CATALYTICA INC
DEF 14A, 1999-04-30
COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH
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                           SCHEDULE 14A INFORMATION
 
  Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of
                                     1934
                               (Amendment No.  )
 
Filed by the Registrant [X]
 
Filed by a Party other than the Registrant [_]
 
Check the appropriate box:
 
  [_]  Preliminary Proxy Statement
 
  [_]  Confidential for Use of the Commission Only (as permitted by Rule 14a-
       6(e)(2))
 
  [X]  Definitive Proxy Statement
 
  [_]  Definitive Additional Materials
 
  [_]  Soliciting Material Pursuant to (S) 240.14a-11(c) or (S) 240.14a-12
 
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                               CATALYTICA, INC.
               (Name of Registrant as Specified in its Charter)
 
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   (Name of Person(s) Filing Proxy Statement, if other than the Registrant)
 
Payment of Filing Fee (Check the appropriate box):
 
  [X]  No fee required.
 
  [_]  Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-
       11.
 
    (1) Title of each class of securities to which transaction applies:
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    (2) Aggregate number of securities to which transaction applies:
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    (3) Per unit price or other underlying value of transaction computed
        pursuant to Exchange Act Rule 0-11 (set forth the amount on which
        the filing fee is calculated and state how it was determined):
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    (4) Proposed maximum aggregate value of transaction:
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    (5) Total fee paid:
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  [_]  Fee paid previously with preliminary materials.
 
  [_]  Check box if any part of the fee is offset as provided by Exchange Act
       Rule 0-11(a)(2) and identify the filing for which the offsetting fee
       was paid previously. Identify the previous filing by registration
       statement number, or the Form or Schedule and the date of its filing.
 
    (1) Amount previously paid:
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    (2) Form, Schedule or Registration Statement No.:
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    (3) Filing Party:
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    (4) Date Filed:
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<PAGE>
 
                            [LOGO OF CATALYTICA]
 
                               ----------------
 
                   NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
 
                          To Be Held On June 24, 1999
 
TO THE STOCKHOLDERS:
 
   NOTICE IS HEREBY GIVEN that the 1999 Annual Meeting of Stockholders of
Catalytica, Inc., a Delaware corporation (the "Company" or "Catalytica"), will
be held on June 24, 1999, at 10:00 a.m., local time, in the Mandarin Oriental
Hotel, 222 Sansome Street, San Francisco, California 94101 for the following
purposes:
 
     1. To elect directors to serve for the following year and until their
  successors are duly elected.
 
     2. To ratify the appointment of Ernst & Young LLP as the Company's
  independent accountants for the 1999 fiscal year.
 
     3. To transact such other business as may properly come before the
  Annual Meeting or any adjournments thereof.
 
   Nominees for directors are set forth in the Proxy Statement accompanying
this Notice.
 
   Only stockholders of record at the close of business on April 30, 1999 are
entitled to notice of and to vote at the Annual Meeting.
 
   All stockholders are cordially invited to attend the Annual Meeting in
person. However, to assure your representation at the Annual Meeting, you are
urged to mark, sign, date and return the enclosed Proxy as promptly as
possible in the envelope enclosed for that purpose. Any stockholder attending
the Annual Meeting may vote in person even if he or she has previously
returned a Proxy.
 
                                          Sincerely,
                                          /s/ LAWRENCE W. BRISCOE
                                          LAWRENCE W. BRISCOE
                                          Vice President, Finance and
                                           Administration
                                          Chief Financial Officer
 
Mountain View, California
April 30, 1999
<PAGE>
 
                             [LOGO OF CATALYTICA]
 
                               ----------------
 
                                PROXY STATEMENT
 
                               ----------------
 
                      1999 ANNUAL MEETING OF STOCKHOLDERS
 
                INFORMATION CONCERNING SOLICITATION AND VOTING
 
General
 
   The enclosed Proxy is solicited on behalf of Catalytica, Inc. (the
"Company" or "Catalytica") for the 1999 Annual Meeting of Stockholders (the
"Annual Meeting") to be held on June 24, 1999, at 10:00 a.m., local time, in
the Mandarin Oriental Hotel, 222 Sansome Street, California 94101, or any
adjournment or adjournments thereof, for the purposes set forth herein and in
the accompanying Notice of Annual Meeting of Stockholders. The Company's
principal executive offices are located at 430 Ferguson Drive, Mountain View,
California 94043 and its telephone number is (650) 960-3000.
 
   These proxy solicitation materials and the Annual Report for the year ended
December 31, 1998 are expected to be mailed on or about June 1, 1999 to all
stockholders entitled to vote at the Annual Meeting.
 
Record Date and Outstanding Shares
 
   Only stockholders of record at the close of business on April 30, 1999 (the
"Record Date") are entitled to receive notice of and to vote at the Annual
Meeting. The outstanding voting securities of the Company as of April 30,
1999, consisted of 41,727,116 shares of Common Stock, which includes
13,270,000 shares of Class A Common Stock and excludes 11,730,000 shares of
non-voting Class B Common Stock. For information regarding holders of more
than 5% of the outstanding Common Stock of the Company, see "Proposal No. 1--
Election of Directors--Security Ownership of Principal Stockholders and
Management."
 
Revocability of Proxies
 
   The enclosed Proxy is revocable at any time before its use by delivering to
the Company a written notice of revocation or a duly executed Proxy bearing a
later date. If a person who has executed and returned a Proxy is present at
the Annual Meeting and wishes to vote in person, he or she may elect to do so
and thereby suspend the power of the proxy holders to vote his or her Proxy.
 
Voting and Solicitation
 
   Except as provided below with respect to cumulative voting, every
stockholder of record on the Record Date is entitled, for each share held, to
one vote on each proposal or item that comes before the Annual Meeting. In the
election of directors, each stockholder will be entitled to vote for seven
nominees, and the seven nominees receiving the greatest number of votes will
be elected.
 
   Every stockholder voting for the election of directors may cumulate such
stockholder's votes and give one candidate a number of votes equal to the
number of directors to be elected, multiplied by the number of votes to which
the stockholder's shares are entitled, or distribute the stockholder's votes
on the same principle among as many candidates as the stockholder thinks fit,
provided that votes cannot be cast for more than seven candidates. However, no
stockholder shall be entitled to cumulate votes unless the candidate's name
has been placed in nomination prior to the voting and the stockholder, or any
other stockholder, has given notice at the meeting prior to the voting of the
intention to cumulate the stockholder's votes.
<PAGE>
 
   The cost of this solicitation will be borne by the Company. The Company may
reimburse expenses incurred by brokerage firms and other persons representing
beneficial owners of shares in forwarding solicitation material to beneficial
owners. Proxies may be solicited by certain of the Company's directors,
officers and regular employees, without additional compensation, personally or
by telephone, telegram, letter, electronic mail or facsimile.
 
   Stockholders representing an aggregate of 20,863,558 shares of the
Company's Common Stock, including the Class A Common Stock, present or
represented by proxy at the Annual Meeting will constitute a quorum for
purposes of voting.
 
