Colombia, Peru and Venezuela (assumes dividends
               reinvested).

       (m)     Morgan Stanley Capital International World Index -- an
               arithmetic, market value-weighted average of the performance of
               over 1,470 securities listed on the stock exchanges of countries
               in Europe, Australia, the Far East, Canada and the United States.



       (n)     NASDAQ Composite Index -- an unmanaged index of common stocks.

       (o)     NASDAQ Industrial Index -- a capitalization-weighted index
               composed of more than 3,000 domestic stocks taken from the
               following industry sectors: agriculture, mining, construction,
               manufacturing, electronic components, services and public
               administration enterprises.  It is a value-weighted index
               calculated on price change only and does not include income.


                                       28
<PAGE>


       (p)     The New York Stock Exchange composite or component indices --
               unmanaged indices of all industrial, utilities, transportation
               and finance company stocks listed on the New York Stock Exchange.


       (q)     Russell 2500 Index -- comprised of the bottom 500 stocks in the
               Russell 1000 Index which represents the universe of stocks from
               which most active money managers typically select; and all the
               stocks in the Russell 2000 Index. The largest security in the
               index has a market capitalization of approximately 1.3 billion.

       (r)     Standard & Poor's 500 Stock Index or its component indices --
               unmanaged index composed of 400 industrial stocks, 40 financial
               stocks, 40 utilities company stocks and 20 transportation stocks.
               Comparisons of performance assume reinvestment of dividends.


       (s)     Standard & Poor's Small Cap 600 Index -- a capitalization-
               weighted index of 600 domestic stocks having market
               capitalizations which reside within the 50th and the 83rd
               percentiles of the market capitalization of the entire stock
               market, chosen for certain liquidity characteristics and for
               industry representation.

       (t)     Wilshire 5000 Equity Index or its component indices -- represents
               the return on the market value of all common equity securities
               for which daily pricing is available.  Comparisons of performance
               assume reinvestment of dividends.

       (u)     Lipper Science and Technology Fund Index -- a composite index of
               the mutual funds which invest at least 65% of their assets in
               science and technology stocks.

       (v)     Hambrecht and Quist Technology Index is an index of computer and
               chip makers, biotechnology concerns and other high-tech
               companies.

       (w)     SoundView Technology Index is an unweighted index consisting of
               more than 100 technology companies.

       (x)     Morgan Stanley High Tech 35 Index -- an index comprised of 
               thirty-five technology stocks chosen by Morgan Stanley.

       (y)     Pacific Stock Exchange Index -- an index consisting of
               approximately 100 technology and healthcare technology concerns.

     In assessing such comparisons of performance an investor should keep in
mind that the composition of the investments in the reported indices and
averages is not identical to the composition of investments in the Portfolio,
that the averages are generally unmanaged, and that the items included in the
calculations of such averages may not be identical to the formula used by the
Fund to calculate its futures.  In addition, there can be no assurance that the
Fund will continue this performance as compared to such other averages.


                               GENERAL INFORMATION

DESCRIPTION OF SHARES AND VOTING RIGHTS

     The Fund's Articles of Incorporation, as amended and restated, permit the
Directors to issue 35 billion shares of common stock, par value $.001 per share,
from an unlimited number of classes ("Portfolios") of shares.  Currently the
Fund consists of shares of twenty-nine Portfolios (the China Growth, MicroCap 
and Mortgage-Backed Securities Portfolios are not currently offering shares).

     The shares of each Portfolio of the Fund are fully paid and nonassessable,
and have no preference as to conversion, exchange, dividends, retirement or
other features.  The shares of each Portfolio of the Fund have no pre-emptive
rights.  The shares of the Fund have non-cumulative voting rights, which means
that the holders of more than 50% of the shares voting for the election of
Directors can elect 100% of the Directors if they choose to do so.  A
shareholder is entitled to one vote for each full share held (and a fractional
vote for each fractional share held), then standing in his name on the books of
the Fund.


                                       29
<PAGE>


DIVIDENDS AND CAPITAL GAINS DISTRIBUTIONS

     The Fund's policy is to distribute substantially all of the Portfolio's net
investment income, if any.  The Fund may also distribute any net realized
capital gains in the amount and at the times that will avoid both income
(including taxable gains) taxes on it and the imposition of the federal excise
tax on income and capital gains (see discussion under "Taxes" in this Statement
of Additional Information).  However, the Fund may also choose to retain net
realized capital gains and pay taxes on such gains.  The amounts of any income
dividends or capital gains distributions cannot be predicted.

     Any dividend or distribution paid shortly after the purchase of shares of
the Portfolio by an investor may have the effect of reducing the per share net
asset value of the Portfolio by the per share amount of the dividend or
distribution.  Furthermore, such dividends or distributions, although in effect
a return of capital, are subject to income taxes for shareholders subject to tax
as set forth herein and in the Prospectus.

     As set forth in the Prospectus, unless the shareholder elects otherwise in
writing, all dividends and capital gains distributions for a class of shares are
automatically received in additional shares of such class of the Portfolio at
net asset value (as of the business day following the record date).  This
automatic reinvestment of dividends and distributions will remain in effect
until the Fund is notified by the shareholder in writing at least three days
prior to the record date that either the Income Option (income dividends in cash
and capital gains distributions in additional shares at net asset value) or the
Cash Option (both income dividends and capital gains distributions in cash) has
been elected.

CUSTODY ARRANGEMENTS

     Chase is the Fund's custodian for domestic and certain foreign assets.  
Chase is not affiliated with Morgan Stanley & Co. Incorporated.  Morgan 
Stanley Trust Company, Brooklyn, NY, acts as the Fund's custodian for foreign 
assets held outside the United States and employs subcustodians who were 
approved by the Directors of the Fund in accordance with Rule 17f-5 adopted 
by the Commission under the 1940 Act. Morgan Stanley Trust Company is an 
affiliate of Morgan Stanley & Co. Incorporated.  In the selection of foreign 
subcustodians, the Directors consider a number of factors, including, but not 
limited to, the reliability and financial stability of the institution, the 
ability of the institution to provide efficiently the custodial services 
required for the Fund, and the reputation of the institution in the 
particular country or region.

                          DESCRIPTION OF RATINGS

I.  DESCRIPTION OF COMMERCIAL PAPER AND BOND RATINGS

     EXCERPTS FROM MOODY'S INVESTORS SERVICE, INC. ("MOODY'S") DESCRIPTION OF
BOND RATINGS:  Aaa - Bonds which are rated Aaa are judged to be the best
quality. They carry the smallest degree of investment risk and are generally
referred to as "gilt-edge." Interest payments are protected by a large or by an
exceptionally stable margin, and principal is secure.  While the various
protective elements are likely to change, such changes as can be visualized are
most unlikely to impair the fundamentally strong position of such issues.  Aa -
Bonds which are rated Aa are judged to be of high quality by all standards.
Together with the Aaa group they comprise what are generally known as high grade
bonds.  They are rated lower than the best bonds because margins of protection
may not be as large as in Aaa securities or fluctuation of protective elements
may be of greater amplitude or there may be other elements present which make
the long-term risks appear somewhat larger than in Aaa securities.  Moody's
applies numerical modifiers 1, 2 and 3 in the Aa and A rating categories.  The
modifier 1 indicates that the security ranks at a higher end of the rating
category, modifier 2 indicates a mid-range rating and the modifier 3 indicates
that the issue ranks at the lower end of the rating category.  A - Bonds which
are rated A possess many favorable investment attributes and are to be
considered as upper medium grade obligations.  Factors giving security to
principal and interest are considered adequate but elements may be present which
suggest a susceptibility to impairment sometime in the future.  Baa - Bonds
which are rated Baa are considered as medium grade obligations, i.e., they are
neither highly protected nor poorly secured. Interest payments and principal
security appear adequate for the present but certain protective elements may be
lacking or may be characteristically unreliable over any great length of time.
Such bonds lack outstanding investment characteristics and in fact have
speculative characteristics as well.  Ba - Bonds which are rated Ba are judged
to have speculative elements; their future cannot be considered as well assured.
Often the protection of interest and principal payments may be very moderate,
and thereby not well safeguarded during both good and bad times over the future.
Uncertainty of position characterizes bonds in this class.  B - Bonds which are
rated B generally lack characteristics of the desirable investment.  Assurance
of interest and principal payments or of maintenance of other terms of the
contract over any long period of time may be small.  Caa - Bonds which are rated
Caa are of poor standing.  Such issues may be in default or there may be present
elements of danger with respect


                                       30
<PAGE>


to principal or interest.  Ca - Bonds which are rated Ca represent obligations
which are speculative in a high degree.  Such issues are often in default or
have other marked shortcomings.
C - Bonds which are rated C are the lowest rated class of bonds, and issues so
rated can be regarded as having extremely poor prospects of ever attaining any
real investment standing.


