APHTON CORP
DEF 14A, 1997-08-27
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                               September 23, 1997



Dear Shareholder:

     The Annual Meeting of  Shareholders of Aphton  Corporation  will be held on
Wednesday,  October  22,  1997,  at 9:00 A.M.  at the  offices  of White & Case,
located at First Union Financial Center,  200 South Biscayne  Boulevard,  Miami,
Florida 33131-2352.

     The Notice of Annual Meeting and the Proxy Statement are enclosed herewith.
Shareholders will be asked to elect four directors.  The four current directors,
Philip C. Gevas, Nicholas J. Stathis, Robert S. Basso and William A. Hasler, are
nominees for election.  Your Board of Directors  recommends  that you vote "for"
these proposals.

     Please review the Proxy  Statement and at your earliest  convenience  sign,
date and return the enclosed  proxy card so that your shares will be represented
at the meeting. A prepaid return envelope is enclosed for this purpose.

Yours truly,
/s/ Philip C. Gevas
Philip C. Gevas
Chairman, President and Chief Executive Officer

PCG/ma
encl.










                               September 23, 1997

                    NOTICE OF ANNUAL MEETING OF SHAREHOLDERS

                                October 22, 1997

     The Annual  Meeting of  Shareholders  of Aphton  Corporation,  a California
corporation, will be held at the offices of White & Case, located at First Union
Financial Center, 200 South Biscayne Boulevard,  Miami, Florida 33131-2352.,  on
Wednesday, October 22, 1997, at 9:00 A.M. for the following purposes:

     (1) To elect  directors  to hold office  until the next  Annual  Meeting of
Shareholders  and  thereafter  until  their  successors  are  duly  elected  and
qualified;

     (2) To  transact  such  other  business  as may  properly  come  before the
meeting.

     On any  business day from  October 8, 1997 until  October 21, 1997,  during
ordinary  business hours,  shareholders may examine the list of shareholders for
any  purpose  germane to the meeting at the Office of the  Company's  attorneys,
White & Case, First Union Financial Center, 200 South Biscayne Boulevard, Miami,
Florida 33131.

     The  Board of  Directors  has  fixed  the  close of  business  on  Tuesday,
September 9, 1997, as the record date for determination of shareholders entitled
to be notified and to vote at the Annual Meeting.

     ALL  STOCKHOLDERS  ARE CORDIALLY  INVITED TO ATTEND THE ANNUAL MEETING.  TO
ENSURE YOUR  REPRESENTATION  AT THE MEETING,  THE BOARD  REQUESTS THAT YOU SIGN,
DATE AND RETURN THE ENCLOSED PROXY IN THE ACCOMPANYING  SELF-ADDRESSED,  STAMPED
ENVELOPE. YOUR PROXY WILL NOT BE USED IF YOU ARE PRESENT AT THE MEETING AND WISH
TO VOTE YOUR SHARES PERSONALLY.

By Order of the Board of  Directors


/s/Philip C. Gevas
Philip C. Gevas
Chairman, President and
Chief Executive Officer










                                 PROXY STATEMENT

                         ANNUAL MEETING OF SHAREHOLDERS
                              OF APHTON CORPORATION

                                October 22, 1997

                              ---------------------

                                  INTRODUCTION

     This Proxy  Statement  is being mailed on or about  September  9, 1997,  to
shareholders  of Aphton  Corporation  (the  "Company")  in  connection  with the
solicitation  of  Proxies by the  Company's  Board of  Directors  for use at the
Company's Annual Meeting of Shareholders to be held on October 22, 1997, for the
purposes set forth herein and in the  accompanying  Notice of Annual  Meeting of
Shareholders.   The  accompanying  proxy,  and  all  expenses  incident  to  the
solicitation, are to be paid by the Company.

     The persons named in the  accompanying  proxy have advised the Company that
they intend to vote the proxies received by them in their discretion for as many
director nominees as the votes represented by such proxies are entitled to elect
(see "Election of  Directors").  Any  shareholder may revoke his or her proxy at
any time prior to its use by filing with the  Secretary of the Company a written
notice of revocation or a duly executed proxy bearing a later date.