Deadline for Receipt of Stockholder Proposals
 
   Proposals of stockholders of the Company that are intended to be presented
by such stockholders at the Company's 2000 Annual Meeting of Stockholders must
be received by the Company no later than February 1, 2000 in order that they
may be considered for inclusion in the proxy statement and form of proxy
relating to that meeting.
 
   Pursuant to the Company's Bylaws, stockholders who wish to bring matters or
propose nominees for director at the Company's 2000 annual meeting of
stockholders must provide specified information in writing to the secretary of
the Company not less than 90 days nor more than 120 days prior to the first
anniversary of the 1999 annual meeting (i.e., June 24, 1999), unless such
matters are included in the Company's proxy statement pursuant to Rule 14a-8
under the Securities Exchange Act, as amended. If such stockholders fail to
comply with the foregoing notice provision, then the proxy holders will be
allowed to use their voting discretionary authority when the proposal is
raised at the 2000 Annual Meeting of Stockholders.
 
                                       2
<PAGE>
 
                     PROPOSAL NO. 1--ELECTION OF DIRECTORS
 
   At the Annual Meeting of Stockholders, a Board of seven directors is to be
elected. Unless otherwise instructed, the proxyholders will vote all of the
proxies received by them for the Company's seven nominees named below, all of
whom are currently directors of the Company. If any nominee of the Company is
unable or declines to serve as a director at the time of the Annual Meeting,
the proxies will be voted for any nominee who is designated by the current
Board of Directors to fill the vacancy. In the event that additional persons
are nominated for election as directors and if cumulative voting has been
properly invoked, the proxyholders intend to cumulate their votes and to vote
all proxies received by them in accordance with cumulative voting procedures
in such a manner as they believe will ensure the election of as many of the
nominees listed below as possible. In such event, the specific nominees for
whom such votes will be cast will be determined by the proxyholders. It is not
expected that any nominee will be unable or will decline to serve as a
director. Directors Hoffen and Goldberg are nominated to the Company's Board
of Directors pursuant to certain agreements. See "Transactions with
Management." The term of office of each person elected as a director will
continue until the next Annual Meeting of Stockholders and until a successor
has been elected and qualified.
 
Vote Required
 
   The seven nominees receiving the highest number of affirmative votes of the
shares entitled to be voted shall be elected to the Board of Directors. Votes
withheld from any director are counted for purposes of determining the
presence or absence of a quorum, but have no other legal effect under Delaware
law. The Company believes that both abstentions and broker non-votes should be
counted for purposes of determining whether a quorum is present at the Annual
Meeting. In the absence of controlling precedent to the contrary, the Company
intends to treat abstentions and broker non-votes with respect to the election
of directors in this manner.
 
   THE BOARD OF DIRECTORS RECOMMENDS THAT STOCKHOLDERS VOTE "FOR" EACH OF THE
NOMINEES LISTED BELOW.
 
Nominees
 
   The names of and certain information about the nominees of management are
set forth below:
 
<TABLE>
<CAPTION>
    Name of Nominee      Age        Position/Principal Occupation        Director Since
    ---------------      ---        -----------------------------        --------------
<S>                      <C> <C>                                         <C>
James A. Cusumano.......  56 Chairman of the Board and Chief Strategic        1974
                              Officer of the Company
Richard Fleming (2).....  74 President and Chief Executive Officer of         1985
                              Richard Fleming Associates, Inc.
Alan Goldberg...........  44 Managing Director of Morgan Stanley Dean         1997
                              Witter
Howard I. Hoffen          35 Managing Director of Morgan Stanley Dean         1997
 (1)(2).................      Witter
Ricardo B. Levy.........  54 President and Chief Executive Officer of         1974
                              the Company
Ernest Mario (1)........  60 Co-Chairman and Chief Executive Officer of       1996
                              ALZA
John A. Urquhart........  70 Senior Advisor to the Chairman of Enron          1997
                              Corp.
</TABLE>
- --------
(1) Member of the Compensation Committee
(2) Member of the Audit Committee.
 
   Except as set forth below, each of the nominees has been engaged in the
principal occupation described above during the past five years. There is no
family relationship between any of the directors or executive officers of the
Company.
 
   James A. Cusumano, a founder of Catalytica and a director since 1974,
served as President of the Company from its inception in 1974 until 1985, when
he assumed his current position of Chairman of the Board.
 
                                       3
<PAGE>
 
Dr. Cusumano served as the Company's Chief Technical Officer from 1985 through
October 29, 1998, when he assumed his current position as Chief Strategic
Officer of Catalytica, Inc. as well as its subsidiary, Catalytica
Pharmaceuticals, Inc. Dr. Cusumano has also served as President of Catalytica
Pharmaceuticals, Inc., a subsidiary of the Company from February 1995 until
October 29, 1998. Dr. Cusumano served as Director of Catalysis Research and
Development at Exxon Corporation's Corporate Research Laboratory from 1967 to
1974. Dr. Cusumano has a Ph.D. in physical chemistry from Rutgers University.
 
   Richard Fleming has been a director of Catalytica since 1985 and also
serves as an advisor and consultant to Catalytica. Mr. Fleming was President
and Chief Executive Officer of the Company from 1985 through August 1991. He
has served as President and Chief Executive Officer of Richard Fleming
Associates, Inc., a consulting firm, since May 1981 and was Vice Chairman for
Membership and Fiscal Affairs of the Chemical Industry Institute of Toxicology
until 1997. From 1969 to 1980, Mr. Fleming served at Air Products and
Chemicals, most recently as Executive Vice President, and from 1980 to 1981,
he served as President and Chief Operating Officer of GAF Corporation, a
multi-industry company. Mr. Fleming is also a director of Catalytica
Pharmaceuticals, Inc. Mr. Fleming has an M.S. in chemical engineering from New
York University.
 
   Alan E. Goldberg has been a director of Catalytica since August 1997. Mr.
Goldberg is Chairman and Chief Executive Officer of Morgan Stanley Dean Witter
Capital Partners, and Head of Morgan Stanley Dean Witter Private Equity. Mr.
Goldberg joined Morgan Stanley in 1979. He was elected Vice President in 1984
and in July 1984, he participated in the formation of the Private Equity
Business. He was promoted to Principal in 1986 and elected Managing Director
in 1988. Mr. Goldberg is Chairman and President of Morgan Stanley Leveraged
Equity Fund I, Inc., is a Managing Director and Director of Morgan Stanley
Leveraged Equity Fund II, Inc., and is a Managing Director and a Director of
Morgan Stanley Capital Partners III, Inc. He also serves as a Director of
Amerin Guaranty, Catalytica, Direct Response Corporation, Enterprise
Reinsurance, Equant N.V., Homeowners Direct, Smurfit-Stone Container
Corporation and LifeTrust America. Mr Goldberg received his B.A. in Philosophy
and Economics in 1975 from New York University. In 1979, he earned an M.B.A.
from New York University and a J.D. from Yeshiva University. Mr. Goldberg
became a member of the New York Bar in 1979.
 
