ENTROPIN INC
PRE 14A, 2000-04-26
MANAGEMENT SERVICES
Previous: SEPARATE ACCOUNT B OF GOLDEN AMERICAN LIFE INSURANCE CO, 485BPOS, 2000-04-26
Next: SPARTA FOODS INC, DEFM14A, 2000-04-26



            UNITED STATES SECURITIES AND EXCHANGE COMMISSION
                         WASHINGTON, D.C. 20549

                              SCHEDULE 14A

               Proxy Statement Pursuant to Section 14(a)
                 of the Securities Exchange Act of 1934


Filed by the Registrant [X ]

Filed by a Party other than the Registrant [_]

Check the appropriate box:

[X] Preliminary Proxy Statement

[_]CONFIDENTIAL, FOR USE OF THE COMMISSION ONLY (AS PERMITTED BY RULE
14A-6(E)(2))

[ ] Definitive Proxy Statement

[_] Definitive Additional Materials

[_] Soliciting Material Pursuant to (S) 240.14a-11(c) or (S) 240.14a-12

                             ENTROPIN, INC.
        --------------------------------------------------------
            (Name of Registrant as Specified In Its Charter)

        ---------------------------------------------------------
(Name of Person(s) Filing Proxy Statement, if other than the Registrant)

 Payment of Filing Fee (Check the appropriate box):

[ ] No fee required.

[_] Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.

     (1) Title of each class of securities to which transaction applies:

     -----------------------------------------------------------------

                                    1
<PAGE>
     (2) Aggregate number of securities to which transaction applies:

     -----------------------------------------------------------------

     (3) Per unit price or other underlying value of transaction computed
pursuant to Exchange Act Rule 0-11 (set forth the amount on which the
filing fee is calculated and state how it was determined):

     -----------------------------------------------------------------

     (4) Proposed maximum aggregate value of transaction:

     -----------------------------------------------------------------

     (5) Total fee paid:

     -----------------------------------------------------------------

[_] Fee paid previously with preliminary materials.

[_] Check box if any part of the fee is offset as provided by Exchange Act
Rule 0-11(a)(2) and identify the filing for which the offsetting fee was
paid previously. Identify the previous filing by registration statement
number, or the Form or Schedule and the date of its filing.

     (1) Amount Previously Paid:

     -----------------------------------------------------------------

     (2) Form, Schedule or Registration Statement No.:

     -----------------------------------------------------------------

     (3) Filing Party:

     -----------------------------------------------------------------

     (4) Date Filed:

     -----------------------------------------------------------------

Notes:



                                    2
<PAGE>
                             ENTROPIN, INC.
                           45926 Oasis Street
                             Indio, CA 92201


                             May [   ], 2000


Dear Shareholder:

     You are cordially invited to attend the Annual Meeting of Shareholders
of Entropin, Inc. (the "Company") on June 14, 2000 at 8:00 A.M. Mountain
Daylight Time.  The meeting will be held at The Westin Tabor Center, 1672
Lawrence Street, Denver, Co 80202.

     The accompanying Notice of Meeting and Proxy Statement describe the
matters to be considered and voted upon at the Meeting.  In addition to
consideration of these matters, there will be a report to the Shareholders
on the affairs of the Company, and Shareholders will have an opportunity to
discuss matters of interest regarding the Company.

     It is important that your shares be represented, whether or not you
plan to attend the Meeting personally.  To ensure that your vote will be
received and counted, please promptly complete, date and return your proxy
in the enclosed return envelope, whether or not you plan to attend the
meeting in person.

     We look forward to seeing you at the Annual Meeting.

                              Sincerely,


                              ______________________________________
                              Higgins D. Bailey
                              Chairman of the Board









                                    3
<PAGE>
                             ENTROPIN, INC.
                           45926 Oasis Street
                             Indio, CA 92201
___________________________________________________________________________
                NOTICE OF ANNUAL MEETING OF SHAREHOLDERS
                       To be held on June 14, 2000
___________________________________________________________________________
                                                            May [ ], 2000
TO THE SHAREHOLDERS OF ENTROPIN, INC.:

     NOTICE is hereby given that the Annual Meeting of Shareholders of
Entropin, Inc., a Colorado corporation (the "Company"), will be held at The
Westin Tabor Center, 1672 Lawrence Street, Denver, Co 80202, on Wednesday,
June 14, 2000, at 8:00 A.M. Mountain Daylight Time, to consider and take
action on the following matters:

     1.   A proposal to amend the Articles of Incorporation to modify the
          lengths of the terms of the directors of the Company;

     2.   To elect seven directors to such terms as will be required by the
          Articles of Incorporation as may be amended by proposal 1, above;

     3.   A proposal to ratify the 1998 Compensatory Stock Plan and an
          amendment increasing the maximum aggregate number of shares
          reserved for issuance thereunder to 500,000 shares of Common
          Stock;

     4.   To ratify the selection of Causey Demgen & Moore, Inc. as
          independent auditors of the Company for the year ending December 31,
          2000; and

     5.   To transact such other business as may properly come before the
          meeting or any adjournment thereof.

     The statement of the proposals of the Board of Directors set forth
above is intended only as a summary, and is qualified in its entirety by
the information relating to the proposals set forth in the accompanying
Proxy Statement.

     The Board of Directors has fixed the close of business on May 9, 2000,
as the record date for the determination of Shareholders entitled to notice
of the Annual Meeting and entitled to vote at this Annual Meeting and at
any continuation, postponement or adjournment thereof.

                                   By Order of the Board of Directors


                                   Higgins D. Bailey, Chairman of the Board

                                    4
<PAGE>
                             ENTROPIN, INC.
                           45926 Oasis Street
                             Indio, CA 92201
___________________________________________________________________________
                             PROXY STATEMENT
___________________________________________________________________________
                             TABLE OF CONTENTS

Schedule 14(a) . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
Shareholder Letter . . . . . . . . . . . . . . . . . . . . . . . . . 3
Notice of Annual Meeting of Shareholders . . . . . . . . . . . . . . 4
Proxy Statement. . . . . . . . . . . . . . . . . . . . . . . . . . . 5
Information Concerning Solicitation and Voting . . . . . . . . . . . 5
     General . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
     Revocability of Proxy . . . . . . . . . . . . . . . . . . . . . 5
     Solicitation. . . . . . . . . . . . . . . . . . . . . . . . . . 6
     Voting Securities and Principal Shareholders. . . . . . . . . . 6
Proposal 1:   PROPOSAL TO AMEND THE ARTICLES OF INCORPORATION
              TO MODIFY THE LENGTH OF TERMS FOR THE DIRECTORS
              OF THE COMPANY . . . . . . . . . . . . . . . . . . . . 8
Proposal 2:   ELECTION OF DIRECTORS. . . . . . . . . . . . . . . . .10
     Directors and Executive Officers. . . . . . . . . . . . . . . .13
     Summary Compensation Table. . . . . . . . . . . . . . . . . . .14
     Related Party and Other Material Transactions . . . . . . . . .17
     Section 16(a) Beneficial Ownership Reporting Compliance . . . .18
Proposal 3:   RATIFICATION OF THE 1998 COMPENSATORY STOCK
              PLAN AND AN AMENDMENT INCREASING THE MAXIMUM
              AGGREGATE NUMBER OF SHARES RESERVED FOR
              ISSUANCE THEREUNDER TO 500,000 SHARES
              OF COMMON STOCK. . . . . . . . . . . . . . . . . . . .18
Proposal 4:   RATIFICATION OF SELECTION OF
              INDEPENDENT AUDITORS . . . . . . . . . . . . . . . . .20
Financial Statements and Information . . . . . . . . . . . . . . . .20
Shareholder Proposals to be Presented at the Next Annual Meeting . .20
Transaction of Other Business. . . . . . . . . . . . . . . . . . . .21

Exhibits
     Audit Committee Charter
     1998 Compensatory Stock Plan
     10-KSB




                                    5
<PAGE>
             INFORMATION CONCERNING SOLICITATION AND VOTING

                               GENERAL

     The enclosed proxy is solicited on behalf of the Board of Directors
(the "Board") of Entropin, Inc., a Colorado corporation (the "Company" or
"Entropin"), for use at the Annual Meeting of Shareholders to be held on
Wednesday, June 14, 2000, at 8:00 A.M., Mountain Daylight Time (the "Annual
Meeting"), or at any continuation, postponement or adjournment thereof, for
the purposes set forth herein and in the accompanying Notice of Annual
Meeting.  The Annual Meeting will be held at The Westin Tabor Center, 1672
Lawrence Street, Denver, Co 80202.  The Proxy and Proxy statement will be
mailed to Shareholders on or about [MAILING DATE].

                          REVOCABILITY OF PROXY

     If the enclosed Proxy is executed and returned, it will be voted on
the proposals as indicated by the shareholder.  The Proxy may be revoked by
the shareholder at any time prior to its use by notice in writing to the
Secretary of the Company, by executing a later dated proxy and delivering
it to the Company prior to the meeting or by voting in person at the meeting.

                              SOLICITATION

     The cost of preparing, assembling and mailing the Notice of Meeting,
Proxy Statement and Proxy (the "Proxy Materials"), miscellaneous costs with
respect to the Proxy Materials and solicitation of the Proxies will be paid
by the Company.  The Company also may use the services of its directors,
officers and employees to solicit Proxies, personally or by telephone and
telegraph, but at no additional salary or compensation.  The Company
intends to request banks, brokerage houses and other custodians, nominees
and fiduciaries to forward copies of the Proxy Materials to those persons
for whom they hold such shares and request authority for the execution of
the Proxies.  The Company will reimburse them for the reasonable out-of-
pocket expenses incurred by them in so doing.

              VOTING SECURITIES AND PRINCIPAL SHAREHOLDERS

     Shareholders of record at the close of business on May 9, 2000, will
be entitled to vote on all matters.  On the record date the Company had
9,382,280 shares of Common Stock ($.001 par value) (the "Common Stock")
outstanding.  The holders of the Common Stock are entitled to one vote per
share.  The Company has no classes of voting securities outstanding other
than its Common Stock.  One-third of the issued and outstanding shares of
all classes of voting securities entitled to vote, represented in person or
by proxy, constitutes a quorum at any Shareholders' meeting.  Broker non-
votes and abstentions will be counted for purposes of determining a quorum;
however, they will not be counted as votes cast.  Therefore, such votes
will not have the effect of a negative vote or a vote against any proposal.

                                    6
<PAGE>
     The following table sets forth certain information regarding the
holdings of Common Stock (1) by each person who, as of May 1, 2000 holds of
record or is known by us to hold beneficially or of record, more than 5% of
our Common Stock, (2) by each executive officer and director, and (3) by
all officers and directors as a group.  The address of each person is our
address at 45926 Oasis Street, Indio, California 92201.  The beneficial
ownership is determined in accordance with the rules of the Securities and
Exchange Commission and generally includes voting or investment power with
respect to securities.  Shares of Common Stock issuable on exercise of
currently exercisable or convertible securities or securities exercisable
or convertible within 60 days after the record date are deemed beneficially
owned and outstanding for computing the percentage owned by the person
holding such securities, but are not considered outstanding for computing
the percentage of any other person.


