BECKMAN COULTER INC
10-K, 1999-02-22
LABORATORY ANALYTICAL INSTRUMENTS
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                                  FORM 10-K
                      SECURITIES AND EXCHANGE COMMISSION
                    WASHINGTON, D. C. 20549

      ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
                SECURITIES EXCHANGE ACT OF 1934

          For the fiscal year ended December 31, 1998
               Commission File Number  001-10109
                     BECKMAN COULTER, INC.

   4300 N. Harbor Boulevard, Fullerton, California 92834-3100
          (714) 871-4848 (Principal Executive Offices)

                State of Incorporation: Delaware
        I.R.S. Employer Identification No.:  95-104-0600

Securities registered pursuant to Section 12(b) of the Act:
   Title of each class: Common Stock, $.10 par value
   Name of each exchange on which registered: New York Stock Exchange

Securities registered pursuant to Section 12(g) of the Act:  None

Indicate by X mark whether the registrant (1) has filed all
reports required to be filed by Section 13 or 15(d) of the
Securities Exchange Act of 1934 during the preceding 12 months
(or for such shorter period that the registrant was required to
file such reports), and (2) has been subject to such filing
requirements for the past 90 days.  Yes (X) No ( ).

Indicate by X mark if disclosure of delinquent filers pursuant to
Item 405 of Regulation S-K is not contained herein, and will not
be contained, to the best of registrant's knowledge, in
definitive proxy or information statements incorporated by
reference in Part III of this Form 10-K or any amendment to the
Form 10-K.  ( )

Aggregate market value of voting stock held by non-affiliates  of
the registrant as of January 22, 1999: $1,505,218,255.00

Common Stock, $.10 par value, outstanding as of January 22, 1999:
28,636,732 shares.

  Documents incorporated by reference in this report:

     Documents incorporated                       Form 10-K part number
     Annual Report to stockholders for
     the fiscal year ended December 31, 1998      Part I and Part II

     Proxy Statement for the 1998 Annual
     Meeting of Stockholders to be held on
     April 8, 1999                                Part III

<PAGE>

                      BECKMAN COULTER, INC.
                             PART I

Item 1. Business

Overview

Beckman Coulter, Inc. (including its subsidiaries, the "Company")
is a world leader in providing systems that simplify and automate
laboratory processes. The Company designs, manufactures and
services a broad range of laboratory systems consisting of
instruments, reagents and related products that customers use to
conduct basic scientific research, drug discovery research and
diagnostic analysis of patient samples. Approximately 80% of the
Company's 1998 sales were for clinical diagnostics applications,
principally in hospital laboratories, while the remaining sales
were for life sciences and drug discovery applications in
universities, medical schools, and pharmaceutical and
biotechnology companies. The Company's clinical diagnostic
systems address over 75% of the hospital laboratory test volume,
including virtually all routine laboratory tests. The Company
believes that it is a worldwide market leader in its primary
markets, with well-recognized systems and a reputation for high-
quality, reliable service.

The Company's systems improve efficiency by automating customer
laboratory operations. The design of these systems draws upon the
Company's extensive expertise in the chemical, biological,
engineering and software sciences. Products for the clinical
diagnostics market consist of systems (analytical instruments,
reagents, accessories and software) that are used to detect,
quantify and classify various substances and cells of clinical
interest in human blood and other body fluids. Products for the
life science research market include centrifuges, pH meters, flow
cytometers, high performance liquid chromatographs,
spectrophotometers, laboratory robotic workstations, capillary
electrophoresis systems, liquid scintillation systems, DNA
sequencers and synthesizers, and the reagents and supplies for
their operation. The Company has an installed base of
approximately 75,000 systems in over 120 countries, which the
Company believes will provide a recurring stream of revenue and
cash flows from the sale of reagents, consumables and services
after initial placement of the system. Approximately 67% of the
Company's 1998 sales were derived from these "after sales", while
the remaining sales were derived from the direct placement of
systems.

Beckman Coulter's principal executive offices are located at 4300
N. Harbor Blvd., Fullerton, California 92835. Its mailing address
is P. O. Box 3100, Fullerton, CA 92834-3100. The telephone number
is (714) 871-4848.

Background

The formation of Beckman Coulter began on October 31, 1997 when
what was then Beckman Instruments, Inc. acquired Coulter
Corporation. Coulter became a wholly owned subsidiary of Beckman
Instruments, Inc.  Beckman Instruments, Inc. changed its name to
Beckman Coulter, Inc. on April 2, 1998.

The acquisition of Coulter was an extension of the Company's
strategy to solidify its position as a leading provider of
laboratory systems, adding Coulter's leading market position in
hematology and number two position in flow cytometry to Beckman's
established positions in clinical chemistry and life sciences.
Beckman and Coulter served substantially the same customer base
but had essentially no overlap in their product offerings. As a
result, the Company expects to be able to enhance the operating
efficiency of the combined entities through cross-selling and
reduced operating costs. To accomplish these objectives, the
Company initiated a program to streamline Coulter's operations
and then integrate the two companies.  This program, which was
substantially completed in 1998, included a global evaluation of
all subsidiary structures, sales and service approaches, and
staffing levels.  In particular, the Company's clinical
diagnostics commercial operations have been consolidated.  These
customers now deal with a single sales force, a single sales
administration contact, and a single service organization.

Beckman Instruments, Inc. was founded by Dr. Arnold O. Beckman in
1934, and entered the laboratory market by introducing the
world's first pH meter. Beckman became a publicly-traded
corporation in 1952. In 1968, Beckman expanded its laboratory
instrument focus to include healthcare applications in clinical
diagnostics. Beckman was acquired by SmithKline Corporation to
form SmithKline Beckman Corporation in 1982, and was operated as
a subsidiary of SmithKline Beckman until 1989 when it was
divested. Since that time, Beckman, now Beckman Coulter, Inc. has
operated as a fully independent, publicly-owned company.

Coulter Corporation was founded by Wallace and Joseph Coulter in
1958. The company was formed to market the "Coulter Counter," an
instrument used to determine the distribution of  red and white
cells in blood. This instrument was based on the "Coulter
Principle," which was developed by Wallace Coulter in 1948.  The
Coulter Principle involved an electronic, automatic way of
counting and measuring the size of microscopic particles. Coulter
Corporation was a private company and remained under the control
of the Coulter family until it was acquired by Beckman in 1997.

Customers and Markets

The two primary segments which the Company serves are the
clinical diagnostics market and the life science research market.
The Company's clinical diagnostics customers include hospital
clinical laboratories, physicians' offices and group practices
and commercial reference laboratories (large central laboratories
to which hospitals and physicians refer tests).  The Company's
life science research customers include universities conducting
academic research, medical research laboratories, pharmaceutical
companies and biotechnology firms. The Company's customers are
continually searching for processes and systems that can perform
tests faster, more efficiently and at lower costs. The Company
believes that its focus on automated, high-throughput systems
position it to capitalize on this need.

Virtually all new analytical methods and tests originate in
academic research in universities and medical schools. If the
utility of a new method or test is demonstrated by fundamental
research, it often will then be used by pharmaceutical
investigators, biotechnology companies, teaching hospitals or
specialized clinical laboratories in an investigatory mode. In
some cases, these new techniques eventually emerge in routine,
high-volume clinical testing at hospitals and reference labs.
Generally, instruments used at each stage from research to
routine clinical applications employ the same fundamental
processes but may differ in operating features such as number of
tests performed per hour and degree of automation. By serving
several customer groups with differing needs related through
common science and technology, the Company has the opportunity to
broadly apply and leverage its expertise.

The clinical diagnostics and the life science research markets
are each highly competitive and the Company encounters
significant competition in each market from many manufacturers,
both domestic and outside the United States. These markets
continue to be unfavorably impacted by the economic weakness in
Europe and Asia and government cost containment initiatives in
Europe as well as health care cost containment generally. The
life science research market also continues to be affected by
consolidation of pharmaceutical companies and governmental
constraints on research and development spending, especially
outside of the United States.

Attempts to lower costs and increase efficiencies have led to
consolidation among healthcare providers in the United States,
resulting in more powerful provider groups that leverage their
purchasing power with suppliers to contain costs. Preferred
supplier arrangements and combined purchases are becoming more
commonplace. Consequently, it has become essential for
manufacturers to provide cost-effective diagnostic systems to
remain competitive. In addition, consolidation has put pressure
on diagnostic equipment manufacturers to broaden their product
offerings to encompass a wider range of testing capability,
greater automation and higher volume capacity. Manufacturers that
have the ability to automate a wide variety of tests on
integrated workstations have a distinct competitive advantage.
Broad testing menus that include immunoassays and routine
chemistry tests are highly attractive to laboratories seeking to
reduce the number of vendors they utilize. Finally, consolidation
has made it increasingly important for suppliers to deploy a
highly focused sales force that is able to execute innovative
marketing approaches and to maintain a reliable after-sale
service network.

The size and growth of the Company's markets are influenced by a
number of factors, such as technological innovation in
bioanalytical practice, government funding for basic and disease-
related research (for example, heart disease, AIDS and cancer),
research and development spending by biotechnology and
pharmaceutical companies, and healthcare spending and physician
practice. As a result of the cost containment pressures and other
factors described above, the Company expects growth in both
markets to be flat or grow in the low single digits over the
short term. The Company expects worldwide healthcare expenditures
and diagnostic testing to increase over the long-term, primarily
as a result of the following three factors: (1) growing demand
for services generated by the aging of the world population, (2)
increasing expenditures on diseases requiring costly treatment
(for example, diabetes, AIDS and cancer), and (3) expanding
demand for improved healthcare services in developing countries.

Products - Overview

The Company offers a wide range of instrument systems and related
products, including consumables, accessories, and support
services. These can be grouped into the clinical diagnostics and
the life science research segments, by type of application.  The
following table shows the breakdown of sales between the two
market segments.

        PRODUCT SALES AS A PERCENT OF TOTAL PRODUCT SALES
                   FOR CATEGORIES REPRESENTING
                  MORE THAN 10 PERCENT OF SALES

                                                        1998  1997  1996
                                                        ----  ----  ----
           Clinical Diagnostics                          78    68    63
           Life Science Research                         22    32    37


Products - Overview - Clinical Diagnostics

The clinical diagnostics market encompasses the detection and
monitoring of disease by means of laboratory evaluation and
analysis of bodily fluids and other substances from patients.
This type of testing is referred to as "in vitro diagnostic" or
"IVD" testing. Due to its important role in the diagnosis and
treatment of patients, IVD testing is an integral part of overall
management of patient care. Additionally, IVD testing is
increasingly valued as an effective method of reducing healthcare
costs by reducing the length of hospital stays through accurate,
early detection of health disorders and management of treatment.

The major diagnostic fields that comprise the IVD industry
include clinical chemistry, immunochemistry, microbiology,
hematology and blood banking. The IVD industry market was
estimated to be $18 billion in 1998 and is estimated to grow at a
4% compound annual rate through the year 2002. The Company
primarily serves the hospital and reference laboratory customers
of the IVD market, which tend to use more precise, higher volume
and more automated IVD systems. Hospital and reference laboratory
customers constitute approximately $15.5 billion of the IVD market.

IVD systems are composed of instruments, reagents, consumables,
service and data management systems. Instruments typically have a
five-to ten-year life and serve to automate repetitive manual
tasks, improve test accuracy and speed the reporting of results.
Reagents are substances that react with the patient sample to
produce measurable, objective results. The consumables vary
across application segments but are generally items such as
sample containers, adapters, and pipette tips used during test
procedures. Reagents, accessories, consumables and services
generate significant ongoing revenues for suppliers. Sample
handling and preparation devices as well as data management
systems are becoming increasingly important components of IVD
systems. These system enhancements further improve safety and
reduce customer costs through automation. The Company believes
that the most important criteria customers use to evaluate IVD
systems are operating costs, reliability, reagent quality and
service, and that providing a fully integrated system that is
cost effective, reliable and easy to use results in loyalty among
customers who value consistency and accuracy in test results.

Products - Overview - Life Science Research

Life science research is the study of the characteristics,
behavior and structure of living organisms and their component
systems. Life science researchers utilize a variety of
instruments and related biochemicals and supplies in the study of
life processes, drug discovery and biotechnology. The Company
estimates that in 1997 annual sales to the global life science
research market for instrumentation and related service and
biochemicals totaled approximately $7.4 billion.

The portions of this market on which the Company focuses are
centrifugation and other separation systems, biorobotics for drug
screening, electrophoresis for research and development and
quality control uses, spectrophotometry, DNA sequencing and
synthesis, and liquid scintillation.  The Company estimates that
1998 industry wide sales of these portions totaled approximately
$5.5 billion in the aggregate. Trends in the life science
research industry include the growth in funding for drug
discovery by the pharmaceutical and biotechnology industries,
driven principally by the desire to accelerate drug discovery and
development, and the demand for increased automation and
efficiency in pharmaceutical and biotechnology laboratories.

An important application of the Company's systems is for use as a
part of the drug discovery process. Pharmaceutical groups require
the capability to screen millions of potential drug leads against
many new disease targets in shorter time periods. Makers of
bioanalytical instruments have addressed this need and helped to
make the new approach to drug discovery possible by combining the
detection capabilities of bioanalytical instruments with advances
in "high-throughput screening."  "High-throughput screening" is a
general term that refers to the automated systems and new
instruments currently being used to accelerate drug discovery.

Product Descriptions - Clinical Diagnostics Products

              Clinical Chemistry Systems - Overview

Clinical chemistry systems use electrochemical detection or
chemical reactions with patient samples to detect and quantify
substances of diagnostic interest (referred to as "analytes") in
blood, urine or other body fluids. Commonly performed tests
include protein, glucose, cholesterol, triglycerides,
electrolytes, and enzymes. The Company offers a range of
automated clinical chemistry systems to meet the testing
requirements of varying size laboratories, together with software
that allows these systems to communicate with central hospital
computers. To save time and reduce errors, systems identify
patient samples through barcodes. Automated clinical chemistry
systems are designed to be available for testing on short notice
twenty-four hours a day. The Company has generally configured its
systems for the work flow in medium and large hospitals, but the
systems also have application in regional reference labs. Over
180 tests for individual analytes are offered for use with the
Company's clinical chemistry systems, which range in price from
$45,000 to over $300,000.

   Clinical Chemistry Systems for Automated General Chemistry

                       SYNCHRON(R) Systems

The Company's SYNCHRON line of automated general chemistry
systems is a family of modular automated diagnostic instruments
and the reagents, standards and other consumable products
required to perform commonly requested diagnostic tests. The
SYNCHRON line was developed in response to changes in
reimbursement policies for hospital and clinical laboratories
that required them to be more efficient. The SYNCHRON Systems
have been designed as compatible modules which may be used
independently or in various combinations with each other to meet
the specific needs of individual customers.

The smallest of these modules, the SYNCHRON CX(R)3 (DELTA)
Analyzer, introduced in 1994, is an extension of the original
SYNCHRON CX(R)3 Analyzer that adds computer enhanced software
features, including sample identification using bar codes and up
to nine "on-board" chemistries.

The SYNCHRON CX(R)4, CX(R)5, and CX(R)7 Analyzers are random
access systems designed to perform routine chemistry profiles as
well as some special chemistry profiles. These models are
industry leading, innovative systems that are designed to improve
laboratory efficiency and enhance laboratory productivity. With
an extensive menu of routine chemistry, proteins, therapeutic
drugs and drugs of abuse, the SYNCHRON Systems can perform over
85% of the laboratory's general chemistry testing requirements.
In 1997, the CX series was enhanced with additional menu and
software designed to simplify operator interface and increase
throughput capabilities. These enhanced systems are designated
the SYNCHRON CX(R)9 ALX and the SYNCHRON CX(R)7 RTS.  SYNCHRON CX
Systems range in price from $49,000 to $185,000.

The launch in 1997 of the SYNCHRON LX(R)20 Clinical System
extended the product line into high volume laboratories. The
SYNCHRON LX20 has twice the throughput of the CX7 system as well
as options for additional detection capabilities that will
increase opportunity for test menu expansion. The SYNCHRON LX20
is also designed for improved sample handling to minimize
required operator interface. The SYNCHRON LX20, together with the
SYNCHRON CX product lines, provide product offerings for varying
size hospitals worldwide. Depending upon configuration and
accessories, SYNCHRON LX20 systems range in price from $150,000 to $300,000.

               Immunochemistry Systems - Overview

Immunochemistry systems, like clinical chemistry systems, use
chemical reactions to detect and quantify chemical substances of
diagnostic interest in blood, urine or other body fluids. The key
difference is that immunochemistry systems use antibodies
harvested from living organisms as the central component in
analytical reactions. These antibodies are created by the
organism's immune system and, when incorporated in test kits,
provide the ability to detect and quantify very low analyte
concentrations. Commonly performed tests assess thyroid function,
and screen and monitor for cancer and cardiac risk.
Immunochemistry systems have been designed to meet the special
requirements of these reactions and to simplify lab processes.
They are able to automatically identify individual patient sample
tubes and communicate with the laboratory's central computer. The
Company offers over 60 immunochemistry-based test kits for
individual analytes and a range of systems priced from $60,000 to $90,000.

   Immunochemistry Systems and Tests For Automated Immunoassay

The IMMAGE(R) Immunochemistry System, released in 1997, is a high
throughput analyzer for specific proteins, various immunologic
markers and therapeutic drugs. This system provides automated
random access testing which allows the operator to mix samples at
random, eliminating the need to analyze in batches.  The IMMAGE
System builds on the extensive installed base of its predecessor
immunochemistry analyzer, the ARRAY(R) 360 Protein and
Therapeutic Drug Monitoring System.  The ARRAY 360 was the
world's first computer enhanced, immunochemistry system offering
sample identification using bar codes and bidirectional
communication with a laboratory's central computer.  The IMMAGE
System sells for $70,000 to $90,000.

In 1996, the Company acquired Hybritech Incorporated
("Hybritech"), a San Diego based life sciences and diagnostics
company. The acquisition expanded the Company's capabilities for
the development and manufacture of high sensitivity immunoassays,
including cancer tests.  Paramount among these products are a
test for prostate specific antigen (PSA), utilized as an aid in
the detection (in conjunction with digital rectal examination)
and monitoring of prostate cancer. Another test is the OSTASE(R)
assay, which is used for the management of postmenopausal
osteoporosis, making it the first blood test cleared for such
use. During 1998, the Company obtained clearance for a test for
free PSA. This test is used in conjunction with the Company's PSA
test to assist in determining which patients require further
testing and evaluation.

In May of 1997, the Company acquired the Access(R) Immunoassay
System product line from Sanofi Diagnostics Pasteur. This product
line significantly expands the Company's menu of immunochemistry
diagnostic tests, particularly those that require high
sensitivity. The Access System serves as a disease state
management platform used to assist medical professionals to
detect and monitor critical parameters for thyroid function,
anemia, blood viruses, infectious disease, cancer, allergy,
fertility, therapeutic drugs, diabetes and cardiovascular and
skeletal diseases. An ongoing relationship was established with
Sanofi Diagnostics Pasteur to research and develop new tests,
primarily in the area of infectious disease and blood viruses.
The ACCESS System sells for approximately $125,000.

        Electrophoresis Systems For Clinical Diagnostics

The APPRAISE(R) Densitometer and the Paragon(R) Electrophoresis
Systems allow the Company to offer a full range of
electrophoresis products that provide specialized protein
analysis for clinical laboratories. Paragon reagent kits are used
in the diagnosis of diabetes, as well as cardiac, liver and other
diseases. The Appraise Densitometer can be used in conjunction
with Paragon reagent kits. It ranges in price from $17,000 to $24,000.

In 1995 the Company introduced the first capillary
electrophoresis system specifically designed for the clinical
laboratory, the Paragon CZE(R) 2000 System. This system is
designed to fully automate the manual and somewhat labor
intensive conventional electrophoresis analysis of serum protein
electrophoresis (SPE) and immunofixation electrophoresis (IFE).
Positioned to complement the Paragon gels and the APPRAISE
Densitometer, the Paragon CZE 2000 System is targeted at high volume
electrophoresis labs worldwide and sells for approximately $95,000.

                    Primary Care Diagnostics

The Company also produces single-use self-contained diagnostic
test kits for use in physicians' offices, clinics, hospitals and
other medical settings. The Hemoccult(R) occult blood test (OBT) is 
used as an aid in screening for gastrointestinal disease, most
importantly colorectal cancer.  In 1994, the Company introduced
the FlexSure(R) HP test kit.  This test is used as an aid in the
diagnosis of H-Pylori infection, which is associated with several
gastrointestinal diseases, including peptic ulcers and gastric
cancer.  A convenient whole blood version of the FlexSure(R) HP
test was launched in 1996.  In 1997, the Company released the
FlexSure(R) OBT immunochemical test.  This test is specific for
human blood and can detect lower gastrointestinal diseases like
colorectal cancer more accurately than the Hemoccult(R) test.  In
addition, the Company markets the ICON(R) test kits featuring a
high sensitivity pregnancy test widely used by health care
practitioners.  In 1997, the Company acquired the rights to and
introduced a user-friendly, next generation product, ICON(R) Fx
Strep A test kit that will replace the current ICON Strep A test.

The Company also recently began to introduce the COULTER(R)
Ac.T(TM) Hematology Analyzers.  These products are low cost
automated hematology systems designed to address the low volume
market.  Models of this system also offer features such as closed
tube sampling, which enhances bio-safe operation by reducing the
need to handle open sample tubes.

      Cell Counting and Characterization Systems - Overview

The Company's blood cell systems use the principles of physics,
optics, electronics and chemistry to separate cells of diagnostic
interest and then quantify and characterize them. These systems
fall into two categories: hematology and cytometry. Hematology
systems allow clinicians to study formed elements in blood such
as red and white blood cells and platelets. The most common
diagnostic result is a "CBC" or complete blood count, which
provides eight to twenty-three blood cell parameters. Flow
cytometers can extend analysis beyond blood to include bone
marrow, tumors and other cells. The rise of the AIDS epidemic and
the need to monitor subclasses of white cells moved cytometry
from largely a research technique into general clinical practice.
These systems are automated, use bar codes to identify samples
and can communicate with central computers.

    Cell Counting and Characterization Systems For Hematology

The Company's hematology product line reflects the clinical
diagnostic market's trend toward increasingly distinct high and
low volume segments. The Company currently manufactures eight
primary systems; the first three systems are designed for the
high volume segment and the remaining five systems are designed
for the lower volume segment.

The systems in the higher volume segment utilize volume,
conductivity and light scatter (VCS) technology in addition to
conventional, electrical aperture-impedance (Coulter Principle)
technology.  Unlike other technologies, the Coulter VCS method
counts and characterizes white blood cells while maintaining the
native integrity of the white blood cells throughout the
analysis.  The systems in the lower volume segment rely
exclusively upon electrical aperture-impedance technology.

                 High Volume Hematology Systems

COULTER(R) GEN.S(TM) Hematology System - The COULTER GEN.S System
was introduced in 1996.  It is the Company's state-of-the-art
automated hematology system, providing walkaway, whole blood
analysis for CBCs, five-part white blood cell differential, red
cell morphology and reticulocyte analysis with automated slide-
making from a single blood aspiration. The System automates
manual interpretation and result verification through its data
management workstation.

COULTER(R) STKS(TM) Hematology System - The COULTER STKS is a
cost-effective system designed for high volume clinical
laboratories. This system is particularly well suited for
commercial reference laboratories which have minimal requirements
for automated reticulocytes, but need the ability to measure aged
specimens accurately. The STKS hematology system provides a CBC
and five-part white blood cell differential, red cell morphology,
and semi-automated reticulocyte analysis.

COULTER(R) MAXM(TM) Hematology System - The COULTER MAXM
hematology system combines the computing power and many of the
technology features of the larger COULTER STKS hematology system
within a compact, fully automated bench-top design for moderate
throughput. The COULTER MAXM hematology system offers the same
comprehensive white cell differential and reticulocyte results as
the COULTER STKS hematology system and makes Coulter's advanced
VCS technology affordable for moderate volume testing
laboratories. The system is also an ideal back-up instrument in
high volume testing facilities.

High volume hematology systems sell in the $40,000 to $130,000
price range.

                  Low Volume Hematology Systems

COULTER(R) ONYX(TM) Hematology Instruments - The COULTER ONYX
analyzer provides a cost-effective option for laboratories that
require only a CBC and three-part screening differential.  The
COULTER ONYX analyzer is available in either a single-sample
loading or autoloading configuration for walk-away automation.

COULTER(R) MD(TM) II Hematology Instruments - The COULTER MD II,
which was introduced in 1994, is designed to meet the needs of
the low volume and "stat" test market.  The COULTER MD II
analyzer is simple to operate and cost effective, making it ideal
for the hospital laboratory second and third shift or by a
physician office or group practice.  The COULTER MD II analyzer
interfaces with a unique software module (called the "Remote
Access Laboratory System" or "RALS").  The RALS enables remote
operation of the instrument. These instruments are placed at
multiple locations amidst the patient population. A standard user
interface enables a central laboratory to communicate with the
analyzer and control its operation on-line.  As a result, samples
can be analyzed by untrained operators under central laboratory
supervision, thereby providing test result validation, quality
assurance, and centralized data management at reduced cost.

The low volume hematology systems typically sell in the price
range of $7,500 to $30,000.

                   Flow Cytometry Systems

Flow cytometry systems include an instrument, consumables and
related accessories to enable and enhance the performance of
these instruments.

COULTER EPICS(R) ALTRA(TM) Cell Sorter/Flow Cytometer - The
COULTER EPICS ALTRA Cytometer is a state-of-the-art cell sorter
and flow cytometer for advanced diagnostics and research. It is
designed to perform sophisticated cell analysis and sorting
applications using the Company's extensive portfolio of reagents.
The COULTER EPICS ALTRA instrument simultaneously performs
complex multi-parameter applications such as DNA analysis,
physiologic measurements, chromosome enumeration and the study of
the hematopoetic process. The cell sorting capability of the
system allows for the rapid separation of very large numbers of
specific cell populations from a heterogeneous mixture. ALTRA
systems typically sell for $200,000 to $400,000.

COULTER EPICS(R) XL(TM) Flow Cytometer with System II(TM)
Software -- The COULTER EPICS XL Cytometer with System II
Software is a state-of-the-art benchtop flow cytometer used
primarily to analyze white blood cells in clinical and clinical
research settings. Because the system is flexible and upgradeable
with varying sample preparation systems, it has proven successful
in different environments, from research labs to high and low
volume hospital and commercial labs.  These systems generally
sell for $65,000 to $110,000.

COULTER TQ-Prep(TM) - The Coulter TQ-Prep was introduced in 1997.
This third generation product provides a consistent, standardized
method for preparing whole blood for flow cytometric analysis.
These products sell for $15,000 to $20,000.

Product Descriptions - Life Science Research Products

The Company offers a wide range of life science research
discovery systems that are used to advance basic understanding of
life processes and in the related activities of therapeutic
development. Product categories include centrifuges, flow
cytometers, life sciences laboratory automation, DNA sequencers
and synthesizers, high performance liquid chromatography
("HPLC"), capillary electrophoresis, spectrophotometry and liquid
scintillation.

Centrifuges separate liquid samples based on the density of the
components. Samples are rotated at up to 130,000 revolutions per
minute to create forces that exceed 1,000,000 times the force of
gravity. These forces result in a nondestructive separation that
allows proteins, DNA and other cellular components to retain
their biological activity. Centrifuges are offered in a wide
range of models priced from $2,000 to $250,000.

Flow cytometers rapidly count and categorize multiple types of
cells in suspension. Common research applications include blood,
bone marrow and tumor cells for the study of AIDS, leukemias and
lymphomas. These systems are also useful in clinical applications
and sell in the $70,000 to $400,000 range.

Life science research laboratory automation consists of
integrated workstations and robotics that automatically perform
exacting and repetitive processes in biotechnology and drug
discovery laboratories. Operations include the dispensing,
measuring, dilution and mixing of samples and analysis of
reactions. A key application is for high throughput screening of
candidate compounds in drug discovery research. These systems
become functional through sophisticated scheduling and data
handling software. Prices range from $50,000 to $500,000.

DNA sequencers and synthesizers allow researchers to determine
their component sequence through electrophoretic separation or to
assemble strands of DNA molecules. These techniques are central
to biotechnology science and the genetic understanding of life
processes. Systems sell in the range of $12,000 to $90,000.

HPLC uses pressurized solvents to mobilize sample mixtures
through columns packed with solid or gel phase separating agents.
This technique is capable of separating very complex mixtures of
both organic and inorganic molecules. The Company focuses on
biologically related applications, including protein
purification, with systems that range from $20,000 to $50,000. In
addition, the Company also provides specialized software that is
capable of recording, manipulating and archiving data from
multiple HPLC systems. This type of software is essential to the
pharmaceutical development process and installations can range
from $20,000 to over $1,000,000.

Capillary electrophoresis uses the electrical charge found on
biological molecules to separate mixtures into their component
parts. Its chief advantages are its ability to process very small
sample volumes, separation speed and high resolution. The
technique is considered a complement to HPLC. The Company has
systems for basic research and pharmaceutical methods development
and quality control that sell in the range of $30,000 to $60,000.

Spectrophotometry is the optical measurement of compounds in
liquid mixtures. Among its applications is the ability to measure
changes during biological reactions. The Company's
spectrophotometers are characterized by adaptive software that
allows users to control the time, temperature and wavelength of
light used for measurement while computing and recording experimental 
results. Spectrophotometers sell in the $5,000 to $30,000 range.

Liquid scintillation techniques allow researchers to insert
radioactive "labeled" atoms into compounds that then are
introduced into biological systems. The compounds can be traced
to a specific tissue or waste product by measuring the amount of
radioactive label that is present with a liquid scintillation
counter. Liquid scintillation systems sell in the $16,000 to $30,000 range.