   Howard I. Hoffen has been a director of Catalytica since August 1997. Mr.
Hoffen is a Managing Director of MSDW Capital Partners IV, Inc. and Morgan
Stanley Dean Witter. He joined Morgan Stanley in 1985 and Private Equity in
1986. He is a Managing Director of Morgan Stanley Capital Partners, Inc. and
of MSLEF II, Inc. Mr. Hoffen is a Director of Amerin Corporation, Somerset
Energy and Union Drilling. Mr. Hoffen has a B.S. from Columbia University and
an M.B.A. from the Harvard Business School.
 
   Ricardo B. Levy, a founder of Catalytica and a director since 1974, served
as Chief Operating Officer from the Company's inception in 1974 until August
1991, when he was promoted to his current position of President and Chief
Executive Officer. Mr. Levy is also a director of Catalytica Pharmaceuticals,
Inc. and Catalytica Combustion Systems, Inc. Prior to founding Catalytica, Dr.
Levy was a founding member of Exxon Corporation's Chemical Physics Research
Team. Dr. Levy is an alumnus of Princeton and Harvard University's Executive
Management Program and has a Ph.D. in chemical engineering from Stanford
University.
 
   Ernest Mario has been a director of Catalytica since 1996. Dr. Mario is Co-
Chairman of ALZA and has been Chief Executive Officer of ALZA since August
1993. Prior to joining ALZA, Dr. Mario was Deputy Chairman and Chief Executive
Officer of Glaxo Holdings p.l.c., and has served in a variety of executive
positions with Glaxo Inc. beginning in 1986. From 1977 to 1984, he held
various executive level positions with Squibb Corporation, ending as President
and Chief Executive Officer of Squibb Medical Products. Dr. Mario has a Ph.D.
and M.S. in physical sciences from the University of Rhode Island, and a B.S.
in pharmacy from Rutgers University.
 
   John A. Urquhart has been a director of Catalytica, Inc. since April 1997
and has served as a special board advisor to Catalytica Combustion Systems,
Inc., since July 1995. He currently serves as Senior Advisor to the Chairman
of Enron Corporation., a global integrated natural gas company, and has also
served as the Vice Chairman of Enron Corporation since 1990. Mr. Urquhart also
serves on a number of other corporate Boards of Directors, including Enron
Corp., Aquarion Company, Hubbell Incorporated, TECO Energy, Inc., Weir Group
 
                                       4
<PAGE>
 
PLC, and Tampa Electric Co. He previously served as the Senior Vice President
of Industrial and Power Systems at General Electric. In addition, he served
five years as a Committee Member on the Board of US Council for Energy
Awareness.
 
Security Ownership of Principal Stockholders and Management
 
   The following table sets forth, as of April 15, 1999, certain information
with respect to the beneficial ownership of the Company's Common Stock by (i)
each person known by the Company to own beneficially more than five percent of
the outstanding shares of Common Stock, (ii) each director of the Company,
(iii) each of the executive officers named in the table under "Executive
Compensation--Summary Compensation Table" and (iv) all directors and executive
officers as a group. Percentage beneficial ownership is based on 41,725,847
shares of common stock, which includes 13,270,000 shares of Class A common
stock, that are outstanding as of April 15, 1999. Except as otherwise
indicated in the footnotes to this table, the persons and entities named in
the table have sole voting and investment power with respect to all shares
beneficially owned, subject to community property laws, where applicable.
 
<TABLE>
<CAPTION>
                             Shares of Common
                                   Stock
                            Beneficially Owned
                           ---------------------
    Name of Person or                 Percentage
    Identity of Group        Number   Ownership
    -----------------      ---------- ----------
<S>                        <C>        <C>
Franklin Resources,
 Inc.....................   2,579,959    6.18%
 777 Mariners Island
 Blvd.
 San Mateo, California
 94404
 
Morgan Stanley Capital
 Partners III, L.P. (1)..  13,270,000   31.80%
 Alan Goldberg/Howard
 Hoffen
 1221 Avenue of the
 Americas
 New York, New York 10020
 
Ricardo B. Levy (2)......     837,316    2.00%
 c/o Catalytica, Inc.
 430 Ferguson Drive
 Mountain View,
 California 94043
 
James A. Cusumano (3)....     753,090    1.80%
 c/o Catalytica, Inc.
 430 Ferguson Drive
 Mountain View,
 California 94043
 
Richard Fleming (4)......     523,740    1.26%
 
Ralph Dalla Betta (5)....     435,872    1.04%
 
Lawrence W. Briscoe (6)..      86,496       *
 
Ernest Mario (7).........      19,222       *
 
John A. Urquhart (8).....      19,222       *
 
John M. Hart (9).........       6,667       *
 
All officers and
 directors as a group (10
 persons) (10)...........  15,951,625   38.00%
</TABLE>
- --------
 (1) Represents 13,270,000 voting shares of Class A stock held by Morgan
     Stanley Capital Partners III, L.P. and two affiliated funds. Excludes
     11,730,000 non-voting shares of Class B stock also held by Morgan
     Stanley. Mr. Goldberg and Mr. Hoffen are Managing Directors of Morgan
     Stanley Dean Witter. Mr. Goldberg and Mr. Hoffen disclaim beneficial
     ownership of the shares owned by Morgan Stanley.
 (2) Includes shares held by the following trusts, of which Dr. Levy serves as
     trustee: (i) 680,877 shares held by the Levy Family Trust; (ii) 37,348
     shares held by the Polly Jean Cusumano Trust; and (iii) 35,799 shares
     held by the Doreen Ann Nelson Trust. Dr. Levy disclaims beneficial
     ownership for the shares owned by the Polly Jean Cusumano Trust and the
     Doreen Ann Nelson Trust.
 
                                       5
<PAGE>
 
 (3) Includes shares held by the following trusts, of which Dr. Cusumano
     serves as trustee: (i) 488,232 shares held by the Cusumano Family Trust;
     (ii) 114,028 shares held by the Brian K. Levy Trust; and (iii) 115,350
     shares held by the Tamara Levy Trust. Dr. Cusumano disclaims beneficial
     ownership of the shares owned by the Brian K. Levy Trust and the Tamara
     Levy Trust.
 (4) Includes 5,333 shares issuable upon exercise of options held by Mr.
     Fleming, which options are exercisable within 60 days of April 15, 1999.
 (5) Includes 13,650 shares issuable upon exercise of options held by Dr.
     Dalla Betta, which options are exercisable within 60 days of April 15,
     1999.
 (6) Includes 66,496 shares issuable upon exercise of options held by Mr.
     Briscoe, which options are exercisable within 60 days of April 15, 1999.
 (7) Includes 19,222 shares issuable upon exercise of options held by Dr.
     Mario, which options are exercisable within 60 days of April 15, 1999.
 (8) Includes 19,222 shares issuable upon exercise of options held by Mr.
     Urquhart, which options are exercisable within 60 days of April 15, 1999.
 (9) Includes 6,667 shares issuable upon exercise of options held by Mr. Hart,
     which options are exercisable within 60 days of April 15, 1999.
(10) Includes 249,362 shares issuable upon exercise of options held by three
     directors and four executive officers, which options are exercisable
     within 60 days of April 15, 1999.
 
