APHTON CORP
DEF 14A, 1998-06-01
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                                                   July 1, 1998



Dear Shareholder:

The  Annual  Meeting  of  Shareholders  of  Aphton  Corporation  will be held on
Wednesday,  July 29, 1998, at 9:00 A.M. at the offices of White & Case,  located
at First Union Financial Center, 200 South Biscayne Boulevard, Miami, Florida
33131-2352.

The Notice of Annual  Meeting and the Proxy  Statement  are  enclosed  herewith.
Shareholders  will be asked to elect four directors in three  classes.  The four
current  directors,  Philip C. Gevas,  Nicholas J. Stathis,  Robert S. Basso and
William A. Hasler,  are nominees for election.  The Class 1 nominee is Robert S.
Basso  whose  term  of  office  would  expire  at the  1999  Annual  Meeting  of
Shareholders.  The Class 2 nominee is Nicholas J.  Stathis  whose term of office
would expire at the 2000 Annual  Meeting of  Shareholders.  The Class 3 nominees
are Philip C. Gevas and William A. Hasler  whose term of office  would expire at
the 2001 Annual Meeting of Shareholders. Your Board of Directors recommends that
you vote "for" these nominees.

Please review the Proxy  Statement and at your earliest  convenience  sign, date
and return the enclosed  proxy card so that your shares will be  represented  at
the meeting. A prepaid return envelope is enclosed for this purpose.

Yours truly,
- ----/s/------
Philip C. Gevas
Chairman, President and Chief Executive Officer

PCG/ma
encl.

<PAGE>









                                  July 1, 1998

                    NOTICE OF ANNUAL MEETING OF SHAREHOLDERS

                                  July 29, 1998

The  Annual  Meeting  of   Shareholders  of  Aphton   Corporation,   a  Delaware
corporation, will be held at the offices of White & Case, located at First Union
Financial Center, 200 South Biscayne Boulevard,  Miami, Florida 33131-2352.,  on
Wednesday, July 29, 1998, at 9:00 A.M. for the following purposes:

(1)  To elect four  directors  in three  classes to hold office  until the 1999,
     2000 or 2001 Annual  Meeting of  Shareholders  and  thereafter  until their
     successors are duly elected and qualified;

(2)  To transact such other business as may properly come before the meeting.

On any  business  day from July 15, 1998 until July 28,  1998,  during  ordinary
business  hours,  shareholders  may  examine  the list of  shareholders  for any
purpose germane to the meeting at the Office of the Company's attorneys, White &
Case, First Union Financial Center, 200 South Biscayne Boulevard, Miami, Florida
33131.

The Board of Directors  has fixed the close of business on  Wednesday,  June 17,
1998,  as the record  date for  determination  of  shareholders  entitled  to be
notified and to vote at the Annual Meeting.

ALL STOCKHOLDERS ARE CORDIALLY  INVITED TO ATTEND THE ANNUAL MEETING.  TO ENSURE
YOUR  REPRESENTATION AT THE MEETING,  THE BOARD REQUESTS THAT YOU SIGN, DATE AND
RETURN THE ENCLOSED PROXY IN THE ACCOMPANYING SELF-ADDRESSED,  STAMPED ENVELOPE.
YOUR PROXY WILL NOT BE USED IF YOU ARE  PRESENT AT THE  MEETING AND WISH TO VOTE
YOUR SHARES PERSONALLY.

By Order of the Board of Directors
- ------/s/------
Philip C. Gevas
Chairman, President and
Chief Executive Officer

<PAGE>










                                 PROXY STATEMENT

                         ANNUAL MEETING OF SHAREHOLDERS
                              OF APHTON CORPORATION

                                  July 29, 1998

                              _____________________

                                  INTRODUCTION

This Proxy  Statement is being mailed on or about July 1, 1998, to  shareholders
of Aphton  Corporation  (the "Company") in connection  with the  solicitation of
Proxies by the  Company's  Board of Directors  for use at the  Company's  Annual
Meeting of  Shareholders to be held on July 29, 1998, for the purposes set forth
herein and in the  accompanying  Notice of Annual Meeting of  Shareholders.  The
accompanying  proxy, and all expenses  incident to the  solicitation,  are to be
paid by the Company.