Competition

The markets for the Company's products are highly competitive,
with many companies participating in one or more parts of each
market segment. Competitors in the clinical diagnostics market
include Abbott Laboratories (Abbott Diagnostics Division), Bayer
Diagnostics, Dade Behring, Inc., Becton Dickinson and Company,
Johnson & Johnson (Ortho Diagnostics Division), Roche (Roche
Boehringer Mannheim Diagnostics Division) and Sysmex Corporation
of America (a subsidiary of TOA Medical Electronics Co. Ltd.).
Competitors focused more directly in the life science research
market include Amersham Pharmacia Biotech p.l.c., Bio-Rad
Laboratories, Inc., Hewlett-Packard Company, Hitachi, Packard
BioScience Company, The Perkin-Elmer Corporation, Sorvall
Products LP and Waters Corporation. Competitors include divisions
or subsidiaries of corporations with substantial resources. In
addition, the Company competes with several companies that offer
reagents, consumables and service for laboratory instruments that
are manufactured by the Company and others.

The Company competes primarily on the basis of improved
laboratory productivity, product quality, products combining to
meet multiple instrument needs, technology, product reliability,
service and price. Management believes that its extensive
installed instrument base provides the Company with a competitive
advantage in obtaining both follow-on instrument sales and After
Sales business.

Research and Development

The Company's new products originate from four sources:  (1)
internal research and development programs; (2) external
collaborative efforts with individuals in academic institutions
and technology companies; (3) devices or techniques that are
generated in customers' laboratories; and (4) business and
technology acquisitions. Development programs focus on production
of new generations of existing product lines as well as new
product categories not currently offered. Areas of pursuit
include innovative approaches to cell characterization,
immunochemistry, molecular biology, advanced electrophoresis
technologies, automated sample processing and information
technologies. The Company's research and development teams are
skilled in optics, chemistry, electronics, software and
mechanical and other engineering disciplines, in addition to a
broad range of biological and chemical sciences.

Both Beckman and Coulter historically invested considerable
capital on research and development efforts, contributing to
their leadership in their respective markets and a consistent
flow of new products. The Company's research and development
expenditures were $171.4 million in fiscal 1998, $123.6 million
in 1997, and $108.4 million in 1996.

Sales and Service

The Company has sales in over 120 countries and maintains its own
marketing, service and sales forces in major markets throughout
the world. Most of the Company's products are distributed by the
Company's sales groups; however the Company employs independent
distributors to serve those markets that are more efficiently
reached through such channels.

The Company's sales representatives are technically educated and
trained in the operation and application of the Company's
products. The sales force is supported by a staff of scientists
and technical specialists in each product line and in each major
scientific discipline served by the Company's products.

In addition to direct sales of its instruments, the Company
leases certain instruments to its customers, principally those
used for clinical diagnostic applications in hospitals. This
method of instrument placement is a significant competitive
factor for the clinical diagnostics market.

The Company's ability to provide immediate after sales service
and technical support is critical to customer satisfaction. This
includes capabilities to provide immediate technical support by
phone and to deliver parts or have a service engineer on site
within hours. To have such capabilities on a global basis
requires a major investment in personnel, facilities, and other
resources. The Company's large, existing installed base of
instruments makes the required service and support infrastructure
financially viable. The Company considers its reputation for
service responsiveness and competence and its worldwide sales and
service network to be important competitive assets.

Patents and Trademarks

To complement and protect the innovations created by the
Company's research and development efforts, the Company has an
active patent protection program which includes approximately 750
active U.S. patents and patent applications. Of this number,
approximately 280 relate to the life science research segment and
the remaining 470 relate to the clinical diagnostics segment. The
Company also files important corresponding applications in
principal foreign countries. The Company has taken an aggressive
posture in protecting its patent rights; however, no one patent
is considered essential to the success of the business.

The Company's primary trademarks are "Beckman" and "Coulter",
with the trade name being "Beckman Coulter".  During 1998, the
Company also adopted a new logo.  The Company vigorously protects
its primary trademarks, which are used on the Company's products
and are recognized throughout the worldwide scientific and
diagnostic community.  The Company owns and uses secondary
trademarks on various products, but none of these secondary
trademarks is considered of primary importance to the business.

Year 2000 Compliance

Information with respect to this subject is incorporated by
reference to the section entitled "Management's Discussion and
Analysis" of the Company's Annual Report to Stockholders for the
year ended December 31, 1998.

Government Regulations

Certain of the Company's products are subject to regulations of
the U.S. Food and Drug Administration (the "FDA").  These laws
and regulations require products to be developed and manufactured
in accordance with "good manufacturing practices".  The laws and
regulations also require the products to be safe and effective
and require the labeling of the products to conform with specific
requirements.  Testing is conducted to demonstrate performance
claims and to provide other necessary assurances. Clinical
systems and reagents must be reviewed by the FDA before sale and,
in some instances, are subject to product standards, other
special controls, or a formal FDA premarket approval process.
New federal regulations under the Clinical Laboratory Improvement
Amendments of 1988 will, if fully implemented, require regulatory
review and approval of quality assurance protocols for the
Company's clinical reagent products.  While adding to the overall
regulatory review process, this is not expected to materially
affect the sale of the Company's products.  Certain of the
Company's products are subject to comparable regulations in other
countries as well.

In 1993 the member states of the European Union (EU) began
implementation of their plan for a new unified EU market with
reduced trade barriers and harmonized regulations.  The EU
adopted a significant international quality standard, the
International Organization for Standardization Series 9000
Quality Standards ("ISO 9000").  The Company's manufacturing
operations in its Brea, Carlsbad, Fullerton, Palo Alto,
Porterville and San Diego, California; Miami and Hialeah,
Florida; Florence, Kentucky; Allendale, New Jersey; Sharon Hill,
Pennsylvania; Chaska, Minnesota; Naguabo, Puerto Rico; Galway,
Ireland; Australia, France, Germany, Hong Kong, and South Africa
facilities have been certified as complying with the requirements
of ISO 9000. Many of the Company's international sales and
service subsidiaries have also been certified, including those
located in Australia, Austria, Canada, China, France, Germany,
Italy, the Netherlands, Poland, Singapore, South Africa, Spain,
Sweden, Switzerland and the United Kingdom.

The design of the Company's products and the potential market for
their use may be directly or indirectly affected by U.S. and
foreign regulations concerning reimbursement for clinical testing
services.  The configuration of new products, such as the
SYNCHRON(R) series of clinical analyzers, reflects the Company's
response to the changes in hospital capital spending patterns
such as those engendered by the U.S. Medicare Diagnostic Related
Groups ("DRGs"). Under the DRG system, a hospital is reimbursed a
fixed sum for the services rendered in treating a patient,
regardless of the actual cost of the services provided. Japan,
France, Germany and Italy are among other countries that are in
the process of adopting reimbursement policies designed to lower
the cost of healthcare.

Medicare reimbursement of inpatient capital costs incurred by a
hospital (to the extent of Medicare utilization) is in a 10-year
transition period begun in 1991 from the "capital cost pass-
through" payment methodology to a "prospective capital" payment
methodology based on DRGs.  To date, the Company has not
experienced, and does not expect to experience in the future, any
material financial impact from the change in Medicare's payment
for inpatient capital costs.

The current health care reform efforts in the United States and
in some foreign countries are expected to further alter the
methods and financial aspects of doing business in the health
care field.  The Company is closely following these developments
so that it may position itself to take advantage of them.
However, the Company cannot predict the effect on its business of
these reforms should they occur nor of any other future
government regulation.

Environmental Matters

The Company is subject to federal, state, local and foreign
environmental laws and regulations. Although the Company
continues to make expenditures for environmental protection, it
does not anticipate any significant expenditures in order to
comply with such laws and regulations which would have a material
impact on the Company's operations or financial position.  The
Company believes that its operations comply in all material
respects with applicable federal, state, and local environmental
laws and regulations.

To address contingent environmental costs, the Company
establishes reserves when the costs are probable and can be
reasonably estimated.  The Company believes that, based on
current information and regulatory requirements (and taking third
party indemnities into consideration), the reserves established
by the Company for environmental expenditures are adequate.
Based on current knowledge, to the extent that additional costs
may be incurred that exceed the reserves, the amounts are not
expected to have a material adverse effect on the Company's
operations, financial condition, or liquidity, although no assurance 
can be given in this regard.

In 1983, the Company discovered organic chemicals in the
groundwater near a waste storage pond at its manufacturing
facility in Porterville, California.  Soil and groundwater
remediation have been underway at the site since 1983.  In 1989,
the U.S. Environmental Protection Agency issued a final Record of
Decision specifying the soil and groundwater remediation
activities to be conducted at the site.  The Company has
completed substantially all of the required work.  SmithKline
Beckman, the Company's former controlling stockholder, agreed to
indemnify the Company with respect to this matter for any costs
incurred in excess of applicable insurance, eliminating any
impact on the Company's earnings or financial position.
SmithKline Beecham p.l.c., the surviving entity of the 1989
merger between SmithKline Beckman and Beecham, assumed the
obligations of SmithKline Beckman in this respect.

In 1987, soil and groundwater contamination was discovered on
property in Irvine, California (the "property") formerly owned by
the Company.  In 1988, The Prudential Insurance Company of
America ("Prudential"), which purchased the property from the
Company, filed suit against the Company in U.S. District Court in
California for recovery of costs and other alleged damages with
respect to the soil and groundwater contamination.  In 1990, the
Company entered into an agreement with Prudential for settlement
of the lawsuit and for sharing current and future costs of
investigation, remediation and other claims.

Soil and groundwater remediation of the property have been in
process since 1988.  During 1994, the County agency overseeing
the site soil remediation formally acknowledged completion of
remediation of a major portion of the soil, although there remain
other areas of soil contamination that may require further
remediation.  In July 1997, the California Regional Water Quality
Control Board, the agency overseeing the site groundwater
remediation, issued a closure letter for the upper water bearing
unit.  The Company and Prudential continued to operate a
groundwater treatment system throughout 1998 and expect to
continue its operation in 1999.

Investigations on the property are continuing.  During 1998, two
additional areas of soil requiring remediation were identified.
Work on one area was completed in 1998.  Work on the second area
should be completed in 1999.  The Company believes that
additional remediation costs, if any, beyond those already
provided for the contamination discovered by the current
investigations will not have a material adverse effect on the
Company's operations, financial position, or liquidity.  However, 
there can be no assurance that further investigation will not reveal
additional soil or groundwater contamination or result in additional 
costs.

Employee Relations

As of December 31, 1998, the Company had approximately 7,300
employees located in the United States and approximately 2,700
employees in international operations.  The Company believes its
relations with its employees are good.

Geographic Area Information

Information with respect to the above-captioned item is
incorporated by reference to Note 16, "BUSINESS SEGMENT
INFORMATION" of the Consolidated Financial Statements of the
Company's Annual Report to Stockholders for the year ended
December 31, 1998.

Forward Looking Statements

This 10-K report and its exhibits contain forward-looking
statements, including among other items, statements regarding the
potential growth of the Company's markets, the position of the
Company's products in those markets, and the expected results of
the Company's marketing strategies.  These forward-looking
statements are based on the Company's expectations and are
subject to a number of risks and uncertainties, some of which are
beyond the Company's control.  Actual outcomes could differ from
those anticipated by these forward-looking statements as a result
of a number of factors, including, among other things, the impact
of economic conditions in Europe and Asia, government cost
containment initiatives, reduction in potential market as a
result of consolidation among customers, introduction of
competitive systems or products, and the actual extent and timing
of cost savings.

Item 2.  Properties

The Company's primary instrument assembly and manufacturing
facilities are located in Fullerton, Brea, and Palo Alto,
California; Chaska, Minnesota; and Hialeah, Opa Locka and Miami
Lakes, Florida.  Component manufacturing support facilities for
parts and electronic subassemblies are located in Fullerton and
Porterville, California.  An additional manufacturing facility is
located in Galway, Ireland.  Reagents are manufactured in
Carlsbad, San Diego and Palo Alto, California; Chaska, Minnesota;
Naguabo, Puerto Rico; Florence, Kentucky; Galway, Ireland;
Germany; France; Mexico; Japan; Brazil; Australia; Argentina
Venezuela and Hong Kong.

Part of the Company's computer software products business is
located in Allendale, New Jersey and its facility for the
production of Hemoccult(R) test kits and related products is
located in Sharon Hill, Pennsylvania. A portion of the Company's
laboratory robotics operations (Sagian) are conducted in leased
facilities in Indianapolis, Indiana. The Company's principal
distribution locations are in Brea and Fullerton, California;
Chaska, Minnesota; Somerset, New Jersey; Frankfurt, Germany; and
Paris, France. The Company's European Administration Center is
located in Nyon, Switzerland.

The Company owns the facilities located in Carlsbad, Fullerton,
and Porterville, California; Naguabo, Puerto Rico; and some of
the facilities in Hialeah, Florida. All of the other facilities
are leased.  All manufacturing facilities located outside of the
U.S. are leased with the exception of Germany, France, Japan,
Brazil and Australia.  In October 1998, the Company announced
that it was relocating the reagent manufacturing operations
conducted in San Diego, California and Naguabo, Puerto Rico to
the Carlsbad, California and Chaska, Minnesota facilities.  These
relocations are expected to be completed by the end of 1999.

The Brea and Palo Alto, California; Miami, Florida; and Chaska,
Minnesota facilities previously were owned by the Company.  On
June 25, 1998, the Company sold the four properties.  At the same
time, the Company entered into long-term ground leases for the
California and Minnesota properties and Coulter entered into a
long-term ground lease for the Miami property. The initial term
of each of the leases is twenty years, with options to renew for
up to an additional thirty years.  The aggregate proceeds from
the sale of the four properties (paid in cash at closing) totaled
$242.8 million before closing costs and transaction expenses.
These proceeds were used to reduce the debt incurred in financing
the acquisition of Coulter.

The Company believes that its production facilities meet
applicable government environmental, health and safety
regulations, and industry standards for maintenance, and that its
facilities in general are adequate for its current business.

Item 3. Legal Proceedings

The Company and its subsidiaries are involved in a number of
lawsuits which the Company considers ordinary and routine in view
of its size and the nature of its business.  The Company does not
believe that any ultimate liability resulting from any such
lawsuits will have a material adverse effect on its operations,
financial position, or liquidity.  However, no assurance can be given 
as to the ultimate outcome with respect to such lawsuits.  The resolution
of such lawsuits could be material to the Company's operating
results for any particular period, depending upon the level of
income for such period.

Item 4. Submission of Matters to a Vote of Security Holders

No matters were submitted to a vote of stockholders during the
fourth quarter of 1998.

Executive Officers of the Company

The following is a list of the executive officers of the Company
as of February 4, 1999, showing their ages, present positions and
offices with the Company and their business experience during the
past five or more years.  Officers are elected by the Board of
Directors and serve until the next annual Organization Meeting of
the Board.  Officers may be removed by the Board at will.  There
are no family relationships among any of the named individuals,
and no individual was selected as an officer pursuant to any
arrangement or understanding with any other person.

John P. Wareham, 57, Chairman of the Board, President and 
                     Chief Executive Officer

Mr. Wareham has been Chairman of the Board since February, 1999, 
Chief Executive Officer since September 1998, and President of the 
Company since 1993.  He served as the Company's Chief Operating 
Officer from 1993 to September 1998 and as Vice President, 
Diagnostic Systems Group from 1984 to 1993.  Prior thereto, he 
had been President of Norden Laboratories, Inc., a wholly owned 
subsidiary of SmithKline Beckman engaged in developing, manufacturing
and marketing veterinary pharmaceuticals and vaccines.  Mr. Wareham 
first joined SmithKline Corporation, a predecessor of SmithKline Beckman,
in 1968.  He is a director of the Health Industry Manufacturers Association.
Mr. Wareham has been a director of the Company since 1993.

Albert R. Ziegler, 60, Senior Vice President, Diagnostics Commercial
                       Operations

Mr. Ziegler was named Senior Vice President, Diagnostics
Commercial Operations in January, 1999.  He had been Vice
President, Clinical Chemistry Division since October 1997 and
Vice President, Diagnostics Development Center since 1994.  He
joined the Company in 1986 as Vice President, North America
Operations for the Diagnostic Systems Group.  Prior thereto, he
had been President of Branson Ultrasonics Corporation, a
manufacturer of industrial ultrasound instruments and a
subsidiary of SmithKline Beckman until the divestiture of
SmithKline Beckman's industrial instruments businesses in 1984.
Mr. Ziegler first joined SmithKline Beckman in 1971.

Edgar E. Vivanco, 55, Senior Vice President, Diagnostics Development and
                      Corporate Manufacturing

Mr. Vivanco was named Senior Vice President, Diagnostics
Development and Corporate Manufacturing in January, 1999.  He had
been President of Coulter Corporation and Vice President of the
Cellular Analysis Division since November 1997, and previously
was Vice President of the Biotechnology Development Center.  Mr.
Vivanco joined Beckman in 1971 as a microbiologist at the
Microbics Operations in La Habra, California. In 1973, he moved
to Carlsbad as a Development Microbiologist and became Production
Manager in 1975, Manufacturing Manager in 1978, and Site Manager
in 1986.  In 1987, he became Technical Operations Manager for the
Diagnostics Operations and in 1990, became Director of Worldwide
Reagents and Chemical Processing.

Dennis K. Wilson, 63, Vice President, Finance and Chief Financial Officer

Mr. Wilson has been Vice President, Finance and Chief Financial
Officer of the Company since 1993.  He served as Vice President,
Treasurer of the Company from 1989 until his current appointment.
Prior thereto, he had been Vice President, Corporate Accounting
and Assistant Controller of SmithKline Beckman since 1984.  Mr.
Wilson first joined the Company in 1969.

Jack Finney, 60, Vice President, Bioresearch Division

Mr. Finney has been Vice President, Bioresearch Division since
1997.  He first joined the Company in 1962 as a customer service
specialist, became product line manager in 1965 and marketing
manager in 1971 at Beckman's Spinco Division in Palo Alto,
California.  He became Manager in 1981 of Altex Scientific
Operations in Berkeley, California and in 1985 Vice President and
Manager of the Altex Division in San Ramon, California.  In 1991,
he was named Vice President of Product Development for the Spinco
Business Unit, and in 1994, was assigned overall responsibility
for the centrifuge business.

James T. Glover, 48, Vice President and Controller

Mr. Glover has been Vice President and Controller of the Company
since 1993.  From 1989 until assuming his current position, he
was Vice President, Controller - Diagnostic Systems Group.  Mr.
Glover joined the Company in 1983, serving in several management
positions, including a two-year term at Allergan, Inc., then a
Company affiliate.  Prior to 1983, he held management positions
with KPMG LLP and another Fortune 500 Company.

William H. May, 56, Vice President, General Counsel and Secretary

Mr. May has been Vice President, General Counsel and Secretary of
the Company since 1985 and has been General Counsel and Secretary
of the Company since 1984.  Mr. May first joined the Company in 1976.

Fidencio Mares, 52, Vice President, Human Resources and Corporate
                  Communications

Mr. Mares was named Vice President, Human Resources and Corporate
Communications of the Company in 1995.  Prior thereto he had been
President of The Gas Company of Hawaii.  Before that he was
Senior Vice President of Administration and Human Resources for
Pacific Resources, Inc., Corporate Wage and Salary Manager and
Corporate Human Resources Services Manager for Getty Oil
Company/Texaco, Inc., and held various human resources managerial
positions at Southern California Edison.

Paul Glyer, 42, Treasurer

Mr. Glyer has been Treasurer of the Company since 1993.  From 1995
to 1998 he additionally assumed the position of Director, Corporate
Business Development and Licensing.  He served as Assistant
Treasurer since 1989 when he first joined the Company.

PART II

Item 5.  Market for the Registrant's Common Stock and Related Stockholder 
Matters

As of January 22, 1999 there were approximately 7,614 holders of record of 
the Company's common stock.  During 1998 the Company paid three consecutive
quarterly dividends of fifteen cents per share of common stock, and one
dividend of sixteen cents per share, for a total of sixty-one
cents per share for the year.  During 1997, the Company paid four
consecutive quarterly dividends of fifteen cents per share of
common stock, for a total of sixty cents per share for the year.
Under the terms of the Company's principal credit agreement,
which expires on October 31, 2002, dividend payments are limited
but not prohibited.  To date this limitation has not had an
impact on the Company's dividends and is not expected to have an
impact in the foreseeable future.  Additional information with respect 
to the above-captioned item is incorporated herein by reference to the
section entitled "QUARTERLY INFORMATION (UNAUDITED)" of the
company's annual report to stockholders for the year ended December 
31, 1998.

Item 6.  Selected Financial Data

Information with respect to the above-captioned Item is
incorporated herein by reference to the section entitled
"SELECTED FINANCIAL INFORMATION" of the Company's Annual Report
to Stockholders for the year ended December 31, 1998.

Item 7.  Management's Discussion and Analysis of Financial Condition 
and Results of Operations

Information with respect to the above-captioned Item is
incorporated herein by reference to the section entitled
"MANAGEMENT'S DISCUSSION AND ANALYSIS" of the Company's Annual
Report to Stockholders for the year ended December 31, 1998.

Item 7A.  Quantitative and Qualitative Disclosures About Market Risk

Information with respect to the above-captioned Item is
incorporated by reference to the section entitled "FINANCIAL RISK
MANAGEMENT" of the Company's Annual Report to Stockholders for
the year ended December 31, 1998.

Item 8.  Financial Statements and Supplementary Data

Information with respect to the above-captioned Item is
incorporated by reference to the sections entitled "FINANCIAL
REVIEW", "CONSOLIDATED BALANCE SHEETS", "CONSOLIDATED STATEMENTS
OF OPERATIONS", "CONSOLIDATED STATEMENTS OF STOCKHOLDERS'
EQUITY", "CONSOLIDATED STATEMENTS OF CASH FLOWS", "QUARTERLY
INFORMATION", "INDEPENDENT AUDITORS' REPORT" and the notes to
these sections of the Company's Annual Report to Stockholders for
the year ended December 31, 1998.

Item 9.  Changes In and Disagreements With Accountants On Accounting and 
Financial Disclosures

None.

PART III

Item 10.  Directors and Executive Officers of the Registrant

Directors - the information with respect to directors required by
this Item is incorporated herein by reference to those parts of
the Company's Proxy Statement for the Annual Meeting of
Stockholders to be held April 8, 1999 entitled "ELECTION OF
DIRECTORS" and "ADDITIONAL INFORMATION ABOUT BOARD OF DIRECTORS."

Executive Officers - The information with respect to executive
officers required by this Item is set forth in Part I of this report.

Item 11.  Executive Compensation

The information with respect to executive compensation required
by this item is incorporated by reference to that part of the
Company's Proxy Statement for the Annual Meeting of Stockholders
to be held April 8, 1999 entitled "EXECUTIVE COMPENSATION",
excluding those sections entitled "Organization and Compensation
Committee Report on Executive Compensation" and "Performance Graph".

Item 12.  Security Ownership of Certain Beneficial Owners and Management

The information with respect to security ownership required by
this Item is incorporated by reference to that part of the
Company's Proxy Statement for the Annual Meeting of Stockholders
to be held April 8, 1999 entitled "SECURITY OWNERSHIP OF CERTAIN
BENEFICIAL OWNERS AND MANAGEMENT."

Item 13.  Certain Relationships and Related Transactions

The information with respect to certain relationships and related
transactions required by this Item is incorporated by reference
to that part of the Company's Proxy Statement for the Annual
Meeting of Stockholders to be held April 8, 1999 entitled "BOARD
OF DIRECTORS INFORMATION, Compensation Committee Interlocks and
Insider Participation."

PART IV

Item 14.  Exhibits, Financial Statement Schedules, and Reports on Form 8-K

     (a)(1), (a)(2) Financial Statements and Financial Statement Schedules

     The financial statements and financial statement schedules
filed as part of the report are incorporated by reference in the
"INDEX OF FINANCIAL STATEMENTS AND SCHEDULES" following this Part IV.

     (a)(3)    Exhibits

               Management contracts and compensatory plans or arrangements
               are identified by *.

          2.1  Stock Purchase Agreement among Coulter Corporation, The
               Stockholders of Coulter Corporation and the Company, dated
               as of August 29, 1997 (incorporated by reference to Exhibit
               2.1 of the Company's Report on Form 8-K dated November 13,
               1997, File No. 001-10109). (Note: Confidential treatment has
               been obtained for portions of this document.)

          3.1  Third Restated Certificate of Incorporation of the Company,
               June 5, 1992 (incorporated by reference to Exhibit 3.1 of
               the Company's Annual Report to the Securities and Exchange
               Commission on Form 10-K for the fiscal year ended December
               31, 1992, File No. 001-10109).

          3.2  Amended and Restated By-Laws of the Company, as of November
               30, 1994 (incorporated by reference to Exhibit 3.2 of the
               Company's Annual Report to the Securities and Exchange
               Commission on form 10-K for the fiscal year ended December
               31, 1994, File No. 001-10109).

          3.3  Fourth Restated Certificate of Incorporation dated April 2,
               1998 (incorporated by reference to Exhibit 3 of the
               Company's Quarterly Report to the Securities and Exchange
               Commission on Form 10-Q for the quarter ended March 31,
               1998, File No. 001-10109).

          4.1  Specimen Certificate of Common Stock (incorporated by
               reference to Exhibit 4.1 of Amendment No. 1 to the Company's
               Form S-1 registration statement, File No. 33-24572).

          4.2  Rights Agreement between the Company and Morgan Shareholder
               Services Trust Company, as Rights Agent, dated as of March
               28, 1989 (incorporated by reference to Exhibit 4 of the
               Company's current report on Form 8-K filed with the
               Securities and Exchange Commission on April 25, 1989, File
               No. 1-10109).

          4.3  First amendment to the Rights Agreement dated as of March
               28, 1989 between the Company and First Chicago Trust Company
               of New York (formerly Morgan Shareholder Services Trust
               Company), as Rights Agent, dated as of June 24, 1992
               (incorporated by reference to Exhibit 1 of the Company's
               current report on Form 8-K filed with the Securities and
               Exchange Commission on July 2, 1992, File No. 001-10109).

          4.4  Senior Indenture between the Company and The First National 
               Bank of Chicago as Trustee, dated as of May 15, 1996, filed
               in connection with the Form S-3 Registration Statement filed
               with the Securities and Exchange Commission on April 5,
               1996, File No. 333-02317 (incorporated by reference to
               Exhibit 10.1 of the Company's Quarterly Report to the
               Securities and Exchange Commission on Form 10-Q for the
               quarterly period ended June 30, 1996, File No. 001-10109).

          4.5  7.05% Debentures Due June 1, 2026, filed in connection with
               the Form S-3 Registration Statement filed with the
               Securities and Exchange Commission on April 5, 1996, File
               No. 333-02317 (incorporated by reference to Exhibit 10.2 of
               the Company's Quarterly Report to the Securities and
               Exchange Commission on Form 10-Q for the quarterly period
               ended June 30, 1996, File No. 001-10109).

          4.6  Amendment 1998-1 to the Company's Employees' Stock Purchase
               Plan dated December 9, 1998. 

          4.7  Stockholder Protection Rights Agreement dated as of February
               4, 1999 (incorporated by reference to Exhibit 4 of the
               Company's Form 8-K filed with the Securities and Exchange
               Commission on February 8, 1999, File No. 99523266).

          10.1 Credit Agreement dated as of October 31, 1997 among the
               Company as Borrower, the Initial Lenders and the Initial
               Issuing Banks named therein, and Citicorp USA, Inc. as Agent
               (incorporated by reference to Exhibit 10.1 of the Company's
               Quarterly Report to the Securities and Exchange Commission
               on Form 10-Q for the quarterly period ended September 30,
               1997, File No. 001-10109).

          10.2 Guaranty dated as of October 31, 1997 made by each Guarantor
               Subsidiary (as defined in the Credit Agreement, Exhibit 10.1
               herein) of the Company, in favor of the Lender Parties (as
               defined in the Credit Agreement) (incorporated by reference
               to Exhibit 10.2 of the Company's Quarterly Report to the
               Securities and Exchange Commission on Form 10-Q for the
               quarterly period ended September 30, 1997, File No. 001-
               10109).

          10.3 Line of Credit Agreement dated as of June 26, 1998 and Line
               of Credit Promissory Note in favor of Mellon Bank, N.A.,
               dated as of March 25, 1998.

          10.4 Loan Agreement (Multiple Advance), dated September 30, 1993,
               between Beckman Instruments (Japan) Limited and the
               Industrial Bank of Japan, Limited (English translation,
               including certification as to accuracy; original document
               executed in Japanese) (incorporated by reference to Exhibit
               10.31 of the Company's Annual Report to the Securities and
               Exchange Commission on Form 10-K for the fiscal year ended
               December 31, 1993, file No. 001-10109).

          10.5 Term Loan Agreement, dated as of September 30, 1993, between
               Beckman Instruments (Japan) Limited and Citibank, N.A.,
               Tokyo Branch (incorporated by reference to Exhibit 10.22 of
               the Company's Annual Report to the Securities and Exchange
               Commission on Form 10-K for the fiscal year ended December
               31, 1993, File No. 001-10109).

          10.6 Term Loan Agreement, dated as of December 9, 1993, between
               Beckman Instruments (Japan) Limited and The Dai-Ichi Kangyo
               Bank Limited (English translation, including certification
               as to accuracy; original document executed in Japanese)
               (incorporated by reference to Exhibit 10.23 of the Company's
               Annual Report to the Securities and Exchange Commission on
               Form 10-K for the fiscal year ended December 31, 1993, File
               No. 001-10109).

          10.7 Benefit Equity Amended and Restated Trust Agreement between
               the Company and Mellon Bank, N.A., as Trustee, for
               assistance in meeting stock-based obligations of the
               Company, dated as of February 10, 1997 (incorporated by
               reference to Exhibit 10.7 of the Company's Annual Report to
               the Securities and Exchange Commission on Form 10-K for the
               Fiscal Year ended December 31, 1997, File No. 001-10109).