                                          Number of        Percentage of
                                           Shares             Shares
                                        Beneficially       Beneficially
Name of Beneficial Owners                  Owned              Owned
- -------------------------                  -----              -----


Thomas G. Tachovsky                            -0- (1)          *

Higgins D. Bailey                        1,544,926 (2)        16.0

Thomas T. Anderson                       1,404,093 (3)        15.0

Caroline T. Somers                         822,793             8.8

James E. Wynn                              492,751 (4)         5.2

Daniel L. Azarnoff                          87,777 (5)         0.9

Donald Hunter                              566,333 (6)         5.8

Wilson Benjamin                             90,833 (7)         1.0

Joseph R. Ianelli                            8,333 (8)          *

All directors and executive
officers as a group (7 persons)          2,790,953            27.3
___________________
*    Less than 1/10 of 1%.
(1)  Does not include up to 400,000 shares issuable upon exercise of stock
     options, none of which are vested.
(2)  Includes 1,279,093 shares owned in joint tenancy with Shirley A.
     Bailey, the spouse of Dr. Bailey, and 265,833 shares that are issuable
     upon exercise of stock options.
(3)  Held of record by Dr. Bailey as security for a loan made by Dr. Bailey
     to Mr. Anderson.
(4)  Represents 401,085 shares which are owned in joint tenancy with Joyce
     Wynn, the spouse of Dr. Wynn, 45,000 shares held solely by Joyce Wynn,
     and 46,666 shares that are issuable upon exercise of stock options.
(5)  Represents the following shares issuable upon exercise of stock
     options: options to purchase 43,333 shares granted to Dr. Azarnoff;
     and, options to purchase an aggregate of 133,332 shares granted to
     Western Center for Clinical Studies, which are fully  vested, of which
     44,444 shares are attributable to Dr. Azarnoff who owns 1/3 of the
     voting shares.
(6)  Of these shares, 35,500 shares are held in the name of Deloras Decker
     Hunter, Trustee of the Deloras Decker Hunter Generation Skipping
     Trust.  Deloras Decker Hunter is the spouse of Mr. Hunter and Mr.
     Hunter is deemed to have voting control over these 35,500 shares.  In
     addition, includes 450,833 shares that are issuable

                                    7
<PAGE>
     upon exercise of stock options.
(7)  Includes 28,333 shares that are issuable upon exercise of stock
     options.
(8)  Represents shares issuable upon exercise of stock options.


                               PROPOSAL 1
             PROPOSAL TO AMEND THE ARTICLES OF INCORPORATION
     TO MODIFY THE LENGTH OF TERMS FOR THE DIRECTORS OF THE COMPANY


     The Board of Directors has voted to authorize an amendment to Article
IV of the Company's Articles of Incorporation and to recommend such
proposed amendment to the Shareholders for adoption.   Although this
proposal may have the effect of discouraging a holder of a large block of
the Company's securities from attempting a merger, tender offer, proxy
contest, or other assumption of control with or for the Company or the
removal of incumbent management, the Company is not aware of any proposed
attempt to take over the Company or of any attempt to acquire a large block
of the Common Stock, and the proposed amendment to the Company's Articles
of Incorporation is not in response to any specific effort to do so.  The
purpose of Proposal 1 is to enhance continuity and stability in the
composition of the Company's Board of Directors and in the policies
formulated by the Board. If this proposal is adopted by the Shareholders,
Article IV of  the Articles of Incorporation will be amended to add
following paragraph:

          Classification of Directors. The directors shall be divided into
     three classes, designated Class I, Class II and Class III. Each class
     shall consist, as nearly as possible, of one-third of the total number
     of directors constituting the entire Board of Directors. The term of
     the initial Class I directors shall  terminate on the date of the 2001
     annual meeting of Shareholders; the term of the initial Class II
     directors shall terminate on the date of the 2002 annual meeting of
     Shareholders; and the term of the initial Class III directors shall
     terminate on the date of the 2003 annual meeting of Shareholders. At
     each meeting of Shareholders beginning in 2001, successors to the
     class of directors whose term expires at that annual meeting shall be
     elected for a three-year term. If the number of directors is changed,
     any increase or decrease in directorships shall be apportioned among
     the classes so as to maintain the number of directors in each class as
     nearly equal as possible, and any additional directors of any class
     elected to fill a vacancy resulting from an increase in such class
     shall hold office until the next election of directors of such class
     by the Shareholders, but in no case will a decrease in the number of
     directors shorten the term of any incumbent director. Directors shall
     hold office until the annual meeting for the year in which their terms
     expire and until their successors shall be elected and shall qualify,
     subject, however, to prior death, resignation, retirement,
     disqualification or removal from office. Any vacancy on the Board of
     Directors, howsoever resulting, may be filled by the affirmative vote
     of a majority of the remaining directors then in office, even if less
     than a quorum. Any director elected to fill a vacancy shall hold office
     until the next election of directors of such class by the Shareholders.

                                    8
<PAGE>
     This proposal provides for three classes of directors, each consisting
as nearly as possible of one-third of the Board and for one-third of the
Board to be elected each year.  However, members of all three classes would
be elected initially at the Annual Meeting. If this proposal is approved
and the slate of seven directors proposed for election at the Annual
Meeting are elected, they would be elected in three separate classes as
follows: two "Class I Directors" would be elected for a term expiring at
the 2001 Annual Meeting; three "Class II Directors" would be elected for a
term expiring at the 2002 Annual Meeting; and two "Class III Directors"
would be elected for a term expiring at the 2003 Annual Meeting. At each
annual meeting after the Meeting, only directors of the class whose term is
expiring would be voted upon, and upon election each such director would
serve a three-year term.  Currently, the Company's Articles of
Incorporation provide that the number of directors of the Company shall be
fixed by the by-laws, and the by-laws provide that the number shall never
be less than three or more than seven.  Subject to Colorado law, this
proposal expressly delegates to incumbent directors sole power to fill
vacancies whether occurring by an increase in the number of directors or
otherwise. A director elected to fill a vacancy would hold office for the
unexpired portion of the term of the director who was being replaced. A
director elected to fill a newly created directorship would hold office
until the next election for the class to which that director was elected.
If the size of the Board is increased, the additional directors would be
apportioned among the three classes of directors to keep all such classes
as nearly equal as possible. The Board of Directors believes that the
adoption of this proposal is advantageous to the Company and its
Shareholders for a number of reasons.  Providing that directors will serve
three year terms rather than one year terms, will enhance continuity and
stability in the composition of the Company's Board of Directors and in the
policies formulated by the Board.  Public companies are potentially subject
to attempts by various individuals and entities to acquire significant
minority positions in the company with the intent either of obtaining
actual control of the company by electing their own slate of directors, or
of achieving some other goal, such as the repurchase of their shares by the
company at a premium.  Public companies also are potentially subject to
inadequately priced or coercive bids for control through majority share
ownership. These prospective acquirers may be in a position to elect a
company's entire board of directors through proxy contest or otherwise,
even though they do not own a majority of the company's then outstanding
shares at the time.  If this proposal is approved, a majority of the
Company's directors could not be removed by such persons until two annual
meetings of Shareholders have occurred, unless such removal was for cause
and the requisite vote was obtained.  By providing this additional time to
the Board of Directors and eliminating the possibility of rapid removal of
the Board, the directors of the Company will have the necessary time to
most effectively satisfy their responsibility to the Company's Shareholders
to evaluate any proposal and to assess and develop alternatives without the
pressure created by the threat of imminent removal.  The Board believes that
this will permit it to more effectively represent the interests of all
Shareholders, including responding to demands or actions by any shareholder
or group.  This proposal may discourage potential purchasers because its
provisions would operate to delay the purchaser's ability to obtain control
of the Board of Directors, since it will generally take a purchaser two
annual meetings of Shareholders to elect a majority of the Board.  The
Board has no knowledge of any present effort to gain control of the Company
or to organize a proxy contest.  However, the Board believes that adopting
this proposal  is prudent, advantageous and in the best interests of
Shareholders because it will give the Board more time to fulfill its
responsibilities to
                                    9
<PAGE>
Shareholders and, it will provide greater assurance of continuity and
stability in the composition and policies of the Board of Directors. The
Board also believes such advantages outweigh any disadvantage relating to
discouraging potential acquirers from attempting to obtain control of the
Company.  Approval of this proposal  requires an affirmative vote of holders
of a majority of the outstanding shares of the Company's Common Stock
entitled to vote in person or by proxy at the Annual Meeting.

     THE BOARD OF DIRECTORS BELIEVES THAT PROPOSAL 1 IS IN THE BEST
INTERESTS OF THE COMPANY AND ITS SHAREHOLDERS AND RECOMMENDS A VOTE FOR
APPROVAL OF PROPOSAL 1.

     It is the intention of the persons named in the accompanying form of
Proxy to vote the shares represented thereby in favor of such ratification
unless otherwise instructed in such Proxy.


                               PROPOSAL 2
                          ELECTION OF DIRECTORS

     Seven directors will be elected at the Annual Meeting. If the
Shareholders approve Proposal 1, the Board of Directors will be divided
into three classes with staggered terms of office. The initial
classification of the Board will be as follows: the Class I directors,
Daniel L. Azarnoff, M.D. and James E. Wynn, Ph.D., will serve until date of
the 2001 Annual Meeting of Shareholders; the Class II directors, Wilson
Benjamin, Joseph Ianelli and Donald Hunter, will serve until the date of
the 2002 Annual Meeting of Shareholders; and the Class III directors,
Higgins D. Bailey, Ed.D. and Thomas G. Tachovsky, Ph.D., will serve until
the date of the 2003 Annual Meeting of Shareholders. At each Annual Meeting
after 2000, directors will be elected to succeed those directors whose
terms then expire, and each person so elected will serve for a three-year
term. If Proposal 1 is not approved, directors elected at the Annual
Meeting will serve until the date of the 2001 Annual Meeting of
Shareholders and until their respective successors are duly elected and
shall have qualified.

     Directors are elected by a majority of the votes present in person or
represented by proxy and entitled to vote at the Annual Meeting.
Shareholders do not have the right to cumulate their votes in the election
of directors.  If, prior to the Annual Meeting, any nominee should become
unavailable for election, an event which currently is not anticipated by the
Board, the proxies will be voted for the election of such substitute nominee
or nominees as the Board of Directors may propose.  Each person nominated for
election has agreed to serve if elected and management has no reason to
believe that any nominee will be unable to serve.

     Set forth below is biographical information for each person nominated.

     DANIEL L. AZARNOFF, M.D. joined us as a director in February 1998 and
acted as our President on a part-time basis until April 1998.  Since 1988,
Dr. Azarnoff has been President of D. L. Azarnoff

                                    10
<PAGE>
Associates, a company engaged in consulting for various pharmaceutical and
biotechnology companies including Sandoz, Orion Pharma, DeNovo, Inc., Cibus
Pharmaceutical and Cellegy Pharmaceuticals, Inc.   Since August 1998, Dr.
Azarnoff has held a clinical faculty position at Stanford University
Medical School.  Prior to the time, he held faculty positions at the
University of Kansas Medical School, Northwestern University Medical
School, the University of Chicago Medical School and St. Louis University
School of Medicine.  Dr. Azarnoff is a director of Amerimmune, Inc., a
publicly held  pharmaceutical drug and development company and a director
of Western Center for Clinical Studies, Inc.  Since June 1999, he has
served as Senior Vice President, Medical/Regulatory Affairs for Cellegy
Pharmaceutical, Inc.  Dr. Azarnoff  received a B.S. degree in biology and
a M.S. degree in zoology from Rutgers University and a M.D. degree from the
University of Kansas Medical School.

     HIGGINS D. BAILEY, Ed.D. joined us as an officer and director in July
1992 and is currently our Chairman of the Board.  From July 1995 to
December 1996, Dr. Bailey was President and Chief Executive Officer for the
Pharmaceutical Educational and Development Foundation at the Medical
University of South Carolina, Charleston, South Carolina, which formulates
and manufactures pharmaceutical products.  Since 1991, he has served as the
business manager for Thomas T. Anderson Law Firm, Indio, California. Thomas
T. Anderson is one of our principal Shareholders.  Dr. Bailey received a
B.A. degree in biology from Eastern Washington University, a M.S. degree in
program planning and personnel and a Ed.D. degree in administration and
management from the University of California, Berkeley, California.

     WILSON BENJAMIN joined us as a director in February 2000.  Since 1992
he has been the President and Chief Executive Officer of Al Fawaris Co.
where he is responsible for Al Fawaris' investments and participation in
the management of certain of its portfolio companies.  Since 1992 he has
also served as the Chairman of the Board of Directors and Chief Executive
Officer of ATO Ram 2 Ltd. where he is responsible for managing ATO's
operations and its investments in public and private companies in the
United States, Europe and the Persian Gulf States.  Since 1999, he has been
the Chairman of the Board of Directors of Arab Commercial TV Co., a cable
television broadcasting company.  Mr. Benjamin received a B.A. in business
administration from Al Hikma University in Baghdad, Iraq.

     DONALD HUNTER joined us as a director and Secretary in February 1998.
In May 1999, he resigned as Secretary and was appointed as our Chief
Executive Officer and Treasurer.  He served as Chief Executive Officer
until November 1999 and Treasurer until January 2000.  Since 1994, Mr.
Hunter has served as a consultant to Entergy Corporation as well as other
concerns dealing with mergers and acquisitions and other business matters.
From 1991 to 1994, he was senior vice president of Entergy Corporation.  Mr.
Hunter received a B.S. degree in chemical engineering from Purdue University
and a M.S. degree in nuclear engineering from Iowa State University.