     Only shareholders of record at the close of business on Tuesday,  September
9,  1997,  will be  entitled  to  notice  of and to vote at the  meeting  or any
adjournments  thereof.  At such record  date,  the Company had  outstanding  and
entitled to vote approximately  13,665,000 shares of common stock. Each share of
stock is  entitled  to one  vote on all  matters  other  than  the  election  of
directors.  In connection  with the election of directors,  each  shareholder is
entitled  to  cumulate  his or her  votes.  Reference  is made to  "Election  of
Directors."
                              ELECTION OF DIRECTORS

     In voting for directors of the Company,  each  shareholder has the right to
cumulate his or her votes and give one  candidate a number of votes equal to the
number of  directors to be elected,  multiplied  by the number of votes to which
his or her shares are entitled,  or to  distribute  his or her votes on the same
principle  among as many  candidates as he or she shall see fit. The  candidates
receiving  the  highest  number of votes,  up to the number of  directors  to be
elected,  shall be elected.  For a  shareholder  to exercise  cumulative  voting
rights,  such  shareholder  must give notice of his or her intention to cumulate
his or her votes at the meeting prior to the voting.

     The Company's Board of Directors presently consists of four directors.  The
persons who are elected directors will hold office until the next Annual Meeting
of  Shareholders  and thereafter  until their  successors are duly elected,  and
qualified.









     Set forth below are the names and  principal  occupations  of those persons
who are nominees for election as directors,  all of whom are presently directors
of the  Company,  and the  respective  number of  shares of voting  stock of the
Company beneficially owned, directly or indirectly, by them and by all directors
and officers as a group as of July 31, 1997, according to information  furnished
to the Company by such persons.

                               Shares Beneficially
      Name and Principal                Year First    Owned as of    Percent
           Occupation             Age    Elected     July 31, 1996   of Class
Philip C. Gevas                   64      1981        1,979,050(1)     14.5
Chairman, President and
Chief Executive Officer
Aphton Corporation

Robert S. Basso, President        52      1988           30,166         (2)
Correspondent Services
Corporation.

William A.  Hasler,  Dean of the  55      1991           35,000         (2)
Graduate    and    Undergraduate
Schools of Business,  University
of California, Berkeley

Nicholas John Stathis             73      1994           48,466         (2)
Attorney

All Directors and Officers
as a group (6 persons)                                2,202,882        16.2


- ----------------------------
(1) Includes  120,000  shares in a trust of which Mr. Gevas is an  uncompensated
trustee with no pecuniary interest in the trust assets.
(2)  Less than 1% of total outstanding shares.

     Mr.  Gevas has served the  Company in his current  capacity  and has been a
director of the Company  since its  inception.  Mr. Basso has been a director of
the Company since February, 1988. He has been employed in his present capacities
with Correspondent  Services Corporation since January, 1990. Prior thereto, for
more than ten years,  Mr. Basso was employed by Merrill  Lynch as President of a
wholly-owned subsidiary and in other executive management capacities. William A.
Hasler was elected Vice Chairman in October, 1996 and has been a director of the
Company  since  October,  1991.  Mr. Hasler is the Dean of both the Graduate and
Undergraduate  Schools of Business at the  University of  California,  Berkeley.
Dean Hasler was formerly  Vice Chairman of KPMG Peat  Marwick,  responsible  for
management  consulting.  Dean  Hasler is a  director  of The Gap,  Inc.,  Walker
Interactive  Systems,  TCSI Corporation and Tenera,  Inc. Nicholas John Stathis,
Esq. has been a director of the Company  since  January,  1994.  Mr.  Stathis is
retired from the law firm of White & Case,  where he was of counsel from 1989 to
1993.  Prior to that he was partner,  Botein,  Hays & Sklar,  from 1984 to 1989.

Directors do not receive any fees for services on the Board.  Board  members are
reimbursed for their expenses for each meeting attended.