        * 10.8 The Company's Annual Incentive Plan for 1997, adopted by the
               Company in 1997 (incorporated by reference to Exhibit 10.1
               of the Company's Quarterly Report to the Securities and
               Exchange Commission on Form 10-Q for the quarterly period
               ended June 30, 1997, File No. 001-10109.

        * 10.9 The Company's Incentive Compensation Plan of 1990, amended
               and restated April 4, 1997, with amendments approved by
               stockholders April 3, 1997 and effective January 1, 1997
               (incorporated by reference to Exhibit 10 of the Company's
               Quarterly Report to the Securities and Exchange Commission
               on Form 10-Q for the quarterly period ended March 31, 1997,
               File No. 001-10109).

       * 10.10 Amendment to the Company's Incentive Compensation Plan of
               1990 adopted December 5, 1997 (incorporated by reference to
               Exhibit 4.1 to Post-Effective Amendment No. 1 to the Form
               S-8 Registration Statement filed January 13, 1998,
               Registration No. 333-24851.

       * 10.11 The Company's Incentive Compensation Plan, as amended by the
               Company's Board of Directors on October 26, 1988 and as
               amended and restated by the Company's Board of Directors on
               March 28, 1989 (incorporated by reference to Exhibit 10.16
               of the Company's Annual Report to the Securities and
               Exchange Commission on Form 10-K for the fiscal year ended
               December, 31 1989, File No. 001-10109). 

       * 10.12 Amendment to the Company's Incentive Compensation Plan,
               adopted December 5, 1997 (incorporated by reference to
               Exhibit 4.2 to Post Effective Amendment No. 1 to the Form
               S-8 Registration statement, filed January 13, 1998,
               Registration No. 33-31573).

       * 10.13 Restricted Stock Agreement and Election (Cycle Three -
               Economic Value Added Incentive Plan), adopted by the Company
               in 1996 (incorporated by reference to Exhibit 10.15 of the
               Company's Annual Report to the Securities and Exchange
               Commission on Form 10-K for the fiscal year period ended
               December 31, 1996, File No. 001-10109).

       * 10.14 Form of Restricted Stock Agreement, dated as of January 3,
               1997, between the Company and certain of its Executive
               Officers and certain other key employees (incorporated by
               reference to Exhibit 10.1 of the Company's Quarterly Report
               to the Securities and Exchange Commission on Form 10-Q for
               the quarterly period ended June 30, 1997, File No. 001-
               10109).

       * 10.15 The Company's Supplemental Pension Plan, adopted by the
               Company October 24, 1990 (incorporated by reference to
               Exhibit 10.4 of the Company's Annual Report to the
               Securities and Exchange Commission on Form 10-K for the
               fiscal year ended December, 31 1990, File No. 001-10109).

       * 10.16 Amendment 1995-1 to the Company's Supplemental Pension Plan,
               adopted by the Company in 1995, effective as of October 1,
               1993 (incorporated by reference to Exhibit 10.17 of the
               Company's Annual Report to the Securities and Exchange
               Commission on Form 10-K for the fiscal year ended December
               31, 1996, File No. 001-10109).

       * 10.17 Amendment 1996-1 to the Company's Supplemental Pension Plan,
               dated as of December 9, 1996 (incorporated by reference to
               Exhibit 10.18 of the Company's Annual Report to the
               Securities and Exchange Commission on Form 10-K for the
               fiscal year ended December 31, 1996, File No. 001-10109).

       * 10.18 Stock Option Plan for Non- Employee Directors (Amended 
               and Restated effective as of August 7, 1997), incorporated 
               by reference to Exhibit 4.1 of the Company's Registration
               Statement on Form S-8 filed with the Securities and 
               Exchange Commission on October 8, 1997, Registration 
               No. 333-37429.

       * 10.19 Form of Change in Control Agreement, dated as of May 1, 
               1989, between the Company, certain of its Executive 
               Officers and certain other key employees (incorporated by
               reference to Exhibit 10.34 of the Company's Annual
               Report to the Securities and Exchange Commission
               on Form 10-K for the fiscal year ended December
               31, 1989, File No. 001-10109).

       * 10.20 Agreement Regarding Retirement Benefits of Albert Ziegler,
               dated June 16, 1995, between the Company and Albert Ziegler
               (incorporated by reference to exhibit 10.22 of the Company's
               Annual Report to the Securities and Exchange Commission on
               Form 10-K for the fiscal year ended December 31, 1995, File
               No. 001-10109).

       * 10.21 Agreement Regarding Retirement Benefits of Fidencio M.
               Mares, adopted and dated April 30, 1996, between the Company
               and Fidencio M. Mares (incorporated by reference to Exhibit
               10.3 of the Company's Quarterly Report to the Securities and
               Exchange Commission on Form 10-Q for the quarterly period
               ended June 30, 1996, File No. 001-10109).

         10.22 Amendment 1997-1 to the Company's Employees' Stock Purchase
               Plan, adopted effective January 1, 1998 and dated October
               20, 1997 (incorporated by reference to Exhibit 10.3 of the
               Company's Quarterly Report to the Securities and Exchange
               Commission on Form 10-Q for the quarterly period ended
               September 30, 1997, File No. 001-10109).

       * 10.23 The Company's Amended and Restated Deferred Directors' Fee
               Program, amended as of June 5, 1997 (incorporated by
               reference to Exhibit 10.6 of the Company's Quarterly Report
               to the Securities and Exchange Commission on Form 10-Q for
               the quarterly period ended September 30, 1997, File No. 001-
               10109).

       * 10.24 Amendment 1997-2 to the Company's Supplemental Pension Plan,
               adopted as of October 31, 1997 (incorporated by reference to
               Exhibit 10.7 of the Company's Quarterly Report to the
               Securities and Exchange Commission on Form 10-Q for the
               quarterly period ended September 30, 1997, File No. 001-
               10109).

       * 10.25 Form of Restricted Stock Award Agreement between the Company
               and its non-employee Directors, effective as of October 3,
               1997 (incorporated by reference to Exhibit 4.1 of the
               Company's Registration Statement on Form S-8 filed with the
               Securities and Exchange Commission on October 8, 1997,
               Registration No. 333-37429).

       * 10.26 Form of Stock Option Grant for non-employee Directors
               (incorporated by reference to Exhibit 4.3 of the Company's
               Registration Statement on Form S-8 filed with the Securities
               and Exchange Commission on October 8, 1997, Registration No.
               333-37429).

       * 10.27 The Company's Employees' Stock Purchase Plan, amended and
               restated as of November 1, 1996, filed in connection with
               the Form S-8 Registration Statement filed with the
               Securities and Exchange Commission on December 19, 1995,
               File No. 33-65155 (incorporated by reference to Exhibit
               10.29 of the Company's Annual Report to the Securities and
               Exchange Commission on Form 10-K for the fiscal year ended
               December 31, 1997, File No. 001-10109).

       * 10.28 The Company's Option Gain Deferral Program, dated January
               14, 1998 (incorporated by reference to Exhibit 4.2 of Post-
               Effective Amendment No. 1 to the Form S-8 Registration
               Statement filed with the Securities and Exchange Commission
               on January 13, 1998, Registration No. 333-24851).

       * 10.29 Form of Coulter's Special Incentive Plan and Sharing Bonus
               Plan, assumed by the Company October 31, 1997 (incorporated
               by reference to Exhibit 10.38 of the Company's Annual Report
               to the Securities and Exchange Commission on Form 10-K for
               the fiscal year ended December 31, 1997, File No. 001-10109).

         10.30 Distribution Agreement, dated as of April 11, 1989, among
               SmithKline Beckman Corporation the Company and Allergan,
               Inc. (incorporated by reference to Exhibit 3 to SmithKline
               Beckman Corporation's Current Report on Form 8-K filed with
               the Securities and Exchange Commission on April 14, 1989,
               File No. 1-4077).

         10.31 Amendment to the Distribution Agreement effective as of June
               1, 1989 between SmithKline Beckman Corporation, the Company
               and Allergan, Inc. (incorporated by reference to Exhibit
               10.26 of Amendment No. 2 to the Company's Form S-1 
               registration statement, File No. 33-28853).

         10.32 Cross-Indemnification Agreement between the Company and
               SmithKline Beckman Corporation (incorporated by reference to
               Exhibit 10.1 of Amendment No. 1 to the Company's Form S-1
               registration statement, File No. 33-24572). 

         10.33 Amendment No. 1 dated April 3, 1998 to the Credit Agreement
               by and among the Company, as borrower, the Initial Lenders
               and the Issuing Banks named therein, and Citicorp USA, Inc.
               as Agent dated October 31, 1997 (incorporated by reference
               to Exhibit 10.1 of the Company's Quarterly Report to the
               Securities and Exchange Commission on Form 10-Q for the
               quarter ended March 31, 1998, File No. 001-10109).

       * 10.34 Amendment No. 1998-1, adopted and effective as of April 2,
               1998 to the Company's 1998 Incentive Compensation Plan
               (incorporated by reference to Exhibit 10.2 of the Company's
               Quarterly Report to the Securities and Exchange Commission
               on Form 10-Q for the quarter ended March 31, 1998, File No.
               001-10109).

       * 10.35 1998 Annual Incentive Plan (AIP) (incorporated by reference
               to Exhibit 10.3 of the Company's Quarterly Report to the
               Securities and Exchange Commission on Form 10-Q for the
               quarter ended March 31, 1998, File No. 001-10109).

         10.36 Lease Agreement made as of June 25, 1998 among Beckman
               Coulter, Inc., NPDC-EY Brea Trust, and NPDC-RI Brea Trust
               (incorporated by reference to Exhibit 2.5 of the Company's
               current report on Form 8-K filed with the Securities and
               Exchange Commission on July 9, 1998, File No. 001-10109).

         10.37 Lease Agreement made as of June 25, 1998 between Beckman
               Coulter, Inc., and Cardbeck Chaska Trust (incorporated by
               reference to Exhibit 2.6 of the Company's current report on
               Form 8-K filed with the Securities and Exchange Commission
               on July 9, 1998, File No. 001-10109).

         10.38 Lease Agreement made as of June 25, 1998 between Coulter
               Corporation and Cardbeck Miami Trust (incorporated by
               reference to Exhibit 2.7 of the Company's current report on
               Form 8-K filed with the Securities and Exchange Commission
               on July 9, 1998, File No. 001-10109).

         10.39 Lease Agreement made as of June 25, 1998 among Beckman
               Coulter, Inc., NPDC-EY Palo Alto Trust, and NPDC-RI Palo
               Alto Trust (incorporated by reference to Exhibit 2.8 of the
               Company's current report on Form 8-K filed with the
               Securities and Exchange Commission on July 9, 1998, File No.
               001-10109).

         10.40 Lease Modification Agreement made as of June 25, 1998 among
               Beckman Coulter, Inc., NPDC-EY Brea Trust, and NPDC-RI Brea
               Trust (incorporated by reference to Exhibit 2.9 of the
               Company's current report on Form 8-K filed with the
               Securities and Exchange Commission on July 9, 1998, File No.
               001-10109).

         10.41 Lease Modification Agreement made as of June 25, 1998 among
               Beckman Coulter, Inc. and Cardbeck Chaska Trust
               (incorporated by reference to Exhibit 2.10 of the Company's
               current report on Form 8-K filed with the Securities and
               Exchange Commission on July 9, 1998, File No. 001-10109).

         10.42 Lease Modification Agreement made as of June 25, 1998 among
               Coulter Corporation and Cardbeck Miami Trust (incorporated
               by reference to Exhibit 2.11 of the Company's current report
               on Form 8-K filed with the Securities and Exchange 
               Commission on July 9, 1998, File No. 001-10109).

         10.43 Lease Modification Agreement made as of June 25, 1998 among
               Beckman Coulter, Inc., NPDC-EY Palo Alto Trust, and NPDC-RI
               Palo Alto Trust (incorporated by reference to Exhibit 2.12
               of the Company's current report on Form 8-K filed with the
               Securities and Exchange Commission on July 9, 1998, File No.
               001-10109).

         10.44 Guaranty of Lease, executed as of June 25, 1998, by Beckman
               Coulter, Inc. for the benefit of Cardbeck Miami Trust
               (incorporated by reference to Exhibit 2.13 of the Company's
               current report on Form 8-K filed with the Securities and
               Exchange Commission on July 9, 1998, File No. 001-10109).

       * 10.45 The Company's Amended and Restated Executive Deferred
               Compensation Plan dated October 28, 1998, effective as of
               September 1, 1998 (incorporated by reference to Exhibit 4.1
               of the Company's Registration Statement on Form S-8 filed
               with the Securities and Exchange Commission on December 18,
               1998, Registration No. 333-69249).

       * 10.46 The Company's Amended and Restated Executive Restoration
                Plan dated October 28, 1998, effective as of September 1,
                1998 (incorporated by reference to Exhibit 4.1 of the
                Company's Registration Statement on Form S-8 filed with the
                Securities and Exchange Commission on December 18,1998,
                Registration No. 333-69251).

        * 10.47 The Company's Amended and Restated Savings Plan dated
                December 24, 1998, effective as of September 1998
                (incorporated by reference to Exhibit 4.1 of the Company's
                Registration Statement on Form S-8 filed with the Securities
                and Exchange Commission on February 10, 1999, Registration
                No. 333-72081).

        * 10.48 Amendment 1998-1, adopted and effective as of April 2, 1998
                to the Company's 1998 Incentive Compensation Plan
                (incorporated by reference to Exhibit 10.2 of the Company's
                Quarterly Report to the Securities and Exchange Commission
                on Form 10-Q for the quarterly period ended March 31, 1998,
                File No. 001-10109)

          11.   Statement regarding computation of per share earnings: This
                information is incorporated by reference to the discussions
                of "Earnings (Loss) Per Share" located in Notes 1 and 15 of
                the Consolidated Financial Statements of the Company's
                Annual Report to Stockholders for the year ended December
                31, 1998.

          13.   WORDS ON NUMBERS

          21.   Subsidiaries.

          23.   Consent of KPMG LLP

          24.   Power of Attorney (included herein on the signature page).

          27.   Financial Data Schedule.

    (b)   Reports on Form 8-K During Fourth Quarter ended December 31, 1998.

           The following reports on Form 8-K were filed since September 30,
           1998

           Item 5.  Other Events.  Stockholder Protection Rights Agreement
           dated as of February 4, 1999 filed February 8, 1999


<PAGE>

                      Beckman Coulter, Inc.

                            INDEX TO
               FINANCIAL STATEMENTS AND SCHEDULES

The consolidated financial statements of the Company and the
related report of KPMG LLP, dated January 22, 1999 are 
incorporated by reference to the section entitled "WORDS ON
NUMBERS" filed as Exhibit 13 to this Form 10-K.

The information required to be reported in the Supplementary
Financial Schedule entitled, II Valuation and Qualifying Accounts
Accounts, for the three year period ended December 31, 1998 is
set forth in Note 17 Supplementary Information of the "NOTES TO
CONSOLIDATED FINANCIAL STATEMENTS" of the Company's Annual Report
to Stockholders for the year ended December 31, 1998. Schedules
not included herein have been omitted because they are not
applicable, are no longer required or the required information is
presented in the consolidated financial statements or in the
notes to the consolidated financial statements.

<PAGE>


SIGNATURES

     Pursuant to the requirements of Section 13 or 15(d) of the
Securities Exchange Act of 1934, the registrant has duly caused
this report to be signed on its behalf by the undersigned,
thereunto duly authorized.


                              BECKMAN COULTER, INC.

                              By   JOHN P. WAREHAM
                                   John P. Wareham
                                   Chairman of the Board, President
                                   and Chief Executive Officer

                         POWER OF ATTORNEY

     Each person whose signature appears below appoints John P.
Wareham, Dennis K. Wilson, William H. May, Paul Glyer and James
T. Glover, and each of them, as his or her true and lawful
attorneys-in-fact and agents with full power of substitution and
resubstitution, for him or her and in his or her name, place and
stead, in any and all capacities, to sign any or all amendments
to this Annual Report on Form 10-K, and to file the same, with
all exhibits thereto, and all documents in connection therewith,
with the Securities and Exchange Commission, granting unto said
attorneys-in-fact and agents, and each of them, full power and
authority to do and perform each and every act and thing
requisite and necessary to be done in and about the foregoing, as
fully to all intents and purposes as he or she might or could do
in person, hereby ratifying and confirming all that said
attorneys-in-fact and agents, or any of them or their
substitutes, may lawfully do or cause to be done by virtue hereof.

     Pursuant to the requirements of the Securities Exchange Act
of 1934, this report has been signed by the following persons on
behalf of the registrant and in the capacities and on the dates indicated.


Signature              Title                                   Date
- ---------              -----                                   ----

JOHN P. WAREHAM       Chairman of the Board, President     February 4, 1999
John P. Wareham       and Chief Executive Officer

D. K. WILSON          Vice President, Finance and Chief    February 4, 1999
Dennis K. Wilson      Financial Officer
                      (Principal Financial Officer)

JAMES T. GLOVER       Vice President and Controller        February 4, 1999
James T. Glover       (Principal Accounting Officer)

HUGH K. COBLE            Director                          February  4, 1999
Hugh K. Coble

CAROLYN K. DAVIS         Director                          February 4, 1999
Carolyne K. Davis, Ph.D.

<PAGE>

Signature                Title                                Date
- ---------                -----                                ----

PETER B. DERVAN          Director                          February 4, 1999
Peter B. Dervan, Ph.D.

RONALD W. DOLLENS        Director                          February 4, 1999
Ronald W. Dollens

CHARLES A. HAGGERTY      Director                          February 4, 1999
Charles A. Haggerty

GAVIN HERBERT            Director                          February 4, 1999
Gavin S. Herbert

VAN B. HONEYCUTT         Director                          February 4, 1999
Van B. Honeycutt

WILLIAM N. KELLEY        Director                          February 4, 1999
William N. Kelley, M.D.

C. RODERICK O'NEIL       Director                          February 4, 1999
C. Roderick O'Neil

BETTY WOODS              Director                          February 4, 1999
Betty Woods

<PAGE>


                         INDEX TO EXHIBITS
Exhibit
Number    Exhibit
- ------    -------

4.6       Amendment 1998-1 to the Company's Employees' Stock Purchase Plan
          dated December 9, 1998.

10.3      Line of Credit Agreement dated as of June 26, 1998 and Line of
          Credit Promissory Note in favor of Mellon Bank, N.A., dated as of
          March 25, 1998

13.       WORDS ON NUMBERS

21.       Subsidiaries

23.       Consent of KPMG Peat Marwick LLP

27.       Financial Data Schedule




EXHIBIT 4.6
                         AMENDMENT 1998-1

                    BECKMAN INSTRUMENTS, INC.
                  EMPLOYEES' STOCK PURCHASE PLAN


     WHEREAS, Beckman Coulter, Inc., formerly Beckman
Instruments, Inc. (the "Company") maintains the Beckman
Instruments, Inc. Employees' Stock Purchase Plan (the "Plan");
and

     WHEREAS, the Company has the right to amend the Plan, and
the Company desires to amend the Plan to reflect resolutions
adopted by the Company's Board of Directors to reflect the new
corporate name and to revise eligibility requirements;

     NOW, THEREFORE, the Plan is amended as follows:

     1.   All references to "Beckman Instruments, Inc." are
          changed to "Beckman Coulter, Inc." and the name of
          the Plan is changed to the "Beckman Coulter, Inc.
          Employees' Stock Purchase Plan" in order to reflect
          to the new corporate name approved April 2, 1998 by
          the Company's stockholders.

     2.   The word "full-time" in reference to regular employees
          is deleted from Sections 2(a), 2(b), and 2(c) and the
          second sentence in Section 2(c) is deleted, effective
          for the second option period in 1998.


     IN WITNESS WHEREOF, the Company has caused its duly
authorized officer to execute this Amendment to the Plan on
December 9, 1998.

                         BECKMAN COULTER, INC.


                         By:  FIDENCIO M. MARES
                              Fidencio M. Mares
                         Its: Vice President - Human Resources



                                                                EXHIBIT 10.3

Mellon Bank                                  Western Region
                                             Representative Office
                                             Global Corporate Banking
                                             400 South Hope Street
June 26, 1998                                Fifth Floor
                                             Los Angeles, CA  90071-2806

                                             (213)553-9500 Office
Mr. Eugene A. Blaho, CPA, CCM                (213)629-0492 Fax
Assistant Treasurer
Beckman Coulter, Inc.
2500 Harbor Blvd.
P.O. Box 3100
Fullerton, CA  92634


Dear Gene:

This letter reaffirms that Mellon Bank, N.A. ("Mellon") extends
to Beckman Coulter, Inc. ("Beckman") a line of credit in the
amount of $30,000,000 to be used in conjunction with our
Automated Borrowing Service as described in the Agreement Letter
dated and signed August 18, 1989.  Beckman can automatically
access this line daily on an as needed basis in order to balance
its daily cash position at Mellon.  Such borrowings will continue
to be priced at the Libor rate plus 100 basis points.  Libor will
be calculated based on the 30-day rate published by the Federal
Reserve Bank of New York.  There is no per annum fee associated
with this service.

This line will remain in effect until June 25, 1999 ("Expiration
Date") subject to the extension provisions in a Promissory Note
dated March 25, 1998 (executed copy attached).  After the
Expiration Date, unless Mellon and Beckman agree to extend the
interest rate stated above or negotiate another mutually
acceptable interest rate, the interest rate for all future
borrowings will revert to our Prime rate plus 200 basis points.

Please have the appropriate officer sign this letter and return
it to my attention.  Upon our receipt of this executed letter, a
copy will be attached as an additional document (as part of
Exhibit A) to the Letter Agreement dated and signed August 18, 1989.

We appreciate the continued confidence which Beckman places in
Mellon Bank and we look forward to continuing to service your
financial needs in the months ahead.

Sincerely,

GILL S. REALON
Gill S. Realon
Vice President
                                        Confirmed:  D. K. WILSON
                                        Title: V.P., Finance and CFO

<PAGE>

                              Beckman Instruments, Inc.

                                    Line of Credit

                                    Promissory Note
                    (for Automated Borrowing Service Borrowings)

$30,000,000                                       Pittsburgh, Pennsylvania

                                                  March 25, 1998

FOR VALUE RECEIVED, the undersigned, Beckman Instruments Inc.
(the "Borrower"), promises to pay to the order of Mellon Bank,
N.A. (the "Bank") on or before June 26, 1998 (the "Expiration
Date") the lesser of (i) the principal sum of $30,000,000, or
(ii) the aggregate unpaid principal amount of all loans made by
the Bank to the Borrower pursuant to our Line of Credit.  The
Borrower further promises to pay to the order of the Bank
interest due on the last Friday of each month and on December 31.

This promissory note shall be automatically extended without
amendment for a period of 364 days on the Expiration Date and on
each successive Expiration Date thereafter, provided that the
Agreement Letter dated and signed August 18, 1989 for the
Automated Borrowing Service is in effect on such Expiration Date.

All payments of principal and interest hereunder shall be due and
payable on or before 4:00 p.m., Pittsburgh time, on the day when
due and shall be direct debited from the designated account of
the Borrower at the Bank.  If such principal and interest is not
direct debited such payments shall be made to the Bank at its
office in Dollars in immediately available funds without setoff,
counterclaim or other deductions of any nature or automatically
debited from the account of the Borrower at the Bank.

Except as otherwise agreed to by the Bank and Borrower, if any
payment of principal or interest hereunder shall be due on a day
which is not a business day, such payment shall be made on the
next following business day and such extension of time shall be
included in computing interest in connection with such payment.

The Borrower hereby expressly waives presentment, demand, notice,
protest and all other demands and notices in connection with the
delivery, acceptance, performance, default or enforcement of this
Promissory Note, and any action for amounts due hereunder or
thereunder shall immediately accrue.

This Promissory Note shall be governed by, construed and enforced
in accordance with the laws of the Commonwealth of Pennsylvania.

                              Beckman Instruments, Inc.


                    By:  D. K. WILSON
                    Title:  V.P., Finance and Chief Financial Officer




                                
                                     
                                                               EXHIBIT 13
  
  
  
                             WORDS ON NUMBERS
                              Section of our
                       Annual Report to Stockholders
                            For the Year Ended
                             December 31, 1998
                                     
                                     
                             TABLE OF CONTENTS
                                     
  Selected Financial Information
  Financial Review
  Management's Discussion and Analysis
  Consolidated Balance Sheets
  Consolidated Statements of Operations
  Consolidated Statements of Stockholders' Equity
  Consolidated Statements of Cash Flows
  Notes to Consolidated Financial Statements
  Quarterly Information
  Report by Management
  Independent Auditors' Report
  Board of Directors
  Other Information
  
  Bar Chart: Income from Operations Before Special Charges* (millions)
  
  Year                           1994       1995     1996     1997    1998
  Income from Operations        $98.9    $ 110.8   $122.5   $104.4  $133.9
  
  
  Bar Chart:   EBITDA Before Special Charges* (millions)
  
  Year                 1994       1995        1996        1997     1998
  EBITDA             $161.4     $192.6      $217.4      $228.0   $305.9
  
  *Excludes pre-tax special charges in 1994, 1995, 1997 and 1998.
  
  Bar Chart:  Dividends Paid Per Common Stock
  
  Year                 1994       1995        1996        1997     1998
  Dividends Paid
  ($ Per Share)        $0.40     $0.44       $0.52       $0.60    $0.61
  
<PAGE>  
SELECTED FINANCIAL INFORMATION
Dollars in millions, except amounts per share
<TABLE>
<CAPTION>

Years Ended December 31,      1998       1997      1996      1995    1994
                              ----       ----      ----      ----    ----
<S>                       <C>        <C>       <C>        <C>      <C>
                                                               
Summary of Operations                                               
 Sales                    $1,718.2   $1,198.0  $1,028.0   $ 930.1  $888.6
                                                                    
 Operating income before      
  special charges (1)     $  133.9   $  104.4  $  122.5   $ 110.8  $ 98.9 
                                                                    
 Earnings before special
  and non-recurring 
  charges, after taxes    $   44.7   $   54.0  $   74.7   $  66.1  $ 56.9    
                                                                    
 Special charges:                                                   
 In-process research and                                            
  development                  -       (282.0)       -         -        -
 Restructuring charge,
   net of tax benefit        (11.2)    ( 36.4)       -      (17.2)   (9.6)     
 Non-recurring charges:                                                
 Changes in accounting
  principles                   -         -           -         -     (5.1)
                             --------------------------------------------     
Net earnings (loss)       $   33.5   $(264.4)   $  74.7   $  48.9  $ 42.2
                          ========   ========   =======   =======  ======                                                    
Diluted earnings per                                                
 share before
 special charges          $   1.52   $  1.88    $  2.58   $  2.29  $ 2.03
Diluted earnings (loss)
 per share                $   1.14   $ (9.58)   $  2.58   $  1.70  $ 1.50
Dividends paid per share                                         
 of common stock          $   0.61   $  0.60    $  0.52   $  0.44  $ 0.40
Shares outstanding
  (millions)                  28.4      27.6       28.0      28.3    28.0  
Weighted average common
 shares and dilutive
 common share equivalents
 (millions) (2)               29.3      27.6       28.9      28.8    28.1     
                                                                    
Other Information                                                   
 Total assets             $2,133.3  $2,331.0    $ 960.1   $ 907.8  $829.1
 Long-term debt,
  less current                                       
  maturities              $  982.2  $1,181.3    $ 176.6   $ 162.7  $117.3
 Working capital          $  237.3  $   81.8    $ 300.1   $ 282.1  $243.2
 EBIT before special       
  charges(1)(3)           $  153.5  $  118.9    $ 129.6   $ 113.5  $ 91.3
 Depreciation and
  amortization                                      
  expense                 $  152.4  $  109.1    $  87.8   $  79.1  $ 70.1
 EBITDA before special
  charges(1)(3)           $  305.9  $  228.0    $ 217.4   $ 192.6  $161.4
 EBITDA(3)                $  286.8  $ (113.4)   $ 217.4   $ 164.9  $150.1
 Debt to EBITDA before                                      
  special charges(1)           3.7       5.5        0.9       0.9     0.8
 Capital expenditures     $  174.9  $  110.7    $ 117.4   $ 110.0  $ 98.7
 Number of employees at
  December 31,              10,064    11,171      6,079     5,702   5,963

</TABLE>
  
  (1)Excludes pretax special charges.  Special charges include:  1)
     restructuring charges of $19.1, $59.4, $27.7 and $11.3 in 1998, 1997,
     1995 and 1994, respectively, and 2) a one time write-off of $282.0 of
     acquired in-process research and development relating to the Coulter
     acquisition in 1997.  Including these special charges, the Company
     reported operating income (loss) of $114.8, ($237.0), $83.1 and $87.6
     in 1998, 1997, 1995 and 1994 respectively.  The Company did not incur
     any special charges in 1996.
  
  (2)Under Generally Accepted Accounting Principles ("GAAP"), as the
     Company was in a net loss position in 1997, 1.0 million common share
     equivalents were not used to compute diluted loss per share, as the
     effect was antidilutive.

  (3)EBIT is earnings before interest expense and taxes; EBITDA is EBIT
     before depreciation and amortization.
  