     JOSEPH R. IANELLI joined us as a director in February 2000.  Since
January 1999 he has been the President and Chief Executive Officer of
PharmaConnect, Inc. responsible for design and development of an internet
website for physicians.  Since January 1999 he has also been the

                                    11
<PAGE>
President and Chief Executive Officer of Renaissance Pharmaceuticals, Inc.  a
development stage company involved in drug delivery technologies.  From
1983 to January 1999 he served as the Senior Vice President of Business
Development for Astra U.S.A., Inc. where he was responsible for
acquisitions and licensing.  At Astra, he served on the Executive Committee
and was a member of the Management Advisory Board.  Mr. Ianelli received a
B.A. in Biology from Marist College, a M.A. in Biology from the State
University of New York and an M.B.A. from Iona College.

     THOMAS G. TACHOVSKY, Ph.D. joined us as a director, President and
Chief Executive Officer in November 1999.  Since June 1997 he has held a
series of interim senior management positions in development stage bio-
pharmaceutical companies including Redox Pharmaceuticals Corporation;
Novavax, Inc. and Paracelsian, Inc.  From June 1995 to November 1997, he
was a director and executive vice-president of Protyde Pharmaceuticals,
Inc.  From June 1991 to February 1998, he was general partner of MATCO &
Associates, a bio-pharmaceutical industry consulting firm for corporate
partnering, technology assessment and market valuation.  He has held
business development positions with Cytogen Corporation and Creative
Biomolecules and was a research and development manager with Johnson &
Johnson.  Dr. Tachovsky received a B.S. degree in biology from Gonzaga
University; a M.S. degree in management from Lesley College; and a Ph.D
degree in microbiology from the University of Rochester School of Medicine.

     JAMES E. WYNN, Ph.D. joined us as a director in February 1998.   Since
1977, Dr. Wynn has been a Professor and since September 1995, Assistant
Dean for Research at the Medical University of South Carolina.  Prior to
that time, he held various other positions at the University, including
Chairman of the Department of Pharmaceutical Sciences, College of Pharmacy
and principal investigator for the Drug Bioequivalence Evaluation Program.
 Dr. Wynn received a B.S. degree in pharmacy and a Ph.D. degree  in
medicinal chemistry from the Medical College of Virginia, Virginia
Commonwealth University, Richmond, Virginia.

     THE BOARD OF DIRECTORS BELIEVES THAT PROPOSAL 2 IS IN THE BEST
INTERESTS OF THE COMPANY AND ITS SHAREHOLDERS AND RECOMMENDS A VOTE FOR
DANIEL L. AZARNOFF, M.D. AND JAMES E. WYNN, PH.D. AS CLASS I DIRECTORS;
WILSON BENJAMIN, JOSEPH IANELLI AND DONALD HUNTER AS CLASS II DIRECTORS;
AND HIGGINS D. BAILEY, ED.D. AND THOMAS G. TACHOVSKY, PH.D. AS CLASS III
DIRECTORS, OR IN THE EVENT THAT PROPOSAL 1 IS NOT RATIFIED THE BOARD
RECOMMENDS A VOTE FOR DANIEL L. AZARNOFF, M.D., JAMES E. WYNN,
PH.D,.WILSON BENJAMIN, JOSEPH IANELLI, DONALD HUNTER, HIGGINS D. BAILEY,
ED.D. AND THOMAS G. TACHOVSKY, PH.D. TO SERVE AS DIRECTORS UNTIL THE 2001
ANNUAL MEETING.

     It is the intention of the persons named in the accompanying form of
Proxy to vote the shares represented thereby in favor of such directors
unless otherwise instructed in such Proxy.

                                    12
<PAGE>
                    DIRECTORS AND EXECUTIVE OFFICERS

The following table lists the names, ages and positions of our executive
officers and directors:


Name                        Age         Position
- ----                        ---         --------

Thomas G. Tachovsky         53     President, Chief Executive Officer and
                                   Director

Higgins D. Bailey           69     Chairman of the Board

Donald Hunter               66     Vice Chairman of the Board

Pat Kriss                   49     Secretary and Treasurer

Daniel L. Azarnoff          73     Director

James E. Wynn               57     Director

Wilson Benjamin             56     Director

Joseph R. Ianelli           61     Director

Wellington A. Ewen          60     Chief Financial Officer

     All members of the board of directors hold office until  the election
and qualification of their successors, or until death, resignation or
removal.  Messrs. Benjamin and Ianelli are independent directors.  Officers
serve at the discretion of the Board of Directors.  Wellington A. Ewen will
be resigning as of the date of the Annual Meeting and the Board of
Directors intends to appoint Pat Kriss as the new Chief Financial Officer
on that date.



                                   13
<PAGE>
                       SUMMARY COMPENSATION TABLE

     The following table provides certain summary information concerning
compensation paid to our Chief Executive Officers for the calendar years
1998 and 1999.  No officer was paid compensation for services in excess of
$100,000 per year for either year.

<TABLE>
<CAPTION>
                                                        Long Term
                                                   Compensation Awards
                                                   -------------------
                                                   Restricted
                              Annual Compensation    Stock    Options &      Other
Name and Position     Year   Salary($)    Bonus($)   Awards      SARs     Compensation
- -----------------     ----   ---------    --------   ------      ----     ------------

<S>                   <C>     <C>           <C>       <C>        <C>           <C>
Thomas G. Tachovsky,  1999    22,051        -0-       -0-        400,000       -0-
President and CEO
since 11/99(1)

Donald Hunter,        1999      -0-         -0-       -0-        217,500       -0-
CEO from 5/99 to 11/99(2)

Higgins D. Bailey     1999    95,833        -0-       -0-          -0-         -0-
Chairman and CEO from
1/98 until 9/98(3)

A. T. Tenenbaum       1999      -0-         -0-       -0-          -0-         -0-
CEO until 1/15/1998
</TABLE>
____________________

(1) Dr. Tachovsky received options to purchase 400,000 shares of our Common
Stock at $5.00 per share of which 100,000 shares are exercisable upon
completion of the first Phase III trial; 150,000 shares upon submission of
the NDA and 150,000 shares upon approval of the NDA.  The options expire
five years from the date they become exercisable.

(2) Mr. Hunter received options to purchase 217,500 shares of our Common
Stock at $4.00 per share, exercisable for five years from date of grant, as
compensation for services performed for us during the period of July 1,
1998 through November 30, 1999.  In August 1999, we also granted Mr. Hunter
options to purchase 120,000 shares of our Common Stock, exercisable at
$4.00 per share for a period of five years, as a bonus for services
rendered.

(3) Dr. Bailey's employment agreement terminated January 15, 1999.  During
1999, Dr. Bailey received options to purchase 97,500 shares of our Common
Stock at $4.00 per share, exercisable for five years from date of grant, as
compensation for services performed for us during the period from January 15,
1999 through September 1, 1999.  In August 1999, we also granted Dr. Bailey
options to purchase 120,000 shares of our Common Stock, exercisable at $4.00
per share for a period of five years, as a bonus for services rendered.

OPTIONS GRANTED TO DIRECTORS AND EXECUTIVE MANAGEMENT

     In 1998 our directors were granted a total of 240,000 options to
purchase Common Stock at $3.00 per share for a period of ten years. In 1998
and 1999 our executive management was granted a total of 610,000 options to
purchase Common Stock at $4.00 per share for a period of five years. In
1999 our Chief Executive Officer and President was granted 400,000 options
to purchase

                                   14
<PAGE>
Common Stock at $5.00 per share. The options are subject to vesting on
performance standards being met and are exercisable for a period of five years.

NON-QUALIFIED STOCK OPTIONS GRANTED TO EXECUTIVE OFFICERS DURING 1999

     The following table sets forth certain information regarding grants of
stock options to our Executive Officers who received stock options during
1999.  The fair value of the option grant was estimated on the date of the
grant utilizing the Black-Scholes option pricing model with the following
assumptions: 51% to 100% volatility, five year life, risk free rate of
return of 5.5% to 6.2% and a 0% dividend yield.  None of the following
options have been exercised.


<TABLE>
<CAPTION>
                        Number of   % of Total
                        Securities    Options                              Grant Date
                        Underlying  Granted to     Exercise     Grant        Present
Name                     Options     Employees     Price ($)     Date         Value
- ----                     -------     ---------     ---------     ----         -----
                         Granted
                         -------

<S>                      <C>            <C>         <C>        <C>          <C>
Higgins D. Bailey        217,500        25%         $4.00      2/99-11/99   $  680,000

Donald  Hunter           217,500        25%         $4.00      2/99-11/99   $  680,000

Thomas G. Tachovsky      400,000        47%         $5.00      11/99        $1,260,000

Wellington Ewen           20,000         2%         $4.00       6/99        $   60,000
</TABLE>

DIRECTOR COMPENSATION

     Our directors, with the exception of Thomas G. Tachovsky,  receive
$1,000 for each meeting of the Board attended, $500 for participation in
each meeting of the Board by telephonic conference and $500 for
participation, in person or by telephonic conference, in each committee
meeting, and they are reimbursed for out-of-pocket expenses in attending
meetings of the Board of Directors or Committees.  Each director receives
options to purchase 20,000 shares of our Common Stock for each year of
service as a director.

EXECUTIVE EMPLOYMENT AGREEMENTS

     The Company entered an employment agreement with Thomas G. Tachovsky
on December 1, 1999 (the "Employment Agreement"), under which Dr. Tachovsky
serves as the President and Chief Executive Officer of the Company.  Mr.
Tachovsky was granted options in conjunction with the Employment Agreement
to purchase up to 400,000 shares of Common Stock at a purchase price of
$5.00 per share (the "Stock Option Agreement").  Pursuant to the Stock
Option Agreement, 100,000 shares shall vest upon the completion of the
Phase III-A Clinical Trial and a report submission to the FDA, 150,000
shares shall vest upon the completion of the Phase III-B Clinical Trial and
a New Drug Application ("NDA") is submitted to the FDA, and 150,000 shares
shall vest upon FDA approval of the NDA.  In the event of a change of
control, merger or consolidation of the

                                   15
<PAGE>
Company, all unvested options shall become fully vested at the effective
date of such merger, consolidation or change of control.  The Employment
Agreement may be terminated by either party at any time, with or without
cause, by providing written notice and is not for any specific period of
time.  In the event of termination of the Employment Agreement, all non-
vested options shall also be terminated.

MEETINGS AND COMMITTEES OF THE BOARD OF DIRECTORS

     The Board held a total of seven meetings during the fiscal year ended
December 31, 1999.  Each incumbent director attended at least 75% of the
aggregate number of meetings of the Board except Daniel L. Azarnoff who was
unable to attend two meetings and therefore, attended less than 75% of the
aggregate number of meetings of the Board.  Mr. Azarnoff does not serve on
any committee of the Board of Directors.

     The Company has five standing committees: the Executive Committee, the
Audit Committee, the Compensation Committee, the Scientific and Regulatory
Committee and the Nominating Committee.

EXECUTIVE COMMITTEE

     The Executive Committee was formed by the Board to attend to and
report to the Board on day to day operating, financial, regulatory and
other matters.  The committee consists of Thomas G. Tachovsky, Higgins D.
Bailey and Donald Hunter.  The duties of the Executive Committee members
are in addition to their duties as members of the Board.

AUDIT COMMITTEE

     The Audit Committee was formed in March, 2000 pursuant to the Audit
Committee Charter (the "Charter") which is included with this Proxy
Statement.  The Audit Committee attends to and reports to the Board with
respect to matters regarding the Company's independent public accountants,
including, without limitation: annual review of the Charter;  recommending
to the Board of Directors the firm to be engaged as its independent public
accountants for the next fiscal year; reviewing with the Company's
independent public accountants the scope and results of its audit and any
related management letter; consulting with the independent public
accountants and management with regard to the Company's accounting methods
and adequacy of its internal accounting controls; approving the
professional services rendered by the independent public accountants;
reviewing the independence, management consulting services and fees of the
independent public accountants; inquiring about significant risks or
exposures and methods to minimize such risk; ensuring effective use of
audit resources, and preparing and supervising SEC reporting requirements
including an annual Audit Committee report to be included in the Proxy
Statement for each Annual Meeting beginning with fiscal year 2000.  The
Audit Committee currently consists of Messrs. Wilson Benjamin and Joseph R.
Ianelli, who are the independent members of the Audit Committee and Donald
Hunter.  The Audit Committee is required meet at

                                   16
<PAGE>
least four times in each fiscal year.