The persons named in the  accompanying  proxy have advised the Company that they
intend to vote the  proxies  received  by them in their  discretion  for as many
director nominees as the votes represented by such proxies are entitled to elect
(see "Election of  Directors").  Any  shareholder may revoke his or her proxy at
any time prior to its use by filing with the  Secretary of the Company a written
notice of revocation or a duly executed proxy bearing a later date.

Only  shareholders  of record at the close of  business on  Wednesday,  June 17,
1998,  will  be  entitled  to  notice  of and to  vote  at  the  meeting  or any
adjournments  thereof.  At such record  date,  the Company had  outstanding  and
entitled to vote approximately  14,200,000 shares of common stock. Each share of
stock is entitled to one vote on all matters.

                              ELECTION OF DIRECTORS

The  Company's  Board of Directors  presently  consists of four  directors.  The
persons who are elected  directors will hold office until the 1999, 2000 or 2001
Annual Meeting of Shareholders  and thereafter  until their  successors are duly
elected, and qualified.

Set forth below are the names and principal occupations of those persons who are
nominees for election as directors,  all of whom are presently  directors of the
Company,  and the  respective  number of shares of voting  stock of the  Company
beneficially  owned,  directly or  indirectly,  by them and by all directors and
officers as a group as of May 31, 1998,  according to  information  furnished to
the Company by such persons.


                                              Shares Beneficially
      Name and Principal              Year First  Owned as of
           Occupation            Age   Elected    May 31, 1998 Percent of Class

Philip C. Gevas                   65      1981    1,949,050(1)         13.7
Chairman, President and
Chief Executive Officer
Aphton Corporation

William A.  Hasler                56      1991      35,000              (2)
Co-Chief Executive Officer
and Vice-Chairman
Aphton Corporation

Robert S. Basso, President        53      1988      30,166              (2)
Correspondent Services
Corporation.
Nicholas John Stathis             74      1994      50,000              (2)
Attorney

All Directors and Officers
as a group (7 persons)                           2,176,416             15.3


____________________________
(1)  Includes  90,000  shares in a trust of which Mr. Gevas is an  uncompensated
     trustee with no pecuniary interest in the trust assets.

(2)  Less than 1% of total outstanding shares.

Mr.  Gevas has served the Company and  continues to serve in the  capacities  of
Chairman,  President and Chief Executive  Officer and has been a director of the
Company  since its  inception.  William A. Hasler was elected  Vice  Chairman in
October,  1996 and has been a director of the Company since  October,  1991. Mr.
Hasler was the Dean of both the Graduate and  Undergraduate  Schools of Business
at the University of California,  Berkeley until July 1, 1998 when he became the
Co-Chief Executive Officer of Aphton Corporation.  Dean Hasler was formerly Vice
Chairman of KPMG Peat Marwick,  responsible for management consulting worldwide.
Dean Hasler is a director of Solectron Corporation,  Walker Interactive Systems,
TCSI Corporation,  Tenera,  Inc. and is Public Governor of the Pacific Exchange.
Mr. Basso has been a director of the Company since  February,  1988. He has been
employed in his present capacities with Correspondent Services Corporation since
January, 1990. Prior thereto, for more than ten years, Mr. Basso was employed by
Merrill Lynch as President of a wholly-owned  subsidiary and in other  executive
management  capacities.  Nicholas John Stathis,  Esq. has been a director of the
Company since January, 1994. Mr. Stathis is retired from the law firm of White &
Case,  where he was of counsel from 1989 to 1993.  Prior to that he was partner,
Botein, Hays & Sklar, from 1984 to 1989.

Directors do not receive any fees for services on the Board.  Board  members are
reimbursed for their expenses for each meeting attended.

If for  any  reason  one or more  of the  nominees  named  above  should  not be
available as a candidate for director, an event that the Board of Directors does
not anticipate, the persons named in the enclosed proxy will vote for such other
candidate  or  candidates  as may be  nominated  by the Board and  discretionary
authority to do so is included in the Proxy.