     EXCERPTS FROM STANDARD & POOR'S RATINGS GROUP ("S&P") DESCRIPTION OF BOND
RATINGS: AAA - Bonds rated AAA have the highest rating assigned by Standard &
Poor's to a debt obligation and indicate an extremely strong capacity to pay
principal and interest.  AA - Bonds rated AA have a very strong capacity to pay
interest and repay principal and differ from the highest rated issues only to a
small degree.  A - Bonds rated A have a strong capacity to pay interest and
repay principal although they are somewhat more susceptible to the adverse
effects of changes in circumstances and economic conditions than bonds in higher
rated categories.  BBB - Debt rated BBB is regarded as having an adequate
capacity to pay interest and repay principal.  Whereas it normally exhibits
adequate protection parameters, adverse economic conditions or changing
circumstances are more likely to lead to a weakened capacity to pay interest and
repay principal for debt in this category than for debt in higher rated
categories.  BB, B, CCC, CC - Debt rated BB, B, CCC and CC is regarded, on
balance, as predominantly speculative with respect to capacity to pay interest
and repay principal in accordance with the terms of the obligation.  BB
indicates the lowest degree of speculation and CC the highest degree of
speculation.  While such debt will likely have some quality and protective
characteristics, these are outweighed by large uncertainties or major risk
exposures to adverse conditions.  C - The rating C is reserved for income bonds
on which no interest is being paid.  D - Debt rated D is in default, and payment
of interest and/or repayment of principal is in arrears.

     DESCRIPTION OF MOODY'S RATINGS OF STATE AND MUNICIPAL NOTES:  Moody's
ratings for state and municipal notes and other short-term obligations are
designated Moody's Investment Grade ("MIG").  Symbols used are as follows:
MIG-1 -- best quality, enjoying strong protection from established cash flows of
funds for their servicing or from established broad-based access to the market
for refinancing, or both; MIG-2 -- high quality with margins of protection ample
although not so large as in the preceding group; MIG-3 - favorable quality, with
all security elements accounted for but lacking the undeniable strength of the
preceding grades.

     DESCRIPTION OF MOODY'S HIGHEST COMMERCIAL PAPER RATING:  Prime-1 ("P1") --
Judged to be of the best quality.  Their short-term debt obligations carry the
smallest degree of investment risk.

     EXCERPT FROM S&P'S RATING OF MUNICIPAL NOTE ISSUES:  S-1+ -- very strong
capacity to pay principal and interest; SP-2 -- strong capacity to pay principal
and interest.

     DESCRIPTION OF S&P'S HIGHEST COMMERCIAL PAPER RATINGS:  A-1+ -- this
designation indicates the degree of safety regarding timely payment is
overwhelming.  A-1 -- this designation indicates the degree of safety regarding
timely payment is very strong.

<PAGE>

                               FINANCIAL STATEMENTS
   
     The Portfolio's audited financial statements for the fiscal period ended
December 31, 1996, including notes thereto and the report of 
Price Waterhouse LLP are herein incorporated by reference from the Fund's 
Annual Report. A copy of the Funds's Annual Report to Shareholders must 
accompany the delivery of this Statement of Additional Information.
    


                                       31

<PAGE>

                                     PART C

                     Morgan Stanley Institutional Fund, Inc.
                                Other Information




ITEM 24.  FINANCIAL STATEMENTS AND EXHIBITS

     (A)  FINANCIAL STATEMENTS
          --------------------

          1.   INCLUDED IN PART A (PROSPECTUSES)

   
               The Registrant's audited financial highlights for the Money 
               Market, Municipal Money Market, Aggressive Equity, Emerging 
               Growth, Equity Growth, Value Equity, Small Cap Value Equity, 
               U.S. Real Estate, Balanced, Active Country Allocation, Global 
               Equity, International Equity, International Small Cap, 
               European Equity, Asian Equity, Emerging Markets, Gold, 
               Japanese Equity, Latin American, Emerging Markets Debt, Fixed 
               Income, Global Fixed Income, High Yield, Municipal Bond, 
               Technology and International Magnum Portfolios, respectively, 
               as of December 31, 1996, are included in 
               the prospectuses of the foregoing portfolios in Part A.
               The Fund's Mortgage-Backed Securities, China Growth and MicroCap
               Portfolios were not operational as of December 31, 1996. 
               Accordingly, no audited financial highlights are included in the
               respective prospectus of each of the foregoing portfolios.
    
          2.   INCORPORATED BY REFERENCE INTO PART B (STATEMENT OF ADDITIONAL
               INFORMATION)

   
               The Registrant's audited financial statements for the Money 
               Market, Municipal Money Market, Aggressive Equity, Emerging 
               Growth, Equity Growth, Value Equity, Small Cap Value Equity, 
               U.S. Real Estate, Balanced, Active Country Allocation, Global 
               Equity, International Equity, International Small Cap, 
               European Equity, Asian Equity, Emerging Markets, Gold, 
               Japanese Equity, Latin American, Emerging Markets Debt, Fixed 
               Income, Global Fixed Income, High Yield, Municipal Bond and 
               International Magnum Portfolios, respectively, as of 
               December 31, 1996, including Price Waterhouse LLP's 
               report thereon, are hereby incorporated by reference to the 
               Statement of Additional Information from Form N-30D, the Annual
               Report to Shareholders, as filed with the Securities and 
               Exchange Commission on March 11, 1997 with Accession Number 
               0000912057-97-008473. 

               The financial statements included in Part B are:

                1. Statement of Net Assets
                2. Statement of Operations
                3. Statement of Changes in Net Assets
                4. Statement of Cash Flows (Emerging Markets Debt Portfolio 
                   only)
                5. Financial Highlights
                6. Notes to Financial Statements
                7. Report of Independent Accountants

    
   
               The Fund's Mortgage-Backed Securities, China Growth and MicroCap
               Portfolios were not operational as of December 31, 1996.
               Accordingly, no audited financial statements are included in the
               Statement of Additional Information.

               The Registrant's audited financial statements for the Technology
               Portfolio as of December 31, 1996, including 
               Price Waterhouse LLP's report thereon, are hereby 
               incorporated by reference to the Statement of Additional 
               Information from Form N-30D, the Annual Report to 
               Shareholders, as filed with the Securities and 
               Exchange Commission on March 11, 1997 with Accession Number 
               0000912057-97-008473.

               The financial statements included in Part B are:

                1. Statement of Net Assets
                2. Statement of Operations
                3. Statement of Changes in Net Assets
                4. Financial Highlights
                5. Notes to Financial Statements
                6. Report of Independent Accountants

    
<PAGE>


     (B)  EXHIBITS
          --------

     1    (a)  Articles of Amendment and Restatement are incorporated by
               reference to Post-Effective Amendment No. 26 to the Registrant's
               Registration Statement on Form N-1A (File Nos. 33-23166 and 811-
               5624), as filed with the SEC via EDGAR on October 13, 1995.


          (b)  Articles Supplementary to Registrant's Articles of Incorporation
               (reclassifying shares) is incorporated by reference to 
               Post-Effective Amendment No. 30 to the Registrant's Registration
               Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
               filed with the SEC via EDGAR on May 24, 1996.

          (c)  Articles Supplementary to Registrant's Articles of Incorporation
               (adding new Technology Portfolio) is incorporated by reference 
               to Post-Effective Amendment No. 30 to the Registrant's
               Registration Statement on Form N-1A (File Nos. 33-23166 and
               811-5624), as filed with the SEC via EDGAR on May 24, 1996.


     2    Amended and Restated By-laws are incorporated by reference to 
          Post-Effective Amendment No. 33 to the Registrant's Registration 
          Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as filed
          with the SEC via EDGAR on February 28, 1997.

     3    Not Applicable.

     4    Registrant's Form of Specimen Security was previously filed and is
          incorporated herein by reference.

     5    (a)  Investment Advisory Agreement between Registrant and Morgan
               Stanley Asset Management Inc. is incorporated by reference to
               Post-Effective Amendment No. 25 to the Registrant's Registration
               Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
               filed with the SEC via EDGAR on August 1, 1995.

          (b)  Supplement to Investment Advisory Agreement between Registrant
               and Morgan Stanley Asset Management Inc.  (adding Registrant's
               Value Equity, Balanced and Fixed Income Portfolios) is
               incorporated by reference to Post-Effective Amendment No. 25 to
               the Registrant's Registration Statement on Form N-1A (File Nos.
               33-23166 and 811-5624), as filed with the SEC via EDGAR on August
               1, 1995.