COMPENSATION COMMITTEE

     The Compensation Committee was formed by the Board to attend to and
report to the Board with respect to the appropriate compensation of
directors and executive officers of the Company and is responsible for
administering all the Company's employee benefit plans.  The Compensation
Committee currently consists of Messrs. Donald Hunter, Daniel L. Azarnoff
and Thomas G. Tachovsky.

SCIENTIFIC AND REGULATORY COMMITTEE

     The Scientific and Regulatory Committee was formed by the Board to
attend to and report to the Board with respect to the planning,
implementation and structure of research and development and with respect
to the progress and requirements of obtaining regulatory approval for the
Company's products.  The Scientific and Regulatory Committee currently
consists of Messrs. Thomas G. Tachovsky, Joseph R. Ianelli, and James E. Wynn.

NOMINATING COMMITTEE

     The Nominating Committee was formed by the Board to attend to and
report to the Board with respect to interviewing, evaluating, nominating
and recommending individuals for membership on the Company's Board of
Directors and committees and nominating specific individuals to be elected
as officers of the Company.   The Nominating Committee currently consists
of Messrs. Higgins D. Bailey, Donald Hunter and Thomas G. Tachovsky.

              RELATED PARTY AND OTHER MATERIAL TRANSACTIONS


     We sublease approximately 800 square feet of office space from Thomas
T. Anderson, one of our principal Shareholders.  The rent on the sublease
is $800 per month.  We believe this is a competitive lease rate for similar
real estate in the area where the office is located.

     In January 1998, we granted Dr. Wynn a non-exclusive right for three
years to develop both improved products and new products from our
proprietary and confidential information.  Improved products are those that
contain the same active ingredients as Esterom(R) solution, but that are
formulated differently.  New products are those which are developed from
cocaine or a derivative and are separately patentable.  We will have all
rights to the improved and new products.  Dr. Wynn will receive a two
percent royalty on the net commercial sales of any improved products he
develops.  The royalty percentage on any new products he develops is to be
determined through negotiation.  If agreement is not reached, the royalty
is to be determined by an arbitrator with pharmaceutical industry experience.

                                   17
<PAGE>
     In April 1998 we entered into an agreement, as amended July 21, 1999,
with Western Center for Clinical Studies ("WCCS") to assist us in
completing the Phase III study and new drug application phase for FDA
approval of Esterom(R) solution for limited range of motion associated with
shoulder injuries and disorders.  We are paying $880,400 over the period
from April 1998 through January 5, 2001, and $76,400 per quarter commencing
January 2001 and continuing until NDA submission.  We also granted WCCS
options to purchase an aggregate of 450,000 shares of our Common Stock at
$1.50 per share for a term of five years.  The options vest at various
times based upon performance.   Daniel L. Azarnoff, M.D.,  a director of
Entropin is also a director of WCCS.

     In November 1999, we entered into an agreement with WCCS to assume our
obligations under our agreement with Therapeutic Management, Inc. to
perform tasks required to comply with FDA regulations applicable to the
conduct, coordination and management of the first Phase III trial.  Among
other things, WCCS is to select investigators, train clinical site
personnel, maintain the master file of all pre-study and study documents,
and prepare the Study Report to be submitted to the FDA.  We will pay WCCS
approximately $350,000 based on completion of certain project goals.

     At the time of the transactions we did not have any independent directors.
However, these transactions are believed to be as favorable as obtainable from
third parties and were approved by directors who did not have an interest
in the transactions.

         SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE

     The Company's directors, its executive officers and persons who own
more than 10% of the Company's Common Stock were not required to comply
with Section 16(a) of the Exchange Act of 1934 during the last fiscal year.


                               PROPOSAL 3
            RATIFICATION OF THE 1998 COMPENSATORY STOCK PLAN
   AND AN AMENDMENT INCREASING THE MAXIMUM  AGGREGATE NUMBER OF SHARES
RESERVED FOR ISSUANCE THEREUNDER TO 500,000 SHARES OF COMMON STOCK

COMPENSATORY STOCK PLAN

     In September 1998 our board of directors authorized the 1998 Stock
Compensatory Plan (the "Plan") which provides for the grant of: (1) shares
of Common Stock as a bonus; and (2) options exercisable to purchase Common
Stock which may be granted in the discretion of the Board as either
"qualified incentive stock options" within the meaning of Section 422 of
the United States Internal Revenue Code of 1986 (the "Code"), or
"nonqualified stock options." Incentive stock options are issuable only to:
(i) employees (including officers and directors) of the Company; (ii)
consultants or independent contractors who are employed by the Company and
who provide valuable services to the Company ("Eligible Persons").   There
are currently seventeen Eligible Persons.  The

                                    18
<PAGE>
purposes of the plan are to attract and retain the best available personnel,
and to provide  additional incentives to Eligible Persons, which will
subsequently promote the success of our business and the interests of
Shareholders.

     We have reserved 300,000 shares of Common Stock for issuance under the
Plan, which is administered by the Compensation Committee and the Board of
Directors.  Under the Plan, the Board of Directors determines which
individuals will receive options or bonus shares, the time period during
which options may be partially or fully exercised, the number of shares of
Common Stock that may be purchased under each option and the option price.
Options granted under the plan are generally exercisable for a period of
five years from the date of grant at an exercise price not less than the
fair market value of the shares at the date of grant.   In the case of
Control Persons, the exercise price for Qualified Options is not less than
110% of the fair market value.  Options granted under the plan generally
vest over a one to three year period from the date of the grant.

     While future issuances are indeterminable, in the most recent fiscal
year we have issued 8,031 bonus shares for services and granted no options
under the Plan.  Shareholder ratification of the Plan is required to allow
options granted under the Plan to be "Qualified Options."  After
ratification, the majority of issuances under the Plan will be "Qualified
Options" so that recipients will receive more favorable tax consequences.
Under Proposal 3, both the Compensatory Stock Plan and the amendment to
increase the  number of shares available under this plan to 500,000 shares
of Common Stock are to be ratified by Shareholders.

     The Board of Directors has voted to authorize an amendment to Section
1.2 (a) of the Compensatory Stock Plan and to recommend such proposed
amendment to the Shareholders for adoption.  A copy of the Compensatory
Stock Plan, as proposed to be amended, is attached hereto and incorporated
herein by this reference.  If this proposal is adopted by the Shareholders,
Section 1.2 (a) of  the Compensatory Stock Plan will be amended to read as
follows:

     (a)  DESCRIPTION OF STOCK AND MAXIMUM SHARE ALLOCATED.  The shares of
     stock subject to the provisions of the Plan and issuable upon the
     grant of Stock Awards or upon the exercise of SARs or Options granted
     under the Plan are shares of the Company's Common Stock, $.001 par
     value per share (the "Stock"), which may be either unissued or
     treasury shares.  The Company may not issue more than 500,000 shares
     of Stock pursuant to the Plan, unless the Plan is amended as provided
     in SECTION 1.3 or the maximum number of shares subject to the Plan is
     adjusted as provided in SECTION 3.1.

     Pursuant to Section 1.3 (a) of the Compensatory Stock Plan, this
amendment requires an affirmative vote of the holders of a majority of the
shares of the Company's Common Stock present in person or by proxy and
voting at the Annual Meeting.  This Proposal 3 shall become effective on the
date of such affirmative vote by the Shareholders.

     THE BOARD OF DIRECTORS BELIEVES THAT PROPOSAL 3 IS IN THE BEST
INTERESTS OF THE COMPANY AND ITS SHAREHOLDERS AND RECOMMENDS A VOTE

                                    19
<PAGE>
FOR APPROVAL OF PROPOSAL 3.

     It is the intention of the persons named in the accompanying form of
Proxy to vote the shares represented thereby in favor of such ratification
unless otherwise instructed in such Proxy.


                               PROPOSAL 4
            RATIFICATION OF SELECTION OF INDEPENDENT AUDITORS

     The Board of Directors of the Company has selected Causey Demgen &
Moore, Inc. to serve as independent accountants for the Company for the
fiscal year ending December 31, 2000. Such firm has examined the financial
statements of the Company since the Company's inception. The Board of
Directors considers Causey Demgen & Moore, Inc. to be well qualified.

     Although it is not required to do so, the Board of Directors is
submitting its selection of the Company's independent accountants for
ratification at the Annual Meeting in order to ascertain the views of
Shareholders regarding such selection. If the selection is not ratified,
the Board of Directors will reconsider its selection.



     THE BOARD OF DIRECTORS RECOMMENDS THAT THE COMPANY'S SHAREHOLDERS VOTE
FOR RATIFICATION OF THE SELECTION OF CAUSEY DEMGEN & MOORE, INC. TO EXAMINE
THE CONSOLIDATED FINANCIAL STATEMENTS OF THE COMPANY FOR THE FISCAL YEAR
ENDING DECEMBER 31, 2000.

     It is the intention of the persons named in the accompanying form of
Proxy to vote the shares represented thereby in favor of such ratification
unless otherwise instructed in such Proxy.

     A representative of Causey Demgen & Moore, Inc. will be present at the
Meeting with the opportunity to make a statement if such representative
desires to do so, and will be available to respond to appropriate questions.

                  FINANCIAL STATEMENTS AND INFORMATION

     The financial statements for the fiscal year ended December 31, 1999
were included in the Company's Form 10-KSB filed with the SEC on March 30,
2000, which is included with this Proxy Statement.

                  SHAREHOLDER PROPOSALS TO BE PRESENTED
                       AT THE NEXT ANNUAL MEETING

     Shareholders interested in presenting a proposal for consideration at
the Company's Annual

                                    20
<PAGE>
Meeting of Shareholders in the year 2001 (the "2001 Annual Meeting") may do
so by following the procedures prescribed in Rule 14a-8 under the Securities
Exchange Act of 1934, as amended (the "Exchange Act"). To be eligible for
inclusion in the Company's 2001 proxy statement, shareholder proposals must
be received by the Company's Secretary no later than February 13, 2001.
Under the rules of the Securities and Exchange Commission, Shareholders
submitting such proposals are required to have held shares of the Company's
Common Stock amounting to at least $2,000 in market value or one percent of
the Common Stock outstanding for at least one year prior to the date on which
such proposals are submitted.  Further, such Shareholders must continue to
own at least that amount of the Company's Common Stock through the date on
which the Annual Meeting is held.


                      TRANSACTION OF OTHER BUSINESS

     At the date of this Proxy Statement, the only business which the Board
of Directors intends to present or knows that others will present at the
meeting is as set forth above.  If any other matter or matters are properly
brought before the meeting, or any adjournment thereof, it is the intention
of the persons named in the accompanying form of proxy to vote the proxy on
such matters in accordance with their best judgement.

                              By Order of the Board of Directors

                              __________________________________________
                              Higgins D. Bailey, Chairman of the Board









                                   21
<PAGE>
                         AUDIT COMMITTEE CHARTER

     The Audit Committee is a committee of the board of directors.  Its
primary function is to assist the board in fulfilling its oversight
responsibilities by reviewing the financial information which will be
provided to the shareholders and others, the systems of internal controls
which management and the board of directors have established, and the audit
process.

     In meeting its responsibilities, the Audit Committee is expected to:

1.   Provide an open avenue of communication between the independent
     accountant and the board of directors and the financial management of
     the Company.

2.   Review and update the Committee's charter annually.

3.   Recommend to the board of directors the independent accountants to be
     nominated, approve the compensation of the independent accountant,
     review and evaluate the performance of the independent accountant and
     approve the discharge of the independent accountant, where appropriate.

4.   Confirm and assure the independence of the independent accountant,
     including a review of management consulting services and related fees
     provided by the independent accountant, requesting a formal written
     statement delineating all relationships between the independent
     accountant and the Company, consistent with Independence Standards
     Board Standard 1, recommending to the board of directors appropriate
     action to ensure the independence of the independent accountant.

5.   Inquire of management and the independent accountant about significant
     risks or exposures and assess the steps management has taken to
     minimize such risk to the Company.

6.   Consider, in consultation with the independent accountant, the audit
     scope and plan of the independent accountant.