                  Committee Meetings of the Board of Directors

The Company's  Board of Directors  held five general  meetings and two committee
meetings  during the nine months ended January 31, 1998.  The Board of Directors
has two standing committees:  an Audit Committee,  consisting of Messrs.  Hasler
(Chairman),  Basso  and  Gevas  (non-voting);   and  a  Compensation  Committee,
consisting of Messrs.  Basso (Chairman) and Hasler.  The Audit Committee reviews
the financial  statements of the Company,  reviews the independent  accountants'
scope of  engagement,  performance  and fees and  reviews  the  adequacy  of the
Company's  internal  financial  control  procedures.  This  Committee  held  one
meetings during fiscal 1998. The Compensation  Committee  reviews and recommends
remuneration  arrangements  for various key executives.  This Committee held one
meeting during fiscal 1998.  Each Committee  member attended all of the meetings
of the Committee on which he was a member during fiscal 1998.

                        The Compensation Committee Report

The Compensation Committee of the Board approves compensation objectives, policy
and compensation for the Company's executive officers, including the individuals
named in the Summary Compensation table below.

The  Compensation  Committee is  comprised  of Messrs.  Basso and Hasler.

The Compensation  Committee seeks to provide rewards which are closely linked to
Company and individual  performance  and ensure that  compensation is at a level
which  enables the Company to attract and retain the high  quality  employees it
needs. In addition,  the committee  considers  performance factors particular to
each  executive  officer,  such  as  the  performance  where  such  officer  had
responsibility and individual managerial accomplishments.

Compensation of the Chief Executive Officer

The Compensation  Committee believes that Mr. Gevas' total compensation as Chief
Executive  Officer  reflects his  performance  in meeting or exceeding the goals
established by the Committee.

In  determining  Mr.  Gevas'  total  compensation,  the  Compensation  Committee
considered  the  Company's   overall   performance  and  Mr.  Gevas'  individual
performance by the measures described above for determining  executive officers'
compensation. It also considered the compensation and company performance of the
chief executive officers of other leading  companies,  as well as incentives for
future performance.

The    Company's    performance    as   measured   in   the   context   of   the
biotechnology/biopharmaceutical  industry and Mr. Gevas' contributions  thereto,
both  management and  scientific,  have met or exceeded the Company  objectives.
This   performance   included  the  structuring  and  negotiation  with  another
significant pharmaceutical company for a strategic alliance. The following stock
price  performance  graph is provided as required by the Securities and Exchange
Commission.  The graph compares the Company's stock price  appreciation with the
stock price  appreciation of both the Nasdaq Composite Index and a peer group of
biotechnology/  biopharmaceutical  companies which, like Aphton,  had an initial
public offering (IPO) during 1991, and includes the measurement point as defined
and required by the SEC.

The foregoing report has been furnished by the Compensation Committee consisting
of Messrs. Hasler and Basso (Chairman).

                          Stock Price Performance Graph

The following graph illustrates a comparison of the cumulative total stockholder
return  (change in stock  price) of  Aphton's  Common  Stock with the CRSP Total
Return Index for the Nasdaq Stock Market (the Nasdaq Composite Index) and a Peer
Group composed of other biotechnology/biopharmaceutical companies which had IPOs
during the same year as Aphton (and are still  publicly  traded).  The following
graph commences in 1991, with a $100 investment in the Company, the Nasdaq index
and the Peer Group (whose  composition  reflects the average of the share values
as reported on the dates shown).  Five year graphic  comparisons are required by
the  Securities  and  Exchange   Commission  (SEC).  An  additional   comparison
commencing with a $100 investment in the Company,  the Nasdaq index and the Peer
Group at the required  measurement  date of January 31, 1993 is included.  These
graphs  are not  intended  to  forecast  or be  indicative  of  possible  future
performances of the Company's Common Stock.