          (c)  Supplement to Investment Advisory Agreement between Registrant
               and Morgan Stanley Asset Management Inc. (adding the Global
               Equity, Global Fixed Income, European Equity and Equity Growth
               Portfolios) is incorporated by reference to Post-Effective
               Amendment No. 25 to the Registrant's Registration Statement on
               Form N-1A (File Nos. 33-23166 and 811-5624), as filed with the
               SEC via EDGAR on August 1, 1995.

          (d)  Supplement to Investment Advisory Agreement between Registrant
               and Morgan Stanley Asset Management Inc. (adding the Asian Equity
               Portfolio) is incorporated by reference to Post-Effective
               Amendment No. 25 to the Registrant's Registration Statement on
               Form N-1A (File Nos. 33-23166 and 811-5624), as filed with the
               SEC via EDGAR on August 1, 1995.

          (e)  Supplement to Investment Advisory Agreement between Registrant
               and Morgan Stanley Asset Management Inc. (adding the Active
               Country Allocation Portfolio) is incorporated by reference to
               Post-Effective Amendment No. 25 to the Registrant's Registration
               Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
               filed with the SEC via EDGAR on August 1, 1995.


          (f)  Supplement to Investment Advisory Agreement between Registrant
               and Morgan Stanley Asset Management Inc. (adding the Emerging
               Markets, High Yield and International Small Cap Portfolios) is
               incorporated by reference to Post-Effective Amendment No. 25 to
               the Registrant's Registration Statement on Form N-1A (File Nos.
               33-23166 and 811-5624), as filed with the SEC via EDGAR on August
               1, 1995.

          (g)  Supplement to Investment Advisory Agreement between Registrant
               and Morgan Stanley Asset Management Inc. (adding the Small Cap
               Value Equity Portfolio) is incorporated by reference to Post-
               Effective Amendment No. 25 to the Registrant's Registration
               Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
               filed with the SEC via EDGAR on August 1, 1995.

                                        C-2

<PAGE>

          (h)  Supplement to Investment Advisory Agreement between Registrant
               and Morgan Stanley Asset Management Inc. (adding the Emerging
               Markets Debt, Mortgage-Backed Securities, Municipal Bond and
               Japanese Equity Portfolios) is incorporated by reference to Post-
               Effective Amendment No. 25 to the Registrant's Registration
               Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
               filed with the SEC via EDGAR on August 1, 1995.

          (i)  Sub-Advisory Agreement among Registrant, Morgan Stanley Asset
               Management Inc. and Sun Valley Gold Company (with respect to the
               Gold Portfolio) is incorporated by reference to Post-Effective
               Amendment No. 25 to the Registrant's Registration Statement on
               Form N-1A (File Nos. 33-23166 and 811-5624), as filed with the
               SEC via EDGAR on August 1, 1995.

          (j)  Supplement to Investment Advisory Agreement between Registrant
               and Morgan Stanley Asset Management Inc. (adding the China Growth
               Portfolio) is incorporated by reference to Post-Effective
               Amendment No. 25 to the Registrant's Registration Statement on
               Form N-1A (File Nos. 33-23166 and 811-5624), as filed with the
               SEC via EDGAR on August 1, 1995.

          (k)  Supplement to Investment Advisory Agreement between Registrant
               and Morgan Stanley Asset Management Inc. (adding the Latin
               American Portfolio) is incorporated by reference to Post-
               Effective Amendment No. 25 to the Registrant's Registration
               Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
               filed with the SEC via EDGAR on August 1, 1995.

          (l)  Withdrawn.

          (m)  Supplement to Investment Advisory Agreement between Registrant
               and Morgan Stanley Asset Management Inc. (adding the Aggressive
               Equity and U.S. Real Estate Portfolios) is incorporated by
               reference to Post-Effective Amendment No. 25 to the Registrant's
               Registration Statement on Form N-1A (File Nos. 33-23166 and 811-
               5624), as filed with the SEC via EDGAR on August 1, 1995.

          (n)  Supplement to Investment Advisory Agreement between Registrant
               and Morgan Stanley Asset Management Inc. (adding the MicroCap
               Portfolio) is incorporated by reference to Post-Effective
               Amendment No. 25 to the Registrant's Registration Statement on
               Form N-1A (File Nos. 33-23166 and 811-5624), as filed with the
               SEC via EDGAR on August 1, 1995.

          (o)  Supplement to Investment Advisory Agreement between Registrant
               and Morgan Stanley Asset Management Inc. (adding the
               International Magnum Portfolio) is incorporated by reference to
               Post-Effective Amendment No. 28 to the Registrant's Registration
               Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
               filed with the SEC via EDGAR on November 3, 1995.

   
          (p)  Supplement to Investment Advisory Agreement between
               Registrant and Morgan Stanley Asset Management Inc. (adding the
               Technology Portfolio), is incorporated by reference to 
               Post-Effective Amendment No. 33 to the Registrant's 
               Registration Statement on Form N-1A (File Nos. 33-23166 and 
               811-5624), as filed with the SEC via EDGAR on February 28, 1997.
    

     6    (a)  Distribution Agreement between Registrant and Morgan Stanley &
               Co. Incorporated is incorporated by reference to Post-Effective
               Amendment No. 25 to the Registrant's Registration Statement on
               Form N-1A (File Nos. 33-23166 and 811-5624), as filed with the
               SEC via EDGAR on August 1, 1995.

          (b)  Supplement to Distribution Agreement between Registrant and
               Morgan Stanley & Co. Incorporated is incorporated by reference to
               Post-Effective Amendment No. 29 to the Registrant's Registration
               Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
               filed with the SEC via EDGAR on April 29, 1996.

     8    (a)  Mutual Fund Custody Agreement (Domestic Custody Agreement)
               between Registrant and United States Trust Company of New York
               dated March 10, 1994 is incorporated by reference to Post-
               Effective Amendment No. 25 to the Registrant's Registration
               Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
               filed with the SEC via EDGAR on August 1, 1995.

          (b)  Registrant's Custody Agreement (International), dated July 31,
               1989, as amended is incorporated by reference to Post-Effective
               Amendment No. 25 to the Registrant's Registration Statement on
               Form N-1A (File Nos. 33-23166 and 811-5624), as filed with the
               SEC via EDGAR on August 1, 1995.


                                        C-3

<PAGE>

          (c)  Amendment dated April 22, 1996 to Registrant's Custody Agreement
               (International), dated July 31, 1989, is incorporated by 
               reference to Post-Effective Amendment No. 30 to the Registrant's
               Registration Statement on Form N-1A (File Nos. 33-23166 and
               811-5624) as filed with the SEC via EDGAR on May 24, 1996.

     9    (a)  Administration Agreement between Registrant and Morgan Stanley
               Asset Management Inc. (the "MSAM Administration Agreement") is
               incorporated by reference to Post-Effective Amendment No. 25 to
               the Registrant's Registration Statement on Form N-1A (File Nos.
               33-23166 and 811-5624), as filed with the SEC via EDGAR on August
               1, 1995.

          (b)  U.S. Trust Administration Agreement is incorporated by reference
               to Post-Effective Amendment No. 25 to the Registrant's
               Registration Statement on Form N-1A (File Nos. 33-23166 and 811-
               5624), as filed with the SEC via EDGAR on August 1, 1995.

     10   Opinion of Counsel is incorporated by reference to Post-Effective
          Amendment No. 25 to the Registrant's Registration Statement on Form N-
          1A (File Nos. 33-23166 and 811-5624), as filed with the SEC via EDGAR
          on August 1, 1995.

   
     11   Consent of Independent Accountants is filed herewith.

    

     13   Purchase Agreement is incorporated by reference to Post-Effective
          Amendment No. 25 to the Registrant's Registration Statement on Form N-
          1A (File Nos. 33-23166 and 811-5624), as filed with the SEC via EDGAR
          on August 1, 1995.

   
     15   Plan of Distribution Pursuant to Rule 12b-1 for Class B Shares
          (the "Class B Plan") of the Active Country Allocation Portfolio is
          incorporated by reference to Post-Effective Amendment No. 33 to the
          Registrant's Registration Statement on Form N-1A (File Nos. 33-23166
          and 811-5624), as filed with the SEC via EDGAR on February 28, 1997.
          The following Class B Plans have been omitted because
          they are substantially identical to the one incorporated by reference
          herein.  The omitted Class B Plans differ from the Class B Plan
          incorporated by reference herein only with respect to the portfolio
          to which the Class B Plan relates:  Fixed Income, Global Fixed Income,
          Municipal Bond, Mortgage-Backed Securities, High Yield, Money Market,
          Municipal Money Market, Small Cap Value Equity, Value Equity,
          Balanced, Gold, Global Equity, International Equity, International
          Small Cap, Asian Equity, European Equity, Japanese Equity, Latin
          American, Emerging Markets, Emerging Markets Debt, China Growth,
          Equity Growth, Emerging Growth, MicroCap, Aggressive Equity, U.S. Real
          Estate, International Magnum and Technology Portfolios.
    