7.   Consider with management and the independent accountant the rationale
     for employing audit firms other than the principal independent accountant.

8.   Review with management and the independent accountant the coordination
     of audit effort to assure completeness of coverage, reduction of
     redundant efforts, and the effective use of audit resources.

9.   Consider and review with the independent accountant and the financial
     management of the Company:

          a.   The adequacy of the Company's internal controls including
               computerized information system controls and security.

<PAGE>
          b.   Any related significant findings and recommendations of the
               independent accountant together with management's responses
               thereto.

10.  Review with management and the independent accountant at the
     completion of the annual examination:

          a.   The Company's annual financial statements and related footnotes.

          b.   The independent accountant's audit of the financial
               statements and its report thereon.

          c.   Any significant changes required in the independent
               accountant's audit plan.

          d.   Any serious difficulties or disputes with management
               encountered during the course of the audit.

          e.   Other matters related to the conduct of the audit which are
               to be communicated to the Committee under generally accepted
               auditing standards.

11.  Consider and review with management:

          a.   Significant findings during the year and management's
               responses thereto.

          b.   Any difficulties encountered in the course of the audits,
               including any restrictions on the scope of the work or
               access to required information.

          c.   Any changes required in the planned scope of the audit plan.

12.  Review filings with the SEC and other published documents containing
     the Company's financial statements and consider whether the
     information contained in these documents is consistent with the
     information contained in the financial statements.

13.  Review with management and the independent accountant the interim
     financial report before it is filed with the SEC or other regulators.

14.  Review policies and procedures with respect to officers' expense
     accounts and perquisites, including their use of corporate assets, and
     consider the results of any review of those areas by the independent
     accountant.

15.  Review legal and regulatory matters that may have a material impact on
     the financial statements, related Company compliance policies, and
     programs and reports received from regulators.

                                    2

<PAGE>
16.  Meet with the independent accountant and management in separate
     executive sessions to discuss any matters that the Committee or these
     groups believe should be discussed privately with the Audit Committee.

17.  Report Committee actions to the board of directors with such
     recommendations as the Committee may deem appropriate.

18.  Prepare a letter for inclusion in the annual report that describes the
     Committee's composition and responsibilities, and how they were
     discharged.

19.  Prepare a report, as prescribed by SEC Rules, to be included in the
     Company's annual proxy or information statement, stating, among other
     things:

          a.   whether the Committee has reviewed and discussed the audited
               financial statements with management;

          b.   whether the Committee has discussed with the independent
               accountant the matters required to be discussed by SAS 61,
               as modified or supplemented;

          c.   whether the Committee has received the written disclosures
               and the letter from the independent accountant required by
               Independence Standards Board Standard No. 1, as may be
               modified or supplemented, and

          d.   whether the Committee has discussed with the independent
               accountant the independent accountant's independence;

          e.   whether, based upon the review and discussions in
               subparagraphs a. through d., above, the Committee
               recommended to the board that the audited financial
               statements be included in the Company's Annual Report on
               Form 10-KSB for the last fiscal year for filing with the
               SEC; and

          f.   the name of each member of the Committee below the above
               information in the Report.

20.  The Audit Committee shall consult with the independent accountant to
     ensure that the independent accountant reviews the financial
     information included in the Company's Quarterly Reports on Form 10-Q
     or 10-QSB prior to the Company's filing such reports with the SEC.

21.  The Audit Committee shall have the power to conduct or authorize
     investigations into any matters within the Committee's scope of
     responsibilities.  The Committee shall be empowered to retain
     independent counsel, accountants, or others to assist it in the con-
     duct of any investigation.

                                    3
<PAGE>
22.  The Committee shall meet at least four times per year or more
     frequently as circumstances require.  The Committee may ask members of
     management or others to attend the meeting and provide pertinent
     information as necessary.

23.  The Committee will perform such other functions as assigned by law,
     the Company's charter or bylaws, or the board or directors.

     The membership of the Audit Committee shall consist of at least two
members, a majority of which shall be independent members of the board of
directors who shall serve at the pleasure of the board of directors.  Audit
Committee members and the Committee chairman shall be designated by the
full board of directors.

     The duties and responsibilities of a member of the Audit Committee are
in addition to those duties set out for a member of the board of directors.









                                    4
<PAGE>
                             ENTROPIN, INC.
                      1998 COMPENSATORY STOCK PLAN

                                ARTICLE I

     1.1  PURPOSE OR PLAN; TERM.

          (a)  ADOPTION.  On September 11, 1998 (the "Adoption Date"), the
Board of Directors (the "Board") of Entropin, Inc., a Colorado corporation
(the "Company"), adopted this stock option plan to be known as the 1998
Compensatory Stock Plan (the "Plan").

          (b)  DEFINED TERMS.  All initially capitalized terms used hereby
shall have the meaning set forth in ARTICLE IV hereto.

          (c)  GENERAL PURPOSE.   This 1998 Compensatory Stock Plan is
intended to encourage stock ownership by employees, officers, directors of
and consultants to Entropin, Inc. and its controlled, affiliated subsidiary
corporations (collectively, the "Company"), so that they may acquire or
increase their proprietary interest in the Company, and is intended to
facilitate the Company's efforts to (i) induce qualified persons to become
employees or officers of or consultants to the Company; (ii) compensate
employees, officers, directors and consultants for services to the Company;
and (iii) encourage such persons to remain in the employ of or associated
with the Company and to put forth maximum efforts for the success of the
Company. Such purpose shall be accomplished by providing for the
discretionary granting of options to acquire the Company's Stock
("Options"), the direct granting of the Company's Stock ("Stock Awards"),
and the granting of stock appreciation rights ("SARs"), (Stock Awards and
SARs shall be collectively referred to herein as "Awards").

          (d)  CHARACTER OF OPTIONS.  Options granted under this Plan to
employees of the Company (or Parent or Subsidiary Corporations) that are
intended to qualify as an "incentive stock option" as defined in Code
section 422 ("Incentive Stock Option") will be specified in the applicable
stock option agreement. All other Options granted under this Plan will be
non-qualified options.

          (e)  RULE 16b-3 PLAN.  The Plan is intended to comply with all
applicable conditions of Rule 16b-3 (and all subsequent revisions thereof)
promulgated under the Securities Exchange Act of 1934 (the "Act").  In such
instance, to the extent any provision of the Plan or action by a Committee
or the Board fails to so comply, it shall be deemed null and void, to the
extent permitted by law and deemed advisable by the Board or such
Committee.  In addition, the Board may amend the Plan from time to time as
it deems necessary in order to meet the requirements of any amendments to
Rule 16b-3 without the consent of the shareholders of the Company.

          (f)  DURATION OF PLAN.  The term of the Plan is 10 years,
commencing on the date of adoption of the original Plan by the Board as
specified in SECTION 1.1(a) hereof.  No Option or Award shall be granted
under the Plan unless granted within 10 years of the adoption of the Plan
by the Board, but Options or Awards outstanding on that date shall not be
terminated or otherwise affected by virtue of the Plan's expiration.

<PAGE>
     1.2  STOCK AND MAXIMUM NUMBER OF SHARES SUBJECT TO PLAN.

          (a)  DESCRIPTION OF STOCK AND MAXIMUM SHARES ALLOCATED.  The
shares of stock subject to the provisions of the Plan and issuable upon the
grant of Stock Awards or upon the exercise of SARs or Options granted under
the Plan are shares of the Company's Common Stock, $.001 par value per
share (the "Stock"), which may be either unissued or treasury shares.  The
Company may not issue more than 300,000 shares of Stock pursuant to the
Plan, unless the Plan is amended as provided in SECTION 1.3 or the maximum
number of shares subject to the Plan is adjusted as provided in SECTION 3.1.

          (b)  CALCULATION OF AVAILABLE SHARES.  The number of shares of
Stock available under the Plan shall be reduced: (i) by any shares of Stock
issued (including any shares of Stock withheld for tax withholding
requirements) upon exercise of an Option; and, (ii) by any shares of Stock
issued (including any shares of Stock withheld for tax withholding
requirements) upon the grant of a Stock Award or the exercise of an SAR.

          (c)  RESTORATION OF UNPURCHASED SHARES.  If an Option or SAR
expires or terminates for any reason prior to its exercise in full and
before the term of the Plan expires, the shares of Stock subject to, but
not issued under, such Option or SAR shall, without further action or by or
on behalf of the Company, again be available under the Plan.

     1.3  APPROVAL; AMENDMENTS.

          (a)  APPROVAL BY STOCKHOLDERS.  The Plan shall be submitted to
the stockholders of the Company for their approval at a regular or special
meeting to be held within 12 months after the adoption of the Plan by the
Board.  Stockholder approval shall be evidenced by the affirmative vote of
the holders of a majority of the shares of the Company's Common Stock
present in person or by proxy and voting at the meeting. The date such
stockholder approval has been obtained shall be referred to herein as the
"Effective Date."

          (b)  COMMENCEMENT OF PLAN.  The Plan is effective immediately,
but if the Plan is not approved by the stockholders within 12 months after
its adoption by the Board, all Incentive Stock Options made thereunder
shall lose their status as incentive stock options as defined in   Section
422(b) of the Code, and shall automatically become non-qualified stock
options; provided, however, that the failure to adopt the Plan by
shareholders shall not effect any non-qualified options and Awards
previously granted herein.

          (c)  AMENDMENTS TO PLAN. The Board may, without action on the
part of the Company's stockholders, terminate or make such amendments to,
changes in and additions to the Plan as it may, from time to time, deem
necessary or appropriate and in the best interests of the Company;
provided, the Board may not, without the consent of the applicable
Optionholder, take any action which disqualifies any Option previously
granted under the Plan for treatment as an Incentive Stock Option or which
adversely affects or impairs the rights of the Optionholder of any Option
outstanding under the Plan, except as provided in Paragraph 1.3 (b), and
further provided

                                    2
<PAGE>
that, except as provided in ARTICLE III hereof, the Board may not, without
the approval of the Company's stockholders: (i) increase the aggregate
number of shares of Stock subject to the Plan; (ii) reduce the exercise
price at which Options may be granted or the exercise price at which any
outstanding Option may be exercised; (iii) extend the term of the Plan;
(iv) change the class of persons eligible to receive Options or Awards
under the Plan; or, (v) materially increase the benefits accruing to
participants under the Plan. Notwithstanding the foregoing, Options or
Awards may be granted under this Plan to purchase shares of Stock in excess
of the number of shares then available for issuance under the Plan if (A)
an amendment to increase the maximum number of shares issuable under the
Plan is adopted by the Board prior to the initial grant of any such Option
or Award and within one year thereafter such amendment is approved by the
Company's stockholders and (B) each such Option or Award granted does not
become exercisable or vested, in whole or in part, at any time prior to the
obtaining of such stockholder approval.

                               ARTICLE II

     2.1  PARTICIPANTS; ADMINISTRATION.

          (a)  ELIGIBILITY AND PARTICIPATION.  Options and Awards may be
granted only to persons ("Eligible Persons") who at the time of grant are:
(i) employees (including officers and directors) of the Company or Parent
or Subsidiary Corporations; or, (ii) consultants or independent contractors
who provide valuable services to the Company or Parent or Subsidiary
Corporations; provided that Incentive Stock Options may only be granted to
employees of the Company (and its Parent or Subsidiary Corporations).  The
Committee shall have full authority to determine which Eligible Persons are
to receive Option grants under the Plan, the number of shares to be covered
by each such grant, whether or not the granted Option is to be an Incentive
Stock Option, the time or times at which each such Option is to become
exercisable, and the maximum term for which the Option is to be
outstanding. The Committee shall also have full authority to determine
which Eligible Persons are to receive Awards and the conditions relating to
such Award.