If for  any  reason  one or more  of the  nominees  named  above  should  not be
available as a candidate for director, an event that the Board of Directors does
not anticipate, the persons named in the enclosed proxy will vote for such other
candidate  or  candidates  as may be  nominated  by the Board and  discretionary
authority to do so is included in the Proxy.  Committee Meetings of the Board of
Directors

                        Committee Meetings of the Board

The Company's  Board of Directors  held four general  meetings and six committee
meetings during fiscal 1997. The Board of Directors has two standing committees:
an Audit Committee,  consisting of Messrs.  Hasler  (Chairman),  Basso and Gevas
(non-voting);  and  a  Compensation  Committee,   consisting  of  Messrs.  Basso
(Chairman) and Hasler.  The Audit Committee reviews the financial  statements of
the  Company,   reviews  the  independent   accountants'  scope  of  engagement,
performance  and  fees  and  reviews  the  adequacy  of the  Company's  internal
financial  control  procedures.  This Committee held two meetings  during fiscal
1997.  The   Compensation   Committee   reviews  and   recommends   remuneration
arrangements for various key executives.  This Committee held one meeting during
fiscal 1997. Each Committee member attended all of the meetings of the Committee
on which he was a member during fiscal 1997.

                        The Compensation Committee Report

The Compensation Committee of the Board approves compensation objectives, policy
and compensation for the Company's executive officers, including the individuals
named in the Summary Compensation table below.

The Compensation Committee is comprised of Messrs. Basso and Hasler who are
independent outside directors.

The Compensation  Committee seeks to provide rewards which are closely linked to
Company and individual  performance  and ensure that  compensation is at a level
which  enables the Company to attract and retain the high  quality  employees it
needs. In addition,  the committee  considers  performance factors particular to
each  executive  officer,  such  as  the  performance  where  such  officer  had
responsibility and individual managerial accomplishments.

Compensation of the Chief Executive Officer The Compensation  Committee believes
that Mr.  Gevas' total  compensation  as Chief  Executive  Officer  reflects his
performance in meeting the goals  established  by the Committee.  In determining
Mr.  Gevas'  total  compensation,  the  Compensation  Committee  considered  the
Company's  overall  performance  and Mr. Gevas'  individual  performance  by the
measures described above for determining  executive officers'  compensation.  It
also considered the compensation and company  performance of the chief executive
officers  of  other  leading  companies,   as  well  as  incentives  for  future
performance.

The    Company's    performance    as   measured   in   the   context   of   the
biotechnology/biopharmaceutical  industry and Mr. Gevas' contributions  thereto,
both  management  and  scientific,   have  met  the  Company  objectives.   This
performance  included  the  structuring,   negotiation,  and  execution  of  the
strategic  alliance  agreement  with Pasteur  Merieux  Connaught  (Rhone-Poulenc
Group).  The following stock price  performance graph is provided as required by
the  Securities  and Exchange  Commission.  The graph begins April 30, 1992. The
graph  compares  the  Company's  stock price  appreciation  with the stock price
appreciation   of  both  the  Nasdaq   Composite  Index  and  a  peer  group  of
biotechnology/  biopharmaceutical  companies which, like Aphton,  had an initial
public offering (IPO) during 1991.

The foregoing report has been furnished by the Compensation Committee consisting
of Messrs. Hasler and Basso (Chairman).





                          Stock Price Performance Graph

The following graph illustrates a comparison of the cumulative total stockholder
return  (change in stock  price) of  Aphton's  Common  Stock with the CRSP Total
Return Index for the Nasdaq Stock Market (the Nasdaq Composite Index) and a Peer
Group composed of other biotechnology/biopharmaceutical companies which had IPOs
during the same year as Aphton (and are still  publicly  traded).  The following
graph commences as of April 30,1992,  with a $100 investment in the Company, the
Nasdaq index and the Peer Group (whose  composition  reflects the average of the
share values as reported on the dates shown).  Graphic  comparisons are required
by the Securities and Exchange Commission (SEC) and are not intended to forecast
or be indicative of possible future performances of the Company's Common Stock.