     16   Schedule of Computation of Performance Information is incorporated by
          reference to Post-Effective Amendment No. 25 to the Registrant's
          Registration Statement on Form N-1A (File Nos. 33-23166 and 811-5624),
          as filed with the SEC via EDGAR on August 1, 1995.

   
     19   Registrant's Rule 18f-3 Multiple Class Plan is incorporated by
          reference to Post-Effective Amendment No. 33 to the Registrant's 
          Registration Statement on Form N-1A (File Nos. 33-23166 and 
          811-5624), as filed with the SEC via EDGAR on February 28, 1997.

    
   
     24   Powers of Attorney are incorporated by reference to Post-Effective
          Amendment No. 25 to the Registrant's Registration Statement on Form N-
          1A (File Nos. 33-23166 and 811-5624), as filed with the SEC via EDGAR
          on August 1, 1995.

     27   Financial data schedules for the fiscal  year ended December 31, 1996
          for Registrant's portfolios in operation during such period (See 
          Item 24(a)), are filed herewith.

    

ITEM 25.  PERSONS CONTROLLED BY OR UNDER COMMON CONTROL WITH REGISTRANT



          Registrant is not controlled by or under common control with any
          person.

   
ITEM 26.  NUMBER OF HOLDERS OF SECURITIES (ON MARCH 31, 1997)
    

     Active Country Allocation Portfolio
   
          Class A. . . . . . . . . . . . . . . . . . .        68
    
   
          Class B. . . . . . . . . . . . . . . . . . .        23
    
                                        C-4

<PAGE>

     Aggressive Equity Portfolio
   
          Class A. . . . . . . . . . . . . . . . . . .        424
    
   
          Class B. . . . . . . . . . . . . . . . . . .        79
    
   
     Asian Equity Portfolio
          Class A. . . . . . . . . . . . . . . . . . .        1,164
    
   
          Class B. . . . . . . . . . . . . . . . . . .        84
     Balanced Portfolio
    
   
          Class A. . . . . . . . . . . . . . . . . . .        60
    
   
          Class B. . . . . . . . . . . . . . . . . . .        14
    
   
     Emerging Growth Portfolio
          Class A. . . . . . . . . . . . . . . . . . .        190
    
   
          Class B. . . . . . . . . . . . . . . . . . .        32
    
   
     Emerging Markets Portfolio
          Class A. . . . . . . . . . . . . . . . . . .        1,538
    
   
          Class B. . . . . . . . . . . . . . . . . . .        119
    
   
     Equity Growth Portfolio
          Class A. . . . . . . . . . . . . . . . . . .        741
    
   
          Class B. . . . . . . . . . . . . . . . . . .        57
    
   
     Fixed Income Portfolio
          Class A. . . . . . . . . . . . . . . . . . .        194
    
   
          Class B. . . . . . . . . . . . . . . . . . .        28
    
   
     Global Equity Portfolio
          Class A. . . . . . . . . . . . . . . . . . .        98
    
   
          Class B. . . . . . . . . . . . . . . . . . .        24
    
   
     Global Fixed Income Portfolio
          Class A. . . . . . . . . . . . . . . . . . .        235
    
   
          Class B. . . . . . . . . . . . . . . . . . .        12
    
   
     High Yield Portfolio
          Class A. . . . . . . . . . . . . . . . . . .        638
    
   
          Class B. . . . . . . . . . . . . . . . . . .        54
    
   
     International Equity Portfolio
          Class A. . . . . . . . . . . . . . . . . . .        426
    
   
          Class B. . . . . . . . . . . . . . . . . . .        50
    
   
     International Small Cap Portfolio
          Class A. . . . . . . . . . . . . . . . . . .        148
    
   
     Latin American Portfolio
          Class A. . . . . . . . . . . . . . . . . . .        778
    
   
          Class B. . . . . . . . . . . . . . . . . . .        31
    
   
     Money Market Portfolio
          Class A. . . . . . . . . . . . . . . . . . .        624
    
   
     Municipal Money Market Portfolio
          Class A. . . . . . . . . . . . . . . . . . .        307
    
   
     Small Cap Value Equity Portfolio
          Class A. . . . . . . . . . . . . . . . . . .        495
    
   
          Class B. . . . . . . . . . . . . . . . . . .        19
    
   
     U.S. Real Estate Portfolio
          Class A. . . . . . . . . . . . . . . . . . .        816
    
   
          Class B. . . . . . . . . . . . . . . . . . .        60
    
   
     Value Equity Portfolio
          Class A. . . . . . . . . . . . . . . . . . .        553
    
   
          Class B. . . . . . . . . . . . . . . . . . .        23
    
   
     European Equity Portfolio
          Class A. . . . . . . . . . . . . . . . . . .        795
    
   
          Class B. . . . . . . . . . . . . . . . . . .        35
    
   
     Municipal Bond Portfolio
          Class A. . . . . . . . . . . . . . . . . . .        92
    
   
          Class B. . . . . . . . . . . . . . . . . . .        2
     Mortgage-Backed Securities Portfolio
    


                                        C-5


<PAGE>

   
          Class A. . . . . . . . . . . . . . . . . . .      0
    
   
          Class B. . . . . . . . . . . . . . . . . . .      0
    
   
     Japanese Equity Portfolio
          Class A. . . . . . . . . . . . . . . . . . .      792
    
   
          Class B. . . . . . . . . . . . . . . . . . .      33
    
   

     Emerging Markets Debt Portfolio
          Class A. . . . . . . . . . . . . . . . . . .      578
    
   
          Class B. . . . . . . . . . . . . . . . . . .      29
    
   
     Gold Portfolio
          Class A. . . . . . . . . . . . . . . . . . .      610
    
   
          Class B. . . . . . . . . . . . . . . . . . .      25
    
   
     China Growth Portfolio
          Class A. . . . . . . . . . . . . . . . . . .      0
    
   
          Class B. . . . . . . . . . . . . . . . . . .      0
    
   
     MicroCap Portfolio
          Class A. . . . . . . . . . . . . . . . . . .      0
    
   
          Class B. . . . . . . . . . . . . . . . . . .      0
    
   
     International Magnum Portfolio
          Class A. . . . . . . . . . . . . . . . . . .      52
    
   
          Class B. . . . . . . . . . . . . . . . . . .      26
    
   
     Technology Portfolio
          Class A. . . . . . . . . . . . . . . . . . .      36
    
   
          Class B. . . . . . . . . . . . . . . . . . .      19
    

ITEM 27.  INDEMNIFICATION

          Reference is made to Article TEN of the Registrant's Articles of
Incorporation.  Insofar as indemnification for liability arising under the
Securities Act of 1933 may be permitted to trustees, officers and controlling
persons of the registrant pursuant to the foregoing provisions, or otherwise,
the registrant has been advised that in the opinion of the Securities and
Exchange Commission such indemnification is against public policy as expressed
in the Act and is, therefore, unenforceable.  In the event that a claim for
indemnification against such liabilities (other than the payment by the
registrant of expenses incurred or paid by a trustee, officer or controlling
person of the registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the registrant will, unless in
the opinion of its counsel the matter has been settled by controlling precedent,
submit to a court of appropriate jurisdiction the question whether such
indemnification by it is against public policy as expressed in the Act and will
be governed by the final adjudication of such issue.

ITEM 28.  BUSINESS AND OTHER CONNECTIONS WITH INVESTMENT ADVISER
   
          Reference is made to the caption "Investment Adviser" in the
Prospectuses constituting Part A of this Registration Statement Information
required by this item with respect to each Officer or Director of the Advisor,
together with information as to any other business, profession, vocation or
employment of a substantial nature engaged in by such Officers and Directors
during the past two years is incorporated by reference to Schedules A and D
of Form ADV filed by the Advisors Act (SEC File No. 801-15757).

          Listed below are the officers and Directors of Morgan Stanley Asset
Management Inc. ("MSAM").