          (b)  GENERAL ADMINISTRATION.  The Plan shall be administered by
the Compensation Committee which shall make recommendations to the Board of
Directors with respect to the grant of Options and Awards.  The Board of
Directors retains complete authority in its discretion, subject to and not
inconsistent with the express provisions of the Plan, to grant Options and
Awards pursuant to the Plan. The Committee shall administer the Plan and
make recommendations to the Board concerning the following: exercise of all
powers and authorities either specifically conferred under the Plan or
necessary or advisable in the administration of the Plan:  to determine the
vesting schedule and other restrictions, if any, relating to Options and
Awards; to determine the Option Price; to determine the persons to whom,
and the time or times at which, Options and Awards shall be granted; to
determine the number of shares to be covered by each Option or Award; to
determine Fair Market Value per share; to interpret the Plan; to prescribe,
amend and rescind rules and regulations relating to the Plan; to determine
the terms and provisions of the Option agreements (which need not be
identical) entered into in connection with Options granted under the Plan;
and to make all other determinations deemed necessary or advisable for the
administration of the Plan.  The Committee may delegate to one or more of
its members or to one

                                    3
<PAGE>
or more agents such administrative duties as it may deem advisable, and the
Committee or any person to whom it has delegated duties as aforesaid may
employ one or more persons to render advice with respect to any
responsibility the Committee or such person may have under the Plan.

          (c)  Options and Awards granted under the Plan shall be evidenced
by duly adopted resolutions of the Committee included in the minutes of the
meeting at which they are adopted or in a unanimous written consent.

          (d)  No member of the Committee or the Board shall be liable for
any action taken or determination made in good faith with respect to the
Plan or any Option or Award granted hereunder.

          (e)  In designating and selecting Eligible Persons for
participation in the Plan, the Committee shall consult with and give
consideration to the recommendations and criticisms submitted by
appropriate managerial and executive officers of the Company.  The
Committee also shall take into account the duties and responsibilities of
the Eligible Persons, their past, present and potential contributions to
the success of the Company and such other factors as the Committee shall
deem relevant in connection with accomplishing the purpose of the Plan.

     2.2  TERMS AND CONDITIONS OF OPTIONS.

          (a)  ALLOTMENT OF SHARES. The Committee shall determine the
number of shares of Stock to be optioned from time to time and the number
of shares to be optioned to any Eligible Person (the "Optioned Shares").
The grant of a Option to a person shall neither entitle such person to, nor
disqualify such person from, participation in any other grant of Options or
Awards under this Plan or any other stock option plan of the Company.

          (b)  EXERCISE PRICE. Upon the grant of any Option, the Committee
shall specify the option price per share. If the Option is intended to
qualify as an Incentive Stock Option under the Code, the option price per
share may not be less than 100 percent of the fair market value per share
of the stock on the date the Option is granted (110 percent if the Option
is granted to a stockholder who at the time the Option is granted owns or
is deemed to own stock possessing more than 10 percent of the total
combined voting power of all classes of stock of the Company or of any
Parent or Subsidiary Corporation). If the Option is not intended to qualify
as an Incentive Stock Option under the Code, the option price per share may
not be less than 85 percent of the fair market value per share of the stock
on the date the Option is granted.  The determination of the fair market
value of the Stock shall be made in accordance with the valuation
provisions of SECTION 3.5 hereof.

          (c)  INDIVIDUAL STOCK OPTION AGREEMENTS.  Options granted under
the Plan shall be evidenced by option agreements in such form and content
as the Committee from time to time approves, which agreements shall
substantially comply with and be subject to the terms of the Plan,
including the terms and conditions of this SECTION 2.2.  As determined by
the Committee, each option agreement shall state: (i) the total number of
shares to which it pertains; (ii) the exercise price for the shares covered
by the Option; (iii) the time at which the Options vest and become exercisable;

                                    4
<PAGE>
and, (iv) the Option's scheduled expiration date.  The option agreements
may contain such other provisions or conditions as the Committee deems
necessary or appropriate to effectuate the sense and purpose of the Plan,
including covenants by the Optionholder not to compete and remedies for the
Company in the event of the breach of any such covenant.

          (d)  OPTION PERIOD.  No Option granted under the Plan that is
intended to be an Incentive Stock Option shall be exercisable for a period
in excess of 10 years from the date of its grant (five years if the Option
is granted to a shareholder who at the time the Option is granted owns or
is deemed to own stock possessing more than 10 percent of the total
combined voting power of all classes of stock of the Company or of any
Subsidiary Corporation), subject to earlier termination in the event of
termination of employment, retirement or death of the Optionholder.  An
Option may be exercised in full or in part at any time or from time to time
during the term of the Option or provide for its exercise in stated
installments at stated times during the Option's term.

          (e)  VESTING; LIMITATIONS. The time at which Options vest with
respect to an Optionholder shall be in the discretion of that
Optionholder's Committee; provided that no Options shall vest prior to the
Effective Date.  Notwithstanding the foregoing, to the extent a Option is
intended to qualify as an Incentive Stock Option, the aggregate fair market
value (determined as of the respective date or dates of grant) of the Stock
for which one or more Options granted to any person under this Plan (or any
other option plan of the Company or its Parent or Subsidiary Corporations)
may for the first time become exercisable as Incentive Stock Options during
any one calendar year shall not exceed the sum of $100,000 (referred to
herein as the "$100,000 Limitation"). To the extent that any person holds
two or more Options which become exercisable for the first time in the same
calendar year, the foregoing limitation on the exercisability as an
Incentive Stock Option shall be applied on the basis of the order in which
such Options are granted.

          (f)  NO FRACTIONAL SHARES.  Options shall be exercisable only for
whole shares; no fractional shares will be issuable upon exercise of any
Option granted under the Plan.

          (g)  METHOD OF EXERCISE.  To exercise a Option, an Optionholder
(or in the case of an exercise after an Optionholder's death, such
Optionholder's executor, administrator, heir or legatee, as the case may
be) must take the following action:

               (i)  execute and deliver to the Company a written notice of
exercise signed in writing by the person exercising the Option specifying
the number of shares of Stock with respect to which the Option is being
exercised;

               (ii) pay the aggregate Option Price in one of the alternate
forms as set forth in SECTION 2.2(h) below; and,

               (iii) furnish appropriate documentation that the person or
persons exercising the Option (if other than the Optionholder) has the
right to exercise such Option.

                                    5
<PAGE>
     As soon as practical after the Exercise Date, the Company will mail or
deliver to or on behalf of the Optionholder (or any other person or persons
exercising this Option under the Plan) a certificate or certificates
representing the Stock acquired upon exercise of the Option.

          (h)  PAYMENT PRICE. The aggregate Option Price shall be payable
in one of the alternative forms specified below:

               (i)  Full payment in cash or check made payable to the
Company's order;

               (ii) At the Company's option, full payment in shares of
Stock held for the requisite period necessary to avoid a charge to the
Company's reported earnings and valued at fair market value on the Exercise
Date (as determined in accordance with SECTION 3.5 hereof); or,

               (iii) At the Company's option, if a cashless exercise Plan
has been implemented by the Board, full payment through a sale and
remittance procedure pursuant to which the Optionholder (A) shall provide
irrevocable written instructions to a designated brokerage firm to effect
the immediate sale of the Optioned Shares to be purchased and remit to the
Company, out of the sale proceeds available on the settlement date,
sufficient funds to cover the aggregate exercise price payable for the
Optioned Shares to be purchased and (B) shall concurrently provide written
directives to the Company to deliver the certificates for the Optioned
Shares to be purchased directly to such brokerage firm in order to complete
the sale transaction.

          (i)  RIGHTS OF A STOCKHOLDER.  An Optionholder shall not have any
of the rights of a stockholder with respect to Optioned Shares until such
individual shall have exercised the Option and paid the Option Price for
the Optioned Shares. No adjustment will be made for dividends or other
rights for which the record date is prior to the date such stock
certificate is issued.

          (j)  REPURCHASE RIGHT.  The Committee may, in its sole
discretion, set forth other terms and conditions upon which the Company (or
its assigns) shall have the right to repurchase shares of Stock acquired by
an Optionholder pursuant to a Option.  Any repurchase right of the Company
shall be exercisable by the Company (or its assignees) upon such terms and
conditions as the Committee may specify in a stock repurchase agreement in
such form and content as the Committee may approve evidencing such right.
The Committee may also in its discretion establish as a term and condition
of one or more Options granted under the Plan that the Company shall have
a right of first refusal with respect to any proposed sale or other
disposition by the Optionholder of any shares of Stock issued upon the
exercise of such Options.  Any such right of first refusal shall be
exercisable by the Company (or its assigns) in accordance with the terms
and conditions set forth in a stock repurchase agreement.

          (k)  TERMINATION OF SERVICE.  If any Optionholder ceases to be in
Service to the Company for a reason other than permanent disability or
death, such Optionholder must, within 90 days after the date of termination
of such Service, but in no event after the Option's stated expiration date,
exercise some or all of the Options that the Optionholder was entitled to
exercise on the date the Optionholder's Service terminated; provided, that
if the Optionholder is discharged for Cause

                                    6
<PAGE>
or commits acts detrimental to the Company's interests after the Service of
the Optionholder has been terminated, then the Option will thereafter be
void for all purposes. "Cause" shall mean a termination of Service based
upon a finding by the applicable Committee that the Optionholder: (i) has
committed a felony involving dishonesty, fraud, theft or embezzlement; (ii)
after written notice from the Company, has repeatedly failed or refused, in
a material respect, to follow reasonable policies or directives established
by the Company; (iii) after written notice from the Company, has willfully
and persistently failed to attend to material duties or obligations; (iv)
has performed an act or failed to act, which, if he were prosecuted and
convicted, would constitute a theft of money or property of the Company;
or, (v) has misrepresented or concealed a material fact for purposes of
securing employment with the Company.  If any Optionholder ceases to be in
Service to the Company by reason of permanent disability within the meaning
of section 22(e)(3) of the Code (as determined by the applicable
Committee), the Optionholder will have 12 months after the date of
termination of Service, but in no event after the stated expiration date of
the Optionholder's Options, to exercise Options that the Optionholders was
entitled to exercise on the date the Optionholder's Service terminated as
a result of the disability.

          (l)  DEATH OF OPTIONHOLDER.  If an Optionholder dies while in the
Company's Service, any Options that the Optionholder was entitled to
exercise on the date of death will be exercisable within the six-month
period following the date of issuance of letters testamentary or letters of
administration of a deceased Optionholder, in the case of the
Optionholder's death during his employment by the Company, but not later
than one year after the Optionholder's death or until the stated expiration
date of the Optionholder's Option, whichever occurs first, by the person or
persons ("successors") to whom the Optionholder's rights pass under a will
or by the laws of descent and distribution. As soon as practicable after
receipt by the Company of such notice and of payment in full of the Option
Price, a certificate or certificates representing the Optioned Shares shall
be registered in the name or names specified by the successors in the
written notice of exercise and mall be delivered to the successors.

          (m)  OTHER PLAN PROVISIONS STILL APPLICABLE.  If a Option is
exercised upon the termination of Service or death of an Optionholder under
this SECTION 2.2, the other provisions of the Plan will continue to apply
to such exercise, including the requirement that the Optionholder or its
successor may be required to enter into a Stock Repurchase Agreement.

          (n)  DEFINITION OF "SERVICE".  For purposes of this Plan, unless
it is evidenced otherwise in the option agreement with the Optionholder,
the Optionholder is deemed to be in "Service" to the Company so long as
such individual renders continuous services on a periodic basis to the
Company (or to any Parent or Subsidiary Corporation) in the capacity of an
employee, director, or an independent consultant or advisor. In the
discretion of the applicable Committee, an Optionholder will be considered
to be rendering continuous services to the Company even if the type of
services change, e.g., from employee to independent consultant.  The
Optionholder will be considered to be an employee for so long as such
individual remains in the employ of the Company or one or more of its
Parent or Subsidiary Corporations.

                                    7
<PAGE>
     2.3  TERMS AND CONDITIONS OF STOCK AWARDS.

          (a)  ELIGIBILITY.  All Eligible Persons shall be eligible to
receive Stock Awards. The Committee shall determine the number of shares of
Stock to be awarded from time to time to any Eligible Person. Except as
provided otherwise in this Plan, the grant of a Stock Award to a person (a
"Grantee") shall neither entitle such person to, nor disqualify such person
from participation in, any other grant of options or awards by the Company,
whether under this Plan or under any other stock option or award plan of
the Company.

          (b)  AWARD FOR SERVICES RENDERED.  Stock Awards shall be granted
in recognition of an Eligible Person's services to the Company. The grantee
of any such Stock Award shall not be required to pay any consideration to
the Company upon receipt of such Stock Award, except as may be required to
satisfy any applicable corporate law, employment tax and/or income tax
withholding requirements.

