<TABLE> <S> <C>
<ARTICLE> 5
<LEGEND>
This schedule contains summary financial information extracted from the Annual
Report on Form 10-K for the year ended January 31, 2000 and the Quarterly Report
on Form 10-Q for the quarter and three months ended April 30, 2000 and is
qualified in its entirety by reference to such financial statements.
</LEGEND>
<CIK> 0000840319
<NAME> Aphton Corporation
<MULTIPLIER> 1,000
<S> <C>
<PERIOD-TYPE> 3-MOS
<FISCAL-YEAR-END> JAN-31-2000
<PERIOD-START> FEB-1-2000
<PERIOD-END> APR-30-2000
<CASH> 13,817
<SECURITIES> 17,640
<RECEIVABLES> 8,152
<ALLOWANCES> 0
<INVENTORY> 0
<CURRENT-ASSETS> 32,127
<PP&E> 1,025
<DEPRECIATION> (865)
<TOTAL-ASSETS> 40,438
<CURRENT-LIABILITIES> (6,122)
<BONDS> 0
0
0
<COMMON> (16)
<OTHER-SE> (80,490)
<TOTAL-LIABILITY-AND-EQUITY> (40,438)
<SALES> 0
<TOTAL-REVENUES> 330
<CGS> 0
<TOTAL-COSTS> 0
<OTHER-EXPENSES> 3,490
<LOSS-PROVISION> 0
<INTEREST-EXPENSE> 0
<INCOME-PRETAX> (3,238)
<INCOME-TAX> 0
<INCOME-CONTINUING> (3,238)
<DISCONTINUED> 0
<EXTRAORDINARY> 0
<CHANGES> 0
<NET-INCOME> (3,238)
<EPS-BASIC> (0.20)
<EPS-DILUTED> (0.20)
</TABLE>