    

   
DIRECTORS

James M. Allwin                   Director
Barton M. Biggs                   Director
Gordon S. Gray                    Director
Peter A. Nadosy                   Director
Dennis G. Sherva                  Director


OFFICERS

Barton M. Biggs                   Chairman 
                                  Managing Director
Peter A. Nadosy                   Vice Chairman
                                  Managing Director
James M. Allwin                   President
                                  Managing Director
John R. Alkire                    Managing Director (MSAM) - Toyko
P. Dominic Caldecott              Managing Director (MSAM) - UK
A. Macdonald Caputo               Managing Director
Ean Wah Chin                      Managing Director (MSAM) -
                                   Singapore
Garry B. Crowder                  Managing Director
Madhav Dhar                       Managing Director
Kurt A. Feuerman                  Managing Director
Paul B. Ghaffari                  Managing Director
Gordon S. Gray                    Managing Director
Marianne Laing Hay                Managing Director (MSAM) - UK
Gary D. Latainer                  Managing Director
Mahmoud A. Mamdani                Managing Director
Robert L. Meyer                   Managing Director
Russell C. Platt                  Managing Director
Robert A. Sargent                 Managing Director (MSAM) - UK
Bidyut C. Sen                     Managing Director
Vinod R. Sethi                    Managing Director
Dennis G. Sherva                  Managing Director
James L. Tanner                   Managing Director (MSAM) - UK
Richard G. Woolworth, Jr.         Managing Director
Debra M. Aaron                    Principal
Warren Ackerman III               Principal
Robert E. Angevine                Principal
Suzanne S. Akers                  Principal
Gerald P. Barth-Wehrenalp         Principal
Theodore R. Bigman                Principal
Francine J. Bovich                Principal
Stuart J. M. Breslow              Principal
Andrew C. Brown                   Principal (MSAM) - UK
Jeffrey P. Brown                  Principal
Frances Campion                   Principal (MSAM) - UK
Terence P. Carmichael             Principal
Arthur Certosimo                  Principal


                                      C-6

<PAGE>

Stephen C. Cordy                  Principal
Jacqueline A. Day                 Principal (MSAM) - UK
Raye L. Dube                      Principal
Abigail Jones Feder               Principal
Eugene Flood, Jr.                 Principal
Thomas C. Frame                   Principal
James Wayne Grisham               Principal
Perry E. Hall II                  Principal
Ruth A. Hughes-Guden              Principal
Margaret Kinsley Johnson          Principal
Michael F. Klein                  Principal
Michael B. Kushma                 Principal
Khoon-Min Lim                     Principal
Marianne J. Lippmann              Principal
Yvonne Longley                    Principal (MSAM) - UK
Andrew Mack                       Principal (MSAM) - UK
Gary J. Mangino                   Principal
Jeffrey Margolis                  Principal
M. Paul Martin                    Principal
Walter Maynard, Jr.               Principal
Margaret P. Naylor                Principal (MSAM) - UK
Yoshiro Okawa                     Principal (MSAM) - Tokyo
Warren Olsen                      Principal
Christopher G. Petrow             Principal
Narayan Ramachandran              Principal
Gail Hunt Reeke                   Principal
Christine I. Reilly               Principal
Stefano Russo                     Principal (MSAM) - Milan
Bruce R. Sandberg                 Principal
Kiat Seng Seah                    Principal (MSAM) - Singapore
Stephen C. Sexauer                Principal
Robert M. Smith                   Principal
Kunihiko Sugio                    Principal (MSAM) - Tokyo
Ann D. Thivierge                  Principal
Philip W. Winters                 Principal
Alford E. Zick, Jr.               Principal
Maryann Savadelis Agre            Vice President
Peter Aliprantis                  Vice President
Jeffrey Alvino                    Vice President
Alistair Anderson                 Vice President
William S. Auslander              Vice President
Kimberly L. Austin                Vice President
Marshall T. Bassett               Vice President
Christopher Blair                 Vice President
Richard Boon                      Vice President
Geraldine Boyle                   Vice President
Paul Boyne                        Vice President
L. Kenneth Brooks                 Vice President
Jonathan Paul Buckeridge          Vice President (MSAM) - Melbourne
Carl Kuo-Wei Chien                Vice President (MSAM) - Hong Kong
Lori A. Cohane                    Vice President
James Colmenares                  Vice President
Kate Cornish-Bowden               Vice President (MSAM) - UK
Nikhil Dhaon                      Vice President
Christine H. du Bois              Vice President
Richard S. Farden                 Vice President
Daniel E. Fox                     Vice President
Karen T. Frost                    Vice President (MSAM) - UK
Lisa Gallo                        Vice President
Josephine M. Glass                Vice President
Charles A. Golden                 Vice President
Dimitri Goulandris                Vice President
James A. Grasselino               Vice President


                                      C-7

<PAGE>

Kenneth John Greig                Vice President (MSAM) - UK
Maureen A. Grover                 Vice President
Michael Hewett                    Vice President
Kenneth R. Holley                 Vice President
Holly D. Hopps                    Vice President
Etsuko Fuseya Jennings            Vice President
Donald B. Johnston                Vice President
Jaideep Khanna                    Vice President
Peter L. Kirby                    Vice President
George Koshy                      Vice President
Paul Koske                        Vice President
Daniel R. Lascano                 Vice President
Arthur J. Lev                     Vice President
Valerie Y. Lewis                  Vice President
Jane Likins                       Vice President (MSAM) - UK
William David Lock                Vice President (MSAM) - UK
Gordon W. Loery                   Vice President
Paula J. Morgan                   Vice President (MSAM) - UK
Nancy Morton                      Vice President
Clare K. Mutone                   Vice President
Terumi Nagata                     Vice President (MSAM) - Tokyo
Bradley Okita                     Vice President
Martin O. Pearce                  Vice President (MSAM) - UK
Alexander A. Pena                 Vice President
Anthony J. Pesce                  Vice President
David J. Polansky                 Vice President
Karen Post                        Vice President
Akash Prakash                     Vice President (MSAM) - Muabai
Gregg A. Robinson                 Vice President
Gerald D. Rubin                   Vice President
Donald P. Ryan                    Vice President
Neil Siegel                       Vice President
Ashutosh Sinha                    Vice President
Andy B. Skov                      Vice President
Michael James Smith               Vice President (MSAM) - UK
Kim I. Spellman                   Vice President
Joseph P. Stadler                 Vice President
Christian K. Stadlinger           Vice President
Catherine Steinhardt              Vice President
Ram K. Sundaram                   Vice President
Keiko Tamaki-Kuroda               Vice President
Shunso Tatsumi                    Vice President
Louise Teeple                     Vice President
Joseph Y.S. Tern                  Vice President (MSAM) Singapore
Landon Thomas                     Vice President
Richard Boon Hwee Toh             Vice President (MSAM) Singapore
K.N. Vaidyanathan                 Vice President (MSAM) Muabai
Dennis J. Walsh                   Vice President
Jacob Walthour                    Vice President
Kevin V. Wasp                     Vice President
Patricia Woo                      Vice President
Harold J. Schaaff, Jr.            Principal
                                  General Counsel and Secretary 
Eileen K. Murray                  Treasurer
Madeline D. Barkhorn              Assistant Secretary
Charlene R. Herzer                Assistant Secretary
    
   
          In addition, MSAM acts as investment adviser to the following
registered investment companies:  American Advantage International Equity Fund;
The Brazilian Investment Fund, Inc.; certain portfolios of The Enterprise Group
of Funds, Inc.; Fountain Square International Equity Fund; General American
Capital Co.; The Latin American Discovery Fund, Inc.; certain portfolios of The
Legends Fund, Inc.; The Malaysia Fund, Inc.; Morgan Stanley Africa Investment
Fund, Inc.; Morgan Stanley Asia-Pacific Fund, Inc.; Morgan Stanley Emerging
Markets Debt Fund, Inc.; Morgan Stanley Emerging Markets Fund, Inc.; all funds
of the Morgan Stanley Fund, Inc.; Morgan Stanley Global Opportunity Bond Fund,
Inc.; all funds of The Morgan Stanley High Yield Fund, Inc.; Morgan Stanley
India Investment Fund, Inc.; certain portfolios of Morgan Stanley Universal 
Funds, Inc.; The Pakistan Investment
    
                                        C-8

<PAGE>

Fund, Inc.;  PCS Cash Fund, Inc.; The Thai Fund, Inc.; The Turkish Investment
Fund, Inc.; Principal Aggressive Growth Fund, Inc.; Principal Asset Allocation
Fund, Inc.; certain portfolios of the SunAmerica Series Trust and certain
portfolios of the Fortis Series Fund.

ITEM 29.  PRINCIPAL UNDERWRITERS
          ----------------------
   
          Morgan Stanley & Co. Incorporated ("MS&Co.") is distributor for Morgan
Stanley Institutional Fund, Inc. The information required by this Item 29 with
respect to each Director and officer of MS&Co. is incorporated by reference to
Schedule A of Form BD filed by MS&Co. pursuant to the Securities and
Exchange Act of 1934 (SEC File No. 8-15869).
    
ITEM 30.  LOCATION OF ACCOUNTS AND RECORDS
          --------------------------------

          The books, accounts and other documents required by Section 31(a)
under the Investment Company Act of 1940 and the rules promulgated thereunder
are maintained in the physical possession of the Registrant; Registrant's
Transfer Agent, Chase Global Funds Services Company, P.O. Box 2798, 
Boston, Massachusetts  02208-2798; MSAM; MS&Co.; and the Registrant's 
custodian banks, including sub-custodians.