          (c)  CONDITIONS TO AWARD.  All Stock Awards shall be subject to
such terms, conditions, restrictions, or limitations as the Committee deems
appropriate, including, by way of illustration but not by way of
limitation, restrictions on transferability, requirements of continued
employment, individual performance or the financial performance of the
Company, or payment by the recipient of any applicable employment or
withholding taxes.  Such Committee may modify or accelerate the termination
of the restrictions applicable to any Stock Award under the circumstances
as it deems appropriate.

          (d)  AWARD AGREEMENTS.  The Committee may require as a condition
to a Stock Award that the recipient of such Stock Award enter into an award
agreement in such form and content as that Committee from time to time approves.

     2.4  TERMS AND CONDITIONS OF SARS.

          (a)  ELIGIBILITY.  All Eligible Persons shall be eligible to
receive SARs.   The Committee shall determine the SARs to be awarded from
time to time to any Eligible Person. The grant of a SAR to a person shall
neither entitle such person to, nor disqualify such person from
participation in, any other grant of options or awards by the Company,
whether under this Plan or under any other stock option or award plan of
the Company.

          (b)  AWARD OF SARS.  Concurrently with or subsequent to the grant
of any Option to purchase one or more shares of Stock, the Committee may
award to the Optionholder with respect to each share of Stock, underlying
the Option, a related SAR permitting the Optionholder to be paid any
appreciation on that Stock in lieu of exercising the Option.  In addition,
a Committee may award to any Eligible Person a SAR permitting the Eligible
Person to be paid the appreciation on a designated number of shares of the
Stock, whether or not such Shares are actually issued.

          (c)  CONDITIONS TO SAR. All SARs shall be subject to such terms,
conditions, restrictions or limitations as the Committee deems appropriate,
including, by way of illustration but

                                    8
<PAGE>
not by way of limitation, restrictions on transferability, requirements of
continued employment, individual performance, financial performance of the
Company, or payment by the recipient of any applicable employment or
withholding taxes. The Committee may modify or accelerate the termination
of the restrictions applicable to any SAR under the circumstances as it
deems appropriate.

          (d)  SAR AGREEMENTS.  The Committee may require as a condition to
the grant of a SAR that the recipient of such SAR enter into a SAR
agreement in such form and content as that Committee from time to time approves.

          (e)  EXERCISE.  An Eligible Person who has been granted a SAR may
exercise such SAR subject to the conditions specified in the SAR agreement
by the Committee.

          (f)  AMOUNT OF PAYMENT. The amount of payment to which the
grantee of a SAR shall be entitled upon the exercise of each SAR shall be
equal to the amount, if any, by which the fair market value of the
specified shares of Stock on the exercise date exceeds the fair market
value of the specified shares of Stock on the date the Option related to
the SAR was granted or became effective, or, if the SAR is not related to
any Option, on the date the SAR was granted or became effective.

          (g)  FORM OF PAYMENT. The SAR may be paid in either cash or
Stock, as determined in the discretion of the Committee and set forth in
the SAR agreement. If the payment is in Stock, the number of shares to be
paid to the participant shall be determined by dividing the amount of the
payment determined pursuant to SECTION 2.4(f) by the fair market value of
a share of Stock on the exercise date of such SAR. As soon as practical
after exercise, the Company shall deliver to the SAR grantee a certificate
or certificates for such shares of Stock.

          (h)  TERMINATION OF EMPLOYMENT; DEATH.  SECTIONS 2.2(k) AND (1),
applicable to Options, shall apply equally to SARs.

                               ARTICLE III

     3.1  CAPITAL ADJUSTMENTS. The aggregate number of shares of Stock
subject to the Plan, the number of shares of Stock covered by outstanding
Options and Awards, and the price per share stated in all outstanding
Options and Awards shall be proportionately adjusted for any increase or
decrease in the number of outstanding shares of Stock of the Company
resulting from a subdivision or consolidation of shares or any other
capital adjustment or the payment of a stock dividend or any other increase
or decrease in the number of such shares effected without the Company's
receipt of consideration therefor in money, services or property.

     3.2  MERGERS, ETC.  If the Company is the surviving corporation in any
merger or consolidation (not including a Corporate Transaction), any Option
or Award granted under the Plan shall pertain to and apply to the
securities to which a holder of the number of shares of Stock subject to
the Option or Award would have been entitled prior to the merger or
consolidation.  Except as

                                    9
<PAGE>
provided in SECTION 3.3 hereof, a dissolution or liquidation of the Company
shall cause every Option or Award outstanding hereunder to terminate.

     3.3  CORPORATE TRANSACTION. In the event of stockholder approval of a
Corporate Transaction, the Committee shall have the discretion and
authority, exercisable at any time, to provide for the automatic
acceleration of one or more of the outstanding Options or Awards granted by
it under the Plan.  Upon the consummation of the Corporate Transaction, all
Options shall, to the extent not previously exercised, terminate and cease
to be outstanding.

     3.4  CHANGE IN CONTROL.

          (a)  In the event of a Change in Control, the Committee shall
have the discretion and authority, exercisable at any time, whether before
or after the Change in Control, to provide for the automatic acceleration
of one or more outstanding Options or Awards granted by it under the Plan
upon the occurrence of such Change in Control.  The Committee may also
impose limitations upon the automatic acceleration of such Options or
Awards to the extent it deems appropriate. Any Options or Awards
accelerated upon a Change in Control will remain fully exercisable until
the expiration or sooner termination of the Option term.

          (b)  INCENTIVE STOCK OPTION LIMITS. The exercisability of any
Options which are intended to qualify as Incentive Stock Options and which
are accelerated by the Committee in connection with a pending Corporation
Transaction or Change in Control shall, except as otherwise provided in the
discretion of the Committee and the Optionholder, remain subject to the
$100,000 Limitation and vest as quickly as possible without violating the
$100,000 Limitation.

     3.5  CALCULATION OF FAIR MARKET VALUE OF STOCK.  The fair market value
of a share of Stock on any relevant date shall be determined in accordance
with the following provisions:

          (a)  If the Stock is not at the time listed or admitted to
trading on any stock exchange but is traded in the over-the-counter market,
the fair market value shall be the mean between the highest bid and lowest
asked prices (or, if such information is available, the closing selling
price) per share of Stock on the date in question in the over-the-counter
market, as such prices are reported by the National Association of
Securities Dealers through its NASDAQ system or any successor system. If
there are no reported bid and asked prices (or closing selling price) for
the Stock on the date in question, then the mean between the highest bid
price and lowest asked price (or the closing selling price) on the last
preceding date for which such quotations exist shall be determinative of
fair market value.

          (b)  If the Stock is at the time listed or admitted to trading on
any stock exchange, then the fair market value shall be the closing selling
price per share of Stock on the date in question on the stock exchange
determined by the Board to be the primary market for the Stock, as such
price is officially quoted in the composite tape of transactions on such
exchange.  If there is no reported sale of Stock on such exchange on the
date in question, then the fair market value shall be the closing selling
price on the exchange on the last preceding date for which such quotation
exists.

                                   10
<PAGE>
          (c)  If the Stock at the time is neither listed nor admitted to
trading on any stock exchange nor traded in the over-the-counter market,
then the fair market value shall be determined by the Board after taking
into account such factors as the Board shall deem appropriate, including
one or more independent professional appraisals.

     3.6  USE OF PROCEEDS.  The proceeds received by the Company from the
sale of Stock pursuant to the exercise of Options or Awards hereunder, if
any, shall be used for general corporate purposes.

     3.7  CANCELLATION OF OPTIONS.  The Committee shall have the authority
to effect, at any time and from time to time, with the consent of the
affected Optionholders, the cancellation of any or all outstanding Options
granted under the Plan by that Committee and to grant in substitution
therefore new Options under the Plan covering the same or different numbers
of shares of Stock as long as such new Options have an exercise price per
share of Stock no less than the minimum exercise price as set forth in
SECTION 2.2(b) hereof on the new grant date.

     3.8  REGULATORY APPROVALS.  The implementation of the Plan, granting
of any Option or Award hereunder, and the issuance of Stock upon the
exercise of any such Option or Award shall be subject to the procurement by
the Company of all approvals and permits required by regulatory authorities
having jurisdiction over the Plan, the Options or Awards granted under it
and the Stock issued pursuant to it.

     3.9  INDEMNIFICATION.  In addition to such other rights of
indemnification as they may have, the members of the Committee shall be
indemnified and held harmless by the Company, to the extent permitted under
applicable law, for, from and against all costs and expenses reasonably
incurred by them in connection with any action, legal proceeding to which
any member thereof may be a party by reason of any action taken, failure to
act under or in connection with the Plan or any rights granted thereunder
and against all amounts paid by them in settlement thereof or paid by them
in satisfaction of a judgment of any such action, suit or proceeding,
except a judgment based upon a finding of bad faith.

     3.10 PLAN NOT EXCLUSIVE.  This Plan is not intended to be the
exclusive means by which the Company may issue options or warrants to
acquire its Stock, stock awards or any other type of award.  To the extent
permitted hy applicable law, any such other option, warrants or awards may
he issued by the Company other than pursuant to this Plan without
shareholder approval.

     3.11 COMPANY RIGHTS.  The grants of Options shall in no way affect the
right of the Company to adjust, reclassify, reorganize or otherwise change
its capital or business structure or to merge, consolidate, dissolve,
liquidate or sell or transfer all or any part of its business or assets.

     3.12 ASSIGNMENT.  The right to acquire Stock or other assets under the
Plan may not be assigned, encumbered or otherwise transferred by any
Optionholder except as specifically provided herein. No Option or Award
granted under the Plan or any of the rights and privileges conferred

                                   11
<PAGE>
thereby shall be assignable or transferable by an Optionholder or grantee
other than by will or the laws of descent and distribution, and such Option
or Award shall be exercisable during the Optionholder's or grantee's
lifetime only by the Optionholder or grantee.  Notwithstanding the
foregoing, any Options or Awards granted pursuant to the Plan may be
assigned, encumbered or otherwise transferred by the Optionholder or
grantee if specifically allowed by the Committee upon the grant of such
Option or Award. The provisions of the Plan shall inure to the benefit of,
and be binding upon, the Company and its successors or assigns, and the
Optionholders. the legal representatives of their respective estates, their
respective heirs or legatees and their permitted assignees.

     3.13 SECURITIES REGISTRATION.

          (a)  LEGEND ON CERTIFICATES.  All certificates representing
shares of Stock issued under the Plan shall be endorsed with a legend
reading as follows:

     The shares of Common Stock evidenced by this certificate have been
     issued to the registered owner in reliance upon written
     representations that these shares have been purchased solely for
     investment.  These shares may not he sold, transferred or assigned
     unless in the opinion of the Company and its legal counsel such sale,
     transfer or assignment will not be in violation of the Securities Act
     of 1933, as amended, and the rules and regulations thereunder.

          (b)  PRIVATE OFFERING FOR INVESTMENT ONLY.  The Options and
Awards are and shall be made available only to a limited number of present
and future executives, directors, employees and/or consultants who have
knowledge of the Company's financial condition, management and its affairs.
The Plan is not intended to provide additional capital for the Company, but
to encourage ownership of Stock among the Company's employees.  By the act
of accepting an Option or Award, each grantee agrees: (i) that, any shares
of Stock acquired will be solely for investment not with any intention to
resell or redistribute those shares; and, (ii) such intention will be
confirmed by an appropriate certificate at the time the Stock is acquired
if requested by the Company. The neglect or failure to execute such a
certificate, however, shall not limit or negate the foregoing agreement.

          (c)  REGISTRATION STATEMENT.  If a Registration Statement
covering the shares of Stock issuable under the Plan as filed under the
Securities Exchange Act of 1933, as amended, and as declared effective by
the Securities Exchange Commission, the provisions of SECTIONS 3.13(a) AND
(b) shall terminate during the period of time that such Registration
Statement, as periodically amended, remains effective.

     3.14 TAX WITHHOLDING.

          (a)  GENERAL. The Company's obligation to deliver Stock under the
Plan shall be subject to the satisfaction of all applicable federal, state
and local income tax withholding requirements.