Board Meetings and Committees
 
   The Board of Directors of the Company held a total of four meetings during
the year ended December 31, 1998.
 
   The current members of the Audit Committee are Richard Fleming and Howard
I. Hoffen. The Audit Committee met twice during the year ended December 31,
1998. This Committee recommends engagement of the Company's independent public
accountants and is primarily responsible for approving the services performed
by such accountants and for reviewing and evaluating the Company's accounting
principles and its system of internal accounting controls.
 
   The Compensation Committee, which during the year ended December 31, 1998,
consisted of Directors Hoffen and Mario, met twice during the last fiscal
year. This Committee establishes the salary and incentive compensation of the
executive officers of the Company and the general compensation policies for
all employees. See "Report of the Compensation Committee of the Board of
Directors on Executive Compensation."
 
   The Nominating Committee, which for the year ended December 31, 1998,
consisted of Directors Fleming and Levy, did not meet during the past fiscal
year. The Nominating Committee reviews candidates and makes recommendations
for nominees to serve on the Board of Directors. If there are vacancies on the
Board of Directors, the Nominating Committee will consider nominees
recommended by stockholders. Candidates for consideration by the Nominating
Committee should be submitted to the attention of Dr. Levy at the Company by
no later than February 24, 2000. Any stockholder wishing to make a
recommendation to the Nominating Committee must submit the candidate's resume,
together with a statement describing why the candidate should be considered by
the Nominating Committee.
 
   During the fiscal year ended December 31, 1998, no Director attended fewer
than 75% of the aggregate of all meetings of the Board of Directors and any
committees on which such Director served except that Alan Goldberg attended
only 50% of the meetings held during the period for which he served as a
director during fiscal 1999.
 
Director Compensation
 
   Directors who are not officers of the Company, with the exception of Mr.
Hoffen and Mr. Goldberg, each receive an annual retainer for their services in
the amount of $20,000 per year, plus reimbursement of expenses. Mr. Fleming,
Dr. Mario and Mr. Urquhart each serve as Director for one of the subsidiaries
of the Company, as
 
                                       6
<PAGE>
 
well, and receive similar compensation for that service. During the fiscal
year ended December 31, 1998, Mr. Fleming, Dr. Mario and Mr. Urquhart each
received $40,000 in connection with their services as directors of the Company
and its subsidiaries.
 
   During the year ended December 31, 1998, the Company paid Richard Fleming
Associates, a consulting organization of which Richard Fleming, a Director of
the Company, is the President and Chief Executive Officer, approximately
$260,250. These payments were for services provided to the Company by Mr.
Fleming in his capacity as a consultant to the Company at a rate of $20,000
per month from January through December. Moreover, additional consulting fees
were paid for the period of July through September in the amount of $20,250 in
conjunction with further assistance provided to the Company on various
development programs and in identifying and investigating new business
opportunities.
 
   During the fiscal year ended December 31, 1998, Mr. Fleming, Dr. Mario and
Mr. Urquhart each received options to purchase 4,000 shares of Common Stock at
an exercise price of $11.875. Mr. Fleming's, Dr. Mario's and Mr. Urquhart's
options become exercisable at the rate of one-twelfth of the shares subject to
the option at the end of each month that the director remains on the Board
following the date of grant such that the options become fully vested within
one year of the date of grant.
 
   Certain directors who served on the board of directors of a subsidiary or
acted as a consultant to that subsidiary received stock options during the
fiscal year ended December 31, 1998. Mr. Fleming and Dr. Mario each received
options to purchase 5,000 shares of Catalytica Pharmaceuticals, Inc. at an
exercise price of $16.50. Mr. Urquhart received options to purchase 4,000
shares of Catalytica Combustion Systems, Inc. at an exercise prices of $12.00.
 
                                       7
<PAGE>
 
        Report of the Compensation Committee of the Board of Directors
                           on Executive Compensation
 
   The following is the Report of the Compensation Committee of the Company,
describing the compensation policies and rationale applicable to the Company's
executive officers with respect to the compensation earned by such executive
officers for the year ended December 31, 1998.
 
   The Compensation Committee of the Board of Directors of Catalytica
establishes the general compensation policies of the Company as well as the
compensation plans and specific compensation levels for executive officers.
The Compensation Committee during the year ended December 31, 1998 consisted
of two independent, non-employee Directors, Howard Hoffen and Ernest Mario.
 
   The Company's compensation philosophy is to provide a total compensation
package that will enable the Company to attract and retain top executive
talent, while emphasizing the linkage of compensation to corporate, business
and individual performance.
 
   The compensation program for the executive officers is identical to that
for all employees and consists of base salary, stock options and bonus. Other
benefits, such as health and welfare insurance, a defined contribution 401k
pension plan, and an employee stock purchase plan, are also available to all
eligible employees.
 
   The Compensation Committee establishes the compensation of the Chief
Executive Officer and the other executive officers based on several criteria
related to competitive compensation levels, the performance of the individual
and the company's performance relative to plan.
 
   Competitive Compensation. In order to establish competitive compensation, a
market basket of companies from both pharmaceuticals and combustion-related
industries was created and the base salaries, bonus opportunities and stock
option awards for their top executives were analyzed. The intent of the
Compensation Committee is to set the total compensation for the Company's
executive officers at approximately the 50th percentile of the market basket
of companies. Any such cross-company comparisons require some adjustments to
reflect varying levels of specific responsibilities, complexity of the
business, its ultimate potential and the background and training of the
incumbent. Such considerations set the base level of compensation assuming an
acceptable level of performance. Performance variations on an individual and
business level are then applied.
 
   Individual Performance. Personal performance is appraised against a budget
and business plan laid out at the beginning of each year. The plan includes a
set of personal objectives regarding such things as budgetary control,
achieving milestones in the Company's development programs, successful
execution and implementation of collaborative agreements or contracts,
achieving planned revenues and other criteria. Assessment of performance in
these regards determines the annual increase in base salary and also
determines, in part, the level of cash bonus and long term incentive
compensation. Bonus and options are also affected by corporate performance.
 
   Corporate Performance. Achievement of corporate objectives, designed to
enhance stockholder value, is a key factor in establishing stock option awards
and bonus. Typical corporate objectives would include profitable commercial
operation, sound management of all balance sheet items, appropriate balancing
of new opportunities and risks and the creation of profitable opportunities
for future business activity. The bonus plan for executives is based on the
achievement of a combination of financial and non-financial goals. The
financial portion of the bonus does not pay out below achievement of 95% of
the planned goal; it does, however, provide for over-achievement of the
financial objectives. Overall personal performance for 1998 was also taken
into consideration in the final bonus amount.
 
   In determining the Chief Executive Officer's compensation, the Committee
considered all of the above factors in relation to specific corporate plan and
CEO objectives and accomplishments in 1998, as well as progress toward longer
range Company goals under his leadership. The salary increase of 6.1% to
$350,000 was
 
                                       8
<PAGE>
 
effective March 1, 1999, the bonus of $315,000 for the 1998 calendar year, and
the option award of 34,500 shares on March 1, 1999 at an exercise price of
$14.25 per share, were all within the general guidelines we are following and
are consistent with the 1998 performance of the Company. In addition, the
Chief Executive Officer received Catalytica Combustion Systems, Inc. stock
options of 4,500 at an exercise price of $21.60 per share.
 