  
                             FINANCIAL REVIEW
Dollars in millions, except amounts per share

Results Of Operations

The following table sets forth, for the periods indicated, the results of
operations as a percentage of sales and on a comparative basis:
<TABLE>
<CAPTION>
                                                              1998     1997
                                                              Compared Compared
 Years ended             % of             % of          % of  to       to
 December 31,     1998   Sales     1997   Sales   1996  Sales 1997 (2) 1996 (2)
                  ----   -----     ----   -----   ----  ----- -------- --------
<S>           <C>        <C>   <C>        <C>   <C>       <C>  <C>      <C>
                                                                
Sales:                                                             
  Clinical                                                         
  diagnostics $1,342.5    78.1 $  815.2    68.0 $  652.0  63.4 $ 527.3  $ 163.2
  Life science                                                     
  research       375.7    21.9    382.8    32.0    376.0  36.6    (7.1)     6.8
              --------   ----- --------   ----- -------- ----- -------  -------
Total sales   $1,718.2   100.0 $1,198.0   100.0 $1,028.0 100.0 $ 520.2  $ 170.0
              ========   ===== ========   ===== ======== ===== ======= ========
Cost of sales    920.6    53.6    609.7    50.9    477.8  46.5   310.9    131.9
              --------   ----- --------   ----- -------- ----- ------- --------
Gross profit     797.6    46.4    588.3    49.1    550.2  53.5   209.3     38.1
Selling,                                                           
 general &
 administra-
 tive            492.3    28.7    360.3    30.1    319.3  31.1   132.0    41.0
Research &                                                         
 development     171.4    10.0    123.6    10.3    108.4  10.5    47.8    15.2
              --------   ----- --------  ------ -------- -----  ------ -------
Operating                                                          
 income(1)       133.9     7.8    104.4     8.7    122.5  11.9    29.5   (18.1)
Net                                                                
 nonoperating
 expense          68.2     4.0     14.9     1.2     11.0   1.0    53.3     3.9
              --------   ----- --------  ------ -------- -----  ------ -------
Earnings                                                           
 before
 income
 taxes (1)        65.7     3.8     89.5     7.5    111.5  10.9   (23.8)  (22.0)
Income tax                                                         
 provision
  (1)             21.0     1.2     35.5     3.0     36.8   3.6   (14.5)   (1.3)
              --------   ----- --------  ------ -------- -----  ------ -------
Earnings                                                           
 before                                                             
 special
 charges,   
 after
 taxes(1)      $  44.7     2.6  $  54.0     4.5  $  74.7   7.3  $ (9.3) $(20.7)
Net earnings 
 (loss)        $  33.5     1.9  $(264.4)  (22.1) $  74.7   7.3  $ 297.9 $(339.1)
              --------   ----- --------  ------ -------- -----  ------- -------
Diluted                                                            
 earnings
 per share
 before
 special
 charges       $  1.52          $  1.88          $  2.58        $ (0.36)$(0.70)
Diluted                                                            
 earnings
 (loss)per   
 share         $  1.14          $ (9.58)         $  2.58        $ 10.72 $(12.16)
Dividends                                                      
 paid per
 share of 
 common
 stock         $  0.61          $  0.60          $  0.52        $  0.01 $ 0.08
               =======          =======          =======        ======= ======
</TABLE>

(1) Amounts exclude special charges.  Special charges include: l)
restructuring charges of $19.1, 1.1% of sales and $59.4, 5.0% of sales in
1998 and 1997, respectively, and 2) a one time write-off of $282.0, 23.5%
of sales, of acquired in-process research and development relating to the
Coulter acquisition in 1997. Including these special charges: 1) operating
income (loss) was $114.8, 6.7% of sales and $(237.0), (19.8%) of sales in
1998 and 1997, respectively, and 2) earnings (loss) before income taxes was
$46.6, 2.7% of sales and $(251.9), (21.0%) of sales, in 1998 and 1997,
respectively.  The Company did not incur any special charges in 1996.

(2) Parentheses indicate decreases from the comparative period.


Bar Chart:  SG&A as a % of Sales

Year                    1996            1997             1998
SG&A (% of Sales)       31.1            30.1             28.7

Bar Chart:  R&D Expenses Before Write-off of In-Process R&D (millions)

Year                    1996            1997                1998
R&D Expenses          $108.4          $123.6              $171.4

<PAGE>

Management's Discussion and Analysis

     The following review should be read in conjunction with the
consolidated financial statements and related notes included on pages 26
through 53.  Note that historical results and percentage relationships are
not necessarily indicative of operating results for any future periods.

Overview

     Beckman Coulter, Inc. is a world leader in providing systems that
simplify and automate laboratory processes.  We design, manufacture and
service a broad range of laboratory systems consisting of instruments,
reagents and related products that customers use to conduct basic
scientific research, drug discovery research and diagnostic analysis of
patient samples.  Approximately 80% of our 1998 sales were for clinical
diagnostics applications, principally in hospital laboratories, while the
remaining sales were for life science research applications (including drug
discovery) in universities, medical schools, and pharmaceutical and
biotechnology companies.  Our diagnostics systems address over 75% of the
hospital laboratory test volume, including virtually all of the routine
laboratory tests.  We believe we are a worldwide market leader in our
primary markets, with well-recognized systems and a reputation for high-
quality, reliable service.


1.   Acquisition Activities
     
     The primary focus of our acquisition strategy has been to broaden our
product offerings.  The following table lists some of our recent
acquisitions:

                         Product/technology    
       Company                 acquired         Acquisition date
       -------                 --------         ----------------
Coulter Corporation    Hematology & flow        October 1997
                       cytometry
Sanofi Diagnostics     Access(R) Immunoassay    April 1997
Pasteur                product line
 ("Sanofi")*
Sagian,                High throughput          December 1996
Inc.("Sagian")**       screening &
                         robotics technology
Genomyx, Inc.          DNA sequencing           October 1996
                       technology
Hybritech Incorporated Immunoassays & cancer    January 1996
("Hybritech")           diagnostics
- ---------------------- ---------------------    ------------                  
* Only the Access(R) Immunoassay product line of Sanofi was acquired.
** Only the Laboratory Robotics Division of Sagian was acquired.

On October 31, 1997, we acquired all of the outstanding capital stock of
Coulter Corporation ("Coulter") for $850.2 million, net of Coulter's cash
on hand of $24.8 million  at the acquisition date.  Coulter is the leading
manufacturer of in-vitro diagnostic systems for blood cell analysis.  We
discussed the details of this transaction and the accounting effects in our
annual report for 1997. This acquisition and the related financing lowered
our net earnings in 1998 and 1997 as a result of a substantial increase in
interest expense, amortization of intangible assets and goodwill and
various other adjustments resulting from purchase accounting.   A complete
discussion of our acquisition activities is provided in Note 3
"Acquisitions" of the Notes to Consolidated Financial Statements. In April
1998, our stockholders approved the change of our name to Beckman Coulter,
Inc.

2.   Events Impacting Comparability

Operating periods reported:
     
     Our financial statements include the assets and liabilities and the
operating results of subsidiaries operating outside the U.S.  Balance sheet
amounts for these subsidiaries are as of November 30, 1998 and November 30,
1997.  The operating results for these subsidiaries are for twelve-month
periods ending on those dates, except as noted below.  Note that, in order
to be consistent with the way we have historically reported our
international results, the reporting of Coulter's international results of
operations has been lagged by one month in 1998. Therefore, the results for
the year 1998 include only January through November sales and expenses for
Coulter outside the United States. The exclusion of one month's results for
Coulter international subsidiaries was not significant.

Acquired Research and Development:
     
     In 1997, the results of operations included a $282.0 million charge
for purchased in-process research and development.  This charge was a
direct result of the acquisition of Coulter and was related to projects
which have economic value but could not be capitalized under GAAP.

Goodwill and Intangible Assets:

     As a result of the acquisition of Coulter in 1997, we recorded $404.0
million as the fair market value of patents, trademarks and other
intangibles ("Intangible Assets") and $374.4 million as the excess of
purchase price and purchase and assumed liabilities over the fair market
value of identifiable net assets and in-process research and development
projects acquired ("Goodwill").  Upon finalization of purchase accounting
in the fourth quarter of 1998, certain adjustments were made to the values
of assets and liabilities recorded, which resulted in a reduction of
recorded Goodwill in the amount of $35.7 million.  Intangible Assets are
amortized using the straight-line method over their expected useful lives,
ranging from 15 to 30 years.  Goodwill is amortized on a straight-line
basis over 40 years.  See further discussion in Note 3 "Acquisitions" of
the Notes to Consolidated Financial Statements.

Restructuring Charges:
     
     As a result of revisions to the plans initiated in 1997 for Company
reorganization, in the fourth quarter of 1998, we recorded a restructuring
charge of $19.1 million.  This charge was in addition to the $59.4 million
restructuring charge recorded in 1997.  On an after-tax basis, the
restructuring charges were $11.2 million or $0.38 per share in 1998 and
$36.4 million or $1.32 per share in 1997. A more detailed discussion of the
restructuring charges is provided in Note 4 "Provision for Restructuring
Operations" of the Notes to Consolidated Financial Statements.
  
Sale-leaseback of Real Estate:

     During the second quarter of 1998, we sold our interest in properties
in Brea, California; Palo Alto, California; Chaska, Minnesota; and Miami,
Florida and leased them back from the buyers.  The aggregate proceeds from
the sale of the four properties totaled $242.8 million before closing costs
and transaction expenses. We used the cash from this sale primarily to
reduce the debt incurred in financing the acquisition of Coulter. Refer to
the detailed discussion of this transaction under Note 6 "Sale-leaseback of
Real Estate" of the Notes to Consolidated Financial Statements.

Sale of Assets:

     During 1998, we sold certain financial assets (primarily consisting of
customer lease receivables) as part of our plan to reduce debt and provide
funds for integration purposes.  The net book value of financial assets
sold was $67.7 million for which we received approximately $68.9 million in
cash proceeds.  In 1997, we sold similar assets with a net book value of
$34.2 million for cash proceeds of $35.7 million.  

     In December 1997, we entered into an agreement for the sale and
leaseback of certain instruments, which are subject to various three to
five year cancelable operating-type leases to customers.  These instruments
had a net book value of $37.0 million and were sold for cash proceeds of
$39.6 million.  The gain is being deferred and credited to income as an
adjustment to rent expense over the lease term.  Obligations under the
operating lease agreement are included in Note 14 "Commitments and
Contingencies" of the Notes to Consolidated Financial Statements.

     We have and will continue to evaluate opportunities to provide
additional cash flow by monetizing other assets during 1999 and beyond.
If these sales are consummated as expected, we believe they will generate
proceeds of approximately $30.0 million in 1999, less any costs to
complete the transactions.  See further discussion in Note 5 "Sales of
Asssets" of the Notes to Consolidated Financial Statements.

Tax Aspects:

   We do not expect that we will have to pay federal income taxes for our
consolidated U.S. federal income tax group over the next several years
primarily as a result of expenses related to the acquisition of Coulter.
These expenses include the Coulter bonus sharing plan payments, interest on
indebtedness and certain other expenses incurred in connection with the
Coulter acquisition.  The deferred income tax liability of $153.5 million,
which is related to the Coulter intangible assets acquired, will be reduced
by the tax effect of the amortization of the intangible assets, which is
not deductible for income tax purposes.

3.Results of Operations

1998 Compared with 1997:

     Sales for 1998 were $1,718.2 million, an increase of 43.4% over the
$1,198.0 million reported in 1997. The increase in sales is primarily
attributable to the inclusion in 1998 of a full year of sales from the
Coulter operations compared to two months in 1997.  In 1998 as in 1997,
international sales accounted for approximately half of total sales.
Foreign exchange rates negatively impacted sales growth by about 3.0
percentage points. Despite continuing market-driven pricing pressures and
adverse currency fluctuations, our core businesses remained strong.  For
example, in 1998 the Company signed a multi-year agreement with Kaiser
Permanente, the nation's largest non-profit health maintenance organization,
to provide clinical and hematology analyzers, along with related reagents,
supplies and service, for use in Kaiser Permanente medical centers, medical
office laboratories and clinics throughout the United States. We also
obtained significant new business with Ohio State University, University of
Washington and Emory University/Crawford Long Hospital in Georgia.
  
     Gross profit at 46.4% of sales was 2.7 percentage points lower than
the 1997 level of 49.1%. Unfavorable foreign currency fluctuations, lower
margins for Coulter products and competitive pricing pressures contributed
to the decline in gross profit percentage. Additionally, both the 1998 and
1997 gross profit included increased cost of sales for inventory recorded
at fair value as part of the Coulter acquisition.  Although gross profit
for the year declined in comparison to the prior year, gross profit in each
quarter of the current year showed a positive trend increasing from 42.5%
in the first quarter to 48.8% in the fourth quarter. We believe this trend
is the result of the synergies obtained from the continuing consolidation
and integration of the Beckman and Coulter organizations.  Although we
believe this positive trend will continue, we cannot guarantee that it will
or that the future rate of increase will be comparable to that in 1998.
  
     Selling, general and administrative expenses ("SG&A") at 28.7% of
sales were 1.4 percentage points lower than the 1997 level of 30.1%.
Research and development ("R&D") expenses were 10.0% as compared to 10.3%
of sales in 1997.  SG&A and R&D expenses were lower in 1998 compared to the
prior year as a percentage of sales, primarily due to the implementation of
integration activities.   SG&A expenses include goodwill and intangible
amortization expenses arising out of the Coulter acquisition of $24.7
million or 1.4% of sales in 1998 compared to $4.3 million or 0.3% of sales
in 1997.
  
     As a result, operating income before pretax special charges was $133.9
million or 7.8% of sales in 1998, compared with $104.4 million and 8.7% in
1997.  Although the trend in operating income before pretax special charges
during the four quarters in 1998 was favorable increasing from 2.1% in the
first quarter to 12.6% in the fourth quarter, we cannot guarantee the trend
will continue into the future.  Both the 1998 and 1997 operating income
before pretax special charges included increased cost of sales for
inventory recorded at fair value and on-going goodwill and intangible
amortization expenses arising out of the Coulter acquisition.  Without
these items, the operating margin would have been 9.6% in 1998 compared to
10.0% in 1997.
  
     As integration work progressed during 1998, acquisition-related costs
were lower than those originally anticipated at the end of 1997, while
plans to restructure pre-acquisition Beckman operations were expanded.  The
final purchase accounting entries resulted in a one-time reduction of $35.7
million in goodwill while a $19.1 million charge was recorded in the fourth
quarter to reflect the updated restructure plans.  This charge reduced the
reported operating income to $114.8 million for 1998.  In 1997 one-time
charges of $282.0 million for in-process research and development expenses
and restructure charges of $59.4 million (discussed previously in item 2)
resulted in the reported operating loss of $237.0 million.
  
     Incremental interest expense associated with the debt incurred by the
Company to fund the Coulter acquisition and reduced foreign exchange gains
increased net nonoperating expenses.  These were partially offset by gains
due to increased interest income from leases (some of which was
attributable to Coulter).
  
     The net earnings for 1998 were $33.5 million compared with a net loss
of $264.4 million in 1997.  The net loss in 1997 excluded any tax benefit
for the $282.0 million charge for in-process research and development since
it was not deductible for income tax purposes.
  
1997 Compared with 1996:
  
     Sales for 1997 were $1,198.0 million, an increase of 16.5% over the
$1,028.0 million reported in 1996.  The sales growth in constant currency
over the prior year was 20.2%.  More than half of the growth resulted from
the previously mentioned acquisition of Coulter Corporation.  Despite
continuing market-driven pricing pressures and adverse currency
fluctuations, core businesses grew in all geographic areas.  As an example,
the Company was able to leverage its product offerings that reduce total
laboratory cost, provide workstation consolidation and progressive
automation, into a $100.0 million, five-year contract signed with AmeriNet,
Inc., one of the largest healthcare purchasing organizations in the United
States.  In addition, a new contract was signed with University
Healthsystem Consortium ("UHC"), complementing the existing agreement with
Voluntary Hospitals of America ("VHA"), which acquired UHC.  In 1997 as in
1996, international sales accounted for approximately 50% of total sales.
  
     Gross profit at 49.1% of sales was 4.4 percentage points lower than
the 1996 level of 53.5%.  Increased cost of sales resulting from the
inventory written-up to market value in connection with the acquisition of
Coulter accounted for $11.3 million or one percentage point of the
reduction.  Unfavorable foreign currency fluctuations contributed another
one percentage point.  Lower margins for Coulter products and competitive
pricing pressures made up the balance of the percentage reduction.
  
     At 30.1% of sales, SG&A expenses were one percentage point lower than
the 1996 level of 31.1%, despite the costs of acquisition activities
incurred during the year.  R&D expenses remained at 1996 levels, at just
over 10% of sales.
  
     As a result, operating income before pretax special charges was $104.4
million or 8.7% of sales in 1997, compared with operating income of $122.5
million and 11.9% in 1996.  However, the 1997 operating income before
pretax special charges, unlike 1996 operating income, included increased
cost of sales related to inventory recorded at fair value and on-going
goodwill and intangible amortization expenses arising out of the Coulter
acquisition.  Without these items, the 1997 operating income margin would
have been 10.0%.
  
     One-time charges of $282.0 million for in-process research and
development expenses and restructure charges of $59.4 million (discussed
previously in item 2) resulted in the reported operating loss of $237.0
million.
  
     Incremental interest expense associated with the debt incurred to fund
the Coulter acquisition increased nonoperating expenses, but was partially
offset by gains due to hedging activities.
  
     The net loss for the year was $264.4 million compared with net
earnings of $74.7 million in 1996.  The 1997 net loss excluded any tax
benefit for the $282.0 million charge for in-process research and
development since it did not qualify as a deduction for income tax
purposes.
  
4.   Financial Condition

Liquidity and Capital Resources:

     Liquidity is our ability to generate sufficient cash flows from
operating activities to meet our obligations and commitments.  In addition,
liquidity includes the ability to obtain appropriate financing and to
convert those assets that are no longer required to meet existing strategic
and financing objectives into cash flows.  Therefore, liquidity cannot be
considered separately from capital resources that consist of current and
potentially available funds for use in achieving long-range business
objectives and meeting debt service commitments.

     Currently, our liquidity needs arise primarily from:
     - debt service on the substantial indebtedness we incurred in connection
       with the Coulter acquisition;
     - funding the costs of integrating the operations of Beckman and
       Coulter;
     - working capital requirements; and
     - capital expenditures.

     In 1998 cash used in operations was $1.8 million compared to cash
provided by operations of $137.8 million in 1997 and $139.1 million in
1996. The decrease is largely the result of a decrease of $191.0 million in
accounts payable and accrued liabilities.  This change primarily relates to
payments towards the purchase and assumed liabilities recorded as part of
the Coulter acquisition. Additional cash outflow resulted from a $24.1
million reduction in the 1997 restructure reserve partially offset by a
$19.1 million restructuring charge recorded in 1998.  These decreases were
partially offset by an increase in net earnings, after adding back the effects
of depreciation, amortization and special charges.  Additionally, the 1998
results included $68.9 million in cash proceeds from the sale of sales-type
lease receivables compared to $35.7 million in 1997. See Note 5 "Sale of
Assets" of the Notes to Consolidated Financial Statements.

     Investing activities provided $123.4 million of cash inflow.  Cash
used by investing activities was $929.1 million in 1997 and $114.6 million
in 1996. In 1998 we received cash proceeds of $242.8 million from the sale-
leaseback of four real estate properties.  Excluding this, 1998 cash used
in investing activities was $119.4 million, which primarily reflects
capital expenditures, net of proceeds from disposal of property, plant and
equipment. This amount is slightly larger than in previous years due to the
addition of Coulter expenditures for a full year.  In 1997 investments and
acquisitions used $893.9 million primarily relating to the acquisition of
Coulter. An additional $39.6 million of cash proceeds were provided in 1997
through the sale and leaseback of instruments.  See Note 5 "Sale of Assets"
of the Notes to Consolidated Financial Statements.

     Financing activities used $130.0 million of cash flows as total debt
(including notes payable) was reduced $141.5 million.  This reflects a
substantial change from financing activity in 1997 when we reported a net
increase of $827.8 million in debt.  The increase in 1997 primarily
reflected the $1.2 billion borrowed to finance the Coulter acquisition, net
of any repayments.  Another significant change reflected in financing
activities is related to treasury stock purchases.  In 1997 and 1996 we
used $43.7 million and $35.9 million, respectively, to purchase treasury
stock.  In 1998, due to the level of outstanding debt and our efforts to
reduce those liabilities, we decided not to purchase any treasury stock.
Proceeds from sales of treasury stock and dividends to stockholders
increased slightly over the previous years.

     During the fourth quarter of 1997, we secured a new $1.3 billion
credit facility to finance the acquisition of Coulter.  See further
discussion of the credit facility and borrowing availability thereunder
and under the Company's other borrowing facilities in Note 7
"Debt Financing" of the Notes to Consolidated Financial Statements. 
The interest expense associated with the debt outstanding under the credit
facility creates an increased demand on future operating cash flows. 
Although we believe our consolidated operations will provide sufficient
cash flow in excess of anticipated operating requirements in order to
service the debt, we have implemented a plan to decrease the level of
outstanding borrowings more rapidly.   This ultimately is expected to
provide savings on the associated interest cost, partially offset by
increased rental expense as a result of any sale-leaseback transactions.

     Based upon current levels of operations and anticipated cost savings
and future growth, we believe our cash flow from operations, together with
available borrowings under the credit facility ($120.0 million as of
December 31, 1998) and other sources of liquidity (including leases, any
other available financing sources, and the proceeds of the planned asset
sales discussed previously), will be adequate to meet our anticipated
requirements for interest payments and other debt service obligations,
working capital, capital expenditures, lease payments and other operating
needs, until the maturity of the credit facility in 2002.  There can be no
assurance, however, that our business will continue to generate cash flow
at or above current levels or that estimated cost savings or growth can be
achieved.  Future operating performance and ability to service or refinance
existing indebtedness, including the credit facility, will be subject to
future economic conditions and to financial, business and other factors,
many of which are beyond our control.

Financial Risk Management:

     Our risk management program developed by senior management and
approved by the board, seeks to minimize the potential negative effects of
changes in foreign exchange rates and interest rates on the results of our
operations. Our primary exposures to market risk are due to foreign
exchange risk and interest rate risk.

     Foreign exchange risk arises from our exposure to fluctuations in
foreign currency exchange rates because our reporting currency is the U.S.
dollar and we derive approximately 50% of our sales by transacting business
in various foreign currencies. U.S. dollar-denominated costs and expenses
as a percentage of total operating costs and expenses are much greater
compared to U.S. dollar-denominated sales as a percentage of total net
sales.  As a result, appreciation of the U.S. dollar against our major
trading currencies has a negative impact on our results of operations, and
depreciation of the U.S. dollar against such currencies has a positive
impact.
     
     We seek to minimize the exposure to foreign currency fluctuations
through natural internal offsets to the fullest extent possible.  When
opportunities for natural internal offsets to our currency risk (arising
from both cash inflows and outflows denominated in the same currency) are
exhausted, we use derivative financial instruments to function as "hedges".
We use forward contracts, purchased option contracts, and complex option
contracts (consisting of purchased and sold options), to hedge transactions
with our foreign customers. Our policies do not permit us to use these
instruments for speculative or trading purposes.
     
     On January 1, 1999, the countries of the European Union adopted a
single currency known as the "euro".  The euro will, after January 1, 2002,
be the only official currency in the European Union countries.  Although
the effect of this conversion on the results of our operations may be
significant from a foreign currency or product pricing perspective, we are
unable to measure such impact at this time.  See details on the euro
conversion under "Euro - the new European currency".
     
     Our exposure to interest rate risk arises out of our long-term debt
obligations. We do not use derivative instruments to hedge our investment
portfolio, which consists of short-term investments (maturity of less than
a year).  Under the guidance of our risk management policies, we use
interest rate swap contracts on certain borrowing transactions. With the
aid of these contracts, we seek to reduce the interest rate risk by
changing the character of the interest rate on our long-term debt,
converting a variable rate to a fixed rate and vice versa.
     
     The Securities and Exchange Commission requires that registrants
include information about potential effects of changes in currency exchange
and interest rates in their financial statements.  Several alternatives,
all with some limitations, have been offered.  The following discussion is
based on sensitivity analysis, which models the effects of fluctuations in
currency exchange rates and interest rates.  This analysis is constrained
by several factors, including the following:
     
  -  the analysis is based on a single point in time; and
  -  the analysis does not include the effects of other complex market
     reactions that would arise from the changes modeled.

Although the results of the analysis may be useful as a benchmark, they
should not be viewed as forecasts.

     We estimated the sensitivity of the fair value of all derivative
foreign exchange contracts to hypothetical 10% strengthening and 10%
weakening of the spot exchange rates for the U.S. dollar against the
foreign currencies at December 31, 1998. The analysis showed that a 10%
strengthening of the U.S. dollar would result in a gain in fair value of
$30.5 million and a 10% weakening of the U.S. dollar would result in a loss
in fair value of $27.4 million in these instruments.  Losses and gains on
the underlying transactions being hedged would largely offset any gains and
losses on the fair value of derivative contracts.  These offsetting gains
and losses are not reflected in the above analysis.
     
     Similarly, we performed sensitivity analysis on the interest rate
sensitive instruments.  A one percentage point increase or decrease in
interest rates was estimated to decrease or increase next year's pre-tax
earnings by $4.9 million.
     
     For accounting treatments of these various hedge instruments, see
discussion under "Significant Accounting Policies".  For further discussion
of this topic, see Note 9 "Derivatives" of the Notes to Consolidated
Financial Statements.


Inflation:

     We continually monitor inflation and the effects of changing prices.
Inflation increases the cost of goods and services used. Competitive and
regulatory conditions in many markets restrict our ability to fully recover
the higher costs of acquired goods and services through price increases. We
attempt to mitigate the impact of inflation by implementing continuous
process improvement solutions to enhance productivity and efficiency and,
as a result, lower costs and operating expenses.  The effects of inflation
have, in our opinion, been managed appropriately and as a result have not
had a material impact on our operations and the resulting financial
position.

Environmental Matters:

     We are subject to federal, state, local and foreign environmental laws
and regulations. Although we continue to make expenditures for
environmental protection, we do not anticipate any significant expenditure
to comply with such laws and regulations that would have a material impact
on our results of operations, financial position or liquidity. We believe
our operations comply in all material respects with applicable federal,
state, and local environmental laws and regulations.
  
     To address contingent environmental costs, we establish reserves when
such costs are probable and can be reasonably estimated. Based on current
information and regulatory compliance (taking third party indemnities into
consideration), we believe we have established adequate reserves for
environmental expenditures.  We may incur additional costs that exceed the
reserves.  But based on current knowledge, we do not expect such amounts to
have a material impact on our results of operations, financial position, or
liquidity, although we do not give any assurance in this regard.  See
further discussion in Note 14 "Commitments and Contingencies" of the Notes
to Consolidated Financial Statements.

Litigation:

     We are currently, and are from time to time, subject to claims and
lawsuits arising in the ordinary course of our business, including those
relating to:
       -    intellectual property;
       -    contractual obligations;
       -    competition; and
       -    employment matters.

     In certain such actions, the plaintiffs may request punitive or other
damages or nonmonetary relief, which may not be covered by insurance.  If
granted, nonmonetary relief could materially affect the conduct of our
business.  We accrue for potential liabilities involved in these matters as
they become known and can be reasonably estimated.  In our opinion (taking
third party indemnities into consideration), the various asserted claims
and litigation in which we are currently involved are not reasonably likely
to have a material adverse effect on our business, results of operations,
financial position or liquidity.  However, we do not give any assurance as
to the ultimate outcome of such claims and litigation.  The resolution of
such claims and litigation could be material to our operating results for
any particular period, depending on the level of income for such period.
See further discussion of these matters in Note 14 "Commitments and
Contingencies" of the Notes to Consolidated Financial Statements.


Year 2000:

     We believe we have implemented a comprehensive Year 2000 program that
is on schedule for completion by the end of 1999, and that there will be no
material impact on our business, results of operations, financial position
or liquidity as a result of Year 2000 issues.

     
     Our Year 2000 program, implemented worldwide, is directed by our
senior management and includes six main projects:
     
     1.   products and services;
     2.   management information systems;
     3.   suppliers (materials and services);
     4.   engineering and manufacturing processes;
     5.   office equipment; and
     6.   facilities and utilities.

These projects generally include five phases:

     1.   inventory;
     2.   assessment;
     3.   remediation;
     4.   testing/validation; and
     5.   implementation.

The  following table is a summary of our Year 2000 program schedule target
dates (1):
<TABLE>
<CAPTION>
                                                      Testing/     Implement-
                  Inventory  Assessment  Remediation  Validation   ation
                  ---------  ----------  -----------  ----------   --------
  <S>             <C>        <C>         <C>          <C>          <C>
  Products &     
   services       Complete   Complete    Complete     Complete     Q1 1999
  Management                                                
   information
   systems        Complete   Complete    Q1 1999(3)   Q2 1999(3)   Q2 1999(3)
  Suppliers                                                 
   (materials   
   & services)    Complete   Complete    Q1 1999      Q1 1999      Q1 1999
  Engineering                                               
   &        
   manufacturing  Complete   Q1 1999     Q2 1999      Q3 1999      Q3 1999
  Office                                                    
   equipment      Complete   Q1 1999     Q2 1999      Q2 1999(3)   Q2 1999(3)
  Facilities      Complete   Q2 1999     Q2 1999      Q3 1999      Q3 1999(3)
   and
  Utilities       Complete   Q2 1999        (2)          (2)          (2)
</TABLE>
 
 (1)   The  target  dates are the ends of the quarters referred to.   For
       example Q1 1999 refers to the end of the first quarter of 1999.
 (2)   These  phases  will  not be performed for utilities,  but  will  be
       considered as part of the contingency planning.
 (3)   Revised target date.

     A number of our products include computer hardware and software,
including substantial custom software.  During 1998, we began providing our
customers information about the Year 2000 status of our products.  We
believe there are no significant Year 2000 product performance issues with
respect to products that we will continue to support after January 1, 2000.
We believe the impact to our business based on Year 2000 product
performance issues or litigation related to those issues will not be
material.  However, we cannot give any assurances to that effect until our
entire inventory, assessment, and remediation activities are completed.

     We believe our Year 2000 program will be completed on schedule.  But
the schedule is based on a number of factors and assumptions, such as:
  
     -    the accuracy and completeness of responses to our inquiries; and
     -    the availability of skilled personnel to complete the program.

The program schedule could be adversely impacted if any of the factors and
assumptions is incorrect.  We cannot give assurance that our Year 2000
program will be completed on schedule or that we will not uncover Year 2000
issues that could create a material impact on our performance.