ITEM 31.  MANAGEMENT SERVICES
          -------------------

          The Registrant has entered into a Service Agreement with The Chase
Manhattan Bank, successor in interest to United States Trust Company of
New York, which was filed as Exhibit No. 9(b) to Post-Effective Amendment No. 25
to the Fund's Registration Statement and is incorporated herein by reference.

ITEM 32.  UNDERTAKINGS
          ------------

   
          1.  Registrant hereby undertakes to file a post-effective amendment
containing reasonably current financial statements, which need not be certified,
for the China Growth, Mortgage-Backed Securities and MicroCap Portfolios within
four to six months of their effective date or the commencement of operations,
whichever is later.
    

          2.  Registrant hereby undertakes that whenever a Shareholder or
Shareholders who meet the requirements of Section 16(c) of the Investment
Company Act of 1940 inform the Board of Directors of his or their desire to
communicate with other Shareholders of the Fund, the Directors will inform such
Shareholder(s) as to the approximate number of Shareholders of record and the
approximate costs of mailing or afford said Shareholders access to a list of
Shareholders.

                                        C-9

<PAGE>

   
                                      SIGNATURES

         Pursuant to the requirements of the Securities Act of 1933, as amended,
and the Investment Company Act of 1940, as amended, the Registrant certifies 
that it meets all of the requirements for effectiveness of this Amendment to 
the Registration Statement pursuant to Rule 485(b) and has duly caused this 
Amendment to its Registration Statement to be signed on its behalf by the
undersigned, thereunto duly authorized, in the City of New York and State of
New York, on the 30th day of April, 1997. 
    
                              MORGAN STANLEY INSTITUTIONAL FUND, INC.

                              By:   /s/ Warren J. Olsen
                                   ----------------------------
                                   Warren J. Olsen
                                   President and Director


          Pursuant to the requirements of the Securities Act of 1933, as 
amended, this Amendment to the Registration Statement has been signed below
by the following persons in the capacities and on the dates indicated.


SIGNATURE                          TITLE                    DATE

   
/s/ Warren J. Olsen                Director, President      April 30, 1997
- -------------------------------    (Principal Executive
Warren J. Olsen                    Officer)
    

   
* /s/ Barton M. Biggs              Director (Chairman)      April 30, 1997
- -------------------------------
  Barton M. Biggs
    

   
* /s/ Fergus Reid                  Director                 April 30, 1997
- -------------------------------
  Fergus Reid
    

   
* /s/ Frederick D. Robertshaw      Director                 April 30, 1997
- -------------------------------
  Frederick O. Robertshaw
    

   
* /s/ Andrew McNally IV            Director                 April 30, 1997
- -------------------------------
  Andrew McNally IV
    

   
* /s/ John D. Barrett II           Director                 April 30, 1997
- -------------------------------
  John D. Barrett II
    

   
* /s/ Gerard E. Jones              Director                 April 30, 1997
- -------------------------------
  Gerard E. Jones
    

   
* /s/ Samuel T. Reeves             Director                 April 30, 1997
- -------------------------------
  Samuel T. Reeves
    

   
* /s/ James R. Rooney              Treasurer                April 30, 1997
- -------------------------------    (Principal
  James R. Rooney                  Accounting
                                   Officer)
*By: /s/ Warren J. Olsen
   ----------------------------
     Warren J. Olsen
     Attorney-In-Fact
    

<PAGE>

                                  EXHIBIT INDEX
                                  -------------

  EDGAR
  Exhibit
  Number                      Description

   
           1(a)     Articles of Amendment and Restatement are incorporated by
                    reference to Post-Effective Amendment No. 26 to the
                    Registrant's Registration Statement on Form N-1A (File Nos.
                    33-23166 and 811-5624), as filed with the SEC via EDGAR on
                    October 13, 1995.
    


            (b)     Articles Supplementary to Registrant's Articles of
                    Incorporation (reclassifying shares) is incorporated by 
                    reference to Post-Effective Amendment No. 30 to the
                    Registrant's Registration Statement on Form N-1A (File Nos.
                    33-23166 and 811-5624), as filed with the SEC via EDGAR on
                    May 24, 1996.

            (c)     Articles Supplementary to Registrant's Articles of 
                    Incorporation (adding new Technology Portfolio) is 
                    incorporated by reference to Post-Effective Amendment No.
                    30 to the Registrant's Registration Statement on Form N-1A
                    (File No. 33-23166 and 811-5624), as filed with the SEC via
                    EDGAR on May 24, 1996.


   

           2        Amended and Restated By-laws are incorporated by 
                    reference to Post-Effective Amendment No. 33 to the 
                    Registrant's Registration Statement on Form N-1A 
                    (File Nos. 33-23166 and 811-5624), as filed with the 
                    SEC via EDGAR on February 28, 1997.
    

           4        Registrant's Form of Specimen Security was previously filed
                    and is incorporated herein by reference.

   
           5   (a)  Investment Advisory Agreement between Registrant and Morgan
                    Stanley Asset Management Inc. is incorporated by reference
                    to Post-Effective Amendment No. 25 to the Registrant's
                    Registration Statement on Form N-1A (File Nos. 33-23166 and
                    811-5624), as filed with the SEC via EDGAR on August 1,
                    1995.
    

   
           5   (b)  Supplement to Investment Advisory Agreement between
                    Registrant and Morgan Stanley Asset Management Inc.  (adding
                    Registrant's Equity, Balanced and Fixed Income Portfolios)
                    is incorporated by reference to Post-Effective Amendment No.
                    25 to the Registrant's Registration Statement on Form N-1A
                    (File Nos. 33-23166 and 811-5624), as filed with the SEC via
                    EDGAR on August 1, 1995.
    

   
           5   (c)  Supplement to Investment Advisory Agreement between
                    Registrant and Morgan Stanley Asset Management Inc. (adding
                    the Global Equity, Global Fixed Income, European Equity and
                    Equity Growth Portfolios) is incorporated by reference to
                    Post-Effective Amendment No. 25 to the Registrant's
                    Registration Statement on Form N-1A (File Nos. 33-23166 and
                    811-5624), as filed with the SEC via EDGAR on August 1,
                    1995.
    

   
           5   (d)  Supplement to Investment Advisory Agreement between
                    Registrant and Morgan Stanley Asset Management Inc. (adding
                    the Asian Equity Portfolio) is incorporated by reference to
                    Post-Effective Amendment No. 25 to the Registrant's
                    Registration Statement on Form N-1A (File Nos. 33-23166 and
                    811-5624), as filed with the SEC via EDGAR on August 1,
                    1995.
    

   
           5   (e)  Supplement to Investment Advisory Agreement between
                    Registrant and Morgan Stanley Asset Management Inc. (adding
                    the Active Country Allocation Portfolio) is incorporated by
                    reference to Post-Effective Amendment No. 25 to the
                    Registrant's Registration Statement on Form 
    

<PAGE>

                    N-1A (File Nos. 33-23166 and 811-5624), as filed with the 
                    SEC via EDGAR on August 1, 1995.

   
           5   (f)  Supplement to Investment Advisory Agreement between
                    Registrant and Morgan Stanley Asset Management Inc. (adding
                    the Emerging Markets, High Yield and International Small Cap
                    Portfolios) is incorporated by reference to Post-Effective
                    Amendment No. 25 to the Registrant's Registration Statement
                    on Form N-1A (File Nos. 33-23166 and 811-5624), as filed
                    with the SEC via EDGAR on August 1, 1995.
    

   
           5   (g)  Supplement to Investment Advisory Agreement between
                    Registrant and Morgan Stanley Asset Management Inc. (adding
                    the Small Cap Value Equity Portfolio) is incorporated by
                    reference to Post-Effective Amendment No. 25 to the
                    Registrant's Registration Statement on Form N-1A (File Nos.
                    33-23166 and 811-5624), as filed with the SEC via EDGAR on
                    August 1, 1995.
    

   
           5   (h)  Supplement to Investment Advisory Agreement between
                    Registrant and Morgan Stanley Asset Management Inc. (adding
                    the Emerging Markets Debt, Mortgage-Backed Securities,
                    Municipal Bond and Japanese Equity Portfolios) is
                    incorporated by reference to Post-Effective Amendment No. 25
                    to the Registrant's Registration Statement on Form N-1A
                    (File Nos. 33-23166 and 811-5624), as filed with the SEC via
                    EDGAR on August 1, 1995.
    