   The Company intends to take the necessary steps to comply with the $1
million compensation deduction limitation pursuant to Section 162(m) of the
Omnibus Reconciliation Act of 1993. In addition, the non-equity-based
compensation paid to the Named Officers in fiscal 1996, 1997 and 1998 did not
exceed $1 million for any individual.
 
                                          COMPENSATION COMMITTEE
 
                                          Howard I. Hoffen
                                          Ernest Mario
 
                                       9
<PAGE>
 
                               Performance Graph
 
   The following is a graph comparing the cumulative total return to
stockholders, calculated on a dividend reinvested basis, from December 31, 1993
through December 31, 1998, to the cumulative total return over such period of
(i) Nasdaq U.S. Stock Market Index and (ii) Standard and Poor Chemical
Specialty Index. The graph assumes that $100 was invested in the Company's
Common Stock at the initial public offering price, the Nasdaq U.S. Stock
Market, and in the Standard and Poor Chemical Specialty Index on December 31,
1993. Data for the Standard and Poor Chemical Specialty Index was unavailable
for dates in the middle of the month. The information contained in the
performance graph shall not be deemed to be "soliciting material" or to be
"filed" with the SEC, nor shall such information be incorporated by reference
into any future filing under the Securities Act or the Exchange Act, except to
the extent that the Company specifically incorporates it by reference into such
filing.
 
 
 
 
 
                        [PERFORMANCE GRAPH APPEARS HERE]
 
                                 1998 Baseline
 
<TABLE>
<CAPTION>
                          12/31/93 12/31/94 12/31/95 12/31/96 12/31/97 12/31/98
Data Points               -------- -------- -------- -------- -------- --------
<S>                       <C>      <C>      <C>      <C>      <C>      <C>
Catalytica, Inc.........  $   7.75 $   2.88 $   4.38 $   4.00 $  11.88 $  18.00
NASDAQ US Stock Market..   249.861  244.244  345.448  424.800  520.459  733.392
S&P Specialty Chemicals
 Index..................   259.644  222.576  287.943  291.167  354.117  295.727
</TABLE>
 
<TABLE>
<CAPTION>
Conversion to Index       12/31/93 12/31/94 12/31/95 12/31/96 12/31/97 12/31/98
Point                     -------- -------- -------- -------- -------- --------
<S>                       <C>      <C>      <C>      <C>      <C>      <C>
Catalytica, Inc.........    100       37       57       52      153      232
NASDAQ US Stock Market..    100       98      138      170      208      294
S&P Specialty Chemicals
 Index..................    100       86      111      112      136      114
</TABLE>
- --------
(1) Stock closing price on last business day of quarter
(2) Index Point = Data Point/Baseline X 100
 
                                       10
<PAGE>
 
                            Executive Compensation
 
   The following table sets forth the compensation paid by the Company with
respect to the years ended December 31, 1996, December 31, 1997, and December
31, 1998, to the Chief Executive Officer and each of the other four most
highly compensated executive officers (collectively, the "Named Officers") of
the Company:
 
Summary Compensation Table
 
<TABLE>
<CAPTION>
                                                    Long-Term
                                                   Compensation
                                                      Awards
                                                   ------------
                                      Annual
                                   Compensation
                                ------------------  Securities
   Name and Principal    Fiscal                     Underlying     All Other
        Position          Year  Salary($) Bonus($)  Options(#)  Compensation($)
   ------------------    ------ --------- -------- ------------ ---------------
<S>                      <C>    <C>       <C>      <C>          <C>
Ricardo B. Levy.........  1998  $330,000  $315,000    38,000        $33,450(1)
 President and            1997  $229,000  $ 76,000    60,000        $17,064(2)
 Chief Executive Officer  1996  $218,000  $  7,000    40,000        $17,264(3)
 
James A. Cusumano.......  1998  $300,000  $245,000     3,000        $29,547(1)
 Chairman of the Board
 and                      1997  $210,000  $ 64,000    60,000        $16,052(2)
 Chief Strategic Officer  1996  $206,000  $  4,140    10,000        $15,891(3)
 
Lawrence W. Briscoe.....  1998  $250,000  $178,000    19,000        $ 4,000(1)
 Vice President, Finance
 and                      1997  $198,000  $ 54,000   100,000        $ 4,000(2)
 Administration, and      1996  $188,000  $  4,500    35,000        $ 4,000(3)
 Chief Financial Officer
 
Ralph A. Dalla Betta....  1998  $166,000  $ 16,000     1,500        $11,680(1)
 Vice President and       1997  $162,000  $  3,000       --         $10,808(2)
 Chief Scientist          1996  $152,000  $  1,000    10,000        $10,640(3)
 
John M. Hart(4).........  1998  $ 85,432  $ 30,000    40,000            --
 Vice President,          1997       --        --        --             --
 Human Resources          1996       --        --        --             --
</TABLE>
- --------
(1) Includes (i) $4,000 contributed by the Company to each Named Officer's
    account under the defined contribution pension plan and (ii) the following
    amounts contributed by the Company to the Named Officer's account under
    the Supplemental Severance Benefits Plan: Dr. Levy $29,450; Dr. Cusumano
    $25,547; and Dr. Dalla Betta $7,680.
(2) Includes (i) $4,000 contributed by the Company to each Named Officer's
    account under the defined contribution pension plan and (ii) the following
    amounts contributed by the Company to the Named Officer's account under
    the Supplemental Severance Benefits Plan: Dr. Levy $13,064; Dr. Cusumano
    $12,052; and Dr. Dalla Betta $6,808.
(3) Includes (i) $4,000 contributed by the Company to each Named Officer's
    account under the defined contribution pension plan and (ii) the following
    amounts contributed by the Company to the Named Officer's account under
    the Supplemental Severance Benefits Plan: Dr. Levy $13,264; Dr. Cusumano
    $11,891; and Dr. Dalla Betta $6,640.
(4) Mr. Hart joined the Company on September 3, 1998. On an annualized basis,
    Mr. Hart's salary and bonus for 1998 would have been $220,000.
 
                                      11
<PAGE>
 
The Subsidiaries' Summary Stock Option Table
 
   The following table sets forth the stock options granted in each of the
company subsidiaries with respect to the years ended December 31, 1996,
December 31, 1997 and December 31, 1998 to the Company's Chief Executive
Officer and the Named Officers of the Company.
 