     We do not believe that we have a material relationship with any single
third party supplier or customer.  Although a significant interruption in
our suppliers' and customers' activities (due to Year 2000 issues) is
unlikely, we could experience a material impact in our financial results if
such an interruption occurs.  Also, a portion of our revenues is indirectly
dependent upon our customers' reimbursement from federal, state, municipal
and foreign government agencies, and the state of readiness of those
government agencies is of concern.   At this time we believe the most
reasonably likely worst case scenario involves a significant interruption
in the ability of one or more government agencies to reimburse those
customers, which could lead to a significant interruption in cash received
from affected customers.  We are unable to estimate either the likelihood
or the potential cost of such an occurrence.
     
     We do not expect that the cost of our Year 2000 program will be
material to our business, results of operations, financial position or
liquidity. We anticipate that the total cost for our Year 2000 program
through 1999 will be approximately $9.0 million. Through December 31, 1998
we have spent approximately $3.8 million on our Year 2000 program. The
majority of these costs are for the remediation or replacement of
management information systems.  Most of the funding for our Year 2000
program is separately budgeted, but a portion of the funding is part of our
management information systems budget.  Year 2000 program funding has
delayed the implementation of certain other management information systems
changes, but this delay will have only a minor impact on managing the
Company.

     We are currently determining the extent to which contingency plans are
necessary for each aspect of our business with respect to Year 2000 issues
(including most reasonably likely worst case Year 2000 scenarios), and
intend to determine those contingency plans by the end of the first quarter
of 1999.

Euro - the new European currency:

     The countries of the European Union have adopted a single currency
known as the "euro".  The euro came into existence on January 1, 1999, and
is the official currency for the countries of the Economic and Monetary
Union (Austria, Belgium, Finland, France, Germany, Holland, Ireland, Italy,
Luxembourg, Portugal and Spain), with national currencies expressed as a
denomination (national currency units) of the euro.  During the three-year
transition period following its introduction, countries will be allowed to
transact business both in the euro and in their own currencies at fixed
exchange rates.  On January 1, 2002, the euro will be the only currency in
Economic and Monetary Union countries.

     We conduct business in more than 120 countries, generating
approximately 50% of revenues outside the United States.  A significant
portion of our business is conducted in Europe.  The introduction of the
euro requires that we make modifications to our internal operations as well
as to our external business arrangements.  For example, product pricing and
sales proposals are now available in the euro.  Similarly, our billing and
disbursement functions have been modified to reflect the use of the euro.

     Early in 1997, we established a six-member task force reporting to the
chief financial officer to identify the issues related to the introduction
of the euro and to develop and implement a plan to address those issues.
The task force has developed a detailed plan for the euro implementation
addressing all areas of operations, both internal and external. Major
initiatives resulting from the recommendations of the task force are:
     
     -    create a "Beckman Coulter Euro Information Center" to facilitate
          worldwide communication related to the euro;
     -    accommodate our customers' preferences for their national currency or
          the euro during the transition period;
     -    operate in a multi-currency environment (including the euro, national
          currency and the U.S. dollar), during the transition period, in
          all the European countries in which we do business; and
     -    adopt use of the euro for internal systems and reporting as of
          December 1, 2001.

     We do not expect the cost of this effort to have a material effect on
our business, results of operations, financial position or liquidity.
However, we cannot guarantee that all problems will be foreseen and
corrected, or that no material disruption of our business will occur.
There is also likely to be competitive implications on our pricing and
marketing strategies related to the conversion to the euro; however, we do
not know the effects of any such impact at this time.

Recent Accounting Developments:

     In June 1998, the Financial Accounting Standards Board issued
Statement of Financial Accounting Standards No. 133, "Accounting for
Derivative Instruments and Hedging Activities."  The provisions of the
statement require the recognition of all derivatives as either assets or
liabilities in the consolidated balance sheet and the measurement of those
instruments at fair value.  The accounting for changes in the fair value of
a derivative depends on the intended use of the derivative and the
resulting designation. This statement is effective for all fiscal quarters
of fiscal years beginning after June 15, 1999.  We are required to adopt
the statement in the first quarter of 2000.  We are studying the impact of
this pronouncement on our financial statements.  We have not yet determined
the impact on our results of operations.

     In 1998, the American Institute of Certified Public Accountants
("AICPA") issued Statement of Position 98-1, "Accounting for the Costs of
Computer Software Developed or Obtained for Internal Use", which provides
guidance concerning recognition and measurement of costs associated with
developing or acquiring software for internal use.  In 1998, the AICPA also
issued Statement of Position 98-5, "Reporting on the Costs of Start-Up
Activities", which provides guidance concerning the costs of start-up
activities.  For accounting purposes start-up activities are defined as one-
time activities related to opening a new facility, introducing a new
product or service, conducting business in a new territory or with a new
class of customer, initiating a new process in an existing facility, or
commencing some new operation.  Both pronouncements are effective for
financial statements of years beginning after December 15, 1998, with
earlier application encouraged.  We do not believe that adoption of these
pronouncements will have a material impact on our financial statements.

5.   Business Climate

     The clinical diagnostics and life science research markets are each
highly competitive and we encounter significant competition in each market
from many manufacturers, both domestic and outside the United States.
These markets continue to be unfavorably impacted by the economic weakness
in Europe and Asia and government cost containment initiatives in Europe as
well as healthcare cost containment in general.  The life science research
market also continues to be affected by consolidations of pharmaceutical
companies and governmental constraints on research and development
spending, especially outside the United States.

     In the clinical diagnostics market, attempts to lower costs and to
increase productivity have led to further consolidation among healthcare
providers in the United States, resulting in more powerful provider groups
that continue to leverage their purchasing power with suppliers to contain
costs.  Preferred supplier arrangements and combined purchases are becoming
more commonplace.  Consequently, it has become essential for manufacturers
to provide cost-effective diagnostic systems to remain competitive. Cost
containment initiatives in the United States and in the European healthcare
systems will continue to be factors, which may affect our ability to
maintain or increase sales.  Future profitability may also be adversely
affected if the relationship of the U.S. dollar to certain currencies is
maintained at the current levels or strengthened.

     Our new products originate from four sources:

     -    internal research and development programs;
     -    external collaborative efforts with individuals in academic
          institutions and technology companies;
     -    devices and techniques that are generated in customers' laboratories;
          and
     -    business and technology acquisitions.

     The continuing consolidation trend among United States healthcare
providers, mentioned previously, has increased pressure on diagnostic
equipment manufacturers to broaden their product offerings to encompass a
wider range of testing capability, greater automation and higher volume
capacity. Our acquisition of Coulter was a clear indicator of our resolve
to become a broad-based world leader in in-vitro diagnostic testing by
expanding our product offering.  Beckman Coulter is now the world's leading
manufacturer of hematology systems for the clinical analysis of blood
cells, where it has a market share twice the size of its next largest
competitor.  In addition, Beckman Coulter is considered a technology leader
in cell counting and characterization and has a number two position in flow
cytometry, which is used for both research and clinical applications.

The size and growth of our markets are influenced by a number of factors,
including:

     -    technological innovation in bio-analytical practice;
     -    government funding for basic and disease-related research (for
          example, heart disease, AIDS and cancer);
     -    research and development spending by biotechnology and pharmaceutical
          companies;
     -    healthcare spending; and
     -    physician practice.

     We expect worldwide healthcare expenditures and diagnostic testing to
increase over the long-term, primarily as a result of the following:

     -    growing demand for services generated by the aging of the world
          population;
     -    increasing expenditures on diseases requiring costly treatment (for
          example, AIDS and cancer); and
     -    expanding demand for improved healthcare services in developing
          countries.

     With Coulter and the two earlier acquisitions in immunochemistry-based
diagnostics, Hybritech, and the Access (Registered) immunoassay product line
of Sanofi, we completed a major strategic initiative intended to build on our
leadership position in automated clinical chemistry and create a broad
based capability in routine clinical chemistry.  We are able to offer
hospital laboratories worldwide a broad range of automated systems that
together can perform more than 75% of their test volume and essentially all
of the tests that are considered routine.  We believe we are able to
provide significant value added benefits, enhanced through our expertise in
simplifying and automating laboratory processes, to our customers.

6.   Taxes

     We are subject to taxation in many jurisdictions throughout the world.
Our effective tax rate and tax liability will be affected by a number of
factors, such as:

     -    the amount of taxable income in particular jurisdictions;
     -    the tax rate in such jurisdictions;
     -    tax treaties between jurisdictions;
     -    the extent to which income is repatriated; and
     -    future changes in the law.

     Generally, our tax liability in a particular jurisdiction is
determined either on an entity-by-entity (non-consolidated) basis or on a
consolidated basis including only those entities incorporated in the same
jurisdiction.  In those jurisdictions where consolidated tax reporting is
not permitted, we may pay income taxes even though on an overall basis we
may have incurred a net loss for the period.

7.  Forward Looking Statements

     This annual report contains forward-looking statements, including
statements regarding, among other items:
  
     -    our business strategy;
     -    anticipated trends in our business and plans to reduce indebtedness;
     -    our liquidity requirements and capital resources;
     -    anticipated proceeds from sales of assets; and
     -    the impact of Year 2000 issues, the euro conversion and inflation on
          our operations.

     These forward-looking statements are based on our expectations and are
subject to a number of risks and uncertainties, some of which are beyond
our control. These risks and uncertainties include, but are not limited to:
  
     -    complexity and uncertainty regarding development of new high-
          technology products;
     -    loss of market share through aggressive competition in the clinical
          diagnostics and life science research markets;
     -    our dependence on capital spending policies and government funding;
     -    the effect of potential health-care reforms;
     -    fluctuations in foreign exchange rates and interest rates;
     -    reliance on patents and other intellectual property;
     -    unanticipated reductions in cash flows and difficulty in sales of
          assets;
     -    unanticipated Year 2000 or euro problems; and
     -    other factors that cannot be identified at this time.

     Although we believe we have the product offerings and resources
required to achieve our objectives, actual results could differ materially
from those anticipated by these forward-looking statements. There can be no
assurance that events anticipated by these forward-looking statements will
in fact transpire as expected.
  
  
<PAGE>

BECKMAN COULTER, INC.
Consolidated Balance Sheets
In millions, except amounts per share

                                            December 31,
                                          1998        1997
                                          ----        ----
<TABLE>
<CAPTION>
<S>                                     <C>         <C>

Assets                                             
Current assets                                     
 Cash and equivalents                   $ 24.7      $ 33.1
 Short-term investments                    -           0.4
 Trade and other receivables             540.2       524.6
 Inventories                             302.8       332.3
 Deferred income taxes                    60.5        53.0
 Other current assets                     28.4        33.3
                                        ------      ------
  Total current assets                   956.6       976.7
Property, plant and equipment, net       309.4       410.9
Intangibles, less accumulated                      
 amortization
 of $24.6 in 1998 and $10.6 in 1997      419.1       444.9
Goodwill, less accumulated                         
 amortization of
 $14.9 in 1998 and $6.0 in 1997          356.1       402.8
Other assets                              92.1        95.7
                                      --------    --------
  Total assets                        $2,133.3    $2,331.0
                                      ========    ========
Liabilities and Stockholders' Equity               
Current liabilities                                
 Notes payable                        $  111.2    $   49.0
 Current maturities of long-term debt     23.9        19.9
 Accounts payable                         84.7        96.3
 Accrued compensation                     70.0        84.6
 Other accrued expenses                  368.3       575.5
 Income taxes                             61.2        69.6
                                      --------    -------- 
  Total current liabilities              719.3       894.9

Long-term debt, less current
 maturities                              982.2      1,181.3
Deferred income taxes                     42.8         40.3
Other liabilities                        262.1        132.7
                                      --------      ------- 
 Total liabilities                     2,006.4      2,249.2

Commitments and contingencies (see                 
Note 14)
Stockholders' equity                               
 Preferred stock, $0.10 par value;                 
  authorized 10.0 shares; none issued      -           -
 Common stock, $0.10 par value;                    
  authorized 75.0 shares; shares                      
  issued 29.1
  at 1998 and 1997;
  shares outstanding             
  28.4 at 1998 and
  27.6 at 1997                             2.9          2.9
 Additional paid-in capital              131.9        126.6
 Retained earnings                        35.4         19.0
 Accumulated other comprehensive loss:             
  Cumulative foreign currency
  translation adjustments                (13.9)       (13.8)                   
 Treasury stock, at cost                 (29.4)       (52.9)
                                      --------     --------
  Total stockholders' equity             126.9         81.8
                                      --------     --------
  Total liabilities                                
   and stockholders' equity           $2,133.3     $2,331.0
                                      ========     ========
</TABLE>
See accompanying notes to consolidated financial statements.

<PAGE>
BECKMAN COULTER, INC.
Consolidated Statements of Operations
In millions, except amounts per share
<TABLE>
<CAPTION>
                                       Years ended December 31,
                                       1998      1997       1996
                                       ----      ----       ----              
<S>                                <C>       <C>        <C>

Sales                              $1,718.2  $1,198.0   $1,028.0
Cost of sales                         920.6     609.7      477.8
                                   --------  --------   --------
Gross profit                          797.6     588.3      550.2
                                   --------  --------   --------           
Operating costs and expenses                              
                                                          
 Selling, general and  
 administrative                       492.3     360.3      319.3
 Research and development             171.4     123.6      108.4
 In-process research and
  development                           -       282.0        -
 Restructuring charge                  19.1      59.4        -
                                     ------    ------     ------
                                      682.8     825.3      427.7
                                     ------    ------     ------              
Operating income (loss)               114.8    (237.0)     122.5
                                                          
Nonoperating expense                                      
 Interest income                      (13.4)     (6.1)      (5.8)
 Interest expense                      87.8      29.4       18.1
 Other, net                            (6.2)     (8.4)      (1.3)
                                     ------    ------     ------
                                       68.2      14.9       11.0
                                     ------    ------     ------
Earnings (loss) before
 income taxes                          46.6    (251.9)     111.5
Income taxes                           13.1      12.5       36.8
                                     ------    ------     ------              
Net earnings (loss)                 $  33.5   $(264.4)   $  74.7
                                    =======   =======    =======              
Basic earnings (loss) per share     $  1.19   $ (9.58)   $  2.66
                                    =======   =======    =======               
Weighted average number 
 of shares outstanding                 28.0      27.6       28.0
                                    =======   =======    =======               
Diluted earnings (loss) per share   $  1.14   $ (9.58)   $  2.58
                                    =======   =======    =======
Weighted average number of shares                         
 and dilutive
 securities outstanding                29.3      27.6       28.9
                                    =======   =======    =======          

</TABLE>
See accompanying notes to consolidated financial statements.

<PAGE>
BECKMAN COULTER, INC.
Consolidated Statements of Stockholders' Equity
In millions, except amounts per share
<TABLE>
<CAPTION>
                                                         
                                           Accumula-        
                          Addi-            ted Other                 Total
                          tional           Compre-           Total   Compre-
                          Paid-            hensive           Stock-  hensive
                 Common   in      Retained (Loss)  Treasury  holders'Income
                 Stock    Capital Earnings Income  Stock     Equity  (Loss)
                 -----    ------- -------- ------  --------  ------  ------

<S>              <C>      <C>      <C>      <C>     <C>     <C>     <C>      
Stockholders'                                                            
 equity at   
 December
 31, 1995        $ 2.9    $ 129.0  $240.0  $ (1.5) $(22.5)  $347.9
                 =========================================================
Net earnings        -        -       74.7      -       -      74.7   $74.7
Foreign currency                                                         
 translation                                                             
 adjustments        -        -        -      (4.5)     -      (4.5)   (4.5)
Minimum pension                                                          
 liability          -        -        -       9.9      -       9.9     9.9
                 ---------------------------------------------------------
Comprehensive                                                            
 income for                                                               
 the year ended
 December 31,
 1996               -        -        74.7    5.4      -        -    $80.1
Dividends to                                                             
 stockholders,                                                    
 $0.52 per share    -        -       (14.7)    -       -     (14.7)
Purchases of                                                             
 treasury stock     -        -        -        -    (35.9)   (35.9)
Employee stock                                                           
 purchases          -      (0.1)      -        -     21.6     21.5   
                 -----------------------------------------------------------
Stockholders'                                                             
 equity at
 December
 31, 1996        $ 2.9   $ 128.9   $ 300.0  $  3.9 $(36.8)  $398.9
                 ===========================================================  
Net loss            -        -      (264.4)     -      -    (264.4) $(264.4)
Foreign currency                                                         
 translation                                                             
 adjustments        -        -        -      (17.7)    -     (17.7)   (17.7)
Comprehensive                                                            
loss for                                                                 
 the year ended 
 December 31,
 1997               -        -      (264.4)  (17.7)    -       -    $(282.1)
Dividends to                                                             
 stockholders,                                                           
 $0.60 per share    -        -       (16.6)    -       -     (16.6) 
Purchases of                                                             
 treasury stock     -        -        -        -     (43.7)  (43.7) 
Employee stock                                                           
 purchases          -      (2.3)      -        -      27.6    25.3  
                 ----------------------------------------------------------
Stockholders'                                                            
 equity at
 December 31, 
 1997            $ 2.9   $126.6     $ 19.0  $(13.8) $(52.9) $ 81.8
                 ==========================================================
Net earnings        -        -        33.5     -       -      33.5    $33.5
Foreign currency                                                         
 translation                                                             
 adjustments        -        -        -      (0.1)     -      (0.1)    (0.1)
                 ----------------------------------------------------------
Comprehensive                                                            
 income for                                                               
 the year ended
 December 31,
 1998               -        -        33.5   (0.1)      -      -      $33.4
Dividends to                                                             
 stockholders,                                                    
 $0.61 per share    -        -       (17.1)    -        -     (17.1)
Employee stock                                                           
 purchases          -        5.3      -        -      23.5     28.8
                 ---------------------------------------------------------
Stockholders'                                                            
 equity at 
 December 31,
 1998           $ 2.9     $131.9    $ 35.4 $(13.9)  $(29.4)  $126.9
                 ========================================================
</TABLE>
See accompanying notes to consolidated financial statements.

<PAGE>
BECKMAN COULTER, INC.
Consolidated Statements of Cash Flows
In millions 

                                                 Years ended December 31,
                                                1998        1997     1996
                                                ----        ----     ----
<TABLE>
<CAPTION>
<S>                                             <C>       <C>       <C>
Cash Flows from Operating Activities                      
 Net earnings (loss)                            $33.5     $(264.4)  $ 74.7
 Adjustments to reconcile net earnings (loss)             
  to net cash (used) provided by operating
  activities
    Depreciation and amortization               152.4       109.1     87.8
    Net deferred income taxes                    (5.0)       (5.1)    11.3
    Write-off of acquired in-process                      
     research and development                     -         282.0       -
 Proceeds from sale of sales-type                         
   lease receivables                              68.9       35.7       -
 Changes in assets and liabilities,                       
  net of acquisitions
    Trade and other receivables                  (58.3)     (53.1)   (26.1)
    Inventories                                   23.9       18.2    (26.4)
    Accounts payable and accrued   
     expenses                                   (191.0)      (3.4)    30.7
    Accrued restructuring costs                   (5.4)      44.4    (10.6)
    Accrued income taxes                          (8.4)       1.0      7.0
    Other                                        (12.4)     (26.6)    (9.3)
                                                ------     ------   ------
     Net cash (used) provided by                          
       operating activities                       (1.8)     137.8    139.1
                                                ------     ------   ------     
Cash Flows from Investing Activities                      
 Additions to property, plant and                         
  equipment                                     (165.2)    (100.9)  (110.5)
 Proceeds from sale-leaseback of                          
  instruments
  subject to customer leases                       -         39.6      -
 Proceeds from sale-leaseback of
  real estate                                    242.8        -        -
 Net disposals of property,
  plant and equipment                             45.4       18.4     18.7
 Sales of short-term investments                   0.4        7.7      0.2
 Investments and acquisitions                      -       (893.9)   (23.0)
                                                ------     ------   ------
     Net cash provided (used) by                          
      investing activites                        123.4     (929.1)  (114.6)
                                                ------     ------   ------     
Cash Flows from Financing Activities                      
 Dividends to stockholders                       (17.1)    (16.6)    (14.7)
 Proceeds from issuance of stock                  28.6      23.1      21.5
 Purchases of treasury stock                       -       (43.7)    (35.9)
 Net notes payable borrowings
 (reductions)                                     56.6      11.7      (2.4)
 Long-term debt borrowings                       411.0   1,164.2     128.3
 Long-term debt reductions                      (609.1)   (348.1)   (113.0)
                                                ------   -------     ------
     Net cash (used) provided by                            
      financing activities                      (130.0)    790.6     (16.2)
                                                ------   -------     ------
Effect of exchange rates on cash and
 equivalents                                      -         (0.8)      0.1
                                                ------   -------     ------   
(Decrease) increase in cash and
 equivalents                                      (8.4)     (1.5)      8.4
Cash and equivalents-beginning of 
 year                                             33.1      34.6      26.2
                                                ------   -------    ------
Cash and equivalents-end of year                $ 24.7    $ 33.1    $ 34.6
                                                ======   =======    ======
</TABLE>
                                                          
See accompanying notes to consolidated financial statements.

<TABLE>
<CAPTION>
Consolidated Statements of Cash Flows
In millions

                                        Years ended December 31,
                                        1998      1997      1996
                                        ----      ----      ----
<S>                                   <C>       <C>       <C>

Supplemental Disclosures of Cash Flow                     
Information
  Cash payments for interest          $ 88.4    $ 18.7    $ 18.3
  Cash payments for income taxes        21.5      12.9      19.2
Noncash Investing and                                     
  Financing Activities                                    
  Conversion of notes receivable        -         -          8.1
  Minimum pension liability             -         -         (9.9)
  Purchase of equipment under capital                     
   lease obligation                      9.7       9.8       6.9
  Issuance of Restricted Stock as                         
   employee compensation                 0.3       2.2       -
                                       -----     -----     -----
</TABLE>
See accompanying notes to consolidated financial statements.
<PAGE>

BECKMAN COULTER, INC.
Notes to Consolidated Financial Statements
Tabular dollar amounts in millions, except amounts per share


1. Nature of Business and Summary of Significant Accounting Policies

Nature of Business

     Beckman Coulter, Inc. is a world leader in providing systems that
simplify and automate laboratory processes.  We design, manufacture and
service a broad range of laboratory systems consisting of instruments,
reagents and related products that customers use to conduct basic
scientific research, drug discovery research and diagnostic analysis of
patient samples.  Approximately 80% of our 1998 sales were for clinical
diagnostics applications, principally in hospital laboratories, while the
remaining sales were for life science research applications (including drug
discovery) in universities, medical schools, and pharmaceutical and
biotechnology companies.

Principles of Consolidation

     The consolidated financial statements include the accounts of Beckman
Coulter, Inc., and its wholly owned subsidiaries.  The consolidated entity
is sometimes referred to as "the Company" in the accompanying consolidated
financial statements. All significant transactions among the consolidated
entities have been eliminated from the consolidated financial statements.
The financial statements include the assets and liabilities and the
operating results of all subsidiaries operating outside the U.S.  Balance
sheet amounts for these subsidiaries are as of November 30, 1998 and
November 30, 1997.  The operating results for the international
subsidiaries are for the twelve-month periods ending on those dates, except
as follows.  Coulter Corporation ("Coulter") was acquired October 31, 1997
and its results are included subsequent to that date.  However, in order to
be consistent with the way the Company reports its international results,
the reporting of Coulter's international results of operations has been
lagged by one month in 1998. Therefore, the results of 1998 include only
January through November sales and expenses for Coulter operations outside
the United States. The exclusion of one month's results for Coulter
international subsidiaries was not significant.

Use of Estimates

     In preparing the financial statements conforming to Generally Accepted
Accounting Principles ("GAAP"), we have made estimates and assumptions that
affect the following:
     
     -    reported amounts of assets and liabilities at the date of the
          financial statements;
     -    disclosure of contingent assets and liabilities at the date of the
          financial statements; and
     -    reported amounts of sales and expenses during the period.
     
Actual results could differ from those estimates.

Financial Instruments

     The carrying values of the Company's financial instruments approximate
their fair value at December 31, 1998 and 1997.  The market value of cash
and cash equivalents, trade and other receivables, other current assets,
investments, notes payable, accounts payable, and amounts included in other
accrued expenses meeting the definition of a financial instrument are based
upon management estimates.  Market values of the Company's debt and
derivative instruments are determined by quotes from financial
institutions.

Foreign Currency Translation

     Non-U.S. assets and liabilities are translated into U.S. dollars using
year-end exchange rates. Operating results are translated at exchange rates
prevailing during the year. The resulting translation adjustments are
accumulated as a separate component of stockholders' equity. Gains and
losses resulting from foreign currency hedging transactions and translation
adjustments relating to foreign entities deemed to be operating in U.S.
dollar functional currency or in highly inflationary economies are included
in the Consolidated Statements of Operations.

Derivatives

     We use derivative financial instruments to hedge only foreign currency
and interest rate market exposures of underlying assets, liabilities and
other obligations.  Our policy is:

  -    not to speculate in derivative instruments in order to profit from
       foreign currency exchange or interest rate fluctuations; and
  -    not to enter trades for which there are no underlying exposures.

    Instruments used as hedges must be effective at reducing the risk
associated with the exposure being hedged and are designated as a hedge
at the inception of the contract.  Accordingly, changes in market values
of hedge instruments are highly correlated with changes in market values
of underlying hedged items both at the inception of the hedge and over
the life of the hedge contract. See Note 9 "Derivatives" for accounting
treatment of derivative financial instruments.

Stock-Based Compensation

     In 1996 we implemented Statement of Financial Accounting Standards
No. 123, "Accounting for Stock-Based Compensation" ("SFAS 123").  As
permitted by SFAS 123, we continue to follow the guidance of Accounting
Principles Board Opinion No. 25, "Accounting for Stock Issued to
Employees."  Consequently, compensation related to stock options is the
difference between the grant price and the fair market value of the
underlying common shares at the grant date.  Generally, we issue options
to employees with a grant price equal to the market value of our common
stock on the grant date.  Accordingly, we have recognized no compensation
expense on our stock option plans.  We also do not recognize compensation
expense on stock issued to employees under our stock purchase plan, where
the discount from the market value is not material. As required by SFAS
123, we disclose in Note 12 "Employee Benefits", the pro forma effect on
earnings, as if compensation costs were recorded at the estimated fair
value of the stock options granted.

Cash and Equivalents

     Cash and equivalents include cash in banks, time deposits and
investments having maturities of three months or less from the date of
acquisition.

Short-term Investments

     Short-term investments are principally comprised of investments with
final maturities in excess of three months but less than one year from the
date of acquisition.

Inventories

     Inventories are valued at the lower of cost or market using the first-
in, first-out method.

Property, Plant and Equipment and Depreciation

     Land, buildings and machinery and equipment are carried at cost.  The
cost of additions and improvements are capitalized, while maintenance and
repairs are expensed as incurred.  Depreciation is computed generally on
the straight-line basis over the estimated useful lives of the related
assets.  Buildings are depreciated over 20 to 40 years, machinery and
equipment over 3 to 10 years and instruments subject to lease over the
lease terms but not in excess of 7 years.  Leasehold improvements are
amortized over the lesser of the life of the asset or the term of the lease
but not in excess of 20 years.

Goodwill and Other Intangibles

     Goodwill represents the excess of the purchase price of acquired
companies over the estimated fair value of the tangible and intangible net
assets acquired.  Goodwill is amortized on a straight-line basis over 40
years.  Other intangibles consist primarily of patents, trademarks and
customer base arising from business combinations.  Intangibles are
amortized on a straight-line basis over periods ranging from 15 to 30
years.

Accounting for Long-Lived Assets

     We adopted Statement of Financial Accounting Standards No. 121,
"Accounting for the Impairment of Long-Lived Assets and for Long-Lived
Assets to Be Disposed Of" ("SFAS 121") in 1996.  SFAS 121 establishes
accounting standards for the impairment of long-lived assets to be reviewed
whenever events or changes in circumstances indicate that the carrying
value of an asset may not be recoverable.  In addition, SFAS 121 requires
that certain long-lived assets be reported at the lower of carrying value
or the fair value less costs to sell.

Environmental Expenditures

     We accrue for environmental expenses resulting from existing
conditions that relate to operations when the costs are probable and
reasonable to estimate.

Revenue Recognition

     In general, revenue is recognized when a product is shipped.  Credit
is extended based upon the evaluation of the customer's financial condition
and generally does not require collateral.  When a customer enters into an
operating-type lease agreement, revenue is recognized over the life of the
lease.  Under a sales-type lease agreement, revenue is recognized at the
time of shipment with interest income recognized over the life of the
lease.  Service revenues are recognized ratably over the life of the
service agreement or as service is performed, if not under contract.

Research and Development

     Research and development costs are charged to operations as incurred.
In-process research and development is charged to operations in the period
acquired.

Nonoperating Income and Expenses

     Our nonoperating income and expenses are generally comprised of five
primary items:  (i) interest expense, (ii) interest income, (iii) foreign
exchange gains or losses, (iv) income (loss) from investments that are non-
core or are accounted for as a minority interest and (v) other nonoperating
gains or losses.  Interest income typically includes income from sales-type
leases and interest on cash equivalents and other investments.  Foreign
exchange gains or losses are primarily the result of our hedging activities
(net of revaluation) and are recorded net of premiums paid.  Other
nonoperating gains and losses are most frequently the result of one-time
items such as asset sales or other items.

Income Taxes

     We use the asset and liability method of accounting for income taxes.
Under the asset and liability method, deferred tax assets and liabilities
are recognized for the future tax consequences attributable to differences
between the financial statement carrying amounts of existing assets and
liabilities and their respective tax bases.  Deferred tax assets and
liabilities are measured using enacted tax rates expected to apply to
taxable income in the years in which those temporary differences are
expected to be recovered or settled.