                                   12
<PAGE>
          (b)  SHARES TO PAY FOR WITHHOLDING. The Board may, in its
discretion and in accordance with the provisions of this SECTION 3.14(b)
and such supplemental roles as it may from time to time adopt (including
the applicable safe-harbor provisions of SEC Rule 16b-3), provide any or
all Optionholders or Grantees with the right to use shares of Stock in
satisfaction of all or part of the federal, state and local income tax
liabilities incurred by such Optionholders or Grantees in connection with
the receipt of Stock ("Taxes"). Such right may be provided to any such
Optionholder or Grantee in either or both of the following formats:

               (i)  STOCK WITHHOLDING.  An Optionholder or Grantee may be
provided with the election, which may be subject to approval by the
Committee, to have the Company withhold, from the Stock otherwise issuable,
a portion of those shares of Stock with an aggregate fair market value
equal to the percentage of the applicable Taxes (not to exceed 100 percent)
designated by the Optionholder or Grantee.

               (ii) STOCK DELIVERY.  The Board may, in its discretion,
provide the Optionholder or Grantee with the election to deliver to the
Company, at the time the Option is exercised or Stock is awarded, one or
more shares of Stock previously acquired by such individual (other than
pursuant to the transaction triggering the Taxes) with an aggregate fair
market value equal to the percentage of applicable taxes incurred in
connection with such Option exercise or Stock Award (not to exceed 100
percent) designated by the Optionholder or Grantee.

     3.15 GOVERNING LAW. The Plan shall be governed by and all questions
hereunder shall he determined in accordance with the laws of the State of
Colorado.

                               ARTICLE IV
                               DEFINITIONS

     The following capitalized terms used in this Plan shall have the
meaning described below:

"AFFILIATES" shall mean all "executive officers" (as that term is defined
in Rule 16a-1(f) promulgated under the Act) and directors of the Company
and all persons who own ten percent or more of the Company's issued and
outstanding Stock.

"AWARD" shall mean a Stock Award or SAR under the Plan.

"BOARD" shall mean the Board of Directors of the Company.

"CHANGE IN CONTROL" shall mean and include the following transactions or
situations:

     (a)  A sale, transfer, or other disposition by the Company through a
single transaction or a series of transactions of securities of the Company
representing 30 percent or more of the combined voting power of the
Company's then outstanding securities to any "Unrelated Person" or
"Unrelated Persons" acting in concert with one another.  For purposes of
this Section, the term "Person" shall mean and include any individual,
partnership, joint venture, association, trust corporation, or other entity
(including a "group" as referred to in Section 13(d)(3) of the Act). For

                                   13
<PAGE>
purposes of this Section, the term "Unrelated Person" shall mean and
include any Person other than the Company, a wholly-owned subsidiary of the
Company, or an employee benefit plan of the Company.

     (b)  A sale, transfer, or other disposition through a single
transaction or a series of transactions of all or substantially all of the
assets of the Company to an Unrelated Person or Unrelated Persons acting in
concert with one another.

     (c)  A change in the ownership of the Company through a single
transaction or a series of transactions such that any Unrelated Person or
Unrelated Persons acting in concert with one another become the "Beneficial
Owner," directly or indirectly, of securities of the Company representing
at least 30 percent of the combined, voting power of the Company's then
outstanding securities.  For purposes of this Section, the term "Beneficial
Owner" shall have the same meaning as given to that term in Rule 13d-3
promulgated under the Act, provided that any pledgee of voting securities
is not deemed to be the Beneficial Owner thereof prior to its acquisition
of voting rights with respect to such securities.

     (d)  Any consolidation or merger of the Company with or into an
Unrelated Person, unless immediately after the consolidation or merger the
holders of the common stock of the Company immediately prior to the
consolidation or merger are the Beneficial Owners of securities of the
surviving corporation representing at least 50 percent of the combined
voting power of the surviving corporation's then outstanding securities.

     (e)  During any period of two years, individuals who, at the beginning
of such period, constituted the Board of Directors of the Company cease,
for any reason, to constitute at least  a majority thereof, unless the
election or nomination for election of each new director was approved by
the vote of at least two-thirds of the directors then still in office who
were directors at the beginning of such period.

     (f)  A change in control of the Company of a nature that would be
required to be reported in response to Item 6(e) of Schedule l4A of
Regulation 14A promulgated under the Act, or any successor regulation of
similar import, regardless of whether the Company is subject to such
reporting requirement.

     Notwithstanding any provision hereof to the contrary, the filing of a
proceeding for the reorganization of the Company under Chapter 11 of the
General Bankruptcy Code or any successor or other statute of similar import
shall not be deemed to be a Change of Control for purposes of this Plan.

"CODE" shall mean the internal Revenue Code of 1986, as amended.

"COMMITTEE" shall mean the Compensation Committee appointed by the Board,
if one has been appointed.  If no Committee has been appointed, the term
"Committee" shall mean the Board.

"COMPANY" shall mean Entropin, Inc., a Colorado corporation.

                                   14
<PAGE>
"CORPORATE TRANSACTION" shall mean: (a) a merger or consolidation in which
the Company is not the surviving entity, except for a transaction the
principal purposes of which is to change the state in which the Company is
incorporated; (b) the sale, transfer of or other disposition of all or
substantially all of the assets of the Company and complete liquidation or
dissolution of the Company; or, (c) any reverse merger in which the Company
is the surviving entity hut in which the securities possessing more than 50
percent of the total combined voting power of the Company's outstanding
securities are transferred to a person or persons different from those who
held such securities immediately prior to such merger.

"EFFECTIVE DATE" shall mean the date that the Plan has been approved by the
Stockholders as required by SECTION 1 3(a) hereof.

"ELIGIBLE PERSONS" shall mean, with respect to the Plan, those persons who,
at the time that the Option or Award is granted, are (i) employees
(including officers and directors) of the Company or Parent or Subsidiary
Corporations, or (ii) consultants or independent contractors who provide
valuable services to The Company or Parent or Subsidiary Corporations.

"EXERCISE DATE" shall be the date on which written notice of the exercise
of an Option is delivered to the Company in accordance with the
requirements of the Plan.

"GRANTEE" shall mean an Eligible Person that has received an Award.

"INCENTIVE STOCK OPTION" shall mean a Option that is intended to qualify as
an "Incentive stock option" under Code section 422.

"NON-AFFILIATES" shall mean all persons who are not Affiliates.

"NON-EMPLOYEE DIRECTOR" shall have the same meaning as ascribed under Rule
16b-3(b)(3)(i) of the Securities Exchange Act of 1934, as amended.


"$100,000 LIMITATION" shall mean the limitation in which the aggregate fair
market value (determined as of the respective date or dates of grant) of
the Stock for which one or more Options granted to any person under this
Plan (or any other option plan of the Company or any Parent or Subsidiary
Corporation) may for the first time be exercisable as Incentive Stock
Options during any one calendar year shall not exceed the sum of $100,000.

"OPTIONHOLDER" shall mean an Eligible Person or Eligible Director to whom
Options have been granted.

"OPTIONED SHARES" shall be those shares of Stock to be optioned from time
to time to any Eligible Person or Directors.

                                   15
<PAGE>
"OPTION PRICE" shall mean the option price per share as specified by the
Committee or by the terms of the Plan.

"OPTIONS" shall mean options granted under the Plan to acquire Stock.

"PARENT" OR "PARENT Corporation" shall mean any corporation as defined in
Section 424(e) of the Code, with respect to the Corporation.

"PLAN" shall mean The 1998 Compensatory Stock Plan for the Company.

"SAR" shall mean stock appreciation rights granted pursuant to SECTION 2.4
hereof.

"SERVICE" shall have the meaning set forth in SECTION 2.2(n) hereof.

"STOCK" shall mean shares of the Company's Common Stock, $.00001 par value
per share, which may be unissued or treasury shares, as the Board may from
time to time determine.

"STOCK AWARDS" shall mean Stock directly granted under the Plan.

"SUBSIDIARY CORPORATION" shall mean any corporation in the unbroken chain
of corporations starting with the employer corporation, where, at each link
of the chain, the corporation and the link above owns at least 50 percent
of the combined voting power of all classes of stock in the corporation below.

EXECUTED as of the ___ day of __________, 1998.

                                        Entropin, Inc.



                                        By:   /s/ Higgins D. Bailey
                                             ---------------------------
                                        Name:  Higgins D. Bailey
                                             ---------------------------
                                        Its:    Chairman of the Board
                                             --------------------------






                                   16
<PAGE>
                             ENTROPIN, INC.                        [date]
__________________________________________________________________________
              PROXY FOR THE ANNUAL MEETING OF SHAREHOLDERS
                   SOLICITED BY THE BOARD OF DIRECTORS
__________________________________________________________________________
     The undersigned hereby appoints Higgins D. Bailey and Thomas G.
Tachovsky, and each of them, with full power of substitution to represent
the undersigned and to vote all of the shares of stock of Entropin, Inc.
(the "Company") which the undersigned is entitled to vote at the Annual
Meeting of Shareholders of the Company to be held at The Westin Tabor
Center, 1672 Lawrence Street, Denver, Co 80202 on Wednesday, June 14, 2000
at 8:00 A.M. Mountain Daylight Time, and at any adjournment thereof (i) as
hereinafter specified upon the proposal listed on the reverse side and as
more particularly described in the Company's Proxy Statement, receipt of
which is hereby acknowledged, and (ii) in their discretion upon such other
matters as may properly come before the meeting.

     THE SHARES REPRESENTED HEREBY SHALL BE VOTED AS SPECIFIED.  IF NO
SPECIFICATION IS MADE, SUCH SHARES SHALL BE VOTED IN FAVOR OF ALL PROPOSALS
CONTAINED IN THE PROXY STATEMENT.

     A vote FOR the following proposals is recommended by the Board of
Directors:

     1.   To authorize the Company's Board of Directors to amend the
          Articles of Incorporation to modify the lengths of the terms of
          the directors of the Company;

                    [   ] FOR [   ] AGAINST  [   ] ABSTAIN

     2.   To elect seven directors as proposed in the Proxy Statement to
          such terms as will be required by the Articles of Incorporation
          as may be amended by Proposal 1, above;

Thomas G. Tachovsky, Ph.D.         [   ] FOR [   ] AGAINST  [   ] ABSTAIN
Higgins D. Bailey, Ed.D.           [   ] FOR [   ] AGAINST  [   ] ABSTAIN
Donald Hunter                      [   ] FOR [   ] AGAINST  [   ] ABSTAIN
Daniel L. Azarnoff, M.D.           [   ] FOR [   ] AGAINST  [   ] ABSTAIN
James E. Wynn, Ph.D.               [   ] FOR [   ] AGAINST  [   ] ABSTAIN
Wilson Benjamin                    [   ] FOR [   ] AGAINST  [   ] ABSTAIN
Joseph R. Ianelli                  [   ] FOR [   ] AGAINST  [   ] ABSTAIN

     3.   To ratify the 1998 Compensatory Stock Plan and an amendment
          increasing the maximum aggregate number of shares reserved for
          issuance thereunder to 500,000 shares of Common Stock;

                    [   ] FOR [   ] AGAINST  [   ] ABSTAIN

     4.   To ratify the selection of Causey Demgen & Moore, Inc. as
          independent auditors of the Company for the year ending December 31,
          2000;

                    [   ] FOR [   ] AGAINST  [   ] ABSTAIN
               CONTINUED AND TO BE SIGNED ON REVERSE SIDE

<PAGE>
MARK HERE FOR ADDRESS CHANGE AND NOTE BELOW. [     ]

     ______________________________________
     ______________________________________
     ______________________________________
     ______________________________________

     Even if you are planning to attend the meeting in person, you are
urged to sign and mail the Proxy in the return envelope so that your stock
may be represented at the meeting.

DO YOU PLAN TO ATTEND THE ANNUAL MEETING:    [   ]   YES      [   ] NO

     Sign exactly as your name(s) appears on your stock certificate.  If
shares of stock stand on record in the names of two or more persons or in
the name of husband and wife, whether as joint tenants or otherwise, both
or all of such persons should sign the above Proxy.  If shares of stock are
held of record by a corporation, the Proxy should be executed by the
president or Vice President and the Secretary or Assistant Secretary, and
the corporate seal should be affixed thereto.  Executors or administrators
or other fiduciaries who execute the above Proxy for a deceased shareholder
should give their title.  Please date the Proxy.

Signature(s)   __________________________________ Date: ________________

               __________________________________ Date: ________________


© 2022 IncJournal is not affiliated with or endorsed by the U.S. Securities and Exchange Commission