<TABLE>
<CAPTION>
                                            Long-Term Compensation Awards
                                ------------------------------------------------------
                                   Securities         Securities        Securities
   Name and Principal    Fiscal    Underlying         Underlying        Underlying
        Position          Year  CPI Options(#)(1) CCSI Options(#)(2) CAT Options(#)(3)
   ------------------    ------ ----------------- ------------------ -----------------
<S>                      <C>    <C>               <C>                <C>
Ricardo B. Levy.........  1998        2,000              2,400               --
 President and            1997       86,000             20,500               --
 Chief Executive Officer  1996        2,000              4,500             3,000
 
James A. Cusumano.......  1998       20,000              1,500               --
 Chairman of the Board
 and                      1997       80,000                --                --
 Chief Strategic Officer  1996       14,000              4,000             3,000
 
Lawrence W. Briscoe.....  1998        5,000              1,200               --
 Vice President, Finance
 and                      1997       30,000                --                --
 Administration, and      1996        1,600              4,000             3,000
 Chief Financial Officer
 
Ralph A. Dalla Betta....  1998          700             11,750               --
 Vice President and       1997          --                 --                --
 Chief Scientist          1996          --              25,000               --
 
John M. Hart............  1998       15,000             15,000               --
 Vice President,          1997          --                 --                --
 Human Resources          1996          --                 --                --
</TABLE>
- --------
(1) Represents long term compensation awards by Catalytica Pharmaceuticals,
    Inc. (CPI)
(2) Represents long term compensation awards by Catalytica Combustion Systems,
    Inc. (CCSI)
(3) Represents long term compensation awards by Catalytica Advanced
    Technologies, Inc. (CAT)
 
                                       12
<PAGE>
 
Company Option Grants in Last Fiscal Year
 
   The following table sets forth the stock options granted during the fiscal
year ended December 31, 1998 to each of the Named Officers:
 
<TABLE>
<CAPTION>
                                   Individual Grants(1)
                         -----------------------------------------
                                                                       Potential
                                                                      Realizable
                                                                   Value at Assumed
                         Number of  % of Total                      Annual Rates of
                         Securities  Options                          Stock Price
                         Underlying Granted to                     Appreciation for
                          Options   Employees  Exercise             Option Term(3)
                          Granted   in Fiscal   Price   Expiration -----------------
          Name             (#)(1)    Year(2)   ($/sh.)     Date     5%($)    10%($)
          ----           ---------- ---------- -------- ---------- -------- --------
<S>                      <C>        <C>        <C>      <C>        <C>      <C>
Ricardo B. Levy.........   38,000      6.7%     $12.81    4/1/08   $306,133 $775,802
James A. Cusumano.......    3,000      0.5%     $12.81    4/1/08   $ 24,168 $ 61,248
Lawrence W. Briscoe.....   19,000      3.3%     $12.81    4/1/08   $153,067 $387,901
Ralph A. Dalla Betta....    1,500      0.3%     $12.81    4/1/08   $ 12,084 $ 30,624
John M. Hart............   40,000      7.0%     $10.63    9/3/08   $267,406 $677,659
</TABLE>
- --------
(1) These options were granted under the Company's Stock Option Plan (the
    "Option Plan"). Options granted under the Option Plan generally have a
    ten-year term. Generally, 12.5% of the grant becomes exercisable six
    months after the date of grant. The balance of the grant then vests
    monthly, with full exercisability occurring on the fourth anniversary
    date. The per share exercise price is the Nasdaq closing price for the
    Company's Common Stock on the date of grant. Unless otherwise determined
    by the Board of Directors, the Option Plan provides for the automatic
    acceleration of vesting of all outstanding options (such that they become
    exercisable in full) in the event of a "change in control," as defined in
    the Option Plan.
(2) Based on options to purchase an aggregate of 570,785 shares granted to
    employees during 1998.
(3) Potential realizable value is based on an assumption that the stock price
    appreciates at the annual rate shown (compounded annually) from the date
    of grant until the end of the ten-year option term. These numbers are
    calculated based on the requirements promulgated by the SEC and do not
    reflect the Company's estimate of future stock price.
 
                                      13
<PAGE>
 
Subsidiary Option Grants in Last Fiscal Year
 
   The following table sets forth the stock options granted by the Company's
subsidiaries during the fiscal year ended December 31, 1998 to each of the
Named Officers:
 
<TABLE>
<CAPTION>
                                          Individual Grants(1)
                         ------------------------------------------------------
                                                                                    Potential
                                                                                   Realizable
                                                                                Value at Assumed
                                      Number of  % of Total                      Annual Rates of
                                      Securities  Options                          Stock Price
                                      Underlying Granted to                     Appreciation for
                                       Options   Employees  Exercise             Option Term(3)
                                       Granted   in Fiscal   Price   Expiration -----------------
          Name           Subsidiaries   (#)(1)    Year(2)   ($/sh.)     Date     5%($)    10%($)
          ----           ------------ ---------- ---------- -------- ---------- -------- --------
<S>                      <C>          <C>        <C>        <C>      <C>        <C>      <C>
Ricardo B. Levy.........     CPI         2,000      0.4%     $16.50    4/1/08   $ 20,754 $ 52,594
                             CCSI        2,400      1.3%     $12.00    4/1/08   $ 18,112 $ 45,900
 
James A. Cusumano.......     CPI        20,000      4.1%     $16.50    4/1/08   $207,535 $525,935
                             CCSI        1,500      0.8%     $12.00    4/1/08   $ 11,320 $ 28,687
 
Lawrence W. Briscoe.....     CPI         5,000      1.0%     $16.50    4/1/08   $ 51,884 $131,484
                             CCSI        1,200      0.6%     $12.00    4/1/08   $  9,056 $ 22,950
 
Ralph A. Dalla Betta....     CPI           700      0.1%     $16.50    4/1/08   $  7,264 $ 18,408
                             CCSI       11,000      5.9%     $12.00    4/1/08   $ 83,014 $210,374
                             CCSI          750      0.4%     $ 5.60   1/30/08   $  2,641 $  6,694
 
John M. Hart............     CPI        15,000      3.1%     $22.00    9/3/08   $207,535 $525,935
                             CCSI       15,000      8.0%     $14.50    9/3/08   $136,785 $346,639
</TABLE>
- --------
(1) These options were granted under each of Catalytica Pharmaceuticals (CPI)
    and Catalytica Combustion Systems, Inc. (CCSI) Stock Option Plans (the
    "Subsidiary Option Plans"). Options granted under the Subsidiaries Option
    Plans generally have a ten-year term and vest ratably over a four-year
    period. The per share exercise price is based on the fair market value of
    the subsidiary's common stock on the date of grant, as determined by the
    subsidiary's Board of Directors. Unless otherwise determined by the Board
    of Directors, the Subsidiary Option Plans provide for the automatic
    acceleration of vesting of all outstanding options (such that they become
    exercisable in full) in the event of a "change in control," as defined in
    the Subsidiary Option Plans.
(2) The percent of total options granted to employees during the fiscal year
    is based on the total number of options issued to employees at each
    particular subsidiary and is broken down accordingly. Particularly, the
    percent of total options granted to employees of Catalytica
    Pharmaceuticals during 1998 is based on options to purchase an aggregate
    of 492,255 shares and the percent of total options granted to employees of
    Catalytica Combustion Systems during 1998 is based on options to purchase
    an aggregate of 187,950 shares.
(3) Potential realizable value is based on an assumption that the stock price
    appreciates at the annual rate shown (compounded annually) from the date
    of grant until the end of a ten-year option term. These numbers are
    calculated based on the requirements promulgated by the SEC and do not
    reflect the Company's estimate of future stock price.
 