   
           5   (i)  Sub-Advisory Agreement among Registrant, Morgan Stanley
                    Asset Management Inc. and Sun Valley Gold Company (with
                    respect to the Gold Portfolio) is incorporated by reference
                    to Post-Effective Amendment No. 25 to the Registrant's
                    Registration Statement on Form N-1A (File Nos. 33-23166 and
                    811-5624), as filed with the SEC via EDGAR on August 1,
                    1995.
    

   
           5   (j)  Supplement to Investment Advisory Agreement between
                    Registrant and Morgan Stanley Asset Management Inc. (adding
                    the China Growth Portfolio) is incorporated by reference to
                    Post-Effective Amendment No. 25 to the Registrant's
                    Registration Statement on Form N-1A (File Nos. 33-23166 and
                    811-5624), as filed with the SEC via EDGAR on August 1,
                    1995.
    

   
           5   (k)  Supplement to Investment Advisory Agreement between
                    Registrant and Morgan Stanley Asset Management Inc. (adding
                    the Latin American Portfolio) is incorporated by reference
                    to Post-Effective Amendment No. 25 to the Registrant's
                    Registration Statement on Form N-1A (File Nos. 33-23166 and
                    811-5624), as filed with the SEC via EDGAR on August 1,
                    1995.
    

   
           5   (l)  Withdrawn.
    

   
           5   (m)  Supplement to Investment Advisory Agreement between
                    Registrant and Morgan Stanley Asset Management Inc. (adding
                    the Aggressive Equity and U.S. Real Estate Portfolios) is
                    incorporated by reference to Post-Effective Amendment No. 25
                    to the Registrant's Registration Statement on Form N-1A
                    (File Nos. 33-23166 and 811-5624), as filed with the SEC via
                    EDGAR on August 1, 1995.
    
                                          2

<PAGE>

   
           5   (n)  Supplement to Investment Advisory Agreement between
                    Registrant and Morgan Stanley Asset Management Inc. (adding
                    the MicroCap Portfolio) is incorporated by reference to
                    Post-Effective Amendment No. 25 to the Registrant's
                    Registration Statement on Form N-1A (File Nos. 33-23166 and
                    811-5624), as filed with the SEC via EDGAR on August 1,
                    1995.
    

   
           5   (o)  Supplement to Investment Advisory Agreement between
                    Registrant and Morgan Stanley Asset Management Inc. (adding
                    the International Magnum Portfolio) is incorporated by
                    reference to Post-Effective Amendment No. 28 to the
                    Registrant's Registration Statement of Form N-1A (File Nos.
                    33-23166 and 811-5624), as filed with the SEC via EDGAR on
                    November 3, 1995.
    

   
           5   (p)  Supplement to Investment Advisory Agreement between
                    Registrant and Morgan Stanley Asset Management Inc. (adding
                    the Technology Portfolio), is  incorporated by reference to 
                    Post-Effective Amendment No. 33 to the Registrant's 
                    Registration Statement on Form N-1A (File Nos. 33-23166 and 
                    811-5624), as filed with the SEC via EDGAR on
                    February 28, 1997.
    

   
           6   (a)  Distribution Agreement between Registrant and Morgan Stanley
                    & Co. Incorporated is incorporated by reference to Post-
                    Effective Amendment No. 25 to the Registrant's Registration
                    Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
                    filed with the SEC via EDGAR on August 1, 1995.
    

   
           6   (b)  Supplement to Distribution Agreement between Registrant and
                    Morgan Stanley & Co. Incorporated is incorporated by
                    reference to Post-Effective Amendment No. 29 to the
                    Registrant's Registration Statement on Form N-1A (File Nos.
                    33-23166 and 811-5624), as filed with the SEC via EDGAR on
                    April 29, 1996.
    

   
           8   (a)  Mutual Fund Custody Agreement (Domestic Custody Agreement)
                    between Registrant and United States Trust Company of New
                    York dated March 10, 1994 is incorporated by reference to
                    Post-Effective Amendment No. 25 to the Registrant's
                    Registration Statement on Form N-1A (File Nos. 33-23166 and
                    811-5624), as filed with the SEC via EDGAR on August 1,
                    1995.
    

   
           8   (b)  Registrant's Custody Agreement (International), dated July
                    31, 1989, as amended is incorporated by reference to Post-
                    Effective Amendment No. 25 to the Registrant's Registration
                    Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
                    filed with the SEC via EDGAR on August 1, 1995.
    

   
           8   (c)  Amendment dated April 22, 1996 to Registrant's Custody
                    Agreement (International), dated July 31, 1989, is 
                    incorporated by reference to Post-Effective Amendment No. 
                    30 to the Registrant's Registration Statement on Form 
                    N-1A  (File Nos. 33-23166 and 811-5624), as filed with the
                    SEC via EDGAR on May 24, 1996.
    

   
           9   (a)  Administration Agreement between Registrant and Morgan
                    Stanley Asset Management Inc. (the "MSAM Administration
                    Agreement") is incorporated by reference to Post-Effective
                    Amendment No. 25 to the Registrant's Registration Statement
                    on Form N-1A (File Nos. 33-23166 and 811-5624), as filed
                    with the SEC via EDGAR on August 1, 1995.
    

   
          9    (b)  U.S. Trust Administration Agreement is incorporated by
                    reference to Post-Effective Amendment No. 25 to the
                    Registrant's Registration Statement on Form N-1A (File Nos.
                    33-23166 and 811-5624), as filed
    

                                          3

<PAGE>

                    with the SEC via EDGAR on August 1, 1995.

   
          10        Opinion of Counsel is incorporated by reference to Post-
                    Effective Amendment No. 25 to the Registrant's Registration
                    Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
                    filed with the SEC via EDGAR on August 1, 1995.
    

   
EX-99.B   11        Consent of Independent Accountants is filed herewith.
    

   
          13        Purchase Agreement is incorporated by reference to Post-
                    Effective Amendment No. 25 to the Registrant's Registration
                    Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
                    filed with the SEC via EDGAR on August 1, 1995.
    

   
          15        Plan of Distribution Pursuant to Rule 12b-1 for
                    Class B Shares (the "Class B Plan") of the Active Country
                    Allocation Portfolio is incorporated by reference to 
                    Post-Effective Amendment No. 33 to the Registrant's 
                    Registration Statement on Form N-1A (File Nos. 33-23166 and 
                    811-5624), as filed with the SEC via EDGAR on 
                    February 28, 1997. The following Class B Plans have been
                    omitted because they are substantially identical to the 
                    one incorporated by reference herein.  The omitted Class B
                    Plans differ from the Class B Plan incorporated by reference
                    herein only with respect to the portfolio to which the 
                    Class B Plan relates:  Fixed Income, Global Fixed Income,
                    Municipal Bond, Mortgage-Backed Securities, High Yield,
                    Money Market, Municipal Money Market, Small Cap Value 
                    Equity, Value Equity, Balanced, Gold, Global Equity,
                    International Equity, International Small Cap, Asian 
                    Equity, European Equity, Japanese Equity, Latin American,
                    Emerging Markets, Emerging Markets Debt, China Growth, 
                    Equity Growth, Emerging Growth, MicroCap, Aggressive Equity,
                    U.S. Real Estate, International Magnum and Technology
                    Portfolios.
    

   
          16        Schedule of Computation of Performance Information is
                    incorporated by reference to Post-Effective Amendment No. 25
                    to the Registrant's Registration Statement on Form N-1A
                    (File Nos. 33-23166 and 811-5624), as filed with the SEC via
                    EDGAR on August 1, 1995.
    

   
          19        Registrant's Rule 18f-3 Multiple Class Plan is incorporated
                    by reference to Post-Effective Amendment No. 33 to the 
                    Registrant's Registration Statement on Form N-1A 
                    (File Nos. 33-23166 and 811-5624), as filed with the 
                    SEC via EDGAR on February 28, 1997.
    

   
          24        Powers of Attorney are incorporated by reference to Post-
                    Effective Amendment No. 25 to the Registrant's Registration
                    Statement on Form N-1A (File Nos. 33-23166 and 811-5624), as
                    filed with the SEC via EDGAR on August 1, 1995.

EX-99.b   27        Finanical data schedules for the fiscal year ended 
                    December 31, 1996 for Registrant's portfolios in 
                    operation during such period (See Item 24(a)), 
                    are filed herewith.