Earnings (Loss) Per Share

     We adopted Statement of Financial Accounting Standards No. 128,
"Earnings Per Share" ("SFAS 128") in 1997.  SFAS 128 simplifies the
computation of earnings per share ("EPS") previously required in Accounting
Principles Board Opinion No. 15, "Earnings Per Share," ("APB 15") by
replacing primary and fully diluted EPS with basic and diluted EPS.  Under
SFAS 128, basic EPS is calculated by dividing net earnings (loss) by the
weighted-average common shares outstanding during the period.  Diluted EPS
reflects the potential dilution to basic EPS that could occur upon
conversion or exercise of securities, options, or other such items, to
common shares using the treasury stock method based upon the weighted-
average fair value of our common shares during the period.  Earnings per
share amounts for 1996 have been restated in accordance with SFAS 128.  See
Note 15 "Earnings (Loss) Per Share" for computation of EPS.

Comprehensive Income

     We adopted Statement of Financial Accounting Standards No. 130,
"Reporting Comprehensive Income" ("SFAS 130") in the first quarter of 1998.
SFAS 130 establishes standards for the reporting and display of
comprehensive income.  Components of comprehensive income include net
earnings (loss), foreign currency translation adjustments and changes in
minimum pension liability. The adoption of SFAS 130 required additional
disclosures but did not have a material effect on our financial position,
results of operations or liquidity.

Recent Accounting Developments

     In June 1998, the Financial Accounting Standards Board issued
Statement of Financial Accounting Standards No. 133, "Accounting for
Derivative Instruments and Hedging Activities."  The provisions of the
statement require the recognition of all derivatives as either assets or
liabilities in the Consolidated Balance Sheet and the measurement of those
instruments at fair value.  The accounting for changes in the fair value of
a derivative depends on the intended use of the derivative and the
resulting designation. This statement is effective for all fiscal quarters
of fiscal years beginning after June 15, 1999.  We are required to adopt
the statement in the first quarter of the year 2000.  We are studying the
impact of this pronouncement on our financial statements.  We have not yet
determined the impact on our results of operations.

     In 1998, the American Institute of Certified Public Accountants
("AICPA") issued Statement of Position 98-1, "Accounting for the Costs of
Computer Software Developed or Obtained for Internal Use", which provides
guidance concerning recognition and measurement of costs associated with
developing or acquiring software for internal use.  In 1998, the AICPA also
issued Statement of Position 98-5, "Reporting on the Costs of Start-Up
Activities", which provides guidance concerning the costs of start-up
activities.  For accounting purposes start-up activities are defined as one-
time activities related to opening a new facility, introducing a new
product or service, conducting business in a new territory or with a new
class of customer, initiating a new process in an existing facility, or
commencing some new operation.  Both pronouncements are effective for
financial statements of years beginning after December 15, 1998, with
earlier application encouraged.  We do not believe that adoption of these
pronouncements will have a material impact on our financial statements.

Reclassifications

     We made certain reclassifications to prior year amounts to conform to
the current year presentation.


2. Composition of Certain Financial Statement Captions
<TABLE>
<CAPTION>
                                          1998        1997
                                          ----        ----                  
<S>                                    <C>          <C>

Trade and other receivables                         
  Trade receivables                    $  488.9     $  488.5
  Other receivables                        50.2         30.0
  Current portion of lease receivables     21.8         23.5
  Less allowance for doubtful 
   receivables                            (20.7)       (17.4)
                                       --------     --------
                                       $  540.2     $  524.6
                                       ========     ========             
Inventories                                         
  Finished products                    $  183.2     $  206.5
  Raw materials, parts and assemblies      95.1         99.1
  Work in process                          24.5         26.7
                                       --------     --------                   
                                       $  302.8     $  332.3
                                       ========     ========

</TABLE>
2. Composition of Certain Financial Statement Captions (continuation from
   previous page)
<TABLE>
<CAPTION>
                                          1998        1997
                                          ----        ----
<S>                                    <C>        <C>     
  Property, plant and equipment, net                  
  Land                                 $   17.3   $   74.1
  Buildings                               142.7      240.2
  Machinery and equipment                 371.7      382.9
  Instruments subject to lease(a)         286.7      205.6
                                       --------   --------                     
                                          818.4      902.8
                                       --------   --------
Less accumulated depreciation                       
  Building, machinery and equipment      (330.7)    (365.4)
  Instruments subject to lease(a)        (178.3)    (126.5)
                                       --------   --------
                                       $  309.4   $  410.9
                                       ========   ========             
Other accrued expenses                              
  Accrued restructuring costs          $   41.6   $   47.0
  Unrealized service income                68.1       63.8
  Insurance                                18.9       27.2
  Accrued warranty and
    installation costs                     16.4       18.6
  Severance and related costs              58.0      109.6
  Closure of offices and manufacturing              
   facilities                               7.7       23.0
  Change in control payments               10.0       36.0
  Contractual obligations of Coulter        2.4      103.0
  Other                                   145.2      147.3
                                       --------   --------
                                       $  368.3   $  575.5
                                       ========   ========
</TABLE>

(a)   Includes  instruments leased to customers under three-  to  five-year
cancelable operating leases.


3.  Acquisitions

     We made no acquisitions in 1998.  During 1997 and 1996, we made
several acquisitions as discussed below, all of which were accounted for
using the purchase method of accounting.  The operating results of these
acquired businesses have been included in the Consolidated Statements of
Operations from the dates of acquisition.

     On October 31, 1997, we acquired all of the outstanding capital stock
of Coulter Corporation for $850.2 million, net of Coulter's cash on hand of
$24.8 million at the date of acquisition.  Coulter is the leading
manufacturer of in-vitro diagnostics systems for blood cell analysis.  The
purchase of Coulter was financed with the net proceeds from a new $1,300.0
million credit facility.  See Note 7 "Debt Financing".

     As a result of the acquisition, we originally recorded $374.4 million
in goodwill.  Goodwill reflects the excess of the purchase price and
purchase and assumed liabilities over the fair value of net identifiable
assets and in-process research and development projects acquired.  After
the final entries for purchase accounting were made in the fourth quarter
of 1998, we had reduced recorded goodwill by $35.7 million.  This reflects
changes in estimated purchase and assumed liabilities as well as changes in
values of acquired assets upon receipt of the final valuation analyses.
Other acquired intangibles amounted to $404.0 million, including $170.0
million attributable to the installed customer base acquired and $116.0
million of developed technology acquired.  Acquired in-process research and
development of $282.0 million was charged to expense in the fourth quarter
of 1997 in accordance with GAAP.  Purchase and assumed liabilities recorded
in 1997 totaled approximately $303.1 million.  These liabilities were
reduced by a net $17.1 million as a result of the finalization of purchase
accounting in 1998.

     Details of total purchase and assumed liabilities recorded and
activity in these accounts through December 31, 1998 are as follows:
<TABLE>
<CAPTION>

<S>                                 <C>
Balance at October 31, 1997         $303.1
                                    ======      
1997 activity:                            
Personnel                            (14.6)
Cancellations & dealer
 penalties                            (2.6)
                                     -----
Total 1997 activity                  (17.2)
                                    ======      
Balance at December 31,                   
1997:
Personnel                            195.4
Facility consolidations               14.0
Cancellations & dealer
 penalties                            11.8
Tax issues                            16.6
Other                                 48.1
                                     -----
Balance at December 31, 1997         285.9
                                     =====             
1998 activity(1) :                        
Personnel                           (125.0)
Facility consolidations               (6.3)
Cancellations & dealer   
 penalties                            (1.7)
Other                                (42.9)
                                     -----
Total 1998 activity                 (175.9)
                                     =====                 
Balance at December 31,                   
1998:
Personnel                             70.4
Facility consolidations                7.7
Cancellations & dealer 
 penalties                            10.1
Tax issues                            16.6
Other                                  5.2
                                     ------
Balance at December 31, 1998         $110.0
                                     ======
</TABLE>
                                      
 (1)1998 activity includes a reduction of $17.1 million, a result of the
finalization of purchase accounting entries.

     As our 1997 financial statements only include two months of operations
of Coulter, the following selected unaudited pro forma information is being
provided to present a summary of the combined results of Beckman and
Coulter as if the acquisition had occurred as of January 1, 1996, giving
effect to purchase accounting adjustments.  The unaudited pro forma data is
for informational purposes only and may not necessarily reflect the results
of operations of Beckman, had Coulter operated as part of the Company for
the years ended December 31, 1997 and 1996.
<TABLE>
<CAPTION>
                                   Pro Forma Years Ended
                            December 31, 1997 December 31, 1996
                            ----------------- -----------------
<S>                                <C>        <C>
Sales                              $1,790.1   $ 1,722.6
Net earnings                       $    9.9   $    29.8
Basic earnings per share           $    0.36  $     1.06
Diluted earnings per share         $    0.34  $     1.03
                                   ---------  ----------
</TABLE>

      The pro forma amounts reflect the results of operations for Beckman,
Coulter and the following purchase accounting adjustments for the periods
presented:

   -    amortization of intangible assets and goodwill based on the purchase
        price allocation for each period presented;
   -    amortization of debt financing fees and expenses over the term of the
        new credit facility;
   -    the  addition of interest expense on debt incurred to finance  the
        acquisition offset by a reduction of historical interest expense as
        a result of the elimination of Coulter's debt;
   -    additional cost of sales expense as a result of a step-up in the basis
        of inventory; and
   -    estimated income tax effect on the pro forma adjustments.

     The pro forma statements do not include the $282.0 million write-off
of in-process research and development and the $59.4 million accrued
restructuring costs, as they are non-recurring charges.  These charges are
included in the Consolidated Statements of Operations of the Company for
1997.  The pro forma diluted net earnings per share is based on our weighted
average number of common shares and dilutive common share equivalents during
1997 and 1996.

     In April 1997 we acquired the Access(R) immunoassay product line and
related manufacturing facility from Sanofi.  The acquisition also
established an ongoing alliance in immunochemistry between our Company and
Sanofi.  The Access(R) product line, together with the earlier acquisition of
Hybritech and our own immunochemistry/protein products, creates a major
presence for us in the field of immunochemistry.

     In December 1996 we acquired the assets and assumed the liabilities of
the laboratory robotics division of Sagian, Inc. of Indianapolis, Indiana.
By combining Sagian's scheduling software and robotics with our own bio-
robotics systems, we enhanced our ability to serve the pharmaceutical
industry's need for high-throughput screening ("HTS") of candidate
compounds for new drugs.

     In January 1996, we also acquired the assets and assumed the
liabilities of Hybritech, a San Diego-based life sciences and diagnostic
company.  The acquisition expanded our ability to develop and manufacture
high sensitivity immunoassays, including cancer tests.

     In May 1995, we initiated our acquisition of Genomyx Corporation of
Foster City, California.  Genomyx is a developer and manufacturer of
advanced DNA sequencing products and complements our biotechnology
business.  The acquisition was completed on October 21, 1996.

     With the exception of Coulter, the purchase prices of the acquisitions
and the effects on consolidated results of operations were not material to
the Company individually or in the aggregate.

4. Provision for Restructuring Operations

1998 Restructuring:

     We recorded a restructuring charge of $19.1 million, $11.2 million
after taxes, in the fourth quarter of 1998. This charge includes $13.3
million for personnel related and dealer termination costs. The work force
reductions anticipated under this plan, total approximately 75 positions in
Europe, Asia and North America in selling, general, administrative ("SG&A")
and technical functions and production related areas.   The $5.8 million
provided for facility consolidation and asset related write-offs includes
$2.4 million for lease termination payments, and $3.4 million for the write-
off of machinery, equipment and tooling associated with those functions to
be consolidated. The liability is included in "Other Accrued Expenses."
<TABLE>
<CAPTION>
                                              Facility        
                                             consolida-      
                                                tion           
                                  Personnel   and asset       
                                   & Other     related      Total
                                             write-offs
                                  ---------  ----------     -----
<S>                               <C>        <C>           <C>
Provision                                                
Consolidation of SG&A and                                
 technical functions              $ 10.1     $  -          $ 10.1
Changes in manufacturing
 operations                          3.2        5.8           9.0
                                  ------     ------        ------
Balance at December 31, 1998      $ 13.3     $  5.8        $ 19.1
                                  ======     ======        ======

Prior Restructurings:

     In the fourth quarter of 1997 we recorded a restructuring charge of
$59.4 million, $36.4 million after taxes.  This charge included $37.3
million for personnel related costs.  The work force reductions anticipated
under this plan, some of which occurred prior to the 1997 year-end totaled
approximately 500 positions in Europe, Asia and North America in selling,
general, administrative and technical functions and approximately 100
positions in production related areas.  The $22.1 million provided for
facility consolidation and asset related write-offs included $2.5 million
for lease termination payments, $12.2 million for the write-off of
machinery, equipment and tooling associated with those functions to be
consolidated, and $7.4 million for exiting non-core investment activities.
At December 31, 1998, our remaining obligation related to the prior
restructuring charges was $22.5 million, which is included in "Other
Accrued Expenses."

  The following table details the major components of the 1997
restructuring provision:

</TABLE>
<TABLE>
<CAPTION>
                                               Facility         
                                              consolida-       
                                                 tion            
                                   Personnel   and asset        
                                    & Other     related      Total
                                              write-offs
                                   ---------  ----------     -----
<S>                                 <C>        <C>          <C>
Provision
Consolidation of SG&A and                                   
 technical functions                $ 34.3     $ 18.2       $ 52.5
Changes in manufacturing
 operations                            3.0        3.9          6.9
                                    ------     ------       ------
Total provision                       37.3       22.1         59.4
                                    ======     ======       ======            
1997 activity
Consolidation of SG&A and                                  
 technical functions                  (7.8)      (5.0)       (12.8)
Changes in manufacturing
 operations                             -          -            -
                                    ------     ------       ------ 
Total 1997 activity                   (7.8)      (5.0)       (12.8)
                                    ======     ======       ======           
Balance at December 31, 1997
Consolidation of SG&A and                                  
 technical functions                  26.5       13.2         39.7
Changes in manufacturing
 operations                            3.0        3.9          6.9
                                    ------     ------       ------            
Balance at December 31, 1997          29.5       17.1         46.6
                                    ======     ======       ======
1998 Activity
Consolidation of SG&A and                                  
 technical functions                 (13.7)      (9.3)       (23.0)
Changes in manufacturing
 operations                           (1.1)         -         (1.1)
                                    ------     ------       ------
Total 1998 activity                  (14.8)      (9.3)       (24.1)
                                    ======     ======       ======           
Balance at December 31, 1998
Consolidation of SG&A and                                  
 technical functions                  12.8        3.9         16.7
Changes in manufacturing
 operations                            1.9        3.9          5.8
                                    ------     ------       ------
Balance at December 31, 1998        $ 14.7      $ 7.8       $ 22.5
                                    ======     ======       ======
</TABLE>

     In 1995, we also recorded a restructuring charge of approximately
$27.7 million.  This restructuring charge included costs for facility moves
and transition costs, which were anticipated and directly associated with
the 1993 restructuring plan but could not be recognized in establishment of
the original restructuring reserve under generally accepted accounting
principles.  At December 31, 1997, our remaining obligation relating to
this restructuring charge was $0.4 million, which was utilized in 1998.

5. Sale of Assets

     During 1998, we sold certain financial assets (primarily consisting of
customer lease receivables) as part of our plan to reduce debt and provide
funds for integration purposes.  The net book value of financial assets
sold was $67.7 million for which we received approximately $68.9 million in
cash proceeds.  

     In December 1997, we sold $34.2 million of Coulter's sales-type lease
receivables, net of allowances, for cash proceeds of $35.7 million.  Under
the provisions of Statement of Financial Accounting Standards No. 125,
"Accounting for Transfers and Servicing of Financial Assets and
Extinguishment of Liabilities" ("SFAS 125"), the 1998 and 1997 transactions
were accounted for as sales and as a result the related receivables have
been excluded from the accompanying Consolidated Balance Sheets.  The sales
are subject to certain recourse and servicing provisions and as such we
have established reserves for these potential exposures.

     Also in December 1997, we entered into an agreement for the sale and
leaseback of certain instruments, which are subject to various three- to
five-year cancelable operating-type leases to customers.  These instruments
had a net book value of $37.0 million and were sold for cash proceeds of
$39.6 million.  The gain is being deferred and credited to income, as a
rent expense adjustment over the lease term.  Obligations under the
operating lease agreements are included in Note 14 "Commitments and
Contingencies".

6. Sale-leaseback of Real Estate

     On June 25, 1998, we sold our interest in four of our properties:
Brea, California; Palo Alto, California; Chaska, Minnesota; and Miami,
Florida. At the same time, we entered into long-term ground leases for the
California and Minnesota properties and Coulter entered into a long-term
ground lease for the Miami property. At each of the properties (excluding
Miami), we conduct administrative, research and development, and
manufacturing activities.  At the Miami property, we conduct administrative
and research and development activities.  We expect to continue the same
type of activities at the properties as before the sale.

     The initial term of each of the leases is twenty years, with options
to renew for up to an additional thirty years. As provided by the leases,
we pay the rents in Japanese Yen. Annual rentals are approximately $17.9
million at current year-end rates. At the closing of the sale-leaseback
transaction, we became guarantor of a currency swap agreement between our
landlord and its banks to convert the Yen payments to U.S. dollars.  As
long as this swap agreement is in place, our obligation is to pay the rents
in Yen.  If this agreement ceases to exist, our obligation reverts to U.S.
dollar payments.  Coulter's rental payments are guaranteed by the Company.
We expect to pay the rents as they come due out of cash generated by
operations. Obligations under the operating lease agreements are included in
Note 14 "Commitments and Contingencies".
     
     The Palo Alto property is owned by Stanford University and we had
leased it under a long-term ground lease.  The Miami, Florida property was
formerly owned by Coulter. The buyers of all of the properties are not
affiliated with us. 

     The aggregate proceeds from the sale of the four properties (paid in
cash at closing) totaled $242.8 million before closing costs and
transaction expenses. In accordance with the accounting rules for
transactions in which a property is sold and immediately leased back from
the buyer (sale-leaseback), we have postponed recognizing the gains from
this transaction in our earnings and included it in "Other Liabilities".
The gain is being spread over the initial lease term of twenty years.
The remaining unrecognized gain was $130.1 million at December 31, 1998.
     
      Proceeds  from  the above transaction were used primarily  to  reduce
outstanding  borrowings under the $1,300.0 million  credit  facility.   See
Note 7 "Debt Financing".

7.   Debt Financing

      Notes payable consists primarily of short-term bank borrowings by our
subsidiaries  outside  the  U.S. under local  lines  of  credit.  The  bank
borrowings are at rates, which approximate current market rates; therefore,
the carrying value of the notes approximates the market value.  At December
31, 1998 approximately $65.7 million of unused uncommitted short-term lines
of  credit  were available to our subsidiaries outside the U.S. at  various
interest rates.  Within the U.S., $16.8 million in unused committed  short-
term lines of credit at market rates were available.  Compensating balances
and commitment fees on these lines of credit are not material and there are
no withdrawal restrictions.

Long-term debt consisted of the following at December 31:
<TABLE>
<CAPTION>
                             Average Rate              
                                  of
                               Interest       1998       1997
                               --------       ----       ----
<S>                              <C>       <C>       <C>
Senior Notes, unsecured, 
 due 2003                        7.10%     $ 160.0   $     -
Senior Notes, unsecured, 
 due 2008                        7.45%       240.0         -
Credit Agreement -                                     
  Term loan facility               -           -        400.0
Credit Agreement -                                     
  Revolving credit facility      5.90%       430.0      600.0
Debentures                       7.05%       100.0      100.0
Other long-term debt             5.33%        76.1      101.2
                                 -----       -----      -----
                                           1,006.1    1,201.2
Less current maturities                       23.9       19.9
                                           -------    -------
Long-term debt, less current                           
  maturities                               $ 982.2   $1,181.3
                                           =======   ========
</TABLE>

     In March 1998, we issued $160.0 million of 7.10% and $240.0 million of
7.45% unsecured Senior Notes due March 4, 2003 and 2008 (the "Senior
Notes"), respectively.  We used the net proceeds of $394.3 million to
reduce borrowings and commitments under our Credit Agreement.  Interest is
payable semi-annually in March and September. Discount and issuance costs
approximated $6.7 million which are being amortized to interest expense
over the term of the Senior Notes.  The Senior Notes may be redeemed in
whole or in part, at our option at any time at a redemption price equal to
the greater of:

  -    the principal amount of the Senior Notes; or
  -    the sum of the present values of the remaining scheduled payments of
       principal and interest thereon discounted to the redemption date on a
       semi-annual basis at a comparable treasury issue rate plus a margin
       of 0.25% for Senior Notes due 2003 and 0.375% for Senior Notes due 2008.

In connection with the issuance of the Senior Notes, certain of our
subsidiaries (the "Guarantor Subsidiaries") guaranteed such notes. See Note
8 "Guarantor Subsidiaries".

     In October 1997, in conjunction with the acquisition of Coulter, we
cancelled our $150.0 million credit agreement and entered into a new credit
agreement (the "Credit Agreement") with a group of financial institutions.
The Credit Agreement provides up to a maximum aggregate amount of $1,300.0
million through a $500.0 million senior unsecured term loan facility (the
"Term Loan") and an $800.0 million senior unsecured revolving credit
facility (the "Credit Facility"). Borrowings under the Credit Agreement
generally bear interest at current market rates plus a margin based upon
our senior unsecured debt rating or debt to earnings ratio, whichever is
more favorable.  We are, therefore, subject to fluctuations in such
interest rates, which could cause our interest expense to increase or
decrease in the future.  As a result of the substantial indebtedness
incurred in connection with the Coulter acquisition, our interest expense
will be higher and will have a much greater proportionate impact on net
earnings in comparison to pre-acquisition periods.  We must also pay a
quarterly facility fee of 0.25% per annum at December 31, 1998 on the
average Credit Facility commitment. The Credit Agreement requires mandatory
prepayment of the Term Loan and Credit Facility borrowings (and, to the
extent provided, reductions in commitments) thereunder from excess cash
flow (as defined in the Credit Agreement), and from proceeds of certain
equity or debt offerings, asset sales and extraordinary receipts.  The
Credit Facility, which matures in October 2002, is not subject to any
scheduled principal amortization. In addition, approximately $6.8 million
of fees paid to enter the Credit Agreement are being amortized to interest
expense over the term of the Credit Agreement. In March 1998, the Term Loan
was paid using the proceeds from the issuance of the Senior Notes and, in
June 1998, the Credit Facility was reduced using the proceeds obtained from
the sale-leaseback of real estate.  See Note 6 "Sale-leaseback of Real
Estate". In conjunction with these reductions in debt, we reduced the
Credit Agreement commitment from $1,300.0 million to $550.0 million by June
1998.  As required by GAAP, the write-off of the fees paid to enter the
Credit Agreement has been accelerated.  The unamortized fees at December
31, 1998 are $2.3 million. As of December 31, 1998, the Company's remaining
borrowing availability under the Credit Facility is $120.0 million.
Amounts not drawn under the Credit Facility will be available to meet future
working capital and other business needs of the Company.

     In June 1996, we issued $100.0 million of debentures bearing an
interest rate of 7.05% per annum due June 1, 2026.  Interest is payable
semi-annually in June and December. Discount and issuance costs of
approximately $1.5 million are being amortized to interest expense over the
term of the debentures.  The debentures may be repaid on June 1, 2006 at
the option of the holders of the debentures.  In March 1998, the debenture
agreement was amended to increase the June 1, 2006 redemption price to
103.9% of the principal amount, together with accrued interest to June 1,
2006.  The debentures may be redeemed, in whole or in part, at our option
at any time after June 1, 2006, at a redemption price equal to the greater
of:

  -    the principal amount of the debentures; or
  -    the sum of the present values of the remaining scheduled payments of
       principal and interest thereon discounted to the redemption date
       on a semi-annual basis at a comparable treasury issue rate plus
       a margin of 0.1%.

     Other long-term debt at December 31, 1998 consists principally of
$58.9 million of notes used to fund the operations of our international
subsidiaries and notes given as partial consideration for an acquisition.
Some of the notes issued by our international subsidiaries are secured by
their assets.  Notes used to fund our international subsidiaries amounted
to $76.6 million at December 31, 1997.  Capitalized leases of $17.2 million
in 1998 and $24.6 million in 1997 are also included in other long-term
debt.

     Certain of our borrowing agreements contain covenants that we must
comply with, for example: minimum net worth, maximum capital expenditures,
a debt to earnings ratio, a minimum interest coverage ratio and a maximum
amount of debt incurrence.  At December 31, 1998, the Company was in
compliance with all such covenants.

     The aggregate maturities of long-term debt for the five years
subsequent to December 31, 1998 are $23.9 million in 1999, $13.7 million in
2000, $8.6 million in 2001, $435.5 million in 2002, $173.7 million in 2003
and $350.7 million thereafter.

8.   Guarantor Subsidiaries

     We present below the supplemental condensed financial information of
the Company, Guarantor Subsidiaries and Non-Guarantor Subsidiaries.  Please
note that in this footnote, we used the equity method of accounting for our
investments in subsidiaries and the Guarantor Subsidiaries' investments in
Non-Guarantor Subsidiaries.  This supplemental financial information should
be read in conjunction with the Consolidated Financial Statements.
<TABLE>
<CAPTION>
                                                         
                                          Non-            
                                Guarantor Guarantor                
                                Subsi-    Subsi-    Elimina-  Consoli-
                       Parent   diaries   diaries   tions     dated
                       ------   -------   -------   -------   --------
<S>                   <C>      <C>         <C>     <C>        <C>
Condensed Consolidated                                        
Balance Sheet                                                 
December 31, 1998
                                                              
Assets:                                                       
  Cash and equivalents $   4.2  $  (0.1)   $  20.6  $   -     $  24.7
  Trade and                                                   
    other receivables    199.9     50.4      289.9      -        540.2
  Inventories            146.5     52.6      134.6     (30.9)    302.8
  Other current assets   149.0    396.4       86.7    (543.2)     88.9
                         -----    -----      -----     -----     -----
    Total current 
     assets              499.6    499.3      531.8    (574.1)    956.6
                                                              
  Property, plant and                                         
   equipment, net        120.7     89.1      156.3     (56.7)    309.4
  Intangibles, net        33.0    384.8        1.3       -       419.1
  Goodwill, net           15.0    329.5       11.6       -       356.1
  Other long-term                 
    assets             1,357.1    176.0      253.2  (1,694.2)     92.1
                       -------   ------    -------  --------   -------
     Total assets     $2,025.4 $1,478.7    $ 954.2 $(2,325.0) $2,133.3
                                                              
Liabilities:                                                  
  Notes payable and                                           
   Current maturities                                         
   of long-term debt  $   19.6 $    2.6    $ 112.9 $     -    $  135.1
  Accounts payable
   and                                        
   Accrued expenses      219.5    199.7      103.8       -       523.0
  Other current                                               
    Liabilities          176.0    323.9       83.2    (521.9)     61.2
                      --------   ------    -------   -------    ------ 
     Total current                                            
      liabilities        415.1    526.2      299.9    (521.9)    719.3
  Long-term debt,
   less current
   maturities            950.8      0.8       30.6      -        982.2
  Other long-term                                             
    Liabilities          532.6    279.6      214.4    (721.7)    304.9
                      --------   ------    -------   -------    ------
    Total liabilities  1,898.5    806.6      544.9  (1,243.6)  2,006.4
 Total stockholders'
  equity                 126.9    672.1      409.3  (1,081.4)    126.9  
                       -------   ------    -------   -------    ------

 Total                                                   
  liabilities and
  Stockholders'
  equity              $2,025.4 $1,478.7    $ 954.2 $(2,325.0) $2,133.3
                      ======== ========    ======= ========== ========
</TABLE>
<TABLE>
<CAPTION>
                                          Non-            
                                Guarantor Guarantor Elimina-  Consoli-
                       Parent   Subsi-    Subsi-    tions     dated
                                diaries   diaries
Condensed Consolidated
Balance Sheet                                                 
December 31, 1997
<S>                <C>           <C>          <C>     <C>          <C>
Assets:                                                       
  Cash and
   equivalents     $    13.9     $    7.3     $  11.9 $      -      $  33.1
  Marketable
   securities             -            -          0.4        -          0.4
  Trade and                                                   
   other
   receivables         131.7         95.4       297.5        -        524.6
  Inventories          127.8         98.7       136.5     (30.7)      332.3
  Other
   current
   assets              160.2        165.1        98.1    (337.1)       86.3
                       -----        -----        ----     -----       -----
    Total
    current
    assets             433.6        366.5       544.4    (367.8)      976.7
                                                              
  Property, plant
   and equipment,                                   
   net                 133.8        125.1       152.0       -         410.9
  Intangibles, net      28.5        401.5        14.9       -         444.9
  Goodwill, net          5.6        397.0         0.2       -         402.8
  Other long-term
   assets            1,112.4        208.0       196.5  (1,421.2)       95.7    
                     -------        -----       -----   -------       -----    
  Total assets      $1,713.9     $1,498.1      $908.0 $(1,789.0)   $2,331.0
                     =======      =======       =====   =======     =======   
Liabilities:                                                  
  Notes payable
   and current
   maturities of                                           
   long-term
   debt                $7.7          $7.3       $53.9     $ -         $68.9
  Accounts
   payable and                                        
   accrued expenses   207.8         408.1       140.5       -         756.4
  Other current                                                
   liabilities        114.0           2.7       126.0    (173.1)       69.6
                      -----         -----       -----     -----       -----
    Total current                                             
     liabilities      329.5         418.1       320.4    (173.1)      894.9
  Long-term debt,
   less current
   maturities       1,122.9           4.6        53.8      -        1,181.3
  Other long-term                                             
   liabilities        179.7         346.0       155.4    (508.1)      173.0
                      -----         -----       -----    ------     ------- 
    Total
     liabilities    1,632.1         768.7       529.6    (681.2)    2,249.2
 Total
  stockholders'
  equity               81.8         729.4       378.4  (1,107.8)       81.8
                     ------         -----       -----   -------     -------
Total liabilities
  and                                         
  stockholders'
  equity           $1,713.9      $1,498.1      $908.0 $(1,789.0)   $2,331.0
                   ========      ========      ======  ========     =======
</TABLE>
<TABLE>
<CAPTION>
                                                               