                                      14
<PAGE>
 
Company Aggregate Option Exercises in Last Fiscal Year and Fiscal Year-End
Values
 
   The following table sets forth for each of the Named Officers, information
with respect to stock options exercised during the fiscal year ended December
31, 1998 and stock options held at fiscal year end:
 
<TABLE>
<CAPTION>
                                                      Number of Securities
                                                     Underlying Unexercised     Value of Unexercised
                                                           Options at           In-the-Money Options
                           Shares                      Fiscal Year End(#)     at Fiscal Year End ($)(2)
                         Acquired on     Value      ------------------------- -------------------------
          Name           Exercise(#) Realized($)(1) Exercisable Unexercisable Exercisable Unexercisable
          ----           ----------- -------------- ----------- ------------- ----------- -------------
<S>                      <C>         <C>            <C>         <C>           <C>         <C>
Ricardo B. Levy.........      --             --       51,999       137,334     $581,578    $1,355,450
James A. Cusumano.......      --             --       24,333        64,667     $234,220    $  572,300
Lawrence W. Briscoe.....   33,000       $372,375      52,851       112,249     $673,608    $1,390,787
Ralph A. Dalla Betta....      --             --        7,871        15,205     $109,361    $  206,504
John M. Hart............      --             --          --         40,000          --     $  295,000
</TABLE>
- --------
(1) Market value of underlying securities on the exercise date minus the
    exercise price.
(2) Market value of underlying securities at December 31, 1998 minus the
    exercise price.
 
Subsidiary Aggregate Option Exercises in Last Fiscal Year and Fiscal Year-End
Values
 
   The following table sets forth for each of the Named Officers, information
with respect to subsidiary stock options exercised during the fiscal year
ended December 31, 1998 and stock options held at fiscal year end:
 
<TABLE>
<CAPTION>
                                          Number of Securities          Value of Unexercised
                                         Underlying Unexercised         In-the-Money Options
                                      Options at Fiscal Year End(#)   at Fiscal Year End ($)(2)
                                      ----------------------------- -----------------------------
          Name           Subsidiaries Exercisable (1) Unexercisable Exercisable (1) Unexercisable
          ----           ------------ --------------- ------------- --------------- -------------
<S>                      <C>          <C>             <C>           <C>             <C>
Ricardo B. Levy.........     CPI           40,167        61,833       $  644,475     $  883,325
                             CCSI          34,004        18,396       $  461,367     $  206,583
                             CAT              --         16,000              --             --
James A. Cusumano.......     CPI          154,292        79,708       $2,840,413     $1,011,787
                             CCSI          20,292         3,208       $  283,214     $   30,736
                             CAT              --         12,000              --             --
Lawrence W. Briscoe.....     CPI           41,592         5,008       $  768,490     $   30,890
                             CCSI          20,731         2,969       $  289,990     $   30,260
                             CAT              --         14,000              --             --
Ralph A. Dalla Betta....     CPI              117           583       $      410     $    2,040
                             CCSI          91,125        20,625       $1,259,696     $  184,479
                             CAT              --            --               --             --
John M. Hart............     CPI              --         15,000              --             --
                             CCSI             --         15,000              --             --
                             CAT              --            --               --             --
</TABLE>
- --------
(1) Subsidiaries Option Plans, except for Advanced Technologies, Inc. provide
    for stock option to be exercisable effective in 1998.
(2) Market value of underlying securities at December 31, 1998 minus the
    exercise price.
 
                                      15
<PAGE>
 
Compensation Committee Interlocks and Insider Participation
 
   The Compensation Committee consisted of Directors Hoffen and Mario in 1998.
No executive officer of the Company serves as a member of the board of
directors or on the compensation committee of any entity that has an executive
officer serving as a member of the Company's Board of Directors or
Compensation Committee.
 
   During the year ended December 31, 1998, the Company paid Richard Fleming
Associates, a consulting organization of which Richard Fleming, a Director of
the Company, is the President and Chief Executive Officer, approximately
$260,250. These payments were for services provided to the Company by Mr.
Fleming in his capacity as a consultant to the Company at a rate of $20,000
from January through December 1998 plus expenses and additional consulting for
the months of July through September in the amount of $20,250. Mr. Fleming
provided assistance to the Company on various development programs and in
identifying and investigating new business opportunities.
 
                                      16
<PAGE>
 
                         Transactions With Management
 
   Morgan Stanley Capital Partners III, Inc. In June 1997, the Company entered
into a Stock Purchase Agreement (the "Investment Agreement") with Morgan
Stanley Capital Partners III, Inc. and two other affiliated equity funds (the
"Morgan Stanley Equity Funds"), pursuant to which the Company sold 30,000,000
shares of Class A Common Stock and Class B Common Stock to the Morgan Stanley
Equity Funds for an aggregate purchase price of $120 million. The proceeds
were used to fund the acquisition of the pharmaceutical manufacturing facility
in Greenville, North Carolina. The Morgan Stanley Equity Funds are entitled to
certain registration rights, which came into effect on July 1, 1998, and
certain rights of repurchase held by the Morgan Stanley Equity Funds, which
will come into effect on July 1, 2005.
 
   The Investment Agreement also provides that the Morgan Stanley Equity Funds
are entitled to elect (i) 3 persons to the Company's Board of Directors for so
long as such funds own at least 30% of the outstanding Common Stock of the
Company, (ii) 2 persons to the Company's Board of Directors for so long as
such funds own between 10% and 30% of the outstanding Common Stock of the
Company or (iii) 1 person to the Company's Board of Directors for so long as
they own between 6% and 10% of the outstanding Common Stock of the Company.
(Common Stock assumes conversion of the Class A and Class B Common Stock into
Common Stock of the Company).
 
   In August 1997, pursuant to the Investment Agreement, the Company amended
its bylaws to increase the size of the Board of Directors from 7 to 9 and
appointed Messrs. Howard Hoffen and Alan Goldberg to the Board of Directors.
Messrs. Hoffen and Goldberg were subsequently elected as directors to the
Company's Board of Directors in connection with the 1998 Annual Meeting of
Stockholders. In April 1999, the Board of Directors amended its bylaws to
decrease the size of the Board of Directors from 9 to 7.
 
   With the proceeds received from exercise of warrants that the Company
distributed in August 1997 to its stockholders in connection with the
financing of the acquisition of the pharmaceutical manufacturing facility in
Greenville, North Carolina, the Company redeemed in October 1997 an aggregate
of 5,000,000 shares of Class B Common Stock held by the Morgan Stanley Equity
Funds at a redemption price of $4.75 per share.
 
   On April 21, 1999 the Company entered into Change of Control Severance
Agreements with the following members of Management: Ricardo Levy, James
Cusumano, Lawrence Briscoe and John Hart. The Change of Control Severance
Agreements provide for the following benefits in the event an officer is
involuntarily terminated (as defined in the Change of Control Severance
Agreement): (1) 200 percent of the officer's annual compensation plus a pro
rata payment of their projected bonus, (2) continued employee benefits for up
to 2 years from the date of an Involuntary Termination and (3) accelerated
vesting of all of the officers options.
 