    

                                          4


<PAGE>








CONSENT OF INDEPENDENT ACCOUNTANTS


We hereby consent to the incorporation by reference in the Prospectuses and 
Statements of Additional Information constituting parts of this 
Post-Effective Amendment No. 34 to the registration statement on Form N-1A 
(the "Registration Statement") of our report dated February 10, 1997, 
relating to the financial statements and financial highlights appearing in 
the December 31, 1996 Annual Report to Shareholders of Morgan Stanley 
Institutional Fund, Inc., which are also incorporated by reference into the 
Registration Statement. We also consent to the references to us under the 
headings "Financial Highlights" and "General Information -- Independent 
Accountants" in the International Magnum Portfolio Prospectus; U.S. Real 
Estate Portfolio Prospectus; Equity Growth Portfolio, Emerging Growth 
Portfolio, MicroCap Portfolio, Aggressive Equity Portfolio Prospectus; 
Emerging Markets Portfolio, Emerging Markets Debt Portfolio Prospectus; Gold 
Portfolio Prospectus; Active Country Allocation Portfolio Prospectus; Small 
Cap Value Equity Portfolio, Value Equity Portfolio, Balanced Portfolio, 
Global Fixed Income Portfolio, High Yield Portfolio Prospectus; Fixed Income 
Portfolio, Municipal Bond Portfolio, Mortgage-Backed Securities Portfolio, 
Money Market Portfolio, Municipal Money Market Portfolio Prospectus; Global 
Equity Portfolio, International Equity Portfolio, International Small Cap 
Portfolio, Asian Equity Portfolio, European Equity Portfolio, Japanese Equity 
Portfolio, Latin American Portfolio Prospectus; and Technology Portfolio 
Prospectus and under the heading "Financial Statements" in the Statement of 
Additional Information (for all portfolios constituting Morgan Stanley 
Institutional Fund, Inc., excluding Technology Portfolio) and in the 
Statement of Additional Information for Technology Portfolio.



/s/ Price Waterhouse LLP


PRICE WATERHOUSE LLP
1177 Avenue of the Americas
New York, New York 10036
April 28, 1997


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   <NAME> ASIAN EQUITY PORTFOLIO, CLASS A
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</TABLE>

<TABLE> <S> <C>

<PAGE>
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   <NUMBER> 122
   <NAME> ASIAN EQUITY PORTFOLIO, CLASS B
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
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<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
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   <NAME> BALANCED PORTFOLIO, CLASS A
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 062
   <NAME> BALANCED PORTFOLIO, CLASS B
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
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   <NAME> EMERGING GROWTH PORTFOLIO, CLASS A
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
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   <NAME> EMERGING GROWTH PORTFOLIO, CLASS B
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
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   <NUMBER> 131
   <NAME> EMERGING MARKETS PORTFOLIO, CLASS A
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
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<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 132
   <NAME> EMERGING MARKETS PORTFOLIO, CLASS B
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<S>                             <C>
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<EXPENSE-RATIO>                                   1.99
<AVG-DEBT-OUTSTANDING>                               0
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 211
   <NAME> EMERGING MARKETS DEBT PORTFOLIO, CLASS A
   <MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                  12-MOS
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<EXPENSE-RATIO>                                   2.70
<AVG-DEBT-OUTSTANDING>                               0
<AVG-DEBT-PER-SHARE>                                 0
        


</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 212
   <NAME> EMERGING MARKETS DEBT PORTFOLIO, CLASS B
   <MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   OTHER
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<NUMBER-OF-SHARES-REDEEMED>                      (103)
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<PER-SHARE-NAV-END>                               7.53
<EXPENSE-RATIO>                                   2.81
<AVG-DEBT-OUTSTANDING>                               0
<AVG-DEBT-PER-SHARE>                                 0
        


</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 111
   <NAME> EQUITY GROWTH PORTFOLIO, CLASS A
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
<FISCAL-YEAR-END>                          DEC-31-1996
<PERIOD-START>                             JAN-01-1996
<PERIOD-END>                               DEC-31-1996
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<EXPENSE-RATIO>                                   0.80
<AVG-DEBT-OUTSTANDING>                               0
<AVG-DEBT-PER-SHARE>                                 0
        


</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 112
   <NAME> EQUITY GROWTH PORTFOLIO, CLASS B
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   OTHER
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<EXPENSE-RATIO>                                   1.05
<AVG-DEBT-OUTSTANDING>                               0
<AVG-DEBT-PER-SHARE>                                 0
        


</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 091
   <NAME> EUROPEAN EQUITY PORTFOLIO, CLASS A
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
<FISCAL-YEAR-END>                          DEC-31-1996
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<PERIOD-END>                               DEC-31-1996
<INVESTMENTS-AT-COST>                          152,077
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<PER-SHARE-NAV-END>                              16.70
<EXPENSE-RATIO>                                   1.00
<AVG-DEBT-OUTSTANDING>                               0
<AVG-DEBT-PER-SHARE>                                 0
        


</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC. 
<SERIES>
   <NUMBER> 092
   <NAME> EUROPEAN EQUITY PORTFOLIO, CLASS B
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   OTHER
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<EXPENSE-RATIO>                                   1.25
<AVG-DEBT-OUTSTANDING>                               0
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 071
   <NAME> FIXED INCOME PORTFOLIO, CLASS A
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                  12-MOS
<FISCAL-YEAR-END>                          DEC-31-1996
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<PER-SHARE-NAV-END>                              10.58
<EXPENSE-RATIO>                                   0.45
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<AVG-DEBT-PER-SHARE>                                 0
        


</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 072
   <NAME> FIXED INCOME PORTFOLIO, CLASS B
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   OTHER
<FISCAL-YEAR-END>                          DEC-31-1996
<PERIOD-START>                             JAN-02-1996
<PERIOD-END>                               DEC-31-1996
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 081
   <NAME> GLOBAL EQUITY PORTFOLIO, CLASS A
<MULTIPLIER> 1,000
       
<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 082
   <NAME> GLOBAL EQUITY PORTFOLIO, CLASS B
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 101
   <NAME> GLOBAL FIXED INCOME PORTFOLIO, CLASS A
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                  12-MOS
<FISCAL-YEAR-END>                          DEC-31-1996
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 102
   <NAME> GLOBAL FIXED INCOME PORTFOLIO, CLASS B
<MULTIPLIER> 1,000
       
<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 191
   <NAME> GOLD PORTFOLIO, CLASS A
<MULTIPLIER> 1,000
       
<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 192
   <NAME> GOLD PORTFOLIO, CLASS B
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 161
   <NAME> HIGH YIELD PORTFOLIO, CLASS A
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
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<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 162
   <NAME> HIGH YIELD PORTFOLIO, CLASS B
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
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<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
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   <NAME> INTERNATIONAL EQUITY PORTFOLIO, CLASS A
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 042
   <NAME> INTERNATIONAL EQUITY PORTFOLIO, CLASS B
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<S>                             <C>
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</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 281
   <NAME> INTERNATIONAL MAGNUM PORTFOLIO, CLASS A
<MULTIPLIER> 1,000
       
<S>                             <C>
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</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 282
   <NAME> INTERNATIONAL MAGNUM PORTFOLIO, CLASS B
<MULTIPLIER> 1,000
       
<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 15
   <NAME> INTERNATIONAL SMALL CAP PORTFOLIO
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 201
   <NAME> JAPANESE EQUITY PORTFOLIO, CLASS A
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 202
   <NAME> JAPANESE EQUITY PORTFOLIO, CLASS B
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
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<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
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   <NAME> LATIN AMERICAN PORTFOLIO, CLASS A
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</TABLE>

<TABLE> <S> <C>

<PAGE>
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<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
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   <NAME> LATIN AMERICAN PORTFOLIO, CLASS B
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
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<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
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   <NUMBER> 1
   <NAME> MONEY MARKET PORTFOLIO
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
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<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 232
   <NAME> MUNICIPAL BOND PORTFOLIO, CLASS B
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 231
   <NAME> MUNICIPAL BOND PORTFOLIO, CLASS A
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
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   <NAME> MUNICIPAL MONEY MARKET PORTFOLIO
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
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<SERIES>
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   <NAME> SMALL CAP VALUE EQUITY PORTFOLIO, CLASS A
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 172
   <NAME> SMALL CAP VALUE EQUITY PORTFOLIO, CLASS B
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 030
   <NAME> THE TECHNOLOGY PORTFOLIO, CLASS A
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 031
   <NAME> THE TECHNOLOGY PORTFOLIO, CLASS B
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<S>                             <C>
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</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
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   <NUMBER> 261
   <NAME> U.S. REAL ESTATE PORTFOLIO, CLASS A
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<S>                             <C>
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</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 262
   <NAME> U.S. REAL ESTATE PORTFOLIO, CLASS B
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 051
   <NAME> VALUE EQUITY PORTFOLIO, CLASS A
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<S>                             <C>
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</TABLE>

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 6
<CIK> 0000836487
<NAME> MORGAN STANLEY INSTITUTIONAL FUND, INC.
<SERIES>
   <NUMBER> 052
   <NAME> VALUE EQUITY PORTFOLIO, CLASS B
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<S>                             <C>
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</TABLE>


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