Aphton believes that the best date for Aphton  shareholders to begin comparisons
is the first date of trading in the Company's  stock.  Aphton also believes that
the  best   peer   group  for   graphic   comparisons   is  the   biotechnology/
biopharmaceutical  companies  which,  like  Aphton,  had IPOs  during  1991 (the
initial date of investments of $100).  However,  Aphton is not aware of any such
published  "third-party" index or listing;  thus, the Peer Group names and graph
was prepared by the Company based on data provided to Aphton by Nasdaq. The Peer
Group is  composed of Cygnus  Therapeutic  Systems,  Regeneron  Pharmaceuticals,
Cephalon Inc.,  Medimmune  Inc.,  Isis,  ImmuLogic  Pharmaceutical,  ICOS Corp.,
Cambridge  NeuroScience,   Genelabs  Technologies,  COR  Therapeutics,  Curative
Technologies,  Alkermes,  Osteotech,  Vertex,  Genetic Therapy,  Somatogen Inc.,
Biomatrix,  IDEC  Pharmaceuticals,  Sepracor Inc.,  CellPro Inc.,  Anergen Inc.,
Alteon Inc., ImClone Systems,  Cytel, Magainin  Pharmaceuticals and Genta. Other
biotechnology/biopharmaceutical  companies  which  had  IPOs  in  1991  are  not
included here if they no longer exist or are no longer publicly traded.

                         4/30/92 4/30/93 4/30/94 4/29/95 4/28/96 4/30/97
Aphton Corporation         100     83     106      81     120      88
All US & Foreign on NASDAQ 100    114     127     145     212     223
Biotech Peer Group         100     76      63      56     112      85


                             Executive Compensation
The  following  table sets forth,  for each of the last five fiscal  years,  the
annual  compensation  paid by the Company,  together  with  long-term  and other
compensation,  for the Chief Executive Officer and the other highest compensated
Executive Officers of the Company in all capacities in which they served.
<TABLE>

                                                Summary Compensation Table
                                     Annual Compensation                  Long-Term Compensation
                                -------------------------------    --------------------------------------
                                                                        Awards              Payouts
                                                                 ---------------------     -----------
                                                      Other                                Long-Term
                       Fiscal                         Annual     Restricted                Incentive   All Other
    Name, Age and      Year                           Compen-sation Stock      Options/    Plan         Compen-
 Principal Position      End    Salary($)  Bonus($)      ($)     Award(s)($)    SARs(#)    Payouts($)  sation ($)
                         ---    ---------  --------      ---     -----------    -------    ----------  ----------
- ----------------------
<S>                    <C>      <C>        <C>          <C>        <C>        <C>           <C>         <C>          
Philip C. Gevas (63)   1997     200,000    200,000        -           -            -           -           -
Chief Executive        1996     200,000    200,000        -           -            -           -           -
Officer, President     1995     200,000    200,000        -           -            -           -           -
and Chief Financial    1994     180,000    200,000        -           -       400,000          -           -
Officer                1993     172,500    120,000        -           -            -           -           -

Dov Michaeli, M.D.,    1997     150,000      60,000       -           -            -           -           -
Ph.D. (61) Senior      1996     150,000      60,000       -           -            -           -           -
Vice President,        1995     150,000      60,000       -           -            -           -           -
Director of Medical    1994     110,000      60,000       -           -       150,000          -           -
Science                1993     110,000      30,000       -           -            -           -           -

Richard Ascione,       1997     125,000      25,000       -           -            -           -           -
Ph.D.(60) Vice         1996     125,000      25,000       -           -            -           -           -
President, Director    1995     112,500      25,000       -           -            -           -           -
of Laboratory of       1994         -          -          -           -        50,000          -           -
Molecular Medicine

Paul Broome, MB.,      1997     135,000      30,000       -           -            -           -           -
Ch.B., MFPM (46)       1996     132,300      26,450       -           -            -           -           -
Vice President and     1995     112,500      25,000       -           -            -           -           -
Medical Director,      1994         -          -          -           -        50,000          -           -
Clinical Trials and
Regulatory Affairs
</TABLE>


                        Option Grants in Last Fiscal Year
No options or stock  appreciation  rights  were  granted  during the fiscal year
ended April 30, 1997.