Section 16(a) Beneficial Ownership Reporting Compliance
 
   Section 16(a) of the Securities Exchange Act of 1934, as amended ("Exchange
Act") requires the Company's executive officers, directors, and persons who
own more than 10% of a registered class of the Company's equity securities to
file reports of ownership and changes in ownership with the Securities and
Exchange Commission ("SEC") and the National Association of Securities
Dealers, Inc. Executive Officers, directors and greater than ten percent
stockholders are required by SEC regulation to furnish the Company with copies
of all Section 16(a) forms they file. Based solely in its review of the copies
of such forms received by it, or written representation from certain reporting
persons, the Company believes that, during fiscal year 1998, all reporting
persons complied with Section 16(a) filing requirements applicable to them
except that one Form 4 filed by Dr. Ricardo Levy was not timely with respect
to one transaction, which involved a sale of Common Stock.
 
                                      17
<PAGE>
 
      PROPOSAL NO. 2--RATIFICATION OF APPOINTMENT OF INDEPENDENT AUDITORS
 
   The Company has selected Ernst & Young, LLP independent accountants, to
audit the financial statements of the Company for the current fiscal year
ending December 31, 1999. Ernst & Young, LLP has audited the Company's
financial statements since the fiscal year ended December 31, 1982. A
representative of Ernst & Young, LLP is expected to be available at the Annual
Meeting to make a statement if such representative desires to do so and to
respond to appropriate questions.
 
   THE BOARD OF DIRECTORS RECOMMENDS VOTING "FOR" APPROVAL AND RATIFICATION OF
THE SELECTION OF ERNST & YOUNG, LLP IN THE EVENT THAT A MAJORITY OF THE VOTES
CAST AT THE MEETING ARE CAST AGAINST SUCH RATIFICATION, THE BOARD OF DIRECTORS
WILL RECONSIDER ITS SELECTION.
 
                                 OTHER MATTERS
 
   The Company does not currently intend to bring before the Annual Meeting
any matters other than those set forth herein, and has no present knowledge
that any other matters will or may be brought before the meeting by others.
However, if any other matters properly come before the meeting, it is the
intention of the persons named in the enclosed form of proxy to vote the
proxies in accordance with their judgment.
 
                                          BY ORDER OF THE BOARD OF DIRECTORS
                                          /s/ LAWRENCE W. BRISCOE
                                          Lawrence W. Briscoe
                                          Vice President, Finance and
                                           Administration,
                                          and Chief Financial Officer
 
Mountain View, California
April 30, 1999
 
                                      18
<PAGE>
 
- --------------------------------------------------------------------------------
          THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS
P
R                                  CATALYTICA, INC.
O 
X                  1999 ANNUAL MEETING OF STOCKHOLDERS
Y
                                 June 24, 1999

   The undersigned stockholder of Catalytica, Inc., a Delaware corporation,
hereby acknowledges receipt of the Notice of Annual Meeting of Stockholders and
Proxy Statement, each dated April 30, 1999, and hereby appoints Ricardo B. Levy
and Lawrence W. Briscoe, and each of them, proxies and attorneys-in-fact, with
full power to each of substitution, on behalf and in the name of the
undersigned, to represent the undersigned at the 1999 Annual Meeting of
Stockholders of Catalytica, Inc., to be held on Thursday, June 24, 1999, at
10:00 a.m., Pacific Daylight Savings Time, in the Mandarin Oriental Hotel
located at 222 Sansome Street, San Francisco, California 94101 and at any
continuation(s) or adjournment(s) thereof, and to vote all shares of Common
Stock that the undersigned would be entitled to vote if then and there
personally present, on the matters set forth on the reverse side and, in their
discretion, upon such other matter or matters that may properly come before the
meeting and any adjournment(s) thereof.

   THIS PROXY WILL BE VOTED AS DIRECTED OR, IF NO CONTRARY DIRECTION IS
INDICATED, WILL BE VOTED (1) FOR THE ELECTION OF DIRECTORS, (2) FOR THE
RATIFICATION OF THE APPOINTMENT OF ERNST & YOUNG LLP AS INDEPENDENT AUDITORS AND
(3) AS SAID PROXIES DEEM ADVISABLE ON SUCH OTHER MATTERS AS MAY PROPERLY COME
BEFORE THE MEETING.



- --------------------------------------------------------------------------------
COMMENTS/ADDRESS CHANGE: PLEASE MARK COMMENT/ADDRESS BOX ON THE REVERSE SIDE



                                    (Continued and to be signed on reverse side)
- --------------------------------------------------------------------------------
                             (FOLD AND DETACH HERE)

                              [LOGO OF CATALYTICA]

                         ANNUAL MEETING OF STOCKHOLDERS

                            Thursday, June 24, 1999
                                   10:00 a.m.

                            Mandarin Oriental Hotel
                               333 Battery Street
                         San Francisco California 94101
                                        
<PAGE>
 
- --------------------------------------------------------------------------------
THE BOARD OF DIRECTORS RECOMMENDS VOTING "FOR" EACH OF THE FOLLOWING PROPOSALS.

                                                               Please Mark  [X]
                                                               your votes as
                                                               indicated in
                                                               this example

                      FOR all nominees          WITHHOLD
                         listed (except as      for all
                           indicated)           nominees
1.   ELECTION OF DIRECTORS   [_]             [_]

IF YOU WISH TO WITHHOLD AUTHORITY TO VOTE FOR ANY INDIVIDUAL NOMINEE, STRIKE A
LINE THROUGH THAT NOMINEE'S NAME IN THE LIST BELOW:

James A. Cusumano, Richard Fleming, Alan Goldberg, Howard Hoffen,
Ricardo B. Levy, Ernest Mario and John A. Urquhart

<TABLE>
<CAPTION>
                                                                                FOR   AGAINST   ABSTAIN
 
<S>    <C>                                                                      <C>   <C>       <C>
2.     Proposal to approve and ratify the appointment of Ernst & Young, LLP     [_]      [_]      [_]
       as the independent auditors of the Company for the fiscal year 
       ending December 31, 1999.
 
 
3.     The proxies are authorized to vote in their discretion upon such other   [_]      [_]      [_]
       business as may properly come before the meeting.
 
                                   I PLAN TO ATTEND THE MEETING                                   [_]
 
                                     COMMENTS/ADDRESS CHANGE                                      [_]
                                     Please mark this if you have written
                                     comments/address on the reverse side
</TABLE>

Signature_____________________ Signature___________________ Date________________

(This Proxy should be marked, dated, signed by the stockholder(s) exactly as his
or her name appears hereon, and returned promptly in the enclosed envelope.
Persons signing in a fiduciary capacity should so indicate. If shares are held
by joint tenants or as community property, both should sign.)

- --------------------------------------------------------------------------------
                             (FOLD AND DETACH HERE)


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