Aphton believes that the best date for Aphton  shareholders to begin comparisons
is the first date of trading in the Company's  stock.  Aphton also believes that
the  best   peer   group  for   graphic   comparisons   is  the   biotechnology/
biopharmaceutical  companies  which,  like  Aphton,  had IPOs  during  1991 (the
initial date of investments of $100).  However,  Aphton is not aware of any such
published  "third-party" index or listing;  thus, the Peer Group names and graph
was prepared by the Company based on data provided to Aphton by Nasdaq. The Peer
Group is  composed of Cygnus  Therapeutic  Systems,  Regeneron  Pharmaceuticals,
Cephalon Inc.,  Medimmune  Inc.,  Isis,  ImmuLogic  Pharmaceutical,  ICOS Corp.,
Cambridge  NeuroScience,   Genelabs  Technologies,  COR  Therapeutics,  Curative
Technologies,  Alkermes,  Osteotech,  Vertex,  Genetic Therapy,  Somatogen Inc.,
Biomatrix,  IDEC  Pharmaceuticals,  Sepracor Inc.,  CellPro Inc.,  Anergen Inc.,
Alteon Inc., ImClone Systems,  Cytel, Magainin  Pharmaceuticals and Genta. Other
biotechnology/biopharmaceutical  companies  which  had  IPOs  in  1991  are  not
included here if they no longer exist or are no longer publicly traded.

                           1991  1/31  1/29  1/31  1/31  1/31  1/31  1/30  5/29
         Period from IPO   IPO   1992  1993  1994  1995  1996  1997  1998  1998
Aphton Corporation         100    304   220   350   139   146   318   177   200
All US & Foreign on NASDAQ 100    131   147   171   161   227   296   348   403
Biotech Peer Group         100    160   136   118    63   133   128   139   143

                                       1/29  1/31  1/31  1/31  1/31  1/30  5/29
     Five years ended 1/31/98          1993  1994  1995  1996  1997  1998  1998
Aphton Corporation                      100   159    63    67   146    80    80
All US & Foreign on NASDAQ              100   116   109   154   201   236   274
Biotech Peer Group                      100    87    47    98    94   102   102


                             Executive Compensation

The  following  table sets forth,  for each of the last five fiscal  years,  the
annual  compensation  paid by the Company,  together  with  long-term  and other
compensation,  for the Chief Executive Officer and the other highest compensated
Executive Officers of the Company in all capacities in which they served.
<TABLE>

                                                Summary Compensation Table
                                     Annual Compensation                  Long-Term Compensation
                                -------------------------------    --------------------------------------
                                                                        Awards              Payouts
                                                                 ---------------------     -----------

                 
                                                      Other                                Long-Term
                       Fiscal                         Annual        Restricted             Incentive   All Other
    Name, Age and      Period                         Compensation   Stock        Options/  Plan       Compen-
 Principal Position    End       Salary($) Bonus($)  ($) Award(s)      ($)         SARs(#)  Payouts($) sation ($)
       <C>                <C>      <C>      <C>         <C>            <C>          <C>      <C>         <C>
- ----------------------
Philip C. Gevas (65)     *1998  150,000    200,000        -           -            -           -           -
Chief Executive           1997  200,000    200,000        -           -            -           -           -
Officer, President        1996  200,000    200,000        -           -            -           -           -
and Chief Financial       1995  180,000    200,000        -           -            -           -           -
Officer                   1994  172,500    120,000        -           -       400,000          -           -
                                            
Dov Michaeli, M.D.,      *1998  112,500      60,000       -           -            -           -           -
Ph.D. (61) Senior         1997  150,000      60,000       -           -            -           -           -
Vice President,           1996  150,000      60,000       -           -            -           -           -
Director of Medical       1995  150,000      60,000       -           -            -           -           -
Science                   1994  110,000      30,000       -           -       150,000          -           -

Richard Ascione,         *1998    87,500     25,000       -           -            -           -           -
Ph.D.(60) Vice            1997  125,000      25,000       -           -            -           -           -
President, Director       1996  125,000      25,000       -           -            -           -           -
of Laboratory of          1995  112,500      25,000       -           -            -           -           -
Molecular Medicine        1994      -          -                               50,000

Paul Broome, MB.,        *1998    93,750     30,000       -           -            -           -           -
Ch.B., MFPM (46)          1997  135,000      30,000       -           -            -           -           -
Vice President and        1996  132,300      26,450       -           -            -           -           -
Medical Director,         1995  112,500      25,000       -           -            -           -           -
Clinical Trials and       1994      -          -          -           -        50,000          -           -
Regulatory Affairs
________________________________________
*Nine month fiscal period ended January 31, 1998
</TABLE>

                        Option Grants in Last Fiscal Year
No options or stock  appreciation  rights  were  granted  during the nine months
ended January 31, 1998.