                   Option Exercises and Fiscal Year-End Values
The following table sets forth  information  concerning the unexercised  options
held as of the end of the fiscal year. No officers  exercised options during the
fiscal year.
<TABLE>

                  Option/SAR Exercises and Year-End Value Table
                  Aggregated Option/SAR Exercises in Last Fiscal Year, and FY-End Option/SAR Value
                                                                                            Value of Unexercised
                                                          Number of Unexercised             In-the-Money Options/
                                                                 Options/                   SARs at FY-End($)(1)
                                                            SARs at FY-End(#)
                                                       -----------------------------
                               Shares
                              Acquired       Value
         Name                    on       Realized($)   Exercisable   Unexercisable      Exercisable  Unexercisable
                             Exercise(#)
- -----------------------
<S>                          <C>            <C>          <C>           <C>                <C>          <C>              
Philip C. Gevas                   -            -          600,000           -                 -             -

- -----------------------
Dov Michaeli, M.D.,
Ph.D.                             -            -          370,000           -             1,375,000         -

- -----------------------
Richard Ascione, Ph.D.            -            -             -           50,000               -             -

- -----------------------
Paul Broome, MB.,
Ch.B., MFPM                       -            -             -           50,000               -              -
<FN>

(1)  Market value of shares covered by  in-the-money  options on April 30, 1997,
     less option exercise price. Options are in-the-money if the market value of
     the shares covered thereby is greater than the option  exercise price.  The
     market value is the closing price at April 30, 1997, as quoted by Nasdaq.
</FN>
</TABLE>


<PAGE>





                Long-Term Incentive Plans - Awards in Fiscal Year

No long-term  incentive  plan awards were  granted  during the fiscal year ended
1997.

                             Principal Shareholders

To  the  Company's  knowledge,   except  as  hereinafter  described,  no  single
shareholder of record owned or  beneficially  owned,  as of July 31, 1997,  more
than 5% of the  Company's  common  stock.  As of July 31,  1997,  Cede & Co.,  a
nominee  of  securities  depositories  for  various  segments  of the  financial
industry, held approximately 6,100,000 shares, representing approximately 45% of
the Company's  outstanding common stock, none of which was owned beneficially by
Cede & Co. The Company  believes that each of the entities or individuals  named
below  beneficially  owns 5% or more of the Company's  common stock,  based on a
review of filings made with the SEC.

         Name and Address of
           Beneficial Owner           Number of Shares     % of Common Stock

Smith Barney  Mutual Funds  Management,  1,481,900               10.9
Inc
388 Greenwich Street
Legal Dept, 20th Floor
New York, New York 10013

Eliezer Benjamini, Ph.D.                   731,500                5.4
P. O. Box 1049
Woodland, CA 95776

Joy Benjamini                              731,500                5.4
P. O. Box 1049
Woodland, CA 95776

Philip C. Gevas                          1,979,050               14.5
P. O. Box 1049                             (1)
Woodland, CA 95776

Richard L. Littenberg, M.D.              1,246,250                9.1
P. O. Box 1049
Woodland, CA 95776

Robert J. Scibienski, Ph.D.              1,613,800               11.8
P. O. Box 1049
Woodland, CA 95776

All Executive Officers and               2,202,882               16.2
Directors as a group (6 persons)
- ----------------------------
(1)  Includes  120,000 shares in a trust of which Mr. Gevas is an  uncompensated
     trustee with no pecuniary interest in the trust assets.



                              Shareholder Proposals

If a shareholder intends to have a proposal presented at the next Annual Meeting
of  Shareholders,  such a  proposal  must  be  received  by the  Company  at its
principal executive offices prior to the end of fiscal year 1998.





                                  Miscellaneous

Coopers & Lybrand has been the Company's independent accountants for a number of
years and has been selected to continue in such capacity for the current  fiscal
year. It is  anticipated  that a  representative  from Coopers & Lybrand will be
available to answer  questions  raised at the Annual Meeting of Shareholders and
will be afforded the opportunity to make any statements the  representative  may
desire to make.

The Board of Directors  knows of no other matters that are likely to come before
the  meeting.  If any such  matters  should  properly  come before the  meeting,
however, it is intended that the persons named in the accompanying form of proxy
will vote such proxy in accordance with their best judgment on such matters.

By Order of the Board of Directors



/s/Philip C. Gevas
Philip C. Gevas
Chairman and Secretary


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