                                          Non-                 
                               Guarantor  Guarantor            
                               Subsi-     Subsi-    Elimina-   Consoli-
                       Parent  diaries    diaries   tions      dated
                       ------  -------    -------   ------     -----

Condensed Consolidated                                         
Statement of Operations                                                   
Year Ended December 31, 1998
                                                               
<S>                    <C>     <C>        <C>       <C>        <C>
Sales                  $609.2  $446.0     $1,156.3  $(493.3)   $1,718.2
Operating costs and                                            
  expenses:
  Cost of sales         295.3   226.4        890.2   (491.3)      920.6
  Selling, general
   and                                         
   administrative       181.4   114.5        196.4       -        492.3
  Research and  
   development           96.2    71.2          4.0       -        171.4
  Restructuring charge   19.1     -             -        -         19.1
                         ----    ----         ----     -----      -----
Operating income         17.2    33.9         65.7     (2.0)      114.8
Nonoperating (income) 
 expense                (36.1)  (19.1)        13.7     109.7       68.2
                         ----    ----         ----     -----      -----
Earnings (loss) before                                         
  income taxes           53.3    53.0         52.0    (111.7)      46.6
                                                               
Income taxes              4.6     6.6          1.9       -         13.1
                         ----    ----         ----     -----      -----
Net earnings(loss)     $ 48.7  $ 46.4       $ 50.1   $(111.7)   $  33.5
                                                               
</TABLE>
<TABLE>
<CAPTION>
                                          Non-                 
                               Guarantor  Guarantor            
                               Subsi-     Subsi-    Elimina-   Consoli-
                       Parent  diaries    diaries   tions      dated
                       ------  -------    -------   -------    -------
Condensed Consolidated
Statement of Operations                                                   
Year ended December 31, 1997

<S>                   <C>      <C>         <C>       <C>        <C>
Sales                 $ 513.9  $ 150.9     $1,069.5  $(536.3)   $1,198.0
Operating costs and                                            
  expenses:
  Cost of sales         214.2    106.3        798.5   (509.3)      609.7
  Selling, general and                                         
   administrative       154.5     39.0        166.8      -         360.3
  Research and
   development           87.6     33.8          2.2      -         123.6
  In-process
   research                                          
   and 
   development           -       282.0          -        -         282.0
  Restructuring
    charge               59.4      -            -        -          59.4
                         ----    -----       ------    -----       -----
Operating income
 (loss)                  (1.8)  (310.2)       102.0     (27.0)    (237.0)
Nonoperating
 expense
 income                 233.2     (8.8)        (0.7)   (208.8)      14.9
                        -----     ----        -----    ------      -----
(Loss) earnings
 before income
 taxes                 (235.0)  (301.4)       102.7     181.8     (251.9)
Income taxes
 (benefit)                8.6      2.0          8.1      (6.2)      12.5
                        -----    -----        -----    ------      -----
Net (loss) earnings   $(243.6) $(303.4)       $94.6    $188.0   $ (264.4)
</TABLE>
<TABLE>
<CAPTION>

                                          Non-                 
                               Guarantor  Guarantor            
                               Subsi-     Subsi-    Elimina-   Consoli-
                       Parent  diaries    diaries   tions      dated
                       ------  -------    -------   -------    -------
Condensed Consolidated
Statement of Operations                                                   
Year ended December 31, 1996

<S>                    <C>     <C>        <C>       <C>        <C>
Sales                  $457.4  $112.8     $772.7    $(314.9)   $1,028.0
Operating costs and                                            
  expenses:
  Cost of sales         184.9    33.7      569.3     (310.1)      477.8
  Selling, general
   and                                         
   administrative       147.1    21.4      150.8         -        319.3
  Research and
   development           91.1    17.1        0.2         -        108.4
                       ------   -----     ------     ------     -------
Operating income         34.3    40.6       52.4       (4.8)      122.5
Nonoperating
 (income)
 expense                (64.9)   (1.8)       0.2       77.5        11.0
                       ------   -----     ------     ------     -------
Earnings (loss)
 before
 income
 taxes                   99.2    42.4       52.2      (82.3)      111.5
Income taxes             18.1     5.3       10.2        3.2        36.8
                       ------   -----     ------     ------     -------
Net earnings (loss)    $ 81.1   $37.1      $42.0     $(85.5)     $ 74.7
                       ======   =====     ======     ======     =======
</TABLE>
<TABLE>
<CAPTION>
                                          Non-                 
                               Guarantor  Guarantor            
                               Subsi-     Subsi-    Elimina-   Consoli-
                       Parent  diaries    diaries   tions      dated
                       ------  -------    -------   --------   -------
Condensed Consolidated
Statement of Cash Flows
Year ended December 31, 1998

<S>                  <C>       <C>       <C>       <C>         <C>
Net cash provided                                                
 (used) 
 by operating
 activities          $(23.2)   $(85.3)   $ 106.7   $  -        $ (1.8)
Cash flows from                                                
 investing
 activities:
Additions to
 property,                                         
 plant and
 equipment            (84.5)    (11.0)     (69.7)     -        (165.2)
Net disposals of                                               
 property, 
 plant and
 equipment              2.0        -        43.4      -          45.4
Sale of short-term                                             
  investments            -         -         0.4      -           0.4
Proceeds from sale-                                            
  leaseback of
  real estate         186.1        -         -      56.7        242.8
                      -----     -----      -----    ----        -----
Net cash provided                                              
 (used)
 by investing
 activities           103.6    (11.0)     (25.9)    56.7        123.4
                                                               
Cash flows from                                                
financing
  activities:
Dividends to
 stockholders         (17.1)       -         -       -          (17.1)
Proceeds from
 issuance                                         
 of stock              28.6        -         -       -           28.6
Notes payable 
 borrowings            11.4        -       45.2      -           56.6
Net intercompany                                               
 borrowings 
 (reductions)          59.2     93.8      (96.3)    (56.7)         -
Long-term debt                                                 
 (reductions)   
 borrowings          (172.2)    (4.9)     (21.0)     -         (198.1)
                      -----     ----       ----      -----      -----
Net cash (used)                                                
 provided
 by financing
 activities           (90.1)    88.9      (72.1)    (56.7)     (130.0)
                      -----     ----       ----      -----      -----         
(Decrease)
 increase in                                         
 cash and
 equivalents           (9.7)    (7.4)       8.7      -           (8.4)
Cash and
 equivalents -                                         
 beginning of
 year                  13.9      7.3       11.9      -           33.1
                      -----     ----       ----     ------      -----
Cash and
 equivalents -                                         
 end of year          $ 4.2    $(0.1)    $ 20.6    $ -         $ 24.7
</TABLE>
<TABLE>
<CAPTION>


                                          Non-                 
                               Guarantor  Guarantor            
                               Subsi-     Subsi-    Elimina-   Consoli-
                       Parent  diaries    diaries   tions      dated
                       ------  -------    -------   -------    -------
Condensed Consolidated
Statement of Cash Flows
Year ended December 31, 1997

<S>                    <C>       <C>       <C>      <C>        <C>
Net cash
 provided                                              
 (used)  
 by operating
 activities            $  4.2    $ 35.9     $169.5   $ -       $ 137.8
Cash flows from                                                
 investing
 activities:
Additions to
 property,                                         
 plant and
 equipment              (65.9)    (11.6)     (23.4)   -         (100.9)
Net disposals of                                               
 property,
 plant and
 equipment               12.0       5.4        1.0    -           18.4
Sale of
 short-term                                             
 investments               -        7.7         -     -            7.7
Proceeds from sale-                                            
 leaseback 
 transactions            39.6        -          -     -           39.6
Investments and
 acquisitions          (893.9)       -          -     -         (893.9)
                        -----      ----       ----    ---        -----
Net cash (used)                                                
 provided 
 by investing
 activities            (908.2)      1.5      (22.4)   -         (929.1)
Cash flows from                                                
 financing
 activities:
Dividends to
 stockholders           (16.6)       -          -     -          (16.6)
Proceeds from
 issuance                                         
 of stock                23.1        -          -     -           23.1
Purchases of
 treasury
 stock                  (43.7)       -          -     -          (43.7)
Notes payable                                                  
 (reductions)
 borrowings              (3.5)       -        15.2    -           11.7
Net intercompany                                               
 (reductions)
 borrowings             (39.8)     78.2      (38.4)   -             -
Long-term debt                                                 
 borrowings
 (reductions)            970.5    (39.1)    (115.3)   -           816.1
                         -----     ----      -----   -----       ------
Net cash (used)                                                
 provided 
 by
 financing
 activities              890.0     39.1     (138.5)   -           790.6
                                                               
Effect of exchange                                             
 rates 
 on cash and
 equivalents              -         -         (0.8)   -           (0.8)
                         -----     ----      -----   -----       ----- 
(Decrease)
 increase in                                         
 cash and
 equivalents             (14.0)    4.7         7.8    -           (1.5)
Cash and
 equivalents -                                         
 beginning of year        27.9     2.6        4.1     -           34.6
                         -----    ----       ----    -----       -----
 Cash and
 equivalents -                                         
 end of year            $ 13.9   $ 7.3     $ 11.9   $ -         $ 33.1
                        ======   =====     ======   ======      ======        
</TABLE>
<TABLE>
<CAPTION>
                                          Non-                 
                               Guarantor  Guarantor            
                               Subsi-     Subsi-    Elimina-   Consoli-
                       Parent  diaries    diaries   tions      dated
Condensed Consolidated
Statement of Cash Flows
Year ended December 31, 1996

<S>                     <C>     <C>        <C>       <C>       <C>
Net cash
 provided                                              
 (used)
 by operating
 activities             $186.5  $ 32.3     $ (79.7)  $   -     $ 139.1
Cash flows from                                                
investing
 activities:
   Additions to                                                
   property,
   plant and
   equipment             (44.1)  (9.7)      (56.7)       -      (110.5)
   Net disposals of                                            
   property, 
   plant and
   equipment              11.8    0.4         6.5        -        18.7
   Sale of short-term                                          
    investments            0.2     -           -         -         0.2
   Investments and
    acquisition          (38.0)    -         15.0        -       (23.0)
                          ----    ----       ----      ----       ----
   Net cash (used)                                           
    provided 
    by investing
    activities           (70.1)  (9.3)      (35.2)       -      (114.6)
Cash flows from                                                
  financing
  activities:
  Dividends to 
   stockholders          (14.7)    -          -          -       (14.7)
   Proceeds from                                               
   issuance
   of stock               21.5     -          -          -        21.5
   Purchases of                                                
    treasury
    stock                (35.9)    -          -          -       (35.9)
   Notes payable                                               
   (reductions)    
   borrowings             (5.9)    -          3.5        -        (2.4)
   Net intercompany                                            
   (reductions)
   borrowings            (61.9)  (39.6)     101.5        -          -
   Long-term debt                                              
   borrowings 
   (reductions)            8.0     0.3        7.0        -        15.3
                          ----    ----      -----       ----      ----
     Net cash
     (used)                                           
     provided 
     by financing
     activities          (88.9)  (39.3)     112.0        -       (16.2)
Effect of exchange                                             
  rates 
  on cash and              -        -         0.1        -         0.1
                          ----    ----      -----       ----      ----
Increase
 (decrease) in
  cash and
  equivalents             27.5   (16.3)     (2.8)        -         8.4
Cash and
 equivalents -                                         
 beginning of year         0.4    18.9       6.9         -        26.2
                         -----    ----     -----        ----      ----      
Cash and equivalents -                                         
  end of year           $ 27.9  $  2.6     $ 4.1      $  -      $ 34.6
                                                               
</TABLE>

9.   Derivatives

      We manufacture our products principally in the United States, but  we
generate  approximately half of our revenues from sales  made  outside  the
U.S.   by   our  international  subsidiaries.   Sales  generated   by   the
international  subsidiaries generally are denominated in  the  subsidiary's
local  currency,  thereby  exposing us to  the  risk  of  foreign  currency
fluctuations. Additionally, as a net borrower, we are exposed to  the  risk
of fluctuating interest rates.

     Various  foreign currency contracts are used to hedge firm commitments
denominated in foreign currencies and to mitigate the impact of changes  in
foreign  currency  exchange  rates  on  our  operations.  Foreign  currency
contracts  used include forward contracts, purchased option contracts,  and
complex  option  contracts, consisting of purchased and sold  options.  The
hedge  instruments  mature at various dates approximating  the  transaction
dates.   The  table  below  summarizes the notional  amounts  of  contracts
afforded hedge accounting treatment at December 31:

                                   Notional Amount*
                                   1998       1997
                                   ----       ----
Forward Contracts                  $196.6     $66.9
Purchased Option Contracts         158.8      45.0
Complex Option Contracts           12.0       28.5
                                              

*  Notional  amounts  represent the amounts  of  the  items  on  which  the
contracts are based and not the actual amounts exchanged by the parties.

      When  we  use  foreign currency contracts and the dollar  strengthens
against  foreign  currencies, the decline in the value  of  future  foreign
currency cash flows is partially offset by the recognition of gains in  the
value  of  the  foreign  currency contracts designated  as  hedges  of  the
transactions.   Conversely, when the dollar weakens, the  increase  in  the
value of future foreign currency cash flows is reduced by:

     -    the recognition of the net premium paid to acquire option contracts;
     -    the recognition of any loss in the value of the forward contracts
          designated as hedges of the transactions; and
     -    the recognition of any loss on sold options.

Market  value  gains  and  losses  and  premiums  on  these  contracts  are
recognized in "Other, net nonoperating expense" when the hedged transaction
is recognized.  The net premiums paid for purchased and complex options are
reported in current assets.

      At  December  31, 1998, we held no purchased foreign currency  call
option  contracts.   At  December 31, 1997,  we  held  purchased  foreign
currency  call  option contracts totaling $20.4 million,  which  did  not
qualify  for hedge accounting treatment.  The call options were purchased
to  create  synthetic puts when combined with forward and complex  option
contracts,  thereby  cost effectively reducing the Company's  risk.   The
purchased  call  options matured at various dates  throughout  1998  with
resulting  gains  recognized  at  maturity.   Premiums  paid  for   these
contracts   are  recognized  immediately  in  "Other,  net   nonoperating
expense".

      We  also use foreign currency swap contracts to hedge loans  between
subsidiaries.   At  December  31,  1998,  we  had  foreign  currency  swap
contracts  totaling $138.8 million expiring at various dates  through  May
1999.   At  December  31,  1997, the Company  had  foreign  currency  swap
contracts totaling $103.7 million.  As monetary assets and liabilities are
marked to market and recorded in earnings, foreign currency swap contracts
designated  as  hedges  of the monetary assets and  liabilities  are  also
marked  to market with the resulting gains and losses similarly recognized
in  earnings.   Gains  and losses on foreign currency swap  contracts  are
included in "Other, net nonoperating expense" and offset losses and  gains
on  the  hedged  monetary assets and liabilities.  The carrying  value  of
foreign  currency swap contracts is reported in current assets and current
liabilities.

      We  occasionally use foreign currency contracts to hedge  the  market
risk  of  a subsidiary's net asset position. At December 31, 1998,  we  had
$22.5  million  foreign currency contracts related to net asset  positions.
At  December 31, 1997, we had no foreign currency contracts related to  net
asset  positions. Foreign currency contracts resulted in favorable  foreign
currency  translation  adjustments of $2.5  million  and  $1.5  million  at
December 31, 1998 and 1997, respectively. Market value gains and losses  on
foreign  currency contracts used to hedge the market risk of a subsidiary's
net  asset  position  are  recognized in "Accumulated  Other  Comprehensive
Income" as translation gains and losses are reflected in the balance sheet.
The foreign currency translation adjustments are only recognized in "Other,
net nonoperating expense" upon liquidation of the subsidiary.
  
     We use interest rate contracts on certain borrowing transactions to hedge
fluctuating interest rates.  Interest rate contracts are intended to be an
integral part of borrowing transactions and, therefore, are not recognized at
fair value.  Interest differentials paid or received under these contracts are
recognized as adjustments to the effective yield of the underlying financial
instruments hedged.  Interest rate contracts would only be recognized at fair
value if the hedged relationship were terminated.  Gains or losses accumulated
prior to termination of the hedged relationship are amortized as a yield
adjustment over the shorter of the remaining life of the contract or the
remaining period to maturity of the underlying instrument hedged.  If the
contract remained outstanding after termination of the hedged relationship,
subsequent changes in market value of the contract would be recognized in
"Interest expense".

     In March 1998, we entered into reverse interest rate swap contracts
associated with the issuance of the $400.0 million Senior Notes.
Specifically, we entered into $300.0 million in reverse interest rate
swap agreements in which we receive an average fixed interest rate of
6.4% and pay an average floating interest rate (5.3% at December 31,
1998).

     In October 1997, we entered into $500.0 million in interest rate swap
contracts associated with our $1,100.0 million in borrowing arising from
the acquisition of Coulter. In July 1998, we terminated a $150.0 million
interest rate swap agreement when the related Credit Facility debt was paid
with proceeds from the sale-leaseback of real estate.  The termination cost
was $2.3 million.  See Note 6 "Sale-leaseback of Real Estate". At December
31, 1998, we have $350.0 million in interest rate swap agreements in which
we receive an average floating interest rate (5.2% at December 31, 1998)
and pay an average fixed interest rate of 6.2%. The interest rate swaps are
accounted for as hedges.
     
     In October 1997, we also entered into $400.0 million in treasury rate
lock agreements to hedge the U.S. Treasury Note rate underlying an expected
refinancing.  In March 1998, in conjunction with the issuance of the $400.0
million Senior Notes, we paid $9.2 million to settle the treasury rate lock
agreements.

     The counterparties to our foreign currency and interest rate swap
contracts are major financial institutions.  Our company is exposed to
credit risk in the event of non-performance of these counterparties, which
event we believe is remote.  Nevertheless, we monitor our counterparty
credit risk and utilize netting agreements and internal policies to
mitigate this risk.  The disclosed derivatives are indicative of the volume
and types of instruments used throughout the year after giving
consideration to the increase in volume arising from the acquisition of
Coulter.  The market value of all derivative instruments amounted to an
unrecognized loss of $22.0 million and $8.0 million at December 31, 1998,
and 1997, respectively.


10.  Income Taxes

  The components of earnings (loss) before income taxes were:
<TABLE>
<CAPTION>
                               1998        1997        1996
                               ----        ----        ----                 
<S>                         <C>         <C>         <C>

U.S.                        $10.2       $(304.5)    $  42.5
Non-U.S.                     36.4          52.6        69.0
                            -----       -------     -------
                            $46.6       $(251.9)    $ 111.5
                            =====       =======     =======
</TABLE>

The provision (benefit) for income taxes consisted of the following:
<TABLE>
<CAPTION>
                               1998        1997        1996
                               ----        ----        ----                  
<S>                         <C>         <C>         <C> 

Current                                             
  U.S. federal              $   4.0     $   5.2     $   9.6
  Non-U.S.                      9.1         5.3        12.4
  U.S. state and
   Puerto Rico                 (1.1)        3.5         4.0
                               ----        ----        ----
Total current                  12.0        14.0        26.0
                                                    
Deferred                                            
  U.S. federal                  8.2         0.7         9.0
  Non-U.S.                     (7.1)       (2.2)        1.8
                               ----        ----        ----    
Total deferred, net             1.1        (1.5)       10.8
                               ----        ----        ----
Total                       $  13.1     $  12.5     $  36.8
                               ====        ====        ====
</TABLE>

     The reconciliation of the U.S. federal statutory tax rate to the
consolidated effective tax rate is as follows:
<TABLE>
<CAPTION>
                               1998        1997        1996
                               ----        ----        ----
<S>                           <C>         <C>         <C>

Statutory tax rate            35.0%       (35.0)%     35.0%
In-process research and                             
  development                   -          39.2        -
State taxes, net of U.S.                            
 tax 
 benefit                       0.4          0.1        0.4
Ireland and Puerto Rico
 income                      (21.1)        (2.0)      (6.8)
Goodwill                      14.1          0.2        -
Non-U.S. taxes                (0.2)         0.9        5.0
Foreign income taxed in                             
 the U.S., net of
 credits                       9.0          1.4       (2.8)
Other                         (9.1)         0.2        2.2
                              ----         ----       ---- 
Effective tax rate            28.1%         5.0%      33.0%
                              ====         ====       ====
</TABLE>

     Certain income of subsidiaries operating in Puerto Rico and Ireland is
taxed at substantially lower income tax rates than the U.S. federal
statutory tax rate. The lower rates reduced expected income taxes by
approximately $6.9 million in 1998, $5.1 million in 1997, and $7.6 million
in 1996.  Since April 1990, earnings from manufacturing operations in
Ireland are subject to a 10% tax. The lower Puerto Rico income tax rate
expires in July 2003;  however, the impending closure of the Puerto Rico
facility (as part of our restructuring plans) will shorten the period of
benefit.

     The components of the provision (benefit) for deferred income taxes
are:
<TABLE>
<CAPTION>
                               1998        1997        1996
                               ----        ----        ----
<S>                          <C>        <C>         <C>
Restructuring costs          $  2.6     $  (15.7)   $   3.0
Compensation                   22.1         18.7        -
Inventory                      (2.0)        (4.0)       -
Net operating loss
 carryforward                 (16.6)        (2.6)       -
International transactions     (7.1)         2.2        1.3
Intangibles                    (5.7)          -         -
Accelerated depreciation        -           (0.4)      (0.5)
Accrued expenses               16.6         (4.2)       3.3
Pension costs                  (3.5)         8.9        6.9
Post-employment/retirement
 benefits                      (0.7)        (1.7)      (1.7)
Other                          (4.6)        (2.7)      (1.5)
                             ------      -------    -------
   Total                     $  1.1      $  (1.5)   $  10.8
                             ======      =======    =======
</TABLE>

Net operating loss carryforwards expire at varying dates through 2018.
The tax effect of temporary differences which give rise to significant
portions of deferred tax assets and liabilities consists of the following
at December 31:
<TABLE>
<CAPTION>
                                           1998        1997
                                           ----        ----
<S>                                     <C>         <C>
Deferred tax assets                                 
 Inventories                            $   12.5    $   9.8
 Capitalized expenses                        0.8        0.7
 International                              35.4       22.7
 Tax credits (primarily R&D)                29.4       38.4
 Purchase and assumed liabilities
  (see Note 3)                              64.0       87.4
 Accrued expenses                           61.6       43.9
 Restructuring costs                        14.6       16.3
 Environmental costs                         3.1        4.8
 Post-employment/retirement benefits        42.5       38.6
 Other                                      12.5       30.5
                                           -----      -----
                                           276.4      293.1
Less: Valuation allowance                  (59.2)     (59.2)
                                           -----      -----         
Total deferred tax assets                  217.2      233.9
                                                    
Deferred tax liabilities                            
    Depreciation                            1.3         1.8
    Pension costs                           3.7         9.9
    Intangible assets                     134.8       140.4
    Fixed assets                           17.5        17.5
    Leases                                  8.6         9.9
    Deferred service contracts              1.8         3.2
    International transactions              7.9         6.4
    Other                                  23.9        32.1
                                          -----       -----
Total deferred tax liabilities            199.5       221.2
                                          -----       -----
Net deferred tax asset                  $  17.7     $  12.7
                                          =====       =====
</TABLE>

     Based upon our historical pretax earnings, adjusted for significant
items such as non-recurring charges, our management believes it is more
likely than not that we will realize the benefit of the existing net
deferred tax asset at December 31, 1998.  We believe the existing net
deductible temporary differences will reverse during periods in which we
generate net taxable income.  Certain tax planning or other strategies will
be implemented, if necessary, to supplement income from operations to fully
realize recorded tax benefits.

     At each December 31, 1998 and 1997 we recorded a valuation allowance
of $59.2 million, for certain deductible temporary differences for which it
is more likely than not that we will not receive future benefits.  The
change in the valuation allowance was $16.8 million and $27.9 million for
1998 and 1997, respectively.  The change in the valuation allowance was
primarily due to the acquisition of Coulter.

     Non-U.S. withholding taxes and U.S. taxes have not been provided on
approximately $182.2 million of unremitted earnings of certain non-U.S.
subsidiaries because such earnings are or will be reinvested in operations
or will be offset by credits for foreign income taxes paid.

11.  Stockholders' Equity

     We had been authorized, through 1998, to acquire our common stock to
meet the needs of our existing stock-related employee benefit plans.  Under
this program, we repurchased 1.0 million shares of our common stock during
1997.  We elected to discontinue this stock repurchase program in
connection with the Coulter acquisition, since the Credit Facility
generally prohibits market repurchase of the Company's stock. Therefore, in
1998, we did not repurchase any shares under this program. Treasury shares
have been, and are expected to continue to be, reissued to satisfy our
obligations under existing stock-related employee benefit plans.

     In January 1993 we created the Benefit Equity Fund ("BEF"), a trust
for pre-funding future stock-related obligations of employee benefit plans.
The BEF does not change these plans or the amounts of stock expected to be
issued for these plans.  The BEF is funded by existing shares in treasury
as well as from additional shares the Company purchases on the open market
over time.  While shares in the BEF are not considered outstanding for the
calculation of earnings per share, the participants of the Employee Stock
Purchase Plan exercise the related voting rights.  At December 31, 1998,
0.7 million shares remain in treasury of which 0.2 million are held by the
BEF.

12.  Employee Benefits

Incentive Compensation Plans

     In 1988, we adopted an Incentive Compensation Plan for our officers
and key employees, which provided for stock-based incentive awards based
upon several factors including Company performance.  This plan expired on
December 31, 1990, but options outstanding on that date were not affected
by such termination.  Pursuant to this plan, we granted options to purchase
approximately 0.8 million shares, with an expiration date of ten years from
the date of grant.

     We have also adopted the Incentive Compensation Plan of 1990 ("1990
Plan").  This 1990 Plan reserved shares of our common stock for grants of
options and restricted stock.

     In 1998, we adopted the 1998 Incentive Compensation Plan ("1998
Plan"), which replaced the 1990 Plan.  An initial 2.0 million shares have
been reserved under the 1998 Plan.  Granted options typically vest over
three years and expire ten years from the date of grant. Each year,
commencing January 1, 1999, the number of shares available under the plan
will increase by 1.5% of the number of common stock issued and outstanding
as of the prior December 31.  As of January 1, 1999, 2.4 million shares
remain available for grant under this plan.

     The following is a summary of the option activity, including weighted
average option information (in thousands, except per option information):
<TABLE>
<CAPTION>
                      1998               1997               1996
                         Weighted          Weighted             Weighted
                         Average            Average             Average
                         Exercise          Exercise             Exercise
                        Price Per          Price Per           Price Per
               Options    Option   Options  Option    Options    Option
               -------    ------   -------  ------    -------    ------
<S>             <C>     <C>          <C>    <C>       <C>       <C>
Outstanding                                                     
at beginning                                                    
of year          2,895  $28.60        2,672 $26.03    2,634     $ 22.83
                                                                
Granted          703    $42.56        536   $40.49    447       $ 40.72
                                                                
Exercised       (322)   $24.19       (302)  $26.77    (372)     $ 19.97
                                                                
Canceled         (34)   $38.93       (11)   $33.38    (37)      $ 37.12
Outstanding                                                     
at end of        3,242  $32.40        2,895 $28.60     2,672    $ 26.03
year
</TABLE>
<TABLE>
<CAPTION>
                                                                  

                           Weighted                             Weighted
                            Average     Weighted                Average
   Range of    Outstanding Exercise     Average    Exercisable  Exercise
   Exercise    at December   Price     Remaining   at December Price Per
    Price       31, 1998      Per     Contractual    31, 1998    Option
                            Option        Life         (a)
                                        (Years)
  <S>          <C>         <C>            <C>      <C>          <C>
  $11.47 to    125         $16.50         1.1      125          $16.50
    $17.21
  $17.21 to    661         $20.51         3.1      661          $20.51
    $22.95
  $22.95 to    531         $26.42         4.7      531          $26.42
    $28.69
  $28.69 to    342         $29.25         5.6      342          $29.25
    $34.42
  $34.42 to    450         $39.51         7.2      200          $39.44
    $40.16
  $40.16 to    1,055       $41.29         7.4      426          $41.09
    $45.90
  $45.90 to    42          $48.59         7.7      8            $48.19
    $51.64
  $51.64 to    36          $55.96         9.5      20           $57.38
    $57.38
               3,242                               2,313        
</TABLE>

     (a) Options exercisable at December 31, 1997 and 1996 (in thousands)
were 2,034 and 1,911, respectively.

     The following represents pro forma information as if the Company recorded
compensation cost using the fair value of the issued compensation
instrument under SFAS 123 (the results may not be indicative of the actual
effect on net earnings in future years):
<TABLE>
<CAPTION>
                                1998          1997         1996
                                ----          ----         ----
   <S>                         <C>            <C>          <C>
  Net earnings (loss) as
    reported                   $ 33.5         $(264.4)     $74.7
   Assumed stock compensation                             
    cost,
    net of tax                   (6.2)           (5.7)      (2.6)
                                -----           -----       ---- 
   Pro forma net
    earnings (loss)            $ 27.3         $(270.1)     $72.1
                                                          
   Diluted earnings (loss)                                
    per share as reported      $ 1.14         $ (9.58)     $2.58
   Pro forma diluted earnings                             
    (loss) per share           $ 0.93         $ (9.79)     $2.49

</TABLE>

     We use the Black-Scholes valuation model for estimating the fair value
of the compensation instruments.  The following represents the estimated
fair value of options granted and the assumptions used for calculation:
<TABLE>
<CAPTION>
                                  1998          1997         1996
                                  ----          ----         ----
    <S>                       <C>           <C>          <C>
   Weighted average                                      
    estimated
    fair value per option
    granted                   $  16.66      $  15.73     $  14.56
   Average exercise price                                
    per option granted        $  42.56      $  40.49     $  40.72
   Stock volatility              33.0%         22.0%        18.0%
   Risk-free interest rate        4.7%          5.9%         6.7%
   Option term - years            6.7          10.0         10.0
   Stock dividend yield           1.4%          1.4%         1.5%
</TABLE>

Stock Purchase Plan

      Our  stock  purchase plan allows all U.S. employees and employees  of
certain  subsidiaries  outside the U.S. to purchase  the  Company's  common
stock  at  favorable  prices and favorable terms.  Employee  purchases  are
settled  at  six-month  intervals as of  June  30  and  December  31.   The
difference  between  the  purchase price and fair value  is  not  material.
Employees  purchased 0.2 million shares during 1998 and 1.3 million  shares
remain available for use in the plan at December 31, 1998.