                   Option Exercises and Fiscal Year-End Values
The following table sets forth  information  concerning the unexercised  options
held as of the end of the fiscal year. No officers  exercised options during the
fiscal year.

<TABLE>

                  Option/SAR Exercises and Year-End Value Table
 Aggregated Option/SAR Exercises in Last Fiscal Year, and FY-End Option/SAR Value
                                                                                            Value of Unexercised
                                                          Number of Unexercised             In-the-Money Options/
                               Shares                            Options/                   SARs at FY-End($)(1)
                                                            SARs at FY-End(#)
                                                       -----------------------------
                              Acquired       Value
         Name                    on       Realized($)   Exercisable   Unexercisable      Exercisable  Unexercisable
                             Exercise(#)
          <C>                   <C>         <C>            <C>             <C>               <C>          <C>                
- -----------------------
Philip C. Gevas                   -            -          600,000           -                 -             -

- -----------------------
Dov Michaeli, M.D.,
Ph.D.                             -            -          370,000           -             1,225,000         -

- -----------------------
Richard Ascione, Ph.D.            -            -             -           50,000               -             -

- -----------------------
Paul Broome, MB.,
Ch.B., MFPM                       -            -             -           50,000               -              -

(1)  Market value of shares covered by in-the-money options on January 31, 1998,
     less option exercise price. Options are in-the-money if the market value of
     the shares covered thereby is greater than the option  exercise price.  The
     market value is the closing price at January 31, 1998, as quoted by Nasdaq.

</TABLE>

                Long-Term Incentive Plans - Awards in Fiscal Year
No long-term  incentive  plan awards were  granted  during the nine months ended
January 31, 1998.
                             Principal Shareholders

To  the  Company's  knowledge,   except  as  hereinafter  described,  no  single
shareholder of record owned or beneficially owned, as of May 31, 1998, more than
5% of the Company's  common stock.  As of May 31, 1998, Cede & Co., a nominee of
securities  depositories  for various segments of the financial  industry,  held
approximately 7,000,000 shares,  representing approximately 50% of the Company's
outstanding common stock, none of which was owned beneficially by Cede & Co. The
Company  believes  that  each  of  the  entities  or  individuals   named  below
beneficially owns 5% or more of the Company's common stock, based on a review of
filings made with the SEC.

         Name and Address of            Number of Shares     % of Common Stock
           Beneficial Owner
Smith Barney  Mutual Funds  Management,      1,481,900                10.4
Inc
388 Greenwich Street
Legal Dept, 20th Floor
New York, New York 10013

Philip C. Gevas                              1,949,050                13.7
P. O. Box 1049                                  (1)
Woodland, CA 95776

Richard L. Littenberg, M.D.                  1,146,250                 8.0
P. O. Box 1049
Woodland, CA 95776

Robert J. Scibienski, Ph.D.                  1,613,800                11.4
P. O. Box 1049
Woodland, CA 95776

All Executive Officers and                   2,176,416                15.3
Directors as a group (7 persons)
____________________________
(1)  Includes  90,000  shares in a trust of which Mr. Gevas is an  uncompensated
     trustee with no pecuniary interest in the trust assets.

                              Shareholder Proposals

If a shareholder intends to have a proposal presented at the next Annual Meeting
of  Shareholders,  such a  proposal  must  be  received  by the  Company  at its
principal executive offices prior to the end of fiscal year 1999.

                                  Miscellaneous

Coopers & Lybrand has been the Company's independent accountants for a number of
years and has been selected to continue in such capacity for the current  fiscal
year. It is  anticipated  that a  representative  from Coopers & Lybrand will be
available to answer  questions  raised at the Annual Meeting of Shareholders and
will be afforded the opportunity to make any statements the  representative  may
desire to make.

The Board of Directors  knows of no other matters that are likely to come before
the  meeting.  If any such  matters  should  properly  come before the  meeting,
however, it is intended that the persons named in the accompanying form of proxy
will vote such proxy in accordance with their best judgment on such matters.

By Order of the Board of Directors
- ------/s/------
Philip C. Gevas
Chairman and Secretary


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