Stock Appreciation Rights

      In 1998 we awarded stock appreciation rights to certain employees  of
our  international  subsidiaries.  These  rights  vest  over  three  years.
Compensation  expense  for these rights are based on  changes  between  the
grant price and the fair market value of the rights.

Post-employment Benefits

      Effective January 1, 1994 the Company adopted Statement of  Financial
Accounting  Standards No. 112, "Employers' Accounting  for  Post-employment
Benefits"  ("SFAS 112").  This statement required the Company to  recognize
an  obligation for post-employment benefits provided to former or  inactive
employees, their beneficiaries and covered dependents after employment  but
before  retirement.   Additional  accruals  for  post-employment  benefits,
subsequent  to adopting SFAS 112, was approximately $1.7 million  in  1998,
$0.9  million in 1997 and $0.8 million in 1996.  The increase  in  1998  is
primarily  attributable  to  the addition of  former  or  inactive  Coulter
employees to the plan and changes in plan assumptions.

13.  Retirement Benefits

  In February 1998, FASB issued Statement of Financial Accounting Standards
No.  132,  "Employers Disclosures about Pensions and other  Post-retirement
Benefits,"  ("SFAS 132").  This statement amends portions of  Statement  of
Financial Accounting Standards No. 87, "Employers' Accounting for Pensions,
Statement  of Financial Accounting Standards No. 88, "Employers' Accounting
for  Settlements and Curtailments of Defined Benefit Pension Plans and  for
Termination  Benefits" and Statement of Financial Accounting Standards  No.
106,   "Employers'  Accounting  for  Postretirement  Benefits  Other   than
Pensions"  to  revise the disclosure requirements of these statements.   We
have adopted SFAS 132 beginning with this annual report.

Defined Benefit Pension Plans

      We  provide pension benefits covering the majority of our  employees.
Consolidated  pension expense was $15.5 million in 1998, $11.3  million  in
1997, and $18.3 million in 1996.

     Pension benefits for Beckman Coulter's domestic employees are based on
age,  years  of service and compensation rates.  Our funding policy  is  to
provide currently for accumulated benefits, subject to federal regulations.
Assets  of  the  plans  consist  principally  of  government  fixed  income
securities and corporate stocks and bonds.

      Certain of our international subsidiaries have separate pension  plan
arrangements,  which  include  both funded and  unfunded  plans.   Unfunded
foreign pension obligations are recorded as a liability on our consolidated
balance sheets. Pension expense for international plans was $6.6 million in
1998, $4.9 million in 1997, and $4.0 million in 1996.

Healthcare and Life Insurance Benefits

      We  presently provide certain healthcare and life insurance  benefits
for  retired U.S. employees and their dependents.  Eligibility for the plan
and  participant  cost sharing is dependent upon the participant's  age  at
retirement, years of service and retirement date.
     The   following  represents  required  disclosures  regarding  benefit
obligations  and  plan  assets  of the Pension  and  Post-Retirement  Plans
determined by independent actuarial valuations:
<TABLE>
<CAPTION>
                                                     Post-    
                                   Pension Plans  Retirement
                                                     Plans
                                    1998   1997    1998   1997*
                                    ----   ----    ----   ----
<S>                               <C>     <C>     <C>    <C>
Change in benefit obligation:                                
Benefit obligation at beginning
 of year                          $407.9  $359.1  $77.0  $46.7
Service cost                        11.9    9.9     2.5    1.2
Interest cost                       27.8   26.6     5.3    3.4
Actuarial loss (gain)               46.7   32.1    11.8   (0.2)
Benefits paid                      (20.5) (19.8)   (4.7)  (3.6)
Plan participant contribution        -       -      1.3    1.0
Amendments                           -       -       -    (1.2)
Acquisitions                         -       -     (2.0)  29.7
                                   -----   ----    ----   ----
Benefits obligation
  at end of year                  $473.8 $407.9   $91.2  $77.0
                                                          
Change in plan assets:                                    
                                                          
Fair value of plan assets at                              
  beginning of year               $408.9 $331.2   $  -   $ -
Employer contribution                0.4   30.5     3.5    2.6
Plan participant contribution       -       -       1.2    1.0
Actual return on plan assets        73.8   67.0      -     -
Benefits paid                      (20.5) (19.8)   (4.7)  (3.6)
                                   -----   ----    ----   ----
Fair value of plan assets
  at end of year                  $462.6 $408.9   $  -   $ -
                                                          
Funded status                     $(11.2)$  1.0   $(91.2)$(77.0)
Unrecognized net actuarial
 loss (gain)                        20.3   15.2     (4.6) (16.9)
Unrecognized net obligation at                            
 transition                          0.9    1.4      -      -
Unrecognized prior service cost      5.5    6.4     (1.0)  (1.1)
                                    ----   ----     ----   ----
Prepaid (accrued) benefit cost     $15.5 $ 24.0   $(96.8)$(95.0)
                                                          
Amounts recognized in the balance
 sheets
 consist of:
Prepaid benefit cost               $15.5 $24.0    $(96.8)$(95.0)
Accrued benefit liability           (0.4)   -       -      -
Intangible asset                     0.4    -       -      -
Net amount recognized              $15.5 $24.0    $(96.8)$(95.0)
</TABLE>

* Costs, actuarial loss and benefits paid represent 2 months
in 1997 for Coulter.

The  total  benefit obligation for unfunded pension plans included  in  the
above  table  was  $10.4  million  and  $9.8  million  in  1998  and  1997,
respectively.

     Coulter  has  provided for a non-qualified executive retirement  plan.
Information regarding this plan is not included in the tables  above.   The
unfunded benefit obligation was $3.1 million at December 31, 1998 and  $2.8
million at December 31, 1997.  The pension expense related to this plan was
$0.6 million in 1998 and $0.1 million for the two months ended December 31,
1997.
     The  following table lists the components of the net periodic  benefit
cost  of  the plans and the weighted-average assumptions as of December  31
for the periods indicated:
<TABLE>
<CAPTION>
                                                          
                              Pension Plans       Post-Retirement
                                                       Plans
                            1998   1997     1996     1998   1997*  1996
                            ----   ----     ----     ----   ----   ----      
<S>                        <C>     <C>     <C>       <C>    <C>    <C>
Service cost               $11.9   $9.9    $10.8     $2.5   $1.2   $1.4
Interest cost               27.8   26.6     25.7      5.3    3.4    3.3
Expected return on plan
 assets                    (34.2) (31.7)   (27.2)      -      -      -
Amortization                 3.4    1.5      5.0     (0.7)  (1.3)  (0.5)
                            ----   ----     ----     ----   ----   ----         
Net periodic benefit cost  $ 8.9   $6.3    $14.3     $7.1   $3.3   $4.2
                                                                    
Discount rate                6.3%   7.0%     7.8%     6.3%   7.0%   7.8%
Expected return on plan 
 assets                      9.8%   9.8%     9.8%      -       -     -
Rate of compensation
 increase                    4.3%   4.3%     4.3%      -       -     -
                                                                    
Healthcare cost trend rate    -      -        -       8.0%     -     -
Decreasing to ultimate                                              
 rate by
 the year 2004                -      -        -       5.5%     -     -
Decreasing to ultimate                                              
 rate by
 the year 2005                -      -        -       5.5%     -     -
Calculation of obligation,                                          
  excluding Coulter:                                                
Healthcare cost trend rate    -      -        -        -      8.0%   8.0%
Decreasing to ultimate                                              
 rate by
 the year 2004                -      -        -        -      5.5%   5.5%
Calculation of Coulter                                              
 obligation:
Healthcare cost trend rate    -      -        -        -      7.0%     -
Decreasing to ultimate                                              
 rate by the year 2002        -      -        -        -      5.0%     -
</TABLE>

* Costs, expected return and amortization paid represent 2 months
in 1997 for Coulter.

     An assumed 1% increase in the healthcare cost trend rate for each year
would have resulted in an increase in the net periodic pension cost by $1.4
million in 1998, $0.7 million in 1997, and $0.9 million in 1996, and in the
accumulated post-retirement benefit obligation by $13.7 million in 1998 and
$10.9 million in 1997.

    The  ongoing post-retirement plan has been recently amended to  provide
for  the  inclusion of Coulter employees and to conform benefit provisions.
Employees  outside  the  U.S.  generally  receive  similar  benefits   from
government-sponsored plans.

Defined Contribution Pension Plans

    We have defined contribution plans available to our domestic employees.
Under  the  plans,  eligible employees may contribute a  portion  of  their
compensation.  Employer contributions are primarily based on  a  percentage
of  employee  contributions.  However certain plans provide for  additional
contributions  based  on  the  age  and salary  levels  of  employees.   We
contributed  $14.9 million in 1998, $6.8 million in 1997, and $4.5  million
in  1996.  Employees generally become fully vested with respect to employer
contributions after three to five years of qualifying service as defined by
each plan.


14.  Commitments and Contingencies

Environmental Matters

      We  are  subject to federal, state, local and foreign environmental
laws  and  regulations.   Although we continue to make  expenditures  for
environmental   protection,   we  do  not  anticipate   any   significant
expenditure  in  order  to comply with such laws and  regulations,  which
would  have  a material impact on our operations, financial position,  or
liquidity.   We  believe  that  our operations  comply  in  all  material
respects  with applicable federal, state, local and foreign environmental
laws and regulations.

     To  address contingent environmental costs, we establish reserves when
the  costs are probable and can be reasonably estimated.  We believe, based
on  current information and regulatory requirements (and taking third party
indemnities into consideration), the reserves established for environmental
expenditures are adequate.  Based on current knowledge, to the extent  that
additional costs may be incurred that exceed the reserves, the amounts  are
not expected to have a material adverse effect on our operations, financial
position, or liquidity, although no assurance can be given in this regard.
     
     In  1983,  we discovered organic chemicals in the groundwater  near  a
waste   storage   pond  at  our  manufacturing  facility  in   Porterville,
California. Soil and groundwater remediation have been underway at the site
since  1983.   In 1989, the U.S. Environmental Protection Agency  issued  a
final  Record  of Decision specifying the soil and groundwater  remediation
activities  to  be conducted at the site.  We have completed  substantially
all  of  the  required  work. SmithKline Beckman,  our  former  controlling
stockholder,  agreed to indemnify us with respect to this  matter  for  any
costs incurred in excess of applicable insurance, eliminating any impact on
our  results  of operations, financial position, or liquidity.   SmithKline
Beecham  p.l.c., the surviving entity of the 1989 merger between SmithKline
Beckman  and Beecham, assumed the obligation of SmithKline Beckman in  this
respect.

     In 1987, soil and groundwater contamination was discovered on property
in  Irvine, California (the "property") formerly owned by us.  In 1988  The
Prudential Insurance Company of America ("Prudential"), which purchased the
property  from  us,  filed  suit  against us  in  U.S.  District  Court  in
California for recovery of costs and other alleged damages with respect  to
the  soil  and  groundwater contamination.  In  1990  we  entered  into  an
agreement  with  Prudential for settlement of the lawsuit and  for  sharing
current and future costs of investigation, remediation and other claims.

      Soil  and groundwater remediation of the property has been in process
since  1988.   During  1994  the County agency  overseeing  the  site  soil
remediation  formally  acknowledged completion of remediation  of  a  major
portion   of  the  soil,  although  there  remain  other  areas   of   soil
contamination  that  may require further remediation.   In  July  1997  the
California Regional Water Quality Control Board, the agency overseeing  the
site  groundwater remediation, issued a closure letter for the upper water-
bearing   unit.   The  Company  and  Prudential  continued  to  operate   a
groundwater  treatment system throughout 1998 and expect  to  continue  its
operation in 1999.

      Investigations  on  the property are continuing.   During  1998,  two
additional  areas of soil requiring remediation were identified.   Work  on
one  area  was  completed  in  1998.  Work on the  second  area  should  be
completed  during 1999. We can give no assurance that further investigation
will not reveal additional contamination or result in additional costs.  We
believe  that  additional remediation costs, if any, beyond  those  already
provided for the contamination discovered by the current investigation will
not  have a material adverse effect on our results of operations, financial
position, or liquidity.

Litigation

      We  are  involved in a number of lawsuits, which we consider ordinary
and  routine in view of our size and the nature of our business.  We do not
believe  that any ultimate liability resulting from any such lawsuits  will
have  a  material  adverse effect on our results of  operations,  financial
position,  or  liquidity.  However, we do not give  any  assurance  to  the
ultimate  outcome  with respect to such lawsuits.  The resolution  of  such
lawsuits  could  be  material to our operating results for  any  particular
period,  depending  upon the level of income for such  period.   Also,  see
environmental discussion above.

Lease Commitments

     We lease certain facilities, equipment and automobiles. Certain of the
leases  provide  for payment of taxes, insurance and other charges  by  the
lessee. Rent expense was $59.8 million in 1998,  $35.4 million in 1997, and
$32.9 million in 1996.

      As  of  December  31,  1998,  minimum annual  rentals  payable  under
non-cancelable operating leases aggregate $457.7 million, which is  payable
$52.8  million in 1999, $46.7 million in 2000, $40.0 million in 2001, $29.2
million in 2002, $21.4 million in 2003 and $267.6 million thereafter.

Other

      Under  our dividend policy, we pay a regular quarterly dividend  to
our  stockholders,  which amounted to $17.1 million  in  1998  and  $16.6
million in 1997.  In February of 1999, the Board of Directors declared  a
quarterly dividend of $0.16 per share, which approximates $4.6 million in
total.  This dividend is payable March 11, 1999 to stockholders of record
on  February  19,  1999.   The Credit Facility restricts  (but  does  not
prohibit) our ability to pay dividends.

15.  Earnings (Loss) Per Share

      In accordance with SFAS 128, the following is a reconciliation of the
numerators and denominators of the basic and diluted EPS computations.
<TABLE>
<CAPTION>
Year Ended December 31, 1998                      

                              Income      Shares        Per-Share
                            (Numerator)  (Denominator)   Amount
<S>                            <C>           <C>         <C>
Basic EPS                                           
Net earnings                   $ 33.5        28.0        $ 1.19
                                                    
Effect of dilutive stock                            
 options                          -           1.3         (0.05)
                                 ----        ----          ----               
Diluted EPS                                         
Net earnings                   $ 33.5        29.3        $ 1.14
                               ======        ====        ====== 
</TABLE>
<TABLE>
<CAPTION>
Year Ended December 31, 1997                      

                              Income      Shares         Per-Share
                            (Numerator)  (Denominator)     Amount
<S>                         <C>             <C>         <C>
Basic EPS                                           
Net loss                    $ (264.4)       27.6        $ (9.58)
                                                    
Effect of dilutive stock                            
 options                          -          -              -
                              ------        ----           -----           
Diluted EPS (1)                                     
Net loss                    $ (264.4)       27.6        $ (9.58)
</TABLE>

(1)Under GAAP, as we were in a net loss position in 1997, 1.0 common  share
equivalents were not used to compute diluted loss per share, as the  effect
was antidilutive.
<TABLE>
<CAPTION>
Year Ended December 31, 1996                      

                              Income      Shares         Per-Share
                            (Numerator)  (Denominator)     Amount
<S>                         <C>               <C>         <C>
Basic EPS                                           
Net earnings                $  74.7           28.0        $ 2.66
                                                    
Effect of dilutive stock                            
 options                        -              0.9         (0.08)
                             ------          -----          ----    
Diluted EPS                                         
Net earnings                $  74.7           28.9        $ 2.58
                             ======          =====          ====           
</TABLE>

16.  Business Segment Information

      We  adopted  Statement  of Financial Accounting  Standards  No.  131,
"Disclosures about Segments of an Enterprise and Related Information"("SFAS
131"), beginning with this annual report. SFAS 131 requires segments to  be
determined  and  reported based on how management measures performance  and
makes decisions about allocating resources.

      We  are  engaged  primarily in the design, manufacture  and  sale  of
laboratory  instrument systems and related products.  Our organization  has
two  reportable  segments: (1) clinical diagnostics and  (2)  life  science
research.    The   clinical  diagnostics  segment  encompasses   diagnostic
applications,  principally  in  hospital laboratories.   The  life  science
research segment includes life sciences and drug discovery applications  in
universities,   medical  schools,  and  pharmaceutical  and   biotechnology
companies.   All corporate activities including financing transactions  are
captured  in a central services "Center", which is reflected in the  tables
below.  We  evaluate performance based on profit or loss  from  operations.
Although primarily operating in the same industry, reportable segments  are
managed  separately,  since  each  business  requires  different  marketing
strategies and has different customers.
<TABLE>
<CAPTION>
For the years Ended           1998        1997        1996
December 31,
<S>                           <C>         <C>         <C>
Net sales                                           
  Clinical diagnostics        $ 1,342.5   $  815.2    $   652.0
  Life science research           375.7      382.8        376.0
  Center                            -           -           -
                                -------      -----        -----
     Consolidated               1,718.2    1,198.0      1,028.0
Operating income (loss)
  Clinical diagnostics            172.6     (149.3)       141.2
  Life science research            44.0       39.3         50.9
  Center (a)                     (101.8)    (127.0)       (69.6)
                                -------      -----        -----
      Consolidated (a)            114.8     (237.0)       122.5
Interest income                                     
  Clinical diagnostics             (9.8)      (2.7)        (2.0)
  Life science research              -           -           -
  Center                           (3.6)      (3.4)        (3.8)
                                -------      -----        -----
      Consolidated                (13.4)      (6.1)        (5.8)
Interest expense                                    
  Clinical diagnostics               -          -           -
  Life science research              -          -           -
  Center                           87.8        29.4        18.1
                                -------      ------       -----
      Consolidated                 87.8        29.4        18.1
Total assets                                        
  Clinical diagnostics           1,519.2     1,923.1       415.1
  Life science research           199.2       161.1       161.6
  Center                          414.9       246.8       383.4
                                -------      ------       -----
      Consolidated             $2,133.3    $2,331.0     $ 960.1
                                                    
Geographic areas

Sales to external                                   
 customers
 United States -- 
 domestic                      $  892.2    $  612.0    $  512.1
  United States -- export          75.9        60.8        36.0
  Europe                          462.3       333.7       316.7
  Asia and other areas            287.8       191.5       163.2
                                -------      ------       ----- 
 Consolidated                  $1,718.2    $1,198.0    $1,028.0
Long-lived assets                                   
  United States                $  808.8    $1,051.2    $  149.5
  Europe                          273.2       215.3       128.2
  Asia and other areas             94.6        87.8        52.1
                                -------     -------      ------ 
 Consolidated                  $1,176.6    $1,354.3    $  329.8
</TABLE>
                                                    
  (a)  Includes  restructuring charges of $19.1 million in 1998  and  $59.4
million in 1997.  We did not incur restructuring charges in 1996.


17.  Supplementary Information

Allowance for Doubtful Accounts
<TABLE>
<CAPTION>
                 Balance      Additions                         Balance
                   at        Charged to                         at End
                Beginning     Cost and     Deduc-     Other     of
                of Period     Expenses     tions                Period
                ---------     --------     -----      -----     ------
<S>      <C>     <C>          <C>          <C>        <C>       <C>
December 31,     $ 17.4       $  8.3(a)    $5.0(b)    $  -      $ 20.7
1998                                              
December 31,        9.6          2.4(a)     3.5(b)     9.4(d)     17.4
1997                                        0.5(c)
December 31,       9.1           2.2(a)     1.1(b)       -         9.6     
1996                                        0.6(c)
</TABLE>
(a)  Provision charged to earnings.
(b)  Accounts written-off.
(c)  Adjustments from translating at current exchange rates.
(d)  Allowance acquired as part of the Coulter acquisition.



QUARTERLY INFORMATION (Unaudited)
Tabular dollar amounts in millions, except amounts per share
<TABLE>
<CAPTION>
          First        Second        Third         Fourth        Full Year
          Quarter      Quarter       Quarter       Quarter
       1998   1997   1998   1997   1998   1997   1998   1997   1998     1997

<S>    <C>    <C>    <C>    <C>    <C>    <C>    <C>    <C>    <C>      <C>
Sales  $399.4 $231.9 $434.7 $270.6 $400.8 $271.6 $483.3 $423.9 $1,718.2 $1,198.0
                                                                         
Cost
of                                                                  
sales   229.8  109.6  236.5  130.7  207.0  132.1  247.3  237.3    920.6    609.7
                                                                         
Gross 
profit  169.6  122.3  198.2  139.9  193.8  139.5  236.0  186.6    797.6    588.3

Selling,                                                                 
general                                                                  
and     
adminis-
trative 119.7   74.8  123.6   79.7  120.2   82.9  128.8  122.9    492.3    360.3

Research                                                                 
and   
develop-
ment     41.6   24.0   42.2   28.6   41.2   27.7   46.4   43.3    171.4    123.6

In-                                                                      
process                                                                  
research
and
develop-
ment      -      -      -       -     -       -      -   282.0      -      282.0

Restruc-                                                                
turing
charge    -      -      -       -     -       -    19.1   59.4     19.1    59.4

Operating                                                                
income
(loss)    8.3    23.5   32.4   31.6   32.4  28.9   41.7 (321.0)   114.8  (237.0)

(Loss)
earnings                                                                 
before                                                                   
income
taxes   (12.4) 22.3   14.0   29.7   20.4  27.7   24.6   (331.6)    46.6  (251.9)

Net                                                                      
(loss)
earn-
ings   $(8.4)  $15.6  $9.5  $20.8  $13.9 $19.4  $18.5  $(320.2)   $33.5 $(264.4)

Basic                                                                    
(loss)                                                                   
earnings
per
share  $(0.30) $0.56  $0.34 $0.75  $0.49 $0.71  $0.65  $(11.63)   $1.19 $(9.58)

Diluted                                                                  
(loss)                                                                   
earnings
per
share  $(0.30) $0.54  $0.32 $0.72  $0.47 $0.68  $0.63  $(11.63)  $1.14  $(9.58)

Dividends                                                                
per
share  $0.15   $0.15  $0.15 $0.15  $0.15 $0.15  $0.16  $0.15     $0.61  $0.60
</TABLE>

<TABLE>
<CAPTION>
Stock                                                                    
price -                                                                  
High
<C>     <C>    <C>     <C>     <C>    <C>     <C>    <C>    <C>    <C>    
$60 7/16$44 3/8$59 7/16$49 3/16$63 5/8$52 5/16$54 1/4$44 1/2$63 5/8$52 5/16   
</TABLE>
<TABLE>
<CAPTION>
Stock                                                                    
price -
Low
<C>     <C>    <C>      <C>    <C>    <C>     <C>    <C>    <C>     <C> 
$41     $37 7/8$50 13/16$40 3/8$50    $39 3/4 $46 1/4$37 3/8$41     $37 3/8
</TABLE>
<TABLE>
<CAPTION>
Bar Chart:  Stock Price By Quarter 1998 
<S>              <C>         <C>          <C>        <C> 
Quarter          1st         2nd          3rd        4th

High             60 7/16     59 7/16      63 5/8     54 1/4
Low              41          50 13/16     50         46 1/4

Bar Chart:  Stock Price By Quarter 1997 

Quarter          1st        2nd          3rd         4th

High             44 3/8     49 3/16      52 5/16     44 1/2
Low              37 7/8     40 3/8       39 3/4      37 3/8


Bar Chart:  Sales By Quarter 1998 (millions)

Quarter          1st        2nd          3rd          4th
Sales            $399.4     $434.7       $400.8       $483.3


Bar Chart:  Sales By Quarter 1997 (millions)

Quarter          1st        2nd          3rd          4th
Sales            $231.9     $270.6       $271.6       $423.9
</TABLE>
<PAGE>

REPORT BY MANAGEMENT

     The consolidated financial statements and related information for
the years ended December 31, 1998, 1997, and 1996 were prepared by
management in accordance with GAAP.  Financial data included in other
sections of this Annual Report are consistent with that in the
consolidated financial statements.

     Management maintains a system of internal accounting controls, which
is designed to provide reasonable assurance, at appropriate costs, that
its financial and related records fairly reflect transactions, that
proper accountability for assets exists, and that established policies
and procedures are followed.  A professional staff of internal auditors
reviews compliance with corporate policies.  Among these policies is an
ethics policy, which requires employees to maintain high standards in
conducting the Company's affairs, and requires management level employees
to submit certificates of compliance annually.  Management continually
monitors the system of internal accounting controls for compliance and
believes the system is appropriate to accomplish its objectives.

     Our independent auditors examine our consolidated financial statements
in accordance with generally accepted auditing standards.  Their report
expresses an independent opinion on the fairness of our reported operating
results and financial position.  In performing this audit, the auditors
consider the internal control structure and perform such other tests and
auditing procedures as they deem necessary.

     The Board of Directors, through its Audit Committee, reviews both
internal and external audit results and internal controls.  The Audit
Committee consists of four outside Directors and meets periodically with
management, internal auditors and the independent auditors to review the
scope and results of their examinations.  Both the independent auditors
and the internal auditors have free access to this Committee, with and
without management being present, to discuss the results of their audits.

JOHN P. WAREHAM                              D.K. WILSON

John P. Wareham                              Dennis K. Wilson
Chairman, President and                      Vice President, Finance
Chief Executive Officer                      and Chief Financial Officer

<PAGE>

KPMG
Center Tower Drive
Costa Mesa, CA 92626



                  INDEPENDENT AUDITORS' REPORT

To the Stockholders and Board of Directors
Beckman Coulter, Inc.:

We have audited the accompanying consolidated balance sheets of 
Beckman Coulter, Inc. and subsidiaries as of December 31, 1998 and 1997,
and the related consolidated statements of operations, stockholders' 
equity and cash flows for each of the years in the three-year period ended
December 31, 1998.  These consolidated financial statements are the
responsibility of the Company's management.  Our responsibility is to
express an opinion on these consolidated financial statements based on our
audits.

We conducted our audits in accordance with generally accepted
auditing standards.  Those standards require that we plan and perform the
audit to obtain reasonable assurance about whether the financial 
statements are free of material misstatement.  An audit includes 
examining, on a test basis, evidence supporting the amounts and 
disclosures in the financial statements.  An audit also includes assessing
the accounting principles used and significant estimates made by
management, as well as evaluating the overall financial statement
presentation.  We believe that our audits provide a reasonable basis for
our opinion.

In our opinion, the consolidated financial statements referred to
above present fairly, in all material respsects, the financial position of
Beckman Coulter, Inc. and subsidiaries as of December 31, 1998 and 1997,
and the results of their operations and their cash flows for each of the
years in the three-year period ended December 31, 1998 in conformity with
generally accepted accounting principles.



KPMG LLP

Orange County, California
January 22, 1999




EXHIBIT 21


                             SUBSIDIARIES
                             ------------

The following table lists current subsidiaries of the Company
whose results are included in the Company's combined financial
statements. The list of subsidiaries does not include certain
subsidiaries which, when considered in the aggregate, do not
constitute a significant subsidiary of the Company.


                                                   Jurisdiction
Name of Company                                  of Incorporation
- ---------------                                  ----------------

Beckman Analytical S.p.A.                         Italy
Beckman Coulter Eurocenter S.A.                   Switzerland
Beckman Coulter Canada Inc.                       Canada

Beckman Instruments (Naguabo) Inc.                California
Beckman Instruments Espana S.A.                   Spain
Beckman Coulter France S.A.                       France

Beckman Coulter G.m.b.H.                          Germany
Beckman Coulter Hong Kong Ltd.                    Hong Kong
Beckman Instruments (Ireland) Inc.                Panama

Beckman Coulter K.K.                              Japan
Beckman Coulter United Kingdom Ltd.               England
Beckman Coulter International S.A.                Switzerland

Coulter Corporation                               Delaware
Coulter Electronics Industria E Comercia LTDA     Brazil
Beckman Coulter de Mexico S.A. de C.V.            Mexico

Coulter Scientific, Inc.                          Illinois
Hybritech Incorporated                            California





                                                                EXHIBIT 23

KPMG
Center Tower
650 Town Center Drive
Costa Mesa, CA 92626




                              Independent Auditors' Consent

The Stockholders and Board of Directors
Beckman Coulter, Inc.:

We consent to incorporation by reference in the registration statements
(No. 333-02317) on Form S-3 and (Nos. 333-24851, 333-37429, 33-31573,
33-41519, 33-51506, 33-66990, 33-66988, 333-72081, 333-69291, 333-59099,
333-69249 and 333-69251) on Form S-8 of Beckman Coulter, Inc. of our report
dated January 22, 1999, relating to the consolidated balance sheets
of Beckman Coulter, Inc. and subsidiaries as of December 31, 1998
and 1997, and the related consolidated statements of operations,
stockholders' equity, and cash flows for each of the years in the
three-year period ended December 31, 1998, which report appears in the
December 31, 1998 annual report on Form 10-K of Beckman Coulter, Inc.



KPMG LLP

Orange County, California
February 19, 1999




<TABLE> <S> <C>

<ARTICLE> 5
<LEGEND>
This schedule contains summary financial information extracted from the
Consolidated Balance Sheet and the Consolidated Statement of Operations and is
qualified in its entirety by reference to such financial statements.
</LEGEND>
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
<FISCAL-YEAR-END>                          DEC-31-1998
<PERIOD-END>                               DEC-31-1998
<CASH>                                              25
<SECURITIES>                                         0
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